T: Majority protein IDs Entry Name Protein names Gene Names Organism Gene Ontology (biological process) Gene Ontology (cellular component) Gene Ontology (molecular function) N: Q-value N: Score T: Peptide sequences BC-05 BTZ_1 BC-05 BTZ_2 BC-05 BTZ_3 BC-05 CFZ_1 BC-05 CFZ_2 BC-05 CFZ_3 BC-05 Ctr_1 BC-05 Ctr_2 BC-05 Ctr_3 BC-26 BTZ_1 BC-26 BTZ_2 BC-26 BTZ_3 BC-26 CFZ_1 BC-26 CFZ_2 BC-26 CFZ_3 BC-26 Ctr_1 BC-26 Ctr_2 BC-26 Ctr_3 SM-02 BTZ_1 SM-02 BTZ_2 SM-02 BTZ_3 SM-02 CFZ_1 SM-02 CFZ_2 SM-02 CFZ_3 SM-02 Ctr_1 SM-02 Ctr_2 SM-02 Ctr_3 A0A024RBG1 NUD4B_HUMAN Diphosphoinositol polyphosphate phosphohydrolase NUDT4B (DIPP-2B) (EC 3.6.1.52) (Nucleoside diphosphate-linked moiety X motif 4B) (Nudix motif 4B) (Nudix hydrolase 4B) NUDT4B Homo sapiens (Human) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process [GO:1901911]; diadenosine hexaphosphate catabolic process [GO:1901909]; diadenosine pentaphosphate catabolic process [GO:1901907]; diphosphoinositol polyphosphate metabolic process [GO:0071543] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] bis(5'-adenosyl)-hexaphosphatase activity [GO:0034431]; bis(5'-adenosyl)-pentaphosphatase activity [GO:0034432]; diphosphoinositol-polyphosphate diphosphatase activity [GO:0008486]; endopolyphosphatase activity [GO:0000298]; metal ion binding [GO:0046872]; RNA binding [GO:0003723] 0.22271 0.87761 LLGIFEQNQDRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.81189 0 0 0 0 10.9769 8.80129 0 0 9.27647 0 0 A0A075B6I7 LV548_HUMAN Probable non-functional immunoglobulin lambda variable 5-48 IGLV5-48 Homo sapiens (Human) adaptive immune response [GO:0002250]; immune response [GO:0006955] extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886] 0.88442 -0.29631 FSGSKDASTNAGILFISGL 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0477 0 A0A075B6P5 KV228_HUMAN Immunoglobulin kappa variable 2-28 IGKV2-28 Homo sapiens (Human) adaptive immune response [GO:0002250]; immune response [GO:0006955] extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886] 0.86154 0.091902 ASGVPDRFSGSGSGTDFTLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.27121 0 0 0 0 0 0 0 0 0 0 0 A0A075B6S6 KVD30_HUMAN Immunoglobulin kappa variable 2D-30 IGKV2D-30 Homo sapiens (Human) adaptive immune response [GO:0002250]; immune response [GO:0006955] extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886] 0.77251 0.27074 VSNWDSGVPDRFSGSGSGTDFTLK 0 0 0 0 0 0 0 0 0 9.87822 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0A087WSZ9 TVA30_HUMAN T cell receptor alpha variable 30 TRAV30 Homo sapiens (Human) adaptive immune response [GO:0002250]; response to bacterium [GO:0009617] T cell receptor complex [GO:0042101] 0.89702 -0.6744 ISASFNEKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.20095 0 0 0 0 A0A087WUL8 NBPFJ_HUMAN Neuroblastoma breakpoint family member 19 NBPF19 Homo sapiens (Human) cytoplasm [GO:0005737] 0.9475 -1.3545 LSRELLAEKEPEVLQDPLDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.42696 9.62892 0 0 0 A0A087WUV0 ZN892_HUMAN Zinc finger protein 892 ZNF892 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96671 -2.8407 EVSKAASQK 0 9.62505 0 0 0 0 0 9.82279 10.1123 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.934 0 A0A087WV53 SPEGN_HUMAN SPEG neighbor protein SPEGNB Homo sapiens (Human) 0.96936 -4.9322 ELRDGPK 0 0 0 0 8.45335 0 0 0 0 0 0 0 0 0 0 7.4088 0 0 0 0 0 0 0 0 0 0 0 A0A087WXM9 MEIKN_HUMAN Meiosis-specific kinetochore protein MEIKIN Homo sapiens (Human) "female meiosis chromosome segregation [GO:0016321]; homologous chromosome segregation [GO:0045143]; male meiosis chromosome segregation [GO:0007060]; meiotic sister chromatid cohesion involved in meiosis I [GO:0010789]; meiotic sister chromatid cohesion, centromeric [GO:0051754]" "condensed chromosome, centromeric region [GO:0000779]; kinetochore [GO:0000776]" 0.81242 0.22425 QGGSGSGPFSPR 0 0 0 0 0 0 0 0 0 0 9.02178 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0A096LNW5 NT2NR_HUMAN Notch homolog 2 N-terminal-like protein R (NOTCH2NL-related) NOTCH2NLR Homo sapiens (Human) calcium ion binding [GO:0005509] 0.82172 0.21744 GMCVTYHSGTGYCK 0 0 0 9.87231 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0A0A6YYD4 TVB13_HUMAN T cell receptor beta variable 13 TRBV13 Homo sapiens (Human) adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166] plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101] 0.9142 -0.78476 LSPDLPDSAWNTRLLCR 0 0 0 0 0 0 10.4627 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0A0A6YYG2 TVB66_HUMAN T cell receptor beta variable 6-6 TRBV6-6 Homo sapiens (Human) adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166] plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101] 0.57453 0.47382 LELAAPSQTSVYFCASSY 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.7458 0 0 0 0 0 0 0 0 0 10.8872 A0A0A6YYG3 TVB68_HUMAN T cell receptor beta variable 6-8 TRBV6-8 Homo sapiens (Human) adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166] plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101] 0.87003 0.033905 EVPNGYNVSR 0 0 0 0 0 0 0 0 0 0 9.20526 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0A0A6YYK6 TVA16_HUMAN T cell receptor alpha variable 16 TRAV16 Homo sapiens (Human) adaptive immune response [GO:0002250] T cell receptor complex [GO:0042101] 0.95266 -1.4676 ESIKGFTADLNK 0 0 0 0 0 0 0 0 9.72311 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0A0A6YYK7 TVA19_HUMAN T cell receptor alpha variable 19 (T-cell receptor alpha chain V region HPB-MLT) TRAV19 Homo sapiens (Human) adaptive immune response [GO:0002250]; immune response [GO:0006955] extracellular space [GO:0005615]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101] MHC protein binding [GO:0042287]; peptide antigen binding [GO:0042605] 0.90825 -0.74277 EDVTLDCVYETRDTTYYLFWYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0962 11.0356 A0A0B4J1W7 NPIA9_HUMAN Nuclear pore complex-interacting protein family member A9 NPIPA9 Homo sapiens (Human) nucleoplasm [GO:0005654] 0.96913 -3.0249 LDMKEIHTYMEMFQR 10.098 0 0 0 0 0 9.7687 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0A0B4J1Y9 HV372_HUMAN Immunoglobulin heavy variable 3-72 IGHV3-72 Homo sapiens (Human) adaptive immune response [GO:0002250] external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814] 0.88574 -0.33204 GLEWVGRTR 0 0 0 0 0 0 9.24963 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0A0B4J237 TVA82_HUMAN T cell receptor alpha variable 8-2 TRAV8-2 Homo sapiens (Human) adaptive immune response [GO:0002250] T cell receptor complex [GO:0042101] 0.80247 0.24115 GINGFEAEFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.64351 0 0 0 0 A0A0B4J276 TVA25_HUMAN T cell receptor alpha variable 25 TRAV25 Homo sapiens (Human) adaptive immune response [GO:0002250]; response to bacterium [GO:0009617] T cell receptor complex [GO:0042101] 0.48869 0.61839 LTFQFGEAKK 0 0 0 0 0 0 0 0 0 0 0 0 0 8.83371 0 0 0 0 0 0 0 0 0 0 0 0 0 A0A0B4J2F2 SIK1B_HUMAN Putative serine/threonine-protein kinase SIK1B (EC 2.7.11.1) (Salt-inducible kinase 1B) SIK1B Homo sapiens (Human) intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] cytoplasm [GO:0005737]; nucleus [GO:0005634] ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.97013 -3.2906 GLARQVCQVPASR 0 0 0 0 0 0 9.76115 0 9.61886 0 0 0 0 0 0 0 0 0 0 10.6324 0 0 0 0 0 0 0 A0A0C4DH41 HV461_HUMAN Immunoglobulin heavy variable 4-61 IGHV4-61 Homo sapiens (Human) adaptive immune response [GO:0002250] external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814] 0.69742 0.37512 GLEWIGYIYYSGSTNYNPSLK 0 0 0 10.2808 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0A0C4DH68 KV224_HUMAN Immunoglobulin kappa variable 2-24 IGKV2-24 Homo sapiens (Human) adaptive immune response [GO:0002250]; immune response [GO:0006955] extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886] 0.95012 -1.3833 ISNRFSGVPDR 0 0 0 0 0 0 0 0 0 0 0 0 9.41111 0 0 0 0 0 0 0 0 0 0 0 10.4386 9.86104 0 A0A0G2JS06 LV539_HUMAN Immunoglobulin lambda variable 5-39 IGLV5-39 Homo sapiens (Human) adaptive immune response [GO:0002250]; immune response [GO:0006955] extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886] 0.95602 -1.5876 YKSDSDK 0 0 0 0 0 0 9.69024 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0A0J9YWL9 TX13C_HUMAN Putative testis-expressed protein 13C TEX13C Homo sapiens (Human) metal ion binding [GO:0046872]; mRNA binding [GO:0003729] 0.95949 -1.9225 FSKSHSQK 0 0 0 0 0 0 0 0 0 0 0 0 9.58768 9.50524 0 0 0 0 0 10.1741 0 0 0 0 9.84789 0 0 A0A0J9YX94 PMA6F_HUMAN Paraneoplastic antigen Ma6F PNMA6F PNMA6BL Homo sapiens (Human) 0.93815 -1.2941 VFRKELGAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.3886 0 0 A0A0J9YY54 TX13D_HUMAN Testis-expressed protein 13D TEX13D Homo sapiens (Human) metal ion binding [GO:0046872]; mRNA binding [GO:0003729] 0.18471 0.95324 ARRMHTLVFR 0 0 0 0 0 0 0 0 0 9.12637 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.61796 0 A0A0K0K1G8 TVBJ2_HUMAN T cell receptor beta variable 10-2 TRBV10-2 Homo sapiens (Human) adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166] plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101] 0.93152 -1.2711 DAGITQSPRYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0775 0 0 0 0 0 0 A0A0U1RQG5 CT47C_HUMAN Cancer/testis antigen family 47 member C1 CT47C1 Homo sapiens (Human) 0.91321 -0.78679 WDEEAQDAAGKEEK 0 0 11.7407 0 0 0 0 0 0 0 0 0 0 0 9.75812 0 0 0 0 0 0 0 0 0 0 0 0 A0A0U1RQI7 KLF18_HUMAN Kruppel-like factor 18 KLF18 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.953 -1.4831 QKTQSCQFWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.779 0 0 0 0 A0A0U1RR37 CA232_HUMAN Uncharacterized protein C1orf232 C1orf232 Homo sapiens (Human) 0.89892 -0.644 GWLTMSSLFNKEDEDK 0 0 0 9.85505 10.1522 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0A0U1RRI6 CENL3_HUMAN Centromere protein V-like protein 3 (Centromere protein V pseudogene 3) CENPVL3 CENPVP3 Homo sapiens (Human) carbon-sulfur lyase activity [GO:0016846]; metal ion binding [GO:0046872] 0.34343 0.77061 AREAGSR 9.01959 0 0 0 0 0 0 0 0 0 11.4282 12.0129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0A1B0GTD5 TEX49_HUMAN Testis-expressed protein 49 TEX49 Homo sapiens (Human) 0.94831 -1.3628 KVLLKTFPNQVFR 0 0 8.9849 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0A1B0GTH6 CS2IP_HUMAN Casein kinase II subunit alpha'-interacting protein CSNKA2IP Homo sapiens (Human) nucleus [GO:0005634] 0.73013 0.33592 IVNSISNTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.65381 0 0 0 0 A0A1B0GTL2 CT204_HUMAN Uncharacterized protein C20orf204 C20orf204 PRR17 Homo sapiens (Human) 0.58467 0.46548 ALDAVATCWEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4531 A0A1B0GTR4 SPRR5_HUMAN Putative small proline-rich protein 5 SPRR5 Homo sapiens (Human) 0.84743 0.16723 QCAPPQQCCPPPQQR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4539 0 0 0 0 0 0 0 0 0 0 0 0 0 A0A1B0GTZ2 CC196_HUMAN Putative coiled-coil domain-containing protein 196 (Long intergenic non-protein coding RNA 238) CCDC196 C14orf53 LINC00238 NCRNA00238 Homo sapiens (Human) 0.71738 0.3648 IDDNYLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.78051 0 0 0 0 0 0 0 0 0 0 0 A0A1B0GU29 SIM28_HUMAN Small integral membrane protein 28 SMIM28 Homo sapiens (Human) membrane [GO:0016020] 0.90053 -0.69541 GLLGSSWKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4587 0 0 0 0 0 A0A1B0GUC4 MYCOS_HUMAN Myocilin opposite strand protein MYOCOS Homo sapiens (Human) 0.92716 -1.1897 EIITQKSDEAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4001 A0A1B0GUW6 SPEM3_HUMAN Uncharacterized protein SPEM3 SPEM3 Homo sapiens (Human) flagellated sperm motility [GO:0030317]; sperm individualization [GO:0007291] cytoplasm [GO:0005737]; membrane [GO:0016020] 0.97003 -3.106 HFFPKDK 0 8.7412 0 0 0 0 0 0 0 0 0 10.2623 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0A1B0GUX0 VAFNB_HUMAN Protein ATP6V1FNB (ATP6V1F neighbor gene protein) ATP6V1FNB Homo sapiens (Human) 0.96703 -3.7084 YRYLNTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0258 0 0 0 0 0 0 0 0 0 0 A0A1B0GV03 GG6L7_HUMAN Golgin subfamily A member 6-like protein 7 GOLGA6L7 Homo sapiens (Human) cis-Golgi network [GO:0005801] 0.96838 -3.6158 ASHQHQQALR 0 0 0 0 0 0 0 0 11.2035 0 0 0 0 0 0 0 0 10.2176 0 9.78929 0 0 0 0 0 0 0 A0A1B0GVG4 CC194_HUMAN Coiled-coil domain-containing protein 194 CCDC194 Homo sapiens (Human) 0.78861 0.25094 QLDQAESIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.63972 0 0 0 0 0 A0A1B0GVH7 IQCM_HUMAN IQ domain-containing protein M IQCM Homo sapiens (Human) 0.92309 -1.1027 DYYSKTFK 0 0 10.1459 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0A1B0GVN3 CB092_HUMAN Uncharacterized protein C2orf92 (Long intergenic non-protein coding RNA 1125) C2orf92 LINC01125 Homo sapiens (Human) membrane [GO:0016020] 0.92438 -0.98802 EQLTTIDK 0 0 0 0 0 0 10.9046 0 0 9.81381 0 0 0 0 0 0 0 0 9.65868 0 0 0 0 0 0 0 0 A0A1B0GVY4 SIM31_HUMAN Small integral membrane protein 31 SMIM31 Homo sapiens (Human) axon [GO:0030424]; membrane [GO:0016020] 0.91441 -0.79609 KNCSEEEHR 0 0 0 0 0 0 0 0 0 0 0 9.88554 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0A1B0GVZ2 F240B_HUMAN Protein FAM240B FAM240B Homo sapiens (Human) 0.95464 -1.5116 ELEEDRQER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.7717 0 0 A0A1B0GVZ6 MB3LB_HUMAN Methyl-CpG-binding domain protein 3-like 2B MBD3L2B Homo sapiens (Human) DNA methylation-dependent heterochromatin formation [GO:0006346]; negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] methyl-CpG binding [GO:0008327] 0.96961 -4.0155 AGAERVR 0 0 9.37541 0 0 9.42167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0A1W2PP97 THSD8_HUMAN Thrombospondin type-1 domain-containing protein 8 THSD8 Homo sapiens (Human) 0.9241 -1.0687 CLCDLGKQERSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7726 9.24474 9.97771 0 0 0 0 0 A0A1W2PPD8 KDM4F_HUMAN Probable lysine-specific demethylase 4F (EC 1.14.11.66) KDM4F Homo sapiens (Human) chromatin remodeling [GO:0006338] nucleus [GO:0005634] histone H3K9 demethylase activity [GO:0032454]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491] 0.94902 -1.3768 ISWAPDSSAGAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.99958 0 0 0 0 0 0 0 A0A1W2PPF3 DUXB_HUMAN Double homeobox protein B DUXB Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; transcription cis-regulatory region binding [GO:0000976]" 0.94813 -1.362 EFWRNRIQYNQSQK 0 0 0 0 0 0 0 0 9.70646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0A1W2PPK0 CPHL2_HUMAN Cytoplasmic polyadenylated homeobox-like protein 2 CPHXL2 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.91733 -0.85263 MSSQAFPAEEDHHNEERQTK 0 12.5148 0 12.351 12.4227 0 0 0 12.5362 11.7399 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0A1W2PPM1 CPHXL_HUMAN Cytoplasmic polyadenylated homeobox-like protein (Cytoplasmic polyadenylated homeobox 1) CPHXL CPHX1 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.9234 -1.0711 QSLSGAQRALMRR 0 0 0 0 0 9.52546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0A1W2PQ72 MSD7_HUMAN Myb/SANT-like DNA-binding domain-containing protein 7 MSANTD7 Homo sapiens (Human) 0.95506 -1.6115 DAVIAVRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1235 0 0 0 0 0 A0A1W2PQL4 ZN722_HUMAN Zinc finger protein 722 ZNF722 ZNF722P Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.63235 0.39949 AFKRHSSLAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.73134 0 0 0 0 0 0 0 0 0 0 0 A0A1W2PR19 GSTT4_HUMAN Glutathione S-transferase theta-4 (EC 2.5.1.18) (GST class-theta-4) (Glutathione S-transferase theta pseudogene 1) GSTT4 GSTTP1 Homo sapiens (Human) glutathione metabolic process [GO:0006749] cytoplasm [GO:0005737]; cytosol [GO:0005829] glutathione transferase activity [GO:0004364] 0.72889 0.33873 ITGEEVSAEK 0 0 0 0 0 0 0 0 9.04543 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0A1W2PR48 TLE7_HUMAN Transducin-like enhancer protein 7 TLE7 Homo sapiens (Human) negative regulation of canonical Wnt signaling pathway [GO:0090090] nucleus [GO:0005634]; transcription regulator complex [GO:0005667] transcription corepressor activity [GO:0003714] 0.88385 -0.12274 RAPQGSWKVGTLFHGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.8255 0 0 0 0 0 0 0 0 0 0 A0A1W2PR75 S72L6_HUMAN RNA polymerase II subunit A C-terminal domain phosphatase SSU72 like protein 6 (RNA polymerase II subunit A C-terminal domain phosphatase SSU72L6) (CTD phosphatase SSU72L6) (EC 3.1.3.16) SSU72L6 Homo sapiens (Human) mRNA polyadenylation [GO:0006378]; termination of RNA polymerase II transcription [GO:0006369] mRNA cleavage and polyadenylation specificity factor complex [GO:0005847] myosin phosphatase activity [GO:0017018]; RNA polymerase II CTD heptapeptide repeat phosphatase activity [GO:0008420] 0.87018 0.034499 VYDTVVEDLCSR 0 0 0 0 0 0 0 0 8.75368 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0A1W2PR82 PERC1_HUMAN Protein PERCC1 (Proline and glutamage-rich protein with a coiled coil domain) PERCC1 Homo sapiens (Human) digestive tract morphogenesis [GO:0048546]; enteroendocrine cell differentiation [GO:0035883] 0.91389 -0.76131 LARGGSLEDEDTPEPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.39577 0 0 0 0 0 0 0 0 A0A1W2PR95 IGB1C_HUMAN Immunoglobulin-binding protein 1 family member C IGBP1C IGBP1P2 Homo sapiens (Human) regulation of dephosphorylation [GO:0035303]; regulation of signal transduction [GO:0009966] cytosol [GO:0005829] protein phosphatase 2A binding [GO:0051721] 0.96699 -2.3175 ATPEEFRK 0 0 0 0 11.3608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.77813 A0A2R8Y2Y2 CHO90_HUMAN Uncharacterized protein C8orf90 C8orf90 Homo sapiens (Human) 0.88441 -0.14157 RLERLALSCAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.57437 0 0 0 A0A2R8Y7D0 TINCR_HUMAN Ubiquitin domain-containing protein TINCR (Placenta-specific protein 2) (Terminal differentiation-induced cornification regulator) TINCR LINC00036 NCRNA00036 PLAC2 Homo sapiens (Human) 0.9148 -0.79606 RAFYYNAR 0 0 0 0 0 0 0 0 0 0 8.7912 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0A2Z4LIS9 FXO3B_HUMAN Forkhead box protein O3B FOXO3B Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] cytosol [GO:0005829]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96535 -2.3757 GVLSSQDSPHFQEK 0 0 0 0 0 0 0 0 0 8.89515 0 10.1893 0 0 0 0 0 0 0 0 0 9.33136 0 0 0 0 0 A0A3B3IS91 PLGRF_HUMAN POLG alternative reading frame (POLGARF) (ORF-Y) [Cleaved into: POLGARF C-terminal fragment (POLGARFin)] POLGARF Homo sapiens (Human) extracellular space [GO:0005615]; nucleolus [GO:0005730] 0.91997 -0.92816 APAEARALGAASRALAR 0 0 14.531 9.47863 14.5113 14.4503 0 0 0 0 0 0 0 10.8684 14.7624 15.7769 0 0 0 10.6067 14.9989 14.8279 14.8393 10.7306 0 0 9.33042 A0A455ZAR2 PNT87_HUMAN Transcriptional regulator PINT87aa LINC-PINT Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] 0.91836 -0.87177 GAPGGWR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0112 0 0 0 0 0 8.05137 8.11666 0 0 9.53041 0 0 A0A494BZU4 T217B_HUMAN Putative transmembrane protein 217B TMEM217B Homo sapiens (Human) membrane [GO:0016020] 0.84824 0.17174 THICYEAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.22612 0 0 0 A0A494C071 PWWP4_HUMAN PWWP domain-containing DNA repair factor 4 PWWP4 Homo sapiens (Human) 0.96877 -6.9607 AIAPTPSALFR 0 10.5596 12.0559 9.4165 0 0 8.94991 0 0 9.46072 0 0 10.2758 0 0 0 0 10.5103 0 0 0 0 0 0 0 0 0 A0A494C086 SPD21_HUMAN Putative speedy protein E21 SPDYE21 Homo sapiens (Human) positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737] protein kinase binding [GO:0019901] 0.95487 -1.5193 AGLPSWQYQR 0 0 0 0 0 0 0 0 0 0 0 0 9.142 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0A494C1R9 TSPY9_HUMAN Testis-specific Y-encoded protein 9 TSPY9 TSPY9P Homo sapiens (Human) cell differentiation [GO:0030154]; gonadal mesoderm development [GO:0007506]; nucleosome assembly [GO:0006334]; spermatogenesis [GO:0007283] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleus [GO:0005634] chromatin binding [GO:0003682]; histone binding [GO:0042393] 0.91645 -0.77496 AAQALVCASAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0532 0 0 A0A578 TVB51_HUMAN T cell receptor beta variable 5-1 TRBV5-1 TCRBV5S1A1T Homo sapiens (Human) adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166] plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101] 0.92135 -1.0936 AGVTQTPR 0 0 0 0 0 0 0 0 0 9.91519 0 0 0 9.75171 0 0 0 0 0 0 0 0 0 0 0 0 0 A0A8I5KQE6 RPSA2_HUMAN Small ribosomal subunit protein uS2B (37 kDa laminin receptor precursor) (37LRP) (37/67 kDa laminin receptor) (LRP/LR) (40S ribosomal protein SA) (40S ribosomal protein SA2) (67 kDa laminin receptor) (67LR) (Laminin receptor 1) (LamR) (Laminin-binding protein precursor p40) (LBP/p40) RPSA2 RPSA RPSAP58 Homo sapiens (Human) ribosomal small subunit assembly [GO:0000028]; translation [GO:0006412] cytosolic small ribosomal subunit [GO:0022627]; nucleus [GO:0005634]; plasma membrane [GO:0005886] laminin binding [GO:0043236]; laminin receptor activity [GO:0005055]; structural constituent of ribosome [GO:0003735] 0 27.18 AIVAIENPADVSVISSR 8.93678 8.82566 8.80378 0 0 0 11.3492 11.7737 11.8851 9.8005 0 0 10.5576 9.55478 9.28186 11.5813 10.9988 9.82295 11.4052 10.0811 9.71334 11.397 8.74164 8.70172 12.922 12.9117 11.9385 A0AUZ9 KAL1L_HUMAN KAT8 regulatory NSL complex subunit 1-like protein (MSL1v2) KANSL1L C2orf67 Homo sapiens (Human) NSL complex [GO:0044545] histone acetyltransferase binding [GO:0035035] 0.96995 -4.1601 IQNSSRNTAR 0 0 0 0 0 0 10.4646 0 0 0 0 0 0 0 0 9.13814 0 9.53906 10.2016 0 0 0 0 0 0 0 11.3869 A0AVI2 FR1L5_HUMAN Fer-1-like protein 5 FER1L5 Homo sapiens (Human) regulation of neurotransmitter secretion [GO:0046928] plasma membrane [GO:0005886]; synaptic vesicle membrane [GO:0030672] calcium ion binding [GO:0005509] 0.96975 -5.0102 AEDEYEHEVDWWSK 0 0 0 0 10.1448 0 0 0 0 12.3793 12.7518 12.5068 0 0 0 0 0 0 0 0 0 0 0 0 0 8.82461 9.27561 A0AVI4 TM129_HUMAN E3 ubiquitin-protein ligase TM129 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TM129) TMEM129 Homo sapiens (Human) "protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; response to unfolded protein [GO:0006986]; retrograde protein transport, ER to cytosol [GO:0030970]; ubiquitin-dependent ERAD pathway [GO:0030433]" endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630] 0.9226 -1.1221 DRWACHPLAR 0 0 0 0 0 0 0 0 10.0724 0 0 0 0 0 0 0 0 0 0 0 0 0 9.85425 0 0 0 0 A0AVK6 E2F8_HUMAN Transcription factor E2F8 (E2F-8) E2F8 Homo sapiens (Human) cell cycle comprising mitosis without cytokinesis [GO:0033301]; chorionic trophoblast cell differentiation [GO:0060718]; fibroblast proliferation [GO:0048144]; hepatocyte differentiation [GO:0070365]; negative regulation of cytokinesis [GO:0032466]; negative regulation of transcription by RNA polymerase II [GO:0000122]; placenta development [GO:0001890]; positive regulation of DNA endoreduplication [GO:0032877]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; sprouting angiogenesis [GO:0002040]; trophoblast giant cell differentiation [GO:0060707] chromatin [GO:0000785]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; RNA polymerase II transcription regulator complex [GO:0090575] "cis-regulatory region sequence-specific DNA binding [GO:0000987]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity [GO:0001217]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96405 -2.2077 AASVNSRKDK 0 0 0 0 0 0 9.02301 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0AVT1 UBA6_HUMAN Ubiquitin-like modifier-activating enzyme 6 (Ubiquitin-activating enzyme 6) (EC 6.2.1.45) (Monocyte protein 4) (MOP-4) (Ubiquitin-activating enzyme E1-like protein 2) (E1-L2) UBA6 MOP4 UBE1L2 Homo sapiens (Human) amygdala development [GO:0021764]; dendritic spine development [GO:0060996]; hippocampus development [GO:0021766]; learning [GO:0007612]; locomotory behavior [GO:0007626]; protein modification by small protein conjugation [GO:0032446]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737]; cytosol [GO:0005829] ATP binding [GO:0005524]; FAT10 activating enzyme activity [GO:0019780]; nucleotidyltransferase activity [GO:0016779]; thiosulfate sulfurtransferase activity [GO:0004792]; ubiquitin activating enzyme activity [GO:0004839] 0.96187 -2.0718 DDDHNGHIDFITAASNLRAK 11.0324 10.7759 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.15957 A0FGR8 ESYT2_HUMAN Extended synaptotagmin-2 (E-Syt2) (Chr2Syt) ESYT2 FAM62B KIAA1228 Homo sapiens (Human) endocytosis [GO:0006897]; endoplasmic reticulum-plasma membrane tethering [GO:0061817]; lipid transport [GO:0006869] cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-plasma membrane contact site [GO:0140268]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; membrane [GO:0016020]; organelle membrane contact site [GO:0044232]; plasma membrane [GO:0005886] cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; identical protein binding [GO:0042802]; phosphatidylcholine binding [GO:0031210]; phosphatidylethanolamine binding [GO:0008429]; phosphatidylinositol binding [GO:0035091] 0.9618 -2.489 ACDLPAWVHFPDTERAEWLNK 0 0 0 0 0 11.5501 0 8.83216 9.7204 9.3926 8.75649 0 0 0 0 0 0 0 0 0 10.1236 0 0 0 0 0 0 A0JLT2 MED19_HUMAN Mediator of RNA polymerase II transcription subunit 19 (Lung cancer metastasis-related protein 1) (Mediator complex subunit 19) MED19 LCMR1 Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; RNA polymerase II preinitiation complex assembly [GO:0051123] core mediator complex [GO:0070847]; mediator complex [GO:0016592]; nucleus [GO:0005634] transcription coregulator activity [GO:0003712] 0.87406 0.024143 LHTGPLPEQCR 0 0 0 0 0 0 0 9.09091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0JNW5 BLT3B_HUMAN Bridge-like lipid transfer protein family member 3B (Syntaxin-6 Habc-interacting protein of 164 kDa) (UHRF1-binding protein 1-like) BLTP3B KIAA0701 SHIP164 UHRF1BP1L Homo sapiens (Human) early endosome to Golgi transport [GO:0034498]; intermembrane lipid transfer [GO:0120009] cytosol [GO:0005829]; early endosome [GO:0005769] GARP complex binding [GO:0062069]; lipid transfer activity [GO:0120013]; protein homodimerization activity [GO:0042803] 0.96176 -2.0519 FTKNLSPDK 9.79437 0 9.24809 0 0 0 0 0 0 10.2501 8.54013 9.1728 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0M8Q6 IGLC7_HUMAN Immunoglobulin lambda constant 7 (Ig lambda-7 chain C region) IGLC7 Homo sapiens (Human) adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853] external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; IgA immunoglobulin complex [GO:0071745]; IgD immunoglobulin complex [GO:0071738]; IgE immunoglobulin complex [GO:0071742]; IgG immunoglobulin complex [GO:0071735]; IgM immunoglobulin complex [GO:0071753]; plasma membrane [GO:0005886] 0.87182 0.028696 VGVETTKPSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.34981 0 0 0 0 0 0 0 0 A0MZ66 SHOT1_HUMAN Shootin-1 (Shootin1) SHTN1 KIAA1598 Homo sapiens (Human) "actin filament bundle retrograde transport [GO:0061573]; axonogenesis [GO:0007409]; Cdc42 protein signal transduction [GO:0032488]; cytoplasmic actin-based contraction involved in cell motility [GO:0060327]; endoplasmic reticulum polarization [GO:0061163]; netrin-activated signaling pathway [GO:0038007]; neuron projection morphogenesis [GO:0048812]; positive regulation of axon extension [GO:0045773]; positive regulation of neuron migration [GO:2001224]; Ras protein signal transduction [GO:0007265]; regulation of establishment of cell polarity [GO:2000114]; substrate-dependent cell migration, cell extension [GO:0006930]" axon [GO:0030424]; axonal growth cone [GO:0044295]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; filopodium [GO:0030175]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; microtubule cytoskeleton [GO:0015630]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471] actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinesin binding [GO:0019894] 0.16473 0.99033 ATQPETTEEVTDLKR 0 0 0 0 0 0 0 0 0 10.6515 0 0 0 0 0 9.49925 0 9.30316 0 0 0 0 0 0 0 0 0 A0PG75 PLS5_HUMAN Phospholipid scramblase family member 5 PLSCR5 Homo sapiens (Human) plasma membrane phospholipid scrambling [GO:0017121] plasma membrane [GO:0005886] phospholipid scramblase activity [GO:0017128] 0.90874 -0.74342 FTIQNANKEDILK 0 0 12.3146 0 0 10.7131 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0PJE2 DHR12_HUMAN Dehydrogenase/reductase SDR family member 12 (EC 1.1.-.-) (Short-chain dehydrogenase/reductase family 40C member 1) (Protein SDR40C1) DHRS12 SDR40C1 Homo sapiens (Human) oxidoreductase activity [GO:0016491] 0.96764 -2.7875 QAMPGFHARFGDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.70129 0 0 0 0 0 0 A0PJX0 CIB4_HUMAN Calcium and integrin-binding family member 4 CIB4 Homo sapiens (Human) calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287] 0.95432 -1.5316 LCPPGKYYK 0 0 0 0 0 0 0 0 0 0 0 9.24693 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0PJX2 TLDC2_HUMAN TLD domain-containing protein 2 (TBC/LysM-associated domain-containing protein 2) TLDC2 Homo sapiens (Human) response to oxidative stress [GO:0006979] nucleus [GO:0005634] 0.32516 0.78322 VFKWTGSNSFFVK 0 0 0 0 0 0 0 0 0 10.8525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0PJY2 FEZF1_HUMAN Fez family zinc finger protein 1 (Zinc finger protein 312B) FEZF1 FEZ ZNF312B Homo sapiens (Human) axon guidance [GO:0007411]; cell dedifferentiation [GO:0043697]; forebrain anterior/posterior pattern specification [GO:0021797]; interneuron migration [GO:1904936]; negative regulation of cell population proliferation [GO:0008285]; olfactory bulb development [GO:0021772]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of neuron differentiation [GO:0045666]; regulation of neurogenesis [GO:0050767]; regulation of transcription by RNA polymerase II [GO:0006357] cytosol [GO:0005829]; nucleoplasm [GO:0005654] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.72753 0.34146 DLSQAQLQHYMK 0 0 0 0 0 0 11.2095 11.2627 10.9936 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0PJZ0 A20A5_HUMAN Putative ankyrin repeat domain-containing protein 20A5 (Ankyrin repeat domain-containing protein 20A5 pseudogene) ANKRD20A5P ANKRD20A5 Homo sapiens (Human) 0.94096 -1.3149 KCQIDIYDKENR 0 0 0 0 0 0 9.22468 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A0PJZ3 GXLT2_HUMAN Glucoside xylosyltransferase 2 (EC 2.4.2.42) (Glycosyltransferase 8 domain-containing protein 4) GXYLT2 GLT8D4 Homo sapiens (Human) O-glycan processing [GO:0016266] membrane [GO:0016020] "UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase activity [GO:0140563]; UDP-xylosyltransferase activity [GO:0035252]" 0.96406 -2.2088 LARRPGEPR 0 0 0 0 0 0 0 0 0 0 12.4997 0 0 0 0 11.9453 0 0 0 0 0 0 0 0 0 0 0 A0PK05 TMM72_HUMAN Transmembrane protein 72 (Kidney-specific secretory protein of 37 kDa) TMEM72 C10orf127 KSP37 Homo sapiens (Human) membrane [GO:0016020] 0.89925 -0.61484 EGPSSLFIHMKSILK 0 0 0 0 0 0 0 0 0 0 0 0 8.87283 0 0 0 0 0 0 10.1075 0 0 0 0 0 0 0 A1A4S6 RHG10_HUMAN Rho GTPase-activating protein 10 (GTPase regulator associated with focal adhesion kinase 2) (Graf-related protein 2) (Rho-type GTPase-activating protein 10) ARHGAP10 GRAF2 Homo sapiens (Human) cytoskeleton organization [GO:0007010]; negative regulation of apoptotic process [GO:0043066]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] GTPase activator activity [GO:0005096] 0.96537 -2.7115 GLQPLEFSDCYLDSPWFRER 0 0 0 0 0 10.438 9.79591 0 0 11.4076 8.50613 0 0 0 9.7275 0 0 0 0 0 0 0 0 0 0 0 0 A1A4V9 CF119_HUMAN Cilia- and flagella-associated protein 119 (Coiled-coil domain-containing protein 189) CFAP119 C16orf93 CCDC189 Homo sapiens (Human) acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; sperm principal piece [GO:0097228] 0.96783 -2.8881 ASEERLSSK 9.39759 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.34789 0 0 0 0 0 0 0 A1A519 F170A_HUMAN Protein FAM170A (Zinc finger domain-containing protein) (Zinc finger protein ZNFD) FAM170A ZNFD Homo sapiens (Human) fertilization [GO:0009566]; positive regulation of DNA-templated transcription [GO:0045893]; transcription by RNA polymerase II [GO:0006366] nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.33504 0.77494 GVAVSWETEETLESLEK 0 0 0 0 0 0 9.19066 8.9987 0 0 0 0 0 0 0 0 0 9.29749 0 0 0 0 0 0 0 0 0 A1A5B4 ANO9_HUMAN Anoctamin-9 (Transmembrane protein 16J) (Tumor protein p53-inducible protein 5) (p53-induced gene 5 protein) ANO9 PIG5 TMEM16J TP53I5 Homo sapiens (Human) calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; calcium activated phosphatidylserine scrambling [GO:0061589]; chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; establishment of localization in cell [GO:0051649]; lipid metabolic process [GO:0006629]; monoatomic ion transmembrane transport [GO:0034220]; negative regulation of intracellular calcium activated chloride channel activity [GO:1902939] plasma membrane [GO:0005886] chloride channel activity [GO:0005254]; intracellular calcium activated chloride channel activity [GO:0005229]; phospholipid scramblase activity [GO:0017128] 0.96934 -3.3987 ADNSVFGLYR 0 0 0 0 0 0 0 10.7074 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1015 0 10.2997 0 0 0 A1A5C7 S22AN_HUMAN Solute carrier family 22 member 23 SLC22A23 C6orf85 Homo sapiens (Human) monoatomic ion transport [GO:0006811] plasma membrane [GO:0005886] transmembrane transporter activity [GO:0022857] 0.95917 -1.7589 GDNASNCDCRAWDYGIRAGLVQNVVSK 0 0 0 0 0 0 0 0 0 0 0 0 9.28526 0 0 0 0 0 0 0 0 0 0 9.12748 10.8467 0 10.8361 A1A5D9 BICL2_HUMAN BICD family-like cargo adapter 2 (Bicaudal D-related protein 2) (BICD-related protein 2) (BICDR-2) (Coiled-coil domain-containing protein 64B) BICDL2 BICDR2 CCDC64B Homo sapiens (Human) Golgi to secretory granule transport [GO:0055107]; vesicle transport along microtubule [GO:0047496] cytoplasm [GO:0005737] small GTPase binding [GO:0031267] 0.1015 1.1709 LQTTHEELLLLRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3327 0 12.1011 0 0 A1IGU5 ARH37_HUMAN Rho guanine nucleotide exchange factor 37 ARHGEF37 Homo sapiens (Human) cytoplasm [GO:0005737]; cytosol [GO:0005829] guanyl-nucleotide exchange factor activity [GO:0005085] 0.91358 -0.75735 QAGLNKDPR 9.64422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A1KZ92 PXDNL_HUMAN Probable oxidoreductase PXDNL (EC 1.-.-.-) (Cardiac peroxidase) (Inactive peroxidasin-like protein) (Polysomal ribonuclease 1) (PRM1) (Vascular peroxidase 2) PXDNL VPO2 Homo sapiens (Human) hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979] endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] endonuclease activity [GO:0004519]; heme binding [GO:0020037]; lactoperoxidase activity [GO:0140825]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601] 0.92307 -1.1619 LVATVWAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.106 0 0 0 0 0 0 0 11.4297 0 A1L020 MEX3A_HUMAN RNA-binding protein MEX3A (RING finger and KH domain-containing protein 4) MEX3A RKHD4 Homo sapiens (Human) cytosol [GO:0005829]; nucleus [GO:0005634]; P-body [GO:0000932] metal ion binding [GO:0046872]; RNA binding [GO:0003723] 0.80155 0.23944 GEEPVFMVTGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.15196 A1L0T0 HACL2_HUMAN 2-hydroxyacyl-CoA lyase 2 (EC 4.1.2.-) (Acetolactate synthase-like protein) (IlvB-like protein) ILVBL AHAS HACL2 Homo sapiens (Human) fatty acid alpha-oxidation [GO:0001561]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099] acetolactate synthase complex [GO:0005948]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; lyase activity [GO:0016829]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976] 0.949 -1.3753 GLLGRNHPLHIRENR 0 0 0 0 0 0 0 0 0 13.4804 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A1L157 TSN11_HUMAN Tetraspanin-11 (Tspan-11) TSPAN11 Homo sapiens (Human) membrane [GO:0016020] 0.9553 -1.5992 LSDELKQHLNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.35094 0 0 0 0 0 0 0 A1L168 CT202_HUMAN Uncharacterized protein C20orf202 C20orf202 Homo sapiens (Human) 0.91446 -0.81701 ADSAHWEDARSSGGTSPIR 0 0 9.57461 0 0 0 0 9.23489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A1L170 CA226_HUMAN Uncharacterized protein C1orf226 C1orf226 Homo sapiens (Human) 0.84518 0.15321 DSQDESK 0 10.1346 0 0 0 0 0 0 0 0 10.4626 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A1L190 SYCE3_HUMAN Synaptonemal complex central element protein 3 (Testis highly expressed gene 2 protein) (THEG-2) SYCE3 C22orf41 THEG2 Homo sapiens (Human) apoptotic process [GO:0006915]; cell division [GO:0051301]; ectopic germ cell programmed cell death [GO:0035234]; positive regulation of apoptotic process [GO:0043065]; positive regulation of developmental process [GO:0051094]; positive regulation of reproductive process [GO:2000243]; reciprocal meiotic recombination [GO:0007131]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130] central element [GO:0000801]; chromosome [GO:0005694]; nucleus [GO:0005634] 0.72997 0.3342 NWQELLHETK 0 0 0 0 0 0 0 0 0 0 10.2851 10.2397 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A1L390 PKHG3_HUMAN Pleckstrin homology domain-containing family G member 3 (PH domain-containing family G member 3) PLEKHG3 KIAA0599 Homo sapiens (Human) regulation of cell migration [GO:0030334]; regulation of establishment of cell polarity [GO:2000114]; regulation of small GTPase mediated signal transduction [GO:0051056] cytoskeleton [GO:0005856]; cytosol [GO:0005829] actin binding [GO:0003779]; guanyl-nucleotide exchange factor activity [GO:0005085]; small GTPase binding [GO:0031267] 0.96985 -5.3829 DPADPSQQGRVRNLR 0 12.4165 12.8511 0 0 0 0 0 0 0 11.9541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A1L3X0 ELOV7_HUMAN Elongation of very long chain fatty acids protein 7 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL7) (ELOVL fatty acid elongase 7) (ELOVL FA elongase 7) (Very long chain 3-ketoacyl-CoA synthase 7) (Very long chain 3-oxoacyl-CoA synthase 7) ELOVL7 Homo sapiens (Human) "fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; fatty acid elongation, saturated fatty acid [GO:0019367]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; sphingolipid biosynthetic process [GO:0030148]; unsaturated fatty acid biosynthetic process [GO:0006636]; very long-chain fatty acid biosynthetic process [GO:0042761]" endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789] 3-oxo-arachidoyl-CoA synthase activity [GO:0102336]; fatty acid elongase activity [GO:0009922]; very-long-chain 3-ketoacyl-CoA synthase activity [GO:0102756] 0.95941 -1.743 TVHLYDNWIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5764 0 0 0 0 0 0 0 11.0428 11.6869 0 A1L4H1 SRCRL_HUMAN Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D (Soluble scavenger protein with 5 SRCR domains) (SSc5D) SSC5D Homo sapiens (Human) defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterial lipoprotein [GO:0042494]; innate immune response [GO:0045087]; negative regulation of interleukin-8 production [GO:0032717] collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; membrane [GO:0016020] extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; scavenger receptor activity [GO:0005044] 0.92611 -1.209 APGKMPK 0 0 0 0 0 9.9634 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A1X283 SPD2B_HUMAN SH3 and PX domain-containing protein 2B (Adapter protein HOFI) (Factor for adipocyte differentiation 49) (Tyrosine kinase substrate with four SH3 domains) SH3PXD2B FAD49 KIAA1295 TKS4 Homo sapiens (Human) adipose tissue development [GO:0060612]; bone development [GO:0060348]; cell differentiation [GO:0030154]; extracellular matrix disassembly [GO:0022617]; eye development [GO:0001654]; heart development [GO:0007507]; podosome assembly [GO:0071800]; protein localization to membrane [GO:0072657]; skeletal system development [GO:0001501]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801] anchoring junction [GO:0070161]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; podosome [GO:0002102] "phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-5-phosphate binding [GO:0010314]; SH2 domain binding [GO:0042169]; superoxide-generating NADPH oxidase activator activity [GO:0016176]" 0.9618 -2.583 AQDRTGK 0 0 0 0 0 0 0 0 12.4647 0 0 0 0 0 0 0 0 0 0 0 9.06253 0 0 0 0 0 0 A1XBS5 CBAR1_HUMAN CBY1-interacting BAR domain-containing protein 1 CIBAR1 FAM92A FAM92A1 Homo sapiens (Human) cilium assembly [GO:0060271]; inner mitochondrial membrane organization [GO:0007007]; limb morphogenesis [GO:0035108]; membrane organization [GO:0061024]; membrane tubulation [GO:0097749]; positive regulation of smoothened signaling pathway [GO:0045880] centriole [GO:0005814]; ciliary basal body [GO:0036064]; ciliary base [GO:0097546]; ciliary transition zone [GO:0035869]; cytoplasm [GO:0005737]; extrinsic component of membrane [GO:0019898]; mitochondrial crista [GO:0030061]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; nucleus [GO:0005634] phospholipid binding [GO:0005543] 0.96248 -2.5494 AAMDASRTSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3723 0 0 A1Z1Q3 MACD2_HUMAN ADP-ribose glycohydrolase MACROD2 (MACRO domain-containing protein 2) (O-acetyl-ADP-ribose deacetylase MACROD2) (EC 3.5.1.-) ([Protein ADP-ribosylaspartate] hydrolase MACROD2) (EC 3.2.2.-) ([Protein ADP-ribosylglutamate] hydrolase MACROD2) (EC 3.2.2.-) MACROD2 C20orf133 Homo sapiens (Human) brain development [GO:0007420]; DNA damage response [GO:0006974]; peptidyl-glutamate ADP-deribosylation [GO:0140291]; protein de-ADP-ribosylation [GO:0051725]; purine nucleoside metabolic process [GO:0042278]; response to bacterium [GO:0009617] nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "ADP-ribosylglutamate hydrolase activity [GO:0140293]; deacetylase activity [GO:0019213]; hydrolase activity, acting on glycosyl bonds [GO:0016798]" 0.8815 -0.30728 APGEDTPRMPGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.66702 0 0 0 0 0 0 0 0 0 A2A288 ZC12D_HUMAN Probable ribonuclease ZC3H12D (EC 3.1.-.-) (MCP-induced protein 4) (Transformed follicular lymphoma) (Zinc finger CCCH domain-containing protein 12D) (p34) ZC3H12D C6orf95 MCPIP4 TFL Homo sapiens (Human) "3'-UTR-mediated mRNA destabilization [GO:0061158]; negative regulation of cell growth [GO:0030308]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; nuclear-transcribed mRNA catabolic process, RNase MRP-dependent [GO:0000294]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]" cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932] metal ion binding [GO:0046872]; mRNA binding [GO:0003729]; RNA endonuclease activity [GO:0004521] 0.96205 -2.0374 EHPSKMEFFQKLGYDR 10.3923 0 10.5894 0 0 0 0 10.5446 10.4819 10.7641 0 10.6647 0 9.57613 0 0 0 0 0 0 0 0 0 0 0 0 0 A2A2Z9 AN18B_HUMAN Ankyrin repeat domain-containing protein 18B ANKRD18B Homo sapiens (Human) 0.96412 -2.437 DIYGNTALHYAVYNEGTSLAER 0 10.3285 0 0 0 0 9.45241 0 9.92441 0 0 0 0 10.6519 0 0 0 8.79718 0 0 0 0 10.2423 10.0433 0 0 0 A2A3L6 TTC24_HUMAN Tetratricopeptide repeat protein 24 (TPR repeat protein 24) TTC24 Homo sapiens (Human) 0.9629 -2.1802 AAALALGAAAGCMLKSGRHR 0 0 0 0 0 0 0 0 0 9.78937 0 0 0 0 11.4441 0 0 9.46483 0 0 0 0 0 0 0 0 0 A2A3N6 PIPSL_HUMAN Putative PIP5K1A and PSMD4-like protein (PIP5K1A-PSMD4) PIPSL PSMD4P2 Homo sapiens (Human) cytoplasm [GO:0005737] phosphatidylinositol phosphate kinase activity [GO:0016307] 0.89818 -0.59311 LTAFVNTLNGK 0 0 0 0 0 0 0 9.20587 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.82018 0 0 A2AJT9 BCLA3_HUMAN BCLAF1 and THRAP3 family member 3 BCLAF3 CXorf23 Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944] mediator complex [GO:0016592]; mitochondrion [GO:0005739] DNA binding [GO:0003677]; transcription coregulator activity [GO:0003712] 0.96989 -4.4115 EPARNPK 0 0 0 0 0 0 0 0 0 9.32663 0 0 0 0 0 0 0 0 0 0 0 9.71937 0 0 0 0 0 A2CJ06 DYTN_HUMAN Dystrotelin DYTN Homo sapiens (Human) synaptic signaling [GO:0099536] plasma membrane [GO:0005886]; synapse [GO:0045202] zinc ion binding [GO:0008270] 0.94794 -1.3625 GGYDSGPRMTR 9.92788 9.76671 0 0 0 0 10.0668 10.0027 0 0 8.58226 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A2IDD5 CCD78_HUMAN Coiled-coil domain-containing protein 78 (hsCCDC78) CCDC78 C16orf25 JFP10 Homo sapiens (Human) cell projection organization [GO:0030030]; de novo centriole assembly involved in multi-ciliated epithelial cell differentiation [GO:0098535]; skeletal muscle contraction [GO:0003009] centriole [GO:0005814]; cytoplasm [GO:0005737]; deuterosome [GO:0098536]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]; sarcoplasmic reticulum [GO:0016529] 0.96693 -2.3525 HPRAAAQELRHK 0 0 0 0 0 0 8.7149 0 0 0 0 0 0 9.65132 0 0 0 0 10.3008 10.368 11.0485 15.4219 0 0 10.5804 10.428 10.6331 A2PYH4 HFM1_HUMAN Probable ATP-dependent DNA helicase HFM1 (EC 3.6.4.12) (SEC63 domain-containing protein 1) HFM1 SEC3D1 Homo sapiens (Human) resolution of meiotic recombination intermediates [GO:0000712] nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA helicase activity [GO:0003678]; nucleic acid binding [GO:0003676] 0.96754 -3.7486 FGPIGLNCK 0 0 0 0 0 0 0 0 0 0 12.3155 0 10.1032 10.0898 0 0 0 10.092 0 0 9.89948 0 0 0 0 0 10.7912 A2RRD8 ZN320_HUMAN Zinc finger protein 320 ZNF320 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96792 -2.8879 HDSHLAK 0 0 0 0 0 0 0 0 0 11.0305 0 0 0 0 0 0 0 0 0 0 8.30264 0 9.06267 0 7.80542 0 0 A2RRH5 WDR27_HUMAN WD repeat-containing protein 27 WDR27 Homo sapiens (Human) nucleoplasm [GO:0005654] 0.92398 -0.99648 LQLFLAE 0 0 0 0 0 0 0 0 9.96809 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A2RRP1 NBAS_HUMAN NBAS subunit of NRZ tethering complex (Neuroblastoma-amplified gene protein) (Neuroblastoma-amplified sequence) NBAS NAG Homo sapiens (Human) "negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process [GO:0000956]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]" cytosol [GO:0005829]; Dsl1/NZR complex [GO:0070939]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] SNARE binding [GO:0000149] 0.95979 -1.8257 AASMHCQELMATGYPK 0 0 0 10.3383 0 9.63303 0 0 0 0 0 0 0 0 0 14.9958 11.1013 11.2505 0 0 0 0 0 0 0 0 9.93852 A2RTX5 SYTC2_HUMAN "Threonine--tRNA ligase 2, cytoplasmic (EC 6.1.1.3) (Threonyl-tRNA synthetase) (ThrRS) (Threonyl-tRNA synthetase protein 3)" TARS3 TARSL2 Homo sapiens (Human) threonyl-tRNA aminoacylation [GO:0006435] cytoplasm [GO:0005737]; nucleus [GO:0005634] ATP binding [GO:0005524]; identical protein binding [GO:0042802]; threonine-tRNA ligase activity [GO:0004829] 0.92659 -1.2075 LKLFEILK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.86316 0 0 A2RTY3 HEAT9_HUMAN Protein HEATR9 (HEAT repeat-containing protein 9) HEATR9 C17orf66 Homo sapiens (Human) hematopoietic progenitor cell differentiation [GO:0002244] 0.69869 0.37376 QAVAQTVEELK 9.20464 0 9.04911 0 0 0 0 0 9.26409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A2RU30 TESP1_HUMAN Protein TESPA1 (Thymocyte-expressed positive selection-associated protein 1) TESPA1 KIAA0748 HSPC257 Homo sapiens (Human) COP9 signalosome assembly [GO:0010387]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of T cell receptor signaling pathway [GO:0050862]; protein localization [GO:0008104]; T cell differentiation in thymus [GO:0033077]; TCR signalosome assembly [GO:0036399] COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; TCR signalosome [GO:0036398] phospholipase binding [GO:0043274]; signaling receptor binding [GO:0005102] 0.95885 -1.7143 ILSREPEPQSPR 0 0 0 0 0 0 0 0 9.79578 0 8.58609 0 0 0 0 0 0 0 0 11.5413 11.8019 11.5768 11.163 11.5133 0 0 0 A2RU54 HMX2_HUMAN Homeobox protein HMX2 (Homeobox protein H6 family member 2) HMX2 Homo sapiens (Human) "brain development [GO:0007420]; cell differentiation [GO:0030154]; epithelial cell proliferation [GO:0050673]; inner ear morphogenesis [GO:0042472]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of stem cell proliferation [GO:2000648]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell proliferation [GO:0072089]" chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.88467 -0.12811 TVFSRSQVYQLESTFDMKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.27517 0 A2RUB1 MEIOC_HUMAN Meiosis-specific coiled-coil domain-containing protein MEIOC (Meiosis-specific with coiled-coil domain protein) MEIOC C17orf104 Homo sapiens (Human) "chromosome organization involved in meiotic cell cycle [GO:0070192]; double-strand break repair [GO:0006302]; female meiosis I [GO:0007144]; germline cell cycle switching, mitotic to meiotic cell cycle [GO:0051729]; male meiosis I [GO:0007141]; metaphase plate congression [GO:0051310]; mRNA stabilization [GO:0048255]; oocyte development [GO:0048599]; spermatid development [GO:0007286]; synaptonemal complex assembly [GO:0007130]" cytoplasm [GO:0005737]; nucleus [GO:0005634] 0.88874 -0.41233 IDELHHGFTGLDLEEQWMYPSR 0 8.96295 0 0 0 12.1325 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A2RUB6 CCD66_HUMAN Coiled-coil domain-containing protein 66 CCDC66 Homo sapiens (Human) cilium assembly [GO:0060271]; detection of light stimulus involved in visual perception [GO:0050908]; microtubule bundle formation [GO:0001578]; regulation of protein localization to cilium [GO:1903564]; retina homeostasis [GO:0001895] cell junction [GO:0030054]; centriolar satellite [GO:0034451]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cilium [GO:0005929]; cytosol [GO:0005829]; Flemming body [GO:0090543]; microtubule [GO:0005874]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750] microtubule binding [GO:0008017]; protein homodimerization activity [GO:0042803] 0.96807 -2.7541 EVSEKWNDPWK 0 0 0 0 0 0 0 0 0 9.63403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A2RUR9 C144A_HUMAN Coiled-coil domain-containing protein 144A CCDC144A KIAA0565 Homo sapiens (Human) 0.96946 -6.4863 DLSQTQCQK 0 12.2875 0 0 0 0 10.7855 0 0 0 0 10.4928 0 0 9.92064 0 0 0 0 0 0 0 0 0 0 0 0 A2RUT3 TMM89_HUMAN Transmembrane protein 89 TMEM89 Homo sapiens (Human) membrane [GO:0016020]; nucleus [GO:0005634] 0.67312 0.39371 GTSTQSG 0 0 0 0 0 0 0 0 0 0 0 8.28202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A2VCK2 DCD2B_HUMAN Doublecortin domain-containing protein 2B DCDC2B Homo sapiens (Human) intracellular signal transduction [GO:0035556] microtubule [GO:0005874]; microtubule organizing center [GO:0005815] 0.2988 0.80949 GKDPGGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.66023 0 0 0 0 0 0 0 9.48692 0 9.68096 A2VDJ0 T131L_HUMAN Transmembrane protein 131-like TMEM131L KIAA0922 Homo sapiens (Human) negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; Wnt signaling pathway [GO:0016055] cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; plasma membrane [GO:0005886] 0.96989 -3.3017 KTTHTPTLK 0 0 0 0 0 0 0 0 0 0 0 0 9.11437 0 0 0 0 10.5113 0 9.97943 0 0 0 0 0 0 0 A2VEC9 SSPO_HUMAN SCO-spondin (SCO-spondin pseudogene) SSPOP KIAA2036 SSPO Homo sapiens (Human) cell adhesion [GO:0007155] extracellular matrix [GO:0031012]; extracellular space [GO:0005615] peptidase inhibitor activity [GO:0030414] 0.96916 -4.853 EAGCPAGRLYR 0 0 0 0 0 9.24098 0 0 0 0 0 0 0 9.78311 0 0 11.6063 11.4637 9.13242 8.93746 0 0 9.65354 0 0 0 0 A3KMH1 VWA8_HUMAN von Willebrand factor A domain-containing protein 8 (PEX7-binding protein 2) (P7BP2) VWA8 KIAA0564 Homo sapiens (Human) cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; peroxisome [GO:0005777] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887] 0.0079576 2.0577 EVEYIALSR 0 0 0 0 0 0 0 0 0 9.12428 0 0 10.7311 0 9.75256 0 0 0 0 0 0 0 10.4971 0 0 0 10.2774 A3KN83 SBNO1_HUMAN Protein strawberry notch homolog 1 (Monocyte protein 3) (MOP-3) SBNO1 MOP3 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] chromatin DNA binding [GO:0031490]; histone binding [GO:0042393] 0.9237 -1.0717 DLSRFNFDNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.54477 0 0 0 0 A4D0V7 CPED1_HUMAN Cadherin-like and PC-esterase domain-containing protein 1 CPED1 C7orf58 UNQ9432/PRO34713 Homo sapiens (Human) endoplasmic reticulum [GO:0005783] 0.88163 -0.30634 AAVPQIKNENK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.62602 0 0 9.89939 A4D0Y5 CG077_HUMAN Uncharacterized protein encoded by LINC03043 (Long intergenic non-protein coding RNA 3043) LINC03043 C7orf77 Homo sapiens (Human) 0.95609 -1.5496 MGAERVCTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3309 A4D1E1 Z804B_HUMAN Zinc finger protein 804B ZNF804B Homo sapiens (Human) nucleus [GO:0005634] metal ion binding [GO:0046872] 0.96952 -6.3431 FNGNSRGNLLCFHKR 0 8.99783 10.7012 0 0 0 0 0 0 11.7727 0 10.0056 0 0 10.8715 11.4806 11.4399 0 0 0 0 0 9.11886 0 0 0 0 A4D1E9 GTPBA_HUMAN GTP-binding protein 10 (Protein obg homolog 2) (ObgH2) GTPBP10 OBGH2 UG0751c10 Homo sapiens (Human) ribosome biogenesis [GO:0042254] chromosome [GO:0005694]; mitochondrion [GO:0005739]; nucleolus [GO:0005730] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723] 0.67355 0.39371 LGGEGGK 0 0 0 0 0 0 0 0 0 0 0 8.45783 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A4D1F6 LRRD1_HUMAN Leucine-rich repeat and death domain-containing protein 1 LRRD1 Homo sapiens (Human) signal transduction [GO:0007165] 0.76016 0.29195 ISSDICNLK 0 0 0 0 0 0 0 0 0 0 0 11.568 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1039 A4D1P6 WDR91_HUMAN WD repeat-containing protein 91 WDR91 HSPC049 Homo sapiens (Human) early endosome to late endosome transport [GO:0045022]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; regulation of protein catabolic process [GO:0042176] cytosol [GO:0005829]; early endosome membrane [GO:0031901]; extrinsic component of endosome membrane [GO:0031313]; late endosome membrane [GO:0031902] phosphatidylinositol 3-kinase regulator activity [GO:0035014] 0.88969 -0.45425 DPTSGAK 0 0 0 0 0 8.66679 0 7.66377 0 0 0 9.86549 0 0 0 0 9.24453 10.6472 0 0 0 0 0 0 0 0 0 A4D1S5 RAB19_HUMAN Ras-related protein Rab-19 RAB19 RAB19B Homo sapiens (Human) autophagosome assembly [GO:0000045]; intracellular protein transport [GO:0006886] endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.91518 -0.79606 SLDIDGKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.51536 A4D1T9 PRS37_HUMAN Probable inactive serine protease 37 (Probable inactive trypsin-X2) PRSS37 TRYX2 Homo sapiens (Human) binding of sperm to zona pellucida [GO:0007339]; cell migration [GO:0016477]; germ cell migration [GO:0008354]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of fertilization [GO:1905516]; protein maturation [GO:0051604]; proteolysis [GO:0006508]; regulation of protein processing [GO:0070613] acrosomal vesicle [GO:0001669]; extracellular region [GO:0005576]; nucleus [GO:0005634] serine-type endopeptidase activity [GO:0004252] 0.95404 -1.5332 NSLCVKFVK 0 0 9.053 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A4D1U4 DEN11_HUMAN DENN domain-containing protein 11 (DENND11) (Protein LCHN) DENND11 KIAA1147 LCHN Homo sapiens (Human) cytoplasm [GO:0005737] guanyl-nucleotide exchange factor activity [GO:0005085] 0.87383 0.023424 VEQGDAAPLLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2567 0 0 A4D1Z8 GRIFN_HUMAN Grifin (Galectin-related inter-fiber protein) GRIFIN Homo sapiens (Human) carbohydrate binding [GO:0030246] 0.84824 0.15775 VLQFPCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0014 0 0 9.77591 0 0 0 0 0 A4D250 BLACE_HUMAN B-cell acute lymphoblastic leukemia-expressed protein BLACE Homo sapiens (Human) 0.95431 -1.5111 DTPPPVTSPRGDGICVSR 0 0 8.5904 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A4D263 SPT48_HUMAN Spermatogenesis-associated protein 48 SPATA48 C7orf72 Homo sapiens (Human) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] 0.56406 0.49603 EVPDISIR 0 0 0 0 0 0 0 0 0 11.2668 0 0 0 8.30072 9.10061 0 0 0 0 0 0 0 0 0 0 0 0 A4D2B8 PM2P1_HUMAN Putative postmeiotic segregation increased 2-like protein 1 (PMS2-related protein 2) (Postmeiotic segregation increased 2-like protein 13) (Postmeiotic segregation increased 2-like protein 6) (Postmeiotic segregation increased 2-like protein 8) (Postmeiotic segregation increased protein 3) (hPMS3) (Postmeiotic segregation increased protein 8) (Putative postmeiotic segregation increased 2 pseudogene 1) PMS2P1 PMS2L1 PMS2L13 PMS2L6 PMS2L8 PMS3 PMS8 PMSR2 Homo sapiens (Human) mismatch repair [GO:0006298]; phosphorylation [GO:0016310] mismatch repair complex [GO:0032300] ATP hydrolysis activity [GO:0016887]; ATP-dependent DNA damage sensor activity [GO:0140664]; kinase activity [GO:0016301] 0.88221 -0.094554 ACFPFAFCR 0 0 0 0 0 0 0 0 9.27046 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A4D2G3 O2A25_HUMAN Olfactory receptor 2A25 (Olfactory receptor 2A27) OR2A25 OR2A25P OR2A27 Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of smell [GO:0050911] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; odorant binding [GO:0005549]; olfactory receptor activity [GO:0004984] 0.87001 0.051984 YVAICHPLRYSTIMTWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.74863 0 0 0 0 0 0 0 0 0 0 0 A4D2P6 GRD2I_HUMAN "Delphilin (Glutamate receptor, ionotropic, delta 2-interacting protein 1)" GRID2IP Homo sapiens (Human) long-term synaptic depression [GO:0060292]; regulation of postsynaptic cytosolic calcium ion concentration [GO:0099566]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072] "cerebellar granule cell to Purkinje cell synapse [GO:0150048]; parallel fiber to Purkinje cell synapse [GO:0098688]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic membrane [GO:0045211]" 0.86733 0.072908 QVLMSMEPR 0 0 0 0 0 0 8.85857 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6838 0 9.74357 0 A4FU01 MTMRB_HUMAN Myotubularin-related protein 11 (Cisplatin resistance-associated protein) (hCRA) (Inactive phosphatidylinositol 3-phosphatase 11) MTMR11 Homo sapiens (Human) cytoplasm [GO:0005737]; extracellular exosome [GO:0070062] 0.68842 0.38692 VPDTLTFLR 0 13.9089 14.3727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.0846 0 0 0 0 0 0 0 0 0 A4FU49 SH321_HUMAN SH3 domain-containing protein 21 SH3D21 C1orf113 Homo sapiens (Human) actin filament organization [GO:0007015]; cell migration [GO:0016477] nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] 0.56651 0.49201 LTDIWEELK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.82653 0 0 0 0 0 0 0 A4FU69 EFCB5_HUMAN EF-hand calcium-binding domain-containing protein 5 EFCAB5 Homo sapiens (Human) calcium ion binding [GO:0005509] 0.96196 -2.0379 ISIEEQQQGK 0 0 10.2543 0 0 0 0 0 0 0 0 0 10.4801 0 0 0 0 9.62117 0 0 11.6301 0 0 8.59134 0 0 0 A4GXA9 EME2_HUMAN Probable crossover junction endonuclease EME2 (EC 3.1.22.-) EME2 Homo sapiens (Human) double-strand break repair [GO:0006302]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; replication fork processing [GO:0031297]; resolution of meiotic recombination intermediates [GO:0000712] endodeoxyribonuclease complex [GO:1905347]; Holliday junction resolvase complex [GO:0048476]; nuclear replication fork [GO:0043596] DNA binding [GO:0003677]; endonuclease activity [GO:0004519] 0.84816 0.17115 AAAEALR 0 0 0 0 0 0 0 0 0 10.3351 10.6223 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A4UGR9 XIRP2_HUMAN Xin actin-binding repeat-containing protein 2 (Beta-xin) (Cardiomyopathy-associated protein 3) (Xeplin) XIRP2 CMYA3 Homo sapiens (Human) actin filament organization [GO:0007015]; cardiac muscle tissue morphogenesis [GO:0055008]; cell-cell junction organization [GO:0045216]; ventricular septum development [GO:0003281] anchoring junction [GO:0070161]; Z disc [GO:0030018] actin filament binding [GO:0051015]; alpha-actinin binding [GO:0051393] 0.96879 -11.081 EIKGNVKR 10.4671 10.9318 9.83406 12.266 11.2245 9.30367 10.1364 12.5843 9.90961 0 11.1608 0 11.6187 9.65399 9.47551 0 0 9.07178 0 9.24752 11.0906 9.1206 9.45059 0 0 0 0 A5A3E0 POTEF_HUMAN POTE ankyrin domain family member F (ANKRD26-like family C member 1B) (Chimeric POTE-actin protein) POTEF A26C1B Homo sapiens (Human) cell motility [GO:0048870]; retina homeostasis [GO:0001895] blood microparticle [GO:0072562]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; NuA4 histone acetyltransferase complex [GO:0035267]; synapse [GO:0045202] protein kinase binding [GO:0019901]; structural constituent of postsynaptic actin cytoskeleton [GO:0098973] 0.96962 -3.1186 AGFAGDDAPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.83966 0 0 0 9.09714 0 0 0 0 0 0 A5D8V7 ODAD3_HUMAN Outer dynein arm-docking complex subunit 3 (Coiled-coil domain-containing protein 151) ODAD3 CCDC151 Homo sapiens (Human) brain development [GO:0007420]; cerebrospinal fluid circulation [GO:0090660]; cilium movement [GO:0003341]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; flagellated sperm motility [GO:0030317]; multicellular organism growth [GO:0035264]; outer dynein arm assembly [GO:0036158]; regulation of cilium assembly [GO:1902017]; spermatogenesis [GO:0007283] axoneme [GO:0005930]; centriole [GO:0005814]; ciliary basal body [GO:0036064]; ciliary rootlet [GO:0035253]; ciliary tip [GO:0097542]; cilium [GO:0005929]; extracellular region [GO:0005576]; outer dynein arm docking complex [GO:0120228] 0.95528 -1.521 GKGTAQAWTPGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0643 0 0 0 A5D8W1 CFA69_HUMAN Cilia- and flagella-associated protein 69 CFAP69 C7orf63 Homo sapiens (Human) flagellated sperm motility [GO:0030317]; olfactory behavior [GO:0042048]; positive regulation of fertilization [GO:1905516]; positive regulation of flagellated sperm motility [GO:1902093]; response to odorant [GO:1990834]; sensory perception of smell [GO:0007608]; sperm axoneme assembly [GO:0007288] cytoplasm [GO:0005737]; non-motile cilium [GO:0097730]; sperm midpiece [GO:0097225] 0.96745 -3.7494 AVVYLEDETVNK 8.52093 8.47342 0 9.94875 0 9.97413 9.4488 0 0 0 0 0 9.06296 12.2097 0 8.51846 0 0 8.63731 0 0 0 0 0 10.2655 0 0 A5PKW4 PSD1_HUMAN PH and SEC7 domain-containing protein 1 (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Exchange factor for ARF6) (Exchange factor for ARF6 A) (Pleckstrin homology and SEC7 domain-containing protein 1) PSD EFA6 EFA6A KIAA2011 PSD1 TYL Homo sapiens (Human) neuron projection development [GO:0031175]; regulation of ARF protein signal transduction [GO:0032012]; signal transduction [GO:0007165] "cleavage furrow [GO:0032154]; dendritic spine [GO:0043197]; postsynaptic density, intracellular component [GO:0099092]; ruffle membrane [GO:0032587]" guanyl-nucleotide exchange factor activity [GO:0005085]; phospholipid binding [GO:0005543] 0.47247 0.62818 EVSSHAQR 0 0 0 0 0 0 0 8.98413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.82197 A5PL33 KRBA1_HUMAN Protein KRBA1 KRBA1 KIAA1862 Homo sapiens (Human) 0.9668 -2.8407 AGDLQGLSRGTAR 0 0 0 0 0 0 0 10.6306 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A5PLK6 RGSL_HUMAN Regulator of G-protein signaling protein-like RGSL1 RGSL RGSL2 Homo sapiens (Human) membrane [GO:0016020] 0.9684 -2.7774 APKIDFKMEIIK 0 0 0 0 0 0 0 0 0 9.5109 0 0 0 0 10.0073 0 0 0 0 0 0 0 0 0 11.2798 10.3619 0 A5YKK6 CNOT1_HUMAN CCR4-NOT transcription complex subunit 1 (CCR4-associated factor 1) (Negative regulator of transcription subunit 1 homolog) (NOT1H) (hNOT1) CNOT1 CDC39 KIAA1007 NOT1 AD-005 Homo sapiens (Human) "miRNA-mediated gene silencing [GO:0035195]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of retinoic acid receptor signaling pathway [GO:0048387]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; regulation of stem cell population maintenance [GO:2000036]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; trophectodermal cell differentiation [GO:0001829]" CCR4-NOT complex [GO:0030014]; CCR4-NOT core complex [GO:0030015]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleus [GO:0005634]; P-body [GO:0000932]; peroxisomal membrane [GO:0005778] armadillo repeat domain binding [GO:0070016]; molecular adaptor activity [GO:0060090]; nuclear estrogen receptor binding [GO:0030331]; nuclear retinoic acid receptor binding [GO:0042974]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723] 0.56098 0.51544 FEIEVLCK 8.92279 0 10.5662 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7754 9.96867 0 0 0 0 0 A6H8Y1 BDP1_HUMAN Transcription factor TFIIIB component B'' homolog (Transcription factor IIIB 150) (TFIIIB150) (Transcription factor-like nuclear regulator) BDP1 KIAA1241 KIAA1689 TFNR Homo sapiens (Human) RNA polymerase III preinitiation complex assembly [GO:0070898] nucleoplasm [GO:0005654]; transcription factor TFIIIB complex [GO:0000126] TFIIIC-class transcription factor complex binding [GO:0001156] 0.96269 -2.5339 DLEETGRR 12.6932 12.4897 12.3825 10.2589 0 10.3028 11.9021 12.2163 11.9957 8.63833 0 10.3951 0 9.11155 0 10.6729 8.43596 0 0 0 0 9.96171 9.93777 9.95471 0 0 0 A6NC57 ANR62_HUMAN Ankyrin repeat domain-containing protein 62 ANKRD62 Homo sapiens (Human) 0.96944 -4.9274 CRLAAALCDHDQR 0 0 0 0 0 0 8.74329 10.4032 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NC97 F172B_HUMAN Putative protein FAM172B (FAM172B pseudogene) FAM172BP FAM172B Homo sapiens (Human) small ncRNA-mediated heterochromatin formation [GO:0031048] membrane [GO:0016020]; nucleus [GO:0005634] 0.085878 1.2248 MTQELSFQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.97398 0 0 0 0 0 0 A6NC98 CC88B_HUMAN Coiled-coil domain-containing protein 88B (Brain leucine zipper domain-containing protein) (Gipie) (Hook-related protein 3) (HkRP3) CCDC88B BRLZ Homo sapiens (Human) cytoplasmic microtubule organization [GO:0031122]; cytoskeleton-dependent intracellular transport [GO:0030705]; defense response to protozoan [GO:0042832]; positive regulation of cytokine production [GO:0001819]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102] centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleoplasm [GO:0005654] dynein light intermediate chain binding [GO:0051959]; microtubule binding [GO:0008017] 0.96783 -3.688 AQLEMQSQQLR 9.12913 0 16.7478 0 0 0 0 0 0 9.3127 0 10.7124 0 14.6342 0 0 0 0 0 0 0 11.2734 0 0 0 0 0 A6NCF6 MA13P_HUMAN Putative MAGE domain-containing protein MAGEA13P MAGEA13P Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] 0.89836 -0.66673 DFIYGEPRK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.59048 10.0749 0 0 0 0 9.44398 0 0 0 0 0 0 0 A6NCI4 VWA3A_HUMAN von Willebrand factor A domain-containing protein 3A VWA3A Homo sapiens (Human) extracellular region [GO:0005576] 0.92271 -1.0554 LCPPRPTVPLGARMSIK 10.9524 0 0 0 10.5408 10.1157 0 10.3395 10.421 0 11.3164 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NCI8 CB078_HUMAN Uncharacterized protein C2orf78 C2orf78 Homo sapiens (Human) 0.9198 -0.92748 KAQQERENAAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.84375 0 0 0 10.4084 0 0 A6NCJ1 TKTI1_HUMAN Tektin bundle-interacting protein 1 TEKTIP1 C19orf71 Homo sapiens (Human) axonemal microtubule [GO:0005879] 0.93273 -1.2648 QATRWKYTPMGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4277 0 0 A6NCL1 GEMC1_HUMAN Geminin coiled-coil domain-containing protein 1 GMNC GEMC1 Homo sapiens (Human) cell cycle [GO:0007049]; cilium assembly [GO:0060271]; DNA replication [GO:0006260]; negative regulation of DNA replication [GO:0008156] nucleus [GO:0005634] chromatin binding [GO:0003682] 0.91664 -0.83854 KLLSSDEFSKAYGK 0 0 10.487 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NCL2 LRCL1_HUMAN Leucine-rich colipase-like protein 1 LRCOL1 Homo sapiens (Human) digestion [GO:0007586]; lipid catabolic process [GO:0016042] extracellular region [GO:0005576] enzyme activator activity [GO:0008047] 0.9147 -0.79606 GIGEPCRR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.44628 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NCM1 IQCAL_HUMAN IQ and AAA domain-containing protein 1-like (IQ and AAA domain-containing protein 1 pseudogene 1) IQCA1L IQCA1P1 Homo sapiens (Human) ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; microtubule severing ATPase activity [GO:0008568] 0.96999 -3.2573 LAVDKEEERPLRAPK 0 0 9.67449 0 0 0 0 9.88859 9.82963 10.2024 0 0 0 0 8.79185 0 0 0 0 0 0 0 0 0 0 0 0 A6NCN2 KR87P_HUMAN "Putative keratin-87 protein (Keratin, hair, basic pseudogene 4) (Keratin-121 pseudogene)" KRT87P KRT121P KRTHBP4 Homo sapiens (Human) cytosol [GO:0005829]; extracellular space [GO:0005615]; keratin filament [GO:0045095] 0.65597 0.39526 AKQDMACLIR 9.08044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NCQ9 RN222_HUMAN RING finger protein 222 RNF222 Homo sapiens (Human) membrane [GO:0016020] metal ion binding [GO:0046872] 0.80334 0.24036 TLVCPICR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6876 0 0 A6NCW0 U17L3_HUMAN Ubiquitin carboxyl-terminal hydrolase 17-like protein 3 (EC 3.4.19.12) (Deubiquitinating enzyme 17-like protein 3) (Ubiquitin thioesterase 17-like protein 3) (Ubiquitin-specific-processing protease 17-like protein 3) USP17L3 USP17B USP17F Homo sapiens (Human) apoptotic process [GO:0006915]; protein deubiquitination [GO:0016579]; regulation of apoptotic process [GO:0042981]; ubiquitin-dependent protein catabolic process [GO:0006511] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634] cysteine-type deubiquitinase activity [GO:0004843]; cysteine-type endopeptidase activity [GO:0004197] 0.96997 -3.2991 FLQEQNK 0 10.587 0 0 0 0 0 0 17.1488 0 0 0 0 0 0 0 0 0 9.68278 9.99393 10.724 0 0 0 0 9.14045 0 A6ND01 JUNO_HUMAN Sperm-egg fusion protein Juno (Folate receptor 4) (Folate receptor delta) (FR-delta) (IZUMO1 receptor protein JUNO) IZUMO1R FOLR4 JUNO Homo sapiens (Human) cell adhesion [GO:0007155]; fusion of sperm to egg plasma membrane involved in single fertilization [GO:0007342]; single fertilization [GO:0007338]; sperm-egg recognition [GO:0035036] extracellular region [GO:0005576]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886] signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102] 0.95901 -1.7161 NSGRCLQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.27715 0 0 0 0 0 0 A6ND36 FA83G_HUMAN Protein FAM83G (Protein associated with SMAD1) FAM83G PAWS1 Homo sapiens (Human) BMP signaling pathway [GO:0030509] cytosol [GO:0005829]; nucleus [GO:0005634] protein kinase binding [GO:0019901] 0.76427 0.28137 DFLSELELK 0 0 0 0 0 0 0 0 0 10.5534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5314 A6NDB9 PALM3_HUMAN Paralemmin-3 PALM3 Homo sapiens (Human) negative regulation of cytokine-mediated signaling pathway [GO:0001960]; regulation of cell shape [GO:0008360]; response to lipopolysaccharide [GO:0032496]; Toll signaling pathway [GO:0008063] cytoplasm [GO:0005737]; plasma membrane [GO:0005886] ATP binding [GO:0005524] 0.96771 -2.95 DEAEMSPVVERK 0 0 9.00692 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2951 0 0 0 0 0 0 9.87066 0 0 A6NDG6 PGP_HUMAN Glycerol-3-phosphate phosphatase (G3PP) (EC 3.1.3.21) (Aspartate-based ubiquitous Mg(2+)-dependent phosphatase) (AUM) (EC 3.1.3.48) (Phosphoglycolate phosphatase) (PGP) PGP Homo sapiens (Human) glycerol biosynthetic process [GO:0006114]; glycerophospholipid metabolic process [GO:0006650]; negative regulation of gluconeogenesis [GO:0045721] cytoplasm [GO:0005737] ADP phosphatase activity [GO:0043262]; glycerol-1-phosphatase activity [GO:0000121]; glycerol-3-phosphatase activity [GO:0043136]; magnesium ion binding [GO:0000287]; phosphoglycolate phosphatase activity [GO:0008967]; protein tyrosine phosphatase activity [GO:0004725] 0.96726 -2.3394 LDTDILLGATCGLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4041 0 0 0 0 0 0 0 0 0 A6NDR6 ME3L1_HUMAN Putative homeobox protein Meis3-like 1 MEIS3P1 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; embryonic pattern specification [GO:0009880]; eye development [GO:0001654]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of transcription by RNA polymerase II [GO:0045944] nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.42263 0.66536 AWLFQHLSHPYPSEEQKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9898 0 0 0 0 0 0 0 0 0 0 0 0 A6NDX5 ZN840_HUMAN Putative zinc finger protein 840 (Zinc finger protein 840 pseudogene) ZNF840P C20orf157 ZNF840 Homo sapiens (Human) nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96841 -3.6366 APNCLSSSMQLPHGGGR 0 0 0 0 0 0 0 0 0 10.4515 0 8.6115 0 12.6557 0 0 0 0 0 0 0 0 0 0 10.7042 0 0 A6NDY0 EPAB2_HUMAN Embryonic polyadenylate-binding protein 2 (Embryonic poly(A)-binding protein 2) (ePABP-2) (ePABP2) (Embryonic poly(A)-binding protein type II) (Poly(A)-binding protein nuclear-like 1) PABPN1L EPABP2 PABPNL1 Homo sapiens (Human) "nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]" cytoplasm [GO:0005737]; nucleus [GO:0005634] poly(A) binding [GO:0008143] 0.84247 0.14597 GAPFPHSGLQGRPR 10.4105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NE01 F186A_HUMAN Protein FAM186A FAM186A Homo sapiens (Human) 0.9697 -4.02 AEAEKLGIIK 9.01246 0 0 0 0 11.4922 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NE52 WDR97_HUMAN WD repeat-containing protein 97 WDR97 KIAA1875 Homo sapiens (Human) 0.4395 0.64762 VLSETLK 0 0 0 0 0 0 0 0 16.6161 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NEC2 PSAL_HUMAN Puromycin-sensitive aminopeptidase-like protein (EC 3.4.11.-) NPEPPSL1 Homo sapiens (Human) peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062] metalloaminopeptidase activity [GO:0070006]; peptide binding [GO:0042277]; zinc ion binding [GO:0008270] 0.95593 -1.5884 AIKATFDISLVVPK 0 0 0 0 0 0 0 0 0 0 0 0 8.95684 9.03719 8.94026 0 0 0 0 0 0 0 0 0 0 0 0 A6NED2 RCCD1_HUMAN RCC1 domain-containing protein 1 RCCD1 Homo sapiens (Human) chromatin organization [GO:0006325] chromosome [GO:0005694]; cytosol [GO:0005829]; plasma membrane [GO:0005886] 0.73747 0.32495 AGPGPEALLQVWAAESALR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.87848 0 0 0 0 A6NEE1 PLHD1_HUMAN Pleckstrin homology domain-containing family D member 1 (PH domain-containing family D member 1) PLEKHD1 Homo sapiens (Human) 0.89859 -0.60503 EEPSMPYAMK 0 11.6841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1124 0 A6NEL2 SWAHB_HUMAN Ankyrin repeat domain-containing protein SOWAHB (Ankyrin repeat domain-containing protein 56) (Protein sosondowah homolog B) SOWAHB ANKRD56 Homo sapiens (Human) 0 2.8257 AADAACNGLPGSDSRR 0 8.8857 0 0 0 0 0 0 0 13.15 13.7796 0 9.76215 10.0025 10.2367 10.0304 9.7698 9.67601 0 0 0 0 0 0 0 0 0 A6NEM1 GG6L9_HUMAN Golgin subfamily A member 6-like protein 9 GOLGA6L9 GOLGA6L20 Homo sapiens (Human) 0.94794 -1.3623 EQEERLCEQEKLPGQER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.87107 9.59434 0 0 0 0 0 0 0 0 0 A6NES4 MRO2A_HUMAN Maestro heat-like repeat-containing protein family member 2A (HEAT repeat-containing protein 7B1) MROH2A HEATR7B1 Homo sapiens (Human) cytoplasm [GO:0005737] 0.96841 -3.9143 FYQRDLEER 0 0 0 0 0 0 0 0 0 0 0 11.4714 0 0 0 0 0 0 0 0 10.1581 0 0 0 0 0 0 A6NF34 ANTRL_HUMAN Anthrax toxin receptor-like ANTXRL Homo sapiens (Human) toxin transport [GO:1901998] membrane [GO:0016020] metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888] 0.87151 0.034972 IVPDGHTFMQAGFR 0 0 0 0 0 0 8.52536 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NF36 CC182_HUMAN Coiled-coil domain-containing protein 182 CCDC182 Homo sapiens (Human) female gonad development [GO:0008585] 0.73047 0.33499 QRLREEEDR 0 0 0 0 0 0 0 0 0 0 0 0 9.11072 0 0 0 0 0 0 0 0 0 9.74562 0 0 0 0 A6NFE2 SMCO2_HUMAN Single-pass membrane and coiled-coil domain-containing protein 2 SMCO2 C12orf70 Homo sapiens (Human) membrane [GO:0016020] 0.82902 0.20503 NLLELCLK 0 9.48119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NFI3 ZN316_HUMAN Zinc finger protein 316 ZNF316 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]" 0.86986 0.039783 RFSQRSVLVTHQR 0 0 0 0 0 0 0 0 0 9.61774 0 0 0 0 0 0 0 0 0 0 0 9.86254 0 0 0 0 0 A6NFK2 GRCR2_HUMAN Glutaredoxin domain-containing cysteine-rich protein 2 (GRXCR1-like protein) (Glutaredoxin domain-containing cysteine-rich protein 1-like protein) GRXCR2 Homo sapiens (Human) auditory receptor cell stereocilium organization [GO:0060088]; protein localization to organelle [GO:0033365]; sensory perception of sound [GO:0007605] microvillus [GO:0005902]; stereocilium base [GO:0120044]; stereocilium shaft [GO:0120043] 0.96792 -3.7311 EESYGGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.00273 0 0 0 0 0 0 A6NFR6 CE060_HUMAN Uncharacterized protein C5orf60 C5orf60 Homo sapiens (Human) membrane [GO:0016020] 0.89765 -0.53544 EEDSENDQAEVGEWLR 0 0 0 0 0 0 0 9.59571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NFU8 PGPIL_HUMAN Pyroglutamyl-peptidase 1-like protein (EC 3.4.19.-) PGPEP1L Homo sapiens (Human) proteolysis [GO:0006508] cysteine-type peptidase activity [GO:0008234] 0.87152 0.064272 AQFEENSTMVLPAK 0 0 0 0 9.53545 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NFZ4 FA24A_HUMAN Protein FAM24A FAM24A Homo sapiens (Human) extracellular region [GO:0005576] 0.91413 -0.79612 NHNPDKVCWATNSQAK 0 0 0 0 0 0 0 0 0 0 0 0 9.5048 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NGE7 URAD_HUMAN Putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase (OHCU decarboxylase) (EC 4.1.1.97) (Parahox neighbor) (Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase) URAD PRHOXNB Homo sapiens (Human) allantoin metabolic process [GO:0000255]; purine nucleobase metabolic process [GO:0006144] peroxisome [GO:0005777] carboxy-lyase activity [GO:0016831] 0.88958 -0.4725 FSDRTAVPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.47324 A6NGG8 PCARE_HUMAN Photoreceptor cilium actin regulator PCARE C2orf71 Homo sapiens (Human) photoreceptor cell outer segment organization [GO:0035845]; protein localization to photoreceptor outer segment [GO:1903546]; response to stimulus [GO:0050896]; visual perception [GO:0007601] cilium [GO:0005929]; cone photoreceptor outer segment [GO:0120199]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750] 0.72844 0.33946 AIRPGCQGGSER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2099 A6NGH7 CC160_HUMAN Coiled-coil domain-containing protein 160 CCDC160 Homo sapiens (Human) 0.78532 0.25456 EIFTKPLNFQETETDASK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1259 0 0 0 0 0 0 0 0 0 0 0 A6NGR9 MROH6_HUMAN Maestro heat-like repeat-containing protein family member 6 MROH6 C8orf73 Homo sapiens (Human) cytoplasm [GO:0005737] 0.96977 -4.0804 LPPLLDDTRDSIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.08587 0 0 0 0 0 A6NGU5 GGT3_HUMAN Putative glutathione hydrolase 3 proenzyme (EC 3.4.19.13) (Gamma-glutamyltransferase 3) (Putative gamma-glutamyltranspeptidase 3) (GGT 3) (EC 2.3.2.2) [Cleaved into: Putative glutathione hydrolase 3 heavy chain; Putative glutathione hydrolase 3 light chain] GGT3P GGT3 Homo sapiens (Human) glutathione biosynthetic process [GO:0006750]; glutathione catabolic process [GO:0006751]; leukotriene D4 biosynthetic process [GO:1901750]; peptide modification [GO:0031179]; proteolysis [GO:0006508]; regulation of immune system process [GO:0002682]; regulation of inflammatory response [GO:0050727] extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] glutathione hydrolase activity [GO:0036374]; hypoglycin A gamma-glutamyl transpeptidase activity [GO:0102953]; leukotriene C4 gamma-glutamyl transferase activity [GO:0103068] 0.82594 0.21412 AEVINAR 0 15.2371 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.53506 0 0 0 0 0 0 0 0 0 0 A6NGU7 CX028_HUMAN Putative uncharacterized protein encoded by LINC01546 LINC01546 CXorf28 Homo sapiens (Human) 0.92045 -1.141 ATQQWILKNK 0 0 0 0 0 0 0 0 8.6537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NGW2 STRCL_HUMAN Putative stereocilin-like protein (Stereocilin pseudogene 1) STRCP1 STRCP Homo sapiens (Human) cell-matrix adhesion [GO:0007160] cell surface [GO:0009986]; extracellular region [GO:0005576]; kinocilium [GO:0060091]; stereocilium tip [GO:0032426] 0.56466 0.49433 ASQPSAHISPR 0 0 0 0 0 0 0 0 0 0 0 0 10.4406 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NGY3 CE052_HUMAN Uncharacterized protein C5orf52 C5orf52 Homo sapiens (Human) 0.76039 0.2957 ISHYYEHLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.73252 0 0 0 A6NH00 OR2T8_HUMAN Olfactory receptor 2T8 OR2T8 OR2T8P Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of smell [GO:0050911] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.91368 -0.78297 MAADYLTGSKAISR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7143 0 A6NHJ4 ZN860_HUMAN Zinc finger protein 860 ZNF860 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.94798 -1.363 AIHTGEKPYK 9.60849 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NHL2 TBAL3_HUMAN Tubulin alpha chain-like 3 (EC 3.6.5.-) TUBAL3 Homo sapiens (Human) microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] cytoplasm [GO:0005737]; microtubule [GO:0005874] GTP binding [GO:0005525]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; structural constituent of cytoskeleton [GO:0005200] 0.92301 -1.0778 AFLHWYLREGMEEAEFLEAR 0 0 0 10.0462 10.9232 0 0 9.61989 0 0 0 0 0 9.3054 0 0 0 0 0 0 0 10.0773 0 0 0 0 0 A6NHN0 OTOL1_HUMAN Otolin-1 OTOL1 Homo sapiens (Human) extracellular matrix organization [GO:0030198]; otolith mineralization [GO:0045299]; protein homooligomerization [GO:0051260] collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] calcium ion binding [GO:0005509]; extracellular matrix structural constituent [GO:0005201] 0.89956 -0.68882 GEGGMKGEKGSK 0 0 0 0 0 0 0 9.61261 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NHN6 NPB15_HUMAN Nuclear pore complex-interacting protein family member B15 (Nuclear pore complex-interacting protein-like 2) NPIPB15 NPIPL2 Homo sapiens (Human) extracellular region [GO:0005576]; nucleoplasm [GO:0005654] 0.91969 -1.1426 THAPKTN 0 0 0 0 0 7.95268 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NHQ4 EPOP_HUMAN Elongin BC and Polycomb repressive complex 2-associated protein (Proline-rich protein 28) EPOP C17orf96 PRR28 Homo sapiens (Human) neuron fate commitment [GO:0048663]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell differentiation [GO:0048863] chromosome [GO:0005694]; elongin complex [GO:0070449]; ESC/E(Z) complex [GO:0035098] chromatin binding [GO:0003682]; protein-containing complex binding [GO:0044877] 0.80095 0.23954 GTQEFSPLCLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.83202 A6NHR8 FA47D_HUMAN Putative protein FAM47D FAM47DP Homo sapiens (Human) 0.96937 -3.5524 ATYEDQQIKK 0 0 0 0 0 12.4708 0 0 0 0 0 0 8.18483 0 10.0835 0 0 0 0 0 0 0 0 0 0 0 0 A6NHR9 SMHD1_HUMAN Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMC hinge domain-containing protein 1) (EC 3.6.1.-) SMCHD1 KIAA0650 Homo sapiens (Human) chromosome organization [GO:0051276]; dosage compensation by inactivation of X chromosome [GO:0009048]; double-strand break repair [GO:0006302]; inactivation of X chromosome by heterochromatin formation [GO:0060820]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; nose development [GO:0043584]; positive regulation of DNA repair [GO:0045739]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034] Barr body [GO:0001740]; site of double-strand break [GO:0035861] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA binding [GO:0003677]; protein homodimerization activity [GO:0042803] 0.9693 -4.8315 DVAPVEK 0 0 0 0 9.3196 9.10845 0 0 0 0 0 0 0 10.0253 9.02926 0 0 0 10.2619 0 0 0 0 0 0 8.89367 0 A6NHY2 AKD1B_HUMAN Ankyrin repeat and death domain-containing protein 1B ANKDD1B Homo sapiens (Human) signal transduction [GO:0007165] 0.95387 -1.5137 AVDKQGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.60988 A6NHZ5 LR14B_HUMAN Leucine-rich repeat-containing protein 14B LRRC14B Homo sapiens (Human) cytoplasm [GO:0005737] 0.91058 -0.74832 KLEVVHNVR 0 0 0 0 9.69422 0 9.76175 9.43704 0 10.0546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NI28 RHG42_HUMAN Rho GTPase-activating protein 42 (Rho GTPase-activating protein 10-like) (Rho-type GTPase-activating protein 42) ARHGAP42 GRAF3 TMEM133 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of systemic arterial blood pressure [GO:0003085]; negative regulation of vascular associated smooth muscle contraction [GO:1904694]; signal transduction [GO:0007165] cytoplasm [GO:0005737] GTPase activator activity [GO:0005096] 0.8836 -0.2629 EQIGAAKDGKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3069 0 0 0 0 0 0 A6NI56 CC154_HUMAN Coiled-coil domain-containing protein 154 CCDC154 C16orf29 Homo sapiens (Human) bone mineralization involved in bone maturation [GO:0035630]; bone resorption [GO:0045453]; odontogenesis of dentin-containing tooth [GO:0042475]; tooth eruption [GO:0044691] early endosome [GO:0005769] 0.95734 -1.6588 ALPSLVRPRVFIK 8.72093 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NI79 CCD69_HUMAN Coiled-coil domain-containing protein 69 CCDC69 Homo sapiens (Human) spindle midzone assembly [GO:0051255] cytoplasm [GO:0005737]; midbody [GO:0030496]; nucleus [GO:0005634]; spindle midzone [GO:0051233] microtubule binding [GO:0008017] 0.96849 -3.9227 EVQLRRQLQQEK 0 0 0 0 8.84515 0 0 0 0 0 0 0 0 0 9.47618 0 0 0 0 0 0 0 0 0 0 0 0 A6NIE6 RN3P2_HUMAN Putative RRN3-like protein RRN3P2 (RNA polymerase I transcription factor homolog pseudogene 2) RRN3P2 Homo sapiens (Human) transcription initiation at RNA polymerase I promoter [GO:0006361] nucleus [GO:0005634] RNA polymerase I core binding [GO:0001042]; RNA polymerase I general transcription initiation factor activity [GO:0001181] 0.86961 0.052207 ICTIECYVHNLLR 0 0 0 9.63189 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NIJ5 F90AK_HUMAN Putative protein FAM90A20P FAM90A20P FAM90A20 Homo sapiens (Human) 0.92444 -1.1747 DPTSWAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4194 10.1157 0 0 0 A6NIK2 LR10B_HUMAN Leucine-rich repeat-containing protein 10B LRRC10B Homo sapiens (Human) 0.86759 0.070626 GLWLYGNR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.98085 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NIV6 LRIQ4_HUMAN Leucine-rich repeat and IQ domain-containing protein 4 (Leucine-rich repeat-containing protein 64) LRRIQ4 LRRC64 Homo sapiens (Human) 0.96165 -2.5922 CLPKEIVNQTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.2363 0 0 0 0 0 0 0 0 0 0 0 A6NJ64 NPIB2_HUMAN Putative nuclear pore complex-interacting protein family member B2 NPIPB2 Homo sapiens (Human) nucleoplasm [GO:0005654] 0.96797 -2.879 IIIAFPRSYK 0 0 0 0 0 0 0 10.0311 0 0 9.89028 0 9.46807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NJ69 IGIP_HUMAN IgA-inducing protein homolog IGIP C5orf53 Homo sapiens (Human) extracellular region [GO:0005576] 0.93226 -1.2865 MCSYYHMKKR 0 0 0 0 0 0 0 0 0 0 9.78414 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NJ88 SGE2P_HUMAN Putative SAGE1-like protein (Sarcoma antigen 2 pseudogene) SAGE2P Homo sapiens (Human) snRNA 3'-end processing [GO:0034472] integrator complex [GO:0032039] 0.88373 -0.27683 EIDSHCHLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.30684 0 0 0 0 0 0 0 0 A6NJB7 PRR19_HUMAN Proline-rich protein 19 PRR19 Homo sapiens (Human) meiotic cell cycle [GO:0051321] chromosome [GO:0005694]; nucleus [GO:0005634] 0.92151 -1.1317 AQEPAPRSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.68591 0 0 0 0 0 0 0 0 A6NJI9 LRC72_HUMAN Leucine-rich repeat-containing protein 72 LRRC72 Homo sapiens (Human) 0.86993 0.066381 ELTEVIDLSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.3802 0 0 0 0 0 0 A6NJJ6 CS067_HUMAN UPF0575 protein C19orf67 C19orf67 Homo sapiens (Human) 0.94015 -1.3057 FPRYLYKK 0 0 0 0 0 0 0 0 0 0 0 0 8.70736 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NJL1 ZSA5B_HUMAN Zinc finger and SCAN domain-containing protein 5B ZSCAN5B Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.91547 -0.83421 GNLNVHQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4534 0 0 0 0 0 0 A6NJT0 UNC4_HUMAN Homeobox protein unc-4 homolog (Homeobox protein Uncx4.1) UNCX UNCX4.1 Homo sapiens (Human) cartilage condensation [GO:0001502]; common myeloid progenitor cell proliferation [GO:0035726]; dorsal spinal cord development [GO:0021516]; olfactory bulb interneuron differentiation [GO:0021889]; pattern specification process [GO:0007389]; regulation of cell differentiation [GO:0045595]; regulation of gene expression [GO:0010468] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.94909 -1.3742 ELEKMEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.99393 0 0 0 0 0 0 0 A6NJZ3 O6C65_HUMAN Olfactory receptor 6C65 OR6C65 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.63558 0.39744 EGMALSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.39485 A6NK53 ZN233_HUMAN Zinc finger protein 233 ZNF233 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.91578 -0.80846 TTWDFWRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3162 0 0 0 0 A6NK58 LIPT2_HUMAN "Putative lipoyltransferase 2, mitochondrial (EC 2.3.1.181) (Lipoate-protein ligase B) (Lipoyl/octanoyl transferase) (Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase)" LIPT2 Homo sapiens (Human) carboxylic acid metabolic process [GO:0019752]; positive regulation of oxygen metabolic process [GO:2000376]; protein lipoylation [GO:0009249] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] ligase activity [GO:0016874]; lipoyl(octanoyl) transferase activity [GO:0033819] 0.83708 0.19315 ALGAEVR 0 0 0 0 0 0 0 0 0 0 0 0 9.11437 0 0 0 0 10.5113 0 0 0 0 0 0 0 0 0 A6NK89 RASFA_HUMAN Ras association domain-containing protein 10 RASSF10 Homo sapiens (Human) nervous system development [GO:0007399]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neurogenesis [GO:0050769]; signal transduction [GO:0007165] cytosol [GO:0005829]; microtubule organizing center [GO:0005815]; spindle pole [GO:0000922] 0.85002 0.11642 EIDHYEAKVHLDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2862 0 0 A6NK97 S22AK_HUMAN Solute carrier family 22 member 20 (Organic anion transporter 6) (Solute carrier family 22 member 20 pseudogene) SLC22A20P OAT6 SLC22A20 Homo sapiens (Human) monoatomic ion transport [GO:0006811] membrane [GO:0016020] transmembrane transporter activity [GO:0022857] 0.93311 -1.2653 EGSSKKHVEEK 0 0 0 0 8.84831 0 0 0 0 0 0 0 0 0 0 0 9.49887 0 0 0 0 0 0 0 0 0 0 A6NKB5 PCX2_HUMAN Pecanex-like protein 2 (Pecanex homolog protein 2) PCNX2 KIAA0435 PCNXL2 Homo sapiens (Human) membrane [GO:0016020] 0.96997 -3.3024 EVEAIMEGDEEDR 9.85295 9.97241 9.82891 0 0 0 0 0 9.7143 9.83665 0 9.85367 0 0 0 0 0 0 9.83883 0 0 0 11.5369 0 0 0 0 A6NKC9 SH2D7_HUMAN SH2 domain-containing protein 7 SH2D7 Homo sapiens (Human) cytoplasm [GO:0005737] 0.80281 0.23864 ATGYILSYR 0 0 0 0 0 0 0 0 0 0 0 10.2512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NKD9 CC85C_HUMAN Coiled-coil domain-containing protein 85C CCDC85C Homo sapiens (Human) cerebral cortex development [GO:0021987] adherens junction [GO:0005912]; apical junction complex [GO:0043296]; bicellular tight junction [GO:0005923] 0.91391 -0.82448 APDGKAGATR 0 9.71886 9.39408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NKF1 SAC31_HUMAN SAC3 domain-containing protein 1 (SAC3 homology domain-containing protein 1) SAC3D1 SHD1 Homo sapiens (Human) cell division [GO:0051301]; centrosome duplication [GO:0051298]; spindle assembly [GO:0051225] centrosome [GO:0005813]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle [GO:0005819] 0.64683 0.39623 GAGPHPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1944 0 0 0 0 0 A6NKF2 ARI3C_HUMAN AT-rich interactive domain-containing protein 3C (ARID domain-containing protein 3C) ARID3C Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] cytoplasm [GO:0005737]; membrane raft [GO:0045121]; nucleus [GO:0005634] chromatin binding [GO:0003682]; DNA binding [GO:0003677] 0.91907 -0.89532 QVLDLYALFR 0 0 0 0 0 0 0 0 0 0 8.74813 9.12472 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NKL6 T200C_HUMAN Transmembrane protein 200C (Transmembrane protein TTMA) (Two transmembrane domain-containing family member A) TMEM200C TTMA Homo sapiens (Human) membrane [GO:0016020] 0.87135 0.051134 AASPSPPLRLEGSPPTR 0 0 0 0 0 0 10.5086 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NKP2 D42E2_HUMAN Putative short-chain dehydrogenase/reductase family 42E member 2 (EC 1.1.1.-) SDR42E2 Homo sapiens (Human) steroid biosynthetic process [GO:0006694] "3-beta-hydroxy-delta5-steroid dehydrogenase activity [GO:0003854]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]" 0.96762 -2.3361 LVIDVCVRR 0 0 9.40037 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NKT7 RGPD3_HUMAN RanBP2-like and GRIP domain-containing protein 3 RGPD3 RGP3 Homo sapiens (Human) NLS-bearing protein import into nucleus [GO:0006607] cytoplasm [GO:0005737]; nuclear pore [GO:0005643] 0.96978 -4.7038 AIKEEMQELK 10.4289 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.85496 0 0 9.82804 10.1055 9.14277 0 0 0 A6NKX4 S22AV_HUMAN Putative solute carrier family 22 member 31 SLC22A31 Homo sapiens (Human) monoatomic ion transport [GO:0006811] membrane [GO:0016020] transmembrane transporter activity [GO:0022857] 0.96225 -2.5541 AAGGFGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.51767 0 0 0 8.94708 0 0 0 0 0 0 0 0 A6NL88 SHSA7_HUMAN Protein shisa-7 (Cystine-knot AMPAR modulating protein of 59 kDa) (CKAMP59) (GABA(A) receptor auxiliary subunit Shisa7) (Protein shisa-6-like) SHISA7 Homo sapiens (Human) gamma-aminobutyric acid receptor clustering [GO:0097112]; gamma-aminobutyric acid signaling pathway [GO:0007214]; memory [GO:0007613]; positive regulation of long-term synaptic potentiation [GO:1900273]; regulation of AMPA glutamate receptor clustering [GO:1904717]; regulation of AMPA receptor activity [GO:2000311]; regulation of GABA-A receptor activity [GO:0106040]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of short-term neuronal synaptic plasticity [GO:0048172] "AMPA glutamate receptor complex [GO:0032281]; asymmetric, glutamatergic, excitatory synapse [GO:0098985]; dendritic spine membrane [GO:0032591]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]" GABA receptor binding [GO:0050811]; ionotropic glutamate receptor binding [GO:0035255] 0.6535 0.39575 TGGAGGR 0 0 9.02067 0 0 0 0 0 0 9.20112 0 8.84301 0 0 0 8.54882 0 0 0 0 0 0 0 0 0 8.54411 10.8518 A6NLC5 CC070_HUMAN UPF0524 protein C3orf70 C3orf70 Homo sapiens (Human) circadian behavior [GO:0048512]; nervous system development [GO:0007399] 0.87138 0.055646 CFKLHWCCHLGWCHCK 0 0 0 0 0 0 0 0 0 0 0 0 10.4728 0 10.8187 0 10.9394 0 0 0 0 0 0 0 0 0 0 A6NLE4 SIM23_HUMAN Small integral membrane protein 23 SMIM23 C5orf50 Homo sapiens (Human) plasma membrane [GO:0005886] 0.9324 -1.2594 QVAAEQVAAQLLERRR 0 0 0 0 0 0 9.64279 0 0 0 0 0 0 0 0 0 11.1972 0 0 11.0314 0 0 0 0 0 0 0 A6NLI5 TR64C_HUMAN Tripartite motif-containing protein 64C TRIM64C Homo sapiens (Human) innate immune response [GO:0045087]; protein ubiquitination [GO:0016567]; regulation of gene expression [GO:0010468] cytoplasm [GO:0005737] ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.3225 0.78719 ELFCEADKR 0 0 0 10.2854 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.07369 0 0 0 0 0 0 A6NLW8 DUXA_HUMAN Double homeobox protein A DUXA Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]" 0.96126 -2.0012 AFMKNPYPGIDSR 9.20178 0 0 9.47348 0 0 0 0 0 0 0 0 0 0 9.65066 0 0 0 0 0 0 0 0 0 0 0 0 A6NM03 O2AG2_HUMAN Olfactory receptor 2AG2 OR2AG2 OR2AG2P Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of smell [GO:0050911] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.88836 -0.40571 ALADFLR 0 0 0 0 0 0 0 0 0 0 0 10.0247 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NM28 ZFP92_HUMAN Zinc finger protein 92 homolog (Zfp-92) ZFP92 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.95209 -1.3929 AAILLTTRPK 0 0 0 0 0 0 10.4578 0 0 0 0 0 0 0 0 0 0 0 8.85309 0 0 0 0 0 0 0 10.0891 A6NM43 TCPQL_HUMAN Putative T-complex protein 1 subunit theta-like 1 CCT8L1P CCT8L1 Homo sapiens (Human) protein folding [GO:0006457] chaperonin-containing T-complex [GO:0005832] ATP binding [GO:0005524]; ATP-dependent protein folding chaperone [GO:0140662]; unfolded protein binding [GO:0051082] 0.88532 -0.21685 KSPTHQQIWNPDSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.001 0 0 A6NM62 LRC53_HUMAN Leucine-rich repeat-containing protein 53 LRRC53 Homo sapiens (Human) plasma membrane [GO:0005886] 0.89063 -0.46577 IKGQNLKLNLHPFR 0 0 0 0 0 0 0 0 0 0 0 10.4 0 0 0 0 10.8039 0 0 0 0 0 0 0 8.93658 0 0 A6NMS7 L37A1_HUMAN Leucine-rich repeat-containing protein 37A LRRC37A LRRC37A1 Homo sapiens (Human) membrane [GO:0016020] 0.96052 -1.9888 ALTAPEEHK 0 0 0 0 0 0 0 12.7635 0 0 9.62084 0 0 9.68226 0 0 9.25241 0 0 0 0 0 9.85382 8.98391 0 0 0 A6NMX2 I4E1B_HUMAN Eukaryotic translation initiation factor 4E type 1B EIF4E1B Homo sapiens (Human) eukaryotic translation initiation factor 4F complex [GO:0016281]; mRNA cap binding complex [GO:0005845] RNA 7-methylguanosine cap binding [GO:0000340]; translation initiation factor activity [GO:0003743] 0.88151 -0.097275 WALWFFKNDRSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.46428 0 0 0 0 0 0 A6NMZ7 CO6A6_HUMAN Collagen alpha-6(VI) chain COL6A6 Homo sapiens (Human) cell adhesion [GO:0007155] collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576] 0.96705 -3.7536 GEPGDLGEK 0 9.98342 0 0 0 0 0 0 0 11.3455 11.4356 0 0 0 0 0 0 0 0 10.7233 0 0 0 0 0 0 0 A6NN14 ZN729_HUMAN Zinc finger protein 729 ZNF729 Homo sapiens (Human) nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96107 -2.0013 AIHTGEKPYK 0 0 0 0 0 0 0 0 0 0 13.6405 0 0 0 0 0 10.0017 0 0 0 0 0 0 0 0 0 0 A6NN90 CB081_HUMAN Uncharacterized protein C2orf81 C2orf81 Homo sapiens (Human) 0.76456 0.27979 WPSGWEGK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.74071 0 0 0 10.5494 0 0 0 0 0 0 0 0 0 A6NNA2 SRRM3_HUMAN Serine/arginine repetitive matrix protein 3 SRRM3 Homo sapiens (Human) nucleus [GO:0005634] mRNA binding [GO:0003729] 0.96975 -5.0116 AAGGAGR 8.78581 0 8.97945 0 0 8.47216 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.73951 0 10.0375 0 A6NNA5 DRGX_HUMAN Dorsal root ganglia homeobox protein (Paired-related homeobox protein-like 1) DRGX PRRXL1 Homo sapiens (Human) axon guidance [GO:0007411]; detection of chemical stimulus [GO:0009593]; detection of temperature stimulus [GO:0016048]; dorsal spinal cord development [GO:0021516]; neuron migration [GO:0001764]; regulation of transcription by RNA polymerase II [GO:0006357]; sensory perception of mechanical stimulus [GO:0050954]; trigeminal nerve development [GO:0021559] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96006 -1.9774 EALEAQQSLGR 0 0 0 0 0 0 0 0 0 9.79498 0 0 0 0 0 0 10.2965 0 0 0 0 0 0 0 0 0 0 A6NNC1 P12LL_HUMAN Putative POM121-like protein 1-like Homo sapiens (Human) membrane [GO:0016020] 0.9619 -2.556 AQRSEVRYNQR 9.15939 9.44398 0 0 0 0 0 0 0 0 0 8.99952 0 0 0 0 0 0 0 0 0 0 10.3289 0 0 0 0 A6NNE9 MARHB_HUMAN E3 ubiquitin-protein ligase MARCHF11 (EC 2.3.2.27) (Membrane-associated RING finger protein 11) (Membrane-associated RING-CH protein XI) (MARCH-XI) (RING-type E3 ubiquitin transferase MARCHF11) MARCHF11 MARCH11 Homo sapiens (Human) protein ubiquitination [GO:0016567] cytoplasmic vesicle membrane [GO:0030659] ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.56498 0.48665 GAGDQPETRSVCSSRSSSSGGGDQR 0 0 0 0 0 0 0 0 0 0 10.6944 11.4464 0 0 8.48796 0 0 0 0 0 0 0 0 0 0 0 0 A6NNF4 ZN726_HUMAN Zinc finger protein 726 ZNF726 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96233 -2.5081 AFIWSSNLTEHKK 0 9.35975 0 0 0 0 0 0 0 0 0 12.2377 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NNH2 F90AR_HUMAN Protein FAM90A27P FAM90A27P Homo sapiens (Human) 0.92705 -1.1943 EKERSPSPQQQQSEAPTQTFPR 0 0 0 0 11.0477 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A6NNM8 TTL13_HUMAN Tubulin polyglutamylase TTLL13 (EC 6.3.2.-) (Tubulin tyrosine ligase like 13) (Tubulin tyrosine ligase-like family member 13 pseudogene) (Tubulin--tyrosine ligase-like protein 13) TTLL13 TTLL13P Homo sapiens (Human) microtubule cytoskeleton organization [GO:0000226]; protein polyglutamylation [GO:0018095] cilium [GO:0005929]; cytosol [GO:0005829]; microtubule [GO:0005874] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; tubulin binding [GO:0015631]; tubulin-glutamic acid ligase activity [GO:0070740] 0.96877 -3.0192 ARDQNQGESAGEKSRPR 0 0 0 0 0 0 0 0 0 0 10.3846 0 0 0 0 0 0 0 0 0 9.59535 0 0 0 10.5344 0 0 A6NNT2 CP096_HUMAN Uncharacterized protein C16orf96 C16orf96 Homo sapiens (Human) 0.96188 -2.0273 DGAPKDR 0 0 0 0 0 0 0 0 0 0 0 0 8.7107 9.9714 0 0 0 0 0 0 9.97054 0 0 10.2525 10.1727 0 0 A6NNW6 ENO4_HUMAN Enolase 4 (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) ENO4 C10orf134 Homo sapiens (Human) cilium organization [GO:0044782]; flagellated sperm motility [GO:0030317]; glycolytic process [GO:0006096] phosphopyruvate hydratase complex [GO:0000015]; sperm principal piece [GO:0097228] magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634] 0.78203 0.26113 YEVIMGTYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.73471 0 0 0 0 0 0 0 0 0 0 A6PVS8 LRIQ3_HUMAN Leucine-rich repeat and IQ domain-containing protein 3 (Leucine-rich repeat-containing protein 44) LRRIQ3 LRRC44 Homo sapiens (Human) 0.96869 -3.6016 DLFFKPETNIK 9.84588 0 0 0 0 0 0 0 10.7943 0 0 0 0 0 0 10.6474 13.3299 0 0 9.57344 9.85582 0 0 0 8.39378 0 0 A6QL63 ABTB3_HUMAN Ankyrin repeat and BTB/POZ domain-containing protein 3 (BTB/POZ domain-containing protein 11) ABTB3 BTBD11 Homo sapiens (Human) SMAD protein signal transduction [GO:0060395] membrane [GO:0016020] protein heterodimerization activity [GO:0046982] 0.96885 -3.3353 GADPLIGTMYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.69003 0 A6QL64 AN36A_HUMAN Ankyrin repeat domain-containing protein 36A ANKRD36 ANKRD36A KIAA1641 UNQ2430/PRO499 Homo sapiens (Human) 0.96827 -3.6544 CELNLCDREDR 0 0 0 0 0 0 0 0 0 0 0 8.93864 0 0 9.68196 9.90588 0 0 0 0 0 0 0 0 0 11.042 0 A7E2F4 GOG8A_HUMAN Golgin subfamily A member 8A (88 kDa Golgi matrix protein) (GM88) (GM88 autoantigen) GOLGA8A KIAA0855 Homo sapiens (Human) Golgi organization [GO:0007030] cis-Golgi network [GO:0005801]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi cis cisterna [GO:0000137]; Golgi cisterna membrane [GO:0032580] 0.96922 -3.9698 DLEVGGSGRR 0 0 0 0 0 0 0 0 0 9.97585 0 11.9795 0 7.84681 0 0 0 0 0 0 0 0 0 0 0 0 0 A7E2S9 A30BL_HUMAN Putative ankyrin repeat domain-containing protein 30B-like ANKRD30BL NCRNA00164 Homo sapiens (Human) 0.51243 0.60159 LERMMKK 10.1438 0 0 0 0 0 0 10.0827 0 0 10.6831 0 0 9.99563 0 0 0 0 0 0 0 0 0 0 0 0 0 A7E2U8 CD047_HUMAN UPF0602 protein C4orf47 C4orf47 Chr4_1746 Homo sapiens (Human) 9+0 non-motile cilium [GO:0097731]; centrosome [GO:0005813]; cytoplasmic microtubule [GO:0005881] 0.72258 0.36099 KANEEHHRLLK 9.4662 8.85866 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A7E2V4 ZSWM8_HUMAN Zinc finger SWIM domain-containing protein 8 ZSWIM8 KIAA0913 Homo sapiens (Human) positive regulation of miRNA catabolic process [GO:2000627]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; target-directed miRNA degradation [GO:0140958] Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytosol [GO:0005829] ubiquitin ligase-substrate adaptor activity [GO:1990756]; zinc ion binding [GO:0008270] 0.96141 -2.5999 GLGEGVPSSQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5383 0 0 0 9.43085 0 8.75215 10.9238 0 0 0 0 0 A7E2Y1 MYH7B_HUMAN "Myosin-7B (Antigen MLAA-21) (Myosin cardiac muscle beta chain) (Myosin heavy chain 7B, cardiac muscle beta isoform) (Slow A MYH14)" MYH7B KIAA1512 Homo sapiens (Human) cytoplasm [GO:0005737]; membrane [GO:0016020]; myosin filament [GO:0032982]; myosin II complex [GO:0016460] actin filament binding [GO:0051015]; ATP binding [GO:0005524]; microfilament motor activity [GO:0000146] 0.96933 -3.3903 ANAEVAQWRSKYEADAIQR 0 0 0 0 0 0 0 0 9.51394 0 0 0 0 0 0 0 0 10.0062 10.12 0 0 0 0 0 0 0 0 A7MBM2 DISP2_HUMAN Protein dispatched homolog 2 DISP2 C15orf36 DISPB KIAA1742 LINC00594 Homo sapiens (Human) smoothened signaling pathway [GO:0007224] membrane [GO:0016020]; plasma membrane [GO:0005886] transmembrane transporter activity [GO:0022857] 0.89249 -0.51164 GASLMDIYLDR 0 0 0 0 0 0 0 0 0 0 0 0 9.48059 0 0 0 0 0 0 0 0 9.41282 0 0 0 0 0 A7MD48 SRRM4_HUMAN Serine/arginine repetitive matrix protein 4 (Medulloblastoma antigen MU-MB-2.76) (Neural-specific serine/arginine repetitive splicing factor of 100 kDa) (Neural-specific SR-related protein of 100 kDa) (nSR100) SRRM4 KIAA1853 Homo sapiens (Human) "cell differentiation [GO:0030154]; mRNA processing [GO:0006397]; nervous system development [GO:0007399]; neuron maturation [GO:0042551]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]; sensory perception of sound [GO:0007605]" nucleus [GO:0005634] identical protein binding [GO:0042802]; mRNA binding [GO:0003729] 0.95725 -1.6593 ASPRYTQSRSTSSEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.23019 0 0 0 9.84475 9.35782 0 0 9.02907 0 10.492 0 A7XYQ1 SOBP_HUMAN Sine oculis-binding protein homolog (Jackson circler protein 1) SOBP JXC1 Homo sapiens (Human) animal organ development [GO:0048513]; cochlea development [GO:0090102]; cognition [GO:0050890]; inner ear morphogenesis [GO:0042472]; locomotory behavior [GO:0007626]; sensory perception of sound [GO:0007605] nucleus [GO:0005634] metal ion binding [GO:0046872]; SUMO polymer binding [GO:0032184] 0.84085 0.17908 ENNCASNCHLDGEAAK 0 0 0 0 0 0 0 0 0 0 9.03727 9.0114 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A8K010 CF176_HUMAN Putative transcriptional regulator encoded by LINC00473 LINC00473 C6orf176 Homo sapiens (Human) DNA-templated transcription [GO:0006351] 0.96169 -2.5603 APGCAGR 0 0 0 0 0 0 0 0 0 0 8.58692 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A8K2U0 A2ML1_HUMAN Alpha-2-macroglobulin-like protein 1 (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 9) A2ML1 CPAMD9 Homo sapiens (Human) negative regulation of peptidase activity [GO:0010466]; regulation of endopeptidase activity [GO:0052548] extracellular exosome [GO:0070062]; extracellular space [GO:0005615] peptidase inhibitor activity [GO:0030414]; serine-type endopeptidase inhibitor activity [GO:0004867] 0.96224 -2.554 EQLPDKCR 0 0 0 9.80972 0 0 0 0 0 0 0 0 0 0 0 0 9.32294 0 0 0 0 0 0 0 0 0 10.9632 A8K8P3 SFI1_HUMAN Protein SFI1 homolog (hSFI1) SFI1 KIAA0542 Homo sapiens (Human) centriole [GO:0005814]; cytosol [GO:0005829] phosphatase binding [GO:0019902] 0.96987 -4.2711 ALHASALK 0 0 0 0 0 0 0 0 10.6792 0 0 0 9.41325 0 0 0 0 0 0 0 0 0 0 0 0 0 13.0883 A8K979 ERI2_HUMAN ERI1 exoribonuclease 2 (EC 3.1.-.-) (Exonuclease domain-containing protein 1) ERI2 EXOD1 KIAA1504 Homo sapiens (Human) "exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]" 3'-5'-RNA exonuclease activity [GO:0000175]; nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270] 0.96914 -4.4853 ATYKLFYR 0 10.9767 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6491 0 0 0 0 0 0 0 0 0 0 0 A8MPP1 D11L8_HUMAN Putative ATP-dependent RNA helicase DDX11-like protein 8 (EC 3.6.4.13) (DEAD/H box protein 11-like 8) DDX11L8 Homo sapiens (Human) DNA duplex unwinding [GO:0032508]; establishment of sister chromatid cohesion [GO:0034085]; nucleobase-containing compound metabolic process [GO:0006139] nucleolus [GO:0005730]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.93324 -1.2654 AVVIAGGTMQPVSDFR 0 0 0 9.56773 0 9.24555 0 0 0 0 0 0 0 0 0 0 9.23429 0 0 0 0 0 0 10.0161 0 0 0 A8MPS7 YDJC_HUMAN Carbohydrate deacetylase (EC 3.5.1.-) YDJC Homo sapiens (Human) carbohydrate metabolic process [GO:0005975] deacetylase activity [GO:0019213]; magnesium ion binding [GO:0000287] 0.95994 -1.931 MSRPRMRLVVTADDFGYCPR 0 0 0 12.3686 0 0 0 0 10.8642 0 0 0 0 0 0 14.993 0 14.7187 0 0 0 0 0 12.186 0 0 0 A8MPX8 PP2D1_HUMAN Protein phosphatase 2C-like domain-containing protein 1 PP2D1 C3orf48 Homo sapiens (Human) protein dephosphorylation [GO:0006470] protein serine/threonine phosphatase activity [GO:0004722] 0.21654 0.90015 LLSSFMFTEK 0 0 0 0 0 0 0 0 0 0 0 0 10.6833 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A8MQ14 ZN850_HUMAN Zinc finger protein 850 ZNF850 Homo sapiens (Human) nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.88402 -0.17103 NRHQRIHTGEKPYNCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.67599 0 0 0 0 0 A8MQT2 GOG8B_HUMAN Golgin subfamily A member 8B (Golgin-67) GOLGA8B Homo sapiens (Human) Golgi organization [GO:0007030]; spindle assembly [GO:0051225] cis-Golgi network [GO:0005801]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi cis cisterna [GO:0000137]; Golgi cisterna membrane [GO:0032580] 0.88399 -0.27839 ELEGQIQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.71486 0 0 0 0 0 0 0 0 0 0 0 A8MT19 RHN2P_HUMAN Putative rhophilin-2-like protein RHPN2P1 (Rhophilin-2 pseudogene 1) RHPN2P1 Homo sapiens (Human) negative regulation of stress fiber assembly [GO:0051497] 0.9643 -2.2644 LSFLSWGTNKNR 0 0 0 0 8.97877 0 0 0 0 0 0 0 0 0 0 9.14586 0 0 0 0 0 0 0 0 0 0 10.3217 A8MT33 SYC1L_HUMAN Synaptonemal complex central element protein 1-like (Meiosis-related protein) SYCE1L Homo sapiens (Human) synaptonemal complex assembly [GO:0007130] intermediate filament cytoskeleton [GO:0045111]; synaptonemal complex [GO:0000795] 0.89771 -0.5495 DLWEFHMLEQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0229 0 0 0 0 0 9.94701 0 0 0 0 0 0 A8MT65 ZN891_HUMAN Zinc finger protein 891 ZNF891 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.76541 0.28223 EDWECHK 0 0 10.0269 0 0 0 0 0 0 9.61875 0 0 0 0 0 0 0 0 0 0 0 9.68993 0 0 0 0 0 A8MT70 ZBBX_HUMAN Zinc finger B-box domain-containing protein 1 ZBBX Homo sapiens (Human) metal ion binding [GO:0046872] 0.95527 -1.5579 DFLNLCLRNSSTYYK 0 11.8611 0 0 0 0 0 11.2507 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A8MTI9 PRS47_HUMAN "Putative serine protease 47 (EC 3.4.21.-) (Serine protease 47, pseudogene)" PRSS47P PRSS47 Homo sapiens (Human) proteolysis [GO:0006508] extracellular space [GO:0005615] serine-type endopeptidase activity [GO:0004252] 0.92485 -1.1757 IITHPDFEK 10.9557 0 0 0 0 0 0 0 0 10.7974 11.2164 0 0 9.86462 0 0 0 0 0 0 0 0 0 0 0 0 0 A8MTL0 IQCF5_HUMAN IQ domain-containing protein F5 IQCF5 Homo sapiens (Human) calmodulin binding [GO:0005516] 0.81298 0.22418 IIQVYWR 0 0 0 0 0 0 0 0 0 0 0 0 10.4202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A8MTL9 HMSD_HUMAN Serpin-like protein HMSD (Minor histocompatibility protein HMSD) (Minor histocompatibility serpin domain-containing protein) HMSD Homo sapiens (Human) activation of immune response [GO:0002253]; negative regulation of peptidase activity [GO:0010466] extracellular space [GO:0005615] serine-type endopeptidase inhibitor activity [GO:0004867] 0.78899 0.25012 TANGLFGEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.45014 0 0 0 0 0 0 0 0 0 A8MTT3 CEBOS_HUMAN Protein CEBPZOS (CEBPZ antisense RNA 1) (CEBPZ opposite strand) CEBPZOS CEBPZ-AS1 Homo sapiens (Human) mitochondrial membrane [GO:0031966] 0.95914 -1.9145 MHTSQDFRQTMSKK 0 0 0 0 0 0 8.99531 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A8MTY0 ZN724_HUMAN Zinc finger protein 724 ZNF724 ZNF724P Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.85059 0.10794 IIHTGEKPYKCK 9.70134 0 0 0 0 0 14.6853 10.4414 0 0 0 0 0 8.57833 0 0 0 0 0 0 0 0 10.4768 0 0 0 0 A8MTZ7 CL071_HUMAN Uncharacterized protein C12orf71 C12orf71 Homo sapiens (Human) 0.96204 -2.6183 ERTKLSVGK 0 9.96824 0 9.59421 0 0 0 0 0 0 0 10.8512 0 0 0 0 0 0 0 10.3017 0 0 0 0 0 0 0 A8MU46 SMTL1_HUMAN Smoothelin-like protein 1 SMTNL1 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; muscle organ morphogenesis [GO:0048644]; negative regulation of DNA-templated transcription [GO:0045892]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of vasoconstriction [GO:0045907]; response to activity [GO:0014823]; response to xenobiotic stimulus [GO:0009410]; vasoconstriction [GO:0042310] contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; I band [GO:0031674]; M band [GO:0031430]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634] calmodulin binding [GO:0005516]; CH domain binding [GO:0051401]; disordered domain specific binding [GO:0097718]; protein phosphatase 1 binding [GO:0008157]; protein self-association [GO:0043621]; tropomyosin binding [GO:0005523] 0.96943 -5.5185 AESQKAVVEDEAKAEPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3357 0 0 0 0 0 0 0 0 0 0 0 A8MUK1 U17L5_HUMAN Ubiquitin carboxyl-terminal hydrolase 17-like protein 5 (EC 3.4.19.12) (Deubiquitinating enzyme 17-like protein 5) (Ubiquitin thioesterase 17-like protein 5) (Ubiquitin-specific-processing protease 17-like protein 5) USP17L5 Homo sapiens (Human) apoptotic process [GO:0006915]; protein deubiquitination [GO:0016579]; regulation of apoptotic process [GO:0042981]; ubiquitin-dependent protein catabolic process [GO:0006511] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634] cysteine-type deubiquitinase activity [GO:0004843]; cysteine-type endopeptidase activity [GO:0004197] 0.87133 0.061905 EDDSLYLRGEWQFNHFSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.69401 0 0 0 0 0 0 0 0 A8MUP6 GS1L2_HUMAN Germ cell-specific gene 1-like protein 2 (GSG1-like protein 2) GSG1L2 Homo sapiens (Human) plasma membrane [GO:0005886] 0.96197 -2.5603 DNSSNGR 0 0 0 0 0 0 0 0 0 0 0 9.31277 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A8MUV8 ZN727_HUMAN Putative zinc finger protein 727 (Zinc finger protein 727 pseudogene) ZNF727 ZNF727P Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.88998 -0.48721 LSDFTIQK 11.0664 0 0 0 0 0 0 0 0 0 0 0 0 10.6437 0 0 0 0 0 0 0 0 0 0 0 10.2304 0 A8MUZ8 Z705G_HUMAN Putative zinc finger protein 705G ZNF705G Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.96012 -1.8102 KCYECDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.3751 0 0 0 A8MV72 YH009_HUMAN Putative UPF0607 protein ENSP00000382826 Homo sapiens (Human) 0.96948 -4.9691 AAGHRSR 0 0 0 0 0 0 0 9.3456 0 0 0 0 0 0 0 0 0 0 0 0 9.72892 0 0 0 0 0 8.30861 A8MVM7 YD021_HUMAN Putative uncharacterized protein ENSP00000382790 Homo sapiens (Human) 0.96783 -3.6843 IRHTEADIFKNGSK 0 0 0 0 8.87357 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1579 0 10.8111 0 0 0 0 0 0 A8MVW5 HECA2_HUMAN HEPACAM family member 2 (Mitotic kinetics regulator) HEPACAM2 MIKI UNQ305/PRO346 Homo sapiens (Human) cell division [GO:0051301]; centrosome cycle [GO:0007098] centrosome [GO:0005813]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; nucleoplasm [GO:0005654]; spindle [GO:0005819] 0.78633 0.24955 VAQKTMDYVCCAYNNITGR 0 0 0 0 0 0 9.58982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A8MVX0 ARG33_HUMAN Rho guanine nucleotide exchange factor 33 ARHGEF33 Homo sapiens (Human) guanyl-nucleotide exchange factor activity [GO:0005085] 0.81197 0.22365 SVHVGDSNVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2667 0 0 0 0 0 A8MW92 P20L1_HUMAN PHD finger protein 20-like protein 1 PHF20L1 CGI-72 Homo sapiens (Human) histone acetylation [GO:0016573]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein catabolic process [GO:0042177]; regulation of transcription by RNA polymerase II [GO:0006357] NSL complex [GO:0044545]; nucleus [GO:0005634] metal ion binding [GO:0046872]; methylation-dependent protein binding [GO:0140034] 0.87124 0.037626 DQDQIIAGVEK 0 0 0 0 0 11.5527 0 9.59809 0 0 0 0 9.13558 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A8MWK0 FS2P1_HUMAN "Putative fatty acid desaturase 2-like protein FADS2B (Fatty acid desaturase 2 pseudogene 1) (Fatty acid desaturase 2B, pseudogene)" FADS2B FADS2P1 Homo sapiens (Human) lipid metabolic process [GO:0006629]; unsaturated fatty acid biosynthetic process [GO:0006636] endoplasmic reticulum membrane [GO:0005789] "metal ion binding [GO:0046872]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]" 0.8714 0.030422 YINYEEQHLYFYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.29313 0 A8MWX3 WASH4_HUMAN Putative WAS protein family homolog 4 (Protein FAM39CP) WASH4P FAM39CP Homo sapiens (Human) "Arp2/3 complex-mediated actin nucleation [GO:0034314]; endocytic recycling [GO:0032456]; endosomal transport [GO:0016197]; exocytosis [GO:0006887]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315]; retrograde transport, endosome to Golgi [GO:0042147]" cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; WASH complex [GO:0071203] actin binding [GO:0003779]; alpha-tubulin binding [GO:0043014]; gamma-tubulin binding [GO:0043015] 0.96808 -2.9171 IQSKQRPLDER 0 0 0 0 0 0 0 10.5658 0 10.7091 0 10.6733 10.6737 0 11.5247 11.325 0 0 0 0 0 0 0 9.96737 0 0 0 A8MX76 CAN14_HUMAN Calpain-14 (EC 3.4.22.-) (Calcium-activated neutral proteinase 14) (CANP 14) CAPN14 Homo sapiens (Human) proteolysis [GO:0006508] cytoplasm [GO:0005737] calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198] 0.84775 0.12605 GIYLQKPEWMMMALYS 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.28313 0 0 0 0 0 0 0 0 0 0 0 A8MXE2 B3GT9_HUMAN "Beta-1,3-galactosyltransferase 9 (EC 2.4.1.-) (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 10)" B3GALT9 B3GNT10 Homo sapiens (Human) protein O-linked glycosylation [GO:0006493] Golgi membrane [GO:0000139]; membrane [GO:0016020] hexosyltransferase activity [GO:0016758] 0.95511 -1.5691 EINKESCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.93232 0 0 A8MXV4 NUD19_HUMAN Acyl-coenzyme A diphosphatase NUDT19 (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 19) (Nudix motif 19) NUDT19 Homo sapiens (Human) butyryl-CoA catabolic process [GO:0044580]; coenzyme A catabolic process [GO:0015938]; fatty acid catabolic process [GO:0009062]; malonyl-CoA catabolic process [GO:2001294]; medium-chain fatty-acyl-CoA catabolic process [GO:0036114]; propionyl-CoA metabolic process [GO:1902858]; succinyl-CoA catabolic process [GO:1901289] cytosol [GO:0005829]; peroxisomal matrix [GO:0005782] acyl-coenzyme A diphosphatase activity [GO:0106399]; CoA pyrophosphatase activity [GO:0010945]; magnesium ion binding [GO:0000287] 0.89732 -0.52835 DRVRQDPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.20176 0 0 0 0 0 0 0 A8MXY4 ZNF99_HUMAN Zinc finger protein 99 ZNF99 C19orf9 Homo sapiens (Human) nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.9213 -1.1391 AIHTGEKPYK 11.0473 0 0 9.9714 10.2501 0 0 0 0 0 0 0 0 0 0 12.315 12.4584 0 0 0 0 0 0 0 0 0 0 A8MYJ7 TTC34_HUMAN Tetratricopeptide repeat protein 34 (TPR repeat protein 34) TTC34 Homo sapiens (Human) 0.94829 -1.3706 DLDHVLQEALGDGDLPR 0 0 0 0 0 9.0126 0 0 0 0 0 0 0 0 0 0 0 0 0 8.69349 0 0 0 0 0 0 0 A8MYU2 KCNU1_HUMAN "Potassium channel subfamily U member 1 (Calcium-activated potassium channel subunit alpha-3) (Calcium-activated potassium channel, subfamily M subunit alpha-3) (KCa5) (Slowpoke homolog 3)" KCNU1 KCNMA3 KCNMC1 SLO3 Homo sapiens (Human) regulation of monoatomic ion transmembrane transport [GO:0034765]; reproductive process [GO:0022414] plasma membrane [GO:0005886] potassium channel activity [GO:0005267]; voltage-gated monoatomic ion channel activity [GO:0005244] 0.9241 -0.99557 FMAADDKIK 0 9.8603 0 0 0 0 8.95725 0 0 0 0 0 0 0 10.0898 0 0 0 0 0 0 0 0 0 0 10.1485 0 A8MYV0 DCD2C_HUMAN Doublecortin domain-containing protein 2C DCDC2C Homo sapiens (Human) intracellular signal transduction [GO:0035556] cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule organizing center [GO:0005815]; sperm flagellum [GO:0036126] 0.89437 -0.5175 FKELDYIHIVPR 0 0 15.4348 0 0 0 0 14.8126 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A8MZA4 GG6L6_HUMAN Golgin subfamily A member 6-like protein 6 GOLGA6L6 Homo sapiens (Human) 0.91572 -0.81 MCEQEEKMQEQEETMWR 0 0 0 0 0 0 0 0 0 0 10.3433 10.3157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A8TX70 CO6A5_HUMAN Collagen alpha-5(VI) chain (Collagen alpha-1(XXIX) chain) (von Willebrand factor A domain-containing protein 4) COL6A5 COL29A1 VWA4 Homo sapiens (Human) cell adhesion [GO:0007155] collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576] extracellular matrix structural constituent conferring tensile strength [GO:0030020] 0.92991 -1.2397 GFPGDPGNPGQNNNIKGQK 0 0 0 0 9.59895 0 0 0 0 0 0 11.3369 0 0 0 0 0 0 0 0 0 0 0 9.57647 0 9.63804 0 A9Z1Z3 FR1L4_HUMAN Fer-1-like protein 4 FER1L4 C20orf124 Homo sapiens (Human) regulation of neurotransmitter secretion [GO:0046928] synaptic vesicle membrane [GO:0030672] calcium ion binding [GO:0005509] 0.79835 0.23968 GPELCSVQLAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.37106 0 0 0 B0I1T2 MYO1G_HUMAN Unconventional myosin-Ig [Cleaved into: Minor histocompatibility antigen HA-2 (mHag HA-2)] MYO1G HA2 Homo sapiens (Human) actin filament organization [GO:0007015]; cell gliding [GO:0071976]; cell-substrate adhesion [GO:0031589]; exocytosis [GO:0006887]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; T cell meandering migration [GO:0120117]; T cell mediated immunity [GO:0002456]; T cell migration [GO:0072678]; vesicle transport along actin filament [GO:0030050] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microvillus [GO:0005902]; myosin complex [GO:0016459]; nucleoplasm [GO:0005654]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; vesicle [GO:0031982] "actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; cytoskeletal motor activity [GO:0003774]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]" 0.96777 -3.8149 AGFASRQPYSRFLLR 0 0 0 0 0 0 0 0 0 0 0 0 9.64559 10.0608 0 9.64665 9.5403 0 0 11.718 0 0 9.78252 0 0 0 0 B0YJ81 HACD1_HUMAN Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase 1) (HACD1) (Cementum-attachment protein) (CAP) (Protein-tyrosine phosphatase-like member A) HACD1 PTPLA Homo sapiens (Human) cementum mineralization [GO:0071529]; fatty acid elongation [GO:0030497]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; positive regulation of cell-substrate adhesion [GO:0010811]; protein-containing complex assembly [GO:0065003]; sphingolipid biosynthetic process [GO:0030148]; very long-chain fatty acid biosynthetic process [GO:0042761] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789] 3-hydroxyacyl-CoA dehydratase activity [GO:0018812]; enzyme binding [GO:0019899]; hydroxyapatite binding [GO:0046848] 0.7701 0.2757 LTEAAAAGSGSR 0 0 0 0 0 0 0 0 0 0 10.6041 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 B1AJZ9 FHAD1_HUMAN Forkhead-associated domain-containing protein 1 (FHA domain-containing protein 1) FHAD1 KIAA1937 Homo sapiens (Human) 0.96725 -2.8453 AAGASGR 0 10.1693 0 0 8.8464 0 9.53424 0 0 0 0 8.71521 0 0 0 0 0 0 0 8.83652 10.3497 10.9905 11.2574 7.98453 10.7319 9.11749 0 B1AK53 ESPN_HUMAN Espin (Autosomal recessive deafness type 36 protein) (Ectoplasmic specialization protein) ESPN DFNB36 LP2654 Homo sapiens (Human) actin filament bundle assembly [GO:0051017]; microvillar actin bundle assembly [GO:0030034]; sensory perception of sound [GO:0007605] brush border [GO:0005903]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; microvillus [GO:0005902]; stereocilium [GO:0032420]; stereocilium tip [GO:0032426] actin filament binding [GO:0051015]; SH3 domain binding [GO:0017124] 0.96178 -2.0274 EKEQSEKLR 0 0 0 0 0 0 0 0 10.0688 0 0 0 0 0 0 0 0 0 10.2016 0 0 0 0 0 0 0 0 B1ANS9 WDR64_HUMAN WD repeat-containing protein 64 WDR64 Homo sapiens (Human) 0.95985 -1.9329 ALNRFEK 0 9.07157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.794 0 0 9.7417 0 0 0 B1APH4 ZN487_HUMAN Putative zinc finger protein 487 (KRAB domain only protein 1) ZNF487 KRBO1 ZNF487P Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.88563 -0.29201 NPAECNVRGK 0 0 0 0 0 0 0 0 0 10.1237 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 B2RD01 CENP1_HUMAN Putative CENPB DNA-binding domain-containing protein 1 CENPBD1P CENPBD1 Homo sapiens (Human) nucleus [GO:0005634] DNA binding [GO:0003677] 0.93924 -1.3209 AITLDLKLEVLRR 11.5382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 B2RPK0 HGB1A_HUMAN Putative high mobility group protein B1-like 1 (High mobility group protein B1 pseudogene 1) (Putative high mobility group protein 1-like 1) (HMG-1L1) HMGB1P1 HMG1L1 HMGB1L1 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] chromosome [GO:0005694]; nucleus [GO:0005634] "DNA binding, bending [GO:0008301]" 0.84409 0.1376 FKDPNAPK 0 0 0 0 0 0 0 0 0 0 0 0 8.50577 0 0 0 0 0 0 0 0 0 0 0 0 0 0 B2RTY4 MYO9A_HUMAN Unconventional myosin-IXa (Unconventional myosin-9a) MYO9A MYR7 Homo sapiens (Human) cell junction assembly [GO:0034329]; establishment of epithelial cell apical/basal polarity [GO:0045198]; intracellular signal transduction [GO:0035556]; positive regulation of GTPase activity [GO:0043547]; regulation of neuron projection arborization [GO:0150011]; regulation of small GTPase mediated signal transduction [GO:0051056]; visual perception [GO:0007601] axonal growth cone [GO:0044295]; cytosol [GO:0005829]; membrane [GO:0016020]; synapse [GO:0045202]; unconventional myosin complex [GO:0016461] actin filament binding [GO:0051015]; ATP binding [GO:0005524]; GTPase activator activity [GO:0005096]; metal ion binding [GO:0046872]; microfilament motor activity [GO:0000146] 0.9687 -8.6 AMGLQER 0 0 0 0 0 0 0 0 0 9.58489 18.7385 11.0715 0 10.481 0 0 0 9.49007 9.20609 0 0 10.3099 0 9.53712 0 0 0 B2RU33 POTEC_HUMAN "POTE ankyrin domain family member C (ANKRD26-like family B member 2) (Prostate, ovary, testis-expressed protein on chromosome 18) (POTE-18)" POTEC A26B2 POTE18 Homo sapiens (Human) 0.95992 -1.9275 DLIVMLRDTDMNKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8704 0 10.5777 0 0 0 0 0 0 0 0 11.6271 B2RV13 CF97D_HUMAN Sperm axonemal maintenance protein CFAP97D1 (CFAP97 domain-containing protein 1) CFAP97D1 C17orf105 Homo sapiens (Human) sperm axoneme assembly [GO:0007288] 0.81616 0.22134 LDFGHYVSHK 0 0 0 0 0 0 0 0 0 0 9.91112 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 B2RXF0 T229A_HUMAN Transmembrane protein 229A TMEM229A Homo sapiens (Human) membrane [GO:0016020] 0.86401 0.086833 LYFHLHYSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.8981 0 0 0 0 0 0 0 0 0 0 B2RXF5 ZBT42_HUMAN Zinc finger and BTB domain-containing protein 42 ZBTB42 Homo sapiens (Human) muscle organ development [GO:0007517]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] "DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]" 0.8711 0.027601 RFTQSGDLYRHVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5153 8.97593 0 0 0 0 0 B2RXH2 KDM4E_HUMAN Lysine-specific demethylase 4E (EC 1.14.11.66) (KDM4D-like protein) (Lysine-specific demethylase 4D-like) ([histone H3]-trimethyl-L-lysine(9) demethylase 4E) KDM4E KDM4DL Homo sapiens (Human) chromatin remodeling [GO:0006338] nucleus [GO:0005634] histone H3K9 demethylase activity [GO:0032454]; histone H3K9me2/H3K9me3 demethylase activity [GO:0140684]; metal ion binding [GO:0046872] 0.86976 0.051923 QDLAIVEHTEPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.72127 0 0 0 0 0 0 0 0 0 0 0 B3GLJ2 PATE3_HUMAN Prostate and testis expressed protein 3 (Acrosomal vesicle protein HEL-127) (PATE-like protein DJ) (PATE-DJ) PATE3 Homo sapiens (Human) extracellular region [GO:0005576] 0.88549 -0.33175 DMTFDLRNR 0 0 0 0 0 0 0 0 8.58226 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 B3KS81 SRRM5_HUMAN Serine/arginine repetitive matrix protein 5 SRRM5 ZNF576 Homo sapiens (Human) 0.96875 -5.8076 ARDCSRSR 0 0 0 0 0 0 0 0 8.0964 0 0 0 0 0 0 0 0 0 8.63005 0 9.34725 0 0 0 9.93232 0 0 B4DH59 NBPFP_HUMAN Neuroblastoma breakpoint family member 26 NBPF26 Homo sapiens (Human) cytoplasm [GO:0005737] 0.83045 0.21024 LSGELLDEK 0 0 0 0 0 0 0 0 0 0 9.23431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 B4DX44 ZN736_HUMAN Zinc finger protein 736 ZNF736 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.9633 -2.6758 CGRGFQLCSIFTEHKDIFSR 0 0 0 12.4971 0 0 14.7745 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 B4DXR9 ZN732_HUMAN Zinc finger protein 732 ZNF732 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96926 -3.9958 AFLCSRALNK 14.1335 0 14.1459 10.7248 10.6662 10.668 0 0 0 0 14.1197 0 9.33865 10.5335 9.45588 10.9044 10.9792 10.8454 0 0 0 0 0 0 0 0 0 B4DYI2 S31C2_HUMAN Putative spermatogenesis-associated protein 31C2 (Protein FAM75C2) SPATA31C2 FAM75C2 Homo sapiens (Human) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] membrane [GO:0016020] 0.97008 -5.0328 CDNPPSPSPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.27254 0 0 0 0 0 0 0 0 9.64811 0 0 10.3191 B5MCY1 TDR15_HUMAN Tudor domain-containing protein 15 TDRD15 Homo sapiens (Human) 0.9682 -2.77 DLEMIETK 0 0 0 0 0 0 0 9.65859 0 9.02242 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.81758 0 B7Z1M9 C2D4D_HUMAN C2 calcium-dependent domain-containing protein 4D C2CD4D FAM148D Homo sapiens (Human) 0.8738 0.024813 VSRPHSLSPEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.40958 0 0 0 0 0 0 0 0 0 0 B7Z368 CJ142_HUMAN Uncharacterized protein encoded by LINC02881 (Long intergenic non-protein coding RNA 2881) LINC02881 C10orf142 Homo sapiens (Human) 0.88471 -0.19611 QDSAAGNSEER 9.78616 0 0 0 0 0 0 0 0 10.6057 0 10.1478 0 0 0 0 0 0 10.0312 0 0 0 0 0 0 0 0 B7ZAP0 RBG10_HUMAN "Rab GTPase-activating protein 1-like, isoform 10" RABGAP1L HHL KIAA0471 Homo sapiens (Human) 0.37264 0.72807 GALMNEIQAAK 8.22752 0 0 0 0 0 8.64418 0 0 0 0 0 0 10.6185 0 0 0 0 0 0 0 10.4223 0 0 0 0 0 B7ZBB8 PP13G_HUMAN Protein phosphatase 1 regulatory subunit 3G PPP1R3G Homo sapiens (Human) glucose homeostasis [GO:0042593]; glycogen biosynthetic process [GO:0005978]; positive regulation of glycogen (starch) synthase activity [GO:2000467]; positive regulation of glycogen biosynthetic process [GO:0045725]; regulation of glycogen biosynthetic process [GO:0005979] protein phosphatase type 1 complex [GO:0000164] glycogen binding [GO:2001069]; protein phosphatase 1 binding [GO:0008157] 0.19315 0.92979 RVQFADTLGLSLASVK 0 0 0 0 0 0 8.54404 8.92769 10.7981 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 B7ZC32 KIF28_HUMAN Kinesin-like protein KIF28P (Kinesin-like protein 6) KIF28P KLP6 Homo sapiens (Human) cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]; mitochondrion organization [GO:0007005]; organelle transport along microtubule [GO:0072384] kinesin complex [GO:0005871]; microtubule [GO:0005874]; mitochondrial membrane [GO:0031966] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777] 0.92008 -1.141 EKNSGSKCVISMHSR 0 0 0 0 0 0 0 0 0 0 9.45162 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 B8ZZ34 SHSA8_HUMAN Protein shisa-8 (Shisa family member 8) SHISA8 C22orf17 Homo sapiens (Human) regulation of AMPA receptor activity [GO:2000311]; regulation of short-term neuronal synaptic plasticity [GO:0048172] AMPA glutamate receptor complex [GO:0032281]; dendritic spine membrane [GO:0032591]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211] 0.58602 0.46597 GSAAPGPPR 0 0 0 0 0 0 0 8.65996 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 B9A064 IGLL5_HUMAN Immunoglobulin lambda-like polypeptide 5 (G lambda-1) (Germline immunoglobulin lambda 1) IGLL5 Homo sapiens (Human) external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062] 0.95384 -1.5003 SSLRSLWGR 0 0 0 0 9.38236 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 C0HLS1 OSCRI_HUMAN SCRIB overlapping open reading frame protein (oSCRIB) SCRIB Homo sapiens (Human) negative regulation of translational initiation [GO:0045947] 0.46029 0.63751 RTEPRPPAPSPPSAAAGAR 10.3682 0 0 0 0 0 0 0 0 0 0 10.8965 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 C9J069 AJM1_HUMAN Apical junction component 1 homolog AJM1 C9orf172 Homo sapiens (Human) cell-cell junction organization [GO:0045216] adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical plasma membrane [GO:0016324]; cilium [GO:0005929]; plasma membrane [GO:0005886] 0.96885 -3.3366 AYGLPYGPR 0 0 0 0 0 0 0 0 0 0 0 11.6046 0 0 0 0 0 0 0 0 0 10.4319 0 0 0 0 0 C9J1S8 TR49D_HUMAN Tripartite motif-containing protein 49D (Tripartite motif-containing protein 49-like protein) (Tripartite motif-containing protein 49D1) (Tripartite motif-containing protein 49D2) TRIM49D1 TRIM49L TRIM49L1; TRIM49D2 TRIM49D2P Homo sapiens (Human) innate immune response [GO:0045087]; protein ubiquitination [GO:0016567]; regulation of gene expression [GO:0010468] cytoplasm [GO:0005737] ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.925 -0.98476 LEAIRAEYQK 11.9693 10.5102 10.6119 0 0 0 9.94419 10.0851 9.92784 10.5548 10.6083 10.2841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 C9J202 AG1L2_HUMAN Putative glycosyltransferase ALG1L2 (EC 2.4.1.-) ALG1L2 Homo sapiens (Human) protein glycosylation [GO:0006486] endoplasmic reticulum [GO:0005783] mannosyltransferase activity [GO:0000030] 0.6302 0.40041 CLHELVK 0 12.9444 0 0 11.073 10.915 0 0 12.3763 12.7223 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 C9J302 CD051_HUMAN Uncharacterized protein C4orf51 C4orf51 Homo sapiens (Human) 0.87925 0.019031 YSDYGWGGPSSPFN 0 0 0 0 0 0 9.91737 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 C9JE40 PATL2_HUMAN Protein PAT1 homolog 2 (PAT1-like protein 2) (Protein PAT1 homolog a) (Pat1a) (hPat1a) PATL2 Homo sapiens (Human) deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; negative regulation of cytoplasmic mRNA processing body assembly [GO:0010607]; negative regulation of translation [GO:0017148]; P-body assembly [GO:0033962] cytoplasm [GO:0005737]; nucleus [GO:0005634]; P-body [GO:0000932] RNA binding [GO:0003723] 0.8695 0.057847 ILQQQQHSQTPSPPAK 0 0 0 0 0 0 0 0 0 11.9336 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 C9JL84 HHLA1_HUMAN HERV-H LTR-associating protein 1 HHLA1 Homo sapiens (Human) extracellular region [GO:0005576] 0.91653 -0.77418 RVSHSHTLK 0 0 0 0 8.18903 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 C9JLR9 ZFTA_HUMAN Zinc finger translocation-associated protein (ZFTA) ZFTA C11orf95 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892] nucleus [GO:0005634] 0.27524 0.83916 SGAVCRA 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.74987 C9JN71 ZN878_HUMAN Zinc finger protein 878 ZNF878 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.95906 -1.7343 GFISSTSFRYHEK 0 0 0 0 0 11.437 0 0 0 0 0 9.36021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 C9JQI7 TM232_HUMAN Transmembrane protein 232 TMEM232 Homo sapiens (Human) membrane [GO:0016020] 0.95804 -1.6885 DQTKYPNK 0 12.2249 0 0 0 0 0 9.23534 0 0 0 0 0 0 0 9.98527 0 0 10.2473 10.1829 10.0935 0 11.2685 0 0 9.98613 0 C9JRZ8 AK1BF_HUMAN Aldo-keto reductase family 1 member B15 (EC 1.1.1.-) (EC 1.1.1.300) (EC 1.1.1.54) (Estradiol 17-beta-dehydrogenase AKR1B15) (Farnesol dehydrogenase) (EC 1.1.1.216) (Testosterone 17beta-dehydrogenase) (EC 1.1.1.64) AKR1B15 Homo sapiens (Human) estrogen biosynthetic process [GO:0006703] cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] "alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; estradiol 17-beta-dehydrogenase [NAD(P)] activity [GO:0004303]; farnesol dehydrogenase activity [GO:0047886]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]" 0.88425 -0.25613 TGDDFFPK 0 0 9.72753 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1992 0 0 0 0 0 0 0 0 0 0 C9JVW0 INAM1_HUMAN Putative transmembrane protein INAFM1 (InaF-motif-containing protein 1) (Proline-rich protein 24) INAFM1 PRR24 Homo sapiens (Human) membrane [GO:0016020] 0.88209 -0.09609 MRGTSCVGGGAESPGGAGLSEGPRGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0804 0 0 0 0 0 0 0 D6REC4 CFA99_HUMAN Cilia- and flagella-associated protein 99 CFAP99 Homo sapiens (Human) motile cilium [GO:0031514] 0.96957 -3.5095 AGAGWGWRAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9977 0 0 0 0 0 0 0 0 0 9.8448 9.96809 D6RGH6 MCIN_HUMAN Multicilin (Multiciliate differentiation and DNA synthesis-associated cell cycle protein) (McIdas protein) (Protein Idas) MCIDAS IDAS MCI MCIN Homo sapiens (Human) cell cycle [GO:0007049]; centriole assembly [GO:0098534]; cilium assembly [GO:0060271]; motile cilium assembly [GO:0044458]; multi-ciliated epithelial cell differentiation [GO:1903251]; negative regulation of DNA replication [GO:0008156]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cilium assembly [GO:1902017]; regulation of DNA-templated DNA replication initiation [GO:0030174]; regulation of mitotic cell cycle [GO:0007346] nuclear body [GO:0016604]; nucleus [GO:0005634] identical protein binding [GO:0042802] 0.9619 -2.5603 TANGGYK 0 0 0 0 0 0 0 0 0 0 0 0 10.256 0 0 0 0 0 0 0 0 0 0 0 0 0 0 D6RIA3 CD054_HUMAN Uncharacterized protein C4orf54 (Familial obliterative portal venopathy) C4orf54 FOPV Homo sapiens (Human) 0.9683 -3.6231 AGVVLRGAPIER 12.6819 0 0 0 0 9.92035 11.6268 12.0432 11.7164 11.6084 11.3094 11.2044 0 0 0 0 8.81429 0 11.1895 11.4995 10.7152 0 0 0 11.1824 12.0231 0 E5RHQ5 NPB11_HUMAN Nuclear pore complex-interacting protein family member B11 NPIPB11 Homo sapiens (Human) membrane [GO:0016020]; nucleoplasm [GO:0005654] 0.96524 -2.3712 AAEMEPPPEPKRR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2024 0 0 0 0 0 0 0 0 0 0 0 0 0 E7ERA6 RN223_HUMAN RING finger protein 223 RNF223 Homo sapiens (Human) protein ubiquitination [GO:0016567] membrane [GO:0016020] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630] 0.74477 0.32066 SPSSAGSPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.1738 0 8.87403 E7EW31 PROB1_HUMAN Proline-rich basic protein 1 PROB1 C5orf65 Homo sapiens (Human) nucleoplasm [GO:0005654] 0.96899 -3.3672 DNSAPAKAPRPWPSLR 0 0 0 0 0 0 0 0 9.15975 0 0 8.20462 0 0 0 0 0 0 10.3606 0 0 0 0 0 0 0 9.25875 E9PAV3 NACAM_HUMAN "Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form) (skNAC)" NACA Homo sapiens (Human) protein targeting to membrane [GO:0006612] cytoplasm [GO:0005737]; nascent polypeptide-associated complex [GO:0005854]; nucleus [GO:0005634] DNA binding [GO:0003677]; unfolded protein binding [GO:0051082] 0.96722 -2.8617 DASHSPK 0 0 0 0 9.66496 0 0 0 0 11.4241 9.26404 0 0 0 0 0 0 0 9.56754 0 0 0 10.2778 0 0 0 0 E9PQ53 NDUCR_HUMAN "NADH dehydrogenase [ubiquinone] 1 subunit C2, isoform 2 (NDUFC2-KCTD14 readthrough transcript protein)" NDUFC2-KCTD14 Homo sapiens (Human) "mitochondrial electron transport, NADH to ubiquinone [GO:0006120]" mitochondrial respiratory chain complex I [GO:0005747]; mitochondrion [GO:0005739] 0.93299 -1.2853 IARRNPEPLR 9.07767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 E9PRG8 CK098_HUMAN Uncharacterized protein C11orf98 C11orf98 Homo sapiens (Human) 0.69734 0.37876 APQDVEMK 0 0 0 0 0 0 8.94067 8.57599 0 0 0 8.76195 8.48434 0 0 0 0 9.10182 0 0 0 0 0 0 0 0 0 F5H4A9 CC080_HUMAN Uncharacterized membrane protein C3orf80 C3orf80 Homo sapiens (Human) membrane [GO:0016020] 0.91456 -0.79606 IICPSPRR 0 0 0 0 0 0 0 0 9.61397 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 F5H4B4 F227A_HUMAN Protein FAM227A FAM227A Homo sapiens (Human) 0.92303 -1.1477 EELMLYR 12.0792 11.9232 11.8004 9.47557 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.003 0 0 G9CGD6 CNIPF_HUMAN CNK3/IPCEF1 fusion protein CNK3/IPCEF1 Homo sapiens (Human) positive regulation of cellular response to hepatocyte growth factor stimulus [GO:2001114]; regulation of signal transduction [GO:0009966] cytoplasm [GO:0005737]; membrane [GO:0016020] 0.96951 -3.1564 EETKVSEDDEMEK 0 0 12.1024 11.7415 9.98982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.56885 0 0 0 0 10.1648 H3BPF8 GOG8S_HUMAN Golgin subfamily A member 8S GOLGA8S Homo sapiens (Human) Golgi organization [GO:0007030]; spindle assembly [GO:0051225] cis-Golgi network [GO:0005801]; Golgi cis cisterna [GO:0000137]; Golgi cisterna membrane [GO:0032580] 0.88614 -0.33903 ARTEWKLEQSMR 0 0 0 0 0 0 8.79724 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 H3BQB6 STMD1_HUMAN Stathmin domain-containing protein 1 STMND1 Homo sapiens (Human) microtubule depolymerization [GO:0007019]; neuron projection development [GO:0031175]; regulation of microtubule polymerization or depolymerization [GO:0031110] cytoplasm [GO:0005737]; neuron projection [GO:0043005] tubulin binding [GO:0015631] 0.90801 -0.74252 SDRLLPSANHSDSAELDGAEVAFAK 0 0 10.1721 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 H3BU77 CC179_HUMAN Coiled-coil domain-containing protein 179 CCDC179 Homo sapiens (Human) 0.91537 -0.77118 IQNMQHLKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6263 0 0 0 0 0 0 0 0 0 H3BV12 GOG8Q_HUMAN Golgin subfamily A member 8Q GOLGA8Q Homo sapiens (Human) Golgi organization [GO:0007030] cis-Golgi network [GO:0005801]; Golgi cis cisterna [GO:0000137]; Golgi cisterna membrane [GO:0032580] 0.76316 0.28961 EELNTDLYHMERSLR 0 0 0 0 0 0 0 0 0 0 9.39157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3325 H7BZ55 CRCC2_HUMAN Ciliary rootlet coiled-coil protein 2 CROCC2 Homo sapiens (Human) centriole [GO:0005814]; centrosome [GO:0005813] 0.96956 -5.4755 ALAEAEEGQRR 0 0 0 0 0 0 0 0 0 11.1209 0 0 0 0 11.5501 0 9.65076 9.68471 0 9.52882 0 0 0 9.37106 11.0274 0 10.8906 H7C350 CC188_HUMAN Coiled-coil domain-containing protein 188 CCDC188 Homo sapiens (Human) membrane [GO:0016020] 0.91659 -0.84807 RQNQELR 9.84027 0 9.71845 0 0 0 10.0507 10.0743 0 10.4008 0 10.2222 0 0 0 0 0 0 0 0 0 10.145 0 0 0 0 0 I0J062 PANO1_HUMAN Proapoptotic nucleolar protein 1 PANO1 PANO Homo sapiens (Human) apoptotic process [GO:0006915]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of apoptotic process [GO:0043065]; regulation of protein stability [GO:0031647] nucleolus [GO:0005730] 0.91477 -0.79606 ADTHHARR 8.09919 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 I1YAP6 TRI77_HUMAN Tripartite motif-containing protein 77 TRIM77 TRIM77P Homo sapiens (Human) innate immune response [GO:0045087]; protein ubiquitination [GO:0016567]; regulation of gene expression [GO:0010468] cytoplasm [GO:0005737] ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.97024 -5.1816 HATHKHYMTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.16269 0 0 0 0 9.85425 0 0 0 0 I3L1E1 CS084_HUMAN Uncharacterized protein C19orf84 C19orf84 Homo sapiens (Human) 0.94809 -1.3629 AEQPERGRAGGPGAGPR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.007 0 0 0 0 0 0 0 0 0 0 0 0 0 I3L273 GFY_HUMAN Golgi-associated olfactory signaling regulator (Golgi protein in olfactory neurons) (Goofy) GFY Homo sapiens (Human) non-motile cilium assembly [GO:1905515]; protein localization to non-motile cilium [GO:0097499]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608] Golgi membrane [GO:0000139] 0.88368 -0.31701 ADSLTTSISESLDMPK 8.7342 8.52003 0 0 0 0 8.53298 0 0 9.17368 0 0 0 0 0 0 0 0 0 0 8.84972 0 0 0 0 0 0 M0QZC1 RN225_HUMAN RING finger protein 225 RNF225 Homo sapiens (Human) protein ubiquitination [GO:0016567] membrane [GO:0016020] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630] 0.94705 -1.3582 APTRLAPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.40035 0 0 0 0 0 0 M0R2J8 DCDC1_HUMAN Doublecortin domain-containing protein 1 (Doublecortin domain-containing 5 protein) DCDC1 DCDC5 KIAA1493 Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; intracellular signal transduction [GO:0035556]; regulation of mitotic cytokinesis [GO:1902412] cytoplasm [GO:0005737]; Flemming body [GO:0090543]; microtubule [GO:0005874]; midbody [GO:0030496]; mitotic spindle [GO:0072686] carbohydrate binding [GO:0030246]; microtubule binding [GO:0008017] 0.9694 -4.6184 AEKLEKQNWLK 9.5494 11.1241 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0641 0 0 0 0 0 0 O00116 ADAS_HUMAN "Alkyldihydroxyacetonephosphate synthase, peroxisomal (Alkyl-DHAP synthase) (EC 2.5.1.26) (Aging-associated gene 5 protein) (Alkylglycerone-phosphate synthase)" AGPS AAG5 Homo sapiens (Human) ether lipid biosynthetic process [GO:0008611]; lipid biosynthetic process [GO:0008610] cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777] alkylglycerone-phosphate synthase activity [GO:0008609]; FAD binding [GO:0071949] 0.92297 -1.0552 IVNLACK 0 0 0 0 0 0 0 10.4598 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O00139 KIF2A_HUMAN Kinesin-like protein KIF2A (Kinesin-2) (hK2) KIF2A KIF2 KNS2 Homo sapiens (Human) cell differentiation [GO:0030154]; cell division [GO:0051301]; microtubule cytoskeleton organization [GO:0000226]; microtubule depolymerization [GO:0007019]; microtubule-based movement [GO:0007018]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; nervous system development [GO:0007399]; regulation of cell migration [GO:0030334] centriolar subdistal appendage [GO:0120103]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinesin complex [GO:0005871]; membrane [GO:0016020]; microtubule [GO:0005874]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; spindle [GO:0005819]; spindle pole [GO:0000922] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; cytoskeletal motor activity [GO:0003774]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777] 0.96795 -2.872 ATANFGK 0 0 0 0 0 0 0 0 0 0 0 10.0381 0 0 0 0 0 0 0 0 0 0 0 0 10.4366 0 0 O00142 KITM_HUMAN "Thymidine kinase 2, mitochondrial (EC 2.7.1.21) (2'-deoxyuridine kinase TK2) (EC 2.7.1.74) (Deoxycytidine kinase TK2) (EC 2.7.1.-) (Mt-TK)" TK2 Homo sapiens (Human) deoxycytidine metabolic process [GO:0046092]; DNA biosynthetic process [GO:0071897]; nucleobase-containing compound metabolic process [GO:0006139]; phosphorylation [GO:0016310]; pyrimidine nucleoside salvage [GO:0043097]; thymidine metabolic process [GO:0046104] cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; deoxycytidine kinase activity [GO:0004137]; deoxynucleoside kinase activity [GO:0019136]; nucleoside kinase activity [GO:0019206]; thymidine kinase activity [GO:0004797] 0.8836 -0.32053 MLELFEQNRDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.61364 0 0 0 8.89327 O00144 FZD9_HUMAN Frizzled-9 (Fz-9) (hFz9) (FzE6) (CD antigen CD349) FZD9 FZD3 Homo sapiens (Human) B cell differentiation [GO:0030183]; bone regeneration [GO:1990523]; canonical Wnt signaling pathway [GO:0060070]; learning or memory [GO:0007611]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of necroptotic process [GO:0060546]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904394]; nervous system development [GO:0007399]; neuroblast proliferation [GO:0007405]; non-canonical Wnt signaling pathway [GO:0035567]; ossification [GO:0001503]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of neural precursor cell proliferation [GO:2000179]; postsynapse organization [GO:0099173]; regulation of cell cycle [GO:0051726]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of postsynaptic cytosolic calcium ion concentration [GO:0099566]; regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904393]; release of cytochrome c from mitochondria [GO:0001836] cell surface [GO:0009986]; cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; filopodium membrane [GO:0031527]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; mitochondrial membrane [GO:0031966]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794] G protein-coupled receptor activity [GO:0004930]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; Wnt receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147] 0.95202 -1.4449 CGPGVEVFWSRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.53702 0 0 0 0 0 0 0 0 0 0 0 O00155 GPR25_HUMAN Probable G-protein coupled receptor 25 GPR25 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930] 0.76006 0.29319 CAGALLLAGMSVDR 0 0 0 0 0 0 0 10.4414 9.94398 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.88332 0 O00159 MYO1C_HUMAN Unconventional myosin-Ic (Myosin I beta) (MMI-beta) (MMIb) MYO1C Homo sapiens (Human) actin filament organization [GO:0007015]; cellular response to type II interferon [GO:0071346]; chromatin remodeling [GO:0006338]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration by vascular endothelial growth factor signaling pathway [GO:0038089]; positive regulation of cellular response to insulin stimulus [GO:1900078]; positive regulation of histone acetylation [GO:0035066]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; protein targeting to membrane [GO:0006612]; regulation of bicellular tight junction assembly [GO:2000810]; vesicle transport along actin filament [GO:0030050] actin cytoskeleton [GO:0015629]; B-WICH complex [GO:0110016]; basal plasma membrane [GO:0009925]; brush border [GO:0005903]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; filamentous actin [GO:0031941]; lateral plasma membrane [GO:0016328]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; stereocilium membrane [GO:0060171]; unconventional myosin complex [GO:0016461]; vesicle [GO:0031982] actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; cytoskeletal motor activity [GO:0003774]; signaling receptor binding [GO:0005102]; small GTPase binding [GO:0031267] 0.95934 -1.914 LLSVEGSTLREALTHR 0 0 0 10.6999 11.8834 11.341 0 0 0 0 0 0 0 0 0 0 0 0 9.20002 0 0 0 0 0 0 0 0 O00160 MYO1F_HUMAN Unconventional myosin-If (Myosin-Ie) MYO1F Homo sapiens (Human) actin filament organization [GO:0007015]; vesicle transport along actin filament [GO:0030050] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; unconventional myosin complex [GO:0016461]; vesicle [GO:0031982] actin binding [GO:0003779]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; cytoskeletal motor activity [GO:0003774] 0.88749 -0.3535 VSGGGEK 0 0 0 0 0 0 0 0 0 11.8239 0 0 0 0 0 0 0 0 0 0 0 0 9.226 0 0 0 0 O00161 SNP23_HUMAN Synaptosomal-associated protein 23 (SNAP-23) (Vesicle-membrane fusion protein SNAP-23) SNAP23 Homo sapiens (Human) exocytosis [GO:0006887]; histamine secretion by mast cell [GO:0002553]; membrane fusion [GO:0061025]; post-Golgi vesicle-mediated transport [GO:0006892]; protein transport [GO:0015031]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle priming [GO:0016082]; vesicle targeting [GO:0006903] adherens junction [GO:0005912]; azurophil granule [GO:0042582]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; SNARE complex [GO:0031201]; specific granule [GO:0042581]; specific granule membrane [GO:0035579]; synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex [GO:0070032]; tertiary granule membrane [GO:0070821] SNAP receptor activity [GO:0005484]; syntaxin binding [GO:0019905]; syntaxin-1 binding [GO:0017075] 0.96472 -2.6987 ETEKTLTELNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4765 9.50539 0 9.49737 0 0 0 0 0 0 12.4867 0 O00167 EYA2_HUMAN Eyes absent homolog 2 (EC 3.1.3.48) EYA2 EAB1 Homo sapiens (Human) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; DNA repair [GO:0006281]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; mesodermal cell fate specification [GO:0007501]; mitochondrial outer membrane permeabilization [GO:0097345]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; positive regulation of DNA repair [GO:0045739]; protein dephosphorylation [GO:0006470]; striated muscle tissue development [GO:0014706] cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] histone H2AXY142 phosphatase activity [GO:0140793]; magnesium ion binding [GO:0000287]; protein tyrosine phosphatase activity [GO:0004725] 0.897 -0.67428 NNVGGLIGTPKR 0 0 0 0 0 0 0 0 0 9.62886 0 9.89816 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O00178 GTPB1_HUMAN GTP-binding protein 1 (G-protein 1) (GP-1) (GP1) GTPBP1 Homo sapiens (Human) GTP metabolic process [GO:0046039]; immune response [GO:0006955]; positive regulation of mRNA catabolic process [GO:0061014]; signal transduction [GO:0007165]; translational elongation [GO:0006414] cytoplasmic exosome (RNase complex) [GO:0000177]; cytosol [GO:0005829]; membrane [GO:0016020] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; RNA binding [GO:0003723]; translation elongation factor activity [GO:0003746] 0.72187 0.36383 LVFREGRTK 0 0 0 0 0 0 0 0 0 0 9.01995 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7843 0 O00182 LEG9_HUMAN Galectin-9 (Gal-9) (Ecalectin) (Tumor antigen HOM-HD-21) LGALS9 Homo sapiens (Human) "cellular response to type II interferon [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type II interferon production [GO:0032729]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]" collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634] carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936] 0.69728 0.37782 FDENAVVR 0 0 0 0 0 0 0 0 0 11.6236 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9994 O00186 STXB3_HUMAN Syntaxin-binding protein 3 (Platelet Sec1 protein) (PSP) (Protein unc-18 homolog 3) (Unc18-3) (Protein unc-18 homolog C) (Unc-18C) STXBP3 Homo sapiens (Human) brain development [GO:0007420]; cellular response to type II interferon [GO:0071346]; insulin secretion [GO:0030073]; intracellular glucose homeostasis [GO:0001678]; intracellular protein transport [GO:0006886]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of glucose import [GO:0046325]; neurotransmitter secretion [GO:0007269]; neutrophil degranulation [GO:0043312]; platelet aggregation [GO:0070527]; protein to membrane docking [GO:0022615]; response to insulin [GO:0032868]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192] apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; presynapse [GO:0098793]; secretory granule [GO:0030141]; specific granule [GO:0042581]; tertiary granule [GO:0070820] protein-containing complex binding [GO:0044877]; syntaxin binding [GO:0019905]; syntaxin-1 binding [GO:0017075] 0.93024 -1.2393 DRSAEETFQLSRWTPFIK 0 9.18349 0 0 0 14.4184 0 0 0 0 0 14.5512 0 0 0 0 0 0 0 0 0 0 0 0 9.25715 0 0 O00203 AP3B1_HUMAN AP-3 complex subunit beta-1 (Adaptor protein complex AP-3 subunit beta-1) (Adaptor-related protein complex 3 subunit beta-1) (Beta-3A-adaptin) (Clathrin assembly protein complex 3 beta-1 large chain) AP3B1 ADTB3A Homo sapiens (Human) "anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; antigen processing and presentation, exogenous lipid antigen via MHC class Ib [GO:0048007]; blood coagulation [GO:0007596]; cell morphogenesis [GO:0000902]; clathrin-coated vesicle cargo loading, AP-3-mediated [GO:0035654]; establishment of protein localization to mitochondrial membrane involved in mitochondrial fission [GO:0090152]; granulocyte differentiation [GO:0030851]; hematopoietic progenitor cell differentiation [GO:0002244]; homeostasis of number of cells [GO:0048872]; inflammatory response [GO:0006954]; intracellular protein transport [GO:0006886]; intracellular transport [GO:0046907]; intracellular zinc ion homeostasis [GO:0006882]; lung morphogenesis [GO:0060425]; lysosome organization [GO:0007040]; melanosome assembly [GO:1903232]; melanosome organization [GO:0032438]; mRNA transcription by RNA polymerase II [GO:0042789]; platelet dense granule organization [GO:0060155]; positive regulation of NK T cell differentiation [GO:0051138]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to cell surface [GO:0034394]; protein modification process [GO:0036211]; protein targeting to lysosome [GO:0006622]; regulation of catalytic activity [GO:0050790]; respiratory system process [GO:0003016]; single fertilization [GO:0007338]; skin epidermis development [GO:0098773]; spermatogenesis [GO:0007283]; toll-like receptor signaling pathway [GO:0002224]; vesicle-mediated transport [GO:0016192]" AP-3 adaptor complex [GO:0030123]; axon cytoplasm [GO:1904115]; clathrin adaptor complex [GO:0030131]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; Golgi apparatus [GO:0005794]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; mitochondrion [GO:0005739] GTP-dependent protein binding [GO:0030742]; protein phosphatase binding [GO:0019903] 0.96865 -3.3205 DDCFNVNIQPPVGELLLPVAMSEK 0 0 0 0 0 0 0 0 0 0 11.4322 0 0 0 0 0 0 0 10.0501 0 0 0 0 0 0 0 0 O00212 RHOD_HUMAN Rho-related GTP-binding protein RhoD (Rho-related protein HP1) (RhoHP1) RHOD ARHD Homo sapiens (Human) actin filament bundle assembly [GO:0051017]; cell migration [GO:0016477]; focal adhesion assembly [GO:0048041]; lamellipodium assembly [GO:0030032]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266] cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; Golgi membrane [GO:0000139]; mitochondrial outer membrane [GO:0005741]; plasma membrane [GO:0005886] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; guanyl-nucleotide exchange factor activity [GO:0005085] 0.86858 0.04581 TAAQAAGEEAPPGVR 0 0 0 0 0 0 0 0 0 0 0 0 9.58276 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O00213 APBB1_HUMAN Amyloid beta precursor protein binding family B member 1 (Amyloid-beta A4 precursor protein-binding family B member 1) (Protein Fe65) APBB1 FE65 RIR Homo sapiens (Human) apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; chromatin organization [GO:0006325]; DNA damage response [GO:0006974]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein secretion [GO:0050714]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; signal transduction [GO:0007165]; smooth muscle contraction [GO:0006939] cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202] amyloid-beta binding [GO:0001540]; chromatin binding [GO:0003682]; histone binding [GO:0042393]; low-density lipoprotein particle receptor binding [GO:0050750]; proline-rich region binding [GO:0070064]; transcription coactivator activity [GO:0003713]; ubiquitin protein ligase binding [GO:0031625] 0.9227 -0.9426 IMAERRNAR 0 0 0 0 0 0 9.05349 0 0 0 0 0 10.09 10.91 0 0 0 0 0 0 0 0 0 9.80761 0 0 0 O00217 NDUS8_HUMAN "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (EC 7.1.1.2) (Complex I-23kD) (CI-23kD) (NADH-ubiquinone oxidoreductase 23 kDa subunit) (TYKY subunit)" NDUFS8 Homo sapiens (Human) "aerobic respiration [GO:0009060]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]; response to oxidative stress [GO:0006979]" mitochondrial matrix [GO:0005759]; mitochondrial respiratory chain complex I [GO:0005747]; mitochondrion [GO:0005739] "4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]; NADH dehydrogenase (ubiquinone) activity [GO:0008137]" 0.96173 -2.5603 AGPPGGR 0 0 0 0 0 0 0 0 0 0 9.42448 0 8.2758 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O00219 HYAS3_HUMAN Hyaluronan synthase 3 (EC 2.4.1.212) (Hyaluronate synthase 3) (Hyaluronic acid synthase 3) (HA synthase 3) HAS3 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; extracellular matrix assembly [GO:0085029]; extracellular polysaccharide biosynthetic process [GO:0045226]; hyaluronan biosynthetic process [GO:0030213]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of hyaluranon cable assembly [GO:1900106] early endosome [GO:0005769]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; hyaluranon cable [GO:0036117]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886] hyaluronan synthase activity [GO:0050501]; identical protein binding [GO:0042802] 0.91358 -0.75357 CLTETPTK 0 0 0 0 0 0 0 0 0 11.9658 11.3528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O00222 GRM8_HUMAN Metabotropic glutamate receptor 8 (mGluR8) GRM8 GPRC1H MGLUR8 Homo sapiens (Human) "adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway [GO:0007196]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; regulation of synaptic transmission, glutamatergic [GO:0051966]; visual perception [GO:0007601]" plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; glutamate receptor activity [GO:0008066]; group III metabotropic glutamate receptor activity [GO:0001642] 0.96241 -2.4835 DPDLLSNITLGVR 0 0 0 0 0 0 0 0 9.66825 0 0 9.24127 0 0 0 9.37032 0 0 9.73495 0 0 0 0 0 11.2375 11.1433 0 O00231 PSD11_HUMAN 26S proteasome non-ATPase regulatory subunit 11 (26S proteasome regulatory subunit RPN6) (26S proteasome regulatory subunit S9) (26S proteasome regulatory subunit p44.5) PSMD11 Homo sapiens (Human) proteasome assembly [GO:0043248]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; stem cell differentiation [GO:0048863]; ubiquitin-dependent protein catabolic process [GO:0006511] "cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome accessory complex [GO:0022624]; proteasome complex [GO:0000502]; proteasome regulatory particle, lid subcomplex [GO:0008541]; secretory granule lumen [GO:0034774]" structural molecule activity [GO:0005198] 0 3.7182 AAAAVVEFQR 0 0 0 0 0 0 0 0 0 11.7564 0 8.25267 0 0 0 0 10.1158 9.22831 9.1603 0 0 10.3595 0 9.66139 0 0 0 O00238 BMR1B_HUMAN Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293) BMPR1B Homo sapiens (Human) BMP signaling pathway [GO:0030509]; cartilage condensation [GO:0001502]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; central nervous system neuron differentiation [GO:0021953]; chondrocyte development [GO:0002063]; dorsal/ventral pattern formation [GO:0009953]; endochondral bone morphogenesis [GO:0060350]; eye development [GO:0001654]; inflammatory response [GO:0006954]; negative regulation of chondrocyte proliferation [GO:1902731]; osteoblast differentiation [GO:0001649]; ovarian cumulus expansion [GO:0001550]; ovulation cycle [GO:0042698]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cartilage development [GO:0061036]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of gene expression [GO:0010628]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; proteoglycan biosynthetic process [GO:0030166]; retina development in camera-type eye [GO:0060041]; retinal ganglion cell axon guidance [GO:0031290] HFE-transferrin receptor complex [GO:1990712]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] "ATP binding [GO:0005524]; BMP binding [GO:0036122]; BMP receptor activity [GO:0098821]; metal ion binding [GO:0046872]; protein serine/threonine kinase activity [GO:0004674]; SMAD binding [GO:0046332]; transforming growth factor beta receptor activity, type I [GO:0005025]; transmembrane receptor protein serine/threonine kinase activity [GO:0004675]" 0.63105 0.40067 LRPSFPNRWSSDECLR 0 0 11.2861 0 0 0 0 12.5848 0 0 11.4192 11.1495 0 0 0 10.2752 0 0 0 0 0 0 0 0 0 0 0 O00257 CBX4_HUMAN E3 SUMO-protein ligase CBX4 (EC 2.3.2.-) (Chromobox protein homolog 4) (Polycomb 2 homolog) (Pc2) (hPc2) CBX4 Homo sapiens (Human) chromatin organization [GO:0006325]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein sumoylation [GO:0016925] nuclear body [GO:0016604]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PcG protein complex [GO:0031519]; PRC1 complex [GO:0035102] chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; methylated histone binding [GO:0035064]; phosphoprotein binding [GO:0051219]; single-stranded RNA binding [GO:0003727]; SUMO binding [GO:0032183]; SUMO ligase activity [GO:0061665]; SUMO transferase activity [GO:0019789]; transcription cis-regulatory region binding [GO:0000976]; transcription corepressor activity [GO:0003714] 0.15068 1.0209 AAGAEEK 0 0 0 0 0 0 0 0 0 8.91898 9.39547 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O00264 PGRC1_HUMAN Membrane-associated progesterone receptor component 1 (mPR) (Dap1) (IZA) PGRMC1 HPR6.6 PGRMC Homo sapiens (Human) associative learning [GO:0008306]; axon guidance [GO:0007411]; heme biosynthetic process [GO:0006783]; memory [GO:0007613]; modification of synaptic structure [GO:0099563]; negative regulation of synapse organization [GO:1905809]; positive regulation of protein localization to plasma membrane [GO:1903078] cell body [GO:0044297]; endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; smooth endoplasmic reticulum membrane [GO:0030868]; specific granule membrane [GO:0035579]; synapse [GO:0045202] amyloid-beta binding [GO:0001540]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; steroid binding [GO:0005496] 0.0080863 2.0778 FDGVQDPR 0 0 0 0 0 0 0 0 0 10.4357 10.521 10.9953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O00267 SPT5H_HUMAN Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor 160 kDa subunit) (DSIF p160) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (Tat-cotransactivator 1 protein) (Tat-CT1 protein) SUPT5H SPT5 SPT5H Homo sapiens (Human) "negative regulation of DNA-templated transcription, elongation [GO:0032785]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of macroautophagy [GO:0016239]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription elongation by RNA polymerase II [GO:0034243]; transcription elongation by RNA polymerase II [GO:0006368]; transcription elongation-coupled chromatin remodeling [GO:0140673]" DSIF complex [GO:0032044]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; mRNA binding [GO:0003729]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723] 0.95927 -1.7581 ITIMPKHEDLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.46736 0 10.4957 0 0 0 0 0 0 0 0 0 10.9341 O00268 TAF4_HUMAN Transcription initiation factor TFIID subunit 4 (RNA polymerase II TBP-associated factor subunit C) (TBP-associated factor 4) (Transcription initiation factor TFIID 130 kDa subunit) (TAF(II)130) (TAFII-130) (TAFII130) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) TAF4 TAF2C TAF2C1 TAF4A TAFII130 TAFII135 Homo sapiens (Human) DNA-templated transcription initiation [GO:0006352]; histone H3 acetylation [GO:0043966]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; mRNA transcription by RNA polymerase II [GO:0042789]; ovarian follicle development [GO:0001541]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transcription initiation at RNA polymerase II promoter [GO:0006367] chromatin [GO:0000785]; cytosol [GO:0005829]; male germ cell nucleus [GO:0001673]; MLL1 complex [GO:0071339]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor TFIID complex [GO:0005669]; transcription factor TFTC complex [GO:0033276] aryl hydrocarbon receptor binding [GO:0017162]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982] 0.82065 0.21688 ISETAQQK 0 0 0 0 0 0 0 0 0 12.1762 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O00291 HIP1_HUMAN Huntingtin-interacting protein 1 (HIP-1) (Huntingtin-interacting protein I) (HIP-I) HIP1 Homo sapiens (Human) actin filament organization [GO:0007015]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cell differentiation [GO:0030154]; clathrin coat assembly [GO:0048268]; endocytosis [GO:0006897]; neurotransmitter receptor transport [GO:0099637]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of receptor-mediated endocytosis [GO:0048260]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein stabilization [GO:0050821]; regulation of apoptotic process [GO:0042981]; regulation of endocytosis [GO:0030100]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149] clathrin-coated vesicle [GO:0030136]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of postsynaptic membrane [GO:0098890]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleus [GO:0005634]; postsynapse [GO:0098794]; presynapse [GO:0098793]; Schaffer collateral - CA1 synapse [GO:0098685] "actin filament binding [GO:0051015]; AP-2 adaptor complex binding [GO:0035612]; clathrin adaptor activity [GO:0035615]; clathrin binding [GO:0030276]; clathrin light chain binding [GO:0032051]; epidermal growth factor receptor binding [GO:0005154]; glutamate receptor binding [GO:0035254]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; structural constituent of cytoskeleton [GO:0005200]" 0.96946 -6.4788 AQANEQRYSK 0 9.72666 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.56744 0 0 0 0 0 0 0 0 O00299 CLIC1_HUMAN Chloride intracellular channel protein 1 (Chloride channel ABP) (Nuclear chloride ion channel 27) (NCC27) (Regulatory nuclear chloride ion channel protein) (hRNCC) CLIC1 G6 NCC27 Homo sapiens (Human) chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of monoatomic ion transmembrane transport [GO:0034765]; signal transduction [GO:0007165] blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982] cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated monoatomic ion channel activity [GO:0005244] 0 28.358 AEEQPQVELFVK 9.1848 9.11917 8.55144 0 0 0 8.511 0 0 11.0757 11.0242 10.357 0 0 9.53393 0 8.79585 8.83264 11.5657 11.643 11.1006 11.8981 11.9385 11.9037 12.7019 12.5121 12.5116 O00300 TR11B_HUMAN Tumor necrosis factor receptor superfamily member 11B (Osteoclastogenesis inhibitory factor) (Osteoprotegerin) TNFRSF11B OCIF OPG Homo sapiens (Human) apoptotic process [GO:0006915]; extracellular matrix organization [GO:0030198]; negative regulation of bone resorption [GO:0045779]; negative regulation of odontogenesis of dentin-containing tooth [GO:0042489]; negative regulation of osteoclast differentiation [GO:0045671]; response to arsenic-containing substance [GO:0046685]; response to estrogen [GO:0043627]; response to magnesium ion [GO:0032026]; response to nutrient [GO:0007584]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165]; skeletal system development [GO:0001501] extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] cytokine activity [GO:0005125]; signaling receptor activity [GO:0038023] 0.9556 -1.5515 ACKPSDQILKLLSLWR 0 0 0 0 0 0 0 0 0 0 0 0 8.52666 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O00305 CACB4_HUMAN Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4) CACNB4 CACNLB4 Homo sapiens (Human) "adult walking behavior [GO:0007628]; cAMP metabolic process [GO:0046058]; cellular response to leukemia inhibitory factor [GO:1990830]; chemical synaptic transmission [GO:0007268]; detection of light stimulus involved in visual perception [GO:0050908]; gamma-aminobutyric acid secretion [GO:0014051]; gamma-aminobutyric acid signaling pathway [GO:0007214]; muscle cell development [GO:0055001]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; neuromuscular junction development [GO:0007528]; neuronal action potential propagation [GO:0019227]; Peyer's patch development [GO:0048541]; positive regulation of protein localization to nucleolus [GO:1904751]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of voltage-gated calcium channel activity [GO:1901385]; spleen development [GO:0048536]; synaptic transmission, glutamatergic [GO:0035249]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]" cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; synapse [GO:0045202]; voltage-gated calcium channel complex [GO:0005891] protein kinase binding [GO:0019901]; voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels [GO:0099626] 0.89033 -0.4691 GRFHGGK 0 9.80917 0 9.258 9.03546 0 10.1028 0 0 12.7405 0 8.57886 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O00308 WWP2_HUMAN NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 2.3.2.26) (Atrophin-1-interacting protein 2) (AIP2) (HECT-type E3 ubiquitin transferase WWP2) (WW domain-containing protein 2) WWP2 Homo sapiens (Human) extracellular transport [GO:0006858]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein transport [GO:0051224]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transporter activity [GO:0032410]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein modification process [GO:0036211]; protein ubiquitination [GO:0016567]; regulation of membrane potential [GO:0042391]; regulation of monoatomic ion transmembrane transport [GO:0034765]; regulation of potassium ion transmembrane transporter activity [GO:1901016]; transcription by RNA polymerase II [GO:0006366]; viral entry into host cell [GO:0046718] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151] RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription factor binding [GO:0008134]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.96275 -2.1666 ASASSSR 0 0 0 0 0 0 0 0 0 0 0 0 8.626 0 0 0 0 0 0 9.28686 0 0 8.1979 0 0 9.05428 0 O00321 ETV2_HUMAN ETS translocation variant 2 (Ets-related protein 71) ETV2 ER71 ETSRP71 Homo sapiens (Human) blastocyst development [GO:0001824]; blood vessel morphogenesis [GO:0048514]; BMP signaling pathway involved in mesodermal cell fate specification [GO:0060803]; erythrocyte differentiation [GO:0030218]; Notch signaling pathway [GO:0007219]; placenta development [GO:0001890]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of gene expression [GO:0010628]; positive regulation of mesoderm development [GO:2000382]; regulation of transcription by RNA polymerase II [GO:0006357]; Wnt signaling pathway [GO:0016055] nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.941 -1.3156 GLRYYYRR 0 0 0 0 0 0 0 0 0 0 9.63956 0 0 9.55367 0 0 0 0 0 0 0 0 0 0 0 0 0 O00322 UPK1A_HUMAN Uroplakin-1a (UP1a) (Tetraspanin-21) (Tspan-21) (Uroplakin Ia) (UPIa) (UPKa) UPK1A TSPAN21 Homo sapiens (Human) epithelial cell differentiation [GO:0030855] apical plasma membrane urothelial plaque [GO:0120001]; cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] 0.81822 0.21852 VYPLMGVSGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.38409 0 0 0 0 0 0 0 0 O00327 BMAL1_HUMAN Basic helix-loop-helix ARNT-like protein 1 (Aryl hydrocarbon receptor nuclear translocator-like protein 1) (Basic-helix-loop-helix-PAS protein MOP3) (Brain and muscle ARNT-like 1) (Class E basic helix-loop-helix protein 5) (bHLHe5) (Member of PAS protein 3) (PAS domain-containing protein 3) (bHLH-PAS protein JAP3) BMAL1 ARNTL BHLHE5 MOP3 PASD3 Homo sapiens (Human) circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of TOR signaling [GO:0032007]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein acetylation [GO:1901985]; positive regulation of skeletal muscle cell differentiation [GO:2001016]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell cycle [GO:0051726]; regulation of cellular senescence [GO:2000772]; regulation of DNA-templated transcription [GO:0006355]; regulation of hair cycle [GO:0042634]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of type B pancreatic cell development [GO:2000074]; response to redox state [GO:0051775]; spermatogenesis [GO:0007283] chromatin [GO:0000785]; chromatoid body [GO:0033391]; CLOCK-BMAL transcription complex [GO:1990513]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605] "aryl hydrocarbon receptor binding [GO:0017162]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription factor binding [GO:0140297]; E-box binding [GO:0070888]; Hsp90 protein binding [GO:0051879]; protein dimerization activity [GO:0046983]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]" 0.12143 1.0718 DDPHGRLEYTEHQGR 0 0 12.1307 0 11.8358 11.4357 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.55949 O00330 ODPX_HUMAN "Pyruvate dehydrogenase protein X component, mitochondrial (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (E3-binding protein) (E3BP) (Lipoyl-containing pyruvate dehydrogenase complex component X) (proX)" PDHX PDX1 Homo sapiens (Human) acetyl-CoA biosynthetic process from pyruvate [GO:0006086] mitochondrial matrix [GO:0005759]; mitochondrial pyruvate dehydrogenase complex [GO:0005967]; mitochondrion [GO:0005739]; pyruvate dehydrogenase complex [GO:0045254] acyltransferase activity [GO:0016746] 0.80532 0.23667 VVDDELATR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.74977 0 0 0 0 0 O00337 S28A1_HUMAN Sodium/nucleoside cotransporter 1 (Concentrative nucleoside transporter 1) (CNT 1) (hCNT1) (Na(+)/nucleoside cotransporter 1) (Sodium-coupled nucleoside transporter 1) (Solute carrier family 28 member 1) SLC28A1 CNT1 Homo sapiens (Human) azole transmembrane transport [GO:0045117]; cytidine transport [GO:0015861]; import across plasma membrane [GO:0098739]; nucleoside transmembrane transport [GO:1901642]; purine nucleobase transmembrane transport [GO:1904823]; pyrimidine nucleobase transport [GO:0015855]; pyrimidine-containing compound transmembrane transport [GO:0072531]; uridine transport [GO:0015862] apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886] azole transmembrane transporter activity [GO:1901474]; cytidine transmembrane transporter activity [GO:0015212]; nucleoside:sodium symporter activity [GO:0005415]; purine nucleobase transmembrane transporter activity [GO:0005345]; pyrimidine- and adenosine-specific:sodium symporter activity [GO:0015389]; uridine transmembrane transporter activity [GO:0015213] 0.21557 0.89742 LAGAEEWVGDRK 0 0 0 0 0 0 10.0369 0 0 0 0 0 0 0 0 0 0 0 8.93109 0 9.14914 0 9.17385 9.99379 0 0 0 O00338 ST1C2_HUMAN Sulfotransferase 1C2 (ST1C2) (EC 2.8.2.1) (Sulfotransferase 1C1) (SULT1C#1) (humSULTC2) SULT1C2 SULT1C1 Homo sapiens (Human) amine metabolic process [GO:0009308]; sulfation [GO:0051923] cytoplasm [GO:0005737]; cytosol [GO:0005829]; lysosome [GO:0005764] aryl sulfotransferase activity [GO:0004062]; sulfotransferase activity [GO:0008146] 0.92326 -1.0804 FLYVARNAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.7304 0 0 0 0 0 0 10.9272 0 O00341 EAA5_HUMAN Excitatory amino acid transporter 5 (Retinal glutamate transporter) (Solute carrier family 1 member 7) SLC1A7 EAAT5 Homo sapiens (Human) chloride transmembrane transport [GO:1902476]; dicarboxylic acid transport [GO:0006835]; L-glutamate transmembrane transport [GO:0015813]; monoatomic ion transport [GO:0006811]; neurotransmitter transport [GO:0006836]; neurotransmitter uptake [GO:0001504] plasma membrane [GO:0005886]; postsynapse [GO:0098794]; synaptic membrane [GO:0097060] extracellularly glutamate-gated chloride channel activity [GO:0008068]; glutamate:sodium symporter activity [GO:0015501]; high-affinity L-glutamate transmembrane transporter activity [GO:0005314]; L-glutamate transmembrane transporter activity [GO:0005313]; neutral L-amino acid transmembrane transporter activity [GO:0015175] 0.87852 0.012178 LSPQEISYFQFPGELLMR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4215 0 O00370 LORF2_HUMAN LINE-1 retrotransposable element ORF2 protein (ORF2p) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Homo sapiens (Human) DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; retrotransposition [GO:0032197] metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; type II site-specific deoxyribonuclease activity [GO:0009036] 0.96757 -3.7133 EIETQKTLQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.66051 0 0 0 9.44305 0 0 9.50245 0 0 O00391 QSOX1_HUMAN Sulfhydryl oxidase 1 (hQSOX) (EC 1.8.3.2) (Quiescin Q6) QSOX1 QSCN6 UNQ2520/PRO6013 Homo sapiens (Human) extracellular matrix assembly [GO:0085029]; negative regulation of macroautophagy [GO:0016242]; protein folding [GO:0006457] endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intercellular bridge [GO:0045171]; intracellular membrane-bounded organelle [GO:0043231]; platelet alpha granule lumen [GO:0031093]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724] FAD binding [GO:0071949]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide isomerase activity [GO:0003756] 0.90531 -0.72148 LEEIDGFFAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.5451 0 10.418 0 O00401 WASL_HUMAN Actin nucleation-promoting factor WASL (Neural Wiskott-Aldrich syndrome protein) (N-WASP) WASL Homo sapiens (Human) actin filament polymerization [GO:0030041]; actin polymerization or depolymerization [GO:0008154]; cell division [GO:0051301]; dendritic spine morphogenesis [GO:0060997]; negative regulation of lymphocyte migration [GO:2000402]; negative regulation of membrane tubulation [GO:1903526]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein-containing complex assembly [GO:0065003]; protein-containing complex localization [GO:0031503]; regulation of postsynapse organization [GO:0099175]; regulation of protein localization [GO:0032880]; response to bacterium [GO:0009617]; spindle localization [GO:0051653]; vesicle budding from membrane [GO:0006900]; vesicle organization [GO:0016050]; vesicle transport along actin filament [GO:0030050] actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; lamellipodium [GO:0030027]; nucleus [GO:0005634]; plasma membrane [GO:0005886] actin binding [GO:0003779]; GTPase regulator activity [GO:0030695]; microtubule binding [GO:0008017] 0.72809 0.3443 VIYDFIEK 0 0 0 0 11.366 0 12.8668 0 0 0 0 0 0 0 11.2886 0 11.45 0 0 0 0 0 0 0 0 0 0 O00408 PDE2A_HUMAN "cGMP-dependent 3',5'-cyclic phosphodiesterase (EC 3.1.4.17) (Cyclic GMP-stimulated phosphodiesterase) (CGS-PDE) (cGSPDE)" PDE2A Homo sapiens (Human) "adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to xenobiotic stimulus [GO:0071466]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of cGMP-mediated signaling [GO:0010752]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; synaptic membrane [GO:0097060] "3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]" 0.96402 -2.386 FCLMVKK 0 15.4896 0 11.6484 0 11.5868 0 0 15.0809 0 0 0 13.7688 13.6753 13.6705 0 13.5282 0 0 0 0 10.5983 0 0 0 0 10.3626 O00410 IPO5_HUMAN Importin-5 (Imp5) (Importin subunit beta-3) (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5) IPO5 KPNB3 RANBP5 Homo sapiens (Human) cellular response to amino acid stimulus [GO:0071230]; cytosolic pattern recognition receptor signaling pathway [GO:0002753]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of protein import into nucleus [GO:0042307]; protein import into nucleus [GO:0006606]; ribosomal protein import into nucleus [GO:0006610] cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] GTPase inhibitor activity [GO:0005095]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; RNA binding [GO:0003723]; small GTPase binding [GO:0031267] 0.95431 -1.5313 AKLEEHFK 0 0 9.09487 0 14.2731 0 0 0 0 0 0 0 0 0 13.3295 0 0 0 0 0 0 0 0 9.95883 10.7683 0 0 O00418 EF2K_HUMAN Eukaryotic elongation factor 2 kinase (eEF-2 kinase) (eEF-2K) (EC 2.7.11.20) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase) EEF2K Homo sapiens (Human) cellular response to anoxia [GO:0071454]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to insulin stimulus [GO:0032869]; myosin II filament disassembly [GO:0031037]; negative regulation of apoptotic process [GO:0043066]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of endocytosis [GO:0045807]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of protein autophosphorylation [GO:0031952]; regulation of translation at postsynapse [GO:0140245]; response to ischemia [GO:0002931]; response to prolactin [GO:1990637]; translational elongation [GO:0006414] cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; postsynaptic density [GO:0014069] "ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; elongation factor-2 kinase activity [GO:0004686]; protein kinase activity [GO:0004672]; translation factor activity, RNA binding [GO:0008135]" 0.76468 0.28629 LANQYYQK 0 0 0 0 0 0 9.06318 0 0 0 0 0 0 0 0 0 0 0 0 0 9.35542 0 0 0 0 0 0 O00422 SAP18_HUMAN Histone deacetylase complex subunit SAP18 (18 kDa Sin3-associated polypeptide) (2HOR0202) (Cell growth-inhibiting gene 38 protein) (Sin3-associated polypeptide p18) SAP18 GIG38 Homo sapiens (Human) "mRNA processing [GO:0006397]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of apoptotic process [GO:0043065]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA splicing [GO:0008380]" ASAP complex [GO:0061574]; cytosol [GO:0005829]; histone deacetylase complex [GO:0000118]; nuclear body [GO:0016604]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714] 0.95973 -1.9296 ELTSLVKEVYPEAR 0 0 0 0 0 0 8.85857 0 0 0 0 0 0 0 0 10.3199 0 0 0 0 0 10.8234 0 0 0 0 0 O00423 EMAL1_HUMAN Echinoderm microtubule-associated protein-like 1 (EMAP-1) (HuEMAP-1) EML1 EMAP1 EMAPL EMAPL1 Homo sapiens (Human) brain development [GO:0007420]; hematopoietic progenitor cell differentiation [GO:0002244]; microtubule cytoskeleton organization [GO:0000226]; mitotic spindle organization [GO:0007052]; neuroblast proliferation [GO:0007405] cytosol [GO:0005829]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; mitotic spindle midzone [GO:1990023]; mitotic spindle pole [GO:0097431]; perinuclear region of cytoplasm [GO:0048471] calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; tubulin binding [GO:0015631] 0.88431 -0.14074 AVTCIAFSK 0 0 0 0 0 0 0 9.71125 0 0 0 0 0 0 0 0 15.0813 0 0 0 0 0 0 0 0 0 0 O00442 RTCA_HUMAN RNA 3'-terminal phosphate cyclase (RNA cyclase) (RNA-3'-phosphate cyclase) (EC 6.5.1.4) (RNA terminal phosphate cyclase domain-containing protein 1) (RTC domain-containing protein 1) RTCA RPC RPC1 RTC1 RTCD1 Homo sapiens (Human) RNA processing [GO:0006396] nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; RNA binding [GO:0003723]; RNA-3'-phosphate cyclase activity [GO:0003963] 0.60832 0.43068 DLCDGQLEGAEIGSTEITFTPEK 12.7525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O00443 P3C2A_HUMAN Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (PI3K-C2-alpha) (PtdIns-3-kinase C2 subunit alpha) (EC 2.7.1.137) (EC 2.7.1.153) (EC 2.7.1.154) (Phosphoinositide 3-kinase-C2-alpha) PIK3C2A Homo sapiens (Human) cell migration [GO:0016477]; clathrin coat assembly [GO:0048268]; endocytosis [GO:0006897]; epidermal growth factor receptor signaling pathway [GO:0007173]; exocytosis [GO:0006887]; insulin receptor signaling pathway [GO:0008286]; membrane organization [GO:0061024]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of autophagy [GO:0010508]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; vascular associated smooth muscle contraction [GO:0014829] clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; phosphatidylinositol 3-kinase complex [GO:0005942]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; vesicle [GO:0031982] "1-phosphatidylinositol-3-kinase activity [GO:0016303]; 1-phosphatidylinositol-4-phosphate 3-kinase activity [GO:0035005]; ATP binding [GO:0005524]; clathrin binding [GO:0030276]; phosphatidylinositol 3-kinase activity [GO:0035004]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-3,4-bisphosphate 5-kinase activity [GO:0052812]; phosphatidylinositol-4,5-bisphosphate 3-kinase activity [GO:0046934]" 0.96893 -5.8397 IASTSEFLKNGK 0 0 0 10.099 0 0 0 8.85428 0 0 0 9.44491 0 0 0 0 0 0 0 0 9.12184 0 10.5621 0 0 0 0 O00444 PLK4_HUMAN Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak) PLK4 SAK STK18 Homo sapiens (Human) centriole replication [GO:0007099]; cilium assembly [GO:0060271]; de novo centriole assembly involved in multi-ciliated epithelial cell differentiation [GO:0098535]; positive regulation of centriole replication [GO:0046601]; protein phosphorylation [GO:0006468]; trophoblast giant cell differentiation [GO:0060707] centriole [GO:0005814]; centrosome [GO:0005813]; cleavage furrow [GO:0032154]; cytosol [GO:0005829]; deuterosome [GO:0098536]; nucleolus [GO:0005730]; procentriole [GO:0120098]; procentriole replication complex [GO:0120099]; XY body [GO:0001741] ATP binding [GO:0005524]; identical protein binding [GO:0042802]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.95929 -1.7399 DLIHQLLR 0 0 0 0 0 0 0 10.2085 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O00445 SYT5_HUMAN Synaptotagmin-5 (Synaptotagmin V) (SytV) SYT5 Homo sapiens (Human) calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cellular response to calcium ion [GO:0071277]; chemical synaptic transmission [GO:0007268]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; synaptic vesicle endocytosis [GO:0048488] axon [GO:0030424]; dense core granule [GO:0031045]; neuronal cell body [GO:0043025]; neuronal dense core vesicle membrane [GO:0099012]; perinuclear region of cytoplasm [GO:0048471]; proximal neuron projection [GO:1990769]; recycling endosome membrane [GO:0055038]; synaptic vesicle membrane [GO:0030672] "calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; clathrin binding [GO:0030276]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; protein heterodimerization activity [GO:0046982]; syntaxin binding [GO:0019905]" 0.96016 -1.9009 VLVMAVYDFDRFSR 0 0 9.11982 0 0 0 0 0 0 0 9.84166 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O00451 GFRA2_HUMAN GDNF family receptor alpha-2 (GDNF receptor alpha-2) (GDNFR-alpha-2) (GFR-alpha-2) (GDNF receptor beta) (GDNFR-beta) (Neurturin receptor alpha) (NRTNR-alpha) (NTNR-alpha) (RET ligand 2) (TGF-beta-related neurotrophic factor receptor 2) GFRA2 GDNFRB RETL2 TRNR2 Homo sapiens (Human) nervous system development [GO:0007399]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] external side of plasma membrane [GO:0009897]; extrinsic component of membrane [GO:0019898]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] glial cell-derived neurotrophic factor receptor activity [GO:0016167] 0.95329 -1.4878 ALRQFFDR 0 0 0 0 0 9.4055 0 0 0 0 9.83562 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O00458 IFRD1_HUMAN Interferon-related developmental regulator 1 (Nerve growth factor-inducible protein PC4) IFRD1 Homo sapiens (Human) muscle cell differentiation [GO:0042692]; myoblast fate determination [GO:0007518]; negative regulation of axon extension [GO:0030517]; negative regulation of collateral sprouting [GO:0048671]; skeletal muscle tissue regeneration [GO:0043403]; striated muscle tissue development [GO:0014706] nucleus [GO:0005634]; sarcoplasm [GO:0016528] 0.82949 0.20611 MTLTDSIER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.76658 0 0 0 0 0 0 0 0 0 0 0 0 O00461 GOLI4_HUMAN "Golgi integral membrane protein 4 (Golgi integral membrane protein, cis) (GIMPc) (Golgi phosphoprotein 4) (Golgi-localized phosphoprotein of 130 kDa) (Golgi phosphoprotein of 130 kDa)" GOLIM4 GIMPC GOLPH4 GPP130 Homo sapiens (Human) cis-Golgi network [GO:0005801]; endocytic vesicle [GO:0030139]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; transport vesicle [GO:0030133] 0.91869 -0.87876 AEDTKLYAPTHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.54597 9.71829 0 0 0 0 0 0 0 0 10.5315 0 0 O00463 TRAF5_HUMAN TNF receptor-associated factor 5 (RING finger protein 84) TRAF5 RNF84 Homo sapiens (Human) apoptotic process [GO:0006915]; interleukin-17-mediated signaling pathway [GO:0097400]; mRNA stabilization [GO:0048255]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of JNK cascade [GO:0046330]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; signal transduction [GO:0007165]; signal transduction involved in regulation of gene expression [GO:0023019]; tumor necrosis factor-mediated signaling pathway [GO:0033209] CD40 receptor complex [GO:0035631]; centrosome [GO:0005813]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829] identical protein binding [GO:0042802]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270] 0.96808 -2.9177 CGYRLCAR 0 0 0 0 0 0 0 11.8199 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O00468 AGRIN_HUMAN Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)] AGRN AGRIN Homo sapiens (Human) clustering of voltage-gated sodium channels [GO:0045162]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic assembly at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; signal transduction [GO:0007165]; synapse organization [GO:0050808] basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; lysosomal lumen [GO:0043202]; plasma membrane [GO:0005886]; synapse [GO:0045202] calcium ion binding [GO:0005509]; chondroitin sulfate binding [GO:0035374]; dystroglycan binding [GO:0002162]; heparan sulfate proteoglycan binding [GO:0043395]; laminin binding [GO:0043236]; sialic acid binding [GO:0033691]; structural constituent of cytoskeleton [GO:0005200] 0.96948 -4.0369 DFLALALLDGRVQLR 0 0 0 0 10.0074 0 11.9896 0 0 0 0 0 0 9.69133 10.6162 0 0 0 0 0 0 0 0 0 10.6564 0 0 O00469 PLOD2_HUMAN "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 (EC 1.14.11.4) (Lysyl hydroxylase 2) (LH2)" PLOD2 Homo sapiens (Human) hydroxylysine biosynthetic process [GO:0046947]; peptidyl-lysine hydroxylation [GO:0017185]; protein modification process [GO:0036211]; response to hypoxia [GO:0001666] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; rough endoplasmic reticulum membrane [GO:0030867] iron ion binding [GO:0005506]; L-ascorbic acid binding [GO:0031418]; procollagen-lysine 5-dioxygenase activity [GO:0008475] 0.95494 -1.5368 DIKVFFDK 0 10.9714 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.20271 0 0 0 0 0 0 0 0 O00471 EXOC5_HUMAN Exocyst complex component 5 (Exocyst complex component Sec10) (hSec10) EXOC5 SEC10 SEC10L1 Homo sapiens (Human) epithelial cell apoptotic process [GO:1904019]; establishment of planar polarity [GO:0001736]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; membrane fission [GO:0090148]; mitotic cytokinesis [GO:0000281]; non-motile cilium assembly [GO:1905515]; post-Golgi vesicle-mediated transport [GO:0006892]; protein localization to plasma membrane [GO:0072659]; protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904]; vesicle tethering involved in exocytosis [GO:0090522] cytoplasm [GO:0005737]; cytosol [GO:0005829]; exocyst [GO:0000145]; midbody [GO:0030496] small GTPase binding [GO:0031267] 0.96714 -2.8626 AVEAQKLMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.72523 0 0 9.25781 0 0 0 0 O00472 ELL2_HUMAN RNA polymerase II elongation factor ELL2 ELL2 Homo sapiens (Human) positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription elongation by RNA polymerase II [GO:0006368] nucleoplasm [GO:0005654]; transcription elongation factor complex [GO:0008023] cis-regulatory region sequence-specific DNA binding [GO:0000987] 0.51947 0.59812 DLSYTLK 0 0 0 0 0 0 0 0 0 10.1097 10.5083 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O00478 BT3A3_HUMAN Butyrophilin subfamily 3 member A3 BTN3A3 BTF3 Homo sapiens (Human) regulation of cytokine production [GO:0001817]; T cell mediated immunity [GO:0002456]; T cell receptor signaling pathway [GO:0050852] external side of plasma membrane [GO:0009897]; membrane [GO:0016020]; plasma membrane [GO:0005886] signaling receptor binding [GO:0005102] 0.96733 -2.8204 IALSRETERER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2586 O00479 HMGN4_HUMAN High mobility group nucleosome-binding domain-containing protein 4 (Non-histone chromosomal protein HMG-17-like 3) (Non-histone chromosomal protein) HMGN4 HMG17L3 NHC Homo sapiens (Human) chromatin organization [GO:0006325] chromatin [GO:0000785]; nucleus [GO:0005634] chromatin binding [GO:0003682]; nucleosomal DNA binding [GO:0031492] 0.94137 -1.316 ADAGKDGNNPAKNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4466 0 0 0 0 O00481 BT3A1_HUMAN Butyrophilin subfamily 3 member A1 (CD antigen CD277) BTN3A1 BTF5 Homo sapiens (Human) activated T cell proliferation [GO:0050798]; adaptive immune response [GO:0002250]; positive regulation of cytokine production [GO:0001819]; positive regulation of type II interferon production [GO:0032729]; regulation of cytokine production [GO:0001817]; T cell receptor signaling pathway [GO:0050852] external side of plasma membrane [GO:0009897]; plasma membrane [GO:0005886] signaling receptor binding [GO:0005102] 0.8856 -0.33294 WRSIQYASR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3996 0 0 0 0 0 0 0 O00482 NR5A2_HUMAN Nuclear receptor subfamily 5 group A member 2 (Alpha-1-fetoprotein transcription factor) (B1-binding factor) (hB1F) (CYP7A promoter-binding factor) (Hepatocytic transcription factor) (Liver receptor homolog 1) (LRH-1) NR5A2 B1F CPF FTF Homo sapiens (Human) acinar cell differentiation [GO:0090425]; bile acid metabolic process [GO:0008206]; calcineurin-mediated signaling [GO:0097720]; cellular response to leukemia inhibitory factor [GO:1990830]; cholesterol homeostasis [GO:0042632]; embryo development ending in birth or egg hatching [GO:0009792]; homeostatic process [GO:0042592]; hormone-mediated signaling pathway [GO:0009755]; pancreas morphogenesis [GO:0061113]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of viral genome replication [GO:0045070]; regulation of cell population proliferation [GO:0042127]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; tissue development [GO:0009888] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575] "chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; nuclear receptor activity [GO:0004879]; phospholipid binding [GO:0005543]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]; transcription coregulator binding [GO:0001221]; zinc ion binding [GO:0008270]" 0.96267 -2.5016 FGPMYKRDR 0 0 0 0 0 0 0 0 0 0 8.99842 0 0 10.6958 0 0 0 0 0 0 0 9.79534 0 0 0 0 0 O00499 BIN1_HUMAN Myc box-dependent-interacting protein 1 (Amphiphysin II) (Amphiphysin-like protein) (Box-dependent myc-interacting protein 1) (Bridging integrator 1) BIN1 AMPHL Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endocytosis [GO:0006897]; endosome to lysosome transport [GO:0008333]; lipid tube assembly [GO:0060988]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902960]; negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1904878]; negative regulation of potassium ion transmembrane transport [GO:1901380]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of ventricular cardiac muscle cell action potential [GO:1903946]; nucleus localization [GO:0051647]; nucleus organization [GO:0006997]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of apoptotic process [GO:0043065]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of endocytosis [GO:0045807]; positive regulation of GTPase activity [GO:0043547]; regulation of cell cycle process [GO:0010564]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of neuron differentiation [GO:0045664]; synaptic vesicle endocytosis [GO:0048488]; T-tubule organization [GO:0033292] actin cytoskeleton [GO:0015629]; axon [GO:0030424]; axon initial segment [GO:0043194]; axon terminus [GO:0043679]; cerebellar mossy fiber [GO:0044300]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome [GO:0005768]; extrinsic component of synaptic vesicle membrane [GO:0098850]; glutamatergic synapse [GO:0098978]; I band [GO:0031674]; lipid tube [GO:0060987]; membrane [GO:0016020]; node of Ranvier [GO:0033268]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; RNA polymerase II transcription repressor complex [GO:0090571]; synaptic vesicle [GO:0008021]; T-tubule [GO:0030315]; varicosity [GO:0043196]; vesicle [GO:0031982]; Z disc [GO:0030018] actin filament binding [GO:0051015]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; clathrin binding [GO:0030276]; GTPase binding [GO:0051020]; identical protein binding [GO:0042802]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]; protein-folding chaperone binding [GO:0051087]; RNA polymerase binding [GO:0070063]; tau protein binding [GO:0048156] 0.82986 0.20688 QHGSNTFTVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5941 0 0 0 0 0 8.93558 0 0 0 0 O00506 STK25_HUMAN Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1) STK25 SOK1 YSK1 Homo sapiens (Human) axonogenesis [GO:0007409]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Golgi localization [GO:0051645]; Golgi reassembly [GO:0090168]; intrinsic apoptotic signaling pathway in response to hydrogen peroxide [GO:0036481]; positive regulation of axonogenesis [GO:0050772]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; response to hydrogen peroxide [GO:0042542]; response to oxidative stress [GO:0006979]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.90756 -0.73276 FRPTAKELLK 8.75375 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O00515 LAD1_HUMAN Ladinin-1 (Lad-1) (Linear IgA disease antigen) (LADA) LAD1 LAD Homo sapiens (Human) actin cytoskeleton [GO:0015629]; basement membrane [GO:0005604]; extracellular exosome [GO:0070062] cadherin binding [GO:0045296]; structural molecule activity [GO:0005198] 0.92029 -0.91737 AEPASSR 0 0 0 0 0 0 0 0 0 8.8885 0 0 0 0 0 0 0 0 0 0 0 9.78594 0 0 0 0 10.4606 O00519 FAAH1_HUMAN Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Fatty acid ester hydrolase) (EC 3.1.1.-) (Oleamide hydrolase 1) FAAH FAAH1 Homo sapiens (Human) arachidonic acid metabolic process [GO:0019369]; fatty acid catabolic process [GO:0009062]; monoacylglycerol catabolic process [GO:0052651]; positive regulation of vasoconstriction [GO:0045907] cytoskeleton [GO:0005856]; endoplasmic reticulum membrane [GO:0005789]; organelle membrane [GO:0031090] acylglycerol lipase activity [GO:0047372]; amidase activity [GO:0004040]; fatty acid amide hydrolase activity [GO:0017064]; identical protein binding [GO:0042802]; phospholipid binding [GO:0005543] 0.93223 -1.2668 DVESLALCLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3704 0 0 0 0 0 0 0 O00522 KRIT1_HUMAN Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein) KRIT1 CCM1 Homo sapiens (Human) angiogenesis [GO:0001525]; cell redox homeostasis [GO:0045454]; endothelium development [GO:0003158]; integrin activation [GO:0033622]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of protein binding [GO:0032092]; regulation of angiogenesis [GO:0045765]; regulation of establishment of cell polarity [GO:2000114]; small GTPase mediated signal transduction [GO:0007264] cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] "GTPase regulator activity [GO:0030695]; microtubule binding [GO:0008017]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]" 0.95907 -1.7373 ILHEYKNLSTSEGVSK 0 8.86771 0 0 0 0 9.6476 0 0 0 0 0 0 0 0 0 9.24817 0 0 0 0 0 10.4756 0 10.227 0 11.01 O00533 NCHL1_HUMAN Neural cell adhesion molecule L1-like protein (Close homolog of L1) [Cleaved into: Processed neural cell adhesion molecule L1-like protein] CHL1 CALL Homo sapiens (Human) adult locomotory behavior [GO:0008344]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cognition [GO:0050890]; exploration behavior [GO:0035640]; negative regulation of neuron apoptotic process [GO:0043524]; neuron migration [GO:0001764]; signal transduction [GO:0007165] apical part of cell [GO:0045177]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886] protease binding [GO:0002020] 0.88366 -0.056503 IIPSNNSGTFR 0 0 0 0 0 0 0 0 0 0 0 8.75412 0 0 0 0 0 0 0 9.99972 9.67675 9.8265 0 0 0 0 0 O00534 VMA5A_HUMAN von Willebrand factor A domain-containing protein 5A (Breast cancer suppressor candidate 1) (BCSC-1) (Loss of heterozygosity 11 chromosomal region 2 gene A protein) VWA5A BCSC1 LOH11CR2A Homo sapiens (Human) nucleoplasm [GO:0005654] 0.89838 -0.59322 DMGLRETPASDK 13.3389 0 0 10.4676 11.1362 10.863 13.3455 0 0 12.7309 12.4253 12.9697 0 11.6634 0 0 0 0 0 0 0 0 0 0 0 0 0 O00541 PESC_HUMAN Pescadillo homolog PES1 Homo sapiens (Human) "cell population proliferation [GO:0008283]; maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; regulation of cell cycle [GO:0051726]; ribosomal large subunit biogenesis [GO:0042273]; rRNA processing [GO:0006364]" "chromosome [GO:0005694]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; PeBoW complex [GO:0070545]; preribosome, large subunit precursor [GO:0030687]" ribonucleoprotein complex binding [GO:0043021]; RNA binding [GO:0003723] 0.5966 0.44476 LAALEEQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.8952 0 0 O00555 CAC1A_HUMAN "Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Brain calcium channel I) (BI) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Voltage-gated calcium channel subunit alpha Cav2.1)" CACNA1A CACH4 CACN3 CACNL1A4 Homo sapiens (Human) calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; cellular response to amyloid-beta [GO:1904646]; chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; regulation of monoatomic ion transmembrane transport [GO:0034765]; response to amyloid-beta [GO:1904645] cell projection [GO:0042995]; cytoplasm [GO:0005737]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; voltage-gated calcium channel complex [GO:0005891] amyloid-beta binding [GO:0001540]; high voltage-gated calcium channel activity [GO:0008331]; metal ion binding [GO:0046872]; syntaxin binding [GO:0019905]; voltage-gated calcium channel activity [GO:0005245] 0.9691 -3.4813 DPSGSAGLDAR 10.9638 0 0 10.0242 0 0 0 0 0 0 0 0 0 0 0 0 0 9.54139 10.212 0 0 0 0 0 0 0 0 O00566 MPP10_HUMAN U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10) MPHOSPH10 MPP10 Homo sapiens (Human) "maturation of SSU-rRNA [GO:0030490]; ribosomal small subunit biogenesis [GO:0042274]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]" chromosome [GO:0005694]; Mpp10 complex [GO:0034457]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040]; sno(s)RNA-containing ribonucleoprotein complex [GO:0005732] RNA binding [GO:0003723] 0.91419 -0.82675 DQAWDDVVRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.45492 0 O00567 NOP56_HUMAN Nucleolar protein 56 (Nucleolar protein 5A) NOP56 NOL5A Homo sapiens (Human) ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364] box C/D RNP complex [GO:0031428]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; pre-snoRNP complex [GO:0070761]; small-subunit processome [GO:0032040]; sno(s)RNA-containing ribonucleoprotein complex [GO:0005732] cadherin binding [GO:0045296]; histone methyltransferase binding [GO:1990226]; RNA binding [GO:0003723]; snoRNA binding [GO:0030515] 0.81906 0.21847 LLLETHLPSK 0 0 0 0 0 0 0 0 12.6359 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O00571 DDX3X_HUMAN "ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (CAP-Rf) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (DBX) (Helicase-like protein 2) (HLP2)" DDX3X DBX DDX3 Homo sapiens (Human) cell differentiation [GO:0030154]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to osmotic stress [GO:0071470]; cellular response to virus [GO:0098586]; chromosome segregation [GO:0007059]; cytosolic ribosome assembly [GO:0042256]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; gamete generation [GO:0007276]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway [GO:0097193]; lipid homeostasis [GO:0055088]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of translation [GO:0017148]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of chemokine (C-C motif) ligand 5 production [GO:0071651]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227]; positive regulation of protein acetylation [GO:1901985]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of translation in response to endoplasmic reticulum stress [GO:0036493]; positive regulation of translational initiation [GO:0045948]; positive regulation of type I interferon production [GO:0032481]; positive regulation of viral genome replication [GO:0045070]; primary miRNA processing [GO:0031053]; protein localization to cytoplasmic stress granule [GO:1903608]; response to virus [GO:0009615]; RNA secondary structure unwinding [GO:0010501]; stress granule assembly [GO:0034063]; translational initiation [GO:0006413]; Wnt signaling pathway [GO:0016055] cell leading edge [GO:0031252]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lamellipodium [GO:0030027]; NLRP3 inflammasome complex [GO:0072559]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P granule [GO:0043186]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; cadherin binding [GO:0045296]; CTPase activity [GO:0043273]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; eukaryotic initiation factor 4E binding [GO:0008190]; gamma-tubulin binding [GO:0043015]; GTPase activity [GO:0003924]; mRNA 5'-UTR binding [GO:0048027]; mRNA binding [GO:0003729]; poly(A) binding [GO:0008143]; primary miRNA binding [GO:0070878]; protein serine/threonine kinase activator activity [GO:0043539]; ribonucleoside triphosphate phosphatase activity [GO:0017111]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA stem-loop binding [GO:0035613]; RNA strand annealing activity [GO:0033592]; signaling adaptor activity [GO:0035591]; transcription factor binding [GO:0008134]; translation initiation factor binding [GO:0031369] 0.95457 -1.503 EATKGFYDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.61802 0 0 0 0 0 0 0 0 0 O00602 FCN1_HUMAN Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) FCN1 FCNM Homo sapiens (Human) "cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of opsonization [GO:1903028]; protein localization to cell surface [GO:0034394]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654]" collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; serine-type endopeptidase complex [GO:1905370] carbohydrate binding [GO:0030246]; G protein-coupled receptor binding [GO:0001664]; metal ion binding [GO:0046872]; pattern recognition receptor activity [GO:0038187]; sialic acid binding [GO:0033691]; signaling receptor binding [GO:0005102] 0.16445 0.98922 AGPVGPK 0 0 0 9.48862 0 0 9.27984 0 0 0 0 0 10.0562 10.6714 10.4986 0 10.6344 10.8835 0 0 0 0 0 0 0 0 0 O00622 CCN1_HUMAN CCN family member 1 (Cellular communication network factor 1) (Cysteine-rich angiogenic inducer 61) (Insulin-like growth factor-binding protein 10) (IBP-10) (IGF-binding protein 10) (IGFBP-10) (Protein CYR61) (Protein GIG1) CCN1 CYR61 GIG1 IGFBP10 Homo sapiens (Human) "apoptotic process involved in heart morphogenesis [GO:0003278]; atrial septum morphogenesis [GO:0060413]; atrioventricular valve morphogenesis [GO:0003181]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; chorio-allantoic fusion [GO:0060710]; extracellular matrix organization [GO:0030198]; intussusceptive angiogenesis [GO:0002041]; labyrinthine layer blood vessel development [GO:0060716]; negative regulation of apoptotic process [GO:0043066]; osteoblast differentiation [GO:0001649]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cartilage development [GO:0061036]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; reactive oxygen species metabolic process [GO:0072593]; regulation of ERK1 and ERK2 cascade [GO:0070372]; signal transduction [GO:0007165]; ventricular septum development [GO:0003281]; wound healing, spreading of cells [GO:0044319]" collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576] extracellular matrix binding [GO:0050840]; growth factor binding [GO:0019838]; heparin binding [GO:0008201]; integrin binding [GO:0005178] 0 3.9376 ELGFDASEVELTR 8.56331 9.63209 8.82314 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.65794 0 0 0 0 0 0 O00623 PEX12_HUMAN Peroxisome assembly protein 12 (Peroxin-12) (Peroxisome assembly factor 3) (PAF-3) PEX12 PAF3 Homo sapiens (Human) "cellular response to reactive oxygen species [GO:0034614]; peroxisome organization [GO:0007031]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein import into peroxisome matrix [GO:0016558]; protein import into peroxisome matrix, receptor recycling [GO:0016562]; protein import into peroxisome matrix, substrate release [GO:0044721]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein targeting to peroxisome [GO:0006625]" cytosol [GO:0005829]; peroxisomal importomer complex [GO:1990429]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777] protein transmembrane transporter activity [GO:0008320]; ubiquitin ligase activator activity [GO:1990757]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.90737 -0.73743 TVCPLCRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.2446 0 0 0 0 0 0 0 9.85806 0 0 0 0 O00634 NET3_HUMAN Netrin-3 (Netrin-2-like protein) NTN3 NTN2L Homo sapiens (Human) axon guidance [GO:0007411]; regulation of transcription by RNA polymerase II [GO:0006357] extracellular region [GO:0005576]; Golgi apparatus [GO:0005794] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; signaling receptor binding [GO:0005102]" 0.89922 -0.64633 EGFYRDPGRALSDR 0 0 0 0 0 0 0 9.46976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O00635 TRI38_HUMAN E3 ubiquitin-protein ligase TRIM38 (EC 2.3.2.27) (RING finger protein 15) (Tripartite motif-containing protein 38) (Zinc finger protein RoRet) TRIM38 RNF15 RORET Homo sapiens (Human) innate immune response [GO:0045087]; negative regulation of defense response to virus [GO:0050687]; positive regulation of autophagy [GO:0010508]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of viral entry into host cell [GO:0046598]; positive regulation of viral genome replication [GO:0045070]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein sumoylation [GO:0016925]; regulation of interferon-beta production [GO:0032648]; regulation of protein localization [GO:0032880]; regulation of viral entry into host cell [GO:0046596] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654] protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; transcription coactivator activity [GO:0003713]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.96594 -2.3577 IRSDFKNLQCFLHEEEK 10.8348 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.0987 0 0 0 0 0 0 0 0 0 O00712 NFIB_HUMAN Nuclear factor 1 B-type (NF1-B) (Nuclear factor 1/B) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/B) (NF-I/B) (NFI-B) (TGGCA-binding protein) NFIB Homo sapiens (Human) anterior commissure morphogenesis [GO:0021960]; brain development [GO:0007420]; cell differentiation involved in salivary gland development [GO:0060689]; cell proliferation in forebrain [GO:0021846]; chondrocyte differentiation [GO:0002062]; club cell differentiation [GO:0060486]; commissural neuron axon guidance [GO:0071679]; DNA replication [GO:0006260]; exit from mitosis [GO:0010458]; glandular epithelial cell differentiation [GO:0002067]; glial cell differentiation [GO:0010001]; glial cell fate specification [GO:0021780]; glial cell proliferation [GO:0014009]; hindbrain development [GO:0030902]; lung ciliated cell differentiation [GO:0061141]; negative regulation of DNA binding [GO:0043392]; negative regulation of epithelial cell proliferation involved in lung morphogenesis [GO:2000795]; negative regulation of mesenchymal cell proliferation involved in lung development [GO:2000791]; negative regulation of miRNA transcription [GO:1902894]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron fate specification [GO:0048665]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; principal sensory nucleus of trigeminal nerve development [GO:0021740]; regeneration [GO:0031099]; regulation of transcription by RNA polymerase II [GO:0006357]; response to bacterium [GO:0009617]; response to wounding [GO:0009611]; retina development in camera-type eye [GO:0060041]; salivary gland cavitation [GO:0060662]; stem cell population maintenance [GO:0019827]; stem cell proliferation [GO:0072089]; tissue homeostasis [GO:0001894]; type I pneumocyte differentiation [GO:0060509]; type II pneumocyte differentiation [GO:0060510] cerebellar mossy fiber [GO:0044300]; chromatin [GO:0000785]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription regulator inhibitor activity [GO:0140416]" 0.85399 0.10536 HPCCVLSNPDQKGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0546 O00716 E2F3_HUMAN Transcription factor E2F3 (E2F-3) E2F3 KIAA0075 Homo sapiens (Human) G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of fat cell proliferation [GO:0070345]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; protein import into nucleus [GO:0006606]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription initiation at RNA polymerase II promoter [GO:0006367] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575] "cis-regulatory region sequence-specific DNA binding [GO:0000987]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein dimerization activity [GO:0046983]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.91375 -0.76146 EVTELSQEEKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.75812 0 0 0 0 0 0 0 0 O00743 PPP6_HUMAN "Serine/threonine-protein phosphatase 6 catalytic subunit (PP6C) (EC 3.1.3.16) [Cleaved into: Serine/threonine-protein phosphatase 6 catalytic subunit, N-terminally processed]" PPP6C PPP6 Homo sapiens (Human) COPII vesicle coating [GO:0048208]; G1/S transition of mitotic cell cycle [GO:0000082]; innate immune response [GO:0045087]; negative regulation of innate immune response [GO:0045824]; protein dephosphorylation [GO:0006470] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] enzyme inhibitor activity [GO:0004857]; metal ion binding [GO:0046872]; myosin phosphatase activity [GO:0017018]; protein serine/threonine phosphatase activity [GO:0004722] 0.95403 -1.5332 YVEIARLCK 0 0 0 9.06797 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O00744 WN10B_HUMAN Protein Wnt-10b (Protein Wnt-12) WNT10B WNT12 Homo sapiens (Human) bone trabecula formation [GO:0060346]; canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; cellular response to cAMP [GO:0071320]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to retinoic acid [GO:0071300]; chondrocyte differentiation [GO:0002062]; epithelial cell differentiation [GO:0030855]; fat cell differentiation [GO:0045444]; fungiform papilla development [GO:0061196]; G2/M transition of mitotic cell cycle [GO:0000086]; hematopoietic stem cell proliferation [GO:0071425]; lipid metabolic process [GO:0006629]; myoblast development [GO:0048627]; myoblast differentiation involved in skeletal muscle regeneration [GO:0014835]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; osteoblast differentiation [GO:0001649]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial cell differentiation [GO:0030858]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of RNA polymerase II transcription preinitiation complex assembly [GO:0045899]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of timing of anagen [GO:0051885]; protein stabilization [GO:0050821]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; regulation of skeletal muscle tissue development [GO:0048641]; sensory perception of taste [GO:0050909]; skeletal muscle fiber development [GO:0048741]; smoothened signaling pathway [GO:0007224]; T cell differentiation [GO:0030217]; transcription by RNA polymerase II [GO:0006366] extracellular region [GO:0005576]; extracellular space [GO:0005615] cytokine activity [GO:0005125]; frizzled binding [GO:0005109]; receptor ligand activity [GO:0048018] 0.89414 -0.51651 CHCRFHWCCYVLCDECK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0238 0 0 0 0 0 O00746 NDKM_HUMAN "Nucleoside diphosphate kinase, mitochondrial (NDK) (NDP kinase, mitochondrial) (EC 2.7.4.6) (Nucleoside diphosphate kinase D) (NDPKD) (nm23-H4)" NME4 NM23D Homo sapiens (Human) CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; lipid transport [GO:0006869]; nucleoside metabolic process [GO:0009116]; phosphorylation [GO:0016310]; UTP biosynthetic process [GO:0006228] mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; cardiolipin binding [GO:1901612]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550] 0.81617 0.22087 LVGDVIQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2312 0 0 0 0 0 0 0 0 0 0 0 O00750 P3C2B_HUMAN Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (PI3K-C2-beta) (PtdIns-3-kinase C2 subunit beta) (EC 2.7.1.137) (EC 2.7.1.154) (C2-PI3K) (Phosphoinositide 3-kinase-C2-beta) PIK3C2B Homo sapiens (Human) autophagosome organization [GO:1905037]; cell migration [GO:0016477]; cellular response to starvation [GO:0009267]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; protein kinase B signaling [GO:0043491] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; phosphatidylinositol 3-kinase complex [GO:0005942]; plasma membrane [GO:0005886] 1-phosphatidylinositol-3-kinase activity [GO:0016303]; 1-phosphatidylinositol-4-phosphate 3-kinase activity [GO:0035005]; ATP binding [GO:0005524]; phosphatidylinositol binding [GO:0035091] 0.96893 -6.5503 DIMQKESLYWLTDADK 0 0 15.6527 0 0 9.8997 0 0 0 0 0 10.0868 0 0 0 0 0 0 0 0 0 8.3881 10.4716 0 0 0 0 O00754 MA2B1_HUMAN Lysosomal alpha-mannosidase (Laman) (EC 3.2.1.24) (Lysosomal acid alpha-mannosidase) (Mannosidase alpha class 2B member 1) (Mannosidase alpha-B) [Cleaved into: Lysosomal alpha-mannosidase A peptide; Lysosomal alpha-mannosidase B peptide; Lysosomal alpha-mannosidase C peptide; Lysosomal alpha-mannosidase D peptide; Lysosomal alpha-mannosidase E peptide] MAN2B1 LAMAN MANB Homo sapiens (Human) learning or memory [GO:0007611]; mannose metabolic process [GO:0006013]; oligosaccharide catabolic process [GO:0009313]; protein deglycosylation [GO:0006517]; protein modification process [GO:0036211] azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654] alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872] 0.88482 -0.21437 LDYQDKWVRMQK 0 0 0 0 0 0 0 0 0 0 9.2021 0 0 0 0 0 0 0 0 0 0 8.87267 0 0 0 10.7805 10.2188 O00755 WNT7A_HUMAN Protein Wnt-7a WNT7A Homo sapiens (Human) "angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; asymmetric protein localization involved in cell fate determination [GO:0045167]; axonogenesis [GO:0007409]; canonical Wnt signaling pathway [GO:0060070]; cartilage condensation [GO:0001502]; cell fate commitment [GO:0045165]; cell proliferation in forebrain [GO:0021846]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system vasculogenesis [GO:0022009]; cerebellar granule cell differentiation [GO:0021707]; chondrocyte differentiation [GO:0002062]; dendritic spine morphogenesis [GO:0060997]; dorsal/ventral pattern formation [GO:0009953]; embryonic axis specification [GO:0000578]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; establishment of blood-brain barrier [GO:0060856]; establishment of cell polarity [GO:0030010]; excitatory synapse assembly [GO:1904861]; lens fiber cell development [GO:0070307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of neurogenesis [GO:0050768]; neuron differentiation [GO:0030182]; neurotransmitter secretion [GO:0007269]; oviduct development [GO:0060066]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of excitatory synapse assembly [GO:1904891]; positive regulation of gene expression [GO:0010628]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein localization to presynapse [GO:1905386]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of synapse assembly [GO:0051965]; positive regulation of transcription by RNA polymerase II [GO:0045944]; postsynapse assembly [GO:0099068]; presynapse assembly [GO:0099054]; regulation of axon diameter [GO:0031133]; regulation of postsynapse organization [GO:0099175]; regulation of presynapse assembly [GO:1905606]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; secondary palate development [GO:0062009]; sex differentiation [GO:0007548]; skeletal muscle satellite cell activation [GO:0014719]; skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration [GO:0014834]; somatic stem cell division [GO:0048103]; somatic stem cell population maintenance [GO:0035019]; stem cell development [GO:0048864]; synaptic vesicle recycling [GO:0036465]; uterus morphogenesis [GO:0061038]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of epidermal cells [GO:0035313]" cell surface [GO:0009986]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; Schaffer collateral - CA1 synapse [GO:0098685] cytokine activity [GO:0005125]; frizzled binding [GO:0005109]; receptor ligand activity [GO:0048018]; signaling receptor binding [GO:0005102] 0.96846 -3.3504 DEGWKWGGCSADIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.65094 0 0 0 0 0 0 O00757 F16P2_HUMAN "Fructose-1,6-bisphosphatase isozyme 2 (FBPase 2) (EC 3.1.3.11) (D-fructose-1,6-bisphosphate 1-phosphohydrolase 2) (Muscle FBPase)" FBP2 Homo sapiens (Human) "fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose 6-phosphate metabolic process [GO:0006002]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; sucrose biosynthetic process [GO:0005986]" anchoring junction [GO:0070161]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; Z disc [GO:0030018] "fructose 1,6-bisphosphate 1-phosphatase activity [GO:0042132]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]" 0.9541 -1.5224 GKIYSLNEGYAK 0 0 0 0 0 0 0 0 0 0 0 9.99025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O00763 ACACB_HUMAN Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) ACACB ACC2 ACCB Homo sapiens (Human) acetyl-CoA metabolic process [GO:0006084]; energy homeostasis [GO:0097009]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of catalytic activity [GO:0043086]; negative regulation of fatty acid beta-oxidation [GO:0031999]; negative regulation of gene expression [GO:0010629]; positive regulation of heart growth [GO:0060421]; positive regulation of lipid storage [GO:0010884]; protein homotetramerization [GO:0051289]; regulation of glucose metabolic process [GO:0010906]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to xenobiotic stimulus [GO:0009410] cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleus [GO:0005634] acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin binding [GO:0009374]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872] 0.9303 -1.2382 EKLPLMIFANWR 0 0 0 0 0 10.9205 0 0 0 12.748 0 0 0 0 0 0 0 12.2882 0 0 0 0 0 8.27076 0 0 0 O00764 PDXK_HUMAN Pyridoxal kinase (EC 2.7.1.35) (Pyridoxine kinase) PDXK C21orf124 C21orf97 PKH PNK PRED79 Homo sapiens (Human) phosphorylation [GO:0016310]; pyridoxal 5'-phosphate salvage [GO:0009443] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580] ATP binding [GO:0005524]; lithium ion binding [GO:0031403]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; protein homodimerization activity [GO:0042803]; pyridoxal kinase activity [GO:0008478]; pyridoxal phosphate binding [GO:0030170]; sodium ion binding [GO:0031402]; zinc ion binding [GO:0008270] 0.41804 0.679 DIEDPEIVVQATVL 0 0 0 0 0 0 0 0 0 0 0 0 9.69954 9.4103 0 0 0 0 0 0 0 0 0 0 9.37658 0 0 O00767 SCD_HUMAN Stearoyl-CoA desaturase (hSCD1) (EC 1.14.19.1) (Acyl-CoA desaturase) (Delta(9)-desaturase) (Delta-9 desaturase) (Fatty acid desaturase) SCD FADS5 SCD1 SCDOS Homo sapiens (Human) positive regulation of cold-induced thermogenesis [GO:0120162]; response to fatty acid [GO:0070542]; unsaturated fatty acid biosynthetic process [GO:0006636] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; nucleolus [GO:0005730] iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; palmitoyl-CoA 9-desaturase activity [GO:0032896]; stearoyl-CoA 9-desaturase activity [GO:0004768] 0.95481 -1.5703 LWSHRSYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.69335 0 0 0 0 O14490 DLGP1_HUMAN Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (hGKAP) (PSD-95/SAP90-binding protein 1) (SAP90/PSD-95-associated protein 1) (SAPAP1) DLGAP1 DAP1 GKAP Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic specialization [GO:0099572] molecular adaptor activity [GO:0060090]; protein-containing complex binding [GO:0044877] 0.88176 -0.026865 IRHLVHSVQK 0 0 13.7757 0 0 9.11473 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O14492 SH2B2_HUMAN SH2B adapter protein 2 (Adapter protein with pleckstrin homology and Src homology 2 domains) (SH2 and PH domain-containing adapter protein APS) SH2B2 APS Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; antigen receptor-mediated signaling pathway [GO:0050851]; B cell receptor signaling pathway [GO:0050853]; B-1 B cell homeostasis [GO:0001922]; brown fat cell differentiation [GO:0050873]; cytokine-mediated signaling pathway [GO:0019221]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; nervous system development [GO:0007399]; regulation of metabolic process [GO:0019222]; regulation of Ras protein signal transduction [GO:0046578] actin filament [GO:0005884]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stress fiber [GO:0001725] identical protein binding [GO:0042802]; SH2 domain binding [GO:0042169]; signaling adaptor activity [GO:0035591]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068] 0.91075 -0.74696 FRLEFFVPPK 0 0 0 0 10.0829 0 0 0 0 0 15.3086 0 12.73 0 0 0 13.2292 13.2781 0 0 0 0 0 0 0 0 9.09167 O14495 PLPP3_HUMAN Phospholipid phosphatase 3 (EC 3.1.3.-) (EC 3.1.3.4) (Lipid phosphate phosphohydrolase 3) (PAP2-beta) (Phosphatidate phosphohydrolase type 2b) (Phosphatidic acid phosphatase 2b) (PAP-2b) (PAP2b) (Vascular endothelial growth factor and type I collagen-inducible protein) (VCIP) PLPP3 LPP3 PPAP2B Homo sapiens (Human) "Bergmann glial cell differentiation [GO:0060020]; blood vessel development [GO:0001568]; cell-cell adhesion mediated by integrin [GO:0033631]; ceramide metabolic process [GO:0006672]; gastrulation with mouth forming second [GO:0001702]; homotypic cell-cell adhesion [GO:0034109]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of protein phosphorylation [GO:0001933]; phospholipid dephosphorylation [GO:0046839]; phospholipid metabolic process [GO:0006644]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; protein stabilization [GO:0050821]; regulation of sphingolipid mediated signaling pathway [GO:1902068]; regulation of Wnt signaling pathway [GO:0030111]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; signal transduction [GO:0007165]; sphingolipid biosynthetic process [GO:0030148]; sphingosine metabolic process [GO:0006670]; wound healing [GO:0042060]" adherens junction [GO:0005912]; basolateral plasma membrane [GO:0016323]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802] ceramide-1-phosphate phosphatase activity [GO:0106235]; integrin binding [GO:0005178]; phosphatidate phosphatase activity [GO:0008195]; sphingosine-1-phosphate phosphatase activity [GO:0042392] 0.87251 0.050587 NGGSPALNNNPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.02137 0 0 0 0 O14497 ARI1A_HUMAN "AT-rich interactive domain-containing protein 1A (ARID domain-containing protein 1A) (B120) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A) (Osa homolog 1) (hOSA1) (SWI-like protein) (SWI/SNF complex protein p270) (SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1) (hELD)" ARID1A BAF250 BAF250A C1orf4 OSA1 SMARCF1 Homo sapiens (Human) androgen receptor signaling pathway [GO:0030521]; chromatin remodeling [GO:0006338]; glucocorticoid receptor signaling pathway [GO:0042921]; intracellular estrogen receptor signaling pathway [GO:0030520]; nervous system development [GO:0007399]; nucleosome disassembly [GO:0006337]; positive regulation of cell differentiation [GO:0045597]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of T cell differentiation [GO:0045582]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription initiation-coupled chromatin remodeling [GO:0045815] bBAF complex [GO:0140092]; brahma complex [GO:0035060]; chromatin [GO:0000785]; nBAF complex [GO:0071565]; npBAF complex [GO:0071564]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SWI/SNF complex [GO:0016514] DNA binding [GO:0003677]; nuclear receptor binding [GO:0016922]; transcription coactivator activity [GO:0003713] 0.96578 -2.2961 AAGPGLGNVAMGPR 10.5404 0 11.2488 0 0 0 9.4522 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.40852 0 9.5887 O14511 NRG2_HUMAN "Pro-neuregulin-2, membrane-bound isoform (Pro-NRG2) [Cleaved into: Neuregulin-2 (NRG-2) (Divergent of neuregulin-1) (DON-1) (Neural- and thymus-derived activator for ERBB kinases) (NTAK)]" NRG2 NTAK Homo sapiens (Human) animal organ development [GO:0048513]; intracellular signal transduction [GO:0035556]; nervous system development [GO:0007399]; signal transduction [GO:0007165] extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] growth factor activity [GO:0008083]; signaling receptor binding [GO:0005102] 0.96767 -2.9289 LYMPDPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.61121 0 10.8533 0 0 0 O14513 NCKP5_HUMAN Nck-associated protein 5 (NAP-5) (Peripheral clock protein) NCKAP5 ERIH NAP5 Homo sapiens (Human) microtubule bundle formation [GO:0001578]; microtubule depolymerization [GO:0007019] microtubule plus-end [GO:0035371] 0.96858 -3.3234 DYTFFKRSEEDTEK 12.266 12.1678 0 0 9.47515 9.54628 11.5053 0 0 0 0 13.8258 9.9976 0 0 10.2002 14.199 0 0 11.3257 0 0 0 0 10.9037 0 0 O14514 AGRB1_HUMAN Adhesion G protein-coupled receptor B1 (Brain-specific angiogenesis inhibitor 1) [Cleaved into: Vasculostatin-40 (Vstat40); Vasculostatin-120 (Vstat120)] ADGRB1 BAI1 Homo sapiens (Human) "adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; apoptotic cell clearance [GO:0043277]; axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; defense response to Gram-negative bacterium [GO:0050829]; engulfment of apoptotic cell [GO:0043652]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; muscle organ development [GO:0007517]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein ubiquitination [GO:0031397]; peripheral nervous system development [GO:0007422]; phagocytosis, recognition [GO:0006910]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of synapse assembly [GO:0051965]; regulation of synaptic plasticity [GO:0048167]; signal transduction [GO:0007165]" cell-cell junction [GO:0005911]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] G protein-coupled receptor activity [GO:0004930]; lipopolysaccharide binding [GO:0001530]; PDZ domain binding [GO:0030165]; phosphatidylserine binding [GO:0001786] 0.92185 -1.0894 DIAACRTATITGTLK 0 0 0 0 0 9.89241 0 0 0 9.34921 0 0 0 0 0 0 0 0 0 11.4812 0 0 0 0 0 0 10.3087 O14521 DHSD_HUMAN "Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial (CybS) (CII-4) (QPs3) (Succinate dehydrogenase complex subunit D) (Succinate-ubiquinone oxidoreductase cytochrome b small subunit) (Succinate-ubiquinone reductase membrane anchor subunit)" SDHD SDH4 Homo sapiens (Human) "cellular response to hypoxia [GO:0071456]; mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]; regulation of catecholamine secretion [GO:0050433]; tricarboxylic acid cycle [GO:0006099]" "mitochondrial envelope [GO:0005740]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; mitochondrion [GO:0005739]" electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039] 0.91542 -0.81225 AVAMLWKL 0 0 0 0 0 9.40357 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O14523 C2C2L_HUMAN Phospholipid transfer protein C2CD2L (C2 domain-containing protein 2-like) (C2CD2-like) (Transmembrane protein 24) C2CD2L KIAA0285 TMEM24 DLNB23 Homo sapiens (Human) positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774] cortical endoplasmic reticulum [GO:0032541]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-plasma membrane contact site [GO:0140268]; plasma membrane [GO:0005886] insulin binding [GO:0043559]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol transfer activity [GO:0008526] 0.8876 -0.35096 FSFKSKPKANGNPSPQL 10.0753 10.2274 10.3889 0 0 10.558 10.0699 9.73076 0 13.0615 11.8849 11.9948 0 0 0 0 0 0 10.1933 0 0 0 0 10.1167 0 0 0 O14524 NEMP1_HUMAN Nuclear envelope integral membrane protein 1 NEMP1 KIAA0286 TMEM194 TMEM194A Homo sapiens (Human) nuclear membrane organization [GO:0071763] nuclear envelope [GO:0005635]; nuclear inner membrane [GO:0005637] 0.84918 0.16289 NLEHPIQWLYITCR 0 0 0 0 0 0 0 0 0 9.61464 0 0 0 0 0 0 0 0 0 0 0 10.4293 0 0 0 9.08648 0 O14525 ASTN1_HUMAN Astrotactin-1 ASTN1 ASTN KIAA0289 Homo sapiens (Human) locomotory behavior [GO:0007626]; neuron cell-cell adhesion [GO:0007158]; neuron migration [GO:0001764] clathrin-coated vesicle [GO:0030136]; endosome [GO:0005768]; external side of plasma membrane [GO:0009897]; perikaryon [GO:0043204] 0.96811 -3.6593 ELECKLK 9.41519 15.9554 0 0 0 0 0 0 0 0 0 0 0 0 9.55827 0 0 12.7093 0 8.57183 0 0 0 0 0 0 0 O14526 FCHO1_HUMAN F-BAR domain only protein 1 FCHO1 KIAA0290 Homo sapiens (Human) clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; positive regulation of T cell activation [GO:0050870]; T cell receptor signaling pathway [GO:0050852] clathrin-coated pit [GO:0005905]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] AP-2 adaptor complex binding [GO:0035612] 0.86318 0.08957 SYFGEHFWGEK 0 0 0 0 0 0 0 0 0 0 0 9.61043 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O14529 CUX2_HUMAN Homeobox protein cut-like 2 (Homeobox protein cux-2) CUX2 CUTL2 KIAA0293 Homo sapiens (Human) cellular response to organic substance [GO:0071310]; cognition [GO:0050890]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of synapse assembly [GO:0051965]; short-term memory [GO:0007614] chromatin [GO:0000785]; extracellular exosome [GO:0070062]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.88987 -0.49845 DLHTSWKR 0 0 8.8415 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.73515 10.4662 0 0 0 O14530 TXND9_HUMAN Thioredoxin domain-containing protein 9 (ATP-binding protein associated with cell differentiation) (Protein 1-4) TXNDC9 APACD Homo sapiens (Human) microtubule cytoskeleton organization [GO:0000226] centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; nucleus [GO:0005634] cadherin binding [GO:0045296] 0.96345 -2.1162 DSTFRCK 0 0 0 0 0 0 0 0 0 9.87124 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O14531 DPYL4_HUMAN Dihydropyrimidinase-related protein 4 (DRP-4) (Collapsin response mediator protein 3) (CRMP-3) (UNC33-like phosphoprotein 4) (ULIP-4) DPYSL4 CRMP3 ULIP4 Homo sapiens (Human) nervous system development [GO:0007399] cytosol [GO:0005829] "filamin binding [GO:0031005]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [GO:0016812]" 0.96397 -2.2535 SIPRITSDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.8031 0 0 0 0 O14545 TRAD1_HUMAN TRAF-type zinc finger domain-containing protein 1 (Protein FLN29) TRAFD1 FLN29 Homo sapiens (Human) negative regulation of innate immune response [GO:0045824] mitochondrion [GO:0005739] metal ion binding [GO:0046872] 0.88928 -0.42985 HEETECPLRLAVCQHCDLELSILKLK 10.0151 0 8.37977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0507 0 0 O14556 G3PT_HUMAN "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific (EC 1.2.1.12) (Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2) (GAPDH-2) (Spermatogenic glyceraldehyde-3-phosphate dehydrogenase)" GAPDHS GAPD2 GAPDH2 GAPDS HSD-35 HSD35 Homo sapiens (Human) flagellated sperm motility [GO:0030317]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; positive regulation of glycolytic process [GO:0045821] cytosol [GO:0005829]; nucleus [GO:0005634] glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661] 0.89858 -0.61973 LTGMAFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.8089 0 0 0 0 0 O14559 RHG33_HUMAN Rho GTPase-activating protein 33 (Rho-type GTPase-activating protein 33) (Sorting nexin-26) (Tc10/CDC42 GTPase-activating protein) ARHGAP33 SNX26 TCGAP Homo sapiens (Human) protein transport [GO:0015031]; regulation of dendritic spine morphogenesis [GO:0061001]; response to toxic substance [GO:0009636]; small GTPase mediated signal transduction [GO:0007264] actin cytoskeleton [GO:0015629]; cell cortex [GO:0005938]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; fibrillar center [GO:0001650]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] GTPase activator activity [GO:0005096]; phosphatidylinositol binding [GO:0035091]; protein kinase binding [GO:0019901] 0.8964 -0.54463 LMALALAER 0 10.1351 0 0 0 0 0 0 0 0 0 9.2292 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O14561 ACPM_HUMAN "Acyl carrier protein, mitochondrial (ACP) (CI-SDAP) (NADH-ubiquinone oxidoreductase 9.6 kDa subunit)" NDUFAB1 Homo sapiens (Human) "[2Fe-2S] cluster assembly [GO:0044571]; aerobic respiration [GO:0009060]; fatty acid biosynthetic process [GO:0006633]; iron-sulfur cluster assembly [GO:0016226]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; protein lipoylation [GO:0009249]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]" iron-sulfur cluster assembly complex [GO:1990229]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex I [GO:0005747]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; calcium ion binding [GO:0005509]; fatty acid binding [GO:0005504]; mitochondrial large ribosomal subunit binding [GO:0140978] 0.81348 0.22282 LSVNSHFMK 0 0 0 0 0 0 0 0 0 0 9.76505 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O14576 DC1I1_HUMAN "Cytoplasmic dynein 1 intermediate chain 1 (Cytoplasmic dynein intermediate chain 1) (Dynein intermediate chain 1, cytosolic) (DH IC-1)" DYNC1I1 DNCI1 DNCIC1 Homo sapiens (Human) transport along microtubule [GO:0010970]; vesicle transport along microtubule [GO:0047496] cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; kinetochore [GO:0000776]; microtubule [GO:0005874]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; spindle pole [GO:0000922]; vesicle [GO:0031982] cytoskeletal motor activity [GO:0003774]; dynein heavy chain binding [GO:0045504]; dynein light chain binding [GO:0045503]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777]; spectrin binding [GO:0030507] 0.96187 -2.5603 EVVSYSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.14822 8.76208 0 0 0 0 9.66642 0 0 O14578 CTRO_HUMAN Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21) CIT CRIK KIAA0949 STK21 Homo sapiens (Human) G2/M transition of mitotic cell cycle [GO:0000086]; generation of neurons [GO:0048699]; Golgi organization [GO:0007030]; liver development [GO:0001889]; mitotic cell cycle [GO:0000278]; mitotic cytokinesis [GO:0000281]; negative regulation of hippo signaling [GO:0035331]; neuron apoptotic process [GO:0051402]; positive regulation of cytokinesis [GO:0032467]; protein phosphorylation [GO:0006468]; regulation of actin polymerization or depolymerization [GO:0008064] cleavage furrow [GO:0032154]; cytosol [GO:0005829]; Golgi cisterna [GO:0031985]; membrane [GO:0016020]; midbody [GO:0030496]; neuronal cell body [GO:0043025]; nucleus [GO:0005634] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine kinase inhibitor activity [GO:0030291]; scaffold protein binding [GO:0097110]; SH3 domain binding [GO:0017124]; transcription coactivator binding [GO:0001223] 0.96887 -10.862 ADVPYILKMESHPHTTCWPGR 10.2009 0 0 0 0 0 0 0 0 0 10.2144 12.074 0 0 0 0 10.4885 11.6779 0 8.52888 0 0 0 8.96443 0 0 0 O14579 COPE_HUMAN Coatomer subunit epsilon (Epsilon-coat protein) (Epsilon-COP) COPE Homo sapiens (Human) "endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein localization to axon [GO:0099612]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]" COPI vesicle coat [GO:0030126]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; transport vesicle [GO:0030133] structural molecule activity [GO:0005198] 0.55795 0.55209 DSIVAELDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6989 0 O14594 NCAN_HUMAN Neurocan core protein (Chondroitin sulfate proteoglycan 3) NCAN CSPG3 NEUR Homo sapiens (Human) cell adhesion [GO:0007155]; glial cell differentiation [GO:0010001]; positive regulation of neuroblast proliferation [GO:0002052] extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; lysosomal lumen [GO:0043202]; perineuronal net [GO:0072534]; synapse [GO:0045202] calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; hyaluronic acid binding [GO:0005540] 0.86156 0.094579 HPTEDWEKDEGNFC 10.4575 0 10.3648 0 0 9.47553 10.3213 10.3397 0 11.1539 0 11.1653 9.08794 9.3386 9.48037 9.13386 8.74204 0 0 0 0 0 0 0 0 0 0 O14595 CTDS2_HUMAN Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 (EC 3.1.3.16) (Nuclear LIM interactor-interacting factor 2) (NLI-interacting factor 2) (Protein OS-4) (Small C-terminal domain phosphatase 2) (Small CTD phosphatase 2) (SCP2) CTDSP2 NIF2 OS4 SCP2 Homo sapiens (Human) negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of protein phosphorylation [GO:0001933]; protein dephosphorylation [GO:0006470] nucleoplasm [GO:0005654] metal ion binding [GO:0046872]; myosin phosphatase activity [GO:0017018]; RNA polymerase II CTD heptapeptide repeat phosphatase activity [GO:0008420] 0.81158 0.22212 ESCVFHQGCYVK 0 0 0 0 0 0 0 0 0 9.84984 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O14598 VCY1_HUMAN "Testis-specific basic protein Y 1 (Basic charge, Y-linked 1) (Variably charged protein Y)" VCY BPY1 VCY1A; VCY1B BPY1B Homo sapiens (Human) brain development [GO:0007420] 0.79852 0.23965 SSSQPSPSGPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.61802 0 0 0 0 0 0 0 0 0 O14604 TYB4Y_HUMAN "Thymosin beta-4, Y-chromosomal" TMSB4Y TB4Y Homo sapiens (Human) actin filament organization [GO:0007015]; regulation of actin polymerization or depolymerization [GO:0008064]; regulation of cell migration [GO:0030334]; sequestering of actin monomers [GO:0042989] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; nucleus [GO:0005634] actin monomer binding [GO:0003785] 0.89715 -0.52865 LKKTETQEK 10.5705 10.5351 10.4942 0 0 0 10.7336 10.7465 10.7762 0 0 11.1107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O14607 UTY_HUMAN Histone demethylase UTY (EC 1.14.11.68) (Ubiquitously-transcribed TPR protein on the Y chromosome) (Ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein) ([histone H3]-trimethyl-L-lysine(27) demethylase UTY) UTY KDM6C Homo sapiens (Human) histone H3-K27 demethylation [GO:0071557]; regulation of gene expression [GO:0010468] MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654] chromatin DNA binding [GO:0031490]; histone demethylase activity [GO:0032452]; histone H3K27me2/H3K27me3 demethylase activity [GO:0071558]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.95528 -1.5373 LNPPTPSIYLENKR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.22908 0 0 0 0 0 0 0 0 0 0 0 0 0 O14610 GBGT2_HUMAN Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 (G gamma-C) (G-gamma-8) (G-gamma-9) (Guanine nucleotide binding protein gamma transducing activity polypeptide 2) GNGT2 GNG8 GNG9 GNGT8 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; phototransduction [GO:0007602] heterotrimeric G-protein complex [GO:0005834] G-protein beta-subunit binding [GO:0031681]; GTPase activity [GO:0003924] 0.93239 -1.2769 MAQDLSEKDLLK 0 0 0 0 10.428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O14618 CCS_HUMAN Copper chaperone for superoxide dismutase (Superoxide dismutase copper chaperone) CCS Homo sapiens (Human) cellular response to oxidative stress [GO:0034599]; positive regulation of oxidoreductase activity [GO:0051353]; protein maturation by copper ion transfer [GO:0015680]; removal of superoxide radicals [GO:0019430]; superoxide metabolic process [GO:0006801] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; protein-disulfide reductase activity [GO:0015035]; superoxide dismutase copper chaperone activity [GO:0016532] 0.80263 0.23984 FLQLTPER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0146 0 0 O14625 CXL11_HUMAN C-X-C motif chemokine 11 (Beta-R1) (H174) (Interferon gamma-inducible protein 9) (IP-9) (Interferon-inducible T-cell alpha chemoattractant) (I-TAC) (Small-inducible cytokine B11) CXCL11 ITAC SCYB11 SCYB9B Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell-cell signaling [GO:0007267]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; inflammatory response [GO:0006954]; killing of cells of another organism [GO:0031640]; neutrophil chemotaxis [GO:0030593]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; regulation of cell population proliferation [GO:0042127]; signal transduction [GO:0007165]; T cell chemotaxis [GO:0010818] extracellular region [GO:0005576]; extracellular space [GO:0005615] chemokine activity [GO:0008009]; CXCR chemokine receptor binding [GO:0045236]; CXCR3 chemokine receptor binding [GO:0048248]; heparin binding [GO:0008201] 0.71403 0.36627 ENKGQRCLNPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.57363 0 0 0 0 O14626 GP171_HUMAN G-protein coupled receptor 171 (G-protein coupled receptor H963) GPR171 H963 Homo sapiens (Human) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of myeloid cell differentiation [GO:0045638]; regulation of feeding behavior [GO:0060259]; regulation of sensory perception of pain [GO:0051930] membrane [GO:0016020]; plasma membrane [GO:0005886] G protein-coupled peptide receptor activity [GO:0008528]; G protein-coupled purinergic nucleotide receptor activity [GO:0045028]; G protein-coupled receptor activity [GO:0004930]; neuropeptide binding [GO:0042923]; neuropeptide receptor activity [GO:0008188] 0.8012 0.23938 TNSSFFCPVYK 0 0 0 0 0 0 0 9.92881 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O14627 CDX4_HUMAN Homeobox protein CDX-4 (Caudal-type homeobox protein 4) CDX4 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; anterior/posterior axis specification [GO:0009948]; blood vessel development [GO:0001568]; cell differentiation [GO:0030154]; labyrinthine layer development [GO:0060711]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.87839 0.0037487 MYGSCLLEK 9.41018 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O14628 ZN195_HUMAN Zinc finger protein 195 ZNF195 ZNFP104 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; zinc ion binding [GO:0008270]" 0.90238 -0.6979 GYGNCGLDNLYLR 0 11.2042 0 0 0 0 0 0 0 0 0 10.4193 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O14638 ENPP3_HUMAN Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (E-NPP 3) (NPP3) (Phosphodiesterase I beta) (PD-Ibeta) (Phosphodiesterase I/nucleotide pyrophosphatase 3) (CD antigen CD203c) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (NPPase) (EC 3.6.1.9) (Nucleotide diphosphatase)] ENPP3 PDNP3 Homo sapiens (Human) ATP metabolic process [GO:0046034]; basophil activation involved in immune response [GO:0002276]; negative regulation of inflammatory response [GO:0050728]; negative regulation of mast cell activation involved in immune response [GO:0033007]; negative regulation of mast cell proliferation [GO:0070667]; nucleoside triphosphate catabolic process [GO:0009143]; phosphate ion homeostasis [GO:0055062]; phosphate-containing compound metabolic process [GO:0006796]; pyrimidine nucleotide metabolic process [GO:0006220] apical plasma membrane [GO:0016324]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471] calcium ion binding [GO:0005509]; nucleic acid binding [GO:0003676]; nucleoside triphosphate diphosphatase activity [GO:0047429]; phosphodiesterase I activity [GO:0004528]; zinc ion binding [GO:0008270] 0.96915 -3.3132 GLENCRCDVACK 0 0 0 0 8.85941 0 0 0 0 0 0 0 0 0 0 8.99294 0 0 0 0 0 0 0 0 0 0 0 O14639 ABLM1_HUMAN Actin-binding LIM protein 1 (abLIM-1) (Actin-binding LIM protein family member 1) (Actin-binding double zinc finger protein) (LIMAB1) (Limatin) ABLIM1 ABLIM KIAA0059 LIMAB1 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cilium assembly [GO:0060271]; cytoskeleton organization [GO:0007010]; lamellipodium assembly [GO:0030032]; visual perception [GO:0007601] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; lamellipodium [GO:0030027]; stress fiber [GO:0001725] actin binding [GO:0003779]; actin filament binding [GO:0051015]; metal ion binding [GO:0046872] 0.91689 -0.84495 QWHLGCFKCKSCGK 0 0 0 10.2492 0 0 0 0 0 0 0 0 0 0 0 0 0 9.83211 0 0 0 0 0 0 0 0 0 O14646 CHD1_HUMAN Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1) CHD1 Homo sapiens (Human) chromatin remodeling [GO:0006338]; nucleosome organization [GO:0034728]; positive regulation by host of viral transcription [GO:0043923]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent chromatin remodeler activity [GO:0140658]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; helicase activity [GO:0004386]; histone binding [GO:0042393]; methylated histone binding [GO:0035064] 0.96884 -8.4538 ASSSGPR 0 8.2502 7.71101 7.90346 0 0 0 0 10.2904 0 9.51968 0 0 0 0 0 9.65191 0 0 9.92967 9.76759 0 0 9.37374 0 0 0 O14647 CHD2_HUMAN Chromodomain-helicase-DNA-binding protein 2 (CHD-2) (EC 3.6.4.12) (ATP-dependent helicase CHD2) CHD2 Homo sapiens (Human) DNA damage response [GO:0006974]; gene expression [GO:0010467]; hematopoietic stem cell differentiation [GO:0060218]; muscle organ development [GO:0007517]; nucleosome organization [GO:0034728]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent chromatin remodeler activity [GO:0140658]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; helicase activity [GO:0004386]; histone binding [GO:0042393]; RNA binding [GO:0003723]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96964 -3.5033 ENKEKQMSSR 0 0 0 0 10.0097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.56541 0 0 0 0 0 0 O14653 GOSR2_HUMAN Golgi SNAP receptor complex member 2 (27 kDa Golgi SNARE protein) (Membrin) GOSR2 GS27 Homo sapiens (Human) intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]; vesicle fusion [GO:0006906] cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; late endosome membrane [GO:0031902]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; SNARE complex [GO:0031201] SNAP receptor activity [GO:0005484]; SNARE binding [GO:0000149] 0.87102 0.039379 QVHEIQSCMGRLETADK 9.7932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O14654 IRS4_HUMAN Insulin receptor substrate 4 (IRS-4) (160 kDa phosphotyrosine protein) (py160) (Phosphoprotein of 160 kDa) (pp160) IRS4 Homo sapiens (Human) insulin receptor signaling pathway [GO:0008286]; signal transduction [GO:0007165] cytosol [GO:0005829]; plasma membrane [GO:0005886] insulin receptor binding [GO:0005158]; phosphatidylinositol 3-kinase binding [GO:0043548] 0.96691 -2.3209 CSEPPPVAR 12.4726 0 0 0 0 0 0 0 0 0 0 10.7144 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7629 9.55303 O14656 TOR1A_HUMAN Torsin-1A (Dystonia 1 protein) (Torsin ATPase-1A) (EC 3.6.4.-) (Torsin family 1 member A) TOR1A DQ2 DYT1 TA TORA Homo sapiens (Human) "cell adhesion [GO:0007155]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein folding [GO:0061077]; ER-associated misfolded protein catabolic process [GO:0071712]; intermediate filament cytoskeleton organization [GO:0045104]; neuron projection development [GO:0031175]; nuclear envelope organization [GO:0006998]; nuclear membrane organization [GO:0071763]; organelle organization [GO:0006996]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; protein deneddylation [GO:0000338]; protein localization to nucleus [GO:0034504]; regulation of dopamine uptake involved in synaptic transmission [GO:0051584]; regulation of protein localization to cell surface [GO:2000008]; response to oxidative stress [GO:0006979]; synaptic vesicle membrane organization [GO:0048499]; synaptic vesicle transport [GO:0048489]; wound healing, spreading of cells [GO:0044319]" cytoplasmic vesicle membrane [GO:0030659]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extrinsic component of endoplasmic reticulum membrane [GO:0042406]; growth cone [GO:0030426]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; kinesin binding [GO:0019894]; misfolded protein binding [GO:0051787]; unfolded protein binding [GO:0051082] 0.86419 0.082066 ITDVALDFWR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.90857 0 0 O14657 TOR1B_HUMAN Torsin-1B (Torsin ATPase-1B) (EC 3.6.4.-) (Torsin family 1 member B) TOR1B DQ1 FKSG18 Homo sapiens (Human) chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum organization [GO:0007029]; nuclear membrane organization [GO:0071763]; protein localization to nucleus [GO:0034504]; response to unfolded protein [GO:0006986] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; identical protein binding [GO:0042802]; kinesin binding [GO:0019894] 0.96324 -2.6613 IYSDKGCKTVQSR 0 8.75576 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.92092 0 0 0 0 0 0 O14662 STX16_HUMAN Syntaxin-16 (Syn16) STX16 Homo sapiens (Human) "endocytic recycling [GO:0032456]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; SNARE complex [GO:0031201]; synaptic vesicle membrane [GO:0030672]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588] SNAP receptor activity [GO:0005484]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905] 0.96004 -1.8983 ATRRLTDAFLLLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1192 0 0 0 9.83281 0 0 10.1289 0 0 0 O14672 ADA10_HUMAN Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (CDw156) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c) ADAM10 KUZ MADM Homo sapiens (Human) adherens junction organization [GO:0034332]; amyloid precursor protein catabolic process [GO:0042987]; cell-cell signaling [GO:0007267]; cochlea development [GO:0090102]; constitutive protein ectodomain proteolysis [GO:0051089]; epidermal growth factor receptor ligand maturation [GO:0038004]; extracellular matrix disassembly [GO:0022617]; in utero embryonic development [GO:0001701]; integrin-mediated signaling pathway [GO:0007229]; membrane protein ectodomain proteolysis [GO:0006509]; monocyte activation [GO:0042117]; negative regulation of cell adhesion [GO:0007162]; negative regulation of gene expression [GO:0010629]; Notch signaling pathway [GO:0007219]; pore complex assembly [GO:0046931]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of T cell chemotaxis [GO:0010820]; postsynapse organization [GO:0099173]; protein catabolic process at postsynapse [GO:0140249]; protein phosphorylation [GO:0006468]; protein processing [GO:0016485]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of Notch signaling pathway [GO:0008593]; regulation of postsynapse organization [GO:0099175]; regulation of vasculature development [GO:1901342]; response to tumor necrosis factor [GO:0034612]; toxin transport [GO:1901998] adherens junction [GO:0005912]; axon [GO:0030424]; cell surface [GO:0009986]; clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle [GO:0005798]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum [GO:0097038]; plasma membrane [GO:0005886]; pore complex [GO:0046930]; postsynaptic density [GO:0014069]; specific granule membrane [GO:0035579]; synaptic membrane [GO:0097060]; tertiary granule membrane [GO:0070821]; tetraspanin-enriched microdomain [GO:0097197] endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; metallodipeptidase activity [GO:0070573]; metalloendopeptidase activity [GO:0004222]; metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902945]; metallopeptidase activity [GO:0008237]; molecular adaptor activity [GO:0060090]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; SH3 domain binding [GO:0017124]; signaling receptor binding [GO:0005102] 0.57488 0.47517 LVDADGPLAR 0 0 0 0 0 0 0 0 0 0 0 9.21888 11.1847 10.9362 0 0 11.45 0 0 0 0 0 0 0 0 0 0 O14678 ABCD4_HUMAN Lysosomal cobalamin transporter ABCD4 (EC 7.6.2.8) (ATP-binding cassette sub-family D member 4) (PMP70-related protein) (P70R) (Peroxisomal membrane protein 1-like) (PXMP1-L) (Peroxisomal membrane protein 69) (PMP69) ABCD4 PXMP1L Homo sapiens (Human) cellular response to leukemia inhibitory factor [GO:1990830]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid import into peroxisome [GO:0015910]; peroxisome organization [GO:0007031]; transmembrane transport [GO:0055085]; very long-chain fatty acid catabolic process [GO:0042760] ATP-binding cassette (ABC) transporter complex [GO:0043190]; endoplasmic reticulum membrane [GO:0005789]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777] ABC-type vitamin B12 transporter activity [GO:0015420]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]; identical protein binding [GO:0042802]; long-chain fatty acid transporter activity [GO:0005324] 0.83007 0.2046 DLTEHLHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.48047 0 0 0 0 O14681 EI24_HUMAN Etoposide-induced protein 2.4 homolog (p53-induced gene 8 protein) EI24 PIG8 Homo sapiens (Human) apoptotic process [GO:0006915]; macroautophagy [GO:0016236]; negative regulation of cell growth [GO:0030308] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nuclear membrane [GO:0031965] importin-alpha family protein binding [GO:0061676] 0.96944 -3.052 GIKDSIWGICTISK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.86409 9.55894 0 0 0 O14682 ENC1_HUMAN Ectoderm-neural cortex protein 1 (ENC-1) (Kelch-like protein 37) (Nuclear matrix protein NRP/B) (p53-induced gene 10 protein) ENC1 KLHL37 NRPB PIG10 Homo sapiens (Human) negative regulation of translation [GO:0017148]; nervous system development [GO:0007399]; positive regulation of neuron projection development [GO:0010976]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; protein ubiquitination [GO:0016567] chromatin [GO:0000785]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; neuronal cell body [GO:0043025]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] actin binding [GO:0003779] 0.88406 -0.16312 DACAEFLEK 0 8.90433 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O14684 PTGES_HUMAN Prostaglandin E synthase (EC 5.3.99.3) (Glutathione peroxidase PTGES) (EC 1.11.1.-) (Glutathione transferase PTGES) (EC 2.5.1.18) (Microsomal glutathione S-transferase 1-like 1) (MGST1-L1) (Microsomal prostaglandin E synthase 1) (MPGES-1) (p53-induced gene 12 protein) PTGES MGST1L1 MPGES1 PGES PIG12 Homo sapiens (Human) cell population proliferation [GO:0008283]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of prostaglandin secretion [GO:0032308]; prostaglandin biosynthetic process [GO:0001516]; prostaglandin metabolic process [GO:0006693]; regulation of fever generation [GO:0031620]; regulation of inflammatory response [GO:0050727]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165] endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]; perinuclear region of cytoplasm [GO:0048471] glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; prostaglandin-D synthase activity [GO:0004667]; prostaglandin-E synthase activity [GO:0050220] 0.035088 1.524 AFANPEDALR 0 0 0 0 0 0 8.97668 0 9.58742 10.0261 9.6619 0 9.7904 0 10.0107 10.5703 10.5909 0 0 0 0 0 0 0 0 0 0 O14686 KMT2D_HUMAN Histone-lysine N-methyltransferase 2D (Lysine N-methyltransferase 2D) (EC 2.1.1.364) (ALL1-related protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 2) KMT2D ALR MLL2 MLL4 Homo sapiens (Human) beta-catenin-TCF complex assembly [GO:1904837]; heterochromatin formation [GO:0031507]; histone H3-K4 methylation [GO:0051568]; oocyte growth [GO:0001555]; oogenesis [GO:0048477]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; response to estrogen [GO:0043627] MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; histone binding [GO:0042393]; histone H3K4 methyltransferase activity [GO:0042800]; histone H3K4 monomethyltransferase activity [GO:0140945]; histone H3K4 trimethyltransferase activity [GO:0140999]; metal ion binding [GO:0046872]; transcription cis-regulatory region binding [GO:0000976]; transcription coactivator activity [GO:0003713] 0.94556 -1.3426 AAHRINKVQK 10.6262 11.1896 11.6305 10.2999 0 10.863 12.3132 12.9872 0 11.7172 11.651 11.7703 0 0 0 10.7912 10.5773 9.96593 0 8.50803 0 10.6284 0 0 0 9.45222 0 O14709 ZN197_HUMAN Zinc finger protein 197 (Zinc finger protein with KRAB and SCAN domains 9) (ZnF20) (pVHL-associated KRAB domain-containing protein) ZNF197 ZKSCAN9 ZNF166 Homo sapiens (Human) nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.5638 0.51152 AFSYNSSLLVHR 0 0 8.50863 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1266 0 15.4849 0 0 0 0 0 0 0 8.34983 O14718 OPSX_HUMAN Visual pigment-like receptor peropsin RRH Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; phototransduction [GO:0007602]; visual perception [GO:0007601] photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; photoreceptor activity [GO:0009881] 0.93913 -1.3211 FRRAMLAMFK 0 0 0 0 0 0 9.94423 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O14727 APAF_HUMAN Apoptotic protease-activating factor 1 (APAF-1) APAF1 KIAA0413 Homo sapiens (Human) activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584] apoptosome [GO:0043293]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774] ADP binding [GO:0043531]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166] 0.96567 -2.3614 DKSVTDSVMGPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.2781 9.68909 0 9.60346 0 11.9226 0 0 0 0 O14730 RIOK3_HUMAN Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog) RIOK3 SUDD Homo sapiens (Human) cellular response to dsDNA [GO:1990786]; cellular response to dsRNA [GO:0071359]; cellular response to virus [GO:0098586]; chromosome segregation [GO:0007059]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; maturation of SSU-rRNA [GO:0030490]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of MDA-5 signaling pathway [GO:0039534]; negative regulation of protein-containing complex assembly [GO:0031333]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728]; protein phosphorylation [GO:0006468] "cytosol [GO:0005829]; preribosome, small subunit precursor [GO:0030688]" ATP binding [GO:0005524]; caspase binding [GO:0089720]; metal ion binding [GO:0046872]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.84782 0.12374 MVNSGMLETITGCISTGK 0 0 0 0 0 0 0 0 0 0 0 0 0 8.75395 0 0 0 0 0 0 0 0 0 0 0 0 0 O14733 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 (MAP kinase kinase 7) (MAPKK 7) (EC 2.7.12.2) (JNK-activating kinase 2) (MAPK/ERK kinase 7) (MEK 7) (Stress-activated protein kinase kinase 4) (SAPK kinase 4) (SAPKK-4) (SAPKK4) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2) MAP2K7 JNKK2 MEK7 MKK7 PRKMK7 SKK4 Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to osmotic stress [GO:0071470]; cellular response to sorbitol [GO:0072709]; cellular senescence [GO:0090398]; Fc-epsilon receptor signaling pathway [GO:0038095]; JNK cascade [GO:0007254]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein phosphorylation [GO:0006468]; regulation of motor neuron apoptotic process [GO:2000671]; response to heat [GO:0009408]; response to osmotic stress [GO:0006970]; response to tumor necrosis factor [GO:0034612]; response to UV [GO:0009411]; response to wounding [GO:0009611]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] ATP binding [GO:0005524]; enzyme binding [GO:0019899]; JUN kinase kinase activity [GO:0008545]; magnesium ion binding [GO:0000287]; MAP kinase activity [GO:0004707]; MAP kinase kinase activity [GO:0004708]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; molecular function activator activity [GO:0140677]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein serine kinase activity [GO:0106310]; protein tyrosine kinase activity [GO:0004713] 0.91651 -0.76952 DVMAKTESPR 0 0 0 0 0 0 0 0 0 0 0 9.37454 0 0 0 0 0 0 0 0 0 0 0 0 9.65703 0 0 O14734 ACOT8_HUMAN Acyl-coenzyme A thioesterase 8 (Acyl-CoA thioesterase 8) (EC 3.1.2.1) (EC 3.1.2.11) (EC 3.1.2.2) (EC 3.1.2.3) (EC 3.1.2.5) (Choloyl-coenzyme A thioesterase) (EC 3.1.2.27) (HIV-Nef-associated acyl-CoA thioesterase) (Peroxisomal acyl-CoA thioesterase 2) (PTE-2) (Peroxisomal acyl-coenzyme A thioester hydrolase 1) (PTE-1) (Peroxisomal long-chain acyl-CoA thioesterase 1) (Thioesterase II) (hACTE-III) (hACTEIII) (hTE) ACOT8 ACTEIII PTE1 Homo sapiens (Human) acyl-CoA metabolic process [GO:0006637]; alpha-linolenic acid metabolic process [GO:0036109]; bile acid biosynthetic process [GO:0006699]; dicarboxylic acid catabolic process [GO:0043649]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; fatty acid catabolic process [GO:0009062]; negative regulation of CD4 production [GO:0045225]; peroxisome fission [GO:0016559] cytosol [GO:0005829]; peroxisomal matrix [GO:0005782] acetoacetyl-CoA hydrolase activity [GO:0047603]; acetyl-CoA hydrolase activity [GO:0003986]; acyl-CoA hydrolase activity [GO:0047617]; carboxylic ester hydrolase activity [GO:0052689]; choloyl-CoA hydrolase activity [GO:0033882]; CoA hydrolase activity [GO:0016289]; glutaryl-CoA hydrolase activity [GO:0044466]; hydroxymethylglutaryl-CoA hydrolase activity [GO:0047994]; medium-chain acyl-CoA hydrolase activity [GO:0052815]; myristoyl-CoA hydrolase activity [GO:0102991]; palmitoyl-CoA hydrolase activity [GO:0016290]; succinyl-CoA hydrolase activity [GO:0004778] 0.84252 0.14992 GDPPGDLR 0 0 0 0 0 0 0 0 0 13.0603 13.3907 13.203 0 11.8596 12.23 0 12.7609 0 0 0 0 0 0 0 0 0 0 O14745 NHRF1_HUMAN Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (NHERF-1) (Ezrin-radixin-moesin-binding phosphoprotein 50) (EBP50) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform A3 regulatory factor 1) NHERF1 NHERF SLC9A3R1 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; auditory receptor cell stereocilium organization [GO:0060088]; bile acid secretion [GO:0032782]; cerebrospinal fluid circulation [GO:0090660]; cilium organization [GO:0044782]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; fibroblast migration [GO:0010761]; gamma-aminobutyric acid import [GO:0051939]; gland morphogenesis [GO:0022612]; glutathione transport [GO:0034635]; import across plasma membrane [GO:0098739]; intracellular phosphate ion homeostasis [GO:0030643]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; microvillus assembly [GO:0030033]; morphogenesis of an epithelium [GO:0002009]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sodium:proton antiporter activity [GO:0032416]; nuclear migration [GO:0007097]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; plasma membrane organization [GO:0007009]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of monoatomic ion transmembrane transport [GO:0034767]; protein localization to plasma membrane [GO:0072659]; protein-containing complex assembly [GO:0065003]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of protein kinase activity [GO:0045859]; regulation of renal phosphate excretion [GO:1903402]; renal absorption [GO:0070293]; renal phosphate ion absorption [GO:0097291]; renal sodium ion transport [GO:0003096]; sensory perception of sound [GO:0007605]; transport across blood-brain barrier [GO:0150104]; Wnt signaling pathway [GO:0016055] actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane protein complex [GO:0098797]; ruffle [GO:0001726]; sperm midpiece [GO:0097225]; stereocilium tip [GO:0032426]; vesicle [GO:0031982] beta-2 adrenergic receptor binding [GO:0031698]; beta-catenin binding [GO:0008013]; channel activator activity [GO:0099103]; chloride channel regulator activity [GO:0017081]; dopamine receptor binding [GO:0050780]; gamma-aminobutyric acid transmembrane transporter activity [GO:0015185]; growth factor receptor binding [GO:0070851]; identical protein binding [GO:0042802]; myosin II binding [GO:0045159]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein self-association [GO:0043621]; protein-containing complex binding [GO:0044877]; protein-membrane adaptor activity [GO:0043495]; signaling receptor binding [GO:0005102]; transmembrane transporter binding [GO:0044325]; type 2 metabotropic glutamate receptor binding [GO:0031799]; type 3 metabotropic glutamate receptor binding [GO:0031800] 0.10654 1.1619 AGLLAGDR 0 15.2371 0 0 0 0 0 0 0 8.99724 0 0 0 0 0 0 0 12.189 0 0 0 9.81798 10.4052 0 0 0 0 O14746 TERT_HUMAN Telomerase reverse transcriptase (EC 2.7.7.49) (HEST2) (Telomerase catalytic subunit) (Telomerase-associated protein 2) (TP2) TERT EST2 TCS1 TRT Homo sapiens (Human) cellular response to hypoxia [GO:0071456]; DNA biosynthetic process [GO:0071897]; DNA strand elongation [GO:0022616]; establishment of protein localization to telomere [GO:0070200]; mitochondrion organization [GO:0007005]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of angiogenesis [GO:0045766]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of glucose import [GO:0046326]; positive regulation of hair cycle [GO:0042635]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to nucleolus [GO:1904751]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transdifferentiation [GO:1903620]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of protein stability [GO:0031647]; replicative senescence [GO:0090399]; response to cadmium ion [GO:0046686]; RNA-templated DNA biosynthetic process [GO:0006278]; RNA-templated transcription [GO:0001172]; siRNA processing [GO:0030422]; siRNA transcription [GO:0140745]; telomere maintenance [GO:0000723]; telomere maintenance via telomerase [GO:0007004] "chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; mitochondrial nucleoid [GO:0042645]; nuclear speck [GO:0016607]; nuclear telomere cap complex [GO:0000783]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; RNA-directed RNA polymerase complex [GO:0031379]; telomerase catalytic core complex [GO:0000333]; telomerase holoenzyme complex [GO:0005697]; TERT-RMRP complex [GO:1990572]" DNA binding [GO:0003677]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein-folding chaperone binding [GO:0051087]; RNA binding [GO:0003723]; RNA-dependent RNA polymerase activity [GO:0003968]; RNA-directed DNA polymerase activity [GO:0003964]; telomerase activity [GO:0003720]; telomerase RNA binding [GO:0070034]; telomerase RNA reverse transcriptase activity [GO:0003721]; telomeric DNA binding [GO:0042162]; template-free RNA nucleotidyltransferase [GO:0098680]; transcription coactivator binding [GO:0001223]; tRNA binding [GO:0000049] 0.96831 -3.6247 KSVWSKLQSIGIR 0 0 0 0 0 0 0 0 0 0 0 0 11.6645 0 0 0 0 10.299 0 0 0 0 0 0 0 0 10.4414 O14757 CHK1_HUMAN Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1) CHEK1 CHK1 Homo sapiens (Human) "apoptotic process [GO:0006915]; apoptotic process involved in development [GO:1902742]; cellular response to caffeine [GO:0071313]; cellular response to mechanical stimulus [GO:0071260]; chromatin remodeling [GO:0006338]; DNA damage checkpoint signaling [GO:0000077]; DNA damage response [GO:0006974]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G2/M transition of mitotic cell cycle [GO:0000086]; inner cell mass cell proliferation [GO:0001833]; intracellular signal transduction [GO:0035556]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; mitotic G2/M transition checkpoint [GO:0044818]; negative regulation of DNA biosynthetic process [GO:2000279]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of mitotic nuclear division [GO:0045839]; nucleus organization [GO:0006997]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cell cycle [GO:0045787]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of mitotic centrosome separation [GO:0046602]; regulation of signal transduction by p53 class mediator [GO:1901796]; replicative senescence [GO:0090399]; signal transduction in response to DNA damage [GO:0042770]" centrosome [GO:0005813]; chromatin [GO:0000785]; condensed nuclear chromosome [GO:0000794]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; replication fork [GO:0005657] ATP binding [GO:0005524]; histone H3T11 kinase activity [GO:0035402]; protein domain specific binding [GO:0019904]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.95512 -1.6044 ISDFGLATVFR 0 0 0 0 0 0 0 11.641 0 11.9336 11.9844 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O14763 TR10B_HUMAN Tumor necrosis factor receptor superfamily member 10B (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD antigen CD262) TNFRSF10B DR5 KILLER TRAILR2 TRICK2 ZTNFR9 UNQ160/PRO186 Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; defense response to tumor cell [GO:0002357]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of apoptotic process [GO:0042981]; response to endoplasmic reticulum stress [GO:0034976]; TRAIL-activated apoptotic signaling pathway [GO:0036462] cell surface [GO:0009986]; plasma membrane [GO:0005886] signaling receptor activity [GO:0038023]; TRAIL binding [GO:0045569]; TRAIL receptor activity [GO:0036463] 0.88952 -0.45476 AEAAGHR 0 0 0 0 0 0 0 0 0 0 0 9.24985 0 9.7134 0 0 0 0 0 0 0 0 0 0 0 10.1187 0 O14764 GBRD_HUMAN Gamma-aminobutyric acid receptor subunit delta (GABA(A) receptor subunit delta) GABRD Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; monoatomic ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] axon [GO:0030424]; chloride channel complex [GO:0034707]; dendrite [GO:0030425]; GABA-A receptor complex [GO:1902711]; GABA-ergic synapse [GO:0098982]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202] chloride channel activity [GO:0005254]; GABA-A receptor activity [GO:0004890]; neurotransmitter receptor activity [GO:0030594]; transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315] 0.87184 0.064881 ITSTVACDMDLAK 0 8.43667 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O14776 TCRG1_HUMAN Transcription elongation regulator 1 (TATA box-binding protein-associated factor 2S) (Transcription factor CA150) TCERG1 CA150 TAF2S Homo sapiens (Human) mRNA processing [GO:0006397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; RNA splicing [GO:0008380] nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase binding [GO:0070063]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription corepressor activity [GO:0003714]; transcription elongation factor activity [GO:0003711]; ubiquitin-like protein conjugating enzyme binding [GO:0044390] 0.96785 -3.7348 EDPRCIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2215 0 0 0 10.112 0 O14777 NDC80_HUMAN Kinetochore protein NDC80 homolog (Highly expressed in cancer protein) (Kinetochore protein Hec1) (HsHec1) (Kinetochore-associated protein 2) (Retinoblastoma-associated protein HEC) NDC80 HEC HEC1 KNTC2 Homo sapiens (Human) attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; attachment of spindle microtubules to kinetochore [GO:0008608]; cell division [GO:0051301]; centrosome duplication [GO:0051298]; chromosome segregation [GO:0007059]; establishment of mitotic spindle orientation [GO:0000132]; G2/MI transition of meiotic cell cycle [GO:0008315]; kinetochore organization [GO:0051383]; metaphase plate congression [GO:0051310]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint signaling [GO:0007094]; mitotic spindle organization [GO:0007052]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; regulation of protein stability [GO:0031647]; spindle assembly involved in female meiosis I [GO:0007057] "centrosome [GO:0005813]; chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; kinetochore [GO:0000776]; membrane [GO:0016020]; Ndc80 complex [GO:0031262]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; outer kinetochore [GO:0000940]" cyclin binding [GO:0030332]; identical protein binding [GO:0042802]; kinetochore adaptor activity [GO:0140483] 0.96322 -2.1462 DLFNVDAFK 0 0 0 0 0 10.788 11.0662 0 0 0 0 0 0 0 0 0 0 0 0 0 9.35255 0 0 0 0 0 0 O14782 KIF3C_HUMAN Kinesin-like protein KIF3C KIF3C Homo sapiens (Human) microtubule-based movement [GO:0007018] ciliary tip [GO:0097542]; cilium [GO:0005929]; cytosol [GO:0005829]; kinesin complex [GO:0005871]; microtubule [GO:0005874] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; cytoskeletal motor activity [GO:0003774]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777] 0.92416 -0.99107 AAPGELPK 0 0 0 10.7715 0 9.63203 0 0 0 0 0 0 0 0 10.255 10.5788 0 0 0 0 0 0 0 9.49368 0 0 0 O14786 NRP1_HUMAN Neuropilin-1 (Vascular endothelial cell growth factor 165 receptor) (CD antigen CD304) NRP1 NRP VEGF165R Homo sapiens (Human) "angiogenesis [GO:0001525]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; animal organ morphogenesis [GO:0009887]; artery morphogenesis [GO:0048844]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; basal dendrite development [GO:0150018]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell-cell signaling [GO:0007267]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; endothelial tip cell fate specification [GO:0097102]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; neural crest cell migration [GO:0001755]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; neuron migration [GO:0001764]; neuropilin signaling pathway [GO:0038189]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytokine activity [GO:0060301]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030947]; regulation of vesicle-mediated transport [GO:0060627]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; retinal ganglion cell axon guidance [GO:0031290]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]; viral entry into host cell [GO:0046718]" axon [GO:0030424]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; mitochondrial membrane [GO:0031966]; neurofilament [GO:0005883]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; receptor complex [GO:0043235]; semaphorin receptor complex [GO:0002116]; sorting endosome [GO:0097443] coreceptor activity [GO:0015026]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor receptor activity [GO:0005021] 0.36703 0.74193 IDVSSNGEDWITIK 10.0806 0 10.0639 0 0 9.5308 0 0 10.2713 0 11.3921 11.2153 10.3372 0 0 0 9.42844 11.6161 0 0 0 0 9.84105 0 0 0 0 O14787 TNPO2_HUMAN Transportin-2 (Karyopherin beta-2b) TNPO2 Homo sapiens (Human) protein import into nucleus [GO:0006606] cytoplasm [GO:0005737]; nucleus [GO:0005634] nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; small GTPase binding [GO:0031267] 0.82959 0.20925 LAAFYGV 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.48718 0 0 0 0 0 0 O14795 UN13B_HUMAN Protein unc-13 homolog B (Munc13-2) (munc13) UNC13B UNC13 Homo sapiens (Human) "acrosomal vesicle exocytosis [GO:0060478]; cellular response to glucose stimulus [GO:0071333]; chemical synaptic transmission [GO:0007268]; dense core granule priming [GO:0061789]; neuromuscular junction development [GO:0007528]; neuronal dense core vesicle exocytosis [GO:0099011]; positive regulation of apoptotic process [GO:0043065]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of protein secretion [GO:0050714]; positive regulation of synaptic vesicle priming [GO:0010808]; presynaptic dense core vesicle exocytosis [GO:0099525]; synaptic transmission, glutamatergic [GO:0035249]; synaptic vesicle docking [GO:0016081]; synaptic vesicle maturation [GO:0016188]; synaptic vesicle priming [GO:0016082]" cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; plasma membrane [GO:0005886]; presynaptic active zone [GO:0048786]; presynaptic active zone cytoplasmic component [GO:0098831]; presynaptic membrane [GO:0042734]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195] calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; diacylglycerol binding [GO:0019992]; GTP-dependent protein binding [GO:0030742]; phospholipid binding [GO:0005543]; small GTPase binding [GO:0031267]; syntaxin-1 binding [GO:0017075] 0.96937 -3.4925 AHWIRAVTK 0 0 0 0 0 0 0 0 9.34702 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O14802 RPC1_HUMAN DNA-directed RNA polymerase III subunit RPC1 (RNA polymerase III subunit C1) (EC 2.7.7.6) (DNA-directed RNA polymerase III largest subunit) (DNA-directed RNA polymerase III subunit A) (RNA polymerase III 155 kDa subunit) (RPC155) (RNA polymerase III subunit C160) POLR3A Homo sapiens (Human) defense response to virus [GO:0051607]; DNA-templated transcription [GO:0006351]; innate immune response [GO:0045087]; positive regulation of interferon-beta production [GO:0032728]; transcription by RNA polymerase III [GO:0006383] cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase III complex [GO:0005666] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; metal ion binding [GO:0046872] 0.96385 -2.4117 FLETCRDK 0 0 0 0 0 0 9.70155 9.98214 0 0 10.481 0 0 0 0 0 9.02201 10.0031 0 0 0 0 0 0 0 0 0 O14815 CAN9_HUMAN Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (New calpain 4) (nCL-4) (Protein CG36) CAPN9 NCL4 Homo sapiens (Human) digestion [GO:0007586]; proteolysis [GO:0006508] cytoplasm [GO:0005737] calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198] 0.90742 -0.73795 EVSDRFK 0 0 0 0 9.5742 9.89241 0 0 0 8.75662 10.2667 0 9.95434 9.86158 0 11.1742 10.5704 0 0 8.15386 0 0 0 0 0 0 0 O14827 RGRF2_HUMAN Ras-specific guanine nucleotide-releasing factor 2 (Ras-GRF2) (Ras guanine nucleotide exchange factor 2) RASGRF2 GRF2 Homo sapiens (Human) long-term synaptic potentiation [GO:0060291]; positive regulation of GTPase activity [GO:0043547]; Ras protein signal transduction [GO:0007265]; regulation of NMDA receptor activity [GO:2000310]; regulation of small GTPase mediated signal transduction [GO:0051056]; response to endoplasmic reticulum stress [GO:0034976] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; plasma membrane [GO:0005886] calmodulin binding [GO:0005516]; guanyl-nucleotide exchange factor activity [GO:0005085] 0.96729 -3.7504 SDARLHKDDTDICFSK 0 0 11.5122 0 0 0 0 0 0 0 0 0 0 0 10.5039 0 0 0 9.49599 0 0 0 0 0 0 0 0 O14829 PPE1_HUMAN Serine/threonine-protein phosphatase with EF-hands 1 (PPEF-1) (EC 3.1.3.16) (Protein phosphatase with EF calcium-binding domain) (PPEF) (Serine/threonine-protein phosphatase 7) (PP7) PPEF1 PPEF PPP7C Homo sapiens (Human) detection of stimulus involved in sensory perception [GO:0050906]; protein dephosphorylation [GO:0006470] cytosol [GO:0005829]; nucleus [GO:0005634] calcium ion binding [GO:0005509]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; myosin phosphatase activity [GO:0017018]; protein serine/threonine phosphatase activity [GO:0004722] 0.96231 -2.5511 RSDTSLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.0846 0 O14832 PAHX_HUMAN "Phytanoyl-CoA dioxygenase, peroxisomal (EC 1.14.11.18) (Phytanic acid oxidase) (Phytanoyl-CoA alpha-hydroxylase) (PhyH)" PHYH PAHX Homo sapiens (Human) 2-oxobutyrate catabolic process [GO:0019606]; 2-oxoglutarate metabolic process [GO:0006103]; fatty acid alpha-oxidation [GO:0001561]; isoprenoid metabolic process [GO:0006720]; methyl-branched fatty acid metabolic process [GO:0097089] 9+0 non-motile cilium [GO:0097731]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777] carboxylic acid binding [GO:0031406]; ferrous iron binding [GO:0008198]; L-ascorbic acid binding [GO:0031418]; phytanoyl-CoA dioxygenase activity [GO:0048244] 0.96707 -2.3162 DIWMFRAR 0 0 0 0 0 0 0 0 0 0 9.40716 0 0 8.74147 0 0 0 0 0 0 0 0 0 0 0 0 0 O14842 FFAR1_HUMAN Free fatty acid receptor 1 (G-protein coupled receptor 40) FFAR1 GPR40 Homo sapiens (Human) "G protein-coupled receptor signaling pathway [GO:0007186]; glucose homeostasis [GO:0042593]; insulin secretion [GO:0030073]; ion channel modulating, G protein-coupled receptor signaling pathway [GO:0099105]; ligand-gated ion channel signaling pathway [GO:1990806]; negative regulation of interleukin-1 beta production [GO:0032691]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; response to fatty acid [GO:0070542]" plasma membrane [GO:0005886] bioactive lipid receptor activity [GO:0045125]; G protein-coupled receptor activity [GO:0004930]; GTPase activator activity [GO:0005096]; lipid binding [GO:0008289] 0.65175 0.39585 GATAHAR 0 0 0 0 0 0 9.65664 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0108 0 10.2614 10.1435 0 0 12.2349 O14862 AIM2_HUMAN Interferon-inducible protein AIM2 (Absent in melanoma 2) AIM2 Homo sapiens (Human) activation of innate immune response [GO:0002218]; AIM2 inflammasome complex assembly [GO:0140970]; brain development [GO:0007420]; cellular response to interferon-beta [GO:0035458]; cellular response to xenobiotic stimulus [GO:0071466]; defense response to virus [GO:0051607]; DNA damage response [GO:0006974]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein kinase B signaling [GO:0051898]; neuron cellular homeostasis [GO:0070050]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; pyroptosis [GO:0070269]; pyroptosome complex assembly [GO:1904270]; regulation of behavior [GO:0050795]; T cell homeostasis [GO:0043029]; tumor necrosis factor-mediated signaling pathway [GO:0033209] AIM2 inflammasome complex [GO:0097169]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; site of double-strand break [GO:0035861] cysteine-type endopeptidase activator activity [GO:0140608]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; pattern recognition receptor activity [GO:0038187]; signaling adaptor activity [GO:0035591]; signaling receptor activator activity [GO:0030546] 0.92592 -1.2113 LNYMLLAK 0 0 9.49047 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O14863 ZNT4_HUMAN Probable proton-coupled zinc antiporter SLC30A4 (Solute carrier family 30 member 4) (Zinc transporter 4) (ZnT-4) SLC30A4 ZNT4 Homo sapiens (Human) regulation of sequestering of zinc ion [GO:0061088]; response to toxic substance [GO:0009636]; response to zinc ion [GO:0010043]; zinc export across plasma membrane [GO:0140882]; zinc ion transmembrane transport [GO:0071577] cytoplasm [GO:0005737]; endosome membrane [GO:0010008]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886] antiporter activity [GO:0015297]; metal ion binding [GO:0046872]; zinc ion transmembrane transporter activity [GO:0005385] 0.64928 0.39598 AGSGAWK 0 0 0 0 0 0 0 0 0 0 0 0 8.37443 0 8.63854 0 8.86189 0 0 0 0 0 0 0 0 0 0 O14867 BACH1_HUMAN Transcription regulator protein BACH1 (BTB and CNC homolog 1) (HA2303) BACH1 Homo sapiens (Human) DNA repair [GO:0006281]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355]; regulation of metabolic process [GO:0019222]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; regulation of transcription involved in G2/M transition of mitotic cell cycle [GO:0000117] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; heme binding [GO:0020037]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.95982 -1.7271 CDESKLAMEPEETKK 0 0 0 0 0 0 0 0 9.2274 0 0 0 0 9.32681 0 0 0 14.1272 0 0 0 0 0 0 0 0 0 O14874 BCKD_HUMAN "[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial (EC 2.7.11.4) (Branched-chain alpha-ketoacid dehydrogenase kinase) (BCKD-kinase) (BCKDHKIN)" BCKDK Homo sapiens (Human) amino acid catabolic process [GO:0009063]; branched-chain amino acid catabolic process [GO:0009083]; negative regulation of cellular amino acid metabolic process [GO:0045763]; phosphorylation [GO:0016310]; protein phosphorylation [GO:0006468]; regulation of glucose metabolic process [GO:0010906] mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity [GO:0047323]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; protein serine/threonine kinase activity [GO:0004674]; pyruvate dehydrogenase (acetyl-transferring) kinase activity [GO:0004740] 0.77357 0.27179 LTDFPPIK 0 10.128 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O14879 IFIT3_HUMAN Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) (CIG49) (ISG-60) (Interferon-induced 60 kDa protein) (IFI-60K) (Interferon-induced protein with tetratricopeptide repeats 4) (IFIT-4) (Retinoic acid-induced gene G protein) (P60) (RIG-G) IFIT3 CIG-49 IFI60 IFIT4 ISG60 Homo sapiens (Human) antiviral innate immune response [GO:0140374]; defense response to virus [GO:0051607]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; response to virus [GO:0009615] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739] identical protein binding [GO:0042802] 0.9214 -1.1142 LSDAQIYVDK 0 0 0 0 0 0 0 0 0 9.32708 0 0 0 0 0 0 10.1496 0 0 0 0 0 0 0 0 0 0 O14893 GEMI2_HUMAN Gem-associated protein 2 (Gemin-2) (Component of gems 2) (Survival of motor neuron protein-interacting protein 1) (SMN-interacting protein 1) GEMIN2 SIP1 Homo sapiens (Human) "mRNA processing [GO:0006397]; negative regulation of RNA binding [GO:1905215]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal complex assembly [GO:0000245]; spliceosomal snRNP assembly [GO:0000387]" cytosol [GO:0005829]; Gemini of coiled bodies [GO:0097504]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SMN complex [GO:0032797]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681] 0.93296 -1.2657 QNVNKHRSHWK 0 0 0 0 0 0 0 0 0 8.97651 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O14894 T4S5_HUMAN Transmembrane 4 L6 family member 5 (Tetraspan transmembrane protein L6H) TM4SF5 Homo sapiens (Human) cell cycle [GO:0007049]; regulation of G1/S transition of mitotic cell cycle [GO:2000045] lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886] arginine binding [GO:0034618] 0.93379 -1.2804 GCCGAGCCGNRCR 0 9.70389 0 0 0 0 9.87123 0 9.65603 10.1904 9.93044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O14896 IRF6_HUMAN Interferon regulatory factor 6 (IRF-6) IRF6 Homo sapiens (Human) cell development [GO:0048468]; cranial skeletal system development [GO:1904888]; immune system process [GO:0002376]; keratinocyte differentiation [GO:0030216]; keratinocyte proliferation [GO:0043616]; limb development [GO:0060173]; mammary gland epithelial cell differentiation [GO:0060644]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of stem cell proliferation [GO:2000647]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; roof of mouth development [GO:0060021]; stem cell proliferation [GO:0072089] cell junction [GO:0030054]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.92438 -1.0027 DNIVAQLKQLYR 10.7142 10.6407 12.0886 0 0 0 0 0 0 0 10.3939 12.6352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O14904 WNT9A_HUMAN Protein Wnt-9a (Protein Wnt-14) WNT9A WNT14 Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cornea development in camera-type eye [GO:0061303]; embryonic skeletal joint development [GO:0072498]; iris morphogenesis [GO:0061072]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chondrocyte differentiation [GO:0032331]; neuron differentiation [GO:0030182] extracellular region [GO:0005576]; extracellular space [GO:0005615] cytokine activity [GO:0005125]; frizzled binding [GO:0005109]; receptor ligand activity [GO:0048018] 0.92128 -1.1048 QLAPFHEVGKHLKHK 0 0 0 0 0 0 0 0 0 10.6159 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O14905 WNT9B_HUMAN Protein Wnt-9b (Protein Wnt-14b) (Protein Wnt-15) WNT9B WNT14B WNT15 UNQ6973/PRO21956 Homo sapiens (Human) "branching involved in ureteric bud morphogenesis [GO:0001658]; canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to starvation [GO:0009267]; collecting duct development [GO:0072044]; cornea development in camera-type eye [GO:0061303]; embryonic cranial skeleton morphogenesis [GO:0048701]; establishment of planar polarity involved in nephron morphogenesis [GO:0072046]; in utero embryonic development [GO:0001701]; kidney rudiment formation [GO:0072003]; male genitalia development [GO:0030539]; mesenchymal stem cell maintenance involved in nephron morphogenesis [GO:0072038]; mesonephric duct formation [GO:0072181]; metanephric tubule formation [GO:0072174]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of stem cell population maintenance [GO:1902455]; neuron differentiation [GO:0030182]; non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1905438]; positive regulation of catalytic activity [GO:0043085]; regulation of asymmetric cell division [GO:0009786]; regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003339]; regulation of protein phosphorylation [GO:0001932]; regulation of tube size [GO:0035150]; response to retinoic acid [GO:0032526]; roof of mouth development [GO:0060021]; uterus morphogenesis [GO:0061038]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" extracellular region [GO:0005576]; extracellular space [GO:0005615] co-receptor binding [GO:0039706]; cytokine activity [GO:0005125]; frizzled binding [GO:0005109]; receptor ligand activity [GO:0048018] 0.95358 -1.4982 HERWNCSLEGR 0 0 0 0 0 0 0 0 0 8.62201 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O14917 PCD17_HUMAN Protocadherin-17 (Protocadherin-68) PCDH17 PCDH68 PCH68 Homo sapiens (Human) adult behavior [GO:0030534]; cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of synaptic transmission [GO:0050805]; presynaptic active zone assembly [GO:1904071]; regulation of synaptic vesicle clustering [GO:2000807]; synaptic membrane adhesion [GO:0099560] GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734] calcium ion binding [GO:0005509] 0.34793 0.76857 GGGGRSK 0 0 0 0 0 0 0 0 14.0248 0 14.9477 0 0 0 11.3225 0 0 11.6818 0 0 0 0 0 0 0 0 0 O14924 RGS12_HUMAN Regulator of G-protein signaling 12 (RGS12) RGS12 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; regulation of G protein-coupled receptor signaling pathway [GO:0008277] condensed nuclear chromosome [GO:0000794]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202] GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; GTPase regulator activity [GO:0030695] 0.96923 -3.5711 SLSESAATR 0 0 0 0 0 0 0 0 0 0 0 0 9.36232 0 0 0 0 0 0 0 0 8.46606 0 0 0 0 0 O14926 FSCN2_HUMAN Fascin-2 (Retinal fascin) FSCN2 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; anatomical structure morphogenesis [GO:0009653]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; eye photoreceptor cell development [GO:0042462]; visual perception [GO:0007601] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; stereocilium [GO:0032420] actin binding [GO:0003779]; actin filament binding [GO:0051015]; protein-macromolecule adaptor activity [GO:0030674] 0.84962 0.16535 ACYTLEFK 0 0 0 0 0 0 0 0 0 0 9.50738 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O14936 CSKP_HUMAN Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog) CASK LIN2 Homo sapiens (Human) calcium ion import [GO:0070509]; cell adhesion [GO:0007155]; establishment of localization in cell [GO:0051649]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cellular response to growth factor stimulus [GO:0090288]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of wound healing [GO:0061045]; positive regulation of calcium ion import [GO:0090280]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of neurotransmitter secretion [GO:0046928]; regulation of synaptic vesicle exocytosis [GO:2000300] actin cytoskeleton [GO:0015629]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell-cell junction [GO:0005911]; ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nuclear lamina [GO:0005652]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; Schaffer collateral - CA1 synapse [GO:0098685]; vesicle [GO:0031982] ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; guanylate kinase activity [GO:0004385]; neurexin family protein binding [GO:0042043]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; signaling receptor binding [GO:0005102] 0.22865 0.87249 FTSSPGLSTEDLKR 0 9.08746 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5241 0 0 0 0 0 0 0 O14939 PLD2_HUMAN Phospholipase D2 (PLD 2) (hPLD2) (EC 3.1.4.4) (Choline phosphatase 2) (PLD1C) (Phosphatidylcholine-hydrolyzing phospholipase D2) PLD2 Homo sapiens (Human) cytoskeleton organization [GO:0007010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inositol lipid-mediated signaling [GO:0048017]; phosphatidic acid biosynthetic process [GO:0006654]; phospholipid catabolic process [GO:0009395]; regulation of vesicle-mediated transport [GO:0060627]; small GTPase mediated signal transduction [GO:0007264]; synaptic vesicle recycling [GO:0036465] endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; presynapse [GO:0098793] N-acylphosphatidylethanolamine-specific phospholipase D activity [GO:0070290]; phosphatidylinositol binding [GO:0035091]; phospholipase D activity [GO:0004630] 0.21994 0.88244 ALMLLHPNIK 0 0 0 10.3053 0 0 0 0 0 0 0 0 10.2178 10.2497 0 10.5068 0 0 0 0 0 0 0 0 0 0 0 O14944 EREG_HUMAN Proepiregulin [Cleaved into: Epiregulin (EPR)] EREG Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; cell-cell signaling [GO:0007267]; cytokine-mediated signaling pathway [GO:0019221]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2-EGFR signaling pathway [GO:0038134]; ERBB2-ERBB4 signaling pathway [GO:0038135]; ERBB4-ERBB4 signaling pathway [GO:0038138]; female meiotic nuclear division [GO:0007143]; keratinocyte differentiation [GO:0030216]; keratinocyte proliferation [GO:0043616]; luteinizing hormone signaling pathway [GO:0042700]; mRNA transcription [GO:0009299]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of smooth muscle cell differentiation [GO:0051151]; oocyte maturation [GO:0001556]; ovarian cumulus expansion [GO:0001550]; ovulation [GO:0030728]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production [GO:0001819]; positive regulation of DNA replication [GO:0045740]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of smooth muscle cell proliferation [GO:0048661]; primary follicle stage [GO:0048160]; response to peptide hormone [GO:0043434]; wound healing [GO:0042060] clathrin-coated endocytic vesicle membrane [GO:0030669]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] epidermal growth factor receptor binding [GO:0005154]; growth factor activity [GO:0008083]; receptor ligand activity [GO:0048018]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297] 0.95104 -1.3838 VAQVSITK 0 11.5463 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O14958 CASQ2_HUMAN "Calsequestrin-2 (Calsequestrin, cardiac muscle isoform)" CASQ2 Homo sapiens (Human) cardiac muscle contraction [GO:0060048]; cellular response to caffeine [GO:0071313]; detection of calcium ion [GO:0005513]; intracellular calcium ion homeostasis [GO:0006874]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; protein polymerization [GO:0051258]; Purkinje myocyte to ventricular cardiac muscle cell signaling [GO:0086029]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling [GO:0010649]; regulation of heart rate [GO:0002027]; regulation of membrane repolarization [GO:0060306]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; sequestering of calcium ion [GO:0051208]; striated muscle contraction [GO:0006941] calcium channel complex [GO:0034704]; cytoplasm [GO:0005737]; junctional sarcoplasmic reticulum membrane [GO:0014701]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum lumen [GO:0033018]; sarcoplasmic reticulum membrane [GO:0033017]; Z disc [GO:0030018] calcium ion binding [GO:0005509]; calcium ion sequestering activity [GO:0140314]; calcium-dependent protein binding [GO:0048306]; ion binding [GO:0043167]; protein homodimerization activity [GO:0042803] 0.96014 -1.8977 GVAKKLSLK 0 0 9.33358 0 0 0 0 0 0 0 0 0 9.65973 0 0 9.41821 0 0 9.95548 0 9.60509 0 0 0 0 0 0 O14960 LECT2_HUMAN Leukocyte cell-derived chemotaxin-2 (LECT-2) (hLECT2) LECT2 Homo sapiens (Human) chemotaxis [GO:0006935]; skeletal system development [GO:0001501] cytoplasm [GO:0005737]; extracellular space [GO:0005615] identical protein binding [GO:0042802]; metal ion binding [GO:0046872] 0.9414 -1.3126 ISGRGFCVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.70586 0 9.7802 0 0 0 0 0 O14964 HGS_HUMAN Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) (Protein pp110) HGS HRS Homo sapiens (Human) endocytic recycling [GO:0032456]; endosomal transport [GO:0016197]; macroautophagy [GO:0016236]; membrane fission [GO:0090148]; membrane invagination [GO:0010324]; multivesicular body assembly [GO:0036258]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of gene expression [GO:0010628]; protein localization to membrane [GO:0072657]; protein targeting to lysosome [GO:0006622]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; receptor internalization [GO:0031623]; regulation of MAP kinase activity [GO:0043405]; regulation of protein catabolic process [GO:0042176]; signal transduction [GO:0007165] cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; ESCRT-0 complex [GO:0033565]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; multivesicular body membrane [GO:0032585]; phagocytic vesicle lumen [GO:0097013] metal ion binding [GO:0046872]; phosphatidylinositol binding [GO:0035091]; protein domain specific binding [GO:0019904]; ubiquitin binding [GO:0043130]; ubiquitin-like protein ligase binding [GO:0044389] 0.96909 -4.212 ACGQIFCGKCSSK 0 8.7414 8.60655 0 0 0 0 0 8.53228 0 0 0 0 0 0 0 0 8.95181 0 0 10.2084 0 0 0 0 10.2915 0 O14965 AURKA_HUMAN Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (Breast tumor-amplified kinase) (Ipl1- and aurora-related kinase 1) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase Ayk1) (Serine/threonine-protein kinase aurora-A) AURKA AIK AIRK1 ARK1 AURA AYK1 BTAK IAK1 STK15 STK6 Homo sapiens (Human) anterior/posterior axis specification [GO:0009948]; apoptotic process [GO:0006915]; cell division [GO:0051301]; centrosome localization [GO:0051642]; cilium disassembly [GO:0061523]; G2/M transition of mitotic cell cycle [GO:0000086]; liver regeneration [GO:0097421]; mitotic cell cycle [GO:0000278]; mitotic centrosome separation [GO:0007100]; mitotic spindle organization [GO:0007052]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; negative regulation of protein binding [GO:0032091]; neuron projection extension [GO:1990138]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of oocyte maturation [GO:1900195]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autophosphorylation [GO:0046777]; protein localization to centrosome [GO:0071539]; protein phosphorylation [GO:0006468]; regulation of centrosome cycle [GO:0046605]; regulation of cytokinesis [GO:0032465]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to wounding [GO:0009611]; spindle assembly involved in female meiosis I [GO:0007057]; spindle organization [GO:0007051] axon hillock [GO:0043203]; basolateral plasma membrane [GO:0016323]; centriole [GO:0005814]; centrosome [GO:0005813]; chromosome passenger complex [GO:0032133]; ciliary basal body [GO:0036064]; cytosol [GO:0005829]; germinal vesicle [GO:0042585]; glutamatergic synapse [GO:0098978]; kinetochore [GO:0000776]; meiotic spindle [GO:0072687]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; mitotic spindle pole [GO:0097431]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; pronucleus [GO:0045120]; spindle [GO:0005819]; spindle midzone [GO:0051233]; spindle pole centrosome [GO:0031616] ATP binding [GO:0005524]; molecular function activator activity [GO:0140677]; protein heterodimerization activity [GO:0046982]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; ubiquitin protein ligase binding [GO:0031625] 0.96717 -2.316 AGVEHQLRR 0 0 0 0 0 0 0 0 0 9.44997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.456 O14966 RAB7L_HUMAN Ras-related protein Rab-7L1 (Rab-7-like protein 1) (Ras-related protein Rab-29) RAB29 RAB7L1 Homo sapiens (Human) "cell differentiation [GO:0030154]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; melanosome organization [GO:0032438]; mitochondrion organization [GO:0007005]; modulation by host of viral process [GO:0044788]; negative regulation of neuron projection development [GO:0010977]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of receptor recycling [GO:0001921]; positive regulation of T cell receptor signaling pathway [GO:0050862]; protein localization to ciliary membrane [GO:1903441]; protein localization to membrane [GO:0072657]; regulation of neuron death [GO:1901214]; regulation of retrograde transport, endosome to Golgi [GO:1905279]; response to bacterium [GO:0009617]; retrograde transport, endosome to Golgi [GO:0042147]; synapse assembly [GO:0007416]; T cell activation [GO:0042110]; toxin transport [GO:1901998]" cis-Golgi network [GO:0005801]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; intracellular vesicle [GO:0097708]; melanosome [GO:0042470]; mitochondrion [GO:0005739]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; trans-Golgi network [GO:0005802]; vacuole [GO:0005773] dynein complex binding [GO:0070840]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; kinesin binding [GO:0019894]; small GTPase binding [GO:0031267] 0.89795 -0.56466 DHLFKVLVVGDAAVGK 0 0 0 0 0 11.4477 0 0 0 0 0 0 0 10.0575 0 0 11.2299 0 0 0 0 0 0 0 0 0 0 O14967 CLGN_HUMAN Calmegin CLGN Homo sapiens (Human) binding of sperm to zona pellucida [GO:0007339]; protein folding [GO:0006457]; protein-containing complex assembly [GO:0065003]; single fertilization [GO:0007338]; ubiquitin-dependent ERAD pathway [GO:0030433] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789] calcium ion binding [GO:0005509]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082] 0.95136 -1.4348 HKHPKTGVFEEK 8.78293 0 0 0 10.395 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O14974 MYPT1_HUMAN Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit) PPP1R12A MBS MYPT1 Homo sapiens (Human) cellular response to xenobiotic stimulus [GO:0071466]; centrosome cycle [GO:0007098]; mitotic cell cycle [GO:0000278]; negative regulation of catalytic activity [GO:0043086]; positive regulation of myosin-light-chain-phosphatase activity [GO:0035508]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of myosin-light-chain-phosphatase activity [GO:0035507]; regulation of nucleocytoplasmic transport [GO:0046822]; signal transduction [GO:0007165] A band [GO:0031672]; actin cytoskeleton [GO:0015629]; centrosome [GO:0005813]; contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; kinetochore [GO:0000776]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; PTW/PP1 phosphatase complex [GO:0072357]; Z disc [GO:0030018] 14-3-3 protein binding [GO:0071889]; enzyme inhibitor activity [GO:0004857]; phosphatase regulator activity [GO:0019208]; protein kinase binding [GO:0019901] 0.96992 -5.0207 EGEKREEEK 0 0 0 0 0 0 0 0 10.8509 0 10.6889 8.43288 0 9.32557 0 0 0 0 0 11.1162 0 0 0 9.89341 0 11.6778 0 O14976 GAK_HUMAN Cyclin-G-associated kinase (EC 2.7.11.1) GAK Homo sapiens (Human) cell cycle [GO:0007049]; chaperone cofactor-dependent protein refolding [GO:0051085]; clathrin coat assembly [GO:0048268]; clathrin coat disassembly [GO:0072318]; clathrin-dependent endocytosis [GO:0072583]; endoplasmic reticulum organization [GO:0007029]; Golgi organization [GO:0007030]; Golgi to lysosome transport [GO:0090160]; negative regulation of neuron projection development [GO:0010977]; protein localization to Golgi apparatus [GO:0034067]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; receptor-mediated endocytosis [GO:0006898]; synaptic vesicle uncoating [GO:0016191] cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; presynapse [GO:0098793]; vesicle [GO:0031982] ATP binding [GO:0005524]; clathrin binding [GO:0030276]; cyclin binding [GO:0030332]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein-folding chaperone binding [GO:0051087] 0.96141 -2.5732 ALVEEEITR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0153 0 0 0 0 0 0 O14979 HNRDL_HUMAN Heterogeneous nuclear ribonucleoprotein D-like (hnRNP D-like) (hnRNP DL) (AU-rich element RNA-binding factor) (JKT41-binding protein) (Protein laAUF1) HNRNPDL HNRPDL JKTBP Homo sapiens (Human) regulation of gene expression [GO:0010468]; RNA processing [GO:0006396] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681] DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; poly(A) binding [GO:0008143]; poly(G) binding [GO:0034046]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697] 0.92227 -1.0857 GAAAGGR 8.83747 0 11.3665 0 0 0 9.28967 0 0 0 0 0 0 0 0 0 9.91606 0 0 0 0 10.377 0 10.6574 0 0 0 O14980 XPO1_HUMAN Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog) XPO1 CRM1 Homo sapiens (Human) mRNA export from nucleus [GO:0006406]; nucleocytoplasmic transport [GO:0006913]; protein export from nucleus [GO:0006611]; protein localization to nucleus [GO:0034504]; regulation of centrosome duplication [GO:0010824]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; regulation of protein export from nucleus [GO:0046825]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; ribosomal subunit export from nucleus [GO:0000054]; ribosome biogenesis [GO:0042254] annulate lamellae [GO:0005642]; Cajal body [GO:0015030]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; kinetochore [GO:0000776]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904] nuclear export signal receptor activity [GO:0005049]; RNA binding [GO:0003723]; small GTPase binding [GO:0031267] 0.89048 -0.46746 DLLGLCEQKR 0 0 0 0 0 0 0 0 0 0 9.18708 0 0 0 0 0 0 0 0 0 0 0 10.149 0 0 0 0 O14981 BTAF1_HUMAN TATA-binding protein-associated factor 172 (EC 3.6.4.-) (ATP-dependent helicase BTAF1) (B-TFIID transcription factor-associated 170 kDa subunit) (TAF(II)170) (TBP-associated factor 172) (TAF-172) BTAF1 TAF172 Homo sapiens (Human) negative regulation of chromatin binding [GO:0035562]; negative regulation of DNA-templated transcription [GO:0045892] intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654] "ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent activity, acting on DNA [GO:0008094]; ATP-dependent chromatin remodeler activity [GO:0140658]; DNA binding [GO:0003677]; helicase activity [GO:0004386]; TBP-class protein binding [GO:0017025]; transcription coregulator activity [GO:0003712]" 0.8487 0.15704 FGDFVSDEVVAPVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.54543 0 0 0 13.3975 0 O14994 SYN3_HUMAN Synapsin-3 (Synapsin III) SYN3 Homo sapiens (Human) "neurotransmitter secretion [GO:0007269]; regulation of synaptic transmission, GABAergic [GO:0032228]; synaptic vesicle clustering [GO:0097091]" extrinsic component of synaptic vesicle membrane [GO:0098850]; glutamatergic synapse [GO:0098978]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672] ATP binding [GO:0005524] 0.62387 0.41499 IFHSLGPEK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4824 0 0 0 0 0 0 9.24039 0 0 0 0 0 0 O15013 ARHGA_HUMAN Rho guanine nucleotide exchange factor 10 ARHGEF10 KIAA0294 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; activation of GTPase activity [GO:0090630]; centrosome duplication [GO:0051298]; mitotic spindle assembly [GO:0090307]; myelination in peripheral nervous system [GO:0022011]; positive regulation of stress fiber assembly [GO:0051496]; regulation of small GTPase mediated signal transduction [GO:0051056] centrosome [GO:0005813]; cytosol [GO:0005829] guanyl-nucleotide exchange factor activity [GO:0005085]; kinesin binding [GO:0019894] 0.96428 -2.3834 AINERYLNK 0 0 0 0 0 0 0 11.8182 0 0 0 0 0 0 0 0 10.671 10.6544 0 9.82653 0 11.2624 0 0 0 0 0 O15014 ZN609_HUMAN Zinc finger protein 609 ZNF609 KIAA0295 Homo sapiens (Human) muscle organ development [GO:0007517]; positive regulation of neuron migration [GO:2001224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of myoblast proliferation [GO:2000291]; regulation of transcription by RNA polymerase II [GO:0006357] nucleoplasm [GO:0005654]; nucleus [GO:0005634] metal ion binding [GO:0046872]; promoter-specific chromatin binding [GO:1990841] 0.96263 -2.0836 TKRDEEPESIEGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7728 O15015 ZN646_HUMAN Zinc finger protein 646 ZNF646 KIAA0296 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96398 -2.2553 AGGASGGR 9.048 0 0 0 0 0 0 11.0741 0 0 0 9.25578 0 0 8.89712 0 0 8.62344 0 0 0 0 0 0 0 0 0 O15018 PDZD2_HUMAN PDZ domain-containing protein 2 (Activated in prostate cancer protein) (PDZ domain-containing protein 3) [Cleaved into: Processed PDZ domain-containing protein 2] PDZD2 AIPC KIAA0300 PDZK3 Homo sapiens (Human) cell adhesion [GO:0007155] cell-cell junction [GO:0005911]; centriolar satellite [GO:0034451]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; plasma membrane [GO:0005886] 0.96941 -6.1764 AGGTDHR 0 0 0 0 0 0 9.665 0 0 9.65032 0 9.61784 0 0 11.943 0 0 0 0 9.44087 0 0 0 0 0 0 0 O15020 SPTN2_HUMAN "Spectrin beta chain, non-erythrocytic 2 (Beta-III spectrin) (Spinocerebellar ataxia 5 protein)" SPTBN2 KIAA0302 SCA5 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament capping [GO:0051693]; adult behavior [GO:0030534]; cerebellar Purkinje cell layer morphogenesis [GO:0021692]; multicellular organism growth [GO:0035264]; regulation of postsynaptic specialization assembly [GO:0099150]; synapse assembly [GO:0007416]; vesicle-mediated transport [GO:0016192] apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell projection [GO:0042995]; cortical actin cytoskeleton [GO:0030864]; cytosol [GO:0005829]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; parallel fiber to Purkinje cell synapse [GO:0098688]; paranodal junction [GO:0033010]; plasma membrane [GO:0005886]; postsynaptic spectrin-associated cytoskeleton [GO:0099189]; presynapse [GO:0098793]; spectrin [GO:0008091] actin binding [GO:0003779]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; phospholipid binding [GO:0005543]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of postsynapse [GO:0099186]; structural constituent of synapse [GO:0098918] 0.96901 -6.5486 DALLLWCQMK 0 9.89295 0 0 0 0 11.3913 0 0 0 12.5915 10.9287 9.45621 0 9.9969 0 0 9.51118 10.9204 0 0 0 0 0 9.173 0 0 O15021 MAST4_HUMAN Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1) MAST4 KIAA0303 Homo sapiens (Human) cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; proteolysis [GO:0006508] cytoplasm [GO:0005737] ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96954 -6.5017 AWAPGGK 0 9.24907 0 0 0 0 0 9.34944 9.45738 12.658 12.7518 0 9.8544 10.5144 0 10.8415 0 0 9.00647 0 0 0 9.6862 0 0 0 0 O15027 SC16A_HUMAN Protein transport protein Sec16A (SEC16 homolog A) (p250) SEC16A KIAA0310 SEC16 SEC16L Homo sapiens (Human) autophagy [GO:0006914]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; Golgi to plasma membrane transport [GO:0006893]; protein exit from endoplasmic reticulum [GO:0032527]; protein localization to endoplasmic reticulum exit site [GO:0070973]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; response to endoplasmic reticulum stress [GO:0034976]; substantia nigra development [GO:0021762] cytosol [GO:0005829]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; organelle membrane [GO:0031090]; perinuclear region of cytoplasm [GO:0048471] 0.88677 -0.34791 FGPGGQLIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1457 0 0 O15031 PLXB2_HUMAN Plexin-B2 (MM1) PLXNB2 KIAA0315 Homo sapiens (Human) brain development [GO:0007420]; excitatory synapse assembly [GO:1904861]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell adhesion [GO:0007162]; neural tube closure [GO:0001843]; neuroblast proliferation [GO:0007405]; positive regulation of axonogenesis [GO:0050772]; positive regulation of neuron projection development [GO:0010976]; positive regulation of translation [GO:0045727]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of neuron migration [GO:2001222]; regulation of protein phosphorylation [GO:0001932]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287] cell surface [GO:0009986]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; semaphorin receptor complex [GO:0002116] semaphorin receptor activity [GO:0017154] 0.96926 -4.4297 CTRKAECPR 0 9.9857 9.9349 0 0 0 10.1079 9.87672 0 9.45492 0 0 0 0 0 10.0562 0 8.75566 0 0 0 0 0 0 0 0 0 O15033 AREL1_HUMAN Apoptosis-resistant E3 ubiquitin protein ligase 1 (EC 2.3.2.26) (Apoptosis-resistant HECT-type E3 ubiquitin transferase 1) AREL1 KIAA0317 Homo sapiens (Human) apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; protein K11-linked ubiquitination [GO:0070979]; protein K33-linked ubiquitination [GO:1990390]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of inflammatory response [GO:0050727]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737]; cytosol [GO:0005829] ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.96219 -2.5472 ELRQVHMK 8.84618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0312 0 0 0 0 O15034 RIMB2_HUMAN RIMS-binding protein 2 (RIM-BP2) RIMBP2 KIAA0318 RBP2 Homo sapiens (Human) neuromuscular synaptic transmission [GO:0007274] plasma membrane [GO:0005886]; synapse [GO:0045202] 0.96952 -3.5415 DADGFYRGETCAR 10.1344 0 0 0 0 0 9.75273 0 9.49845 12.7069 13.0187 13.0277 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15037 KHNYN_HUMAN Protein KHNYN (KH and NYN domain-containing protein) KHNYN KIAA0323 Homo sapiens (Human) "RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]" cytoplasmic ribonucleoprotein granule [GO:0036464]; nucleus [GO:0005634] mRNA binding [GO:0003729]; RNA endonuclease activity [GO:0004521] 0.8819 0.010041 ESLDTGSMGPGDCR 0 0 0 0 0 0 9.3456 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15040 TCPR2_HUMAN Tectonin beta-propeller repeat-containing protein 2 (WD repeat-containing protein KIAA0329/KIAA0297) TECPR2 KIAA0297 KIAA0329 Homo sapiens (Human) autophagy [GO:0006914]; protein exit from endoplasmic reticulum [GO:0032527] cytoplasm [GO:0005737] 0.91988 -0.90519 AFACGKVTIKGK 0 0 0 0 0 0 8.50387 8.58661 0 0 0 0 0 0 10.4886 0 0 0 0 0 0 0 0 0 0 0 0 O15041 SEM3E_HUMAN Semaphorin-3E SEMA3E KIAA0331 SEMAH Homo sapiens (Human) branching involved in blood vessel morphogenesis [GO:0001569]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; negative chemotaxis [GO:0050919]; negative regulation of angiogenesis [GO:0016525]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of neuron apoptotic process [GO:0043524]; neural crest cell migration [GO:0001755]; positive regulation of cell migration [GO:0030335]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of cell shape [GO:0008360]; semaphorin-plexin signaling pathway [GO:0071526]; sprouting angiogenesis [GO:0002040]; synapse organization [GO:0050808] extracellular region [GO:0005576]; extracellular space [GO:0005615] chemorepellent activity [GO:0045499]; receptor ligand activity [GO:0048018]; semaphorin receptor binding [GO:0030215] 0.92379 -1.0354 ETRKEEVK 0 0 0 0 0 0 0 0 0 0 11.2786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15042 SR140_HUMAN U2 snRNP-associated SURP motif-containing protein (140 kDa Ser/Arg-rich domain protein) (U2-associated protein SR140) U2SURP KIAA0332 SR140 Homo sapiens (Human) RNA processing [GO:0006396] nucleoplasm [GO:0005654]; nucleus [GO:0005634] RNA binding [GO:0003723] 0.96777 -3.7375 EGPMFEAMIMNR 0 0 9.85851 0 0 9.10991 9.02217 0 9.59639 0 0 0 0 0 0 9.77355 0 0 0 0 0 0 0 0 0 0 0 O15047 SET1A_HUMAN Histone-lysine N-methyltransferase SETD1A (EC 2.1.1.364) (Lysine N-methyltransferase 2F) (SET domain-containing protein 1A) (hSET1A) (Set1/Ash2 histone methyltransferase complex subunit SET1) SETD1A KIAA0339 KMT2F SET1 SET1A Homo sapiens (Human) brain development [GO:0007420]; DNA damage response [GO:0006974]; histone H3-K4 methylation [GO:0051568]; regulation of chromatin organization [GO:1902275]; regulation of hematopoietic stem cell differentiation [GO:1902036] chromatin [GO:0000785]; histone methyltransferase complex [GO:0035097]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188] beta-catenin binding [GO:0008013]; histone H3K4 methyltransferase activity [GO:0042800]; histone H3K4 monomethyltransferase activity [GO:0140945]; histone H3K4 trimethyltransferase activity [GO:0140999]; RNA binding [GO:0003723]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629] 0.92375 -1.0497 QPIGVDEEITYDYK 0 0 0 0 0 0 0 0 0 0 12.4487 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15049 N4BP3_HUMAN NEDD4-binding protein 3 (N4BP3) N4BP3 KIAA0341 Homo sapiens (Human) innate immune response [GO:0045087]; nervous system development [GO:0007399] axon [GO:0030424]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425] ubiquitin-protein transferase activator activity [GO:0097027] 0.91779 -0.85758 SPGTGPSPFSSSLGHLNHLGGSLDR 10.351 9.11249 10.0407 0 9.84043 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15050 TRNK1_HUMAN TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog) TRANK1 KIAA0342 LBA1 Homo sapiens (Human) 0.96847 -8.781 DARDWLMKTETR 11.5047 0 0 0 0 9.18743 0 0 10.6557 0 0 10.6991 10.7105 11.1885 11.1119 0 11.1447 11.0008 9.61134 0 10.5054 9.85119 0 10.1311 0 0 10.9593 O15054 KDM6B_HUMAN Lysine-specific demethylase 6B (EC 1.14.11.68) (JmjC domain-containing protein 3) (Jumonji domain-containing protein 3) (Lysine demethylase 6B) ([histone H3]-trimethyl-L-lysine(27) demethylase 6B) KDM6B JMJD3 KIAA0346 Homo sapiens (Human) cardiac muscle cell differentiation [GO:0055007]; cell fate commitment [GO:0045165]; cellular response to hydrogen peroxide [GO:0070301]; chromatin remodeling [GO:0006338]; endothelial cell differentiation [GO:0045446]; histone H3-K27 demethylation [GO:0071557]; inflammatory response [GO:0006954]; mesodermal cell differentiation [GO:0048333]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468] MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] beta-catenin binding [GO:0008013]; chromatin DNA binding [GO:0031490]; histone demethylase activity [GO:0032452]; histone H3K27me2/H3K27me3 demethylase activity [GO:0071558]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96932 -3.2095 EEAPGPPGVSR 0 0 0 0 0 0 10.679 0 0 0 9.15687 9.56727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15055 PER2_HUMAN Period circadian protein homolog 2 (hPER2) (Circadian clock protein PERIOD 2) PER2 KIAA0347 Homo sapiens (Human) chromatin remodeling [GO:0006338]; circadian regulation of gene expression [GO:0032922]; circadian regulation of translation [GO:0097167]; circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; fatty acid metabolic process [GO:0006631]; gluconeogenesis [GO:0006094]; glycogen biosynthetic process [GO:0005978]; lactate biosynthetic process [GO:0019249]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of fat cell proliferation [GO:0070345]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of cell cycle [GO:0051726]; regulation of circadian rhythm [GO:0042752]; regulation of glutamate uptake involved in transmission of nerve impulse [GO:0051946]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of vasoconstriction [GO:0019229]; response to ischemia [GO:0002931]; white fat cell differentiation [GO:0050872] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] transcription cis-regulatory region binding [GO:0000976]; transcription coactivator activity [GO:0003713]; transcription corepressor binding [GO:0001222] 0.63278 0.39957 EVLAAHTQK 9.41519 9.34574 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15056 SYNJ2_HUMAN "Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2)" SYNJ2 KIAA0348 Homo sapiens (Human) brain development [GO:0007420]; membrane organization [GO:0061024]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; synaptic vesicle endocytosis [GO:0048488] cell projection [GO:0042995]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynapse [GO:0098793] "phosphatidylinositol phosphate 4-phosphatase activity [GO:0034596]; phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity [GO:0052629]; phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity [GO:0043813]; phosphatidylinositol-3-phosphate phosphatase activity [GO:0004438]; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity [GO:0004439]; RNA binding [GO:0003723]" 0.90765 -0.737 GENVSPRFQK 0 0 0 0 0 0 0 0 0 0 9.86042 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15061 SYNEM_HUMAN Synemin (Desmuslin) SYNM DMN KIAA0353 SYN Homo sapiens (Human) fast-twitch skeletal muscle fiber contraction [GO:0031443]; intermediate filament cytoskeleton organization [GO:0045104] adherens junction [GO:0005912]; costamere [GO:0043034]; intermediate filament [GO:0005882]; intermediate filament cytoskeleton [GO:0045111]; neurofilament cytoskeleton [GO:0060053]; sarcolemma [GO:0042383] intermediate filament binding [GO:0019215]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; vinculin binding [GO:0017166] 0.96937 -4.7971 ATLTLAMADWLRDYQDLLQVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4415 0 0 9.6143 9.71965 0 9.9067 0 0 O15062 ZBTB5_HUMAN Zinc finger and BTB domain-containing protein 5 ZBTB5 KIAA0354 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.9351 -1.291 KQSAEERAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3136 0 0 O15063 GRRE1_HUMAN Granule associated Rac and RHOG effector protein 1 (GARRE1) GARRE1 KIAA0355 Homo sapiens (Human) Rac protein signal transduction [GO:0016601] cytosol [GO:0005829]; P-body [GO:0000932] CCR4-NOT complex binding [GO:1905762]; small GTPase binding [GO:0031267] 0.96452 -2.6927 LTSRFTK 0 0 0 0 0 0 0 0 8.74514 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15066 KIF3B_HUMAN "Kinesin-like protein KIF3B (HH0048) (Microtubule plus end-directed kinesin motor 3B) [Cleaved into: Kinesin-like protein KIF3B, N-terminally processed]" KIF3B KIAA0359 Homo sapiens (Human) anterograde axonal transport [GO:0008089]; anterograde dendritic transport of neurotransmitter receptor complex [GO:0098971]; cilium assembly [GO:0060271]; determination of left/right symmetry [GO:0007368]; intraciliary transport [GO:0042073]; microtubule-based movement [GO:0007018]; mitotic centrosome separation [GO:0007100]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; opsin transport [GO:0036372]; plus-end-directed vesicle transport along microtubule [GO:0072383]; positive regulation of cytokinesis [GO:0032467]; vesicle-mediated transport [GO:0016192] axon cytoplasm [GO:1904115]; centrosome [GO:0005813]; ciliary tip [GO:0097542]; cilium [GO:0005929]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; kinesin complex [GO:0005871]; kinesin II complex [GO:0016939]; membrane [GO:0016020]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; plus-end kinesin complex [GO:0005873]; spindle [GO:0005819] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; intraciliary transport particle B binding [GO:0120170]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777]; plus-end-directed microtubule motor activity [GO:0008574]; small GTPase binding [GO:0031267] 0.96988 -4.0313 AASYDKVVDVDVK 0 0 0 10.1825 0 10.0083 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.10497 0 0 0 0 O15067 PUR4_HUMAN Phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribonucleotide amidotransferase) (FGAR amidotransferase) (FGAR-AT) (Formylglycinamide ribotide amidotransferase) (Phosphoribosylformylglycineamide amidotransferase) PFAS KIAA0361 Homo sapiens (Human) 'de novo' AMP biosynthetic process [GO:0044208]; 'de novo' IMP biosynthetic process [GO:0006189]; 'de novo' XMP biosynthetic process [GO:0097294]; anterior head development [GO:0097065]; glutamine metabolic process [GO:0006541]; GMP biosynthetic process [GO:0006177]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to xenobiotic stimulus [GO:0009410] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylformylglycinamidine synthase activity [GO:0004642] 0.86942 0.046791 HLAVMPHPER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0557 0 0 O15068 MCF2L_HUMAN Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2-transforming sequence-like protein) MCF2L KIAA0362 OST Homo sapiens (Human) intracellular signal transduction [GO:0035556]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of small GTPase mediated signal transduction [GO:0051056] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; extracellular space [GO:0005615]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; extrinsic component of membrane [GO:0019898]; plasma membrane [GO:0005886] guanyl-nucleotide exchange factor activity [GO:0005085]; phosphatidylinositol binding [GO:0035091] 0.8971 -0.53146 DLASFEEK 0 0 0 0 0 0 0 0 11.0126 10.9177 11.129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15069 NACAD_HUMAN NAC-alpha domain-containing protein 1 NACAD KIAA0363 Homo sapiens (Human) protein targeting to membrane [GO:0006612] cytoplasm [GO:0005737]; nascent polypeptide-associated complex [GO:0005854]; nucleus [GO:0005634] unfolded protein binding [GO:0051082] 0.77179 0.27487 DNHSDIVNAIMELTM 0 0 0 0 0 0 0 0 0 0 0 9.13062 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15072 ATS3_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 3 (ADAM-TS 3) (ADAM-TS3) (ADAMTS-3) (EC 3.4.24.-) (Procollagen II N-proteinase) (PC II-NP) (Procollagen II amino propeptide-processing enzyme) ADAMTS3 KIAA0366 Homo sapiens (Human) collagen biosynthetic process [GO:0032964]; collagen catabolic process [GO:0030574]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; in utero embryonic development [GO:0001701]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; protein processing [GO:0016485]; supramolecular fiber organization [GO:0097435]; vascular endothelial growth factor production [GO:0010573] extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] endopeptidase activity [GO:0004175]; heparin binding [GO:0008201]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270] 0.95103 -1.3838 DPYSICVR 0 0 0 0 0 0 0 0 0 0 8.28179 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15078 CE290_HUMAN Centrosomal protein of 290 kDa (Cep290) (Bardet-Biedl syndrome 14 protein) (Cancer/testis antigen 87) (CT87) (Nephrocystin-6) (Tumor antigen se2-2) CEP290 BBS14 KIAA0373 NPHP6 Homo sapiens (Human) camera-type eye development [GO:0043010]; cilium assembly [GO:0060271]; eye photoreceptor cell development [GO:0042462]; hindbrain development [GO:0030902]; kidney development [GO:0001822]; otic vesicle formation [GO:0030916]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of intracellular protein transport [GO:0090316]; pronephros development [GO:0048793]; protein transport [GO:0015031]; regulation of establishment of protein localization [GO:0070201] centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary transition zone [GO:0035869]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; MKS complex [GO:0036038]; nucleus [GO:0005634]; photoreceptor connecting cilium [GO:0032391]; protein-containing complex [GO:0032991]; specific granule lumen [GO:0035580] identical protein binding [GO:0042802] 0.95732 -1.6537 DKELVEALKR 0 10.0629 0 0 0 0 0 0 0 0 10.8874 11.2683 0 0 0 0 0 11.377 0 0 0 0 10.0996 0 10.3884 9.50736 0 O15083 ERC2_HUMAN ERC protein 2 ERC2 KIAA0378 Homo sapiens (Human) maintenance of presynaptic active zone structure [GO:0048790]; neuromuscular synaptic transmission [GO:0007274]; regulation of calcium-dependent activation of synaptic vesicle fusion [GO:0150037]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; regulation of synaptic plasticity [GO:0048167]; synaptic vesicle priming [GO:0016082] cytoskeleton of presynaptic active zone [GO:0048788]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; presynaptic active zone [GO:0048786]; presynaptic membrane [GO:0042734] structural constituent of presynaptic active zone [GO:0098882] 0.8356 0.18792 EAHLANLR 0 9.99223 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.70641 0 0 0 O15084 ANR28_HUMAN Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A (PP6-ARS-A) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A) (Ankyrin repeat domain-containing protein 28) (Phosphatase interactor targeting protein hnRNP K) (PITK) ANKRD28 KIAA0379 Homo sapiens (Human) cytosol [GO:0005829]; nucleoplasm [GO:0005654] 0.43515 0.65516 AVKCAEALVPLLSNVNVSDRAGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.9714 0 O15085 ARHGB_HUMAN Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF) ARHGEF11 KIAA0380 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; establishment of cell polarity [GO:0030010]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cell growth [GO:0001558]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; striated muscle contraction [GO:0006941] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] G protein-coupled receptor binding [GO:0001664]; GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085] 0.96559 -2.72 EKDALEDK 0 0 0 0 0 0 0 0 0 0 9.76914 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15090 ZN536_HUMAN Zinc finger protein 536 ZNF536 KIAA0390 Homo sapiens (Human) negative regulation of neuron differentiation [GO:0045665]; negative regulation of retinoic acid receptor signaling pathway [GO:0048387]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; retinoic acid-responsive element binding [GO:0044323]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.92026 -0.9257 DSFEHCCQICGR 0 0 0 0 0 0 0 0 0 0 10.0201 0 0 0 0 0 0 0 10.8271 0 0 9.32841 10.2141 0 0 0 11.6213 O15091 MRPP3_HUMAN Mitochondrial ribonuclease P catalytic subunit (EC 3.1.26.5) (Mitochondrial ribonuclease P protein 3) (Mitochondrial RNase P protein 3) (Protein only RNase P catalytic subunit) PRORP KIAA0391 MRPP3 Homo sapiens (Human) mitochondrial tRNA 5'-end processing [GO:0097745]; tRNA 5'-leader removal [GO:0001682] mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrial ribonuclease P complex [GO:0030678]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] metal ion binding [GO:0046872]; ribonuclease P activity [GO:0004526] 0.95407 -1.5177 AFFDFGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.34223 8.4028 0 0 0 11.2644 0 0 O15105 SMAD7_HUMAN Mothers against decapentaplegic homolog 7 (MAD homolog 7) (Mothers against DPP homolog 7) (Mothers against decapentaplegic homolog 8) (MAD homolog 8) (Mothers against DPP homolog 8) (SMAD family member 7) (SMAD 7) (Smad7) (hSMAD7) SMAD7 MADH7 MADH8 Homo sapiens (Human) adherens junction assembly [GO:0034333]; anatomical structure morphogenesis [GO:0009653]; artery morphogenesis [GO:0048844]; cell differentiation [GO:0030154]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to transforming growth factor beta stimulus [GO:0071560]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell migration [GO:0030336]; negative regulation of chondrocyte proliferation [GO:1902731]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ossification [GO:0030279]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of T cell cytokine production [GO:0002725]; negative regulation of T-helper 17 cell differentiation [GO:2000320]; negative regulation of T-helper 17 type immune response [GO:2000317]; negative regulation of transcription by competitive promoter binding [GO:0010944]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of chondrocyte hypertrophy [GO:1903043]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; protein stabilization [GO:0050821]; protein-containing complex localization [GO:0031503]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of cardiac muscle contraction [GO:0055117]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; regulation of ventricular cardiac muscle cell membrane depolarization [GO:0060373]; response to laminar fluid shear stress [GO:0034616]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular septum morphogenesis [GO:0060412] centrosome [GO:0005813]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; heteromeric SMAD protein complex [GO:0071144]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] activin binding [GO:0048185]; beta-catenin binding [GO:0008013]; collagen binding [GO:0005518]; I-SMAD binding [GO:0070411]; metal ion binding [GO:0046872]; transcription regulator inhibitor activity [GO:0140416]; type I transforming growth factor beta receptor binding [GO:0034713]; ubiquitin protein ligase binding [GO:0031625] 0.95531 -1.553 AGCCLGKAVRGAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1728 0 0 0 0 0 0 O15111 IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK-1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16) CHUK IKKA TCF16 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to virus [GO:0098586]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; I-kappaB phosphorylation [GO:0007252]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; NIK/NF-kappaB signaling [GO:0038061]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; response to virus [GO:0009615]; tumor necrosis factor-mediated signaling pathway [GO:0033209] CD40 receptor complex [GO:0035631]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IkappaB kinase complex [GO:0008385]; nucleoplasm [GO:0005654] ATP binding [GO:0005524]; IkappaB kinase activity [GO:0008384]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; scaffold protein binding [GO:0097110]; transferrin receptor binding [GO:1990459] 0.84915 0.15495 EIWHLLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.58496 0 0 0 0 0 0 0 0 O15117 FYB1_HUMAN FYN-binding protein 1 (Adhesion and degranulation promoting adaptor protein) (ADAP) (FYB-120/130) (p120/p130) (FYN-T-binding protein) (SLAP-130) (SLP-76-associated phosphoprotein) FYB1 FYB SLAP130 Homo sapiens (Human) immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; protein localization to plasma membrane [GO:0072659]; T cell receptor signaling pathway [GO:0050852] actin cytoskeleton [GO:0015629]; anchoring junction [GO:0070161]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] lipid binding [GO:0008289]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102] 0.96801 -3.7284 EEKDFRK 10.2908 0 9.96212 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.44377 0 0 0 0 O15118 NPC1_HUMAN NPC intracellular cholesterol transporter 1 (Niemann-Pick C1 protein) NPC1 Homo sapiens (Human) adult walking behavior [GO:0007628]; autophagy [GO:0006914]; bile acid metabolic process [GO:0008206]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to steroid hormone stimulus [GO:0071383]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol storage [GO:0010878]; cholesterol transport [GO:0030301]; cyclodextrin metabolic process [GO:2000900]; endocytosis [GO:0006897]; establishment of protein localization to membrane [GO:0090150]; gene expression [GO:0010467]; intestinal cholesterol absorption [GO:0030299]; intracellular cholesterol transport [GO:0032367]; liver development [GO:0001889]; lysosomal transport [GO:0007041]; macroautophagy [GO:0016236]; membrane raft organization [GO:0031579]; negative regulation of cell death [GO:0060548]; negative regulation of macroautophagy [GO:0016242]; negative regulation of TORC1 signaling [GO:1904262]; neurogenesis [GO:0022008]; programmed cell death [GO:0012501]; protein glycosylation [GO:0006486]; response to cadmium ion [GO:0046686]; response to xenobiotic stimulus [GO:0009410]; viral entry into host cell [GO:0046718] endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; nuclear envelope [GO:0005635]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] cholesterol binding [GO:0015485]; signaling receptor activity [GO:0038023]; sterol transporter activity [GO:0015248]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618] 0.92136 -1.0938 EFINFVKNYK 0 0 0 0 0 0 0 8.59656 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15123 ANGP2_HUMAN Angiopoietin-2 (ANG-2) ANGPT2 Homo sapiens (Human) angiogenesis [GO:0001525]; animal organ regeneration [GO:0031100]; cellular response to growth factor stimulus [GO:0071363]; gene expression [GO:0010467]; germ cell development [GO:0007281]; glomerulus vasculature development [GO:0072012]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of positive chemotaxis [GO:0050928]; positive regulation of angiogenesis [GO:0045766]; response to activity [GO:0014823]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to radiation [GO:0009314]; signal transduction [GO:0007165]; Tie signaling pathway [GO:0048014] cell projection [GO:0042995]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886] metal ion binding [GO:0046872]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102] 0.96985 -4.0773 GSGYSLK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.69302 0 0 0 0 9.03196 0 0 0 0 0 0 0 0 O15126 SCAM1_HUMAN Secretory carrier-associated membrane protein 1 (Secretory carrier membrane protein 1) SCAMP1 SCAMP Homo sapiens (Human) endocytosis [GO:0006897]; establishment of localization in cell [GO:0051649]; exocytosis [GO:0006887]; post-Golgi vesicle-mediated transport [GO:0006892]; protein transport [GO:0015031] clathrin-coated vesicle [GO:0030136]; membrane [GO:0016020]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule membrane [GO:0035579]; synaptic vesicle membrane [GO:0030672]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588]; zymogen granule membrane [GO:0042589] protein domain specific binding [GO:0019904] 0.89897 -0.6009 EHALAQAELLK 0 11.375 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1012 O15144 ARPC2_HUMAN Actin-related protein 2/3 complex subunit 2 (Arp2/3 complex 34 kDa subunit) (p34-ARC) ARPC2 ARC34 PRO2446 Homo sapiens (Human) actin filament polymerization [GO:0030041]; actin polymerization-dependent cell motility [GO:0070358]; Arp2/3 complex-mediated actin nucleation [GO:0034314]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026] actin cytoskeleton [GO:0015629]; Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; lamellipodium [GO:0030027]; muscle cell projection membrane [GO:0036195]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861] actin binding [GO:0003779]; structural constituent of cytoskeleton [GO:0005200] 0.91982 -0.90625 AKTSDFLK 10.1579 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15145 ARPC3_HUMAN Actin-related protein 2/3 complex subunit 3 (Arp2/3 complex 21 kDa subunit) (p21-ARC) ARPC3 ARC21 Homo sapiens (Human) actin polymerization-dependent cell motility [GO:0070358]; Arp2/3 complex-mediated actin nucleation [GO:0034314]; regulation of actin filament polymerization [GO:0030833] actin cytoskeleton [GO:0015629]; Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; membrane [GO:0016020]; nucleus [GO:0005634]; site of double-strand break [GO:0035861] actin binding [GO:0003779]; structural constituent of cytoskeleton [GO:0005200] 0.96939 -4.1752 QETGLRLCEK 0 0 10.1344 0 0 0 0 9.56281 0 8.89285 9.54272 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15146 MUSK_HUMAN "Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase receptor) (MuSK) (Muscle-specific kinase receptor)" MUSK Homo sapiens (Human) cell differentiation [GO:0030154]; memory [GO:0007613]; neuromuscular junction development [GO:0007528]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein geranylgeranylation [GO:2000541]; positive regulation of protein phosphorylation [GO:0001934]; protein autophosphorylation [GO:0046777]; regulation of synaptic assembly at neuromuscular junction [GO:0008582]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] neuromuscular junction [GO:0031594]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; receptor complex [GO:0043235] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; Wnt-protein binding [GO:0017147] 0.96962 -4.0181 ELFCAKEWLVMEEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.9753 0 0 0 11.9858 0 10.7575 O15151 MDM4_HUMAN Protein Mdm4 (Double minute 4 protein) (Mdm2-like p53-binding protein) (Protein Mdmx) (p53-binding protein Mdm4) MDM4 MDMX Homo sapiens (Human) "atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; endocardial cushion morphogenesis [GO:0003203]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; regulation of cell cycle [GO:0051726]; ventricular septum development [GO:0003281]" nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription repressor complex [GO:0017053] enzyme binding [GO:0019899]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.90515 -0.72152 FNSPSKRYCFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1405 0 0 0 0 0 0 0 0 0 0 0 O15155 BET1_HUMAN BET1 homolog (hBET1) (Golgi vesicular membrane-trafficking protein p18) BET1 Homo sapiens (Human) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein transport [GO:0015031]; vesicle fusion with Golgi apparatus [GO:0048280] endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; SNARE complex [GO:0031201]; transport vesicle [GO:0030133] SNAP receptor activity [GO:0005484] 0.93217 -1.2681 ILSRGSQTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6282 0 0 0 0 0 0 0 0 0 0 0 O15156 ZBT7B_HUMAN Zinc finger and BTB domain-containing protein 7B (Krueppel-related zinc finger protein cKrox) (hcKrox) (T-helper-inducing POZ/Krueppel-like factor) (Zinc finger and BTB domain-containing protein 15) (Zinc finger protein 67 homolog) (Zfp-67) (Zinc finger protein 857B) (Zinc finger protein Th-POK) ZBTB7B ZBTB15 ZFP67 ZNF857B Homo sapiens (Human) "adaptive thermogenesis [GO:1990845]; ectoderm development [GO:0007398]; lactation [GO:0007595]; negative regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043377]; negative regulation of gene expression [GO:0010629]; negative regulation of NK T cell proliferation [GO:0051141]; negative regulation of T-helper 17 cell differentiation [GO:2000320]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NK T cell differentiation [GO:0001865]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043372]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of SREBP signaling pathway [GO:2000640]; regulation of transcription by RNA polymerase II [GO:0006357]; response to insulin [GO:0032868]; transcription by RNA polymerase II [GO:0006366]" nucleoplasm [GO:0005654] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity [GO:0001217]; histone deacetylase binding [GO:0042826]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.88332 -0.29928 TQGLEYRTHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.258 0 0 O15160 RPAC1_HUMAN DNA-directed RNA polymerases I and III subunit RPAC1 (DNA-directed RNA polymerase I subunit C) (RNA polymerases I and III subunit AC1) (AC40) (DNA-directed RNA polymerases I and III 40 kDa polypeptide) (RPA40) (RPA39) (RPC40) POLR1C POLR1E Homo sapiens (Human) transcription by RNA polymerase I [GO:0006360] cytosol [GO:0005829]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; RNA polymerase I complex [GO:0005736]; RNA polymerase III complex [GO:0005666] DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; protein dimerization activity [GO:0046983]; RNA polymerase I activity [GO:0001054]; RNA polymerase III activity [GO:0001056] 0.93349 -1.2818 CTRNPHAAKDSSDPNELYVNHK 0 10.0595 0 0 0 0 0 0 0 0 0 9.61254 9.48846 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15178 TBXT_HUMAN T-box transcription factor T (Brachyury protein) (Protein T) TBXT T Homo sapiens (Human) "anterior/posterior axis specification, embryo [GO:0008595]; cardiac muscle cell myoblast differentiation [GO:0060379]; cell fate specification [GO:0001708]; heart morphogenesis [GO:0003007]; mesoderm development [GO:0007498]; mesoderm formation [GO:0001707]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; primitive streak formation [GO:0090009]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; somitogenesis [GO:0001756]" chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.56041 0.52578 ELTNEMIVTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.49707 0 0 0 0 10.1085 0 0 0 O15197 EPHB6_HUMAN Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6) EPHB6 Homo sapiens (Human) axon guidance [GO:0007411]; ephrin receptor signaling pathway [GO:0048013]; protein phosphorylation [GO:0006468] cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular region [GO:0005576]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; ephrin receptor activity [GO:0005003]; signaling receptor activity [GO:0038023]; transmembrane-ephrin receptor activity [GO:0005005] 0.80086 0.23947 TAAGHGPYGGK 0 8.90515 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15212 PFD6_HUMAN Prefoldin subunit 6 (Protein Ke2) PFDN6 HKE2 PFD6 Homo sapiens (Human) chaperone-mediated protein complex assembly [GO:0051131]; negative regulation of amyloid fibril formation [GO:1905907]; protein folding [GO:0006457]; protein stabilization [GO:0050821] cytoplasm [GO:0005737]; prefoldin complex [GO:0016272]; protein folding chaperone complex [GO:0101031]; RPAP3/R2TP/prefoldin-like complex [GO:1990062] amyloid-beta binding [GO:0001540]; protein-folding chaperone binding [GO:0051087]; unfolded protein binding [GO:0051082] 0.55872 0.54591 AGAPGKA 0 0 0 0 0 0 0 0 9.26148 9.16742 0 0 0 0 0 0 0 0 11.1775 11.0172 8.92899 9.07585 0 0 0 9.16305 0 O15213 WDR46_HUMAN WD repeat-containing protein 46 (WD repeat-containing protein BING4) WDR46 BING4 C6orf11 FP221 Homo sapiens (Human) "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosomal small subunit biogenesis [GO:0042274]" nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040] RNA binding [GO:0003723] 0.85541 0.10429 LEVAEAEEEETSIK 0 0 0 0 0 0 0 12.2226 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15226 NKRF_HUMAN NF-kappa-B-repressing factor (NFkB-repressing factor) (NRF) (Protein ITBA4) NKRF ITBA4 NRF Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of transcription by RNA polymerase II [GO:0045944] nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "ATPase activator activity [GO:0001671]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; RNA binding [GO:0003723]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.84439 0.15301 QIHQIAQK 0 0 0 0 0 0 0 0 9.52333 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15231 ZN185_HUMAN Zinc finger protein 185 (LIM domain protein ZNF185) (P1-A) ZNF185 Homo sapiens (Human) cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925] zinc ion binding [GO:0008270] 0.93184 -1.2729 LVAPDVEGMR 0 0 0 0 0 0 0 0 0 10.4243 0 0 0 0 0 0 0 0 0 0 0 0 0 9.33626 0 0 0 O15232 MATN3_HUMAN Matrilin-3 MATN3 Homo sapiens (Human) cartilage development [GO:0051216]; extracellular matrix organization [GO:0030198]; skeletal system development [GO:0001501] collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; matrilin complex [GO:0120216] calcium ion binding [GO:0005509]; extracellular matrix structural constituent [GO:0005201] 0.95376 -1.5243 KTCSALDR 0 8.44593 8.55539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15234 CASC3_HUMAN Protein CASC3 (Cancer susceptibility candidate gene 3 protein) (Metastatic lymph node gene 51 protein) (MLN 51) (Protein barentsz) (Btz) CASC3 MLN51 Homo sapiens (Human) "intracellular mRNA localization [GO:0008298]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000622]; regulation of translation [GO:0006417]" cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; dendrite [GO:0030425]; exon-exon junction complex [GO:0035145]; nuclear membrane [GO:0031965]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; U2-type catalytic step 1 spliceosome [GO:0071006] enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625] 0.95936 -1.9495 HQGLGGTLPPRTFINR 0 0 0 11.6259 0 0 0 0 0 0 0 0 0 10.7793 0 0 0 8.67642 0 9.65634 0 0 0 0 0 0 0 O15235 RT12_HUMAN "Small ribosomal subunit protein uS12m (28S ribosomal protein S12, mitochondrial) (MRP-S12) (S12mt) (MT-RPS12)" MRPS12 RPMS12 RPSM12 Homo sapiens (Human) mitochondrial translation [GO:0032543]; translation [GO:0006412] mitochondrial inner membrane [GO:0005743]; mitochondrial ribosome [GO:0005761]; mitochondrial small ribosomal subunit [GO:0005763]; ribosome [GO:0005840] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.96208 -2.5603 KPNSANR 0 0 0 0 0 0 0 0 0 0 0 12.2372 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15245 S22A1_HUMAN Solute carrier family 22 member 1 (Organic cation transporter 1) (hOCT1) SLC22A1 OCT1 Homo sapiens (Human) acetylcholine transport [GO:0015870]; acyl carnitine transmembrane transport [GO:1902616]; dopamine transport [GO:0015872]; dopamine uptake [GO:0090494]; epinephrine transport [GO:0048241]; establishment or maintenance of transmembrane electrochemical gradient [GO:0010248]; metanephric proximal tubule development [GO:0072237]; monoamine transport [GO:0015844]; neurotransmitter transport [GO:0006836]; norepinephrine transport [GO:0015874]; organic cation transport [GO:0015695]; prostaglandin transport [GO:0015732]; purine-containing compound transmembrane transport [GO:0072530]; putrescine transport [GO:0015847]; quaternary ammonium group transport [GO:0015697]; serotonin transport [GO:0006837]; serotonin uptake [GO:0051610]; spermidine transport [GO:0015848]; thiamine transmembrane transport [GO:0071934]; thiamine transport [GO:0015888]; toxin transport [GO:1901998]; transport across blood-brain barrier [GO:0150104]; xenobiotic metabolic process [GO:0006805]; xenobiotic transport [GO:0042908]; xenobiotic transport across blood-brain barrier [GO:1990962] apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; lateral plasma membrane [GO:0016328]; membrane [GO:0016020]; plasma membrane [GO:0005886]; presynapse [GO:0098793] (R)-carnitine transmembrane transporter activity [GO:1901235]; acetylcholine transmembrane transporter activity [GO:0005277]; dopamine:sodium symporter activity [GO:0005330]; identical protein binding [GO:0042802]; monoamine transmembrane transporter activity [GO:0008504]; neurotransmitter transmembrane transporter activity [GO:0005326]; norepinephrine:sodium symporter activity [GO:0005334]; organic anion transmembrane transporter activity [GO:0008514]; organic cation transmembrane transporter activity [GO:0015101]; prostaglandin transmembrane transporter activity [GO:0015132]; putrescine transmembrane transporter activity [GO:0015489]; pyrimidine nucleoside transmembrane transporter activity [GO:0015214]; quaternary ammonium group transmembrane transporter activity [GO:0015651]; secondary active organic cation transmembrane transporter activity [GO:0008513]; spermidine transmembrane transporter activity [GO:0015606]; thiamine transmembrane transporter activity [GO:0015234]; toxin transmembrane transporter activity [GO:0019534]; xenobiotic transmembrane transporter activity [GO:0042910] 0.56631 0.49984 GVALPETMK 0 9.44431 9.04191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15254 ACOX3_HUMAN Peroxisomal acyl-coenzyme A oxidase 3 (EC 1.3.3.6) (Branched-chain acyl-CoA oxidase) (BRCACox) (Pristanoyl-CoA oxidase) ACOX3 BRCOX PRCOX Homo sapiens (Human) fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088] cytosol [GO:0005829]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777] FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]; pristanoyl-CoA oxidase activity [GO:0016402] 0.89968 -0.69057 ETYQKLNQEK 0 0 0 0 0 0 0 11.6726 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15260 SURF4_HUMAN Surfeit locus protein 4 SURF4 SURF-4 Homo sapiens (Human) Golgi organization [GO:0007030]; lipid homeostasis [GO:0055088]; lipoprotein transport [GO:0042953]; positive regulation of organelle organization [GO:0010638]; regulation of lipid transport [GO:0032368] azurophil granule membrane [GO:0035577]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133] cargo receptor activity [GO:0038024] 0.22674 0.87689 SMFAGVPTMR 0 0 0 0 0 0 8.29453 0 0 9.63757 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15264 MK13_HUMAN Mitogen-activated protein kinase 13 (MAP kinase 13) (MAPK 13) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) (Stress-activated protein kinase 4) MAPK13 PRKM13 SAPK4 Homo sapiens (Human) cell cycle [GO:0007049]; cellular response to anisomycin [GO:0072740]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to sodium arsenite [GO:1903936]; cellular response to sorbitol [GO:0072709]; cellular response to UV [GO:0034644]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-6 production [GO:0032755]; response to osmotic stress [GO:0006970]; stress-activated MAPK cascade [GO:0051403] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] ATP binding [GO:0005524]; MAP kinase activity [GO:0004707]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.19345 0.9299 EIVNFSPIAR 0 0 0 0 10.4025 0 0 10.2447 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15265 ATX7_HUMAN Ataxin-7 (Spinocerebellar ataxia type 7 protein) ATXN7 SCA7 Homo sapiens (Human) histone H3 acetylation [GO:0043966]; microtubule cytoskeleton organization [GO:0000226]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; negative regulation of microtubule depolymerization [GO:0007026]; nucleus organization [GO:0006997]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA repair [GO:0006282]; regulation of RNA splicing [GO:0043484]; regulation of transcription by RNA polymerase II [GO:0006357]; visual perception [GO:0007601] cytosol [GO:0005829]; microtubule cytoskeleton [GO:0015630]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SAGA complex [GO:0000124]; transcription factor TFTC complex [GO:0033276] 0.88201 -0.094945 KPEDNSNNRK 0 0 0 0 0 0 11.4189 0 0 0 0 11.6404 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1461 O15266 SHOX_HUMAN Short stature homeobox protein (Pseudoautosomal homeobox-containing osteogenic protein) (Short stature homeobox-containing protein) SHOX PHOG Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501] chromatin [GO:0000785]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96772 -2.9595 LKEFGTAR 0 0 0 0 0 0 0 0 10.2666 0 0 0 9.19827 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15269 SPTC1_HUMAN Serine palmitoyltransferase 1 (EC 2.3.1.50) (Long chain base biosynthesis protein 1) (LCB 1) (Serine-palmitoyl-CoA transferase 1) (SPT 1) (SPT1) SPTLC1 LCB1 Homo sapiens (Human) ceramide biosynthetic process [GO:0046513]; positive regulation of lipophagy [GO:1904504]; regulation of fat cell apoptotic process [GO:1904649]; sphinganine biosynthetic process [GO:0046511]; sphingolipid biosynthetic process [GO:0030148]; sphingolipid metabolic process [GO:0006665]; sphingomyelin biosynthetic process [GO:0006686]; sphingosine biosynthetic process [GO:0046512] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; serine C-palmitoyltransferase complex [GO:0017059]; SPOTS complex [GO:0035339] pyridoxal phosphate binding [GO:0030170]; serine C-palmitoyltransferase activity [GO:0004758] 0.96958 -3.4555 AASTIKEVAQAVLL 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.93344 0 0 0 0 0 0 0 0 0 0 O15270 SPTC2_HUMAN Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Long chain base biosynthesis protein 2a) (LCB2a) (Serine-palmitoyl-CoA transferase 2) (SPT 2) SPTLC2 KIAA0526 LCB2 Homo sapiens (Human) adipose tissue development [GO:0060612]; ceramide biosynthetic process [GO:0046513]; positive regulation of lipophagy [GO:1904504]; sphinganine biosynthetic process [GO:0046511]; sphingolipid biosynthetic process [GO:0030148]; sphingomyelin biosynthetic process [GO:0006686]; sphingosine biosynthetic process [GO:0046512] endoplasmic reticulum membrane [GO:0005789]; serine C-palmitoyltransferase complex [GO:0017059] pyridoxal phosphate binding [GO:0030170]; serine C-palmitoyltransferase activity [GO:0004758] 0.55745 0.55209 HNNMQSLEK 0 0 0 0 0 0 0 0 0 0 0 11.489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15287 FANCG_HUMAN Fanconi anemia group G protein (Protein FACG) (DNA repair protein XRCC9) FANCG XRCC9 Homo sapiens (Human) DNA damage response [GO:0006974]; DNA repair [GO:0006281]; interstrand cross-link repair [GO:0036297]; mitochondrion organization [GO:0007005]; ovarian follicle development [GO:0001541]; protein monoubiquitination [GO:0006513]; response to radiation [GO:0009314]; spermatid development [GO:0007286] chromatin [GO:0000785]; cytosol [GO:0005829]; Fanconi anaemia nuclear complex [GO:0043240]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] damaged DNA binding [GO:0003684] 0.95422 -1.5258 TSSLLPKMSR 0 0 0 0 0 9.36069 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15294 OGT1_HUMAN UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT) OGT Homo sapiens (Human) apoptotic process [GO:0006915]; chromatin organization [GO:0006325]; circadian regulation of gene expression [GO:0032922]; hemopoiesis [GO:0030097]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; mitophagy [GO:0000423]; negative regulation of cell migration [GO:0030336]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of proteolysis [GO:0045862]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter by glucose [GO:0000432]; positive regulation of translation [GO:0045727]; protein O-linked glycosylation [GO:0006493]; protein processing [GO:0016485]; regulation of dosage compensation by inactivation of X chromosome [GO:1900095]; regulation of gluconeogenesis [GO:0006111]; regulation of glycolytic process [GO:0006110]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of necroptotic process [GO:0060544]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of Rac protein signal transduction [GO:0035020]; regulation of synapse assembly [GO:0051963]; regulation of transcription by RNA polymerase II [GO:0006357]; response to insulin [GO:0032868]; response to nutrient [GO:0007584]; signal transduction [GO:0007165] cell projection [GO:0042995]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; histone acetyltransferase complex [GO:0000123]; mitochondrial membrane [GO:0031966]; NSL complex [GO:0044545]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein N-acetylglucosaminyltransferase complex [GO:0017122]; protein-containing complex [GO:0032991]; Sin3 complex [GO:0016580] "acetylglucosaminyltransferase activity [GO:0008375]; chromatin DNA binding [GO:0031490]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; protein O-acetylglucosaminyltransferase activity [GO:0097363]; transcription regulator activator activity [GO:0140537]; translation regulator activity [GO:0045182]" 0.86494 0.085422 IDPSTLQMWANILK 0 0 0 0 0 0 0 0 0 0 0 10.8829 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15296 LX15B_HUMAN Polyunsaturated fatty acid lipoxygenase ALOX15B (15-lipoxygenase 2) (15-LOX-2) (Arachidonate 15-lipoxygenase B) (15-LOX-B) (EC 1.13.11.33) (Arachidonate 15-lipoxygenase type II) (Linoleate 13-lipoxygenase 15-LOb) (EC 1.13.11.-) ALOX15B Homo sapiens (Human) apoptotic process [GO:0006915]; arachidonic acid metabolic process [GO:0019369]; cannabinoid biosynthetic process [GO:1901696]; endocannabinoid signaling pathway [GO:0071926]; hepoxilin biosynthetic process [GO:0051122]; linoleic acid metabolic process [GO:0043651]; lipid metabolic process [GO:0006629]; lipid oxidation [GO:0034440]; lipoxin A4 biosynthetic process [GO:2001303]; lipoxygenase pathway [GO:0019372]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of growth [GO:0045926]; phospholipid metabolic process [GO:0006644]; positive regulation of chemokine production [GO:0032722]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360]; prostate gland development [GO:0030850]; regulation of epithelial cell differentiation [GO:0030856] adherens junction [GO:0005912]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886] arachidonate 15-lipoxygenase activity [GO:0050473]; arachidonate 8(S)-lipoxygenase activity [GO:0036403]; calcium ion binding [GO:0005509]; iron ion binding [GO:0005506]; linoleate 13S-lipoxygenase activity [GO:0016165]; linoleate 9S-lipoxygenase activity [GO:1990136]; lipid binding [GO:0008289] 0.014218 1.6834 ELLIVPGQVVDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.86412 0 0 9.76593 9.77426 9.82698 O15297 PPM1D_HUMAN Protein phosphatase 1D (EC 3.1.3.16) (Protein phosphatase 2C isoform delta) (PP2C-delta) (Protein phosphatase magnesium-dependent 1 delta) (p53-induced protein phosphatase 1) PPM1D WIP1 Homo sapiens (Human) "cellular response to starvation [GO:0009267]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA methylation [GO:0006306]; G2/M transition of mitotic cell cycle [GO:0000086]; heterochromatin formation [GO:0031507]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression, epigenetic [GO:0045814]; peptidyl-threonine dephosphorylation [GO:0035970]; protein dephosphorylation [GO:0006470]; regulation of transcription initiation by RNA polymerase II [GO:0060260]; response to bacterium [GO:0009617]; response to radiation [GO:0009314]" cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] metal ion binding [GO:0046872]; mitogen-activated protein kinase binding [GO:0051019]; myosin phosphatase activity [GO:0017018]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine phosphatase activity [GO:0004722] 0.87938 0.012251 SGVNRVVWK 0 0 0 0 0 0 0 0 0 0 9.46361 0 0 0 0 0 0 10.3486 0 0 0 0 0 0 0 8.87486 0 O15303 GRM6_HUMAN Metabotropic glutamate receptor 6 (mGluR6) GRM6 GPRC1F MGLUR6 Homo sapiens (Human) "chemical synaptic transmission [GO:0007268]; detection of light stimulus involved in visual perception [GO:0050908]; detection of visible light [GO:0009584]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; locomotory behavior [GO:0007626]; positive regulation of calcium ion import across plasma membrane [GO:1905665]; regulation of synaptic transmission, glutamatergic [GO:0051966]; retina development in camera-type eye [GO:0060041]" dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; new growing cell tip [GO:0035841]; plasma membrane [GO:0005886]; synapse [GO:0045202] adenylate cyclase inhibiting G protein-coupled glutamate receptor activity [GO:0001640]; G protein-coupled receptor activity [GO:0004930]; glutamate receptor activity [GO:0008066]; protein homodimerization activity [GO:0042803] 0.93268 -1.2779 KCTGEERIGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3044 0 O15305 PMM2_HUMAN Phosphomannomutase 2 (PMM 2) (EC 5.4.2.8) PMM2 Homo sapiens (Human) GDP-mannose biosynthetic process [GO:0009298]; mannose metabolic process [GO:0006013]; protein glycosylation [GO:0006486]; protein N-linked glycosylation [GO:0006487] cytosol [GO:0005829]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654] metal ion binding [GO:0046872]; phosphomannomutase activity [GO:0004615] 0.22747 0.86036 IGVVGGSDFEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.99591 0 0 0 9.98456 O15315 RA51B_HUMAN DNA repair protein RAD51 homolog 2 (R51H2) (RAD51 homolog B) (Rad51B) (RAD51-like protein 1) RAD51B RAD51L1 REC2 Homo sapiens (Human) blastocyst growth [GO:0001832]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; reciprocal meiotic recombination [GO:0007131]; somite development [GO:0061053] nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Rad51B-Rad51C-Rad51D-XRCC2 complex [GO:0033063]; replication fork [GO:0005657] "ATP binding [GO:0005524]; ATP-dependent activity, acting on DNA [GO:0008094]; ATP-dependent DNA damage sensor activity [GO:0140664]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; single-stranded DNA binding [GO:0003697]" 0.74411 0.32028 LILQYLDSER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.98607 10.3593 0 0 0 0 0 0 0 0 0 0 0 O15321 TM9S1_HUMAN Transmembrane 9 superfamily member 1 (MP70 protein family member) (hMP70) TM9SF1 Homo sapiens (Human) autophagy [GO:0006914]; protein localization to membrane [GO:0072657] autophagosome membrane [GO:0000421]; cytoplasmic vesicle [GO:0031410]; lysosomal membrane [GO:0005765]; membrane [GO:0016020] 0.92376 -1.0498 MAESLYEIRFRENVEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9595 0 O15327 INP4B_HUMAN "Inositol polyphosphate 4-phosphatase type II (Type II inositol 3,4-bisphosphate 4-phosphatase) (EC 3.1.3.66)" INPP4B Homo sapiens (Human) inositol phosphate metabolic process [GO:0043647]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829] "inositol-1,3,4-trisphosphate 4-phosphatase activity [GO:0017161]; inositol-3,4-bisphosphate 4-phosphatase activity [GO:0052828]; phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity [GO:0016316]" 0.89775 -0.6501 DCMGEVVNR 0 0 0 0 0 0 0 0 0 9.5109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15344 TRI18_HUMAN E3 ubiquitin-protein ligase Midline-1 (EC 2.3.2.27) (Midin) (Putative transcription factor XPRF) (RING finger protein 59) (RING finger protein Midline-1) (RING-type E3 ubiquitin transferase Midline-1) (Tripartite motif-containing protein 18) MID1 FXY RNF59 TRIM18 XPRF Homo sapiens (Human) microtubule cytoskeleton organization [GO:0000226]; negative regulation of microtubule depolymerization [GO:0007026]; pattern specification process [GO:0007389]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein localization to microtubule [GO:0035372]; regulation of microtubule cytoskeleton organization [GO:0070507] centriolar satellite [GO:0034451]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; spindle [GO:0005819] enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; phosphoprotein binding [GO:0051219]; protein homodimerization activity [GO:0042803]; transferase activity [GO:0016740]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270] 0.96402 -2.2197 AINQAGSR 0 0 0 0 0 0 9.98114 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15347 HMGB3_HUMAN High mobility group protein B3 (High mobility group protein 2a) (HMG-2a) (High mobility group protein 4) (HMG-4) HMGB3 HMG2A HMG4 Homo sapiens (Human) DNA geometric change [GO:0032392]; DNA recombination [GO:0006310]; innate immune response [GO:0045087]; negative regulation of B cell differentiation [GO:0045578]; negative regulation of myeloid cell differentiation [GO:0045638]; regulation of transcription by RNA polymerase II [GO:0006357] chromosome [GO:0005694]; cytoplasm [GO:0005737]; nucleus [GO:0005634] "DNA binding, bending [GO:0008301]; double-stranded DNA binding [GO:0003690]; four-way junction DNA binding [GO:0000400]; RNA binding [GO:0003723]" 0 11.789 KNPEVPVNFAEFSK 9.3699 0 10.1904 0 0 0 11.5995 11.8231 12.2064 8.26205 0 0 0 8.69457 0 0 0 0 0 0 0 0 0 0 0 0 0 O15353 FOXN1_HUMAN Forkhead box protein N1 (Winged-helix transcription factor nude) FOXN1 RONU WHN Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; blood vessel morphogenesis [GO:0048514]; defense response [GO:0006952]; epidermis development [GO:0008544]; hair follicle development [GO:0001942]; keratinocyte differentiation [GO:0030216]; lymphoid lineage cell migration into thymus [GO:0097535]; nail development [GO:0035878]; positive regulation of epithelial cell differentiation [GO:0030858]; positive regulation of hair follicle development [GO:0051798]; regulation of positive thymic T cell selection [GO:1902232]; regulation of transcription by RNA polymerase II [GO:0006357]; T cell homeostasis [GO:0043029]; T cell lineage commitment [GO:0002360]; thymus epithelium morphogenesis [GO:0097536] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; transcription cis-regulatory region binding [GO:0000976]" 0.54736 0.5664 TGSLPVSEIYNFMTEHFPYFKTAPDGWK 0 0 0 9.94335 0 0 0 0 10.9067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15354 GPR37_HUMAN Prosaposin receptor GPR37 (Endothelin B receptor-like protein 1) (ETBR-LP-1) (G-protein coupled receptor 37) (Parkin-associated endothelin receptor-like receptor) (PAELR) GPR37 Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; dendrite development [GO:0016358]; dopamine biosynthetic process [GO:0042416]; G protein-coupled receptor signaling pathway [GO:0007186]; locomotion involved in locomotory behavior [GO:0031987]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; neuropeptide signaling pathway [GO:0007218]; positive regulation of dopamine metabolic process [GO:0045964]; positive regulation of MAPK cascade [GO:0043410] cell surface [GO:0009986]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; synapse [GO:0045202]; ubiquitin ligase complex [GO:0000151] G protein-coupled peptide receptor activity [GO:0008528]; G protein-coupled receptor activity [GO:0004930]; heat shock protein binding [GO:0031072]; Hsp70 protein binding [GO:0030544]; neuropeptide binding [GO:0042923]; neuropeptide receptor activity [GO:0008188]; PDZ domain binding [GO:0030165]; peptide binding [GO:0042277]; prosaposin receptor activity [GO:0036505]; ubiquitin protein ligase binding [GO:0031625] 0.92432 -1.1747 GARGQEPSETLGR 0 0 0 0 0 0 0 0 0 0 0 0 9.247 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15357 SHIP2_HUMAN "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (EC 3.1.3.86) (Inositol polyphosphate phosphatase-like protein 1) (INPPL-1) (Protein 51C) (SH2 domain-containing inositol 5'-phosphatase 2) (SH2 domain-containing inositol phosphatase 2) (SHIP-2)" INPPL1 SHIP2 Homo sapiens (Human) actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; endochondral ossification [GO:0001958]; endocytosis [GO:0006897]; establishment of mitotic spindle orientation [GO:0000132]; glucose metabolic process [GO:0006006]; immune system process [GO:0002376]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of insulin-like growth factor receptor signaling pathway [GO:0043569]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; post-embryonic development [GO:0009791]; regulation of actin filament organization [GO:0110053]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; response to insulin [GO:0032868]; ruffle assembly [GO:0097178] basal plasma membrane [GO:0009925]; cytosol [GO:0005829]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; lamellipodium [GO:0030027]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; spindle pole [GO:0000922] "actin binding [GO:0003779]; inositol-polyphosphate 5-phosphatase activity [GO:0004445]; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity [GO:0034485]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]" 0.82277 0.21628 ISHVSTSSVK 0 0 0 0 0 0 9.97685 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.09 0 0 0 0 O15360 FANCA_HUMAN Fanconi anemia group A protein (Protein FACA) FANCA FAA FACA FANCH Homo sapiens (Human) DNA repair [GO:0006281]; female gonad development [GO:0008585]; interstrand cross-link repair [GO:0036297]; male gonad development [GO:0008584]; male meiotic nuclear division [GO:0007140]; protein monoubiquitination [GO:0006513]; protein-containing complex assembly [GO:0065003]; regulation of CD40 signaling pathway [GO:2000348]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of germ cell proliferation [GO:1905936]; regulation of inflammatory response [GO:0050727]; regulation of regulatory T cell differentiation [GO:0045589] chromatin [GO:0000785]; cytoplasm [GO:0005737]; Fanconi anaemia nuclear complex [GO:0043240]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.9695 -3.1494 ASFGSTRGYHGCSK 10.1906 0 0 9.46117 9.54926 9.37443 9.70453 9.92735 9.66757 13.5223 0 12.0587 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15371 EIF3D_HUMAN Eukaryotic translation initiation factor 3 subunit D (eIF3d) (Eukaryotic translation initiation factor 3 subunit 7) (eIF-3-zeta) (eIF3 p66) EIF3D EIF3S7 Homo sapiens (Human) cap-dependent translational initiation [GO:0002191]; formation of cytoplasmic translation initiation complex [GO:0001732]; IRES-dependent viral translational initiation [GO:0075522]; positive regulation of mRNA binding [GO:1902416]; positive regulation of translation [GO:0045727]; translational initiation [GO:0006413]; viral translational termination-reinitiation [GO:0075525] "cytosol [GO:0005829]; eukaryotic 43S preinitiation complex [GO:0016282]; eukaryotic 48S preinitiation complex [GO:0033290]; eukaryotic translation initiation factor 3 complex [GO:0005852]; eukaryotic translation initiation factor 3 complex, eIF3m [GO:0071541]; membrane [GO:0016020]; synapse [GO:0045202]" mRNA cap binding [GO:0098808]; RNA binding [GO:0003723]; translation initiation factor activity [GO:0003743] 0.93015 -1.2436 IFHTVTTTDDPVIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.61591 0 0 0 0 0 0 0 0 O15372 EIF3H_HUMAN Eukaryotic translation initiation factor 3 subunit H (eIF3h) (Eukaryotic translation initiation factor 3 subunit 3) (eIF-3-gamma) (eIF3 p40 subunit) EIF3H EIF3S3 Homo sapiens (Human) formation of cytoplasmic translation initiation complex [GO:0001732]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413] "cytosol [GO:0005829]; eukaryotic 43S preinitiation complex [GO:0016282]; eukaryotic 48S preinitiation complex [GO:0033290]; eukaryotic translation initiation factor 3 complex [GO:0005852]; eukaryotic translation initiation factor 3 complex, eIF3m [GO:0071541]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; polysomal ribosome [GO:0042788]" metal-dependent deubiquitinase activity [GO:0140492]; metallopeptidase activity [GO:0008237]; RNA binding [GO:0003723]; translation initiation factor activity [GO:0003743] 0.96755 -2.8565 LMEVCKEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.16335 0 0 0 0 9.12975 O15381 NVL_HUMAN Nuclear valosin-containing protein-like (NVLp) (Nuclear VCP-like protein) NVL NVL2 Homo sapiens (Human) positive regulation of protein binding [GO:0032092]; positive regulation of telomerase activity [GO:0051973]; regulation of protein localization to nucleolus [GO:1904749]; ribosomal large subunit biogenesis [GO:0042273]; ribosome biogenesis [GO:0042254]; rRNA processing [GO:0006364] membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; telomerase holoenzyme complex [GO:0005697] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; preribosome binding [GO:1990275]; RNA binding [GO:0003723] 0.19309 0.93539 ETGASVR 0 0 0 10.6411 0 0 0 0 0 0 0 0 0 0 0 9.29978 0 0 0 0 0 0 0 0 0 0 0 O15382 BCAT2_HUMAN "Branched-chain-amino-acid aminotransferase, mitochondrial (BCAT(m)) (EC 2.6.1.42) (Placental protein 18) (PP18)" BCAT2 BCATM BCT2 ECA40 Homo sapiens (Human) branched-chain amino acid biosynthetic process [GO:0009082]; cellular response to leukemia inhibitory factor [GO:1990830]; isoleucine catabolic process [GO:0006550]; leucine biosynthetic process [GO:0009098]; lipid metabolic process [GO:0006629]; regulation of hormone levels [GO:0010817]; valine biosynthetic process [GO:0009099] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] branched-chain-amino-acid transaminase activity [GO:0004084]; L-isoleucine transaminase activity [GO:0052656]; L-leucine transaminase activity [GO:0052654]; L-leucine:2-oxoglutarate aminotransferase activity [GO:0050048]; L-valine transaminase activity [GO:0052655] 0.56376 0.51424 LELLECIR 0 0 0 0 0 0 0 0 0 10.7896 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15394 NCAM2_HUMAN Neural cell adhesion molecule 2 (N-CAM-2) (NCAM-2) NCAM2 NCAM21 Homo sapiens (Human) axonal fasciculation [GO:0007413]; neuron cell-cell adhesion [GO:0007158]; sensory perception of smell [GO:0007608] axon [GO:0030424]; membrane [GO:0016020]; nuclear body [GO:0016604]; plasma membrane [GO:0005886] identical protein binding [GO:0042802] 0.96214 -2.0355 IIELSQTTAK 0 0 0 0 0 0 0 0 0 0 0 0 9.63181 0 0 0 0 0 0 0 9.24631 0 0 0 0 0 0 O15399 NMDE4_HUMAN "Glutamate receptor ionotropic, NMDA 2D (GluN2D) (EB11) (Glutamate [NMDA] receptor subunit epsilon-4) (N-methyl D-aspartate receptor subtype 2D) (NMDAR2D) (NR2D)" GRIN2D GluN2D NMDAR2D Homo sapiens (Human) "adult locomotory behavior [GO:0008344]; brain development [GO:0007420]; calcium ion transmembrane import into cytosol [GO:0097553]; excitatory chemical synaptic transmission [GO:0098976]; excitatory postsynaptic potential [GO:0060079]; ionotropic glutamate receptor signaling pathway [GO:0035235]; long-term synaptic potentiation [GO:0060291]; monoatomic cation transmembrane transport [GO:0098655]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; regulation of monoatomic cation transmembrane transport [GO:1904062]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of sensory perception of pain [GO:0051930]; regulation of synaptic plasticity [GO:0048167]; startle response [GO:0001964]; synaptic transmission, glutamatergic [GO:0035249]" endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; NMDA selective glutamate receptor complex [GO:0017146]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic active zone membrane [GO:0048787] glutamate binding [GO:0016595]; glutamate-gated calcium ion channel activity [GO:0022849]; ionotropic glutamate receptor activity [GO:0004970]; ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; neurotransmitter binding [GO:0042165]; NMDA glutamate receptor activity [GO:0004972]; transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated monoatomic cation channel activity [GO:0022843] 0.96788 -2.8794 AGSWDYLPPR 0 0 0 0 0 0 0 0 0 11.4002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.21575 0 O15400 STX7_HUMAN Syntaxin-7 STX7 Homo sapiens (Human) intracellular protein transport [GO:0006886]; organelle assembly [GO:0070925]; organelle localization [GO:0051640]; positive regulation of receptor localization to synapse [GO:1902685]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; regulation of protein localization to plasma membrane [GO:1903076]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906] azurophil granule [GO:0042582]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endomembrane system [GO:0012505]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; immunological synapse [GO:0001772]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; SNARE complex [GO:0031201]; synaptic vesicle [GO:0008021]; tertiary granule [GO:0070820]; vesicle [GO:0031982] chloride channel inhibitor activity [GO:0019869]; SNAP receptor activity [GO:0005484]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905] 0.9217 -1.126 ASSRVSGSFPEDSSK 0 0 0 0 0 0 8.93351 9.05363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15405 TOX3_HUMAN TOX high mobility group box family member 3 (CAG trinucleotide repeat-containing gene F9 protein) (Trinucleotide repeat-containing gene 9 protein) TOX3 CAGF9 TNRC9 Homo sapiens (Human) apoptotic process [GO:0006915]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of transcription by RNA polymerase II [GO:0006357] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; phosphoprotein binding [GO:0051219]; protein homodimerization activity [GO:0042803]; transcription coactivator activity [GO:0003713] 0.93956 -1.3033 AIGEKRAAPDSGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.41244 0 0 0 0 0 0 0 0 0 0 O15417 TNC18_HUMAN Trinucleotide repeat-containing gene 18 protein (Long CAG trinucleotide repeat-containing gene 79 protein) TNRC18 CAGL79 KIAA1856 Homo sapiens (Human) cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654] chromatin binding [GO:0003682] 0.96917 -4.86 DTGEGKDGGTAGSEEPGAK 0 10.0349 0 0 9.14389 0 0 0 10.2256 11.9029 10.0399 13.6312 0 0 0 0 0 8.76188 0 0 0 9.82945 0 0 0 10.2438 0 O15438 MRP3_HUMAN ATP-binding cassette sub-family C member 3 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Canalicular multispecific organic anion transporter 2) (Multi-specific organic anion transporter D) (MOAT-D) (Multidrug resistance-associated protein 3) ABCC3 CMOAT2 MLP2 MRP3 Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; leukotriene transport [GO:0071716]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport [GO:0042908] basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; membrane [GO:0016020]; plasma membrane [GO:0005886] ABC-type bile acid transporter activity [GO:0015432]; ABC-type glutathione S-conjugate transporter activity [GO:0015431]; ABC-type transporter activity [GO:0140359]; ABC-type xenobiotic transporter activity [GO:0008559]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled inorganic anion transmembrane transporter activity [GO:0043225]; ATPase-coupled transmembrane transporter activity [GO:0042626]; glucuronoside transmembrane transporter activity [GO:0015164]; icosanoid transmembrane transporter activity [GO:0071714]; xenobiotic transmembrane transporter activity [GO:0042910] 0.95968 -1.9211 DFEIISDTK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.1307 0 0 0 0 0 0 0 0 0 0 0 0 0 O15439 MRP4_HUMAN ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) ABCC4 MOATB MRP4 Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; external side of apical plasma membrane [GO:0098591]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; platelet dense granule membrane [GO:0031088] 15-hydroxyprostaglandin dehydrogenase (NAD+) activity [GO:0016404]; ABC-type bile acid transporter activity [GO:0015432]; ABC-type glutathione S-conjugate transporter activity [GO:0015431]; ABC-type transporter activity [GO:0140359]; ABC-type xenobiotic transporter activity [GO:0008559]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled inorganic anion transmembrane transporter activity [GO:0043225]; ATPase-coupled transmembrane transporter activity [GO:0042626]; efflux transmembrane transporter activity [GO:0015562]; glutathione transmembrane transporter activity [GO:0034634]; guanine nucleotide transmembrane transporter activity [GO:0001409]; prostaglandin transmembrane transporter activity [GO:0015132]; purine nucleotide transmembrane transporter activity [GO:0015216]; urate transmembrane transporter activity [GO:0015143]; xenobiotic transmembrane transporter activity [GO:0042910] 0.97006 -3.2478 LRVAMCHMIYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0629 0 0 9.96953 10.441 0 O15440 MRP5_HUMAN ATP-binding cassette sub-family C member 5 (EC 7.6.2.-) (EC 7.6.2.2) (Multi-specific organic anion transporter C) (MOAT-C) (Multidrug resistance-associated protein 5) (SMRP) (pABC11) ABCC5 MRP5 Homo sapiens (Human) cAMP transport [GO:0070730]; cGMP transport [GO:0070731]; export across plasma membrane [GO:0140115]; folate transmembrane transport [GO:0098838]; glutathione transmembrane transport [GO:0034775]; heme transmembrane transport [GO:0035351]; hyaluronan biosynthetic process [GO:0030213]; purine nucleotide transport [GO:0015865]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport [GO:0042908] apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; endosome membrane [GO:0010008]; Golgi lumen [GO:0005796]; membrane [GO:0016020]; plasma membrane [GO:0005886] ABC-type xenobiotic transporter activity [GO:0008559]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled inorganic anion transmembrane transporter activity [GO:0043225]; ATPase-coupled transmembrane transporter activity [GO:0042626]; carbohydrate derivative transmembrane transporter activity [GO:1901505]; efflux transmembrane transporter activity [GO:0015562]; glutathione transmembrane transporter activity [GO:0034634]; heme transmembrane transporter activity [GO:0015232]; macromolecule transmembrane transporter activity [GO:0022884]; organic anion transmembrane transporter activity [GO:0008514]; purine nucleotide transmembrane transporter activity [GO:0015216]; xenobiotic transmembrane transporter activity [GO:0042910] 0.96941 -4.6419 ALLRHCK 0 0 0 8.67182 0 0 9.98456 9.78102 0 11.1122 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15444 CCL25_HUMAN C-C motif chemokine 25 (Chemokine TECK) (Small-inducible cytokine A25) (Thymus-expressed chemokine) CCL25 SCYA25 TECK Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell chemotaxis [GO:0060326]; cell surface receptor signaling pathway [GO:0007166]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to type II interferon [GO:0071346]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; eosinophil chemotaxis [GO:0048245]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; killing of cells of another organism [GO:0031640]; lymphocyte chemotaxis [GO:0048247]; monocyte chemotaxis [GO:0002548]; negative regulation of leukocyte tethering or rolling [GO:1903237]; neutrophil chemotaxis [GO:0030593]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547] extracellular region [GO:0005576]; extracellular space [GO:0005615] CCR chemokine receptor binding [GO:0048020]; CCR10 chemokine receptor binding [GO:0031735]; chemokine activity [GO:0008009]; chemokine receptor binding [GO:0042379]; hormone activity [GO:0005179] 0.5907 0.4547 LSSGNSK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.73547 0 0 0 0 0 0 0 9.09548 0 9.0669 0 0 0 O15457 MSH4_HUMAN MutS protein homolog 4 (hMSH4) MSH4 Homo sapiens (Human) female gamete generation [GO:0007292]; homologous chromosome pairing at meiosis [GO:0007129]; mismatch repair [GO:0006298]; ovarian follicle development [GO:0001541]; reciprocal meiotic recombination [GO:0007131]; spermatogenesis [GO:0007283] chromosome [GO:0005694]; nucleus [GO:0005634]; recombination nodule [GO:0005713]; synaptonemal complex [GO:0000795] ATP binding [GO:0005524]; ATP-dependent DNA damage sensor activity [GO:0140664]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; mismatched DNA binding [GO:0030983] 0.96236 -2.4496 LSKGLTEEKNYGLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.38612 0 0 0 0 0 O15466 SIA8E_HUMAN "Alpha-2,8-sialyltransferase 8E (EC 2.4.99.-) (Sialyltransferase 8E) (SIAT8-E) (Sialyltransferase St8Sia V) (ST8SiaV)" ST8SIA5 SIAT8E Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; glycosphingolipid biosynthetic process [GO:0006688]; N-glycan processing [GO:0006491]; oligosaccharide metabolic process [GO:0009311]; protein glycosylation [GO:0006486] Golgi membrane [GO:0000139] "alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity [GO:0003828]; sialyltransferase activity [GO:0008373]" 0.91881 -0.89591 EINSADFVFR 8.77426 0 0 0 14.2731 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.59178 0 9.81598 O15479 MAGB2_HUMAN Melanoma-associated antigen B2 (Cancer/testis antigen 3.2) (CT3.2) (DSS-AHC critical interval MAGE superfamily 6) (DAM6) (MAGE XP-2 antigen) (MAGE-B2 antigen) MAGEB2 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] 0.011933 1.726 EHFPEILK 0 0 0 8.39849 0 0 0 0 0 11.1492 0 0 0 10.0591 10.5128 11.0061 0 11.41 0 0 0 0 0 0 0 0 0 O15484 CAN5_HUMAN Calpain-5 (EC 3.4.22.-) (Calpain htra-3) (New calpain 3) (nCL-3) CAPN5 NCL3 Homo sapiens (Human) proteolysis [GO:0006508]; signal transduction [GO:0007165] cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; synapse [GO:0045202] calcium-dependent cysteine-type endopeptidase activity [GO:0004198] 0.95539 -1.5604 VEENRQYR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.95915 10.0316 0 0 0 0 0 0 0 0 0 0 0 0 O15488 GLYG2_HUMAN Glycogenin-2 (GN-2) (GN2) (EC 2.4.1.186) GYG2 Homo sapiens (Human) glycogen biosynthetic process [GO:0005978] cytoplasm [GO:0005737]; cytosol [GO:0005829] glycogenin glucosyltransferase activity [GO:0008466]; glycosyltransferase activity [GO:0016757]; metal ion binding [GO:0046872]; UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity [GO:0102751] 0.96106 -2.5603 QFGSSAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.72533 0 0 0 0 O15492 RGS16_HUMAN Regulator of G-protein signaling 16 (RGS16) (A28-RGS14P) (Retinal-specific RGS) (RGS-r) (hRGS-r) (Retinally abundant regulator of G-protein signaling) RGS16 RGSR Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; visual perception [GO:0007601] cytoplasm [GO:0005737]; membrane [GO:0016020]; plasma membrane [GO:0005886] calmodulin binding [GO:0005516]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924] 0.91482 -0.81532 LASRAHQIFEEFICSEAPK 0 0 0 0 0 0 0 0 0 0 0 0 10.8919 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15498 YKT6_HUMAN Synaptobrevin homolog YKT6 (EC 2.3.1.-) YKT6 Homo sapiens (Human) "endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle docking involved in exocytosis [GO:0006904]; vesicle targeting [GO:0006903]" apical dendrite [GO:0097440]; basal dendrite [GO:0097441]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; SNARE complex [GO:0031201]; transport vesicle [GO:0030133] cadherin binding [GO:0045296]; protein-cysteine S-palmitoyltransferase activity [GO:0019706]; SNAP receptor activity [GO:0005484] 0.93996 -1.307 AFYKTARK 0 12.8506 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15514 RPB4_HUMAN DNA-directed RNA polymerase II subunit RPB4 (RNA polymerase II subunit B4) (DNA-directed RNA polymerase II subunit D) (RNA polymerase II 16 kDa subunit) (RPB16) POLR2D Homo sapiens (Human) recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex [GO:0034402]; transcription by RNA polymerase II [GO:0006366]; transcription initiation at RNA polymerase II promoter [GO:0006367] "cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II, core complex [GO:0005665]" nucleotide binding [GO:0000166]; translation initiation factor binding [GO:0031369] 0.62388 0.41234 AAGGSDPR 0 0 0 0 0 0 0 0 0 0 0 0 0 8.34696 0 0 0 0 0 0 0 0 0 0 0 9.63679 0 O15523 DDX3Y_HUMAN "ATP-dependent RNA helicase DDX3Y (EC 3.6.4.13) (DEAD box protein 3, Y-chromosomal)" DDX3Y DBY Homo sapiens (Human) cell differentiation [GO:0030154]; gamete generation [GO:0007276] cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P granule [GO:0043186] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA binding [GO:0003677]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.92221 -0.94036 DAYSSFGSRDSR 0 0 0 0 0 0 0 0 10.936 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.12469 0 0 O15527 OGG1_HUMAN N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase (EC 3.2.2.-); DNA-(apurinic or apyrimidinic site) lyase (AP lyase) (EC 4.2.99.18)] OGG1 MMH MUTM OGH1 Homo sapiens (Human) "acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; depurination [GO:0045007]; depyrimidination [GO:0045008]; DNA damage response [GO:0006974]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair [GO:0006289]; regulation of DNA-templated transcription [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]; response to xenobiotic stimulus [GO:0009410]" cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] "8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]" 0.95264 -1.4736 ARYVSASAR 0 0 0 0 0 0 0 9.73395 0 0 8.67444 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15528 CP27B_HUMAN "25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial (EC 1.14.15.18) (25-OHD-1 alpha-hydroxylase) (25-hydroxyvitamin D(3) 1-alpha-hydroxylase) (VD3 1A hydroxylase) (Calcidiol 1-monooxygenase) (Cytochrome P450 subfamily XXVIIB polypeptide 1) (Cytochrome P450C1 alpha) (Cytochrome P450VD1-alpha) (Cytochrome p450 27B1)" CYP27B1 CYP1ALPHA CYP27B Homo sapiens (Human) bone mineralization [GO:0030282]; calcitriol biosynthetic process from calciol [GO:0036378]; calcium ion homeostasis [GO:0055074]; calcium ion transport [GO:0006816]; decidualization [GO:0046697]; G1 to G0 transition [GO:0070314]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of vitamin D 24-hydroxylase activity [GO:0010980]; positive regulation of vitamin D receptor signaling pathway [GO:0070564]; regulation of bone mineralization [GO:0030500]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to type II interferon [GO:0034341]; response to vitamin D [GO:0033280]; vitamin D catabolic process [GO:0042369]; vitamin D metabolic process [GO:0042359]; vitamin metabolic process [GO:0006766] cytoplasm [GO:0005737]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739] calcidiol 1-monooxygenase activity [GO:0004498]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; secalciferol 1-monooxygenase activity [GO:0062185] 0.89815 -0.66971 DWDQMFAFAQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.79795 0 0 0 0 0 0 0 0 0 0 0 0 O15529 GPR42_HUMAN G-protein coupled receptor 42 GPR42 GPR42P Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930] 0.93282 -1.2782 GGSHRRQR 0 0 0 0 0 0 9.48981 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15535 ZSC9_HUMAN Zinc finger and SCAN domain-containing protein 9 (Cell proliferation-inducing gene 12 protein) (PRD51) (Zinc finger protein 193) ZSCAN9 ZNF193 PIG12 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.91294 -0.82212 EIFRRHFR 0 0 0 0 0 9.13681 0 0 9.33671 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15539 RGS5_HUMAN Regulator of G-protein signaling 5 (RGS5) RGS5 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; regulation of G protein-coupled receptor signaling pathway [GO:0008277] cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886] GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924] 0.9338 -1.2897 SPAKMAEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.30943 9.47669 9.35592 0 0 0 0 0 0 0 0 0 O15541 R113A_HUMAN E3 ubiquitin-protein ligase RNF113A (EC 2.3.2.27) (Cwc24 homolog) (RING finger protein 113A) (Zinc finger protein 183) RNF113A RNF113 ZNF183 Homo sapiens (Human) "DNA repair [GO:0006281]; isopeptide cross-linking via N6-glycyl-L-lysine [GO:0018276]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; protein ubiquitination [GO:0016567]; snoRNA splicing [GO:0034247]" nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type precatalytic spliceosome [GO:0071005]; U2-type spliceosomal complex [GO:0005684] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630] 0.8559 0.10392 HGWQIERELDEGR 0 0 0 0 0 0 0 9.51491 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O15547 P2RX6_HUMAN P2X purinoceptor 6 (P2X6) (ATP receptor) (P2XM) (Purinergic receptor) (Purinergic receptor P2X-like 1) P2RX6 P2RXL1 P2X6 Homo sapiens (Human) muscle contraction [GO:0006936]; response to ATP [GO:0033198]; signal transduction [GO:0007165] cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic specialization membrane [GO:0099634]; receptor complex [GO:0043235] ATP binding [GO:0005524]; channel activity [GO:0015267]; extracellularly ATP-gated monoatomic cation channel activity [GO:0004931]; protein-containing complex binding [GO:0044877]; purinergic nucleotide receptor activity [GO:0001614]; transmembrane signaling receptor activity [GO:0004888] 0.89028 -0.47589 GVSVTQIK 0 0 0 0 0 0 0 11.2015 0 0 0 0 0 0 0 0 0 0 0 8.25941 0 0 0 0 9.91983 0 0 O15550 KDM6A_HUMAN Lysine-specific demethylase 6A (EC 1.14.11.68) (Histone demethylase UTX) (Ubiquitously-transcribed TPR protein on the X chromosome) (Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein) ([histone H3]-trimethyl-L-lysine(27) demethylase 6A) KDM6A UTX Homo sapiens (Human) chromatin remodeling [GO:0006338]; histone H3-K27 demethylation [GO:0071557]; histone H3-K4 methylation [GO:0051568]; regulation of gene expression [GO:0010468] histone methyltransferase complex [GO:0035097]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin DNA binding [GO:0031490]; histone demethylase activity [GO:0032452]; histone H3K27me2/H3K27me3 demethylase activity [GO:0071558]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.95472 -1.6052 KTYIVHCQDCARK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.34877 0 0 O15551 CLD3_HUMAN Claudin-3 (Clostridium perfringens enterotoxin receptor 2) (CPE-R 2) (CPE-receptor 2) (Rat ventral prostate.1 protein homolog) (hRVP1) CLDN3 C7orf1 CPETR2 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; bicellular tight junction assembly [GO:0070830]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; cell junction maintenance [GO:0034331]; epithelial cell morphogenesis [GO:0003382]; establishment of endothelial blood-brain barrier [GO:0014045]; maintenance of blood-brain barrier [GO:0035633]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of wound healing [GO:0061045]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of cell junction assembly [GO:1901890]; positive regulation of cell migration [GO:0030335]; positive regulation of gene expression [GO:0010628]; positive regulation of metallopeptidase activity [GO:1905050]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of wound healing [GO:0090303]; regulation of cell morphogenesis [GO:0022604]; regulation of membrane permeability [GO:0090559]; regulation of transepithelial transport [GO:0150111]; response to ethanol [GO:0045471]; response to Gram-positive bacterium [GO:0140459]; response to hypoxia [GO:0001666] apical junction complex [GO:0043296]; apicolateral plasma membrane [GO:0016327]; bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; lateral plasma membrane [GO:0016328]; membrane [GO:0016020]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; tight junction [GO:0070160] identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; transmembrane signaling receptor activity [GO:0004888] 0.30871 0.80148 DFYNPVVPEAQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.63474 9.55205 0 O15553 MEFV_HUMAN Pyrin (Marenostrin) MEFV MEF TRIM20 Homo sapiens (Human) inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of autophagy [GO:0010508]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; protein ubiquitination [GO:0016567]; pyroptosis [GO:0070269]; pyroptosome complex assembly [GO:1904270]; regulation of gene expression [GO:0010468]; regulation of interleukin-1 beta production [GO:0032651]; response to type II interferon [GO:0034341] autophagosome [GO:0005776]; canonical inflammasome complex [GO:0061702]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; lamellipodium [GO:0030027]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726] actin binding [GO:0003779]; identical protein binding [GO:0042802]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.89774 -0.67991 ASEGLDAQGKPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2479 0 0 0 0 0 0 0 0 0 0 0 O15554 KCNN4_HUMAN Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (SKCa 4) (SKCa4) (IKCa1) (IK1) (KCa3.1) (KCa4) (Putative Gardos channel) KCNN4 IK1 IKCA1 KCA4 SK4 Homo sapiens (Human) calcium ion transport [GO:0006816]; cell volume homeostasis [GO:0006884]; defense response [GO:0006952]; establishment of localization in cell [GO:0051649]; immune system process [GO:0002376]; phospholipid translocation [GO:0045332]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein secretion [GO:0050714]; positive regulation of T cell receptor signaling pathway [GO:0050862]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; saliva secretion [GO:0046541]; stabilization of membrane potential [GO:0030322] cytosol [GO:0005829]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; voltage-gated potassium channel complex [GO:0008076] calcium-activated potassium channel activity [GO:0015269]; calmodulin binding [GO:0005516]; Intermediate conductance calcium-activated potassium channel activity [GO:0022894]; potassium channel activity [GO:0005267]; protein phosphatase binding [GO:0019903]; small conductance calcium-activated potassium channel activity [GO:0016286] 0.96534 -2.3732 DWRVALTGR 0 10.2898 0 0 0 0 0 0 10.4651 0 0 0 8.73454 0 9.53002 0 11.6063 0 0 0 0 0 0 0 0 0 0 O43143 DHX15_HUMAN ATP-dependent RNA helicase DHX15 (EC 3.6.4.13) (ATP-dependent RNA helicase #46) (DEAH box protein 15) (Splicing factor Prp43) (hPrp43) DHX15 DBP1 DDX15 Homo sapiens (Human) "antiviral innate immune response [GO:0140374]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; response to alkaloid [GO:0043279]; response to toxic substance [GO:0009636]; RNA splicing [GO:0008380]" nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U12-type spliceosomal complex [GO:0005689] "ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent activity, acting on RNA [GO:0008186]; double-stranded RNA binding [GO:0003725]; helicase activity [GO:0004386]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]" 0.91995 -0.92446 AGTDGKDR 0 10.0463 0 0 0 0 0 0 0 0 0 0 15.7516 0 15.935 0 0 0 0 15.5016 0 0 0 0 0 0 11.2875 O43149 ZZEF1_HUMAN Zinc finger ZZ-type and EF-hand domain-containing protein 1 ZZEF1 KIAA0399 Homo sapiens (Human) calcium ion binding [GO:0005509]; histone reader activity [GO:0140566]; lysine-acetylated histone binding [GO:0070577]; methylated histone binding [GO:0035064]; zinc ion binding [GO:0008270] 0.96725 -2.8216 DLAVDLIEK 0 0 0 0 0 0 0 0 0 0 0 12.7084 0 0 0 8.54593 0 0 10.4415 0 0 0 9.09191 0 0 0 0 O43150 ASAP2_HUMAN "Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 (Development and differentiation-enhancing factor 2) (Paxillin-associated protein with ARF GAP activity 3) (PAG3) (Pyk2 C-terminus-associated protein) (PAP)" ASAP2 DDEF2 KIAA0400 Homo sapiens (Human) positive regulation of GTPase activity [GO:0043547] cytosol [GO:0005829]; Golgi cisterna membrane [GO:0032580]; plasma membrane [GO:0005886] GTPase activator activity [GO:0005096]; metal ion binding [GO:0046872] 0.0083333 2.2069 DAANLAKEKQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.91725 0 10.7802 11.6006 0 0 0 0 11.0798 0 O43151 TET3_HUMAN Methylcytosine dioxygenase TET3 (EC 1.14.11.80) TET3 KIAA0401 Homo sapiens (Human) 5-methylcytosine catabolic process [GO:0006211]; chromatin organization [GO:0006325]; DNA demethylation [GO:0080111]; DNA demethylation of male pronucleus [GO:0044727]; oxidative demethylation [GO:0070989]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein O-linked glycosylation [GO:0006493] chromosome [GO:0005694]; cytoplasm [GO:0005737]; female pronucleus [GO:0001939]; male pronucleus [GO:0001940]; nucleus [GO:0005634] methyl-CpG binding [GO:0008327]; methylcytosine dioxygenase activity [GO:0070579]; zinc ion binding [GO:0008270] 0.96756 -2.9682 ELHATTPLK 13.1902 0 0 9.52282 0 0 0 0 0 0 9.14494 0 0 0 0 0 0 0 10.0287 11.7712 0 0 0 0 10.9669 0 0 O43155 FLRT2_HUMAN Leucine-rich repeat transmembrane protein FLRT2 (Fibronectin-like domain-containing leucine-rich transmembrane protein 2) FLRT2 KIAA0405 UNQ232/PRO265 Homo sapiens (Human) axon guidance [GO:0007411]; basement membrane organization [GO:0071711]; cell adhesion involved in heart morphogenesis [GO:0061343]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; positive regulation of synapse assembly [GO:0051965]; regulation of neuron migration [GO:2001222] cell-cell junction [GO:0005911]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; synapse [GO:0045202] chemorepellent activity [GO:0045499]; fibroblast growth factor receptor binding [GO:0005104]; protein-macromolecule adaptor activity [GO:0030674] 0.78345 0.25412 WVTEWLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.78329 0 10.2915 0 0 O43157 PLXB1_HUMAN Plexin-B1 (Semaphorin receptor SEP) PLXNB1 KIAA0407 PLXN5 SEP Homo sapiens (Human) cell migration [GO:0016477]; inhibitory synapse assembly [GO:1904862]; intracellular signal transduction [GO:0035556]; negative regulation of cell adhesion [GO:0007162]; negative regulation of osteoblast proliferation [GO:0033689]; neuron projection morphogenesis [GO:0048812]; ossification involved in bone maturation [GO:0043931]; positive regulation of axonogenesis [GO:0050772]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis [GO:1900220] extracellular region [GO:0005576]; plasma membrane [GO:0005886]; semaphorin receptor complex [GO:0002116] GTPase activating protein binding [GO:0032794]; GTPase activator activity [GO:0005096]; semaphorin receptor activity [GO:0017154]; semaphorin receptor binding [GO:0030215]; transmembrane signaling receptor activity [GO:0004888] 0.89873 -0.68257 DLQAQSRAFR 0 11.3162 9.51704 0 0 0 0 0 0 0 0 0 0 0 0 11.2572 0 11.4637 0 0 10.5221 0 0 0 0 0 0 O43159 RRP8_HUMAN Ribosomal RNA-processing protein 8 (EC 2.1.1.-) (Cerebral protein 1) (Nucleomethylin) RRP8 KIAA0409 NML hucep-1 Homo sapiens (Human) cellular response to glucose starvation [GO:0042149]; energy homeostasis [GO:0097009]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; methylation [GO:0032259]; negative regulation of cell cycle [GO:0045786]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of histone methylation [GO:0031062]; rDNA heterochromatin formation [GO:0000183]; regulation of G1 to G0 transition [GO:1903450]; regulation of transcription by glucose [GO:0046015]; rRNA processing [GO:0006364] chromatin silencing complex [GO:0005677]; cytosol [GO:0005829]; eNoSc complex [GO:0061773]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; rDNA heterochromatin [GO:0033553] methylated histone binding [GO:0035064]; RNA binding [GO:0003723]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757] 0.88014 0.0063225 FEDVRTFLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.25965 0 0 0 0 0 0 0 0 O43166 SI1L1_HUMAN Signal-induced proliferation-associated 1-like protein 1 (SIPA1-like protein 1) (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6-targeted protein 1) SIPA1L1 E6TP1 KIAA0440 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; activation of GTPase activity [GO:0090630]; ephrin receptor signaling pathway [GO:0048013]; regulation of axonogenesis [GO:0050770]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of synaptic plasticity [GO:0048167] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] ephrin receptor binding [GO:0046875]; GTPase activator activity [GO:0005096] 0.96365 -2.244 DVIGWTSTDTSLKIFYER 0 11.5732 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1504 0 0 0 0 0 0 0 9.55781 10.0966 0 0 O43167 ZBT24_HUMAN Zinc finger and BTB domain-containing protein 24 (Zinc finger protein 450) ZBTB24 KIAA0441 ZNF450 Homo sapiens (Human) hematopoietic progenitor cell differentiation [GO:0002244]; regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.89888 -0.57093 GDSGVLNEQIAAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.56824 0 0 0 0 O43169 CYB5B_HUMAN Cytochrome b5 type B (Cytochrome b5 outer mitochondrial membrane isoform) CYB5B CYB5M OMB5 Homo sapiens (Human) nitric oxide biosynthetic process [GO:0006809]; response to oxidative stress [GO:0006979]; xenobiotic metabolic process [GO:0006805] intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nitric-oxide synthase complex [GO:1903958] enzyme activator activity [GO:0008047]; heme binding [GO:0020037]; metal ion binding [GO:0046872] 0.88605 -0.33981 DPSKNDTCK 0 0 0 0 0 0 0 9.26641 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43172 PRP4_HUMAN U4/U6 small nuclear ribonucleoprotein Prp4 (PRP4 homolog) (hPrp4) (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4) PRPF4 PRP4 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]" Cajal body [GO:0015030]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; spliceosomal snRNP complex [GO:0097525]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 snRNP [GO:0071001]; U4/U6 x U5 tri-snRNP complex [GO:0046540] U4 snRNA binding [GO:0030621]; U6 snRNA binding [GO:0017070] 0.9672 -2.8309 FLGTTCYDR 0 0 0 9.53125 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.74786 0 0 0 0 0 0 O43173 SIA8C_HUMAN "Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase (EC 2.4.99.-) (Alpha-2,8-sialyltransferase 8C) (Alpha-2,8-sialyltransferase III) (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3) (Sialyltransferase 8C) (SIAT8-C) (Sialyltransferase St8Sia III) (ST8SiaIII)" ST8SIA3 SIAT8C Homo sapiens (Human) ganglioside biosynthetic process [GO:0001574]; glycoprotein metabolic process [GO:0009100]; glycosphingolipid biosynthetic process [GO:0006688]; N-glycan processing [GO:0006491]; oligosaccharide metabolic process [GO:0009311]; protein glycosylation [GO:0006486]; protein sialylation [GO:1990743] Golgi membrane [GO:0000139] "alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity [GO:0003828]; identical protein binding [GO:0042802]; sialic acid binding [GO:0033691]; sialyltransferase activity [GO:0008373]" 0.34875 0.76857 GTKFTTK 0 0 0 0 0 0 0 11.0717 9.0484 11.408 11.2756 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43175 SERA_HUMAN D-3-phosphoglycerate dehydrogenase (3-PGDH) (EC 1.1.1.95) (2-oxoglutarate reductase) (EC 1.1.1.399) (Malate dehydrogenase) (EC 1.1.1.37) PHGDH PGDH3 Homo sapiens (Human) brain development [GO:0007420]; G1 to G0 transition [GO:0070314]; gamma-aminobutyric acid metabolic process [GO:0009448]; glial cell development [GO:0021782]; glutamine metabolic process [GO:0006541]; glycine metabolic process [GO:0006544]; L-serine biosynthetic process [GO:0006564]; neural tube development [GO:0021915]; neuron projection development [GO:0031175]; regulation of gene expression [GO:0010468]; spinal cord development [GO:0021510]; taurine metabolic process [GO:0019530]; threonine metabolic process [GO:0006566] cytosol [GO:0005829]; extracellular exosome [GO:0070062] electron transfer activity [GO:0009055]; L-malate dehydrogenase activity [GO:0030060]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617] 0 6.7712 AGTGVDNVDLEAATR 0 0 0 0 0 0 0 8.94316 10.8949 0 8.76138 0 0 0 0 8.49113 0 9.28623 10.0724 9.84119 0 0 9.7295 0 11.9631 0 0 O43184 ADA12_HUMAN Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12) (EC 3.4.24.-) (Meltrin-alpha) ADAM12 MLTN UNQ346/PRO545 Homo sapiens (Human) cell adhesion [GO:0007155]; myoblast fusion [GO:0007520]; positive regulation of angiogenesis [GO:0045766]; proteolysis [GO:0006508] extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; SH3 domain binding [GO:0017124] 0.95447 -1.5014 ESFGGQKCGNR 0 0 0 0 0 0 0 0 0 9.82485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43186 CRX_HUMAN Cone-rod homeobox protein CRX CORD2 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell differentiation [GO:0030154]; nervous system development [GO:0007399]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; response to stimulus [GO:0050896]; visual perception [GO:0007601] chromatin [GO:0000785]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575] "DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; leucine zipper domain binding [GO:0043522]; nuclear receptor binding [GO:0016922]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.95547 -1.5852 QQRQQQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0651 0 0 0 0 0 0 0 O43187 IRAK2_HUMAN Interleukin-1 receptor-associated kinase-like 2 (IRAK-2) IRAK2 Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; intracellular signal transduction [GO:0035556]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein phosphorylation [GO:0006468]; regulation of cytokine-mediated signaling pathway [GO:0001959]; response to interleukin-1 [GO:0070555] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; nucleus [GO:0005634]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; molecular adaptor activity [GO:0060090]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674] 0.57244 0.48067 AEDEQEEGQPVR 0 0 9.17612 0 0 0 0 0 0 9.58184 0 0 0 0 0 8.99769 0 0 0 0 0 0 0 0 0 0 0 O43189 PHF1_HUMAN PHD finger protein 1 (Protein PHF1) (hPHF1) (Polycomb-like protein 1) (hPCl1) PHF1 PCL1 Homo sapiens (Human) chromatin organization [GO:0006325]; DNA repair-dependent chromatin remodeling [GO:0140861]; regulation of DNA-templated transcription [GO:0006355] cytosol [GO:0005829]; microtubule organizing center [GO:0005815]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; histone methyltransferase binding [GO:1990226]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methylated histone binding [GO:0035064]; transcription corepressor binding [GO:0001222] 0.96422 -2.3899 EVCLVQFEDDSQFLVLWK 0 0 0 10.8094 10.3642 10.1529 0 0 9.59169 0 10.7389 9.97097 0 0 0 0 0 9.5818 0 0 0 0 0 0 0 0 0 O43193 MTLR_HUMAN Motilin receptor (G-protein coupled receptor 38) MLNR GPR38 MTLR MTLR1 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186] cytosol [GO:0005829]; plasma membrane [GO:0005886] G protein-coupled peptide receptor activity [GO:0008528]; hormone binding [GO:0042562] 0.88882 -0.41507 EPPWPALPPCDERR 0 0 0 0 0 8.92875 0 0 0 0 0 0 8.6226 0 0 0 0 10.4897 0 8.92029 0 0 0 0 0 0 0 O43196 MSH5_HUMAN MutS protein homolog 5 (hMSH5) MSH5 Homo sapiens (Human) chiasma assembly [GO:0051026]; mismatch repair [GO:0006298] nucleus [GO:0005634] ATP binding [GO:0005524]; ATP-dependent DNA damage sensor activity [GO:0140664]; double-stranded DNA binding [GO:0003690]; mismatched DNA binding [GO:0030983] 0.7414 0.32253 TVYSALGLRDACR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5131 0 0 0 8.92923 8.57289 0 O43236 SEPT4_HUMAN Septin-4 (Bradeion beta) (Brain protein H5) (CE5B3 beta) (Cell division control-related protein 2) (hCDCREL-2) (Peanut-like protein 2) SEPTIN4 C17orf47 PNUTL2 SEP4 SEPT4 hucep-7 Homo sapiens (Human) apoptotic process [GO:0006915]; cytoskeleton-dependent cytokinesis [GO:0061640]; flagellated sperm motility [GO:0030317]; hematopoietic stem cell homeostasis [GO:0061484]; neuron migration [GO:0001764]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of protein ubiquitination [GO:0031398]; regulation of apoptotic process [GO:0042981]; regulation of exocytosis [GO:0017157]; spermatid differentiation [GO:0048515] axon [GO:0030424]; cell division site [GO:0032153]; cytosol [GO:0005829]; dendrite [GO:0030425]; microtubule cytoskeleton [GO:0015630]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; septin complex [GO:0031105]; septin ring [GO:0005940]; sperm annulus [GO:0097227]; synaptic vesicle [GO:0008021] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; molecular adaptor activity [GO:0060090]; structural molecule activity [GO:0005198] 0.93869 -1.2958 IQKQMKENY 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.1205 0 0 0 O43237 DC1L2_HUMAN "Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic) (LIC-2) (LIC53/55)" DYNC1LI2 DNCLI2 LIC2 Homo sapiens (Human) cellular response to nerve growth factor stimulus [GO:1990090]; centrosome localization [GO:0051642]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based movement [GO:0007018] centrosome [GO:0005813]; cytoplasmic dynein complex [GO:0005868]; cytosol [GO:0005829]; dynein complex [GO:0030286]; kinetochore [GO:0000776]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; microtubule [GO:0005874] ATP binding [GO:0005524]; dynein heavy chain binding [GO:0045504]; identical protein binding [GO:0042802] 0.76563 0.27873 LQGAEHGK 0 0 0 9.68435 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43242 PSMD3_HUMAN 26S proteasome non-ATPase regulatory subunit 3 (26S proteasome regulatory subunit RPN3) (26S proteasome regulatory subunit S3) (Proteasome subunit p58) PSMD3 Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of protein catabolic process [GO:0042176]; ubiquitin-dependent protein catabolic process [GO:0006511] "cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome accessory complex [GO:0022624]; proteasome complex [GO:0000502]; proteasome regulatory particle, lid subcomplex [GO:0008541]; secretory granule lumen [GO:0034774]" enzyme regulator activity [GO:0030234] 0.42872 0.66295 AIQLEYSEAR 0 0 0 0 0 0 0 0 0 0 11.2344 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43247 TEX33_HUMAN Testis-expressed protein 33 TEX33 C22orf33 EAN57 Homo sapiens (Human) 0.22108 0.88029 GAAEETK 8.75409 8.67687 8.70891 0 0 0 0 0 0 9.40559 0 0 9.45498 8.33401 0 0 0 0 0 0 0 0 0 0 0 0 0 O43248 HXC11_HUMAN Homeobox protein Hox-C11 (Homeobox protein Hox-3H) HOXC11 HOX3H Homo sapiens (Human) anatomical structure development [GO:0048856]; anterior/posterior pattern specification [GO:0009952]; embryonic digit morphogenesis [GO:0042733]; embryonic skeletal joint morphogenesis [GO:0060272]; endoderm development [GO:0007492]; metanephros development [GO:0001656]; organ induction [GO:0001759]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proximal/distal pattern formation [GO:0009954]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.91354 -0.78557 GEAKGEPEAPPASGLASR 13.353 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43255 SIAH2_HUMAN E3 ubiquitin-protein ligase SIAH2 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase SIAH2) (Seven in absentia homolog 2) (Siah-2) (hSiah2) SIAH2 Homo sapiens (Human) amyloid fibril formation [GO:1990000]; apoptotic process [GO:0006915]; canonical Wnt signaling pathway [GO:0060070]; cell cycle [GO:0007049]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of circadian rhythm [GO:0042752]; regulation of protein ubiquitination [GO:0031396]; rhythmic process [GO:0048511]; small GTPase mediated signal transduction [GO:0007264]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; intracellular membrane-bounded organelle [GO:0043231]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654] transcription corepressor activity [GO:0003714]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.75852 0.29256 LSCCPTCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.95641 0 0 0 O43264 ZW10_HUMAN Centromere/kinetochore protein zw10 homolog ZW10 Homo sapiens (Human) "cell division [GO:0051301]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; establishment of mitotic spindle orientation [GO:0000132]; Golgi organization [GO:0007030]; meiotic cell cycle [GO:0051321]; mitotic metaphase plate congression [GO:0007080]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint signaling [GO:0007094]; protein localization to kinetochore [GO:0034501]; protein transport [GO:0015031]; protein-containing complex assembly [GO:0065003]; regulation of exit from mitosis [GO:0007096]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]" cytosol [GO:0005829]; Dsl1/NZR complex [GO:0070939]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; kinetochore [GO:0000776]; kinetochore microtubule [GO:0005828]; lipid droplet [GO:0005811]; membrane [GO:0016020]; nucleus [GO:0005634]; RZZ complex [GO:1990423]; spindle pole [GO:0000922] centromeric DNA binding [GO:0019237] 0.96909 -4.5225 CQDVIVAAR 8.94058 9.0974 10.1077 0 0 11.6964 8.84781 0 0 16.6357 12.1646 11.8465 12.6665 10.8093 0 9.26971 0 0 0 0 0 11.7603 0 0 0 0 0 O43272 PROD_HUMAN "Proline dehydrogenase 1, mitochondrial (EC 1.5.5.2) (Proline oxidase) (Proline oxidase 2) (p53-induced gene 6 protein)" PRODH PIG6 POX2 PRODH2 Homo sapiens (Human) 4-hydroxyproline catabolic process [GO:0019470]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; positive regulation of cell death [GO:0010942]; proline catabolic process [GO:0006562]; proline catabolic process to glutamate [GO:0010133]; proline metabolic process [GO:0006560] intracellular membrane-bounded organelle [GO:0043231]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] FAD binding [GO:0071949]; proline dehydrogenase activity [GO:0004657] 0.95539 -1.5596 KATEMGVR 10.4427 10.3393 9.88391 0 8.81298 10.0819 0 10.2195 9.91338 0 9.11374 9.54714 0 9.5322 9.43181 10.5515 10.3974 9.8189 0 0 0 0 0 0 0 0 0 O43278 SPIT1_HUMAN Kunitz-type protease inhibitor 1 (Hepatocyte growth factor activator inhibitor type 1) (HAI-1) SPINT1 HAI1 UNQ223/PRO256 Homo sapiens (Human) branching involved in labyrinthine layer morphogenesis [GO:0060670]; cellular response to BMP stimulus [GO:0071773]; epidermis development [GO:0008544]; epithelium development [GO:0060429]; extracellular matrix organization [GO:0030198]; negative regulation of neural precursor cell proliferation [GO:2000178]; negative regulation of peptidase activity [GO:0010466]; neural tube closure [GO:0001843]; placenta blood vessel development [GO:0060674]; positive regulation of glial cell differentiation [GO:0045687] extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886] serine-type endopeptidase inhibitor activity [GO:0004867] 0.93005 -1.2346 QLRTQGFGGSGIPK 13.0126 12.7806 12.8511 10.4577 10.7329 10.7766 0 0 12.6359 0 13.0825 13.1401 11.3466 11.2289 0 0 12.1917 11.9692 8.38815 0 0 0 0 0 0 0 0 O43283 M3K13_HUMAN Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing kinase) (Mixed lineage kinase) (MLK) MAP3K13 LZK Homo sapiens (Human) JNK cascade [GO:0007254]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of axon extension [GO:0045773]; positive regulation of branching morphogenesis of a nerve [GO:1905492]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; stress-activated MAPK cascade [GO:0051403] cytoplasm [GO:0005737]; membrane [GO:0016020] ATP binding [GO:0005524]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; IkappaB kinase complex binding [GO:0106137]; JUN kinase kinase kinase activity [GO:0004706]; MAP kinase kinase kinase activity [GO:0004709]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activator activity [GO:0043539]; protein serine/threonine kinase activity [GO:0004674] 0.95945 -1.7302 EEVKKHFEK 0 0 0 0 0 0 0 0 0 13.8444 0 0 0 0 0 0 0 9.27803 0 0 0 0 0 0 0 0 0 O43290 SNUT1_HUMAN U4/U6.U5 tri-snRNP-associated protein 1 (SNU66 homolog) (hSnu66) (Squamous cell carcinoma antigen recognized by T-cells 1) (SART-1) (hSART-1) (U4/U6.U5 tri-snRNP-associated 110 kDa protein) (allergen Hom s 1) SART1 Homo sapiens (Human) "maturation of 5S rRNA [GO:0000481]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of cytotoxic T cell differentiation [GO:0045585]; spliceosomal snRNP assembly [GO:0000387]" Cajal body [GO:0015030]; catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540] RNA binding [GO:0003723] 0.86926 0.068361 GLAAALLLCQNK 9.01475 0 0 0 0 0 0 0 0 0 0 8.82868 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0342 O43292 GPAA1_HUMAN Glycosylphosphatidylinositol anchor attachment 1 protein (GPI anchor attachment protein 1) (GAA1 protein homolog) (hGAA1) GPAA1 GAA1 Homo sapiens (Human) attachment of GPI anchor to protein [GO:0016255]; protein retention in ER lumen [GO:0006621]; protein-containing complex assembly [GO:0065003] centrosome [GO:0005813]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; GPI-anchor transamidase complex [GO:0042765]; membrane [GO:0016020]; mitochondrion [GO:0005739] tubulin binding [GO:0015631] 0.11986 1.0843 GLLSDPVR 9.10722 9.2181 0 0 0 0 9.1372 9.18881 9.12789 9.39913 0 9.14542 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43293 DAPK3_HUMAN Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase) DAPK3 ZIPK Homo sapiens (Human) apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to type II interferon [GO:0071346]; chromatin organization [GO:0006325]; intracellular signal transduction [GO:0035556]; negative regulation of translation [GO:0017148]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of DNA-templated transcription [GO:0006355]; regulation of focal adhesion assembly [GO:0051893]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic nuclear division [GO:0007088]; regulation of myosin II filament organization [GO:0043519]; regulation of smooth muscle contraction [GO:0006940] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605] ATP binding [GO:0005524]; cAMP response element binding protein binding [GO:0008140]; identical protein binding [GO:0042802]; leucine zipper domain binding [GO:0043522]; protein homodimerization activity [GO:0042803]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; small GTPase binding [GO:0031267] 0.92577 -0.96691 FSRLENR 0 0 0 0 0 0 0 0 0 0 0 0 9.70675 0 0 9.26303 0 0 0 8.4508 0 0 0 0 0 0 0 O43294 TGFI1_HUMAN Transforming growth factor beta-1-induced transcript 1 protein (Androgen receptor coactivator 55 kDa protein) (Androgen receptor-associated protein of 55 kDa) (Hydrogen peroxide-inducible clone 5 protein) (Hic-5) TGFB1I1 ARA55 Homo sapiens (Human) cell adhesion [GO:0007155]; cell fate commitment [GO:0045165]; epithelial cell differentiation [GO:0030855]; fat cell differentiation [GO:0045444]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; ubiquitin-dependent SMAD protein catabolic process [GO:0030579]; Wnt signaling pathway [GO:0016055] cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; nuclear matrix [GO:0016363] I-SMAD binding [GO:0070411]; metal ion binding [GO:0046872]; nuclear androgen receptor binding [GO:0050681]; Roundabout binding [GO:0048495]; transcription coactivator activity [GO:0003713] 0.96182 -2.5603 GVPTQAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.47306 O43295 SRGP3_HUMAN SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (Mental disorder-associated GAP) (Rho GTPase-activating protein 14) (WAVE-associated Rac GTPase-activating protein) (WRP) SRGAP3 ARHGAP14 KIAA0411 KIAA1156 MEGAP SRGAP2 Homo sapiens (Human) negative regulation of cell migration [GO:0030336]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829] GTPase activator activity [GO:0005096] 0.897 -0.52506 DSGQAIPLVVESCIRYINLYGLQQQGIFR 0 0 9.54181 0 0 0 0 0 0 11.3592 0 0 0 0 0 0 0 0 0 0 9.94835 0 0 9.61206 0 0 0 O43296 ZN264_HUMAN Zinc finger protein 264 ZNF264 KIAA0412 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.92349 -1.0733 KEDLSQDTCPGDKGKPK 0 0 0 0 0 0 9.708 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43299 AP5Z1_HUMAN AP-5 complex subunit zeta-1 (Adaptor-related protein complex 5 zeta subunit) (Zeta5) AP5Z1 KIAA0415 SPG48 Homo sapiens (Human) double-strand break repair via homologous recombination [GO:0000724]; endosomal transport [GO:0016197]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] AP-5 adaptor complex [GO:0044599]; AP-type membrane coat adaptor complex [GO:0030119]; cytoplasm [GO:0005737]; late endosome [GO:0005770]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.96802 -3.8173 ASGATER 0 0 0 0 0 0 0 0 0 9.95083 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43300 LRRT2_HUMAN Leucine-rich repeat transmembrane neuronal protein 2 (Leucine-rich repeat neuronal 2 protein) LRRTM2 KIAA0416 LRRN2 Homo sapiens (Human) long-term synaptic potentiation [GO:0060291]; negative regulation of receptor internalization [GO:0002091]; positive regulation of synapse assembly [GO:0051965]; regulation of postsynaptic density assembly [GO:0099151]; synapse organization [GO:0050808] excitatory synapse [GO:0060076]; extracellular space [GO:0005615]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; postsynaptic density membrane [GO:0098839]; postsynaptic specialization membrane [GO:0099634]; Schaffer collateral - CA1 synapse [GO:0098685] neurexin family protein binding [GO:0042043] 0.91957 -0.90917 LRSLARNGFAGLIK 0 0 0 0 9.57253 0 0 9.37212 0 9.57016 10.4475 9.35052 0 8.78614 8.93369 8.59216 8.62227 0 8.52344 0 0 0 0 0 0 0 9.97542 O43301 HS12A_HUMAN Heat shock 70 kDa protein 12A HSPA12A KIAA0417 Homo sapiens (Human) cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleus [GO:0005634] ATP binding [GO:0005524] 0.90299 -0.69922 EPECIHVMRRWEGGDPGVSNQK 0 0 0 0 0 0 0 9.63254 0 0 0 0 0 0 11.5152 0 0 0 0 0 9.98698 0 0 0 0 0 0 O43303 CP110_HUMAN Centriolar coiled-coil protein of 110 kDa (Centrosomal protein of 110 kDa) (CP110) (Cep110) CCP110 CEP110 CP110 KIAA0419 Homo sapiens (Human) centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; ciliary basal body organization [GO:0032053]; negative regulation of centriole elongation [GO:1903723]; negative regulation of cilium assembly [GO:1902018]; positive regulation of cilium assembly [GO:0045724]; regulation of cytokinesis [GO:0032465] centriole [GO:0005814]; centrosome [GO:0005813]; cilium [GO:0005929]; cytosol [GO:0005829]; protein-containing complex [GO:0032991] 0.96209 -2.4517 ALDVEARK 0 0 0 0 0 0 0 0 0 0 0 0 0 8.83838 0 0 0 0 0 0 0 0 0 0 10.4255 0 0 O43304 S14L5_HUMAN SEC14-like protein 5 SEC14L5 KIAA0420 Homo sapiens (Human) cytoplasm [GO:0005737] 0.96298 -2.1545 LGAREPGTRASGQLIDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5296 0 11.7724 0 0 0 0 0 0 0 O43306 ADCY6_HUMAN Adenylate cyclase type 6 (EC 4.6.1.1) (ATP pyrophosphate-lyase 6) (Adenylate cyclase type VI) (Adenylyl cyclase 6) (Ca(2+)-inhibitable adenylyl cyclase) ADCY6 KIAA0422 Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; blood vessel diameter maintenance [GO:0097746]; cAMP biosynthetic process [GO:0006171]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to forskolin [GO:1904322]; cellular response to prostaglandin E stimulus [GO:0071380]; cellular response to vasopressin [GO:1904117]; dopamine receptor signaling pathway [GO:0007212]; intracellular signal transduction [GO:0035556]; negative regulation of neuron projection development [GO:0010977]; negative regulation of urine volume [GO:0035811]; renal water homeostasis [GO:0003091] cilium [GO:0005929]; membrane [GO:0016020]; plasma membrane [GO:0005886]; stereocilium [GO:0032420] adenylate cyclase activity [GO:0004016]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; protein kinase C binding [GO:0005080] 0.9643 -2.2799 LQRTRANSMEGLMPR 0 0 11.85 0 10.132 0 0 0 0 0 0 13.1196 0 0 0 0 0 0 0 0 0 0 0 0 11.0419 0 0 O43307 ARHG9_HUMAN Rho guanine nucleotide exchange factor 9 (Collybistin) (PEM-2 homolog) (Rac/Cdc42 guanine nucleotide exchange factor 9) ARHGEF9 ARHDH9 KIAA0424 Homo sapiens (Human) regulation of postsynaptic specialization assembly [GO:0099150]; regulation of small GTPase mediated signal transduction [GO:0051056] cytosol [GO:0005829]; GABA-ergic synapse [GO:0098982]; postsynaptic density [GO:0014069]; postsynaptic specialization [GO:0099572] guanyl-nucleotide exchange factor activity [GO:0005085] 0.96967 -3.0909 AGDVIKVLDASNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.3714 0 O43310 CTIF_HUMAN CBP80/20-dependent translation initiation factor CTIF KIAA0427 Homo sapiens (Human) "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of translational initiation [GO:0006446]" cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471] RNA binding [GO:0003723]; translation activator activity [GO:0008494] 0.88715 -0.35423 GEAGAHR 0 8.09439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4558 0 O43312 MTSS1_HUMAN Protein MTSS 1 (Metastasis suppressor YGL-1) (Metastasis suppressor protein 1) (Missing in metastasis protein) MTSS1 KIAA0429 MIM Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; adherens junction maintenance [GO:0034334]; cell adhesion [GO:0007155]; cellular response to fluid shear stress [GO:0071498]; epithelial cell proliferation involved in renal tubule morphogenesis [GO:2001013]; glomerulus morphogenesis [GO:0072102]; microspike assembly [GO:0030035]; negative regulation of epithelial cell proliferation [GO:0050680]; nephron tubule epithelial cell differentiation [GO:0072160]; plasma membrane organization [GO:0007009]; positive regulation of actin filament bundle assembly [GO:0032233]; renal tubule morphogenesis [GO:0061333]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; endocytic vesicle [GO:0030139]; ruffle [GO:0001726] actin binding [GO:0003779]; actin monomer binding [GO:0003785]; identical protein binding [GO:0042802]; phospholipid binding [GO:0005543]; signaling receptor binding [GO:0005102] 0.92083 -1.1395 NSDISQSYRRMFQAK 0 0 0 0 0 0 9.81275 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43314 VIP2_HUMAN Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 (EC 2.7.4.24) (Diphosphoinositol pentakisphosphate kinase 2) (Histidine acid phosphatase domain-containing protein 1) (InsP6 and PP-IP5 kinase 2) (VIP1 homolog 2) (hsVIP2) PPIP5K2 HISPPD1 KIAA0433 VIP2 Homo sapiens (Human) inositol metabolic process [GO:0006020]; inositol phosphate biosynthetic process [GO:0032958]; inositol phosphate metabolic process [GO:0043647]; phosphorylation [GO:0016310]; sensory perception of sound [GO:0007605] cytosol [GO:0005829] "ATP binding [GO:0005524]; diphosphoinositol-pentakisphosphate kinase activity [GO:0033857]; inositol heptakisphosphate kinase activity [GO:0000829]; inositol hexakisphosphate 1-kinase activity [GO:0052723]; inositol hexakisphosphate 3-kinase activity [GO:0052724]; inositol hexakisphosphate 5-kinase activity [GO:0000832]; inositol hexakisphosphate kinase activity [GO:0000828]; inositol-1,3,4,5,6-pentakisphosphate kinase activity [GO:0000827]" 0.89808 -0.66835 ANGQSYVCDVNGFSFVK 0 0 0 0 0 0 0 0 0 9.74089 9.00054 9.02109 0 0 0 0 0 0 0 0 0 0 0 9.64308 0 0 0 O43316 PAX4_HUMAN Paired box protein Pax-4 PAX4 Homo sapiens (Human) anatomical structure development [GO:0048856]; animal organ morphogenesis [GO:0009887]; cell differentiation [GO:0030154]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleoplasm [GO:0005654] "DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.89838 -0.56805 VSNGCVSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.18304 8.4818 0 8.42366 0 0 0 0 0 0 0 0 0 O43318 M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) MAP3K7 TAK1 Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; anoikis [GO:0043276]; cytosolic pattern recognition receptor signaling pathway [GO:0002753]; Fc-epsilon receptor signaling pathway [GO:0038095]; histone H3 acetylation [GO:0043966]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; I-kappaB phosphorylation [GO:0007252]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17A-mediated signaling pathway [GO:0038173]; JNK cascade [GO:0007254]; MAPK cascade [GO:0000165]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; p38MAPK cascade [GO:0038066]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of macroautophagy [GO:0016239]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell cytokine production [GO:0002726]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; transforming growth factor beta receptor signaling pathway [GO:0007179] ATAC complex [GO:0140672]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; nucleus [GO:0005634]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; identical protein binding [GO:0042802]; linear polyubiquitin binding [GO:1990450]; magnesium ion binding [GO:0000287]; MAP kinase activity [GO:0004707]; MAP kinase kinase kinase activity [GO:0004709]; MAP kinase kinase kinase kinase activity [GO:0008349]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; receptor tyrosine kinase binding [GO:0030971]; scaffold protein binding [GO:0097110] 0.89013 -0.48702 DPSQRPSMEEIVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.72755 0 0 0 0 0 10.4756 9.74012 0 0 0 O43320 FGF16_HUMAN Fibroblast growth factor 16 (FGF-16) FGF16 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell differentiation [GO:0030154]; cell-cell signaling [GO:0007267]; fibroblast growth factor receptor signaling pathway [GO:0008543]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of gene expression [GO:0010628]; positive regulation of protein phosphorylation [GO:0001934]; response to temperature stimulus [GO:0009266]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615] fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083] 0.80384 0.23872 GELYGSK 0 0 0 0 0 0 0 0 0 0 0 0 9.59113 0 0 0 0 0 0 0 0 0 10.2192 0 0 0 0 O43325 LYRM1_HUMAN LYR motif-containing protein 1 LYRM1 Homo sapiens (Human) midbody [GO:0030496]; nucleoplasm [GO:0005654] 0.78335 0.25423 IEIGLHYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.85866 0 O43347 MSI1H_HUMAN RNA-binding protein Musashi homolog 1 (Musashi-1) MSI1 Homo sapiens (Human) central nervous system development [GO:0007417]; epithelial cell differentiation [GO:0030855]; nervous system development [GO:0007399]; regulation of translation [GO:0006417]; response to hormone [GO:0009725] cytoplasm [GO:0005737]; nucleus [GO:0005634]; polysome [GO:0005844] identical protein binding [GO:0042802]; mRNA binding [GO:0003729]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723] 0.89742 -0.53021 VLAQSRHELDSK 9.32816 9.33691 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43361 ZN749_HUMAN Zinc finger protein 749 ZNF749 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.95893 -1.8316 FFRYRCTLSR 10.7325 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43364 HXA2_HUMAN Homeobox protein Hox-A2 (Homeobox protein Hox-1K) HOXA2 HOX1K Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; brain segmentation [GO:0035284]; cell fate determination [GO:0001709]; cellular response to retinoic acid [GO:0071300]; dorsal/ventral pattern formation [GO:0009953]; embryonic viscerocranium morphogenesis [GO:0048703]; middle ear morphogenesis [GO:0042474]; motor neuron axon guidance [GO:0008045]; muscle structure development [GO:0061061]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of osteoblast differentiation [GO:0045668]; osteoblast development [GO:0002076]; pharyngeal system development [GO:0060037]; positive regulation of transcription by RNA polymerase II [GO:0045944]; rhombomere 2 development [GO:0021568]; rhombomere 3 morphogenesis [GO:0021658]; segment specification [GO:0007379] chromatin [GO:0000785]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.8835 -0.27636 QTQCKENQNSEGK 0 0 0 0 0 0 0 0 0 0 0 8.70553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43374 RASL2_HUMAN Ras GTPase-activating protein 4 (Calcium-promoted Ras inactivator) (Ras p21 protein activator 4) (RasGAP-activating-like protein 2) RASA4 CAPRI GAPL KIAA0538 Homo sapiens (Human) cellular response to calcium ion [GO:0071277]; intracellular signal transduction [GO:0035556]; negative regulation of GTPase activity [GO:0034260]; negative regulation of Ras protein signal transduction [GO:0046580] cytosol [GO:0005829]; plasma membrane [GO:0005886] GTPase activator activity [GO:0005096]; metal ion binding [GO:0046872]; phospholipid binding [GO:0005543] 0.96914 -4.4805 AKRSSLYIR 0 0 0 0 0 0 0 0 0 8.46066 0 0 0 0 10.0203 0 0 8.98305 0 0 0 0 0 0 0 0 9.70248 O43390 HNRPR_HUMAN Heterogeneous nuclear ribonucleoprotein R (hnRNP R) HNRNPR HNRPR Homo sapiens (Human) "mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]" catalytic step 2 spliceosome [GO:0071013]; endoplasmic reticulum [GO:0005783]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681] mRNA binding [GO:0003729]; RNA binding [GO:0003723] 0 8.0738 AGPIWDLR 0 0 0 0 0 0 0 0 0 0 0 0 0 8.76059 8.82235 0 0 0 0 8.75178 8.91433 0 0 0 0 0 9.44559 O43395 PRPF3_HUMAN U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) (hPrp3) (U4/U6 snRNP 90 kDa protein) PRPF3 HPRP3 PRP3 Homo sapiens (Human) "mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal tri-snRNP complex assembly [GO:0000244]" Cajal body [GO:0015030]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540] identical protein binding [GO:0042802]; RNA binding [GO:0003723] 0.82543 0.21431 LFEAVEEGR 0 9.26313 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43405 COCH_HUMAN Cochlin (COCH-5B2) COCH COCH5B2 UNQ257/PRO294 Homo sapiens (Human) regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605] collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576] collagen binding [GO:0005518] 0.84861 0.15559 VYSLPGR 0 0 0 0 0 0 0 0 0 9.45843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43414 ERI3_HUMAN ERI1 exoribonuclease 3 (EC 3.1.-.-) (Prion interactor 1) (Prion protein-interacting protein) ERI3 PINT1 PRNPIP PRNPIP1 Homo sapiens (Human) "exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]" 3'-5'-RNA exonuclease activity [GO:0000175]; metal ion binding [GO:0046872]; RNA binding [GO:0003723] 0.96813 -2.8752 FSSYLLSRAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2515 0 0 0 0 0 0 0 0 0 0 0 0 O43423 AN32C_HUMAN Putative uncharacterized protein ANP32CP (Acidic leucine-rich nuclear phosphoprotein 32 family member C) (Phosphoprotein 32-related protein 1) (Tumorigenic protein pp32r1) ANP32CP PP32R1 Homo sapiens (Human) nucleocytoplasmic transport [GO:0006913]; regulation of apoptotic process [GO:0042981] perinuclear region of cytoplasm [GO:0048471] histone binding [GO:0042393] 0.83549 0.1908 LLLQLTYLDSCYWDHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.70726 9.53465 0 0 10.9239 0 0 O43424 GRID2_HUMAN "Glutamate receptor ionotropic, delta-2 (GluD2) (GluR delta-2 subunit)" GRID2 GLURD2 Homo sapiens (Human) "cerebellar granule cell differentiation [GO:0021707]; excitatory postsynaptic potential [GO:0060079]; excitatory synapse assembly [GO:1904861]; glutamate receptor signaling pathway [GO:0007215]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of long-term synaptic depression [GO:1900454]; positive regulation of synapse assembly [GO:0051965]; prepulse inhibition [GO:0060134]; protein localization [GO:0008104]; regulation of neuron apoptotic process [GO:0043523]; regulation of neuron projection development [GO:0010975]; regulation of postsynaptic density assembly [GO:0099151]; synaptic transmission, glutamatergic [GO:0035249]" dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; ionotropic glutamate receptor complex [GO:0008328]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; synapse [GO:0045202] glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; PDZ domain binding [GO:0030165]; scaffold protein binding [GO:0097110]; transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315] 0.95499 -1.5218 GIQEFLDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.83327 0 0 0 0 0 0 0 0 0 0 0 O43426 SYNJ1_HUMAN "Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1)" SYNJ1 KIAA0910 Homo sapiens (Human) brain development [GO:0007420]; inositol phosphate metabolic process [GO:0043647]; learning [GO:0007612]; membrane organization [GO:0061024]; neurotransmitter transport [GO:0006836]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; phosphatidylinositol metabolic process [GO:0046488]; positive regulation of endosome organization [GO:1904980]; positive regulation of gliogenesis [GO:0014015]; positive regulation of receptor-mediated endocytosis [GO:0048260]; response to cytokine [GO:0034097]; response to retinoic acid [GO:0032526]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle priming [GO:0016082]; synaptic vesicle transport [GO:0048489]; synaptic vesicle uncoating [GO:0016191] clathrin coat of coated pit [GO:0030132]; cytosol [GO:0005829]; membrane coat [GO:0030117]; microtubule [GO:0005874]; parallel fiber to Purkinje cell synapse [GO:0098688]; perinuclear region of cytoplasm [GO:0048471]; presynapse [GO:0098793]; synaptic membrane [GO:0097060]; terminal bouton [GO:0043195]; vesicle membrane [GO:0012506] "EH domain binding [GO:1990175]; inositol-1,4,5-trisphosphate 5-phosphatase activity [GO:0052658]; phosphatidylinositol phosphate 4-phosphatase activity [GO:0034596]; phosphatidylinositol phosphate 5-phosphatase activity [GO:0034595]; phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity [GO:0052629]; phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity [GO:0043813]; phosphatidylinositol-3-phosphate phosphatase activity [GO:0004438]; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity [GO:0004439]; phosphatidylinositol-4-phosphate phosphatase activity [GO:0043812]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]" 0.95466 -1.6147 EVIAVQGPPDGTVLVSIK 12.7578 0 0 0 10.1233 9.43912 0 0 0 11.209 0 0 0 0 0 13.2298 0 9.03028 0 8.3293 0 0 0 0 0 0 0 O43427 FIBP_HUMAN Acidic fibroblast growth factor intracellular-binding protein (aFGF intracellular-binding protein) (FGF-1 intracellular-binding protein) FIBP Homo sapiens (Human) fibroblast growth factor receptor signaling pathway [GO:0008543]; platelet aggregation [GO:0070527] endomembrane system [GO:0012505]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleus [GO:0005634] fibroblast growth factor binding [GO:0017134] 0.93281 -1.2782 DLDDISTK 0 0 0 0 0 0 0 0 8.9865 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.33829 0 O43432 IF4G3_HUMAN Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII) EIF4G3 Homo sapiens (Human) positive regulation of translation [GO:0045727]; regulation of translational initiation [GO:0006446]; spermatid development [GO:0007286]; translational initiation [GO:0006413] cytosol [GO:0005829]; eukaryotic translation initiation factor 4F complex [GO:0016281]; intracellular non-membrane-bounded organelle [GO:0043232] "mRNA binding [GO:0003729]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]; translation factor activity, RNA binding [GO:0008135]; translation initiation factor activity [GO:0003743]" 0.91418 -0.82038 GSSGGAK 8.69143 0 0 8.05463 9.49651 0 0 0 0 0 8.54647 0 8.1641 8.49693 0 0 9.5112 0 0 0 0 11.4976 9.21079 10.5103 0 9.96982 9.22567 O43435 TBX1_HUMAN T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T-box protein) TBX1 Homo sapiens (Human) angiogenesis [GO:0001525]; anterior/posterior pattern specification [GO:0009952]; aorta morphogenesis [GO:0035909]; artery morphogenesis [GO:0048844]; blood vessel development [GO:0001568]; blood vessel morphogenesis [GO:0048514]; cell fate specification [GO:0001708]; cell population proliferation [GO:0008283]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to retinoic acid [GO:0071300]; cochlea morphogenesis [GO:0090103]; coronary artery morphogenesis [GO:0060982]; determination of left/right symmetry [GO:0007368]; ear morphogenesis [GO:0042471]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic viscerocranium morphogenesis [GO:0048703]; enamel mineralization [GO:0070166]; epithelial cell differentiation [GO:0030855]; face morphogenesis [GO:0060325]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; inner ear morphogenesis [GO:0042472]; lymph vessel development [GO:0001945]; mesenchymal cell apoptotic process [GO:0097152]; mesoderm development [GO:0007498]; middle ear morphogenesis [GO:0042474]; muscle cell fate commitment [GO:0042693]; muscle organ development [GO:0007517]; muscle organ morphogenesis [GO:0048644]; muscle tissue morphogenesis [GO:0060415]; negative regulation of cell differentiation [GO:0045596]; negative regulation of mesenchymal cell apoptotic process [GO:2001054]; neural crest cell migration [GO:0001755]; odontogenesis of dentin-containing tooth [GO:0042475]; outer ear morphogenesis [GO:0042473]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; parathyroid gland development [GO:0060017]; pattern specification process [GO:0007389]; pharyngeal system development [GO:0060037]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of tongue muscle cell differentiation [GO:2001037]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of animal organ morphogenesis [GO:2000027]; regulation of transcription by RNA polymerase II [GO:0006357]; retinoic acid receptor signaling pathway [GO:0048384]; semicircular canal morphogenesis [GO:0048752]; sensory perception of sound [GO:0007605]; social behavior [GO:0035176]; soft palate development [GO:0060023]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; tongue morphogenesis [GO:0043587]; vagus nerve morphogenesis [GO:0021644] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.95112 -1.4199 EVKAETSR 0 0 9.93696 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43439 MTG8R_HUMAN Protein CBFA2T2 (ETO homologous on chromosome 20) (MTG8-like protein) (MTG8-related protein 1) (Myeloid translocation-related protein 1) (p85) CBFA2T2 EHT MTGR1 Homo sapiens (Human) intestinal epithelial cell differentiation [GO:0060575]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of neuron projection development [GO:0010977]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of neuron projection development [GO:0010976] nucleus [GO:0005634] metal ion binding [GO:0046872]; transcription corepressor activity [GO:0003714] 0.92499 -0.97681 EPNKMLEHREVR 0 0 0 0 0 0 10.8057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43447 PPIH_HUMAN Peptidyl-prolyl cis-trans isomerase H (PPIase H) (EC 5.2.1.8) (Rotamase H) (Small nuclear ribonucleoprotein particle-specific cyclophilin H) (CypH) (U-snRNP-associated cyclophilin SnuCyp-20) (USA-CYP) PPIH CYP20 CYPH Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein-containing complex assembly [GO:0065003]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U4/U6 snRNP [GO:0071001]; U4/U6 x U5 tri-snRNP complex [GO:0046540] cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; ribonucleoprotein complex binding [GO:0043021] 0.85803 0.10116 TAENFRQFCTGEFR 0 0 0 9.10413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43448 KCAB3_HUMAN Voltage-gated potassium channel subunit beta-3 (K(+) channel subunit beta-3) (Kv-beta-3) KCNAB3 KCNA3B Homo sapiens (Human) potassium ion transport [GO:0006813]; regulation of potassium ion transmembrane transport [GO:1901379] cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076] aldo-keto reductase (NADP) activity [GO:0004033]; potassium channel regulator activity [GO:0015459]; transmembrane transporter binding [GO:0044325]; voltage-gated potassium channel activity [GO:0005249] 0.96169 -2.0731 DKVQSEDGKK 0 0 0 0 0 0 11.4447 0 0 0 0 9.14139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43451 MGA_HUMAN "Maltase-glucoamylase (Alpha-1,4-glucosidase) (EC 3.2.1.20)" MGAM MGA MGAML Homo sapiens (Human) dextrin catabolic process [GO:1901027]; maltose catabolic process [GO:0000025]; starch catabolic process [GO:0005983] apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821] "alpha-1,4-glucosidase activity [GO:0004558]; amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]" 0.96295 -2.1289 DQPPGYKK 0 0 10.2765 0 0 0 10.3057 10.1529 10.3242 0 9.34172 0 0 0 0 0 0 0 0 0 0 0 9.46536 0 0 0 0 O43463 SUV91_HUMAN Histone-lysine N-methyltransferase SUV39H1 (EC 2.1.1.355) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Lysine N-methyltransferase 1A) (Position-effect variegation 3-9 homolog) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) SUV39H1 KMT1A SUV39H Homo sapiens (Human) cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cellular response to glucose starvation [GO:0042149]; cellular response to hypoxia [GO:0071456]; chromatin organization [GO:0006325]; circadian rhythm [GO:0007623]; DNA damage response [GO:0006974]; energy homeostasis [GO:0097009]; histone lysine methylation [GO:0034968]; negative regulation of cell cycle [GO:0045786]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of histone methylation [GO:0031062]; rDNA heterochromatin formation [GO:0000183]; regulation of transcription by glucose [GO:0046015]; rRNA processing [GO:0006364] "chromatin silencing complex [GO:0005677]; chromosome, centromeric region [GO:0000775]; condensed nuclear chromosome [GO:0000794]; eNoSc complex [GO:0061773]; heterochromatin [GO:0000792]; nuclear lamina [GO:0005652]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; rDNA heterochromatin [GO:0033553]" chromatin binding [GO:0003682]; histone H3K9 methyltransferase activity [GO:0046974]; histone H3K9 trimethyltransferase activity [GO:0140949]; histone methyltransferase activity [GO:0042054]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; transcription cis-regulatory region binding [GO:0000976]; zinc ion binding [GO:0008270] 0.22878 0.86593 HLDPSLANYLVQKAK 0 15.6661 8.98319 11.632 11.63 11.9811 16.2018 16.2626 0 16.6208 16.3875 0 13.1708 0 0 14.8655 15.0491 14.938 12.9135 0 12.8105 9.97671 13.0454 12.9767 0 0 15.0832 O43464 HTRA2_HUMAN "Serine protease HTRA2, mitochondrial (EC 3.4.21.108) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine protease 25) (Serine proteinase OMI)" HTRA2 OMI PRSS25 Homo sapiens (Human) adult walking behavior [GO:0007628]; aging [GO:0007568]; cellular response to growth factor stimulus [GO:0071363]; cellular response to heat [GO:0034605]; cellular response to interferon-beta [GO:0035458]; cellular response to oxidative stress [GO:0034599]; cellular response to retinoic acid [GO:0071300]; ceramide metabolic process [GO:0006672]; execution phase of apoptosis [GO:0097194]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitochondrion organization [GO:0007005]; negative regulation of cell cycle [GO:0045786]; negative regulation of mitophagy in response to mitochondrial depolarization [GO:1904924]; negative regulation of neuron death [GO:1901215]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; neuron development [GO:0048666]; pentacyclic triterpenoid metabolic process [GO:0019742]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of mitochondrion organization [GO:0010822]; positive regulation of protein targeting to mitochondrion [GO:1903955]; programmed cell death [GO:0012501]; protein autoprocessing [GO:0016540]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of multicellular organism growth [GO:0040014]; response to herbicide [GO:0009635] CD40 receptor complex [GO:0035631]; chromatin [GO:0000785]; cytoplasmic side of plasma membrane [GO:0009898]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; mitochondrial intermembrane space [GO:0005758]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; serine-type endopeptidase complex [GO:1905370] identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; unfolded protein binding [GO:0051082] 0.84783 0.12688 ALLTSGTSDPR 10.4597 0 0 0 0 0 0 0 0 0 10.8404 0 0 0 0 0 0 0 0 0 0 9.32186 0 10.1311 0 0 0 O43491 E41L2_HUMAN Band 4.1-like protein 2 (Erythrocyte membrane protein band 4.1-like 2) (Generally expressed protein 4.1) (4.1G) EPB41L2 Homo sapiens (Human) actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein localization to cell cortex [GO:1904778] cell cortex [GO:0005938]; cell junction [GO:0030054]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; spectrin [GO:0008091] actin binding [GO:0003779]; PH domain binding [GO:0042731]; spectrin binding [GO:0030507]; structural molecule activity [GO:0005198] 0.95131 -1.4315 GGISETRIEK 0 11.3759 0 0 0 0 0 10.1746 14.7122 0 0 12.4116 0 0 16.0021 0 0 0 0 0 0 0 0 0 0 0 9.70691 O43493 TGON2_HUMAN Trans-Golgi network integral membrane protein 2 (Trans-Golgi network glycoprotein 46) (TGN38 homolog) (hTGN46) (Trans-Golgi network glycoprotein 48) (hTGN48) (Trans-Golgi network glycoprotein 51) (hTGN51) (Trans-Golgi network protein 2) TGOLN2 TGN46 TGN51 Homo sapiens (Human) clathrin-coated endocytic vesicle membrane [GO:0030669]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; transport vesicle [GO:0030133] 0.92412 -1.0432 SGAEKQTPK 0 9.06234 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43497 CAC1G_HUMAN Voltage-dependent T-type calcium channel subunit alpha-1G (Cav3.1c) (NBR13) (Voltage-gated calcium channel subunit alpha Cav3.1) CACNA1G KIAA1123 Homo sapiens (Human) AV node cell action potential [GO:0086016]; AV node cell to bundle of His cell signaling [GO:0086027]; calcium ion import [GO:0070509]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; cardiac muscle cell action potential involved in contraction [GO:0086002]; chemical synaptic transmission [GO:0007268]; membrane depolarization during AV node cell action potential [GO:0086045]; membrane depolarization during SA node cell action potential [GO:0086046]; regulation of atrial cardiac muscle cell membrane depolarization [GO:0060371]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of membrane potential [GO:0042391]; regulation of monoatomic ion transmembrane transport [GO:0034765]; response to nickel cation [GO:0010045]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell signaling [GO:0086018]; sinoatrial node development [GO:0003163] cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; synapse [GO:0045202]; voltage-gated calcium channel complex [GO:0005891] high voltage-gated calcium channel activity [GO:0008331]; low voltage-gated calcium channel activity [GO:0008332]; scaffold protein binding [GO:0097110]; voltage-gated calcium channel activity involved in AV node cell action potential [GO:0086056]; voltage-gated calcium channel activity involved SA node cell action potential [GO:0086059] 0.96927 -4.5615 CRQHQEEEEAR 0 0 0 10.7493 0 9.13681 0 0 0 0 9.65864 0 0 0 0 0 0 0 0 0 0 0 0 0 12.2923 0 0 O43502 RA51C_HUMAN DNA repair protein RAD51 homolog 3 (R51H3) (RAD51 homolog C) (RAD51-like protein 2) RAD51C RAD51L2 Homo sapiens (Human) DNA recombination [GO:0006310]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; female meiosis sister chromatid cohesion [GO:0007066]; male meiosis I [GO:0007141]; meiotic DNA recombinase assembly [GO:0000707]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; reciprocal meiotic recombination [GO:0007131]; sister chromatid cohesion [GO:0007062]; spermatogenesis [GO:0007283]; telomere maintenance via recombination [GO:0000722] cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; Rad51B-Rad51C-Rad51D-XRCC2 complex [GO:0033063]; Rad51C-XRCC3 complex [GO:0033065]; replication fork [GO:0005657] ATP binding [GO:0005524]; ATP-dependent DNA damage sensor activity [GO:0140664]; crossover junction DNA endonuclease activity [GO:0008821]; DNA binding [GO:0003677] 0.82292 0.21545 LIFHWDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4337 0 0 0 0 0 0 0 O43506 ADA20_HUMAN Disintegrin and metalloproteinase domain-containing protein 20 (ADAM 20) (EC 3.4.24.-) ADAM20 Homo sapiens (Human) male gonad development [GO:0008584]; proteolysis [GO:0006508]; single fertilization [GO:0007338] external side of plasma membrane [GO:0009897]; plasma membrane [GO:0005886]; sperm head plasma membrane [GO:1990913] metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237] 0.76 0.29562 GYGGSADSGPPPK 0 0 0 0 0 0 0 0 0 9.54338 9.62857 9.69464 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43508 TNF12_HUMAN "Tumor necrosis factor ligand superfamily member 12 (APO3 ligand) (TNF-related weak inducer of apoptosis) (TWEAK) [Cleaved into: Tumor necrosis factor ligand superfamily member 12, membrane form; Tumor necrosis factor ligand superfamily member 12, secreted form]" TNFSF12 APO3L DR3LG UNQ181/PRO207 Homo sapiens (Human) angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cell differentiation [GO:0030154]; endothelial cell migration [GO:0043542]; extrinsic apoptotic signaling pathway [GO:0097191]; immune response [GO:0006955]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of protein catabolic process [GO:0045732]; signal transduction [GO:0007165] extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] cytokine activity [GO:0005125]; receptor ligand activity [GO:0048018]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164] 0.84613 0.17326 TLPWAHLK 9.45432 0 9.49047 9.74576 0 9.48663 0 9.43704 9.52333 10.0546 9.89723 10.2194 0 0 0 0 0 0 0 0 0 0 0 9.67354 0 0 0 O43511 S26A4_HUMAN Pendrin (Sodium-independent chloride/iodide transporter) (Solute carrier family 26 member 4) SLC26A4 PDS Homo sapiens (Human) inorganic anion transport [GO:0015698]; iodide transport [GO:0015705]; monoatomic ion transport [GO:0006811]; regulation of pH [GO:0006885]; regulation of protein localization [GO:0032880]; sensory perception of sound [GO:0007605]; sulfate transport [GO:0008272] apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886] bicarbonate transmembrane transporter activity [GO:0015106]; chloride transmembrane transporter activity [GO:0015108]; chloride:bicarbonate antiporter activity [GO:0140900]; iodide transmembrane transporter activity [GO:0015111]; oxalate transmembrane transporter activity [GO:0019531]; secondary active sulfate transmembrane transporter activity [GO:0008271]; sulfate transmembrane transporter activity [GO:0015116] 0.94651 -1.3461 GMFMQLCDIPRLWRQNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.9572 0 0 O43513 MED7_HUMAN Mediator of RNA polymerase II transcription subunit 7 (hMED7) (Activator-recruited cofactor 34 kDa component) (ARC34) (Cofactor required for Sp1 transcriptional activation subunit 9) (CRSP complex subunit 9) (Mediator complex subunit 7) (RNA polymerase transcriptional regulation mediator subunit 7 homolog) (Transcriptional coactivator CRSP33) MED7 ARC34 CRSP9 Homo sapiens (Human) positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; protein ubiquitination [GO:0016567]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA polymerase II preinitiation complex assembly [GO:0051123]; somatic stem cell population maintenance [GO:0035019]; transcription initiation at RNA polymerase II promoter [GO:0006367] core mediator complex [GO:0070847]; mediator complex [GO:0016592]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667]; ubiquitin ligase complex [GO:0000151] transcription coactivator activity [GO:0003713]; ubiquitin protein ligase activity [GO:0061630] 0.87202 0.027331 DQIIEKDAALCVLIDEMNERP 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16.1314 0 0 0 0 0 0 0 0 0 0 0 0 O43516 WIPF1_HUMAN WAS/WASL-interacting protein family member 1 (Protein PRPL-2) (Wiskott-Aldrich syndrome protein-interacting protein) (WASP-interacting protein) WIPF1 WASPIP WIP Homo sapiens (Human) actin filament-based movement [GO:0030048]; actin polymerization or depolymerization [GO:0008154]; protein-containing complex assembly [GO:0065003]; response to other organism [GO:0051707] actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; ruffle [GO:0001726] actin binding [GO:0003779]; profilin binding [GO:0005522]; protein folding chaperone [GO:0044183]; SH3 domain binding [GO:0017124] 0.87173 0.064999 LPQRNLSLSSSTPPLPSPGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.3922 0 0 0 0 O43520 AT8B1_HUMAN Phospholipid-transporting ATPase IC (EC 7.6.2.1) (ATPase class I type 8B member 1) (Familial intrahepatic cholestasis type 1) (P4-ATPase flippase complex alpha subunit ATP8B1) ATP8B1 ATPIC FIC1 PFIC Homo sapiens (Human) apical protein localization [GO:0045176]; bile acid and bile salt transport [GO:0015721]; bile acid metabolic process [GO:0008206]; Golgi organization [GO:0007030]; inner ear receptor cell development [GO:0060119]; monoatomic ion transmembrane transport [GO:0034220]; negative regulation of DNA-templated transcription [GO:0045892]; phospholipid translocation [GO:0045332]; regulation of chloride transport [GO:2001225]; regulation of microvillus assembly [GO:0032534]; regulation of plasma membrane organization [GO:1903729]; sensory perception of sound [GO:0007605]; vestibulocochlear nerve formation [GO:0021650]; xenobiotic transmembrane transport [GO:0006855] apical plasma membrane [GO:0016324]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; phospholipid-translocating ATPase complex [GO:1990531]; plasma membrane [GO:0005886]; stereocilium [GO:0032420]; trans-Golgi network [GO:0005802] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled intramembrane lipid transporter activity [GO:0140326]; cardiolipin binding [GO:1901612]; magnesium ion binding [GO:0000287]; phosphatidylcholine flippase activity [GO:0140345]; phosphatidylcholine floppase activity [GO:0090554]; phosphatidylserine flippase activity [GO:0140346]; phosphatidylserine floppase activity [GO:0090556] 0.96926 -3.1599 DTPAKAR 0 0 0 8.7416 0 0 0 0 0 11.1696 0 9.41838 0 0 0 0 0 0 0 8.96174 0 0 0 0 10.3689 10.1399 0 O43524 FOXO3_HUMAN Forkhead box protein O3 (AF6q21 protein) (Forkhead in rhabdomyosarcoma-like 1) FOXO3 FKHRL1 FOXO3A Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to glucose starvation [GO:0042149]; cellular response to oxidative stress [GO:0034599]; mitochondrial transcription [GO:0006390]; negative regulation of cell migration [GO:0030336]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of autophagy [GO:0010508]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of muscle atrophy [GO:0014737]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; response to fatty acid [GO:0070542]; response to starvation [GO:0042594]; tumor necrosis factor-mediated signaling pathway [GO:0033209] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; RNA polymerase II transcription repressor complex [GO:0090571] "beta-catenin binding [GO:0008013]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; mitochondrial transcription factor activity [GO:0034246]; protein kinase binding [GO:0019901]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]" 0.92431 -1.0667 FMRVQNEGTGK 0 8.21864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43525 KCNQ3_HUMAN Potassium voltage-gated channel subfamily KQT member 3 (KQT-like 3) (Potassium channel subunit alpha KvLQT3) (Voltage-gated potassium channel subunit Kv7.3) KCNQ3 Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; establishment of localization in cell [GO:0051649]; membrane hyperpolarization [GO:0060081]; potassium ion transmembrane transport [GO:0071805]; regulation of monoatomic ion transmembrane transport [GO:0034765] axon initial segment [GO:0043194]; cell surface [GO:0009986]; node of Ranvier [GO:0033268]; plasma membrane [GO:0005886]; synapse [GO:0045202]; voltage-gated potassium channel complex [GO:0008076] calmodulin binding [GO:0005516]; voltage-gated potassium channel activity [GO:0005249] 0.9689 -3.318 DDYVFGPNGGSSWMREK 0 0 9.67377 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.271 0 0 0 0 O43526 KCNQ2_HUMAN Potassium voltage-gated channel subfamily KQT member 2 (KQT-like 2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (Voltage-gated potassium channel subunit Kv7.2) KCNQ2 Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; nervous system development [GO:0007399]; potassium ion transmembrane transport [GO:0071805]; regulation of monoatomic ion transmembrane transport [GO:0034765] axon initial segment [GO:0043194]; node of Ranvier [GO:0033268]; plasma membrane [GO:0005886]; synapse [GO:0045202]; voltage-gated potassium channel complex [GO:0008076] ankyrin binding [GO:0030506]; calmodulin binding [GO:0005516]; voltage-gated potassium channel activity [GO:0005249] 0.96885 -3.886 AVCVMRFLVSKR 8.86542 8.64137 0 0 0 0 0 0 0 0 0 0 0 11.1874 0 0 10.7091 0 0 0 0 0 0 0 9.88556 10.4812 0 O43541 SMAD6_HUMAN Mothers against decapentaplegic homolog 6 (MAD homolog 6) (Mothers against DPP homolog 6) (SMAD family member 6) (SMAD 6) (Smad6) (hSMAD6) SMAD6 MADH6 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; BMP signaling pathway [GO:0030509]; cell differentiation [GO:0030154]; cell-substrate adhesion [GO:0031589]; coronary vasculature development [GO:0060976]; fat cell differentiation [GO:0045444]; immune response [GO:0006955]; mitral valve morphogenesis [GO:0003183]; negative regulation of apoptotic process [GO:0043066]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of SMAD protein complex assembly [GO:0010991]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of miRNA transcription [GO:1902895]; pulmonary valve morphogenesis [GO:0003184]; regulation of transcription by RNA polymerase II [GO:0006357]; response to estrogen [GO:0043627]; response to laminar fluid shear stress [GO:0034616]; response to lipopolysaccharide [GO:0032496]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ureteric bud development [GO:0001657]; ventricular septum development [GO:0003281]; zygotic specification of dorsal/ventral axis [GO:0007352] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; heteromeric SMAD protein complex [GO:0071144]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] chromatin binding [GO:0003682]; co-SMAD binding [GO:0070410]; I-SMAD binding [GO:0070411]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; R-SMAD binding [GO:0070412]; transcription cis-regulatory region binding [GO:0000976]; transcription regulator inhibitor activity [GO:0140416]; type I activin receptor binding [GO:0070698]; type I transforming growth factor beta receptor binding [GO:0034713]; ubiquitin protein ligase binding [GO:0031625] 0.64641 0.39623 GAQGAGR 0 0 0 0 0 0 0 0 0 10.2952 0 0 0 0 0 0 0 8.92914 0 0 0 8.95079 9.16656 0 0 8.46418 13.08 O43548 TGM5_HUMAN Protein-glutamine gamma-glutamyltransferase 5 (EC 2.3.2.13) (Transglutaminase X) (TG(X)) (TGX) (TGase X) (Transglutaminase-5) (TGase-5) TGM5 TGMX Homo sapiens (Human) epidermis development [GO:0008544]; peptide cross-linking [GO:0018149]; protein modification process [GO:0036211] cytoplasm [GO:0005737]; plasma membrane [GO:0005886] metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810] 0.9678 -2.8808 ISALGEEKSSPEK 0 0 0 0 0 0 10.4324 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43556 SGCE_HUMAN Epsilon-sarcoglycan (Epsilon-SG) SGCE ESG UNQ433/PRO840 Homo sapiens (Human) cell-matrix adhesion [GO:0007160]; muscle organ development [GO:0007517] cytoskeleton [GO:0005856]; dendrite membrane [GO:0032590]; dystrophin-associated glycoprotein complex [GO:0016010]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; sarcoglycan complex [GO:0016012]; sarcolemma [GO:0042383] 0.82526 0.21354 CSQEMEPVITCDK 0 0 0 0 0 0 0 0 0 0 0 10.1988 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43566 RGS14_HUMAN Regulator of G-protein signaling 14 (RGS14) RGS14 Homo sapiens (Human) cell division [GO:0051301]; chromosome segregation [GO:0007059]; G protein-coupled receptor signaling pathway [GO:0007186]; learning [GO:0007612]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; mitotic cell cycle [GO:0000278]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of synaptic plasticity [GO:0031914]; nucleocytoplasmic transport [GO:0006913]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neurogenesis [GO:0050769]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to oxidative stress [GO:0006979]; spindle organization [GO:0007051]; visual learning [GO:0008542]; zygote asymmetric cell division [GO:0010070] centrosome [GO:0005813]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; microtubule [GO:0005874]; nuclear body [GO:0016604]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic density [GO:0014069]; spindle [GO:0005819]; spindle pole [GO:0000922] G-protein alpha-subunit binding [GO:0001965]; GDP-dissociation inhibitor activity [GO:0005092]; GTPase activating protein binding [GO:0032794]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; microtubule binding [GO:0008017]; protein kinase binding [GO:0019901]; signaling receptor complex adaptor activity [GO:0030159] 0.90555 -0.72446 FVKSPLYR 0 0 17.0819 12.6439 0 13.574 0 0 0 0 0 9.83031 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43586 PPIP1_HUMAN Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP) PSTPIP1 CD2BP1 Homo sapiens (Human) actin filament polymerization [GO:0030041]; cell adhesion [GO:0007155]; endocytosis [GO:0006897]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; signal transduction [GO:0007165] actin filament [GO:0005884]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lamellipodium [GO:0030027]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; uropod [GO:0001931] actin filament binding [GO:0051015]; identical protein binding [GO:0042802] 0.92403 -1.0346 DFTAHTGYEVLLQR 9.86071 0 0 0 9.67113 0 10.7712 0 0 0 0 9.4748 0 0 0 0 0 0 0 0 0 10.5638 0 0 0 0 0 O43593 HAIR_HUMAN Lysine-specific demethylase hairless (EC 1.14.11.65) ([histone H3]-dimethyl-L-lysine(9) demethylase hairless) HR Homo sapiens (Human) histone H3-K9 demethylation [GO:0033169]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654] chromatin DNA binding [GO:0031490]; histone H3K9 demethylase activity [GO:0032454]; histone H3K9me/H3K9me2 demethylase activity [GO:0140683]; metal ion binding [GO:0046872]; transcription coregulator activity [GO:0003712] 0.78466 0.25336 VAVGTLQEAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5522 0 0 9.75363 0 0 0 O43598 DNPH1_HUMAN 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 (EC 3.2.2.-) (c-Myc-responsive protein RCL) DNPH1 C6orf108 RCL Homo sapiens (Human) deoxyribonucleoside monophosphate catabolic process [GO:0009159]; epithelial cell differentiation [GO:0030855]; nucleoside metabolic process [GO:0009116]; positive regulation of cell growth [GO:0030307]; purine nucleotide catabolic process [GO:0006195] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634] deoxyribonucleoside 5'-monophosphate N-glycosidase activity [GO:0070694]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803] 0.72267 0.35712 FGTVLTEHVAAAELGAR 17.2247 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.19463 0 0 0 0 0 0 0 0 0 9.6167 10.5724 O43602 DCX_HUMAN Neuronal migration protein doublecortin (Doublin) (Lissencephalin-X) (Lis-X) DCX DBCN LISX Homo sapiens (Human) axoneme assembly [GO:0035082]; central nervous system development [GO:0007417]; intracellular signal transduction [GO:0035556]; nervous system development [GO:0007399]; neuron migration [GO:0001764]; retina development in camera-type eye [GO:0060041] cytoskeleton [GO:0005856]; cytosol [GO:0005829]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; neuron projection [GO:0043005] microtubule binding [GO:0008017]; protein kinase binding [GO:0019901] 0.96256 -2.0854 DFVRPKLVTIIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5611 0 0 O43615 TIM44_HUMAN Mitochondrial import inner membrane translocase subunit TIM44 TIMM44 MIMT44 TIM44 Homo sapiens (Human) intracellular protein transport [GO:0006886]; protein import into mitochondrial matrix [GO:0030150]; protein targeting to mitochondrion [GO:0006626] fibrillar center [GO:0001650]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; TIM23 mitochondrial import inner membrane translocase complex [GO:0005744] ATP binding [GO:0005524]; protein-folding chaperone binding [GO:0051087] 0.95007 -1.4045 ESLHEVSKSDLGR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1552 0 0 0 0 0 0 0 0 9.75442 0 0 0 0 O43633 CHM2A_HUMAN Charged multivesicular body protein 2a (Chromatin-modifying protein 2a) (CHMP2a) (Putative breast adenocarcinoma marker BC-2) (Vacuolar protein sorting-associated protein 2-1) (Vps2-1) (hVps2-1) CHMP2A BC2 CHMP2 Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; endosome transport via multivesicular body sorting pathway [GO:0032509]; ESCRT III complex disassembly [GO:1904903]; establishment of protein localization [GO:0045184]; exit from mitosis [GO:0010458]; late endosome to lysosome transport [GO:1902774]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; membrane fission [GO:0090148]; membrane invagination [GO:0010324]; midbody abscission [GO:0061952]; mitotic metaphase plate congression [GO:0007080]; multivesicular body assembly [GO:0036258]; multivesicular body sorting pathway [GO:0071985]; multivesicular body-lysosome fusion [GO:0061763]; negative regulation of cell death [GO:0060548]; negative regulation of centriole elongation [GO:1903723]; nuclear membrane reassembly [GO:0031468]; nucleus organization [GO:0006997]; plasma membrane repair [GO:0001778]; positive regulation of exosomal secretion [GO:1903543]; protein homooligomerization [GO:0051260]; protein polymerization [GO:0051258]; protein transport [GO:0015031]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic spindle assembly [GO:1901673]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; vesicle fusion with vacuole [GO:0051469]; viral budding from plasma membrane [GO:0046761]; viral budding via host ESCRT complex [GO:0039702]; viral release from host cell [GO:0019076] amphisome membrane [GO:1904930]; autophagosome membrane [GO:0000421]; cytosol [GO:0005829]; ESCRT III complex [GO:0000815]; extracellular exosome [GO:0070062]; kinetochore [GO:0000776]; kinetochore microtubule [GO:0005828]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane coat [GO:0030117]; midbody [GO:0030496]; multivesicular body [GO:0005771]; multivesicular body membrane [GO:0032585]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; plasma membrane [GO:0005886] phosphatidylcholine binding [GO:0031210]; protein domain specific binding [GO:0019904] 0.77236 0.26684 ANIQAVSLK 0 0 11.4977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43639 NCK2_HUMAN Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta) NCK2 GRB4 Homo sapiens (Human) actin filament organization [GO:0007015]; cell migration [GO:0016477]; dendritic spine development [GO:0060996]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; immunological synapse formation [GO:0001771]; lamellipodium assembly [GO:0030032]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:1903912]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990441]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation in response to endoplasmic reticulum stress [GO:0036493]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; T cell activation [GO:0042110] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; postsynaptic density [GO:0014069]; vesicle membrane [GO:0012506] cytoskeletal anchor activity [GO:0008093]; phosphotyrosine residue binding [GO:0001784]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; signaling adaptor activity [GO:0035591]; signaling receptor complex adaptor activity [GO:0030159] 0.89011 -0.47592 KNERLWLLDDSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4452 0 0 0 0 0 10.1649 0 0 0 0 O43663 PRC1_HUMAN Protein regulator of cytokinesis 1 PRC1 Homo sapiens (Human) cell division [GO:0051301]; microtubule cytoskeleton organization [GO:0000226]; mitotic spindle elongation [GO:0000022]; mitotic spindle midzone assembly [GO:0051256]; positive regulation of cell population proliferation [GO:0008284]; regulation of cytokinesis [GO:0032465] chromosome [GO:0005694]; contractile ring [GO:0070938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; mitotic spindle midzone [GO:1990023]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; spindle [GO:0005819]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922] identical protein binding [GO:0042802]; kinesin binding [GO:0019894]; microtubule binding [GO:0008017]; protein kinase binding [GO:0019901] 0.96326 -2.1532 ELFEGVQK 0 0 12.7329 0 0 0 0 0 0 0 0 0 0 9.83719 0 0 0 0 0 0 0 0 0 0 0 0 0 O43665 RGS10_HUMAN Regulator of G-protein signaling 10 (RGS10) RGS10 Homo sapiens (Human) G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277] cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202] G-protein alpha-subunit binding [GO:0001965]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924] 0.9511 -1.4001 HKRTEEEEEDLPDAQTAAK 0 0 0 0 0 0 0 0 0 0 0 0 10.6319 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43674 NDUB5_HUMAN "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (Complex I-SGDH) (CI-SGDH) (NADH-ubiquinone oxidoreductase SGDH subunit)" NDUFB5 Homo sapiens (Human) "aerobic respiration [GO:0009060]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]" mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex I [GO:0005747]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] NADH dehydrogenase (ubiquinone) activity [GO:0008137] 0.87614 -0.001689 LGFGGFLTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.75909 O43678 NDUA2_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (Complex I-B8) (CI-B8) (NADH-ubiquinone oxidoreductase B8 subunit) NDUFA2 Homo sapiens (Human) "aerobic respiration [GO:0009060]; blastocyst hatching [GO:0001835]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]" mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex I [GO:0005747] NADH dehydrogenase (ubiquinone) activity [GO:0008137] 0.96284 -2.1272 ALENVLSGKA 0 0 10.1018 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6305 0 0 0 0 0 0 0 0 0 0 O43680 TCF21_HUMAN Transcription factor 21 (TCF-21) (Capsulin) (Class A basic helix-loop-helix protein 23) (bHLHa23) (Epicardin) (Podocyte-expressed 1) (Pod-1) TCF21 BHLHA23 POD1 Homo sapiens (Human) branching involved in ureteric bud morphogenesis [GO:0001658]; branchiomeric skeletal muscle development [GO:0014707]; bronchiole development [GO:0060435]; developmental process [GO:0032502]; diaphragm development [GO:0060539]; embryonic digestive tract morphogenesis [GO:0048557]; epithelial cell differentiation [GO:0030855]; gland development [GO:0048732]; glomerulus development [GO:0032835]; kidney development [GO:0001822]; lung alveolus development [GO:0048286]; lung morphogenesis [GO:0060425]; lung vasculature development [GO:0060426]; metanephric glomerular capillary formation [GO:0072277]; metanephric mesenchymal cell differentiation [GO:0072162]; morphogenesis of a branching structure [GO:0001763]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; reproductive structure development [GO:0048608]; respiratory system development [GO:0060541]; roof of mouth development [GO:0060021]; Sertoli cell differentiation [GO:0060008]; sex determination [GO:0007530]; spleen development [GO:0048536]; ureteric bud development [GO:0001657]; vasculature development [GO:0001944] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "bHLH transcription factor binding [GO:0043425]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; E-box binding [GO:0070888]; histone deacetylase binding [GO:0042826]; nuclear androgen receptor binding [GO:0050681]; protein dimerization activity [GO:0046983]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.91993 -1.1426 GRGGLGK 0 0 0 9.90956 10.0991 10.0428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43681 GET3_HUMAN "ATPase GET3 (EC 3.6.-.-) (Arsenical pump-driving ATPase) (Arsenite-stimulated ATPase) (Guided entry of tail-anchored proteins factor 3, ATPase) (Transmembrane domain recognition complex 40 kDa ATPase subunit) (hARSA-I) (hASNA-I)" GET3 ARSA ASNA1 TRC40 Homo sapiens (Human) post-translational protein targeting to endoplasmic reticulum membrane [GO:0006620]; protein insertion into ER membrane [GO:0045048]; tail-anchored membrane protein insertion into ER membrane [GO:0071816] cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; GET complex [GO:0043529]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] arsenite transmembrane transporter activity [GO:0015105]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; membrane insertase activity [GO:0032977]; metal ion binding [GO:0046872] 0.45092 0.64108 ESVLIISTDPAHNISDAFDQK 0 0 0 0 0 0 0 0 0 10.3277 0 0 0 0 0 0 0 0 0 9.28977 9.2107 0 9.46903 0 10.9875 10.449 9.87381 O43704 ST1B1_HUMAN Sulfotransferase 1B1 (ST1B1) (EC 2.8.2.1) (Sulfotransferase 1B2) (Sulfotransferase family cytosolic 1B member 1) (Thyroid hormone sulfotransferase) SULT1B1 ST1B2 SULT1B2 Homo sapiens (Human) 3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; biogenic amine metabolic process [GO:0006576]; epithelial cell differentiation [GO:0030855]; ethanol catabolic process [GO:0006068]; flavonoid metabolic process [GO:0009812]; phenol-containing compound metabolic process [GO:0018958]; sulfation [GO:0051923]; thyroid hormone metabolic process [GO:0042403]; xenobiotic metabolic process [GO:0006805] cytoplasm [GO:0005737]; cytosol [GO:0005829] aryl sulfotransferase activity [GO:0004062]; sulfotransferase activity [GO:0008146] 0.79395 0.24445 NYFTVAQNEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3904 0 O43707 ACTN4_HUMAN Alpha-actinin-4 (Non-muscle alpha-actinin 4) ACTN4 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; muscle cell development [GO:0055001]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; positive regulation of cell migration [GO:0030335]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of sodium:proton antiporter activity [GO:0032417]; protein transport [GO:0015031]; regulation of apoptotic process [GO:0042981]; regulation of nucleic acid-templated transcription [GO:1903506]; response to hypoxia [GO:0001666]; retinoic acid receptor signaling pathway [GO:0048384]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; vesicle transport along actin filament [GO:0030050] actin cytoskeleton [GO:0015629]; cell junction [GO:0030054]; cell projection [GO:0042995]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; pseudopodium [GO:0031143]; ribonucleoprotein complex [GO:1990904]; stress fiber [GO:0001725]; Z disc [GO:0030018] actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; chromatin DNA binding [GO:0031490]; integrin binding [GO:0005178]; nuclear receptor binding [GO:0016922]; nuclear receptor coactivator activity [GO:0030374]; nuclear retinoic acid receptor binding [GO:0042974]; nucleoside binding [GO:0001882]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]; transmembrane transporter binding [GO:0044325]; ubiquitin protein ligase binding [GO:0031625] 0 48.39 ALDFIASK 9.88169 9.16538 0 0 12.0807 0 9.25342 9.29937 9.47515 10.3328 11.4196 10.6815 11.9599 11.1835 11.2374 12.242 12.1112 11.3926 11.2625 12.2279 11.8596 11.3161 11.4619 11.8597 13.3274 13.0325 12.8354 O43736 ITM2A_HUMAN Integral membrane protein 2A (Protein E25) ITM2A UNQ603/PRO1189 Homo sapiens (Human) negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; plasma cell differentiation [GO:0002317] Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886] amyloid-beta binding [GO:0001540] 0.95216 -1.4466 ELRVATQEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.251 O43739 CYH3_HUMAN "Cytohesin-3 (ARF nucleotide-binding site opener 3) (Protein ARNO3) (General receptor of phosphoinositides 1) (Grp1) (PH, SEC7 and coiled-coil domain-containing protein 3)" CYTH3 ARNO3 GRP1 PSCD3 Homo sapiens (Human) establishment of epithelial cell polarity [GO:0090162]; Golgi vesicle transport [GO:0048193]; positive regulation of cell adhesion [GO:0045785]; regulation of ARF protein signal transduction [GO:0032012] adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; ruffle [GO:0001726] "guanyl-nucleotide exchange factor activity [GO:0005085]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]" 0.5861 0.46855 ISAPSPEEK 0 9.90111 0 0 0 0 0 0 0 0 0 0 0 0 0 8.9892 0 0 0 0 0 0 0 0 0 0 9.60879 O43747 AP1G1_HUMAN AP-1 complex subunit gamma-1 (Adaptor protein complex AP-1 subunit gamma-1) (Adaptor-related protein complex 1 subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain) (Gamma1-adaptin) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) AP1G1 ADTG CLAPG1 Homo sapiens (Human) basolateral protein secretion [GO:0110010]; endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886]; melanosome assembly [GO:1903232]; melanosome organization [GO:0032438]; platelet dense granule organization [GO:0060155]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; vesicle-mediated transport [GO:0016192] AP-1 adaptor complex [GO:0030121]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; early endosome [GO:0005769]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; trans-Golgi network membrane [GO:0032588] clathrin adaptor activity [GO:0035615]; GTP-dependent protein binding [GO:0030742]; kinesin binding [GO:0019894]; small GTPase binding [GO:0031267] 0.62828 0.40172 ELLYFLDSCEPEFK 0 0 0 0 0 0 0 0 0 0 0 16.8382 0 9.26845 0 0 0 0 0 0 0 0 0 0 0 0 0 O43760 SNG2_HUMAN Synaptogyrin-2 (Cellugyrin) SYNGR2 UNQ352/PRO615 Homo sapiens (Human) regulated exocytosis [GO:0045055]; synaptic vesicle membrane organization [GO:0048499] extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; synaptic vesicle membrane [GO:0030672] 0 4.3968 DVLVGADSVR 0 0 0 0 0 0 0 0 0 9.6022 10.3801 10.1039 0 0 0 0 0 0 0 0 0 0 0 0 9.35425 0 0 O43763 TLX2_HUMAN T-cell leukemia homeobox protein 2 (Homeobox protein Hox-11L1) (Neural crest homeobox protein) TLX2 HOX11L1 NCX Homo sapiens (Human) animal organ development [GO:0048513]; enteric nervous system development [GO:0048484]; mesoderm formation [GO:0001707]; negative regulation of dendrite morphogenesis [GO:0050774]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.91577 -0.76333 MTDAQVKTWFQNR 0 0 0 0 0 0 0 0 0 0 9.49817 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43765 SGTA_HUMAN Small glutamine-rich tetratricopeptide repeat-containing protein alpha (Alpha-SGT) (Vpu-binding protein) (UBP) SGTA SGT SGT1 Homo sapiens (Human) negative regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903070]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; positive regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903071]; post-translational protein targeting to endoplasmic reticulum membrane [GO:0006620]; tail-anchored membrane protein insertion into ER membrane [GO:0071816]; ubiquitin-dependent ERAD pathway [GO:0030433] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; TRC complex [GO:0072380] BAT3 complex binding [GO:1904288]; identical protein binding [GO:0042802]; molecular adaptor activity [GO:0060090]; protein self-association [GO:0043621] 0.82045 0.21943 MGLALSSLNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2737 O43776 SYNC_HUMAN "Asparagine--tRNA ligase, cytoplasmic (EC 6.1.1.22) (Asparaginyl-tRNA synthetase) (AsnRS) (Asparaginyl-tRNA synthetase 1)" NARS1 NARS NRS Homo sapiens (Human) asparaginyl-tRNA aminoacylation [GO:0006421]; cell migration [GO:0016477]; cerebral cortex development [GO:0021987]; tRNA aminoacylation for protein translation [GO:0006418] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062] asparagine-tRNA ligase activity [GO:0004816]; ATP binding [GO:0005524]; CCR3 chemokine receptor binding [GO:0031728]; nucleic acid binding [GO:0003676]; protein dimerization activity [GO:0046983] 0.8504 0.16569 LMTDTINEPILLCR 0 0 0 0 0 8.96645 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43795 MYO1B_HUMAN Unconventional myosin-Ib (MYH-1c) (Myosin I alpha) (MMI-alpha) (MMIa) MYO1B Homo sapiens (Human) actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; actin filament-based movement [GO:0030048]; post-Golgi vesicle-mediated transport [GO:0006892]; vesicle transport along actin filament [GO:0030050] actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical part of cell [GO:0045177]; brush border [GO:0005903]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; myosin complex [GO:0016459]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982] "actin filament binding [GO:0051015]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; microfilament motor activity [GO:0000146]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]" 0.96993 -5.0343 IFHLWRCK 0 0 0 0 0 11.636 0 0 0 0 0 0 0 0 0 0 0 11.5716 0 0 0 0 0 0 0 10.9511 0 O43805 SSNA1_HUMAN Microtubule nucleation factor SSNA1 (Nuclear autoantigen of 14 kDa) (Sjoegren syndrome nuclear autoantigen 1) SSNA1 NA14 Homo sapiens (Human) axon arborization [GO:0140060]; axon extension [GO:0048675]; axonogenesis [GO:0007409]; cell cycle [GO:0007049]; cell division [GO:0051301]; ciliary receptor clustering involved in smoothened signaling pathway [GO:0060830]; intraciliary transport [GO:0042073]; microtubule cytoskeleton organization [GO:0000226]; microtubule nucleation [GO:0007020] axon [GO:0030424]; axoneme [GO:0005930]; centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytosol [GO:0005829]; midbody [GO:0030496]; motile cilium [GO:0031514]; nucleus [GO:0005634]; supramolecular fiber [GO:0099512] identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protein self-association [GO:0043621] 0.88619 -0.33968 IASRNEFDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.41121 0 0 9.8308 0 0 0 0 0 0 0 0 O43808 PM34_HUMAN Peroxisomal membrane protein PMP34 (34 kDa peroxisomal membrane protein) (Solute carrier family 25 member 17) SLC25A17 PMP34 Homo sapiens (Human) ATP transport [GO:0015867]; fatty acid alpha-oxidation [GO:0001561]; fatty acid beta-oxidation [GO:0006635]; fatty acid transport [GO:0015908] cytosol [GO:0005829]; membrane [GO:0016020]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777] adenine nucleotide transmembrane transporter activity [GO:0000295]; ADP transmembrane transporter activity [GO:0015217]; AMP transmembrane transporter activity [GO:0080122]; antiporter activity [GO:0015297]; ATP transmembrane transporter activity [GO:0005347]; coenzyme A transmembrane transporter activity [GO:0015228]; FAD transmembrane transporter activity [GO:0015230]; FMN transmembrane transporter activity [GO:0044610]; NAD transmembrane transporter activity [GO:0051724]; protein-folding chaperone binding [GO:0051087] 0.88328 -0.26519 ALWVKGQHSTTGK 0 0 0 0 0 0 0 0 0 11.0947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43813 LANC1_HUMAN Glutathione S-transferase LANCL1 (EC 2.5.1.18) (40 kDa erythrocyte membrane protein) (p40) (LanC-like protein 1) LANCL1 GPR69A Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; cellular detoxification [GO:1990748]; G protein-coupled receptor signaling pathway [GO:0007186]; peptide modification [GO:0031179] cytoplasm [GO:0005737]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; low-density lipoprotein particle receptor binding [GO:0050750]; SH3 domain binding [GO:0017124]; zinc ion binding [GO:0008270] 0.79492 0.24461 AFPNPYADYNKSLAEGYFDAAGR 10.9167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43815 STRN_HUMAN Striatin STRN Homo sapiens (Human) bicellular tight junction assembly [GO:0070830]; dendrite development [GO:0016358]; locomotory behavior [GO:0007626]; negative regulation of cell population proliferation [GO:0008285]; Wnt signaling pathway [GO:0016055] bicellular tight junction [GO:0005923]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; FAR/SIN/STRIPAK complex [GO:0090443]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211] armadillo repeat domain binding [GO:0070016]; calmodulin binding [GO:0005516]; nuclear estrogen receptor binding [GO:0030331]; protein phosphatase 2A binding [GO:0051721]; protein-containing complex binding [GO:0044877] 0.96397 -2.4197 DTKEALKEFDFLVTSEEGDNESR 0 0 10.3854 0 0 0 0 0 0 0 0 0 0 0 9.50224 0 0 0 0 8.96258 0 10.0957 0 0 0 0 0 O43818 U3IP2_HUMAN U3 small nucleolar RNA-interacting protein 2 (RRP9 homolog) (U3 small nucleolar ribonucleoprotein-associated 55 kDa protein) (U3 snoRNP-associated 55 kDa protein) (U3-55K) RRP9 RNU3IP2 U355K Homo sapiens (Human) ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364] box C/D RNP complex [GO:0031428]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040] RNA binding [GO:0003723]; snoRNA binding [GO:0030515]; U3 snoRNA binding [GO:0034511] 0.95757 -1.6631 EDVLEQRGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.01856 0 0 0 O43823 AKAP8_HUMAN A-kinase anchor protein 8 (AKAP-8) (A-kinase anchor protein 95 kDa) (AKAP 95) AKAP8 AKAP95 Homo sapiens (Human) cell cycle G2/M phase transition [GO:0044839]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to prostaglandin E stimulus [GO:0071380]; innate immune response [GO:0045087]; mitotic cell cycle [GO:0000278]; mitotic chromosome condensation [GO:0007076]; negative regulation of tumor necrosis factor production [GO:0032720]; protein transport [GO:0015031]; signal transduction [GO:0007165] condensed chromosome [GO:0000793]; female pronucleus [GO:0001939]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] double-stranded DNA binding [GO:0003690]; histone deacetylase binding [GO:0042826]; NF-kappaB binding [GO:0051059]; protein kinase A regulatory subunit binding [GO:0034237]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270] 0.92375 -1.029 HLHSVDHNHNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.1875 0 0 9.35385 O43829 ZBT14_HUMAN Zinc finger and BTB domain-containing protein 14 (Zinc finger protein 161 homolog) (Zfp-161) (Zinc finger protein 478) (Zinc finger protein 5 homolog) (ZF5) (Zfp-5) (hZF5) ZBTB14 ZFP161 ZNF478 Homo sapiens (Human) cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]; heart valve development [GO:0003170]; kidney development [GO:0001822]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122] aggresome [GO:0016235]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]" 0.95477 -1.5193 FLDKLCSQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.1843 0 0 O43847 NRDC_HUMAN Nardilysin (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C) (Nardilysin convertase) NRDC NRD1 Homo sapiens (Human) negative regulation of cold-induced thermogenesis [GO:0120163]; positive regulation of axonogenesis [GO:0050772]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of myelination [GO:0031643]; proteolysis [GO:0006508]; regulation of endopeptidase activity [GO:0052548] cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739] epidermal growth factor binding [GO:0048408]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222] 0.56453 0.48628 ALNKGDANSEVTVYYQSGTR 0 0 0 0 9.12959 0 12.3969 0 0 0 0 0 9.7138 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43852 CALU_HUMAN Calumenin (Crocalbin) (IEF SSP 9302) CALU Homo sapiens (Human) endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; melanosome [GO:0042470]; membrane [GO:0016020]; sarcoplasmic reticulum lumen [GO:0033018] calcium ion binding [GO:0005509] 0.42201 0.66554 TFDQLTPEESK 8.81721 8.95428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43854 EDIL3_HUMAN EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) EDIL3 DEL1 Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular vesicle [GO:1903561] calcium ion binding [GO:0005509]; integrin binding [GO:0005178] 0.9626 -2.5071 HIRILPWSWYGRITLR 0 0 0 0 0 0 11.8632 0 0 0 0 0 0 10.7649 0 0 0 0 0 9.81226 0 0 9.74772 9.95641 0 0 0 O43861 ATP9B_HUMAN Probable phospholipid-transporting ATPase IIB (EC 7.6.2.1) (ATPase class II type 9B) ATP9B ATPIIB NEO1L HUSSY-20 Homo sapiens (Human) "endocytosis [GO:0006897]; phospholipid translocation [GO:0045332]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]" endosome [GO:0005768]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled intramembrane lipid transporter activity [GO:0140326]; magnesium ion binding [GO:0000287] 0.6982 0.3749 AAYYSAAGPRPGADR 0 0 0 0 9.55882 0 0 0 0 0 0 0 10.4469 10.6604 0 10.7912 11.303 0 0 0 0 0 0 0 0 0 0 O43865 SAHH2_HUMAN S-adenosylhomocysteine hydrolase-like protein 1 (DC-expressed AHCY-like molecule) (IP(3)Rs binding protein released with IP(3)) (IRBIT) (Putative adenosylhomocysteinase 2) (S-adenosyl-L-homocysteine hydrolase 2) (AdoHcyase 2) AHCYL1 DCAL IRBIT XPVKONA Homo sapiens (Human) angiotensin-activated signaling pathway [GO:0038166]; apoptotic process [GO:0006915]; epithelial fluid transport [GO:0042045]; mitochondrion-endoplasmic reticulum membrane tethering [GO:1990456]; mRNA polyadenylation [GO:0006378]; one-carbon metabolic process [GO:0006730]; positive regulation of sodium ion transport [GO:0010765]; protein export from nucleus [GO:0006611]; regulation of monoatomic anion transport [GO:0044070]; regulation of monoatomic ion transmembrane transporter activity [GO:0032412]; regulation of mRNA 3'-end processing [GO:0031440]; response to calcium ion [GO:0051592]; S-adenosylmethionine cycle [GO:0033353] apical plasma membrane [GO:0016324]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; mitochondria-associated endoplasmic reticulum membrane [GO:0044233] identical protein binding [GO:0042802]; RNA binding [GO:0003723] 0.89854 -0.61916 KRAQGEKPLAGAK 11.0473 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43866 CD5L_HUMAN CD5 antigen-like (Apoptosis inhibitor expressed by macrophages) (hAIM) (CT-2) (IgM-associated peptide) (SP-alpha) CD5L API6 UNQ203/PRO229 Homo sapiens (Human) apoptotic process [GO:0006915]; cellular defense response [GO:0006968]; immune system process [GO:0002376]; inflammatory response [GO:0006954]; positive regulation of complement-dependent cytotoxicity [GO:1903661]; regulation of complement activation [GO:0030449]; zymogen activation [GO:0031638] blood microparticle [GO:0072562]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] scavenger receptor activity [GO:0005044]; serine-type endopeptidase activity [GO:0004252] 0.96225 -2.5088 CEGRVEVEQK 0 11.557 0 0 0 0 0 0 0 11.8554 12.0705 12.1833 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.067 O43895 XPP2_HUMAN Xaa-Pro aminopeptidase 2 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Membrane-bound aminopeptidase P) (Membrane-bound APP) (Membrane-bound AmP) (mAmP) (X-Pro aminopeptidase 2) XPNPEP2 Homo sapiens (Human) proteolysis [GO:0006508] extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886] aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006] 0.88434 -0.14316 KAAVWTDSRYWTQAER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.71562 0 0 0 0 0 0 0 0 0 O43896 KIF1C_HUMAN Kinesin-like protein KIF1C KIF1C KIAA0706 Homo sapiens (Human) "anterograde neuronal dense core vesicle transport [GO:1990048]; cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]; retrograde neuronal dense core vesicle transport [GO:1990049]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; vesicle-mediated transport [GO:0016192]" axon [GO:0030424]; axon cytoplasm [GO:1904115]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; kinesin complex [GO:0005871]; microtubule [GO:0005874] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; cytoskeletal motor activity [GO:0003774]; microtubule binding [GO:0008017]; plus-end-directed microtubule motor activity [GO:0008574]; RNA binding [GO:0003723] 0.95209 -1.4505 LQGLQGSGGRGGGLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5483 0 0 0 0 0 0 0 0 0 0 0 O43897 TLL1_HUMAN Tolloid-like protein 1 (EC 3.4.24.-) TLL1 TLL Homo sapiens (Human) cell differentiation [GO:0030154]; collagen fibril organization [GO:0030199]; dorsal/ventral pattern formation [GO:0009953]; protein processing [GO:0016485]; skeletal system development [GO:0001501] extracellular region [GO:0005576]; extracellular space [GO:0005615] calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270] 0.72712 0.34901 ENIQPGQEYNFLK 0 0 0 0 0 0 9.59006 0 0 0 0 0 0 0 9.50869 0 0 0 0 8.83573 0 0 0 0 0 0 0 O43900 PRIC3_HUMAN Prickle planar cell polarity protein 3 (LIM domain only protein 6) (LMO-6) (Prickle-like protein 3) (Pk3) (Triple LIM domain protein 6) PRICKLE3 LMO6 Homo sapiens (Human) cell projection organization [GO:0030030] mitochondrion [GO:0005739]; plasma membrane [GO:0005886] zinc ion binding [GO:0008270] 0.95947 -1.8826 DKNCIVA 0 0 9.88713 0 0 0 0 0 8.81996 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43908 NKG2F_HUMAN NKG2-F type II integral membrane protein (NK cell receptor F) (NKG2-F-activating NK receptor) KLRC4 NKG2F Homo sapiens (Human) positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; stimulatory C-type lectin receptor signaling pathway [GO:0002223] membrane [GO:0016020] 0.94004 -1.3261 GLLPPPEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.938 0 0 0 0 0 O43909 EXTL3_HUMAN Exostosin-like 3 (EC 2.4.1.223) (EXT-related protein 1) (Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Hereditary multiple exostoses gene isolog) (Multiple exostosis-like protein 3) (Putative tumor suppressor protein EXTL3) EXTL3 EXTL1L EXTR1 KIAA0519 Homo sapiens (Human) heparan sulfate proteoglycan biosynthetic process [GO:0015012]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of inflammatory response [GO:0050728]; negative regulation of inflammatory response to wounding [GO:0106015]; positive regulation of cell growth [GO:0030307]; positive regulation of detection of glucose [GO:2000972]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; protein glycosylation [GO:0006486] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; plasma membrane [GO:0005886] glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity [GO:0001888]; glycosyltransferase activity [GO:0016757]; magnesium ion binding [GO:0000287]; protein-hormone receptor activity [GO:0016500] 0.92724 -1.1868 IESLRSSLQEAR 0 0 0 0 0 0 0 9.31619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.70006 O43913 ORC5_HUMAN Origin recognition complex subunit 5 ORC5 ORC5L Homo sapiens (Human) DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; regulation of DNA replication [GO:0006275] "chromatin [GO:0000785]; chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; nuclear origin of replication recognition complex [GO:0005664]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; origin recognition complex [GO:0000808]" ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; nucleotide binding [GO:0000166] 0.9395 -1.3197 GLSAHTHVELPYYSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5355 0 10.3141 O43920 NDUS5_HUMAN NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 (Complex I-15 kDa) (CI-15 kDa) (NADH-ubiquinone oxidoreductase 15 kDa subunit) NDUFS5 Homo sapiens (Human) "aerobic respiration [GO:0009060]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]" mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial respiratory chain complex I [GO:0005747]; mitochondrion [GO:0005739] NADH dehydrogenase (ubiquinone) activity [GO:0008137] 0.86315 0.080649 FGLNIDRWLTIQSGEQPYK 0 0 0 9.7431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O43929 ORC4_HUMAN Origin recognition complex subunit 4 ORC4 ORC4L Homo sapiens (Human) DNA replication initiation [GO:0006270]; polar body extrusion after meiotic divisions [GO:0040038]; protein polymerization [GO:0051258] "chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; nuclear origin of replication recognition complex [GO:0005664]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; origin recognition complex [GO:0000808]" ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; nucleotide binding [GO:0000166] 0.95316 -1.486 GSGKTMLINHALK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.91234 0 0 0 0 0 0 0 0 0 O60218 AK1BA_HUMAN Aldo-keto reductase family 1 member B10 (EC 1.1.1.300) (EC 1.1.1.54) (ARL-1) (Aldose reductase-like) (Aldose reductase-related protein) (ARP) (hARP) (Small intestine reductase) (SI reductase) AKR1B10 AKR1B11 Homo sapiens (Human) cellular detoxification of aldehyde [GO:0110095]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; farnesol catabolic process [GO:0016488]; retinoid metabolic process [GO:0001523] cytosol [GO:0005829]; extracellular region [GO:0005576]; lysosome [GO:0005764]; mitochondrion [GO:0005739] alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; allyl-alcohol dehydrogenase activity [GO:0047655]; geranylgeranyl reductase activity [GO:0045550]; indanol dehydrogenase activity [GO:0047718]; NADP-retinol dehydrogenase activity [GO:0052650]; retinal dehydrogenase activity [GO:0001758] 0.117 1.1186 ALGVSNFSHFQIEK 12.6932 12.656 0 0 0 0 12.3247 0 11.9957 11.9782 0 12.854 0 0 0 0 0 8.86827 0 0 0 0 0 0 0 8.91552 8.40131 O60225 SSX5_HUMAN Protein SSX5 SSX5 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] 0.96415 -2.2074 AFDDIAKYFSEK 8.84627 0 0 0 0 0 0 9.05154 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60229 KALRN_HUMAN Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain) KALRN DUET DUO HAPIP TRAD Homo sapiens (Human) axon guidance [GO:0007411]; ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; nervous system development [GO:0007399]; protein phosphorylation [GO:0006468]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; vesicle-mediated transport [GO:0016192] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; nucleoplasm [GO:0005654]; postsynaptic density [GO:0014069] ATP binding [GO:0005524]; guanyl-nucleotide exchange factor activity [GO:0005085]; metal ion binding [GO:0046872]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96907 -6.8217 CIHKATRK 12.034 0 0 0 0 0 0 0 0 11.8329 8.58481 11.9829 0 9.1079 0 0 0 0 11.429 0 9.55821 0 9.64762 0 0 0 0 O60231 DHX16_HUMAN Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.4.13) (ATP-dependent RNA helicase #3) (DEAH-box protein 16) DHX16 DBP2 DDX16 KIAA0577 PRP2 Homo sapiens (Human) "antiviral innate immune response [GO:0140374]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]" cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2-type precatalytic spliceosome [GO:0071005] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; helicase activity [GO:0004386]; molecular adaptor activity [GO:0060090]; pattern recognition receptor activity [GO:0038187]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; ubiquitin binding [GO:0043130] 0.96735 -2.7997 AKELEDPHAK 9.53557 0 0 0 0 0 0 0 0 0 0 10.8555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60237 MYPT2_HUMAN Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase-targeting subunit 2) (Myosin phosphatase target subunit 2) PPP1R12B MYPT2 Homo sapiens (Human) regulation of muscle contraction [GO:0006937]; signal transduction [GO:0007165] A band [GO:0031672]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; Z disc [GO:0030018] enzyme activator activity [GO:0008047]; enzyme inhibitor activity [GO:0004857]; phosphatase regulator activity [GO:0019208]; protein kinase binding [GO:0019901] 0.8782 0.0035938 GTGINFWTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.52329 0 0 0 0 O60239 3BP5_HUMAN SH3 domain-binding protein 5 (SH3BP-5) (SH3 domain-binding protein that preferentially associates with BTK) SH3BP5 SAB Homo sapiens (Human) intracellular signal transduction [GO:0035556]; negative regulation of protein tyrosine kinase activity [GO:0061099]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654] guanyl-nucleotide exchange factor activity [GO:0005085]; protein kinase inhibitor activity [GO:0004860]; SH3 domain binding [GO:0017124] 0.96297 -2.4423 AEGAENKTSDK 0 0 0 0 0 0 0 0 0 10.3517 0 0 0 0 0 0 0 0 0 0 0 10.4312 0 0 0 0 0 O60240 PLIN1_HUMAN Perilipin-1 (Lipid droplet-associated protein) PLIN1 PERI PLIN Homo sapiens (Human) cellular response to cold [GO:0070417]; lipid catabolic process [GO:0016042]; lipid metabolic process [GO:0006629] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; lipid droplet [GO:0005811] lipid binding [GO:0008289] 0.8819 -0.096359 GLDHLEEK 0 0 0 0 0 0 0 0 0 0 0 0 0 12.3054 0 0 0 0 11.1635 0 0 0 0 0 0 0 0 O60242 AGRB3_HUMAN Adhesion G protein-coupled receptor B3 (Brain-specific angiogenesis inhibitor 3) ADGRB3 BAI3 KIAA0550 Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of synapse structure [GO:0099558]; motor learning [GO:0061743]; myoblast fusion [GO:0007520]; negative regulation of angiogenesis [GO:0016525]; neuron remodeling [GO:0016322]; positive regulation of synapse assembly [GO:0051965]; regulation of dendrite morphogenesis [GO:0048814]; regulation of synapse maturation [GO:0090128]; regulation of synapse pruning [GO:1905806] cerebellar climbing fiber to Purkinje cell synapse [GO:0150053]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density membrane [GO:0098839]; synaptic cleft [GO:0043083] G protein-coupled receptor activity [GO:0004930]; GTPase activator activity [GO:0005096] 0.9648 -2.6985 NVTDTFK 0 0 0 0 9.71058 10.3512 0 0 10.3749 0 0 0 0 9.35935 0 10.267 0 0 0 0 8.15081 0 0 0 0 0 8.58676 O60243 H6ST1_HUMAN Heparan-sulfate 6-O-sulfotransferase 1 (HS6ST-1) (EC 2.8.2.-) HS6ST1 HS6ST Homo sapiens (Human) "angiogenesis [GO:0001525]; heparan sulfate proteoglycan biosynthetic process, enzymatic modification [GO:0015015]; labyrinthine layer blood vessel development [GO:0060716]; lung alveolus development [GO:0048286]; neuron development [GO:0048666]" Golgi membrane [GO:0000139]; plasma membrane [GO:0005886] heparan sulfate 6-O-sulfotransferase activity [GO:0017095]; sulfotransferase activity [GO:0008146] 0.96461 -2.6923 AKEALPREDADEPGR 0 0 0 0 0 0 0 0 0 0 10.0976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.194 11.0148 O60244 MED14_HUMAN Mediator of RNA polymerase II transcription subunit 14 (Activator-recruited cofactor 150 kDa component) (ARC150) (Cofactor required for Sp1 transcriptional activation subunit 2) (CRSP complex subunit 2) (Mediator complex subunit 14) (RGR1 homolog) (hRGR1) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) MED14 ARC150 CRSP2 CXorf4 DRIP150 EXLM1 RGR1 TRAP170 Homo sapiens (Human) positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA polymerase II preinitiation complex assembly [GO:0051123]; somatic stem cell population maintenance [GO:0035019] core mediator complex [GO:0070847]; mediator complex [GO:0016592]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] nuclear receptor coactivator activity [GO:0030374]; nuclear vitamin D receptor binding [GO:0042809]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712] 0.89939 -0.6565 AGTSSQTMPTNMPPPRK 0 0 0 0 0 0 0 0 9.59429 0 0 0 9.11437 0 9.20784 10.5258 10.629 10.5113 0 0 0 0 0 0 11.0079 10.103 0 O60264 SMCA5_HUMAN SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5) (EC 3.6.4.-) (Sucrose nonfermenting protein 2 homolog) (hSNF2H) SMARCA5 SNF2H WCRF135 Homo sapiens (Human) cellular response to leukemia inhibitory factor [GO:1990830]; chromatin remodeling [GO:0006338]; DNA repair [GO:0006281]; DNA-templated transcription initiation [GO:0006352]; heterochromatin formation [GO:0031507]; negative regulation of mitotic chromosome condensation [GO:1905213]; negative regulation of transcription by RNA polymerase I [GO:0016479]; nucleosome assembly [GO:0006334]; positive regulation of DNA replication [GO:0045740]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of histone methylation [GO:0031062]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; rDNA heterochromatin formation [GO:0000183]; regulation of DNA methylation [GO:0044030]; regulation of DNA replication [GO:0006275]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] ACF complex [GO:0016590]; B-WICH complex [GO:0110016]; CHRAC [GO:0008623]; chromatin silencing complex [GO:0005677]; condensed chromosome [GO:0000793]; fibrillar center [GO:0001650]; NoRC complex [GO:0090536]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NURF complex [GO:0016589]; pericentric heterochromatin [GO:0005721]; RSF complex [GO:0031213]; site of double-strand break [GO:0035861]; WICH complex [GO:0090535] "ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent activity, acting on DNA [GO:0008094]; ATP-dependent chromatin remodeler activity [GO:0140658]; DNA binding [GO:0003677]; helicase activity [GO:0004386]; histone octamer slider activity [GO:0140751]; nucleosome binding [GO:0031491]" 0.96885 -6.9593 ATNVCTRFEDSPSYVK 0 12.6841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.299 0 0 0 0 0 0 0 8.73176 0 O60266 ADCY3_HUMAN "Adenylate cyclase type 3 (EC 4.6.1.1) (ATP pyrophosphate-lyase 3) (Adenylate cyclase type III) (AC-III) (Adenylate cyclase, olfactive type) (Adenylyl cyclase 3) (AC3)" ADCY3 KIAA0511 Homo sapiens (Human) acrosome reaction [GO:0007340]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP biosynthetic process [GO:0006171]; cellular response to forskolin [GO:1904322]; flagellated sperm motility [GO:0030317]; intracellular signal transduction [GO:0035556]; olfactory learning [GO:0008355]; sensory perception of smell [GO:0007608]; signal transduction [GO:0007165]; single fertilization [GO:0007338] ciliary membrane [GO:0060170]; cilium [GO:0005929]; cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; plasma membrane [GO:0005886] adenylate cyclase activity [GO:0004016]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872] 0.95499 -1.6194 GLLPDRVTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.04232 0 10.7006 0 0 0 0 0 O60271 JIP4_HUMAN C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (Cancer/testis antigen 89) (CT89) (Human lung cancer oncogene 6 protein) (HLC-6) (JNK-associated leucine-zipper protein) (JLP) (Mitogen-activated protein kinase 8-interacting protein 4) (Proliferation-inducing protein 6) (Protein highly expressed in testis) (PHET) (Sperm surface protein) (Sperm-associated antigen 9) (Sperm-specific protein) (Sunday driver 1) SPAG9 HSS KIAA0516 MAPK8IP4 SYD1 HLC6 Homo sapiens (Human) "lysosome localization [GO:0032418]; negative regulation of dendrite extension [GO:1903860]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron differentiation [GO:0045666]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]" acrosomal vesicle [GO:0001669]; centriolar satellite [GO:0034451]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lysosomal membrane [GO:0005765]; perinuclear region of cytoplasm [GO:0048471] identical protein binding [GO:0042802]; JUN kinase binding [GO:0008432]; kinesin binding [GO:0019894]; MAP-kinase scaffold activity [GO:0005078]; signaling receptor complex adaptor activity [GO:0030159] 0.96714 -2.8638 AGPSAQEPGSQTPLK 0 0 9.15697 0 0 0 0 0 0 0 0 0 10.099 0 0 0 0 0 0 9.22064 9.41223 9.59546 0 0 9.63038 0 0 O60281 ZN292_HUMAN Zinc finger protein 292 ZNF292 KIAA0530 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]" 0.96928 -4.5654 EIKQLRER 0 0 0 0 0 0 10.1747 0 9.90091 0 14.5416 0 0 0 0 0 0 0 0 0 9.25484 9.33735 0 0 0 0 0 O60282 KIF5C_HUMAN Kinesin heavy chain isoform 5C (EC 3.6.4.-) (Kinesin heavy chain neuron-specific 2) (Kinesin-1) KIF5C KIAA0531 NKHC2 Homo sapiens (Human) anterograde axonal protein transport [GO:0099641]; anterograde dendritic transport of neurotransmitter receptor complex [GO:0098971]; axon guidance [GO:0007411]; motor neuron axon guidance [GO:0008045]; mRNA transport [GO:0051028]; organelle organization [GO:0006996]; synaptic vesicle transport [GO:0048489] axon cytoplasm [GO:1904115]; axonal growth cone [GO:0044295]; ciliary rootlet [GO:0035253]; dendrite cytoplasm [GO:0032839]; distal axon [GO:0150034]; kinesin complex [GO:0005871]; microtubule [GO:0005874]; neuronal cell body [GO:0043025] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777]; plus-end-directed microtubule motor activity [GO:0008574] 0.96716 -2.8444 ALESALKEAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.01814 0 0 0 0 O60284 ST18_HUMAN Suppression of tumorigenicity 18 protein (Zinc finger protein 387) ST18 KIAA0535 ZNF387 Homo sapiens (Human) interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6-mediated signaling pathway [GO:0070102]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; tumor necrosis factor-mediated signaling pathway [GO:0033209] chromatin [GO:0000785]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; zinc ion binding [GO:0008270]" 0.96886 -7.6849 ADCQEDRSDR 0 0 0 0 0 10.7131 0 0 0 0 0 0 0 0 0 11.658 9.09141 11.5544 0 10.5801 0 0 0 0 0 0 0 O60285 NUAK1_HUMAN NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5) (ARK5) (Omphalocele kinase 1) NUAK1 ARK5 KIAA0537 OMPHK1 Homo sapiens (Human) cell adhesion [GO:0007155]; cellular response to glucose starvation [GO:0042149]; DNA damage response [GO:0006974]; intracellular signal transduction [GO:0035556]; negative regulation of TOR signaling [GO:0032007]; protein phosphorylation [GO:0006468]; regulation of cell adhesion [GO:0030155]; regulation of cell population proliferation [GO:0042127]; regulation of cellular senescence [GO:2000772]; regulation of myosin-light-chain-phosphatase activity [GO:0035507]; regulation of signal transduction by p53 class mediator [GO:1901796] cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; microtubule cytoskeleton [GO:0015630]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.78359 0.25306 ESGYYSSPER 0 8.89163 8.60733 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0779 0 O60287 NPA1P_HUMAN Nucleolar pre-ribosomal-associated protein 1 (Nucleolar protein 254 kDa) (URB1 ribosome biogenesis 1 homolog) URB1 C21orf108 KIAA0539 NOP254 NPA1 Homo sapiens (Human) "maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]" fibrillar center [GO:0001650]; nucleolus [GO:0005730] RNA binding [GO:0003723] 0.96764 -2.7882 ATVIQAFRDMNR 11.8469 11.7471 0 0 0 0 0 0 0 0 0 11.7322 0 9.76847 0 9.8475 0 0 0 0 0 0 9.9076 0 0 10.1232 9.50277 O60290 ZN862_HUMAN Zinc finger protein 862 ZNF862 KIAA0543 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983] 0.91901 -0.89412 ELYRDVMR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1038 9.95447 0 0 9.43233 0 0 0 0 O60291 MGRN1_HUMAN E3 ubiquitin-protein ligase MGRN1 (EC 2.3.2.27) (Mahogunin RING finger protein 1) (RING finger protein 156) (RING-type E3 ubiquitin transferase MGRN1) MGRN1 KIAA0544 RNF156 Homo sapiens (Human) endosome to lysosome transport [GO:0008333]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of smoothened signaling pathway [GO:0045879]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567] cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.96904 -3.3761 IDFSEWK 0 0 0 0 0 0 0 0 0 0 0 8.88347 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60292 SI1L3_HUMAN Signal-induced proliferation-associated 1-like protein 3 (SIPA1-like protein 3) (SPA-1-like protein 3) SIPA1L3 KIAA0545 SPAL3 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; cytoskeleton organization [GO:0007010]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell polarity [GO:0090162]; eye development [GO:0001654]; hematopoietic progenitor cell differentiation [GO:0002244]; regulation of small GTPase mediated signal transduction [GO:0051056] apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; tricellular tight junction [GO:0061689] GTPase activator activity [GO:0005096] 0.96368 -2.6462 DSLLPLQPTK 0 0 9.90847 0 0 0 0 12.5262 8.9956 0 0 8.66587 0 9.40633 0 0 0 0 0 0 0 0 0 0 0 9.76233 0 O60293 ZC3H1_HUMAN Zinc finger C3H1 domain-containing protein (Coiled-coil domain-containing protein 131) (Proline/serine-rich coiled-coil protein 2) ZFC3H1 CCDC131 KIAA0546 PSRC2 Homo sapiens (Human) RNA processing [GO:0006396] exosome (RNase complex) [GO:0000178]; extracellular space [GO:0005615]; nucleus [GO:0005634] metal ion binding [GO:0046872] 0.96133 -2.6011 ITKLTEQLQATEK 12.8872 9.99223 0 0 0 0 0 0 0 0 9.11353 0 0 0 0 9.32114 0 0 0 0 9.7917 0 0 9.57115 0 0 0 O60299 LZTS3_HUMAN Leucine zipper putative tumor suppressor 3 (ProSAP-interacting protein 1) (ProSAPiP1) LZTS3 KIAA0552 PROSAPIP1 Homo sapiens (Human) regulation of dendritic spine morphogenesis [GO:0061001] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dendritic spine [GO:0043197]; postsynaptic density [GO:0014069]; synapse [GO:0045202] 0.96914 -3.2065 EQEVAALR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.41 O60303 KATIP_HUMAN Katanin-interacting protein KATNIP KIAA0556 Homo sapiens (Human) cerebrospinal fluid circulation [GO:0090660] cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; extracellular space [GO:0005615] 0.96898 -3.3152 AERSWSCSR 0 0 0 0 0 0 0 0 0 9.24165 0 0 0 0 8.97195 0 15.014 0 12.9135 0 0 0 0 0 0 0 0 O60304 ZN500_HUMAN Zinc finger protein 500 (Zinc finger protein with KRAB and SCAN domains 18) ZNF500 KIAA0557 ZKSCAN18 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96761 -2.3342 QLFRLFCYQEVAGPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4465 0 0 10.0639 0 0 0 0 0 0 O60306 AQR_HUMAN RNA helicase aquarius (EC 3.6.4.13) (Intron-binding protein of 160 kDa) (IBP160) AQR KIAA0560 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]" catalytic step 2 spliceosome [GO:0071013]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type catalytic step 2 spliceosome [GO:0071007] 3'-5' RNA helicase activity [GO:0034458]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727] 0.96959 -3.5275 AAPAQPK 16.8949 16.7169 16.7751 15.5053 16.329 15.3995 17.1774 17.1179 17.1312 17.3483 17.1318 17.0092 9.09527 14.7427 15.6115 15.1803 15.0285 15.254 12.1367 12.1328 12.314 12.9294 12.8211 12.926 11.5673 11.2909 12.6022 O60307 MAST3_HUMAN Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1) MAST3 KIAA0561 Homo sapiens (Human) cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; proteolysis [GO:0006508] cytoplasm [GO:0005737] ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.92118 -1.1156 LDGEAGR 0 0 0 0 0 0 0 10.5022 0 0 0 0 0 0 0 0 10.9654 0 0 0 0 0 0 0 0 0 0 O60308 CE104_HUMAN Centrosomal protein of 104 kDa (Cep104) CEP104 KIAA0562 Homo sapiens (Human) centriole [GO:0005814]; cilium [GO:0005929]; cytoplasm [GO:0005737]; spindle pole [GO:0000922] glutamate binding [GO:0016595]; glycine binding [GO:0016594]; thienylcyclohexylpiperidine binding [GO:0016596] 0.93982 -1.3262 EIQAEVQEK 8.86567 9.07058 0 0 0 0 0 0 0 0 0 10.1684 0 0 0 0 0 0 10.1933 0 0 0 0 0 0 0 0 O60309 L37A3_HUMAN Leucine-rich repeat-containing protein 37A3 LRRC37A3 KIAA0563 Homo sapiens (Human) membrane [GO:0016020] 0.91648 -0.8493 ALTAPEEHK 0 0 0 0 8.65528 10.002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60312 AT10A_HUMAN Phospholipid-transporting ATPase VA (EC 7.6.2.1) (ATPase class V type 10A) (Aminophospholipid translocase VA) (P4-ATPase flippase complex alpha subunit ATP10A) ATP10A ATP10C ATPVA ATPVC KIAA0566 Homo sapiens (Human) monoatomic ion transmembrane transport [GO:0034220]; phospholipid translocation [GO:0045332]; positive regulation of membrane tubulation [GO:1903527]; regulation of cell shape [GO:0008360] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; phospholipid-translocating ATPase complex [GO:1990531]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled intramembrane lipid transporter activity [GO:0140326]; glycosylceramide flippase activity [GO:0140351]; magnesium ion binding [GO:0000287]; phosphatidylcholine flippase activity [GO:0140345]; phosphatidylcholine floppase activity [GO:0090554] 0.96177 -2.0707 DSGTEHSSGRTVK 0 0 0 0 0 0 0 0 0 9.40305 0 0 0 0 0 0 0 9.85969 10.5515 0 0 0 0 0 0 0 0 O60313 OPA1_HUMAN "Dynamin-like 120 kDa protein, mitochondrial (EC 3.6.5.5) (Optic atrophy protein 1) [Cleaved into: Dynamin-like 120 kDa protein, form S1]" OPA1 KIAA0567 Homo sapiens (Human) apoptotic process [GO:0006915]; axonal transport of mitochondrion [GO:0019896]; cellular senescence [GO:0090398]; GTP metabolic process [GO:0046039]; inner mitochondrial membrane organization [GO:0007007]; membrane tubulation [GO:0097749]; mitochondrial fission [GO:0000266]; mitochondrial fusion [GO:0008053]; mitochondrial genome maintenance [GO:0000002]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; neural tube closure [GO:0001843]; protein complex oligomerization [GO:0051259]; visual perception [GO:0007601] axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; membrane [GO:0016020]; microtubule [GO:0005874]; mitochondrial crista [GO:0030061]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial membrane [GO:0031966]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] cardiolipin binding [GO:1901612]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; phosphatidic acid binding [GO:0070300] 0.96955 -3.1279 EAVKEESIKR 10.2924 0 0 7.83118 0 0 0 9.82372 0 0 0 0 0 10.9513 10.9377 0 0 0 9.97499 0 10.9114 0 0 0 0 0 0 O60315 ZEB2_HUMAN Zinc finger E-box-binding homeobox 2 (Smad-interacting protein 1) (SMADIP1) (Zinc finger homeobox protein 1b) ZEB2 KIAA0569 SIP1 ZFHX1B ZFX1B HRIHFB2411 Homo sapiens (Human) anatomical structure development [GO:0048856]; developmental pigmentation [GO:0048066]; melanocyte migration [GO:0097324]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanocyte differentiation [GO:0045636]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; regulation of melanosome organization [GO:1903056]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; phosphatase regulator activity [GO:0019208]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96723 -2.8673 EAEEREAAER 0 0 0 0 0 0 0 0 0 9.44207 9.62857 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60318 GANP_HUMAN Germinal-center associated nuclear protein (GANP) (EC 2.3.1.48) (80 kDa MCM3-associated protein) (MCM3 acetylating protein) (MCM3AP) (EC 2.3.1.-) (MCM3 acetyltransferase) MCM3AP GANP KIAA0572 MAP80 Homo sapiens (Human) mRNA export from nucleus [GO:0006406]; nucleosome organization [GO:0034728]; poly(A)+ mRNA export from nucleus [GO:0016973]; protein transport [GO:0015031]; somatic hypermutation of immunoglobulin genes [GO:0016446] chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nuclear pore nuclear basket [GO:0044615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription export complex 2 [GO:0070390] chromatin binding [GO:0003682]; histone acetyltransferase activity [GO:0004402]; histone binding [GO:0042393]; histone H3 acetyltransferase activity [GO:0010484]; nucleic acid binding [GO:0003676] 0.96929 -7.3423 DLLGASGLMLLLPPKMK 0 0 0 0 0 0 0 0 0 0 9.62854 0 0 0 0 0 0 0 0 0 11.4204 0 0 8.12939 0 0 0 O60320 EREP2_HUMAN Protein ENTREP2 (Endosomal transmembrane epsin interactor 2) (Transmembrane protein 228) ENTREP2 FAM189A1 KIAA0574 TMEM228 Homo sapiens (Human) membrane [GO:0016020] 0.67232 0.39371 PPAGGPR 0 8.76222 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60331 PI51C_HUMAN Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (PIP5K1gamma) (PtdIns(4)P-5-kinase 1 gamma) (EC 2.7.1.68) (Type I phosphatidylinositol 4-phosphate 5-kinase gamma) PIP5K1C KIAA0589 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; adherens junction assembly [GO:0034333]; cell-cell adhesion [GO:0098609]; clathrin-dependent endocytosis [GO:0072583]; membrane organization [GO:0061024]; neutrophil chemotaxis [GO:0030593]; phagocytosis [GO:0006909]; phosphatidylinositol biosynthetic process [GO:0006661]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079] adherens junction [GO:0005912]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; focal adhesion [GO:0005925]; nucleoplasm [GO:0005654]; phagocytic cup [GO:0001891]; presynapse [GO:0098793]; ruffle membrane [GO:0032587]; uropod [GO:0001931] "1-phosphatidylinositol-4-phosphate 5-kinase activity [GO:0016308]; ATP binding [GO:0005524]; phosphatidylinositol-3,4-bisphosphate 5-kinase activity [GO:0052812]" 0.84853 0.16405 FMSNTVFR 0 0 9.06738 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60333 KIF1B_HUMAN Kinesin-like protein KIF1B (Klp) KIF1B KIAA0591 KIAA1448 Homo sapiens (Human) anterograde axonal transport [GO:0008089]; apoptotic process [GO:0006915]; cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]; neuromuscular synaptic transmission [GO:0007274]; neuron-neuron synaptic transmission [GO:0007270]; vesicle-mediated transport [GO:0016192] axon [GO:0030424]; axon cytoplasm [GO:1904115]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; kinesin complex [GO:0005871]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; synaptic vesicle [GO:0008021] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; kinesin binding [GO:0019894]; microtubule binding [GO:0008017]; plus-end-directed microtubule motor activity [GO:0008574] 0.96384 -2.2202 SLRSLFGSGYSK 0 0 0 0 0 0 0 10.3744 0 0 0 0 0 0 0 0 0 0 0 0 10.658 0 0 0 0 0 8.87403 O60336 MABP1_HUMAN Mitogen-activated protein kinase-binding protein 1 (JNK-binding protein 1) (JNKBP-1) MAPKBP1 JNKBP1 KIAA0596 Homo sapiens (Human) negative regulation of defense response to bacterium [GO:1900425]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-8 production [GO:0032717]; positive regulation of JNK cascade [GO:0046330] cytoplasm [GO:0005737]; mitotic spindle pole [GO:0097431]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] 0.92297 -1.0799 FWYLDDSKTSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.81218 0 0 0 0 0 0 0 0 O60337 MARH6_HUMAN E3 ubiquitin-protein ligase MARCHF6 (EC 2.3.2.27) (Doa10 homolog) (Membrane-associated RING finger protein 6) (Membrane-associated RING-CH protein VI) (MARCH-VI) (Protein TEB-4) (RING finger protein 176) (RING-type E3 ubiquitin transferase MARCHF6) MARCHF6 KIAA0597 MARCH6 RNF176 TEB4 Homo sapiens (Human) endoplasmic reticulum mannose trimming [GO:1904380]; ERAD pathway [GO:0036503]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; ubiquitin-dependent ERAD pathway [GO:0030433] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum quality control compartment [GO:0044322]; ER ubiquitin ligase complex [GO:0000835]; membrane [GO:0016020] enzyme binding [GO:0019899]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; ubiquitin-specific protease binding [GO:1990381]; zinc ion binding [GO:0008270] 0.94545 -1.3413 LYEHIKNDK 0 0 0 0 0 0 0 0 0 12.7272 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60343 TBCD4_HUMAN TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160) TBC1D4 AS160 KIAA0603 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; cellular response to insulin stimulus [GO:0032869]; negative regulation of vesicle fusion [GO:0031339]; vesicle-mediated transport [GO:0016192] cytosol [GO:0005829]; vesicle [GO:0031982] GTPase activator activity [GO:0005096] 0.93274 -1.2593 DLNCNPNNKAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0232 9.0641 0 0 0 0 O60347 TBC12_HUMAN TBC1 domain family member 12 TBC1D12 KIAA0608 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; regulation of autophagosome assembly [GO:2000785] autophagosome [GO:0005776]; recycling endosome [GO:0055037] GTPase activator activity [GO:0005096] 0.81225 0.22257 AGGRESR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.014 0 0 0 11.1415 0 0 O60353 FZD6_HUMAN Frizzled-6 (Fz-6) (hFz6) FZD6 Homo sapiens (Human) "canonical Wnt signaling pathway [GO:0060070]; cell proliferation in midbrain [GO:0033278]; embryonic nail plate morphogenesis [GO:0035880]; establishment of body hair planar orientation [GO:0048105]; hair follicle development [GO:0001942]; inner ear morphogenesis [GO:0042472]; midbrain morphogenesis [GO:1904693]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; neural tube closure [GO:0001843]; non-canonical Wnt signaling pathway [GO:0035567]; platelet activation [GO:0030168]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" apical plasma membrane [GO:0016324]; apicolateral plasma membrane [GO:0016327]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; endoplasmic reticulum membrane [GO:0005789]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; ubiquitin protein ligase binding [GO:0031625]; Wnt receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147] 0.91478 -0.80409 DPISESRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0351 O60359 CCG3_HUMAN Voltage-dependent calcium channel gamma-3 subunit (Neuronal voltage-gated calcium channel gamma-3 subunit) (Transmembrane AMPAR regulatory protein gamma-3) (TARP gamma-3) CACNG3 Homo sapiens (Human) "calcium ion transport [GO:0006816]; neurotransmitter receptor internalization [GO:0099590]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; neurotransmitter receptor transport, postsynaptic endosome to lysosome [GO:0098943]; positive regulation of AMPA receptor activity [GO:2000969]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein localization [GO:0008104]; protein targeting [GO:0006605]; regulation of AMPA receptor activity [GO:2000311]; transmission of nerve impulse [GO:0019226]" AMPA glutamate receptor complex [GO:0032281]; dendrite [GO:0030425]; endocytic vesicle membrane [GO:0030666]; excitatory synapse [GO:0060076]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; Schaffer collateral - CA1 synapse [GO:0098685]; somatodendritic compartment [GO:0036477]; voltage-gated calcium channel complex [GO:0005891] channel regulator activity [GO:0016247]; ionotropic glutamate receptor binding [GO:0035255]; PDZ domain binding [GO:0030165]; voltage-gated calcium channel activity [GO:0005245] 0.94807 -1.3627 STFARLPPYR 0 0 0 9.08651 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60381 HBP1_HUMAN HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1) HBP1 Homo sapiens (Human) regulation of cell cycle [GO:0051726]; regulation of transcription by RNA polymerase II [GO:0006357]; Wnt signaling pathway [GO:0016055] chromatin [GO:0000785]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA binding [GO:0003723]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.77209 0.26986 SLHSYARPPPVSSSSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9025 0 0 0 0 0 0 0 9.08194 0 0 0 O60383 GDF9_HUMAN Growth/differentiation factor 9 (GDF-9) GDF9 Homo sapiens (Human) BMP signaling pathway [GO:0030509]; female gamete generation [GO:0007292]; negative regulation of cell growth [GO:0030308]; oocyte growth [GO:0001555]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; regulation of progesterone secretion [GO:2000870]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179] cytoplasm [GO:0005737]; extracellular space [GO:0005615] cytokine activity [GO:0005125]; growth factor activity [GO:0008083] 0.96114 -2.5958 EGIPKSNRSHLYNTVR 0 0 0 0 0 0 0 0 12.6468 12.7272 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60393 NOBOX_HUMAN Homeobox protein NOBOX NOBOX Homo sapiens (Human) oogenesis [GO:0048477]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]" 0.88029 0.014419 SDQLEELEK 0 0 0 0 0 0 0 0 0 11.0801 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60423 AT8B3_HUMAN Phospholipid-transporting ATPase IK (EC 7.6.2.1) (ATPase class I type 8B member 3) ATP8B3 ATP1K FOS37502_2 Homo sapiens (Human) binding of sperm to zona pellucida [GO:0007339]; establishment of localization in cell [GO:0051649]; Golgi organization [GO:0007030]; phospholipid translocation [GO:0045332] acrosomal membrane [GO:0002080]; endoplasmic reticulum membrane [GO:0005789]; phospholipid-translocating ATPase complex [GO:1990531]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled intramembrane lipid transporter activity [GO:0140326]; magnesium ion binding [GO:0000287]; phosphatidylserine floppase activity [GO:0090556] 0.91617 -0.76553 EPRALAQNVNMDEAWQELGQSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.88724 0 0 10.2235 0 0 0 O60427 FADS1_HUMAN Acyl-CoA (8-3)-desaturase (EC 1.14.19.44) (Delta(5) fatty acid desaturase) (D5D) (Delta(5) desaturase) (Delta-5 desaturase) (Fatty acid desaturase 1) FADS1 FADSD5 Homo sapiens (Human) alpha-linolenic acid metabolic process [GO:0036109]; cell-cell signaling [GO:0007267]; cellular response to starvation [GO:0009267]; icosanoid biosynthetic process [GO:0046456]; linoleic acid metabolic process [GO:0043651]; lipid metabolic process [GO:0006629]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid biosynthetic process [GO:0008654]; regulation of cell differentiation [GO:0045595]; regulation of DNA-templated transcription [GO:0006355]; unsaturated fatty acid biosynthetic process [GO:0006636] endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739] "acyl-CoA delta5-desaturase activity [GO:0062076]; C-5 sterol desaturase activity [GO:0000248]; linoleoyl-CoA desaturase activity [GO:0016213]; omega-6 fatty acid desaturase activity [GO:0045485]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]" 0.96249 -2.0316 ELTDEFRELR 0 0 8.71853 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60431 OR1I1_HUMAN Olfactory receptor 1I1 (Olfactory receptor 19-20) (OR19-20) OR1I1 Homo sapiens (Human) signal transduction [GO:0007165] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.87069 0.047855 MLANIQAQSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6964 0 0 0 0 0 0 0 0 0 0 0 O60437 PEPL_HUMAN Periplakin (190 kDa paraneoplastic pemphigus antigen) (195 kDa cornified envelope precursor protein) PPL KIAA0568 Homo sapiens (Human) intermediate filament cytoskeleton organization [GO:0045104]; keratinization [GO:0031424]; response to mechanical stimulus [GO:0009612]; wound healing [GO:0042060] cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; desmosome [GO:0030057]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886] cadherin binding [GO:0045296]; structural constituent of cytoskeleton [GO:0005200]; structural molecule activity [GO:0005198] 0.9695 -4.4232 AESEVANLR 0 9.22533 0 0 0 0 0 9.5799 10.1397 0 0 9.9629 9.11803 0 0 0 0 0 0 0 0 0 0 0 9.7817 0 0 O60447 EVI5_HUMAN Ecotropic viral integration site 5 protein homolog (EVI-5) (Neuroblastoma stage 4S gene protein) EVI5 NB4S Homo sapiens (Human) "activation of GTPase activity [GO:0090630]; cell cycle [GO:0007049]; cell division [GO:0051301]; positive regulation of GTPase activity [GO:0043547]; retrograde transport, endosome to Golgi [GO:0042147]" cytosol [GO:0005829]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; spindle [GO:0005819] GTPase activator activity [GO:0005096]; small GTPase binding [GO:0031267] 0.96933 -5.646 DLEEHWQRHLAR 0 0 0 0 0 0 0 0 0 0 0 0 9.41111 11.0912 0 0 0 0 0 0 0 0 0 0 16.0621 12.0039 0 O60449 LY75_HUMAN Lymphocyte antigen 75 (Ly-75) (C-type lectin domain family 13 member B) (DEC-205) (gp200-MR6) (CD antigen CD205) LY75 CD205 CLEC13B Homo sapiens (Human) endocytosis [GO:0006897]; immune response [GO:0006955]; inflammatory response [GO:0006954] external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] carbohydrate binding [GO:0030246]; signaling receptor activity [GO:0038023] 0.054167 1.4024 CLGLDITK 0 0 0 11.9136 9.02644 8.69995 0 18.035 0 10.4172 11.5021 11.2242 9.77022 0 0 0 0 0 12.3278 0 0 0 0 0 0 0 0 O60462 NRP2_HUMAN Neuropilin-2 (Vascular endothelial cell growth factor 165 receptor 2) NRP2 VEGF165R2 Homo sapiens (Human) angiogenesis [GO:0001525]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cellular response to leukemia inhibitory factor [GO:1990830]; dorsal root ganglion morphogenesis [GO:1904835]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; negative chemotaxis [GO:0050919]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; regulation of postsynapse organization [GO:0099175]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; trigeminal ganglion development [GO:0061551]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649] axon [GO:0030424]; extracellular region [GO:0005576]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; semaphorin receptor complex [GO:0002116] cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; semaphorin receptor activity [GO:0017154]; signaling receptor activity [GO:0038023]; vascular endothelial growth factor receptor activity [GO:0005021] 0.9086 -0.74352 GVIIQGAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.239 0 O60469 DSCAM_HUMAN Cell adhesion molecule DSCAM (CHD2) (Down syndrome cell adhesion molecule) DSCAM Homo sapiens (Human) axon guidance [GO:0007411]; camera-type eye photoreceptor cell differentiation [GO:0060219]; cell adhesion [GO:0007155]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; locomotory behavior [GO:0007626]; negative regulation of cell adhesion [GO:0007162]; nervous system development [GO:0007399]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of phosphorylation [GO:0042327]; post-embryonic retina morphogenesis in camera-type eye [GO:0060060]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] axon [GO:0030424]; dendrite [GO:0030425]; extracellular region [GO:0005576]; growth cone [GO:0030426]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; synapse [GO:0045202] cell-cell adhesion mediator activity [GO:0098632]; netrin receptor binding [GO:1990890]; protein tyrosine kinase binding [GO:1990782] 0.96576 -2.361 DVQNEDGLYNYR 0 0 0 10.2635 0 0 0 0 0 0 9.52227 0 0 0 0 0 0 0 0 10.5823 0 0 0 0 0 0 0 O60476 MA1A2_HUMAN "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB (EC 3.2.1.113) (Mannosidase alpha class 1A member 2) (Processing alpha-1,2-mannosidase IB) (Alpha-1,2-mannosidase IB)" MAN1A2 MAN1B Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; Golgi apparatus mannose trimming [GO:1904381]; lung alveolus development [GO:0048286]; N-glycan processing [GO:0006491]; protein glycosylation [GO:0006486]; respiratory gaseous exchange by respiratory system [GO:0007585] endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020] "calcium ion binding [GO:0005509]; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [GO:0004571]" 0.82165 0.21754 ADHEKALEEAK 0 0 0 0 0 0 0 0 0 0 0 0 10.8151 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60477 BRNP1_HUMAN BMP/retinoic acid-inducible neural-specific protein 1 (Deleted in bladder cancer protein 1) BRINP1 DBC1 DBCCR1 FAM5A IB3089A Homo sapiens (Human) behavioral fear response [GO:0001662]; cell cycle [GO:0007049]; cellular response to retinoic acid [GO:0071300]; central nervous system neuron development [GO:0021954]; exploration behavior [GO:0035640]; maternal behavior [GO:0042711]; negative regulation of cell cycle [GO:0045786]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of neurogenesis [GO:0050768]; positive regulation of neuron differentiation [GO:0045666]; short-term memory [GO:0007614]; social behavior [GO:0035176]; vocalization behavior [GO:0071625] cytoplasm [GO:0005737] 0.95857 -1.6942 LDTFFDPRWRK 0 0 0 0 0 0 0 0 8.85823 0 0 0 0 0 0 0 0 0 11.7084 0 0 0 0 0 0 0 0 O60478 G137B_HUMAN Integral membrane protein GPR137B (Transmembrane 7 superfamily member 1 protein) GPR137B TM7SF1 Homo sapiens (Human) autophagy [GO:0006914]; negative regulation of bone resorption [GO:0045779]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of protein localization to lysosome [GO:0150032]; positive regulation of TORC1 signaling [GO:1904263]; regulation of autophagy [GO:0010506]; regulation of GTPase activity [GO:0043087]; regulation of macrophage activation [GO:0043030] lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886] 0.92248 -1.1221 SKYSPELLK 9.30437 0 8.94281 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60486 PLXC1_HUMAN Plexin-C1 (Virus-encoded semaphorin protein receptor) (CD antigen CD232) PLXNC1 VESPR Homo sapiens (Human) cell adhesion [GO:0007155]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of synapse pruning [GO:1905806]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287] cerebellar climbing fiber to Purkinje cell synapse [GO:0150053]; membrane [GO:0016020]; plasma membrane [GO:0005886]; semaphorin receptor complex [GO:0002116] semaphorin receptor activity [GO:0017154]; signaling receptor binding [GO:0005102] 0.88301 -0.08786 DLMEQCSNMQPKLMLR 0 0 0 0 0 8.94749 0 0 0 0 0 0 0 0 10.9001 12.1189 12.201 12.0221 10.4075 10.5581 11.4374 11.2174 0 11.187 11.9073 11.7998 11.8559 O60487 MPZL2_HUMAN Myelin protein zero-like protein 2 (Epithelial V-like antigen 1) MPZL2 EVA EVA1 UNQ606/PRO1192 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; cell-cell adhesion [GO:0098609]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] cytoskeleton [GO:0005856]; membrane [GO:0016020] 0.95453 -1.5017 DRVSWDGNPER 0 0 0 0 0 0 0 0 0 0 8.83261 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60488 ACSL4_HUMAN Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 4) (LACS 4) ACSL4 ACS4 FACL4 LACS4 Homo sapiens (Human) embryonic process involved in female pregnancy [GO:0060136]; fatty acid metabolic process [GO:0006631]; lipid biosynthetic process [GO:0008610]; lipid metabolic process [GO:0006629]; long-chain fatty acid metabolic process [GO:0001676]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]; negative regulation of prostaglandin secretion [GO:0032307]; neuron differentiation [GO:0030182]; positive regulation of cell growth [GO:0030307]; positive regulation of insulin secretion [GO:0032024] cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; membrane [GO:0016020]; mitochondria-associated endoplasmic reticulum membrane [GO:0044233]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; plasma membrane [GO:0005886] arachidonate-CoA ligase activity [GO:0047676]; ATP binding [GO:0005524]; long-chain fatty acid-CoA ligase activity [GO:0004467]; palmitoyl-CoA ligase activity [GO:0090433]; very long-chain fatty acid-CoA ligase activity [GO:0031957] 0.96931 -3.3096 DIERMYGGK 0 0 0 0 0 0 0 0 0 0 0 0 0 8.99359 0 0 0 0 0 8.79435 9.53726 0 0 0 0 0 0 O60493 SNX3_HUMAN Sorting nexin-3 (Protein SDP3) SNX3 Homo sapiens (Human) endocytic recycling [GO:0032456]; intralumenal vesicle formation [GO:0070676]; late endosome to Golgi transport [GO:0034499]; membrane invagination [GO:0010324]; negative regulation of early endosome to late endosome transport [GO:2000642]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein transport [GO:0051224]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of neuron projection development [GO:0010976]; protein to membrane docking [GO:0022615]; protein transport [GO:0015031]; regulation of Wnt signaling pathway [GO:0030111]; response to bacterium [GO:0009617] clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; early phagosome [GO:0032009]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; retromer complex [GO:0030904] "phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein phosphatase binding [GO:0019903]; retromer complex binding [GO:1905394]" 0.9336 -1.2817 FTTYEIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4589 0 0 O60496 DOK2_HUMAN Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) DOK2 Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; positive regulation of MAPK cascade [GO:0043410]; Ras protein signal transduction [GO:0007265]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] cytoplasm [GO:0005737]; cytosol [GO:0005829] transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068] 0.88349 -0.058471 DPAGLQHVQPAGQDFSASGWQPGTEYDNVVLKK 10.8943 0 10.9652 0 0 11.5501 0 0 10.9984 0 0 0 0 0 0 0 11.7074 0 0 0 0 0 0 0 0 0 0 O60499 STX10_HUMAN Syntaxin-10 (Syn10) STX10 SYN10 Homo sapiens (Human) "Golgi vesicle transport [GO:0048193]; intracellular protein transport [GO:0006886]; regulation of protein localization [GO:0032880]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906]" cytosol [GO:0005829]; endomembrane system [GO:0012505]; Golgi membrane [GO:0000139]; perinuclear region of cytoplasm [GO:0048471]; SNARE complex [GO:0031201]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588]; vesicle [GO:0031982] SNAP receptor activity [GO:0005484]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905] 0.92411 -0.99569 EELDWTTNELR 0 0 0 0 0 0 9.3612 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60502 OGA_HUMAN Protein O-GlcNAcase (OGA) (EC 3.2.1.169) (Beta-N-acetylglucosaminidase) (Beta-N-acetylhexosaminidase) (Beta-hexosaminidase) (Meningioma-expressed antigen 5) (N-acetyl-beta-D-glucosaminidase) (N-acetyl-beta-glucosaminidase) (Nuclear cytoplasmic O-GlcNAcase and acetyltransferase) (NCOAT) OGA HEXC KIAA0679 MEA5 MGEA5 Homo sapiens (Human) glycoprotein catabolic process [GO:0006516]; glycoprotein metabolic process [GO:0009100]; N-acetylglucosamine metabolic process [GO:0006044]; protein deglycosylation [GO:0006517]; protein O-linked glycosylation [GO:0006493] cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634] [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; hyalurononglucosaminidase activity [GO:0004415]; identical protein binding [GO:0042802] 0.92355 -1.1618 FLCGVVEGFYGRPWVMEQRK 0 8.80087 0 0 0 0 11.8975 0 0 0 0 11.1275 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60503 ADCY9_HUMAN Adenylate cyclase type 9 (EC 4.6.1.1) (ATP pyrophosphate-lyase 9) (Adenylate cyclase type IX) (ACIX) (Adenylyl cyclase 9) (AC9) ADCY9 KIAA0520 Homo sapiens (Human) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP biosynthetic process [GO:0006171]; in utero embryonic development [GO:0001701]; intracellular signal transduction [GO:0035556]; signal transduction [GO:0007165] axon [GO:0030424]; cytosol [GO:0005829]; dendrite [GO:0030425]; membrane [GO:0016020]; plasma membrane [GO:0005886] adenylate cyclase activity [GO:0004016]; ATP binding [GO:0005524]; metal ion binding [GO:0046872] 0.9556 -1.5452 CFPQTQR 0 0 0 0 0 0 0 0 0 0 12.6756 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60504 VINEX_HUMAN Vinexin (SH3-containing adapter molecule 1) (SCAM-1) (Sorbin and SH3 domain-containing protein 3) SORBS3 SCAM1 Homo sapiens (Human) cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; MAPK cascade [GO:0000165]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cytoskeleton organization [GO:0051495]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of stress fiber assembly [GO:0051496] cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634] structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166] 0.80061 0.2398 ELAELSAELDK 0 0 0 0 0 0 0 0 0 0 0 9.98057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60506 HNRPQ_HUMAN "Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) (Glycine- and tyrosine-rich RNA-binding protein) (GRY-RBP) (NS1-associated protein 1) (Synaptotagmin-binding, cytoplasmic RNA-interacting protein)" SYNCRIP HNRPQ NSAP1 Homo sapiens (Human) "cellular response to type II interferon [GO:0071346]; CRD-mediated mRNA stabilization [GO:0070934]; mRNA modification [GO:0016556]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; negative regulation of translation [GO:0017148]; osteoblast differentiation [GO:0001649]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of DNA demethylation [GO:1901537]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]" catalytic step 2 spliceosome [GO:0071013]; CRD-mediated mRNA stability complex [GO:0070937]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; GAIT complex [GO:0097452]; histone pre-mRNA 3'end processing complex [GO:0071204]; mCRD-mediated mRNA stability complex [GO:0106002]; membrane [GO:0016020]; mRNA editing complex [GO:0045293]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] mRNA 5'-UTR binding [GO:0048027]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723] 0 3.2742 AGPIWDLR 0 8.81577 10.1079 0 0 8.84216 9.36872 11.1769 10.0786 9.69759 9.80253 10.8961 9.51315 11.2037 9.34682 9.31427 10.1192 10.409 11.4049 9.82823 0 11.1286 10.5229 10.8729 11.2651 9.98598 9.97528 O60508 PRP17_HUMAN Pre-mRNA-processing factor 17 (Cell division cycle 40 homolog) (EH-binding protein 3) (Ehb3) (PRP17 homolog) (hPRP17) CDC40 EHB3 PRP17 PRPF17 Homo sapiens (Human) "embryonic brain development [GO:1990403]; mRNA splicing, via spliceosome [GO:0000398]" catalytic step 2 spliceosome [GO:0071013]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; U2-type catalytic step 2 spliceosome [GO:0071007] mRNA binding [GO:0003729]; RNA binding [GO:0003723] 0.42978 0.65943 KVPYCVKFNPDEDK 0 0 0 0 0 8.43158 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.82891 0 0 0 0 0 O60512 B4GT3_HUMAN "Beta-1,4-galactosyltransferase 3 (Beta-1,4-GalTase 3) (Beta4Gal-T3) (b4Gal-T3) (EC 2.4.1.-) (Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase) (Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase) (EC 2.4.1.38) (N-acetyllactosamine synthase) (EC 2.4.1.90) (Nal synthase) (Neolactotriaosylceramide beta-1,4-galactosyltransferase) (EC 2.4.1.275) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 3) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 3)" B4GALT3 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; galactosylceramide biosynthetic process [GO:0006682]; protein glycosylation [GO:0006486] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139] "beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; galactosyltransferase activity [GO:0008378]; metal ion binding [GO:0046872]; N-acetyllactosamine synthase activity [GO:0003945]" 0.91486 -0.78018 YPPGSSQAFRQEMLQR 0 0 0 0 0 15.4799 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60513 B4GT4_HUMAN "Beta-1,4-galactosyltransferase 4 (Beta-1,4-GalTase 4) (Beta4Gal-T4) (b4Gal-T4) (EC 2.4.1.-) (Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase) (Lactotriaosylceramide beta-1,4-galactosyltransferase) (EC 2.4.1.275) (N-acetyllactosamine synthase) (EC 2.4.1.90) (Nal synthase) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 4) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 4)" B4GALT4 UNQ552/PRO1109 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; keratan sulfate biosynthetic process [GO:0018146]; lactosylceramide biosynthetic process [GO:0001572]; membrane lipid metabolic process [GO:0006643]; protein glycosylation [GO:0006486] extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020] galactosyltransferase activity [GO:0008378]; metal ion binding [GO:0046872]; N-acetyllactosamine synthase activity [GO:0003945]; UDP-galactosyltransferase activity [GO:0035250] 0.95216 -1.3894 TDGLSSCSYK 0 0 0 8.95076 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60516 4EBP3_HUMAN Eukaryotic translation initiation factor 4E-binding protein 3 (4E-BP3) (eIF4E-binding protein 3) EIF4EBP3 Homo sapiens (Human) negative regulation of translational initiation [GO:0045947] cytoplasm [GO:0005737]; eukaryotic translation initiation factor 4F complex [GO:0016281]; membrane [GO:0016020] eukaryotic initiation factor 4E binding [GO:0008190]; translation repressor activity [GO:0030371] 0.84233 0.14814 DQLPDCYSTTPGGTLYATTPGGTR 0 0 0 0 0 0 0 0 0 0 0 0 0 11.6388 0 0 0 0 0 0 0 0 0 0 0 0 0 O60519 CRBL2_HUMAN cAMP-responsive element-binding protein-like 2 CREBL2 Homo sapiens (Human) cell cycle [GO:0007049]; cell differentiation [GO:0030154]; DNA-templated transcription [GO:0006351]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of glucose import [GO:0046326]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; protein stabilization [GO:0050821]; regulation of DNA-templated transcription [GO:0006355]; signal transduction [GO:0007165] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]" 0.95472 -1.5722 QSARECR 0 0 0 0 0 0 0 0 0 0 9.47151 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60522 TDRD6_HUMAN Tudor domain-containing protein 6 (Antigen NY-CO-45) (Cancer/testis antigen 41.2) (CT41.2) TDRD6 Homo sapiens (Human) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] chromatoid body [GO:0033391]; cytoplasm [GO:0005737] 0.96933 -6.165 AIVTKLDDK 11.1015 16.6947 0 0 0 15.3589 0 10.2244 17.0604 0 0 0 0 14.6651 0 15.1659 0 9.31295 12.1367 0 11.3069 0 12.8211 12.926 0 0 0 O60524 NEMF_HUMAN Ribosome quality control complex subunit NEMF (Antigen NY-CO-1) (Nuclear export mediator factor) (Serologically defined colon cancer antigen 1) NEMF SDCCAG1 Homo sapiens (Human) CAT tailing [GO:0140708]; nuclear export [GO:0051168]; protein-containing complex assembly [GO:0065003]; rescue of stalled ribosome [GO:0072344]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] cytosol [GO:0005829]; nucleus [GO:0005634]; RQC complex [GO:1990112] alpha-aminoacyl-tRNA binding [GO:1904678]; ribosomal large subunit binding [GO:0043023]; tRNA binding [GO:0000049] 0.96815 -2.7813 ATLLLESGIR 0 0 16.4762 9.4165 0 0 0 0 0 12.2478 0 0 9.69443 0 8.95974 8.92273 11.0593 0 0 9.16679 0 0 0 0 0 0 0 O60543 CIDEA_HUMAN Lipid transferase CIDEA (Cell death activator CIDE-A) (Cell death-inducing DFFA-like effector A) CIDEA Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to cold [GO:0070417]; lipid droplet fusion [GO:0160077]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of cytokine production [GO:0001818]; negative regulation of execution phase of apoptosis [GO:1900118]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of sequestering of triglyceride [GO:0010890]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to stilbenoid [GO:0035634]; temperature homeostasis [GO:0001659] cytoplasm [GO:0005737]; cytosol [GO:0005829]; lipid droplet [GO:0005811]; mitochondrial envelope [GO:0005740]; mitochondrion [GO:0005739]; nucleus [GO:0005634] lipid transfer activity [GO:0120013]; phosphatidic acid binding [GO:0070300]; protein homodimerization activity [GO:0042803] 0.8589 0.099661 DFIGCLNVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2854 0 0 O60547 GMDS_HUMAN "GDP-mannose 4,6 dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase) (GMD)" GMDS Homo sapiens (Human) 'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; Notch signaling pathway [GO:0007219] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062] "GDP-mannose 4,6-dehydratase activity [GO:0008446]; identical protein binding [GO:0042802]; NADP+ binding [GO:0070401]" 0.92596 -1.2126 NENEVGRCK 0 0 0 0 0 0 0 0 0 0 0 9.20504 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60548 FOXD2_HUMAN Forkhead box protein D2 (Forkhead-related protein FKHL17) (Forkhead-related transcription factor 9) (FREAC-9) FOXD2 FKHL17 FREAC9 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96433 -2.2702 EPGNPGK 0 0 8.32076 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60566 BUB1B_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (hBUBR1) (Mitotic checkpoint kinase MAD3L) (Protein SSK1) BUB1B BUBR1 MAD3L SSK1 Homo sapiens (Human) "apoptotic process [GO:0006915]; cell division [GO:0051301]; meiotic sister chromatid cohesion, centromeric [GO:0051754]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; mitotic spindle assembly checkpoint signaling [GO:0007094]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; phosphorylation [GO:0016310]; protein localization to chromosome, centromeric region [GO:0071459]" anaphase-promoting complex [GO:0005680]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; microtubule organizing center [GO:0005815]; mitotic checkpoint complex [GO:0033597]; outer kinetochore [GO:0000940]; perinuclear region of cytoplasm [GO:0048471]; spindle [GO:0005819] ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96761 -2.9958 AFEYEIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.97528 0 10.9385 0 0 0 0 0 0 0 0 9.9678 0 O60568 PLOD3_HUMAN "Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 (EC 1.14.11.4) (Lysyl hydroxylase 3) (LH3); Procollagen glycosyltransferase (EC 2.4.1.50) (EC 2.4.1.66) (Galactosylhydroxylysine-glucosyltransferase) (Procollagen galactosyltransferase) (Procollagen glucosyltransferase)]" PLOD3 Homo sapiens (Human) basement membrane assembly [GO:0070831]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; endothelial cell morphogenesis [GO:0001886]; epidermis morphogenesis [GO:0048730]; hydroxylysine biosynthetic process [GO:0046947]; in utero embryonic development [GO:0001701]; lung morphogenesis [GO:0060425]; neural tube development [GO:0021915]; peptidyl-lysine hydroxylation [GO:0017185]; protein localization [GO:0008104]; protein O-linked glycosylation [GO:0006493]; vasodilation [GO:0042311] collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; rough endoplasmic reticulum [GO:0005791]; trans-Golgi network [GO:0005802] iron ion binding [GO:0005506]; L-ascorbic acid binding [GO:0031418]; metal ion binding [GO:0046872]; procollagen galactosyltransferase activity [GO:0050211]; procollagen glucosyltransferase activity [GO:0033823]; procollagen-lysine 5-dioxygenase activity [GO:0008475]; small molecule binding [GO:0036094] 0.87052 0.04163 AVMNFVVR 0 0 15.2874 0 12.6306 0 14.625 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60603 TLR2_HUMAN Toll-like receptor 2 (Toll/interleukin-1 receptor-like protein 4) (CD antigen CD282) TLR2 TIL4 Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to bacterial lipopeptide [GO:0071221]; cellular response to diacyl bacterial lipopeptide [GO:0071726]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to triacyl bacterial lipopeptide [GO:0071727]; cellular response to type II interferon [GO:0071346]; central nervous system myelin formation [GO:0032289]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of diacyl bacterial lipopeptide [GO:0042496]; detection of triacyl bacterial lipopeptide [GO:0042495]; I-kappaB phosphorylation [GO:0007252]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; learning [GO:0007612]; leukotriene metabolic process [GO:0006691]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of phagocytosis [GO:0050765]; negative regulation of synapse assembly [GO:0051964]; nitric oxide metabolic process [GO:0046209]; positive regulation of cellular response to macrophage colony-stimulating factor stimulus [GO:1903974]; positive regulation of chemokine production [GO:0032722]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-18 production [GO:0032741]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of matrix metallopeptidase secretion [GO:1904466]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of toll-like receptor signaling pathway [GO:0034123]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of Wnt signaling pathway [GO:0030177]; response to fatty acid [GO:0070542]; response to hypoxia [GO:0001666]; response to insulin [GO:0032868]; response to progesterone [GO:0032570]; response to toxic substance [GO:0009636]; signal transduction [GO:0007165]; toll-like receptor signaling pathway [GO:0002224]; toll-like receptor TLR6:TLR2 signaling pathway [GO:0038124] cell body [GO:0044297]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; membrane raft [GO:0045121]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; secretory granule membrane [GO:0030667]; Toll-like receptor 1-Toll-like receptor 2 protein complex [GO:0035354]; Toll-like receptor 2-Toll-like receptor 6 protein complex [GO:0035355] "amyloid-beta binding [GO:0001540]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; lipopolysaccharide immune receptor activity [GO:0001875]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; pattern recognition receptor activity [GO:0038187]; peptidoglycan binding [GO:0042834]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; Toll-like receptor binding [GO:0035325]; transmembrane signaling receptor activity [GO:0004888]; triacyl lipopeptide binding [GO:0042497]" 0.96926 -3.4714 ASDNDRVIDPGK 0 0 0 11.6055 0 0 0 0 0 0 0 0 0 0 0 10.1881 0 0 0 0 0 0 0 0 0 0 0 O60610 DIAP1_HUMAN Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) DIAPH1 DIAP1 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament polymerization [GO:0030041]; cellular response to histamine [GO:0071420]; cytoskeleton organization [GO:0007010]; positive regulation of cell migration [GO:0030335]; protein localization to microtubule [GO:0035372]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule-based process [GO:0032886]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; sensory perception of sound [GO:0007605] actin filament [GO:0005884]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ficolin-1-rich granule membrane [GO:0101003]; microtubule organizing center [GO:0005815]; mitotic spindle [GO:0072686]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667] actin binding [GO:0003779]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; small GTPase binding [GO:0031267]; transmembrane transporter binding [GO:0044325] 0.93253 -1.2775 AGMSQKESSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.72253 8.88631 0 0 0 0 9.41808 0 0 0 O60645 EXOC3_HUMAN Exocyst complex component 3 (Exocyst complex component Sec6) EXOC3 SEC6 SEC6L1 Homo sapiens (Human) exocyst localization [GO:0051601]; exocytosis [GO:0006887]; membrane fission [GO:0090148]; mitotic cytokinesis [GO:0000281]; protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904]; vesicle tethering involved in exocytosis [GO:0090522] cytosol [GO:0005829]; exocyst [GO:0000145]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; midbody [GO:0030496]; perinuclear region of cytoplasm [GO:0048471]; presynaptic membrane [GO:0042734]; secretory granule membrane [GO:0030667] cadherin binding [GO:0045296]; SNARE binding [GO:0000149] 0.69702 0.3799 NLLNMYHQALSTR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3855 0 0 9.69368 0 0 0 0 0 0 0 0 0 0 O60658 PDE8A_HUMAN "High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (EC 3.1.4.53)" PDE8A Homo sapiens (Human) cAMP catabolic process [GO:0006198]; cellular response to epidermal growth factor stimulus [GO:0071364]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; regulation of DNA-templated transcription [GO:0006355]; signal transduction [GO:0007165] cytosol [GO:0005829]; extracellular exosome [GO:0070062] "3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; kinase binding [GO:0019900]; metal ion binding [GO:0046872]; protein kinase activator activity [GO:0030295]" 0.96958 -4.7548 AGFKCTVTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.2075 9.44232 10.1716 0 0 0 0 O60662 KLH41_HUMAN Kelch-like protein 41 (Kel-like protein 23) (Kelch repeat and BTB domain-containing protein 10) (Kelch-related protein 1) (Sarcosin) KLHL41 KBTBD10 KRP1 Homo sapiens (Human) myofibril assembly [GO:0030239]; protein ubiquitination [GO:0016567]; pseudopodium assembly [GO:0031269]; regulation of myoblast differentiation [GO:0045661]; regulation of myoblast proliferation [GO:2000291]; regulation of skeletal muscle cell differentiation [GO:2001014]; skeletal muscle cell differentiation [GO:0035914]; striated muscle contraction [GO:0006941] Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; M band [GO:0031430]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]; ruffle [GO:0001726]; sarcoplasmic reticulum membrane [GO:0033017] 0.96995 -5.2553 FIDCTLKAGDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.30813 0 0 0 0 0 O60663 LMX1B_HUMAN LIM homeobox transcription factor 1-beta (LIM/homeobox protein 1.2) (LMX-1.2) (LIM/homeobox protein LMX1B) LMX1B Homo sapiens (Human) dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral pattern formation [GO:0009953]; neuron differentiation [GO:0030182]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.93208 -1.2607 EGQLLCKGDYEK 0 0 0 0 0 0 0 8.97814 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60664 PLIN3_HUMAN Perilipin-3 (47 kDa mannose 6-phosphate receptor-binding protein) (47 kDa MPR-binding protein) (Cargo selection protein TIP47) (Mannose-6-phosphate receptor-binding protein 1) (Placental protein 17) (PP17) PLIN3 M6PRBP1 TIP47 Homo sapiens (Human) cellular response to glucose starvation [GO:0042149]; lipid droplet disassembly [GO:1905691]; lipid storage [GO:0019915]; positive regulation of sequestering of triglyceride [GO:0010890]; vesicle-mediated transport [GO:0016192] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; lipid droplet [GO:0005811]; membrane [GO:0016020]; transport vesicle [GO:0030133] cadherin binding [GO:0045296] 0.56543 0.49672 ELVSSKVSGAQEMVSSAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0495 0 0 0 0 0 0 0 0 0 O60667 FAIM3_HUMAN Fas apoptotic inhibitory molecule 3 (IgM Fc fragment receptor) (Regulator of Fas-induced apoptosis Toso) FCMR FAIM3 TOSO Homo sapiens (Human) cellular defense response [GO:0006968]; immune system process [GO:0002376]; negative regulation of apoptotic process [GO:0043066] extracellular region [GO:0005576]; plasma membrane [GO:0005886] transmembrane signaling receptor activity [GO:0004888] 0.88566 -0.36748 ALDYGSQSGR 8.79766 0 0 0 0 10.147 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60673 REV3L_HUMAN DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Protein reversionless 3-like) (REV3-like) (hREV3) REV3L POLZ REV3 Homo sapiens (Human) DNA-templated DNA replication [GO:0006261]; double-strand break repair via homologous recombination [GO:0000724]; error-prone translesion synthesis [GO:0042276] nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; zeta DNA polymerase complex [GO:0016035] "4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]" 0.96932 -6.1361 ALFHEIANIIK 10.168 0 10.1221 9.96651 0 0 11.7923 11.7404 11.7164 0 0 8.93006 9.58299 9.5675 0 0 0 0 0 10.5105 0 10.2037 10.3116 10.2235 0 9.12182 0 O60674 JAK2_HUMAN Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2) JAK2 Homo sapiens (Human) actin filament polymerization [GO:0030041]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; activation of Janus kinase activity [GO:0042976]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; axon regeneration [GO:0031103]; cell differentiation [GO:0030154]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to interleukin-3 [GO:0036016]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to virus [GO:0098586]; collagen-activated signaling pathway [GO:0038065]; cytokine-mediated signaling pathway [GO:0019221]; enzyme-linked receptor protein signaling pathway [GO:0007167]; erythrocyte differentiation [GO:0030218]; extrinsic apoptotic signaling pathway [GO:0097191]; G protein-coupled receptor signaling pathway [GO:0007186]; granulocyte-macrophage colony-stimulating factor signaling pathway [GO:0038157]; growth hormone receptor signaling pathway [GO:0060396]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; immune response [GO:0006955]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-3-mediated signaling pathway [GO:0038156]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-5-mediated signaling pathway [GO:0038043]; interleukin-6-mediated signaling pathway [GO:0070102]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; mammary gland epithelium development [GO:0061180]; mesoderm development [GO:0007498]; microglial cell activation [GO:0001774]; mineralocorticoid receptor signaling pathway [GO:0031959]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of DNA binding [GO:0043392]; negative regulation of heart contraction [GO:0045822]; negative regulation of neuron apoptotic process [GO:0043524]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial cell apoptotic process [GO:1904037]; positive regulation of growth factor dependent skeletal muscle satellite cell proliferation [GO:1902728]; positive regulation of growth hormone receptor signaling pathway [GO:0060399]; positive regulation of inflammatory response [GO:0050729]; positive regulation of insulin secretion [GO:0032024]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of leukocyte proliferation [GO:0070665]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of platelet activation [GO:0010572]; positive regulation of platelet aggregation [GO:1901731]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 17 type immune response [GO:2000318]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type II interferon production [GO:0032729]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; post-embryonic hemopoiesis [GO:0035166]; post-translational protein modification [GO:0043687]; programmed cell death induced by symbiont [GO:0034050]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of inflammatory response [GO:0050727]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of postsynapse to nucleus signaling pathway [GO:1905539]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; response to amine [GO:0014075]; response to antibiotic [GO:0046677]; response to hydroperoxide [GO:0033194]; response to interleukin-12 [GO:0070671]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; signal transduction [GO:0007165]; transcription by RNA polymerase II [GO:0006366]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; type II interferon-mediated signaling pathway [GO:0060333]; tyrosine phosphorylation of STAT protein [GO:0007260] caveola [GO:0005901]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endosome lumen [GO:0031904]; euchromatin [GO:0000791]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; extrinsic component of plasma membrane [GO:0019897]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; granulocyte macrophage colony-stimulating factor receptor complex [GO:0030526]; interleukin-12 receptor complex [GO:0042022]; interleukin-23 receptor complex [GO:0072536]; membrane raft [GO:0045121]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794] acetylcholine receptor binding [GO:0033130]; ATP binding [GO:0005524]; cytokine receptor binding [GO:0005126]; growth hormone receptor binding [GO:0005131]; heme binding [GO:0020037]; histone binding [GO:0042393]; histone H3Y41 kinase activity [GO:0035401]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; interleukin-12 receptor binding [GO:0005143]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; peptide hormone receptor binding [GO:0051428]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; signaling receptor binding [GO:0005102]; type 1 angiotensin receptor binding [GO:0031702] 0.91342 -0.78598 LSDPGISITVLPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.32107 9.49717 0 0 0 O60678 ANM3_HUMAN Protein arginine N-methyltransferase 3 (EC 2.1.1.319) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3) PRMT3 HRMT1L3 Homo sapiens (Human) "dendritic spine morphogenesis [GO:0060997]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of retinoic acid biosynthetic process [GO:1900053]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; protein methylation [GO:0006479]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] metal ion binding [GO:0046872]; methyltransferase activity [GO:0008168]; modified amino acid binding [GO:0072341]; protein-arginine N-methyltransferase activity [GO:0016274]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]; ribosome binding [GO:0043022] 0.89903 -0.60328 IAFWDDVYGFK 0 0 0 0 0 0 0 0 0 0 0 10.3872 0 0 0 0 0 0 0 0 0 9.94092 0 0 0 0 0 O60701 UGDH_HUMAN UDP-glucose 6-dehydrogenase (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH) (EC 1.1.1.22) UGDH Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate biosynthetic process [GO:0030206]; gastrulation with mouth forming second [GO:0001702]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; neuron development [GO:0048666]; protein hexamerization [GO:0034214]; UDP-glucuronate biosynthetic process [GO:0006065] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] identical protein binding [GO:0042802]; NAD binding [GO:0051287]; UDP-glucose 6-dehydrogenase activity [GO:0003979] 0.011905 1.7137 ELDYERIHK 0 0 9.19638 0 0 0 8.92988 0 0 0 0 0 10.0451 0 0 0 0 0 8.68857 0 0 0 9.57207 9.47565 10.5647 10.6091 10.1205 O60706 ABCC9_HUMAN ATP-binding cassette sub-family C member 9 (Sulfonylurea receptor 2) ABCC9 SUR2 Homo sapiens (Human) cardiac conduction [GO:0061337]; cardiac muscle cell contraction [GO:0086003]; defense response to virus [GO:0051607]; inorganic cation transmembrane transport [GO:0098662]; monoatomic cation transmembrane transport [GO:0098655]; negative regulation of blood pressure [GO:0045776]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1903760]; response to ATP [GO:0033198]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104] inward rectifying potassium channel [GO:0008282]; membrane [GO:0016020]; plasma membrane [GO:0005886]; potassium ion-transporting ATPase complex [GO:0031004]; sarcomere [GO:0030017] ABC-type transporter activity [GO:0140359]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled inorganic anion transmembrane transporter activity [GO:0043225]; ATPase-coupled monoatomic cation transmembrane transporter activity [GO:0019829]; ATPase-coupled transmembrane transporter activity [GO:0042626]; potassium channel activity [GO:0005267]; potassium channel regulator activity [GO:0015459]; sulfonylurea receptor activity [GO:0008281]; transmembrane transporter binding [GO:0044325] 0.95069 -1.4111 FLQDDKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0749 0 0 0 0 0 0 O60716 CTND1_HUMAN Catenin delta-1 (Cadherin-associated Src substrate) (CAS) (p120 catenin) (p120(ctn)) (p120(cas)) CTNND1 KIAA0384 Homo sapiens (Human) brain development [GO:0007420]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cytoplasmic sequestering of protein [GO:0051220]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; protein stabilization [GO:0050821]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; Wnt signaling pathway [GO:0016055] "adherens junction [GO:0005912]; catenin complex [GO:0016342]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density, intracellular component [GO:0099092]; presynaptic active zone cytoplasmic component [GO:0098831]; Schaffer collateral - CA1 synapse [GO:0098685]; zonula adherens [GO:0005915]" beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; protein tyrosine kinase binding [GO:1990782]; signaling receptor binding [GO:0005102] 0.88417 -0.27822 GYELLFQPEVVR 0 0 0 0 0 0 0 0 0 0 0 0 0 12.3054 0 0 0 0 0 0 0 0 0 0 9.6239 8.96677 8.78103 O60721 NCKX1_HUMAN Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger) (Solute carrier family 24 member 1) SLC24A1 KIAA0702 NCKX1 Homo sapiens (Human) calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; intracellular calcium ion homeostasis [GO:0006874]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; monoatomic ion transport [GO:0006811]; potassium ion transmembrane transport [GO:0071805]; response to light intensity [GO:0009642]; sodium ion transmembrane transport [GO:0035725]; visual perception [GO:0007601] cell surface [GO:0009986]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; outer membrane [GO:0019867]; plasma membrane [GO:0005886] "calcium channel activity [GO:0005262]; calcium, potassium:sodium antiporter activity [GO:0008273]; symporter activity [GO:0015293]" 0.6932 0.38441 ILETNSLK 0 0 11.7475 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60729 CC14B_HUMAN Dual specificity protein phosphatase CDC14B (EC 3.1.3.16) (EC 3.1.3.48) (CDC14 cell division cycle 14 homolog B) CDC14B Homo sapiens (Human) cilium assembly [GO:0060271]; DNA repair [GO:0006281]; microtubule cytoskeleton organization [GO:0000226]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; positive regulation of cytokinesis [GO:0032467]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein dephosphorylation [GO:0006470]; regulation of exit from mitosis [GO:0007096] centrosome [GO:0005813]; mitotic spindle [GO:0072686]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922] myosin phosphatase activity [GO:0017018]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138] 0.96217 -2.5395 GQENGQHRAAFSK 0 0 0 0 0 0 0 0 0 0 11.0395 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60733 PLPL9_HUMAN 85/88 kDa calcium-independent phospholipase A2 (CaI-PLA2) (EC 3.1.1.4) (2-lysophosphatidylcholine acylhydrolase) (EC 3.1.1.5) (Group VI phospholipase A2) (GVI PLA2) (Intracellular membrane-associated calcium-independent phospholipase A2 beta) (iPLA2-beta) (Palmitoyl-CoA hydrolase) (EC 3.1.2.2) (Patatin-like phospholipase domain-containing protein 9) (PNPLA9) PLA2G6 PLPLA9 Homo sapiens (Human) "antibacterial humoral response [GO:0019731]; cardiolipin acyl-chain remodeling [GO:0035965]; cardiolipin biosynthetic process [GO:0032049]; chemotaxis [GO:0006935]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; maternal process involved in female pregnancy [GO:0060135]; memory [GO:0007613]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; phosphatidic acid metabolic process [GO:0046473]; phosphatidylcholine catabolic process [GO:0034638]; phosphatidylethanolamine catabolic process [GO:0046338]; platelet activating factor metabolic process [GO:0046469]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of exocytosis [GO:0045921]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; regulation of store-operated calcium channel activity [GO:1901339]; response to endoplasmic reticulum stress [GO:0034976]; urinary bladder smooth muscle contraction [GO:0014832]; vasodilation [GO:0042311]" centriolar satellite [GO:0034451]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143] 1-alkyl-2-acetylglycerophosphocholine esterase activity [GO:0003847]; ATP-dependent protein binding [GO:0043008]; calcium-independent phospholipase A2 activity [GO:0047499]; calmodulin binding [GO:0005516]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; lysophospholipase activity [GO:0004622]; myristoyl-CoA hydrolase activity [GO:0102991]; palmitoyl-CoA hydrolase activity [GO:0016290]; phosphatidyl phospholipase B activity [GO:0102545]; phospholipase A2 activity [GO:0004623]; protein kinase binding [GO:0019901]; serine hydrolase activity [GO:0017171] 0.95452 -1.511 ELGKMVVDCCTDPDGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.45348 0 0 0 0 11.5369 0 0 O60741 HCN1_HUMAN Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) HCN1 BCNG1 Homo sapiens (Human) "apical protein localization [GO:0045176]; cellular response to cAMP [GO:0071320]; general adaptation syndrome, behavioral process [GO:0051867]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; potassium ion transmembrane transport [GO:0071805]; protein homotetramerization [GO:0051289]; regulation of cation channel activity [GO:2001257]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of membrane depolarization [GO:0003254]; regulation of membrane potential [GO:0042391]; regulation of SA node cell action potential [GO:0098907]; retinal cone cell development [GO:0046549]; sodium ion transmembrane transport [GO:0035725]" axon [GO:0030424]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; HCN channel complex [GO:0098855]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic active zone membrane [GO:0048787] cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; intracellular cAMP-activated cation channel activity [GO:0005222]; intracellular cAMP-activated cation channel activity involved in regulation of presynaptic membrane potential [GO:0140232]; potassium channel activity [GO:0005267]; voltage-gated monoatomic cation channel activity [GO:0022843]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated sodium channel activity [GO:0005248] 0.93885 -1.3204 STVPQRVTLFR 0 0 0 0 0 0 0 8.73162 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60749 SNX2_HUMAN Sorting nexin-2 (Transformation-related gene 9 protein) (TRG-9) SNX2 TRG9 Homo sapiens (Human) "early endosome to Golgi transport [GO:0034498]; intracellular protein transport [GO:0006886]; lamellipodium morphogenesis [GO:0072673]; retrograde transport, endosome to Golgi [GO:0042147]" "cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; endosome membrane [GO:0010008]; lamellipodium [GO:0030027]; lysosome [GO:0005764]; membrane [GO:0016020]; protein-containing complex [GO:0032991]; retromer complex [GO:0030904]; retromer, tubulation complex [GO:0030905]" cadherin binding [GO:0045296]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; leptin receptor binding [GO:1990460]; phosphatidylinositol binding [GO:0035091]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; transferrin receptor binding [GO:1990459] 0.96812 -3.8276 AADAVNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.6632 0 0 0 11.2267 0 0 O60756 BCE1_HUMAN Putative protein BCE-1 BCE1 Homo sapiens (Human) 0.9166 -0.76777 SFTKQGQQRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4942 0 0 0 0 0 0 0 0 0 0 O60759 CYTIP_HUMAN Cytohesin-interacting protein (Cytohesin binder and regulator) (CYBR) (Cytohesin-associated scaffolding protein) (CASP) (Cytohesin-binding protein HE) (Cbp HE) (Pleckstrin homology Sec7 and coiled-coil domains-binding protein) CYTIP PSCDBP Homo sapiens (Human) regulation of cell adhesion [GO:0030155] cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; nucleoplasm [GO:0005654] 0.47869 0.62479 RIQMLADTVATLPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8139 0 0 O60762 DPM1_HUMAN Dolichol-phosphate mannosyltransferase subunit 1 (EC 2.4.1.83) (Dolichol-phosphate mannose synthase subunit 1) (DPM synthase subunit 1) (Dolichyl-phosphate beta-D-mannosyltransferase subunit 1) (Mannose-P-dolichol synthase subunit 1) (MPD synthase subunit 1) DPM1 Homo sapiens (Human) dolichol metabolic process [GO:0019348]; dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; GDP-mannose metabolic process [GO:0019673]; GPI anchor biosynthetic process [GO:0006506]; protein mannosylation [GO:0035268]; protein N-linked glycosylation via asparagine [GO:0018279]; protein O-linked mannosylation [GO:0035269] dolichol-phosphate-mannose synthase complex [GO:0033185]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; nucleus [GO:0005634] alcohol binding [GO:0043178]; dolichyl-phosphate beta-D-mannosyltransferase activity [GO:0004582]; dolichyl-phosphate-mannose-protein mannosyltransferase activity [GO:0004169]; mannose binding [GO:0005537]; metal ion binding [GO:0046872] 0.84057 0.18386 DVAEQLEK 0 0 0 0 0 0 0 0 0 0 0 9.12443 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60763 USO1_HUMAN General vesicular transport factor p115 (Protein USO1 homolog) (Transcytosis-associated protein) (TAP) (Vesicle-docking protein) USO1 VDP Homo sapiens (Human) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi vesicle docking [GO:0048211]; intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]; regulation of cellular response to insulin stimulus [GO:1900076]; secretory granule localization [GO:0032252]; small GTPase mediated signal transduction [GO:0007264]; transcytosis [GO:0045056]; vesicle fusion with Golgi apparatus [GO:0048280] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; ER to Golgi transport vesicle membrane [GO:0012507]; fibrillar center [GO:0001650]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; perinuclear region of cytoplasm [GO:0048471]; transport vesicle [GO:0030133] cadherin binding [GO:0045296]; RNA binding [GO:0003723] 0.89737 -0.67067 IGKENFIEKLGFISK 0 12.1678 0 0 0 0 0 0 0 0 0 0 9.35229 14.6342 0 0 0 0 12.8266 0 0 0 0 0 0 0 0 O60765 Z354A_HUMAN Zinc finger protein 354A (Transcription factor 17) (TCF-17) (Zinc finger protein eZNF) ZNF354A EZNF HKL1 TCF17 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357]; sensory perception of sound [GO:0007605] cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.60509 0.43683 ECGKSFSRR 9.9993 0 0 0 0 0 0 0 10.8677 0 10.5981 0 0 0 0 0 0 0 0 0 0 0 0 10.9804 0 0 0 O60784 TOM1_HUMAN Target of Myb1 membrane trafficking protein (Target of Myb protein 1) TOM1 Homo sapiens (Human) autophagosome-lysosome fusion [GO:0061909]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; positive regulation of autophagosome maturation [GO:1901098]; protein transport [GO:0015031]; regulation of endosome organization [GO:1904978]; signal transduction [GO:0007165]; substrate localization to autophagosome [GO:0061753] azurophil granule membrane [GO:0035577]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579] clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; myosin VI binding [GO:0070853]; phosphatidylinositol-5-phosphate binding [GO:0010314]; polyubiquitin modification-dependent protein binding [GO:0031593]; ubiquitin binding [GO:0043130] 0.95901 -1.7036 GVTSEEFDK 0 0 0 0 0 0 0 0 8.14659 0 0 8.64573 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60812 HNRC1_HUMAN Heterogeneous nuclear ribonucleoprotein C-like 1 (hnRNP C-like-1) (hnRNP core protein C-like 1) HNRNPCL1 HNRPCL1 Homo sapiens (Human) nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] identical protein binding [GO:0042802]; RNA binding [GO:0003723] 0.89069 -0.48102 DYYDGMYSFPAR 9.65211 9.66851 9.41117 0 0 0 9.79256 9.95915 10.0745 0 9.12915 10.2527 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60813 PRA11_HUMAN PRAME family member 11 PRAMEF11 Homo sapiens (Human) negative regulation of apoptotic process [GO:0043066]; negative regulation of cell differentiation [GO:0045596]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of cell population proliferation [GO:0008284] cytoplasm [GO:0005737] 0.94685 -1.3511 HLRHPKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.756 0 0 11.5469 0 0 0 0 O60825 F262_HUMAN "6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (6PF-2-K/Fru-2,6-P2ase 2) (PFK/FBPase 2) (6PF-2-K/Fru-2,6-P2ase heart-type isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]" PFKFB2 Homo sapiens (Human) "fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]; glucose catabolic process [GO:0006007]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; positive regulation of glucokinase activity [GO:0033133]; positive regulation of insulin secretion [GO:0032024]; response to glucose [GO:0009749]" cytosol [GO:0005829]; nucleoplasm [GO:0005654] "6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]; protein kinase binding [GO:0019901]" 0.92394 -1.1696 IVYYLMNIHVQPR 0 0 0 0 11.8091 0 0 0 0 0 0 0 0 0 0 0 0 12.0905 0 0 0 0 0 0 0 0 0 O60832 DKC1_HUMAN H/ACA ribonucleoprotein complex subunit DKC1 (EC 5.4.99.-) (CBF5 homolog) (Dyskerin) (Nopp140-associated protein of 57 kDa) (Nucleolar protein NAP57) (Nucleolar protein family A member 4) (snoRNP protein DKC1) DKC1 NOLA4 Homo sapiens (Human) box H/ACA RNA 3'-end processing [GO:0000495]; enzyme-directed rRNA pseudouridine synthesis [GO:0000455]; mRNA pseudouridine synthesis [GO:1990481]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of protein localization to Cajal body [GO:1904871]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of telomerase RNA localization to Cajal body [GO:1904872]; RNA processing [GO:0006396]; rRNA processing [GO:0006364]; rRNA pseudouridine synthesis [GO:0031118]; scaRNA localization to Cajal body [GO:0090666]; snRNA pseudouridine synthesis [GO:0031120]; telomerase RNA stabilization [GO:0090669]; telomere maintenance via telomerase [GO:0007004] box H/ACA scaRNP complex [GO:0072589]; box H/ACA snoRNP complex [GO:0031429]; box H/ACA telomerase RNP complex [GO:0090661]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; telomerase holoenzyme complex [GO:0005697] box H/ACA snoRNA binding [GO:0034513]; pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723]; telomerase activity [GO:0003720]; telomerase RNA binding [GO:0070034] 0.88486 -0.33147 AKEVELVSE 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0579 O60840 CAC1F_HUMAN Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage-gated calcium channel subunit alpha Cav1.4) CACNA1F CACNAF1 Homo sapiens (Human) calcium ion import across plasma membrane [GO:0098703]; detection of light stimulus involved in visual perception [GO:0050908]; negative regulation of voltage-gated calcium channel activity [GO:1901386]; regulation of monoatomic ion transmembrane transport [GO:0034765]; visual perception [GO:0007601] membrane [GO:0016020]; perikaryon [GO:0043204]; photoreceptor outer segment [GO:0001750]; voltage-gated calcium channel complex [GO:0005891] high voltage-gated calcium channel activity [GO:0008331]; metal ion binding [GO:0046872]; voltage-gated calcium channel activity [GO:0005245] 0.96736 -2.805 ANRVLRAR 11.8638 11.9519 0 0 0 11.5569 11.4273 0 11.7342 0 0 11.8436 0 10.3173 0 0 10.1694 10.7745 0 0 0 0 0 0 0 0 0 O60841 IF2P_HUMAN Eukaryotic translation initiation factor 5B (eIF-5B) (EC 3.6.5.3) (Translation initiation factor IF-2) EIF5B IF2 KIAA0741 Homo sapiens (Human) regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413] cytoplasm [GO:0005737]; cytosol [GO:0005829]; synapse [GO:0045202] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; translation initiation factor activity [GO:0003743] 0.96304 -2.6578 DPIVMGVTVEAGQVKQGTPMCVPSK 9.23747 0 9.84853 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60858 TRI13_HUMAN E3 ubiquitin-protein ligase TRIM13 (EC 2.3.2.27) (B-cell chronic lymphocytic leukemia tumor suppressor Leu5) (Leukemia-associated protein 5) (Putative tumor suppressor RFP2) (RING finger protein 77) (RING-type E3 ubiquitin transferase TRIM13) (Ret finger protein 2) (Tripartite motif-containing protein 13) TRIM13 LEU5 RFP2 RNF77 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; endoplasmic reticulum mannose trimming [GO:1904380]; innate immune response [GO:0045087]; negative regulation of viral transcription [GO:0032897]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; suppression of viral release by host [GO:0044790]; ubiquitin-dependent ERAD pathway [GO:0030433] cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum quality control compartment [GO:0044322]; perinuclear endoplasmic reticulum [GO:0097038] transcription coactivator activity [GO:0003713]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-like protein ligase activity [GO:0061659]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.96904 -6.6931 IPWSFYK 0 0 0 0 0 0 0 0 9.31268 0 0 0 0 0 0 0 0 10.5155 0 0 8.9183 0 0 0 0 0 0 O60861 GAS7_HUMAN Growth arrest-specific protein 7 (GAS-7) GAS7 KIAA0394 Homo sapiens (Human) actin filament polymerization [GO:0030041]; neuron projection morphogenesis [GO:0048812] actin filament [GO:0005884]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886] actin filament binding [GO:0051015]; identical protein binding [GO:0042802] 0.97 -3.0806 ENFKKDMK 0 11.4915 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.9497 0 0 9.51341 9.61038 0 0 0 O60869 EDF1_HUMAN Endothelial differentiation-related factor 1 (EDF-1) (Multiprotein-bridging factor 1) (MBF1) EDF1 Homo sapiens (Human) endothelial cell differentiation [GO:0045446]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription [GO:0006355]; regulation of lipid metabolic process [GO:0019216] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] calmodulin binding [GO:0005516]; DNA binding [GO:0003677]; RNA binding [GO:0003723]; TFIID-class transcription factor complex binding [GO:0001094]; transcription coactivator activity [GO:0003713] 0.33715 0.77255 AESDWDTVTVLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.69014 0 0 0 0 0 0 0 0 0 0 0 0 O60870 KIN17_HUMAN "DNA/RNA-binding protein KIN17 (Binding to curved DNA) (KIN, antigenic determinant of recA protein homolog)" KIN BTCD KIN17 Homo sapiens (Human) DNA damage response [GO:0006974]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; mRNA processing [GO:0006397] cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; metal ion binding [GO:0046872]; RNA binding [GO:0003723] 0.8992 -0.66408 KAIVKEVIDK 12.9407 0 0 10.3026 0 0 0 0 0 0 8.59347 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60879 DIAP2_HUMAN Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) DIAPH2 DIA Homo sapiens (Human) actin filament polymerization [GO:0030041]; female gamete generation [GO:0007292]; oogenesis [GO:0048477] actin filament [GO:0005884]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; nucleolus [GO:0005730] actin binding [GO:0003779]; signaling receptor binding [GO:0005102]; small GTPase binding [GO:0031267] 0.88242 -0.077648 NKDFTTKR 9.33771 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.6754 0 0 0 0 0 0 0 0 0 0 0 O60882 MMP20_HUMAN Matrix metalloproteinase-20 (MMP-20) (EC 3.4.24.-) (Enamel metalloproteinase) (Enamelysin) MMP20 Homo sapiens (Human) amelogenesis [GO:0097186]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of enamel mineralization [GO:0070173] extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270] 0.91557 -0.7638 EGHQIGEMVARGSNSMIR 0 0 0 0 0 0 0 0 0 10.6003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60884 DNJA2_HUMAN DnaJ homolog subfamily A member 2 (Cell cycle progression restoration gene 3 protein) (Dnj3) (Dj3) (HIRA-interacting protein 4) (Renal carcinoma antigen NY-REN-14) DNAJA2 CPR3 HIRIP4 Homo sapiens (Human) positive regulation of cell population proliferation [GO:0008284]; protein refolding [GO:0042026]; response to heat [GO:0009408] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020] ATP binding [GO:0005524]; ATPase activator activity [GO:0001671]; Hsp70 protein binding [GO:0030544]; metal ion binding [GO:0046872]; protein-folding chaperone binding [GO:0051087]; unfolded protein binding [GO:0051082] 0.75644 0.30568 GEDMMHPLK 0 0 0 0 0 0 0 0 0 0 9.75261 0 0 0 0 10.7038 9.94059 0 0 0 0 0 0 0 0 0 0 O60888 CUTA_HUMAN Protein CutA (Acetylcholinesterase-associated protein) (Brain acetylcholinesterase putative membrane anchor) CUTA ACHAP C6orf82 Homo sapiens (Human) protein localization [GO:0008104]; response to metal ion [GO:0010038] extracellular exosome [GO:0070062]; membrane [GO:0016020] copper ion binding [GO:0005507]; enzyme binding [GO:0019899] 0.0077519 2.0375 QVTESVSDSITVLP 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.95147 0 0 0 0 0 0 O60890 OPHN1_HUMAN Oligophrenin-1 OPHN1 Homo sapiens (Human) "actin cytoskeleton organization [GO:0030036]; axon guidance [GO:0007411]; cell junction assembly [GO:0034329]; cell morphogenesis involved in neuron differentiation [GO:0048667]; cerebellar granule cell differentiation [GO:0021707]; cerebral cortex neuron differentiation [GO:0021895]; establishment of epithelial cell apical/basal polarity [GO:0045198]; maintenance of postsynaptic specialization structure [GO:0098880]; negative regulation of proteasomal protein catabolic process [GO:1901799]; nervous system development [GO:0007399]; neuron differentiation [GO:0030182]; neuron projection development [GO:0031175]; regulation of endocytosis [GO:0030100]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of Rho protein signal transduction [GO:0035023]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle endocytosis [GO:1900242]; signal transduction [GO:0007165]; substrate-dependent cell migration, cell extension [GO:0006930]; synaptic vesicle endocytosis [GO:0048488]" actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; terminal bouton [GO:0043195] actin binding [GO:0003779]; GTPase activator activity [GO:0005096]; ionotropic glutamate receptor binding [GO:0035255]; phospholipid binding [GO:0005543] 0.87699 0.019807 FYSLLDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.65882 0 0 0 0 0 0 0 0 O60902 SHOX2_HUMAN Short stature homeobox protein 2 (Homeobox protein Og12X) (Paired-related homeobox protein SHOT) SHOX2 OG12X SHOT Homo sapiens (Human) cardiac pacemaker cell differentiation [GO:0060920]; cardiac right atrium morphogenesis [GO:0003213]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; chondrocyte development [GO:0002063]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic forelimb morphogenesis [GO:0035115]; embryonic skeletal joint morphogenesis [GO:0060272]; mesenchymal cell proliferation [GO:0010463]; muscle tissue morphogenesis [GO:0060415]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; osteoblast differentiation [GO:0001649]; positive regulation of axonogenesis [GO:0050772]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of skeletal muscle fiber development [GO:0048743]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of stem cell proliferation [GO:2000648]; regulation of branching morphogenesis of a nerve [GO:2000172]; regulation of chondrocyte differentiation [GO:0032330]; regulation of heart rate [GO:0002027]; regulation of transcription by RNA polymerase II [GO:0006357]; sinoatrial node cell development [GO:0060931]; sinoatrial node development [GO:0003163]; sinoatrial valve development [GO:0003172]; skeletal system development [GO:0001501]; smoothened signaling pathway [GO:0007224]; stem cell proliferation [GO:0072089] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.88477 -0.2133 EPGSPRLTEVSPELK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9257 0 0 0 0 0 0 0 0 0 0 O60909 B4GT2_HUMAN "Beta-1,4-galactosyltransferase 2 (Beta-1,4-GalTase 2) (Beta4Gal-T2) (b4Gal-T2) (EC 2.4.1.-) (Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase) (Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase) (EC 2.4.1.38) (Lactose synthase A protein) (EC 2.4.1.22) (N-acetyllactosamine synthase) (EC 2.4.1.90) (Nal synthase) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 2) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 2)" B4GALT2 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; cerebellar Purkinje cell layer development [GO:0021680]; locomotory behavior [GO:0007626]; memory [GO:0007613]; protein glycosylation [GO:0006486]; visual learning [GO:0008542] Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654] "beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; metal ion binding [GO:0046872]; N-acetyllactosamine synthase activity [GO:0003945]" 0.91322 -0.75705 DGIGSVRYQVLEVSR 10.3744 10.2973 10.2765 0 9.57219 9.59348 0 0 10.2167 0 11.4562 11.4864 10.0526 10.1675 11.6948 10.7276 10.5717 10.0928 0 0 0 0 0 0 0 0 0 O60911 CATL2_HUMAN Cathepsin L2 (EC 3.4.22.43) (Cathepsin U) (Cathepsin V) CTSV CATL2 CTSL2 CTSU UNQ268/PRO305 Homo sapiens (Human) antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of peptidase activity [GO:0010952]; proteolysis involved in protein catabolic process [GO:0051603] extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202] cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; serine-type endopeptidase activity [GO:0004252] 0.95366 -1.5246 GYVTPVKNQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.37686 0 0 O60921 HUS1_HUMAN Checkpoint protein HUS1 (hHUS1) HUS1 Homo sapiens (Human) cellular response to ionizing radiation [GO:0071479]; DNA damage checkpoint signaling [GO:0000077]; DNA damage response [GO:0006974]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; embryo development ending in birth or egg hatching [GO:0009792]; meiotic DNA integrity checkpoint signaling [GO:0044778]; mitotic DNA replication checkpoint signaling [GO:0033314]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; nucleotide-excision repair [GO:0006289]; protein phosphorylation [GO:0006468]; regulation of protein phosphorylation [GO:0001932]; response to UV [GO:0009411]; telomere maintenance [GO:0000723] checkpoint clamp complex [GO:0030896]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861] 0.55838 0.53976 ISNMIAK 0 0 0 0 0 0 0 0 0 0 9.26339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60927 PP1RB_HUMAN E3 ubiquitin-protein ligase PPP1R11 (EC 2.3.2.27) (Hemochromatosis candidate gene V protein) (HCG V) (Protein phosphatase 1 regulatory subunit 11) (Protein phosphatase inhibitor 3) PPP1R11 HCGV TCTE5 Homo sapiens (Human) defense response to Gram-positive bacterium [GO:0050830]; negative regulation of cytokine production [GO:0001818]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737]; nucleus [GO:0005634] molecular function inhibitor activity [GO:0140678]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase inhibitor activity [GO:0004865]; ubiquitin protein ligase activity [GO:0061630] 0.94668 -1.3574 SLTIKLR 0 0 9.00138 0 0 0 0 8.83807 0 0 0 0 0 0 8.5457 0 0 0 0 0 0 0 0 0 0 0 0 O60930 RNH1_HUMAN Ribonuclease H1 (RNase H1) (EC 3.1.26.4) (Ribonuclease H type II) RNASEH1 RNH1 Homo sapiens (Human) "DNA replication, removal of RNA primer [GO:0043137]; RNA catabolic process [GO:0006401]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]" cytoplasm [GO:0005737] magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA binding [GO:0003723]; RNA nuclease activity [GO:0004540]; RNA-DNA hybrid ribonuclease activity [GO:0004523] 0.95936 -1.8778 EVINKEDFVALER 0 11.1239 0 9.81283 9.06431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3413 0 O60934 NBN_HUMAN Nibrin (Cell cycle regulatory protein p95) (Nijmegen breakage syndrome protein 1) NBN NBS NBS1 P95 Homo sapiens (Human) "blastocyst growth [GO:0001832]; DNA damage checkpoint signaling [GO:0000077]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA double-strand break processing [GO:0000729]; DNA duplex unwinding [GO:0032508]; DNA strand resection involved in replication fork processing [GO:0110025]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; homologous recombination [GO:0035825]; intrinsic apoptotic signaling pathway [GO:0097193]; isotype switching [GO:0045190]; meiotic cell cycle [GO:0051321]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; mitotic G2/M transition checkpoint [GO:0044818]; negative regulation of telomere capping [GO:1904354]; neuroblast proliferation [GO:0007405]; neuromuscular process controlling balance [GO:0050885]; positive regulation of kinase activity [GO:0033674]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of telomere maintenance [GO:0032206]; regulation of cell cycle [GO:0051726]; regulation of DNA-templated DNA replication initiation [GO:0030174]; t-circle formation [GO:0090656]; telomere maintenance [GO:0000723]; telomere maintenance via telomere trimming [GO:0090737]; telomeric 3' overhang formation [GO:0031860]" "BRCA1-C complex [GO:0070533]; chromosomal region [GO:0098687]; chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Mre11 complex [GO:0030870]; nuclear inclusion body [GO:0042405]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]" damaged DNA binding [GO:0003684]; DNA-binding transcription factor binding [GO:0140297] 0.72732 0.34294 ISQENEIGK 0 0 0 0 0 0 0 8.41819 0 0 0 0 0 9.33586 0 0 0 0 0 0 0 0 0 0 0 9.88004 0 O60936 NOL3_HUMAN Nucleolar protein 3 (Apoptosis repressor with CARD) (Muscle-enriched cytoplasmic protein) (Myp) (Nucleolar protein of 30 kDa) (Nop30) NOL3 ARC NOP Homo sapiens (Human) inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; mRNA splice site selection [GO:0006376]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; protein complex oligomerization [GO:0051259]; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0014808]; RNA splicing [GO:0008380] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; sarcoplasmic reticulum [GO:0016529] calcium ion binding [GO:0005509]; caspase binding [GO:0089720]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; RNA binding [GO:0003723] 0.61187 0.42883 GVLTGPEYEALDALPDAER 0 0 10.2538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60938 KERA_HUMAN Keratocan (KTN) (Keratan sulfate proteoglycan keratocan) KERA SLRR2B Homo sapiens (Human) cornea development in camera-type eye [GO:0061303]; response to stimulus [GO:0050896]; visual perception [GO:0007601] extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; lysosomal lumen [GO:0043202] 0.84884 0.11419 EIPAIPSR 9.9976 0 0 0 0 0 0 0 0 0 9.09252 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O60942 MCE1_HUMAN mRNA-capping enzyme (HCAP1) (HCE) [Includes: mRNA 5'-triphosphate monophosphatase (EC 3.6.1.74) (mRNA 5'-phosphatase); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)] RNGTT CAP1A Homo sapiens (Human) 7-methylguanosine mRNA capping [GO:0006370]; protein dephosphorylation [GO:0006470]; RNA processing [GO:0006396] nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; GTP binding [GO:0005525]; inorganic triphosphate phosphatase activity [GO:0050355]; mRNA 5'-phosphatase activity [GO:0140818]; mRNA guanylyltransferase activity [GO:0004484]; polynucleotide 5'-phosphatase activity [GO:0004651]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; RNA guanylyltransferase activity [GO:0008192] 0.95198 -1.393 FHPSMLSNYLKSLKVK 0 0 0 8.38733 0 0 0 0 13.3399 0 0 10.1737 0 0 0 0 0 0 0 10.1075 0 0 0 0 0 0 0 O75015 FCG3B_HUMAN Low affinity immunoglobulin gamma Fc region receptor III-B (Fc-gamma RIII-beta) (CD16-I) (Fc-gamma RIII) (Fc-gamma RIIIb) (FcRIII) (FcRIIIb) (FcR-10) (IgG Fc receptor III-1) (CD antigen CD16b) FCGR3B CD16B FCG3 FCGR3 IGFR3 Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; immune response [GO:0006955]; regulation of immune response [GO:0050776] extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667] GPI anchor binding [GO:0034235]; IgG binding [GO:0019864]; transmembrane signaling receptor activity [GO:0004888] 0.88413 -0.12709 DRKYFHHNSDFHIPK 0 0 0 9.5803 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75019 LIRA1_HUMAN Leukocyte immunoglobulin-like receptor subfamily A member 1 (CD85 antigen-like family member I) (Leukocyte immunoglobulin-like receptor 6) (LIR-6) (CD antigen CD85i) LILRA1 LIR6 Homo sapiens (Human) adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952] plasma membrane [GO:0005886] antigen binding [GO:0003823]; inhibitory MHC class I receptor activity [GO:0032396]; transmembrane signaling receptor activity [GO:0004888] 0.88187 -0.30951 AGAADAPLRLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2568 O75022 LIRB3_HUMAN Leukocyte immunoglobulin-like receptor subfamily B member 3 (LIR-3) (Leukocyte immunoglobulin-like receptor 3) (CD85 antigen-like family member A) (Immunoglobulin-like transcript 5) (ILT-5) (Monocyte inhibitory receptor HL9) (CD antigen CD85a) LILRB3 ILT5 LIR3 Homo sapiens (Human) adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; defense response [GO:0006952]; negative regulation of osteoclast differentiation [GO:0045671] plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667] signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888] 0.86869 0.045545 EGSPEPLDR 0 0 11.5733 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75027 ABCB7_HUMAN "Iron-sulfur clusters transporter ABCB7, mitochondrial (ATP-binding cassette sub-family B member 7, mitochondrial) (ATP-binding cassette transporter 7) (ABC transporter 7 protein)" ABCB7 ABC7 Homo sapiens (Human) intracellular iron ion homeostasis [GO:0006879]; iron ion transmembrane transport [GO:0034755]; iron-sulfur cluster assembly [GO:0016226]; iron-sulfur cluster export from the mitochondrion [GO:0140466]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; positive regulation of heme biosynthetic process [GO:0070455]; positive regulation of iron-sulfur cluster assembly [GO:1903331]; transmembrane transport [GO:0055085] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] ABC-type iron-sulfur cluster transporter activity [GO:0140481]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]; heme transmembrane transporter activity [GO:0015232]; protein homodimerization activity [GO:0042803] 0.89898 -0.57354 LQEEIVNSVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.6851 0 0 O75031 HSF2B_HUMAN Heat shock factor 2-binding protein HSF2BP MEILB2 Homo sapiens (Human) double-strand break repair involved in meiotic recombination [GO:1990918]; female meiosis I [GO:0007144]; male meiosis I [GO:0007141]; spermatogenesis [GO:0007283]; transcription by RNA polymerase II [GO:0006366] chromosome [GO:0005694]; cytosol [GO:0005829] 0.8844 -0.1449 EQELEQLKMDCEHFKAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.08292 0 0 0 O75037 KI21B_HUMAN Kinesin-like protein KIF21B KIF21B KIAA0449 Homo sapiens (Human) microtubule-based movement [GO:0007018] cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; growth cone [GO:0030426]; kinesin complex [GO:0005871]; microtubule [GO:0005874] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777] 0.95066 -1.4178 EELFLLQEALR 13.6133 0 0 0 0 0 0 0 0 10.6359 0 11.4519 0 0 0 0 0 0 0 9.50696 0 0 9.33385 0 9.61532 0 0 O75038 PLCH2_HUMAN "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-eta-2) (Phosphoinositide phospholipase C-like 4) (PLC-L4) (Phospholipase C-like protein 4) (Phospholipase C-eta-2) (PLC-eta2)" PLCH2 KIAA0450 PLCL4 Homo sapiens (Human) lipid catabolic process [GO:0016042]; phosphatidylinositol metabolic process [GO:0046488]; phosphatidylinositol-mediated signaling [GO:0048015]; release of sequestered calcium ion into cytosol [GO:0051209] cytoplasm [GO:0005737]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; phosphatidylinositol phospholipase C activity [GO:0004435] 0.96854 -8.6177 ISIDSIQEVSEGR 0 0 0 0 0 0 0 0 0 0 0 0 9.06215 8.41215 0 0 0 0 0 0 0 0 9.3269 0 9.55204 10.8922 0 O75044 SRGP2_HUMAN SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2) (Rho GTPase-activating protein 34) SRGAP2 ARHGAP34 FNBP2 KIAA0456 SRGAP2A Homo sapiens (Human) actin filament severing [GO:0051014]; dendritic spine development [GO:0060996]; excitatory synapse assembly [GO:1904861]; extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration [GO:0021816]; filopodium assembly [GO:0046847]; inhibitory synapse assembly [GO:1904862]; lamellipodium assembly involved in ameboidal cell migration [GO:0003363]; negative regulation of cell migration [GO:0030336]; negative regulation of neuron migration [GO:2001223]; neuron projection morphogenesis [GO:0048812]; positive regulation of GTPase activity [GO:0043547]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; substrate adhesion-dependent cell spreading [GO:0034446] cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine head [GO:0044327]; lamellipodium [GO:0030027]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211] GTPase activator activity [GO:0005096]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; small GTPase binding [GO:0031267] 0.95905 -1.7125 ELERQSSVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.43798 0 O75051 PLXA2_HUMAN Plexin-A2 (Semaphorin receptor OCT) PLXNA2 KIAA0463 OCT PLXN2 UNQ209/PRO235 Homo sapiens (Human) centrosome localization [GO:0051642]; cerebellar granule cell precursor tangential migration [GO:0021935]; limb bud formation [GO:0060174]; negative regulation of cell adhesion [GO:0007162]; neural tube development [GO:0021915]; pharyngeal system development [GO:0060037]; positive regulation of axonogenesis [GO:0050772]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; somitogenesis [GO:0001756] plasma membrane [GO:0005886]; semaphorin receptor complex [GO:0002116] identical protein binding [GO:0042802]; semaphorin receptor activity [GO:0017154] 0.9244 -0.95329 APMITPDLESGVK 0 0 0 0 0 0 0 10.1936 0 0 0 0 0 0 0 9.23132 0 9.25101 0 0 10.079 0 0 0 0 10.7372 0 O75054 IGSF3_HUMAN Immunoglobulin superfamily member 3 (IgSF3) (Glu-Trp-Ile EWI motif-containing protein 3) (EWI-3) IGSF3 EWI3 KIAA0466 Homo sapiens (Human) lacrimal gland development [GO:0032808] cell surface [GO:0009986]; membrane [GO:0016020] 0.95927 -1.9516 KEDEGQYECHVTEWVR 14.7166 0 0 8.91907 10.6264 0 0 11.1313 0 0 10.7699 0 0 0 0 0 0 0 0 0 8.98638 0 0 0 0 11.0109 0 O75061 AUXI_HUMAN Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6) DNAJC6 KIAA0473 Homo sapiens (Human) clathrin-dependent endocytosis [GO:0072583]; dephosphorylation [GO:0016311]; regulation of clathrin-dependent endocytosis [GO:2000369]; synaptic vesicle uncoating [GO:0016191] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of presynaptic endocytic zone membrane [GO:0098894]; intracellular membrane-bounded organelle [GO:0043231]; postsynaptic density [GO:0014069]; vesicle [GO:0031982] clathrin binding [GO:0030276]; protein tyrosine phosphatase activity [GO:0004725]; SH3 domain binding [GO:0017124] 0.889 -0.42727 ILEWIEGK 10.1653 0 10.1106 0 0 0 0 0 0 11.5646 12.1807 11.4519 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75063 XYLK_HUMAN Glycosaminoglycan xylosylkinase (EC 2.7.1.-) (Xylose kinase) FAM20B KIAA0475 Homo sapiens (Human) phosphorylation [GO:0016310]; proteoglycan biosynthetic process [GO:0030166] Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654] "ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; phosphotransferase activity, alcohol group as acceptor [GO:0016773]" 0.78394 0.25309 SFGNPSLDER 9.54311 9.27903 8.87427 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75064 DEN4B_HUMAN DENN domain-containing protein 4B DENND4B KIAA0476 Homo sapiens (Human) regulation of Rab protein signal transduction [GO:0032483] cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654] guanyl-nucleotide exchange factor activity [GO:0005085] 0.88298 -0.076301 VAQRMAQKSAAVPELWAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4605 0 0 0 0 0 0 O75069 TMCC2_HUMAN Transmembrane and coiled-coil domains protein 2 (Cerebral protein 11) TMCC2 KIAA0481 hucep-11 Homo sapiens (Human) amyloid precursor protein metabolic process [GO:0042982] endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789] 0.83555 0.19069 VAYQSYER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.62565 0 0 0 0 0 10.6716 O75077 ADA23_HUMAN "Disintegrin and metalloproteinase domain-containing protein 23 (ADAM 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3)" ADAM23 MDC3 Homo sapiens (Human) cell adhesion [GO:0007155]; cellular response to leukemia inhibitory factor [GO:1990830]; central nervous system development [GO:0007417]; proteolysis [GO:0006508] extracellular region [GO:0005576]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734] integrin binding [GO:0005178]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237] 0.96462 -2.6937 HQQKHNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2029 0 0 0 0 0 0 0 0 0 0 0 0 O75078 ADA11_HUMAN "Disintegrin and metalloproteinase domain-containing protein 11 (ADAM 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC)" ADAM11 MDC Homo sapiens (Human) behavioral response to acetic acid induced pain [GO:0061367]; behavioral response to formalin induced pain [GO:0061368]; establishment of protein localization [GO:0045184]; integrin-mediated signaling pathway [GO:0007229]; multicellular organismal response to stress [GO:0033555]; proteolysis [GO:0006508] axon [GO:0030424]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734] integrin binding [GO:0005178]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237] 0.58895 0.46035 LVRESSGGEVRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.62227 0 0 10.4691 0 0 0 0 0 0 0 0 0 O75083 WDR1_HUMAN WD repeat-containing protein 1 (Actin-interacting protein 1) (AIP1) (NORI-1) WDR1 Homo sapiens (Human) actin filament depolymerization [GO:0030042]; actin filament fragmentation [GO:0030043]; apical junction assembly [GO:0043297]; cortical cytoskeleton organization [GO:0030865]; establishment of planar polarity of follicular epithelium [GO:0042247]; locomotion [GO:0040011]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; neutrophil mediated immunity [GO:0002446]; neutrophil migration [GO:1990266]; platelet formation [GO:0030220]; positive regulation of actin filament depolymerization [GO:0030836]; regulation of actin filament depolymerization [GO:0030834]; regulation of cell shape [GO:0008360]; regulation of oligodendrocyte differentiation [GO:0048713]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; sarcomere organization [GO:0045214]; sensory perception of sound [GO:0007605] cell junction [GO:0030054]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cortical actin cytoskeleton [GO:0030864]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; podosome [GO:0002102] actin filament binding [GO:0051015] 0.0081522 2.1001 IAVVGEGR 0 0 0 0 0 0 0 0 0 0 0 0 10.0463 9.09376 0 0 0 0 0 9.97284 9.89382 0 10.0411 10.0091 11.2786 10.6408 10.5249 O75093 SLIT1_HUMAN Slit homolog 1 protein (Slit-1) (Multiple epidermal growth factor-like domains protein 4) (Multiple EGF-like domains protein 4) SLIT1 KIAA0813 MEGF4 SLIL1 Homo sapiens (Human) axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; dorsal/ventral axon guidance [GO:0033563]; forebrain morphogenesis [GO:0048853]; motor neuron axon guidance [GO:0008045]; negative chemotaxis [GO:0050919]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of synapse assembly [GO:0051964]; nuclear migration [GO:0007097]; retinal ganglion cell axon guidance [GO:0031290]; spinal cord development [GO:0021510]; tangential migration from the subventricular zone to the olfactory bulb [GO:0022028] extracellular space [GO:0005615] calcium ion binding [GO:0005509]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; Roundabout binding [GO:0048495] 0.96551 -2.2974 GDPVRDFHQVQR 0 0 0 0 0 0 0 0 14.3855 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75094 SLIT3_HUMAN Slit homolog 3 protein (Slit-3) (Multiple epidermal growth factor-like domains protein 5) (Multiple EGF-like domains protein 5) SLIT3 KIAA0814 MEGF5 SLIL2 UNQ691/PRO1336 Homo sapiens (Human) aortic valve morphogenesis [GO:0003180]; apoptotic process involved in luteolysis [GO:0061364]; atrioventricular valve morphogenesis [GO:0003181]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; cellular response to hormone stimulus [GO:0032870]; negative chemotaxis [GO:0050919]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; response to cortisol [GO:0051414]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412] extracellular space [GO:0005615]; mitochondrion [GO:0005739] calcium ion binding [GO:0005509]; heparin binding [GO:0008201]; Roundabout binding [GO:0048495] 0.96949 -5.4829 AGYKEPGIAR 0 0 0 0 0 8.5648 0 0 0 9.27805 9.2212 9.21888 0 0 0 0 0 0 0 9.75682 0 0 0 0 0 11.563 9.5815 O75096 LRP4_HUMAN Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) LRP4 KIAA0816 LRP10 MEGF7 Homo sapiens (Human) amyloid-beta clearance by cellular catabolic process [GO:0150094]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] cell surface [GO:0009986]; dendrite [GO:0030425]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; postsynaptic density [GO:0014069]; synaptic membrane [GO:0097060] apolipoprotein binding [GO:0034185]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; receptor tyrosine kinase binding [GO:0030971]; scaffold protein binding [GO:0097110] 0.96401 -2.3855 GDGKTCDPSPETYLLFSSRGSIR 0 0 0 0 0 0 0 0 14.0695 0 0 13.399 0 0 0 0 10.5734 0 0 0 0 0 0 0 0 0 0 O75110 ATP9A_HUMAN Probable phospholipid-transporting ATPase IIA (EC 7.6.2.1) (ATPase class II type 9A) ATP9A ATPIIA KIAA0611 Homo sapiens (Human) "endocytosis [GO:0006897]; negative regulation of exosomal secretion [GO:1903542]; phospholipid translocation [GO:0045332]; regulation of endocytic recycling [GO:2001135]; regulation of retrograde transport, endosome to Golgi [GO:1905279]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]" early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled intramembrane lipid transporter activity [GO:0140326]; magnesium ion binding [GO:0000287]; protease binding [GO:0002020] 0.30921 0.79802 RFSPPSYSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.1134 0 0 0 0 9.1816 0 0 0 0 0 0 O75112 LDB3_HUMAN LIM domain-binding protein 3 (Protein cypher) (Z-band alternatively spliced PDZ-motif protein) LDB3 KIAA0613 ZASP Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; heart development [GO:0007507]; muscle structure development [GO:0061061]; sarcomere organization [GO:0045214] adherens junction [GO:0005912]; cytoskeleton [GO:0005856]; filamentous actin [GO:0031941]; perinuclear region of cytoplasm [GO:0048471]; pseudopodium [GO:0031143]; stress fiber [GO:0001725]; Z disc [GO:0030018] actin binding [GO:0003779]; cytoskeletal protein binding [GO:0008092]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]; protein kinase C binding [GO:0005080] 0.84355 0.15296 TSPEGAR 0 0 0 0 9.44259 9.40797 10.4871 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75113 N4BP1_HUMAN NEDD4-binding protein 1 (N4BP1) (EC 3.1.-.-) N4BP1 KIAA0615 Homo sapiens (Human) cellular response to UV [GO:0034644]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; regulation of innate immune response [GO:0045088] cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleus [GO:0005634]; PML body [GO:0016605] mRNA binding [GO:0003729]; RNA nuclease activity [GO:0004540]; ubiquitin binding [GO:0043130] 0.96955 -4.7076 IPYKLELK 0 0 0 0 0 0 0 0 10.256 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75116 ROCK2_HUMAN "Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)" ROCK2 KIAA0619 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; aortic valve morphogenesis [GO:0003180]; blood vessel diameter maintenance [GO:0097746]; cellular response to acetylcholine [GO:1905145]; cellular response to testosterone stimulus [GO:0071394]; centrosome duplication [GO:0051298]; cortical actin cytoskeleton organization [GO:0030866]; embryonic morphogenesis [GO:0048598]; epithelial to mesenchymal transition [GO:0001837]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; mitotic cytokinesis [GO:0000281]; modulation by host of viral process [GO:0044788]; mRNA destabilization [GO:0061157]; negative regulation of angiogenesis [GO:0016525]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of gene expression [GO:0010629]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of protein localization to lysosome [GO:0150033]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of amyloid precursor protein catabolic process [GO:1902993]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell migration [GO:0030335]; positive regulation of centrosome duplication [GO:0010825]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of connective tissue replacement [GO:1905205]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of stress fiber assembly [GO:0051496]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of angiotensin-activated signaling pathway [GO:0110061]; regulation of cell adhesion [GO:0030155]; regulation of cell junction assembly [GO:1901888]; regulation of cell motility [GO:2000145]; regulation of cellular response to hypoxia [GO:1900037]; regulation of circadian rhythm [GO:0042752]; regulation of establishment of cell polarity [GO:2000114]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of focal adhesion assembly [GO:0051893]; regulation of keratinocyte differentiation [GO:0045616]; regulation of nervous system process [GO:0031644]; regulation of protein metabolic process [GO:0051246]; regulation of stress fiber assembly [GO:0051492]; response to angiotensin [GO:1990776]; response to ischemia [GO:0002931]; response to transforming growth factor beta [GO:0071559]; Rho protein signal transduction [GO:0007266]; rhythmic process [GO:0048511]; smooth muscle contraction [GO:0006939] centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; Rho-dependent protein serine/threonine kinase activity [GO:0072518]; RNA binding [GO:0003723]; small GTPase binding [GO:0031267]; structural molecule activity [GO:0005198]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321] 0.96938 -4.8262 ELEEEITLR 0 0 0 0 0 0 0 0 0 0 9.55718 10.3092 0 0 0 0 11.1463 10.8394 10.3568 0 8.78813 9.23795 0 9.67271 10.3768 0 0 O75122 CLAP2_HUMAN CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2) (Protein Orbit homolog 2) (hOrbit2) CLASP2 KIAA0627 Homo sapiens (Human) "cell division [GO:0051301]; establishment of mitotic spindle localization [GO:0040001]; establishment or maintenance of cell polarity [GO:0007163]; exit from mitosis [GO:0010458]; Golgi organization [GO:0007030]; microtubule anchoring [GO:0034453]; microtubule cytoskeleton organization [GO:0000226]; microtubule nucleation [GO:0007020]; microtubule organizing center organization [GO:0031023]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of exocytosis [GO:0045921]; positive regulation of extracellular matrix disassembly [GO:0090091]; protein localization to plasma membrane [GO:0072659]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of axon extension [GO:0030516]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of microtubule polymerization [GO:0031113]; regulation of microtubule polymerization or depolymerization [GO:0031110]; regulation of microtubule-based process [GO:0032886]; vesicle targeting [GO:0006903]" axonal growth cone [GO:0044295]; basal cortex [GO:0045180]; cell cortex [GO:0005938]; cell leading edge [GO:0031252]; cortical microtubule plus-end [GO:1903754]; cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; kinetochore [GO:0000776]; kinetochore microtubule [GO:0005828]; membrane [GO:0016020]; microtubule [GO:0005874]; microtubule organizing center [GO:0005815]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; spindle microtubule [GO:0005876]; trans-Golgi network [GO:0005802] actin filament binding [GO:0051015]; dystroglycan binding [GO:0002162]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein tyrosine kinase binding [GO:1990782] 0.96233 -2.0349 DTSPVRSFQPLASR 0 0 0 0 0 8.7003 0 0 7.84178 10.5083 0 10.5212 9.54156 0 13.7744 0 0 0 0 0 0 0 10.8393 9.69523 10.385 0 0 O75123 ZN623_HUMAN Zinc finger protein 623 ZNF623 KIAA0628 Homo sapiens (Human) nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.95268 -1.4683 DFIHYSGLIEHQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.62385 0 0 O75128 COBL_HUMAN Protein cordon-bleu COBL KIAA0633 Homo sapiens (Human) actin filament network formation [GO:0051639]; actin filament polymerization [GO:0030041]; collateral sprouting in absence of injury [GO:0048669]; digestive tract development [GO:0048565]; embryonic axis specification [GO:0000578]; floor plate development [GO:0033504]; liver development [GO:0001889]; neural tube closure [GO:0001843]; notochord development [GO:0030903]; positive regulation of dendrite development [GO:1900006]; positive regulation of ruffle assembly [GO:1900029]; somite specification [GO:0001757] actin filament [GO:0005884]; axon [GO:0030424]; axonal growth cone [GO:0044295]; cell cortex [GO:0005938]; dendrite [GO:0030425]; dendritic growth cone [GO:0044294]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; terminal web [GO:1990357] actin monomer binding [GO:0003785] 0.96418 -2.2579 DRVSVGQSCGFSGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.88583 9.82021 O75129 ASTN2_HUMAN Astrotactin-2 ASTN2 KIAA0634 Homo sapiens (Human) establishment of body hair planar orientation [GO:0048105]; negative regulation of protein localization to cell surface [GO:2000009]; neuron cell-cell adhesion [GO:0007158]; neuron migration [GO:0001764]; protein localization to cell surface [GO:0034394]; protein transport [GO:0015031] cell cortex [GO:0005938]; cell pole [GO:0060187]; clathrin-coated vesicle [GO:0030136]; early endosome [GO:0005769]; late endosome [GO:0005770]; membrane [GO:0016020]; perikaryon [GO:0043204] "calcium ion binding [GO:0005509]; inositol 1,3,4,5 tetrakisphosphate binding [GO:0043533]" 0.56449 0.4903 ETTELGSKKELK 10.7317 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75131 CPNE3_HUMAN Copine-3 (Copine III) CPNE3 CPN3 KIAA0636 Homo sapiens (Human) cellular response to calcium ion [GO:0071277]; cellular response to growth factor stimulus [GO:0071363]; ERBB2 signaling pathway [GO:0038128]; positive regulation of cell migration [GO:0030335] azurophil granule membrane [GO:0035577]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; metal ion binding [GO:0046872]; protein serine/threonine kinase activity [GO:0004674]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723] 0.69715 0.37893 LYGPTNFSPIINHVAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.63621 0 0 0 0 O75132 ZBED4_HUMAN Zinc finger BED domain-containing protein 4 ZBED4 KIAA0637 Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; photoreceptor inner segment [GO:0001917] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]; RNA binding [GO:0003723]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; transcription cis-regulatory region binding [GO:0000976]" 0.96821 -2.7744 AECRYCGCAISR 0 0 0 0 9.86482 9.98897 0 0 0 0 10.1675 0 0 0 0 0 0 0 0 0 0 0 9.5114 0 0 0 0 O75140 DEPD5_HUMAN GATOR complex protein DEPDC5 (DEP domain-containing protein 5) DEPDC5 KIAA0645 Homo sapiens (Human) cellular response to amino acid starvation [GO:0034198]; intracellular signal transduction [GO:0035556]; negative regulation of TOR signaling [GO:0032007]; negative regulation of TORC1 signaling [GO:1904262]; positive regulation of autophagy [GO:0010508] cytosol [GO:0005829]; GATOR1 complex [GO:1990130]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; perinuclear region of cytoplasm [GO:0048471] GTPase activator activity [GO:0005096]; protein-containing complex binding [GO:0044877] 0.96987 -4.1616 GDMWRLKK 0 0 0 0 0 0 10.7309 0 0 0 0 0 0 0 0 0 0 0 9.04821 0 0 0 0 9.88379 8.96284 0 0 O75143 ATG13_HUMAN Autophagy-related protein 13 ATG13 KIAA0652 Homo sapiens (Human) autophagosome assembly [GO:0000045]; mitophagy [GO:0000423]; negative regulation of cell population proliferation [GO:0008285]; piecemeal microautophagy of the nucleus [GO:0034727]; positive regulation of autophagy [GO:0010508]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein autophosphorylation [GO:0046777]; protein localization to phagophore assembly site [GO:0034497]; protein phosphorylation [GO:0006468]; regulation of protein lipidation [GO:1903059]; response to mitochondrial depolarisation [GO:0098780] Atg1/ULK1 kinase complex [GO:1990316]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; phagophore assembly site [GO:0000407] protein kinase binding [GO:0019901] 0.82187 0.21796 DIPEVTHEAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3058 O75145 LIPA3_HUMAN Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3) PPFIA3 KIAA0654 Homo sapiens (Human) neurotransmitter secretion [GO:0007269]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synapse organization [GO:0050808]; synaptic vesicle docking [GO:0016081] acrosomal vesicle [GO:0001669]; cytosol [GO:0005829]; epididymosome [GO:0098875]; glutamatergic synapse [GO:0098978]; presynaptic active zone [GO:0048786]; presynaptic active zone cytoplasmic component [GO:0098831] 0.93975 -1.3252 ELGHEKDSLQR 0 0 0 0 0 0 0 0 0 11.8585 11.5297 11.8936 0 8.80993 0 0 0 10.409 0 9.40035 0 0 0 0 9.77028 0 0 O75146 HIP1R_HUMAN Huntingtin-interacting protein 1-related protein (HIP1-related protein) (Huntingtin-interacting protein 12) (HIP-12) HIP1R HIP12 KIAA0655 Homo sapiens (Human) actin filament organization [GO:0007015]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; clathrin coat assembly [GO:0048268]; digestive system development [GO:0055123]; endocytosis [GO:0006897]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of apoptotic process [GO:0043066]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of apoptotic process [GO:0043065]; positive regulation of clathrin coat assembly [GO:1905445]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901030]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of protein binding [GO:0032092]; postsynapse organization [GO:0099173]; protein stabilization [GO:0050821]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of clathrin-dependent endocytosis [GO:2000369]; regulation of endocytosis [GO:0030100]; regulation of gastric acid secretion [GO:0060453] apical plasma membrane [GO:0016324]; cell cortex [GO:0005938]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; clathrin-coated vesicle membrane [GO:0030665]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; ruffle membrane [GO:0032587]; synaptic membrane [GO:0097060] "actin filament binding [GO:0051015]; clathrin adaptor activity [GO:0035615]; clathrin binding [GO:0030276]; clathrin light chain binding [GO:0032051]; identical protein binding [GO:0042802]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SH3 domain binding [GO:0017124]" 0.96942 -5.7021 DRFHEQFHSLR 0 8.78149 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6358 0 0 0 0 0 O75147 OBSL1_HUMAN Obscurin-like protein 1 OBSL1 KIAA0657 Homo sapiens (Human) cardiac myofibril assembly [GO:0055003]; cytoskeleton organization [GO:0007010]; Golgi organization [GO:0007030]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of dendrite morphogenesis [GO:0050775]; protein localization to Golgi apparatus [GO:0034067]; regulation of mitotic nuclear division [GO:0007088] 3M complex [GO:1990393]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intercalated disc [GO:0014704]; M band [GO:0031430]; perinuclear region of cytoplasm [GO:0048471]; Z disc [GO:0030018] cytoskeletal anchor activity [GO:0008093] 0.95924 -1.7117 CAARLIVR 10.6186 10.5869 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5231 0 0 0 0 O75150 BRE1B_HUMAN E3 ubiquitin-protein ligase BRE1B (BRE1-B) (EC 2.3.2.27) (95 kDa retinoblastoma-associated protein) (RBP95) (RING finger protein 40) (RING-type E3 ubiquitin transferase BRE1B) RNF40 BRE1B KIAA0661 Homo sapiens (Human) chromatin organization [GO:0006325]; histone H2B conserved C-terminal lysine ubiquitination [GO:0071894]; histone monoubiquitination [GO:0010390]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein polyubiquitination [GO:1902916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to peptide hormone [GO:0043434]; ubiquitin-dependent protein catabolic process [GO:0006511] HULC complex [GO:0033503]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151] metal ion binding [GO:0046872]; mRNA 3'-UTR binding [GO:0003730]; protein homodimerization activity [GO:0042803]; syntaxin-1 binding [GO:0017075]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625] 0.96944 -5.5306 ALQGSLGGVEK 0 0 12.3862 0 0 0 0 0 0 0 0 0 0 0 0 0 9.71783 0 0 0 0 0 0 0 0 10.9348 0 O75151 PHF2_HUMAN Lysine-specific demethylase PHF2 (EC 1.14.11.-) (GRC5) (PHD finger protein 2) PHF2 CENP-35 KIAA0662 Homo sapiens (Human) liver development [GO:0001889]; negative regulation of rDNA heterochromatin formation [GO:0061188]; protein demethylation [GO:0006482]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription initiation-coupled chromatin remodeling [GO:0045815] kinetochore [GO:0000776]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] histone H3K9 demethylase activity [GO:0032454]; histone H4K20 demethylase activity [GO:0035575]; iron ion binding [GO:0005506]; methylated histone binding [GO:0035064]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; zinc ion binding [GO:0008270] 0.82976 0.20445 EALTKMEPPK 0 0 0 0 0 0 10.2155 0 0 9.89615 0 0 0 0 0 0 0 0 0 9.63519 0 0 0 0 0 0 9.87129 O75153 CLU_HUMAN Clustered mitochondria protein homolog CLUH KIAA0664 Homo sapiens (Human) intracellular distribution of mitochondria [GO:0048312]; mitochondrion organization [GO:0007005] cytoplasm [GO:0005737] mRNA binding [GO:0003729] 0.97002 -5.2352 ASDAFHFFQSGQAK 9.60223 0 0 0 0 0 0 0 0 11.0719 0 0 0 0 0 0 0 9.88345 0 0 0 0 8.08518 0 10.3185 0 9.70801 O75154 RFIP3_HUMAN Rab11 family-interacting protein 3 (FIP3-Rab11) (Rab11-FIP3) (Arfophilin-1) (EF hands-containing Rab-interacting protein) (Eferin) (MU-MB-17.148) RAB11FIP3 ARFO1 KIAA0665 Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; endocytic recycling [GO:0032456]; negative regulation of adiponectin secretion [GO:0070164]; protein localization to cilium [GO:0061512]; regulation of cytokinesis [GO:0032465]; vesicle-mediated transport [GO:0016192] centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cleavage furrow [GO:0032154]; cytosol [GO:0005829]; endocytic vesicle [GO:0030139]; endosome [GO:0005768]; intercellular bridge [GO:0045171]; intracellular membrane-bounded organelle [GO:0043231]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; postsynaptic recycling endosome membrane [GO:0098944]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038] calcium ion binding [GO:0005509]; dynein light intermediate chain binding [GO:0051959]; protein homodimerization activity [GO:0042803]; small GTPase binding [GO:0031267] 0.92285 -1.0598 ELLCKMEREK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3098 10.2838 10.1315 0 0 0 O75155 CAND2_HUMAN Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (Epididymis tissue protein Li 169) (TBP-interacting protein of 120 kDa B) (TBP-interacting protein 120B) (p120 CAND2) CAND2 KIAA0667 TIP120B Homo sapiens (Human) positive regulation of DNA-templated transcription [GO:0045893]; protein ubiquitination [GO:0016567]; SCF complex assembly [GO:0010265] cytosol [GO:0005829]; nucleus [GO:0005634] TBP-class protein binding [GO:0017025] 0.95431 -1.5311 ALWPLHRPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.418 0 0 0 9.9402 0 0 0 0 0 0 O75159 SOCS5_HUMAN Suppressor of cytokine signaling 5 (SOCS-5) (Cytokine-inducible SH2 protein 6) (CIS-6) (Cytokine-inducible SH2-containing protein 5) SOCS5 CIS6 CISH5 CISH6 KIAA0671 Homo sapiens (Human) cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cytokine-mediated signaling pathway [GO:0019221]; epidermal growth factor receptor signaling pathway [GO:0007173]; intracellular signal transduction [GO:0035556]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of signal transduction [GO:0009968]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of T-helper 1 cell differentiation [GO:0045627]; protein ubiquitination [GO:0016567]; receptor signaling pathway via JAK-STAT [GO:0007259]; vascular endothelial cell response to fluid shear stress [GO:0097699] cytosol [GO:0005829]; phosphatidylinositol 3-kinase complex [GO:0005942] 1-phosphatidylinositol-3-kinase regulator activity [GO:0046935]; epidermal growth factor receptor binding [GO:0005154]; receptor tyrosine kinase binding [GO:0030971] 0.95439 -1.5051 VGKMWNNFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.84375 0 0 0 0 0 0 O75161 NPHP4_HUMAN Nephrocystin-4 (Nephroretinin) NPHP4 KIAA0673 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell-cell adhesion [GO:0098609]; flagellated sperm motility [GO:0030317]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; photoreceptor cell maintenance [GO:0045494]; photoreceptor cell outer segment organization [GO:0035845]; positive regulation of bicellular tight junction assembly [GO:1903348]; protein localization to ciliary transition zone [GO:1904491]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; visual behavior [GO:0007632] bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary base [GO:0097546]; ciliary transition zone [GO:0035869]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; non-motile cilium [GO:0097730]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; photoreceptor distal connecting cilium [GO:0120206]; ribbon synapse [GO:0097470] structural molecule activity [GO:0005198] 0.96675 -2.3528 LQEAGGDLGRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1562 0 0 0 0 0 0 0 0 0 O75164 KDM4A_HUMAN Lysine-specific demethylase 4A (EC 1.14.11.66) (EC 1.14.11.69) (JmjC domain-containing histone demethylation protein 3A) (Jumonji domain-containing protein 2A) ([histone H3]-trimethyl-L-lysine(36) demethylase 4A) ([histone H3]-trimethyl-L-lysine(9) demethylase 4A) KDM4A JHDM3A JMJD2 JMJD2A KIAA0677 Homo sapiens (Human) cardiac muscle hypertrophy in response to stress [GO:0014898]; chromatin remodeling [GO:0006338]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of autophagy [GO:0010507]; negative regulation of cell death [GO:0060548]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; response to nutrient levels [GO:0031667] cytosol [GO:0005829]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721] histone demethylase activity [GO:0032452]; histone H3K36 demethylase activity [GO:0051864]; histone H3K36me2/H3K36me3 demethylase activity [GO:0140681]; histone H3K9 demethylase activity [GO:0032454]; histone H3K9me2/H3K9me3 demethylase activity [GO:0140684]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270] 0.94782 -1.3539 ESELPPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.57901 0 0 0 0 0 0 9.52925 0 0 0 O75165 DJC13_HUMAN DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8) DNAJC13 KIAA0678 RME8 Homo sapiens (Human) endosome organization [GO:0007032]; osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of early endosome to recycling endosome transport [GO:1902954] azurophil granule membrane [GO:0035577]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667] 0.95484 -1.537 DRMGIAQK 0 0 0 0 10.9996 0 0 0 0 0 0 0 0 0 10.7951 0 0 0 0 0 0 0 0 8.9364 0 9.89922 0 O75167 PHAR2_HUMAN Phosphatase and actin regulator 2 PHACTR2 C6orf56 KIAA0680 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036] plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092] actin binding [GO:0003779]; protein phosphatase inhibitor activity [GO:0004864] 0.89913 -0.63992 DNAVDGLDK 0 0 0 0 11.3224 0 0 0 0 0 12.0091 0 0 0 0 0 0 0 9.49783 0 0 0 0 0 9.44663 0 0 O75170 PP6R2_HUMAN Serine/threonine-protein phosphatase 6 regulatory subunit 2 (SAPS domain family member 2) PPP6R2 KIAA0685 PP6R2 SAPS2 Homo sapiens (Human) regulation of phosphoprotein phosphatase activity [GO:0043666] cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634] protein phosphatase binding [GO:0019903]; protein phosphatase regulator activity [GO:0019888] 0.20611 0.91388 HIGTSALMDLLLR 14.4673 14.5791 14.0955 13.3424 13.1371 12.9436 12.0075 12.4839 0 0 0 0 0 0 0 0 10.6202 0 0 0 0 0 0 0 8.84966 9.56539 9.64405 O75175 CNOT3_HUMAN CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3) (Leukocyte receptor cluster member 2) CNOT3 KIAA0691 LENG2 NOT3 Homo sapiens (Human) nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of DNA-templated transcription [GO:0006355]; regulation of stem cell population maintenance [GO:2000036]; RNA-mediated gene silencing [GO:0031047]; trophectodermal cell differentiation [GO:0001829] CCR4-NOT complex [GO:0030014]; CCR4-NOT core complex [GO:0030015]; cytosol [GO:0005829]; nucleus [GO:0005634]; P-body [GO:0000932] 0.91418 -0.81725 YLEDRDLQ 0 0 0 0 0 10.3796 0 0 0 0 0 9.4719 10.0167 0 9.38509 0 0 0 9.69491 10.2751 11.1604 11.3106 11.3307 0 0 0 0 O75179 ANR17_HUMAN Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16) ANKRD17 GTAR KIAA0697 Homo sapiens (Human) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] chromatin [GO:0000785]; cytoplasm [GO:0005737]; male germ cell nucleus [GO:0001673]; membrane [GO:0016020]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; RNA binding [GO:0003723] 0.95274 -1.4736 FCELLIGR 0 0 0 0 0 0 0 0 0 0 0 0 0 12.0056 10.9174 0 0 0 0 0 0 0 0 0 9.88495 0 0 O75182 SIN3B_HUMAN Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b) SIN3B KIAA0700 Homo sapiens (Human) negative regulation of cell migration [GO:0030336]; negative regulation of transcription by RNA polymerase II [GO:0000122] autosome [GO:0030849]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Sin3 complex [GO:0016580]; X chromosome [GO:0000805]; XY body [GO:0001741]; Y chromosome [GO:0000806] chromatin binding [GO:0003682]; transcription corepressor activity [GO:0003714] 0.96025 -1.7979 EIDYASCK 11.9233 0 0 0 0 0 0 11.7166 0 0 0 0 0 0 9.90491 0 0 0 0 9.53493 0 0 0 0 0 0 0 O75192 PX11A_HUMAN Peroxisomal membrane protein 11A (HsPEX11p) (28 kDa peroxisomal integral membrane protein) (PMP28) (Peroxin-11A) (Peroxisomal biogenesis factor 11A) (Protein PEX11 homolog alpha) (PEX11-alpha) PEX11A PEX11 Homo sapiens (Human) brown fat cell differentiation [GO:0050873]; peroxisome fission [GO:0016559]; peroxisome membrane biogenesis [GO:0016557]; peroxisome organization [GO:0007031]; regulation of peroxisome size [GO:0044375]; signal transduction [GO:0007165] peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991] protein homodimerization activity [GO:0042803] 0.89924 -0.68527 LESSVSTGRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.89404 0 0 0 O75197 LRP5_HUMAN Low-density lipoprotein receptor-related protein 5 (LRP-5) (Low-density lipoprotein receptor-related protein 7) (LRP-7) LRP5 LR3 LRP7 Homo sapiens (Human) adipose tissue development [GO:0060612]; amino acid transport [GO:0006865]; anatomical structure regression [GO:0060033]; anterior/posterior pattern specification [GO:0009952]; apoptotic process involved in blood vessel morphogenesis [GO:1902262]; bone marrow development [GO:0048539]; bone morphogenesis [GO:0060349]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cell-cell signaling involved in mammary gland development [GO:0060764]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; establishment of blood-brain barrier [GO:0060856]; establishment of blood-retinal barrier [GO:1990963]; extracellular matrix-cell signaling [GO:0035426]; gastrulation with mouth forming second [GO:0001702]; gene expression [GO:0010467]; glucose catabolic process [GO:0006007]; mesodermal cell migration [GO:0008078]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; Norrin signaling pathway [GO:0110135]; osteoblast development [GO:0002076]; osteoblast proliferation [GO:0033687]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of blood pressure [GO:0008217]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; retina morphogenesis in camera-type eye [GO:0060042]; retinal blood vessel morphogenesis [GO:0061304]; somatic stem cell population maintenance [GO:0035019] endoplasmic reticulum [GO:0005783]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; Wnt signalosome [GO:1990909]; Wnt-Frizzled-LRP5/6 complex [GO:1990851] coreceptor activity [GO:0015026]; coreceptor activity involved in canonical Wnt signaling pathway [GO:1904928]; coreceptor activity involved in Wnt signaling pathway [GO:0071936]; Wnt receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147] 0.88396 -0.13851 ILVSEDLDEPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9473 0 0 O75208 COQ9_HUMAN "Ubiquinone biosynthesis protein COQ9, mitochondrial" COQ9 C16orf49 HSPC326 PSEC0129 Homo sapiens (Human) "mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; ubiquinone biosynthetic process [GO:0006744]" mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ubiquinone biosynthesis complex [GO:0110142] lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803] 0.9228 -1.1588 AFHASAVGLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.45541 0 0 0 10.7924 0 0 0 0 O75223 GGCT_HUMAN Gamma-glutamylcyclotransferase (EC 4.3.2.9) (Cytochrome c-releasing factor 21) GGCT C7orf24 CRF21 Homo sapiens (Human) release of cytochrome c from mitochondria [GO:0001836] cytosol [GO:0005829]; extracellular exosome [GO:0070062] gamma-glutamylcyclotransferase activity [GO:0003839]; protein homodimerization activity [GO:0042803] 0.89028 -0.48982 ENGLPLEYQEKLK 0 0 0 0 0 11.5868 0 0 0 0 0 13.9337 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75293 GA45B_HUMAN Growth arrest and DNA damage-inducible protein GADD45 beta (Myeloid differentiation primary response protein MyD118) (Negative growth regulatory protein MyD118) GADD45B MYD118 Homo sapiens (Human) apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of apoptotic process [GO:0043065]; positive regulation of JNK cascade [GO:0046330]; positive regulation of p38MAPK cascade [GO:1900745]; regulation of cell cycle [GO:0051726] cytoplasm [GO:0005737]; nucleus [GO:0005634] 0.84788 0.12913 DLHCLLVTNPHTDAWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.1005 0 0 O75306 NDUS2_HUMAN "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (EC 7.1.1.2) (Complex I-49kD) (CI-49kD) (NADH-ubiquinone oxidoreductase 49 kDa subunit)" NDUFS2 Homo sapiens (Human) "aerobic respiration [GO:0009060]; cellular response to oxygen levels [GO:0071453]; gliogenesis [GO:0042063]; mitochondrial ATP synthesis coupled electron transport [GO:0042775]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; neural precursor cell proliferation [GO:0061351]; neurogenesis [GO:0022008]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]; response to oxidative stress [GO:0006979]" mitochondrial matrix [GO:0005759]; mitochondrial respiratory chain complex I [GO:0005747]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] "4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; NADH dehydrogenase (ubiquinone) activity [GO:0008137]; oxygen sensor activity [GO:0019826]; quinone binding [GO:0048038]; ubiquitin protein ligase binding [GO:0031625]" 0.009901 1.8309 LDELEELLTNNR 11.4031 11.2039 11.2912 10.4001 10.7354 10.6243 11.0635 0 11.4681 11.8863 0 11.3798 0 0 10.7735 0 10.9044 0 0 0 0 0 0 0 11.0318 0 0 O75309 CAD16_HUMAN Cadherin-16 (Kidney-specific cadherin) (Ksp-cadherin) CDH16 UNQ695/PRO1340 Homo sapiens (Human) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] basolateral plasma membrane [GO:0016323]; extracellular exosome [GO:0070062] calcium ion binding [GO:0005509] 0.91417 -0.77836 FSLVNDSEGWLCIEK 0 0 0 0 0 0 9.53448 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75311 GLRA3_HUMAN Glycine receptor subunit alpha-3 GLRA3 Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; nervous system process [GO:0050877]; protein homooligomerization [GO:0051260]; regulation of membrane potential [GO:0042391]; response to amino acid [GO:0043200]; signal transduction [GO:0007165] dendrite [GO:0030425]; glycine-gated chloride channel complex [GO:0016935]; intracellular membrane-bounded organelle [GO:0043231]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202] extracellularly glycine-gated chloride channel activity [GO:0016934]; glycine binding [GO:0016594]; glycine-gated chloride ion channel activity [GO:0022852]; metal ion binding [GO:0046872]; neurotransmitter receptor activity [GO:0030594]; transmembrane signaling receptor activity [GO:0004888] 0.96848 -2.7765 DLRYCTK 0 0 0 0 0 0 0 0 0 0 0 0 10.6319 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75319 DUS11_HUMAN RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Dual specificity protein phosphatase 11) (Phosphatase that interacts with RNA/RNP complex 1) DUSP11 PIR1 Homo sapiens (Human) protein dephosphorylation [GO:0006470]; RNA processing [GO:0006396] fibrillar center [GO:0001650]; intercellular bridge [GO:0045171]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] phosphatase activity [GO:0016791]; polynucleotide 5'-phosphatase activity [GO:0004651]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; RNA binding [GO:0003723] 0.51714 0.59882 LLGTHMSQWHHPRSGWGRR 0 12.091 0 0 11.8091 0 0 9.54988 0 0 0 0 0 13.3163 0 0 0 0 0 0 0 0 0 0 0 0 0 O75323 NIPS2_HUMAN Protein NipSnap homolog 2 (NipSnap2) (Glioblastoma-amplified sequence) NIPSNAP2 GBAS Homo sapiens (Human) mitochondrion organization [GO:0007005]; oxidative phosphorylation [GO:0006119]; positive regulation of high voltage-gated calcium channel activity [GO:1901843] mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739] 0.96552 -2.7235 DLQTREDIR 0 0 0 0 0 0 9.60261 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75325 LRRN2_HUMAN Leucine-rich repeat neuronal protein 2 (Glioma amplified on chromosome 1 protein) (Leucine-rich repeat neuronal protein 5) LRRN2 GAC1 LRRN5 UNQ256/PRO293 Homo sapiens (Human) cell adhesion [GO:0007155]; signal transduction [GO:0007165] extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; membrane [GO:0016020] signaling receptor activity [GO:0038023] 0.91517 -0.79147 LHLNSNLLRAIDSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2651 0 0 0 O75326 SEM7A_HUMAN Semaphorin-7A (CDw108) (JMH blood group antigen) (John-Milton-Hargen human blood group Ag) (Semaphorin-K1) (Sema K1) (Semaphorin-L) (Sema L) (CD antigen CD108) SEMA7A CD108 SEMAL Homo sapiens (Human) axon extension [GO:0048675]; immune response [GO:0006955]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; negative chemotaxis [GO:0050919]; negative regulation of axon extension involved in axon guidance [GO:0048843]; neural crest cell migration [GO:0001755]; olfactory lobe development [GO:0021988]; osteoblast differentiation [GO:0001649]; positive regulation of axon extension [GO:0045773]; positive regulation of cell migration [GO:0030335]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of protein phosphorylation [GO:0001934]; protein phosphorylation [GO:0006468]; regulation of inflammatory response [GO:0050727]; semaphorin-plexin signaling pathway [GO:0071526] external side of plasma membrane [GO:0009897]; membrane [GO:0016020]; plasma membrane [GO:0005886] chemorepellent activity [GO:0045499]; integrin binding [GO:0005178]; semaphorin receptor binding [GO:0030215] 0.82258 0.21713 CISIYSSER 0 0 0 0 0 0 0 0 0 0 0 10.1684 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75330 HMMR_HUMAN Hyaluronan mediated motility receptor (Intracellular hyaluronic acid-binding protein) (Receptor for hyaluronan-mediated motility) (CD antigen CD168) HMMR IHABP RHAMM Homo sapiens (Human) hyaluronan catabolic process [GO:0030214]; receptor-mediated endocytosis [GO:0006898] cell surface [GO:0009986]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; plasma membrane [GO:0005886]; spindle [GO:0005819] cargo receptor activity [GO:0038024]; hyaluronic acid binding [GO:0005540] 0.96316 -2.1527 AFHHESK 9.94028 0 0 0 0 0 0 0 0 0 9.37321 0 0 9.7854 0 0 0 0 0 9.90743 0 0 9.50006 0 0 0 0 O75334 LIPA2_HUMAN Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2) PPFIA2 Homo sapiens (Human) cell-matrix adhesion [GO:0007160]; dense core granule cytoskeletal transport [GO:0099519]; regulation of dendritic spine development [GO:0060998]; regulation of dendritic spine morphogenesis [GO:0061001]; synapse organization [GO:0050808] axon [GO:0030424]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; presynaptic active zone [GO:0048786] 0.96254 -2.0838 AEERHGNIEER 8.56674 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.25781 0 0 0 0 O75335 LIPA4_HUMAN Liprin-alpha-4 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-4) (PTPRF-interacting protein alpha-4) PPFIA4 KIAA0897 Homo sapiens (Human) synapse organization [GO:0050808] cell surface [GO:0009986]; cytosol [GO:0005829]; presynaptic active zone [GO:0048786]; synapse [GO:0045202] 0.96893 -3.5965 DGAAEEEGTVELGPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1933 9.74436 0 0 0 0 0 0 12.4108 O75339 CILP1_HUMAN Cartilage intermediate layer protein 1 (CILP-1) (Cartilage intermediate-layer protein) [Cleaved into: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2] CILP UNQ602/PRO1188 Homo sapiens (Human) negative regulation of gene expression [GO:0010629]; negative regulation of insulin-like growth factor receptor signaling pathway [GO:0043569]; negative regulation of SMAD protein signal transduction [GO:0060392]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512] collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615] 0.96769 -3.7382 CFVKVRAYR 9.23613 0 0 0 0 0 9.31829 0 0 0 0 0 0 0 0 11.129 12.6476 10.9575 0 10.2629 0 0 0 0 0 0 10.5967 O75340 PDCD6_HUMAN Programmed cell death protein 6 (Apoptosis-linked gene 2 protein homolog) (ALG-2) PDCD6 ALG2 Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic signaling pathway [GO:0097190]; cellular response to heat [GO:0034605]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein monoubiquitination [GO:1902527]; response to calcium ion [GO:0051592]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324] COPII vesicle coat [GO:0030127]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein-macromolecule adaptor activity [GO:0030674]; protein-membrane adaptor activity [GO:0043495]; ubiquitin ligase-substrate adaptor activity [GO:1990756] 0.92166 -1.0945 SIISMFDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7.7896 0 0 0 O75342 LX12B_HUMAN "Arachidonate 12-lipoxygenase, 12R-type (12R-LOX) (12R-lipoxygenase) (EC 1.13.11.-) (Epidermis-type lipoxygenase 12)" ALOX12B Homo sapiens (Human) arachidonic acid metabolic process [GO:0019369]; ceramide biosynthetic process [GO:0046513]; establishment of skin barrier [GO:0061436]; hepoxilin biosynthetic process [GO:0051122]; linoleic acid metabolic process [GO:0043651]; lipid oxidation [GO:0034440]; lipoxygenase pathway [GO:0019372]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mucus secretion [GO:0070257]; protein lipidation [GO:0006497]; sphingolipid metabolic process [GO:0006665] cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; perinuclear region of cytoplasm [GO:0048471] "arachidonate 12(R)-lipoxygenase activity [GO:0106237]; arachidonate 12(S)-lipoxygenase activity [GO:0004052]; arachidonate 8(R)-lipoxygenase activity [GO:0047677]; iron ion binding [GO:0005506]; isomerase activity [GO:0016853]; linoleate 9S-lipoxygenase activity [GO:1990136]; lyase activity [GO:0016829]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]" 0.56465 0.50374 AVLLNEGGLSAK 0 0 0 0 0 0 0 0 9.02777 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75343 GCYB2_HUMAN Guanylate cyclase soluble subunit beta-2 (GCS-beta-2) (EC 4.6.1.2) GUCY1B2 Homo sapiens (Human) cGMP-mediated signaling [GO:0019934]; response to oxygen levels [GO:0070482] "cytosol [GO:0005829]; guanylate cyclase complex, soluble [GO:0008074]" GTP binding [GO:0005525]; guanylate cyclase activity [GO:0004383]; heme binding [GO:0020037]; metal ion binding [GO:0046872] 0.8298 0.20618 SIVMFGK 10.9977 10.9016 0 0 0 0 0 0 0 0 0 10.9627 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75346 ZN253_HUMAN Zinc finger protein 253 (Bone marrow zinc finger 1) (BMZF-1) (Zinc finger protein 411) ZNF253 BMZF1 ZNF411 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.87054 0.049793 AFNHSTTLFSHEK 0 0 0 0 0 0 0 0 0 0 0 8.89051 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75347 TBCA_HUMAN Tubulin-specific chaperone A (TCP1-chaperonin cofactor A) (Tubulin-folding cofactor A) (CFA) TBCA Homo sapiens (Human) post-chaperonin tubulin folding pathway [GO:0007023]; protein folding [GO:0006457]; tubulin complex assembly [GO:0007021] cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; nucleolus [GO:0005730] beta-tubulin binding [GO:0048487]; protein-folding chaperone binding [GO:0051087]; RNA binding [GO:0003723]; tubulin binding [GO:0015631] 0.55937 0.54012 LEAAYLDLQR 10.8972 8.41287 0 0 0 0 0 0 0 11.9617 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75351 VPS4B_HUMAN Vacuolar protein sorting-associated protein 4B (EC 3.6.4.6) (Cell migration-inducing gene 1 protein) (Suppressor of K(+) transport growth defect 1) (Protein SKD1) VPS4B SKD1 VPS42 MIG1 Homo sapiens (Human) angiogenesis [GO:0001525]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; canonical Wnt signaling pathway [GO:0060070]; cholesterol transport [GO:0030301]; endosomal transport [GO:0016197]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ESCRT III complex disassembly [GO:1904903]; establishment of blood-brain barrier [GO:0060856]; late endosomal microautophagy [GO:0061738]; late endosome to lysosome transport via multivesicular body sorting pathway [GO:0061764]; macroautophagy [GO:0016236]; membrane fission [GO:0090148]; midbody abscission [GO:0061952]; mitotic metaphase plate congression [GO:0007080]; multivesicular body assembly [GO:0036258]; multivesicular body sorting pathway [GO:0071985]; negative regulation of cell death [GO:0060548]; negative regulation of exosomal secretion [GO:1903542]; nuclear membrane reassembly [GO:0031468]; nucleus organization [GO:0006997]; plasma membrane repair [GO:0001778]; positive regulation of centriole elongation [GO:1903724]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; potassium ion transport [GO:0006813]; protein depolymerization [GO:0051261]; protein transport [GO:0015031]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic spindle assembly [GO:1901673]; response to lipid [GO:0033993]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway [GO:0090611]; vacuole organization [GO:0007033]; viral budding from plasma membrane [GO:0046761]; viral budding via host ESCRT complex [GO:0039702] ATPase complex [GO:1904949]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; late endosome membrane [GO:0031902]; midbody [GO:0030496]; nuclear pore [GO:0005643]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; spindle pole [GO:0000922] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877] 0.96269 -2.1732 AIDLASKAAQEDK 0 0 0 0 0 0 0 10.8637 0 0 0 0 0 0 0 0 0 0 11 0 0 0 0 0 0 9.96259 0 O75354 ENTP6_HUMAN Ectonucleoside triphosphate diphosphohydrolase 6 (NTPDase 6) (EC 3.6.1.6) (CD39 antigen-like 2) ENTPD6 CD39L2 IL6ST2 Homo sapiens (Human) nucleoside diphosphate catabolic process [GO:0009134]; response to calcium ion [GO:0051592]; response to magnesium ion [GO:0032026] cell surface [GO:0009986]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; plasma membrane [GO:0005886] "CDP phosphatase activity [GO:0036384]; GDP phosphatase activity [GO:0004382]; guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity [GO:0008894]; IDP phosphatase activity [GO:1990003]; nucleoside diphosphate phosphatase activity [GO:0017110]; ribonucleoside triphosphate phosphatase activity [GO:0017111]; UDP phosphatase activity [GO:0045134]" 0.95914 -1.8353 AAASLHELCAAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3574 0 O75356 ENTP5_HUMAN Nucleoside diphosphate phosphatase ENTPD5 (EC 3.6.1.6) (CD39 antigen-like 4) (ER-UDPase) (Ectonucleoside triphosphate diphosphohydrolase 5) (NTPDase 5) (Guanosine-diphosphatase ENTPD5) (GDPase ENTPD5) (Inosine diphosphate phosphatase ENTPD5) (Nucleoside diphosphatase) (Uridine-diphosphatase ENTPD5) (UDPase ENTPD5) ENTPD5 CD39L4 PCPH Homo sapiens (Human) 'de novo' post-translational protein folding [GO:0051084]; nucleoside diphosphate catabolic process [GO:0009134]; protein N-linked glycosylation [GO:0006487]; UDP catabolic process [GO:0006256]; UDP-glucose metabolic process [GO:0006011] endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020] ADP phosphatase activity [GO:0043262]; CDP phosphatase activity [GO:0036384]; GDP phosphatase activity [GO:0004382]; IDP phosphatase activity [GO:1990003]; UDP phosphatase activity [GO:0045134] 0.87119 0.043111 GYLTSFEMFNSTYK 0 0 0 0 0 0 0 11.4699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75362 ZN217_HUMAN Zinc finger protein 217 ZNF217 ZABC1 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] histone deacetylase complex [GO:0000118]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; transcription cis-regulatory region binding [GO:0000976]" 0.97024 -3.2568 APLTSGIDSSTLAPSNLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.64701 0 0 0 0 0 9.87357 0 0 9.09853 O75363 BCAS1_HUMAN Breast carcinoma-amplified sequence 1 (Amplified and overexpressed in breast cancer) (Novel amplified in breast cancer 1) BCAS1 AIBC1 NABC1 Homo sapiens (Human) myelination [GO:0042552] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062] 0.95342 -1.4961 AETKKDPEDTGAEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.169 O75367 H2AY_HUMAN Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205) MACROH2A1 H2AFY Homo sapiens (Human) "DNA repair [GO:0006281]; dosage compensation [GO:0007549]; epigenetic regulation of gene expression [GO:0040029]; establishment of protein localization to chromatin [GO:0071169]; negative regulation of cell cycle G2/M phase transition [GO:1902750]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of protein localization to chromosome, telomeric region [GO:1904815]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of response to oxidative stress [GO:1902883]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901837]; nucleosome assembly [GO:0006334]; positive regulation of endodermal cell differentiation [GO:1903226]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of response to oxidative stress [GO:1902884]; regulation of lipid metabolic process [GO:0019216]; regulation of NAD metabolic process [GO:1902688]; regulation of oxidative phosphorylation [GO:0002082]; regulation of response to oxidative stress [GO:1902882]; transcription initiation-coupled chromatin remodeling [GO:0045815]" "Barr body [GO:0001740]; chromatin [GO:0000785]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; extracellular exosome [GO:0070062]; nuclear chromosome [GO:0000228]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; sex chromatin [GO:0001739]; site of DNA damage [GO:0090734]" ADP-D-ribose binding [GO:0072570]; ADP-D-ribose modification-dependent protein binding [GO:0160002]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; double-stranded methylated DNA binding [GO:0010385]; enzyme binding [GO:0019899]; nucleosomal DNA binding [GO:0031492]; poly-ADP-D-ribose modification-dependent protein binding [GO:0160004]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein serine/threonine kinase inhibitor activity [GO:0030291]; rDNA binding [GO:0000182]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; structural constituent of chromatin [GO:0030527]; transcription cis-regulatory region binding [GO:0000976] 0.92226 -1.1038 LEAIITPPPAK 0 0 0 0 0 0 0 0 0 0 0 0 0 12.2764 0 0 11.0927 0 0 0 0 0 0 0 0 0 0 O75369 FLNB_HUMAN Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP) FLNB FLN1L FLN3 TABP TAP Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cellular response to type II interferon [GO:0071346]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519] actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018] actin binding [GO:0003779]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723] 0 5.6922 AGLAPLEVR 0 0 0 0 0 0 10.5276 0 8.74359 0 0 8.94951 12.1996 0 0 0 0 0 8.62669 10.6812 9.51296 9.10737 8.92861 11.9196 0 10.2518 11.2306 O75376 NCOR1_HUMAN Nuclear receptor corepressor 1 (N-CoR) (N-CoR1) NCOR1 KIAA1047 Homo sapiens (Human) chromatin organization [GO:0006325]; locomotor rhythm [GO:0045475]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of fatty acid metabolic process [GO:0045922]; negative regulation of glycolytic process [GO:0045820]; negative regulation of JNK cascade [GO:0046329]; negative regulation of miRNA transcription [GO:1902894]; negative regulation of transcription by RNA polymerase II [GO:0000122]; spindle assembly [GO:0051225] chromatin [GO:0000785]; cytosol [GO:0005829]; histone deacetylase complex [GO:0000118]; membrane [GO:0016020]; mitotic spindle [GO:0072686]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription repressor complex [GO:0017053] histone deacetylase binding [GO:0042826]; nuclear receptor binding [GO:0016922]; nuclear thyroid hormone receptor binding [GO:0046966]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription cis-regulatory region binding [GO:0000976]; transcription corepressor activity [GO:0003714] 0.96937 -4.9375 DEEEKDEKEDSK 0 8.66991 0 9.22795 0 0 0 0 0 0 8.83393 9.71239 0 0 0 0 0 0 0 0 0 0 10.2354 10.3585 0 11.4906 0 O75380 NDUS6_HUMAN "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (Complex I-13kD-A) (CI-13kD-A) (NADH-ubiquinone oxidoreductase 13 kDa-A subunit)" NDUFS6 Homo sapiens (Human) "aerobic respiration [GO:0009060]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]" mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex I [GO:0005747] electron transfer activity [GO:0009055]; NADH dehydrogenase (ubiquinone) activity [GO:0008137] 0.92682 -1.2073 LLNRCGEAAR 12.8872 12.9736 12.7226 0 11.2212 0 12.3946 12.5639 12.6468 12.7272 12.8489 12.8871 0 0 0 0 11.7072 0 0 0 0 0 0 0 0 0 0 O75382 TRIM3_HUMAN Tripartite motif-containing protein 3 (EC 2.3.2.27) (Brain-expressed RING finger protein) (RING finger protein 22) (RING finger protein 97) TRIM3 BERP RNF22 RNF97 Homo sapiens (Human) negative regulation of translation [GO:0017148]; nervous system development [GO:0007399]; positive regulation of toll-like receptor 3 signaling pathway [GO:0034141]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein transport [GO:0015031] cytoplasm [GO:0005737]; dendrite [GO:0030425]; early endosome [GO:0005769]; Golgi apparatus [GO:0005794] identical protein binding [GO:0042802]; translation repressor activity [GO:0030371]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.92595 -1.2124 VGSRGREK 0 0 0 0 0 0 0 0 0 0 8.97284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75385 ULK1_HUMAN Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1) ULK1 KIAA0722 Homo sapiens (Human) autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; axon extension [GO:0048675]; cellular response to nutrient levels [GO:0031669]; late nucleophagy [GO:0044805]; macroautophagy [GO:0016236]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of protein-containing complex assembly [GO:0031333]; neuron projection development [GO:0031175]; neuron projection regeneration [GO:0031102]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; piecemeal microautophagy of the nucleus [GO:0034727]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of autophagy [GO:0010508]; protein autophosphorylation [GO:0046777]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; regulation of macroautophagy [GO:0016241]; regulation of protein lipidation [GO:1903059]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to starvation [GO:0042594]; reticulophagy [GO:0061709]; signal transduction [GO:0007165] Atg1/ULK1 kinase complex [GO:1990316]; autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; omegasome membrane [GO:1903349]; phagophore assembly site [GO:0000407]; phagophore assembly site membrane [GO:0034045]; recycling endosome [GO:0055037] ATP binding [GO:0005524]; GTPase binding [GO:0051020]; identical protein binding [GO:0042802]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein-containing complex binding [GO:0044877]; small GTPase binding [GO:0031267] 0.84762 0.1705 TLVPTIPR 0 0 0 0 0 0 9.33811 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75386 TULP3_HUMAN Tubby-related protein 3 (Tubby-like protein 3) TULP3 TUBL3 Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; bone development [GO:0060348]; brain development [GO:0007420]; bronchus morphogenesis [GO:0060434]; central nervous system neuron differentiation [GO:0021953]; embryonic camera-type eye development [GO:0031076]; embryonic digit morphogenesis [GO:0042733]; embryonic neurocranium morphogenesis [GO:0048702]; G protein-coupled receptor signaling pathway [GO:0007186]; ganglion development [GO:0061548]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621]; negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning [GO:0021914]; neural tube closure [GO:0001843]; protein localization to cilium [GO:0061512]; regulation of DNA-templated transcription [GO:0006355]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] 9+0 non-motile cilium [GO:0097731]; axoneme [GO:0005930]; ciliary base [GO:0097546]; cilium [GO:0005929]; extracellular region [GO:0005576]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] "enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; intraciliary transport particle A binding [GO:0120160]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein-containing complex binding [GO:0044877]" 0.96903 -4.2277 DKRGMDR 0 9.47927 0 0 9.4204 0 0 0 9.5228 0 0 11.1684 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75387 LAT3_HUMAN Large neutral amino acids transporter small subunit 3 (L-type amino acid transporter 3) (Prostate cancer overexpressed gene 1 protein) (Solute carrier family 43 member 1) SLC43A1 LAT3 PB39 POV1 Homo sapiens (Human) amino acid transport [GO:0006865]; isoleucine transport [GO:0015818]; L-valine transmembrane transport [GO:1903785]; leucine transport [GO:0015820]; negative regulation of amino acid transport [GO:0051956]; negative regulation of leucine import [GO:0060358]; neutral amino acid transport [GO:0015804] apical plasma membrane [GO:0016324]; endoplasmic reticulum membrane [GO:0005789]; plasma membrane [GO:0005886]; podocyte foot [GO:0098846] amino acid transmembrane transporter activity [GO:0015171]; L-amino acid transmembrane transporter activity [GO:0015179]; L-isoleucine transmembrane transporter activity [GO:0015188]; L-leucine transmembrane transporter activity [GO:0015190]; L-valine transmembrane transporter activity [GO:0005304]; neutral L-amino acid transmembrane transporter activity [GO:0015175] 0.95531 -1.5612 GTSENLPERSVPLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2583 0 0 0 0 0 0 0 10.5808 0 0 O75390 CISY_HUMAN "Citrate synthase, mitochondrial (EC 2.3.3.1) (Citrate (Si)-synthase)" CS Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099] extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634] citrate (Si)-synthase activity [GO:0004108]; RNA binding [GO:0003723] 0 3.9733 ALGFPLERPK 8.90635 8.79312 8.76484 0 0 0 9.94916 9.76334 9.90641 9.15636 9.31508 14.8308 9.82023 8.94615 9.22451 11.1764 10.0917 10.0995 9.06469 0 0 0 0 0 10.9951 11.1049 11.4015 O75396 SC22B_HUMAN Vesicle-trafficking protein SEC22b (ER-Golgi SNARE of 24 kDa) (ERS-24) (ERS24) (SEC22 vesicle-trafficking protein homolog B) (SEC22 vesicle-trafficking protein-like 1) SEC22B SEC22L1 Homo sapiens (Human) "endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; negative regulation of autophagosome assembly [GO:1902902]; positive regulation of protein catabolic process [GO:0045732]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; vesicle fusion with Golgi apparatus [GO:0048280]" endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; melanosome [GO:0042470]; phagocytic vesicle membrane [GO:0030670]; SNARE complex [GO:0031201]; transport vesicle [GO:0030133] SNAP receptor activity [GO:0005484] 0.022321 1.5661 ANNLSSLSK 0 0 0 0 0 0 0 0 0 0 0 0 10.7189 0 0 0 0 0 0 0 0 0 0 9.81433 0 0 0 O75400 PR40A_HUMAN Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6) PRPF40A FBP11 FLAF1 FNBP3 HIP10 HYPA HSPC225 Homo sapiens (Human) "cell cycle [GO:0007049]; cell division [GO:0051301]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; regulation of cell shape [GO:0008360]; regulation of cytokinesis [GO:0032465]" membrane [GO:0016020]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; U1 snRNP [GO:0005685]; U2-type prespliceosome [GO:0071004] RNA binding [GO:0003723] 0.89017 -0.48174 EEKEEARSK 0 0 11.7148 0 0 0 0 0 11.8604 0 0 0 0 0 0 9.68099 0 0 0 9.77808 0 0 0 0 0 0 0 O75410 TACC1_HUMAN Transforming acidic coiled-coil-containing protein 1 (Gastric cancer antigen Ga55) (Taxin-1) TACC1 KIAA1103 Homo sapiens (Human) cell division [GO:0051301]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; microtubule cytoskeleton organization [GO:0000226]; mitotic spindle organization [GO:0007052] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; nucleus [GO:0005634] nuclear estrogen receptor binding [GO:0030331]; nuclear glucocorticoid receptor binding [GO:0035259]; nuclear receptor binding [GO:0016922]; nuclear receptor coactivator activity [GO:0030374]; nuclear retinoic acid receptor binding [GO:0042974]; nuclear retinoid X receptor binding [GO:0046965]; nuclear thyroid hormone receptor binding [GO:0046966]; peroxisome proliferator activated receptor binding [GO:0042975] 0.91867 -0.88943 LITSGCKVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.47139 0 0 0 0 0 0 0 0 O75417 DPOLQ_HUMAN DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta) POLQ POLH Homo sapiens (Human) base-excision repair [GO:0006284]; DNA damage response [GO:0006974]; DNA repair [GO:0006281]; DNA-templated DNA replication [GO:0006261]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; protein homooligomerization [GO:0051260]; somatic hypermutation of immunoglobulin genes [GO:0016446] chromosome [GO:0005694]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654] 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; single-stranded DNA helicase activity [GO:0017116] 0.88821 -0.40716 EKPGASQNEGK 0 0 0 0 0 0 0 0 0 0 10.7608 9.5548 9.80587 0 0 0 0 0 0 0 0 0 0 10.9987 0 9.01413 9.2669 O75420 GGYF1_HUMAN GRB10-interacting GYF protein 1 (PERQ amino acid-rich with GYF domain-containing protein 1) GIGYF1 CDS2 PERQ1 PP3360 Homo sapiens (Human) insulin-like growth factor receptor signaling pathway [GO:0048009] cytosol [GO:0005829]; protein-containing complex [GO:0032991] 0.95214 -1.4755 CRAPEGFEEDK 0 0 0 0 9.05566 0 0 0 0 9.0886 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75425 MSPD3_HUMAN Motile sperm domain-containing protein 3 MOSPD3 Homo sapiens (Human) heart development [GO:0007507] cytoplasm [GO:0005737]; membrane [GO:0016020] 0.8097 0.23272 VLCTAPAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.52718 0 0 O75427 LRCH4_HUMAN Leucine-rich repeat and calponin homology domain-containing protein 4 (Leucine-rich repeat neuronal protein 4) (Leucine-rich neuronal protein) LRCH4 LRN LRRN1 LRRN4 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; nervous system development [GO:0007399] cytoplasm [GO:0005737]; PML body [GO:0016605] 0.76412 0.28114 SVPFIHVPSPAVPK 0 0 0 0 0 0 0 0 0 13.0835 13.0329 0 10.5199 10.7848 0 0 11.4398 0 0 0 0 0 0 0 0 0 0 O75436 VP26A_HUMAN Vacuolar protein sorting-associated protein 26A (Vesicle protein sorting 26A) (hVPS26) VPS26A VPS26 Homo sapiens (Human) "endocytic recycling [GO:0032456]; intracellular protein transport [GO:0006886]; regulation of macroautophagy [GO:0016241]; retrograde transport, endosome to Golgi [GO:0042147]" "cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; endosome membrane [GO:0010008]; lysosome [GO:0005764]; retromer complex [GO:0030904]; retromer, cargo-selective complex [GO:0030906]; tubular endosome [GO:0097422]; vesicle [GO:0031982]" 0.80891 0.23199 ELALPGELTQSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.74843 0 0 10.1013 0 0 0 0 0 0 10.0052 0 O75443 TECTA_HUMAN Alpha-tectorin TECTA Homo sapiens (Human) cell-matrix adhesion [GO:0007160]; sensory perception of sound [GO:0007605] extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; plasma membrane [GO:0005886] extracellular matrix structural constituent [GO:0005201] 0.95905 -1.7727 ELSVEVNGYK 0 0 0 0 0 0 0 0 0 0 0 0 9.75248 0 0 0 0 0 0 0 0 0 9.28714 10.3921 0 0 0 O75445 USH2A_HUMAN Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) USH2A Homo sapiens (Human) establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; periciliary membrane compartment [GO:1990075]; photoreceptor connecting cilium [GO:0032391]; photoreceptor inner segment [GO:0001917]; stereocilia ankle link [GO:0002141]; stereocilia ankle link complex [GO:0002142]; stereocilium bundle [GO:0032421]; stereocilium membrane [GO:0060171]; USH2 complex [GO:1990696] collagen binding [GO:0005518]; identical protein binding [GO:0042802]; myosin binding [GO:0017022] 0.50097 0.61213 AWGNQTIQADEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.6248 0 0 0 0 0 0 0 10.138 0 0 0 9.33805 O75452 RDH16_HUMAN Retinol dehydrogenase 16 (EC 1.1.1.105) (EC 1.1.1.209) (EC 1.1.1.315) (EC 1.1.1.53) (Human epidermal retinol dehydrogenase) (hRDH-E) (Microsomal NAD(+)-dependent retinol dehydrogenase 4) (RoDH-4) (Short chain dehydrogenase/reductase family 9C member 8) (Sterol/retinol dehydrogenase) RDH16 RODH4 SDR9C8 Homo sapiens (Human) lipid metabolic process [GO:0006629]; retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202] endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231] "11-cis-retinol dehydrogenase [GO:0106429]; androstan-3-alpha,17-beta-diol dehydrogenase activity [GO:0047044]; androsterone dehydrogenase activity [GO:0047023]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD-retinol dehydrogenase activity [GO:0004745]" 0.51711 0.59843 SFLEIWDR 0 0 0 0 0 0 0 0 0 9.30469 0 0 9.60605 0 0 0 0 0 0 0 9.91244 0 0 0 0 0 0 O75459 PAGE1_HUMAN P antigen family member 1 (PAGE-1) (AL5) (G antigen 9) (GAGE-9) (G antigen family B member 1) (Prostate-associated gene 1 protein) PAGE1 GAGE9 GAGEB1 Homo sapiens (Human) 0.87817 0.0036465 LPAEGPEPEADSQEQVHPK 0 10.627 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75460 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) (hIRE1p) (Ire1-alpha) (IRE1a) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)] ERN1 IRE1 Homo sapiens (Human) "cellular response to glucose stimulus [GO:0071333]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to unfolded protein [GO:0034620]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; endothelial cell proliferation [GO:0001935]; insulin metabolic process [GO:1901142]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; IRE1-mediated unfolded protein response [GO:0036498]; mRNA catabolic process [GO:0006402]; mRNA cleavage [GO:0006379]; mRNA cleavage involved in mRNA processing [GO:0098787]; mRNA splicing, via endonucleolytic cleavage and ligation [GO:0070054]; peptidyl-serine autophosphorylation [GO:0036289]; peptidyl-serine trans-autophosphorylation [GO:1990579]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of RNA splicing [GO:0033120]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of macroautophagy [GO:0016241]; response to endoplasmic reticulum stress [GO:0034976]" AIP1-IRE1 complex [GO:1990597]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Ire1 complex [GO:1990332]; IRE1-RACK1-PP2A complex [GO:1990630]; IRE1-TRAF2-ASK1 complex [GO:1990604]; mitochondrion [GO:0005739]; nuclear inner membrane [GO:0005637] ADP binding [GO:0043531]; ATP binding [GO:0005524]; enzyme binding [GO:0019899]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; platelet-derived growth factor receptor binding [GO:0005161]; protein homodimerization activity [GO:0042803]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; RNA endonuclease activity [GO:0004521]; unfolded protein binding [GO:0051082] 0.91731 -0.85656 ENITVPLQTDLR 0 0 0 0 0 0 0 0 0 9.91519 10.0399 10.1463 0 0 8.94413 9.23391 0 0 0 0 9.09777 0 0 0 0 9.82774 0 O75462 CRLF1_HUMAN Cytokine receptor-like factor 1 (Cytokine-like factor 1) (CLF-1) (ZcytoR5) CRLF1 UNQ288/PRO327 Homo sapiens (Human) cytokine-mediated signaling pathway [GO:0019221]; negative regulation of motor neuron apoptotic process [GO:2000672]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; ureteric bud development [GO:0001657] CRLF-CLCF1 complex [GO:0097058]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; receptor complex [GO:0043235] cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896] 0.83057 0.20296 LPPELSR 9.54875 0 9.2167 0 0 0 0 8.83551 0 0 9.32569 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75469 NR1I2_HUMAN Nuclear receptor subfamily 1 group I member 2 (Orphan nuclear receptor PAR1) (Orphan nuclear receptor PXR) (Pregnane X receptor) (Steroid and xenobiotic receptor) (SXR) NR1I2 PXR Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; signal transduction [GO:0007165]; steroid metabolic process [GO:0008202]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805]; xenobiotic transport [GO:0042908] chromatin [GO:0000785]; intermediate filament cytoskeleton [GO:0045111]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; transcription regulator complex [GO:0005667] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; nuclear receptor activity [GO:0004879]; nuclear receptor binding [GO:0016922]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]; zinc ion binding [GO:0008270]" 0.6924 0.3846 ATGYHFNVMTCEGCK 0 0 0 0 9.49721 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75475 PSIP1_HUMAN PC4 and SFRS1-interacting protein (CLL-associated antigen KW-7) (Dense fine speckles 70 kDa protein) (DFS 70) (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52) PSIP1 DFS70 LEDGF PSIP2 Homo sapiens (Human) chromatin remodeling [GO:0006338]; mRNA 5'-splice site recognition [GO:0000395]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979] cytosol [GO:0005829]; euchromatin [GO:0000791]; heterochromatin [GO:0000792]; nuclear periphery [GO:0034399]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; DNA-binding transcription factor binding [GO:0140297]; RNA binding [GO:0003723]; supercoiled DNA binding [GO:0097100]; transcription coactivator activity [GO:0003713] 0.96992 -3.0844 KGQEEKQPK 0 0 0 0 0 0 0 0 0 0 0 10.9384 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.47324 O75477 ERLN1_HUMAN Erlin-1 (Endoplasmic reticulum lipid raft-associated protein 1) (Protein KE04) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1) (SPFH domain-containing protein 1) ERLIN1 C10orf69 KE04 KEO4 SPFH1 Homo sapiens (Human) cholesterol metabolic process [GO:0008203]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of fatty acid biosynthetic process [GO:0045717]; regulation of cholesterol biosynthetic process [GO:0045540]; SREBP signaling pathway [GO:0032933]; ubiquitin-dependent ERAD pathway [GO:0030433] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane raft [GO:0045121]; protein-containing complex [GO:0032991] cholesterol binding [GO:0015485]; ubiquitin protein ligase binding [GO:0031625] 0.9687 -3.3466 FQQKVMEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0189 0 O75478 TAD2A_HUMAN Transcriptional adapter 2-alpha (Transcriptional adapter 2-like) (ADA2-like protein) TADA2A TADA2L KL04P Homo sapiens (Human) chromatin remodeling [GO:0006338]; histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of DNA-templated transcription [GO:0006355]; regulation of embryonic development [GO:0045995]; regulation of histone acetylation [GO:0035065]; regulation of histone deacetylation [GO:0031063]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tubulin deacetylation [GO:0090043] ATAC complex [GO:0140672]; mitotic spindle [GO:0072686]; nucleus [GO:0005634]; SAGA complex [GO:0000124]; SAGA-type complex [GO:0070461] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; zinc ion binding [GO:0008270] 0.96923 -3.2061 EVQDLYETMRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0736 0 0 0 0 0 0 0 0 0 0 0 0 O75487 GPC4_HUMAN Glypican-4 (K-glypican) [Cleaved into: Secreted glypican-4] GPC4 UNQ474/PRO937 Homo sapiens (Human) cell migration [GO:0016477]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of presynapse assembly [GO:1905606]; regulation of signal transduction [GO:0009966]; synaptic membrane adhesion [GO:0099560]; Wnt signaling pathway [GO:0016055] cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi lumen [GO:0005796]; lysosomal lumen [GO:0043202]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202] "coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway [GO:1904929]" 0.92311 -1.0739 LVTDVKEK 11.2632 10.957 10.8584 9.15821 0 10.2554 9.94256 0 10.5039 10.6143 11.2106 11.0924 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75521 ECI2_HUMAN "Enoyl-CoA delta isomerase 2 (EC 5.3.3.8) (DRS-1) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (Diazepam-binding inhibitor-related protein 1) (DBI-related protein 1) (Dodecenoyl-CoA isomerase) (Hepatocellular carcinoma-associated antigen 88) (Peroxisomal 3,2-trans-enoyl-CoA isomerase) (pECI) (Renal carcinoma antigen NY-REN-1)" ECI2 DRS1 HCA88 PECI Homo sapiens (Human) fatty acid beta-oxidation [GO:0006635]; fatty acid catabolic process [GO:0009062] cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777] delta(3)-delta(2)-enoyl-CoA isomerase activity [GO:0004165]; fatty-acyl-CoA binding [GO:0000062] 0.96192 -2.0463 DPGNEVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.88096 0 0 0 0 0 O75526 RMXL2_HUMAN "RNA-binding motif protein, X-linked-like-2 (Testis-specific heterogeneous nuclear ribonucleoprotein G-T) (hnRNP G-T)" RBMXL2 HNRNPGT Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]" U12-type spliceosomal complex [GO:0005689] mRNA binding [GO:0003729]; snRNA binding [GO:0017069] 0.65619 0.39526 GGGGGPR 0 0 8.9163 0 9.48339 8.39172 8.7909 9.52851 10.4297 8.72424 10.5541 10.5529 0 9.55779 8.71949 0 0 0 0 10.0646 9.23463 0 0 0 0 0 0 O75531 BAF_HUMAN "Barrier-to-autointegration factor (Breakpoint cluster region protein 1) [Cleaved into: Barrier-to-autointegration factor, N-terminally processed]" BANF1 BAF BCRG1 Homo sapiens (Human) chromatin organization [GO:0006325]; DNA integration [GO:0015074]; mitotic nuclear membrane reassembly [GO:0007084]; negative regulation of innate immune response [GO:0045824]; negative regulation of protein ADP-ribosylation [GO:0010836]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; response to oxidative stress [GO:0006979]; response to virus [GO:0009615] chromatin [GO:0000785]; condensed chromosome [GO:0000793]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; molecular function inhibitor activity [GO:0140678]; protein homodimerization activity [GO:0042803] 0.86132 0.091661 DCFGCLREWCDAFL 9.75323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75533 SF3B1_HUMAN Splicing factor 3B subunit 1 (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155) SF3B1 SAP155 Homo sapiens (Human) "chromatin remodeling [GO:0006338]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal complex assembly [GO:0000245]; U2-type prespliceosome assembly [GO:1903241]" B-WICH complex [GO:0110016]; catalytic step 2 spliceosome [GO:0071013]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U11/U12 snRNP [GO:0034693]; U12-type spliceosomal complex [GO:0005689]; U2 snRNP [GO:0005686]; U2-type precatalytic spliceosome [GO:0071005]; U2-type prespliceosome [GO:0071004]; U2-type spliceosomal complex [GO:0005684] mRNA binding [GO:0003729]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935] 0.93364 -1.2823 IADREDEYKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.73554 O75534 CSDE1_HUMAN Cold shock domain-containing protein E1 (N-ras upstream gene protein) (Protein UNR) CSDE1 D1S155E KIAA0885 NRU UNR Homo sapiens (Human) "CRD-mediated mRNA stabilization [GO:0070934]; IRES-dependent viral translational initiation [GO:0075522]; male gonad development [GO:0008584]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; positive regulation of cytoplasmic translation [GO:2000767]; regulation of translational initiation [GO:0006446]; stress granule assembly [GO:0034063]" CRD-mediated mRNA stability complex [GO:0070937]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; mCRD-mediated mRNA stability complex [GO:0106002]; P-body [GO:0000932]; plasma membrane [GO:0005886] RNA binding [GO:0003723]; RNA stem-loop binding [GO:0035613] 0.86608 0.073693 GDLETLQPGDDVEFTIK 0 10.7571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75541 ZN821_HUMAN Zinc finger protein 821 ZNF821 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837] 0.96007 -1.9362 LEKMDMMLR 0 10.7715 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75558 STX11_HUMAN Syntaxin-11 STX11 Homo sapiens (Human) exocytosis [GO:0006887]; intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; vesicle docking [GO:0048278] endomembrane system [GO:0012505]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; presynaptic active zone membrane [GO:0048787]; SNARE complex [GO:0031201]; synaptic vesicle [GO:0008021] SNAP receptor activity [GO:0005484]; SNARE binding [GO:0000149] 0.83674 0.18827 DIRDIQDENQLLVADVK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1404 0 0 0 0 8.5862 0 8.66302 0 0 0 0 0 0 O75563 SKAP2_HUMAN Src kinase-associated phosphoprotein 2 (Pyk2/RAFTK-associated protein) (Retinoic acid-induced protein 70) (SKAP55 homolog) (SKAP-55HOM) (SKAP-HOM) (Src family-associated phosphoprotein 2) (Src kinase-associated phosphoprotein 55-related protein) (Src-associated adapter protein with PH and SH3 domains) SKAP2 PRAP RA70 SAPS SCAP2 SKAP55R Homo sapiens (Human) B cell activation [GO:0042113]; negative regulation of cell population proliferation [GO:0008285]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] 0.96307 -2.0905 RIYQFTAASPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2121 0 0 0 0 0 0 0 0 0 0 0 O75564 JERKY_HUMAN Jerky protein homolog JRK JH8 Homo sapiens (Human) positive regulation of canonical Wnt signaling pathway [GO:0090263] cytoplasm [GO:0005737]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] DNA binding [GO:0003677]; mRNA binding [GO:0003729] 0.88724 -0.34489 IDICTRLEK 0 0 0 0 0 0 0 0 0 0 10.3789 0 0 0 0 0 0 0 0 9.8952 0 0 9.49649 0 0 0 0 O75570 RF1M_HUMAN "Peptide chain release factor 1, mitochondrial (MRF-1) (MtRF-1)" MTRF1 Homo sapiens (Human) mitochondrial translational termination [GO:0070126]; regulation of translational termination [GO:0006449] mitochondrion [GO:0005739] translation release factor activity [GO:0003747] 0.95532 -1.58 KLQVGTR 0 0 9.17612 0 0 0 8.81724 0 0 0 0 0 0 0 0 0 0 9.07965 0 0 0 0 0 0 0 0 0 O75578 ITA10_HUMAN Integrin alpha-10 ITGA10 UNQ468/PRO827 Homo sapiens (Human) cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; integrin-mediated signaling pathway [GO:0007229] external side of plasma membrane [GO:0009897]; integrin alpha10-beta1 complex [GO:0034680]; integrin complex [GO:0008305]; plasma membrane [GO:0005886] collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; integrin binding [GO:0005178]; metal ion binding [GO:0046872] 0.9678 -2.9533 APFVVRGGRR 0 0 0 0 0 0 0 0 9.81625 0 0 0 0 0 0 0 0 0 9.57118 9.4694 0 0 0 0 0 0 10.885 O75581 LRP6_HUMAN Low-density lipoprotein receptor-related protein 6 (LRP-6) LRP6 Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; synapse [GO:0045202]; Wnt signalosome [GO:1990909]; Wnt-Frizzled-LRP5/6 complex [GO:1990851] coreceptor activity involved in canonical Wnt signaling pathway [GO:1904928]; coreceptor activity involved in Wnt signaling pathway [GO:0071936]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; kinase inhibitor activity [GO:0019210]; low-density lipoprotein particle receptor activity [GO:0005041]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; toxin transmembrane transporter activity [GO:0019534]; Wnt receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147] 0.89871 -0.59822 QLYWIDSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.99915 O75582 KS6A5_HUMAN Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RSKL) RPS6KA5 MSK1 Homo sapiens (Human) axon guidance [GO:0007411]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production [GO:0001818]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-translational protein modification [GO:0043687]; protein phosphorylation [GO:0006468]; regulation of DNA-templated transcription [GO:0006355]; regulation of postsynapse organization [GO:0099175] cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; histone H2AS1 kinase activity [GO:0044024]; histone H3S10 kinase activity [GO:0035175]; histone H3S28 kinase activity [GO:0044022]; magnesium ion binding [GO:0000287]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713] 0.96167 -2.0519 AKTTEHTR 0 0 0 0 0 9.06676 0 0 11.9957 0 0 0 0 0 0 0 0 0 9.85414 0 0 0 0 0 0 0 0 O75592 MYCB2_HUMAN E3 ubiquitin-protein ligase MYCBP2 (EC 2.3.2.33) (Myc-binding protein 2) (Protein associated with Myc) MYCBP2 KIAA0916 PAM Homo sapiens (Human) axon guidance [GO:0007411]; branchiomotor neuron axon guidance [GO:0021785]; central nervous system projection neuron axonogenesis [GO:0021952]; circadian regulation of gene expression [GO:0032922]; negative regulation of protein catabolic process [GO:0042177]; neuromuscular process [GO:0050905]; positive regulation of protein ubiquitination [GO:0031398]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; regulation of axon guidance [GO:1902667]; regulation of cytoskeleton organization [GO:0051493]; regulation of protein localization [GO:0032880]; regulation of synaptic assembly at neuromuscular junction [GO:0008582] axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] guanyl-nucleotide exchange factor activity [GO:0005085]; identical protein binding [GO:0042802]; small GTPase binding [GO:0031267]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.96887 -4.4461 AVPVSQKK 12.085 0 0 10.444 0 10.5096 0 0 0 0 11.3788 0 11.6107 11.857 0 0 0 0 0 0 9.02306 10.8194 9.29336 0 0 9.20491 0 O75596 CLC3A_HUMAN C-type lectin domain family 3 member A (C-type lectin superfamily member 1) (Cartilage-derived C-type lectin) CLEC3A CLECSF1 UNQ700/PRO1345 Homo sapiens (Human) ossification [GO:0001503]; skeletal system development [GO:0001501] extracellular space [GO:0005615] carbohydrate binding [GO:0030246] 0.64932 0.39598 AQPNGGK 8.55021 0 0 0 0 0 0 8.81989 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5055 0 0 0 O75604 UBP2_HUMAN Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.4.19.12) (41 kDa ubiquitin-specific protease) (Deubiquitinating enzyme 2) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) USP2 UBP41 Homo sapiens (Human) cell cycle [GO:0007049]; circadian behavior [GO:0048512]; circadian regulation of gene expression [GO:0032922]; entrainment of circadian clock by photoperiod [GO:0043153]; locomotor rhythm [GO:0045475]; muscle organ development [GO:0007517]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of mitotic cell cycle [GO:0045931]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of signal transduction by p53 class mediator [GO:1901796]; ubiquitin-dependent protein catabolic process [GO:0006511] centrosome [GO:0005813]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471] cyclin binding [GO:0030332]; cysteine-type deubiquitinase activity [GO:0004843]; cysteine-type endopeptidase activity [GO:0004197]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; ubiquitin protein ligase binding [GO:0031625] 0.92184 -1.1263 FVGYNQQDAQEFLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.98982 0 0 0 0 0 0 0 0 O75607 NPM3_HUMAN Nucleoplasmin-3 NPM3 Homo sapiens (Human) chromatin remodeling [GO:0006338]; rRNA processing [GO:0006364]; rRNA transcription [GO:0009303] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] chromatin binding [GO:0003682]; histone binding [GO:0042393]; RNA binding [GO:0003723] 0 60.162 AAGTAAALAFLSQESR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.42612 9.28529 9.14878 O75610 LFTY1_HUMAN Left-right determination factor 1 (Left-right determination factor B) (Protein lefty-1) (Protein lefty-B) LEFTY1 LEFTB LEFTYB UNQ278/PRO317 Homo sapiens (Human) BMP signaling pathway [GO:0030509]; determination of left/right symmetry [GO:0007368]; heart morphogenesis [GO:0003007]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179] extracellular space [GO:0005615] cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; transforming growth factor beta receptor binding [GO:0005160] 0.58655 0.4687 LPPNSELVQAVLR 8.8107 0 0 0 0 0 0 0 0 0 10.9163 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75618 DEDD_HUMAN Death effector domain-containing protein (DEDPro1) (Death effector domain-containing testicular molecule) (FLDED-1) DEDD DEDPRO1 DEFT KE05 Homo sapiens (Human) decidualization [GO:0046697]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901837]; regulation of apoptotic process [GO:0042981]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; nucleolus [GO:0005730] DNA binding [GO:0003677] 0.81283 0.22263 DLGSIICDIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.99181 0 0 0 0 0 0 0 0 0 0 O75626 PRDM1_HUMAN PR domain zinc finger protein 1 (EC 2.1.1.-) (BLIMP-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1) (Positive regulatory domain I-binding factor 1) (PRDI-BF1) (PRDI-binding factor 1) PRDM1 BLIMP1 Homo sapiens (Human) adaptive immune response [GO:0002250]; aorta development [GO:0035904]; artery morphogenesis [GO:0048844]; cell fate commitment [GO:0045165]; coronary vasculature development [GO:0060976]; eye photoreceptor cell development [GO:0042462]; germ cell development [GO:0007281]; heart valve development [GO:0003170]; innate immune response [GO:0045087]; intestinal epithelial cell development [GO:0060576]; kidney development [GO:0001822]; maternal placenta development [GO:0001893]; morphogenesis of a branching structure [GO:0001763]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-arginine methylation [GO:0018216]; positive regulation of gene expression [GO:0010628]; post-embryonic development [GO:0009791]; regulation of cell population proliferation [GO:0042127]; regulation of extrathymic T cell differentiation [GO:0033082]; regulation of natural killer cell differentiation [GO:0032823]; regulation of NK T cell differentiation [GO:0051136]; regulation of transcription by RNA polymerase II [GO:0006357]; response to radiation [GO:0009314]; retinal bipolar neuron differentiation [GO:0060040]; sebum secreting cell proliferation [GO:1990654]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281] cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; histone methyltransferase binding [GO:1990226]; metal ion binding [GO:0046872]; methyltransferase activity [GO:0008168]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.94062 -1.3283 LDICLEKRVGTTLAAPK 0 0 0 0 0 0 0 0 0 0 0 9.8916 0 0 0 0 0 0 0 0 0 0 0 10.6128 0 0 0 O75628 REM1_HUMAN GTP-binding protein REM 1 (GTPase-regulating endothelial cell sprouting) (Rad and Gem-like GTP-binding protein 1) REM1 GES REM Homo sapiens (Human) negative regulation of high voltage-gated calcium channel activity [GO:1901842] plasma membrane [GO:0005886] calcium channel regulator activity [GO:0005246]; calmodulin binding [GO:0005516]; GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.74907 0.31281 TLNTEQEAK 0 0 12.9983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75631 UPK3A_HUMAN Uroplakin-3a (UP3a) (Uroplakin III) (UPIII) UPK3A UPK3 Homo sapiens (Human) cell morphogenesis [GO:0000902]; epithelial cell differentiation [GO:0030855]; kidney development [GO:0001822]; potassium ion homeostasis [GO:0055075]; sodium ion homeostasis [GO:0055078]; urea transport [GO:0015840]; urinary bladder development [GO:0060157]; water transport [GO:0006833] apical plasma membrane urothelial plaque [GO:0120001]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] 0.94392 -1.3361 AEVYSSKLQD 0 0 0 0 0 0 0 0 0 9.54722 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75635 SPB7_HUMAN Serpin B7 (Megsin) (TP55) SERPINB7 Homo sapiens (Human) negative regulation of endopeptidase activity [GO:0010951]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of glomerular mesangial cell proliferation [GO:0072126]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of transforming growth factor beta1 production [GO:0032914] cytoplasm [GO:0005737]; extracellular space [GO:0005615] serine-type endopeptidase inhibitor activity [GO:0004867] 0.84992 0.11675 AVAMMHQER 0 0 0 0 0 0 0 0 0 0 0 10.1361 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75636 FCN3_HUMAN Ficolin-3 (Collagen/fibrinogen domain-containing lectin 3 p35) (Collagen/fibrinogen domain-containing protein 3) (Hakata antigen) FCN3 FCNH HAKA1 Homo sapiens (Human) "cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654]" blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; serine-type endopeptidase complex [GO:1905370] antigen binding [GO:0003823]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102] 0.58737 0.46715 TFAHYATFR 8.50871 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75638 CTAG2_HUMAN Cancer/testis antigen 2 (CT2) (Autoimmunogenic cancer/testis antigen NY-ESO-2) (Cancer/testis antigen 6.2) (CT6.2) (L antigen family member 1) (LAGE-1) CTAG2 ESO2 LAGE1 Homo sapiens (Human) tRNA threonylcarbamoyladenosine metabolic process [GO:0070525] centrosome [GO:0005813]; intracellular membrane-bounded organelle [GO:0043231]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654] 0.8893 -0.44028 ASGPRGGAPRGPHGGAASAQDGR 0 0 0 11.7542 12.0013 0 0 0 0 0 9.74828 0 0 0 0 0 0 0 0 0 0 8.58811 0 0 0 0 0 O75643 U520_HUMAN U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog) (U5 snRNP-specific 200 kDa protein) (U5-200KD) SNRNP200 ASCC3L1 BRR2 HELIC2 KIAA0788 Homo sapiens (Human) "cis assembly of pre-catalytic spliceosome [GO:0000354]; mRNA splicing, via spliceosome [GO:0000398]; osteoblast differentiation [GO:0001649]; spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) [GO:0000388]" catalytic step 2 spliceosome [GO:0071013]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2-type catalytic step 1 spliceosome [GO:0071006]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.89867 -0.58815 FYDDAIVSQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6256 9.48178 0 0 9.37141 0 0 0 0 0 10.7754 0 0 O75648 MTU1_HUMAN Mitochondrial tRNA-specific 2-thiouridylase 1 (EC 2.8.1.14) (MTO2 homolog) TRMU MTU1 TRMT1 Homo sapiens (Human) tRNA wobble position uridine thiolation [GO:0002143] mitochondrion [GO:0005739] ATP binding [GO:0005524]; tRNA binding [GO:0000049]; tRNA-5-taurinomethyluridine 2-sulfurtransferase [GO:0061708] 0.89743 -0.67845 DKMMECHFR 0 0 0 0 0 0 0 0 0 0 0 0 9.69061 0 0 0 0 10.9174 0 0 0 0 0 0 0 0 0 O75663 TIPRL_HUMAN TIP41-like protein (Putative MAPK-activating protein PM10) (Type 2A-interacting protein) (TIP) TIPRL Homo sapiens (Human) DNA damage checkpoint signaling [GO:0000077]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; regulation of phosphoprotein phosphatase activity [GO:0043666]; TOR signaling [GO:0031929] cytosol [GO:0005829] 0.88302 -0.10463 LTASKTHIMKSADVEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9358 0 0 0 0 0 0 0 O75665 OFD1_HUMAN Centriole and centriolar satellite protein OFD1 (Oral-facial-digital syndrome 1 protein) (Protein 71-7A) OFD1 CXorf5 Homo sapiens (Human) cilium assembly [GO:0060271]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287] centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cilium [GO:0005929]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; motile cilium [GO:0031514]; nucleus [GO:0005634] alpha-tubulin binding [GO:0043014]; gamma-tubulin binding [GO:0043015]; identical protein binding [GO:0042802]; molecular adaptor activity [GO:0060090] 0.96911 -4.2244 ESCNMETQTSSTFNR 0 0 0 0 0 0 0 0 10.1924 0 14.4647 14.5713 9.9121 0 0 0 0 0 0 9.93807 0 10.2943 0 0 0 0 0 O75674 TM1L1_HUMAN TOM1-like protein 1 (Src-activating and signaling molecule protein) (Target of Myb-like protein 1) TOM1L1 SRCASM Homo sapiens (Human) activation of protein kinase activity [GO:0032147]; negative regulation of mitotic nuclear division [GO:0045839]; positive regulation of protein autophosphorylation [GO:0031954]; protein transport [GO:0015031]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; Golgi stack [GO:0005795]; lysosome [GO:0005764]; membrane [GO:0016020] clathrin binding [GO:0030276]; phosphatidylinositol binding [GO:0035091]; protein kinase activator activity [GO:0030295]; protein kinase binding [GO:0019901]; SH3 domain binding [GO:0017124]; ubiquitin binding [GO:0043130] 0.90671 -0.71841 EATNTTSEPSAPSQDLLDLSPSPR 11.1106 9.58457 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75676 KS6A4_HUMAN Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 4) (Nuclear mitogen- and stress-activated protein kinase 2) (Ribosomal protein kinase B) (RSKB) RPS6KA4 MSK2 Homo sapiens (Human) inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production [GO:0001818]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-translational protein modification [GO:0043687]; protein phosphorylation [GO:0006468]; regulation of DNA-templated transcription [GO:0006355] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; synapse [GO:0045202] ATP binding [GO:0005524]; histone H3S10 kinase activity [GO:0035175]; histone H3S28 kinase activity [GO:0044022]; magnesium ion binding [GO:0000287]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; ribosomal protein S6 kinase activity [GO:0004711] 0.93963 -1.3074 AGGHDAGK 0 0 0 13.6061 0 0 8.41456 0 0 0 9.26702 8.00703 0 7.84912 0 0 0 0 0 0 0 0 0 0 8.42219 0 0 O75683 SURF6_HUMAN Surfeit locus protein 6 SURF6 SURF-6 Homo sapiens (Human) ribosomal large subunit biogenesis [GO:0042273]; ribosomal small subunit biogenesis [GO:0042274] chromosome [GO:0005694]; granular component [GO:0001652]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] DNA binding [GO:0003677]; RNA binding [GO:0003723] 0.95959 -1.8264 ASLLAKDAYLQSLAK 0 8.7003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75688 PPM1B_HUMAN Protein phosphatase 1B (EC 3.1.3.16) (Protein phosphatase 2C isoform beta) (PP2C-beta) PPM1B PP2CB Homo sapiens (Human) N-terminal protein myristoylation [GO:0006499]; negative regulation of defense response to virus [GO:0050687]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein dephosphorylation [GO:0006470] cytosol [GO:0005829]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634] magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; myosin phosphatase activity [GO:0017018]; protein serine/threonine phosphatase activity [GO:0004722] 0.7601 0.29421 NVIEAVYSR 0 0 8.70722 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75689 ADAP1_HUMAN Arf-GAP with dual PH domain-containing protein 1 (Centaurin-alpha-1) (Cnt-a1) (Putative MAPK-activating protein PM25) ADAP1 CENTA1 Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; positive regulation of GTPase activity [GO:0043547]; regulation of GTPase activity [GO:0043087] cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; plasma membrane [GO:0005886] "GTPase activator activity [GO:0005096]; inositol 1,3,4,5 tetrakisphosphate binding [GO:0043533]; metal ion binding [GO:0046872]; phosphatidylinositol bisphosphate binding [GO:1902936]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]" 0.91823 -0.87184 NIFIYHEDGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3793 0 0 0 0 0 0 0 0 O75691 UTP20_HUMAN Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Novel nucleolar protein 73) (NNP73) (Protein Key-1A6) UTP20 DRIM Homo sapiens (Human) "endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000480]; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000472]; negative regulation of cell population proliferation [GO:0008285]; ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364]" "90S preribosome [GO:0030686]; cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; preribosome, small subunit precursor [GO:0030688]; small-subunit processome [GO:0032040]" RNA binding [GO:0003723] 0.96013 -1.7943 ADLFPILMR 0 0 0 0 9.10805 0 0 0 0 0 0 0 0 0 0 0 10.8338 0 0 0 0 0 9.64929 0 0 0 9.51239 O75694 NU155_HUMAN Nuclear pore complex protein Nup155 (155 kDa nucleoporin) (Nucleoporin Nup155) NUP155 KIAA0791 Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; miRNA processing [GO:0035196]; mRNA export from nucleus [GO:0006406]; nuclear envelope organization [GO:0006998]; nucleocytoplasmic transport [GO:0006913]; protein import into nucleus [GO:0006606]; protein localization to nuclear inner membrane [GO:0036228]; RNA export from nucleus [GO:0006405]; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000972] cytosol [GO:0005829]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear pore inner ring [GO:0044611] structural constituent of nuclear pore [GO:0017056] 0.79844 0.23965 ISLQAIQQLVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0411 0 0 0 0 0 0 0 0 9.15742 0 O75695 XRP2_HUMAN Protein XRP2 RP2 Homo sapiens (Human) cilium assembly [GO:0060271]; post-Golgi vesicle-mediated transport [GO:0006892]; protein folding [GO:0006457]; protein transport [GO:0015031]; visual perception [GO:0007601] centriole [GO:0005814]; ciliary basal body [GO:0036064]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; periciliary membrane compartment [GO:1990075]; plasma membrane [GO:0005886] GTP binding [GO:0005525]; GTPase activator activity [GO:0005096]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082] 0.96163 -2.0637 AEDAQRVFR 0 0 0 0 0 0 0 0 0 0 0 0 10.5582 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75715 GPX5_HUMAN Epididymal secretory glutathione peroxidase (EC 1.11.1.9) (Epididymis-specific glutathione peroxidase-like protein) (EGLP) (Glutathione peroxidase 5) (GPx-5) (GSHPx-5) GPX5 Homo sapiens (Human) cellular response to oxidative stress [GO:0034599]; lipid metabolic process [GO:0006629] extracellular region [GO:0005576] glutathione peroxidase activity [GO:0004602] 0.92722 -1.1865 SISWDPVK 10.6466 10.5736 10.9552 9.6717 9.85067 9.73867 10.4195 10.4214 10.3846 0 9.83045 9.8882 9.87667 0 9.86244 0 10.2093 9.42605 8.96671 10.1951 9.11975 9.02267 9.13866 0 9.96679 0 9.70686 O75717 WDHD1_HUMAN WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA-binding protein 1) (And-1) WDHD1 AND1 Homo sapiens (Human) DNA repair [GO:0006281]; DNA-templated DNA replication [GO:0006261]; mitotic cell cycle [GO:0000278] cytoplasm [GO:0005737]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654] chromatin binding [GO:0003682]; DNA binding [GO:0003677] 0.55986 0.54048 GQMEEQFWR 0 8.83305 0 9.12234 0 0 0 0 0 0 0 0 0 0 0 11.2572 0 0 0 0 0 0 0 0 9.99831 0 0 O75718 CRTAP_HUMAN Cartilage-associated protein CRTAP CASP Homo sapiens (Human) chaperone-mediated protein folding [GO:0061077]; collagen fibril organization [GO:0030199]; negative regulation of post-translational protein modification [GO:1901874]; peptidyl-proline hydroxylation to 3-hydroxy-L-proline [GO:0018400]; protein stabilization [GO:0050821]; spermatogenesis [GO:0007283] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991] 0.96283 -2.5207 CKQGLPAFRQSQPSR 0 0 0 0 0 0 0 0 0 9.13006 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75746 S2512_HUMAN "Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial (Araceli hiperlarga) (Aralar) (Aralar1) (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12)" SLC25A12 AGC1 ARALAR1 Homo sapiens (Human) aspartate family amino acid metabolic process [GO:0009066]; aspartate transmembrane transport [GO:0015810]; gluconeogenesis [GO:0006094]; glutamate biosynthetic process [GO:0006537]; L-glutamate transmembrane transport [GO:0015813]; malate-aspartate shuttle [GO:0043490]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of myelination [GO:0031643]; response to calcium ion [GO:0051592] membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] "3-sulfino-L-alanine: proton, glutamate antiporter activity [GO:0000514]; acidic amino acid transmembrane transporter activity [GO:0015172]; aspartate:glutamate, proton antiporter activity [GO:0000515]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; L-aspartate transmembrane transporter activity [GO:0015183]; L-glutamate transmembrane transporter activity [GO:0005313]" 0.95918 -1.952 LTLADIER 0 11.2873 0 0 0 0 0 0 0 0 10.5725 10.8629 0 0 0 0 0 0 9.33166 0 0 0 0 0 0 0 10.1888 O75747 P3C2G_HUMAN Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (PI3K-C2-gamma) (PtdIns-3-kinase C2 subunit gamma) (EC 2.7.1.137) (EC 2.7.1.154) (Phosphoinositide 3-kinase-C2-gamma) PIK3C2G Homo sapiens (Human) cell migration [GO:0016477]; chemotaxis [GO:0006935]; modulation by host of viral process [GO:0044788]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; phosphatidylinositol 3-kinase complex [GO:0005942]; plasma membrane [GO:0005886] 1-phosphatidylinositol-3-kinase activity [GO:0016303]; 1-phosphatidylinositol-4-phosphate 3-kinase activity [GO:0035005]; ATP binding [GO:0005524]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol phosphate kinase activity [GO:0016307] 0.88448 -0.2045 IKESLECFPVK 9.81799 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.7949 0 10.7628 0 0 0 0 0 0 0 0 0 O75751 S22A3_HUMAN Solute carrier family 22 member 3 (Extraneuronal monoamine transporter) (EMT) (Organic cation transporter 3) (OCT3) SLC22A3 EMTH OCT3 Homo sapiens (Human) dopamine transport [GO:0015872]; dopamine uptake [GO:0090494]; epinephrine transport [GO:0048241]; epinephrine uptake [GO:0051625]; histamine metabolic process [GO:0001692]; histamine transport [GO:0051608]; histamine uptake [GO:0051615]; monoamine transport [GO:0015844]; monoatomic ion transport [GO:0006811]; monocarboxylic acid transport [GO:0015718]; neurotransmitter transport [GO:0006836]; norepinephrine transport [GO:0015874]; norepinephrine uptake [GO:0051620]; organic anion transport [GO:0015711]; organic cation transport [GO:0015695]; purine-containing compound transmembrane transport [GO:0072530]; quaternary ammonium group transport [GO:0015697]; regulation of appetite [GO:0032098]; serotonin transport [GO:0006837]; serotonin uptake [GO:0051610]; spermidine transport [GO:0015848]; toxin transport [GO:1901998]; transport across blood-brain barrier [GO:0150104]; xenobiotic transport [GO:0042908] apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; endomembrane system [GO:0012505]; membrane [GO:0016020]; mitochondrial membrane [GO:0031966]; neuronal cell body [GO:0043025]; nuclear outer membrane [GO:0005640]; plasma membrane [GO:0005886]; presynapse [GO:0098793] monoamine transmembrane transporter activity [GO:0008504]; neurotransmitter transmembrane transporter activity [GO:0005326]; organic anion transmembrane transporter activity [GO:0008514]; organic cation transmembrane transporter activity [GO:0015101]; quaternary ammonium group transmembrane transporter activity [GO:0015651]; spermidine transmembrane transporter activity [GO:0015606]; toxin transmembrane transporter activity [GO:0019534] 0.95978 -1.9028 MPSFDEALQR 0 0 9.39034 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75752 B3GL1_HUMAN "UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 (Beta-1,3-GalNAc-T1) (EC 2.4.1.79) (Beta-1,3-galactosyltransferase 3) (Beta-1,3-GalTase 3) (Beta3Gal-T3) (Beta3GalT3) (b3Gal-T3) (Beta-3-Gx-T3) (Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase) (Globoside synthase) (UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase)" B3GALNT1 B3GALT3 UNQ531/PRO1074 Homo sapiens (Human) glycosphingolipid metabolic process [GO:0006687]; oligosaccharide biosynthetic process [GO:0009312]; protein O-linked glycosylation [GO:0006493] Golgi membrane [GO:0000139]; membrane [GO:0016020] "galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity [GO:0047273]; UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity [GO:0008499]" 0.93233 -1.2642 ARQAIRVTWGEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3892 0 0 0 0 0 0 0 0 O75762 TRPA1_HUMAN Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation-sensitive protein p120) (p120) (Wasabi receptor) TRPA1 ANKTM1 Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; cell surface receptor signaling pathway [GO:0007166]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; intracellular calcium ion homeostasis [GO:0006874]; monoatomic ion transport [GO:0006811]; protein homotetramerization [GO:0051289]; response to cold [GO:0009409]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955] plasma membrane [GO:0005886]; stereocilium bundle [GO:0032421] calcium channel activity [GO:0005262]; calcium-release channel activity [GO:0015278]; channel activity [GO:0015267]; identical protein binding [GO:0042802]; temperature-gated cation channel activity [GO:0097604] 0.80112 0.23936 SPLHFAASYGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.65612 0 0 0 O75764 TCEA3_HUMAN Transcription elongation factor A protein 3 (Transcription elongation factor S-II protein 3) (Transcription elongation factor TFIIS.h) TCEA3 TFIISH Homo sapiens (Human) DNA-templated transcription [GO:0006351]; transcription elongation by RNA polymerase II [GO:0006368] nucleus [GO:0005634] DNA binding [GO:0003677]; zinc ion binding [GO:0008270] 0.89727 -0.52649 ELRNAMTQEAIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.0114 0 0 0 0 0 0 0 0 0 O75781 PALM_HUMAN Paralemmin-1 (Paralemmin) PALM KIAA0270 Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; cellular response to electrical stimulus [GO:0071257]; cytoskeleton organization [GO:0007010]; negative regulation of adenylate cyclase activity [GO:0007194]; negative regulation of dopamine receptor signaling pathway [GO:0060160]; positive regulation of filopodium assembly [GO:0051491]; protein localization to plasma membrane [GO:0072659]; regulation of cell shape [GO:0008360]; synapse maturation [GO:0060074] apicolateral plasma membrane [GO:0016327]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cytoplasmic side of plasma membrane [GO:0009898]; cytoplasmic vesicle [GO:0031410]; dendritic spine [GO:0043197]; filopodium membrane [GO:0031527]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] D3 dopamine receptor binding [GO:0031750] 0.96683 -2.3245 APAPSPAKEER 10.0584 0 0 0 0 0 0 9.83769 9.82663 0 8.97991 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75791 GRAP2_HUMAN GRB2-related adapter protein 2 (Adapter protein GRID) (GRB-2-like protein) (GRB2L) (GRBLG) (GRBX) (Grf40 adapter protein) (Grf-40) (Growth factor receptor-binding protein) (Hematopoietic cell-associated adapter protein GrpL) (P38) (Protein GADS) (SH3-SH2-SH3 adapter Mona) GRAP2 GADS GRB2L GRID Homo sapiens (Human) cell-cell signaling [GO:0007267]; Ras protein signal transduction [GO:0007265]; regulation of MAPK cascade [GO:0043408]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] phosphotyrosine residue binding [GO:0001784] 0.78755 0.24837 HEDDVQHFK 0 0 0 0 0 0 0 9.0517 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75807 PR15A_HUMAN Protein phosphatase 1 regulatory subunit 15A (Growth arrest and DNA damage-inducible protein GADD34) (Myeloid differentiation primary response protein MyD116 homolog) PPP1R15A GADD34 Homo sapiens (Human) apoptotic process [GO:0006915]; DNA damage response [GO:0006974]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of protein dephosphorylation [GO:0035308]; positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation [GO:1903917]; positive regulation of peptidyl-serine dephosphorylation [GO:1902310]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of translational initiation in response to stress [GO:0032058]; protein localization to endoplasmic reticulum [GO:0070972]; regulation of cell cycle [GO:0051726]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to endoplasmic reticulum stress [GO:0034976] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; protein phosphatase type 1 complex [GO:0000164] protein kinase binding [GO:0019901]; protein phosphatase 1 binding [GO:0008157]; protein phosphatase activator activity [GO:0072542]; protein phosphatase regulator activity [GO:0019888] 0.89813 -0.66902 TLQGSDKNPGEEK 0 0 0 0 9.39425 9.45092 0 0 0 0 10.3662 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75815 BCAR3_HUMAN Breast cancer anti-estrogen resistance protein 3 (Novel SH2-containing protein 2) (SH2 domain-containing protein 3B) BCAR3 NSP2 SH2D3B UNQ271/PRO308 Homo sapiens (Human) endothelin receptor signaling pathway [GO:0086100]; insulin receptor signaling pathway [GO:0008286]; lens morphogenesis in camera-type eye [GO:0002089]; positive regulation of DNA replication [GO:0045740]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264] cytoplasm [GO:0005737]; focal adhesion [GO:0005925]; membrane [GO:0016020] guanyl-nucleotide exchange factor activity [GO:0005085]; kinase binding [GO:0019900]; phosphotyrosine residue binding [GO:0001784] 0.88808 -0.43217 HQYTQTAILYEK 0 0 0 0 0 0 0 0 14.8943 0 0 0 0 0 0 0 0 0 9.54471 0 0 0 0 0 10.4277 0 0 O75817 POP7_HUMAN Ribonuclease P protein subunit p20 (RNaseP protein p20) (Ribonucleases P/MRP protein subunit POP7 homolog) (hPOP7) POP7 RPP20 Homo sapiens (Human) "RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; rRNA processing [GO:0006364]; tRNA 5'-leader removal [GO:0001682]; tRNA processing [GO:0008033]" cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; multimeric ribonuclease P complex [GO:0030681]; nucleolar ribonuclease P complex [GO:0005655]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonuclease MRP complex [GO:0000172] ribonuclease P activity [GO:0004526]; ribonuclease P RNA binding [GO:0033204]; RNA binding [GO:0003723] 0.92493 -0.97377 AENREPR 0 0 0 0 0 0 0 8.37599 0 9.02162 0 0 13.8709 13.789 13.635 9.28434 0 0 0 0 0 0 0 0 0 0 0 O75818 RPP40_HUMAN Ribonuclease P protein subunit p40 (RNaseP protein p40) (RNase P subunit 1) RPP40 RNASEP1 Homo sapiens (Human) "endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; endonucleolytic cleavage involved in tRNA processing [GO:1905267]; tRNA 5'-leader removal [GO:0001682]" multimeric ribonuclease P complex [GO:0030681]; nucleolar ribonuclease P complex [GO:0005655]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonuclease MRP complex [GO:0000172] ribonuclease P activity [GO:0004526]; ribonuclease P RNA binding [GO:0033204] 0.9159 -0.84189 FDFLLAWHK 0 0 0 0 0 0 0 0 12.3763 9.63332 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75820 ZN189_HUMAN Zinc finger protein 189 ZNF189 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.86967 0.044123 LSTYLIQHQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7832 0 0 O75821 EIF3G_HUMAN Eukaryotic translation initiation factor 3 subunit G (eIF3g) (Eukaryotic translation initiation factor 3 RNA-binding subunit) (eIF-3 RNA-binding subunit) (Eukaryotic translation initiation factor 3 subunit 4) (eIF-3-delta) (eIF3 p42) (eIF3 p44) EIF3G EIF3S4 Homo sapiens (Human) formation of cytoplasmic translation initiation complex [GO:0001732]; translational initiation [GO:0006413]; viral translational termination-reinitiation [GO:0075525] cytoplasm [GO:0005737]; cytosol [GO:0005829]; eukaryotic 43S preinitiation complex [GO:0016282]; eukaryotic 48S preinitiation complex [GO:0033290]; eukaryotic translation initiation factor 3 complex [GO:0005852]; perinuclear region of cytoplasm [GO:0048471] RNA binding [GO:0003723]; translation initiation factor activity [GO:0003743] 0.7303 0.33791 ELAEQLGLSTGEK 0 0 0 0 0 0 10.4324 0 10.1165 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75822 EIF3J_HUMAN Eukaryotic translation initiation factor 3 subunit J (eIF3j) (Eukaryotic translation initiation factor 3 subunit 1) (eIF-3-alpha) (eIF3 p35) EIF3J EIF3S1 PRO0391 Homo sapiens (Human) formation of cytoplasmic translation initiation complex [GO:0001732]; translational initiation [GO:0006413] cytosol [GO:0005829]; eukaryotic 43S preinitiation complex [GO:0016282]; eukaryotic 48S preinitiation complex [GO:0033290]; eukaryotic translation initiation factor 3 complex [GO:0005852] identical protein binding [GO:0042802]; translation initiation factor activity [GO:0003743] 0.9655 -2.2969 KKGVVPGGGLK 0 0 0 0 0 0 15.6479 15.7141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75829 CNMD_HUMAN Leukocyte cell-derived chemotaxin 1 (Chondromodulin) [Cleaved into: Chondrosurfactant protein (CH-SP); Chondromodulin-1 (Chondromodulin-I) (ChM-I)] CNMD CHMI LECT1 MYETS1 Homo sapiens (Human) cartilage development [GO:0051216]; cell differentiation [GO:0030154]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; proteoglycan metabolic process [GO:0006029]; skeletal system development [GO:0001501] endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020] 0.95204 -1.476 IPEVGAVTK 0 0 0 0 0 0 0 10.0018 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75838 CIB2_HUMAN Calcium and integrin-binding family member 2 (Kinase-interacting protein 2) (KIP 2) CIB2 KIP2 Homo sapiens (Human) calcium ion homeostasis [GO:0055074]; cellular response to ATP [GO:0071318]; photoreceptor cell maintenance [GO:0045494]; positive regulation of cytosolic calcium ion concentration [GO:0007204] blood microparticle [GO:0072562]; cell periphery [GO:0071944]; cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; muscle tendon junction [GO:0005927]; neuromuscular junction [GO:0031594]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; sarcolemma [GO:0042383]; stereocilium [GO:0032420] calcium ion binding [GO:0005509]; integrin binding [GO:0005178]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803] 0.41989 0.67989 ELKANYAFKIYDFNTDNFICK 0 9.99294 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.73263 9.6009 O75843 AP1G2_HUMAN AP-1 complex subunit gamma-like 2 (Gamma2-adaptin) (G2ad) AP1G2 Homo sapiens (Human) Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] AP-1 adaptor complex [GO:0030121]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle [GO:0005798]; membrane [GO:0016020]; transport vesicle [GO:0030133] clathrin adaptor activity [GO:0035615] 0.054054 1.4021 AVEYDTLFR 10.1536 10.2377 0 0 0 0 0 9.39335 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75844 FACE1_HUMAN CAAX prenyl protease 1 homolog (EC 3.4.24.84) (Farnesylated proteins-converting enzyme 1) (FACE-1) (Prenyl protein-specific endoprotease 1) (Zinc metalloproteinase Ste24 homolog) ZMPSTE24 FACE1 STE24 Homo sapiens (Human) "adult walking behavior [GO:0007628]; bone mineralization [GO:0030282]; CAAX-box protein processing [GO:0071586]; calcium ion import into sarcoplasmic reticulum [GO:1990036]; CAMKK-AMPK signaling cascade [GO:0061762]; cardiac conduction [GO:0061337]; cardiac muscle cell development [GO:0055013]; cardiac ventricle development [GO:0003231]; cellular lipid metabolic process [GO:0044255]; cellular response to gamma radiation [GO:0071480]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; growth plate cartilage development [GO:0003417]; hair follicle development [GO:0001942]; heart morphogenesis [GO:0003007]; inflammatory cell apoptotic process [GO:0006925]; kidney morphogenesis [GO:0060993]; liver development [GO:0001889]; maintenance of rDNA [GO:0043007]; multicellular organism growth [GO:0035264]; negative regulation of miRNA processing [GO:1903799]; neuromuscular process [GO:0050905]; nuclear envelope organization [GO:0006998]; positive regulation of gene expression via CpG island demethylation [GO:0044029]; prenylated protein catabolic process [GO:0030327]; proteolysis [GO:0006508]; regulation of autophagy [GO:0010506]; regulation of bone mineralization [GO:0030500]; regulation of cell shape [GO:0008360]; regulation of cellular senescence [GO:2000772]; regulation of defense response to virus [GO:0050688]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of DNA methylation [GO:0044030]; regulation of fibroblast proliferation [GO:0048145]; regulation of glucose metabolic process [GO:0010906]; regulation of hormone metabolic process [GO:0032350]; regulation of lipid metabolic process [GO:0019216]; regulation of mitotic cell cycle DNA replication [GO:1903463]; regulation of multicellular organism growth [GO:0040014]; regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903025]; regulation of stress-activated protein kinase signaling cascade [GO:0070302]; regulation of termination of RNA polymerase I transcription [GO:2000730]; regulation of TOR signaling [GO:0032006]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to DNA damage checkpoint signaling [GO:0072423]; thymus development [GO:0048538]; ventricular cardiac muscle tissue development [GO:0003229]" early endosome membrane [GO:0031901]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; late endosome membrane [GO:0031902]; membrane [GO:0016020]; nuclear inner membrane [GO:0005637]; protein-containing complex [GO:0032991] double-stranded DNA binding [GO:0003690]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metalloexopeptidase activity [GO:0008235] 0.95135 -1.442 LKEEIEVMAK 0 0 0 0 0 0 9.0912 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75864 PPR37_HUMAN Protein phosphatase 1 regulatory subunit 37 (Leucine-rich repeat-containing protein 68) PPP1R37 KIAA1986 LRRC68 Homo sapiens (Human) protein phosphatase inhibitor activity [GO:0004864] 0.96784 -2.926 ELYLADNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9033 0 O75865 TPC6A_HUMAN Trafficking protein particle complex subunit 6A (TRAPP complex subunit 6A) TRAPPC6A HSPC289 Homo sapiens (Human) COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; regulation of GTPase activity [GO:0043087]; vesicle tethering [GO:0099022] cis-Golgi network [GO:0005801]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; trans-Golgi network [GO:0005802]; TRAPP complex [GO:0030008]; TRAPPIII protein complex [GO:1990072] 0.8942 -0.51753 DLWVAVFQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.97484 0 O75871 CEAM4_HUMAN Carcinoembryonic antigen-related cell adhesion molecule 4 (CEA cell adhesion molecule 4) (Carcinoembryonic antigen CGM7) (Non-specific cross-reacting antigen W236) CEACAM4 CGM7 Homo sapiens (Human) phagocytosis [GO:0006909]; regulation of immune system process [GO:0002682]; signal transduction [GO:0007165] cell surface [GO:0009986]; membrane [GO:0016020]; plasma membrane [GO:0005886] protein tyrosine kinase binding [GO:1990782] 0.82999 0.20656 EQPPPASTPGHGPSHR 0 10.2471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75874 IDHC_HUMAN Isocitrate dehydrogenase [NADP] cytoplasmic (IDH) (IDH1) (EC 1.1.1.42) (Cytosolic NADP-isocitrate dehydrogenase) (IDPc) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase) IDH1 PICD Homo sapiens (Human) 2-oxoglutarate metabolic process [GO:0006103]; female gonad development [GO:0008585]; glutathione metabolic process [GO:0006749]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; regulation of phospholipid biosynthetic process [GO:0071071]; regulation of phospholipid catabolic process [GO:0060696]; response to oxidative stress [GO:0006979]; response to steroid hormone [GO:0048545]; tricarboxylic acid cycle [GO:0006099] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724] cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803] 0.050526 1.4224 ATDFVVPGPGK 0 0 0 0 9.54458 0 0 0 8.85231 0 0 0 0 10.4803 0 9.85462 0 9.31168 0 0 0 10.1235 10.7803 0 9.71917 9.72219 9.65451 O75879 GATB_HUMAN "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial (Glu-AdT subunit B) (EC 6.3.5.-) (Cytochrome c oxidase assembly factor PET112 homolog)" GATB PET112 PET112L HSPC199 Homo sapiens (Human) glutaminyl-tRNAGln biosynthesis via transamidation [GO:0070681]; mitochondrial translation [GO:0032543] glutamyl-tRNA(Gln) amidotransferase complex [GO:0030956]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity [GO:0050567] 0.96407 -2.2111 EGKQDYR 0 0 0 0 0 0 0 0 9.59738 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75881 CP7B1_HUMAN Cytochrome P450 7B1 (24-hydroxycholesterol 7-alpha-hydroxylase) (EC 1.14.14.26) (25/26-hydroxycholesterol 7-alpha-hydroxylase) (EC 1.14.14.29) (3-hydroxysteroid 7-alpha hydroxylase) (Oxysterol 7-alpha-hydroxylase) CYP7B1 Homo sapiens (Human) B cell chemotaxis [GO:0035754]; bile acid biosynthetic process [GO:0006699]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; epithelial cell proliferation [GO:0050673]; intracellular estrogen receptor signaling pathway [GO:0030520]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; positive regulation of epithelial cell proliferation [GO:0050679]; prostate gland epithelium morphogenesis [GO:0060740]; sterol metabolic process [GO:0016125] endoplasmic reticulum membrane [GO:0005789] 24-hydroxycholesterol 7alpha-hydroxylase activity [GO:0033782]; 25-hydroxycholesterol 7alpha-hydroxylase activity [GO:0033783]; 27-hydroxycholesterol 7-alpha-monooxygenase activity [GO:0047092]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxysterol 7-alpha-hydroxylase activity [GO:0008396] 0.88204 -0.095709 LKCYLMPFGTGTSK 9.36313 0 0 0 0 0 0 0 0 0 0 11.3438 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75882 ATRN_HUMAN Attractin (DPPT-L) (Mahogany homolog) ATRN KIAA0548 MGCA Homo sapiens (Human) cerebellum development [GO:0021549]; inflammatory response [GO:0006954]; myelination [GO:0042552]; pigmentation [GO:0043473]; regulation of multicellular organism growth [GO:0040014]; response to oxidative stress [GO:0006979] extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886] carbohydrate binding [GO:0030246]; signaling receptor activity [GO:0038023] 0.96002 -1.7922 CQPCKCNGHASLCNTNTGK 0 0 0 0 10.9361 0 0 0 0 9.34241 0 0 0 0 0 10.4433 0 0 0 0 0 0 0 0 0 0 9.35045 O75884 RBBP9_HUMAN Serine hydrolase RBBP9 (EC 3.-.-.-) (B5T-overexpressed gene protein) (Protein BOG) (Retinoblastoma-binding protein 10) (RBBP-10) (Retinoblastoma-binding protein 9) (RBBP-9) RBBP9 BOG RBBP10 Homo sapiens (Human) positive regulation of gene expression [GO:0010628]; regulation of cell population proliferation [GO:0042127]; response to nematode [GO:0009624]; type II pneumocyte differentiation [GO:0060510] nucleoplasm [GO:0005654] hydrolase activity [GO:0016787] 0.87743 -0.0037615 IPGFQCLAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0627 O75891 AL1L1_HUMAN Cytosolic 10-formyltetrahydrofolate dehydrogenase (10-FTHFDH) (FDH) (EC 1.5.1.6) (Aldehyde dehydrogenase family 1 member L1) ALDH1L1 FTHFD Homo sapiens (Human) 10-formyltetrahydrofolate catabolic process [GO:0009258]; biosynthetic process [GO:0009058]; NADPH regeneration [GO:0006740]; one-carbon metabolic process [GO:0006730] cytosol [GO:0005829]; extracellular exosome [GO:0070062] "aldehyde dehydrogenase (NAD+) activity [GO:0004029]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]" 0.96947 -3.1348 AVAAAKDAFENGR 0 0 10.828 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.84015 0 0 0 O75897 ST1C4_HUMAN Sulfotransferase 1C4 (ST1C4) (EC 2.8.2.1) (Sulfotransferase 1C2) (SULT1C#2) SULT1C4 SULT1C2 Homo sapiens (Human) 3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; doxorubicin metabolic process [GO:0044598]; ethanol catabolic process [GO:0006068]; flavonoid metabolic process [GO:0009812]; sulfation [GO:0051923]; xenobiotic metabolic process [GO:0006805] cytoplasm [GO:0005737]; cytosol [GO:0005829] aryl sulfotransferase activity [GO:0004062]; sulfotransferase activity [GO:0008146] 0.96722 -2.9777 GAVGDWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.64339 0 9.91207 O75899 GABR2_HUMAN Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20) GABBR2 GPR51 GPRC3B Homo sapiens (Human) "adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932]" cytoplasm [GO:0005737]; G protein-coupled GABA receptor complex [GO:1902712]; G protein-coupled receptor heterodimeric complex [GO:0038039]; GABA receptor complex [GO:1902710]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211] G protein-coupled GABA receptor activity [GO:0004965]; protein heterodimerization activity [GO:0046982]; transmembrane signaling receptor activity [GO:0004888] 0.96792 -2.8872 TISGKTPQQYEREYNNK 0 0 0 0 0 9.55555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2779 0 0 9.60942 O75901 RASF9_HUMAN Ras association domain-containing protein 9 (PAM COOH-terminal interactor protein 1) (P-CIP1) (Peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor) RASSF9 PAMCI PCIP1 Homo sapiens (Human) endosomal transport [GO:0016197]; intracellular transport [GO:0046907]; protein targeting [GO:0006605]; signal transduction [GO:0007165] cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; recycling endosome [GO:0055037]; trans-Golgi network transport vesicle membrane [GO:0012510] 0.96935 -3.3995 HKNRSPTK 0 0 0 0 0 0 12.5088 0 0 0 0 9.29416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75907 DGAT1_HUMAN Diacylglycerol O-acyltransferase 1 (EC 2.3.1.20) (ACAT-related gene product 1) (Acyl-CoA retinol O-fatty-acyltransferase) (ARAT) (Retinol O-fatty-acyltransferase) (EC 2.3.1.76) (Diglyceride acyltransferase) DGAT1 AGRP1 DGAT Homo sapiens (Human) diacylglycerol metabolic process [GO:0046339]; fatty acid homeostasis [GO:0055089]; lipid storage [GO:0019915]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]; monoacylglycerol biosynthetic process [GO:0006640]; triglyceride biosynthetic process [GO:0019432]; triglyceride metabolic process [GO:0006641]; very-low-density lipoprotein particle assembly [GO:0034379] endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579] 2-acylglycerol O-acyltransferase activity [GO:0003846]; acyltransferase activity [GO:0016746]; diacylglycerol O-acyltransferase activity [GO:0004144]; identical protein binding [GO:0042802]; retinol O-fatty-acyltransferase activity [GO:0050252] 0.23629 0.8497 AASAGKK 9.34216 9.19247 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75908 SOAT2_HUMAN Sterol O-acyltransferase 2 (EC 2.3.1.26) (Acyl-coenzyme A:cholesterol acyltransferase 2) (ACAT-2) (Cholesterol acyltransferase 2) SOAT2 ACACT2 ACAT2 Homo sapiens (Human) cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol storage [GO:0010878]; intestinal cholesterol absorption [GO:0030299]; low-density lipoprotein particle clearance [GO:0034383]; macrophage derived foam cell differentiation [GO:0010742]; very-low-density lipoprotein particle assembly [GO:0034379] brush border [GO:0005903]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789] acyltransferase activity [GO:0016746]; cholesterol binding [GO:0015485]; cholesterol O-acyltransferase activity [GO:0034736]; fatty-acyl-CoA binding [GO:0000062]; sterol O-acyltransferase activity [GO:0004772] 0.95416 -1.5241 TEGLGGERER 0 0 0 0 0 0 0 0 0 0 9.25285 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75911 DHRS3_HUMAN Short-chain dehydrogenase/reductase 3 (EC 1.1.1.300) (DD83.1) (Retinal short-chain dehydrogenase/reductase 1) (retSDR1) (Retinol dehydrogenase 17) (Short chain dehydrogenase/reductase family 16C member 1) DHRS3 RDH17 SDR16C1 UNQ2424/PRO4983 Homo sapiens (Human) bone morphogenesis [GO:0060349]; cardiac septum morphogenesis [GO:0060411]; negative regulation of retinoic acid receptor signaling pathway [GO:0048387]; outflow tract morphogenesis [GO:0003151]; regulation of ossification [GO:0030278]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; roof of mouth development [GO:0060021]; visual perception [GO:0007601] endoplasmic reticulum membrane [GO:0005789]; lipid droplet [GO:0005811]; photoreceptor outer segment membrane [GO:0042622] electron transfer activity [GO:0009055]; NAD-retinol dehydrogenase activity [GO:0004745]; NADP-retinol dehydrogenase activity [GO:0052650]; nucleotide binding [GO:0000166] 0.40455 0.6997 ENVLITGGGR 0 0 0 0 0 0 0 0 0 9.72398 0 9.90554 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.45459 O75912 DGKI_HUMAN Diacylglycerol kinase iota (DAG kinase iota) (DGK-iota) (EC 2.7.1.107) DGKI Homo sapiens (Human) "diacylglycerol metabolic process [GO:0046339]; intracellular signal transduction [GO:0035556]; lipid phosphorylation [GO:0046834]; platelet activation [GO:0030168]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of synaptic transmission, glutamatergic [GO:0051966]" axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; synaptic membrane [GO:0097060]; synaptic vesicle membrane [GO:0030672] ATP binding [GO:0005524]; diacylglycerol kinase activity [GO:0004143]; metal ion binding [GO:0046872] 0.89861 -0.57715 ASKRGMEQENK 0 0 0 0 0 0 0 9.32953 0 0 13.3149 0 9.36988 9.03788 0 0 10.9282 10.865 0 0 9.9062 0 0 0 0 0 0 O75915 PRAF3_HUMAN PRA1 family protein 3 (ADP-ribosylation factor-like protein 6-interacting protein 5) (ARL-6-interacting protein 5) (Aip-5) (Cytoskeleton-related vitamin A-responsive protein) (Dermal papilla-derived protein 11) (GTRAP3-18) (Glutamate transporter EAAC1-interacting protein) (JM5) (Prenylated Rab acceptor protein 2) (Protein JWa) (Putative MAPK-activating protein PM27) ARL6IP5 DERP11 JWA PRA2 PRAF3 HSPC127 Homo sapiens (Human) cellular response to organic cyclic compound [GO:0071407]; glutathione metabolic process [GO:0006749]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; L-glutamate import across plasma membrane [GO:0098712]; L-glutamate transmembrane transport [GO:0015813]; learning or memory [GO:0007611]; negative regulation of L-glutamate import across plasma membrane [GO:0002037]; negative regulation of mitochondrial membrane potential [GO:0010917]; negative regulation of transport [GO:0051051]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein localization to plasma membrane [GO:0072659]; protein transport [GO:0015031] cytoskeleton [GO:0005856]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886]; presynaptic cytosol [GO:0099523] 0.065476 1.2919 MDVNIAPLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.86228 9.47838 9.54967 O75916 RGS9_HUMAN Regulator of G-protein signaling 9 (RGS9) RGS9 Homo sapiens (Human) dark adaptation [GO:1990603]; G protein-coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; light adaption [GO:0036367]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; visual perception [GO:0007601] cytoplasm [GO:0005737]; glutamatergic synapse [GO:0098978]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; presynaptic membrane [GO:0042734] GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924] 0.95936 -1.9179 QLEEEAKAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1933 0 0 0 0 9.86963 0 0 0 O75923 DYSF_HUMAN Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1) DYSF FER1L1 Homo sapiens (Human) macrophage activation involved in immune response [GO:0002281]; monocyte activation involved in immune response [GO:0002280]; negative regulation of phagocytosis [GO:0050765]; regulation of neurotransmitter secretion [GO:0046928] centriolar satellite [GO:0034451]; cytoplasmic vesicle membrane [GO:0030659]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; late endosome [GO:0005770]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; synaptic vesicle membrane [GO:0030672]; T-tubule [GO:0030315] calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; phospholipid binding [GO:0005543] 0.88792 -0.3995 GANYCGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4317 0 9.14652 0 9.51341 0 0 0 0 0 10.4186 0 O75936 BODG_HUMAN "Gamma-butyrobetaine dioxygenase (EC 1.14.11.1) (Gamma-butyrobetaine hydroxylase) (Gamma-BBH) (Gamma-butyrobetaine,2-oxoglutarate dioxygenase)" BBOX1 BBH BBOX Homo sapiens (Human) carnitine biosynthetic process [GO:0045329] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739] gamma-butyrobetaine dioxygenase activity [GO:0008336]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; zinc ion binding [GO:0008270] 0.91713 -0.86031 DTIFDVPVER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5001 0 0 0 0 0 0 0 0 0 0 0 O75943 RAD17_HUMAN Cell cycle checkpoint protein RAD17 (hRad17) (RF-C/activator 1 homolog) RAD17 R24L Homo sapiens (Human) DNA damage checkpoint signaling [GO:0000077]; DNA damage response [GO:0006974]; DNA repair [GO:0006281]; DNA replication checkpoint signaling [GO:0000076]; mitotic DNA replication checkpoint signaling [GO:0033314]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; negative regulation of DNA replication [GO:0008156]; regulation of phosphorylation [GO:0042325] nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Rad17 RFC-like complex [GO:0031389] ATP binding [GO:0005524]; chromatin binding [GO:0003682]; DNA clamp loader activity [GO:0003689] 0.95336 -1.4977 YRENCLAAK 0 0 0 0 0 0 0 0 0 0 0 9.69848 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75947 ATP5H_HUMAN "ATP synthase subunit d, mitochondrial (ATPase subunit d) (ATP synthase peripheral stalk subunit d)" ATP5PD ATP5H My032 Homo sapiens (Human) proton motive force-driven ATP synthesis [GO:0015986]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776] "mitochondrial inner membrane [GO:0005743]; mitochondrial proton-transporting ATP synthase complex [GO:0005753]; mitochondrial proton-transporting ATP synthase, stator stalk [GO:0000274]; mitochondrion [GO:0005739]" proton transmembrane transporter activity [GO:0015078] 0.46714 0.63204 AGLVDDFEK 0 0 0 0 0 0 8.94184 0 0 0 9.60574 0 0 0 0 0 0 0 0 0 0 0 0 0 8.56198 0 0 O75953 DNJB5_HUMAN DnaJ homolog subfamily B member 5 (Heat shock protein Hsp40-2) (Heat shock protein Hsp40-3) (Heat shock protein cognate 40) (Hsc40) DNAJB5 HSC40 Homo sapiens (Human) chaperone cofactor-dependent protein refolding [GO:0051085]; response to unfolded protein [GO:0006986] cytosol [GO:0005829] protein-folding chaperone binding [GO:0051087]; unfolded protein binding [GO:0051082] 0.95265 -1.4661 EIAEAYDVLSDPK 12.4791 0 0 0 0 0 11.8353 0 0 0 0 0 0 0 0 10.3188 0 0 0 0 0 0 0 0 0 0 0 O75954 TSN9_HUMAN Tetraspanin-9 (Tspan-9) (Tetraspan NET-5) TSPAN9 NET5 Homo sapiens (Human) focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; tetraspanin-enriched microdomain [GO:0097197] 0.96222 -2.5506 TGKKYDA 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.89312 0 0 0 0 0 0 0 0 0 0 0 O75962 TRIO_HUMAN Triple functional domain protein (EC 2.7.11.1) (PTPRF-interacting protein) TRIO Homo sapiens (Human) axon guidance [GO:0007411]; negative regulation of fat cell differentiation [GO:0045599]; neuron projection morphogenesis [GO:0048812]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein phosphorylation [GO:0006468]; regulation of small GTPase mediated signal transduction [GO:0051056]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; glutamatergic synapse [GO:0098978]; postsynapse [GO:0098794]; presynaptic active zone [GO:0048786] ATP binding [GO:0005524]; guanyl-nucleotide exchange factor activity [GO:0005085]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96871 -3.3472 APIEDLDLEGQKLLQR 0 0 0 0 0 0 0 0 10.2491 0 0 14.1411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O75964 ATP5L_HUMAN "ATP synthase subunit g, mitochondrial (ATPase subunit g) (ATP synthase membrane subunit g)" ATP5MG ATP5L Homo sapiens (Human) proton motive force-driven ATP synthesis [GO:0015986]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776] "mitochondrial inner membrane [GO:0005743]; mitochondrial proton-transporting ATP synthase complex [GO:0005753]; mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) [GO:0000276]; mitochondrion [GO:0005739]" proton transmembrane transporter activity [GO:0015078] 0.011876 1.691 IVNSAQTGSFK 0 0 0 0 0 0 0 9.30419 0 0 0 0 0 0 0 0 0 0 0 0 0 9.76469 9.79054 9.87032 0 0 9.83319 O75969 AKAP3_HUMAN A-kinase anchor protein 3 (AKAP-3) (A-kinase anchor protein 110 kDa) (AKAP 110) (Cancer/testis antigen 82) (CT82) (Fibrous sheath protein of 95 kDa) (FSP95) (Fibrousheathin I) (Fibrousheathin-1) (Protein kinase A-anchoring protein 3) (PRKA3) (Sperm oocyte-binding protein) AKAP3 AKAP110 SOB1 Homo sapiens (Human) acrosome reaction [GO:0007340]; blastocyst hatching [GO:0001835]; protein localization [GO:0008104]; single fertilization [GO:0007338]; transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178] acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; sperm fibrous sheath [GO:0035686]; sperm midpiece [GO:0097225]; sperm principal piece [GO:0097228] protein kinase A binding [GO:0051018] 0.95626 -1.5904 APGSGDRVSGSSQSPPNLK 0 0 0 0 0 0 0 0 0 9.85342 0 0 0 0 0 0 0 0 0 10.418 0 0 0 0 0 0 0 O75970 MPDZ_HUMAN Multiple PDZ domain protein (Multi-PDZ domain protein 1) MPDZ MUPP1 Homo sapiens (Human) microtubule organizing center organization [GO:0031023]; regulation of microtubule cytoskeleton organization [GO:0070507]; tight junction assembly [GO:0120192] apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; apicolateral plasma membrane [GO:0016327]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] 0.95091 -1.4204 GMGSRLSNGEVMRGIFIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.41244 0 0 0 0 0 0 0 10.3036 0 0 O75976 CBPD_HUMAN Carboxypeptidase D (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180) CPD Homo sapiens (Human) peptide metabolic process [GO:0006518]; protein processing [GO:0016485] extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886] metallocarboxypeptidase activity [GO:0004181]; serine-type carboxypeptidase activity [GO:0004185]; zinc ion binding [GO:0008270] 0.96326 -2.0895 EFETLIK 0 0 0 8.86851 0 0 0 0 0 0 0 0 0 9.83635 0 0 0 0 0 0 0 0 0 0 0 0 0 O76003 GLRX3_HUMAN Glutaredoxin-3 (PKC-interacting cousin of thioredoxin) (PICOT) (PKC-theta-interacting protein) (PKCq-interacting protein) (Thioredoxin-like protein 2) GLRX3 PICOT TXNL2 HUSSY-22 Homo sapiens (Human) [2Fe-2S] cluster assembly [GO:0044571]; cell redox homeostasis [GO:0045454]; intracellular iron ion homeostasis [GO:0006879]; iron-sulfur cluster assembly [GO:0016226]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; protein maturation by iron-sulfur cluster transfer [GO:0097428]; regulation of the force of heart contraction [GO:0002026] cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; iron-sulfur cluster assembly complex [GO:1990229]; nucleus [GO:0005634]; Z disc [GO:0030018] identical protein binding [GO:0042802]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; protein kinase C binding [GO:0005080]; RNA binding [GO:0003723] 0.95916 -1.7161 EDLNLRLK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6168 0 0 0 0 0 0 0 0 0 0 0 0 0 O76015 KRT38_HUMAN "Keratin, type I cuticular Ha8 (Hair keratin, type I Ha8) (Keratin-38) (K38)" KRT38 HHA8 HKA8 KRTHA8 Homo sapiens (Human) epithelial cell differentiation [GO:0030855]; intermediate filament organization [GO:0045109] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882] structural molecule activity [GO:0005198] 0.73083 0.33569 DCLQNSLCEAEDR 0 0 0 0 0 0 0 9.2737 9.09901 0 9.88199 0 0 0 0 9.32384 0 0 0 0 9.82944 0 0 0 0 0 0 O76021 RL1D1_HUMAN Ribosomal L1 domain-containing protein 1 (CATX-11) (Cellular senescence-inhibited gene protein) (Protein PBK1) RSL1D1 CATX11 CSIG PBK1 L12 Homo sapiens (Human) osteoblast differentiation [GO:0001649]; regulation of apoptotic process [GO:0042981]; regulation of cellular senescence [GO:2000772]; regulation of protein localization [GO:0032880] 90S preribosome [GO:0030686]; chromosome [GO:0005694]; membrane [GO:0016020]; nucleolus [GO:0005730] cadherin binding [GO:0045296]; mRNA 3'-UTR binding [GO:0003730]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723] 0.96826 -2.9203 ELRVRLTLPHSIR 0 0 0 0 9.07465 0 0 0 0 0 0 0 0 0 0 0 9.35878 0 0 9.07839 9.04327 0 0 0 0 0 0 O76024 WFS1_HUMAN Wolframin WFS1 Homo sapiens (Human) calcium ion homeostasis [GO:0055074]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; glucose homeostasis [GO:0042593]; kidney development [GO:0001822]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATF6-mediated unfolded protein response [GO:1903892]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of programmed cell death [GO:0043069]; negative regulation of response to endoplasmic reticulum stress [GO:1903573]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of translation [GO:0017148]; negative regulation of type B pancreatic cell apoptotic process [GO:2000675]; nervous system process [GO:0050877]; olfactory behavior [GO:0042048]; pancreas development [GO:0031016]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of ERAD pathway [GO:1904294]; positive regulation of growth [GO:0045927]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein ubiquitination [GO:0031398]; protein maturation by protein folding [GO:0022417]; protein stabilization [GO:0050821]; renal water homeostasis [GO:0003091]; response to endoplasmic reticulum stress [GO:0034976]; sensory perception of sound [GO:0007605]; ubiquitin-dependent ERAD pathway [GO:0030433]; visual perception [GO:0007601] dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; secretory granule [GO:0030141]; synaptic vesicle membrane [GO:0030672] ATPase binding [GO:0051117]; calcium-dependent protein binding [GO:0048306]; calmodulin binding [GO:0005516]; DNA-binding transcription factor binding [GO:0140297]; proteasome binding [GO:0070628]; translation regulator activity [GO:0045182]; ubiquitin protein ligase binding [GO:0031625] 0.96365 -2.2036 LGSKWPVFELK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.64847 0 0 0 0 0 0 0 0 0 0 0 0 O76027 ANXA9_HUMAN Annexin A9 (Annexin XXXI) (Annexin-31) (Annexin-9) (Pemphaxin) ANXA9 ANX31 Homo sapiens (Human) cell-cell adhesion [GO:0098609] cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; synapse [GO:0045202] acetylcholine receptor activity [GO:0015464]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; phosphatidylserine binding [GO:0001786]; phospholipid binding [GO:0005543] 0.9146 -0.77829 TFLNFSVDKDAQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8049 0 0 0 0 0 0 0 0 0 O76031 CLPX_HUMAN "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial" CLPX Homo sapiens (Human) ATP metabolic process [GO:0046034]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603] cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; mitochondrial endopeptidase Clp complex [GO:0009841]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; unfolded protein binding [GO:0051082]; zinc ion binding [GO:0008270] 0.89873 -0.59004 AAAAADLANR 0 11.9056 0 0 0 0 0 0 10.1235 11.8301 0 0 0 0 15.4214 0 0 0 0 0 0 0 0 0 0 0 0 O76038 SEGN_HUMAN Secretagogin SCGN SECRET Homo sapiens (Human) regulation of long-term synaptic potentiation [GO:1900271]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509] cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular region [GO:0005576]; nucleus [GO:0005634]; synapse [GO:0045202]; terminal bouton [GO:0043195]; transport vesicle membrane [GO:0030658] calcium ion binding [GO:0005509] 0.83516 0.19677 LDLNDLAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.53025 9.44919 0 0 0 0 O76039 CDKL5_HUMAN Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9) CDKL5 STK9 Homo sapiens (Human) modulation of chemical synaptic transmission [GO:0050804]; neuron migration [GO:0001764]; positive regulation of axon extension [GO:0045773]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of GTPase activity [GO:0043547]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cilium assembly [GO:1902017]; regulation of dendrite development [GO:0050773]; regulation of postsynapse organization [GO:0099175] centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary tip [GO:0097542]; dendrite cytoplasm [GO:0032839]; dendritic growth cone [GO:0044294]; glutamatergic synapse [GO:0098978]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; small GTPase binding [GO:0031267] 0.88479 -0.13002 ISDLQTQSQPLK 0 0 0 0 0 0 0 9.10528 0 0 0 0 0 9.78795 0 0 0 9.33969 0 0 0 0 0 0 0 0 0 O76041 NEBL_HUMAN Nebulette (Actin-binding Z-disk protein) NEBL C10orf113 LNEBL Homo sapiens (Human) cardiac muscle thin filament assembly [GO:0071691] extracellular exosome [GO:0070062]; I band [GO:0031674]; stress fiber [GO:0001725]; Z disc [GO:0030018] actin filament binding [GO:0051015]; cytoskeletal protein binding [GO:0008092]; filamin binding [GO:0031005]; structural constituent of muscle [GO:0008307]; tropomyosin binding [GO:0005523] 0.96962 -5.0539 GNAVLQSQVK 0 0 0 0 0 0 0 0 0 0 0 0 9.23026 9.81356 0 11.5647 0 0 0 0 0 0 0 0 0 0 12.2076 O76064 RNF8_HUMAN E3 ubiquitin-protein ligase RNF8 (hRNF8) (EC 2.3.2.27) (RING finger protein 8) (RING-type E3 ubiquitin transferase RNF8) RNF8 KIAA0646 Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; DNA damage response [GO:0006974]; DNA repair-dependent chromatin remodeling [GO:0140861]; double-strand break repair [GO:0006302]; double-strand break repair via nonhomologous end joining [GO:0006303]; epigenetic regulation of gene expression [GO:0040029]; histone H2A K63-linked ubiquitination [GO:0070535]; histone H2B ubiquitination [GO:0033523]; interstrand cross-link repair [GO:0036297]; isotype switching [GO:0045190]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; positive regulation of DNA repair [GO:0045739]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; response to ionizing radiation [GO:0010212]; signal transduction in response to DNA damage [GO:0042770]; sperm DNA condensation [GO:0035092]; ubiquitin-dependent protein catabolic process [GO:0006511] "chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]; ubiquitin ligase complex [GO:0000151]" chromatin binding [GO:0003682]; histone binding [GO:0042393]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.96157 -2.57 GEPGFFVTGDRAGGR 0 0 0 10.5826 10.4977 0 0 0 0 0 0 0 0 0 0 0 0 0 9.52121 0 0 0 10.1614 0 0 0 10.8481 O76070 SYUG_HUMAN Gamma-synuclein (Breast cancer-specific gene 1 protein) (Persyn) (Synoretin) (SR) SNCG BCSG1 PERSYN PRSN Homo sapiens (Human) adult locomotory behavior [GO:0008344]; chemical synaptic transmission [GO:0007268]; protein secretion [GO:0009306]; regulation of dopamine secretion [GO:0014059]; regulation of neuron death [GO:1901214]; regulation of neurotransmitter secretion [GO:0046928]; synapse organization [GO:0050808]; synaptic vesicle endocytosis [GO:0048488] axon terminus [GO:0043679]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471]; spindle [GO:0005819] cuprous ion binding [GO:1903136] 0.87693 -0.0001019 EGVMYVGAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.14093 0 0 0 0 0 O76074 PDE5A_HUMAN "cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (cGMP-binding cGMP-specific phosphodiesterase) (CGB-PDE)" PDE5A PDE5 Homo sapiens (Human) cGMP catabolic process [GO:0046069]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of T cell proliferation [GO:0042130]; oocyte development [GO:0048599]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of oocyte development [GO:0060282]; regulation of nitric oxide mediated signal transduction [GO:0010749]; relaxation of cardiac muscle [GO:0055119]; signal transduction [GO:0007165]; T cell proliferation [GO:0042098] cytosol [GO:0005829] "3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]" 0.92609 -1.1817 AGKIQNK 0 0 0 0 0 0 0 9.10894 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O76075 DFFB_HUMAN DNA fragmentation factor subunit beta (EC 3.-.-.-) (Caspase-activated deoxyribonuclease) (CAD) (Caspase-activated DNase) (Caspase-activated nuclease) (CPAN) (DNA fragmentation factor 40 kDa subunit) (DFF-40) DFFB CAD DFF2 DFF40 Homo sapiens (Human) apoptotic chromosome condensation [GO:0030263]; apoptotic DNA fragmentation [GO:0006309]; DNA catabolic process [GO:0006308]; negative regulation of apoptotic DNA fragmentation [GO:1902511] chromatin [GO:0000785]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA endonuclease activity [GO:0004520]; DNA nuclease activity [GO:0004536]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904] 0.9616 -2.0752 FGVAGRSCQEVLR 0 0 0 0 0 0 0 0 0 0 0 0 9.23599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O76081 RGS20_HUMAN Regulator of G-protein signaling 20 (RGS20) (Gz-selective GTPase-activating protein) (G(z)GAP) (Gz-GAP) (Regulator of G-protein signaling Z1) (Regulator of Gz-selective protein signaling 1) RGS20 RGSZ1 ZGAP1 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; regulation of G protein-coupled receptor signaling pathway [GO:0008277] cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802] GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924] 0.77244 0.27168 DLLQSLSEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4515 O76083 PDE9A_HUMAN "High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35)" PDE9A Homo sapiens (Human) cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383] "3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]" 0.81878 0.21871 GSGSSSYRPK 0 0 0 0 0 0 9.07417 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O76094 SRP72_HUMAN Signal recognition particle subunit SRP72 (SRP72) (Signal recognition particle 72 kDa protein) SRP72 Homo sapiens (Human) SRP-dependent cotranslational protein targeting to membrane [GO:0006614] "cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; signal recognition particle [GO:0048500]; signal recognition particle, endoplasmic reticulum targeting [GO:0005786]" 7S RNA binding [GO:0008312]; RNA binding [GO:0003723]; signal recognition particle binding [GO:0005047]; TPR domain binding [GO:0030911] 0.96509 -2.2877 HLPSSDSMSLK 0 16.6633 11.2309 0 0 0 16.4929 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O76100 OR7AA_HUMAN Olfactory receptor 7A10 (OST027) (Olfactory receptor OR19-18) OR7A10 Homo sapiens (Human) signal transduction [GO:0007165] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.71294 0.36703 GAMKTFFRGK 0 0 0 0 0 0 0 0 0 0 9.20114 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O94759 TRPM2_HUMAN Transient receptor potential cation channel subfamily M member 2 (Estrogen-responsive element-associated gene 1 protein) (Long transient receptor potential channel 2) (LTrpC-2) (LTrpC2) (Transient receptor potential channel 7) (TrpC7) (Transient receptor potential melastatin 2) TRPM2 EREG1 KNP3 LTRPC2 TRPC7 Homo sapiens (Human) calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to purine-containing compound [GO:0071415]; cellular response to temperature stimulus [GO:0071502]; dendritic cell chemotaxis [GO:0002407]; dendritic cell differentiation [GO:0097028]; estrous cycle [GO:0044849]; positive regulation of insulin secretion [GO:0032024]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; protein homotetramerization [GO:0051289]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of filopodium assembly [GO:0051489]; release of sequestered calcium ion into cytosol [GO:0051209]; response to heat [GO:0009408]; response to hydroperoxide [GO:0033194]; response to purine-containing compound [GO:0014074]; temperature homeostasis [GO:0001659]; zinc ion transmembrane transport [GO:0071577] cytoplasmic vesicle membrane [GO:0030659]; ficolin-1-rich granule membrane [GO:0101003]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821] calcium channel activity [GO:0005262]; calcium ion binding [GO:0005509]; calcium-release channel activity [GO:0015278]; ligand-gated calcium channel activity [GO:0099604]; manganese ion transmembrane transporter activity [GO:0005384]; mono-ADP-D-ribose binding [GO:0072571]; monoatomic cation channel activity [GO:0005261]; sodium channel activity [GO:0005272] 0.9192 -0.89913 LQDVGTPAAR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4824 0 0 0 0 0 0 0 0 0 0 0 0 0 O94760 DDAH1_HUMAN "N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (DDAH-1) (Dimethylarginine dimethylaminohydrolase 1) (EC 3.5.3.18) (DDAHI) (Dimethylargininase-1)" DDAH1 DDAH Homo sapiens (Human) arginine catabolic process [GO:0006527]; arginine metabolic process [GO:0006525]; citrulline metabolic process [GO:0000052]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular response to hypoxia [GO:1900038]; negative regulation of vascular permeability [GO:0043116]; nitric oxide mediated signal transduction [GO:0007263]; positive regulation of angiogenesis [GO:0045766]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of systemic arterial blood pressure [GO:0003073] cytosol [GO:0005829]; extracellular exosome [GO:0070062] amino acid binding [GO:0016597]; catalytic activity [GO:0003824]; dimethylargininase activity [GO:0016403]; metal ion binding [GO:0046872] 0.0099502 1.8511 AGLGHPAAFGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9794 10.9566 O94761 RECQ4_HUMAN "ATP-dependent DNA helicase Q4 (EC 3.6.4.12) (DNA helicase, RecQ-like type 4) (RecQ4) (RTS) (RecQ protein-like 4)" RECQL4 RECQ4 Homo sapiens (Human) DNA duplex unwinding [GO:0032508]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; telomere maintenance [GO:0000723]; telomeric D-loop disassembly [GO:0061820] "chromosome [GO:0005694]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]" ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; bubble DNA binding [GO:0000405]; DNA/DNA annealing activity [GO:1990814]; four-way junction helicase activity [GO:0009378]; helicase activity [GO:0004386]; oxidized purine DNA binding [GO:0032357]; telomeric D-loop binding [GO:0061821] 0.96045 -1.9934 DQICDFLYGRVQAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.95409 11.2165 0 O94762 RECQ5_HUMAN "ATP-dependent DNA helicase Q5 (EC 3.6.4.12) (DNA helicase, RecQ-like type 5) (RecQ5) (RecQ protein-like 5)" RECQL5 RECQ5 Homo sapiens (Human) cell division [GO:0051301]; cellular response to camptothecin [GO:0072757]; cellular response to ketone [GO:1901655]; cellular response to xenobiotic stimulus [GO:0071466]; chromosome separation [GO:0051304]; DNA metabolic process [GO:0006259]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; mitotic cell cycle [GO:0000278]; mitotic DNA-templated DNA replication [GO:1990506]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414] chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; replication fork [GO:0005657]; transcription preinitiation complex [GO:0097550] 3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA helicase activity [GO:0003678]; enzyme activator activity [GO:0008047]; four-way junction helicase activity [GO:0009378]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; molecular function inhibitor activity [GO:0140678]; nucleic acid binding [GO:0003676]; RNA polymerase II complex binding [GO:0000993] 0.92416 -1.0395 ANLFYDVQFK 0 0 13.1822 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.84277 11.6851 O94763 RMP_HUMAN Unconventional prefoldin RPB5 interactor 1 (Protein NNX3) (Protein phosphatase 1 regulatory subunit 19) (RNA polymerase II subunit 5-mediating protein) (RPB5-mediating protein) URI1 C19orf2 NNX3 PPP1R19 RMP URI Homo sapiens (Human) cellular response to growth factor stimulus [GO:0071363]; cellular response to steroid hormone stimulus [GO:0071383]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of phosphatase activity [GO:0010923]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein stabilization [GO:0050821]; regulation of cell growth [GO:0001558]; regulation of transcription by RNA polymerase II [GO:0006357]; response to virus [GO:0009615] cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein folding chaperone complex [GO:0101031]; RPAP3/R2TP/prefoldin-like complex [GO:1990062] chromatin binding [GO:0003682]; phosphatase inhibitor activity [GO:0019212]; phosphoprotein binding [GO:0051219]; protein phosphatase inhibitor activity [GO:0004864]; RNA polymerase II complex binding [GO:0000993]; transcription corepressor activity [GO:0003714] 0.92996 -1.245 TIDDLKKVMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.94433 0 0 0 0 0 O94766 B3GA3_HUMAN "Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 (EC 2.4.1.135) (Beta-1,3-glucuronyltransferase 3) (Glucuronosyltransferase I) (GlcAT-I) (UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase) (GlcUAT-I)" B3GAT3 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate proteoglycan biosynthetic process [GO:0050650]; dermatan sulfate proteoglycan biosynthetic process [GO:0050651]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; positive regulation of catalytic activity [GO:0043085]; positive regulation of intracellular protein transport [GO:0090316]; protein glycosylation [GO:0006486] cis-Golgi network [GO:0005801]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020] galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity [GO:0015018]; glucuronosyltransferase activity [GO:0015020]; metal ion binding [GO:0046872]; protein phosphatase activator activity [GO:0072542] 0.93141 -1.2711 LSQTLSLVPR 0 0 0 0 0 10.0038 0 0 0 9.72101 0 0 0 10.8916 0 0 0 0 0 0 0 0 0 0 0 0 0 O94768 ST17B_HUMAN Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2) STK17B DRAK2 Homo sapiens (Human) apoptotic process [GO:0006915]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fibroblast apoptotic process [GO:2000271]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468] actin cytoskeleton [GO:0015629]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; nucleus [GO:0005634]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.91331 -0.76168 ENIPEDSSMVSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2533 0 0 0 O94769 ECM2_HUMAN Extracellular matrix protein 2 (Matrix glycoprotein SC1/ECM2) ECM2 Homo sapiens (Human) cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; positive regulation of cell-substrate adhesion [GO:0010811] extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; interstitial matrix [GO:0005614] collagen V binding [GO:0070052]; heparin binding [GO:0008201]; integrin binding [GO:0005178] 0.165 0.991 GITMYNK 0 0 0 0 0 0 0 0 9.98413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O94772 LY6H_HUMAN Lymphocyte antigen 6H (Ly-6H) LY6H Homo sapiens (Human) acetylcholine receptor signaling pathway [GO:0095500]; animal organ morphogenesis [GO:0009887]; nervous system development [GO:0007399] extracellular region [GO:0005576]; plasma membrane [GO:0005886]; synapse [GO:0045202] acetylcholine receptor binding [GO:0033130]; acetylcholine receptor inhibitor activity [GO:0030550] 0.70125 0.37321 MCASSCDFVK 0 0 9.63079 0 0 0 0 0 9.6575 9.85723 9.81088 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O94776 MTA2_HUMAN Metastasis-associated protein MTA2 (Metastasis-associated 1-like 1) (MTA1-L1 protein) (p53 target protein in deacetylase complex) MTA2 MTA1L1 PID Homo sapiens (Human) chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; DNA methylation [GO:0006306]; histone deacetylation [GO:0016575]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell fate specification [GO:0042659]; regulation of fibroblast migration [GO:0010762]; regulation of stem cell differentiation [GO:2000736] "chromatin [GO:0000785]; chromosome, telomeric region [GO:0000781]; histone deacetylase complex [GO:0000118]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NuRD complex [GO:0016581]; protein-containing complex [GO:0032991]; transcription regulator complex [GO:0005667]" chromatin binding [GO:0003682]; histone deacetylase activity [GO:0004407]; histone deacetylase binding [GO:0042826]; metal ion binding [GO:0046872]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific DNA binding [GO:0043565]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714] 0.91144 -0.74867 AVGTFAR 9.69935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O94778 AQP8_HUMAN Aquaporin-8 (AQP-8) AQP8 Homo sapiens (Human) ammonium import across plasma membrane [GO:0140157]; ammonium transmembrane transport [GO:0072488]; B cell differentiation [GO:0030183]; cellular detoxification [GO:1990748]; cellular response to cAMP [GO:0071320]; hydrogen peroxide transmembrane transport [GO:0080170]; methylammonium transport [GO:0015843]; regulation of cholesterol biosynthetic process [GO:0045540]; transepithelial water transport [GO:0035377]; urea transport [GO:0015840]; water transport [GO:0006833] apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; intracellular canaliculus [GO:0046691]; intracellular vesicle [GO:0097708]; mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; smooth endoplasmic reticulum [GO:0005790]; smooth endoplasmic reticulum membrane [GO:0030868] ammonium transmembrane transporter activity [GO:0008519]; methylammonium channel activity [GO:0015264]; urea channel activity [GO:0015265]; water channel activity [GO:0015250] 0.95512 -1.5549 WRVSWYER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4129 0 0 O94779 CNTN5_HUMAN Contactin-5 (Neural recognition molecule NB-2) (hNB-2) CNTN5 Homo sapiens (Human) axon guidance [GO:0007411]; brain development [GO:0007420]; cell-cell adhesion [GO:0098609]; presynapse assembly [GO:0099054]; sensory perception of sound [GO:0007605] axon [GO:0030424]; extracellular region [GO:0005576]; GABA-ergic synapse [GO:0098982]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734] cell-cell adhesion mediator activity [GO:0098632] 0.88665 -0.35607 AENSRGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.24783 0 0 8.36741 0 0 10.3652 O94782 UBP1_HUMAN "Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.4.19.12) (Deubiquitinating enzyme 1) (hUBP) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) [Cleaved into: Ubiquitin carboxyl-terminal hydrolase 1, N-terminal fragment]" USP1 Homo sapiens (Human) DNA repair [GO:0006281]; monoubiquitinated protein deubiquitination [GO:0035520]; positive regulation of error-prone translesion synthesis [GO:1904333]; protein deubiquitination [GO:0016579]; regulation of DNA repair [GO:0006282]; response to UV [GO:0009411]; skeletal system development [GO:0001501]; ubiquitin-dependent protein catabolic process [GO:0006511] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] cysteine-type deubiquitinase activity [GO:0004843]; cysteine-type endopeptidase activity [GO:0004197]; peptidase activity [GO:0008233] 0.8841 -0.25117 GVVENYNDEEVSIR 0 0 8.90497 0 0 0 0 0 0 0 0 0 0 10.8277 10.6959 0 0 0 0 0 0 10.5638 0 9.83047 0 0 0 O94788 AL1A2_HUMAN Retinal dehydrogenase 2 (RALDH 2) (RalDH2) (EC 1.2.1.36) (Aldehyde dehydrogenase family 1 member A2) (ALDH1A2) (Retinaldehyde-specific dehydrogenase type 2) (RALDH(II)) ALDH1A2 RALDH2 Homo sapiens (Human) 9-cis-retinoic acid biosynthetic process [GO:0042904]; blood vessel development [GO:0001568]; cardiac muscle tissue development [GO:0048738]; cell population proliferation [GO:0008283]; cellular response to retinoic acid [GO:0071300]; determination of bilateral symmetry [GO:0009855]; embryonic camera-type eye development [GO:0031076]; embryonic digestive tract development [GO:0048566]; embryonic forelimb morphogenesis [GO:0035115]; face development [GO:0060324]; heart morphogenesis [GO:0003007]; hindbrain development [GO:0030902]; kidney development [GO:0001822]; liver development [GO:0001889]; lung development [GO:0030324]; midgut development [GO:0007494]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of cell population proliferation [GO:0008285]; neural crest cell development [GO:0014032]; neural tube development [GO:0021915]; neuron differentiation [GO:0030182]; pancreas development [GO:0031016]; pituitary gland development [GO:0021983]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; protein homotetramerization [GO:0051289]; proximal/distal pattern formation [GO:0009954]; regulation of vascular endothelial cell proliferation [GO:1905562]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to retinoic acid [GO:0032526]; response to vitamin A [GO:0033189]; retinal metabolic process [GO:0042574]; retinoic acid biosynthetic process [GO:0002138]; retinoic acid metabolic process [GO:0042573]; retinoic acid receptor signaling pathway involved in somitogenesis [GO:0090242]; retinol metabolic process [GO:0042572]; ureter maturation [GO:0035799]; vitamin A metabolic process [GO:0006776] cytoplasm [GO:0005737]; cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471] 3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; retinal binding [GO:0016918]; retinal dehydrogenase activity [GO:0001758] 0.4872 0.61972 IFVEESIYEEFVRR 0 0 0 0 0 0 0 0 0 0 0 0 10.638 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O94804 STK10_HUMAN Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase) STK10 LOK Homo sapiens (Human) cell cycle [GO:0007049]; lymphocyte aggregation [GO:0071593]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of lymphocyte migration [GO:2000401] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579] ATP binding [GO:0005524]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96953 -6.4561 ELVAEAK 9.72067 0 0 0 8.9458 0 9.7649 0 9.72311 9.80726 9.44363 9.44849 0 0 10.8118 8.65939 0 11.1041 0 0 0 0 0 0 12.1838 0 0 O94805 ACL6B_HUMAN Actin-like protein 6B (53 kDa BRG1-associated factor B) (Actin-related protein Baf53b) (ArpNalpha) (BRG1-associated factor 53B) (BAF53B) ACTL6B ACTL6 BAF53B Homo sapiens (Human) chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; dendrite development [GO:0016358]; histone H4 acetylation [GO:0043967]; negative regulation of cell differentiation [GO:0045596]; nervous system development [GO:0007399]; neuron maturation [GO:0042551]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of T cell differentiation [GO:0045582]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357]; spinal cord development [GO:0021510] bBAF complex [GO:0140092]; brahma complex [GO:0035060]; chromatin [GO:0000785]; GBAF complex [GO:0140288]; kinetochore [GO:0000776]; nBAF complex [GO:0071565]; NuA4 histone acetyltransferase complex [GO:0035267]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]; RSC-type complex [GO:0016586]; SWI/SNF complex [GO:0016514] chromatin binding [GO:0003682]; structural constituent of cytoskeleton [GO:0005200]; transcription coactivator activity [GO:0003713] 0.8089 0.22668 IPEGLFDPSNVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0967 0 0 0 0 O94806 KPCD3_HUMAN Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (Protein kinase EPK2) (nPKC-nu) PRKD3 EPK2 PRKCN Homo sapiens (Human) protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; protein kinase D signaling [GO:0089700]; protein phosphorylation [GO:0006468]; sphingolipid biosynthetic process [GO:0030148] cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654] ATP binding [GO:0005524]; calcium-dependent protein kinase C activity [GO:0004698]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein kinase C activity [GO:0004697]; protein serine kinase activity [GO:0106310] 0.91422 -0.82481 MFFLDPSDLDVERDEEAVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.28214 0 0 0 0 O94812 BAIP3_HUMAN BAI1-associated protein 3 (BAP3) (Brain-specific angiogenesis inhibitor I-associated protein 3) BAIAP3 KIAA0734 Homo sapiens (Human) "dense core granule maturation [GO:1990502]; exocytosis [GO:0006887]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of neurotransmitter secretion [GO:0001956]; regulation of dense core granule exocytosis [GO:1905413]; regulation of synaptic transmission, GABAergic [GO:0032228]; retrograde transport, endosome to Golgi [GO:0042147]" cytosol [GO:0005829]; late endosome membrane [GO:0031902]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; recycling endosome membrane [GO:0055038]; secretory vesicle [GO:0099503]; trans-Golgi network membrane [GO:0032588] calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905] 0.84938 0.16516 LEHSAEEPNSSSWR 0 0 0 0 0 8.87289 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O94813 SLIT2_HUMAN Slit homolog 2 protein (Slit-2) [Cleaved into: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product] SLIT2 SLIL3 Homo sapiens (Human) aortic valve morphogenesis [GO:0003180]; apoptotic process involved in luteolysis [GO:0061364]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; branching morphogenesis of an epithelial tube [GO:0048754]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to heparin [GO:0071504]; cellular response to hormone stimulus [GO:0032870]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; corticospinal neuron axon guidance through spinal cord [GO:0021972]; induction of negative chemotaxis [GO:0050929]; motor neuron axon guidance [GO:0008045]; negative chemotaxis [GO:0050919]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular response to growth factor stimulus [GO:0090288]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of lamellipodium assembly [GO:0010593]; negative regulation of leukocyte chemotaxis [GO:0002689]; negative regulation of monocyte chemotaxis [GO:0090027]; negative regulation of mononuclear cell migration [GO:0071676]; negative regulation of neutrophil chemotaxis [GO:0090024]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of retinal ganglion cell axon guidance [GO:0090260]; negative regulation of small GTPase mediated signal transduction [GO:0051058]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of vascular permeability [GO:0043116]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; pulmonary valve morphogenesis [GO:0003184]; response to cortisol [GO:0051414]; retinal ganglion cell axon guidance [GO:0031290]; Roundabout signaling pathway [GO:0035385]; ureteric bud development [GO:0001657]; ventricular septum morphogenesis [GO:0060412] cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020] calcium ion binding [GO:0005509]; GTPase inhibitor activity [GO:0005095]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; laminin-1 binding [GO:0043237]; protein homodimerization activity [GO:0042803]; proteoglycan binding [GO:0043394]; Roundabout binding [GO:0048495] 0.95069 -1.401 CPTECTCLDTVVRCSNK 9.51722 9.75487 0 0 0 9.09511 10.7865 11.0313 11.0503 0 0 9.81216 9.84123 0 10.3656 0 0 0 0 10.0318 0 0 0 0 0 0 0 O94817 ATG12_HUMAN Ubiquitin-like protein ATG12 (Autophagy-related protein 12) (APG12-like) ATG12 APG12 APG12L Homo sapiens (Human) autophagosome assembly [GO:0000045]; autophagy of mitochondrion [GO:0000422]; autophagy of nucleus [GO:0044804]; C-terminal protein lipidation [GO:0006501]; macroautophagy [GO:0016236]; negative regulation of defense response to virus [GO:0050687]; negative regulation of innate immune response [GO:0045824]; negative regulation of type I interferon production [GO:0032480]; positive regulation of viral translation [GO:1904973]; protein lipidation [GO:0006497]; regulation of autophagosome maturation [GO:1901096] Atg12-Atg5-Atg16 complex [GO:0034274]; autophagosome [GO:0005776]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; phagocytic vesicle membrane [GO:0030670]; phagophore assembly site membrane [GO:0034045]; protein-containing complex [GO:0032991]; transferase complex [GO:1990234] 0.87704 -0.0083292 AVGDTPIMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.30665 0 0 0 0 0 0 O94818 NOL4_HUMAN Nucleolar protein 4 (Nucleolar-localized protein) NOL4 NOLP HRIHFB2255 Homo sapiens (Human) nucleolus [GO:0005730] RNA binding [GO:0003723] 0.91901 -0.8981 GGGGGAK 9.18373 0 0 0 0 0 0 9.46777 0 9.24467 9.36076 0 8.77264 0 0 0 0 0 0 7.84587 0 0 0 0 0 0 0 O94822 LTN1_HUMAN E3 ubiquitin-protein ligase listerin (EC 2.3.2.27) (RING finger protein 160) (RING-type E3 ubiquitin transferase listerin) (Zinc finger protein 294) LTN1 C21orf10 C21orf98 KIAA0714 RNF160 ZNF294 HSPC087 Homo sapiens (Human) protein autoubiquitination [GO:0051865]; rescue of stalled ribosome [GO:0072344]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] cytosol [GO:0005829]; RQC complex [GO:1990112] ribosomal large subunit binding [GO:0043023]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.80915 0.23176 ACPSSDK 0 0 0 0 0 0 0 9.82372 0 0 10.2574 8.77076 0 0 10.109 0 0 0 0 0 9.16962 9.68403 0 0 0 0 9.90808 O94823 AT10B_HUMAN Phospholipid-transporting ATPase VB (EC 7.6.2.1) (ATPase class V type 10B) (P4-ATPase flippase complex alpha subunit ATP10B) ATP10B ATPVB KIAA0715 Homo sapiens (Human) lysosomal membrane organization [GO:0097212]; phospholipid translocation [GO:0045332] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; phospholipid-translocating ATPase complex [GO:1990531]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled intramembrane lipid transporter activity [GO:0140326]; glycosylceramide flippase activity [GO:0140351]; magnesium ion binding [GO:0000287]; phosphatidylcholine flippase activity [GO:0140345] 0.8413 0.18192 AINCSNIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5175 0 0 0 0 0 0 0 0 0 0 0 O94826 TOM70_HUMAN Mitochondrial import receptor subunit TOM70 (Mitochondrial precursor proteins import receptor) (Translocase of outer membrane 70 kDa subunit) (Translocase of outer mitochondrial membrane protein 70) TOMM70 KIAA0719 TOM70 TOMM70A Homo sapiens (Human) activation of innate immune response [GO:0002218]; cellular response to virus [GO:0098586]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of protein import [GO:1904591]; protein import into mitochondrial matrix [GO:0030150]; protein insertion into mitochondrial inner membrane [GO:0045039]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein targeting to mitochondrion [GO:0006626]; regulation of apoptotic process [GO:0042981]; response to thyroxine [GO:0097068] extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial membrane [GO:0031966]; mitochondrial outer membrane [GO:0005741]; mitochondrial outer membrane translocase complex [GO:0005742]; mitochondrion [GO:0005739] mitochondrion targeting sequence binding [GO:0030943]; molecular adaptor activity [GO:0060090]; molecular function activator activity [GO:0140677]; protein transmembrane transporter activity [GO:0008320] 0.89859 -0.64417 AAAFEQLQK 0 0 0 0 0 0 0 0 0 9.87557 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O94827 PKHG5_HUMAN Pleckstrin homology domain-containing family G member 5 (PH domain-containing family G member 5) (Guanine nucleotide exchange factor 720) (GEF720) PLEKHG5 KIAA0720 Homo sapiens (Human) endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266] axon [GO:0030424]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle [GO:0030139]; lamellipodium [GO:0030027]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] guanyl-nucleotide exchange factor activity [GO:0005085] 0.96954 -4.5865 ELIDGHEK 0 0 0 9.74593 0 0 8.53103 0 0 0 0 0 0 0 9.78599 0 0 0 0 0 9.38446 0 0 0 0 0 0 O94830 DDHD2_HUMAN "Phospholipase DDHD2 (EC 3.1.1.-) (DDHD domain-containing protein 2) (KIAA0725p) (SAM, WWE and DDHD domain-containing protein 1)" DDHD2 KIAA0725 SAMWD1 Homo sapiens (Human) lipid droplet organization [GO:0034389]; locomotory behavior [GO:0007626]; mitochondrial fission [GO:0000266]; positive regulation of mitochondrial fission [GO:0090141]; triglyceride catabolic process [GO:0019433]; visual learning [GO:0008542] centriolar satellite [GO:0034451]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytosol [GO:0005829]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; membrane [GO:0016020] metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806] 0.96214 -2.5512 EGLTRMSMDLK 9.87822 0 0 0 0 0 0 0 0 0 0 0 8.17283 0 0 0 8.94559 11.7259 9.01184 0 8.09233 0 0 10.0126 0 0 0 O94832 MYO1D_HUMAN Unconventional myosin-Id MYO1D KIAA0727 Homo sapiens (Human) actin filament organization [GO:0007015]; cellular localization [GO:0051641]; early endosome to recycling endosome transport [GO:0061502]; protein transport [GO:0015031]; vesicle transport along actin filament [GO:0030050] actin cytoskeleton [GO:0015629]; apical dendrite [GO:0097440]; axolemma [GO:0030673]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; brush border [GO:0005903]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; myelin sheath [GO:0043209]; myosin complex [GO:0016459]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; smooth endoplasmic reticulum [GO:0005790]; vesicle [GO:0031982] actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calmodulin binding [GO:0005516]; microfilament motor activity [GO:0000146]; protein domain specific binding [GO:0019904] 0.92647 -1.2078 AEQESLEFGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.2243 0 0 0 0 0 0 0 0 0 0 0 0 O94844 RHBT1_HUMAN Rho-related BTB domain-containing protein 1 RHOBTB1 KIAA0740 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; Cdc42 protein signal transduction [GO:0032488]; endocytosis [GO:0006897]; establishment or maintenance of cell polarity [GO:0007163] endosome membrane [GO:0010008] GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.92423 -1.0686 DVFDNAIR 0 0 0 0 0 0 0 10.9748 0 9.61235 10.9385 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O94850 DEND_HUMAN Dendrin DDN KIAA0749 Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944] cell projection [GO:0042995]; cytoplasm [GO:0005737]; dendritic spine membrane [GO:0032591]; endoplasmic reticulum membrane [GO:0005789]; nucleus [GO:0005634]; perikaryon [GO:0043204]; postsynaptic membrane [GO:0045211] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.92525 -0.98426 LDGPLFSEGPDSPR 0 14.7573 14.6873 0 0 0 14.6058 0 0 0 0 14.1111 0 11.5179 0 12.2694 12.1285 11.8822 0 0 0 10.5142 0 0 0 0 0 O94851 MICA2_HUMAN [F-actin]-monooxygenase MICAL2 (EC 1.14.13.225) (MICAL C-terminal-like protein) (Mical-cL) (Molecule interacting with CasL protein 2) (MICAL-2) MICAL2 KIAA0750 MICAL2PV1 MICAL2PV2 MICALCL Homo sapiens (Human) actin filament depolymerization [GO:0030042]; cytoskeleton organization [GO:0007010]; heart development [GO:0007507]; heart looping [GO:0001947]; positive regulation of transcription by RNA polymerase II [GO:0045944]; sulfur oxidation [GO:0019417] actin filament [GO:0005884]; cytoplasm [GO:0005737]; nucleus [GO:0005634] "actin binding [GO:0003779]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]; mitogen-activated protein kinase binding [GO:0051019]; monooxygenase activity [GO:0004497]; NAD(P)H oxidase H2O2-forming activity [GO:0016174]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]" 0.84902 0.11037 ANSFQSPTPSKYQNWR 12.085 11.4005 11.1716 0 8.53134 0 11.113 11.1434 12.1432 12.064 11.4621 11.4805 8.90147 8.98593 13.8549 9.76391 14.3201 9.61706 0 0 11.7188 0 0 0 0 0 0 O94854 K0754_HUMAN "Microtubule-actin cross-linking factor 1, isoforms 6/7 (Uncharacterized protein KIAA0754)" MACF1 KIAA0754 Homo sapiens (Human) cytoplasm [GO:0005737]; cytoskeleton [GO:0005856] calcium ion binding [GO:0005509]; microtubule binding [GO:0008017] 0.47925 0.62375 DKWDTVCGK 0 0 9.46387 0 0 0 0 12.784 0 0 0 0 0 0 0 0 0 0 9.4942 0 0 0 0 8.7493 0 0 0 O94856 NFASC_HUMAN Neurofascin NFASC KIAA0756 Homo sapiens (Human) axon guidance [GO:0007411]; brain development [GO:0007420]; cell-cell adhesion [GO:0098609]; myelination [GO:0042552]; peripheral nervous system development [GO:0007422]; protein localization to plasma membrane [GO:0072659] axon [GO:0030424]; axon initial segment [GO:0043194]; dendrite [GO:0030425]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; node of Ranvier [GO:0033268]; paranodal junction [GO:0033010]; plasma membrane [GO:0005886]; Schwann cell microvillus [GO:0097454] cell-cell adhesion mediator activity [GO:0098632]; protein domain specific binding [GO:0019904] 0.92308 -1.0622 AAPTEVKVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.18388 0 0 0 0 O94868 FCSD2_HUMAN F-BAR and double SH3 domains protein 2 (Carom) (Protein nervous wreck 1) (NWK1) (SH3 multiple domains protein 3) FCHSD2 KIAA0769 SH3MD3 Homo sapiens (Human) clathrin-dependent endocytosis [GO:0072583]; membrane organization [GO:0061024]; neuromuscular synaptic transmission [GO:0007274]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; protein transport [GO:0015031]; regulation of actin filament polymerization [GO:0030833] anchoring junction [GO:0070161]; clathrin-coated pit [GO:0005905]; neuromuscular junction [GO:0031594]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; stereocilium shaft [GO:0120043] "phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]" 0.92424 -1.0131 ADDRNDYRSMYPVWK 0 0 0 0 0 11.7708 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.69167 O94874 UFL1_HUMAN E3 UFM1-protein ligase 1 (EC 2.3.2.-) (E3 UFM1-protein transferase 1) (Multiple alpha-helix protein located at ER) (Novel LZAP-binding protein) (Regulator of C53/LZAP and DDRGK1) UFL1 KIAA0776 MAXER NLBP RCAD Homo sapiens (Human) DNA damage checkpoint signaling [GO:0000077]; DNA repair [GO:0006281]; erythrocyte differentiation [GO:0030218]; hematopoietic stem cell differentiation [GO:0060218]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein ubiquitination [GO:0031397]; osteoblast differentiation [GO:0001649]; positive regulation of autophagy [GO:0010508]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of glial cell proliferation [GO:0060252]; protein K69-linked ufmylation [GO:1990592]; protein ufmylation [GO:0071569]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; regulation of protein localization [GO:0032880]; response to endoplasmic reticulum stress [GO:0034976]; response to L-glutamate [GO:1902065]; reticulophagy [GO:0061709] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861] protein kinase binding [GO:0019901]; UFM1 ligase activity [GO:0061666]; UFM1 transferase activity [GO:0071568] 0.8972 -0.53319 AQFAEATQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.67483 8.9443 8.50327 0 0 9.00377 0 0 0 9.24374 O94875 SRBS2_HUMAN Sorbin and SH3 domain-containing protein 2 (Arg-binding protein 2) (ArgBP2) (Arg/Abl-interacting protein 2) (Sorbin) SORBS2 ARGBP2 KIAA0777 Homo sapiens (Human) cell growth involved in cardiac muscle cell development [GO:0061049]; Notch signaling pathway [GO:0007219] actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; dendrite [GO:0030425]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]; Z disc [GO:0030018] cytoskeletal anchor activity [GO:0008093]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307] 0.95866 -1.6922 HDWDPPDRK 0 0 0 0 0 0 0 0 0 0 0 0 9.66951 0 0 0 0 0 0 0 0 9.53339 0 0 0 10.4186 0 O94880 PHF14_HUMAN PHD finger protein 14 PHF14 KIAA0783 Homo sapiens (Human) germinal center B cell differentiation [GO:0002314]; lung alveolus development [GO:0048286]; mesenchymal cell proliferation [GO:0010463]; mesenchymal cell proliferation involved in lung development [GO:0060916]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of mesenchymal cell proliferation [GO:0072201]; negative regulation of mesenchymal cell proliferation involved in lung development [GO:2000791]; negative regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000584]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; nucleus [GO:0005634] histone binding [GO:0042393]; histone reader activity [GO:0140566]; zinc ion binding [GO:0008270] 0.96578 -2.7221 DKLENEQEKLHVEYNK 0 0 0 0 0 0 0 0 0 0 0 0 10.9286 0 16.7686 0 0 0 0 0 0 0 0 0 0 0 0 O94885 SASH1_HUMAN SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat-containing protein) SASH1 KIAA0790 PEPE1 Homo sapiens (Human) positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of p38MAPK cascade [GO:1900745]; protein polyubiquitination [GO:0000209]; regulation of epithelial cell migration [GO:0010632]; regulation of protein autoubiquitination [GO:1902498]; regulation of protein K63-linked ubiquitination [GO:1900044] cytoplasm [GO:0005737]; protein-containing complex [GO:0032991] G-protein alpha-subunit binding [GO:0001965]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; molecular adaptor activity [GO:0060090]; protein kinase binding [GO:0019901] 0.96243 -2.5382 CGIPEALVQR 0 0 0 0 0 0 0 0 0 0 0 9.11187 0 0 0 0 0 0 0 0 9.08775 0 0 0 0 0 0 O94886 CSCL1_HUMAN CSC1-like protein 1 (Transmembrane protein 63A) TMEM63A KIAA0489 KIAA0792 Homo sapiens (Human) centriolar satellite [GO:0034451]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821] calcium activated cation channel activity [GO:0005227]; mechanosensitive monoatomic ion channel activity [GO:0008381]; nucleic acid binding [GO:0003676]; osmolarity-sensing monoatomic cation channel activity [GO:1990760] 0.87696 -0.0002213 LLERITEEER 0 0 0 0 0 0 0 0 9.25642 9.58352 9.74651 9.50377 0 0 0 0 0 0 0 10.3017 10.3579 0 0 0 0 0 0 O94887 FARP2_HUMAN "FERM, ARHGEF and pleckstrin domain-containing protein 2 (FERM domain-including RhoGEF) (FIR) (FERM, RhoGEF and pleckstrin domain-containing protein 2) (Pleckstrin homology domain-containing family C member 3) (PH domain-containing family C member 3)" FARP2 KIAA0793 PLEKHC3 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; cell adhesion [GO:0007155]; hair cycle process [GO:0022405]; neuron remodeling [GO:0016322]; osteoclast differentiation [GO:0030316]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; regulation of integrin activation [GO:0033623]; semaphorin-plexin signaling pathway [GO:0071526] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829] cytoskeletal protein binding [GO:0008092]; guanyl-nucleotide exchange factor activity [GO:0005085] 0.96312 -2.1873 AVFFSRGSSFRYSGR 0 0 9.86731 0 0 0 0 9.89916 9.55515 0 0 0 0 0 0 0 0 0 0 11.1642 0 9.49025 0 0 0 0 9.45917 O94889 KLH18_HUMAN Kelch-like protein 18 KLHL18 KIAA0795 OK/SW-cl.74 Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; positive regulation of mitotic cell cycle phase transition [GO:1901992]; protein ubiquitination [GO:0016567] 0.89894 -0.6861 RQGKLCDVTLK 0 0 0 0 0 0 0 0 0 0 12.2688 0 0 9.43471 0 0 0 0 0 0 0 0 0 0 0 0 0 O94898 LRIG2_HUMAN Leucine-rich repeats and immunoglobulin-like domains protein 2 (LIG-2) LRIG2 KIAA0806 LIG2 Homo sapiens (Human) innervation [GO:0060384]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of axon regeneration [GO:0048681]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; positive regulation of protein localization to cell surface [GO:2000010]; protein localization to cell surface [GO:0034394]; regulation of neuron migration [GO:2001222]; regulation of platelet-derived growth factor receptor signaling pathway [GO:0010640]; sensory perception of sound [GO:0007605] cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; growth cone [GO:0030426]; intracellular vesicle [GO:0097708]; plasma membrane [GO:0005886] signaling receptor binding [GO:0005102] 0.56235 0.50776 IVEGLTFQGLDSLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.82537 8.97968 0 0 0 0 O94901 SUN1_HUMAN SUN domain-containing protein 1 (Protein unc-84 homolog A) (Sad1/unc-84 protein-like 1) SUN1 KIAA0810 UNC84A Homo sapiens (Human) centrosome localization [GO:0051642]; homologous chromosome pairing at meiosis [GO:0007129]; meiotic attachment of telomere to nuclear envelope [GO:0070197]; nuclear matrix anchoring at nuclear membrane [GO:0090292]; nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration [GO:0021817]; spermatogenesis [GO:0007283] "chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; meiotic nuclear membrane microtubule tethering complex [GO:0034993]; nuclear envelope [GO:0005635]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]" cytoskeleton-nuclear membrane anchor activity [GO:0140444]; lamin binding [GO:0005521]; protein-membrane adaptor activity [GO:0043495] 0.91432 -0.81711 ELEQTKQK 0 0 10.2345 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.06369 0 0 9.46029 0 11.1369 9.88513 0 0 0 O94903 PLPHP_HUMAN Pyridoxal phosphate homeostasis protein (PLP homeostasis protein) (Proline synthase co-transcribed bacterial homolog protein) (Pyridoxal phosphate-binding protein) PLPBP PROSC Homo sapiens (Human) cytoplasm [GO:0005737]; cytosol [GO:0005829] pyridoxal phosphate binding [GO:0030170] 0.89896 -0.65877 IGSTIFGER 0 0 9.37812 0 0 0 0 0 0 0 0 0 0 11.698 0 0 0 0 0 0 0 0 0 9.65625 0 0 0 O94905 ERLN2_HUMAN Erlin-2 (Endoplasmic reticulum lipid raft-associated protein 2) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2) (SPFH domain-containing protein 2) ERLIN2 C8orf2 SPFH2 UNQ2441/PRO5003/PRO9924 Homo sapiens (Human) cholesterol metabolic process [GO:0008203]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of fatty acid biosynthetic process [GO:0045717]; regulation of cholesterol biosynthetic process [GO:0045540]; SREBP signaling pathway [GO:0032933]; ubiquitin-dependent ERAD pathway [GO:0030433] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] cholesterol binding [GO:0015485]; ubiquitin protein ligase binding [GO:0031625] 0.16367 0.98379 AIASNSK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3512 12.2062 0 0 0 0 0 0 0 0 0 0 0 0 O94906 PRP6_HUMAN Pre-mRNA-processing factor 6 (Androgen receptor N-terminal domain-transactivating protein 1) (ANT-1) (PRP6 homolog) (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein) PRPF6 C20orf14 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; RNA localization [GO:0006403]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal complex assembly [GO:0000245]; spliceosomal tri-snRNP complex assembly [GO:0000244]" catalytic step 2 spliceosome [GO:0071013]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682] identical protein binding [GO:0042802]; ribonucleoprotein complex binding [GO:0043021]; RNA binding [GO:0003723] 0.9696 -4.6708 AAELETDIR 0 0 0 0 0 0 0 0 0 9.5786 8.75265 0 0 0 0 0 0 0 11.2981 0 11.1833 10.6188 10.5989 10.478 11.6608 11.6465 11.6578 O94907 DKK1_HUMAN Dickkopf-related protein 1 (Dickkopf-1) (Dkk-1) (hDkk-1) (SK) DKK1 UNQ492/PRO1008 Homo sapiens (Human) "canonical Wnt signaling pathway [GO:0060070]; cell morphogenesis involved in differentiation [GO:0000904]; embryonic limb morphogenesis [GO:0030326]; endocardial cushion development [GO:0003197]; endoderm formation [GO:0001706]; face morphogenesis [GO:0060325]; forebrain development [GO:0030900]; hair follicle development [GO:0001942]; heart valve development [GO:0003170]; learning or memory [GO:0007611]; limb development [GO:0060173]; mesoderm formation [GO:0001707]; motor learning [GO:0061743]; negative regulation of apoptotic process [GO:0043066]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment [GO:1901296]; negative regulation of cardiac muscle cell differentiation [GO:2000726]; negative regulation of mesodermal cell fate specification [GO:0042662]; negative regulation of neuron projection development [GO:0010977]; negative regulation of ossification [GO:0030279]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of presynapse assembly [GO:1905607]; negative regulation of protein binding [GO:0032091]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of Wnt signaling pathway [GO:0030178]; negative regulation of Wnt-Frizzled-LRP5/6 complex assembly [GO:1904723]; positive regulation of gene expression [GO:0010628]; positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway [GO:0090082]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of midbrain dopaminergic neuron differentiation [GO:1904958]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of Wnt signaling pathway, calcium modulating pathway [GO:0045813]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; regulation of dopaminergic neuron differentiation [GO:1904338]; regulation of endodermal cell fate specification [GO:0042663]; regulation of neuron apoptotic process [GO:0043523]; regulation of receptor internalization [GO:0002090]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to retinoic acid [GO:0032526]; synapse pruning [GO:0098883]; Wnt signaling pathway involved in somitogenesis [GO:0090244]" early endosome membrane [GO:0031901]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] co-receptor binding [GO:0039706]; growth factor activity [GO:0008083]; low-density lipoprotein particle receptor binding [GO:0050750]; receptor antagonist activity [GO:0048019] 0.96257 -2.1674 CMRHAMCCPGNYCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.45 O94910 AGRL1_HUMAN Adhesion G protein-coupled receptor L1 (Calcium-independent alpha-latrotoxin receptor 1) (CIRL-1) (Latrophilin-1) (Lectomedin-2) ADGRL1 KIAA0821 LEC2 LPHN1 Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; positive regulation of synapse maturation [GO:0090129] axon [GO:0030424]; growth cone [GO:0030426]; membrane [GO:0016020]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynaptic membrane [GO:0042734]; synapse [GO:0045202] carbohydrate binding [GO:0030246]; cell adhesion molecule binding [GO:0050839]; G protein-coupled receptor activity [GO:0004930]; latrotoxin receptor activity [GO:0016524] 0.96465 -2.4302 DPLQAGDR 0 0 9.61884 0 0 0 0 0 0 0 0 10.9247 8.68064 9.32146 0 11.9058 9.83928 0 9.68809 0 0 0 8.5622 0 0 0 0 O94911 ABCA8_HUMAN ABC-type organic anion transporter ABCA8 (EC 7.6.2.-) (ATP-binding cassette sub-family A member 8) ABCA8 KIAA0822 Homo sapiens (Human) cholesterol efflux [GO:0033344]; cholesterol transport [GO:0030301]; lipid transport [GO:0006869]; positive regulation of cholesterol efflux [GO:0010875]; regulation of cholesterol efflux [GO:0010874]; sphingomyelin biosynthetic process [GO:0006686]; transmembrane transport [GO:0055085]; xenobiotic transport [GO:0042908] basolateral plasma membrane [GO:0016323]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886] ABC-type transporter activity [GO:0140359]; ABC-type xenobiotic transporter activity [GO:0008559]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]; lipid transporter activity [GO:0005319] 0.96674 -2.3245 CLEWKFGK 10.4285 0 0 0 0 0 0 0 0 11.2372 0 0 0 11.4192 0 0 0 0 0 0 0 0 0 10.5097 0 0 0 O94913 PCF11_HUMAN Pre-mRNA cleavage complex 2 protein Pcf11 (Pre-mRNA cleavage complex II protein Pcf11) PCF11 KIAA0824 Homo sapiens (Human) mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378]; termination of RNA polymerase II transcription [GO:0006369] cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; mRNA cleavage factor complex [GO:0005849]; nucleoplasm [GO:0005654] mRNA binding [GO:0003729]; RNA polymerase II complex binding [GO:0000993] 0.97005 -4.2967 APHQVPVQSEK 0 0 0 0 0 0 0 0 0 0 0 0 12.3856 0 0 0 11.2537 0 10.7196 8.86375 9.59548 9.80735 0 0 0 0 0 O94915 FRYL_HUMAN Protein furry homolog-like (ALL1-fused gene from chromosome 4p12 protein) FRYL AF4P12 KIAA0826 Homo sapiens (Human) cell morphogenesis [GO:0000902]; neuron projection development [GO:0031175] cell cortex [GO:0005938]; site of polarized growth [GO:0030427] 0.96773 -2.9667 INHSSSLAR 0 12.2468 12.1624 0 0 0 11.2878 0 11.4419 12.353 14.2734 0 0 0 0 0 0 0 0 9.21868 0 0 0 0 0 11.7927 0 O94916 NFAT5_HUMAN Nuclear factor of activated T-cells 5 (NF-AT5) (T-cell transcription factor NFAT5) (Tonicity-responsive enhancer-binding protein) (TonE-binding protein) (TonEBP) NFAT5 KIAA0827 TONEBP Homo sapiens (Human) calcineurin-NFAT signaling cascade [GO:0033173]; cellular hyperosmotic response [GO:0071474]; cellular response to cytokine stimulus [GO:0071345]; DNA damage response [GO:0006974]; positive regulation of gene expression [GO:0010628]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R-loop processing [GO:0062176]; regulation of calcineurin-NFAT signaling cascade [GO:0070884]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transcription by RNA polymerase II [GO:0006366] chromatin [GO:0000785]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.92316 -1.0785 SLHSCSVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2671 0 0 0 0 0 0 0 0 0 10.5388 O94919 ENDD1_HUMAN Endonuclease domain-containing 1 protein (EC 3.1.30.-) ENDOD1 KIAA0830 Homo sapiens (Human) innate immune response [GO:0045087] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020] endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676] 0.82928 0.20925 VTFDNSGEL 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1988 0 0 0 0 0 0 0 0 0 0 O94921 CDK14_HUMAN Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) (Serine/threonine-protein kinase PFTAIRE-1) (hPFTAIRE1) CDK14 KIAA0834 PFTK1 Homo sapiens (Human) cell division [GO:0051301]; G2/M transition of mitotic cell cycle [GO:0000086]; protein phosphorylation [GO:0006468]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; Wnt signaling pathway [GO:0016055] cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytoplasmic cyclin-dependent protein kinase holoenzyme complex [GO:0000308]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein serine kinase activity [GO:0106310] 0.95969 -1.9233 LGEGSYATVYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.30813 0 0 0 0 0 O94923 GLCE_HUMAN D-glucuronyl C5-epimerase (EC 5.1.3.17) (Heparan sulfate C5-epimerase) (Hsepi) (Heparin/heparan sulfate:glucuronic acid C5-epimerase) (Heparosan-N-sulfate-glucuronate 5-epimerase) GLCE KIAA0836 Homo sapiens (Human) heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparin biosynthetic process [GO:0030210] Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139] "calcium ion binding [GO:0005509]; heparosan-N-sulfate-glucuronate 5-epimerase activity [GO:0047464]; protein homodimerization activity [GO:0042803]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]" 0.9677 -2.7512 EARSLYERGMESLK 0 0 0 0 0 0 0 0 0 0 0 0 0 8.90716 0 0 0 0 0 0 0 9.79142 0 0 0 0 0 O94925 GLSK_HUMAN "Glutaminase kidney isoform, mitochondrial (GLS) (EC 3.5.1.2) (K-glutaminase) (L-glutamine amidohydrolase) [Cleaved into: Glutaminase kidney isoform, mitochondrial 68 kDa chain; Glutaminase kidney isoform, mitochondrial 65 kDa chain]" GLS GLS1 KIAA0838 Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; glutamate biosynthetic process [GO:0006537]; glutamine catabolic process [GO:0006543]; intracellular glutamate homeostasis [GO:0090461]; protein homotetramerization [GO:0051289]; regulation of respiratory gaseous exchange by nervous system process [GO:0002087]; suckling behavior [GO:0001967] cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; synapse [GO:0045202] glutaminase activity [GO:0004359] 0.92377 -1.0117 RAQPLVTLCRRPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.18611 0 0 0 10.3517 0 O94927 HAUS5_HUMAN HAUS augmin-like complex subunit 5 HAUS5 KIAA0841 Homo sapiens (Human) cell division [GO:0051301]; centrosome cycle [GO:0007098]; spindle assembly [GO:0051225] centrosome [GO:0005813]; cytosol [GO:0005829]; HAUS complex [GO:0070652]; mitotic spindle microtubule [GO:1990498] 0.88052 0.01445 TVGVLVSQR 0 0 0 0 0 0 0 0 0 0 0 0 11.3349 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O94929 ABLM3_HUMAN Actin-binding LIM protein 3 (abLIM-3) (Actin-binding LIM protein family member 3) ABLIM3 KIAA0843 HMFN1661 Homo sapiens (Human) cilium assembly [GO:0060271]; cytoskeleton organization [GO:0007010]; lamellipodium assembly [GO:0030032]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of transcription by RNA polymerase II [GO:0045944]; transcription by RNA polymerase II [GO:0006366] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; glutamatergic synapse [GO:0098978]; lamellipodium [GO:0030027]; stress fiber [GO:0001725] actin filament binding [GO:0051015]; metal ion binding [GO:0046872] 0.91399 -0.79612 RFSSGGEEDDFDR 0 0 0 0 0 10.668 0 0 0 0 0 0 9.33865 0 0 0 0 10.8454 0 0 0 0 0 0 0 0 0 O94933 SLIK3_HUMAN SLIT and NTRK-like protein 3 SLITRK3 KIAA0848 Homo sapiens (Human) "axonogenesis [GO:0007409]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; neurotransmitter-gated ion channel clustering [GO:0072578]; positive regulation of synapse assembly [GO:0051965]; regulation of presynapse assembly [GO:1905606]; synaptic membrane adhesion [GO:0099560]; synaptic transmission, GABAergic [GO:0051932]; terminal button organization [GO:0072553]" cell surface [GO:0009986]; GABA-ergic synapse [GO:0098982]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic specialization membrane [GO:0099634] 0.93162 -1.261 ENHSNYRTLLEK 0 0 0 0 0 9.67677 0 0 10.8691 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O94941 RNF37_HUMAN RING finger protein 37 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RNF37) (U-box domain-containing protein 5) (UbcM4-interacting protein 5) (hUIP5) (Ubiquitin-conjugating enzyme 7-interacting protein 5) UBOX5 KIAA0860 RNF37 UBCE7IP5 UIP5 Homo sapiens (Human) protein polyubiquitination [GO:0000209] focal adhesion [GO:0005925]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] metal ion binding [GO:0046872]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-ubiquitin ligase activity [GO:0034450] 0.76343 0.2969 EPVYQLPCGHLLCRPCLGEK 0 0 0 0 0 9.06377 0 0 0 0 0 0 0 0 0 0 10.4277 0 0 0 0 0 0 0 0 0 0 O94956 SO2B1_HUMAN Solute carrier organic anion transporter family member 2B1 (Organic anion transporter B) (OATP-B) (Organic anion transporter polypeptide-related protein 2) (OATP-RP2) (OATPRP2) (Organic anion transporting polypeptide 2B1) (OATP2B1) (Solute carrier family 21 member 9) SLCO2B1 KIAA0880 OATP2B1 OATPB SLC21A9 Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; heme catabolic process [GO:0042167]; monoatomic ion transport [GO:0006811]; organic anion transport [GO:0015711]; sodium-independent organic anion transport [GO:0043252]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; xenobiotic metabolic process [GO:0006805] apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; plasma membrane [GO:0005886] bile acid transmembrane transporter activity [GO:0015125]; organic anion transmembrane transporter activity [GO:0008514]; prostaglandin transmembrane transporter activity [GO:0015132]; sodium-independent organic anion transmembrane transporter activity [GO:0015347]; transmembrane transporter activity [GO:0022857] 0.92412 -1.0042 IGPAGEVPQVPDKETKATMGTENTPGGK 0 0 0 0 0 9.07756 0 0 0 0 0 0 0 0 0 0 0 10.2983 0 0 0 0 0 10.0588 0 0 0 O94964 SOGA1_HUMAN "Protein SOGA1 (SOGA family member 1) (Suppressor of glucose by autophagy) (Suppressor of glucose, autophagy-associated protein 1) [Cleaved into: N-terminal form; C-terminal 80 kDa form (80-kDa SOGA fragment)]" SOGA1 C20orf117 KIAA0889 SOGA Homo sapiens (Human) insulin receptor signaling pathway [GO:0008286]; negative regulation of gluconeogenesis [GO:0045721]; regulation of autophagy [GO:0010506] extracellular exosome [GO:0070062]; extracellular space [GO:0005615] 0.89841 -0.63448 EAEVLPGLREQAALVSK 9.50948 0 9.52804 0 0 0 0 0 0 0 0 0 10.2716 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O94967 WDR47_HUMAN WD repeat-containing protein 47 (Neuronal enriched MAP-interacting protein) (Nemitin) WDR47 KIAA0893 Homo sapiens (Human) adult locomotory behavior [GO:0008344]; anterior commissure morphogenesis [GO:0021960]; autophagy [GO:0006914]; cerebral cortex radial glia-guided migration [GO:0021801]; corpus callosum development [GO:0022038]; detection of hot stimulus involved in thermoception [GO:0120168]; microtubule cytoskeleton organization [GO:0000226]; motor behavior [GO:0061744]; negative regulation of microtubule depolymerization [GO:0007026]; neural precursor cell proliferation [GO:0061351]; neuronal stem cell population maintenance [GO:0097150] cytoplasm [GO:0005737]; dendrite [GO:0030425]; growth cone [GO:0030426]; microtubule [GO:0005874]; neuronal cell body [GO:0043025] 0.96413 -2.3907 KLSEAGFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0503 0 0 0 0 0 O94979 SC31A_HUMAN Protein transport protein Sec31A (ABP125) (ABP130) (SEC31-like protein 1) (SEC31-related protein A) (Web1-like protein) SEC31A KIAA0905 SEC31L1 HSPC275 HSPC334 Homo sapiens (Human) COPII-coated vesicle cargo loading [GO:0090110]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; response to calcium ion [GO:0051592] COPII vesicle coat [GO:0030127]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; intracellular membrane-bounded organelle [GO:0043231]; perinuclear region of cytoplasm [GO:0048471]; vesicle coat [GO:0030120] calcium-dependent protein binding [GO:0048306]; structural molecule activity [GO:0005198] 0.83494 0.18742 KNEPIIKVSDHSNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.71177 0 0 0 0 0 0 0 0 0 10.6242 0 0 O94983 CMTA2_HUMAN Calmodulin-binding transcription activator 2 CAMTA2 KIAA0909 Homo sapiens (Human) cardiac muscle hypertrophy in response to stress [GO:0014898]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; histone deacetylase binding [GO:0042826]; sequence-specific DNA binding [GO:0043565]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712] 0.91732 -0.85172 KDGYLWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3504 0 0 O94985 CSTN1_HUMAN Calsyntenin-1 (Alcadein-alpha) (Alc-alpha) (Alzheimer-related cadherin-like protein) (Non-classical cadherin XB31alpha) [Cleaved into: Soluble Alc-alpha (SAlc-alpha); CTF1-alpha (C-terminal fragment 1-alpha)] CLSTN1 CS1 KIAA0911 Homo sapiens (Human) cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurotransmitter receptor transport to postsynaptic membrane [GO:0098969]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission [GO:0050806]; regulation of cell growth [GO:0001558]; regulation of synapse maturation [GO:0090128]; vesicle-mediated transport in synapse [GO:0099003] cell surface [GO:0009986]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; neuron projection [GO:0043005]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; postsynaptic endosome [GO:0098845]; postsynaptic membrane [GO:0045211] amyloid-beta binding [GO:0001540]; calcium ion binding [GO:0005509]; kinesin binding [GO:0019894]; X11-like protein binding [GO:0042988] 0.94621 -1.3443 EKLDCELQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.22533 0 0 0 0 0 0 O94986 CE152_HUMAN Centrosomal protein of 152 kDa (Cep152) CEP152 KIAA0912 Homo sapiens (Human) cell projection organization [GO:0030030]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; de novo centriole assembly involved in multi-ciliated epithelial cell differentiation [GO:0098535] centriole [GO:0005814]; centrosome [GO:0005813]; cytosol [GO:0005829]; deuterosome [GO:0098536]; nucleoplasm [GO:0005654]; pericentriolar material [GO:0000242]; procentriole [GO:0120098]; procentriole replication complex [GO:0120099] protein kinase binding [GO:0019901] 0.96946 -6.0327 EIQLEAQIK 11.5559 11.3138 10.8078 9.97083 0 9.92035 11.6268 0 10.9569 10.784 10.6813 10.7575 0 12.1768 11.4296 0 9.77243 10.1045 11.2586 10.8812 9.93777 10.7722 9.50066 0 10.5756 0 10.0411 O94988 FA13A_HUMAN Protein FAM13A FAM13A FAM13A1 KIAA0914 Homo sapiens (Human) regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] cytosol [GO:0005829] GTPase activator activity [GO:0005096] 0.96717 -2.3171 AESSRPEDIKDMTK 0 0 11.4052 0 0 0 0 10.7502 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O94989 ARHGF_HUMAN Rho guanine nucleotide exchange factor 15 (Ephexin-5) (E5) (Vsm-RhoGEF) ARHGEF15 KIAA0915 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; negative regulation of synapse maturation [GO:2000297]; positive regulation of stress fiber assembly [GO:0051496]; regulation of catalytic activity [GO:0050790]; regulation of postsynapse assembly [GO:0150052]; regulation of small GTPase mediated signal transduction [GO:0051056]; retina vasculature morphogenesis in camera-type eye [GO:0061299] cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; postsynapse [GO:0098794] GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085] 0.95494 -1.6084 ALPLVSWSR 0 0 0 11.0819 0 0 0 10.4037 0 0 0 0 0 0 0 0 0 0 0 0 0 9.71918 10.7257 0 0 9.55182 0 O94991 SLIK5_HUMAN SLIT and NTRK-like protein 5 (Leucine-rich repeat-containing protein 11) SLITRK5 KIAA0918 LRRC11 Homo sapiens (Human) adult behavior [GO:0030534]; axonogenesis [GO:0007409]; chemical synaptic transmission [GO:0007268]; circulatory system development [GO:0072359]; dendrite morphogenesis [GO:0048813]; grooming behavior [GO:0007625]; positive regulation of synapse assembly [GO:0051965]; regulation of presynapse assembly [GO:1905606]; response to xenobiotic stimulus [GO:0009410]; skin development [GO:0043588]; striatum development [GO:0021756] plasma membrane [GO:0005886]; receptor complex [GO:0043235]; synapse [GO:0045202] 0.59149 0.44982 LHGRDLDEVSK 15.6537 15.7624 15.4348 10.4571 12.2942 12.1329 14.6309 15.0838 15.4139 14.5148 14.2956 14.3217 11.9787 14.0888 14.1084 14.0357 13.9826 11.4626 0 0 8.66558 0 0 0 0 0 9.85123 O95007 OR6B1_HUMAN Olfactory receptor 6B1 (Olfactory receptor 7-3) (OR7-3) (Olfactory receptor OR7-9) OR6B1 Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of smell [GO:0050911] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.93996 -1.3177 EALKKLAYCQASR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.7264 0 0 0 0 0 0 0 0 0 0 0 0 O95025 SEM3D_HUMAN Semaphorin-3D SEMA3D UNQ760/PRO1491 Homo sapiens (Human) negative chemotaxis [GO:0050919]; negative regulation of axon extension involved in axon guidance [GO:0048843]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; positive regulation of cell migration [GO:0030335]; semaphorin-plexin signaling pathway [GO:0071526] extracellular region [GO:0005576] chemorepellent activity [GO:0045499]; semaphorin receptor binding [GO:0030215] 0.69395 0.38345 VGRVCKNDVGGQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.80826 0 O95047 OR2A4_HUMAN Olfactory receptor 2A4 (Olfactory receptor 2A10) (Olfactory receptor OR6-37) OR2A4 OR2A10 Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of smell [GO:0050911]; positive regulation of cytokinesis [GO:0032467]; regulation of actin cytoskeleton organization [GO:0032956] cleavage furrow [GO:0032154]; Flemming body [GO:0090543]; mitotic spindle midzone [GO:1990023]; mitotic spindle pole [GO:0097431]; recycling endosome [GO:0055037] G protein-coupled receptor activity [GO:0004930]; odorant binding [GO:0005549]; olfactory receptor activity [GO:0004984] 0.92363 -1.0468 EVQRKAFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1317 0 0 0 0 0 0 0 O95067 CCNB2_HUMAN G2/mitotic-specific cyclin-B2 CCNB2 Homo sapiens (Human) cell division [GO:0051301]; G2/MI transition of meiotic cell cycle [GO:0008315]; in utero embryonic development [GO:0001701]; mitotic cell cycle phase transition [GO:0044772]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of growth [GO:0040008]; spindle assembly involved in female meiosis I [GO:0007057]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538] centrosome [GO:0005813]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; nucleus [GO:0005634] cadherin binding [GO:0045296]; cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538] 0.87684 -0.0061793 DLASPLIGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.35614 0 0 0 0 O95070 YIF1A_HUMAN Protein YIF1A (54TMp) (YIP1-interacting factor homolog A) YIF1A 54TM HYIF1P YIF1 Homo sapiens (Human) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein transport [GO:0015031] COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231] 0.87191 0.035141 YFFAVDTAYVAK 0 0 0 0 0 0 0 8.86372 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95071 UBR5_HUMAN "E3 ubiquitin-protein ligase UBR5 (EC 2.3.2.26) (E3 ubiquitin-protein ligase, HECT domain-containing 1) (HECT-type E3 ubiquitin transferase UBR5) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein)" UBR5 EDD EDD1 HYD KIAA0896 Homo sapiens (Human) DNA damage response [GO:0006974]; DNA repair [GO:0006281]; DNA repair-dependent chromatin remodeling [GO:0140861]; heterochromatin boundary formation [GO:0033696]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of protein import into nucleus [GO:0042307]; progesterone receptor signaling pathway [GO:0050847]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; regulation of double-strand break repair [GO:2000779] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991] RNA binding [GO:0003723]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-ubiquitin ligase activity [GO:0034450]; zinc ion binding [GO:0008270] 0.88316 -0.31328 AGSSSSR 0 0 0 0 0 8.8421 0 0 0 9.70789 0 0 0 0 10.8958 0 0 0 0 0 0 0 0 0 0 0 0 O95072 REC8_HUMAN Meiotic recombination protein REC8 homolog (Cohesin Rec8p) REC8 REC8L1 Homo sapiens (Human) double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; fertilization [GO:0009566]; male meiosis I [GO:0007141]; meiotic cell cycle [GO:0051321]; meiotic sister chromatid cohesion [GO:0051177]; oocyte maturation [GO:0001556]; reciprocal meiotic recombination [GO:0007131]; seminiferous tubule development [GO:0072520]; sister chromatid cohesion [GO:0007062]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130] cohesin complex [GO:0008278]; kinetochore [GO:0000776]; lateral element [GO:0000800]; male germ cell nucleus [GO:0001673]; meiotic cohesin complex [GO:0030893]; nucleus [GO:0005634] chromatin binding [GO:0003682] 0.89769 -0.55227 ELPEEAAAEEER 0 0 0 0 0 0 0 0 0 0 0 10.4192 0 0 0 0 0 0 0 0 0 0 0 0 11.5029 0 0 O95076 ALX3_HUMAN Homeobox protein aristaless-like 3 (Proline-rich transcription factor ALX3) ALX3 Homo sapiens (Human) embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic skeletal system morphogenesis [GO:0048704]; pattern specification process [GO:0007389]; regulation of apoptotic process [GO:0042981]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.8714 0.062449 TTFSTFQLEELEK 0 11.4325 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95084 PRS23_HUMAN Serine protease 23 (EC 3.4.21.-) (Putative secreted protein Zsig13) PRSS23 ZSIG13 UNQ270/PRO307 Homo sapiens (Human) proteolysis [GO:0006508] endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; nucleus [GO:0005634] serine-type endopeptidase activity [GO:0004252] 0.89853 -0.60411 GTPLPTYEEAK 9.61695 0 0 0 0 0 9.52138 0 0 0 0 0 0 0 0 0 0 9.8935 0 0 0 0 0 0 0 9.95595 0 O95104 SCAF4_HUMAN "SR-related and CTD-associated factor 4 (CTD-binding SR-like protein RA4) (Splicing factor, arginine/serine-rich 15)" SCAF4 KIAA1172 SFRS15 Homo sapiens (Human) "mRNA processing [GO:0006397]; negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled [GO:2000805]" nucleoplasm [GO:0005654]; nucleus [GO:0005634] RNA binding [GO:0003723]; RNA polymerase II C-terminal domain phosphoserine binding [GO:1990269] 0.9695 -4.8803 QSRHQFGTDK 0 0 10.8309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.29531 9.37639 0 0 0 0 O95125 ZN202_HUMAN Zinc finger protein 202 (Zinc finger protein with KRAB and SCAN domains 10) ZNF202 ZKSCAN10 Homo sapiens (Human) lipid metabolic process [GO:0006629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleolus [GO:0005730] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.95414 -1.5162 GYHLIRHQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.46442 0 0 0 0 0 O95140 MFN2_HUMAN Mitofusin-2 (EC 3.6.5.-) (Transmembrane GTPase MFN2) MFN2 CPRP1 KIAA0214 Homo sapiens (Human) apoptotic process [GO:0006915]; blastocyst formation [GO:0001825]; camera-type eye morphogenesis [GO:0048593]; mitochondrial fusion [GO:0008053]; mitochondrial membrane organization [GO:0007006]; mitochondrion localization [GO:0051646]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of smooth muscle cell proliferation [GO:0048662]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; protein localization to phagophore assembly site [GO:0034497]; protein targeting to mitochondrion [GO:0006626]; response to unfolded protein [GO:0006986] cytosol [GO:0005829]; microtubule cytoskeleton [GO:0015630]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ubiquitin protein ligase binding [GO:0031625] 0.93352 -1.2823 AFKRQFVEHASEK 9.65471 0 0 0 0 0 0 0 0 10.0021 0 0 0 0 0 0 0 0 0 10.1025 0 0 0 0 0 0 0 O95149 SPN1_HUMAN Snurportin-1 (RNA U transporter 1) SNUPN RNUT1 SPN1 Homo sapiens (Human) protein import into nucleus [GO:0006606]; RNA import into nucleus [GO:0006404]; snRNA import into nucleus [GO:0061015] cytosol [GO:0005829]; NLS-dependent protein nuclear import complex [GO:0042564]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] nuclear import signal receptor activity [GO:0061608]; RNA cap binding [GO:0000339] 0.91373 -0.76016 LDYVNHARR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.84188 0 0 0 0 O95153 RIMB1_HUMAN Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIMS-binding protein 1) (RIM-BP1) (TSPO-associated protein 1) TSPOAP1 BZRAP1 KIAA0612 RBP1 RIMBP1 Homo sapiens (Human) calyx of Held [GO:0044305]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; mitochondrion [GO:0005739] benzodiazepine receptor binding [GO:0030156]; voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels [GO:0099626] 0.94898 -1.3743 EGPQWLHVRDFDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.28824 10.3755 0 9.93404 0 0 0 0 0 O95155 UBE4B_HUMAN Ubiquitin conjugation factor E4 B (EC 2.3.2.27) (Homozygously deleted in neuroblastoma 1) (RING-type E3 ubiquitin transferase E4 B) (Ubiquitin fusion degradation protein 2) UBE4B HDNB1 KIAA0684 UFD2 Homo sapiens (Human) granzyme-mediated apoptotic signaling pathway [GO:0008626]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; response to UV [GO:0009411]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151] enzyme binding [GO:0019899]; ubiquitin-ubiquitin ligase activity [GO:0034450] 0.88448 -0.2099 AEIDYSDAPDEFR 0 0 0 0 0 0 0 9.89685 0 10.3018 9.75487 0 0 0 0 0 0 13.9147 0 0 0 0 0 0 0 10.6468 0 O95168 NDUB4_HUMAN NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (Complex I-B15) (CI-B15) (NADH-ubiquinone oxidoreductase B15 subunit) NDUFB4 Homo sapiens (Human) "aerobic respiration [GO:0009060]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]; response to oxidative stress [GO:0006979]" mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex I [GO:0005747]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] NADH dehydrogenase (ubiquinone) activity [GO:0008137] 0.86332 0.081341 TINVYPNFRPTPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1704 0 0 O95170 CDRT1_HUMAN F-box and WD repeat domain containing protein 10B (CMT1A duplicated region transcript 1 protein) FBXW10B C17orf1 C17orf1A CDRT1 HREP Homo sapiens (Human) 0.93346 -1.2835 DLSSGFSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2467 O95171 SCEL_HUMAN Sciellin SCEL Homo sapiens (Human) embryo development ending in birth or egg hatching [GO:0009792]; epidermis development [GO:0008544]; keratinocyte differentiation [GO:0030216]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; response to mechanical stimulus [GO:0009612] cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471] metal ion binding [GO:0046872] 0.96272 -2.4468 ISDRNDAAK 11.8502 11.9215 11.7159 0 0 0 12.0338 12.0799 12.2364 12.2354 11.9894 0 8.95324 0 0 0 0 0 0 0 0 8.40229 0 0 0 0 0 O95180 CAC1H_HUMAN Voltage-dependent T-type calcium channel subunit alpha-1H (Low-voltage-activated calcium channel alpha1 3.2 subunit) (Voltage-gated calcium channel subunit alpha Cav3.2) CACNA1H Homo sapiens (Human) aldosterone biosynthetic process [GO:0032342]; calcium ion import [GO:0070509]; calcium ion import across plasma membrane [GO:0098703]; cellular response to hormone stimulus [GO:0032870]; cellular response to potassium ion [GO:0035865]; cortisol biosynthetic process [GO:0034651]; inorganic cation transmembrane transport [GO:0098662]; muscle contraction [GO:0006936]; muscle organ development [GO:0007517]; myoblast fusion [GO:0007520]; positive regulation of acrosome reaction [GO:2000344]; regulation of heart contraction [GO:0008016]; regulation of membrane potential [GO:0042391]; regulation of monoatomic ion transmembrane transport [GO:0034765] membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891] high voltage-gated calcium channel activity [GO:0008331]; low voltage-gated calcium channel activity [GO:0008332]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; voltage-gated monoatomic ion channel activity [GO:0005244] 0.96917 -3.9893 EAWALYLFSPQNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7447 0 0 0 11.8601 0 O95185 UNC5C_HUMAN Netrin receptor UNC5C (Protein unc-5 homolog 3) (Protein unc-5 homolog C) UNC5C UNC5H3 Homo sapiens (Human) anterior/posterior axon guidance [GO:0033564]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; brain development [GO:0007420]; chemorepulsion of axon [GO:0061643]; dorsal root ganglion development [GO:1990791]; ectopic germ cell programmed cell death [GO:0035234]; positive regulation of apoptotic process [GO:0043065]; positive regulation of developmental process [GO:0051094]; positive regulation of reproductive process [GO:2000243]; regulation of neuron migration [GO:2001222] cell surface [GO:0009986]; dendrite [GO:0030425]; filopodium [GO:0030175]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; synapse [GO:0045202] netrin receptor activity [GO:0005042]; netrin receptor activity involved in chemorepulsion [GO:0005043]; protein kinase binding [GO:0019901]; tubulin binding [GO:0015631] 0.2894 0.8246 KTFEQEPLGK 0 0 0 0 8.75439 0 0 0 0 0 0 8.68745 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95190 OAZ2_HUMAN Ornithine decarboxylase antizyme 2 (AZ2) (ODC-Az 2) OAZ2 Homo sapiens (Human) negative regulation of polyamine transmembrane transport [GO:1902268]; polyamine biosynthetic process [GO:0006596]; polyamine metabolic process [GO:0006595]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of protein catabolic process [GO:0045732] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] ornithine decarboxylase inhibitor activity [GO:0008073] 0.80356 0.23782 VNYVFICFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.3761 0 O95196 CSPG5_HUMAN Chondroitin sulfate proteoglycan 5 (Acidic leucine-rich EGF-like domain-containing brain protein) (Neuroglycan C) CSPG5 CALEB NGC Homo sapiens (Human) axon regeneration [GO:0031103]; cell projection morphogenesis [GO:0048858]; cytoskeleton organization [GO:0007010]; glial cell projection elongation [GO:0106091]; intracellular transport [GO:0046907]; nervous system development [GO:0007399]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of synaptic vesicle exocytosis [GO:2000300] cell surface [GO:0009986]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; Golgi-associated vesicle membrane [GO:0030660]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202] growth factor activity [GO:0008083] 0.82555 0.2122 LSPASELPK 0 0 0 0 0 0 0 0 0 0 0 0 0 8.78663 0 0 0 0 0 0 0 0 0 0 0 0 0 O95197 RTN3_HUMAN Reticulon-3 (Homolog of ASY protein) (HAP) (Neuroendocrine-specific protein-like 2) (NSP-like protein 2) (Neuroendocrine-specific protein-like II) (NSP-like protein II) (NSPLII) RTN3 ASYIP NSPL2 Homo sapiens (Human) apoptotic process [GO:0006915]; brain development [GO:0007420]; endoplasmic reticulum tubular network formation [GO:0071787]; endoplasmic reticulum tubular network organization [GO:0071786]; negative regulation of amyloid-beta formation [GO:1902430]; neuron differentiation [GO:0030182]; vesicle-mediated transport [GO:0016192] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] 0.96934 -6.2405 ELGERQVEK 0 10.7405 0 0 0 0 9.28121 0 0 0 12.2538 0 0 0 0 0 0 0 0 0 0 0 10.4756 0 0 0 0 O95202 LETM1_HUMAN Mitochondrial proton/calcium exchanger protein (Electroneutral mitochondrial K(+)/H(+)exchanger) (KHE) (Leucine zipper-EF-hand-containing transmembrane protein 1) LETM1 Homo sapiens (Human) calcium export from the mitochondrion [GO:0099093]; cristae formation [GO:0042407]; inner mitochondrial membrane organization [GO:0007007]; intracellular monoatomic cation homeostasis [GO:0030003]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transmembrane transport [GO:0006851]; mitochondrial potassium ion transmembrane transport [GO:0140141]; negative regulation of mitochondrial calcium ion concentration [GO:0051562]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; regulation of cellular hyperosmotic salinity response [GO:1900069] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] calcium ion binding [GO:0005509]; calcium:proton antiporter activity [GO:0015369]; ribosome binding [GO:0043022] 0.92216 -1.1448 GMRALGVTEDRLR 10.351 10.4386 0 0 0 0 0 0 10.4861 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.98385 0 0 O95206 PCDH8_HUMAN Protocadherin-8 (Arcadlin) PCDH8 Homo sapiens (Human) cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; chemical synaptic transmission [GO:0007268]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; modulation of chemical synaptic transmission [GO:0050804]; morphogenesis of embryonic epithelium [GO:0016331]; regulation of synaptic membrane adhesion [GO:0099179]; somitogenesis [GO:0001756] dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; Schaffer collateral - CA1 synapse [GO:0098685] calcium ion binding [GO:0005509] 0.96174 -2.4546 AATCKVIVR 0 0 10.6419 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95218 ZRAB2_HUMAN "Zinc finger Ran-binding domain-containing protein 2 (Zinc finger protein 265) (Zinc finger, splicing)" ZRANB2 ZIS ZNF265 Homo sapiens (Human) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] nucleoplasm [GO:0005654] lipopolysaccharide binding [GO:0001530]; metal ion binding [GO:0046872]; RNA binding [GO:0003723] 0.96969 -4.0825 EESDGEYDEFGR 13.0645 0 0 0 0 0 0 0 0 0 8.70663 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2167 0 9.78887 O95219 SNX4_HUMAN Sorting nexin-4 SNX4 Homo sapiens (Human) endocytic recycling [GO:0032456]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of histamine secretion by mast cell [GO:1903595]; protein transport [GO:0015031] cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; membrane [GO:0016020]; plasma membrane [GO:0005886]; presynaptic endosome [GO:0098830]; protein-containing complex [GO:0032991]; SNARE complex [GO:0031201] epidermal growth factor receptor binding [GO:0005154]; insulin receptor binding [GO:0005158]; leptin receptor binding [GO:1990460]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-3-phosphate binding [GO:0032266]; transferrin receptor binding [GO:1990459] 0.96569 -2.2961 LYGVYKVHGNYGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.62394 0 0 0 0 0 0 0 0 0 O95229 ZWINT_HUMAN ZW10 interactor (ZW10-interacting protein 1) (Zwint-1) ZWINT Homo sapiens (Human) cell division [GO:0051301]; establishment of localization in cell [GO:0051649]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint signaling [GO:0007094] cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; kinetochore [GO:0000776]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654] 0.94623 -1.3444 AIAAKEQWK 0 0 8.55213 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95232 LC7L3_HUMAN Luc7-like protein 3 (Cisplatin resistance-associated-overexpressed protein) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18) (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) LUC7L3 CREAP1 CROP O48 Homo sapiens (Human) mRNA splice site selection [GO:0006376]; RNA splicing [GO:0008380] nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U1 snRNP [GO:0005685]; U2-type prespliceosome [GO:0071004] DNA binding [GO:0003677]; mRNA binding [GO:0003729]; RNA binding [GO:0003723] 0.9659 -2.3018 EKQEREER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.8983 0 0 0 0 0 0 O95235 KI20A_HUMAN Kinesin-like protein KIF20A (GG10_2) (Mitotic kinesin-like protein 2) (MKlp2) (Rab6-interacting kinesin-like protein) (Rabkinesin-6) KIF20A MKLP2 RAB6KIFL Homo sapiens (Human) microtubule bundle formation [GO:0001578]; microtubule-based movement [GO:0007018]; midbody abscission [GO:0061952]; mitotic cytokinesis [GO:0000281]; protein transport [GO:0015031]; regulation of cytokinesis [GO:0032465] Golgi apparatus [GO:0005794]; intercellular bridge [GO:0045171]; kinesin complex [GO:0005871]; microtubule [GO:0005874]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777]; protein kinase binding [GO:0019901] 0.55952 0.52086 EQWCSEHLDTQK 0 0 0 0 9.39088 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95239 KIF4A_HUMAN Chromosome-associated kinesin KIF4A (Chromokinesin-A) KIF4A KIF4 Homo sapiens (Human) anterograde axonal transport [GO:0008089]; mitotic cytokinesis [GO:0000281]; mitotic spindle midzone assembly [GO:0051256]; mitotic spindle organization [GO:0007052]; organelle organization [GO:0006996]; spindle elongation [GO:0051231] axon cytoplasm [GO:1904115]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; microtubule associated complex [GO:0005875]; midbody [GO:0030496]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; spindle microtubule [GO:0005876] ATP binding [GO:0005524]; DNA binding [GO:0003677]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777] 0.96354 -2.2 LNQEIRMMKNQR 0 0 0 0 0 0 9.22084 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4884 0 0 0 0 O95248 MTMR5_HUMAN Myotubularin-related protein 5 (Inactive phosphatidylinositol 3-phosphatase 5) (SET-binding factor 1) (Sbf1) SBF1 MTMR5 Homo sapiens (Human) protein dephosphorylation [GO:0006470]; spermatid development [GO:0007286] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; nuclear body [GO:0016604]; perinuclear region of cytoplasm [GO:0048471] guanyl-nucleotide exchange factor activity [GO:0005085]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138] 0.96957 -3.4455 AFFDVKTTRR 0 0 0 9.44014 0 0 0 10.5109 8.1644 11.8669 11.7616 8.40922 0 9.1289 0 0 10.4052 0 0 0 0 0 0 0 10.8433 0 0 O95249 GOSR1_HUMAN Golgi SNAP receptor complex member 1 (28 kDa Golgi SNARE protein) (28 kDa cis-Golgi SNARE p28) (GOS-28) GOSR1 GS28 Homo sapiens (Human) "endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle fusion [GO:0006906]" cis-Golgi network [GO:0005801]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi medial cisterna [GO:0005797]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; SNARE complex [GO:0031201]; transport vesicle [GO:0030133] SNAP receptor activity [GO:0005484] 0.95432 -1.5189 EHDHLRNSDR 0 0 0 0 0 0 0 0 0 0 0 9.98328 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95255 MRP6_HUMAN ATP-binding cassette sub-family C member 6 (EC 7.6.2.-) (EC 7.6.2.3) (Anthracycline resistance-associated protein) (Multi-specific organic anion transporter E) (MOAT-E) (Multidrug resistance-associated protein 6) ABCC6 ARA MRP6 Homo sapiens (Human) ATP metabolic process [GO:0046034]; ATP transport [GO:0015867]; calcium ion homeostasis [GO:0055074]; gene expression [GO:0010467]; inhibition of non-skeletal tissue mineralization [GO:0140928]; inorganic diphosphate transport [GO:0030505]; intracellular phosphate ion homeostasis [GO:0030643]; leukotriene transport [GO:0071716]; phosphate ion homeostasis [GO:0055062]; response to magnesium ion [GO:0032026]; response to sodium phosphate [GO:1904383]; response to xenobiotic stimulus [GO:0009410]; transmembrane transport [GO:0055085]; visual perception [GO:0007601] basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] ABC-type glutathione S-conjugate transporter activity [GO:0015431]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled inorganic anion transmembrane transporter activity [GO:0043225]; ATPase-coupled transmembrane transporter activity [GO:0042626] 0.21649 0.88563 AGWPAGK 0 0 0 0 0 0 0 0 0 0 0 9.92807 0 10.0304 0 0 0 0 0 0 0 0 9.40542 0 0 0 0 O95259 KCNH1_HUMAN Potassium voltage-gated channel subfamily H member 1 (Ether-a-go-go potassium channel 1) (EAG channel 1) (h-eag) (hEAG1) (Voltage-gated potassium channel subunit Kv10.1) KCNH1 EAG EAG1 Homo sapiens (Human) cellular response to calcium ion [GO:0071277]; myoblast fusion [GO:0007520]; phosphatidylinositol-mediated signaling [GO:0048015]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of cell population proliferation [GO:0042127]; regulation of membrane potential [GO:0042391]; regulation of monoatomic ion transmembrane transport [GO:0034765]; startle response [GO:0001964] axolemma [GO:0030673]; cell surface [GO:0009986]; dendrite [GO:0030425]; early endosome membrane [GO:0031901]; intracellular membrane-bounded organelle [GO:0043231]; nuclear inner membrane [GO:0005637]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; presynaptic membrane [GO:0042734]; voltage-gated potassium channel complex [GO:0008076] 14-3-3 protein binding [GO:0071889]; calmodulin binding [GO:0005516]; delayed rectifier potassium channel activity [GO:0005251]; identical protein binding [GO:0042802]; phosphatidylinositol bisphosphate binding [GO:1902936]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; transmembrane transporter binding [GO:0044325] 0.92193 -1.1285 ADICVHLNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0329 O95260 ATE1_HUMAN Arginyl-tRNA--protein transferase 1 (Arginyltransferase 1) (R-transferase 1) (EC 2.3.2.8) (Arginine-tRNA--protein transferase 1) ATE1 Homo sapiens (Human) proteasomal protein catabolic process [GO:0010498]; protein arginylation [GO:0016598] cytoplasm [GO:0005737]; nucleus [GO:0005634] arginyltransferase activity [GO:0004057] 0.88505 -0.38027 AKSNQPK 0 0 15.0275 0 0 0 14.0865 14.2349 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95263 PDE8B_HUMAN "High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (HsPDE8B) (EC 3.1.4.53) (Cell proliferation-inducing gene 22 protein)" PDE8B PIG22 Homo sapiens (Human) behavioral fear response [GO:0001662]; cAMP catabolic process [GO:0006198]; negative regulation of steroid hormone biosynthetic process [GO:0090032]; neuromuscular process controlling balance [GO:0050885]; operant conditioning [GO:0035106]; signal transduction [GO:0007165]; visual learning [GO:0008542] cytosol [GO:0005829] "3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]" 0.90728 -0.73802 HFEHVNK 0 0 0 0 0 0 0 0 0 10.4474 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95267 GRP1_HUMAN RAS guanyl-releasing protein 1 (Calcium and DAG-regulated guanine nucleotide exchange factor II) (CalDAG-GEFII) (Ras guanyl-releasing protein) RASGRP1 RASGRP Homo sapiens (Human) activation of GTPase activity [GO:0090630]; B cell activation [GO:0042113]; B cell proliferation [GO:0042100]; cell differentiation [GO:0030154]; inflammatory response to antigenic stimulus [GO:0002437]; mast cell degranulation [GO:0043303]; natural killer cell activation [GO:0030101]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of GTPase activity [GO:0043547]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type II interferon production [GO:0032729]; Ras protein signal transduction [GO:0007265]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; secretory granule localization [GO:0032252]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell proliferation [GO:0042098]; vesicle transport along microtubule [GO:0047496] cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; diacylglycerol binding [GO:0019992]; guanyl-nucleotide exchange factor activity [GO:0005085]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; phosphatidylcholine binding [GO:0031210]; zinc ion binding [GO:0008270] 0.9618 -2.5842 DLVVFECKKR 0 13.6512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.1529 0 0 0 0 0 O95271 TNKS1_HUMAN Poly [ADP-ribose] polymerase tankyrase-1 (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 5) (ARTD5) (Poly [ADP-ribose] polymerase 5A) (Protein poly-ADP-ribosyltransferase tankyrase-1) (EC 2.4.2.-) (TNKS-1) (TRF1-interacting ankyrin-related ADP-ribose polymerase) (Tankyrase I) (Tankyrase-1) (TANK1) TNKS PARP5A PARPL TIN1 TINF1 TNKS1 Homo sapiens (Human) "cell division [GO:0051301]; mitotic spindle organization [GO:0007052]; mRNA transport [GO:0051028]; negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric [GO:1904908]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of telomeric DNA binding [GO:1904743]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; protein transport [GO:0015031]; regulation of telomere maintenance via telomerase [GO:0032210]; spindle assembly [GO:0051225]; Wnt signaling pathway [GO:0016055]" "chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; mitotic spindle pole [GO:0097431]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]" histone binding [GO:0042393]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+-protein ADP-ribosyltransferase activity [GO:1990404]; nucleotidyltransferase activity [GO:0016779]; zinc ion binding [GO:0008270] 0.96767 -2.7939 GKYEICKLLLK 0 0 0 0 0 0 0 0 0 12.4524 0 0 0 0 9.79795 0 0 0 0 0 0 0 0 0 0 0 0 O95292 VAPB_HUMAN Vesicle-associated membrane protein-associated protein B/C (VAMP-B/VAMP-C) (VAMP-associated protein B/C) (VAP-B/VAP-C) VAPB UNQ484/PRO983 Homo sapiens (Human) COPII-coated vesicle budding [GO:0090114]; endoplasmic reticulum membrane organization [GO:0090158]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endoplasmic reticulum-plasma membrane tethering [GO:0061817]; intracellular calcium ion homeostasis [GO:0006874]; IRE1-mediated unfolded protein response [GO:0036498]; modulation by host of viral RNA genome replication [GO:0044830]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation by virus of viral protein levels in host cell [GO:0046725]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation of viral genome replication [GO:0045070]; suppression of viral release by host [GO:0044790]; viral release from host cell [GO:0019076] cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886] beta-tubulin binding [GO:0048487]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; FFAT motif binding [GO:0033149]; microtubule binding [GO:0008017]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803] 0.91785 -0.86538 EAKPEDLMDSKLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.81458 0 0 0 0 0 0 0 0 0 O95294 RASL1_HUMAN RasGAP-activating-like protein 1 (RAS protein activator like 1) (Ras GTPase-activating-like protein) RASAL1 RASAL Homo sapiens (Human) cell differentiation [GO:0030154]; cellular response to calcium ion [GO:0071277]; intracellular signal transduction [GO:0035556]; negative regulation of Ras protein signal transduction [GO:0046580]; positive regulation of dendrite extension [GO:1903861]; regulation of GTPase activity [GO:0043087]; signal transduction [GO:0007165] cytosol [GO:0005829] GTPase activator activity [GO:0005096]; metal ion binding [GO:0046872]; phospholipid binding [GO:0005543] 0.96548 -2.2922 AALGPLGP 0 10.5841 0 0 0 0 0 0 0 0 10.292 0 9.00245 9.14637 0 0 9.90988 0 0 0 0 0 0 0 10.2201 0 0 O95295 SNAPN_HUMAN SNARE-associated protein Snapin (Biogenesis of lysosome-related organelles complex 1 subunit 7) (BLOC-1 subunit 7) (Synaptosomal-associated protein 25-binding protein) (SNAP-associated protein) SNAPIN BLOC1S7 SNAP25BP SNAPAP Homo sapiens (Human) anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; autophagosome maturation [GO:0097352]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; late endosome to lysosome transport [GO:1902774]; lysosomal lumen acidification [GO:0007042]; lysosome localization [GO:0032418]; lysosome organization [GO:0007040]; melanosome organization [GO:0032438]; negative regulation of neuron projection development [GO:0010977]; neuron cellular homeostasis [GO:0070050]; neuron projection development [GO:0031175]; neurotransmitter secretion [GO:0007269]; organelle transport along microtubule [GO:0072384]; positive regulation of late endosome to lysosome transport [GO:1902824]; protein maturation [GO:0051604]; protein-containing complex localization [GO:0031503]; regulation of endosome size [GO:0051036]; regulation of lysosome size [GO:0062196]; regulation of protein binding [GO:0043393]; regulation of synaptic vesicle exocytosis [GO:2000300]; retrograde axonal transport [GO:0008090]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle maturation [GO:0016188]; synaptic vesicle transport [GO:0048489]; terminal button organization [GO:0072553] acrosomal vesicle [GO:0001669]; axon cytoplasm [GO:1904115]; BLOC-1 complex [GO:0031083]; BORC complex [GO:0099078]; cytoplasmic side of lysosomal membrane [GO:0098574]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; manchette [GO:0002177]; perinuclear region of cytoplasm [GO:0048471]; secretory granule [GO:0030141]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672] SNARE binding [GO:0000149] 0.89936 -0.66405 EQIDNLATELCR 0 0 0 0 0 0 0 11.2627 0 0 12.1646 0 0 10.5688 0 0 0 9.59889 0 0 0 0 0 0 0 0 0 O95302 FKBP9_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP9 (PPIase FKBP9) (EC 5.2.1.8) (63 kDa FK506-binding protein) (63 kDa FKBP) (FKBP-63) (FK506-binding protein 9) (FKBP-9) (Rotamase) FKBP9 FKBP60 FKBP63 Homo sapiens (Human) protein folding [GO:0006457] endoplasmic reticulum [GO:0005783] calcium ion binding [GO:0005509]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755] 0.63067 0.40896 ISQSGDFLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1408 0 0 0 0 0 0 10.6372 0 0 O95336 6PGL_HUMAN 6-phosphogluconolactonase (6PGL) (EC 3.1.1.31) PGLS Homo sapiens (Human) "carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]" cytosol [GO:0005829]; extracellular exosome [GO:0070062] 6-phosphogluconolactonase activity [GO:0017057] 0.0057971 2.3356 ELPAAVAPAGPASLAR 9.67744 9.68384 0 0 0 11.4581 8.21213 0 9.81553 0 0 0 0 0 0 10.6188 0 0 12.2315 0 0 0 0 0 9.33764 0 10.7547 O95340 PAPS2_HUMAN Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (PAPS synthase 2) (PAPSS 2) (Sulfurylase kinase 2) (SK 2) (SK2) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (ATP-sulfurylase) (Sulfate adenylate transferase) (SAT); Adenylyl-sulfate kinase (EC 2.7.1.25) (3'-phosphoadenosine-5'-phosphosulfate synthase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (Adenylylsulfate 3'-phosphotransferase)] PAPSS2 ATPSK2 Homo sapiens (Human) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; blood coagulation [GO:0007596]; bone development [GO:0060348]; hormone metabolic process [GO:0042445]; phosphorylation [GO:0016310]; sulfate assimilation [GO:0000103] cytosol [GO:0005829] adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; sulfate adenylyltransferase (ATP) activity [GO:0004781] 0.9617 -2.0752 FVLAHGGRR 0 0 0 0 0 9.42167 0 11.2617 0 0 0 11.5693 0 9.4483 10.4256 0 0 0 0 0 0 9.03144 0 8.85125 0 0 0 O95342 ABCBB_HUMAN Bile salt export pump (EC 7.6.2.-) (ATP-binding cassette sub-family B member 11) ABCB11 BSEP Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; bile acid biosynthetic process [GO:0006699]; bile acid metabolic process [GO:0008206]; bile acid signaling pathway [GO:0038183]; canalicular bile acid transport [GO:0015722]; cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; lipid homeostasis [GO:0055088]; phospholipid homeostasis [GO:0055091]; positive regulation of bile acid secretion [GO:0120189]; protein ubiquitination [GO:0016567]; regulation of bile acid metabolic process [GO:1904251]; regulation of fatty acid beta-oxidation [GO:0031998]; regulation of gene expression [GO:0010468]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; transmembrane transport [GO:0055085]; xenobiotic export from cell [GO:0046618]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; intercellular canaliculus [GO:0046581]; intracellular canaliculus [GO:0046691]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038] ABC-type bile acid transporter activity [GO:0015432]; ABC-type xenobiotic transporter activity [GO:0008559]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; bile acid transmembrane transporter activity [GO:0015125]; canalicular bile acid transmembrane transporter activity [GO:0015126]; carbohydrate transmembrane transporter activity [GO:0015144] 0.91993 -0.92413 FYDPDQGK 0 0 0 0 0 0 10.7632 0 9.67777 0 0 0 0 0 0 0 0 0 0 0 0 0 9.08677 0 0 0 0 O95347 SMC2_HUMAN Structural maintenance of chromosomes protein 2 (SMC protein 2) (SMC-2) (Chromosome-associated protein E) (hCAP-E) (XCAP-E homolog) SMC2 CAPE SMC2L1 PRO0324 Homo sapiens (Human) cell division [GO:0051301]; kinetochore organization [GO:0051383]; meiotic chromosome condensation [GO:0010032]; meiotic chromosome segregation [GO:0045132]; mitotic chromosome condensation [GO:0007076]; positive regulation of chromosome condensation [GO:1905821]; positive regulation of chromosome segregation [GO:0051984]; positive regulation of chromosome separation [GO:1905820] chromatin [GO:0000785]; condensed chromosome [GO:0000793]; condensed nuclear chromosome [GO:0000794]; condensin complex [GO:0000796]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nuclear chromosome [GO:0000228]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; chromatin binding [GO:0003682]; single-stranded DNA binding [GO:0003697] 0.96926 -6.2061 ASNLQDLVYKNGQAGITK 10.2453 0 0 0 0 0 10.5624 10.4374 0 10.141 10.2917 0 0 0 0 10.6484 0 0 0 0 0 0 8.99899 0 0 0 0 O95352 ATG7_HUMAN Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (APG7-like) (hAGP7) (Ubiquitin-activating enzyme E1-like protein) ATG7 APG7L Homo sapiens (Human) autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; C-terminal protein lipidation [GO:0006501]; cellular response to hyperoxia [GO:0071455]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; defense response to virus [GO:0051607]; late nucleophagy [GO:0044805]; macroautophagy [GO:0016236]; piecemeal microautophagy of the nucleus [GO:0034727]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein modification process [GO:0031401]; protein lipidation [GO:0006497]; protein modification by small protein conjugation [GO:0032446]; protein transport [GO:0015031]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511] axoneme [GO:0005930]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; phagophore assembly site [GO:0000407]; secretory granule lumen [GO:0034774] Atg12 activating enzyme activity [GO:0019778]; Atg8 activating enzyme activity [GO:0019779]; protein homodimerization activity [GO:0042803] 0.72773 0.34336 LVPTLDLDK 0 0 0 8.18968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95365 ZBT7A_HUMAN Zinc finger and BTB domain-containing protein 7A (Factor binding IST protein 1) (FBI-1) (Factor that binds to inducer of short transcripts protein 1) (HIV-1 1st-binding protein 1) (Leukemia/lymphoma-related factor) (POZ and Krueppel erythroid myeloid ontogenic factor) (POK erythroid myeloid ontogenic factor) (Pokemon) (Pokemon 1) (TTF-I-interacting peptide 21) (TIP21) (Zinc finger protein 857A) ZBTB7A FBI1 LRF ZBTB7 ZNF857A Homo sapiens (Human) "B cell differentiation [GO:0030183]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; double-strand break repair via classical nonhomologous end joining [GO:0097680]; erythrocyte maturation [GO:0043249]; fat cell differentiation [GO:0045444]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein localization to nucleus [GO:0034504]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of apoptotic process [GO:0042981]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of glycolytic process [GO:0006110]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription regulatory region DNA binding [GO:2000677]" cytoplasm [GO:0005737]; DNA-dependent protein kinase complex [GO:0070418]; nucleus [GO:0005634]; site of double-strand break [GO:0035861] "DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription factor binding [GO:0140297]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; histone acetyltransferase binding [GO:0035035]; metal ion binding [GO:0046872]; nuclear androgen receptor binding [GO:0050681]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]; SMAD binding [GO:0046332]; transcription corepressor binding [GO:0001222]" 0.96114 -2.5603 VIQGAGK 15.5193 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.3436 0 0 0 0 0 0 0 0 0 0 0 O95376 ARI2_HUMAN E3 ubiquitin-protein ligase ARIH2 (ARI-2) (Protein ariadne-2 homolog) (EC 2.3.2.31) (RING-type E3 ubiquitin transferase ARIH2) (Triad1 protein) ARIH2 ARI2 TRIAD1 HT005 Homo sapiens (Human) developmental cell growth [GO:0048588]; hematopoietic stem cell proliferation [GO:0071425]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151] ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.56585 0.49959 CNICIEK 9.61695 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5394 0 0 0 0 0 9.51798 O95377 CXB5_HUMAN Gap junction beta-5 protein (Connexin-31.1) (Cx31.1) GJB5 Homo sapiens (Human) cell-cell signaling [GO:0007267]; epidermis development [GO:0008544]; epididymis development [GO:1905867]; labyrinthine layer morphogenesis [GO:0060713]; spongiotrophoblast differentiation [GO:0060708]; trophoblast giant cell differentiation [GO:0060707] connexin complex [GO:0005922] gap junction channel activity [GO:0005243] 0.91363 -0.75784 RCHECLAAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.92226 0 0 0 0 0 0 O95379 TFIP8_HUMAN Tumor necrosis factor alpha-induced protein 8 (TNF alpha-induced protein 8) (Head and neck tumor and metastasis-related protein) (MDC-3.13) (NF-kappa-B-inducible DED-containing protein) (NDED) (SCC-S2) (TNF-induced protein GG2-1) TNFAIP8 Homo sapiens (Human) negative regulation of apoptotic process [GO:0043066]; positive regulation of apoptotic process [GO:0043065] cytoplasm [GO:0005737]; nucleoplasm [GO:0005654] cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027] 0.92389 -0.99201 TVIKLAILYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.16327 0 0 0 0 0 0 0 O95382 M3K6_HUMAN Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 2) MAP3K6 ASK2 MAPKKK6 MEKK6 Homo sapiens (Human) protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; MAP kinase kinase kinase activity [GO:0004709]; protein serine kinase activity [GO:0106310] 0.87029 0.049624 CLGAHIHTPNRR 0 0 0 0 0 0 0 0 0 10.4685 9.18507 8.70584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95389 CCN6_HUMAN Cellular communication network factor 6 (CCN family member 6) (WNT1-inducible-signaling pathway protein 3) (WISP-3) CCN6 WISP3 UNQ462/PRO790/PRO956 Homo sapiens (Human) cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell death [GO:0060548]; negative regulation of cell population proliferation [GO:0008285]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; signal transduction [GO:0007165] extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; mitochondrion [GO:0005739] growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178] 0.36286 0.74585 CLVQATKWTPCSRTCGMGISNR 0 0 0 0 0 0 0 0 0 9.92413 0 0 0 0 0 9.4188 0 0 0 0 0 0 0 0 0 0 0 O95390 GDF11_HUMAN Growth/differentiation factor 11 (GDF-11) (Bone morphogenetic protein 11) (BMP-11) GDF11 BMP11 Homo sapiens (Human) amacrine cell differentiation [GO:0035881]; camera-type eye morphogenesis [GO:0048593]; cell population proliferation [GO:0008283]; mesoderm development [GO:0007498]; metanephros development [GO:0001656]; negative regulation of amacrine cell differentiation [GO:1902870]; negative regulation of cell population proliferation [GO:0008285]; nervous system development [GO:0007399]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; roof of mouth development [GO:0060021]; skeletal system development [GO:0001501]; SMAD protein signal transduction [GO:0060395]; spinal cord anterior/posterior patterning [GO:0021512]; type B pancreatic cell maturation [GO:0072560]; ureteric bud development [GO:0001657] extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991] cytokine activity [GO:0005125]; growth factor activity [GO:0008083] 0.96723 -2.3313 EAPNISR 0 0 0 0 0 0 0 0 0 0 8.58688 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2548 0 O95391 SLU7_HUMAN Pre-mRNA-splicing factor SLU7 (hSlu7) SLU7 Homo sapiens (Human) "alternative mRNA splicing, via spliceosome [GO:0000380]; cellular response to heat [GO:0034605]; intracellular protein transport [GO:0006886]; mRNA 3'-splice site recognition [GO:0000389]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]" catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; small nuclear ribonucleoprotein complex [GO:0030532]; spliceosomal complex [GO:0005681] pre-mRNA 3'-splice site binding [GO:0030628]; second spliceosomal transesterification activity [GO:0000386]; zinc ion binding [GO:0008270] 0.92665 -1.2147 CCHSFFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2353 0 0 0 0 0 0 9.04486 0 0 0 O95393 BMP10_HUMAN Bone morphogenetic protein 10 (BMP-10) BMP10 Homo sapiens (Human) activin receptor signaling pathway [GO:0032924]; adult heart development [GO:0007512]; atrial cardiac muscle tissue morphogenesis [GO:0055009]; BMP signaling pathway [GO:0030509]; cardiac muscle cell proliferation [GO:0060038]; cell adhesion [GO:0007155]; heart trabecula formation [GO:0060347]; kidney development [GO:0001822]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of endothelial cell migration [GO:0010596]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cartilage development [GO:0061036]; positive regulation of cell proliferation involved in heart morphogenesis [GO:2000138]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of sarcomere organization [GO:0060298]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle hypertrophy in response to stress [GO:1903242]; sarcomere organization [GO:0045214]; SMAD protein signal transduction [GO:0060395]; ventricular cardiac muscle cell development [GO:0055015]; ventricular cardiac muscle tissue morphogenesis [GO:0055010] cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Z disc [GO:0030018] cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; receptor serine/threonine kinase binding [GO:0033612]; telethonin binding [GO:0031433] 0.84783 0.16989 SNIIYDSTAR 0 0 0 0 0 0 0 0 0 0 9.37738 0 0 0 0 0 9.49536 10.0988 0 0 0 0 0 0 0 0 0 O95394 AGM1_HUMAN Phosphoacetylglucosamine mutase (PAGM) (EC 5.4.2.3) (Acetylglucosamine phosphomutase) (N-acetylglucosamine-phosphate mutase) (Phosphoglucomutase-3) (PGM 3) PGM3 AGM1 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; glucosamine metabolic process [GO:0006041]; hemopoiesis [GO:0030097]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; spermatogenesis [GO:0007283]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048] cytosol [GO:0005829] magnesium ion binding [GO:0000287]; phosphoacetylglucosamine mutase activity [GO:0004610] 0.87099 0.041939 MGLLAVLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.71852 0 0 0 O95395 GCNT3_HUMAN "Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 (EC 2.4.1.102) (EC 2.4.1.148) (EC 2.4.1.150) (C2GnT-mucin type) (C2GnT-M) (hC2GnT-M) (Core 2/core 4 beta-1,6-N-acetylglucosaminyltransferase) (C2/4GnT)" GCNT3 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; intestinal absorption [GO:0050892]; kidney morphogenesis [GO:0060993]; O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493]; tissue morphogenesis [GO:0048729] extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; membrane [GO:0016020] "acetylgalactosaminyl-O-glycosyl-seryl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity [GO:0106325]; acetylgalactosaminyl-O-glycosyl-threonyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity [GO:0106326]; acetylglucosaminyltransferase activity [GO:0008375]; beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity [GO:0003829]; N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity [GO:0008109]" 0.87698 0.0026213 VQADLNCMEDLLQSSVPWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3413 0 0 O95396 MOCS3_HUMAN Adenylyltransferase and sulfurtransferase MOCS3 (Molybdenum cofactor synthesis protein 3) (Molybdopterin synthase sulfurylase) (MPT synthase sulfurylase) [Includes: Molybdopterin-synthase adenylyltransferase (EC 2.7.7.80) (Adenylyltransferase MOCS3) (Sulfur carrier protein MOCS2A adenylyltransferase); Molybdopterin-synthase sulfurtransferase (EC 2.8.1.11) (Sulfur carrier protein MOCS2A sulfurtransferase) (Sulfurtransferase MOCS3)] MOCS3 UBA4 Homo sapiens (Human) Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdopterin cofactor metabolic process [GO:0043545]; protein urmylation [GO:0032447]; tRNA thio-modification [GO:0034227]; tRNA wobble position uridine thiolation [GO:0002143]; tRNA wobble uridine modification [GO:0002098] cytoplasm [GO:0005737]; cytosol [GO:0005829] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molybdopterin-synthase adenylyltransferase activity [GO:0061605]; molybdopterin-synthase sulfurtransferase activity [GO:0061604]; nucleotidyltransferase activity [GO:0016779]; sulfurtransferase activity [GO:0016783]; thiosulfate sulfurtransferase activity [GO:0004792]; URM1 activating enzyme activity [GO:0042292] 0.87021 0.047579 DVVGGLMAWAAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.54643 0 0 0 0 0 0 0 0 O95398 RPGF3_HUMAN Rap guanine nucleotide exchange factor 3 (Exchange factor directly activated by cAMP 1) (Exchange protein directly activated by cAMP 1) (EPAC 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP) (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) RAPGEF3 CGEF1 EPAC EPAC1 Homo sapiens (Human) adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; associative learning [GO:0008306]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; establishment of endothelial barrier [GO:0061028]; negative regulation of syncytium formation by plasma membrane fusion [GO:0034242]; positive regulation of angiogenesis [GO:0045766]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of syncytium formation by plasma membrane fusion [GO:0060143]; Rap protein signal transduction [GO:0032486]; Ras protein signal transduction [GO:0007265]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of angiogenesis [GO:0045765]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; signal transduction [GO:0007165] endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane [GO:0016020]; microvillus [GO:0005902]; plasma membrane [GO:0005886] cAMP binding [GO:0030552]; guanyl-nucleotide exchange factor activity [GO:0005085]; protein domain specific binding [GO:0019904] 0.96111 -2.057 LSNLLREQWPER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.47131 0 0 0 0 0 0 O95399 UTS2_HUMAN Urotensin-2 (Urotensin II) (U-II) (UII) UTS2 UNQ525/PRO1068 Homo sapiens (Human) blood vessel diameter maintenance [GO:0097746]; chemical synaptic transmission [GO:0007268]; muscle contraction [GO:0006936]; regulation of blood pressure [GO:0008217] extracellular region [GO:0005576]; extracellular space [GO:0005615]; synapse [GO:0045202] hormone activity [GO:0005179]; signaling receptor binding [GO:0005102] 0.01199 1.7621 LTPEELER 0 0 0 0 0 0 0 0 0 12.4477 12.2432 12.6263 0 9.43461 0 0 0 0 0 10.4337 11.1133 10.1298 10.157 0 0 0 0 O95400 CD2B2_HUMAN CD2 antigen cytoplasmic tail-binding protein 2 (CD2 cytoplasmic domain-binding protein 2) (CD2 tail-binding protein 2) (U5 snRNP 52K protein) (U5-52K) CD2BP2 KIAA1178 Homo sapiens (Human) spliceosomal tri-snRNP complex assembly [GO:0000244] cytoplasm [GO:0005737]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U5 snRNP [GO:0005682] ribonucleoprotein complex binding [GO:0043021] 0.89001 -0.47414 LDPPGGQFYNSKR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.43734 0 9.90075 0 9.82075 0 0 0 0 9.72688 8.00304 0 0 0 O95402 MED26_HUMAN Mediator of RNA polymerase II transcription subunit 26 (Activator-recruited cofactor 70 kDa component) (ARC70) (Cofactor required for Sp1 transcriptional activation subunit 7) (CRSP complex subunit 7) (Mediator complex subunit 26) (Transcriptional coactivator CRSP70) MED26 ARC70 CRSP7 Homo sapiens (Human) positive regulation of gene expression [GO:0010628]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription initiation at RNA polymerase II promoter [GO:0006367] core mediator complex [GO:0070847]; mediator complex [GO:0016592]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712] 0.97004 -3.2327 LERDENDKHSGK 0 0 0 0 0 0 8.33566 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95405 ZFYV9_HUMAN Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Novel serine protease) (NSP) (Receptor activation anchor) (hSARA) (Smad anchor for receptor activation) ZFYVE9 MADHIP SARA SMADIP Homo sapiens (Human) endocytosis [GO:0006897]; endosomal transport [GO:0016197]; transforming growth factor beta receptor signaling pathway [GO:0007179] cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; intracellular membrane-bounded organelle [GO:0043231]; protein-containing complex [GO:0032991] 1-phosphatidylinositol binding [GO:0005545]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904] 0.93008 -1.2448 AFCLALCPHLK 0 0 0 9.52781 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2467 0 0 0 0 0 10.112 10.2511 O95409 ZIC2_HUMAN Zinc finger protein ZIC 2 (Zinc finger protein of the cerebellum 2) ZIC2 Homo sapiens (Human) brain development [GO:0007420]; cell differentiation [GO:0030154]; central nervous system development [GO:0007417]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]; visual perception [GO:0007601] cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.90458 -0.70706 QQCIKQELICK 0 0 0 0 0 0 0 0 0 0 10.2427 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95425 SVIL_HUMAN Supervillin (Archvillin) (p205/p250) SVIL Homo sapiens (Human) actin filament severing [GO:0051014]; actin polymerization or depolymerization [GO:0008154]; barbed-end actin filament capping [GO:0051016]; positive regulation of cytokinesis [GO:0032467]; skeletal muscle tissue development [GO:0007519] actin cytoskeleton [GO:0015629]; cell projection [GO:0042995]; cleavage furrow [GO:0032154]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; microtubule minus-end [GO:0036449]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; podosome [GO:0002102] "actin filament binding [GO:0051015]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]" 0.96901 -7.5857 ALAKDQTNEGK 9.17493 9.40107 0 0 0 0 10.9028 9.41638 0 0 11.4608 8.44357 10.6822 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95428 PPN_HUMAN Papilin PAPLN UNQ2420/PRO4977 Homo sapiens (Human) extracellular matrix organization [GO:0030198]; negative regulation of peptidase activity [GO:0010466] extracellular region [GO:0005576] serine-type endopeptidase inhibitor activity [GO:0004867] 0.96374 -2.1066 ERPCYSQRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.1119 0 O95447 LCA5L_HUMAN Lebercilin-like protein (Leber congenital amaurosis 5-like protein) LCA5L C21orf13 Homo sapiens (Human) intraciliary transport [GO:0042073] axoneme [GO:0005930] 0.96303 -2.1262 AIGKYENSQNNLPQIMAK 0 0 0 0 8.35204 0 0 0 8.71328 8.9326 0 0 0 9.46704 0 0 0 0 0 9.96542 0 0 0 0 0 0 0 O95450 ATS2_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAM-TS 2) (ADAM-TS2) (ADAMTS-2) (EC 3.4.24.14) (Procollagen I N-proteinase) (PC I-NP) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen N-endopeptidase) (pNPI) ADAMTS2 PCINP PCPNI Homo sapiens (Human) collagen catabolic process [GO:0030574]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; lung development [GO:0030324]; protein processing [GO:0016485]; skin development [GO:0043588]; spermatogenesis [GO:0007283] collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576] metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270] 0.55922 0.54603 ACNPQECSQPVWVTGEWEPCSQTCGR 9.53739 9.30198 0 9.44969 9.60444 9.38506 10.0174 0 8.84934 0 9.35061 9.01639 10.1221 0 0 9.99915 9.6422 0 0 0 11.2939 0 8.0421 0 0 0 0 O95452 CXB6_HUMAN Gap junction beta-6 protein (Connexin-30) (Cx30) GJB6 Homo sapiens (Human) aging [GO:0007568]; apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; cellular response to glucose stimulus [GO:0071333]; ear morphogenesis [GO:0042471]; gap junction assembly [GO:0016264]; gap junction-mediated intercellular transport [GO:1990349]; inner ear development [GO:0048839]; maintenance of blood-brain barrier [GO:0035633]; negative regulation of cell population proliferation [GO:0008285]; response to electrical stimulus [GO:0051602]; response to lipopolysaccharide [GO:0032496]; sensory perception of sound [GO:0007605]; sinoatrial node development [GO:0003163]; transmembrane transport [GO:0055085] actin filament [GO:0005884]; apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; connexin complex [GO:0005922]; cytosol [GO:0005829]; gap junction [GO:0005921] actin filament binding [GO:0051015]; beta-tubulin binding [GO:0048487]; gap junction channel activity [GO:0005243]; gap junction channel activity involved in cell communication by electrical coupling [GO:1903763]; microtubule binding [GO:0008017] 0.88504 -0.29547 NDFKDIEDIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.67805 0 0 0 0 0 0 O95453 PARN_HUMAN Poly(A)-specific ribonuclease PARN (EC 3.1.13.4) (Deadenylating nuclease) (Deadenylation nuclease) (Polyadenylate-specific ribonuclease) PARN DAN Homo sapiens (Human) "box H/ACA RNA 3'-end processing [GO:0000495]; female gamete generation [GO:0007292]; miRNA catabolic process [GO:0010587]; ncRNA deadenylation [GO:0110008]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of telomerase RNA localization to Cajal body [GO:1904872]; RNA modification [GO:0009451]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; telomerase RNA stabilization [GO:0090669]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634] cation binding [GO:0043169]; metal ion binding [GO:0046872]; mRNA 3'-UTR binding [GO:0003730]; nuclease activity [GO:0004518]; poly(A)-specific ribonuclease activity [GO:0004535]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; telomerase RNA binding [GO:0070034] 0.63115 0.40617 RLKETPFNPPK 0 0 0 0 0 0 0 0 0 10.461 0 0 0 0 0 0 9.92631 0 0 0 0 0 0 0 0 0 0 O95456 PSMG1_HUMAN Proteasome assembly chaperone 1 (PAC-1) (Chromosome 21 leucine-rich protein) (C21-LRP) (Down syndrome critical region protein 2) PSMG1 C21LRP DSCR2 PAC1 Homo sapiens (Human) cerebellar granule cell precursor proliferation [GO:0021930]; chaperone-mediated protein complex assembly [GO:0051131]; proteasome core complex assembly [GO:0080129] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein folding chaperone complex [GO:0101031] molecular adaptor activity [GO:0060090]; proteasome binding [GO:0070628] 0.84209 0.18249 IPAILYLCYTDVMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4171 0 0 0 0 0 0 0 0 0 0 O95460 MATN4_HUMAN Matrilin-4 MATN4 Homo sapiens (Human) extracellular matrix organization [GO:0030198] collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; matrilin complex [GO:0120216] calcium ion binding [GO:0005509] 0.88521 -0.23311 LEDLENQLANQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.8806 O95461 LARG1_HUMAN "Xylosyl- and glucuronyltransferase LARGE1 (EC 2.4.-.-) (Acetylglucosaminyltransferase-like 1A) (Glycosyltransferase-like protein) (LARGE xylosyl- and glucuronyltransferase 1) [Includes: Alpha-1,3-xylosyltransferase LARGE1 (EC 2.4.2.-); Beta-1,3-glucuronyltransferase LARGE1 (EC 2.4.1.-)]" LARGE1 KIAA0609 LARGE Homo sapiens (Human) acetylcholine receptor signaling pathway [GO:0095500]; astrocyte differentiation [GO:0048708]; basement membrane organization [GO:0071711]; blood vessel development [GO:0001568]; cardiac muscle cell development [GO:0055013]; chemical synaptic transmission [GO:0007268]; cytoskeleton organization [GO:0007010]; dentate gyrus development [GO:0021542]; gene expression [GO:0010467]; glycoprotein biosynthetic process [GO:0009101]; glycosphingolipid biosynthetic process [GO:0006688]; muscle cell cellular homeostasis [GO:0046716]; N-acetylglucosamine metabolic process [GO:0006044]; nerve development [GO:0021675]; neuron migration [GO:0001764]; plasma membrane organization [GO:0007009]; post-translational protein modification [GO:0043687]; potassium ion transmembrane transport [GO:0071805]; principal sensory nucleus of trigeminal nerve development [GO:0021740]; protein glycosylation [GO:0006486]; protein localization to membrane [GO:0072657]; protein O-linked glycosylation [GO:0006493]; protein O-linked mannosylation [GO:0035269]; protein phosphorylation [GO:0006468]; protein-containing complex assembly [GO:0065003]; reactive gliosis [GO:0150103]; regulation of protein binding [GO:0043393]; response to mechanical stimulus [GO:0009612]; retina layer formation [GO:0010842]; retina vasculature development in camera-type eye [GO:0061298]; skeletal muscle fiber development [GO:0048741]; skeletal muscle organ development [GO:0060538]; skeletal muscle tissue regeneration [GO:0043403]; synaptic assembly at neuromuscular junction [GO:0051124]; water transport [GO:0006833] Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; neuromuscular junction [GO:0031594]; plasma membrane [GO:0005886] acetylglucosaminyltransferase activity [GO:0008375]; glucuronosyltransferase activity [GO:0015020]; glycosyltransferase activity [GO:0016757]; hexosyltransferase activity [GO:0016758]; manganese ion binding [GO:0030145]; UDP-xylosyltransferase activity [GO:0035252]; xylosyltransferase activity [GO:0042285] 0.96533 -2.3711 LGICRGRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.286 0 0 O95471 CLD7_HUMAN Claudin-7 (CLDN-7) CLDN7 CEPTRL2 CPETRL2 Homo sapiens (Human) bicellular tight junction assembly [GO:0070830]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell adhesion [GO:0007162]; negative regulation of protein-containing complex assembly [GO:0031333]; positive regulation of cell motility [GO:2000147]; positive regulation of cell population proliferation [GO:0008284]; response to ethanol [GO:0045471] apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; lateral plasma membrane [GO:0016328]; plasma membrane [GO:0005886] cell adhesion molecule binding [GO:0050839]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; structural molecule activity [GO:0005198] 0.69419 0.3837 VPRSYPKSNSSK 0 0 0 0 0 0 0 0 0 0 0 0 10.1175 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95475 SIX6_HUMAN Homeobox protein SIX6 (Homeodomain protein OPTX2) (Optic homeobox 2) (Sine oculis homeobox homolog 6) SIX6 OPTX2 SIX9 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; eye development [GO:0001654]; regulation of transcription by RNA polymerase II [GO:0006357]; visual perception [GO:0007601] chromatin [GO:0000785]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.95475 -1.5018 LRGRPLGPVDK 0 0 0 10.189 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95477 ABCA1_HUMAN Phospholipid-transporting ATPase ABCA1 (EC 7.6.2.1) (ATP-binding cassette sub-family A member 1) (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1) (Cholesterol efflux regulatory protein) ABCA1 ABC1 CERP Homo sapiens (Human) "adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to retinoic acid [GO:0071300]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; endosomal transport [GO:0016197]; export across plasma membrane [GO:0140115]; G protein-coupled receptor signaling pathway [GO:0007186]; high-density lipoprotein particle assembly [GO:0034380]; intracellular cholesterol transport [GO:0032367]; lysosome organization [GO:0007040]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; peptide secretion [GO:0002790]; phagocytosis, engulfment [GO:0006911]; phospholipid efflux [GO:0033700]; phospholipid homeostasis [GO:0055091]; phospholipid translocation [GO:0045332]; platelet dense granule organization [GO:0060155]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of high-density lipoprotein particle assembly [GO:0090108]; protein lipidation [GO:0006497]; protein secretion [GO:0009306]; protein transmembrane transport [GO:0071806]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of high-density lipoprotein particle assembly [GO:0090107]; response to laminar fluid shear stress [GO:0034616]; reverse cholesterol transport [GO:0043691]; signal release [GO:0023061]" endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; intracellular vesicle [GO:0097708]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886] ABC-type transporter activity [GO:0140359]; apolipoprotein A-I binding [GO:0034186]; apolipoprotein A-I receptor activity [GO:0034188]; apolipoprotein binding [GO:0034185]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase binding [GO:0051117]; ATPase-coupled transmembrane transporter activity [GO:0042626]; cholesterol binding [GO:0015485]; cholesterol transfer activity [GO:0120020]; floppase activity [GO:0140328]; phosphatidylcholine binding [GO:0031210]; phosphatidylcholine floppase activity [GO:0090554]; phosphatidylserine floppase activity [GO:0090556]; phospholipid transporter activity [GO:0005548]; protein transmembrane transporter activity [GO:0008320]; signaling receptor binding [GO:0005102]; small GTPase binding [GO:0031267]; sphingolipid floppase activity [GO:0046623]; syntaxin binding [GO:0019905] 0.96943 -4.7622 LTQQQFVALLWK 0 8.77656 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.59908 9.51706 0 11.053 0 0 9.97054 O95478 NSA2_HUMAN Ribosome biogenesis protein NSA2 homolog (Hairy cell leukemia protein 1) (TGF-beta-inducible nuclear protein 1) NSA2 TINP1 HUSSY-29 Homo sapiens (Human) maturation of 5.8S rRNA [GO:0000460]; maturation of LSU-rRNA [GO:0000470] "nucleolus [GO:0005730]; preribosome, large subunit precursor [GO:0030687]" RNA binding [GO:0003723] 0.96773 -3.674 KESREAHER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.64769 8.73162 0 0 0 0 0 O95479 G6PE_HUMAN GDH/6PGL endoplasmic bifunctional protein [Includes: Hexose-6-phosphate dehydrogenase (Glucose 1-dehydrogenase) (GDH) (EC 1.1.1.47) (Glucose-6-phosphate dehydrogenase) (EC 1.1.1.363); 6-phosphogluconolactonase (6PGL) (EC 3.1.1.31)] H6PD GDH Homo sapiens (Human) "glucose metabolic process [GO:0006006]; pentose-phosphate shunt, oxidative branch [GO:0009051]; regulation of cortisol biosynthetic process [GO:2000064]; response to alcohol [GO:0097305]; response to nutrient levels [GO:0031667]" endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; mitochondrion [GO:0005739] 6-phosphogluconolactonase activity [GO:0017057]; carbohydrate binding [GO:0030246]; glucose 1-dehydrogenase (NAD+) activity [GO:0047934]; glucose 1-dehydrogenase (NADP+) activity [GO:0047935]; glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]; glucose-6-phosphate dehydrogenase activity [GO:0004345]; NADP binding [GO:0050661] 0.84923 0.1152 VEIIMKETVDAEGR 0 0 0 0 0 0 0 0 0 0 0 0 8.56171 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95490 AGRL2_HUMAN Adhesion G protein-coupled receptor L2 (Calcium-independent alpha-latrotoxin receptor 2) (CIRL-2) (Latrophilin homolog 1) (Latrophilin-2) (Lectomedin-1) ADGRL2 KIAA0786 LEC1 LPHH1 LPHN2 Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; brain development [GO:0007420]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] membrane [GO:0016020]; neuron projection [GO:0043005] carbohydrate binding [GO:0030246]; G protein-coupled receptor activity [GO:0004930]; latrotoxin receptor activity [GO:0016524] 0.79591 0.24352 AALPFGLVR 0 11.7182 11.7826 11.833 11.9309 11.8131 0 11.8912 11.8267 12.2498 12.2931 12.3894 0 0 11.4306 0 0 12.1105 11.8743 11.756 11.7821 11.5683 11.5469 0 0 0 0 O95497 VNN1_HUMAN Pantetheinase (EC 3.5.1.92) (Pantetheine hydrolase) (Tiff66) (Vascular non-inflammatory molecule 1) (Vanin-1) VNN1 Homo sapiens (Human) acute inflammatory response [GO:0002526]; cell-cell adhesion [GO:0098609]; chronic inflammatory response [GO:0002544]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; pantothenate metabolic process [GO:0015939]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of T cell differentiation in thymus [GO:0033089]; response to oxidative stress [GO:0006979] azurophil granule membrane [GO:0035577]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886] pantetheine hydrolase activity [GO:0017159] 0.812 0.22413 DLCCHLSYK 0 0 0 0 0 0 0 0 0 0 0 10.5934 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95500 CLD14_HUMAN Claudin-14 CLDN14 UNQ777/PRO1571 Homo sapiens (Human) bicellular tight junction assembly [GO:0070830]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; protein-containing complex assembly [GO:0065003] bicellular tight junction [GO:0005923]; endoplasmic reticulum [GO:0005783]; plasma membrane [GO:0005886] identical protein binding [GO:0042802]; structural molecule activity [GO:0005198] 0.93319 -1.2657 CTRCAKGTPAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.13947 0 0 0 0 0 0 0 0 O95521 PRAM1_HUMAN PRAME family member 1 PRAMEF1 Homo sapiens (Human) negative regulation of apoptotic process [GO:0043066]; negative regulation of cell differentiation [GO:0045596]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of cell population proliferation [GO:0008284] cytoplasm [GO:0005737] 0.82232 0.21657 GLVHLCCSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.83637 0 0 0 0 0 0 0 0 0 0 0 O95544 NADK_HUMAN NAD kinase (EC 2.7.1.23) (Poly(P)/ATP NAD kinase) NADK Homo sapiens (Human) ATP metabolic process [GO:0046034]; NAD metabolic process [GO:0019674]; NADP biosynthetic process [GO:0006741]; phosphorylation [GO:0016310] cytosol [GO:0005829] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; NAD+ kinase activity [GO:0003951] 0.42993 0.65817 KQAHFEEEEEEEEEG 0 0 0 9.07428 9.49388 9.2724 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95567 CV031_HUMAN Uncharacterized protein C22orf31 C22orf31 Homo sapiens (Human) 0.94004 -1.3015 ATQQARKR 0 0 0 0 0 0 0 0 0 0 9.78952 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95571 ETHE1_HUMAN "Persulfide dioxygenase ETHE1, mitochondrial (EC 1.13.11.18) (Ethylmalonic encephalopathy protein 1) (Hepatoma subtracted clone one protein) (Sulfur dioxygenase ETHE1)" ETHE1 HSCO Homo sapiens (Human) glutathione metabolic process [GO:0006749]; hydrogen sulfide metabolic process [GO:0070813] cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; sulfur dioxygenase activity [GO:0050313] 0.87209 0.031382 LTLSCEEFVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.25974 0 0 0 0 0 O95573 ACSL3_HUMAN Fatty acid CoA ligase Acsl3 (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 3) (LACS 3) (Long-chain-fatty-acid--CoA ligase 3) (EC 6.2.1.3) (Medium-chain acyl-CoA ligase Acsl3) (EC 6.2.1.2) ACSL3 ACS3 FACL3 LACS3 Homo sapiens (Human) fatty acid metabolic process [GO:0006631]; long-chain fatty acid import into cell [GO:0044539]; long-chain fatty acid metabolic process [GO:0001676]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]; neuron differentiation [GO:0030182]; positive regulation of Golgi to plasma membrane protein transport [GO:0042998]; positive regulation of phosphatidylcholine biosynthetic process [GO:2001247]; positive regulation of secretion [GO:0051047]; very-low-density lipoprotein particle assembly [GO:0034379] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; lipid droplet [GO:0005811]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal membrane [GO:0005778]; plasma membrane [GO:0005886] arachidonate-CoA ligase activity [GO:0047676]; ATP binding [GO:0005524]; long-chain fatty acid-CoA ligase activity [GO:0004467]; medium-chain fatty acid-CoA ligase activity [GO:0031956]; palmitoyl-CoA ligase activity [GO:0090433]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901] 0.8433 0.13995 DIVSLVPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.21898 O95602 RPA1_HUMAN DNA-directed RNA polymerase I subunit RPA1 (RNA polymerase I subunit A1) (EC 2.7.7.6) (A190) (DNA-directed RNA polymerase I largest subunit) (DNA-directed RNA polymerase I subunit A) (RNA polymerase I 194 kDa subunit) (RPA194) POLR1A Homo sapiens (Human) negative regulation of protein localization to nucleolus [GO:1904750] chromosome [GO:0005694]; nucleoplasm [GO:0005654]; RNA polymerase I complex [GO:0005736] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; RNA polymerase I activity [GO:0001054] 0.9222 -1.1376 ASAFRNVNTR 0 9.2516 0 0 0 0 0 0 0 9.65449 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.77349 0 0 O95613 PCNT_HUMAN Pericentrin (Kendrin) (Pericentrin-B) PCNT KIAA0402 PCNT2 Homo sapiens (Human) cilium assembly [GO:0060271]; microtubule cytoskeleton organization [GO:0000226]; mitotic spindle organization [GO:0007052]; positive regulation of intracellular protein transport [GO:0090316]; signal transduction [GO:0007165] centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; microtubule [GO:0005874] calmodulin binding [GO:0005516]; molecular adaptor activity [GO:0060090] 0.96897 -13.584 AELEKIFQDK 15.1321 10.521 14.752 10.2855 0 0 14.6058 14.8587 14.7565 0 12.125 9.51912 0 8.68696 8.82985 10.3004 8.90725 10.7746 10.3063 0 10.0867 11.3103 11.2599 11.3325 10.4106 10.1515 12.1339 O95620 DUS4L_HUMAN tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like (EC 1.3.1.90) (pp35) (tRNA-dihydrouridine synthase 4-like) DUS4L Homo sapiens (Human) tRNA dihydrouridine synthesis [GO:0002943] flavin adenine dinucleotide binding [GO:0050660]; tRNA dihydrouridine synthase activity [GO:0017150] 0.96884 -3.3761 LLSDAAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.06595 0 0 O95622 ADCY5_HUMAN Adenylate cyclase type 5 (EC 4.6.1.1) (ATP pyrophosphate-lyase 5) (Adenylate cyclase type V) (Adenylyl cyclase 5) (AC5) ADCY5 Homo sapiens (Human) adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; cAMP biosynthetic process [GO:0006171]; cellular response to forskolin [GO:1904322]; G protein-coupled adenosine receptor signaling pathway [GO:0001973]; intracellular signal transduction [GO:0035556]; locomotory behavior [GO:0007626]; neuromuscular process controlling balance [GO:0050885]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178] cilium [GO:0005929]; membrane [GO:0016020]; plasma membrane [GO:0005886] adenylate cyclase activity [GO:0004016]; adenylate cyclase binding [GO:0008179]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110] 0.95972 -1.9439 GSTKKPGGAVTPQQQQR 0 0 0 0 10.831 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2206 0 0 0 0 9.05452 0 O95625 ZBT11_HUMAN Zinc finger and BTB domain-containing protein 11 ZBTB11 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleolus [GO:0005730]; nucleoplasm [GO:0005654] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96775 -2.7915 DYKCPLCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.88406 0 0 0 0 0 0 0 0 0 0 O95630 STABP_HUMAN STAM-binding protein (EC 3.4.19.-) (Associated molecule with the SH3 domain of STAM) (Endosome-associated ubiquitin isopeptidase) STAMBP AMSH Homo sapiens (Human) hippocampal neuron apoptotic process [GO:0110088]; mitotic cytokinesis [GO:0000281]; negative regulation of hippocampal neuron apoptotic process [GO:0110091]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of Ras protein signal transduction [GO:0046580]; positive regulation of cell population proliferation [GO:0008284]; protein deubiquitination [GO:0016579]; protein K63-linked deubiquitination [GO:0070536]; receptor signaling pathway via JAK-STAT [GO:0007259] cleavage furrow [GO:0032154]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] deubiquitinase activity [GO:0101005]; K63-linked deubiquitinase activity [GO:0061578]; metal ion binding [GO:0046872]; metal-dependent deubiquitinase activity [GO:0140492]; protein domain specific binding [GO:0019904] 0.93162 -1.2615 GVETCGILCGK 0 0 0 0 0 0 0 9.28626 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95631 NET1_HUMAN Netrin-1 (Epididymis tissue protein Li 131P) NTN1 NTN1L Homo sapiens (Human) "anterior/posterior axon guidance [GO:0033564]; apoptotic process [GO:0006915]; Cdc42 protein signal transduction [GO:0032488]; cell-cell adhesion [GO:0098609]; chemorepulsion of axon [GO:0061643]; glial cell proliferation [GO:0014009]; inner ear morphogenesis [GO:0042472]; mammary gland duct morphogenesis [GO:0060603]; motor neuron migration [GO:0097475]; negative regulation of axon extension [GO:0030517]; nuclear migration [GO:0007097]; positive regulation of axon extension [GO:0045773]; positive regulation of cell motility [GO:2000147]; positive regulation of glial cell proliferation [GO:0060252]; Ras protein signal transduction [GO:0007265]; regulation of glial cell migration [GO:1903975]; regulation of synapse assembly [GO:0051963]; regulation of transcription by RNA polymerase II [GO:0006357]; substrate-dependent cell migration, cell extension [GO:0006930]" actin cytoskeleton [GO:0015629]; basement membrane [GO:0005604]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96787 -3.8229 CKCNGHAAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.62311 9.33286 0 0 0 0 0 0 0 0 0 O95639 CPSF4_HUMAN Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog) CPSF4 CPSF30 NAR NEB1 Homo sapiens (Human) pre-mRNA cleavage required for polyadenylation [GO:0098789] intracellular membrane-bounded organelle [GO:0043231]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleoplasm [GO:0005654] RNA binding [GO:0003723]; sequence-specific double-stranded DNA binding [GO:1990837]; zinc ion binding [GO:0008270] 0.90603 -0.72805 DCPWYDRGFCK 0 0 0 0 0 0 0 0 9.83172 10.0067 10.0901 10.1967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95644 NFAC1_HUMAN "Nuclear factor of activated T-cells, cytoplasmic 1 (NF-ATc1) (NFATc1) (NFAT transcription complex cytosolic component) (NF-ATc) (NFATc)" NFATC1 NFAT2 NFATC Homo sapiens (Human) aortic valve morphogenesis [GO:0003180]; calcineurin-NFAT signaling cascade [GO:0033173]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to tumor necrosis factor [GO:0071356]; intracellular signal transduction [GO:0035556]; mononuclear cell differentiation [GO:1903131]; negative regulation of vascular associated smooth muscle cell differentiation [GO:1905064]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pulmonary valve morphogenesis [GO:0003184]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; FK506 binding [GO:0005528]; mitogen-activated protein kinase p38 binding [GO:0048273]; nucleic acid binding [GO:0003676]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription coactivator binding [GO:0001223]" 0.93163 -1.2615 ASVTEESWLGAR 0 0 0 0 12.5661 9.5542 0 0 0 0 9.11481 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95661 DIRA3_HUMAN GTP-binding protein Di-Ras3 (Distinct subgroup of the Ras family member 3) (Rho-related GTP-binding protein RhoI) DIRAS3 ARHI NOEY2 RHOI Homo sapiens (Human) regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of gene expression by genomic imprinting [GO:0006349]; small GTPase mediated signal transduction [GO:0007264] plasma membrane [GO:0005886] GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.19249 0.93212 VVVVGTAGVGK 0 0 0 0 0 0 0 0 0 9.7925 9.89603 9.81186 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95677 EYA4_HUMAN Eyes absent homolog 4 (EC 3.1.3.48) EYA4 Homo sapiens (Human) anatomical structure development [GO:0048856]; anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; DNA repair [GO:0006281]; inner ear development [GO:0048839]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; positive regulation of DNA repair [GO:0045739]; visual perception [GO:0007601] cytoplasm [GO:0005737]; nucleus [GO:0005634] metal ion binding [GO:0046872]; protein tyrosine phosphatase activity [GO:0004725] 0.95877 -1.7796 IGKESCFERIMQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.83605 0 O95696 BRD1_HUMAN Bromodomain-containing protein 1 (BR140-like protein) (Bromodomain and PHD finger-containing protein 2) BRD1 BRL BRPF2 Homo sapiens (Human) chromatin remodeling [GO:0006338]; erythrocyte maturation [GO:0043249]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355]; regulation of hemopoiesis [GO:1903706]; regulation of transcription by RNA polymerase II [GO:0006357]; response to electrical stimulus [GO:0051602]; response to immobilization stress [GO:0035902] dendrite [GO:0030425]; histone H3-K14 acetyltransferase complex [GO:0036409]; MOZ/MORF histone acetyltransferase complex [GO:0070776]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; perikaryon [GO:0043204] histone binding [GO:0042393]; histone reader activity [GO:0140566]; metal ion binding [GO:0046872] 0.96952 -4.9208 HPMDFATMRKR 0 12.8119 10.6744 0 0 9.72306 0 10.8385 0 0 9.26554 0 0 0 0 0 9.58731 9.33239 9.43482 0 9.67133 0 11.1477 0 0 11.2425 10.6703 O95714 HERC2_HUMAN E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2) HERC2 Homo sapiens (Human) DNA damage response [GO:0006974]; DNA repair [GO:0006281]; intracellular protein transport [GO:0006886]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; spermatogenesis [GO:0007283] centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] guanyl-nucleotide exchange factor activity [GO:0005085]; SUMO binding [GO:0032183]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270] 0.96932 -6.544 DLINTGICESSGK 9.08911 9.34041 10.2795 0 0 0 0 0 0 9.70762 0 0 0 0 9.11868 0 0 0 0 0 0 0 0 0 9.34001 0 0 O95718 ERR2_HUMAN Steroid hormone receptor ERR2 (ERR beta-2) (Estrogen receptor-like 2) (Estrogen-related receptor beta) (ERR-beta) (Nuclear receptor subfamily 3 group B member 2) ESRRB ERRB2 ESRL2 NR3B2 Homo sapiens (Human) cell dedifferentiation [GO:0043697]; cell population proliferation [GO:0008283]; inner ear development [GO:0048839]; negative regulation of stem cell differentiation [GO:2000737]; photoreceptor cell maintenance [GO:0045494]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071931]; positive regulation of transcription involved in G2/M transition of mitotic cell cycle [GO:0090282]; regulation of DNA-templated transcription [GO:0006355]; regulation of stem cell division [GO:2000035]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell division [GO:0017145]; stem cell population maintenance [GO:0019827] chromatin [GO:0000785]; condensed chromosome [GO:0000793]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "cis-regulatory region sequence-specific DNA binding [GO:0000987]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; estrogen response element binding [GO:0034056]; nuclear steroid receptor activity [GO:0003707]; nucleic acid binding [GO:0003676]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; steroid binding [GO:0005496]; zinc ion binding [GO:0008270]" 0.88158 -0.10018 SYEDCASGIMEDSAIK 0 0 0 0 0 0 0 9.31506 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95741 CPNE6_HUMAN Copine-6 (Copine VI) (Neuronal-copine) (N-copine) CPNE6 Homo sapiens (Human) cell differentiation [GO:0030154]; cellular response to calcium ion [GO:0071277]; positive regulation of dendrite extension [GO:1903861]; postsynaptic actin cytoskeleton organization [GO:0098974] axon [GO:0030424]; clathrin-coated endocytic vesicle [GO:0045334]; dendrite [GO:0030425]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; perikaryon [GO:0043204]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; phosphatidylserine binding [GO:0001786] 0.9554 -1.5986 NYKSSGTVVLAQCTVEK 0 0 0 0 0 0 0 0 0 0 10.6788 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95744 PM2P2_HUMAN Putative postmeiotic segregation increased 2-like protein 2 (Postmeiotic segregation increased 2-like protein 14) (Postmeiotic segregation increased protein 4) (Putative postmeiotic segregation increased 2 pseudogene 2) PMS2P2 PMS2L14 PMS2L2 PMS4 Homo sapiens (Human) mismatch repair [GO:0006298] mismatch repair complex [GO:0032300] ATP hydrolysis activity [GO:0016887]; ATP-dependent DNA damage sensor activity [GO:0140664] 0.94914 -1.3782 ACFPFAFCR 0 11.7328 0 0 11.546 11.4477 0 11.5829 0 0 0 0 10.1803 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95749 GGPPS_HUMAN "Geranylgeranyl pyrophosphate synthase (GGPP synthase) (GGPPSase) (EC 2.5.1.-) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Farnesyltranstransferase) (EC 2.5.1.29) (Geranylgeranyl diphosphate synthase) (Geranyltranstransferase) (EC 2.5.1.10)" GGPS1 Homo sapiens (Human) farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; geranylgeranyl diphosphate biosynthetic process [GO:0033386]; isoprenoid biosynthetic process [GO:0008299]; isoprenoid metabolic process [GO:0006720] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; Z disc [GO:0030018] dimethylallyltranstransferase activity [GO:0004161]; farnesyltranstransferase activity [GO:0004311]; geranyltranstransferase activity [GO:0004337]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; prenyltransferase activity [GO:0004659] 0.96568 -2.3639 DDYANLHSK 0 0 0 0 0 0 0 0 0 9.44307 0 0 0 9.99563 0 0 0 11.2416 0 0 0 0 0 0 0 9.48127 0 O95750 FGF19_HUMAN Fibroblast growth factor 19 (FGF-19) FGF19 UNQ334/PRO533 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; bile acid and bile salt transport [GO:0015721]; cell differentiation [GO:0030154]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart development [GO:0007507]; negative regulation of bile acid biosynthetic process [GO:0070858]; negative regulation of gene expression [GO:0010629]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose import [GO:0046326]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein phosphorylation [GO:0001934]; regulation of cell migration [GO:0030334]; response to bacterium [GO:0009617]; response to ethanol [GO:0045471]; response to organic cyclic compound [GO:0014070] cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615] fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083] 0.91484 -0.78018 GQSAHSLLEIKAVALR 0 0 0 0 0 0 0 0 0 0 11.6994 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95757 HS74L_HUMAN Heat shock 70 kDa protein 4L (Heat shock 70-related protein APG-1) (Heat-shock protein family A member 4-like protein) (HSPA4-like protein) (Osmotic stress protein 94) HSPA4L APG1 OSP94 Homo sapiens (Human) protein folding [GO:0006457]; response to unfolded protein [GO:0006986] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP-dependent protein folding chaperone [GO:0140662] 0.8851 -0.3352 ALLRLYQECEK 13.3109 0 0 0 11.4646 11.3373 0 0 12.8259 0 10.2546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95759 TBCD8_HUMAN TBC1 domain family member 8 (AD 3) (Vascular Rab-GAP/TBC-containing protein) TBC1D8 VRP Homo sapiens (Human) activation of GTPase activity [GO:0090630]; blood circulation [GO:0008015]; positive regulation of cell population proliferation [GO:0008284] membrane [GO:0016020] GTPase activator activity [GO:0005096] 0.91984 -0.90652 INQYNLKTFEMSHQSQSELK 0 0 0 10.2808 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95777 LSM8_HUMAN U6 snRNA-associated Sm-like protein LSm8 LSM8 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]" Lsm2-8 complex [GO:0120115]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; precatalytic spliceosome [GO:0071011]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U6 snRNP [GO:0005688] RNA binding [GO:0003723]; U6 snRNA binding [GO:0017070] 0.88071 0.011227 GDNVAVIGEIDEETDSALDLGNIR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2928 0 0 0 0 0 0 0 0 0 0 0 0 0 O95782 AP2A1_HUMAN AP-2 complex subunit alpha-1 (100 kDa coated vesicle protein A) (Adaptor protein complex AP-2 subunit alpha-1) (Adaptor-related protein complex 2 subunit alpha-1) (Alpha-adaptin A) (Alpha1-adaptin) (Clathrin assembly protein complex 2 alpha-A large chain) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit) AP2A1 ADTAA CLAPA1 Homo sapiens (Human) clathrin-dependent endocytosis [GO:0072583]; endocytosis [GO:0006897]; Golgi to endosome transport [GO:0006895]; intracellular protein transport [GO:0006886]; negative regulation of hyaluronan biosynthetic process [GO:1900126]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; vesicle-mediated transport [GO:0016192] AP-2 adaptor complex [GO:0030122]; clathrin coat of trans-Golgi network vesicle [GO:0030130]; clathrin-coated endocytic vesicle [GO:0045334]; clathrin-coated endocytic vesicle membrane [GO:0030669]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endolysosome membrane [GO:0036020]; filopodium tip [GO:0032433]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794] clathrin adaptor activity [GO:0035615]; low-density lipoprotein particle receptor binding [GO:0050750]; protein kinase binding [GO:0019901] 0.96925 -3.2161 ALDGYSK 0 9.16812 0 0 10.1431 9.84227 0 0 0 0 8.81083 0 0 0 0 0 9.67052 9.68752 0 0 12.0794 0 10.1347 0 0 0 9.20865 O95786 RIGI_HUMAN Antiviral innate immune response receptor RIG-I (ATP-dependent RNA helicase DDX58) (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (RNA sensor RIG-I) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I) RIGI DDX58 Homo sapiens (Human) antiviral innate immune response [GO:0140374]; cellular response to exogenous dsRNA [GO:0071360]; cytosolic pattern recognition receptor signaling pathway [GO:0002753]; defense response to virus [GO:0051607]; detection of virus [GO:0009597]; gene expression [GO:0010467]; innate immune response [GO:0045087]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of gene expression [GO:0010628]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of myeloid dendritic cell cytokine production [GO:0002735]; positive regulation of response to cytokine stimulus [GO:0060760]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell migration [GO:0030334]; regulation of type III interferon production [GO:0034344]; response to exogenous dsRNA [GO:0043330]; response to virus [GO:0009615]; RIG-I signaling pathway [GO:0039529] actin cytoskeleton [GO:0015629]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]; ruffle membrane [GO:0032587] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; double-stranded DNA binding [GO:0003690]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; molecular function activator activity [GO:0140677]; pattern recognition receptor activity [GO:0038187]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activator activity [GO:0097027]; zinc ion binding [GO:0008270] 0.9693 -6.0488 EQINMYKEK 0 0 0 0 0 0 0 0 9.19044 0 0 0 0 0 0 0 0 0 8.9484 0 0 0 0 9.78203 0 0 11.0915 O95789 ZMYM6_HUMAN Zinc finger MYM-type protein 6 (Transposon-derived Buster2 transposase-like protein) (Zinc finger protein 258) ZMYM6 Buster2 KIAA1353 ZNF258 Homo sapiens (Human) cytoskeleton organization [GO:0007010]; regulation of cell morphogenesis [GO:0022604] nucleus [GO:0005634] DNA binding [GO:0003677]; zinc ion binding [GO:0008270] 0.96216 -2.5095 AKTAVTELPSAR 0 10.2416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3422 9.85448 0 0 0 11.0963 0 0 11.11 O95793 STAU1_HUMAN Double-stranded RNA-binding protein Staufen homolog 1 STAU1 STAU Homo sapiens (Human) anterograde dendritic transport of messenger ribonucleoprotein complex [GO:0098964]; cellular response to oxidative stress [GO:0034599]; modification of postsynaptic structure [GO:0099010]; positive regulation by virus of viral protein levels in host cell [GO:0046726]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of viral genome replication [GO:0045070]; protein localization to synapse [GO:0035418] cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; microtubule associated complex [GO:0005875]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791] double-stranded RNA binding [GO:0003725]; protein phosphatase 1 binding [GO:0008157]; RNA binding [GO:0003723] 0.88353 -0.1759 GGAYPPR 0 9.22142 0 0 0 0 0 0 0 0 0 0 0 0 0 11.122 0 0 0 0 0 0 0 0 0 0 0 O95800 GPR75_HUMAN Probable G-protein coupled receptor 75 GPR75 Homo sapiens (Human) chemokine-mediated signaling pathway [GO:0070098]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of neuron death [GO:1901214] plasma membrane [GO:0005886] C-C chemokine receptor activity [GO:0016493]; G protein-coupled receptor activity [GO:0004930] 0.95395 -1.5167 GNLEVNRNK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.30927 0 0 0 0 0 0 0 0 0 0 0 0 0 O95819 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase) MAP4K4 HGK KIAA0687 NIK Homo sapiens (Human) intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-matrix adhesion [GO:0001953]; neuron projection morphogenesis [GO:0048812]; positive regulation of ARF protein signal transduction [GO:0032014]; positive regulation of cell migration [GO:0030335]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of focal adhesion disassembly [GO:0120183]; positive regulation of GTPase activity [GO:0043547]; positive regulation of keratinocyte migration [GO:0051549]; protein phosphorylation [GO:0006468]; regulation of JNK cascade [GO:0046328]; regulation of MAPK cascade [GO:0043408] cytoplasm [GO:0005737]; focal adhesion [GO:0005925] ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; microtubule binding [GO:0008017]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.95556 -1.5847 DFLRLQQENK 13.9884 0 0 9.74942 0 9.04207 12.4061 10.8344 0 0 11.1201 0 0 0 0 0 0 0 9.87666 0 0 0 10.9806 0 10.2009 0 0 O95822 DCMC_HUMAN "Malonyl-CoA decarboxylase, mitochondrial (MCD) (EC 4.1.1.9)" MLYCD Homo sapiens (Human) acetyl-CoA biosynthetic process [GO:0006085]; acyl-CoA metabolic process [GO:0006637]; fatty acid biosynthetic process [GO:0006633]; fatty acid oxidation [GO:0019395]; malonyl-CoA catabolic process [GO:2001294]; positive regulation of fatty acid oxidation [GO:0046321]; regulation of fatty acid beta-oxidation [GO:0031998]; regulation of glucose metabolic process [GO:0010906]; response to ischemia [GO:0002931] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777] identical protein binding [GO:0042802]; malonyl-CoA decarboxylase activity [GO:0050080] 0.88472 -0.23609 GLFHHISK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7821 0 0 0 0 0 0 0 O95832 CLD1_HUMAN Claudin-1 (Senescence-associated epithelial membrane protein) CLDN1 CLD1 SEMP1 UNQ481/PRO944 Homo sapiens (Human) aging [GO:0007568]; bicellular tight junction assembly [GO:0070830]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; cell junction maintenance [GO:0034331]; cell-cell junction organization [GO:0045216]; cellular response to butyrate [GO:1903545]; cellular response to lead ion [GO:0071284]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to type II interferon [GO:0071346]; establishment of blood-nerve barrier [GO:0008065]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of skin barrier [GO:0061436]; hyperosmotic salinity response [GO:0042538]; liver regeneration [GO:0097421]; maintenance of blood-brain barrier [GO:0035633]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of wound healing [GO:0090303]; protein complex oligomerization [GO:0051259]; response to dexamethasone [GO:0071548]; response to ethanol [GO:0045471]; response to interleukin-18 [GO:0070673]; response to lipopolysaccharide [GO:0032496]; response to toxic substance [GO:0009636]; xenobiotic transport across blood-nerve barrier [GO:0061772] apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; lateral plasma membrane [GO:0016328]; membrane [GO:0016020]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; tight junction [GO:0070160] identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; virus receptor activity [GO:0001618] 0.91282 -0.75289 CMKCLEDDEVQK 0 0 0 0 11.8151 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95833 CLIC3_HUMAN Chloride intracellular channel protein 3 CLIC3 Homo sapiens (Human) chloride transport [GO:0006821]; regulation of monoatomic ion transmembrane transport [GO:0034765]; signal transduction [GO:0007165] chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nuclear body [GO:0016604]; nucleus [GO:0005634] chloride channel activity [GO:0005254]; voltage-gated monoatomic ion channel activity [GO:0005244] 0.94608 -1.3441 GVRRYLDSAMQEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2244 0 0 0 0 0 0 0 O95834 EMAL2_HUMAN Echinoderm microtubule-associated protein-like 2 (EMAP-2) (HuEMAP-2) EML2 EMAP2 EMAPL2 Homo sapiens (Human) microtubule cytoskeleton organization [GO:0000226]; negative regulation of microtubule polymerization [GO:0031115]; regulation of microtubule nucleation [GO:0010968]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; spindle [GO:0005819] ionotropic glutamate receptor binding [GO:0035255]; microtubule binding [GO:0008017]; protein self-association [GO:0043621]; tubulin binding [GO:0015631] 0.88939 -0.42277 RQGLFEK 9.00753 8.98257 8.81237 9.52781 0 0 9.98513 9.95412 9.8921 0 8.39665 0 8.41346 0 0 10.187 10.6611 0 9.42448 10.1909 10.0647 11.0782 11.1544 0 0 9.71371 9.55261 O95837 GNA14_HUMAN Guanine nucleotide-binding protein subunit alpha-14 (G alpha-14) (G-protein subunit alpha-14) GNA14 Homo sapiens (Human) action potential [GO:0001508]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; signal transduction [GO:0007165] extracellular exosome [GO:0070062]; heterotrimeric G-protein complex [GO:0005834]; plasma membrane [GO:0005886] G protein-coupled receptor binding [GO:0001664]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872] 0.88397 -0.2548 ELKLLLLGTGESGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0293 0 0 10.4804 0 0 0 0 O95841 ANGL1_HUMAN Angiopoietin-related protein 1 (Angiopoietin-3) (ANG-3) (Angiopoietin-like protein 1) ANGPTL1 ANG3 ANGPT3 ARP1 PSEC0154 UNQ162/PRO188 Homo sapiens (Human) transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615] signaling receptor binding [GO:0005102] 0.91524 -0.7902 ILNVTTEMLKMATR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1948 0 0 0 0 0 0 0 0 0 0 0 0 0 O95847 UCP4_HUMAN Mitochondrial uncoupling protein 4 (UCP 4) (Solute carrier family 25 member 27) SLC25A27 UCP4 UNQ772/PRO1566 Homo sapiens (Human) response to cold [GO:0009409] mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739] transmembrane transporter activity [GO:0022857] 0.16271 1.0043 MSVPEEEER 0 9.75839 9.77136 0 0 0 0 9.96212 10.0242 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95848 NUD14_HUMAN Uridine diphosphate glucose pyrophosphatase NUDT14 (UDPG pyrophosphatase) (UGPPase) (EC 3.6.1.45) (Nucleoside diphosphate-linked moiety X motif 14) (Nudix motif 14) NUDT14 UGPP Homo sapiens (Human) nucleoside phosphate metabolic process [GO:0006753]; protein N-linked glycosylation via asparagine [GO:0018279]; ribose phosphate metabolic process [GO:0019693] cytosol [GO:0005829] ADP-ribose diphosphatase activity [GO:0047631]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; UDP-sugar diphosphatase activity [GO:0008768] 0.42337 0.66638 QFRPAVYAGEVERR 0 0 0 0 0 10.6754 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95861 BPNT1_HUMAN "3'(2'),5'-bisphosphate nucleotidase 1 (EC 3.1.3.7) (Bisphosphate 3'-nucleotidase 1) (PAP-inositol 1,4-phosphatase) (PIP)" BPNT1 Homo sapiens (Human) 3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; nervous system development [GO:0007399]; nucleobase-containing compound metabolic process [GO:0006139]; phosphatidylinositol phosphate biosynthetic process [GO:0046854] cytosol [GO:0005829] "3'(2'),5'-bisphosphate nucleotidase activity [GO:0008441]; metal ion binding [GO:0046872]" 0.010204 1.9545 IIQLIEGK 8.73589 9.67389 0 0 0 0 0 0 0 0 0 9.00282 9.37145 9.34192 0 0 0 0 0 0 0 0 0 0 0 0 10.0896 O95864 FADS2_HUMAN Acyl-CoA 6-desaturase (EC 1.14.19.3) (Delta(6) fatty acid desaturase) (D6D) (Delta(6) desaturase) (Delta-6 desaturase) (Fatty acid desaturase 2) FADS2 Homo sapiens (Human) alpha-linolenic acid metabolic process [GO:0036109]; linoleic acid metabolic process [GO:0043651]; lipid metabolic process [GO:0006629]; unsaturated fatty acid biosynthetic process [GO:0006636] endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886] "linoleoyl-CoA desaturase activity [GO:0016213]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]; stearoyl-CoA 9-desaturase activity [GO:0004768]" 0.92432 -1.0238 LWLDAYLHK 0 0 0 0 0 0 0 0 0 0 0 0 9.96838 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95866 G6B_HUMAN Megakaryocyte and platelet inhibitory receptor G6b (Protein G6b) MPIG6B C6orf25 G6B G6B-B Homo sapiens (Human) blood coagulation [GO:0007596]; erythrocyte differentiation [GO:0030218]; integrin-mediated signaling pathway [GO:0007229]; megakaryocyte development [GO:0035855]; megakaryocyte differentiation [GO:0030219]; negative regulation of signal transduction [GO:0009968]; platelet formation [GO:0030220] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] heparin binding [GO:0008201] 0.87049 0.065427 LSTADPADASTIYAVVV 0 0 0 0 0 9.89295 11.2932 0 0 0 0 12.0799 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95876 FRITZ_HUMAN WD repeat-containing and planar cell polarity effector protein fritz homolog (hFRTZ) (Bardet-Biedl syndrome 15 protein) (WD repeat-containing and planar cell polarity effector protein) WDPCP BBS15 C2orf86 FRITZ Homo sapiens (Human) auditory receptor cell morphogenesis [GO:0002093]; camera-type eye development [GO:0043010]; cilium assembly [GO:0060271]; cilium organization [GO:0044782]; circulatory system development [GO:0072359]; digestive system development [GO:0055123]; embryonic digit morphogenesis [GO:0042733]; establishment of planar polarity [GO:0001736]; establishment of protein localization [GO:0045184]; intraciliary transport [GO:0042073]; kidney development [GO:0001822]; nervous system development [GO:0007399]; neural tube development [GO:0021915]; podocyte cell migration [GO:0090521]; regulation of cilium assembly [GO:1902017]; regulation of embryonic cell shape [GO:0016476]; regulation of establishment of cell polarity [GO:2000114]; regulation of fibroblast migration [GO:0010762]; regulation of focal adhesion assembly [GO:0051893]; regulation of protein localization [GO:0032880]; regulation of ruffle assembly [GO:1900027]; respiratory system development [GO:0060541]; roof of mouth development [GO:0060021]; septin cytoskeleton organization [GO:0032185]; smoothened signaling pathway [GO:0007224]; tongue morphogenesis [GO:0043587] axonemal basal plate [GO:0097541]; axoneme [GO:0005930]; cilium [GO:0005929]; plasma membrane [GO:0005886] 0.96165 -2.0495 FERGPLGVLLFK 0 0 0 0 0 0 9.53632 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95886 DLGP3_HUMAN Disks large-associated protein 3 (DAP-3) (PSD-95/SAP90-binding protein 3) (SAP90/PSD-95-associated protein 3) (SAPAP3) DLGAP3 DAP3 Homo sapiens (Human) modification of synaptic structure [GO:0099563]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; signaling [GO:0023052] cholinergic synapse [GO:0098981]; glutamatergic synapse [GO:0098978]; neuromuscular junction [GO:0031594]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic specialization [GO:0099572] amyloid-beta binding [GO:0001540]; molecular adaptor activity [GO:0060090] 0.96966 -3.2628 IRHLVHSVQK 0 0 0 0 0 0 0 0 0 0 0 0 8.11082 0 0 0 0 0 0 0 0 0 0 9.90418 0 0 0 O95900 TRUB2_HUMAN "Pseudouridylate synthase TRUB2, mitochondrial (EC 5.4.99.-) (TruB pseudouridine synthase homolog 2) (tRNA pseudouridine 55 synthase TRUB2) (Psi55 synthase TRUB2) (EC 5.4.99.25)" TRUB2 Homo sapiens (Human) mRNA processing [GO:0006397]; mRNA pseudouridine synthesis [GO:1990481]; positive regulation of mitochondrial translation [GO:0070131]; tRNA processing [GO:0008033] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ribonucleoprotein granule [GO:0035770] pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723] 0.96736 -3.7031 LVEKTTYDHVTREK 0 0 0 0 10.7329 9.44686 0 0 0 0 10.0518 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95926 SYF2_HUMAN Pre-mRNA-splicing factor SYF2 (CCNDBP1-interactor) (p29) SYF2 CBPIN GCIPIP Homo sapiens (Human) "embryonic organ development [GO:0048568]; gastrulation [GO:0007369]; in utero embryonic development [GO:0001701]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of cell population proliferation [GO:0008284]" catalytic step 2 spliceosome [GO:0071013]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; post-mRNA release spliceosomal complex [GO:0071014]; Prp19 complex [GO:0000974]; U2-type catalytic step 2 spliceosome [GO:0071007] RNA binding [GO:0003723] 0.78625 0.25788 LLEISAEDAER 0 10.2002 10.0186 0 0 0 0 0 0 0 10.3545 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95932 TGM3L_HUMAN Protein-glutamine gamma-glutamyltransferase 6 (EC 2.3.2.13) (Transglutaminase Y) (TGY) (TGase Y) (Transglutaminase-3-like) (TGase-3-like) (Transglutaminase-6) (TG6) (TGase-6) TGM6 TGM3L Homo sapiens (Human) peptide cross-linking [GO:0018149] cytoplasm [GO:0005737] metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810] 0.96924 -3.0368 AVGSDSR 0 10.1312 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5596 0 8.96691 O95947 TBX6_HUMAN T-box transcription factor TBX6 (T-box protein 6) TBX6 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; cell fate specification [GO:0001708]; heart looping [GO:0001947]; mesoderm development [GO:0007498]; mesodermal cell fate specification [GO:0007501]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron maturation [GO:0014043]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction involved in regulation of gene expression [GO:0023019]; somite rostral/caudal axis specification [GO:0032525]; vasculogenesis [GO:0001570] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.88627 -0.33865 QPVSFHRVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.326 0 O95954 FTCD_HUMAN Formimidoyltransferase-cyclodeaminase (Formiminotransferase-cyclodeaminase) (FTCD) (LCHC1) [Includes: Glutamate formimidoyltransferase (EC 2.1.2.5) (Glutamate formiminotransferase) (Glutamate formyltransferase); Formimidoyltetrahydrofolate cyclodeaminase (EC 4.3.1.4) (Formiminotetrahydrofolate cyclodeaminase)] FTCD Homo sapiens (Human) cytoskeleton organization [GO:0007010]; folic acid-containing compound metabolic process [GO:0006760]; histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557] centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; smooth endoplasmic reticulum membrane [GO:0030868] folic acid binding [GO:0005542]; formimidoyltetrahydrofolate cyclodeaminase activity [GO:0030412]; glutamate formimidoyltransferase activity [GO:0030409]; microtubule binding [GO:0008017] 0.13298 1.0606 AGEYEALPKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.3102 0 0 0 0 10.6254 0 0 O95967 FBLN4_HUMAN EGF-containing fibulin-like extracellular matrix protein 2 (Fibulin-4) (FIBL-4) (Protein UPH1) EFEMP2 FBLN4 UNQ200/PRO226 Homo sapiens (Human) aorta development [GO:0035904]; aorta smooth muscle tissue morphogenesis [GO:0060414]; elastic fiber assembly [GO:0048251]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; positive regulation of aortic smooth muscle cell differentiation [GO:1904831]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of smooth muscle cell-matrix adhesion [GO:1905609]; regulation of collagen fibril organization [GO:1904026]; vascular associated smooth muscle cell development [GO:0097084] basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; elastic fiber [GO:0071953]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular vesicle [GO:1903561]; microfibril [GO:0001527] calcium ion binding [GO:0005509]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; protein homodimerization activity [GO:0042803] 0.86943 0.044123 LTVFVGAYTF 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.85479 O95970 LGI1_HUMAN Leucine-rich glioma-inactivated protein 1 (Epitempin-1) LGI1 EPT UNQ775/PRO1569 Homo sapiens (Human) axon guidance [GO:0007411]; nervous system development [GO:0007399]; neuron projection development [GO:0031175]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; positive regulation of cell growth [GO:0030307]; positive regulation of synaptic transmission [GO:0050806] axon initial segment [GO:0043194]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; synaptic cleft [GO:0043083] signaling receptor binding [GO:0005102] 0.86344 0.089583 DFDCIITEFAK 0 0 0 0 0 0 11.2106 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95972 BMP15_HUMAN Bone morphogenetic protein 15 (BMP-15) (Growth/differentiation factor 9B) (GDF-9B) BMP15 GDF9B Homo sapiens (Human) BMP signaling pathway [GO:0030509]; female gamete generation [GO:0007292]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; SMAD protein signal transduction [GO:0060395] endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615] cytokine activity [GO:0005125]; growth factor activity [GO:0008083] 0.84968 0.15826 FNLSCHVEPWVQK 0 0 0 0 0 0 0 0 8.82295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95980 RECK_HUMAN Reversion-inducing cysteine-rich protein with Kazal motifs (hRECK) (Suppressor of tumorigenicity 15 protein) RECK ST15 Homo sapiens (Human) blood vessel maturation [GO:0001955]; embryo implantation [GO:0007566]; embryonic forelimb morphogenesis [GO:0035115]; extracellular matrix organization [GO:0030198]; negative regulation of cell migration [GO:0030336]; negative regulation of metalloendopeptidase activity [GO:1904684]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; regulation of angiogenesis [GO:0045765]; regulation of establishment of blood-brain barrier [GO:0090210]; sprouting angiogenesis [GO:0002040] extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; Wnt signalosome [GO:1990909] coreceptor activity involved in canonical Wnt signaling pathway [GO:1904928]; endopeptidase inhibitor activity [GO:0004866]; metalloendopeptidase inhibitor activity [GO:0008191]; serine-type endopeptidase inhibitor activity [GO:0004867]; Wnt-protein binding [GO:0017147] 0.9106 -0.74705 ANTSTCRELCTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1153 0 0 0 0 0 0 0 0 0 0 0 O95983 MBD3_HUMAN Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3) MBD3 Homo sapiens (Human) aging [GO:0007568]; brain development [GO:0007420]; chromatin remodeling [GO:0006338]; DNA methylation-dependent heterochromatin formation [GO:0006346]; embryonic organ development [GO:0048568]; heart development [GO:0007507]; histone acetylation [GO:0016573]; histone deacetylation [GO:0016575]; in utero embryonic development [GO:0001701]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cell fate specification [GO:0042659]; regulation of DNA methylation [GO:0044030]; regulation of stem cell differentiation [GO:2000736]; response to estradiol [GO:0032355]; response to nutrient levels [GO:0031667]; tissue development [GO:0009888] chromatin [GO:0000785]; cytoplasm [GO:0005737]; heterochromatin [GO:0000792]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NuRD complex [GO:0016581]; protein-containing complex [GO:0032991] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; methyl-CpG binding [GO:0008327] 0.83636 0.19447 YDSSNQVK 8.32962 0 8.23606 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95985 TOP3B_HUMAN DNA topoisomerase 3-beta-1 (EC 5.6.2.1) (DNA topoisomerase III beta-1) TOP3B TOP3B1 Homo sapiens (Human) chromosome segregation [GO:0007059]; DNA topological change [GO:0006265] condensed chromosome [GO:0000793]; DNA topoisomerase III-beta-TDRD3 complex [GO:0140225]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA topoisomerase activity [GO:0003916]; DNA topoisomerase type I (single strand cut, ATP-independent) activity [GO:0003917]; RNA binding [GO:0003723]" 0.96379 -2.6502 CGKCHRFMK 0 0 10.3761 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3701 0 O95990 F107A_HUMAN Actin-associated protein FAM107A (Down-regulated in renal cell carcinoma 1) (Protein TU3A) FAM107A DRR1 TU3A Homo sapiens (Human) actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; cell cycle [GO:0007049]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to nutrient levels [GO:0031669]; cognition [GO:0050890]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of long-term synaptic potentiation [GO:1900272]; positive regulation of cell migration [GO:0030335]; positive regulation of protein ubiquitination [GO:0031398]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell growth [GO:0001558]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of protein stability [GO:0031647] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; focal adhesion [GO:0005925]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; ruffle membrane [GO:0032587]; stress fiber [GO:0001725]; synapse [GO:0045202] actin binding [GO:0003779] 0.96171 -2.076 EEDHAPEFIKVR 10.3385 0 0 0 0 0 0 0 10.2241 0 0 9.29964 0 0 0 0 0 0 10.3245 0 0 0 10.1993 11.1606 0 11.9718 0 O95994 AGR2_HUMAN Anterior gradient protein 2 homolog (AG-2) (hAG-2) (HPC8) (Secreted cement gland protein XAG-2 homolog) AGR2 AG2 UNQ515/PRO1030 Homo sapiens (Human) digestive tract morphogenesis [GO:0048546]; inflammatory response [GO:0006954]; lung goblet cell differentiation [GO:0060480]; mucus secretion [GO:0070254]; negative regulation of cell death [GO:0060548]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of developmental growth [GO:0048639]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of gene expression [GO:0010628]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of PERK-mediated unfolded protein response [GO:1903899]; positive regulation of protein localization to plasma membrane [GO:1903078] endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615] dystroglycan binding [GO:0002162]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802] 0 24.37 IMFVDPSLTVR 0 0 0 0 0 0 10.3089 10.4027 10.1924 0 0 0 0 0 0 0 0 0 13.3266 12.2994 13.194 13.4332 13.0887 12.7512 14.681 14.368 13.8141 O95995 DRC4_HUMAN Dynein regulatory complex subunit 4 (Growth arrest-specific protein 11) (GAS-11) (Growth arrest-specific protein 8) (GAS-8) GAS8 DRC4 GAS11 Homo sapiens (Human) axoneme assembly [GO:0035082]; brain development [GO:0007420]; cilium movement involved in cell motility [GO:0060294]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of protein localization to cilium [GO:1903566]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization [GO:0008104]; regulation of microtubule binding [GO:1904526] axoneme [GO:0005930]; ciliary basal body [GO:0036064]; cilium [GO:0005929]; cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; microtubule [GO:0005874]; motile cilium [GO:0031514]; plasma membrane [GO:0005886]; sperm flagellum [GO:0036126] microtubule binding [GO:0008017]; small GTPase binding [GO:0031267] 0.9214 -1.1048 DKQILLCTK 0 0 0 0 0 0 0 0 0 0 0 9.09766 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O95996 APCL_HUMAN Adenomatous polyposis coli protein 2 (Adenomatous polyposis coli protein-like) (APC-like) APC2 APCL Homo sapiens (Human) activation of GTPase activity [GO:0090630]; cell fate specification [GO:0001708]; cell migration [GO:0016477]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of microtubule depolymerization [GO:0007026]; nervous system development [GO:0007399]; pattern specification process [GO:0007389]; positive regulation of protein catabolic process [GO:0045732]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell differentiation [GO:0045595]; Wnt signaling pathway [GO:0016055] actin filament [GO:0005884]; beta-catenin destruction complex [GO:0030877]; catenin complex [GO:0016342]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intercellular bridge [GO:0045171]; lamellipodium membrane [GO:0031258]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794] beta-catenin binding [GO:0008013]; gamma-catenin binding [GO:0045295]; microtubule binding [GO:0008017] 0.969 -5.8264 ALEAELDAR 0 0 8.69968 0 0 0 0 0 8.80281 8.68647 0 9.59307 11.63 0 0 9.74858 0 0 0 10.4279 10.8797 0 8.30606 0 9.21318 10.9803 0 O95998 I18BP_HUMAN Interleukin-18-binding protein (IL-18BP) (Tadekinig-alfa) IL18BP Homo sapiens (Human) cellular response to hydrogen peroxide [GO:0070301]; cellular response to tumor necrosis factor [GO:0071356]; response to lipopolysaccharide [GO:0032496]; T-helper 1 type immune response [GO:0042088] extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615] interleukin-18 binding [GO:0042007]; receptor antagonist activity [GO:0048019] 0.95103 -1.3838 LWEGSTSR 0 8.37069 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O96005 CLPT1_HUMAN Putative lipid scramblase CLPTM1 (Cleft lip and palate transmembrane protein 1) CLPTM1 Homo sapiens (Human) cell differentiation [GO:0030154]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; regulation of T cell differentiation in thymus [GO:0033081] endomembrane system [GO:0012505]; external side of plasma membrane [GO:0009897]; GABA-ergic synapse [GO:0098982]; membrane [GO:0016020]; plasma membrane [GO:0005886] GABA receptor binding [GO:0050811] 0.88259 -0.077458 LSFKDKSTYIESSTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.21369 0 O96006 ZBED1_HUMAN E3 SUMO-protein ligase ZBED1 (EC 2.3.2.-) (DNA replication-related element-binding factor) (Putative Ac-like transposable element) (Zinc finger BED domain-containing protein 1) (dREF homolog) ZBED1 ALTE DREF hDREF KIAA0785 TRAMP Homo sapiens (Human) negative regulation by host of viral genome replication [GO:0044828]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autosumoylation [GO:1990466]; protein sumoylation [GO:0016925]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] centrosome [GO:0005813]; chromatin [GO:0000785]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; SUMO ligase activity [GO:0061665]; SUMO transferase activity [GO:0019789]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]" 0.28159 0.83111 LFGSAANVVSAK 0 0 0 0 0 0 0 0 0 0 0 0 0 17.0437 17.0938 0 0 0 0 0 0 0 0 12.3652 11.4972 0 0 O96009 NAPSA_HUMAN Napsin-A (EC 3.4.23.-) (Aspartyl protease 4) (ASP4) (Asp 4) (Napsin-1) (TA01/TA02) NAPSA NAP1 NAPA Homo sapiens (Human) membrane protein proteolysis [GO:0033619]; proteolysis [GO:0006508]; surfactant homeostasis [GO:0043129] alveolar lamellar body [GO:0097208]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body lumen [GO:0097486] aspartic-type endopeptidase activity [GO:0004190]; endopeptidase activity [GO:0004175]; peptidase activity [GO:0008233] 0.30423 0.80464 MSPPPLLQPLLLLLPLLNVEPSGATLIR 0 9.23537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.86414 0 0 0 0 0 O96011 PX11B_HUMAN Peroxisomal membrane protein 11B (Peroxin-11B) (Peroxisomal biogenesis factor 11B) (Protein PEX11 homolog beta) (PEX11-beta) PEX11B Homo sapiens (Human) peroxisome fission [GO:0016559]; peroxisome organization [GO:0007031]; regulation of peroxisome size [GO:0044375]; signal transduction [GO:0007165] cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991] identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803] 0.95893 -1.7687 DAWVRFSAQSQAR 0 0 0 0 0 8.93062 0 0 0 0 0 0 0 0 0 0 0 10.4976 0 0 0 9.32186 0 0 0 0 0 O96013 PAK4_HUMAN Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4) PAK4 KIAA1142 Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell migration [GO:0016477]; cellular response to organic cyclic compound [GO:0071407]; cytoskeleton organization [GO:0007010]; dendritic spine development [GO:0060996]; intracellular signal transduction [GO:0035556]; negative regulation of endothelial cell apoptotic process [GO:2000352]; positive regulation of angiogenesis [GO:0045766]; protein phosphorylation [GO:0006468]; regulation of cell growth [GO:0001558]; regulation of MAPK cascade [GO:0043408]; signal transduction [GO:0007165] adherens junction [GO:0005912]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794] ATP binding [GO:0005524]; cadherin binding involved in cell-cell adhesion [GO:0098641]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.92263 -1.0844 NLHKVSPSLK 0 0 0 0 0 0 0 0 0 10.4878 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 O96020 CCNE2_HUMAN G1/S-specific cyclin-E2 CCNE2 Homo sapiens (Human) cell division [GO:0051301]; DNA replication initiation [GO:0006270]; G1/S transition of mitotic cell cycle [GO:0000082]; homologous chromosome pairing at meiosis [GO:0007129]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of protein localization [GO:0032880]; telomere maintenance [GO:0000723] centrosome [GO:0005813]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; protein kinase binding [GO:0019901] 0.92447 -1.0241 EIGTSDFSR 0 0 9.77737 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.45156 0 0 0 O96028 NSD2_HUMAN Histone-lysine N-methyltransferase NSD2 (EC 2.1.1.357) (Multiple myeloma SET domain-containing protein) (MMSET) (Nuclear SET domain-containing protein 2) (Protein trithorax-5) (Wolf-Hirschhorn syndrome candidate 1 protein) NSD2 KIAA1090 MMSET TRX5 WHSC1 Homo sapiens (Human) atrial septum primum morphogenesis [GO:0003289]; atrial septum secundum morphogenesis [GO:0003290]; bone development [GO:0060348]; double-strand break repair [GO:0006302]; membranous septum morphogenesis [GO:0003149]; methylation [GO:0032259]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of isotype switching to IgA isotypes [GO:0048298]; regulation of DNA-templated transcription [GO:0006355]; regulation of double-strand break repair via nonhomologous end joining [GO:2001032]; regulation of establishment of protein localization [GO:0070201] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; histone H3K36 dimethyltransferase activity [GO:0140954]; histone H3K36 methyltransferase activity [GO:0046975]; histone H3K36 trimethyltransferase activity [GO:0140955]; histone H4K20 methyltransferase activity [GO:0042799]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565] 0.96708 -2.3172 DRIIDAGPKGNYSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6284 0 0 0 0 0 P00167 CYB5_HUMAN Cytochrome b5 (Microsomal cytochrome b5 type A) (MCB5) CYB5A CYB5 Homo sapiens (Human) cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741] cytochrome-c oxidase activity [GO:0004129]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872] 0.87158 0.029376 TFIIGELHPDDRPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.88533 0 0 0 0 0 0 0 0 0 0 0 0 P00338 LDHA_HUMAN L-lactate dehydrogenase A chain (LDH-A) (EC 1.1.1.27) (Cell proliferation-inducing gene 19 protein) (LDH muscle subunit) (LDH-M) (Renal carcinoma antigen NY-REN-59) LDHA PIG19 Homo sapiens (Human) glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; pyruvate metabolic process [GO:0006090]; substantia nigra development [GO:0021762] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; oxidoreductase complex [GO:1990204] cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; L-lactate dehydrogenase activity [GO:0004459] 0 25.56 DYNVTANSK 11.5214 11.8838 10.9156 0 0 0 11.9707 12.0928 12.1761 13.0436 12.9054 12.7212 11.4322 11.5046 11.8544 12.0375 11.8892 11.0721 9.58637 11.1545 10.678 10.0238 9.81393 0 10.4149 10.0137 11.8341 P00352 AL1A1_HUMAN "Aldehyde dehydrogenase 1A1 (EC 1.2.1.19) (EC 1.2.1.28) (EC 1.2.1.3) (EC 1.2.1.36) (3-deoxyglucosone dehydrogenase) (ALDH-E1) (ALHDII) (Aldehyde dehydrogenase family 1 member A1) (Aldehyde dehydrogenase, cytosolic) (Retinal dehydrogenase 1) (RALDH 1) (RalDH1)" ALDH1A1 ALDC ALDH1 PUMB1 Homo sapiens (Human) cellular aldehyde metabolic process [GO:0006081]; cellular detoxification of aldehyde [GO:0110095]; fructosamine catabolic process [GO:0030392]; gamma-aminobutyric acid biosynthetic process [GO:0009449]; maintenance of lens transparency [GO:0036438]; negative regulation of cold-induced thermogenesis [GO:0120163]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572] axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; synapse [GO:0045202] 3-deoxyglucosone dehydrogenase activity [GO:0106373]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; androgen binding [GO:0005497]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; GTPase activator activity [GO:0005096]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758] 0.94804 -1.3623 GRLLYKLADLIER 0 0 0 0 0 0 0 8.88185 8.83083 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P00367 DHE3_HUMAN "Glutamate dehydrogenase 1, mitochondrial (GDH 1) (EC 1.4.1.3)" GLUD1 GLUD Homo sapiens (Human) glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350] cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]; protein homodimerization activity [GO:0042803] 0.96892 -3.3757 IIAEGANGPTTPEADKIFLER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9301 0 0 9.96391 10.1165 0 0 0 11.0036 11.4341 P00387 NB5R3_HUMAN NADH-cytochrome b5 reductase 3 (B5R) (Cytochrome b5 reductase) (EC 1.6.2.2) (Diaphorase-1) CYB5R3 DIA1 Homo sapiens (Human) blood circulation [GO:0008015]; cholesterol biosynthetic process [GO:0006695]; nitric oxide biosynthetic process [GO:0006809] azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; lipid droplet [GO:0005811]; membrane [GO:0016020]; mitochondrial membrane [GO:0031966]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nitric-oxide synthase complex [GO:1903958] "cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]" 0.10615 1.1541 STPAITLESPDIKYPLR 0 0 0 0 0 0 0 0 0 0 0 0 9.4872 9.61198 9.42221 0 10.4673 9.23688 0 0 0 0 0 0 0 9.83197 0 P00390 GSHR_HUMAN "Glutathione reductase, mitochondrial (GR) (GRase) (EC 1.8.1.7)" GSR GLUR GRD1 Homo sapiens (Human) cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749] cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase (NADPH) activity [GO:0004362]; NADP binding [GO:0050661] 0 2.9057 ALLTPVAIAAGR 0 0 0 0 0 0 0 0 0 0 10.1141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P00441 SODC_HUMAN Superoxide dismutase [Cu-Zn] (EC 1.15.1.1) (Superoxide dismutase 1) (hSod1) SOD1 Homo sapiens (Human) aging [GO:0007568]; anterograde axonal transport [GO:0008089]; apoptotic process [GO:0006915]; auditory receptor cell stereocilium organization [GO:0060088]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to potassium ion [GO:0035865]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; intracellular iron ion homeostasis [GO:0006879]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of developmental process [GO:0051093]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of reproductive process [GO:2000242]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular associated smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antibiotic [GO:0046677]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to nutrient levels [GO:0031667]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; response to xenobiotic stimulus [GO:0009410]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226] axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991] copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; ion binding [GO:0043167]; protein phosphatase 2B binding [GO:0030346]; protein-folding chaperone binding [GO:0051087]; small GTPase binding [GO:0031267]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270] 0.0062305 2.7207 GDGPVQGIINFEQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.6271 0 9.85098 9.4071 9.27387 9.29666 0 9.27775 9.61581 10.6777 11.3534 10.6205 P00450 CERU_HUMAN Ceruloplasmin (EC 1.16.3.1) (Ferroxidase) CP Homo sapiens (Human) copper ion transport [GO:0006825]; intracellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826] blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886] copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity [GO:0016491]; protein-folding chaperone binding [GO:0051087] 0.86898 0.044658 DNEDFQESNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.15201 0 0 0 P00451 FA8_HUMAN "Coagulation factor VIII (Antihemophilic factor) (AHF) (Procoagulant component) [Cleaved into: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain]" F8 F8C Homo sapiens (Human) "acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]" COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; serine-type endopeptidase complex [GO:1905370] copper ion binding [GO:0005507]; oxidoreductase activity [GO:0016491] 0.91408 -0.78267 FDDDNSPSFIQIR 13.9535 11.4721 13.5818 0 0 0 0 11.0373 0 0 8.92739 8.5494 10.1487 10.4994 10.5018 10.3385 10.4855 0 0 0 0 0 0 0 10.6942 0 0 P00480 OTC_HUMAN "Ornithine transcarbamylase, mitochondrial (OTCase) (EC 2.1.3.3) (Ornithine carbamoyltransferase, mitochondrial)" OTC Homo sapiens (Human) ammonium homeostasis [GO:0097272]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]; liver development [GO:0001889]; midgut development [GO:0007494]; monoatomic anion homeostasis [GO:0055081]; ornithine catabolic process [GO:0006593]; response to biotin [GO:0070781]; response to insulin [GO:0032868]; response to xenobiotic stimulus [GO:0009410]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050] mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] amino acid binding [GO:0016597]; identical protein binding [GO:0042802]; ornithine carbamoyltransferase activity [GO:0004585]; phosphate ion binding [GO:0042301]; phospholipid binding [GO:0005543] 0.92979 -1.24 LAEQYAKENGTK 11.9637 0 0 0 0 0 0 0 8.71887 0 0 0 0 0 0 0 0 0 0 0 9.51865 0 0 0 0 0 0 P00488 F13A_HUMAN Coagulation factor XIII A chain (Coagulation factor XIIIa) (EC 2.3.2.13) (Protein-glutamine gamma-glutamyltransferase A chain) (Transglutaminase A chain) F13A1 F13A Homo sapiens (Human) "blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; peptide cross-linking [GO:0018149]" blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; platelet alpha granule lumen [GO:0031093]; transferase complex [GO:1990234] metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810] 0.84845 0.17119 ETFDVTLEPLSFK 0 0 0 0 0 0 0 0 0 10.0322 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P00491 PNPH_HUMAN Purine nucleoside phosphorylase (PNP) (EC 2.4.2.1) (Inosine phosphorylase) (Inosine-guanosine phosphorylase) PNP NP Homo sapiens (Human) allantoin metabolic process [GO:0000255]; dAMP catabolic process [GO:0046059]; deoxyadenosine catabolic process [GO:0006157]; deoxyinosine catabolic process [GO:0006149]; immune response [GO:0006955]; IMP catabolic process [GO:0006204]; inosine catabolic process [GO:0006148]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of T cell proliferation [GO:0042102]; purine ribonucleoside salvage [GO:0006166]; purine-containing compound salvage [GO:0043101]; response to xenobiotic stimulus [GO:0009410]; urate biosynthetic process [GO:0034418] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774] guanosine phosphorylase activity [GO:0047975]; identical protein binding [GO:0042802]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731] 0.10575 1.1481 LTQAQIFDYGEIPNFPR 0 0 0 0 0 0 0 0 0 0 9.12412 0 0 0 0 0 0 0 0 0 0 0 0 0 9.64151 0 0 P00492 HPRT_HUMAN Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase) (EC 2.4.2.8) HPRT1 HPRT Homo sapiens (Human) adenine metabolic process [GO:0046083]; AMP salvage [GO:0044209]; central nervous system neuron development [GO:0021954]; cerebral cortex neuron differentiation [GO:0021895]; dendrite morphogenesis [GO:0048813]; dopamine metabolic process [GO:0042417]; dopaminergic neuron differentiation [GO:0071542]; GMP catabolic process [GO:0046038]; GMP salvage [GO:0032263]; grooming behavior [GO:0007625]; guanine salvage [GO:0006178]; hypoxanthine metabolic process [GO:0046100]; hypoxanthine salvage [GO:0043103]; IMP metabolic process [GO:0046040]; IMP salvage [GO:0032264]; locomotory behavior [GO:0007626]; lymphocyte proliferation [GO:0046651]; positive regulation of dopamine metabolic process [GO:0045964]; protein homotetramerization [GO:0051289]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside salvage [GO:0006166]; response to amphetamine [GO:0001975]; striatum development [GO:0021756]; T cell mediated cytotoxicity [GO:0001913] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062] guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166] 0.96323 -2.4402 ALNRNSDR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.56733 0 0 10.2836 0 0 0 0 0 0 0 0 0 0 P00505 AATM_HUMAN "Aspartate aminotransferase, mitochondrial (mAspAT) (EC 2.6.1.1) (EC 2.6.1.7) (Fatty acid-binding protein) (FABP-1) (Glutamate oxaloacetate transaminase 2) (Kynurenine aminotransferase 4) (Kynurenine aminotransferase IV) (Kynurenine--oxoglutarate transaminase 4) (Kynurenine--oxoglutarate transaminase IV) (Plasma membrane-associated fatty acid-binding protein) (FABPpm) (Transaminase A)" GOT2 KYAT4 Homo sapiens (Human) 2-oxoglutarate metabolic process [GO:0006103]; 4-hydroxyproline catabolic process [GO:0019470]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; fatty acid transport [GO:0015908]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; oxaloacetate metabolic process [GO:0006107]; response to ethanol [GO:0045471] extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886] kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]; RNA binding [GO:0003723] 0 14.957 DAGMQLQGYR 0 8.63833 0 0 0 0 0 0 0 8.49729 9.0124 10.6422 0 9.65399 0 9.4224 10.0206 9.65703 8.79442 0 8.61916 0 0 0 8.94468 0 10.5335 P00519 ABL1_HUMAN Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150) ABL1 ABL JTK7 Homo sapiens (Human) "actin cytoskeleton organization [GO:0030036]; actin filament polymerization [GO:0030041]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; associative learning [GO:0008306]; autophagy [GO:0006914]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; B-1 B cell homeostasis [GO:0001922]; Bergmann glial cell differentiation [GO:0060020]; BMP signaling pathway [GO:0030509]; cardiac muscle cell proliferation [GO:0060038]; cell-cell adhesion [GO:0098609]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular senescence [GO:0090398]; cerebellum morphogenesis [GO:0021587]; DN4 thymocyte differentiation [GO:1904157]; DNA conformation change [GO:0071103]; DNA damage response [GO:0006974]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; myoblast proliferation [GO:0051450]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; podocyte apoptotic process [GO:1903210]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel branching [GO:1905555]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of dendrite development [GO:1900006]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of extracellular matrix organization [GO:1903055]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type II interferon production [GO:0032729]; positive regulation of vasoconstriction [GO:0045907]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein localization to cytoplasmic microtubule plus-end [GO:1904518]; protein modification process [GO:0036211]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell cycle [GO:0051726]; regulation of cell motility [GO:2000145]; regulation of DNA-templated transcription [GO:0006355]; regulation of endocytosis [GO:0030100]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of T cell differentiation [GO:0045580]; response to endoplasmic reticulum stress [GO:0034976]; response to epinephrine [GO:0071871]; response to oxidative stress [GO:0006979]; response to xenobiotic stimulus [GO:0009410]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]" actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; growth cone [GO:0030426]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]; ruffle [GO:0001726] actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; delta-catenin binding [GO:0070097]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein self-association [GO:0043621]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713] 0.96947 -6.5136 AGENRSDQVTR 0 0 0 0 0 0 0 10.0626 0 0 0 0 0 0 0 0 0 0 9.26686 9.23542 0 11.163 0 0 0 0 0 P00533 EGFR_HUMAN Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1) EGFR ERBB ERBB1 HER1 Homo sapiens (Human) activation of phospholipase C activity [GO:0007202]; cell morphogenesis [GO:0000902]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; digestive tract morphogenesis [GO:0048546]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; epithelial cell proliferation [GO:0050673]; ERBB2-EGFR signaling pathway [GO:0038134]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; learning or memory [GO:0007611]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein catabolic process [GO:0042177]; neurogenesis [GO:0022008]; ossification [GO:0001503]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] "basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; intracellular vesicle [GO:0097708]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; Shc-EGFR complex [GO:0070435]" actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor receptor activity [GO:0005006]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; MAP kinase kinase kinase activity [GO:0004709]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activator activity [GO:0030296]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618] 0.96991 -5.1466 CKKCEGPCR 0 0 0 0 0 9.15081 0 0 0 0 0 0 0 9.0847 0 0 0 0 0 0 0 9.24783 9.41301 0 0 0 10.1109 P00540 MOS_HUMAN Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte maturation factor mos) (Proto-oncogene c-Mos) MOS Homo sapiens (Human) chromatin organization [GO:0006325]; establishment of meiotic spindle orientation [GO:0051296]; MAPK cascade [GO:0000165]; meiotic spindle organization [GO:0000212]; negative regulation of metaphase/anaphase transition of meiotic cell cycle [GO:1902103]; positive regulation of MAPK cascade [GO:0043410]; protein autophosphorylation [GO:0046777]; regulation of meiotic nuclear division [GO:0040020]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829] ATP binding [GO:0005524]; MAP kinase kinase kinase activity [GO:0004709]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.55983 0.5372 LLLGATLPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0373 0 0 0 0 P00558 PGK1_HUMAN Phosphoglycerate kinase 1 (EC 2.7.2.3) (Cell migration-inducing gene 10 protein) (Primer recognition protein 2) (PRP 2) PGK1 PGKA MIG10 OK/SW-cl.110 Homo sapiens (Human) canonical glycolysis [GO:0061621]; cellular response to hypoxia [GO:0071456]; epithelial cell differentiation [GO:0030855]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; negative regulation of angiogenesis [GO:0016525]; phosphorylation [GO:0016310]; plasminogen activation [GO:0031639] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; membrane raft [GO:0045121] ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]; protein-disulfide reductase (NAD(P)) activity [GO:0047134] 0 62.992 AGGFLMK 12.0982 11.7563 11.8904 0 0 0 12.6531 11.8711 12.4254 10.1943 11.6328 10.8131 12.1409 12.2202 12.5114 11.3397 13.1641 11.7457 13.3637 13.3614 12.7384 13.1965 12.7889 12.5106 13.728 13.9293 13.176 P00709 LALBA_HUMAN Alpha-lactalbumin (Lactose synthase B protein) (Lysozyme-like protein 7) LALBA LYZL7 Homo sapiens (Human) apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; defense response to bacterium [GO:0042742]; lactose biosynthetic process [GO:0005989]; signal transduction [GO:0007165] extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; protein-containing complex [GO:0032991] calcium ion binding [GO:0005509]; lactose synthase activity [GO:0004461]; lysozyme activity [GO:0003796] 0.91371 -0.80165 LEQWLCEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6177 0 0 0 0 0 0 0 0 0 0 0 0 P00734 THRB_HUMAN Prothrombin (EC 3.4.21.5) (Coagulation factor II) [Cleaved into: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain] F2 Homo sapiens (Human) "acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, common pathway [GO:0072377]; cell surface receptor signaling pathway [GO:0007166]; cytolysis by host of symbiont cells [GO:0051838]; fibrinolysis [GO:0042730]; ion channel modulating, G protein-coupled receptor signaling pathway [GO:0099105]; ligand-gated ion channel signaling pathway [GO:1990806]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of blood coagulation [GO:0030195]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil-mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of insulin secretion [GO:0032024]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to wounding [GO:0009611]; zymogen activation [GO:0031638]" blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type endopeptidase complex [GO:1905370] calcium ion binding [GO:0005509]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053] 0.89935 -0.65595 KSPQELLCGASLISDR 9.0778 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P00736 C1R_HUMAN Complement C1r subcomponent (EC 3.4.21.41) (Complement component 1 subcomponent r) [Cleaved into: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain] C1R Homo sapiens (Human) "complement activation, classical pathway [GO:0006958]; immune response [GO:0006955]; innate immune response [GO:0045087]; zymogen activation [GO:0031638]" blood microparticle [GO:0072562]; complement component C1 complex [GO:0005602]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615] calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; molecular sequestering activity [GO:0140313]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236] 0.22977 0.87018 KEFMSQGNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.95552 0 0 0 0 0 8.95809 0 10.0239 0 0 0 0 P00738 HPT_HUMAN Haptoglobin (Zonulin) [Cleaved into: Haptoglobin alpha chain; Haptoglobin beta chain] HP Homo sapiens (Human) acute inflammatory response [GO:0002526]; acute-phase response [GO:0006953]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; negative regulation of hydrogen peroxide catabolic process [GO:2000296]; negative regulation of oxidoreductase activity [GO:0051354]; positive regulation of cell death [GO:0010942]; response to hydrogen peroxide [GO:0042542] blood microparticle [GO:0072562]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724] antioxidant activity [GO:0016209]; hemoglobin binding [GO:0030492]; serine-type endopeptidase activity [GO:0004252] 0.95323 -1.4972 TEGDGVYTLNNEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.46881 9.41301 0 0 0 0 P00740 FA9_HUMAN Coagulation factor IX (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Cleaved into: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain] F9 Homo sapiens (Human) "blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]" collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; serine-type endopeptidase complex [GO:1905370] calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252] 0.76065 0.29137 TTEFWKQYVDGDQCESNPCLNGGSCK 0 0 0 0 9.12021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P00747 PLMN_HUMAN "Plasminogen (EC 3.4.21.7) [Cleaved into: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B]" PLG Homo sapiens (Human) biological process involved in interaction with symbiont [GO:0051702]; blood coagulation [GO:0007596]; extracellular matrix disassembly [GO:0022617]; fibrinolysis [GO:0042730]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of fibrinolysis [GO:0051918]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of fibrinolysis [GO:0051919]; proteolysis [GO:0006508]; tissue remodeling [GO:0048771] blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093] apolipoprotein binding [GO:0034185]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; kinase binding [GO:0019900]; protease binding [GO:0002020]; protein antigen binding [GO:1990405]; protein domain specific binding [GO:0019904]; protein-folding chaperone binding [GO:0051087]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102] 0.95899 -1.7161 NYCRNPDR 0 0 0 0 0 0 0 0 0 9.07433 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P00748 FA12_HUMAN Coagulation factor XII (EC 3.4.21.38) (Hageman factor) (HAF) [Cleaved into: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Coagulation factor XIIa light chain (Beta-factor XIIa part 2)] F12 Homo sapiens (Human) "blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; Factor XII activation [GO:0002542]; fibrinolysis [GO:0042730]; innate immune response [GO:0045087]; plasma kallikrein-kinin cascade [GO:0002353]; positive regulation of blood coagulation [GO:0030194]; positive regulation of fibrinolysis [GO:0051919]; positive regulation of plasminogen activation [GO:0010756]; protein autoprocessing [GO:0016540]; protein processing [GO:0016485]; proteolysis [GO:0006508]; response to misfolded protein [GO:0051788]; zymogen activation [GO:0031638]" collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; serine-type endopeptidase complex [GO:1905370] calcium ion binding [GO:0005509]; misfolded protein binding [GO:0051787]; serine-type endopeptidase activity [GO:0004252] 0.95469 -1.522 CQCKGPDAHCQR 0 14.005 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P00749 UROK_HUMAN Urokinase-type plasminogen activator (U-plasminogen activator) (uPA) (EC 3.4.21.73) [Cleaved into: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B] PLAU Homo sapiens (Human) blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of plasminogen activation [GO:0010757]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion [GO:0030155]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of fibrinolysis [GO:0051917]; regulation of plasminogen activation [GO:0010755]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]; urokinase plasminogen activator signaling pathway [GO:0038195] cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; protein complex involved in cell-matrix adhesion [GO:0098637]; serine protease inhibitor complex [GO:0097180]; serine-type endopeptidase complex [GO:1905370]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821] serine-type endopeptidase activity [GO:0004252] 0.95254 -1.4743 FGGQHCEIDKSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1976 0 0 0 0 0 0 0 0 0 0 0 P00750 TPA_HUMAN Tissue-type plasminogen activator (t-PA) (t-plasminogen activator) (tPA) (EC 3.4.21.68) (Alteplase) (Reteplase) [Cleaved into: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B] PLAT Homo sapiens (Human) "blood coagulation [GO:0007596]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to luteinizing hormone stimulus [GO:0071373]; fibrinolysis [GO:0042730]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of plasminogen activation [GO:0010757]; negative regulation of proteolysis [GO:0045861]; plasminogen activation [GO:0031639]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of ovulation [GO:0060279]; prevention of polyspermy [GO:0060468]; protein modification process [GO:0036211]; proteolysis [GO:0006508]; regulation of synaptic plasticity [GO:0048167]; response to cAMP [GO:0051591]; response to fatty acid [GO:0070542]; response to hypoxia [GO:0001666]; smooth muscle cell migration [GO:0014909]; synaptic transmission, glutamatergic [GO:0035249]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]" apical part of cell [GO:0045177]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; neuronal dense core vesicle [GO:0098992]; perisynaptic space [GO:0099544]; postsynapse [GO:0098794]; Schaffer collateral - CA1 synapse [GO:0098685]; serine protease inhibitor complex [GO:0097180] phosphoprotein binding [GO:0051219]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102] 0.60235 0.44067 GTHSLTESGASCLPWNSMILIGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.18753 0 0 0 9.64829 10.4936 0 P00751 CFAB_HUMAN Complement factor B (EC 3.4.21.47) (C3/C5 convertase) (Glycine-rich beta glycoprotein) (GBG) (PBF2) (Properdin factor B) [Cleaved into: Complement factor B Ba fragment; Complement factor B Bb fragment] CFB BF BFD Homo sapiens (Human) "complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; positive regulation of immune response [GO:0050778]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508]" blood microparticle [GO:0072562]; classical-complement-pathway C3/C5 convertase complex [GO:0005601]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] complement binding [GO:0001848]; serine-type endopeptidase activity [GO:0004252] 0.96948 -4.615 DISEVVTPR 0 0 0 0 0 0 0 0 0 8.5678 0 0 0 0 0 0 0 0 0 0 0 9.62401 0 0 0 0 0 P00915 CAH1_HUMAN Carbonic anhydrase 1 (EC 4.2.1.1) (Carbonate dehydratase I) (Carbonic anhydrase B) (CAB) (Carbonic anhydrase I) (CA-I) (Cyanamide hydratase CA1) (EC 4.2.1.69) CA1 Homo sapiens (Human) cytosol [GO:0005829]; extracellular exosome [GO:0070062] arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; cyanamide hydratase activity [GO:0018820]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270] 0.96763 -2.856 VGEANPK 0 0 8.93192 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1815 0 0 P00918 CAH2_HUMAN Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase C) (CAC) (Carbonic anhydrase II) (CA-II) (Cyanamide hydratase CA2) (EC 4.2.1.69) CA2 Homo sapiens (Human) "angiotensin-activated signaling pathway [GO:0038166]; carbon dioxide transport [GO:0015670]; morphogenesis of an epithelium [GO:0002009]; neuron cellular homeostasis [GO:0070050]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; regulation of monoatomic anion transport [GO:0044070]; secretion [GO:0046903]" apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886] arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; cyanamide hydratase activity [GO:0018820]; zinc ion binding [GO:0008270] 0.73744 0.32554 GGPLDGTYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1219 P00973 OAS1_HUMAN 2'-5'-oligoadenylate synthase 1 ((2-5')oligo(A) synthase 1) (2-5A synthase 1) (EC 2.7.7.84) (E18/E16) (p46/p42 OAS) OAS1 OIAS Homo sapiens (Human) antiviral innate immune response [GO:0140374]; cellular response to interferon-alpha [GO:0035457]; cellular response to interferon-beta [GO:0035458]; cellular response to virus [GO:0098586]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; interleukin-27-mediated signaling pathway [GO:0070106]; negative regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000342]; negative regulation of IP-10 production [GO:0071659]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cellular respiration [GO:1901857]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of tumor necrosis factor production [GO:0032760]; protein complex oligomerization [GO:0051259]; regulation of ribonuclease activity [GO:0060700]; response to virus [GO:0009615]; surfactant homeostasis [GO:0043129]; toll-like receptor 3 signaling pathway [GO:0034138]; toll-like receptor 4 signaling pathway [GO:0034142]; type I interferon-mediated signaling pathway [GO:0060337] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribosome [GO:0005840] 2'-5'-oligoadenylate synthetase activity [GO:0001730]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872] 0.96006 -1.7984 AFSVKFEVQAPR 0 0 0 0 0 0 0 0 9.86494 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.7301 9.55855 0 P01008 ANT3_HUMAN Antithrombin-III (ATIII) (Serpin C1) SERPINC1 AT3 PRO0309 Homo sapiens (Human) blood coagulation [GO:0007596]; negative regulation of peptidase activity [GO:0010466]; regulation of blood coagulation [GO:0030193] blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; serine-type endopeptidase inhibitor activity [GO:0004867] 0.0057471 2.3201 LPGIVAEGR 0 0 0 0 0 0 0 0 9.27589 9.53531 0 9.89448 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P01009 A1AT_HUMAN Alpha-1-antitrypsin (Alpha-1 protease inhibitor) (Alpha-1-antiproteinase) (Serpin A1) [Cleaved into: Short peptide from AAT (SPAAT)] SERPINA1 AAT PI PRO0684 PRO2209 Homo sapiens (Human) acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; negative regulation of endopeptidase activity [GO:0010951] collagen-containing extracellular matrix [GO:0062023]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; platelet alpha granule lumen [GO:0031093] identical protein binding [GO:0042802]; protease binding [GO:0002020]; serine-type endopeptidase inhibitor activity [GO:0004867] 0.86409 0.077694 SPLFMGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3574 0 0 0 0 0 0 0 0 0 0 0 0 P01023 A2MG_HUMAN Alpha-2-macroglobulin (Alpha-2-M) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5) A2M CPAMD5 FWP007 Homo sapiens (Human) "acute inflammatory response to antigenic stimulus [GO:0002438]; acute-phase response [GO:0006953]; embryonic liver development [GO:1990402]; luteinization [GO:0001553]; negative regulation of complement activation, lectin pathway [GO:0001869]; negative regulation of endopeptidase activity [GO:0010951]; response to carbon dioxide [GO:0010037]; response to glucocorticoid [GO:0051384]; response to nutrient [GO:0007584]; response to prostaglandin E [GO:0034695]; stem cell differentiation [GO:0048863]" blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; platelet alpha granule lumen [GO:0031093] brain-derived neurotrophic factor binding [GO:0048403]; calcium-dependent protein binding [GO:0048306]; endopeptidase inhibitor activity [GO:0004866]; enzyme binding [GO:0019899]; growth factor binding [GO:0019838]; identical protein binding [GO:0042802]; interleukin-1 binding [GO:0019966]; interleukin-8 binding [GO:0019959]; nerve growth factor binding [GO:0048406]; protease binding [GO:0002020]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor binding [GO:0005102]; tumor necrosis factor binding [GO:0043120] 0 5.9487 ATVLNYLPK 0 0 0 0 0 0 0 0 0 11.8069 11.5257 11.6361 9.67152 10.668 10.0651 9.41994 8.52787 10.5749 0 0 0 0 0 0 0 0 0 P01024 CO3_HUMAN Complement C3 (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1) [Cleaved into: Complement C3 beta chain; C3-beta-c (C3bc); Complement C3 alpha chain; C3a anaphylatoxin; Acylation stimulating protein (ASP) (C3adesArg); Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment; Complement C3c alpha' chain fragment 2] C3 CPAMD1 Homo sapiens (Human) "amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; opsonization [GO:0008228]; oviduct epithelium development [GO:0035846]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of apoptotic process in another organism [GO:0044533]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of immune response [GO:0050778]; positive regulation of lipid storage [GO:0010884]; positive regulation of opsonization [GO:1903028]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; proteolysis [GO:0006508]; regulation of complement activation [GO:0030449]; regulation of complement activation, alternative pathway [GO:0030451]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]" azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; serine-type endopeptidase complex [GO:1905370] C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102] 0.96904 -5.7442 AKDQLTCNKFDLK 0 0 0 0 0 0 9.40818 0 0 0 9.94997 12.4047 0 0 9.19911 0 0 16.272 0 0 0 0 0 0 0 0 0 P01031 CO5_HUMAN Complement C5 (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4) [Cleaved into: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain] C5 CPAMD4 Homo sapiens (Human) "cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; G protein-coupled receptor signaling pathway [GO:0007186]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; killing of cells of another organism [GO:0031640]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine production [GO:0032722]; positive regulation of immune response [GO:0050778]; positive regulation of vascular endothelial growth factor production [GO:0010575]" extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579] chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102] 0.89716 -0.67674 GIYGTISR 0 0 0 0 0 0 0 0 0 0 10.9878 0 0 0 0 0 0 14.6611 0 8.81295 0 0 0 0 10.4485 0 0 P01033 TIMP1_HUMAN Metalloproteinase inhibitor 1 (Erythroid-potentiating activity) (EPA) (Fibroblast collagenase inhibitor) (Collagenase inhibitor) (Tissue inhibitor of metalloproteinases 1) (TIMP-1) TIMP1 CLGI TIMP Homo sapiens (Human) aging [GO:0007568]; cartilage development [GO:0051216]; cell activation [GO:0001775]; cellular response to UV-A [GO:0071492]; connective tissue replacement involved in inflammatory response wound healing [GO:0002248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of metallopeptidase activity [GO:1905049]; negative regulation of trophoblast cell migration [GO:1901164]; positive regulation of cell population proliferation [GO:0008284]; regulation of integrin-mediated signaling pathway [GO:2001044]; response to cytokine [GO:0034097]; response to hormone [GO:0009725]; response to peptide hormone [GO:0043434] basement membrane [GO:0005604]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; platelet alpha granule lumen [GO:0031093] cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; metalloendopeptidase inhibitor activity [GO:0008191]; peptidase inhibitor activity [GO:0030414]; protease binding [GO:0002020]; zinc ion binding [GO:0008270] 0.84821 0.15737 HLACLPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6177 0 0 0 0 0 0 0 0 0 P01042 KNG1_HUMAN Kininogen-1 (Alpha-2-thiol proteinase inhibitor) (Fitzgerald factor) (High molecular weight kininogen) (HMWK) (Williams-Fitzgerald-Flaujeac factor) [Cleaved into: Kininogen-1 heavy chain; T-kinin (Ile-Ser-Bradykinin); Bradykinin (Kallidin I); Lysyl-bradykinin (Kallidin II); Kininogen-1 light chain; Low molecular weight growth-promoting factor] KNG1 BDK KNG Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; inflammatory response [GO:0006954]; killing of cells of another organism [GO:0031640]; negative regulation of blood coagulation [GO:0030195]; negative regulation of cell adhesion [GO:0007162]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of proteolysis [GO:0045861]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; vasodilation [GO:0042311] blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093] cysteine-type endopeptidase inhibitor activity [GO:0004869]; heparin binding [GO:0008201]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]; zinc ion binding [GO:0008270] 0.96941 -3.2145 KYFIDFVAR 0 0 0 0 0 0 0 0 9.57667 0 0 0 0 8.70047 0 9.54129 9.68152 10.1209 0 0 0 0 0 0 0 0 0 P01116 RASK_HUMAN "GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]" KRAS KRAS2 RASK2 Homo sapiens (Human) "actin cytoskeleton organization [GO:0030036]; endocrine signaling [GO:0038002]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; forebrain astrocyte development [GO:0021897]; glial cell proliferation [GO:0014009]; homeostasis of number of cells within a tissue [GO:0048873]; MAPK cascade [GO:0000165]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of neuron apoptotic process [GO:0043524]; neuron apoptotic process [GO:0051402]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rac protein signal transduction [GO:0035022]; Rac protein signal transduction [GO:0016601]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of synaptic transmission, GABAergic [GO:0032228]; skeletal muscle cell differentiation [GO:0035914]; striated muscle cell differentiation [GO:0051146]; type I pneumocyte differentiation [GO:0060509]; visual learning [GO:0008542]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; plasma membrane [GO:0005886] G protein activity [GO:0003925]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; protein serine/threonine kinase activator activity [GO:0043539]; protein-containing complex binding [GO:0044877]; protein-membrane adaptor activity [GO:0043495] 0.95459 -1.5042 TVDTKQAQDLAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0856 0 0 0 0 0 0 0 0 0 0 0 P01133 EGF_HUMAN Pro-epidermal growth factor (EGF) [Cleaved into: Epidermal growth factor (Urogastrone)] EGF Homo sapiens (Human) angiogenesis [GO:0001525]; branching morphogenesis of an epithelial tube [GO:0048754]; cerebellar granule cell precursor proliferation [GO:0021930]; epidermal growth factor receptor signaling pathway [GO:0007173]; epidermal growth factor receptor signaling pathway via MAPK cascade [GO:0038029]; epithelial cell proliferation [GO:0050673]; ERBB2-EGFR signaling pathway [GO:0038134]; ERK1 and ERK2 cascade [GO:0070371]; mammary gland alveolus development [GO:0060749]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of secretion [GO:0051048]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cerebellar granule cell precursor proliferation [GO:0021940]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA replication [GO:0045740]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of epithelial tube formation [GO:1905278]; positive regulation of gene expression [GO:0010628]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of receptor internalization [GO:0002092]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; regulation of calcium ion import [GO:0090279]; regulation of protein localization to cell surface [GO:2000008]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425] clathrin-coated endocytic vesicle membrane [GO:0030669]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093] calcium ion binding [GO:0005509]; epidermal growth factor receptor binding [GO:0005154]; growth factor activity [GO:0008083]; guanyl-nucleotide exchange factor activity [GO:0005085]; receptor ligand activity [GO:0048018]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297] 0.88329 -0.32129 GFAGDGK 0 0 0 0 0 0 0 0 0 0 0 9.86618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P01148 GON1_HUMAN Progonadoliberin-1 (Progonadoliberin I) [Cleaved into: Gonadoliberin-1 (Gonadoliberin I) (Gonadorelin) (Gonadotropin-releasing hormone I) (GnRH-I) (Luliberin I) (Luteinizing hormone-releasing hormone I) (LH-RH I); GnRH-associated peptide 1 (GnRH-associated peptide I)] GNRH1 GNRH GRH LHRH Homo sapiens (Human) cell-cell signaling [GO:0007267]; negative regulation of neuron migration [GO:2001223]; regulation of gene expression [GO:0010468]; regulation of ovarian follicle development [GO:2000354]; response to ethanol [GO:0045471]; response to steroid hormone [GO:0048545]; signal transduction [GO:0007165] extracellular region [GO:0005576]; extracellular space [GO:0005615] gonadotropin hormone-releasing hormone activity [GO:0005183]; gonadotropin-releasing hormone receptor binding [GO:0031530]; hormone activity [GO:0005179] 0.21331 0.90467 GALESLIEEETGQK 0 0 0 0 0 0 0 0 0 0 0 9.24503 0 0 0 0 0 0 0 0 0 0 0 0 0 12.7516 0 P01225 FSHB_HUMAN Follitropin subunit beta (Follicle-stimulating hormone beta subunit) (FSH-B) (FSH-beta) (Follitropin beta chain) FSHB Homo sapiens (Human) female gamete generation [GO:0007292]; female pregnancy [GO:0007565]; follicle-stimulating hormone signaling pathway [GO:0042699]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of steroid biosynthetic process [GO:0010893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; progesterone biosynthetic process [GO:0006701]; regulation of osteoclast differentiation [GO:0045670]; regulation of signaling receptor activity [GO:0010469]; Sertoli cell proliferation [GO:0060011]; spermatogenesis [GO:0007283]; transforming growth factor beta receptor signaling pathway [GO:0007179] cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; follicle-stimulating hormone complex [GO:0016914] follicle-stimulating hormone activity [GO:0016913] 0.85754 0.10092 MKTLQFFFLFCCWK 8.98524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P01236 PRL_HUMAN Prolactin (PRL) PRL Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; female pregnancy [GO:0007565]; lactation [GO:0007595]; mammary gland development [GO:0030879]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lactation [GO:1903489]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; response to nutrient levels [GO:0031667] endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615] hormone activity [GO:0005179]; prolactin receptor binding [GO:0005148] 0.90825 -0.74053 IDNYLKLLK 0 0 0 0 10.7928 0 0 0 0 10.651 0 0 0 0 10.6162 0 0 0 0 0 0 0 0 0 0 0 0 P01242 SOM2_HUMAN Growth hormone variant (GH-V) (Growth hormone 2) (Placenta-specific growth hormone) GH2 Homo sapiens (Human) animal organ development [GO:0048513]; growth hormone receptor signaling pathway [GO:0060396]; positive regulation of growth [GO:0045927]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; response to nutrient levels [GO:0031667] endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615] growth factor activity [GO:0008083]; growth hormone receptor binding [GO:0005131]; hormone activity [GO:0005179] 0.84101 0.147 DLEEGIQTLMWR 0 0 9.68256 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5142 0 P01266 THYG_HUMAN Thyroglobulin (Tg) TG Homo sapiens (Human) hormone biosynthetic process [GO:0042446]; iodide transport [GO:0015705]; regulation of myelination [GO:0031641]; signal transduction [GO:0007165]; thyroid gland development [GO:0030878]; thyroid hormone generation [GO:0006590] extracellular region [GO:0005576]; extracellular space [GO:0005615] hormone activity [GO:0005179]; identical protein binding [GO:0042802] 0.96978 -5.4189 AFCVDGEGRR 16.0643 0 0 12.0612 12.0545 12.1128 16.0694 0 0 0 15.9171 0 10.7449 8.67955 11.7446 13.7281 13.7578 13.7511 0 0 0 0 0 0 0 0 0 P01344 IGF2_HUMAN Insulin-like growth factor II (IGF-II) (Somatomedin-A) (T3M-11-derived growth factor) [Cleaved into: Insulin-like growth factor II; Insulin-like growth factor II Ala-25 Del; Preptin] IGF2 PP1446 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; embryonic placenta development [GO:0001892]; embryonic placenta morphogenesis [GO:0060669]; exocrine pancreas development [GO:0031017]; glucose metabolic process [GO:0006006]; in utero embryonic development [GO:0001701]; insulin receptor signaling pathway [GO:0008286]; insulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of muscle cell differentiation [GO:0051148]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of glycogen (starch) synthase activity [GO:2000467]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of organ growth [GO:0046622]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of skeletal muscle tissue growth [GO:0048633]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression by genomic imprinting [GO:0006349]; regulation of muscle cell differentiation [GO:0051147]; spongiotrophoblast cell proliferation [GO:0060720]; striated muscle cell differentiation [GO:0051146] extracellular region [GO:0005576]; extracellular space [GO:0005615]; platelet alpha granule lumen [GO:0031093] growth factor activity [GO:0008083]; hormone activity [GO:0005179]; insulin receptor binding [GO:0005158]; insulin-like growth factor receptor binding [GO:0005159]; integrin binding [GO:0005178]; protein serine/threonine kinase activator activity [GO:0043539]; receptor ligand activity [GO:0048018]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297] 0.88395 -0.28055 YPVGKFFQYDTWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.56182 0 0 0 0 0 0 0 0 P01374 TNFB_HUMAN Lymphotoxin-alpha (LT-alpha) (TNF-beta) (Tumor necrosis factor ligand superfamily member 1) LTA TNFB TNFSF1 Homo sapiens (Human) apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; lymph node development [GO:0048535]; negative regulation of fibroblast proliferation [GO:0048147]; positive regulation of apoptotic process [GO:0043065]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of type II interferon production [GO:0032729]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; response to nutrient [GO:0007584]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165] extracellular space [GO:0005615]; plasma membrane [GO:0005886] cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164] 0.96896 -3.3761 QNSLLWR 0 0 0 0 0 0 0 0 8.85652 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P01583 IL1A_HUMAN Interleukin-1 alpha (IL-1 alpha) (Hematopoietin-1) IL1A IL1F1 Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to heat [GO:0034605]; cellular response to lipopolysaccharide [GO:0071222]; connective tissue replacement involved in inflammatory response wound healing [GO:0002248]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; heart development [GO:0007507]; immune response [GO:0006955]; inflammatory response [GO:0006954]; intracellular sodium ion homeostasis [GO:0006883]; keratinization [GO:0031424]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of establishment of Sertoli cell barrier [GO:1904445]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cytokine production [GO:0001819]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of immature T cell proliferation in thymus [GO:0033092]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of neutrophil migration [GO:1902624]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein secretion [GO:0050714]; positive regulation of steroid biosynthetic process [GO:0010893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of sensory perception of pain [GO:0051930]; response to copper ion [GO:0046688]; response to gamma radiation [GO:0010332]; response to hypoxia [GO:0001666]; response to L-ascorbic acid [GO:0033591]; response to organonitrogen compound [GO:0010243]; response to ozone [GO:0010193]; spermatogenesis [GO:0007283] cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886] copper ion binding [GO:0005507]; cytokine activity [GO:0005125]; interleukin-1 receptor binding [GO:0005149] 0.88379 -0.29771 FDMGAYKSSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.448 0 0 0 0 0 P01584 IL1B_HUMAN Interleukin-1 beta (IL-1 beta) (Catabolin) IL1B IL1F2 Homo sapiens (Human) apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to interleukin-17 [GO:0097398]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cellular response to xenobiotic stimulus [GO:0071466]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-positive bacterium [GO:0050830]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; JNK cascade [GO:0007254]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of immature T cell proliferation in thymus [GO:0033092]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type II interferon production [GO:0032729]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]; vascular endothelial growth factor production [GO:0010573] cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141] cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904] 0.90442 -0.70706 FVFNKIEINNK 0 0 0 0 0 0 12.9817 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P01591 IGJ_HUMAN Immunoglobulin J chain (Joining chain of multimeric IgA and IgM) JCHAIN IGCJ IGJ Homo sapiens (Human) adaptive immune response [GO:0002250]; antibacterial humoral response [GO:0019731]; glomerular filtration [GO:0003094]; humoral immune response [GO:0006959]; immune response [GO:0006955]; innate immune response [GO:0045087]; positive regulation of respiratory burst [GO:0060267]; protein-containing complex assembly [GO:0065003]; retina homeostasis [GO:0001895] blood microparticle [GO:0072562]; dimeric IgA immunoglobulin complex [GO:0071750]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; monomeric IgA immunoglobulin complex [GO:0071748]; pentameric IgM immunoglobulin complex [GO:0071756]; secretory dimeric IgA immunoglobulin complex [GO:0071752]; secretory IgA immunoglobulin complex [GO:0071751] antigen binding [GO:0003823]; IgA binding [GO:0019862]; immunoglobulin receptor binding [GO:0034987]; protein homodimerization activity [GO:0042803]; protein-macromolecule adaptor activity [GO:0030674] 0 4.0069 CYTAVVPLVYGGETK 0 0 0 0 0 0 0 9.70541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P01601 KVD16_HUMAN Immunoglobulin kappa variable 1D-16 (Ig kappa chain V-I region HK146) (Ig kappa chain V-I region HK189) IGKV1D-16 Homo sapiens (Human) adaptive immune response [GO:0002250]; immune response [GO:0006955] extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886] antigen binding [GO:0003823] 0.87095 0.059873 SLIYAASSLQSGVPSR 0 0 0 0 0 0 0 0 0 0 0 9.8238 0 0 0 0 0 0 0 0 0 10.9347 0 0 0 0 0 P01700 LV147_HUMAN Immunoglobulin lambda variable 1-47 (Ig lambda chain V-I region HA) (Ig lambda chain V-I region WAH) IGLV1-47 Homo sapiens (Human) adaptive immune response [GO:0002250]; immune response [GO:0006955] blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886] antigen binding [GO:0003823] 0.84197 0.14975 LLIYSNNQRPSGVPDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4303 0 0 P01730 CD4_HUMAN T-cell surface glycoprotein CD4 (T-cell surface antigen T4/Leu-3) (CD antigen CD4) CD4 Homo sapiens (Human) adaptive immune response [GO:0002250]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; defense response to Gram-negative bacterium [GO:0050829]; enzyme-linked receptor protein signaling pathway [GO:0007167]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell activation [GO:0050870]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of T cell activation [GO:0050863]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101] coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; lipid binding [GO:0008289]; MHC class II protein binding [GO:0042289]; MHC class II protein complex binding [GO:0023026]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270] 0.91321 -0.76225 SIQFHWKNSNQIK 0 0 0 0 0 0 0 0 0 0 0 10.8829 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P01833 PIGR_HUMAN Polymeric immunoglobulin receptor (PIgR) (Poly-Ig receptor) (Hepatocellular carcinoma-associated protein TB6) [Cleaved into: Secretory component] PIGR Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; epidermal growth factor receptor signaling pathway [GO:0007173]; Fc receptor signaling pathway [GO:0038093]; immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor [GO:0002415]; receptor clustering [GO:0043113]; retina homeostasis [GO:0001895] azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; secretory IgA immunoglobulin complex [GO:0071751] polymeric immunoglobulin receptor activity [GO:0001792]; transmembrane signaling receptor activity [GO:0004888] 0.93318 -1.2846 EEFVATTESTTETKEPK 0 0 0 0 0 0 9.50766 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P01871 IGHM_HUMAN Immunoglobulin heavy constant mu (Ig mu chain C region) (Ig mu chain C region BOT) (Ig mu chain C region GAL) (Ig mu chain C region OU) IGHM Homo sapiens (Human) adaptive immune response [GO:0002250]; antibacterial humoral response [GO:0019731]; B cell receptor signaling pathway [GO:0050853]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response [GO:0045087] blood microparticle [GO:0072562]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; hexameric IgM immunoglobulin complex [GO:0071757]; IgM immunoglobulin complex [GO:0071753]; pentameric IgM immunoglobulin complex [GO:0071756]; plasma membrane [GO:0005886] antigen binding [GO:0003823] 0.63003 0.39959 QNGEAVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.57901 0 0 0 0 0 0 0 0 0 0 7.9377 P01920 DQB1_HUMAN "HLA class II histocompatibility antigen, DQ beta 1 chain (MHC class II antigen DQB1)" HLA-DQB1 HLA-DQB Homo sapiens (Human) adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; humoral immune response [GO:0006959]; immune response [GO:0006955]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; positive regulation of T cell activation [GO:0050870]; T cell receptor signaling pathway [GO:0050852] clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; lumenal side of endoplasmic reticulum membrane [GO:0098553]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658] MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605] 0.95053 -1.4064 AELDTVCRHNYQLELR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7507 0 0 0 0 0 10.6284 0 0 0 11.1292 0 P02008 HBAZ_HUMAN Hemoglobin subunit zeta (HBAZ) (Hemoglobin zeta chain) (Zeta-globin) HBZ HBZ2 Homo sapiens (Human) carbon dioxide transport [GO:0015670]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942] extracellular exosome [GO:0070062]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833] heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344] 0.78811 0.24993 SIDDIGGALSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.73515 0 0 0 0 P02144 MYG_HUMAN Myoglobin MB Homo sapiens (Human) brown fat cell differentiation [GO:0050873]; enucleate erythrocyte differentiation [GO:0043353]; heart development [GO:0007507]; oxygen transport [GO:0015671]; response to hypoxia [GO:0001666] cytosol [GO:0005829]; extracellular exosome [GO:0070062] heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344] 0.8823 -0.27241 DMASNYKELGFQG 0 0 9.87315 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P02452 CO1A1_HUMAN Collagen alpha-1(I) chain (Alpha-1 type I collagen) COL1A1 Homo sapiens (Human) blood vessel development [GO:0001568]; bone trabecula formation [GO:0060346]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; cellular response to amino acid stimulus [GO:0071230]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to fluoride [GO:1902618]; cellular response to mechanical stimulus [GO:0071260]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vitamin E [GO:0071306]; collagen biosynthetic process [GO:0032964]; collagen fibril organization [GO:0030199]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; embryonic skeletal system development [GO:0048706]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; face morphogenesis [GO:0060325]; intramembranous ossification [GO:0001957]; negative regulation of cell-substrate adhesion [GO:0010812]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; protein localization to nucleus [GO:0034504]; protein transport [GO:0015031]; response to cAMP [GO:0051591]; response to corticosteroid [GO:0031960]; response to estradiol [GO:0032355]; response to hydrogen peroxide [GO:0042542]; response to hyperoxia [GO:0055093]; response to insulin [GO:0032868]; response to mechanical stimulus [GO:0009612]; response to xenobiotic stimulus [GO:0009410]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]; skin development [GO:0043588]; skin morphogenesis [GO:0043589]; tooth eruption [GO:0044691]; tooth mineralization [GO:0034505]; visual perception [GO:0007601]; wound healing [GO:0042060] collagen type I trimer [GO:0005584]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; secretory granule [GO:0030141] extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; platelet-derived growth factor binding [GO:0048407]; protease binding [GO:0002020] 0.96738 -2.8104 DGSPGAK 0 0 0 0 0 0 0 8.0698 10.2104 0 0 0 0 10.5158 0 0 0 0 0 0 0 9.60986 0 10.3098 10.8546 0 0 P02458 CO2A1_HUMAN Collagen alpha-1(II) chain (Alpha-1 type II collagen) [Cleaved into: Collagen alpha-1(II) chain; Chondrocalcin] COL2A1 Homo sapiens (Human) anterior head development [GO:0097065]; cartilage condensation [GO:0001502]; cartilage development [GO:0051216]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; cellular response to BMP stimulus [GO:0071773]; central nervous system development [GO:0007417]; chondrocyte differentiation [GO:0002062]; collagen fibril organization [GO:0030199]; embryonic skeletal joint morphogenesis [GO:0060272]; endochondral ossification [GO:0001958]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; heart morphogenesis [GO:0003007]; inner ear morphogenesis [GO:0042472]; limb bud formation [GO:0060174]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; notochord development [GO:0030903]; otic vesicle development [GO:0071599]; proteoglycan metabolic process [GO:0006029]; regulation of gene expression [GO:0010468]; roof of mouth development [GO:0060021]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]; tissue homeostasis [GO:0001894]; visual perception [GO:0007601] basement membrane [GO:0005604]; collagen type II trimer [GO:0005585]; collagen type XI trimer [GO:0005592]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020]; metal ion binding [GO:0046872]; MHC class II protein binding [GO:0042289]; platelet-derived growth factor binding [GO:0048407]; protein homodimerization activity [GO:0042803]; proteoglycan binding [GO:0043394] 0.97011 -4.1581 AEGNSRFTYTALK 0 0 0 0 0 0 0 0 0 0 14.4939 0 0 0 0 9.85922 0 0 10.4368 0 0 0 10.0921 0 0 0 0 P02461 CO3A1_HUMAN Collagen alpha-1(III) chain COL3A1 Homo sapiens (Human) aorta smooth muscle tissue morphogenesis [GO:0060414]; basement membrane organization [GO:0071711]; cell-matrix adhesion [GO:0007160]; cellular response to amino acid stimulus [GO:0071230]; cerebral cortex development [GO:0021987]; chondrocyte differentiation [GO:0002062]; collagen fibril organization [GO:0030199]; digestive tract development [GO:0048565]; elastic fiber assembly [GO:0048251]; endochondral bone morphogenesis [GO:0060350]; extracellular matrix organization [GO:0030198]; fibroblast proliferation [GO:0048144]; heart development [GO:0007507]; in utero embryonic development [GO:0001701]; integrin-mediated signaling pathway [GO:0007229]; layer formation in cerebral cortex [GO:0021819]; limb joint morphogenesis [GO:0036022]; lung development [GO:0030324]; multicellular organism growth [GO:0035264]; negative regulation of immune response [GO:0050777]; negative regulation of neuron migration [GO:2001223]; neuron migration [GO:0001764]; peptide cross-linking [GO:0018149]; platelet activation [GO:0030168]; positive regulation of Rho protein signal transduction [GO:0035025]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to radiation [GO:0009314]; skin development [GO:0043588]; supramolecular fiber organization [GO:0097435]; tissue homeostasis [GO:0001894]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transforming growth factor beta1 production [GO:0032905]; wound healing [GO:0042060] collagen type III trimer [GO:0005586]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; platelet-derived growth factor binding [GO:0048407]; protease binding [GO:0002020]; SMAD binding [GO:0046332] 0.3552 0.75768 GETGERGAAGIKGHR 0 0 0 0 0 0 0 9.59264 0 0 0 0 0 0 0 0 0 0 0 0 9.57915 0 0 0 0 0 9.15689 P02489 CRYAA_HUMAN Alpha-crystallin A chain (Heat shock protein beta-4) (HspB4) [Cleaved into: Alpha-crystallin A(1-172); Alpha-crystallin A(1-168); Alpha-crystallin A(1-162)] CRYAA CRYA1 HSPB4 Homo sapiens (Human) lens development in camera-type eye [GO:0002088]; negative regulation of apoptotic process [GO:0043066]; negative regulation of intracellular transport [GO:0032387]; protein stabilization [GO:0050821]; response to stimulus [GO:0050896]; visual perception [GO:0007601] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; structural constituent of eye lens [GO:0005212]; structural molecule activity [GO:0005198]; unfolded protein binding [GO:0051082] 0.56404 0.49003 TLGPFYPSR 0 0 0 0 0 0 0 0 0 9.76881 0 9.43875 0 0 0 10.3234 0 0 0 0 0 0 0 0 0 0 0 P02511 CRYAB_HUMAN Alpha-crystallin B chain (Alpha(B)-crystallin) (Heat shock protein beta-5) (HspB5) (Renal carcinoma antigen NY-REN-27) (Rosenthal fiber component) CRYAB CRYA2 HSPB5 Homo sapiens (Human) apoptotic process involved in morphogenesis [GO:0060561]; cellular response to gamma radiation [GO:0071480]; lens development in camera-type eye [GO:0002088]; microtubule polymerization or depolymerization [GO:0031109]; multicellular organism aging [GO:0010259]; muscle contraction [GO:0006936]; muscle organ development [GO:0007517]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of intracellular transport [GO:0032387]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; regulation of programmed cell death [GO:0043067]; response to estradiol [GO:0032355]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; stress-activated MAPK cascade [GO:0051403]; tubulin complex assembly [GO:0007021] actin filament bundle [GO:0032432]; axon [GO:0030424]; cardiac myofibril [GO:0097512]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; M band [GO:0031430]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; synaptic membrane [GO:0097060]; Z disc [GO:0030018] amyloid-beta binding [GO:0001540]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; structural constituent of eye lens [GO:0005212]; structural molecule activity [GO:0005198]; unfolded protein binding [GO:0051082] 0.91294 -0.75518 HEERQDEHGFISR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1728 0 0 0 0 0 0 P02533 K1C14_HUMAN "Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14)" KRT14 Homo sapiens (Human) epidermis development [GO:0008544]; epithelial cell differentiation [GO:0030855]; hair cycle [GO:0042633]; intermediate filament bundle assembly [GO:0045110]; intermediate filament organization [GO:0045109]; keratinocyte differentiation [GO:0030216]; stem cell differentiation [GO:0048863] basal part of cell [GO:0045178]; cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; keratin filament [GO:0045095]; nucleus [GO:0005634] keratin filament binding [GO:1990254]; structural constituent of cytoskeleton [GO:0005200] 0 30.547 ALEEANADLEVK 10.3596 9.48081 0 0 0 0 10.9074 10.5527 8.97865 10.3377 10.0503 11.2567 8.82353 0 8.97163 11.4008 9.60618 11.4488 9.39947 0 9.5686 9.72339 0 0 9.03513 9.1874 0 P02545 LMNA_HUMAN Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)] LMNA LMN1 Homo sapiens (Human) cellular response to hypoxia [GO:0071456]; cellular senescence [GO:0090398]; DNA double-strand break attachment to nuclear envelope [GO:1990683]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; heterochromatin formation [GO:0031507]; muscle organ development [GO:0007517]; negative regulation of cardiac muscle hypertrophy in response to stress [GO:1903243]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of mesenchymal cell proliferation [GO:0072201]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; nuclear envelope organization [GO:0006998]; nuclear migration [GO:0007097]; nuclear pore localization [GO:0051664]; positive regulation of gene expression [GO:0010628]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein localization to nuclear envelope [GO:0090435]; protein localization to nucleus [GO:0034504]; regulation of cell migration [GO:0030334]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; ventricular cardiac muscle cell development [GO:0055015] cytosol [GO:0005829]; intermediate filament [GO:0005882]; lamin filament [GO:0005638]; nuclear envelope [GO:0005635]; nuclear lamina [GO:0005652]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; site of double-strand break [GO:0035861] identical protein binding [GO:0042802]; structural constituent of cytoskeleton [GO:0005200]; structural molecule activity [GO:0005198] 0 43.967 AAYEAELGDAR 10.5372 10.8498 10.4893 0 0 0 11.6556 11.0123 10.5378 11.7662 11.3957 12.9221 0 0 10.3489 11.2078 12.209 0 10.9471 11.2192 11.5261 12.0243 11.8881 11.4157 12.2971 12.5071 11.9288 P02549 SPTA1_HUMAN "Spectrin alpha chain, erythrocytic 1 (Erythroid alpha-spectrin)" SPTA1 SPTA Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament capping [GO:0051693]; actin filament organization [GO:0007015]; hemopoiesis [GO:0030097]; lymphocyte homeostasis [GO:0002260]; plasma membrane organization [GO:0007009]; porphyrin-containing compound biosynthetic process [GO:0006779]; positive regulation of protein binding [GO:0032092]; positive regulation of T cell proliferation [GO:0042102]; regulation of cell shape [GO:0008360] actin cytoskeleton [GO:0015629]; axon [GO:0030424]; cell junction [GO:0030054]; cell projection [GO:0042995]; cortical actin cytoskeleton [GO:0030864]; cuticular plate [GO:0032437]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; spectrin [GO:0008091]; spectrin-associated cytoskeleton [GO:0014731] actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; structural constituent of cytoskeleton [GO:0005200] 0.96914 -6.8133 GLALQRQK 0 0 10.3121 0 0 0 0 0 14.4306 9.12944 10.4324 9.16322 0 0 11.0266 10.8913 0 12.2378 0 0 9.57954 0 0 9.22069 0 0 0 P02647 APOA1_HUMAN Apolipoprotein A-I (Apo-AI) (ApoA-I) (Apolipoprotein A1) [Cleaved into: Proapolipoprotein A-I (ProapoA-I); Truncated apolipoprotein A-I (Apolipoprotein A-I(1-242))] APOA1 Homo sapiens (Human) adrenal gland development [GO:0030325]; blood vessel endothelial cell migration [GO:0043534]; cholesterol biosynthetic process [GO:0006695]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol import [GO:0070508]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; endothelial cell proliferation [GO:0001935]; G protein-coupled receptor signaling pathway [GO:0007186]; glucocorticoid metabolic process [GO:0008211]; high-density lipoprotein particle assembly [GO:0034380]; high-density lipoprotein particle clearance [GO:0034384]; high-density lipoprotein particle remodeling [GO:0034375]; integrin-mediated signaling pathway [GO:0007229]; lipid storage [GO:0019915]; lipoprotein biosynthetic process [GO:0042158]; negative chemotaxis [GO:0050919]; negative regulation of cell adhesion molecule production [GO:0060354]; negative regulation of cytokine production involved in immune response [GO:0002719]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of hydrolase activity [GO:0051346]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of response to cytokine stimulus [GO:0060761]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of very-low-density lipoprotein particle remodeling [GO:0010903]; peptidyl-methionine modification [GO:0018206]; phosphatidylcholine biosynthetic process [GO:0006656]; phosphatidylcholine metabolic process [GO:0046470]; phospholipid efflux [GO:0033700]; phospholipid homeostasis [GO:0055091]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cholesterol metabolic process [GO:0090205]; positive regulation of CoA-transferase activity [GO:1905920]; positive regulation of hydrolase activity [GO:0051345]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phospholipid efflux [GO:1902995]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein oxidation [GO:0018158]; protein stabilization [GO:0050821]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of intestinal cholesterol absorption [GO:0030300]; regulation of protein phosphorylation [GO:0001932]; reverse cholesterol transport [GO:0043691]; triglyceride homeostasis [GO:0070328]; vitamin transport [GO:0051180] blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endocytic vesicle lumen [GO:0071682]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; high-density lipoprotein particle [GO:0034364]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; spherical high-density lipoprotein particle [GO:0034366]; very-low-density lipoprotein particle [GO:0034361] amyloid-beta binding [GO:0001540]; apolipoprotein A-I receptor binding [GO:0034191]; apolipoprotein receptor binding [GO:0034190]; chemorepellent activity [GO:0045499]; cholesterol binding [GO:0015485]; cholesterol transfer activity [GO:0120020]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; high-density lipoprotein particle binding [GO:0008035]; high-density lipoprotein particle receptor binding [GO:0070653]; identical protein binding [GO:0042802]; phosphatidylcholine-sterol O-acyltransferase activator activity [GO:0060228]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102] 0.95361 -1.4998 LSPLGEEMRDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7284 0 0 P02656 APOC3_HUMAN Apolipoprotein C-III (Apo-CIII) (ApoC-III) (Apolipoprotein C3) APOC3 Homo sapiens (Human) cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; chylomicron remnant clearance [GO:0034382]; G protein-coupled receptor signaling pathway [GO:0007186]; high-density lipoprotein particle remodeling [GO:0034375]; lipoprotein metabolic process [GO:0042157]; negative regulation of cholesterol import [GO:0060621]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of high-density lipoprotein particle clearance [GO:0010987]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of lipoprotein lipase activity [GO:0051005]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of receptor-mediated endocytosis [GO:0048261]; negative regulation of triglyceride catabolic process [GO:0010897]; negative regulation of very-low-density lipoprotein particle clearance [GO:0010916]; negative regulation of very-low-density lipoprotein particle remodeling [GO:0010903]; phospholipid efflux [GO:0033700]; regulation of Cdc42 protein signal transduction [GO:0032489]; reverse cholesterol transport [GO:0043691]; triglyceride catabolic process [GO:0019433]; triglyceride homeostasis [GO:0070328]; triglyceride metabolic process [GO:0006641]; very-low-density lipoprotein particle assembly [GO:0034379] chylomicron [GO:0042627]; collagen-containing extracellular matrix [GO:0062023]; early endosome [GO:0005769]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate-density lipoprotein particle [GO:0034363]; spherical high-density lipoprotein particle [GO:0034366]; very-low-density lipoprotein particle [GO:0034361] cholesterol binding [GO:0015485]; enzyme regulator activity [GO:0030234]; high-density lipoprotein particle receptor binding [GO:0070653]; lipase inhibitor activity [GO:0055102]; phospholipid binding [GO:0005543] 0.93217 -1.2681 DYWSTVKDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.35337 0 0 0 0 0 0 0 P02671 FIBA_HUMAN Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain] FGA Homo sapiens (Human) "adaptive immune response [GO:0002250]; blood coagulation, common pathway [GO:0072377]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; fibrinolysis [GO:0042730]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; negative regulation of blood coagulation, common pathway [GO:2000261]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; protein polymerization [GO:0051258]; protein-containing complex assembly [GO:0065003]; response to calcium ion [GO:0051592]" blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093] extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198] 0.96911 -3.4818 ALAREVDLK 11.3033 9.87857 8.89942 0 0 0 0 10.8081 9.82736 0 9.91477 9.89306 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P02679 FIBG_HUMAN Fibrinogen gamma chain FGG PRO2061 Homo sapiens (Human) "blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; protein-containing complex assembly [GO:0065003]; response to calcium ion [GO:0051592]" blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093] cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198] 0 3.0426 TRWYSMKK 0 0 0 0 0 0 0 9.21201 9.32843 0 0 0 9.69615 0 0 9.14532 0 0 8.71139 9.08895 0 0 0 8.88295 0 0 8.7896 P02708 ACHA_HUMAN Acetylcholine receptor subunit alpha CHRNA1 ACHRA CHNRA Homo sapiens (Human) acetylcholine receptor signaling pathway [GO:0095500]; chemical synaptic transmission [GO:0007268]; monoatomic ion transmembrane transport [GO:0034220]; muscle cell cellular homeostasis [GO:0046716]; musculoskeletal movement [GO:0050881]; nervous system process [GO:0050877]; neuromuscular junction development [GO:0007528]; neuromuscular process [GO:0050905]; neuromuscular synaptic transmission [GO:0007274]; neuron cellular homeostasis [GO:0070050]; neuronal action potential [GO:0019228]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165]; skeletal muscle contraction [GO:0003009]; skeletal muscle tissue growth [GO:0048630] acetylcholine-gated channel complex [GO:0005892]; cell surface [GO:0009986]; neuromuscular junction [GO:0031594]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; postsynaptic specialization membrane [GO:0099634]; synapse [GO:0045202] acetylcholine binding [GO:0042166]; acetylcholine receptor activity [GO:0015464]; acetylcholine-gated monoatomic cation-selective channel activity [GO:0022848]; monoatomic ion channel activity [GO:0005216]; transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315] 0.80254 0.23782 QQWVDYNLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.37897 0 0 0 0 0 P02748 CO9_HUMAN Complement component C9 [Cleaved into: Complement component C9a; Complement component C9b] C9 Homo sapiens (Human) "cell killing [GO:0001906]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; killing of cells of another organism [GO:0031640]; positive regulation of immune response [GO:0050778]; protein homooligomerization [GO:0051260]" blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]; other organism cell membrane [GO:0044218]; plasma membrane [GO:0005886] 0.60452 0.4376 ALPTTYEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.226 0 0 0 0 0 0 0 0 P02751 FINC_HUMAN Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3] FN1 FN Homo sapiens (Human) "acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; biological process involved in interaction with symbiont [GO:0051702]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; cell-substrate junction assembly [GO:0007044]; endodermal cell differentiation [GO:0035987]; heart development [GO:0007507]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of monocyte activation [GO:0150102]; negative regulation of transforming growth factor beta production [GO:0071635]; nervous system development [GO:0007399]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; wound healing [GO:0042060]" apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093] collagen binding [GO:0005518]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102] 0.87079 0.057248 HHPEHFSGRPR 9.47798 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.52274 10.7825 0 0 9.94037 P02763 A1AG1_HUMAN Alpha-1-acid glycoprotein 1 (AGP 1) (Orosomucoid-1) (OMD 1) ORM1 AGP1 Homo sapiens (Human) acute-phase response [GO:0006953]; inflammatory response [GO:0006954]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of immune system process [GO:0002682] blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; platelet alpha granule lumen [GO:0031093]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724] 0.57256 0.48082 QDQCIYNTTYLNVQR 0 15.5044 14.1656 0 12.7322 0 13.7154 14.0448 14.0779 0 0 13.8924 0 0 12.8823 12.8799 13.4637 0 0 0 0 10.4711 0 0 0 0 0 P02765 FETUA_HUMAN Alpha-2-HS-glycoprotein (Alpha-2-Z-globulin) (Ba-alpha-2-glycoprotein) (Fetuin-A) [Cleaved into: Alpha-2-HS-glycoprotein chain A; Alpha-2-HS-glycoprotein chain B] AHSG FETUA PRO2743 Homo sapiens (Human) acute-phase response [GO:0006953]; negative regulation of bone mineralization [GO:0030502]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of insulin receptor signaling pathway [GO:0046627]; ossification [GO:0001503]; pinocytosis [GO:0006907]; positive regulation of phagocytosis [GO:0050766]; regulation of bone mineralization [GO:0030500]; regulation of inflammatory response [GO:0050727]; skeletal system development [GO:0001501] blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; platelet alpha granule lumen [GO:0031093]; secretory granule lumen [GO:0034774] cysteine-type endopeptidase inhibitor activity [GO:0004869]; endopeptidase inhibitor activity [GO:0004866]; kinase inhibitor activity [GO:0019210] 0 12.77 CDSSPDSAEDVR 0 0 0 0 0 0 0 0 0 10.0182 10.483 9.25538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P02768 ALBU_HUMAN Albumin ALB GIG20 GIG42 PRO0903 PRO1708 PRO2044 PRO2619 PRO2675 UNQ696/PRO1341 Homo sapiens (Human) cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; retina homeostasis [GO:0001895] blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991] antioxidant activity [GO:0016209]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; protein-folding chaperone binding [GO:0051087]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643] 0 163.03 AACLLPK 20.3456 20.2409 20.2462 17.2752 17.3861 17.6337 19.8621 20.1224 19.9468 19.9872 20.0552 20.1307 17.8345 17.8886 17.9377 18.6642 18.6731 18.365 14.6449 14.1656 14.2017 14.2157 14.029 13.9277 14.8687 14.1736 14.368 P02771 FETA_HUMAN Alpha-fetoprotein (Alpha-1-fetoprotein) (Alpha-fetoglobulin) AFP HPAFP Homo sapiens (Human) ovulation from ovarian follicle [GO:0001542]; progesterone metabolic process [GO:0042448]; SMAD protein signal transduction [GO:0060395] cytoplasm [GO:0005737]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615] metal ion binding [GO:0046872] 0.44799 0.6442 GYQELLEK 0 0 0 0 11.2485 0 0 0 0 9.95437 10.3306 9.72001 0 9.79515 0 0 0 0 0 0 0 0 0 0 0 0 0 P02776 PLF4_HUMAN "Platelet factor 4 (PF-4) (C-X-C motif chemokine 4) (Iroplact) (Oncostatin-A) [Cleaved into: Platelet factor 4, short form (Endothelial cell growth inhibitor)]" PF4 CXCL4 SCYB4 Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; cytokine-mediated signaling pathway [GO:0019221]; defense response to protozoan [GO:0042832]; inflammatory response [GO:0006954]; killing by host of symbiont cells [GO:0051873]; killing of cells of another organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; negative regulation of angiogenesis [GO:0016525]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of MHC class II biosynthetic process [GO:0045347]; neutrophil chemotaxis [GO:0030593]; platelet activation [GO:0030168]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell population proliferation [GO:0042127] collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; platelet alpha granule lumen [GO:0031093] chemokine activity [GO:0008009]; CXCR chemokine receptor binding [GO:0045236]; CXCR3 chemokine receptor binding [GO:0048248]; heparin binding [GO:0008201] 0.94636 -1.352 IIKKLLES 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.13906 0 0 0 P02786 TFR1_HUMAN "Transferrin receptor protein 1 (TR) (TfR) (TfR1) (Trfr) (T9) (p90) (CD antigen CD71) [Cleaved into: Transferrin receptor protein 1, serum form (sTfR)]" TFRC Homo sapiens (Human) acute-phase response [GO:0006953]; aging [GO:0007568]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to xenobiotic stimulus [GO:0071466]; intracellular iron ion homeostasis [GO:0006879]; intracellular signal transduction [GO:0035556]; iron ion transport [GO:0006826]; negative regulation of apoptotic process [GO:0043066]; negative regulation of mitochondrial fusion [GO:0010637]; osteoclast differentiation [GO:0030316]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of bone resorption [GO:0045780]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of isotype switching [GO:0045830]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein-containing complex assembly [GO:0031334]; positive regulation of T cell proliferation [GO:0042102]; receptor internalization [GO:0031623]; response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]; response to iron ion [GO:0010039]; response to manganese ion [GO:0010042]; response to nutrient [GO:0007584]; response to retinoic acid [GO:0032526]; transferrin transport [GO:0033572]; transport across blood-brain barrier [GO:0150104] basolateral plasma membrane [GO:0016323]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; clathrin-coated pit [GO:0005905]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endosome [GO:0005768]; endosome membrane [GO:0010008]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; HFE-transferrin receptor complex [GO:1990712]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038] double-stranded RNA binding [GO:0003725]; Hsp70 protein binding [GO:0030544]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; transferrin receptor activity [GO:0004998]; virus receptor activity [GO:0001618] 0.092453 1.2007 AAAEVAGQFVIK 0 10.6353 10.7175 0 0 0 9.26576 10.6989 10.0039 11.0106 11.0713 11.1248 0 0 0 0 0 0 0 0 9.42375 0 0 0 0 0 11.9238 P02787 TRFE_HUMAN Serotransferrin (Transferrin) (Beta-1 metal-binding globulin) (Siderophilin) TF PRO1400 Homo sapiens (Human) actin filament organization [GO:0007015]; antibacterial humoral response [GO:0019731]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; intracellular iron ion homeostasis [GO:0006879]; iron ion transmembrane transport [GO:0034755]; iron ion transport [GO:0006826]; osteoclast differentiation [GO:0030316]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of phosphorylation [GO:0042327]; positive regulation of receptor-mediated endocytosis [GO:0048260]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395] apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; clathrin-coated pit [GO:0005905]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982] ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459] 0 45.719 APNHAVVTR 12.4905 12.5465 12.2961 0 0 0 11.7136 12.0792 11.5497 11.7766 11.2838 12.627 0 10.0682 0 10.0972 10.0007 0 9.56073 0 10.1122 9.21038 0 0 0 0 9.2066 P02788 TRFL_HUMAN Lactotransferrin (Lactoferrin) (EC 3.4.21.-) (Growth-inhibiting protein 12) (Talalactoferrin) [Cleaved into: Lactoferricin-H (Lfcin-H); Kaliocin-1; Lactoferroxin-A; Lactoferroxin-B; Lactoferroxin-C] LTF GIG12 LF Homo sapiens (Human) antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; bone morphogenesis [GO:0060349]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; disruption by host of symbiont membrane [GO:0052337]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; iron ion transmembrane transport [GO:0034755]; iron ion transport [GO:0006826]; killing of cells of another organism [GO:0031640]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATP-dependent activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; proteolysis [GO:0006508]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895] cell surface [GO:0009986]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; phagocytic vesicle lumen [GO:0097013]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724] cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252] 0 7.0948 CGLVPVLAENYK 0 0 0 0 0 0 0 0 0 11.4345 11.824 11.4713 9.58763 9.74918 9.92793 10.7832 10.5951 10.8836 0 0 0 0 0 0 0 0 0 P02792 FRIL_HUMAN Ferritin light chain (Ferritin L subunit) FTL Homo sapiens (Human) intracellular iron ion homeostasis [GO:0006879]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826] autolysosome [GO:0044754]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; intracellular ferritin complex [GO:0008043]; membrane [GO:0016020] ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506] 0.16474 0.98596 KPAEDEWGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.98854 0 0 0 10.4175 0 0 0 0 0 10.4725 P02794 FRIH_HUMAN "Ferritin heavy chain (Ferritin H subunit) (EC 1.16.3.1) (Cell proliferation-inducing gene 15 protein) [Cleaved into: Ferritin heavy chain, N-terminally processed]" FTH1 FTH FTHL6 OK/SW-cl.84 PIG15 Homo sapiens (Human) immune response [GO:0006955]; intracellular iron ion homeostasis [GO:0006879]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147] autolysosome [GO:0044754]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724] ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; iron ion sequestering activity [GO:0140315] 0 9.3023 IFLQDIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.91854 0 8.94325 8.84455 8.72843 8.85019 8.95861 8.46434 8.85655 P03372 ESR1_HUMAN Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1) ESR1 ESR NR3A1 Homo sapiens (Human) androgen metabolic process [GO:0008209]; antral ovarian follicle growth [GO:0001547]; cellular response to estradiol stimulus [GO:0071392]; cellular response to estrogen stimulus [GO:0071391]; chromatin remodeling [GO:0006338]; epithelial cell development [GO:0002064]; epithelial cell proliferation involved in mammary gland duct elongation [GO:0060750]; fibroblast proliferation [GO:0048144]; intracellular estrogen receptor signaling pathway [GO:0030520]; intracellular steroid hormone receptor signaling pathway [GO:0030518]; male gonad development [GO:0008584]; mammary gland alveolus development [GO:0060749]; mammary gland branching involved in pregnancy [GO:0060745]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of gene expression [GO:0010629]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of miRNA transcription [GO:1902894]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of transcription by RNA polymerase II [GO:0045944]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; protein localization to chromatin [GO:0071168]; regulation of branching involved in prostate gland morphogenesis [GO:0060687]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell apoptotic process [GO:1904035]; regulation of inflammatory response [GO:0050727]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; RNA polymerase II preinitiation complex assembly [GO:0051123]; signal transduction [GO:0007165]; stem cell differentiation [GO:0048863]; steroid hormone mediated signaling pathway [GO:0043401]; uterus development [GO:0060065]; vagina development [GO:0060068] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; transcription regulator complex [GO:0005667] "14-3-3 protein binding [GO:0071889]; ATPase binding [GO:0051117]; beta-catenin binding [GO:0008013]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; estrogen response element binding [GO:0034056]; G protein-coupled estrogen receptor activity [GO:0038054]; identical protein binding [GO:0042802]; nitric-oxide synthase regulator activity [GO:0030235]; nuclear estrogen receptor activity [GO:0030284]; nuclear estrogen receptor binding [GO:0030331]; nuclear receptor activity [GO:0004879]; protein kinase binding [GO:0019901]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]; steroid binding [GO:0005496]; TBP-class protein binding [GO:0017025]; TFIIB-class transcription factor binding [GO:0001093]; transcription coactivator binding [GO:0001223]; transcription coregulator binding [GO:0001221]; transcription corepressor binding [GO:0001222]; zinc ion binding [GO:0008270]" 0.88272 -0.090137 AANLWPSPLMIKR 10.2264 0 15.404 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P03951 FA11_HUMAN Coagulation factor XI (FXI) (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) [Cleaved into: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain] F11 Homo sapiens (Human) "blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]" extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; serine-type endopeptidase complex [GO:1905370] heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252] 0.8835 -0.11923 ALSGFSLQSCR 0 0 0 0 0 0 0 0 10.0452 0 0 10.0979 0 0 0 0 0 0 0 0 0 0 0 9.25061 0 0 0 P03952 KLKB1_HUMAN Plasma kallikrein (EC 3.4.21.34) (Fletcher factor) (Kininogenin) (Plasma prekallikrein) (PKK) [Cleaved into: Plasma kallikrein heavy chain; Plasma kallikrein light chain] KLKB1 KLK3 Homo sapiens (Human) "blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; Factor XII activation [GO:0002542]; fibrinolysis [GO:0042730]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]" extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; serine-type endopeptidase complex [GO:1905370] serine-type endopeptidase activity [GO:0004252] 0.89762 -0.62705 CQFFTYSLLPEDCK 12.085 11.4285 0 0 11.5047 0 0 0 10.7221 0 10.6342 13.2814 12.0006 0 12.3389 0 0 0 0 0 0 0 0 0 0 0 0 P03956 MMP1_HUMAN Interstitial collagenase (EC 3.4.24.7) (Fibroblast collagenase) (Matrix metalloproteinase-1) (MMP-1) [Cleaved into: 22 kDa interstitial collagenase; 27 kDa interstitial collagenase] MMP1 CLG Homo sapiens (Human) cellular response to UV-A [GO:0071492]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; positive regulation of protein-containing complex assembly [GO:0031334]; protein metabolic process [GO:0019538]; proteolysis [GO:0006508] extracellular matrix [GO:0031012]; extracellular region [GO:0005576] endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270] 0.76685 0.27817 WEQTHLTYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0485 0 9.95723 P03999 OPSB_HUMAN Short-wave-sensitive opsin 1 (Blue cone photoreceptor pigment) (Blue-sensitive opsin) (BOP) OPN1SW BCP Homo sapiens (Human) cellular response to UV-A [GO:0071492]; G protein-coupled receptor signaling pathway [GO:0007186]; phototransduction [GO:0007602]; signal transduction [GO:0007165]; visual perception [GO:0007601] cone photoreceptor outer segment [GO:0120199]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor disc membrane [GO:0097381]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; photoreceptor activity [GO:0009881]; signaling receptor activity [GO:0038023] 0.87623 -0.001411 SEEEFYLFK 0 0 0 0 0 0 0 0 0 9.23132 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P04003 C4BPA_HUMAN C4b-binding protein alpha chain (C4bp) (Proline-rich protein) (PRP) C4BPA C4BP Homo sapiens (Human) "complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation of complement activation, classical pathway [GO:0045959]; positive regulation of protein catabolic process [GO:0045732]; regulation of opsonization [GO:1903027]; response to symbiotic bacterium [GO:0009609]; T cell mediated immunity [GO:0002456]" blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] RNA binding [GO:0003723] 0.8989 -0.63793 MAAWPFSR 0 0 0 0 0 0 0 0 0 0 0 9.66455 0 0 0 0 0 0 0 0 9.96175 0 0 0 0 0 0 P04035 HMDH_HUMAN 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) (EC 1.1.1.34) HMGCR Homo sapiens (Human) cholesterol biosynthetic process [GO:0006695]; coenzyme A metabolic process [GO:0015936]; isoprenoid biosynthetic process [GO:0008299]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein secretion [GO:0050709]; sterol biosynthetic process [GO:0016126]; visual learning [GO:0008542] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; peroxisomal membrane [GO:0005778] coenzyme A binding [GO:0120225]; hydroxymethylglutaryl-CoA reductase (NADPH) activity [GO:0004420]; NADPH binding [GO:0070402] 0.9274 -1.2057 LHEYFPEMQILAVSGNYCTDK 0 0 0 0 0 0 0 0 10.0345 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P04040 CATA_HUMAN Catalase (EC 1.11.1.6) CAT Homo sapiens (Human) aerobic respiration [GO:0009060]; aging [GO:0007568]; cellular detoxification of hydrogen peroxide [GO:0061692]; cellular response to growth factor stimulus [GO:0071363]; cholesterol metabolic process [GO:0008203]; hemoglobin metabolic process [GO:0020027]; hydrogen peroxide catabolic process [GO:0042744]; negative regulation of apoptotic process [GO:0043066]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; osteoblast differentiation [GO:0001649]; positive regulation of cell division [GO:0051781]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; response to activity [GO:0014823]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to fatty acid [GO:0070542]; response to hydrogen peroxide [GO:0042542]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to inactivity [GO:0014854]; response to insulin [GO:0032868]; response to L-ascorbic acid [GO:0033591]; response to lead ion [GO:0010288]; response to light intensity [GO:0009642]; response to ozone [GO:0010193]; response to phenylpropanoid [GO:0080184]; response to reactive oxygen species [GO:0000302]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to xenobiotic stimulus [GO:0009410]; triglyceride metabolic process [GO:0006641]; ureteric bud development [GO:0001657]; UV protection [GO:0009650] catalase complex [GO:0062151]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; membrane [GO:0016020]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774] "aminoacylase activity [GO:0004046]; antioxidant activity [GO:0016209]; catalase activity [GO:0004096]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; protein homodimerization activity [GO:0042803]" 0.75967 0.30213 DLFNAIATGK 0 0 0 0 0 0 0 0 0 9.18321 9.39836 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P04049 RAF1_HUMAN RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1) RAF1 RAF Homo sapiens (Human) activation of adenylate cyclase activity [GO:0007190]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; death-inducing signaling complex assembly [GO:0071550]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; face development [GO:0060324]; insulin receptor signaling pathway [GO:0008286]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; insulin-like growth factor receptor signaling pathway [GO:0048009]; intermediate filament cytoskeleton organization [GO:0045104]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of protein-containing complex assembly [GO:0031333]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of cell differentiation [GO:0045595]; regulation of cell motility [GO:2000145]; regulation of Rho protein signal transduction [GO:0035023]; response to muscle stretch [GO:0035994]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; type B pancreatic cell proliferation [GO:0044342]; wound healing [GO:0042060] cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143] ATP binding [GO:0005524]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; MAP kinase kinase kinase activity [GO:0004709]; metal ion binding [GO:0046872]; protein kinase activator activity [GO:0030295]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.94598 -1.35 HLHVQETK 18.1614 0 0 0 0 0 0 0 0 0 0 9.70907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P04066 FUCO_HUMAN Tissue alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucosidase I) (Alpha-L-fucoside fucohydrolase 1) (Alpha-L-fucosidase 1) FUCA1 Nbla10230 Homo sapiens (Human) fucose metabolic process [GO:0006004]; glycolipid catabolic process [GO:0019377]; glycosaminoglycan catabolic process [GO:0006027]; glycoside catabolic process [GO:0016139] azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764] alpha-L-fucosidase activity [GO:0004560] 0.19279 0.93303 DGLIVPIFQER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3305 0 0 0 0 P04070 PROC_HUMAN Vitamin K-dependent protein C (EC 3.4.21.69) (Anticoagulant protein C) (Autoprothrombin IIA) (Blood coagulation factor XIV) [Cleaved into: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide] PROC Homo sapiens (Human) blood coagulation [GO:0007596]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood coagulation [GO:0030195]; negative regulation of coagulation [GO:0050819]; negative regulation of inflammatory response [GO:0050728]; positive regulation of establishment of endothelial barrier [GO:1903142]; proteolysis [GO:0006508] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi lumen [GO:0005796]; serine-type endopeptidase complex [GO:1905370] calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252] 0.95314 -1.5011 WEKWELDLDIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.92753 11.3357 11.3304 0 0 0 0 0 0 0 0 0 0 P04075 ALDOA_HUMAN Fructose-bisphosphate aldolase A (EC 4.1.2.13) (Lung cancer antigen NY-LU-1) (Muscle-type aldolase) ALDOA ALDA Homo sapiens (Human) "actin filament organization [GO:0007015]; ATP biosynthetic process [GO:0006754]; binding of sperm to zona pellucida [GO:0007339]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose metabolic process [GO:0006000]; glycolytic process [GO:0006096]; muscle cell cellular homeostasis [GO:0046716]; protein homotetramerization [GO:0051289]; regulation of cell shape [GO:0008360]; striated muscle contraction [GO:0006941]" actin cytoskeleton [GO:0015629]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; I band [GO:0031674]; M band [GO:0031430]; membrane [GO:0016020]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; secretory granule lumen [GO:0034774]; sperm head [GO:0061827]; tertiary granule lumen [GO:1904724] actin binding [GO:0003779]; cadherin binding [GO:0045296]; cytoskeletal protein binding [GO:0008092]; fructose binding [GO:0070061]; fructose-bisphosphate aldolase activity [GO:0004332]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; tubulin binding [GO:0015631] 0 184.34 AAQEEYVK 12.1273 12.3092 12.2253 0 8.80093 0 13.0233 13.429 13.7946 14.5349 14.2205 14.2464 13.9738 14.2326 14.2353 14.4065 14.3002 13.9316 13.8508 13.6218 13.8108 13.0968 13.6614 13.2812 14.9943 14.7787 14.3744 P04080 CYTB_HUMAN Cystatin-B (CPI-B) (Liver thiol proteinase inhibitor) (Stefin-B) CSTB CST6 STFB Homo sapiens (Human) adult locomotory behavior [GO:0008344]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861] collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleolus [GO:0005730]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724] cysteine-type endopeptidase inhibitor activity [GO:0004869]; endopeptidase inhibitor activity [GO:0004866]; protease binding [GO:0002020]; RNA binding [GO:0003723] 0 36.921 AKHDELTYF 0 0 0 0 0 0 8.75442 9.23007 9.32865 0 11.1775 11.0888 11.5246 10.8117 10.4568 0 11.411 11.0678 9.5404 0 0 10.3467 0 9.41553 0 10.6216 0 P04083 ANXA1_HUMAN Annexin A1 (Annexin I) (Annexin-1) (Calpactin II) (Calpactin-2) (Chromobindin-9) (Lipocortin I) (Phospholipase A2 inhibitory protein) (p35) [Cleaved into: Annexin Ac2-26] ANXA1 ANX1 LPC1 Homo sapiens (Human) "actin cytoskeleton reorganization [GO:0031532]; adaptive immune response [GO:0002250]; alpha-beta T cell differentiation [GO:0046632]; arachidonic acid secretion [GO:0050482]; cell surface receptor signaling pathway [GO:0007166]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; DNA duplex unwinding [GO:0032508]; endocrine pancreas development [GO:0031018]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gliogenesis [GO:0042063]; granulocyte chemotaxis [GO:0071621]; hepatocyte differentiation [GO:0070365]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; insulin secretion [GO:0030073]; keratinocyte differentiation [GO:0030216]; localization [GO:0051179]; monocyte chemotaxis [GO:0002548]; myoblast migration involved in skeletal muscle regeneration [GO:0014839]; negative regulation of apoptotic process [GO:0043066]; negative regulation of exocytosis [GO:0045920]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of phospholipase A2 activity [GO:1900138]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; neutrophil activation [GO:0042119]; neutrophil clearance [GO:0097350]; neutrophil homeostasis [GO:0001780]; peptide cross-linking [GO:0018149]; phagocytosis [GO:0006909]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell differentiation [GO:0045627]; positive regulation of vesicle fusion [GO:0031340]; positive regulation of wound healing [GO:0090303]; prolactin secretion [GO:0070459]; prostate gland development [GO:0030850]; regulation of cell shape [GO:0008360]; regulation of hormone secretion [GO:0046883]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-1 production [GO:0032652]; regulation of leukocyte migration [GO:0002685]; response to estradiol [GO:0032355]; response to interleukin-1 [GO:0070555]; response to peptide hormone [GO:0043434]; response to X-ray [GO:0010165]; signal transduction [GO:0007165]" adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; extrinsic component of membrane [GO:0019898]; focal adhesion [GO:0005925]; lateral plasma membrane [GO:0016328]; motile cilium [GO:0031514]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; vesicle [GO:0031982] cadherin binding involved in cell-cell adhesion [GO:0098641]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; lipid binding [GO:0008289]; phospholipase A2 inhibitor activity [GO:0019834]; phospholipid binding [GO:0005543]; signaling receptor binding [GO:0005102] 0 103.14 ALYEAGER 9.64528 11.1859 10.6202 0 0 0 0 9.79922 0 0 10.2966 9.39272 0 0 8.98507 0 0 0 0 0 0 0 0 0 0 0 0 P04085 PDGFA_HUMAN Platelet-derived growth factor subunit A (PDGF subunit A) (PDGF-1) (Platelet-derived growth factor A chain) (Platelet-derived growth factor alpha polypeptide) PDGFA PDGF1 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; cell activation [GO:0001775]; cell projection assembly [GO:0030031]; cell-cell signaling [GO:0007267]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic lung development [GO:1990401]; hair follicle development [GO:0001942]; inner ear development [GO:0048839]; lung alveolus development [GO:0048286]; male gonad development [GO:0008584]; negative chemotaxis [GO:0050919]; negative regulation of phosphatidylinositol biosynthetic process [GO:0010512]; negative regulation of platelet activation [GO:0010544]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; platelet-derived growth factor receptor-alpha signaling pathway [GO:0035790]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway [GO:0035793]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling [GO:0060683]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of smooth muscle cell migration [GO:0014910]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to inorganic substance [GO:0010035]; response to retinoic acid [GO:0032526]; response to wounding [GO:0009611]; response to xenobiotic stimulus [GO:0009410]; skin development [GO:0043588]; wound healing [GO:0042060] cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; microvillus [GO:0005902]; platelet alpha granule lumen [GO:0031093]; platelet-derived growth factor complex [GO:1990265] collagen binding [GO:0005518]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; platelet-derived growth factor binding [GO:0048407]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803] 0.95909 -1.7161 EVIERLAR 0 0 0 0 9.70577 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P04114 APOB_HUMAN Apolipoprotein B-100 (Apo B-100) [Cleaved into: Apolipoprotein B-48 (Apo B-48)] APOB Homo sapiens (Human) artery morphogenesis [GO:0048844]; cellular response to prostaglandin stimulus [GO:0071379]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; establishment of localization in cell [GO:0051649]; fertilization [GO:0009566]; flagellated sperm motility [GO:0030317]; in utero embryonic development [GO:0001701]; lipoprotein biosynthetic process [GO:0042158]; lipoprotein catabolic process [GO:0042159]; lipoprotein transport [GO:0042953]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle remodeling [GO:0034374]; nervous system development [GO:0007399]; positive regulation of cholesterol storage [GO:0010886]; positive regulation of gene expression [GO:0010628]; positive regulation of lipid storage [GO:0010884]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; post-embryonic development [GO:0009791]; regulation of cholesterol biosynthetic process [GO:0045540]; response to carbohydrate [GO:0009743]; response to estradiol [GO:0032355]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; response to virus [GO:0009615]; spermatogenesis [GO:0007283]; triglyceride catabolic process [GO:0019433]; triglyceride mobilization [GO:0006642]; very-low-density lipoprotein particle assembly [GO:0034379] chylomicron [GO:0042627]; chylomicron remnant [GO:0034360]; clathrin-coated endocytic vesicle membrane [GO:0030669]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endocytic vesicle lumen [GO:0071682]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endosome lumen [GO:0031904]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; high-density lipoprotein particle [GO:0034364]; intermediate-density lipoprotein particle [GO:0034363]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; low-density lipoprotein particle [GO:0034362]; lysosomal lumen [GO:0043202]; mature chylomicron [GO:0034359]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; smooth endoplasmic reticulum [GO:0005790]; very-low-density lipoprotein particle [GO:0034361]; vesicle lumen [GO:0031983] cholesterol transfer activity [GO:0120020]; heparin binding [GO:0008201]; lipase binding [GO:0035473]; low-density lipoprotein particle receptor binding [GO:0050750]; phospholipid binding [GO:0005543] 0.96236 -2.542 AGHIAWTSSGKGSWK 10.2601 0 9.88414 0 9.6706 0 10.0028 0 9.90742 0 0 0 0 0 0 14.5077 0 0 0 0 0 9.36514 0 0 12.1461 12.6617 11.1996 P04179 SODM_HUMAN "Superoxide dismutase [Mn], mitochondrial (EC 1.15.1.1)" SOD2 Homo sapiens (Human) acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; aging [GO:0007568]; cellular response to ethanol [GO:0071361]; cellular response to oxidative stress [GO:0034599]; detection of oxygen [GO:0003032]; erythrophore differentiation [GO:0048773]; glutathione metabolic process [GO:0006749]; heart development [GO:0007507]; hemopoiesis [GO:0030097]; hydrogen peroxide biosynthetic process [GO:0050665]; intracellular oxygen homeostasis [GO:0032364]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; multicellular organismal-level iron ion homeostasis [GO:0060586]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of membrane hyperpolarization [GO:1902631]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; neuron development [GO:0048666]; positive regulation of cell migration [GO:0030335]; positive regulation of hydrogen peroxide biosynthetic process [GO:0010729]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; post-embryonic development [GO:0009791]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of catalytic activity [GO:0050790]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; respiratory electron transport chain [GO:0022904]; response to activity [GO:0014823]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to electrical stimulus [GO:0051602]; response to gamma radiation [GO:0010332]; response to hydrogen peroxide [GO:0042542]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to immobilization stress [GO:0035902]; response to isolation stress [GO:0035900]; response to L-ascorbic acid [GO:0033591]; response to lipopolysaccharide [GO:0032496]; response to magnetism [GO:0071000]; response to manganese ion [GO:0010042]; response to selenium ion [GO:0010269]; response to silicon dioxide [GO:0034021]; response to superoxide [GO:0000303]; response to xenobiotic stimulus [GO:0009410]; response to zinc ion [GO:0010043]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801] extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739] DNA binding [GO:0003677]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; oxygen binding [GO:0019825]; superoxide dismutase activity [GO:0004784] 0 21.032 GDVTAQIALQPALK 0 0 0 0 0 0 0 0 0 10.789 10.5055 10.6484 10.8495 10.8456 10.9717 11.0539 11.7248 10.8927 0 0 0 0 0 0 0 0 0 P04181 OAT_HUMAN "Ornithine aminotransferase, mitochondrial (EC 2.6.1.13) (Ornithine delta-aminotransferase) (Ornithine--oxo-acid aminotransferase) [Cleaved into: Ornithine aminotransferase, hepatic form; Ornithine aminotransferase, renal form]" OAT Homo sapiens (Human) arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to proline via ornithine [GO:0010121]; L-proline biosynthetic process [GO:0055129]; visual perception [GO:0007601] cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] identical protein binding [GO:0042802]; ornithine(lysine) transaminase activity [GO:0050155]; ornithine-oxo-acid transaminase activity [GO:0004587]; pyridoxal phosphate binding [GO:0030170] 0.084291 1.2274 IVFAAGNFWGR 0 0 0 0 0 0 9.28983 9.28626 9.24203 0 0 8.86227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P04196 HRG_HUMAN Histidine-rich glycoprotein (Histidine-proline-rich glycoprotein) (HPRG) HRG Homo sapiens (Human) angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; chemotaxis [GO:0006935]; cytolysis by host of symbiont cells [GO:0051838]; defense response to fungus [GO:0050832]; fibrinolysis [GO:0042730]; heme transport [GO:0015886]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of lamellipodium assembly [GO:0010593]; negative regulation of vascular endothelial growth factor signaling pathway [GO:1900747]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel remodeling [GO:2000504]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of immune response to tumor cell [GO:0002839]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of blood coagulation [GO:0030193]; regulation of gene expression [GO:0010468]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of platelet activation [GO:0010543]; regulation of protein-containing complex assembly [GO:0043254] blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endolysosome [GO:0036019]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093] cysteine-type endopeptidase inhibitor activity [GO:0004869]; heme binding [GO:0020037]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; immunoglobulin binding [GO:0019865]; metal ion binding [GO:0046872]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor binding [GO:0005102]; zinc ion binding [GO:0008270] 0.95121 -1.4 GPGKGPRPFHCRQIGSVYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2476 0 0 0 0 0 0 0 0 0 0 0 0 P04234 CD3D_HUMAN T-cell surface glycoprotein CD3 delta chain (T-cell receptor T3 delta chain) (CD antigen CD3d) CD3D T3D Homo sapiens (Human) adaptive immune response [GO:0002250]; alpha-beta T cell activation [GO:0046631]; cell surface receptor signaling pathway [GO:0007166]; positive thymic T cell selection [GO:0045059]; T cell receptor signaling pathway [GO:0050852] alpha-beta T cell receptor complex [GO:0042105]; clathrin-coated endocytic vesicle membrane [GO:0030669]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101] identical protein binding [GO:0042802]; transmembrane signaling receptor activity [GO:0004888] 0.81192 0.22253 LSGAADTQALLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.05688 0 0 0 0 0 P04259 K2C6B_HUMAN "Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK-6B) (Keratin-6B) (K6B) (Type-II keratin Kb10)" KRT6B K6B KRTL1 Homo sapiens (Human) ectoderm development [GO:0007398]; keratinization [GO:0031424] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; keratin filament [GO:0045095] structural constituent of cytoskeleton [GO:0005200]; structural constituent of skin epidermis [GO:0030280] 0 25.311 ADTLTDEINFLR 9.14473 9.08855 9.89964 0 0 0 10.3244 8.67037 10.5618 0 0 0 0 0 9.88431 0 10.725 9.16262 0 10.2564 0 0 0 0 0 0 0 P04264 K2C1_HUMAN "Keratin, type II cytoskeletal 1 (67 kDa cytokeratin) (Cytokeratin-1) (CK-1) (Hair alpha protein) (Keratin-1) (K1) (Type-II keratin Kb1)" KRT1 KRTA Homo sapiens (Human) "complement activation, lectin pathway [GO:0001867]; establishment of skin barrier [GO:0061436]; fibrinolysis [GO:0042730]; keratinization [GO:0031424]; negative regulation of inflammatory response [GO:0050728]; peptide cross-linking [GO:0018149]; protein heterotetramerization [GO:0051290]; regulation of angiogenesis [GO:0045765]; response to oxidative stress [GO:0006979]; retina homeostasis [GO:0001895]" blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; keratin filament [GO:0045095]; membrane [GO:0016020]; nucleus [GO:0005634] carbohydrate binding [GO:0030246]; protein heterodimerization activity [GO:0046982]; signaling receptor activity [GO:0038023]; structural constituent of skin epidermis [GO:0030280] 0 323.31 AEAESLYQSK 16.2319 16.0931 16.1439 12.587 12.8087 12.1905 16.0136 16.1609 16.1258 16.2764 16.1275 16.2508 14.3176 14.157 14.2035 15.6164 15.7323 15.4262 14.447 14.2214 14.9835 13.5824 14.0781 14.0501 15.1614 15.1001 14.4378 P04275 VWF_HUMAN von Willebrand factor (vWF) [Cleaved into: von Willebrand antigen 2 (von Willebrand antigen II)] VWF F8VWF Homo sapiens (Human) blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; positive regulation of intracellular signal transduction [GO:1902533]; response to wounding [GO:0009611] collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093] collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein-folding chaperone binding [GO:0051087] 0.89036 -0.50121 AFVVDMMER 8.74957 0 0 0 0 9.35154 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.64241 0 P04278 SHBG_HUMAN Sex hormone-binding globulin (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estradiol-binding globulin) (TeBG) (Testosterone-estrogen-binding globulin) SHBG Homo sapiens (Human) extracellular exosome [GO:0070062]; extracellular region [GO:0005576] androgen binding [GO:0005497]; steroid binding [GO:0005496] 0.96912 -3.3761 WHQVEVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.10559 0 0 0 0 P04406 G3P_HUMAN Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12) (Peptidyl-cysteine S-nitrosylase GAPDH) (EC 2.6.99.-) GAPDH GAPD CDABP0047 OK/SW-cl.12 Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular response to type II interferon [GO:0071346]; defense response to fungus [GO:0050832]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; killing by host of symbiont cells [GO:0051873]; killing of cells of another organism [GO:0031640]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of translation [GO:0017148]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation of cytokine production [GO:0001819]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of type I interferon production [GO:0032481]; protein stabilization [GO:0050821]; regulation of macroautophagy [GO:0016241] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; GAIT complex [GO:0097452]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982] aspartic-type endopeptidase inhibitor activity [GO:0019828]; disordered domain specific binding [GO:0097718]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; peptidyl-cysteine S-nitrosylase activity [GO:0035605] 0 135.24 AENGKLVINGNPITIFQER 13.2705 13.1636 12.9791 11.1436 11.7107 11.5315 13.9399 13.9555 13.8604 14.1269 14.3105 14.4208 14.2895 14.3744 14.4426 14.3988 14.7876 14.3086 14.7322 14.4575 14.4908 14.2322 14.2743 14.4756 15.7733 15.659 15.781 P04626 ERBB2_HUMAN Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340) ERBB2 HER2 MLN19 NEU NGL Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme-linked receptor protein signaling pathway [GO:0007167]; ERBB2-EGFR signaling pathway [GO:0038134]; ERBB2-ERBB3 signaling pathway [GO:0038133]; ERBB2-ERBB4 signaling pathway [GO:0038135]; heart development [GO:0007507]; immature T cell proliferation in thymus [GO:0033080]; intracellular signal transduction [GO:0035556]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neurogenesis [GO:0022008]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; oligodendrocyte differentiation [GO:0048709]; peptidyl-tyrosine phosphorylation [GO:0018108]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; ERBB3:ERBB2 complex [GO:0038143]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuromuscular junction [GO:0031594]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587] ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888] 0.91591 -0.77584 GQECVEECRVLQGLPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5228 0 0 0 0 0 0 0 0 0 0 0 P04628 WNT1_HUMAN Proto-oncogene Wnt-1 (Proto-oncogene Int-1 homolog) WNT1 INT1 Homo sapiens (Human) animal organ regeneration [GO:0031100]; astrocyte-dopaminergic neuron signaling [GO:0036520]; bone development [GO:0060348]; branching involved in ureteric bud morphogenesis [GO:0001658]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904954]; cell fate commitment [GO:0045165]; cell proliferation in midbrain [GO:0033278]; cell-cell signaling [GO:0007267]; cellular response to peptide hormone stimulus [GO:0071375]; central nervous system morphogenesis [GO:0021551]; cerebellum formation [GO:0021588]; diencephalon development [GO:0021536]; embryonic axis specification [GO:0000578]; embryonic brain development [GO:1990403]; fat cell differentiation [GO:0045444]; forebrain anterior/posterior pattern specification [GO:0021797]; hematopoietic stem cell proliferation [GO:0071425]; hepatocyte differentiation [GO:0070365]; inner ear morphogenesis [GO:0042472]; midbrain development [GO:0030901]; midbrain-hindbrain boundary maturation during brain development [GO:0022004]; myoblast fusion [GO:0007520]; negative regulation of apoptotic process [GO:0043066]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cellular senescence [GO:2000773]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; neuron differentiation [GO:0030182]; neuron fate determination [GO:0048664]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of dermatome development [GO:0061184]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to wounding [GO:0009611]; signal transduction in response to DNA damage [GO:0042770]; Spemann organizer formation [GO:0060061]; spinal cord association neuron differentiation [GO:0021527]; T cell differentiation in thymus [GO:0033077]; ubiquitin-dependent SMAD protein catabolic process [GO:0030579]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953] cell surface [GO:0009986]; cytoplasm [GO:0005737]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886] cytokine activity [GO:0005125]; frizzled binding [GO:0005109]; morphogen activity [GO:0016015]; protein domain specific binding [GO:0019904]; receptor ligand activity [GO:0048018] 0.91592 -0.77305 CHGMSGSCTVR 0 0 0 0 0 0 0 0 10.3969 0 0 11.0073 0 0 0 9.10182 11.388 0 0 0 0 0 0 0 0 0 0 P04629 NTRK1_HUMAN High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA) NTRK1 MTC TRK TRKA Homo sapiens (Human) "aging [GO:0007568]; axon guidance [GO:0007411]; axonogenesis involved in innervation [GO:0060385]; B cell differentiation [GO:0030183]; behavioral response to formalin induced pain [GO:0061368]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to nicotine [GO:0071316]; circadian rhythm [GO:0007623]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; learning or memory [GO:0007611]; mechanoreceptor differentiation [GO:0042490]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; nerve growth factor signaling pathway [GO:0038180]; neuron apoptotic process [GO:0051402]; neuron development [GO:0048666]; neuron projection development [GO:0031175]; neurotrophin TRK receptor signaling pathway [GO:0048011]; olfactory nerve development [GO:0021553]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of kinase activity [GO:0033674]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; programmed cell death involved in cell development [GO:0010623]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of protein kinase B signaling [GO:0051896]; response to axon injury [GO:0048678]; response to electrical stimulus [GO:0051602]; response to hydrostatic pressure [GO:0051599]; response to nutrient levels [GO:0031667]; response to radiation [GO:0009314]; response to xenobiotic stimulus [GO:0009410]; Sertoli cell development [GO:0060009]; sympathetic nervous system development [GO:0048485]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]" axon [GO:0030424]; cell surface [GO:0009986]; dendrite [GO:0030425]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome membrane [GO:0055038] ATP binding [GO:0005524]; GPI-linked ephrin receptor activity [GO:0005004]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; nerve growth factor binding [GO:0048406]; nerve growth factor receptor activity [GO:0010465]; neurotrophin binding [GO:0043121]; neurotrophin p75 receptor binding [GO:0005166]; neurotrophin receptor activity [GO:0005030]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714] 0.87086 0.03371 WMPPESILYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2209 0 0 0 0 0 0 0 0 0 P04632 CPNS1_HUMAN Calpain small subunit 1 (CSS1) (Calcium-activated neutral proteinase small subunit) (CANP small subunit) (Calcium-dependent protease small subunit) (CDPS) (Calcium-dependent protease small subunit 1) (Calpain regulatory subunit) CAPNS1 CAPN4 CAPNS Homo sapiens (Human) positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; regulation of macroautophagy [GO:0016241] calpain complex [GO:0110158]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198] 0 10.25 MFLVNSFLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.01137 0 0 8.24921 8.62143 8.89673 9.01606 8.95559 P04792 HSPB1_HUMAN Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27) HSPB1 HSP27 HSP28 Homo sapiens (Human) anterograde axonal protein transport [GO:0099641]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chaperone-mediated protein folding [GO:0061077]; intracellular signal transduction [GO:0035556]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein kinase activity [GO:0006469]; platelet aggregation [GO:0070527]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of autophagy [GO:0010506]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of protein phosphorylation [GO:0001932]; regulation of translational initiation [GO:0006446]; response to unfolded protein [GO:0006986]; response to virus [GO:0009615]; retina homeostasis [GO:0001895] axon cytoplasm [GO:1904115]; cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; spindle [GO:0005819]; Z disc [GO:0030018] identical protein binding [GO:0042802]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein kinase C binding [GO:0005080]; protein kinase C inhibitor activity [GO:0008426]; RNA binding [GO:0003723]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; ubiquitin binding [GO:0043130] 0 49.645 AQLGGPEAAK 12.1648 12.1133 11.1563 9.42909 16.7098 16.6188 12.2035 11.2441 11.1862 13.8115 12.6623 13.7107 12.7835 13.0377 12.869 12.8167 14.0494 13.1467 10.1135 11.0522 11.691 0 0 0 10.7308 9.20203 0 P04839 CY24B_HUMAN Cytochrome b-245 heavy chain (EC 1.-.-.-) (CGD91-phox) (Cytochrome b(558) subunit beta) (Cytochrome b558 subunit beta) (Heme-binding membrane glycoprotein gp91phox) (NADPH oxidase 2) (Neutrophil cytochrome b 91 kDa polypeptide) (Superoxide-generating NADPH oxidase heavy chain subunit) (gp91-1) (gp91-phox) (p22 phagocyte B-cytochrome) CYBB NOX2 Homo sapiens (Human) cellular response to cadmium ion [GO:0071276]; cellular response to ethanol [GO:0071361]; cellular response to L-glutamine [GO:1904845]; defense response [GO:0006952]; electron transport chain [GO:0022900]; hydrogen peroxide biosynthetic process [GO:0050665]; hypoxia-inducible factor-1alpha signaling pathway [GO:0097411]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; positive regulation of angiogenesis [GO:0045766]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of monoatomic ion transmembrane transport [GO:0034765]; respiratory burst [GO:0045730]; response to aldosterone [GO:1904044]; response to angiotensin [GO:1990776]; response to nutrient [GO:0007584]; response to xenobiotic stimulus [GO:0009410]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801] dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; NADPH oxidase complex [GO:0043020]; neuronal cell body [GO:0043025]; nuclear envelope [GO:0005635]; perinuclear endoplasmic reticulum [GO:0097038]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821] flavin adenine dinucleotide binding [GO:0050660]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; superoxide-generating NAD(P)H oxidase activity [GO:0016175]; voltage-gated monoatomic ion channel activity [GO:0005244] 0.4232 0.66707 IYFYWLCR 0 0 0 0 0 0 0 0 0 0 9.74465 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P04843 RPN1_HUMAN Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit) (Ribophorin I) (RPN-I) (Ribophorin-1) RPN1 Homo sapiens (Human) protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; melanosome [GO:0042470]; membrane [GO:0016020]; oligosaccharyltransferase complex [GO:0008250]; rough endoplasmic reticulum [GO:0005791] RNA binding [GO:0003723] 0 33.273 ALTSEIALLQSR 10.3949 9.39124 9.75377 0 0 0 10.468 10.472 10.4484 0 9.30747 0 0 8.92751 8.90683 10.4912 11.0514 9.71272 10.5167 10.5114 9.34012 11.0039 11.6309 10.5394 12.5817 12.4655 11.8494 P04844 RPN2_HUMAN Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit) (RIBIIR) (Ribophorin II) (RPN-II) (Ribophorin-2) RPN2 Homo sapiens (Human) aging [GO:0007568]; protein modification process [GO:0036211]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]; response to xenobiotic stimulus [GO:0009410] autophagosome membrane [GO:0000421]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; nuclear body [GO:0016604]; oligosaccharyltransferase complex [GO:0008250]; rough endoplasmic reticulum [GO:0005791] ribosome binding [GO:0043022] 0.80133 0.24154 MLAQQAVK 0 0 0 0 0 0 0 0 0 11.7607 0 11.3629 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P04920 B3A2_HUMAN Anion exchange protein 2 (AE 2) (Anion exchanger 2) (Non-erythroid band 3-like protein) (BND3L) (Solute carrier family 4 member 2) SLC4A2 AE2 EPB3L1 HKB3 MPB3L Homo sapiens (Human) "amelogenesis [GO:0097186]; bicarbonate transport [GO:0015701]; digestive tract development [GO:0048565]; monoatomic anion transport [GO:0006820]; negative regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043377]; negative regulation of CD8-positive, alpha-beta T cell proliferation [GO:2000565]; osteoclast differentiation [GO:0030316]; positive regulation of enamel mineralization [GO:0070175]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of bone resorption [GO:0045124]; regulation of intracellular pH [GO:0051453]; spermatogenesis [GO:0007283]; transmembrane transport [GO:0055085]" apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; focal adhesion [GO:0005925]; membrane [GO:0016020]; plasma membrane [GO:0005886] chloride:bicarbonate antiporter activity [GO:0140900]; enzyme binding [GO:0019899]; monoatomic anion transmembrane transporter activity [GO:0008509]; solute:inorganic anion antiporter activity [GO:0005452]; transmembrane transporter activity [GO:0022857] 0.96949 -3.5828 GGEEPGR 0 0 0 0 0 0 0 8.7807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.55278 9.66274 P05000 IFNW1_HUMAN Interferon omega-1 (Interferon alpha-II-1) IFNW1 Homo sapiens (Human) adaptive immune response [GO:0002250]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; cellular response to virus [GO:0098586]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; natural killer cell activation involved in immune response [GO:0002323]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; regulation of cell cycle [GO:0051726]; response to exogenous dsRNA [GO:0043330]; response to virus [GO:0009615]; T cell activation involved in immune response [GO:0002286]; type I interferon-mediated signaling pathway [GO:0060337] extracellular space [GO:0005615] cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; type I interferon receptor binding [GO:0005132] 0.91335 -0.82131 RISPFLCLK 0 0 0 0 0 0 0 0 8.8752 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P05015 IFN16_HUMAN Interferon alpha-16 (IFN-alpha-16) (Interferon alpha-WA) IFNA16 Homo sapiens (Human) adaptive immune response [GO:0002250]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; cellular response to virus [GO:0098586]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; natural killer cell activation involved in immune response [GO:0002323]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon-mediated signaling pathway [GO:0060337] extracellular region [GO:0005576]; extracellular space [GO:0005615] cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132] 0.59451 0.44663 ISHFSCLK 10.399 0 10.3791 0 0 0 0 10.6466 0 0 10.4683 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P05023 AT1A1_HUMAN Sodium/potassium-transporting ATPase subunit alpha-1 (Na(+)/K(+) ATPase alpha-1 subunit) (EC 7.2.2.13) (Sodium pump subunit alpha-1) ATP1A1 Homo sapiens (Human) cardiac muscle cell action potential involved in contraction [GO:0086002]; cell communication by electrical coupling involved in cardiac conduction [GO:0086064]; cellular response to steroid hormone stimulus [GO:0071383]; establishment or maintenance of transmembrane electrochemical gradient [GO:0010248]; intracellular potassium ion homeostasis [GO:0030007]; intracellular sodium ion homeostasis [GO:0006883]; membrane repolarization [GO:0086009]; membrane repolarization during cardiac muscle cell action potential [GO:0086013]; negative regulation of glucocorticoid biosynthetic process [GO:0031947]; negative regulation of heart contraction [GO:0045822]; positive regulation of heart contraction [GO:0045823]; positive regulation of striated muscle contraction [GO:0045989]; potassium ion import across plasma membrane [GO:1990573]; proton transmembrane transport [GO:1902600]; regulation of blood pressure [GO:0008217]; regulation of sodium ion transport [GO:0002028]; regulation of the force of heart contraction [GO:0002026]; relaxation of cardiac muscle [GO:0055119]; response to glycoside [GO:1903416]; response to xenobiotic stimulus [GO:0009410]; sodium ion export across plasma membrane [GO:0036376] apical plasma membrane [GO:0016324]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular vesicle [GO:1903561]; Golgi apparatus [GO:0005794]; lateral plasma membrane [GO:0016328]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; organelle membrane [GO:0031090]; photoreceptor inner segment membrane [GO:0060342]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; sodium:potassium-exchanging ATPase complex [GO:0005890]; sperm flagellum [GO:0036126]; T-tubule [GO:0030315] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; P-type sodium:potassium-exchanging transporter activity [GO:0005391]; phosphatase activity [GO:0016791]; potassium ion binding [GO:0030955]; protein heterodimerization activity [GO:0046982]; protein-folding chaperone binding [GO:0051087]; sodium ion binding [GO:0031402]; steroid hormone binding [GO:1990239] 0 11.412 AVAGDASESALLK 0 0 8.50184 0 0 0 10.2684 10.3839 10.1763 0 0 13.6847 0 9.79515 0 0 0 10.043 10.2211 11.3299 0 11.2492 11.2508 12.1779 12.6025 12.1047 12.1241 P05060 SCG1_HUMAN Secretogranin-1 (Chromogranin-B) (CgB) (Secretogranin I) (SgI) [Cleaved into: PE-11; GAWK peptide; CCB peptide] CHGB SCG1 Homo sapiens (Human) endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; secretory granule [GO:0030141] hormone activity [GO:0005179] 0.96854 -3.6097 AYFMSDTREEKR 0 0 0 0 0 0 0 0 0 0 0 8.50518 9.80587 0 0 0 0 0 8.77709 0 0 0 10.4756 0 0 0 0 P05067 A4_HUMAN Amyloid-beta precursor protein (APP) (ABPP) (APPI) (Alzheimer disease amyloid A4 protein homolog) (Alzheimer disease amyloid protein) (Amyloid precursor protein) (Amyloid-beta (A4) precursor protein) (Amyloid-beta A4 protein) (Cerebral vascular amyloid peptide) (CVAP) (PreA4) (Protease nexin-II) (PN-II) [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (Beta-secretase C-terminal fragment) (Beta-CTF); Amyloid-beta protein 42 (Abeta42) (Beta-APP42); Amyloid-beta protein 40 (Abeta40) (Beta-APP40); C83 (Alpha-secretase C-terminal fragment) (Alpha-CTF); P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59 (Amyloid intracellular domain 59) (AICD-59) (AID(59)) (Gamma-CTF(59)); Gamma-secretase C-terminal fragment 57 (Amyloid intracellular domain 57) (AICD-57) (AID(57)) (Gamma-CTF(57)); Gamma-secretase C-terminal fragment 50 (Amyloid intracellular domain 50) (AICD-50) (AID(50)) (Gamma-CTF(50)); C31] APP A4 AD1 Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; associative learning [GO:0008306]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; central nervous system development [GO:0007417]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; G2/M transition of mitotic cell cycle [GO:0000086]; innate immune response [GO:0045087]; intracellular copper ion homeostasis [GO:0006878]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; lipoprotein metabolic process [GO:0042157]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of blood circulation [GO:1903523]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of miRNA transcription [GO:1902894]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of peptidase activity [GO:0010466]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of Wnt signaling pathway [GO:0030178]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron cellular homeostasis [GO:0070050]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of apoptotic process [GO:0043065]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell activation [GO:0050867]; positive regulation of chemokine production [GO:0032722]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelin production [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of histone acetylation [GO:0035066]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic depression [GO:1900454]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import [GO:1904591]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor binding [GO:1900122]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of T cell migration [GO:2000406]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type II interferon production [GO:0032729]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; protein trimerization [GO:0070206]; regulation of acetylcholine-gated cation channel activity [GO:1903048]; regulation of amyloid fibril formation [GO:1905906]; regulation of amyloid-beta clearance [GO:1900221]; regulation of dendritic spine maintenance [GO:1902950]; regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903381]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of gene expression [GO:0010468]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of MAPK cascade [GO:0043408]; regulation of multicellular organism growth [GO:0040014]; regulation of NMDA receptor activity [GO:2000310]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of presynapse assembly [GO:1905606]; regulation of protein tyrosine kinase activity [GO:0061097]; regulation of response to calcium ion [GO:1905945]; regulation of signaling receptor activity [GO:0010469]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; regulation of Wnt signaling pathway [GO:0030111]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; visual learning [GO:0008542] amyloid-beta complex [GO:0106003]; apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome lumen [GO:0031904]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi lumen [GO:0005796]; Golgi-associated vesicle [GO:0005798]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; high-density lipoprotein particle [GO:0034364]; intermediate-density lipoprotein particle [GO:0034363]; lipoprotein particle [GO:1990777]; main axon [GO:0044304]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; neuronal dense core vesicle [GO:0098992]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588] acetylcholine receptor activator activity [GO:0030549]; acetylcholine receptor binding [GO:0033130]; amylin binding [GO:0097645]; apolipoprotein binding [GO:0034185]; chemoattractant activity [GO:0042056]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; frizzled binding [GO:0005109]; G protein-coupled receptor binding [GO:0001664]; growth factor receptor binding [GO:0070851]; heparan sulfate binding [GO:1904399]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein-folding chaperone binding [GO:0051087]; PTB domain binding [GO:0051425]; RAGE receptor binding [GO:0050786]; receptor ligand activity [GO:0048018]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; signaling receptor binding [GO:0005102]; transition metal ion binding [GO:0046914] 0.89789 -0.56364 KQCKTHPHFVIPYR 0 0 0 0 0 0 0 0 0 0 0 0 8.95026 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P05091 ALDH2_HUMAN "Aldehyde dehydrogenase, mitochondrial (EC 1.2.1.3) (ALDH class 2) (ALDH-E2) (ALDHI)" ALDH2 ALDM Homo sapiens (Human) alcohol metabolic process [GO:0006066]; aldehyde catabolic process [GO:0046185]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; regulation of dopamine biosynthetic process [GO:1903179]; regulation of serotonin biosynthetic process [GO:1905627] extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; carboxylesterase activity [GO:0106435]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; nitroglycerin reductase activity [GO:0018547]; phenylacetaldehyde dehydrogenase activity [GO:0008957] 0.96262 -2.0823 EEIFGPVMQILKFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.72574 0 0 0 0 0 0 P05107 ITB2_HUMAN "Integrin beta-2 (Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD antigen CD18)" ITGB2 CD18 MFI7 Homo sapiens (Human) "amyloid-beta clearance [GO:0097242]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell-cell signaling [GO:0007267]; cell-matrix adhesion [GO:0007160]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; endodermal cell differentiation [GO:0035987]; heterotypic cell-cell adhesion [GO:0034113]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil chemotaxis [GO:0030593]; neutrophil migration [GO:1990266]; phagocytosis, engulfment [GO:0006911]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor clustering [GO:0043113]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of cell shape [GO:0008360]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]" cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular vesicle [GO:1903561]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; integrin alphaL-beta2 complex [GO:0034687]; integrin alphaM-beta2 complex [GO:0034688]; integrin alphaX-beta2 complex [GO:0034689]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821] amyloid-beta binding [GO:0001540]; cell adhesion molecule binding [GO:0050839]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; ICAM-3 receptor activity [GO:0030369]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901] 0.92405 -1.0296 ALGFTDIVTVQVLPQCECR 9.57211 9.61099 0 0 0 0 0 0 9.45331 8.81279 0 0 0 0 0 0 0 0 0 0 0 0 11.4316 0 0 0 0 P05109 S10A8_HUMAN Protein S100-A8 (Calgranulin-A) (Calprotectin L1L subunit) (Cystic fibrosis antigen) (CFAG) (Leukocyte L1 complex light chain) (Migration inhibitory factor-related protein 8) (MRP-8) (p8) (S100 calcium-binding protein A8) (Urinary stone protein band A) S100A8 CAGA CFAG MRP8 Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chronic inflammatory response [GO:0002544]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; peptide secretion [GO:0002790]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; wound healing [GO:0042060] collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774] arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270] 0 10.235 GADVWFK 0 0 0 0 0 0 0 0 0 11.9848 12.4713 12.1616 11.6654 11.9904 11.8213 12.747 12.2336 12.2101 0 0 8.77877 0 8.90361 0 10.0847 0 9.39855 P05121 PAI1_HUMAN Plasminogen activator inhibitor 1 (PAI) (PAI-1) (Endothelial plasminogen activator inhibitor) (Serpin E1) SERPINE1 PAI1 PLANH1 Homo sapiens (Human) angiogenesis [GO:0001525]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-negative bacterium [GO:0050829]; dentinogenesis [GO:0097187]; fibrinolysis [GO:0042730]; negative regulation of blood coagulation [GO:0030195]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cell migration [GO:0030336]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of plasminogen activation [GO:0010757]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of smooth muscle cell-matrix adhesion [GO:2000098]; negative regulation of vascular wound healing [GO:0061044]; negative regulation of wound healing [GO:0061045]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood coagulation [GO:0030194]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of leukotriene production involved in inflammatory response [GO:0035491]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of odontoblast differentiation [GO:1901331]; positive regulation of receptor-mediated endocytosis [GO:0048260]; regulation of signaling receptor activity [GO:0010469]; replicative senescence [GO:0090399] collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; peptidase inhibitor complex [GO:1904090]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; serine protease inhibitor complex [GO:0097180] protease binding [GO:0002020]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor binding [GO:0005102] 0.89034 -0.4816 LVQGFMPHFFRLFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5971 0 0 0 P05141 ADT2_HUMAN "ADP/ATP translocase 2 (ADP,ATP carrier protein 2) (ADP,ATP carrier protein, fibroblast isoform) (Adenine nucleotide translocator 2) (ANT 2) (Solute carrier family 25 member 5) [Cleaved into: ADP/ATP translocase 2, N-terminally processed]" SLC25A5 AAC2 ANT2 Homo sapiens (Human) adaptive thermogenesis [GO:1990845]; adenine nucleotide transport [GO:0051503]; B cell differentiation [GO:0030183]; cellular response to leukemia inhibitory factor [GO:1990830]; chromosome segregation [GO:0007059]; erythrocyte differentiation [GO:0030218]; mitochondrial ADP transmembrane transport [GO:0140021]; mitochondrial ATP transmembrane transport [GO:1990544]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of mitophagy [GO:1901526]; regulation of mitochondrial membrane permeability [GO:0046902] membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial nucleoid [GO:0042645]; mitochondrial permeability transition pore complex [GO:0005757]; mitochondrion [GO:0005739]; MMXD complex [GO:0071817]; nucleus [GO:0005634]; plasma membrane [GO:0005886] adenine nucleotide transmembrane transporter activity [GO:0000295]; adenine transmembrane transporter activity [GO:0015207]; ATP:ADP antiporter activity [GO:0005471]; oxidative phosphorylation uncoupler activity [GO:0017077]; proton transmembrane transporter activity [GO:0015078]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625] 0 70.314 AAYFGIYDTAK 10.7401 10.1384 10.8508 0 0 0 11.4744 12.0443 12.2328 11.6535 11.2412 10.9767 10.7476 9.99732 10.4715 9.93202 11.972 11.6146 11.1704 11.7399 11.6694 11.5351 10.4164 12.0603 12.3227 12.3625 12.752 P05155 IC1_HUMAN Plasma protease C1 inhibitor (C1 Inh) (C1Inh) (C1 esterase inhibitor) (C1-inhibiting factor) (Serpin G1) SERPING1 C1IN C1NH Homo sapiens (Human) "aging [GO:0007568]; blood circulation [GO:0008015]; blood coagulation [GO:0007596]; complement activation, classical pathway [GO:0006958]; fibrinolysis [GO:0042730]; innate immune response [GO:0045087]; negative regulation of complement activation, lectin pathway [GO:0001869]; negative regulation of endopeptidase activity [GO:0010951]" blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; platelet alpha granule lumen [GO:0031093] serine-type endopeptidase inhibitor activity [GO:0004867] 0.95966 -1.8607 GVTSVSQIFHSPDLAIR 0 9.46414 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7755 0 0 0 0 0 0 0 0 0 0 P05156 CFAI_HUMAN Complement factor I (EC 3.4.21.45) (C3B/C4B inactivator) [Cleaved into: Complement factor I heavy chain; Complement factor I light chain] CFI IF Homo sapiens (Human) "complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; proteolysis [GO:0006508]; regulation of complement activation, alternative pathway [GO:0030451]" extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; serine-type endopeptidase complex [GO:1905370] metal ion binding [GO:0046872]; scavenger receptor activity [GO:0005044]; serine-type endopeptidase activity [GO:0004252] 0.96013 -1.7931 GLETSLAECTFTKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.8365 0 0 9.90743 0 0 0 0 0 8.65632 0 P05160 F13B_HUMAN Coagulation factor XIII B chain (Fibrin-stabilizing factor B subunit) (Protein-glutamine gamma-glutamyltransferase B chain) (Transglutaminase B chain) F13B Homo sapiens (Human) "blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; peptide cross-linking [GO:0018149]" extracellular region [GO:0005576]; extracellular space [GO:0005615]; transferase complex [GO:1990234] 0.96992 -3.0813 ISRCEQGK 0 0 9.92031 0 0 0 0 0 0 0 0 0 0 0 0 0 8.80161 0 0 0 0 0 0 0 0 0 0 P05161 ISG15_HUMAN Ubiquitin-like protein ISG15 (Interferon-induced 15 kDa protein) (Interferon-induced 17 kDa protein) (IP17) (Ubiquitin cross-reactive protein) (hUCRP) ISG15 G1P2 UCRP Homo sapiens (Human) defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of type II interferon production [GO:0032729]; protein localization to mitochondrion [GO:0070585]; regulation of type II interferon production [GO:0032649]; response to type I interferon [GO:0034340]; response to virus [GO:0009615] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654] integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625] 0.95437 -1.5282 AQITQKIGVHAFQQR 0 0 0 0 0 0 0 0 0 0 9.63196 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P05164 PERM_HUMAN Myeloperoxidase (MPO) (EC 1.11.2.2) [Cleaved into: Myeloperoxidase; 89 kDa myeloperoxidase; 84 kDa myeloperoxidase; Myeloperoxidase light chain; Myeloperoxidase heavy chain] MPO Homo sapiens (Human) aging [GO:0007568]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; hydrogen peroxide catabolic process [GO:0042744]; hypochlorous acid biosynthetic process [GO:0002149]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of apoptotic process [GO:0043066]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in defense response [GO:0002679]; response to food [GO:0032094]; response to gold nanoparticle [GO:1990268]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878] azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phagocytic vesicle lumen [GO:0097013]; secretory granule [GO:0030141] chromatin binding [GO:0003682]; heme binding [GO:0020037]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601] 0.8768 -0.0039084 GVPFFSSLR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.69561 0 0 0 0 0 0 0 0 0 0 0 0 0 P05165 PCCA_HUMAN "Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCase subunit alpha) (EC 6.4.1.3) (Propanoyl-CoA:carbon dioxide ligase subunit alpha)" PCCA Homo sapiens (Human) branched-chain amino acid metabolic process [GO:0009081]; fatty acid metabolic process [GO:0006631]; short-chain fatty acid catabolic process [GO:0019626] catalytic complex [GO:1902494]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; biotin binding [GO:0009374]; enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; propionyl-CoA carboxylase activity [GO:0004658] 0.8121 0.22423 ASAGGGGK 9.54898 0 0 0 0 0 0 7.97911 0 0 8.77946 0 0 0 0 9.08675 0 0 0 0 8.97951 0 0 0 10.7165 0 0 P05166 PCCB_HUMAN "Propionyl-CoA carboxylase beta chain, mitochondrial (PCCase subunit beta) (EC 6.4.1.3) (Propanoyl-CoA:carbon dioxide ligase subunit beta)" PCCB Homo sapiens (Human) branched-chain amino acid metabolic process [GO:0009081]; fatty acid metabolic process [GO:0006631]; short-chain fatty acid catabolic process [GO:0019626] catalytic complex [GO:1902494]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; propionyl-CoA carboxylase activity [GO:0004658] 0.5176 0.59857 DTSYLFITGPDVVK 0 9.788 0 0 0 0 0 11.4699 10.5381 0 9.69136 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5808 0 0 P05181 CP2E1_HUMAN Cytochrome P450 2E1 (EC 1.14.14.1) (4-nitrophenol 2-hydroxylase) (EC 1.14.13.n7) (CYPIIE1) (Cytochrome P450-J) CYP2E1 CYP2E Homo sapiens (Human) 4-nitrophenol metabolic process [GO:0018960]; benzene metabolic process [GO:0018910]; carbon tetrachloride metabolic process [GO:0018885]; epoxygenase P450 pathway [GO:0019373]; halogenated hydrocarbon metabolic process [GO:0042197]; heterocycle metabolic process [GO:0046483]; lipid hydroxylation [GO:0002933]; long-chain fatty acid biosynthetic process [GO:0042759]; long-chain fatty acid metabolic process [GO:0001676]; monoterpenoid metabolic process [GO:0016098]; response to bacterium [GO:0009617]; response to ethanol [GO:0045471]; response to organonitrogen compound [GO:0010243]; response to ozone [GO:0010193]; steroid metabolic process [GO:0008202]; triglyceride metabolic process [GO:0006641]; xenobiotic metabolic process [GO:0006805] cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial inner membrane [GO:0005743] "4-nitrophenol 2-monooxygenase activity [GO:0018601]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; iron ion binding [GO:0005506]; long-chain fatty acid omega-1 hydroxylase activity [GO:0120319]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; oxygen binding [GO:0019825]" 0.95991 -1.7264 AVKEALLDYK 0 0 0 0 0 0 0 0 0 0 0 9.7863 0 0 0 0 0 0 0 10.2146 0 0 0 0 0 0 0 P05186 PPBT_HUMAN "Alkaline phosphatase, tissue-nonspecific isozyme (AP-TNAP) (TNS-ALP) (TNSALP) (EC 3.1.3.1) (Alkaline phosphatase liver/bone/kidney isozyme) (Phosphoamidase) (Phosphocreatine phosphatase) (EC 3.9.1.1)" ALPL Homo sapiens (Human) bone mineralization [GO:0030282]; calcium ion homeostasis [GO:0055074]; cellular homeostasis [GO:0019725]; cellular response to organic cyclic compound [GO:0071407]; cementum mineralization [GO:0071529]; dephosphorylation [GO:0016311]; developmental process involved in reproduction [GO:0003006]; endochondral ossification [GO:0001958]; futile creatine cycle [GO:0140651]; inhibition of non-skeletal tissue mineralization [GO:0140928]; osteoblast differentiation [GO:0001649]; phosphate ion homeostasis [GO:0055062]; positive regulation of cold-induced thermogenesis [GO:0120162]; pyridoxal phosphate metabolic process [GO:0042822]; response to antibiotic [GO:0046677]; response to glucocorticoid [GO:0051384]; response to insulin [GO:0032868]; response to lipopolysaccharide [GO:0032496]; response to macrophage colony-stimulating factor [GO:0036005]; response to sodium phosphate [GO:1904383]; response to vitamin B6 [GO:0034516]; response to vitamin D [GO:0033280]; skeletal system development [GO:0001501] extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; membrane [GO:0016020]; mitochondrial intermembrane space [GO:0005758]; mitochondrial membrane [GO:0031966]; plasma membrane [GO:0005886] ADP phosphatase activity [GO:0043262]; alkaline phosphatase activity [GO:0004035]; ATP hydrolysis activity [GO:0016887]; calcium ion binding [GO:0005509]; inorganic diphosphate phosphatase activity [GO:0004427]; phosphoamidase activity [GO:0050187]; phosphoethanolamine phosphatase activity [GO:0052732]; pyridoxal phosphatase activity [GO:0033883]; pyrophosphatase activity [GO:0016462] 0.8086 0.22923 GQLHHNPGEETR 0 0 0 0 0 0 9.74325 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P05362 ICAM1_HUMAN Intercellular adhesion molecule 1 (ICAM-1) (Major group rhinovirus receptor) (CD antigen CD54) ICAM1 Homo sapiens (Human) adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cellular response to amyloid-beta [GO:1904646]; establishment of endothelial barrier [GO:0061028]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291] cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; membrane [GO:0016020]; plasma membrane [GO:0005886] integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618] 0.96335 -2.0894 DLEGTYLCRAR 9.83676 0 0 0 0 0 0 9.48277 0 0 0 0 11.8237 0 0 0 0 0 0 0 0 9.6037 0 0 10.7883 0 0 P05387 RLA2_HUMAN Large ribosomal subunit protein P2 (60S acidic ribosomal protein P2) (Renal carcinoma antigen NY-REN-44) RPLP2 D11S2243E RPP2 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; cytoplasmic translational elongation [GO:0002182]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020] structural constituent of ribosome [GO:0003735] 0.010101 1.8935 LASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEK 0 0 0 0 0 0 0 0 8.94729 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P05388 RLA0_HUMAN Large ribosomal subunit protein uL10 (60S acidic ribosomal protein P0) (60S ribosomal protein L10E) RPLP0 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412] cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; ribonucleoprotein complex [GO:1990904] large ribosomal subunit rRNA binding [GO:0070180]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0 29.089 AFLADPSAFVAAAPVAAATTAAPAAAAAPAK 0 0 0 0 0 0 10.4558 10.5297 10.2541 0 0 0 11.221 11.2388 10.3614 9.68464 9.96441 10.8323 11.0637 9.18148 10.2228 10.3535 10.3463 9.52258 10.6475 11.179 11.2013 P05412 JUN_HUMAN Transcription factor Jun (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39) JUN Homo sapiens (Human) angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; axon regeneration [GO:0031103]; cell population proliferation [GO:0008283]; cellular response to anisomycin [GO:0072740]; cellular response to cadmium ion [GO:0071276]; cellular response to calcium ion [GO:0071277]; cellular response to reactive oxygen species [GO:0034614]; eyelid development in camera-type eye [GO:0061029]; integrated stress response signaling [GO:0140467]; leading edge cell differentiation [GO:0035026]; liver development [GO:0001889]; microglial cell activation [GO:0001774]; monocyte differentiation [GO:0030224]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990441]; outflow tract morphogenesis [GO:0003151]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of DNA-templated transcription initiation [GO:2000144]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of transcription by RNA polymerase II [GO:0006357]; response to muscle stretch [GO:0035994]; response to xenobiotic stimulus [GO:0009410]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179] chromatin [GO:0000785]; euchromatin [GO:0000791]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575]; transcription factor AP-1 complex [GO:0035976]; transcription regulator complex [GO:0005667]; transcription repressor complex [GO:0017053] "cAMP response element binding [GO:0035497]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; general transcription initiation factor binding [GO:0140296]; GTPase activator activity [GO:0005096]; identical protein binding [GO:0042802]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]" 0.95427 -1.5344 IAASKCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.86423 9.15831 0 0 0 0 P05423 RPC4_HUMAN DNA-directed RNA polymerase III subunit RPC4 (RNA polymerase III subunit C4) (DNA-directed RNA polymerase III subunit D) (Protein BN51) (RNA polymerase III 47 kDa subunit) (RPC53 homolog) POLR3D BN51 BN51T Homo sapiens (Human) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728]; transcription by RNA polymerase III [GO:0006383] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; RNA polymerase III complex [GO:0005666] chromatin binding [GO:0003682]; DNA binding [GO:0003677] 0.84778 0.17033 KTPGLPK 10.506 10.5815 10.548 0 0 0 0 10.5777 10.6648 0 0 0 0 0 0 0 0 0 11.4397 11.5068 11.5796 0 0 0 0 0 0 P05455 LA_HUMAN Lupus La protein (La autoantigen) (La ribonucleoprotein) (Sjoegren syndrome type B antigen) (SS-B) SSB Homo sapiens (Human) histone mRNA metabolic process [GO:0008334]; IRES-dependent viral translational initiation [GO:0075522]; nuclear histone mRNA catabolic process [GO:0071045]; positive regulation of translation [GO:0045727]; protein localization to cytoplasmic stress granule [GO:1903608]; tRNA 3'-end processing [GO:0042780]; tRNA 5'-leader removal [GO:0001682]; tRNA export from nucleus [GO:0006409]; tRNA modification [GO:0006400]; tRNA processing [GO:0008033] "chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]" DNA binding [GO:0003677]; mRNA binding [GO:0003729]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; sequence-specific mRNA binding [GO:1990825]; tRNA binding [GO:0000049] 0.88906 -0.4388 DDYFAKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4117 0 9.40214 0 0 0 0 0 0 0 0 P05538 DQB2_HUMAN "HLA class II histocompatibility antigen, DQ beta 2 chain (HLA class II histocompatibility antigen, DX beta chain) (MHC class II antigen DQB2)" HLA-DQB2 HLA-DXB Homo sapiens (Human) adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; immune response [GO:0006955]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; positive regulation of T cell activation [GO:0050870] clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; lumenal side of endoplasmic reticulum membrane [GO:0098553]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658] MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395] 0.95517 -1.5207 GPRGPPPAGLLH 9.10148 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P05546 HEP2_HUMAN Heparin cofactor 2 (Heparin cofactor II) (HC-II) (Protease inhibitor leuserpin-2) (HLS2) (Serpin D1) SERPIND1 HCF2 Homo sapiens (Human) blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; negative regulation of endopeptidase activity [GO:0010951] endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615] endopeptidase inhibitor activity [GO:0004866]; heparin binding [GO:0008201]; serine-type endopeptidase inhibitor activity [GO:0004867] 0.87605 -0.0016119 DALENIDPATQMMILNCIYFK 9.98271 11.5985 9.11004 0 0 11.2161 0 0 0 0 0 0 0 0 0 0 0 8.50339 0 0 0 0 0 0 0 0 0 P05556 ITB1_HUMAN Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29) ITGB1 FNRB MDF2 MSK12 Homo sapiens (Human) "axon extension [GO:0048675]; B cell differentiation [GO:0030183]; basement membrane organization [GO:0071711]; calcium-independent cell-matrix adhesion [GO:0007161]; cardiac cell fate specification [GO:0060912]; cardiac muscle cell differentiation [GO:0055007]; cardiac muscle cell myoblast differentiation [GO:0060379]; CD40 signaling pathway [GO:0023035]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell projection organization [GO:0030030]; cell-cell adhesion mediated by integrin [GO:0033631]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; cellular defense response [GO:0006968]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; dendrite morphogenesis [GO:0048813]; establishment of mitotic spindle orientation [GO:0000132]; formation of radial glial scaffolds [GO:0021943]; G1/S transition of mitotic cell cycle [GO:0000082]; germ cell migration [GO:0008354]; heterotypic cell-cell adhesion [GO:0034113]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; integrin-mediated signaling pathway [GO:0007229]; lamellipodium assembly [GO:0030032]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte tethering or rolling [GO:0050901]; maintenance of blood-brain barrier [GO:0035633]; mesodermal cell differentiation [GO:0048333]; muscle organ development [GO:0007517]; myoblast differentiation [GO:0045445]; myoblast fate specification [GO:0048626]; myoblast fusion [GO:0007520]; negative regulation of anoikis [GO:2000811]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of Rho protein signal transduction [GO:0035024]; neuroblast proliferation [GO:0007405]; phagocytosis [GO:0006909]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of glutamate uptake involved in transmission of nerve impulse [GO:0051951]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of wound healing [GO:0090303]; reactive gliosis [GO:0150103]; receptor internalization [GO:0031623]; regulation of cell cycle [GO:0051726]; regulation of collagen catabolic process [GO:0010710]; regulation of inward rectifier potassium channel activity [GO:1901979]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse pruning [GO:1905806]; sarcomere organization [GO:0045214]; visual learning [GO:0008542]; wound healing, spreading of epidermal cells [GO:0035313]" cell surface [GO:0009986]; cerebellar climbing fiber to Purkinje cell synapse [GO:0150053]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; endosome membrane [GO:0010008]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; glial cell projection [GO:0097386]; integrin alpha1-beta1 complex [GO:0034665]; integrin alpha10-beta1 complex [GO:0034680]; integrin alpha11-beta1 complex [GO:0034681]; integrin alpha2-beta1 complex [GO:0034666]; integrin alpha3-beta1 complex [GO:0034667]; integrin alpha4-beta1 complex [GO:0034668]; integrin alpha5-beta1 complex [GO:0034674]; integrin alpha7-beta1 complex [GO:0034677]; integrin alpha8-beta1 complex [GO:0034678]; integrin complex [GO:0008305]; intercalated disc [GO:0014704]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; myelin sheath abaxonal region [GO:0035748]; neuromuscular junction [GO:0031594]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; Schaffer collateral - CA1 synapse [GO:0098685]; synaptic membrane [GO:0097060] actin binding [GO:0003779]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; collagen binding involved in cell-matrix adhesion [GO:0098639]; coreceptor activity [GO:0015026]; fibronectin binding [GO:0001968]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; magnesium ion binding [GO:0000287]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; protein tyrosine kinase binding [GO:1990782]; protein-containing complex binding [GO:0044877]; virus receptor activity [GO:0001618] 0.16555 0.99168 ITSDFRIGFGSFVEK 0 0 0 0 0 0 0 9.08036 9.36214 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P05771 KPCB_HUMAN Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13) PRKCB PKCB PRKCB1 Homo sapiens (Human) adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; B cell activation [GO:0042113]; B cell receptor signaling pathway [GO:0050853]; calcium ion transport [GO:0006816]; cellular response to carbohydrate stimulus [GO:0071322]; intracellular calcium ion homeostasis [GO:0006874]; intracellular signal transduction [GO:0035556]; lipoprotein transport [GO:0042953]; mitotic nuclear membrane disassembly [GO:0007077]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; peptidyl-serine phosphorylation [GO:0018105]; phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway [GO:0007207]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell receptor signaling pathway [GO:0050861]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of insulin secretion [GO:0032024]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; post-translational protein modification [GO:0043687]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein phosphorylation [GO:0006468]; regulation of glucose transmembrane transport [GO:0010827]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165] calyx of Held [GO:0044305]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; presynaptic cytosol [GO:0099523]; spectrin [GO:0008091] ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; calcium-dependent protein kinase C activity [GO:0004698]; chromatin binding [GO:0003682]; histone binding [GO:0042393]; histone H3T6 kinase activity [GO:0035403]; nuclear androgen receptor binding [GO:0050681]; nuclear receptor coactivator activity [GO:0030374]; protein kinase C activity [GO:0004697]; protein kinase C binding [GO:0005080]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; zinc ion binding [GO:0008270] 0.95594 -1.5467 ASVDGWFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3329 0 0 0 0 0 0 0 0 0 0 0 0 P05783 K1C18_HUMAN "Keratin, type I cytoskeletal 18 (Cell proliferation-inducing gene 46 protein) (Cytokeratin-18) (CK-18) (Keratin-18) (K18)" KRT18 CYK18 PIG46 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; cell cycle [GO:0007049]; extrinsic apoptotic signaling pathway [GO:0097191]; Golgi to plasma membrane protein transport [GO:0043001]; hepatocyte apoptotic process [GO:0097284]; intermediate filament cytoskeleton organization [GO:0045104]; negative regulation of apoptotic process [GO:0043066]; tumor necrosis factor-mediated signaling pathway [GO:0033209] adherens junction [GO:0005912]; cell periphery [GO:0071944]; centriolar satellite [GO:0034451]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; keratin filament [GO:0045095]; microtubule organizing center [GO:0005815]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; perinuclear region of cytoplasm [GO:0048471] cadherin binding involved in cell-cell adhesion [GO:0098641]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; structural molecule activity [GO:0005198] 0 114.09 AQIFANTVDNAR 10.8943 10.1455 9.05151 0 0 0 11.6119 11.7774 11.4404 11.7888 9.67248 0 0 0 0 0 10.6789 10.8183 13.3819 13.0762 13.0678 13.1191 13.0196 13.1428 14.2485 14.1977 13.6151 P05787 K2C8_HUMAN "Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8) (Type-II keratin Kb8)" KRT8 CYK8 Homo sapiens (Human) cell differentiation involved in embryonic placenta development [GO:0060706]; extrinsic apoptotic signaling pathway [GO:0097191]; hepatocyte apoptotic process [GO:0097284]; response to hydrostatic pressure [GO:0051599]; response to other organism [GO:0051707]; sarcomere organization [GO:0045214]; tumor necrosis factor-mediated signaling pathway [GO:0033209] apicolateral plasma membrane [GO:0016327]; cell-cell junction [GO:0005911]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dystrophin-associated glycoprotein complex [GO:0016010]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; intermediate filament cytoskeleton [GO:0045111]; keratin filament [GO:0045095]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; sarcolemma [GO:0042383]; Z disc [GO:0030018] protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110] 0 291.04 AEAESMYQIK 15.8245 13.2091 15.732 0 0 0 13.2784 16.4343 13.5935 10.9105 12.0957 9.74593 0 0 0 10.5986 10.8132 9.61119 15.2124 14.8671 14.9523 14.9627 15.0108 14.7653 16.6885 16.5102 16.2466 P05937 CALB1_HUMAN "Calbindin (Calbindin D28) (D-28K) (Vitamin D-dependent calcium-binding protein, avian-type)" CALB1 CAB27 Homo sapiens (Human) cellular response to organic substance [GO:0071310]; cochlea development [GO:0090102]; locomotory behavior [GO:0007626]; long-term memory [GO:0007616]; metanephric collecting duct development [GO:0072205]; metanephric connecting tubule development [GO:0072286]; metanephric distal convoluted tubule development [GO:0072221]; metanephric part of ureteric bud development [GO:0035502]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; retina layer formation [GO:0010842]; short-term memory [GO:0007614] axon [GO:0030424]; calyx of Held [GO:0044305]; cuticular plate [GO:0032437]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; stereocilium [GO:0032420]; synapse [GO:0045202]; terminal bouton [GO:0043195] calcium ion binding [GO:0005509]; calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration [GO:0099567]; calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration [GO:0099534]; vitamin D binding [GO:0005499]; zinc ion binding [GO:0008270] 0.9695 -4.0506 AGLELSPEMK 0 0 8.67062 0 0 0 0 0 0 0 0 0 10.4877 0 0 0 0 0 0 0 0 9.32513 9.89833 10.9987 11.3136 0 0 P05997 CO5A2_HUMAN Collagen alpha-2(V) chain COL5A2 Homo sapiens (Human) cellular response to amino acid stimulus [GO:0071230]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye morphogenesis [GO:0048592]; negative regulation of endodermal cell differentiation [GO:1903225]; ossification [GO:0001503]; skeletal system development [GO:0001501]; skin development [GO:0043588] collagen type V trimer [GO:0005588]; collagen type XI trimer [GO:0005592]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020]; metal ion binding [GO:0046872]; SMAD binding [GO:0046332] 0.96684 -2.8295 GRLGPQGAPGQR 0 0 0 0 0 0 0 0 0 9.52757 0 0 0 0 12.2772 10.4636 0 0 0 0 0 0 0 9.44313 0 0 0 P06028 GLPB_HUMAN Glycophorin-B (PAS-3) (SS-active sialoglycoprotein) (Sialoglycoprotein delta) (CD antigen CD235b) GYPB GPB Homo sapiens (Human) plasma membrane [GO:0005886] 0.87147 0.030334 SYISSQTNGETGQLVHR 0 0 0 0 0 0 0 0 0 0 10.6168 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P06127 CD5_HUMAN T-cell surface glycoprotein CD5 (Lymphocyte antigen T1/Leu-1) (CD antigen CD5) CD5 LEU1 Homo sapiens (Human) apoptotic signaling pathway [GO:0097190]; cell recognition [GO:0008037]; T cell costimulation [GO:0031295] external side of plasma membrane [GO:0009897]; plasma membrane [GO:0005886] scavenger receptor activity [GO:0005044]; signaling receptor activity [GO:0038023] 0.95822 -1.8683 LTRSNSK 9.01061 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P06213 INSR_HUMAN Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta] INSR Homo sapiens (Human) activation of protein kinase activity [GO:0032147]; activation of protein kinase B activity [GO:0032148]; adrenal gland development [GO:0030325]; amyloid-beta clearance [GO:0097242]; carbohydrate metabolic process [GO:0005975]; cellular response to growth factor stimulus [GO:0071363]; cellular response to insulin stimulus [GO:0032869]; dendritic spine maintenance [GO:0097062]; epidermis development [GO:0008544]; exocrine pancreas development [GO:0031017]; G protein-coupled receptor signaling pathway [GO:0007186]; glucose homeostasis [GO:0042593]; heart morphogenesis [GO:0003007]; insulin receptor signaling pathway [GO:0008286]; learning [GO:0007612]; male gonad development [GO:0008584]; male sex determination [GO:0030238]; memory [GO:0007613]; neuron projection maintenance [GO:1990535]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of developmental growth [GO:0048639]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of glycolytic process [GO:0045821]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of meiotic cell cycle [GO:0051446]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein-containing complex disassembly [GO:0043243]; positive regulation of receptor internalization [GO:0002092]; positive regulation of respiratory burst [GO:0060267]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of DNA-templated transcription [GO:0006355]; regulation of embryonic development [GO:0045995]; regulation of female gonad development [GO:2000194]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; transport across blood-brain barrier [GO:0150104]; viral entry into host cell [GO:0046718] axon [GO:0030424]; caveola [GO:0005901]; dendrite membrane [GO:0032590]; endosome membrane [GO:0010008]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; insulin receptor complex [GO:0005899]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; cargo receptor activity [GO:0038024]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; insulin binding [GO:0043559]; insulin receptor activity [GO:0005009]; insulin receptor substrate binding [GO:0043560]; insulin-like growth factor I binding [GO:0031994]; insulin-like growth factor II binding [GO:0031995]; insulin-like growth factor receptor binding [GO:0005159]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein tyrosine kinase activator activity [GO:0030296]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; PTB domain binding [GO:0051425]; structural molecule activity [GO:0005198] 0.88258 -0.07087 LCLSEIHKMEEVSGTKGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1211 0 0 0 0 0 0 P06239 LCK_HUMAN Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK) LCK Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; B cell receptor signaling pathway [GO:0050853]; Fc-gamma receptor signaling pathway [GO:0038094]; hemopoiesis [GO:0030097]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular zinc ion homeostasis [GO:0006882]; leukocyte migration [GO:0050900]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte cell-cell adhesion [GO:1903039]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell receptor signaling pathway [GO:0050862]; protein phosphorylation [GO:0006468]; regulation of lymphocyte activation [GO:0051249]; release of sequestered calcium ion into cytosol [GO:0051209]; response to xenobiotic stimulus [GO:0009410]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; immunological synapse [GO:0001772]; membrane raft [GO:0045121]; pericentriolar material [GO:0000242]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; ATPase binding [GO:0051117]; CD4 receptor binding [GO:0042609]; CD8 receptor binding [GO:0042610]; identical protein binding [GO:0042802]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatidylinositol 3-kinase binding [GO:0043548]; phospholipase activator activity [GO:0016004]; phospholipase binding [GO:0043274]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; signaling receptor binding [GO:0005102]; T cell receptor binding [GO:0042608] 0.92204 -1.1249 GEQLRILEQSGEWWK 0 0 0 10.5826 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.09265 0 P06241 FYN_HUMAN Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn) FYN Homo sapiens (Human) activated T cell proliferation [GO:0050798]; adaptive immune response [GO:0002250]; axon guidance [GO:0007411]; calcium ion transport [GO:0006816]; cell differentiation [GO:0030154]; cellular response to amyloid-beta [GO:1904646]; cellular response to glycine [GO:1905430]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to L-glutamate [GO:1905232]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to transforming growth factor beta stimulus [GO:0071560]; dendrite morphogenesis [GO:0048813]; dendritic spine maintenance [GO:0097062]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ephrin receptor signaling pathway [GO:0048013]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; feeding behavior [GO:0007631]; forebrain development [GO:0030900]; heart process [GO:0003015]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; learning [GO:0007612]; leukocyte migration [GO:0050900]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide biosynthetic process [GO:0010730]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein ubiquitination [GO:0031397]; neuron migration [GO:0001764]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein localization to membrane [GO:1905477]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of cell shape [GO:0008360]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; response to amyloid-beta [GO:1904645]; response to ethanol [GO:0045471]; response to singlet oxygen [GO:0000304]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] actin filament [GO:0005884]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome [GO:0005768]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glial cell projection [GO:0097386]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear endoplasmic reticulum [GO:0097038]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; Schaffer collateral - CA1 synapse [GO:0098685] alpha-tubulin binding [GO:0043014]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; growth factor receptor binding [GO:0070851]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phospholipase activator activity [GO:0016004]; phospholipase binding [GO:0043274]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321]; transmembrane transporter binding [GO:0044325]; type 5 metabotropic glutamate receptor binding [GO:0031802] 0.89896 -0.61591 EVLEQVERGYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9015 P06276 CHLE_HUMAN Cholinesterase (EC 3.1.1.8) (Acylcholine acylhydrolase) (Butyrylcholine esterase) (Choline esterase II) (Pseudocholinesterase) BCHE CHE1 Homo sapiens (Human) acetylcholine catabolic process [GO:0006581]; choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; peptide hormone processing [GO:0016486]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; xenobiotic metabolic process [GO:0006805] blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; nuclear envelope lumen [GO:0005641]; plasma membrane [GO:0005886] "acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]" 0.89773 -0.62638 ESILFHYTDWVDDQRPENYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.97771 0 0 0 0 0 P06396 GELS_HUMAN Gelsolin (AGEL) (Actin-depolymerizing factor) (ADF) (Brevin) GSN Homo sapiens (Human) "actin filament capping [GO:0051693]; actin filament depolymerization [GO:0030042]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; actin filament severing [GO:0051014]; actin polymerization or depolymerization [GO:0008154]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cardiac muscle cell contraction [GO:0086003]; cell projection assembly [GO:0030031]; cellular response to type II interferon [GO:0071346]; central nervous system development [GO:0007417]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; relaxation of cardiac muscle [GO:0055119]; renal protein absorption [GO:0097017]; response to muscle stretch [GO:0035994]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]" actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774] "actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; phosphatidylinositol 3-kinase catalytic subunit binding [GO:0036313]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]" 0 18.317 AGALNSNDAFVLK 0 0 0 0 0 0 0 0 0 0 8.33842 8.3557 10.4478 10.2649 10.9377 0 8.48788 0 9.91852 0 11.1581 8.63296 0 0 0 0 10.8554 P06400 RB_HUMAN Retinoblastoma-associated protein (p105-Rb) (p110-RB1) (pRb) (Rb) (pp110) RB1 Homo sapiens (Human) "aortic valve morphogenesis [GO:0003180]; cell differentiation [GO:0030154]; cell division [GO:0051301]; cell morphogenesis involved in neuron differentiation [GO:0048667]; cellular response to insulin stimulus [GO:0032869]; cellular response to xenobiotic stimulus [GO:0071466]; chondrocyte differentiation [GO:0002062]; chromatin remodeling [GO:0006338]; chromosome organization [GO:0051276]; digestive tract development [GO:0048565]; enucleate erythrocyte differentiation [GO:0043353]; epithelial cell proliferation [GO:0050673]; glial cell apoptotic process [GO:0034349]; glial cell proliferation [GO:0014009]; hepatocyte apoptotic process [GO:0097284]; heterochromatin formation [GO:0031507]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; myoblast differentiation [GO:0045445]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of hepatocyte apoptotic process [GO:1903944]; negative regulation of inflammatory response [GO:0050728]; negative regulation of myofibroblast differentiation [GO:1904761]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071930]; neuron apoptotic process [GO:0051402]; neuron maturation [GO:0042551]; neuron projection development [GO:0031175]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of extracellular matrix organization [GO:1903055]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein localization to chromosome, centromeric region [GO:0071459]; Ras protein signal transduction [GO:0007265]; regulation of cell cycle [GO:0051726]; regulation of centromere complex assembly [GO:0090230]; regulation of DNA-templated transcription [GO:0006355]; regulation of lipid kinase activity [GO:0043550]; regulation of mitotic cell cycle [GO:0007346]; sister chromatid biorientation [GO:0031134]; skeletal muscle cell differentiation [GO:0035914]; smoothened signaling pathway [GO:0007224]; spermatogenesis [GO:0007283]; striated muscle cell differentiation [GO:0051146]; tissue homeostasis [GO:0001894]; transcription by RNA polymerase II [GO:0006366]" chromatin [GO:0000785]; chromatin lock complex [GO:0061793]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; Rb-E2F complex [GO:0035189]; spindle [GO:0005819]; SWI/SNF complex [GO:0016514] disordered domain specific binding [GO:0097718]; DNA-binding transcription factor binding [GO:0140297]; identical protein binding [GO:0042802]; importin-alpha family protein binding [GO:0061676]; kinase binding [GO:0019900]; molecular adaptor activity [GO:0060090]; phosphoprotein binding [GO:0051219]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625] 0.92459 -1.0072 FQKINQMVCNSDR 0 0 0 0 0 0 0 0 0 0 0 0 10.1504 0 0 0 0 0 0 0 0 0 0 9.42947 9.92569 0 0 P06401 PRGR_HUMAN Progesterone receptor (PR) (Nuclear receptor subfamily 3 group C member 3) PGR NR3C3 Homo sapiens (Human) cell-cell signaling [GO:0007267]; glandular epithelial cell maturation [GO:0002071]; lung alveolus development [GO:0048286]; negative regulation of gene expression [GO:0010629]; ovulation from ovarian follicle [GO:0001542]; paracrine signaling [GO:0038001]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; progesterone receptor signaling pathway [GO:0050847]; regulation of epithelial cell proliferation [GO:0050678]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; tertiary branching involved in mammary gland duct morphogenesis [GO:0060748] chromatin [GO:0000785]; cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] "ATPase binding [GO:0051117]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; estrogen response element binding [GO:0034056]; G protein-coupled receptor activity [GO:0004930]; identical protein binding [GO:0042802]; nuclear receptor activity [GO:0004879]; nuclear steroid receptor activity [GO:0003707]; nucleic acid binding [GO:0003676]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; signaling receptor binding [GO:0005102]; steroid binding [GO:0005496]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]" 0.84188 0.17827 VLSPLMSR 0 0 0 0 0 0 0 0 0 0 9.70098 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P06454 PTMA_HUMAN "Prothymosin alpha [Cleaved into: Prothymosin alpha, N-terminally processed; Thymosin alpha-1]" PTMA TMSA Homo sapiens (Human) DNA-templated transcription [GO:0006351]; negative regulation of apoptotic process [GO:0043066]; positive regulation of transcription by RNA polymerase II [GO:0045944] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA-binding transcription factor binding [GO:0140297]; histone binding [GO:0042393]; ion binding [GO:0043167] 0 53.434 AAEDDEDDDVDTKK 10.1882 9.88653 10.1713 8.95239 8.62881 8.94875 12.1485 12.0168 11.9968 11.0413 11.0966 10.9857 9.98797 9.83689 9.90494 9.84072 10.0272 10.1089 9.73461 9.61005 9.6079 10.8908 10.9683 10.8969 9.30211 9.34041 9.30504 P06493 CDK1_HUMAN Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase) CDK1 CDC2 CDC28A CDKN1 P34CDC2 Homo sapiens (Human) animal organ regeneration [GO:0031100]; apoptotic process [GO:0006915]; cell division [GO:0051301]; cell migration [GO:0016477]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic cyclic compound [GO:0071407]; centrosome cycle [GO:0007098]; chromosome condensation [GO:0030261]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; epithelial cell differentiation [GO:0030855]; ERK1 and ERK2 cascade [GO:0070371]; fibroblast proliferation [GO:0048144]; G2/M transition of mitotic cell cycle [GO:0000086]; Golgi disassembly [GO:0090166]; microtubule cytoskeleton organization [GO:0000226]; microtubule cytoskeleton organization involved in mitosis [GO:1902850]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of DNA replication [GO:0045740]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of mitochondrial ATP synthesis coupled electron transport [GO:1905448]; positive regulation of mitotic sister chromatid segregation [GO:0062033]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein localization to nucleus [GO:1900182]; pronuclear fusion [GO:0007344]; protein deubiquitination [GO:0016579]; protein localization to kinetochore [GO:0034501]; protein phosphorylation [GO:0006468]; protein-containing complex assembly [GO:0065003]; regulation of circadian rhythm [GO:0042752]; regulation of embryonic development [GO:0045995]; regulation of Schwann cell differentiation [GO:0014038]; response to activity [GO:0014823]; response to amine [GO:0014075]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to toxic substance [GO:0009636]; response to xenobiotic stimulus [GO:0009410]; rhythmic process [GO:0048511]; ventricular cardiac muscle cell development [GO:0055015] "centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; cyclin B1-CDK1 complex [GO:0097125]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; mitotic spindle [GO:0072686]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle microtubule [GO:0005876]" acetyltransferase activator activity [GO:0010698]; ATP binding [GO:0005524]; ATPase activator activity [GO:0001671]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; enzyme activator activity [GO:0008047]; histone kinase activity [GO:0035173]; Hsp70 protein binding [GO:0030544]; kinase activity [GO:0016301]; kinase inhibitor activity [GO:0019210]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; virus receptor activity [GO:0001618] 0.53581 0.58215 MLIYDPAKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.374 0 0 0 0 0 0 0 0 P06576 ATPB_HUMAN "ATP synthase subunit beta, mitochondrial (EC 7.1.2.2) (ATP synthase F1 subunit beta)" ATP5F1B ATP5B ATPMB ATPSB Homo sapiens (Human) angiogenesis [GO:0001525]; ATP biosynthetic process [GO:0006754]; cellular response to interleukin-7 [GO:0098761]; generation of precursor metabolites and energy [GO:0006091]; lipid metabolic process [GO:0006629]; negative regulation of cell adhesion involved in substrate-bound cell migration [GO:0006933]; osteoblast differentiation [GO:0001649]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; proton motive force-driven ATP synthesis [GO:0015986]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]; proton transmembrane transport [GO:1902600]; regulation of intracellular pH [GO:0051453] "cell surface [GO:0009986]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrial nucleoid [GO:0042645]; mitochondrial proton-transporting ATP synthase complex [GO:0005753]; mitochondrial proton-transporting ATP synthase, catalytic core [GO:0005754]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex [GO:0045259]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]" "angiostatin binding [GO:0043532]; ATP binding [GO:0005524]; MHC class I protein binding [GO:0042288]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]" 0 113.3 AIAELGIYPAVDPLDSTSR 11.6872 11.122 11.5043 0 0 0 12.8175 12.6219 12.862 10.591 9.60933 11.8244 11.4288 11.4743 11.3458 11.8438 11.6858 11.9003 13.5519 12.8634 12.6112 12.9899 12.8699 12.9762 14.7034 14.7077 14.3697 P06681 CO2_HUMAN Complement C2 (EC 3.4.21.43) (C3/C5 convertase) [Cleaved into: Complement C2b fragment; Complement C2a fragment] C2 Homo sapiens (Human) "complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of immune response [GO:0050778]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508]; response to lipopolysaccharide [GO:0032496]; response to thyroid hormone [GO:0097066]" classical-complement-pathway C3/C5 convertase complex [GO:0005601]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252] 0.80789 0.23452 VNVGDPK 0 0 0 0 0 0 0 0 0 0 9.45951 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P06702 S10A9_HUMAN Protein S100-A9 (Calgranulin-B) (Calprotectin L1H subunit) (Leukocyte L1 complex heavy chain) (Migration inhibitory factor-related protein 14) (MRP-14) (p14) (S100 calcium-binding protein A9) S100A9 CAGB CFAG MRP14 Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; cell-cell signaling [GO:0007267]; chronic inflammatory response [GO:0002544]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; endothelial cell migration [GO:0043542]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; modulation of process of another organism [GO:0035821]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; peptidyl-cysteine S-nitrosylation [GO:0018119]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of cytoskeleton organization [GO:0051493]; regulation of integrin biosynthetic process [GO:0045113]; response to lipopolysaccharide [GO:0032496]; sequestering of zinc ion [GO:0032119] collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774] antioxidant activity [GO:0016209]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270] 0 5.8888 DLQNFLK 0 0 0 0 0 0 0 0 0 9.98185 10.0623 10.7289 10.3619 9.56989 9.47269 11.5457 10.5006 10.2554 0 0 0 0 0 0 0 0 0 P06703 S10A6_HUMAN Protein S100-A6 (Calcyclin) (Growth factor-inducible protein 2A9) (MLN 4) (Prolactin receptor-associated protein) (PRA) (S100 calcium-binding protein A6) S100A6 CACY Homo sapiens (Human) axonogenesis [GO:0007409]; positive regulation of fibroblast proliferation [GO:0048146]; signal transduction [GO:0007165] collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle [GO:0001726] calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; monoatomic ion transmembrane transporter activity [GO:0015075]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; tropomyosin binding [GO:0005523]; zinc ion binding [GO:0008270] 0.0078125 2.0471 LMEDLDR 9.08725 0 0 0 0 0 0 0 0 0 11.9392 0 0 9.59954 9.41867 0 10.8577 0 9.48844 0 0 0 0 0 0 0 0 P06730 IF4E_HUMAN Eukaryotic translation initiation factor 4E (eIF-4E) (eIF4E) (eIF-4F 25 kDa subunit) (mRNA cap-binding protein) EIF4E EIF4EL1 EIF4F Homo sapiens (Human) "behavioral fear response [GO:0001662]; cellular response to dexamethasone stimulus [GO:0071549]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of translation [GO:0017148]; neuron differentiation [GO:0030182]; positive regulation of mitotic cell cycle [GO:0045931]; regulation of translation [GO:0006417]; regulation of translation at postsynapse, modulating synaptic transmission [GO:0099578]; stem cell population maintenance [GO:0019827]; translational initiation [GO:0006413]" chromatoid body [GO:0033391]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; eukaryotic translation initiation factor 4F complex [GO:0016281]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; mRNA cap binding complex [GO:0005845]; nucleus [GO:0005634]; P-body [GO:0000932]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; RISC complex [GO:0016442] DNA-binding transcription factor binding [GO:0140297]; enzyme binding [GO:0019899]; eukaryotic initiation factor 4G binding [GO:0031370]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]; translation initiation factor activity [GO:0003743] 0.85595 0.10311 MATVEPETTPTPNPPTTEEEK 0 0 0 0 0 0 0 0 0 0 9.59587 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P06732 KCRM_HUMAN Creatine kinase M-type (EC 2.7.3.2) (Creatine kinase M chain) (Creatine phosphokinase M-type) (CPK-M) (M-CK) CKM CKMM Homo sapiens (Human) phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] cytosol [GO:0005829]; extracellular space [GO:0005615] ATP binding [GO:0005524]; creatine kinase activity [GO:0004111] 0.95899 -1.8652 ELFDPIISDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.88503 9.62143 0 0 0 P06733 ENOA_HUMAN Alpha-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (C-myc promoter-binding protein) (Enolase 1) (MBP-1) (MPB-1) (Non-neural enolase) (NNE) (Phosphopyruvate hydratase) (Plasminogen-binding protein) ENO1 ENO1L1 MBPB1 MPB1 Homo sapiens (Human) canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; negative regulation of cell growth [GO:0030308]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of muscle contraction [GO:0045933]; positive regulation of plasminogen activation [GO:0010756]; response to virus [GO:0009615] cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; M band [GO:0031430]; membrane [GO:0016020]; nuclear outer membrane [GO:0005640]; nucleus [GO:0005634]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886] "cadherin binding [GO:0045296]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; GTPase binding [GO:0051020]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; transcription corepressor activity [GO:0003714]; transcription corepressor binding [GO:0001222]" 0 227.29 AAVPSGASTGIYEALELR 14.5415 14.4097 14.4545 12.3969 12.2437 12.375 15.1313 15.1346 15.3332 14.1837 13.8859 14.1761 14.3373 14.3777 14.6456 14.577 14.3706 13.9185 13.6658 13.4713 13.656 12.9164 12.3905 12.7741 14.531 14.247 14.5533 P06737 PYGL_HUMAN "Glycogen phosphorylase, liver form (EC 2.4.1.1)" PYGL Homo sapiens (Human) 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; glucose homeostasis [GO:0042593]; glycogen catabolic process [GO:0005980]; glycogen metabolic process [GO:0005977]; necroptotic process [GO:0070266]; response to bacterium [GO:0009617] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774] AMP binding [GO:0016208]; ATP binding [GO:0005524]; bile acid binding [GO:0032052]; glucose binding [GO:0005536]; glycogen phosphorylase activity [GO:0008184]; identical protein binding [GO:0042802]; linear malto-oligosaccharide phosphorylase activity [GO:0102250]; purine nucleobase binding [GO:0002060]; pyridoxal phosphate binding [GO:0030170]; SHG alpha-glucan phosphorylase activity [GO:0102499]; vitamin binding [GO:0019842] 0.95974 -1.7498 LKFSQFLETEYK 0 9.31897 9.94396 9.89304 9.0642 8.66391 9.35935 9.69625 9.77189 0 0 0 8.96967 9.10659 0 9.53914 9.55107 9.58922 0 0 0 0 9.13407 0 0 0 0 P06744 G6PI_HUMAN Glucose-6-phosphate isomerase (GPI) (EC 5.3.1.9) (Autocrine motility factor) (AMF) (Neuroleukin) (NLK) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI) (Sperm antigen 36) (SA-36) GPI Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; hemostasis [GO:0007599]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin production [GO:0002639]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574] ciliary membrane [GO:0060170]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; neuron projection [GO:0043005]; secretory granule lumen [GO:0034774] carbohydrate derivative binding [GO:0097367]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625] 0 42.862 HFVALSTNTTK 0 0 0 0 0 0 0 0 0 10.752 10.6822 9.55903 10.7618 11.6668 10.5926 10.1907 12.0019 8.96532 11.6599 11.2654 11.0514 11.6658 11.1615 12.7614 11.7321 12.9523 12.7096 P06748 NPM_HUMAN Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin) NPM1 NPM Homo sapiens (Human) cellular response to UV [GO:0034644]; cellular senescence [GO:0090398]; centrosome cycle [GO:0007098]; chromatin remodeling [GO:0006338]; DNA repair [GO:0006281]; intracellular protein transport [GO:0006886]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of centrosome duplication [GO:0010826]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; nucleocytoplasmic transport [GO:0006913]; nucleosome assembly [GO:0006334]; positive regulation of cell cycle G2/M phase transition [GO:1902751]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; protein localization [GO:0008104]; regulation of centriole replication [GO:0046599]; regulation of centrosome duplication [GO:0010824]; regulation of eIF2 alpha phosphorylation by dsRNA [GO:0060735]; regulation of endodeoxyribonuclease activity [GO:0032071]; regulation of endoribonuclease activity [GO:0060699]; regulation of mRNA stability involved in cellular response to UV [GO:1902629]; ribosomal large subunit biogenesis [GO:0042273]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit biogenesis [GO:0042274]; ribosomal small subunit export from nucleus [GO:0000056]; ribosome assembly [GO:0042255]; rRNA export from nucleus [GO:0006407]; signal transduction [GO:0007165] centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; granular component [GO:0001652]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; spindle pole centrosome [GO:0031616] chromatin binding [GO:0003682]; core promoter sequence-specific DNA binding [GO:0001046]; DNA-binding transcription factor binding [GO:0140297]; histone binding [GO:0042393]; molecular condensate scaffold activity [GO:0140693]; NF-kappaB binding [GO:0051059]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein kinase inhibitor activity [GO:0004860]; ribosomal large subunit binding [GO:0043023]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; rRNA binding [GO:0019843]; Tat protein binding [GO:0030957]; transcription coactivator activity [GO:0003713]; unfolded protein binding [GO:0051082] 0 58.074 GPSSVEDIK 10.3351 10.2267 10.4195 8.61534 8.77241 8.77396 11.5831 11.3861 11.6689 10.4891 0 0 10.7331 11.0113 10.2567 11.3356 10.7957 10.4302 11.5624 11.0545 10.7836 11.2019 11.9527 10.708 12.8359 12.9297 11.8607 P06753 TPM3_HUMAN Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5) TPM3 Homo sapiens (Human) actin filament organization [GO:0007015]; muscle contraction [GO:0006936] actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; muscle thin filament tropomyosin [GO:0005862]; stress fiber [GO:0001725] actin filament binding [GO:0051015] 0 8.5149 AADAEAEVASLNR 0 11.8878 11.5174 0 0 8.65589 11.4404 11.6517 11.1174 0 10.5271 11.1773 10.0349 9.89668 9.97398 10.9264 10.7154 0 0 0 0 0 0 0 0 0 0 P06756 ITAV_HUMAN Integrin alpha-V (Vitronectin receptor) (Vitronectin receptor subunit alpha) (CD antigen CD51) [Cleaved into: Integrin alpha-V heavy chain; Integrin alpha-V light chain] ITGAV MSK8 VNRA VTNR Homo sapiens (Human) angiogenesis [GO:0001525]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; calcium ion transmembrane transport [GO:0070588]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; endodermal cell differentiation [GO:0035987]; entry into host cell by a symbiont-containing vacuole [GO:0085017]; ERK1 and ERK2 cascade [GO:0070371]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; negative chemotaxis [GO:0050919]; negative regulation of entry of bacterium into host cell [GO:2000536]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; regulation of phagocytosis [GO:0050764]; regulation of transforming growth factor beta activation [GO:1901388]; substrate adhesion-dependent cell spreading [GO:0034446]; transforming growth factor beta production [GO:0071604]; vasculogenesis [GO:0001570]; viral entry into host cell [GO:0046718] alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; integrin alphav-beta3 complex [GO:0034683]; integrin alphav-beta5 complex [GO:0034684]; integrin alphav-beta6 complex [GO:0034685]; integrin alphav-beta8 complex [GO:0034686]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; membrane [GO:0016020]; microvillus membrane [GO:0031528]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; specific granule membrane [GO:0035579] coreceptor activity [GO:0015026]; extracellular matrix binding [GO:0050840]; extracellular matrix protein binding [GO:1990430]; fibronectin binding [GO:0001968]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; opsonin binding [GO:0001846]; protease binding [GO:0002020]; protein kinase C binding [GO:0005080]; transforming growth factor beta binding [GO:0050431]; virus receptor activity [GO:0001618]; voltage-gated calcium channel activity [GO:0005245] 0.8982 -0.66699 AFPPRRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.086 0 0 0 0 0 0 0 0 0 0 P06858 LIPL_HUMAN Lipoprotein lipase (LPL) (EC 3.1.1.34) (Phospholipase A1) (EC 3.1.1.32) LPL LIPD Homo sapiens (Human) cellular response to fatty acid [GO:0071398]; cellular response to nutrient [GO:0031670]; cholesterol homeostasis [GO:0042632]; chylomicron remodeling [GO:0034371]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]; lipid catabolic process [GO:0016042]; low-density lipoprotein particle mediated signaling [GO:0055096]; negative regulation of cellular response to insulin stimulus [GO:1900077]; phospholipid metabolic process [GO:0006644]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine production [GO:0032722]; positive regulation of cholesterol storage [GO:0010886]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of lipid storage [GO:0010884]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of sequestering of triglyceride [GO:0010890]; positive regulation of tumor necrosis factor production [GO:0032760]; response to bacterium [GO:0009617]; response to cold [GO:0009409]; response to glucose [GO:0009749]; response to xenobiotic stimulus [GO:0009410]; triglyceride biosynthetic process [GO:0019432]; triglyceride catabolic process [GO:0019433]; triglyceride homeostasis [GO:0070328]; triglyceride metabolic process [GO:0006641]; very-low-density lipoprotein particle remodeling [GO:0034372] catalytic complex [GO:1902494]; cell surface [GO:0009986]; chylomicron [GO:0042627]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; very-low-density lipoprotein particle [GO:0034361] 1-acyl-2-lysophosphatidylserine acylhydrolase activity [GO:0052740]; apolipoprotein binding [GO:0034185]; calcium ion binding [GO:0005509]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; lipase activity [GO:0016298]; lipoprotein lipase activity [GO:0004465]; lipoprotein particle binding [GO:0071813]; phosphatidylserine 1-acylhydrolase activity [GO:0052739]; phospholipase A1 activity [GO:0008970]; phospholipase activity [GO:0004620]; protein homodimerization activity [GO:0042803]; protein-membrane adaptor activity [GO:0043495]; signaling receptor binding [GO:0005102]; triglyceride binding [GO:0017129]; triglyceride lipase activity [GO:0004806] 0.82537 0.21194 CSSKEAFEKGLCLSCR 0 0 0 0 0 0 9.9499 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P06865 HEXA_HUMAN Beta-hexosaminidase subunit alpha (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit alpha) (Hexosaminidase subunit A) (N-acetyl-beta-glucosaminidase subunit alpha) HEXA Homo sapiens (Human) adult walking behavior [GO:0007628]; cell morphogenesis involved in neuron differentiation [GO:0048667]; dermatan sulfate catabolic process [GO:0030209]; ganglioside catabolic process [GO:0006689]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan metabolic process [GO:0030203]; hyaluronan catabolic process [GO:0030214]; lipid storage [GO:0019915]; lysosome organization [GO:0007040]; maintenance of location in cell [GO:0051651]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; sensory perception of sound [GO:0007605]; sexual reproduction [GO:0019953]; skeletal system development [GO:0001501]; SMAD protein signal transduction [GO:0060395] azurophil granule [GO:0042582]; beta-N-acetylhexosaminidase complex [GO:1905379]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020] acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982] 0.91597 -0.77026 EVIEYARLRGIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.63708 0 0 0 0 0 0 0 0 P07093 GDN_HUMAN Glia-derived nexin (GDN) (Peptidase inhibitor 7) (PI-7) (Protease nexin 1) (PN-1) (Protease nexin I) (Serpin E2) SERPINE2 PI7 PN1 Homo sapiens (Human) "cell differentiation [GO:0030154]; cerebellar granular layer morphogenesis [GO:0021683]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; innervation [GO:0060384]; long-term synaptic potentiation [GO:0060291]; mating plug formation [GO:0042628]; negative regulation of blood coagulation [GO:0030195]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of plasminogen activation [GO:0010757]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein processing [GO:0010955]; negative regulation of proteolysis [GO:0045861]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of sodium ion transport [GO:0010766]; platelet activation [GO:0030168]; positive regulation of astrocyte differentiation [GO:0048711]; protein catabolic process [GO:0030163]; regulation of cell migration [GO:0030334]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of timing of cell differentiation [GO:0048505]; secretion by cell [GO:0032940]; secretory granule organization [GO:0033363]; seminal vesicle epithelium development [GO:0061108]" collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; neuromuscular junction [GO:0031594]; platelet alpha granule [GO:0031091] glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor binding [GO:0005102] 0.91494 -0.79606 FQPENTKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0839 0 0 0 0 0 0 0 0 0 0 P07099 HYEP_HUMAN Epoxide hydrolase 1 (EC 3.3.2.9) (Epoxide hydratase) (Microsomal epoxide hydrolase) (mEH) EPHX1 EPHX EPOX Homo sapiens (Human) arachidonic acid metabolic process [GO:0019369]; aromatic compound catabolic process [GO:0019439]; epoxide metabolic process [GO:0097176]; response to organic cyclic compound [GO:0014070]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805] endoplasmic reticulum membrane [GO:0005789] cis-stilbene-oxide hydrolase activity [GO:0033961]; epoxide hydrolase activity [GO:0004301] 0 3.5824 DVELLYPVK 0 0 0 11.3379 9.46683 10.8487 9.8482 10.3057 9.22721 10.1371 9.7435 9.4719 11.073 9.64827 10.0581 9.00596 11.4908 9.69905 11.4627 10.927 11.8178 10.9053 11.3307 9.25406 11.9079 11.4613 10.0275 P07101 TY3H_HUMAN Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH) TH TYH Homo sapiens (Human) "aminergic neurotransmitter loading into synaptic vesicle [GO:0015842]; anatomical structure morphogenesis [GO:0009653]; animal organ morphogenesis [GO:0009887]; cellular response to alkaloid [GO:0071312]; cellular response to glucose stimulus [GO:0071333]; cellular response to growth factor stimulus [GO:0071363]; cellular response to manganese ion [GO:0071287]; cellular response to nicotine [GO:0071316]; cellular response to xenobiotic stimulus [GO:0071466]; cerebral cortex development [GO:0021987]; circadian sleep/wake cycle [GO:0042745]; dopamine biosynthetic process [GO:0042416]; dopamine biosynthetic process from tyrosine [GO:0006585]; eating behavior [GO:0042755]; embryonic camera-type eye morphogenesis [GO:0048596]; epinephrine biosynthetic process [GO:0042418]; eye photoreceptor cell development [GO:0042462]; fatty acid metabolic process [GO:0006631]; glycoside metabolic process [GO:0016137]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; hyaloid vascular plexus regression [GO:1990384]; isoquinoline alkaloid metabolic process [GO:0033076]; learning [GO:0007612]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; multicellular organism aging [GO:0010259]; neurotransmitter biosynthetic process [GO:0042136]; norepinephrine biosynthetic process [GO:0042421]; phthalate metabolic process [GO:0018963]; phytoalexin metabolic process [GO:0052314]; pigmentation [GO:0043473]; regulation of heart contraction [GO:0008016]; response to activity [GO:0014823]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to ether [GO:0045472]; response to herbicide [GO:0009635]; response to hypoxia [GO:0001666]; response to immobilization stress [GO:0035902]; response to isolation stress [GO:0035900]; response to light stimulus [GO:0009416]; response to lipopolysaccharide [GO:0032496]; response to nutrient levels [GO:0031667]; response to peptide hormone [GO:0043434]; response to pyrethroid [GO:0046684]; response to salt stress [GO:0009651]; response to water deprivation [GO:0009414]; response to zinc ion [GO:0010043]; sensory perception of sound [GO:0007605]; social behavior [GO:0035176]; sphingolipid metabolic process [GO:0006665]; synaptic transmission, dopaminergic [GO:0001963]; terpene metabolic process [GO:0042214]; visual perception [GO:0007601]" axon [GO:0030424]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome membrane [GO:0033162]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; smooth endoplasmic reticulum [GO:0005790]; synaptic vesicle [GO:0008021]; terminal bouton [GO:0043195] amino acid binding [GO:0016597]; dopamine binding [GO:0035240]; enzyme binding [GO:0019899]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; identical protein binding [GO:0042802]; oxygen binding [GO:0019825]; protein domain specific binding [GO:0019904]; tetrahydrobiopterin binding [GO:0034617]; tyrosine 3-monooxygenase activity [GO:0004511] 0.92711 -1.2177 QSLIEDARKER 0 11.1736 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P07108 ACBP_HUMAN Acyl-CoA-binding protein (ACBP) (Diazepam-binding inhibitor) (DBI) (Endozepine) (EP) DBI Homo sapiens (Human) fatty acid metabolic process [GO:0006631]; negative regulation of protein lipidation [GO:1903060]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; positive regulation of CoA-transferase activity [GO:1905920]; positive regulation of phospholipid transport [GO:2001140] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; perinuclear endoplasmic reticulum [GO:0097038]; protein-lipid complex [GO:0032994] benzodiazepine receptor binding [GO:0030156]; fatty-acyl-CoA binding [GO:0000062]; identical protein binding [GO:0042802]; long-chain fatty acyl-CoA binding [GO:0036042] 0.93403 -1.2897 AKWDAWNELKGTSK 0 0 0 0 0 0 0 0 0 0 10.0518 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P07195 LDHB_HUMAN L-lactate dehydrogenase B chain (LDH-B) (EC 1.1.1.27) (LDH heart subunit) (LDH-H) (Renal carcinoma antigen NY-REN-46) LDHB Homo sapiens (Human) lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; pyruvate metabolic process [GO:0006090] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; oxidoreductase complex [GO:1990204] identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287] 0 16.871 FIIPQIVK 9.03364 10.6924 10.4606 0 0 0 11.9687 11.5843 11.5378 12.7647 12.9507 12.7185 11.5384 11.4914 11.6602 12.6937 11.644 10.6979 10.6408 10.4471 9.31872 10.5507 9.17542 9.06323 11.3046 11.123 10.7674 P07196 NFL_HUMAN Neurofilament light polypeptide (NF-L) (68 kDa neurofilament protein) (Neurofilament triplet L protein) NEFL NF68 NFL Homo sapiens (Human) anterograde axonal transport [GO:0008089]; axonal transport of mitochondrion [GO:0019896]; axonogenesis [GO:0007409]; cerebral cortex development [GO:0021987]; hippocampus development [GO:0021766]; intermediate filament organization [GO:0045109]; intermediate filament polymerization or depolymerization [GO:0045105]; locomotion [GO:0040011]; microtubule cytoskeleton organization [GO:0000226]; motor neuron apoptotic process [GO:0097049]; negative regulation of motor neuron apoptotic process [GO:2000672]; neurofilament bundle assembly [GO:0033693]; neurofilament cytoskeleton organization [GO:0060052]; neuromuscular process controlling balance [GO:0050885]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of axonogenesis [GO:0050772]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein polymerization [GO:0051258]; regulation of axon diameter [GO:0031133]; regulation of synapse maturation [GO:0090128]; response to acrylamide [GO:1903937]; response to corticosterone [GO:0051412]; response to peptide hormone [GO:0043434]; response to sodium arsenite [GO:1903935]; response to toxic substance [GO:0009636]; retrograde axonal transport [GO:0008090]; spinal cord development [GO:0021510] axon [GO:0030424]; axon cytoplasm [GO:1904115]; cholinergic synapse [GO:0098981]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; intermediate filament [GO:0005882]; neurofilament [GO:0005883]; neuromuscular junction [GO:0031594]; postsynaptic intermediate filament cytoskeleton [GO:0099160]; presynaptic intermediate filament cytoskeleton [GO:0099182]; Schaffer collateral - CA1 synapse [GO:0098685] identical protein binding [GO:0042802]; phospholipase binding [GO:0043274]; protein domain specific binding [GO:0019904]; protein-containing complex binding [GO:0044877]; protein-macromolecule adaptor activity [GO:0030674]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of postsynaptic intermediate filament cytoskeleton [GO:0099184] 0.96741 -3.7922 DIRAQYEK 0 0 0 0 0 10.5828 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.57141 0 9.70662 0 0 P07197 NFM_HUMAN Neurofilament medium polypeptide (NF-M) (160 kDa neurofilament protein) (Neurofilament 3) (Neurofilament triplet M protein) NEFM NEF3 NFM Homo sapiens (Human) neurofilament bundle assembly [GO:0033693] axon [GO:0030424]; cytoplasm [GO:0005737]; intermediate filament [GO:0005882]; intermediate filament cytoskeleton [GO:0045111]; neurofibrillary tangle [GO:0097418]; neurofilament [GO:0005883]; postsynaptic intermediate filament cytoskeleton [GO:0099160] microtubule binding [GO:0008017]; structural constituent of cytoskeleton [GO:0005200] 0.96892 -6.9031 ATLEMVNHEK 0 0 0 0 0 0 10.8366 0 0 12.1716 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1047 P07199 CENPB_HUMAN Major centromere autoantigen B (Centromere protein B) (CENP-B) CENPB Homo sapiens (Human) "chromosome [GO:0005694]; chromosome, centromeric region [GO:0000775]; condensed chromosome, centromeric region [GO:0000779]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]" centromeric DNA binding [GO:0019237]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; satellite DNA binding [GO:0003696]; sequence-specific DNA binding [GO:0043565] 0.92611 -1.1824 TNKLSPYDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5688 0 0 0 0 0 0 0 0 0 0 P07203 GPX1_HUMAN Glutathione peroxidase 1 (GPx-1) (GSHPx-1) (EC 1.11.1.9) (Cellular glutathione peroxidase) GPX1 Homo sapiens (Human) aging [GO:0007568]; angiogenesis involved in wound healing [GO:0060055]; arachidonic acid metabolic process [GO:0019369]; biological process involved in interaction with symbiont [GO:0051702]; blood vessel endothelial cell migration [GO:0043534]; cell redox homeostasis [GO:0045454]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; endothelial cell development [GO:0001885]; epigenetic regulation of gene expression [GO:0040029]; fat cell differentiation [GO:0045444]; fibroblast proliferation [GO:0048144]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide catabolic process [GO:0042744]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; lipoxygenase pathway [GO:0019372]; myoblast differentiation [GO:0045445]; myoblast proliferation [GO:0051450]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; neuron apoptotic process [GO:0051402]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of supramolecular fiber organization [GO:1902905]; protein oxidation [GO:0018158]; regulation of mammary gland epithelial cell proliferation [GO:0033599]; regulation of proteasomal protein catabolic process [GO:0061136]; response to estradiol [GO:0032355]; response to folic acid [GO:0051593]; response to gamma radiation [GO:0010332]; response to hormone [GO:0009725]; response to hydrogen peroxide [GO:0042542]; response to hydroperoxide [GO:0033194]; response to nicotine [GO:0035094]; response to selenium ion [GO:0010269]; response to symbiotic bacterium [GO:0009609]; response to vitamin E [GO:0033197]; response to xenobiotic stimulus [GO:0009410]; sensory perception of sound [GO:0007605]; skeletal muscle fiber development [GO:0048741]; skeletal muscle tissue regeneration [GO:0043403]; temperature homeostasis [GO:0001659]; triglyceride metabolic process [GO:0006641]; UV protection [GO:0009650]; vasodilation [GO:0042311] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634] glutathione peroxidase activity [GO:0004602]; phospholipid-hydroperoxide glutathione peroxidase activity [GO:0047066]; SH3 domain binding [GO:0017124] 0.80939 0.22658 LITWSPVCR 0 0 0 0 0 0 0 0 8.54751 0 0 0 0 0 0 0 0 0 0 0 10.0004 0 0 0 0 0 0 P07205 PGK2_HUMAN "Phosphoglycerate kinase 2 (EC 2.7.2.3) (Phosphoglycerate kinase, testis specific)" PGK2 PGKB Homo sapiens (Human) canonical glycolysis [GO:0061621]; flagellated sperm motility [GO:0030317]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; phosphorylation [GO:0016310] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; sperm fibrous sheath [GO:0035686] ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618] 0.83339 0.19956 ITFPVDFVTGDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.753 0 0 0 0 0 0 0 0 0 0 0 0 P07225 PROS_HUMAN Vitamin K-dependent protein S PROS1 PROS Homo sapiens (Human) blood coagulation [GO:0007596]; fibrinolysis [GO:0042730] blood microparticle [GO:0072562]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093] calcium ion binding [GO:0005509]; endopeptidase inhibitor activity [GO:0004866] 0.81149 0.22472 AHSCPSVWK 0 0 0 9.06824 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P07237 PDIA1_HUMAN Protein disulfide-isomerase (PDI) (EC 5.3.4.1) (Cellular thyroid hormone-binding protein) (Prolyl 4-hydroxylase subunit beta) (p55) P4HB ERBA2L PDI PDIA1 PO4DB Homo sapiens (Human) cellular response to hypoxia [GO:0071456]; cellular response to interleukin-7 [GO:0098761]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; insulin processing [GO:0030070]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; positive regulation of cell adhesion [GO:0045785]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of viral entry into host cell [GO:0046598]; protein folding [GO:0006457]; protein folding in endoplasmic reticulum [GO:0034975]; regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902175]; response to endoplasmic reticulum stress [GO:0034976] cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; procollagen-proline 4-dioxygenase complex [GO:0016222]; protein-containing complex [GO:0032991] actin binding [GO:0003779]; enzyme binding [GO:0019899]; integrin binding [GO:0005178]; procollagen-proline 4-dioxygenase activity [GO:0004656]; protein disulfide isomerase activity [GO:0003756]; protein heterodimerization activity [GO:0046982]; protein-disulfide reductase activity [GO:0015035]; RNA binding [GO:0003723]; thiol oxidase activity [GO:0016972] 0 69.27 AEGSEIR 11.8608 11.6631 11.9045 0 9.21989 0 13.6476 13.7022 13.4338 12.4482 12.4712 11.7708 11.6196 10.5997 10.1834 10.3932 11.1994 10.5833 0 11.498 9.88293 10.3328 10.0133 9.92973 11.8792 11.5931 12.2985 P07305 H10_HUMAN "Histone H1.0 (Histone H1') (Histone H1(0)) [Cleaved into: Histone H1.0, N-terminally processed]" H1-0 H1F0 H1FV Homo sapiens (Human) chromosome condensation [GO:0030261]; heterochromatin formation [GO:0031507]; negative regulation of DNA recombination [GO:0045910]; nucleosome assembly [GO:0006334]; positive regulation of transcription regulatory region DNA binding [GO:2000679] actin cytoskeleton [GO:0015629]; chromatin [GO:0000785]; euchromatin [GO:0000791]; Golgi apparatus [GO:0005794]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; transcription repressor complex [GO:0017053] chromatin DNA binding [GO:0031490]; double-stranded DNA binding [GO:0003690]; minor groove of adenine-thymine-rich DNA binding [GO:0003680]; nucleosomal DNA binding [GO:0031492]; RNA binding [GO:0003723]; structural constituent of chromatin [GO:0030527] 0.0056818 2.2825 GVGASGSFR 0 9.17572 9.1395 0 0 0 8.95102 0 0 9.1354 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P07327 ADH1A_HUMAN Alcohol dehydrogenase 1A (EC 1.1.1.1) (Alcohol dehydrogenase subunit alpha) ADH1A ADH1 Homo sapiens (Human) alcohol metabolic process [GO:0006066]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] "alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; butanol dehydrogenase activity [GO:1990362]; NAD-retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]" 0.94637 -1.3457 ECVPKLVADFMAKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0753 0 0 0 0 0 0 0 0 P07332 FES_HUMAN Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene homolog) (Proto-oncogene c-Fes) (Proto-oncogene c-Fps) (p93c-fes) FES FPS Homo sapiens (Human) cardiac muscle cell proliferation [GO:0060038]; cell adhesion [GO:0007155]; cellular response to vitamin D [GO:0071305]; centrosome cycle [GO:0007098]; chemotaxis [GO:0006935]; microtubule bundle formation [GO:0001578]; myoblast proliferation [GO:0051450]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of myeloid cell differentiation [GO:0045639]; positive regulation of neuron projection development [GO:0010976]; protein autophosphorylation [GO:0046777]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell motility [GO:2000145]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of mast cell degranulation [GO:0043304]; regulation of vesicle-mediated transport [GO:0060627] cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; microtubule cytoskeleton [GO:0015630] ATP binding [GO:0005524]; immunoglobulin receptor binding [GO:0034987]; microtubule binding [GO:0008017]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatidylinositol binding [GO:0035091]; protein tyrosine kinase activity [GO:0004713] 0.95402 -1.5012 SCRETLPPDLK 0 0 9.69799 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P07333 CSF1R_HUMAN Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115) CSF1R FMS Homo sapiens (Human) axon guidance [GO:0007411]; cell population proliferation [GO:0008283]; cell-cell junction maintenance [GO:0045217]; cellular response to cytokine stimulus [GO:0071345]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cytokine-mediated signaling pathway [GO:0019221]; forebrain neuron differentiation [GO:0021879]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; macrophage colony-stimulating factor signaling pathway [GO:0038145]; macrophage differentiation [GO:0030225]; mammary gland duct morphogenesis [GO:0060603]; microglial cell proliferation [GO:0061518]; monocyte differentiation [GO:0030224]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; olfactory bulb development [GO:0021772]; osteoclast differentiation [GO:0030316]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol metabolic process [GO:0046488]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation by host of viral process [GO:0044794]; positive regulation of cell motility [GO:2000147]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of kinase activity [GO:0033674]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of macrophage proliferation [GO:0120041]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein autophosphorylation [GO:0046777]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of bone resorption [GO:0045124]; regulation of cell shape [GO:0008360]; regulation of macrophage migration [GO:1905521]; regulation of MAPK cascade [GO:0043408]; response to ischemia [GO:0002931]; ruffle organization [GO:0031529]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] cell surface [GO:0009986]; CSF1-CSF1R complex [GO:1990682]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] ATP binding [GO:0005524]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; macrophage colony-stimulating factor receptor activity [GO:0005011]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713] 0.96774 -2.7886 DTYRHTFTLSLPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4407 0 0 P07339 CATD_HUMAN Cathepsin D (EC 3.4.23.5) [Cleaved into: Cathepsin D light chain; Cathepsin D heavy chain] CTSD CPSD Homo sapiens (Human) antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; autophagosome assembly [GO:0000045]; insulin catabolic process [GO:1901143]; insulin receptor recycling [GO:0038020]; lipoprotein catabolic process [GO:0042159]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; proteolysis [GO:0006508]; regulation of establishment of protein localization [GO:0070201] collagen-containing extracellular matrix [GO:0062023]; endosome lumen [GO:0031904]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane raft [GO:0045121]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724] aspartic-type endopeptidase activity [GO:0004190]; aspartic-type peptidase activity [GO:0070001]; cysteine-type endopeptidase activity [GO:0004197]; peptidase activity [GO:0008233] 0 28.104 DPDAQPGGELMLGGTDSK 0 0 0 0 0 0 9.36072 0 0 10.5814 9.35542 9.5041 0 9.28536 0 0 10.6413 8.97077 11.8434 11.1035 12.2417 12.3274 11.709 11.8472 13.6781 13.3566 13.3898 P07355 ANXA2_HUMAN Annexin A2 (Annexin II) (Annexin-2) (Calpactin I heavy chain) (Calpactin-1 heavy chain) (Chromobindin-8) (Lipocortin II) (Placental anticoagulant protein IV) (PAP-IV) (Protein I) (p36) ANXA2 ANX2 ANX2L4 CAL1H LPC2D Homo sapiens (Human) angiogenesis [GO:0001525]; collagen fibril organization [GO:0030199]; fibrinolysis [GO:0042730]; membrane raft assembly [GO:0001765]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of receptor internalization [GO:0002091]; osteoclast development [GO:0036035]; positive regulation of exocytosis [GO:0045921]; positive regulation of low-density lipoprotein particle clearance [GO:1905581]; positive regulation of low-density lipoprotein particle receptor binding [GO:1905597]; positive regulation of low-density lipoprotein receptor activity [GO:1905599]; positive regulation of plasma membrane repair [GO:1905686]; positive regulation of plasminogen activation [GO:0010756]; positive regulation of receptor recycling [GO:0001921]; positive regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905602]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vacuole organization [GO:0044090]; positive regulation of vesicle fusion [GO:0031340]; regulation of neurogenesis [GO:0050767]; vesicle budding from membrane [GO:0006900] adherens junction [GO:0005912]; AnxA2-p11 complex [GO:1990665]; azurophil granule lumen [GO:0035578]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; late endosome membrane [GO:0031902]; lipid droplet [GO:0005811]; lysosomal membrane [GO:0005765]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; myelin sheath adaxonal region [GO:0035749]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]; PCSK9-AnxA2 complex [GO:1990667]; plasma membrane [GO:0005886]; plasma membrane protein complex [GO:0098797]; RNA polymerase II transcription regulator complex [GO:0090575]; sarcolemma [GO:0042383]; Schmidt-Lanterman incisure [GO:0043220]; vesicle [GO:0031982] "cadherin binding involved in cell-cell adhesion [GO:0098641]; calcium channel activity [GO:0005262]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipase A2 inhibitor activity [GO:0019834]; protease binding [GO:0002020]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]; serine-type endopeptidase inhibitor activity [GO:0004867]; virion binding [GO:0046790]" 0 131.7 AEDGSVIDYELIDQDAR 12.0789 11.8492 12.752 0 0 0 12.8945 13.0331 12.9958 12.8215 12.0417 12.0799 10.9273 11.3335 11.1968 11.4976 11.3449 10.7361 8.78966 11.4024 11.2431 11.8478 11.7914 10.5561 12.8735 12.6255 10.2724 P07384 CAN1_HUMAN Calpain-1 catalytic subunit (EC 3.4.22.52) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (Calpain-1 large subunit) (Cell proliferation-inducing gene 30 protein) (Micromolar-calpain) (muCANP) CAPN1 CANPL1 PIG30 Homo sapiens (Human) mammary gland involution [GO:0060056]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; receptor catabolic process [GO:0032801]; regulation of catalytic activity [GO:0050790]; regulation of macroautophagy [GO:0016241]; regulation of NMDA receptor activity [GO:2000310]; self proteolysis [GO:0097264] calpain complex [GO:0110158]; cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lysosome [GO:0005764]; membrane [GO:0016020]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; peptidase activity [GO:0008233] 0.96186 -2.0699 GHAYSVTGAKQVNYR 0 0 0 0 0 0 0 0 0 0 8.60463 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P07437 TBB5_HUMAN Tubulin beta chain (Tubulin beta-5 chain) TUBB TUBB5 OK/SW-cl.56 Homo sapiens (Human) cell division [GO:0051301]; cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; natural killer cell mediated cytotoxicity [GO:0042267]; odontoblast differentiation [GO:0071895]; regulation of synapse organization [GO:0050807]; spindle assembly [GO:0051225] azurophil granule lumen [GO:0035578]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; intercellular bridge [GO:0045171]; membrane raft [GO:0045121]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; mitotic spindle [GO:0072686]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] GTP binding [GO:0005525]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; MHC class I protein binding [GO:0042288]; protein domain specific binding [GO:0019904]; protein-containing complex binding [GO:0044877]; structural constituent of cytoskeleton [GO:0005200]; structural molecule activity [GO:0005198]; ubiquitin protein ligase binding [GO:0031625] 0 227.65 AILVDLEPGTMDSVR 13.0862 13.4847 13.2015 10.3125 11.1542 10.0039 14.2229 14.086 14.1185 13.172 12.9296 12.9415 13.8557 13.6948 13.9827 14.4517 14.3489 13.9794 14.177 13.9483 14.4703 13.8051 13.2012 13.9128 15.2733 15.227 15.3977 P07476 INVO_HUMAN Involucrin IVL Homo sapiens (Human) isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; response to UV-B [GO:0010224] centrosome [GO:0005813]; cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604] molecular adaptor activity [GO:0060090] 0.69708 0.38034 HLDQQEK 0 8.48043 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.67545 0 0 P07498 CASK_HUMAN Kappa-casein CSN3 CASK CSN10 CSNK Homo sapiens (Human) lactation [GO:0007595]; protein stabilization [GO:0050821] extracellular region [GO:0005576]; extracellular space [GO:0005615] 0.77383 0.27208 QYLPNSHPPTVVR 0 0 10.2131 0 10.2425 0 0 10.1767 0 11.5629 11.7454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P07602 SAP_HUMAN Prosaposin (Proactivator polypeptide) [Cleaved into: Saposin-A (Protein A); Saposin-B-Val; Saposin-B (Cerebroside sulfate activator) (CSAct) (Dispersin) (Sphingolipid activator protein 1) (SAP-1) (Sulfatide/GM1 activator); Saposin-C (A1 activator) (Co-beta-glucosidase) (Glucosylceramidase activator) (Sphingolipid activator protein 2) (SAP-2); Saposin-D (Component C) (Protein C)] PSAP GLBA SAP1 Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; epithelial cell differentiation involved in prostate gland development [GO:0060742]; ganglioside GM1 transport to membrane [GO:1905572]; lysosomal transport [GO:0007041]; positive regulation of beta-galactosidase activity [GO:1903771]; prostate gland growth [GO:0060736]; regulation of autophagy [GO:0010506]; regulation of lipid metabolic process [GO:0019216]; sphingolipid metabolic process [GO:0006665] azurophil granule membrane [GO:0035577]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; plasma membrane [GO:0005886] enzyme activator activity [GO:0008047]; ganglioside GM1 binding [GO:1905573]; ganglioside GM2 binding [GO:1905574]; ganglioside GM3 binding [GO:1905575]; ganglioside GP1c binding [GO:1905577]; ganglioside GT1b binding [GO:1905576]; identical protein binding [GO:0042802]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110] 0.82321 0.21623 LGPGMADICK 0 0 0 0 0 9.24213 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P07686 HEXB_HUMAN Beta-hexosaminidase subunit beta (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit beta) (Hexosaminidase subunit B) (Cervical cancer proto-oncogene 7 protein) (HCC-7) (N-acetyl-beta-glucosaminidase subunit beta) [Cleaved into: Beta-hexosaminidase subunit beta chain B; Beta-hexosaminidase subunit beta chain A] HEXB HCC7 Homo sapiens (Human) astrocyte cell migration [GO:0043615]; chondroitin sulfate catabolic process [GO:0030207]; dermatan sulfate catabolic process [GO:0030209]; ganglioside catabolic process [GO:0006689]; glycosaminoglycan metabolic process [GO:0030203]; hyaluronan catabolic process [GO:0030214]; intracellular calcium ion homeostasis [GO:0006874]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; maintenance of location in cell [GO:0051651]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neuron cellular homeostasis [GO:0070050]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; single fertilization [GO:0007338]; skeletal system development [GO:0001501] acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; beta-N-acetylhexosaminidase complex [GO:1905379]; cortical granule [GO:0060473]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020] acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; identical protein binding [GO:0042802]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148] 0.40476 0.69927 DSAYPEELSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.42928 0 0 0 9.70867 0 0 P07737 PROF1_HUMAN Profilin-1 (Epididymis tissue protein Li 184a) (Profilin I) PFN1 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; modification of postsynaptic actin cytoskeleton [GO:0098885]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of actin filament bundle assembly [GO:0032232]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of stress fiber assembly [GO:0051497]; neural tube closure [GO:0001843]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of ATP-dependent activity [GO:0032781]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ruffle assembly [GO:1900029]; protein stabilization [GO:0050821]; regulation of actin filament polymerization [GO:0030833]; regulation of transcription by RNA polymerase II [GO:0006357]; synapse maturation [GO:0060074] blood microparticle [GO:0072562]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleus [GO:0005634] "actin binding [GO:0003779]; actin monomer binding [GO:0003785]; adenyl-nucleotide exchange factor activity [GO:0000774]; cadherin binding [GO:0045296]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; RNA binding [GO:0003723]; small GTPase binding [GO:0031267]" 0 41.212 DSLLQDGEFSMDLR 10.8758 10.7685 9.86273 0 0 0 11.6576 11.6264 11.7178 11.7274 9.17884 12.1851 10.5803 10.9407 11.0645 12.5743 12.0793 11.3236 11.8861 10.4609 10.9165 11.6413 11.062 10.4267 12.3987 12.2905 10.057 P07738 PMGE_HUMAN "Bisphosphoglycerate mutase (BPGM) (EC 5.4.2.4) (2,3-bisphosphoglycerate mutase, erythrocyte) (2,3-bisphosphoglycerate synthase) (EC 5.4.2.11) (2,3-diphosphoglycerate mutase) (DPGM) (BPG-dependent PGAM)" BPGM Homo sapiens (Human) carbohydrate derivative catabolic process [GO:1901136]; carbohydrate metabolic process [GO:0005975]; defense response to protozoan [GO:0042832]; erythrocyte development [GO:0048821]; establishment of blood-brain barrier [GO:0060856]; glycolytic process [GO:0006096]; neuroinflammatory response [GO:0150076]; nucleoside phosphate metabolic process [GO:0006753]; oxygen transport [GO:0015671]; respiratory gaseous exchange by respiratory system [GO:0007585] cytosol [GO:0005829]; extracellular exosome [GO:0070062] "2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]" 0.88298 -0.27342 SESLKDVLER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7049 0 0 0 0 0 P07741 APT_HUMAN Adenine phosphoribosyltransferase (APRT) (EC 2.4.2.7) APRT Homo sapiens (Human) adenine salvage [GO:0006168]; AMP salvage [GO:0044209]; cellular response to insulin stimulus [GO:0032869]; GMP salvage [GO:0032263]; grooming behavior [GO:0007625]; IMP salvage [GO:0032264]; lactation [GO:0007595]; purine ribonucleoside salvage [GO:0006166] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; secretory granule lumen [GO:0034774] adenine binding [GO:0002055]; adenine phosphoribosyltransferase activity [GO:0003999]; AMP binding [GO:0016208] 0 12.649 ADSELQLVEQR 0 0 0 0 0 0 8.56784 0 0 0 9.42211 9.42582 9.38357 0 9.12026 0 9.78391 11.1887 9.90037 0 0 9.80967 10.5641 9.63956 0 0 0 P07766 CD3E_HUMAN T-cell surface glycoprotein CD3 epsilon chain (T-cell surface antigen T3/Leu-4 epsilon chain) (CD antigen CD3e) CD3E T3E Homo sapiens (Human) "adaptive immune response [GO:0002250]; alpha-beta T cell activation [GO:0046631]; apoptotic signaling pathway [GO:0097190]; calcium-mediated signaling [GO:0019722]; CD4-positive, alpha-beta T cell proliferation [GO:0035739]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-delta T cell activation [GO:0046629]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of type II interferon production [GO:0032729]; positive thymic T cell selection [GO:0045059]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; signal complex assembly [GO:0007172]; smoothened signaling pathway [GO:0007224]; T cell activation [GO:0042110]; T cell anergy [GO:0002870]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]" alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; gamma-delta T cell receptor complex [GO:0042106]; Golgi apparatus [GO:0005794]; immunological synapse [GO:0001772]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101] identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; SH3 domain binding [GO:0017124]; signaling receptor complex adaptor activity [GO:0030159]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888] 0.64571 0.39623 GAGAGGR 0 0 0 0 0 0 0 0 0 0 9.56369 9.25557 0 0 0 0 0 0 8.65084 0 0 0 9.93094 10.5858 0 0 0 P07814 SYEP_HUMAN Bifunctional glutamate/proline--tRNA ligase (Bifunctional aminoacyl-tRNA synthetase) (Cell proliferation-inducing gene 32 protein) (Glutamatyl-prolyl-tRNA synthetase) [Includes: Glutamate--tRNA ligase (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS); Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase)] EPRS1 EPRS GLNS PARS QARS QPRS PIG32 Homo sapiens (Human) cellular response to insulin stimulus [GO:0032869]; cellular response to type II interferon [GO:0071346]; glutamyl-tRNA aminoacylation [GO:0006424]; negative regulation of translation [GO:0017148]; prolyl-tRNA aminoacylation [GO:0006433]; protein-containing complex assembly [GO:0065003]; regulation of long-chain fatty acid import into cell [GO:0140212]; tRNA aminoacylation for protein translation [GO:0006418] aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; GAIT complex [GO:0097452]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904] ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; GTPase binding [GO:0051020]; identical protein binding [GO:0042802]; proline-tRNA ligase activity [GO:0004827]; protein homodimerization activity [GO:0042803]; RNA stem-loop binding [GO:0035613]; zinc ion binding [GO:0008270] 0.88421 -0.13909 KNPIEKNLQMWEEMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6823 0 0 0 0 9.46318 0 0 0 0 9.6167 0 P07858 CATB_HUMAN Cathepsin B (EC 3.4.22.1) (APP secretase) (APPS) (Cathepsin B1) [Cleaved into: Cathepsin B light chain; Cathepsin B heavy chain] CTSB CPSB Homo sapiens (Human) cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; decidualization [GO:0046697]; epithelial cell differentiation [GO:0030855]; negative regulation of peptidase activity [GO:0010466]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; thyroid hormone generation [GO:0006590]; viral entry into host cell [GO:0046718] apical plasma membrane [GO:0016324]; collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; lysosome [GO:0005764]; melanosome [GO:0042470]; peptidase inhibitor complex [GO:1904090]; perinuclear region of cytoplasm [GO:0048471] collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394] 0.95196 -1.3838 DIMAEIYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.92932 0 0 0 0 0 0 0 0 P07864 LDHC_HUMAN L-lactate dehydrogenase C chain (LDH-C) (EC 1.1.1.27) (Cancer/testis antigen 32) (CT32) (LDH testis subunit) (LDH-X) LDHC LDH3 LDHX Homo sapiens (Human) ATP biosynthetic process [GO:0006754]; flagellated sperm motility [GO:0030317]; lactate biosynthetic process from pyruvate [GO:0019244]; lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]; pyruvate catabolic process [GO:0042867]; pyruvate metabolic process [GO:0006090] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; motile cilium [GO:0031514]; nucleus [GO:0005634]; oxidoreductase complex [GO:1990204] L-lactate dehydrogenase activity [GO:0004459] 0.56605 0.49183 ISGLPVTR 17.1063 0 8.2902 10.7889 0 12.5689 17.0571 0 0 0 17.4969 0 14.9744 15.1046 0 10.318 15.0813 0 14.4412 14.2501 14.6052 0 0 13.7115 15.2079 15.004 0 P07900 HS90A_HUMAN Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38) HSP90AA1 HSP90A HSPC1 HSPCA Homo sapiens (Human) activation of innate immune response [GO:0002218]; axon extension [GO:0048675]; cardiac muscle cell apoptotic process [GO:0010659]; cellular response to heat [GO:0034605]; cellular response to virus [GO:0098586]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; establishment of cell polarity [GO:0030010]; mitochondrial transport [GO:0006839]; neuron migration [GO:0001764]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of cell size [GO:0045793]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; regulation of apoptotic process [GO:0042981]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; regulation of protein localization [GO:0032880]; regulation of protein ubiquitination [GO:0031396]; regulation of protein-containing complex assembly [GO:0043254]; response to antibiotic [GO:0046677]; response to cocaine [GO:0042220]; response to cold [GO:0009409]; response to estrogen [GO:0043627]; response to heat [GO:0009408]; response to salt stress [GO:0009651]; response to unfolded protein [GO:0006986]; response to xenobiotic stimulus [GO:0009410]; skeletal muscle contraction [GO:0003009]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004] apical plasma membrane [GO:0016324]; axonal growth cone [GO:0044295]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; sperm mitochondrial sheath [GO:0097226]; sperm plasma membrane [GO:0097524] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; CTP binding [GO:0002135]; dATP binding [GO:0032564]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTP binding [GO:0005525]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; mRNA binding [GO:0003729]; nitric-oxide synthase regulator activity [GO:0030235]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; Rho GDP-dissociation inhibitor binding [GO:0051022]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; sulfonylurea receptor binding [GO:0017098]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; transmembrane transporter binding [GO:0044325]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; UTP binding [GO:0002134] 0 139.24 ADLINNLGTIAK 13.8816 13.927 13.8099 0 0 0 12.7023 11.145 12.3546 13.9422 13.2917 12.7695 10.3537 10.5936 10.2212 0 9.88929 11.7761 12.5206 12.6307 12.0624 11.2733 10.9292 10.4464 10.3726 10.6861 10.4205 P07902 GALT_HUMAN Galactose-1-phosphate uridylyltransferase (Gal-1-P uridylyltransferase) (EC 2.7.7.12) (UDP-glucose--hexose-1-phosphate uridylyltransferase) GALT Homo sapiens (Human) galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; UDP-glucose catabolic process [GO:0006258]; UDP-glucose metabolic process [GO:0006011] cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794] UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270] 0.88722 -0.3438 DLTPEQAAER 0 0 0 0 0 0 0 0 9.9443 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P07910 HNRPC_HUMAN Heterogeneous nuclear ribonucleoproteins C1/C2 (hnRNP C1/C2) HNRNPC HNRPC Homo sapiens (Human) "3'-UTR-mediated mRNA stabilization [GO:0070935]; chromatin remodeling [GO:0006338]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of telomere maintenance via telomerase [GO:0032211]; osteoblast differentiation [GO:0001649]; RNA splicing [GO:0008380]" actin cytoskeleton [GO:0015629]; catalytic step 2 spliceosome [GO:0071013]; chromatin [GO:0000785]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697] identical protein binding [GO:0042802]; mRNA 3'-UTR binding [GO:0003730]; N6-methyladenosine-containing RNA binding [GO:1990247]; nucleosomal DNA binding [GO:0031492]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; telomerase RNA binding [GO:0070034] 0 14.485 GFAFVQYVNER 9.19957 9.29802 9.34685 0 0 11.8131 10.0587 10.0341 10.2063 9.97528 10.4724 10.3893 10.526 10.7248 12.1784 11.8889 12.7614 12.816 0 8.37634 9.75672 8.54817 8.61787 0 13.3246 11.9305 10.8549 P07911 UROM_HUMAN "Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form]" UMOD Homo sapiens (Human) antibacterial innate immune response [GO:0140367]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; cellular defense response [GO:0006968]; cellular response to unfolded protein [GO:0034620]; chaperone-mediated protein folding [GO:0061077]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; intracellular calcium ion homeostasis [GO:0006874]; intracellular chloride ion homeostasis [GO:0030644]; intracellular phosphate ion homeostasis [GO:0030643]; intracellular sodium ion homeostasis [GO:0006883]; juxtaglomerular apparatus development [GO:0072051]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell population proliferation [GO:0008285]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to lipopolysaccharide [GO:0032496]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918] apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; ciliary membrane [GO:0060170]; cilium [GO:0005929]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extrinsic component of membrane [GO:0019898]; Golgi lumen [GO:0005796]; membrane [GO:0016020]; spindle pole [GO:0000922] calcium ion binding [GO:0005509]; IgG binding [GO:0019864] 0.87601 -0.0065343 ACAHWSGHCCLWDASVQVK 0 0 0 0 0 0 10.1279 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P07942 LAMB1_HUMAN Laminin subunit beta-1 (Laminin B1 chain) (Laminin-1 subunit beta) (Laminin-10 subunit beta) (Laminin-12 subunit beta) (Laminin-2 subunit beta) (Laminin-6 subunit beta) (Laminin-8 subunit beta) LAMB1 Homo sapiens (Human) cell adhesion [GO:0007155]; endodermal cell differentiation [GO:0035987]; neuron projection development [GO:0031175]; neuronal-glial interaction involved in cerebral cortex radial glia guided migration [GO:0021812]; odontogenesis [GO:0042476]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of basement membrane organization [GO:0110011]; substrate adhesion-dependent cell spreading [GO:0034446] basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; laminin-1 complex [GO:0005606]; laminin-10 complex [GO:0043259]; laminin-2 complex [GO:0005607]; laminin-8 complex [GO:0043257]; perinuclear region of cytoplasm [GO:0048471]; protein complex involved in cell-matrix adhesion [GO:0098637] extracellular matrix structural constituent [GO:0005201]; structural molecule activity [GO:0005198] 0 80.446 AAQNSGEAEYIEK 13.9059 13.9537 13.8921 9.03681 10.2515 10.7703 14.0028 14.2368 14.1486 13.7413 13.7379 13.2697 10.812 11.8362 11.4999 13.0502 12.4732 12.4991 12.0599 10.9067 10.7876 11.0339 9.26857 9.25321 11.5848 12.9935 11.4949 P07948 LYN_HUMAN Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn) LYN JTK8 Homo sapiens (Human) adaptive immune response [GO:0002250]; B cell homeostasis [GO:0001782]; B cell receptor signaling pathway [GO:0050853]; C-X-C chemokine receptor CXCR4 signaling pathway [GO:0038159]; cellular response to extracellular stimulus [GO:0031668]; cellular response to heat [GO:0034605]; cellular response to retinoic acid [GO:0071300]; dendritic cell differentiation [GO:0097028]; DNA damage response [GO:0006974]; eosinophil differentiation [GO:0030222]; ephrin receptor signaling pathway [GO:0048013]; erythrocyte differentiation [GO:0030218]; Fc receptor mediated inhibitory signaling pathway [GO:0002774]; Fc receptor mediated stimulatory signaling pathway [GO:0002431]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; hematopoietic progenitor cell differentiation [GO:0002244]; histamine secretion by mast cell [GO:0002553]; immune response-regulating cell surface receptor signaling pathway [GO:0002768]; innate immune response [GO:0045087]; interleukin-5-mediated signaling pathway [GO:0038043]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of immune response [GO:0050777]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of intracellular signal transduction [GO:1902532]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of mast cell proliferation [GO:0070667]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; neuron projection development [GO:0031175]; oligodendrocyte development [GO:0014003]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet degranulation [GO:0002576]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060369]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of mast cell proliferation [GO:0070668]; positive regulation of neuron projection development [GO:0010976]; positive regulation of oligodendrocyte progenitor proliferation [GO:0070447]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of stress-activated protein kinase signaling cascade [GO:0070304]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of B cell apoptotic process [GO:0002902]; regulation of B cell receptor signaling pathway [GO:0050855]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cytokine production [GO:0001817]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of erythrocyte differentiation [GO:0045646]; regulation of mast cell activation [GO:0033003]; regulation of mast cell degranulation [GO:0043304]; regulation of monocyte chemotaxis [GO:0090025]; regulation of platelet aggregation [GO:0090330]; regulation of protein phosphorylation [GO:0001932]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to carbohydrate [GO:0009743]; response to hormone [GO:0009725]; response to insulin [GO:0032868]; response to organic cyclic compound [GO:0014070]; response to sterol depletion [GO:0006991]; response to toxic substance [GO:0009636]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; tolerance induction to self antigen [GO:0002513]; toll-like receptor 4 signaling pathway [GO:0034142]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] "adherens junction [GO:0005912]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; integrin alpha2-beta1 complex [GO:0034666]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; membrane raft [GO:0045121]; mitochondrial crista [GO:0030061]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]" ATP binding [GO:0005524]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; ephrin receptor binding [GO:0046875]; gamma-tubulin binding [GO:0043015]; glycosphingolipid binding [GO:0043208]; integrin binding [GO:0005178]; kinase activity [GO:0016301]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; phosphorylation-dependent protein binding [GO:0140031]; platelet-derived growth factor receptor binding [GO:0005161]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH3 domain binding [GO:0017124]; signaling receptor binding [GO:0005102]; transmembrane transporter binding [GO:0044325]; ubiquitin protein ligase binding [GO:0031625] 0.9633 -2.6556 TNADVMTALSQGYRMPR 0 8.63771 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.28103 8.75836 0 0 0 0 0 0 P07949 RET_HUMAN Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] RET CDHF12 CDHR16 PTC RET51 Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; axon guidance [GO:0007411]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; lymphocyte migration into lymphoid organs [GO:0097021]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; posterior midgut development [GO:0007497]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] axon [GO:0030424]; dendrite [GO:0030425]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; plasma membrane protein complex [GO:0098797]; receptor complex [GO:0043235] ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; protein tyrosine kinase activity [GO:0004713]; signaling receptor activity [GO:0038023]; transmembrane receptor protein tyrosine kinase activity [GO:0004714] 0.92393 -1.1691 DLEKMMVKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.0222 0 0 P07954 FUMH_HUMAN "Fumarate hydratase, mitochondrial (Fumarase) (HsFH) (EC 4.2.1.2)" FH Homo sapiens (Human) DNA damage response [GO:0006974]; DNA repair [GO:0006281]; fumarate metabolic process [GO:0006106]; homeostasis of number of cells within a tissue [GO:0048873]; malate metabolic process [GO:0006108]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of arginine metabolic process [GO:0000821]; tricarboxylic acid cycle [GO:0006099]; urea cycle [GO:0000050] chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]; tricarboxylic acid cycle enzyme complex [GO:0045239] fumarate hydratase activity [GO:0004333]; histone binding [GO:0042393] 0.91372 -0.7831 IGGVTER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.14611 0 P07988 PSPB_HUMAN Pulmonary surfactant-associated protein B (SP-B) (18 kDa pulmonary-surfactant protein) (6 kDa protein) (Pulmonary surfactant-associated proteolipid SPL(Phe)) SFTPB SFTP3 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; respiratory gaseous exchange by respiratory system [GO:0007585]; sphingolipid metabolic process [GO:0006665] alveolar lamellar body [GO:0097208]; clathrin-coated endocytic vesicle [GO:0045334]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lamellar body [GO:0042599]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; multivesicular body lumen [GO:0097486] 0.8294 0.20942 SPTGEWLPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4982 0 0 0 P07992 ERCC1_HUMAN DNA excision repair protein ERCC-1 ERCC1 Homo sapiens (Human) cell population proliferation [GO:0008283]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; embryonic organ development [GO:0048568]; insulin-like growth factor receptor signaling pathway [GO:0048009]; interstrand cross-link repair [GO:0036297]; isotype switching [GO:0045190]; male gonad development [GO:0008584]; mitotic recombination [GO:0006312]; multicellular organism growth [GO:0035264]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of telomere maintenance [GO:0032205]; nucleotide-excision repair [GO:0006289]; oogenesis [GO:0048477]; positive regulation of t-circle formation [GO:1904431]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; post-embryonic hemopoiesis [GO:0035166]; pyrimidine dimer repair by nucleotide-excision repair [GO:0000720]; replicative senescence [GO:0090399]; response to cadmium ion [GO:0046686]; response to immobilization stress [GO:0035902]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to sucrose [GO:0009744]; response to X-ray [GO:0010165]; spermatogenesis [GO:0007283]; syncytium formation [GO:0006949]; t-circle formation [GO:0090656]; telomeric DNA-containing double minutes formation [GO:0061819]; UV protection [GO:0009650]; UV-damage excision repair [GO:0070914] "chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; ERCC4-ERCC1 complex [GO:0070522]; nucleoplasm [GO:0005654]; nucleotide-excision repair complex [GO:0000109]; nucleotide-excision repair factor 1 complex [GO:0000110]" damaged DNA binding [GO:0003684]; promoter-specific chromatin binding [GO:1990841]; single-stranded DNA binding [GO:0003697]; TFIID-class transcription factor complex binding [GO:0001094] 0.80864 0.22873 YHNLHPDYIHGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.1875 0 0 0 P07996 TSP1_HUMAN Thrombospondin-1 (Glycoprotein G) THBS1 TSP TSP1 Homo sapiens (Human) apoptotic process [GO:0006915]; behavioral response to pain [GO:0048266]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to growth factor stimulus [GO:0071363]; cellular response to heat [GO:0034605]; cellular response to tumor necrosis factor [GO:0071356]; chronic inflammatory response [GO:0002544]; engulfment of apoptotic cell [GO:0043652]; immune response [GO:0006955]; inflammatory response [GO:0006954]; negative regulation of angiogenesis [GO:0016525]; negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002581]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903588]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of dendritic cell antigen processing and presentation [GO:0002605]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of long-chain fatty acid import across plasma membrane [GO:0010748]; negative regulation of nitric oxide mediated signal transduction [GO:0010751]; negative regulation of plasminogen activation [GO:0010757]; negative regulation of sprouting angiogenesis [GO:1903671]; peptide cross-linking [GO:0018149]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood coagulation [GO:0030194]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemotaxis [GO:0050921]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of macrophage activation [GO:0043032]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of transforming growth factor beta1 production [GO:0032914]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor production [GO:0032760]; response to calcium ion [GO:0051592]; response to endoplasmic reticulum stress [GO:0034976]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to magnesium ion [GO:0032026]; response to mechanical stimulus [GO:0009612]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]; response to unfolded protein [GO:0006986]; response to xenobiotic stimulus [GO:0009410]; sprouting angiogenesis [GO:0002040] cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; sarcoplasmic reticulum [GO:0016529]; secretory granule [GO:0030141] calcium ion binding [GO:0005509]; collagen V binding [GO:0070052]; endopeptidase inhibitor activity [GO:0004866]; extracellular matrix structural constituent [GO:0005201]; fibrinogen binding [GO:0070051]; fibroblast growth factor binding [GO:0017134]; fibronectin binding [GO:0001968]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; low-density lipoprotein particle binding [GO:0030169]; phosphatidylserine binding [GO:0001786]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; proteoglycan binding [GO:0043394]; transforming growth factor beta binding [GO:0050431] 0.56368 0.50482 DLASIAR 10.9674 0 0 0 0 12.3777 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.7602 0 0 0 P08047 SP1_HUMAN Transcription factor Sp1 SP1 TSFP1 Homo sapiens (Human) cellular response to estrogen stimulus [GO:0071391]; cellular response to insulin stimulus [GO:0032869]; cellular response to wortmannin [GO:1904568]; cellular response to zinc ion starvation [GO:0034224]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of hydrogen sulfide biosynthetic process [GO:1904828]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; response to hydroperoxide [GO:0033194]; rhythmic process [GO:0048511] chromatin [GO:0000785]; cytoplasm [GO:0005737]; euchromatin [GO:0000791]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; transcription repressor complex [GO:0017053] "bHLH transcription factor binding [GO:0043425]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; double-stranded DNA binding [GO:0003690]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]; transcription coregulator binding [GO:0001221]" 0.95881 -1.7161 SDELQRHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5654 0 0 0 0 0 0 0 P08123 CO1A2_HUMAN Collagen alpha-2(I) chain (Alpha-2 type I collagen) COL1A2 Homo sapiens (Human) blood vessel development [GO:0001568]; bone mineralization [GO:0030282]; cellular response to amino acid stimulus [GO:0071230]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; extracellular matrix assembly [GO:0085029]; extracellular matrix organization [GO:0030198]; odontogenesis [GO:0042476]; protein heterotrimerization [GO:0070208]; regulation of blood pressure [GO:0008217]; Rho protein signal transduction [GO:0007266]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; transforming growth factor beta receptor signaling pathway [GO:0007179] collagen type I trimer [GO:0005584]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; platelet-derived growth factor binding [GO:0048407]; protease binding [GO:0002020]; protein-macromolecule adaptor activity [GO:0030674]; SMAD binding [GO:0046332] 0.72686 0.35172 FTYTVLVDGCSK 0 0 0 0 0 0 10.6398 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2615 0 0 0 0 0 0 P08133 ANXA6_HUMAN Annexin A6 (67 kDa calelectrin) (Annexin VI) (Annexin-6) (Calphobindin-II) (CPB-II) (Chromobindin-20) (Lipocortin VI) (Protein III) (p68) (p70) ANXA6 ANX6 Homo sapiens (Human) apoptotic signaling pathway [GO:0097190]; growth plate cartilage chondrocyte differentiation [GO:0003418]; mitochondrial calcium ion homeostasis [GO:0051560]; monoatomic ion transmembrane transport [GO:0034220]; negative regulation of sequestering of calcium ion [GO:0051283]; neural crest cell migration [GO:0001755]; plasma membrane repair [GO:0001778]; regulation of muscle contraction [GO:0006937] collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; melanosome [GO:0042470]; membrane [GO:0016020]; mitochondrion [GO:0005739]; perinuclear region of cytoplasm [GO:0048471] actin filament binding [GO:0051015]; calcium channel activity [GO:0005262]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; cholesterol binding [GO:0015485]; chondroitin sulfate binding [GO:0035374]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; ligand-gated monoatomic ion channel activity [GO:0015276]; lipid binding [GO:0008289]; phosphatidylserine binding [GO:0001786] 0.93214 -1.2742 EIKDAISGIGTDEK 12.2392 0 0 0 11.366 0 12.8668 0 0 0 0 0 11.1847 0 11.2886 0 0 0 0 0 9.34576 0 0 0 8.66701 0 0 P08138 TNR16_HUMAN Tumor necrosis factor receptor superfamily member 16 (Gp80-LNGFR) (Low affinity neurotrophin receptor p75NTR) (Low-affinity nerve growth factor receptor) (NGF receptor) (p75 ICD) (CD antigen CD271) NGFR TNFRSF16 Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; axon guidance [GO:0007411]; cellular response to amyloid-beta [GO:1904646]; central nervous system development [GO:0007417]; circadian regulation of gene expression [GO:0032922]; detection of temperature stimulus [GO:0016048]; dorsal aorta development [GO:0035907]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast proliferation [GO:0048144]; glucose homeostasis [GO:0042593]; hair follicle morphogenesis [GO:0031069]; intracellular glucose homeostasis [GO:0001678]; intracellular protein transport [GO:0006886]; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903588]; negative regulation of cell migration [GO:0030336]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of hair follicle development [GO:0051799]; nerve development [GO:0021675]; neuron apoptotic process [GO:0051402]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of odontogenesis of dentin-containing tooth [GO:0042488]; positive regulation of protein localization to nucleus [GO:1900182]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; Rho protein signal transduction [GO:0007266] cell surface [GO:0009986]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endosome [GO:0005768]; extracellular region [GO:0005576]; growth cone [GO:0030426]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; nucleoplasm [GO:0005654]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793] amyloid-beta binding [GO:0001540]; calmodulin binding [GO:0005516]; coreceptor activity [GO:0015026]; death receptor activity [GO:0005035]; nerve growth factor binding [GO:0048406]; neurotrophin binding [GO:0043121]; signaling receptor activity [GO:0038023]; small GTPase binding [GO:0031267]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625] 0.29324 0.81836 GAGATGR 0 0 0 10.1179 8.8464 0 0 0 0 0 0 0 0 0 0 0 0 0 9.21165 0 10.9641 11.2956 10.9667 0 0 9.11749 0 P08173 ACM4_HUMAN Muscarinic acetylcholine receptor M4 CHRM4 Homo sapiens (Human) "adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway [GO:0007197]; cell surface receptor signaling pathway [GO:0007166]; chemical synaptic transmission [GO:0007268]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; regulation of locomotion [GO:0040012]; signal transduction [GO:0007165]" dendrite [GO:0030425]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202] G protein-coupled acetylcholine receptor activity [GO:0016907]; G protein-coupled serotonin receptor activity [GO:0004993] 0.87723 -0.005505 LVTSSSHNR 0 0 0 0 0 0 0 0 0 9.61978 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P08195 4F2_HUMAN 4F2 cell-surface antigen heavy chain (4F2hc) (4F2 heavy chain antigen) (Lymphocyte activation antigen 4F2 large subunit) (Solute carrier family 3 member 2) (CD antigen CD98) SLC3A2 MDU1 Homo sapiens (Human) amino acid transport [GO:0006865]; calcium ion transport [GO:0006816]; carbohydrate metabolic process [GO:0005975]; isoleucine transport [GO:0015818]; L-alanine import across plasma membrane [GO:1904273]; L-histidine transport [GO:1902024]; L-leucine import across plasma membrane [GO:1903801]; leucine import across plasma membrane [GO:0098713]; leucine transport [GO:0015820]; methionine transport [GO:0015821]; phenylalanine transport [GO:0015823]; proline transport [GO:0015824]; response to exogenous dsRNA [GO:0043330]; thyroid hormone transport [GO:0070327]; tryptophan transport [GO:0015827]; tyrosine transport [GO:0015828]; valine transport [GO:0015829]; viral entry into host cell [GO:0046718] amino acid transport complex [GO:1990184]; anchoring junction [GO:0070161]; apical plasma membrane [GO:0016324]; apical pole of neuron [GO:0044225]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; lysosomal membrane [GO:0005765]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; synapse [GO:0045202] aromatic amino acid transmembrane transporter activity [GO:0015173]; cadherin binding [GO:0045296]; calcium:sodium antiporter activity [GO:0005432]; double-stranded RNA binding [GO:0003725]; L-alanine transmembrane transporter activity [GO:0015180]; L-leucine transmembrane transporter activity [GO:0015190]; neutral L-amino acid transmembrane transporter activity [GO:0015175]; RNA binding [GO:0003723] 0 4.1584 ADLLLSTQPGREEGSPLELER 0 0 0 0 0 0 0 8.59376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P08236 BGLR_HUMAN Beta-glucuronidase (EC 3.2.1.31) (Beta-G1) GUSB Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate catabolic process [GO:0030207]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; heparan sulfate proteoglycan catabolic process [GO:0030200]; hyaluronan catabolic process [GO:0030214] azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020] beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102] 0.56153 0.53319 MVIAHTK 0 0 0 0 0 0 0 0 0 10.0877 10.242 10.3037 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P08237 PFKAM_HUMAN "ATP-dependent 6-phosphofructokinase, muscle type (ATP-PFK) (PFK-M) (EC 2.7.1.11) (6-phosphofructokinase type A) (Phosphofructo-1-kinase isozyme A) (PFK-A) (Phosphohexokinase)" PFKM PFKX Homo sapiens (Human) "canonical glycolysis [GO:0061621]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose 6-phosphate metabolic process [GO:0006002]; glucose homeostasis [GO:0042593]; glycogen catabolic process [GO:0005980]; glycolysis from storage polysaccharide through glucose-1-phosphate [GO:0093001]; glycolytic process [GO:0006096]; glycolytic process through fructose-6-phosphate [GO:0061615]; muscle cell cellular homeostasis [GO:0046716]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription by RNA polymerase II [GO:0045944]" 6-phosphofructokinase complex [GO:0005945]; apical plasma membrane [GO:0016324]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; sperm principal piece [GO:0097228] 6-phosphofructokinase activity [GO:0003872]; AMP binding [GO:0016208]; ATP binding [GO:0005524]; fructose binding [GO:0070061]; fructose-6-phosphate binding [GO:0070095]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029] 0.96345 -2.1159 GGTPSAFDR 0 0 0 0 0 0 0 0 11.1507 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P08238 HS90B_HUMAN Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) HSP90AB1 HSP90B HSPC2 HSPCB Homo sapiens (Human) axon extension [GO:0048675]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated protein complex assembly [GO:0051131]; establishment of cell polarity [GO:0030010]; negative regulation of apoptotic process [GO:0043066]; negative regulation of proteasomal protein catabolic process [GO:1901799]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein metabolic process [GO:0051248]; negative regulation of transforming growth factor beta activation [GO:1901389]; placenta development [GO:0001890]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cyclin-dependent protein kinase activity [GO:1904031]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; regulation of cell cycle [GO:0051726]; regulation of protein localization [GO:0032880]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; supramolecular fiber organization [GO:0097435]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; virion attachment to host cell [GO:0019062] aryl hydrocarbon receptor complex [GO:0034751]; axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; dynein axonemal particle [GO:0120293]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; HSP90-CDC37 chaperone complex [GO:1990565]; melanosome [GO:0042470]; membrane [GO:0016020]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein binding [GO:0043008]; ATP-dependent protein folding chaperone [GO:0140662]; cadherin binding [GO:0045296]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; double-stranded RNA binding [GO:0003725]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; histone methyltransferase binding [GO:1990226]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; peptide binding [GO:0042277]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein kinase regulator activity [GO:0019887]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082] 0 304.37 ADLINNLGTIAK 15.4256 15.577 15.371 10.2515 11.2653 10.0511 14.7989 14.8244 14.7198 15.7748 15.6546 15.7644 14.446 14.4357 14.4741 14.8044 14.8151 14.639 14.7464 14.9181 15.0796 14.3761 14.1352 13.8085 15.6473 15.3701 15.1291 P08243 ASNS_HUMAN Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) (Cell cycle control protein TS11) (Glutamine-dependent asparagine synthetase) ASNS TS11 Homo sapiens (Human) asparagine biosynthetic process [GO:0006529]; cellular response to glucose starvation [GO:0042149]; glutamine metabolic process [GO:0006541]; L-asparagine biosynthetic process [GO:0070981]; negative regulation of apoptotic process [GO:0043066]; positive regulation of mitotic cell cycle [GO:0045931] cytosol [GO:0005829] asparagine synthase (glutamine-hydrolyzing) activity [GO:0004066]; ATP binding [GO:0005524] 0.96775 -2.7933 EAFSDGITSVK 0 0 0 0 0 0 0 0 0 0 9.44191 10.5677 0 0 9.84973 0 0 0 0 0 0 0 0 0 0 0 0 P08247 SYPH_HUMAN Synaptophysin (Major synaptic vesicle protein p38) SYP Homo sapiens (Human) cellular response to organic substance [GO:0071310]; endocytosis [GO:0006897]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of opioid receptor signaling pathway [GO:2000474]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic vesicle exocytosis [GO:2000300]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle maturation [GO:0016188]; synaptic vesicle membrane organization [GO:0048499] excitatory synapse [GO:0060076]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; presynaptic active zone [GO:0048786]; presynaptic membrane [GO:0042734]; Schaffer collateral - CA1 synapse [GO:0098685]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195] cholesterol binding [GO:0015485]; identical protein binding [GO:0042802]; SH2 domain binding [GO:0042169] 0.96173 -2.5603 EPLGFVK 0 0 0 11.3045 0 11.3153 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.6069 11.6644 11.5507 0 0 0 P08254 MMP3_HUMAN Stromelysin-1 (SL-1) (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1) MMP3 STMY1 Homo sapiens (Human) cellular response to nitric oxide [GO:0071732]; cellular response to UV-A [GO:0071492]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; innate immune response [GO:0045087]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein-containing complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645] cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634] endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270] 0.89951 -0.61209 GEDTSMNLVQK 0 0 0 0 9.76852 0 0 0 0 0 0 0 0 0 9.78622 0 0 0 0 0 0 0 0 8.72035 0 0 0 P08319 ADH4_HUMAN All-trans-retinol dehydrogenase [NAD(+)] ADH4 (EC 1.1.1.105) (Alcohol dehydrogenase 2) (Alcohol dehydrogenase 4) (Alcohol dehydrogenase class II pi chain) ADH4 ADH2 Homo sapiens (Human) alcohol catabolic process [GO:0046164]; alcohol metabolic process [GO:0006066]; cellular aldehyde metabolic process [GO:0006081]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; quinone metabolic process [GO:1901661]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572] cytosol [GO:0005829]; nucleoplasm [GO:0005654] "alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; all-trans retinal binding [GO:0005503]; benzaldehyde dehydrogenase [NAD(P)+] activity [GO:0019115]; NAD binding [GO:0051287]; NAD-retinol dehydrogenase activity [GO:0004745]; NADPH:quinone reductase activity [GO:0003960]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; retinol binding [GO:0019841]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]" 0.88446 -0.1308 IIGIDINSEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.66388 0 0 0 0 8.82295 0 0 0 0 0 0 0 P08476 INHBA_HUMAN Inhibin beta A chain (Activin beta-A chain) (Erythroid differentiation protein) (EDF) INHBA Homo sapiens (Human) activin receptor signaling pathway [GO:0032924]; BMP signaling pathway [GO:0030509]; cardiac fibroblast cell development [GO:0060936]; cell differentiation [GO:0030154]; cell surface receptor signaling pathway [GO:0007166]; cell-cell signaling [GO:0007267]; cellular response to angiotensin [GO:1904385]; cellular response to cholesterol [GO:0071397]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; defense response [GO:0006952]; endodermal cell differentiation [GO:0035987]; erythrocyte differentiation [GO:0030218]; extrinsic apoptotic signaling pathway [GO:0097191]; eyelid development in camera-type eye [GO:0061029]; GABAergic neuron differentiation [GO:0097154]; hair follicle development [GO:0001942]; hematopoietic progenitor cell differentiation [GO:0002244]; hemoglobin biosynthetic process [GO:0042541]; male gonad development [GO:0008584]; mesodermal cell differentiation [GO:0048333]; multicellular organism aging [GO:0010259]; negative regulation of B cell differentiation [GO:0045578]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of follicle-stimulating hormone secretion [GO:0046882]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of macrophage differentiation [GO:0045650]; negative regulation of phosphorylation [GO:0042326]; negative regulation of type II interferon production [GO:0032689]; nervous system development [GO:0007399]; odontogenesis [GO:0042476]; ovarian follicle development [GO:0001541]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of follicle-stimulating hormone secretion [GO:0046881]; positive regulation of gene expression [GO:0010628]; positive regulation of ovulation [GO:0060279]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; progesterone secretion [GO:0042701]; regulation of follicle-stimulating hormone secretion [GO:0046880]; regulation of transcription by RNA polymerase II [GO:0006357]; response to xenobiotic stimulus [GO:0009410]; roof of mouth development [GO:0060021]; SMAD protein signal transduction [GO:0060395]; striatal medium spiny neuron differentiation [GO:0021773]; transcription by RNA polymerase II [GO:0006366] activin A complex [GO:0043509]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; inhibin A complex [GO:0043512]; perinuclear region of cytoplasm [GO:0048471] cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; peptide hormone binding [GO:0017046]; protein-containing complex binding [GO:0044877]; type II activin receptor binding [GO:0070699] 0.89857 -0.59916 DIQNMIVEECGCS 0 0 0 0 0 0 0 0 0 0 9.18443 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.3292 P08559 ODPA_HUMAN "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (EC 1.2.4.1) (PDHE1-A type I)" PDHA1 PHE1A Homo sapiens (Human) acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; tricarboxylic acid cycle [GO:0006099] mitochondrial matrix [GO:0005759]; mitochondrial pyruvate dehydrogenase complex [GO:0005967]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254] pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase (NAD+) activity [GO:0034604] 0.73438 0.32864 EILAELTGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.5386 0 0 0 0 0 0 0 P08572 CO4A2_HUMAN Collagen alpha-2(IV) chain [Cleaved into: Canstatin] COL4A2 Homo sapiens (Human) aging [GO:0007568]; angiogenesis [GO:0001525]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; DNA-templated transcription [GO:0006351]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; negative regulation of angiogenesis [GO:0016525]; response to activity [GO:0014823] basement membrane [GO:0005604]; collagen type IV trimer [GO:0005587]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615] extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020] 0.88408 -0.25091 GDEGPMGLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.5475 0 0 0 0 0 0 0 0 0 0 0 P08574 CY1_HUMAN "Cytochrome c1, heme protein, mitochondrial (EC 7.1.1.8) (Complex III subunit 4) (Complex III subunit IV) (Cytochrome b-c1 complex subunit 4) (Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit) (Cytochrome c-1)" CYC1 Homo sapiens (Human) "cellular respiration [GO:0045333]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; response to glucagon [GO:0033762]" membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; nucleus [GO:0005634] heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121] 0.9555 -1.5607 TPQAVALSSK 0 0 10.481 0 0 0 9.99365 9.22195 0 10.3844 0 10.724 0 0 0 10.3088 0 9.80009 0 0 0 0 0 0 0 0 0 P08575 PTPRC_HUMAN Receptor-type tyrosine-protein phosphatase C (EC 3.1.3.48) (Leukocyte common antigen) (L-CA) (T200) (CD antigen CD45) PTPRC CD45 Homo sapiens (Human) alpha-beta T cell proliferation [GO:0046633]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; B cell receptor signaling pathway [GO:0050853]; bone marrow development [GO:0048539]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell cycle phase transition [GO:0044770]; cell surface receptor signaling pathway [GO:0007166]; cellular response to extracellular stimulus [GO:0031668]; defense response to virus [GO:0051607]; dephosphorylation [GO:0016311]; DN2 thymocyte differentiation [GO:1904155]; extrinsic apoptotic signaling pathway [GO:0097191]; gamma-delta T cell differentiation [GO:0042492]; hematopoietic progenitor cell differentiation [GO:0002244]; heterotypic cell-cell adhesion [GO:0034113]; leukocyte cell-cell adhesion [GO:0007159]; MAPK cascade [GO:0000165]; natural killer cell differentiation [GO:0001779]; negative regulation of cell adhesion involved in substrate-bound cell migration [GO:0006933]; negative regulation of cytokine-mediated signaling pathway [GO:0001960]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein tyrosine kinase activity [GO:0061099]; negative regulation of T cell mediated cytotoxicity [GO:0001915]; negative thymic T cell selection [GO:0045060]; peptidyl-tyrosine phosphorylation [GO:0018108]; plasma membrane raft distribution [GO:0044855]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of antigen receptor-mediated signaling pathway [GO:0050857]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [GO:1905451]; positive regulation of gamma-delta T cell differentiation [GO:0045588]; positive regulation of hematopoietic stem cell migration [GO:2000473]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein tyrosine phosphatase activity [GO:1903615]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tumor necrosis factor production [GO:0032760]; positive thymic T cell selection [GO:0045059]; protein autophosphorylation [GO:0046777]; protein dephosphorylation [GO:0006470]; regulation of cell cycle [GO:0051726]; regulation of gene expression [GO:0010468]; regulation of interleukin-8 production [GO:0032677]; regulation of phagocytosis [GO:0050764]; regulation of protein tyrosine kinase activity [GO:0061097]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; release of sequestered calcium ion into cytosol [GO:0051209]; response to gamma radiation [GO:0010332]; stem cell development [GO:0048864]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852] bleb [GO:0032059]; cell surface [GO:0009986]; cytoplasmic side of plasma membrane [GO:0009898]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; membrane microdomain [GO:0098857]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667] ankyrin binding [GO:0030506]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; signaling receptor binding [GO:0005102]; spectrin binding [GO:0030507]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001] 0.96801 -2.9251 DCLNLDKNLIK 11.6564 0 0 0 0 0 0 0 0 12.341 12.173 12.4983 0 0 0 0 0 0 0 10.0537 0 0 0 0 0 0 0 P08581 MET_HUMAN Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met) MET Homo sapiens (Human) branching morphogenesis of an epithelial tube [GO:0048754]; cell migration [GO:0016477]; cell surface receptor signaling pathway [GO:0007166]; endothelial cell morphogenesis [GO:0001886]; establishment of skin barrier [GO:0061436]; liver development [GO:0001889]; negative regulation of autophagy [GO:0010507]; negative regulation of guanyl-nucleotide exchange factor activity [GO:1905098]; negative regulation of hydrogen peroxide-mediated programmed cell death [GO:1901299]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; nervous system development [GO:0007399]; neuron differentiation [GO:0030182]; pancreas development [GO:0031016]; phagocytosis [GO:0006909]; positive chemotaxis [GO:0050918]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of kinase activity [GO:0033674]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; semaphorin-plexin signaling pathway [GO:0071526]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] basal plasma membrane [GO:0009925]; cell surface [GO:0009986]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] ATP binding [GO:0005524]; hepatocyte growth factor receptor activity [GO:0005008]; identical protein binding [GO:0042802]; molecular function activator activity [GO:0140677]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; semaphorin receptor activity [GO:0017154] 0.91213 -0.7524 CTVGPAMNK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0042 0 0 0 0 0 0 0 0 0 0 0 0 0 P08582 TRFM_HUMAN Melanotransferrin (Melanoma-associated antigen p97) (CD antigen CD228) MELTF MAP97 MFI2 Homo sapiens (Human) iron ion transmembrane transport [GO:0034755]; iron ion transport [GO:0006826]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of plasminogen activation [GO:0010756] cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037] iron ion binding [GO:0005506] 0.89754 -0.54952 GLLCDPNRLPPYLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6584 0 0 0 0 0 0 9.10682 0 P08588 ADRB1_HUMAN Beta-1 adrenergic receptor (Beta-1 adrenoreceptor) (Beta-1 adrenoceptor) ADRB1 ADRB1R B1AR Homo sapiens (Human) "activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; brown fat cell differentiation [GO:0050873]; diet induced thermogenesis [GO:0002024]; fear response [GO:0042596]; heat generation [GO:0031649]; negative regulation of multicellular organism growth [GO:0040015]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of GTPase activity [GO:0043547]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of the force of heart contraction by epinephrine-norepinephrine [GO:0001997]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; response to cold [GO:0009409]" early endosome [GO:0005769]; neuronal dense core vesicle [GO:0098992]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685] alpha-2A adrenergic receptor binding [GO:0031694]; beta-adrenergic receptor activity [GO:0004939]; beta1-adrenergic receptor activity [GO:0004940]; G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential [GO:0099579]; guanyl-nucleotide exchange factor activity [GO:0005085]; PDZ domain binding [GO:0030165]; protein heterodimerization activity [GO:0046982] 0.86317 0.088268 CYNDPKCCDFVTNR 0 0 0 9.07428 0 0 8.8098 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P08590 MYL3_HUMAN "Myosin light chain 3 (Cardiac myosin light chain 1) (CMLC1) (Myosin light chain 1, slow-twitch muscle B/ventricular isoform) (MLC1SB) (Ventricular myosin alkali light chain) (Ventricular myosin light chain 1) (VLCl) (Ventricular/slow twitch myosin alkali light chain) (MLC-lV/sb)" MYL3 Homo sapiens (Human) cardiac muscle contraction [GO:0060048]; positive regulation of ATP-dependent activity [GO:0032781]; regulation of striated muscle contraction [GO:0006942]; regulation of the force of heart contraction [GO:0002026]; ventricular cardiac muscle tissue morphogenesis [GO:0055010] A band [GO:0031672]; cytosol [GO:0005829]; I band [GO:0031674]; muscle myosin complex [GO:0005859]; myosin II complex [GO:0016460]; sarcomere [GO:0030017] actin monomer binding [GO:0003785]; calcium ion binding [GO:0005509]; myosin II heavy chain binding [GO:0032038]; structural constituent of muscle [GO:0008307] 0.72206 0.36025 DTGTYEDFVEGLRVFDKEGNGTVMGAELR 0 0 0 0 0 0 0 0 0 0 0 0 11.1378 0 0 0 0 0 0 0 0 9.44045 0 0 0 0 0 P08603 CFAH_HUMAN Complement factor H (H factor 1) CFH HF HF1 HF2 Homo sapiens (Human) "complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; proteolysis [GO:0006508]; regulation of complement activation [GO:0030449]; regulation of complement activation, alternative pathway [GO:0030451]; regulation of complement-dependent cytotoxicity [GO:1903659]" blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; serine-type endopeptidase complex [GO:1905370]; symbiont cell surface [GO:0106139] complement component C3b binding [GO:0001851]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802] 0.96892 -5.835 CKSSNLIILEEHLK 0 0 0 0 0 0 0 0 0 0 0 10.0037 11.043 10.658 0 0 0 0 0 10.2146 9.62224 0 0 0 0 0 0 P08620 FGF4_HUMAN Fibroblast growth factor 4 (FGF-4) (Heparin secretory-transforming protein 1) (HST) (HST-1) (HSTF-1) (Heparin-binding growth factor 4) (HBGF-4) (Transforming protein KS3) FGF4 HST HSTF1 KS3 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; apoptotic process involved in morphogenesis [GO:0060561]; cartilage condensation [GO:0001502]; cell differentiation [GO:0030154]; cell-cell signaling [GO:0007267]; cellular response to leukemia inhibitory factor [GO:1990830]; chondroblast differentiation [GO:0060591]; cranial suture morphogenesis [GO:0060363]; embryonic hindlimb morphogenesis [GO:0035116]; epithelial cell apoptotic process [GO:1904019]; fibroblast growth factor receptor signaling pathway [GO:0008543]; mesenchymal cell proliferation [GO:0010463]; negative regulation of apoptotic process [GO:0043066]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell migration [GO:0030334]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089] cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615] fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201] 0.89728 -0.52696 EAAVQSGAGDYLLGIK 9.99393 0 0 0 0 0 0 0 0 8.46197 0 0 0 9.4405 0 0 0 0 0 0 0 0 0 0 0 10.5474 0 P08621 RU17_HUMAN U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70) SNRNP70 RNPU1Z RPU1 SNRP70 U1AP1 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; negative regulation of chaperone-mediated autophagy [GO:1904715]; negative regulation of protein refolding [GO:0061084]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; regulation of ATP-dependent activity [GO:0043462]; regulation of RNA splicing [GO:0043484]" nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; U2-type prespliceosome [GO:0071004] mRNA binding [GO:0003729]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619] 0.95926 -1.7315 DRDREHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0893 0 0 0 0 0 0 P08631 HCK_HUMAN Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck) HCK Homo sapiens (Human) cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response-activating signaling pathway [GO:0002758]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte degranulation [GO:0043299]; leukocyte migration involved in immune response [GO:0002522]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; localization [GO:0051179]; mesoderm development [GO:0007498]; negative regulation of apoptotic process [GO:0043066]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of inflammatory response [GO:0050727]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801]; respiratory burst after phagocytosis [GO:0045728]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; type II interferon-mediated signaling pathway [GO:0060333] caveola [GO:0005901]; cell projection [GO:0042995]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133] ATP binding [GO:0005524]; lipid binding [GO:0008289]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102] 0.90741 -0.7328 DEERAPRMGCMK 0 0 0 0 0 0 0 0 0 11.2833 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P08648 ITA5_HUMAN Integrin alpha-5 (CD49 antigen-like family member E) (Fibronectin receptor subunit alpha) (Integrin alpha-F) (VLA-5) (CD antigen CD49e) [Cleaved into: Integrin alpha-5 heavy chain; Integrin alpha-5 light chain] ITGA5 FNRA Homo sapiens (Human) "angiogenesis [GO:0001525]; CD40 signaling pathway [GO:0023035]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by integrin [GO:0033631]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; cell-substrate junction assembly [GO:0007044]; endodermal cell differentiation [GO:0035987]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; memory [GO:0007613]; negative regulation of anoikis [GO:2000811]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; wound healing, spreading of epidermal cells [GO:0035313]" alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; integrin alpha5-beta1 complex [GO:0034674]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; ruffle [GO:0001726] calcium ion binding [GO:0005509]; epidermal growth factor receptor binding [GO:0005154]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618] 0.77529 0.2651 AGASLWGGLR 0 0 9.37415 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6432 0 0 P08651 NFIC_HUMAN Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein) NFIC NFI Homo sapiens (Human) DNA replication [GO:0006260]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] chromatin [GO:0000785]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.94075 -1.3314 ELDLYLAYFVRER 0 12.2359 0 11.0672 0 0 0 0 0 0 0 0 0 0 0 0 11.0551 0 0 9.88588 0 0 0 0 0 0 0 P08670 VIME_HUMAN Vimentin VIM Homo sapiens (Human) astrocyte development [GO:0014002]; Bergmann glial cell differentiation [GO:0060020]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to type II interferon [GO:0071346]; intermediate filament organization [GO:0045109]; lens fiber cell development [GO:0070307]; negative regulation of neuron projection development [GO:0010977]; neuron projection development [GO:0031175]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of translation [GO:0045727]; regulation of mRNA stability [GO:0043488]; SMAD protein signal transduction [GO:0060395] axon [GO:0030424]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intermediate filament [GO:0005882]; intermediate filament cytoskeleton [GO:0045111]; microtubule organizing center [GO:0005815]; nuclear matrix [GO:0016363]; peroxisome [GO:0005777]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; polysome [GO:0005844]; ribonucleoprotein complex [GO:1990904] double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; keratin filament binding [GO:1990254]; molecular adaptor activity [GO:0060090]; protein domain specific binding [GO:0019904]; scaffold protein binding [GO:0097110]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of eye lens [GO:0005212] 0 2.9979 DNLAEDIMR 0 8.54187 0 0 0 0 9.96809 0 9.71072 0 0 0 0 9.68806 0 0 0 0 0 0 0 0 0 0 0 0 0 P08686 CP21A_HUMAN Steroid 21-hydroxylase (EC 1.14.14.16) (21-OHase) (Cytochrome P-450c21) (Cytochrome P450 21) (Cytochrome P450 XXI) (Cytochrome P450-C21) (Cytochrome P450-C21B) CYP21A2 CYP21 CYP21B Homo sapiens (Human) glucocorticoid biosynthetic process [GO:0006704]; mineralocorticoid biosynthetic process [GO:0006705]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202]; sterol metabolic process [GO:0016125] endoplasmic reticulum membrane [GO:0005789] 17-hydroxyprogesterone 21-hydroxylase activity [GO:0103069]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; progesterone 21-hydroxylase activity [GO:0106309]; steroid 21-monooxygenase activity [GO:0004509]; steroid binding [GO:0005496]; steroid hydroxylase activity [GO:0008395] 0.84076 0.18186 LLWNWWK 0 0 0 0 0 0 0 0 0 10.5135 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P08708 RS17_HUMAN Small ribosomal subunit protein eS17 (40S ribosomal protein S17) RPS17 RPS17L Homo sapiens (Human) cytoplasmic translation [GO:0002181]; erythrocyte homeostasis [GO:0034101]; ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364]; translation [GO:0006412]; translational initiation [GO:0006413] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; ribosome [GO:0005840]; small-subunit processome [GO:0032040]; synapse [GO:0045202] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.0081967 2.1129 LLDFGSLSNLQVTQPTVGMNFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.94072 0 9.43854 P08709 FA7_HUMAN Coagulation factor VII (EC 3.4.21.21) (Proconvertin) (Serum prothrombin conversion accelerator) (SPCA) (Eptacog alfa) [Cleaved into: Factor VII light chain; Factor VII heavy chain] F7 Homo sapiens (Human) "activation of blood coagulation via clotting cascade [GO:0002543]; animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; blood coagulation, fibrin clot formation [GO:0072378]; blood coagulation, intrinsic pathway [GO:0007597]; circadian rhythm [GO:0007623]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; proteolysis [GO:0006508]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to anticoagulant [GO:0061476]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]; response to wounding [GO:0009611]; zymogen activation [GO:0031638]" collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; serine-type endopeptidase complex [GO:1905370]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982] calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102] 0.92656 -1.2158 IVGGKVCPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.58613 0 0 0 0 0 P08727 K1C19_HUMAN "Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)" KRT19 Homo sapiens (Human) cell differentiation involved in embryonic placenta development [GO:0060706]; epithelial cell differentiation [GO:0030855]; intermediate filament organization [GO:0045109]; Notch signaling pathway [GO:0007219]; response to estrogen [GO:0043627]; sarcomere organization [GO:0045214] apicolateral plasma membrane [GO:0016327]; cell periphery [GO:0071944]; costamere [GO:0043034]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; terminal web [GO:1990357]; Z disc [GO:0030018] structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307] 0 162.75 AALEDTLAETEAR 13.153 13.16 13.1824 0 0 0 13.9652 14.2753 14.0787 11.8934 13.0493 12.7269 12.2669 12.5423 11.9513 12.1234 13.2986 11.7164 14.7628 14.2113 14.3293 14.5426 14.4043 14.0528 16.0115 15.9676 15.747 P08729 K2C7_HUMAN "Keratin, type II cytoskeletal 7 (Cytokeratin-7) (CK-7) (Keratin-7) (K7) (Sarcolectin) (Type-II keratin Kb7)" KRT7 SCL Homo sapiens (Human) keratinization [GO:0031424] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; intermediate filament cytoskeleton [GO:0045111]; keratin filament [GO:0045095]; nucleus [GO:0005634] structural constituent of skin epidermis [GO:0030280] 0 163.82 AEAEAWYQTK 12.2091 11.8848 10.8602 0 12.4286 10.1015 13.2516 13.3424 13.2642 8.595 9.68996 9.22848 10.98 9.8664 10.3383 12.4056 12.2699 10.88 13.7993 13.7345 13.6027 12.8938 13.4549 13.1861 15.1331 14.912 14.839 P08758 ANXA5_HUMAN Annexin A5 (Anchorin CII) (Annexin V) (Annexin-5) (Calphobindin I) (CPB-I) (Endonexin II) (Lipocortin V) (Placental anticoagulant protein 4) (PP4) (Placental anticoagulant protein I) (PAP-I) (Thromboplastin inhibitor) (Vascular anticoagulant-alpha) (VAC-alpha) ANXA5 ANX5 ENX2 PP4 Homo sapiens (Human) blood coagulation [GO:0007596]; negative regulation of apoptotic process [GO:0043066]; negative regulation of coagulation [GO:0050819]; response to organic substance [GO:0010033]; signal transduction [GO:0007165] collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; membrane [GO:0016020] calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; phosphatidylserine binding [GO:0001786]; phospholipase inhibitor activity [GO:0004859]; phospholipid binding [GO:0005543] 0 13.602 ADAETLR 12.2977 11.9742 12.1103 0 8.86062 0 12.2468 11.5876 12.3284 10.0853 0 0 0 0 0 9.90884 11.3313 9.48999 10.159 9.77558 10.1262 8.63746 8.77929 0 11.5217 11.9574 11.368 P08779 K1C16_HUMAN "Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16)" KRT16 KRT16A Homo sapiens (Human) cytoskeleton organization [GO:0007010]; epithelial cell differentiation [GO:0030855]; establishment of skin barrier [GO:0061436]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intermediate filament organization [GO:0045109]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; keratinocyte migration [GO:0051546]; morphogenesis of an epithelium [GO:0002009]; negative regulation of cell migration [GO:0030336] cornified envelope [GO:0001533]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; keratin filament [GO:0045095]; nucleus [GO:0005634] structural constituent of cytoskeleton [GO:0005200] 0.42366 0.66746 ALEEANADLEVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.73055 0 0 0 0 0 0 0 P08912 ACM5_HUMAN Muscarinic acetylcholine receptor M5 CHRM5 Homo sapiens (Human) "adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway [GO:0007197]; chemical synaptic transmission [GO:0007268]; dopamine transport [GO:0015872]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; regulation of phosphatidylinositol dephosphorylation [GO:0060304]; transmission of nerve impulse [GO:0019226]" dendrite [GO:0030425]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202] G protein-coupled acetylcholine receptor activity [GO:0016907]; G protein-coupled serotonin receptor activity [GO:0004993]; phosphatidylinositol phospholipase C activity [GO:0004435] 0.9614 -2.5718 ERNQASWSSSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.35856 0 0 P08922 ROS1_HUMAN Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase) ROS1 MCF3 ROS Homo sapiens (Human) cell differentiation [GO:0030154]; columnar/cuboidal epithelial cell development [GO:0002066]; positive regulation of kinase activity [GO:0033674]; protein phosphorylation [GO:0006468]; regulation of cell growth [GO:0001558]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of TOR signaling [GO:0032006]; spermatogenesis [GO:0007283]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] membrane [GO:0016020]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] ATP binding [GO:0005524]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714] 0.92298 -1.074 CFIAFQVR 13.0854 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P08962 CD63_HUMAN CD63 antigen (Granulophysin) (Lysosomal-associated membrane protein 3) (LAMP-3) (Lysosome integral membrane protein 1) (Limp1) (Melanoma-associated antigen ME491) (OMA81H) (Ocular melanoma-associated antigen) (Tetraspanin-30) (Tspan-30) (CD antigen CD63) CD63 MLA1 TSPAN30 Homo sapiens (Human) cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; endosome to melanosome transport [GO:0035646]; pigment granule maturation [GO:0048757]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746] "azurophil granule membrane [GO:0035577]; cell surface [GO:0009986]; endosome lumen [GO:0031904]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; melanosome [GO:0042470]; multivesicular body membrane [GO:0032585]; multivesicular body, internal vesicle [GO:0097487]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; platelet dense granule membrane [GO:0031088]" 0.58939 0.46048 QQMENYPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.70938 0 0 P08F94 PKHD1_HUMAN Fibrocystin (Polycystic kidney and hepatic disease 1 protein) (Polyductin) (Tigmin) PKHD1 FCYT TIGM1 Homo sapiens (Human) branching morphogenesis of an epithelial tube [GO:0048754]; cell-cell adhesion [GO:0098609]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; epithelial cell morphogenesis [GO:0003382]; establishment of centrosome localization [GO:0051660]; establishment of mitotic spindle orientation [GO:0000132]; homeostatic process [GO:0042592]; intracellular calcium ion homeostasis [GO:0006874]; kidney development [GO:0001822]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein kinase B signaling [GO:0051898]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; regulation of cell adhesion [GO:0030155]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell-matrix adhesion [GO:0001952]; regulation of centrosome duplication [GO:0010824]; regulation of cholangiocyte proliferation [GO:1904054]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of planar polarity [GO:0090175]; regulation of TOR signaling [GO:0032006] "9+0 non-motile cilium [GO:0097731]; apical plasma membrane [GO:0016324]; centrosome [GO:0005813]; chromosome, centromeric region [GO:0000775]; ciliary basal body [GO:0036064]; cilium [GO:0005929]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; mitotic spindle [GO:0072686]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]" signaling receptor activity [GO:0038023] 0.49116 0.61778 IGSEDKPFQGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3002 0 0 0 0 0 0 0 0 0 0 10.8793 P09017 HXC4_HUMAN Homeobox protein Hox-C4 (Homeobox protein CP19) (Homeobox protein Hox-3E) HOXC4 HOX3E Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; cartilage development [GO:0051216]; embryonic skeletal system morphogenesis [GO:0048704]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; HMG box domain binding [GO:0071837]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.8725 0.037321 IMSSYLMDSNYIDPK 0 0 10.0776 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P09038 FGF2_HUMAN Fibroblast growth factor 2 (FGF-2) (Basic fibroblast growth factor) (bFGF) (Heparin-binding growth factor 2) (HBGF-2) FGF2 FGFB Homo sapiens (Human) aging [GO:0007568]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; canonical Wnt signaling pathway [GO:0060070]; cell differentiation [GO:0030154]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to mechanical stimulus [GO:0071260]; cerebellar granule cell precursor proliferation [GO:0021930]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; corticotropin hormone secreting cell differentiation [GO:0060128]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic morphogenesis [GO:0048598]; endothelial cell proliferation [GO:0001935]; ERK1 and ERK2 cascade [GO:0070371]; fibroblast growth factor receptor signaling pathway [GO:0008543]; glial cell differentiation [GO:0010001]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inner ear auditory receptor cell differentiation [GO:0042491]; inositol phosphate biosynthetic process [GO:0032958]; lung development [GO:0030324]; lymphatic endothelial cell migration [GO:1904977]; mammary gland epithelial cell differentiation [GO:0060644]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of gene expression [GO:0010629]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; neuroblast proliferation [GO:0007405]; organ induction [GO:0001759]; osteoblast differentiation [GO:0001649]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cerebellar granule cell precursor proliferation [GO:0021940]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial tube formation [GO:1905278]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of inner ear auditory receptor cell differentiation [GO:0045609]; positive regulation of lens fiber cell differentiation [GO:1902748]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuroepithelial cell differentiation [GO:1902913]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of stem cell differentiation [GO:2000738]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein kinase B signaling [GO:0043491]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903587]; regulation of cell cycle [GO:0051726]; regulation of cell migration [GO:0030334]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of retinal cell programmed cell death [GO:0046668]; release of sequestered calcium ion into cytosol [GO:0051209]; response to axon injury [GO:0048678]; signal transduction [GO:0007165]; stem cell development [GO:0048864]; stem cell proliferation [GO:0072089]; substantia nigra development [GO:0021762]; thyroid-stimulating hormone-secreting cell differentiation [GO:0060129]; transcription by RNA polymerase II [GO:0006366]; wound healing [GO:0042060] cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634] chemoattractant activity [GO:0042056]; chemokine binding [GO:0019956]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; nuclear receptor coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722] 0.88469 -0.22588 TEERPSGSRLGDRGR 0 0 0 0 13.4906 0 0 0 0 0 0 0 0 0 0 0 0 9.66685 0 0 0 0 0 0 0 0 0 P09104 ENOG_HUMAN Gamma-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Enolase 2) (Neural enolase) (Neuron-specific enolase) (NSE) ENO2 Homo sapiens (Human) canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; multicellular organismal reproductive process [GO:0048609]; negative regulation of neuron death [GO:1901215]; response to estradiol [GO:0032355]; response to xenobiotic stimulus [GO:0009410] cell cortex [GO:0005938]; cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; growth cone [GO:0030426]; membrane [GO:0016020]; membrane raft [GO:0045121]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; synaptic membrane [GO:0097060] enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; protein-containing complex binding [GO:0044877] 0 9.0537 AAVPSGASTGIYEALELR 0 0 0 9.94509 0 0 11.8665 13.7162 0 0 0 0 11.1325 11.411 0 12.6272 0 0 11.5833 0 10.5462 0 11.8946 0 12.5576 0 0 P09110 THIK_HUMAN "3-ketoacyl-CoA thiolase, peroxisomal (EC 2.3.1.16) (Acetyl-CoA C-myristoyltransferase) (EC 2.3.1.155) (Acetyl-CoA acyltransferase) (EC 2.3.1.9) (Beta-ketothiolase) (Peroxisomal 3-oxoacyl-CoA thiolase)" ACAA1 ACAA PTHIO Homo sapiens (Human) alpha-linolenic acid metabolic process [GO:0036109]; bile acid metabolic process [GO:0008206]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; phenylacetate catabolic process [GO:0010124]; very long-chain fatty acid metabolic process [GO:0000038] cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; specific granule lumen [GO:0035580] acetate CoA-transferase activity [GO:0008775]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; acetyl-CoA C-acyltransferase activity [GO:0003988]; acetyl-CoA C-myristoyltransferase activity [GO:0050633]; palmitoyl-CoA oxidase activity [GO:0016401] 0.3622 0.74882 GNPGNITSRLMEK 0 9.0617 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.88999 0 P09132 SRP19_HUMAN Signal recognition particle 19 kDa protein (SRP19) SRP19 Homo sapiens (Human) "cotranslational protein targeting to membrane [GO:0006613]; SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition [GO:0006617]" "cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; signal recognition particle [GO:0048500]; signal recognition particle, endoplasmic reticulum targeting [GO:0005786]" 7S RNA binding [GO:0008312]; RNA binding [GO:0003723] 0.40433 0.70191 FICIYPAYLNNKK 0 10.3243 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P09211 GSTP1_HUMAN Glutathione S-transferase P (EC 2.5.1.18) (GST class-pi) (GSTP1-1) GSTP1 FAEES3 GST3 Homo sapiens (Human) cellular response to lipopolysaccharide [GO:0071222]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; hepoxilin biosynthetic process [GO:0051122]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; nitric oxide storage [GO:0035732]; positive regulation of superoxide anion generation [GO:0032930]; prostaglandin metabolic process [GO:0006693]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982] dinitrosyl-iron complex binding [GO:0035731]; fatty acid binding [GO:0005504]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730] 0 19.37 AFLASPEYVNLPINGNGKQ 9.24788 9.10145 8.54705 0 0 0 11.1654 10.4289 10.4129 0 0 0 10.3498 9.56953 10.3622 9.41602 10.589 0 10.6775 9.02702 10.5949 8.98182 9.6847 9.86037 11.1651 0 11.2682 P09228 CYTT_HUMAN Cystatin-SA (Cystatin-2) (Cystatin-S5) CST2 Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cysteine-type endopeptidase activity [GO:2000117] cytoplasm [GO:0005737]; extracellular space [GO:0005615]; vesicle [GO:0031982] cysteine-type endopeptidase inhibitor activity [GO:0004869] 0.91426 -0.82529 AREQIVGGVNYFFDIEVGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.46434 0 0 0 0 0 0 P09237 MMP7_HUMAN Matrilysin (EC 3.4.24.23) (Matrin) (Matrix metalloproteinase-7) (MMP-7) (Pump-1 protease) (Uterine metalloproteinase) MMP7 MPSL1 PUMP1 Homo sapiens (Human) collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508] extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270] 0.93231 -1.2578 DLPHITVDR 8.53372 0 0 0 0 0 0 0 0 0 9.3484 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P09238 MMP10_HUMAN Stromelysin-2 (SL-2) (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) MMP10 STMY2 Homo sapiens (Human) collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; proteolysis [GO:0006508] extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270] 0.96315 -2.1507 GEYLFFKDRYFWR 0 0 0 0 0 0 0 0 0 10.1861 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P09341 GROA_HUMAN Growth-regulated alpha protein (C-X-C motif chemokine 1) (GRO-alpha(1-73)) (Melanoma growth stimulatory activity) (MGSA) (Neutrophil-activating protein 3) (NAP-3) [Cleaved into: GRO-alpha(4-73); GRO-alpha(5-73); GRO-alpha(6-73)] CXCL1 GRO GRO1 GROA MGSA SCYB1 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; killing of cells of another organism [GO:0031640]; negative regulation of cell population proliferation [GO:0008285]; nervous system development [GO:0007399]; neutrophil chemotaxis [GO:0030593]; signal transduction [GO:0007165] extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724] chemokine activity [GO:0008009]; CXCR chemokine receptor binding [GO:0045236]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; signaling receptor binding [GO:0005102] 0.78492 0.25656 AAGASVATELR 0 0 0 0 0 0 0 0 0 0 0 11.0065 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P09455 RET1_HUMAN Retinol-binding protein 1 (Cellular retinol-binding protein) (CRBP) (Cellular retinol-binding protein I) (CRBP-I) RBP1 CRBP1 Homo sapiens (Human) fatty acid transport [GO:0015908]; lipid homeostasis [GO:0055088]; retinoic acid biosynthetic process [GO:0002138]; vitamin A metabolic process [GO:0006776] cytosol [GO:0005829]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] all-trans-retinol binding [GO:1904768]; fatty acid binding [GO:0005504]; retinal binding [GO:0016918]; retinoid binding [GO:0005501] 0.88375 -0.11972 LQCVQKGEKEGR 0 0 0 0 0 0 0 0 0 9.3773 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P09466 PAEP_HUMAN Glycodelin (GD) (Placental protein 14) (PP14) (Pregnancy-associated endometrial alpha-2 globulin) (PAEG) (PEG) (Progestagen-associated endometrial protein) (Progesterone-associated endometrial protein) (Zona-binding inhibitory factor-1) (ZIF-1) PAEP Homo sapiens (Human) apoptotic process [GO:0006915]; negative regulation of sperm capacitation [GO:1902491]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; regulation of binding of sperm to zona pellucida [GO:2000359] extracellular region [GO:0005576] small molecule binding [GO:0036094] 0.88506 -0.24262 AFRPLPRHLWYLLDLK 0 0 11.421 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P09471 GNAO_HUMAN Guanine nucleotide-binding protein G(o) subunit alpha GNAO1 Homo sapiens (Human) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; dopamine receptor signaling pathway [GO:0007212]; muscle contraction [GO:0006936] heterotrimeric G-protein complex [GO:0005834]; plasma membrane [GO:0005886] corticotropin-releasing hormone receptor 1 binding [GO:0051430]; G protein-coupled serotonin receptor binding [GO:0031821]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; mu-type opioid receptor binding [GO:0031852] 0.88284 -0.088277 LLLLGAGESGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.97174 0 0 0 10.719 0 0 P09493 TPM1_HUMAN Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1) TPM1 C15orf13 TMSA Homo sapiens (Human) actin filament organization [GO:0007015]; cardiac muscle contraction [GO:0060048]; cellular response to reactive oxygen species [GO:0034614]; cytoskeleton organization [GO:0007010]; muscle filament sliding [GO:0030049]; negative regulation of cell migration [GO:0030336]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; positive regulation of ATP-dependent activity [GO:0032781]; positive regulation of cell adhesion [GO:0045785]; positive regulation of heart rate by epinephrine [GO:0003065]; positive regulation of stress fiber assembly [GO:0051496]; regulation of cell shape [GO:0008360]; regulation of heart contraction [GO:0008016]; regulation of muscle contraction [GO:0006937]; ruffle organization [GO:0031529]; sarcomere organization [GO:0045214]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; wound healing [GO:0042060] actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; bleb [GO:0032059]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; muscle thin filament tropomyosin [GO:0005862]; ruffle membrane [GO:0032587]; sarcomere [GO:0030017]; stress fiber [GO:0001725] actin binding [GO:0003779]; actin filament binding [GO:0051015]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307] 0.0058997 2.4125 ATDAEADVASLNRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.58071 0 0 0 0 0 0 0 0 0 9.96939 0 0 P09496 CLCA_HUMAN Clathrin light chain A (Lca) CLTA Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886] clathrin coat [GO:0030118]; clathrin coat of coated pit [GO:0030132]; clathrin coat of trans-Golgi network vesicle [GO:0030130]; clathrin complex [GO:0071439]; clathrin vesicle coat [GO:0030125]; clathrin-coated endocytic vesicle [GO:0045334]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endolysosome membrane [GO:0036020]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic endocytic zone cytoplasmic component [GO:0099631]; presynaptic endocytic zone membrane [GO:0098835]; spindle [GO:0005819]; synaptic vesicle membrane [GO:0030672]; trans-Golgi network membrane [GO:0032588] clathrin heavy chain binding [GO:0032050]; GTPase binding [GO:0051020]; peptide binding [GO:0042277]; protein-containing complex binding [GO:0044877]; structural molecule activity [GO:0005198] 0.9651 -2.7075 LEALDANSR 0 0 0 0 0 0 9.21483 0 0 9.60049 0 9.19815 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P09497 CLCB_HUMAN Clathrin light chain B (Lcb) CLTB Homo sapiens (Human) clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886] ciliary membrane [GO:0060170]; clathrin coat [GO:0030118]; clathrin coat of coated pit [GO:0030132]; clathrin coat of trans-Golgi network vesicle [GO:0030130]; clathrin vesicle coat [GO:0030125]; clathrin-coated endocytic vesicle [GO:0045334]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; postsynaptic endocytic zone cytoplasmic component [GO:0099631]; presynaptic endocytic zone membrane [GO:0098835]; synaptic vesicle membrane [GO:0030672]; trans-Golgi network [GO:0005802] clathrin heavy chain binding [GO:0032050]; peptide binding [GO:0042277]; structural molecule activity [GO:0005198] 0.91526 -0.77739 DLEEWNQRQSEQVEK 0 0 0 0 0 0 0 0 0 0 11.0947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P09525 ANXA4_HUMAN Annexin A4 (35-beta calcimedin) (Annexin IV) (Annexin-4) (Carbohydrate-binding protein p33/p41) (Chromobindin-4) (Endonexin I) (Lipocortin IV) (P32.5) (PP4-X) (Placental anticoagulant protein II) (PAP-II) (Protein II) ANXA4 ANX4 Homo sapiens (Human) epithelial cell differentiation [GO:0030855]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; Notch signaling pathway [GO:0007219]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165] cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; extracellular exosome [GO:0070062]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506] calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phospholipase inhibitor activity [GO:0004859] 0.88198 -0.063234 AEIDMLDIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7228 0 0 0 0 0 0 0 0 0 0 0 0 P09529 INHBB_HUMAN Inhibin beta B chain (Activin beta-B chain) INHBB Homo sapiens (Human) activin receptor signaling pathway [GO:0032924]; apoptotic signaling pathway [GO:0097190]; BMP signaling pathway [GO:0030509]; cell differentiation [GO:0030154]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to cholesterol [GO:0071397]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to leptin stimulus [GO:0044320]; cellular response to starvation [GO:0009267]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; cellular response to thyroid hormone stimulus [GO:0097067]; defense response [GO:0006952]; fat cell differentiation [GO:0045444]; multicellular organism aging [GO:0010259]; negative regulation of follicle-stimulating hormone secretion [GO:0046882]; negative regulation of hepatocyte growth factor production [GO:0032686]; negative regulation of insulin secretion [GO:0046676]; oocyte development [GO:0048599]; ovarian follicle development [GO:0001541]; pituitary gland development [GO:0021983]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of follicle-stimulating hormone secretion [GO:0046881]; positive regulation of ovulation [GO:0060279]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; response to gonadotropin [GO:0034698]; response to insecticide [GO:0017085]; response to wounding [GO:0009611]; seminiferous tubule development [GO:0072520]; SMAD protein signal transduction [GO:0060395]; spermatogenesis [GO:0007283] cell periphery [GO:0071944]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471] cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; host cell surface receptor binding [GO:0046789]; protein homodimerization activity [GO:0042803] 0.87046 0.04139 DVPNMIVEECGCA 0 0 9.77602 0 0 0 10.5248 10.2904 0 11.2973 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P09543 CN37_HUMAN "2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) (CNPase) (EC 3.1.4.37)" CNP Homo sapiens (Human) adult locomotory behavior [GO:0008344]; aging [GO:0007568]; axonogenesis [GO:0007409]; chemical synaptic transmission [GO:0007268]; cyclic nucleotide catabolic process [GO:0009214]; forebrain development [GO:0030900]; microtubule cytoskeleton organization [GO:0000226]; oligodendrocyte differentiation [GO:0048709]; regulation of mitochondrial membrane permeability [GO:0046902]; response to lipopolysaccharide [GO:0032496]; response to toxic substance [GO:0009636]; substantia nigra development [GO:0021762] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; melanosome [GO:0042470]; membrane [GO:0016020]; microtubule [GO:0005874]; microvillus [GO:0005902]; mitochondrial inner membrane [GO:0005743]; mitochondrial outer membrane [GO:0005741]; myelin sheath abaxonal region [GO:0035748]; myelin sheath adaxonal region [GO:0035749]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]; synapse [GO:0045202] "2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [GO:0004113]; cyclic nucleotide binding [GO:0030551]; RNA binding [GO:0003723]" 0.92324 -1.0738 AIFTGYYGK 0 0 0 0 0 0 0 0 0 9.91519 0 0 0 0 8.62669 0 0 11.41 0 0 0 9.64784 0 9.81377 0 0 0 P09544 WNT2_HUMAN Protein Wnt-2 (Int-1-like protein 1) (Int-1-related protein) (IRP) WNT2 INT1L1 IRP Homo sapiens (Human) atrial cardiac muscle tissue morphogenesis [GO:0055009]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904954]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac muscle cell proliferation [GO:0060038]; cell fate commitment [GO:0045165]; cell proliferation in midbrain [GO:0033278]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; epithelial cell proliferation involved in lung morphogenesis [GO:0060502]; iris morphogenesis [GO:0061072]; labyrinthine layer blood vessel development [GO:0060716]; lens development in camera-type eye [GO:0002088]; lung induction [GO:0060492]; mammary gland epithelium development [GO:0061180]; mesenchymal cell proliferation [GO:0010463]; midbrain dopaminergic neuron differentiation [GO:1904948]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neurogenesis [GO:0050769]; positive regulation of transcription by RNA polymerase II [GO:0045944] collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Wnt signalosome [GO:1990909] cytokine activity [GO:0005125]; frizzled binding [GO:0005109]; receptor ligand activity [GO:0048018] 0.96191 -2.5603 ALMNLHNNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.41121 0 P09603 CSF1_HUMAN Macrophage colony-stimulating factor 1 (CSF-1) (M-CSF) (MCSF) (Lanimostim) (Proteoglycan macrophage colony-stimulating factor) (PG-M-CSF) [Cleaved into: Processed macrophage colony-stimulating factor 1; Macrophage colony-stimulating factor 1 43 kDa subunit] CSF1 Homo sapiens (Human) branching involved in mammary gland duct morphogenesis [GO:0060444]; cellular response to parathyroid hormone stimulus [GO:0071374]; developmental process involved in reproduction [GO:0003006]; homeostasis of number of cells within a tissue [GO:0048873]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; macrophage colony-stimulating factor signaling pathway [GO:0038145]; macrophage differentiation [GO:0030225]; macrophage homeostasis [GO:0061519]; mammary duct terminal end bud growth [GO:0060763]; mammary gland fat development [GO:0060611]; microglial cell proliferation [GO:0061518]; monocyte activation [GO:0042117]; monocyte differentiation [GO:0030224]; monocyte homeostasis [GO:0035702]; myeloid leukocyte migration [GO:0097529]; negative regulation of neuron death [GO:1901215]; neutrophil homeostasis [GO:0001780]; odontogenesis [GO:0042476]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; osteoclast proliferation [GO:0002158]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of macrophage colony-stimulating factor signaling pathway [GO:1902228]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of macrophage migration [GO:1905523]; positive regulation of macrophage proliferation [GO:0120041]; positive regulation of microglial cell migration [GO:1904141]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of mononuclear cell proliferation [GO:0032946]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of odontogenesis of dentin-containing tooth [GO:0042488]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of Ras protein signal transduction [GO:0046579]; Ras protein signal transduction [GO:0007265]; regulation of macrophage derived foam cell differentiation [GO:0010743]; regulation of ossification [GO:0030278]; response to ischemia [GO:0002931]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] CSF1-CSF1R complex [GO:1990682]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; nuclear body [GO:0016604]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; macrophage colony-stimulating factor receptor binding [GO:0005157]; protein homodimerization activity [GO:0042803] 0.96337 -2.6548 SCFTKDYEEHDK 0 0 0 10.7473 11.014 0 0 9.13065 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P09622 DLDH_HUMAN "Dihydrolipoyl dehydrogenase, mitochondrial (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein)" DLD GCSL LAD PHE3 Homo sapiens (Human) "acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; branched-chain amino acid catabolic process [GO:0009083]; gastrulation [GO:0007369]; histone succinylation [GO:0106077]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; proteolysis [GO:0006508]; regulation of membrane potential [GO:0042391]; sperm capacitation [GO:0048240]" acetyltransferase complex [GO:1902493]; acrosomal matrix [GO:0043159]; mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrial pyruvate dehydrogenase complex [GO:0005967]; mitochondrion [GO:0005739]; motile cilium [GO:0031514]; nucleus [GO:0005634]; oxoglutarate dehydrogenase complex [GO:0045252]; pyruvate dehydrogenase complex [GO:0045254] dihydrolipoyl dehydrogenase activity [GO:0004148]; flavin adenine dinucleotide binding [GO:0050660] 0.9639 -2.112 EANLAASFGK 0 0 0 0 0 0 0 0 0 0 9.96379 0 0 0 0 0 0 0 0 0 0 0 10.2596 0 0 0 0 P09651 ROA1_HUMAN "Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]" HNRNPA1 HNRPA1 Homo sapiens (Human) "amyloid fibril formation [GO:1990000]; cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; import into nucleus [GO:0051170]; localization [GO:0051179]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of RNA splicing [GO:0043484]; RNA export from nucleus [GO:0006405]" catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular non-membrane-bounded organelle [GO:0043232]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681] DNA binding [GO:0003677]; G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; molecular condensate scaffold activity [GO:0140693]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752] 0.0058824 2.3753 EDSQRPGAHLTVK 9.50948 8.65116 8.91232 0 0 0 9.37071 0 0 12.0402 0 9.83183 0 0 0 0 0 0 9.27594 0 8.90617 0 0 0 0 10.81 10.1677 P09661 RU2A_HUMAN U2 small nuclear ribonucleoprotein A' (U2 snRNP A') SNRPA1 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; spermatogenesis [GO:0007283]; U2-type prespliceosome assembly [GO:1903241]" catalytic step 2 spliceosome [GO:0071013]; nuclear body [GO:0016604]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; small nuclear ribonucleoprotein complex [GO:0030532]; spliceosomal complex [GO:0005681]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005] RNA binding [GO:0003723]; U2 snRNA binding [GO:0030620] 0.95584 -1.5472 ELDLRGYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4504 0 0 0 0 0 0 10.1798 0 0 0 P09693 CD3G_HUMAN T-cell surface glycoprotein CD3 gamma chain (T-cell receptor T3 gamma chain) (CD antigen CD3g) CD3G T3G Homo sapiens (Human) adaptive immune response [GO:0002250]; alpha-beta T cell activation [GO:0046631]; cell surface receptor signaling pathway [GO:0007166]; establishment or maintenance of cell polarity [GO:0007163]; gamma-delta T cell activation [GO:0046629]; positive thymic T cell selection [GO:0045059]; protein transport [GO:0015031]; protein-containing complex assembly [GO:0065003]; regulation of lymphocyte apoptotic process [GO:0070228]; T cell activation [GO:0042110]; T cell receptor signaling pathway [GO:0050852] alpha-beta T cell receptor complex [GO:0042105]; clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; gamma-delta T cell receptor complex [GO:0042106]; plasma membrane [GO:0005886] identical protein binding [GO:0042802]; signaling receptor complex adaptor activity [GO:0030159]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888] 0.47913 0.62505 EDDQYSHLQGNQLRRN 0 0 0 0 0 0 0 0 0 0 11.2629 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P09769 FGR_HUMAN Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr) FGR SRC2 Homo sapiens (Human) bone mineralization [GO:0030282]; cell differentiation [GO:0030154]; defense response to Gram-positive bacterium [GO:0050830]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response-regulating cell surface receptor signaling pathway [GO:0002768]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; myoblast proliferation [GO:0051450]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of natural killer cell activation [GO:0032815]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell migration [GO:0030335]; positive regulation of cytokine production [GO:0001819]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell shape [GO:0008360]; regulation of innate immune response [GO:0045088]; regulation of phagocytosis [GO:0050764]; regulation of protein kinase activity [GO:0045859]; response to virus [GO:0009615]; skeletal system morphogenesis [GO:0048705]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] actin cytoskeleton [GO:0015629]; aggresome [GO:0016235]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; secretory granule lumen [GO:0034774] ATP binding [GO:0005524]; Fc-gamma receptor I complex binding [GO:0034988]; immunoglobulin receptor binding [GO:0034987]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102] 0.93029 -1.2342 LDMGGYYITTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.85318 0 0 P09848 LPH_HUMAN Lactase/phlorizin hydrolase (Lactase/glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Glycosylceramidase (EC 3.2.1.62) (Phlorizin hydrolase)] LCT LPH Homo sapiens (Human) cellobiose catabolic process [GO:2000892]; glycosylceramide catabolic process [GO:0046477]; lactose catabolic process [GO:0005990]; quercetin catabolic process [GO:1901733] external side of apical plasma membrane [GO:0098591]; plasma membrane [GO:0005886] beta-glucosidase activity [GO:0008422]; cellobiose glucosidase activity [GO:0080079]; galactosylceramidase activity [GO:0004336]; glucosylceramidase activity [GO:0004348]; glycosylceramidase activity [GO:0017042]; lactase activity [GO:0000016]; phlorizin hydrolase activity [GO:0140749]; protein homodimerization activity [GO:0042803] 0.91468 -0.81551 FGLHFVNYSDPSLPRIPKASAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1252 0 0 0 0 0 P09874 PARP1_HUMAN "Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (DNA ADP-ribosyltransferase PARP1) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1) (Protein poly-ADP-ribosyltransferase PARP1) (EC 2.4.2.-) [Cleaved into: Poly [ADP-ribose] polymerase 1, processed C-terminus (Poly [ADP-ribose] polymerase 1, 89-kDa form); Poly [ADP-ribose] polymerase 1, processed N-terminus (NT-PARP-1) (Poly [ADP-ribose] polymerase 1, 24-kDa form) (Poly [ADP-ribose] polymerase 1, 28-kDa form)]" PARP1 ADPRT PPOL Homo sapiens (Human) "apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; carbohydrate biosynthetic process [GO:0016051]; cellular response to amyloid-beta [GO:1904646]; cellular response to insulin stimulus [GO:0032869]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; decidualization [GO:0046697]; DNA ADP-ribosylation [GO:0030592]; DNA damage response [GO:0006974]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; innate immune response [GO:0045087]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of adipose tissue development [GO:1904178]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of innate immune response [GO:0045824]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of necroptotic process [GO:0060545]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein localization to chromatin [GO:0071168]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of base-excision repair [GO:1905051]; regulation of catalytic activity [GO:0050790]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of protein localization [GO:0032880]; regulation of SMAD protein complex assembly [GO:0010990]; replication fork reversal [GO:0071932]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]" "chromatin [GO:0000785]; chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear replication fork [GO:0043596]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription regulator complex [GO:0005667]" chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; enzyme activator activity [GO:0008047]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+- protein-aspartate ADP-ribosyltransferase activity [GO:0140806]; NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity [GO:0140822]; NAD+-histone H2BS6 serine ADP-ribosyltransferase activity [GO:0140816]; NAD+-histone H3S10 serine ADP-ribosyltransferase activity [GO:0140817]; NAD+-protein ADP-ribosyltransferase activity [GO:1990404]; NAD+-protein-glutamate ADP-ribosyltransferase activity [GO:0140807]; NAD+-protein-histidine ADP-ribosyltransferase activity [GO:0140815]; NAD+-protein-serine ADP-ribosyltransferase activity [GO:0140805]; NAD+-protein-tyrosine ADP-ribosyltransferase activity [GO:0140808]; nuclear estrogen receptor binding [GO:0030331]; nucleosome binding [GO:0031491]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; zinc ion binding [GO:0008270] 0.7571 0.30504 AEPVEVVAPR 0 9.37955 0 0 0 0 0 9.69399 0 0 9.78996 0 0 10.3105 0 0 10.7005 10.5229 9.00405 0 0 0 0 0 9.17759 12.1452 10.7442 P09884 DPOLA_HUMAN DNA polymerase alpha catalytic subunit (EC 2.7.7.7) (DNA polymerase alpha catalytic subunit p180) POLA1 POLA Homo sapiens (Human) "DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; DNA replication, synthesis of RNA primer [GO:0006269]; DNA strand elongation involved in DNA replication [GO:0006271]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair via nonhomologous end joining [GO:0006303]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; mitotic DNA replication initiation [GO:1902975]; regulation of type I interferon production [GO:0032479]" alpha DNA polymerase:primase complex [GO:0005658]; cytosol [GO:0005829]; nuclear envelope [GO:0005635]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA replication origin binding [GO:0003688]; DNA-directed DNA polymerase activity [GO:0003887]; nucleotide binding [GO:0000166]; protein kinase binding [GO:0019901]; single-stranded DNA binding [GO:0003697]; zinc ion binding [GO:0008270] 0.88277 -0.093654 ETGTPISMKDVYEEFDEKIATK 0 0 0 0 0 9.30015 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P09913 IFIT2_HUMAN Interferon-induced protein with tetratricopeptide repeats 2 (IFIT-2) (ISG-54 K) (Interferon-induced 54 kDa protein) (IFI-54K) (P54) IFIT2 CIG-42 G10P2 IFI54 ISG54 Homo sapiens (Human) antiviral innate immune response [GO:0140374]; apoptotic mitochondrial changes [GO:0008637]; defense response to virus [GO:0051607]; negative regulation of protein binding [GO:0032091]; positive regulation of apoptotic process [GO:0043065]; response to virus [GO:0009615] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783] RNA binding [GO:0003723] 0.94375 -1.337 CGGNQNERAKVCFEK 0 0 0 0 0 0 0 0 0 0 0 0 10.2863 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P09960 LKHA4_HUMAN Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase) (Tripeptide aminopeptidase LTA4H) (EC 3.4.11.4) LTA4H LTA4 Homo sapiens (Human) leukotriene biosynthetic process [GO:0019370]; lipid metabolic process [GO:0006629]; peptide catabolic process [GO:0043171]; protein metabolic process [GO:0019538]; proteolysis [GO:0006508]; response to peptide hormone [GO:0043434]; response to zinc ion [GO:0010043]; type I pneumocyte differentiation [GO:0060509] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724] aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; tripeptide aminopeptidase activity [GO:0045148]; zinc ion binding [GO:0008270] 0.0060976 2.5842 DLAAFDK 0 0 0 0 0 0 0 0 0 0 0 0 9.74298 0 0 10.18 10.2688 0 0 0 0 0 0 0 10.871 11.1049 10.7178 P09972 ALDOC_HUMAN Fructose-bisphosphate aldolase C (EC 4.1.2.13) (Brain-type aldolase) ALDOC ALDC Homo sapiens (Human) "epithelial cell differentiation [GO:0030855]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]" cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724] cytoskeletal protein binding [GO:0008092]; fructose-bisphosphate aldolase activity [GO:0004332] 0 46.905 AEVNGLAAQGK 11.3893 11.4934 11.3307 0 0 0 11.6526 11.7413 11.6388 12.1565 12.0449 12.1206 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0C025 NUD17_HUMAN Nucleoside diphosphate-linked moiety X motif 17 (Nudix motif 17) (EC 3.6.1.-) NUDT17 Homo sapiens (Human) NAD catabolic process [GO:0019677]; NADH metabolic process [GO:0006734]; NADP catabolic process [GO:0006742] peroxisome [GO:0005777] metal ion binding [GO:0046872]; NADH pyrophosphatase activity [GO:0035529] 0.95343 -1.4964 VSTGTKFALK 0 0 0 0 10.3535 0 0 0 0 0 0 0 0 0 0 0 11.8009 0 0 0 0 0 0 0 0 0 0 P0C091 FREM3_HUMAN FRAS1-related extracellular matrix protein 3 FREM3 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell communication [GO:0007154] basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; membrane [GO:0016020] metal ion binding [GO:0046872] 0.96934 -3.4684 ISYVHTSNDEKK 9.58308 0 0 0 0 0 10.0228 0 0 10.4947 0 10.202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0C0E4 RB40L_HUMAN Ras-related protein Rab-40A-like (Ras-like GTPase) RAB40AL RLGP Homo sapiens (Human) intracellular signal transduction [GO:0035556]; protein localization to plasma membrane [GO:0072659]; protein ubiquitination [GO:0016567] cytoplasm [GO:0005737]; endosome [GO:0005768]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; synaptic vesicle [GO:0008021] GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.85586 0.10406 IVCPPQSPPKNCTR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3324 0 0 10.0531 0 0 0 0 0 0 0 0 0 0 P0C0L4 CO4A_HUMAN Complement C4-A (Acidic complement C4) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2) [Cleaved into: Complement C4 beta chain; Complement C4-A alpha chain; C4a anaphylatoxin; C4b-A; C4d-A; Complement C4 gamma chain] C4A CO4 CPAMD2 Homo sapiens (Human) "complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of immune response [GO:0050778]; positive regulation of opsonization [GO:1903028]" axon [GO:0030424]; blood microparticle [GO:0072562]; classical-complement-pathway C3/C5 convertase complex [GO:0005601]; dendrite [GO:0030425]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; synapse [GO:0045202] complement component C1q complex binding [GO:0001849]; endopeptidase inhibitor activity [GO:0004866] 0.96387 -2.6466 FACYYPRVEYGFQVK 8.93981 9.12197 0 0 0 0 0 0 0 0 9.93489 0 0 8.98214 8.89215 0 0 0 0 0 0 0 0 0 0 0 0 P0C1S8 WEE2_HUMAN Wee1-like protein kinase 2 (EC 2.7.10.2) (Wee1-like protein kinase 1B) (Wee1B kinase) WEE2 WEE1B Homo sapiens (Human) female meiotic nuclear division [GO:0007143]; female pronucleus assembly [GO:0035038]; mitotic cell cycle [GO:0000278]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of oocyte maturation [GO:1900194]; positive regulation of phosphorylation [GO:0042327]; protein phosphorylation [GO:0006468]; regulation of fertilization [GO:0080154]; regulation of meiosis I [GO:0060631] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein tyrosine kinase activity [GO:0004713] 0.94921 -1.3751 ETNMASRYEK 0 0 0 0 0 0 0 0 0 9.42162 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0C2W1 FBSP1_HUMAN F-box/SPRY domain-containing protein 1 (F-box only protein 45) (hFbxo45) FBXO45 FBX45 Homo sapiens (Human) anterior commissure morphogenesis [GO:0021960]; cerebral cortex radially oriented cell migration [GO:0021799]; cerebral cortex tangential migration [GO:0021800]; corticospinal tract morphogenesis [GO:0021957]; DNA damage response [GO:0006974]; neuron migration [GO:0001764]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; regulation of synaptic vesicle exocytosis [GO:2000300]; synapse assembly involved in innervation [GO:0060386]; ubiquitin-dependent protein catabolic process [GO:0006511] cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; glutamatergic synapse [GO:0098978]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynaptic cytosol [GO:0099523]; presynaptic membrane [GO:0042734]; SCF ubiquitin ligase complex [GO:0019005]; synapse [GO:0045202] ubiquitin ligase-substrate adaptor activity [GO:1990756] 0.88342 -0.26292 SLCARSLAEEALR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5909 0 P0C2Y1 NBPF7_HUMAN Putative neuroblastoma breakpoint family member 7 NBPF7P NBPF7 Homo sapiens (Human) cytoplasm [GO:0005737] 0.94847 -1.3641 EVLQDSPEER 0 9.45724 0 0 0 0 12.0626 0 0 10.9305 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0C604 OR4A8_HUMAN Olfactory receptor 4A8 (Olfactory receptor OR11-110) OR4A8 OR4A8P Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.8776 -0.0043149 YVATCKPLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0242 0 P0C629 O10J4_HUMAN Olfactory receptor 10J4 OR10J4 OR10J4P Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of smell [GO:0050911] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; odorant binding [GO:0005549]; olfactory receptor activity [GO:0004984] 0.95511 -1.5543 EVKDALLR 0 0 0 0 0 0 0 0 0 0 0 0 11.2665 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0C645 OR4E1_HUMAN Olfactory receptor 4E1 (Olfactory receptor OR14-43) OR4E1 OR4E1P Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of smell [GO:0050911] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; odorant binding [GO:0005549]; olfactory receptor activity [GO:0004984] 0.8838 -0.25569 NEEMKSALNK 0 0 0 0 0 0 0 0 0 0 9.06501 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0C672 TSN19_HUMAN Tetraspanin-19 (Tspan-19) TSPAN19 Homo sapiens (Human) membrane [GO:0016020] 0.32474 0.78307 KWFCDEPLNATYLEGCENK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.13712 0 0 0 0 0 0 0 0 0 0 0 0 P0C6A0 ZGLP1_HUMAN GATA-type zinc finger protein 1 (GATA-like protein 1) (GLP-1) ZGLP1 GLP1 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; oocyte development [GO:0048599]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283] nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]" 0.96719 -3.7044 GRRLQPPGTPSAPPQR 0 0 0 0 0 0 0 13.8326 0 0 0 0 0 9.08582 0 0 0 0 0 0 0 0 0 0 0 0 0 P0C6C1 AN34C_HUMAN Ankyrin repeat domain-containing protein 34C ANKRD34C Homo sapiens (Human) piRNA processing [GO:0034587] pi-body [GO:0071546] 0.40479 0.7023 ALGLDSPLTEK 0 10.6059 0 0 0 0 0 0 0 0 0 10.4502 0 0 0 0 0 0 0 0 0 0 10.4801 9.34687 0 0 0 P0C7M8 CLC2L_HUMAN C-type lectin domain family 2 member L CLEC2L Homo sapiens (Human) membrane [GO:0016020] carbohydrate binding [GO:0030246] 0.9215 -1.1095 CYFFSEEPR 0 0 0 0 0 0 0 0 0 0 8.48981 0 0 0 10.1279 0 0 0 0 0 0 9.6755 0 0 0 0 0 P0C7N8 OR9G9_HUMAN Olfactory receptor 9G9 OR9G9 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.95016 -1.4036 ISSSQGRLK 0 11.2237 0 0 0 0 0 0 0 0 0 0 0 0 11.7977 0 0 0 0 0 0 0 0 0 0 0 0 P0C7P0 CISD3_HUMAN "CDGSH iron-sulfur domain-containing protein 3, mitochondrial (MitoNEET-related protein 2) (Miner2) (Mitochondrial inner NEET protein) (MiNT)" CISD3 Homo sapiens (Human) protein maturation by [2Fe-2S] cluster transfer [GO:0106034] mitochondrion [GO:0005739] "2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]" 0.92153 -1.1371 AEVGSPL 0 0 0 0 0 0 0 0 0 13.8509 0 0 0 0 7.97963 0 0 0 0 0 0 0 0 8.96552 0 0 0 P0C7P3 SLN14_HUMAN Protein SLFN14 [Cleaved into: C-terminally truncated SLFN14 endoribonuclease (EC 3.1.-.-) (Schlafen family member 14)] SLFN14 Homo sapiens (Human) "cellular response to magnesium ion [GO:0071286]; cellular response to manganese ion [GO:0071287]; mRNA catabolic process [GO:0006402]; platelet maturation [GO:0036345]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; rRNA catabolic process [GO:0016075]" cytoplasm [GO:0005737]; nucleus [GO:0005634] ATP binding [GO:0005524]; ribosome binding [GO:0043022]; RNA endonuclease activity [GO:0004521] 0.96976 -3.0899 DLFHCKPK 0 0 0 0 0 0 9.14091 0 9.26533 0 9.56565 8.28327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0C7Q2 ARMS2_HUMAN Age-related maculopathy susceptibility protein 2 ARMS2 Homo sapiens (Human) retina homeostasis [GO:0001895] mitochondrion [GO:0005739]; photoreceptor inner segment [GO:0001917] 0.91268 -0.74914 ESVLDPGVGGEGASDK 0 0 0 0 0 0 0 0 0 0 0 9.73234 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0C7T5 ATX1L_HUMAN Ataxin-1-like (Brother of ataxin-1) (Brother of ATXN1) ATXN1L BOAT BOAT1 Homo sapiens (Human) anatomical structure development [GO:0048856]; brain development [GO:0007420]; extracellular matrix organization [GO:0030198]; learning [GO:0007612]; lung alveolus development [GO:0048286]; memory [GO:0007613]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; regulation of DNA-templated transcription [GO:0006355]; social behavior [GO:0035176]; transcription by RNA polymerase II [GO:0006366] dendrite [GO:0030425]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; RNA binding [GO:0003723] 0.83594 0.19447 SQECLPPK 8.84797 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0C7U0 ELFN1_HUMAN Protein ELFN1 (Extracellular leucine-rich repeat and fibronectin type-III domain-containing protein 1) (Protein phosphatase 1 regulatory subunit 28) ELFN1 PPP1R28 Homo sapiens (Human) synapse organization [GO:0050808] dendrite [GO:0030425]; excitatory synapse [GO:0060076]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; membrane [GO:0016020] protein phosphatase inhibitor activity [GO:0004864] 0.73784 0.32561 LVESADTPK 0 0 0 0 0 7.93852 0 0 0 0 9.27041 0 0 0 0 0 0 8.95329 0 0 0 0 0 0 0 0 0 P0C7U9 FA87A_HUMAN Protein FAM87A FAM87A Homo sapiens (Human) membrane [GO:0016020] 0.59043 0.46163 LFFPEGGALKEHFSSMDSFQLR 0 0 0 0 0 10.8938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.74504 0 0 0 0 P0C7V7 SC11B_HUMAN Putative signal peptidase complex catalytic subunit SEC11B (EC 3.4.21.89) (SEC11 homolog B) (SEC11-like protein 2) SEC11B SEC11L2 SPCS4B Homo sapiens (Human) signal peptide processing [GO:0006465] signal peptidase complex [GO:0005787] peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252] 0.89099 -0.50324 KIPIVHRVLK 9.26615 0 9.11964 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0C7W6 CC172_HUMAN Coiled-coil domain-containing protein 172 CCDC172 C10orf96 Homo sapiens (Human) cytoplasm [GO:0005737]; sperm midpiece [GO:0097225] 0.4356 0.65517 IEISDLENQANMLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.81192 0 0 0 0 0 0 0 0 0 0 0 P0C7X4 FHL19_HUMAN Putative ferritin heavy polypeptide-like 19 (Ferritin heavy polypeptide 1 pseudogene 19) FTH1P19 FTHL19 Homo sapiens (Human) intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826] cytoplasm [GO:0005737] ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198] 0.4043 0.69913 AFYFDQDDAALEHFDRYFLR 0 0 0 0 0 0 0 0 0 0 10.1611 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0C860 MS3L2_HUMAN Putative male-specific lethal-3 protein-like 2 (MSL3-like 2) (Male-specific lethal-3 homolog 2) (Male-specific lethal-3 homolog pseudogene 1) MSL3P1 MSL3L2 Homo sapiens (Human) chromatin organization [GO:0006325]; histone deacetylation [GO:0016575]; histone H2A acetylation [GO:0043968]; histone H4-K16 acetylation [GO:0043984]; regulation of DNA-templated transcription [GO:0006355] MSL complex [GO:0072487]; NuA4 histone acetyltransferase complex [GO:0035267]; nucleus [GO:0005634] 0.87962 0.017394 EMVDGLR 0 0 0 0 0 0 0 0 0 9.07385 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0C862 C1T9A_HUMAN Complement C1q and tumor necrosis factor-related protein 9A (Complement C1q and tumor necrosis factor-related protein 9) C1QTNF9 C1QTNF9A UNQ6503/PRO21380 Homo sapiens (Human) collagen trimer [GO:0005581]; extracellular region [GO:0005576] hormone activity [GO:0005179]; identical protein binding [GO:0042802] 0.92765 -1.2007 GIRGWKGDR 8.90412 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1495 0 0 0 0 0 0 0 0 P0C870 JMJD7_HUMAN Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 (EC 1.14.11.63) (EC 3.4.-.-) (JmjC domain-containing protein 7) (Jumonji domain-containing protein 7) (L-lysine (3S)-hydroxylase JMJD7) JMJD7 Homo sapiens (Human) protein hydroxylation [GO:0018126]; proteolysis [GO:0006508] cytoplasm [GO:0005737]; nucleus [GO:0005634] 2-oxoglutarate-dependent dioxygenase activity [GO:0016706]; aminopeptidase activity [GO:0004177]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; methylated histone binding [GO:0035064]; monooxygenase activity [GO:0004497]; peptidyl-lysine 3-dioxygenase activity [GO:0106155] 0.76509 0.28391 NALQHWPALQK 0 0 0 0 0 0 0 0 0 16.8727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0C875 F228B_HUMAN Protein FAM228B FAM228B Homo sapiens (Human) 0.79681 0.24317 TLLQCETGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.68105 0 0 0 0 0 0 0 0 0 0 P0C879 YJ018_HUMAN Putative uncharacterized protein FLJ43185 Homo sapiens (Human) 0.96764 -3.7084 SASGRLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.86143 0 0 P0C881 R10B1_HUMAN Radial spoke head 10 homolog B RSPH10B Homo sapiens (Human) cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856] 0.9219 -1.0988 HGMGRLTFK 9.02981 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2574 P0CAP1 MYZAP_HUMAN Myocardial zonula adherens protein (GRINL1A upstream protein) (Gup) MYZAP MYOZAP Homo sapiens (Human) intracellular signal transduction [GO:0035556]; maintenance of ER location [GO:0051685] "anchoring junction [GO:0070161]; cortical actin cytoskeleton [GO:0030864]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; I band [GO:0031674]; nuclear envelope [GO:0005635]; RNA polymerase II, holoenzyme [GO:0016591]; Z disc [GO:0030018]" 0.9146 -0.81374 LYSQYEEKLQEEQR 0 10.144 0 0 0 0 10.2379 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0CAP2 GRL1A_HUMAN DNA-directed RNA polymerase II subunit GRINL1A (DNA-directed RNA polymerase II subunit M) (Glutamate receptor-like protein 1A) POLR2M GRINL1A Homo sapiens (Human) intracellular signal transduction [GO:0035556]; maintenance of ER location [GO:0051685] "I band [GO:0031674]; neuronal cell body [GO:0043025]; nuclear envelope [GO:0005635]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase II, holoenzyme [GO:0016591]; transcription preinitiation complex [GO:0097550]" 0.88528 -0.33717 GPASSNR 0 0 0 0 0 0 0 0 0 0 10.8525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0CB33 ZN735_HUMAN Putative zinc finger protein 735 (Zinc finger protein 735 pseudogene) ZNF735 ZNF735P Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96307 -2.0901 IFQTHKCVKVFSK 10.351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.88576 0 0 P0CB38 PAB4L_HUMAN Polyadenylate-binding protein 4-like (PABP-4-like) (Poly(A)-binding protein 4-like) PABPC4L Homo sapiens (Human) cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266] 0.92308 -1.0762 ALDTMNFDIIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8116 0 0 0 9.51909 0 0 0 0 0 0 0 0 P0CB47 UBFL1_HUMAN Upstream-binding factor 1-like protein 1 UBTFL1 C11orf27 Homo sapiens (Human) blastocyst growth [GO:0001832]; embryo implantation [GO:0007566]; positive regulation of transcription by RNA polymerase I [GO:0045943]; transcription by RNA polymerase I [GO:0006360] cytoplasm [GO:0005737]; nucleus [GO:0005634] RNA polymerase I core promoter sequence-specific DNA binding [GO:0001164]; RNA polymerase I general transcription initiation factor activity [GO:0001181] 0.96712 -2.8316 RPLTAYNRFFK 0 0 0 0 9.36772 0 0 0 0 0 0 0 0 9.70077 0 0 0 0 0 0 9.64035 0 0 0 0 0 0 P0CB48 UBFL6_HUMAN Putative upstream-binding factor 1-like protein 6 UBTFL6 Homo sapiens (Human) positive regulation of transcription by RNA polymerase I [GO:0045943]; transcription by RNA polymerase I [GO:0006360] nucleus [GO:0005634] RNA polymerase I core promoter sequence-specific DNA binding [GO:0001164]; RNA polymerase I general transcription initiation factor activity [GO:0001181] 0.95958 -1.8236 DIKVALPR 0 0 0 0 0 10.0038 0 0 0 0 0 0 8.80932 8.99597 0 0 0 0 0 0 0 0 0 0 0 0 0 P0CG00 ZSA5D_HUMAN Putative zinc finger and SCAN domain-containing protein 5D (Zinc finger and SCAN domain-containing protein 5D pseudogene) ZSCAN5DP ZSCAN5D Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.90786 -0.73641 LIHSGEKPYKCPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.58793 0 0 0 P0CG08 GPHRB_HUMAN Golgi pH regulator B (Protein GPR89B) GPR89B GPHRB GPR89C HSPC201 Homo sapiens (Human) intracellular pH reduction [GO:0051452]; protein transport [GO:0015031]; regulation of monoatomic ion transmembrane transport [GO:0034765]; T cell differentiation [GO:0030217] Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139] voltage-gated monoatomic anion channel activity [GO:0008308] 0.77688 0.26385 NVTDTDILALER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9 10.1094 0 P0CG12 DERPC_HUMAN Decreased expression in renal and prostate cancer protein DERPC Homo sapiens (Human) extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654] 0.66709 0.39409 MNGPAGK 0 0 9.21871 0 0 0 0 0 0 0 8.60859 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0CG20 PRR35_HUMAN Proline-rich protein 35 (Uncharacterized protein RJD1) PRR35 C16orf11 Homo sapiens (Human) 0.86409 0.086377 AAQSDPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.41557 0 0 0 0 9.63996 0 0 0 0 P0CG22 DR4L1_HUMAN Putative dehydrogenase/reductase SDR family member 4-like 1 (EC 1.1.-.-) (Short chain dehydrogenase/reductase family 25C member 4) (Protein SDR25C4) DHRS4L1 SDR25C4 Homo sapiens (Human) retinal metabolic process [GO:0042574] peroxisome [GO:0005777] carbonyl reductase (NADPH) activity [GO:0004090] 0.80375 0.23884 LVATAMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.9616 0 0 0 0 0 0 0 0 0 P0CG24 ZN883_HUMAN Zinc finger protein 883 ZNF883 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.85005 0.10936 TFSRSTHLIEHQGIHSEEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6107 0 P0CG37 CFC1_HUMAN Cryptic protein (Cryptic family protein 1) CFC1 Homo sapiens (Human) anatomical structure development [GO:0048856]; determination of left/right symmetry [GO:0007368]; gastrulation [GO:0007369]; nodal signaling pathway [GO:0038092] cell surface [GO:0009986]; extracellular region [GO:0005576]; plasma membrane [GO:0005886] nodal binding [GO:0038100]; signaling receptor binding [GO:0005102] 0.95576 -1.5485 HNGGREEVTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.48111 0 0 0 0 P0CG43 F157C_HUMAN Putative protein FAM157C FAM157C Homo sapiens (Human) 0.95905 -1.9159 AFRFSASPGCGRPSSNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.77526 9.32152 0 0 0 0 0 0 0 P0CI26 TR49C_HUMAN Tripartite motif-containing protein 49C (Tripartite motif-containing protein 49-like protein 2) TRIM49C TRIM49L2 Homo sapiens (Human) innate immune response [GO:0045087]; protein ubiquitination [GO:0016567]; regulation of gene expression [GO:0010468] cytoplasm [GO:0005737] ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.88188 -0.30197 EIFHRLHLSK 12.0782 0 0 0 0 0 11.3432 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0CJ78 ZN865_HUMAN Zinc finger protein 865 ZNF865 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.88396 -0.1082 YLMERRFPCGVCQK 0 0 0 0 0 0 0 0 0 10.0415 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0CJ92 GOG8H_HUMAN Golgin subfamily A member 8H GOLGA8H Homo sapiens (Human) Golgi organization [GO:0007030] cis-Golgi network [GO:0005801]; Golgi cis cisterna [GO:0000137]; Golgi cisterna membrane [GO:0032580] 0.96938 -3.5617 ANQLSSR 0 0 0 0 0 0 0 0 0 9.89228 0 0 0 0 0 0 0 0 0 0 0 0 0 9.6851 0 0 0 P0CK96 S352B_HUMAN Solute carrier family 35 member E2B SLC35E2B KIAA0447 Homo sapiens (Human) blastocyst hatching [GO:0001835] Golgi apparatus [GO:0005794]; membrane [GO:0016020] antiporter activity [GO:0015297] 0.95616 -1.5417 LLSGDKYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5241 0 0 P0CK97 S35E2_HUMAN Solute carrier family 35 member E2A SLC35E2A SLC35E2 Homo sapiens (Human) Golgi apparatus [GO:0005794]; membrane [GO:0016020] antiporter activity [GO:0015297] 0.64393 0.39623 GAAASDR 0 8.97212 0 0 0 0 0 0 0 0 0 0 0 0 0 9.5579 0 8.77027 0 0 0 0 0 0 9.36418 0 0 P0CL83 ST3L1_HUMAN Putative STAG3-like protein 1 (Stromal antigen 3-like protein 1) STAG3L1 Homo sapiens (Human) nucleus [GO:0005634] 0.91628 -0.84759 IFSMLRK 0 0 0 0 8.39142 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0CW18 PRS56_HUMAN Serine protease 56 (EC 3.4.21.-) PRSS56 Homo sapiens (Human) blood coagulation [GO:0007596]; camera-type eye development [GO:0043010]; positive regulation of leukocyte chemotaxis [GO:0002690]; proteolysis [GO:0006508] endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615] serine-type endopeptidase activity [GO:0004252] 0.81248 0.22237 GHHPLNPQVPPAR 0 0 0 0 9.20738 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0CW20 LIMS4_HUMAN LIM and senescent cell antigen-like-containing domain protein 4 (LIM and senescent cell antigen-like-containing domain protein 3-like) LIMS4 LIMS3L Homo sapiens (Human) cellular anatomical entity [GO:0110165] metal ion binding [GO:0046872] 0.959 -1.7161 HSDVKVYK 0 0 9.28128 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0CW24 PNM6A_HUMAN Paraneoplastic antigen-like protein 6A PNMA6A PNMA6C Homo sapiens (Human) 0.96737 -3.7084 ASADRVR 9.13886 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0CW27 CC166_HUMAN Coiled-coil domain-containing protein 166 CCDC166 Homo sapiens (Human) 0.8888 -0.41403 LYASYVSARAQR 0 0 0 0 0 0 0 0 0 10.9875 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0DI83 NARR_HUMAN "Ras-related protein Rab-34, isoform NARR (Nine amino-acid residue-repeats)" RAB34 NARR Homo sapiens (Human) nucleolus [GO:0005730] 0.96738 -2.3475 LPGAPDR 12.0951 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.56573 10.5724 P0DJD0 RGPD1_HUMAN RANBP2-like and GRIP domain-containing protein 1 (Ran-binding protein 2-like 6) (RanBP2-like 6) (RanBP2L6) RGPD1 RANBP2L6 RGP1 Homo sapiens (Human) NLS-bearing protein import into nucleus [GO:0006607] cytoplasm [GO:0005737]; nuclear pore [GO:0005643] 0.96901 -4.2122 AVPGNSAELR 0 0 0 0 0 0 0 17.0795 0 0 0 0 0 9.85649 0 10.9519 0 0 9.37173 0 9.9062 0 0 10.0204 0 0 9.24539 P0DJD4 RBY1C_HUMAN "RNA-binding motif protein, Y chromosome, family 1 member C" RBMY1C Homo sapiens (Human) "mRNA processing [GO:0006397]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]" nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spliceosomal complex [GO:0005681] identical protein binding [GO:0042802]; RNA binding [GO:0003723] 0.88248 -0.067684 DYGHSSWDEHSSR 0 0 0 0 0 0 0 0 0 0 8.88631 9.06072 0 9.31728 0 0 0 0 10.3862 0 0 0 0 11.0546 0 0 11.4474 P0DJG4 THEGL_HUMAN Testicular haploid expressed gene protein-like (Theg spermatid-like protein) THEGL Homo sapiens (Human) 0.88472 -0.1288 TIALAKSKSVHQDYLPDR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.83211 0 0 0 0 0 0 0 0 0 0 0 0 0 P0DJH9 RD3L_HUMAN Protein RD3-like (Retinal degeneration protein 3-like) RD3L Homo sapiens (Human) 0.47094 0.62828 LIQEIENEQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2787 10.0084 0 0 0 P0DKB5 TPBGL_HUMAN Trophoblast glycoprotein-like TPBGL Homo sapiens (Human) negative regulation of canonical Wnt signaling pathway [GO:0090090] plasma membrane [GO:0005886] 0.050209 1.4138 AGQPGLQGLLLVAAALSQPAAPCPFQCYCFGGPK 0 0 0 0 0 0 0 0 8.89942 0 0 0 0 0 0 0 9.77707 0 0 0 0 0 0 0 0 0 0 P0DKB6 MPC1L_HUMAN Mitochondrial pyruvate carrier 1-like protein MPC1L Homo sapiens (Human) mitochondrial pyruvate transmembrane transport [GO:0006850] mitochondrial inner membrane [GO:0005743] pyruvate transmembrane transporter activity [GO:0050833] 0.88531 -0.33742 DNFQSKEFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.88509 0 0 0 P0DKX0 ZN728_HUMAN Zinc finger protein 728 ZNF728 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96877 -3.8862 AFSWPSSLTEHK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4028 0 0 0 0 0 0 0 0 0 0 11.4861 9.86118 0 P0DM35 M1BL1_HUMAN Metallothionein 1H-like protein 1 MT1HL1 Homo sapiens (Human) cellular response to copper ion [GO:0071280] metal ion binding [GO:0046872] 0.95931 -1.8276 CKCTSCKK 0 0 9.69704 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0DMC3 ELA_HUMAN Apelin receptor early endogenous ligand (Protein Elabela) (ELA) (Protein Toddler) APELA ELA TDL Homo sapiens (Human) adult heart development [GO:0007512]; angiogenesis [GO:0001525]; apelin receptor signaling pathway [GO:0060183]; cell migration involved in mesendoderm migration [GO:0090134]; coronary vasculature development [GO:0060976]; embryonic heart tube development [GO:0035050]; endoderm development [GO:0007492]; heart development [GO:0007507]; mesendoderm migration [GO:0090133]; mesoderm migration involved in gastrulation [GO:0007509]; placenta blood vessel development [GO:0060674]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of heart contraction [GO:0045823]; positive regulation of trophoblast cell migration [GO:1901165]; vasculogenesis [GO:0001570] extracellular region [GO:0005576]; extracellular space [GO:0005615] apelin receptor binding [GO:0031704]; hormone activity [GO:0005179] 0.84736 0.15414 CMPLHSR 8.88493 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0DME0 SETLP_HUMAN Protein SETSIP (SET pseudogene protein 18) (SET similar protein) (Similar to SET translocation protein) SETSIP SETP18 Homo sapiens (Human) endothelial cell differentiation [GO:0045446]; nucleosome assembly [GO:0006334]; positive regulation of transcription by RNA polymerase II [GO:0045944] chromatin [GO:0000785]; cytoplasm [GO:0005737]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; histone binding [GO:0042393] 0.87188 0.050708 EFHLNESGDPSSK 0 0 0 0 0 0 0 0 0 0 0 0 10.7347 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0DMQ9 CH089_HUMAN Putative uncharacterized protein C8orf89 C8orf89 Homo sapiens (Human) 0.19659 0.92681 ETCSVAPLWEK 13.3389 0 14.4062 10.4676 11.1362 10.863 14.009 12.7432 12.7638 0 12.4253 12.3439 0 0 0 12.7691 12.149 0 0 0 0 0 0 0 0 0 0 P0DMU2 OR83P_HUMAN Putative olfactory receptor 8G3 pseudogene (Olfactory receptor OR11-297) OR8G3P Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; sensory perception of smell [GO:0007608] membrane [GO:0016020]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; odorant binding [GO:0005549]; olfactory receptor activity [GO:0004984] 0.76488 0.28529 MLVNFATEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6998 0 0 0 0 0 0 0 0 0 P0DMU3 F231L_HUMAN FAM231A/C-like protein LOC102723383 Homo sapiens (Human) 0.95323 -1.501 VGQERWLIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.0662 0 0 0 0 0 0 0 0 P0DMV9 HS71B_HUMAN Heat shock 70 kDa protein 1B (Heat shock 70 kDa protein 2) (HSP70-2) (HSP70.2) HSPA1B HSP72 Homo sapiens (Human) ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to steroid hormone stimulus [GO:0071383]; chaperone cofactor-dependent protein refolding [GO:0051085]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of mitotic spindle assembly [GO:1901673]; regulation of protein ubiquitination [GO:0031396] aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein disaggregase activity [GO:0140545]; ATP-dependent protein folding chaperone [GO:0140662]; C3HC4-type RING finger domain binding [GO:0055131]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618] 0 323.31 AFYPEEISSMVLTK 16.6306 16.6219 16.5361 10.7016 11.2825 11.4504 13.1791 13.0737 13.1772 17.1936 16.7179 17.0607 13.9535 13.2796 13.705 13.6087 13.3799 12.9212 14.9993 14.8628 14.9696 12.4688 12.3048 12.5607 13.8563 14.325 13.6415 P0DMW4 SIL2A_HUMAN Small integral membrane protein 10-like protein 2A SMIM10L2A LINC00086 NCRNA00086 Homo sapiens (Human) 0.87187 0.029987 TLLTFFDLAWR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.74305 0 0 0 0 0 0 0 0 0 P0DN81 O13C7_HUMAN Olfactory receptor 13C7 OR13C7 OR13C7P Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of smell [GO:0050911] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.96931 -3.3109 DLIFQKCFA 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.77111 P0DO97 CC192_HUMAN Coiled-coil domain-containing protein 192 CCDC192 LINC01183 Homo sapiens (Human) 0.84685 0.15396 LEAVDHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.83679 0 0 0 0 0 0 0 P0DOX4 IGE_HUMAN Immunoglobulin epsilon heavy chain (Immunoglobulin epsilon heavy chain ND) Homo sapiens (Human) adaptive immune response [GO:0002250] extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886] 0.81263 0.22391 VAHTPSSTVDNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.97011 0 0 0 0 P0DOX6 IGM_HUMAN Immunoglobulin mu heavy chain (Immunoglobulin mu heavy chain OU) Homo sapiens (Human) adaptive immune response [GO:0002250] extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886] 0.95264 -1.474 LSISKNDSK 9.75342 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0DP25 CALM3_HUMAN Calmodulin-3 CALM3 CALML2 CAM3 CAMC CAMIII Homo sapiens (Human) detection of calcium ion [GO:0005513]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G protein-coupled receptor signaling pathway [GO:0007186]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of calcium ion export across plasma membrane [GO:1905913]; negative regulation of high voltage-gated calcium channel activity [GO:1901842]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cardiac muscle cell action potential [GO:0098901]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]; response to calcium ion [GO:0051592]; response to corticosterone [GO:0051412]; substantia nigra development [GO:0021762] calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; growth cone [GO:0030426]; mitochondrial membrane [GO:0031966]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; sperm midpiece [GO:0097225]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; synaptic vesicle membrane [GO:0030672]; vesicle [GO:0031982]; voltage-gated potassium channel complex [GO:0008076] adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; transmembrane transporter binding [GO:0044325]; type 3 metabotropic glutamate receptor binding [GO:0031800] 0.84811 0.1293 ADQLTEEQIAEFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5054 0 0 0 0 0 0 P0DP71 F236C_HUMAN Protein FAM236C FAM236C Homo sapiens (Human) 0.9562 -1.5501 GGYRALGI 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2363 0 0 0 0 0 0 0 0 0 0 P0DP75 M14OS_HUMAN Putative uncharacterized protein MED14OS (MED14 antisense gene protein 1) (MED14 opposite strand protein) MED14OS MED14-AS1 Homo sapiens (Human) 0.95499 -1.5683 SPPTPGTGARGGGR 0 0 0 0 0 0 0 9.82279 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0DP91 ERPG3_HUMAN Chimeric ERCC6-PGBD3 protein (Chimeric CSB-PGBD3 protein) ERCC6 Homo sapiens (Human) positive regulation of defense response to virus by host [GO:0002230]; positive regulation of DNA repair [GO:0045739]; positive regulation of gene expression [GO:0010628]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141] nuclear body [GO:0016604]; nucleoplasm [GO:0005654] sequence-specific DNA binding [GO:0043565] 0.84816 0.15438 CSVEYHTE 9.29168 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0DPB3 SCHI1_HUMAN Schwannomin-interacting protein 1 (SCHIP-1) SCHIP1 Homo sapiens (Human) positive regulation of hippo signaling [GO:0035332] cell junction [GO:0030054]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886] identical protein binding [GO:0042802] 0.55851 0.5431 ASSQSNSTK 8.9535 0 8.93943 0 0 0 8.99531 0 9.05983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0DPD5 ZN723_HUMAN Zinc finger protein 723 ZNF723 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.43905 0.64756 AFNQYSTLNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.40782 0 0 0 0 0 0 0 0 0 P0DPD7 EFMT4_HUMAN EEF1A lysine methyltransferase 4 (EC 2.1.1.-) EEF1AKMT4 Homo sapiens (Human) methylation [GO:0032259] methyltransferase activity [GO:0008168]; protein-lysine N-methyltransferase activity [GO:0016279] 0.6715 0.39371 ASPGAGR 0 0 0 0 0 0 8.29866 0 0 0 0 0 0 0 9.19945 9.52734 0 0 0 8.82152 9.1152 0 0 0 0 0 0 P0DPI3 CENL2_HUMAN Centromere protein V-like protein 2 (Centromere protein V pseudogene 2) CENPVL2 CENPVP2 Homo sapiens (Human) carbon-sulfur lyase activity [GO:0016846]; metal ion binding [GO:0046872] 0.88169 -0.30418 LRGLSCEGAAK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.12861 0 0 0 0 0 0 0 0 0 0 0 0 0 P0DQW0 ZC11C_HUMAN Zinc finger CCCH domain-containing protein 11C ZC3H11C Homo sapiens (Human) metal ion binding [GO:0046872] 0.96958 -3.5822 LNCAFHHNRGR 8.69815 0 0 0 0 10.6587 0 0 0 0 9.3439 0 0 0 0 0 0 0 0 0 0 0 9.66502 9.61868 0 0 0 P0DSE1 TRAR1_HUMAN M1-specific T cell receptor alpha chain (TR alpha chain TRAV27*01J42*01C*01) TRA Homo sapiens (Human) adaptive immune response [GO:0002250]; T cell activation involved in immune response [GO:0002286] cell surface [GO:0009986]; T cell receptor complex [GO:0042101] 0.36691 0.7397 DSSLHITAAQPGDTGLYLCAGGGSQGNLIFGK 0 0 0 0 0 0 0 11.1447 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0DTL4 LY6S_HUMAN Lymphocyte antigen 6S LY6S Homo sapiens (Human) plasma membrane [GO:0005886] 0.60776 0.43104 VSVFGSK 9.94461 0 0 0 0 0 0 0 0 10.6314 11.2593 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0DTL6 ZTRF1_HUMAN Zinc finger TRAF-type-containing protein 1 (Cysteine and histidine-rich protein 1) ZFTRAF1 CYHR1 KIAA0496 Homo sapiens (Human) perinuclear region of cytoplasm [GO:0048471] zinc ion binding [GO:0008270] 0.92121 -1.0934 EECQDRVTQCK 0 0 0 10.56 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3984 0 0 P0DUB6 AMY1A_HUMAN "Alpha-amylase 1A (EC 3.2.1.1) (1,4-alpha-D-glucan glucanohydrolase 1) (Salivary alpha-amylase)" AMY1A AMY1 Homo sapiens (Human) oligosaccharide metabolic process [GO:0009311] extracellular exosome [GO:0070062]; extracellular space [GO:0005615] alpha-amylase activity [GO:0004556]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404] 0 35.097 SGNEDEFRNMVTR 0 0 0 0 0 0 0 0 0 12.0185 11.6359 11.639 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P0DV77 TPRX2_HUMAN Tetrapeptide repeat homeobox protein 2 TPRX2 Homo sapiens (Human) maternal-to-zygotic transition of gene expression [GO:0160021] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]" 0.82897 0.20358 VLEFYFQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0957 0 0 0 0 0 P0DW81 PACMP_HUMAN Poly-ADP-ribosylation-amplifying and CtIP-maintaining micropeptide (PAR-amplifying and CtIP-maintaining micropeptide) MARCHF6-DT PACMP Homo sapiens (Human) negative regulation of protein ubiquitination [GO:0031397]; positive regulation of DNA repair [GO:0045739]; regulation of protein ADP-ribosylation [GO:0010835] nucleolus [GO:0005730]; site of DNA damage [GO:0090734] poly-ADP-D-ribose binding [GO:0072572] 0.96174 -2.5603 AASGGTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.37234 0 0 P0DW85 H2BN1_HUMAN Histone H2A.N (H2B.N) (H2B.N variant histone 1) H2BN1 Homo sapiens (Human) nucleosome [GO:0000786]; nucleus [GO:0005634] DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; structural constituent of chromatin [GO:0030527] 0.9159 -0.77636 TELYFPVKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.12293 0 0 P0DX00 GG6LX_HUMAN Golgin subfamily A member 6-like protein 24 GOLGA6L24 Homo sapiens (Human) 0.95989 -1.9045 ELEAQVQTIR 9.74881 9.35867 0 8.85891 8.89724 9.05645 9.05322 9.23795 9.2447 11.6141 11.3028 12.6196 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P10070 GLI2_HUMAN Zinc finger protein GLI2 (GLI family zinc finger protein 2) (Tax helper protein) GLI2 THP Homo sapiens (Human) axon guidance [GO:0007411]; branching morphogenesis of an epithelial tube [GO:0048754]; cellular response to virus [GO:0098586]; cerebellar cortex morphogenesis [GO:0021696]; developmental growth [GO:0048589]; embryonic digestive tract development [GO:0048566]; epidermal cell differentiation [GO:0009913]; floor plate formation [GO:0021508]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; hindbrain development [GO:0030902]; hindgut morphogenesis [GO:0007442]; kidney development [GO:0001822]; lung development [GO:0030324]; mammary gland development [GO:0030879]; negative regulation of hh target transcription factor activity [GO:1990787]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron development [GO:0048666]; odontogenesis of dentin-containing tooth [GO:0042475]; osteoblast development [GO:0002076]; osteoblast differentiation [GO:0001649]; pattern specification process [GO:0007389]; pituitary gland development [GO:0021983]; positive regulation of DNA replication [GO:0045740]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proximal/distal pattern formation [GO:0009954]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; smoothened signaling pathway [GO:0007224]; smoothened signaling pathway involved in ventral spinal cord interneuron specification [GO:0021775]; spinal cord dorsal/ventral patterning [GO:0021513]; spinal cord ventral commissure morphogenesis [GO:0021965]; tube development [GO:0035295]; ventral midline development [GO:0007418]; ventral spinal cord development [GO:0021517] ciliary base [GO:0097546]; ciliary tip [GO:0097542]; cilium [GO:0005929]; cytosol [GO:0005829]; GLI-SUFU complex [GO:1990788]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; zinc ion binding [GO:0008270]" 0.96972 -4.0327 ETSASATASEKQEAK 0 0 0 0 0 0 0 0 0 0 0 9.9737 0 0 9.78261 0 0 0 0 0 0 0 0 0 0 0 0 P10071 GLI3_HUMAN Transcriptional activator GLI3 (GLI3 form of 190 kDa) (GLI3-190) (GLI3 full-length protein) (GLI3FL) [Cleaved into: Transcriptional repressor GLI3R (GLI3 C-terminally truncated form) (GLI3 form of 83 kDa) (GLI3-83)] GLI3 Homo sapiens (Human) alpha-beta T cell differentiation [GO:0046632]; anterior semicircular canal development [GO:0060873]; anterior/posterior pattern specification [GO:0009952]; artery development [GO:0060840]; axon guidance [GO:0007411]; branching involved in ureteric bud morphogenesis [GO:0001658]; camera-type eye morphogenesis [GO:0048593]; cell differentiation involved in kidney development [GO:0061005]; chondrocyte differentiation [GO:0002062]; developmental growth [GO:0048589]; embryonic digestive tract development [GO:0048566]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic digit morphogenesis [GO:0042733]; embryonic neurocranium morphogenesis [GO:0048702]; forebrain dorsal/ventral pattern formation [GO:0021798]; forebrain radial glial cell differentiation [GO:0021861]; frontal suture morphogenesis [GO:0060364]; heart development [GO:0007507]; hindgut morphogenesis [GO:0007442]; hippocampus development [GO:0021766]; in utero embryonic development [GO:0001701]; lambdoid suture morphogenesis [GO:0060366]; larynx morphogenesis [GO:0120223]; lateral ganglionic eminence cell proliferation [GO:0022018]; lateral semicircular canal development [GO:0060875]; layer formation in cerebral cortex [GO:0021819]; limb morphogenesis [GO:0035108]; lung development [GO:0030324]; mammary gland specification [GO:0060594]; melanocyte differentiation [GO:0030318]; metanephros development [GO:0001656]; negative regulation of alpha-beta T cell differentiation [GO:0046639]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hh target transcription factor activity [GO:1990787]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative thymic T cell selection [GO:0045060]; neuroblast proliferation [GO:0007405]; nose morphogenesis [GO:0043585]; odontogenesis of dentin-containing tooth [GO:0042475]; oligodendrocyte differentiation [GO:0048709]; optic nerve morphogenesis [GO:0021631]; osteoblast differentiation [GO:0001649]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein import into nucleus [GO:0006606]; protein processing [GO:0016485]; proximal/distal pattern formation [GO:0009954]; regulation of bone development [GO:1903010]; regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901620]; regulation of transcription by RNA polymerase II [GO:0006357]; roof of mouth development [GO:0060021]; sagittal suture morphogenesis [GO:0060367]; smoothened signaling pathway [GO:0007224]; smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831]; smoothened signaling pathway involved in spinal cord motor neuron cell fate specification [GO:0021776]; smoothened signaling pathway involved in ventral spinal cord interneuron specification [GO:0021775]; stem cell proliferation [GO:0072089]; T cell differentiation in thymus [GO:0033077]; thymocyte apoptotic process [GO:0070242]; tongue development [GO:0043586]; vocalization behavior [GO:0071625] axoneme [GO:0005930]; ciliary base [GO:0097546]; ciliary tip [GO:0097542]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; GLI-SUFU complex [GO:1990788]; intracellular membrane-bounded organelle [GO:0043231]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription repressor complex [GO:0017053] "beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; mediator complex binding [GO:0036033]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.9619 -2.6073 AGSFSISDASCLLQGTSAK 0 0 0 0 10.9304 10.1757 8.18542 0 0 0 14.2435 11.0047 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P10072 ZN875_HUMAN Zinc finger protein 875 (Krueppel-related zinc finger protein 1) (Protein HKR1) ZNF875 HKR1 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.96767 -2.891 GEAPWREER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8126 0 0 0 0 0 0 0 0 0 0 0 P10074 TZAP_HUMAN Telomere zinc finger-associated protein (TZAP) (Krueppel-related zinc finger protein 3) (hKR3) (Zinc finger and BTB domain-containing protein 48) (Zinc finger protein 855) ZBTB48 HKR3 TZAP ZNF855 Homo sapiens (Human) positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]; telomere maintenance via telomere lengthening [GO:0010833] "chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]" DNA-binding transcription factor activity [GO:0003700]; double-stranded telomeric DNA binding [GO:0003691]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; transcription cis-regulatory region binding [GO:0000976] 0.96692 -2.8283 DLQSHMIK 0 0 0 0 0 9.77027 0 13.7162 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.13412 P10124 SRGN_HUMAN Serglycin (Hematopoietic proteoglycan core protein) (Platelet proteoglycan core protein) (P.PG) (Secretory granule proteoglycan core protein) SRGN PRG PRG1 Homo sapiens (Human) apoptotic process [GO:0006915]; biomineral tissue development [GO:0031214]; granzyme-mediated programmed cell death signaling pathway [GO:0140507]; maintenance of granzyme B location in T cell secretory granule [GO:0033382]; maintenance of protease location in mast cell secretory granule [GO:0033373]; mast cell secretory granule organization [GO:0033364]; negative regulation of bone mineralization [GO:0030502]; negative regulation of cytokine production [GO:0001818]; protein processing [GO:0016485]; secretory granule organization [GO:0033363]; T cell secretory granule organization [GO:0033371] cytolytic granule [GO:0044194]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; mast cell granule [GO:0042629]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141] 0.95027 -1.4032 LRTDLFPK 11.7864 11.7474 11.6339 0 0 0 10.3968 10.417 10.5406 0 0 10.4608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P10242 MYB_HUMAN Transcriptional activator Myb (Proto-oncogene c-Myb) MYB Homo sapiens (Human) erythrocyte differentiation [GO:0030218]; mitotic cell cycle [GO:0000278]; myeloid cell development [GO:0061515]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hematopoietic progenitor cell differentiation [GO:1901533]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; T-helper 2 cell differentiation [GO:0045064] cytosol [GO:0005829]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.9259 -0.98282 RWSVIAKHLK 0 0 0 11.0819 11.0156 0 0 0 0 0 0 11.2044 0 0 0 8.89509 0 0 0 0 0 0 0 0 0 0 0 P10243 MYBA_HUMAN Myb-related protein A (A-Myb) (Myb-like protein 1) MYBL1 AMYB Homo sapiens (Human) cell differentiation [GO:0030154]; male meiosis I [GO:0007141]; mitotic cell cycle [GO:0000278]; negative regulation of transposition [GO:0010529]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of piRNA transcription [GO:0140543]; positive regulation of transcription by RNA polymerase II [GO:0045944]; spermatogenesis [GO:0007283] nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.77192 0.2679 SLVLDNWEK 0 0 0 0 0 0 0 0 0 0 9.05444 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P10244 MYBB_HUMAN Myb-related protein B (B-Myb) (Myb-like protein 2) MYBL2 BMYB Homo sapiens (Human) cellular response to leukemia inhibitory factor [GO:1990830]; mitotic cell cycle [GO:0000278]; mitotic spindle assembly [GO:0090307]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944] Myb complex [GO:0031523]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96846 -3.6125 EEDQKVIELVKK 10.1294 10.092 0 0 9.91874 0 0 0 11.7164 11.3483 11.3094 0 0 0 0 0 0 0 0 0 0 9.86556 0 9.96737 0 0 0 P10253 LYAG_HUMAN Lysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase) (Aglucosidase alfa) [Cleaved into: 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase] GAA Homo sapiens (Human) aorta development [GO:0035904]; cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; glucose metabolic process [GO:0006006]; glycogen catabolic process [GO:0005980]; glycophagy [GO:0061723]; heart morphogenesis [GO:0003007]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; maltose metabolic process [GO:0000023]; muscle cell cellular homeostasis [GO:0046716]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; regulation of the force of heart contraction [GO:0002026]; sucrose metabolic process [GO:0005985]; tissue development [GO:0009888]; vacuolar sequestering [GO:0043181] autolysosome lumen [GO:0120282]; azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821] "alpha-1,4-glucosidase activity [GO:0004558]; alpha-glucosidase activity [GO:0090599]; carbohydrate binding [GO:0030246]; maltose alpha-glucosidase activity [GO:0032450]" 0.36817 0.73628 AGYIIPLQGPGLTTTESR 0 0 0 0 0 0 0 0 0 0 0 8.54635 0 0 9.36275 0 0 0 0 0 0 0 0 0 0 0 0 P10323 ACRO_HUMAN Acrosin (EC 3.4.21.10) [Cleaved into: Acrosin light chain; Acrosin heavy chain] ACR ACRS Homo sapiens (Human) acrosome matrix dispersal [GO:0002077]; acrosome reaction [GO:0007340]; activation of adenylate cyclase activity [GO:0007190]; binding of sperm to zona pellucida [GO:0007339]; penetration of zona pellucida [GO:0007341]; response to steroid hormone [GO:0048545]; single fertilization [GO:0007338] acrosomal matrix [GO:0043159]; extracellular region [GO:0005576]; Golgi-associated vesicle [GO:0005798]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] amidase activity [GO:0004040]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; fucose binding [GO:0042806]; mannose binding [GO:0005537]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; zinc ion binding [GO:0008270] 0.91422 -0.81825 AAQHGAWPWMVSLQIFTYNSHR 0 9.85181 0 0 0 8.8173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P10398 ARAF_HUMAN Serine/threonine-protein kinase A-Raf (EC 2.7.11.1) (Proto-oncogene A-Raf) (Proto-oncogene A-Raf-1) (Proto-oncogene Pks) ARAF ARAF1 PKS PKS2 Homo sapiens (Human) negative regulation of apoptotic process [GO:0043066]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; protein modification process [GO:0036211]; protein phosphorylation [GO:0006468]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; regulation of TOR signaling [GO:0032006]; signal transduction [GO:0007165] cytosol [GO:0005829]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.93303 -1.2655 AMRRLLSDCLK 0 0 0 11.5508 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P10412 H14_HUMAN Histone H1.4 (Histone H1b) (Histone H1s-4) H1-4 H1F4 HIST1H1E Homo sapiens (Human) chromosome condensation [GO:0030261]; histone H3-K27 trimethylation [GO:0098532]; histone H3-K4 trimethylation [GO:0080182]; negative regulation of DNA recombination [GO:0045910]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleosome assembly [GO:0006334] heterochromatin [GO:0000792]; nucleosome [GO:0000786]; nucleus [GO:0005634] chromatin DNA binding [GO:0031490]; double-stranded DNA binding [GO:0003690]; nucleosomal DNA binding [GO:0031492]; RNA binding [GO:0003723]; structural constituent of chromatin [GO:0030527] 0 6.8122 ALAAAGYDVEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.89351 0 P10415 BCL2_HUMAN Apoptosis regulator Bcl-2 BCL2 Homo sapiens (Human) "actin filament organization [GO:0007015]; apoptotic process [GO:0006915]; axon regeneration [GO:0031103]; axonogenesis [GO:0007409]; B cell apoptotic process [GO:0001783]; B cell homeostasis [GO:0001782]; B cell lineage commitment [GO:0002326]; B cell proliferation [GO:0042100]; B cell receptor signaling pathway [GO:0050853]; behavioral fear response [GO:0001662]; branching involved in ureteric bud morphogenesis [GO:0001658]; calcium ion transport into cytosol [GO:0060402]; CD8-positive, alpha-beta T cell lineage commitment [GO:0043375]; cell-cell adhesion [GO:0098609]; cellular response to glucose starvation [GO:0042149]; cellular response to hypoxia [GO:0071456]; cellular response to organic substance [GO:0071310]; cochlear nucleus development [GO:0021747]; defense response to virus [GO:0051607]; dendritic cell apoptotic process [GO:0097048]; digestive tract morphogenesis [GO:0048546]; DNA damage response [GO:0006974]; ear development [GO:0043583]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; epithelial cell apoptotic process [GO:1904019]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; female pregnancy [GO:0007565]; focal adhesion assembly [GO:0048041]; G1/S transition of mitotic cell cycle [GO:0000082]; gland morphogenesis [GO:0022612]; glomerulus development [GO:0032835]; hair follicle morphogenesis [GO:0031069]; hematopoietic stem cell differentiation [GO:0060218]; homeostasis of number of cells within a tissue [GO:0048873]; humoral immune response [GO:0006959]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; lymphoid progenitor cell differentiation [GO:0002320]; male gonad development [GO:0008584]; melanin metabolic process [GO:0006582]; melanocyte differentiation [GO:0030318]; mesenchymal cell development [GO:0014031]; metanephros development [GO:0001656]; motor neuron apoptotic process [GO:0097049]; myeloid cell apoptotic process [GO:0033028]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of autophagy [GO:0010507]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of calcium ion transport into cytosol [GO:0010523]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular pH reduction [GO:0032848]; negative regulation of dendritic cell apoptotic process [GO:2000669]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of motor neuron apoptotic process [GO:2000672]; negative regulation of myeloid cell apoptotic process [GO:0033033]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of retinal cell programmed cell death [GO:0046671]; negative regulation of T cell apoptotic process [GO:0070233]; neuron apoptotic process [GO:0051402]; neuron maturation [GO:0042551]; oocyte development [GO:0048599]; organ growth [GO:0035265]; ossification [GO:0001503]; osteoblast proliferation [GO:0033687]; ovarian follicle development [GO:0001541]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; pigment granule organization [GO:0048753]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of melanocyte differentiation [GO:0045636]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of neuron maturation [GO:0014042]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of skeletal muscle fiber development [GO:0048743]; positive regulation of smooth muscle cell migration [GO:0014911]; post-embryonic development [GO:0009791]; protein dephosphorylation [GO:0006470]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of calcium ion transport [GO:0051924]; regulation of cell-matrix adhesion [GO:0001952]; regulation of gene expression [GO:0010468]; regulation of glycoprotein biosynthetic process [GO:0010559]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of nitrogen utilization [GO:0006808]; regulation of protein localization [GO:0032880]; regulation of protein stability [GO:0031647]; regulation of transmembrane transporter activity [GO:0022898]; regulation of viral genome replication [GO:0045069]; release of cytochrome c from mitochondria [GO:0001836]; renal system process [GO:0003014]; response to amino acid [GO:0043200]; response to cytokine [GO:0034097]; response to gamma radiation [GO:0010332]; response to glucocorticoid [GO:0051384]; response to hydrogen peroxide [GO:0042542]; response to iron ion [GO:0010039]; response to ischemia [GO:0002931]; response to nicotine [GO:0035094]; response to radiation [GO:0009314]; response to toxic substance [GO:0009636]; response to UV-B [GO:0010224]; response to xenobiotic stimulus [GO:0009410]; retinal cell programmed cell death [GO:0046666]; skeletal muscle fiber development [GO:0048741]; smooth muscle cell migration [GO:0014909]; spleen development [GO:0048536]; stem cell development [GO:0048864]; T cell apoptotic process [GO:0070231]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]" BAD-BCL-2 complex [GO:0097138]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; pore complex [GO:0046930]; protein-containing complex [GO:0032991] BH3 domain binding [GO:0051434]; channel activity [GO:0015267]; channel inhibitor activity [GO:0016248]; DNA-binding transcription factor binding [GO:0140297]; identical protein binding [GO:0042802]; molecular adaptor activity [GO:0060090]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein phosphatase 2A binding [GO:0051721]; sequence-specific DNA binding [GO:0043565]; ubiquitin protein ligase binding [GO:0031625] 0.96572 -2.3038 QAGDDFSRR 0 0 0 0 0 0 0 10.3422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.97656 P10451 OSTP_HUMAN Osteopontin (Bone sialoprotein 1) (Nephropontin) (Secreted phosphoprotein 1) (SPP-1) (Urinary stone protein) (Uropontin) SPP1 BNSP OPN PSEC0156 Homo sapiens (Human) androgen catabolic process [GO:0006710]; biomineral tissue development [GO:0031214]; cell adhesion [GO:0007155]; cellular response to testosterone stimulus [GO:0071394]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; inflammatory response [GO:0006954]; negative regulation of collateral sprouting of intact axon in response to injury [GO:0048685]; osteoblast differentiation [GO:0001649]; positive regulation of bone resorption [GO:0045780]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of estradiol secretion [GO:2000866]; response to macrophage colony-stimulating factor [GO:0036005]; response to steroid hormone [GO:0048545]; response to vitamin D [GO:0033280] cell projection [GO:0042995]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; perinuclear region of cytoplasm [GO:0048471] cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; integrin binding [GO:0005178]; ion binding [GO:0043167]; small molecule binding [GO:0036094] 0.56494 0.49856 QNLLAPQNAVSSEETNDFK 12.0575 0 11.7084 10.7171 10.9938 0 12.0545 0 10.5286 10.5313 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P10515 ODP2_HUMAN "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (EC 2.3.1.12) (70 kDa mitochondrial autoantigen of primary biliary cirrhosis) (PBC) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (M2 antigen complex 70 kDa subunit) (Pyruvate dehydrogenase complex component E2) (PDC-E2) (PDCE2)" DLAT DLTA Homo sapiens (Human) acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; tricarboxylic acid cycle [GO:0006099] intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrial pyruvate dehydrogenase complex [GO:0005967]; mitochondrion [GO:0005739]; pyruvate dehydrogenase complex [GO:0045254] dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; identical protein binding [GO:0042802] 0.63083 0.40333 DIDSFVPSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.3999 0 P10523 ARRS_HUMAN S-arrestin (48 kDa protein) (Retinal S-antigen) (S-AG) (Rod photoreceptor arrestin) SAG Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor internalization [GO:0002031]; rhodopsin mediated signaling pathway [GO:0016056] cytosol [GO:0005829]; membrane [GO:0016020]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750] G protein-coupled receptor binding [GO:0001664]; opsin binding [GO:0002046]; phosphoprotein binding [GO:0051219]; protein phosphatase inhibitor activity [GO:0004864] 0.56286 0.511 TSKSEPNHVIFKK 10.8378 0 8.70705 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P10586 PTPRF_HUMAN Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) (Leukocyte common antigen related) (LAR) PTPRF LAR Homo sapiens (Human) cell adhesion [GO:0007155]; cell migration [GO:0016477]; negative regulation of receptor binding [GO:1900121]; neuron projection regeneration [GO:0031102]; peptidyl-tyrosine dephosphorylation [GO:0035335]; regulation of axon regeneration [GO:0048679]; synaptic membrane adhesion [GO:0099560]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] extracellular exosome [GO:0070062]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886] cell adhesion molecule binding [GO:0050839]; chondroitin sulfate proteoglycan binding [GO:0035373]; heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]; protein-containing complex binding [GO:0044877]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001] 0.89809 -0.66862 LAAKNRAGLGEEFEK 0 0 0 10.3193 0 0 0 0 0 0 0 0 9.09389 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P10588 NR2F6_HUMAN Nuclear receptor subfamily 2 group F member 6 (V-erbA-related protein 2) (EAR-2) NR2F6 EAR2 ERBAL2 Homo sapiens (Human) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; entrainment of circadian clock by photoperiod [GO:0043153]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron development [GO:0048666] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; nuclear receptor activity [GO:0004879]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; zinc ion binding [GO:0008270]" 0.87101 0.052642 DCQIDQHHRNQCQYCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.83359 0 0 0 0 0 0 0 0 0 P10599 THIO_HUMAN Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP) (allergen Hom s Trx) TXN TRDX TRX TRX1 Homo sapiens (Human) activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-cysteine S-nitrosylation [GO:2000170]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to nitric oxide [GO:0071731]; response to radiation [GO:0009314] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] protein homodimerization activity [GO:0042803]; protein-disulfide reductase (NAD(P)) activity [GO:0047134]; protein-disulfide reductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791] 0 6.9002 LEATINELV 0 0 0 0 0 0 8.97725 9.08847 9.03315 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.74096 P10600 TGFB3_HUMAN Transforming growth factor beta-3 proprotein [Cleaved into: Latency-associated peptide (LAP); Transforming growth factor beta-3 (TGF-beta-3)] TGFB3 Homo sapiens (Human) aging [GO:0007568]; BMP signaling pathway [GO:0030509]; cell-cell junction organization [GO:0045216]; detection of hypoxia [GO:0070483]; digestive tract development [GO:0048565]; embryonic neurocranium morphogenesis [GO:0048702]; face morphogenesis [GO:0060325]; female pregnancy [GO:0007565]; frontal suture morphogenesis [GO:0060364]; in utero embryonic development [GO:0001701]; inner ear development [GO:0048839]; lung alveolus development [GO:0048286]; mammary gland development [GO:0030879]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; odontogenesis [GO:0042476]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein secretion [GO:0050714]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; response to laminar fluid shear stress [GO:0034616]; response to progesterone [GO:0032570]; salivary gland morphogenesis [GO:0007435]; secondary palate development [GO:0062009]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterine wall breakdown [GO:0042704]; wound healing [GO:0042060] cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; T-tubule [GO:0030315]; transforming growth factor beta complex [GO:0099126]; transforming growth factor beta ligand-receptor complex [GO:0070021] cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; transforming growth factor beta binding [GO:0050431]; type I transforming growth factor beta receptor binding [GO:0034713]; type II transforming growth factor beta receptor binding [GO:0005114]; type III transforming growth factor beta receptor binding [GO:0034714] 0.88906 -0.42957 RVEAIRGQILSK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.2078 0 0 0 0 0 0 0 0 0 0 9.6024 0 9.55296 P10606 COX5B_HUMAN "Cytochrome c oxidase subunit 5B, mitochondrial (Cytochrome c oxidase polypeptide Vb)" COX5B Homo sapiens (Human) "cellular respiration [GO:0045333]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; respiratory gaseous exchange by respiratory system [GO:0007585]" mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739] cytochrome-c oxidase activity [GO:0004129]; metal ion binding [GO:0046872] 0.8897 -0.49867 GAGTLAAQALR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5383 0 0 0 0 0 0 0 0 0 0 0 0 P10619 PPGB_HUMAN Lysosomal protective protein (EC 3.4.16.5) (Carboxypeptidase C) (Carboxypeptidase L) (Cathepsin A) (Protective protein cathepsin A) (PPCA) (Protective protein for beta-galactosidase) [Cleaved into: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain] CTSA PPGB Homo sapiens (Human) intracellular protein transport [GO:0006886]; negative regulation of chaperone-mediated autophagy [GO:1904715]; proteolysis [GO:0006508]; regulation of chaperone-mediated autophagy [GO:1904714]; regulation of protein stability [GO:0031647] azurophil granule lumen [GO:0035578]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; membrane [GO:0016020] carboxypeptidase activity [GO:0004180]; enzyme activator activity [GO:0008047]; serine-type carboxypeptidase activity [GO:0004185] 0.79627 0.24333 EFSHIAFLTIK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.30615 0 0 0 0 0 0 0 0 0 0 0 0 0 P10620 MGST1_HUMAN Microsomal glutathione S-transferase 1 (Microsomal GST-1) (EC 2.5.1.18) (Microsomal GST-I) MGST1 GST12 MGST Homo sapiens (Human) cellular response to lipid hydroperoxide [GO:0071449]; glutathione transport [GO:0034635] azurophil granule membrane [GO:0035577]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; peroxisomal membrane [GO:0005778]; plasma membrane [GO:0005886] glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364] 0.0084507 2.2399 IYHTIAYLTPLPQPNR 0 0 0 0 0 0 9.22468 0 0 0 0 0 10.6529 10.6284 10.7816 0 10.3685 0 0 8.79019 0 0 0 0 0 0 0 P10632 CP2C8_HUMAN Cytochrome P450 2C8 (EC 1.14.14.1) (CYPIIC8) (Cytochrome P450 IIC2) (Cytochrome P450 MP-12) (Cytochrome P450 MP-20) (Cytochrome P450 form 1) (S-mephenytoin 4-hydroxylase) CYP2C8 Homo sapiens (Human) epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; icosanoid biosynthetic process [GO:0046456]; lipid hydroxylation [GO:0002933]; long-chain fatty acid biosynthetic process [GO:0042759]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; oxidative demethylation [GO:0070989]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805] cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886] "arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; caffeine oxidase activity [GO:0034875]; estrogen 16-alpha-hydroxylase activity [GO:0101020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; retinoic acid 4-hydroxylase activity [GO:0008401]" 0.72892 0.33357 GLGIISSNGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.99704 0 0 10.6452 10.37 10.5777 0 0 0 P10635 CP2D6_HUMAN Cytochrome P450 2D6 (EC 1.14.14.-) (CYPIID6) (Cholesterol 25-hydroxylase) (Cytochrome P450-DB1) (Debrisoquine 4-hydroxylase) CYP2D6 CYP2DL1 Homo sapiens (Human) alkaloid catabolic process [GO:0009822]; alkaloid metabolic process [GO:0009820]; arachidonic acid metabolic process [GO:0019369]; cholesterol metabolic process [GO:0008203]; coumarin metabolic process [GO:0009804]; estrogen metabolic process [GO:0008210]; heterocycle metabolic process [GO:0046483]; isoquinoline alkaloid metabolic process [GO:0033076]; long-chain fatty acid biosynthetic process [GO:0042759]; monoterpenoid metabolic process [GO:0016098]; negative regulation of binding [GO:0051100]; negative regulation of cellular organofluorine metabolic process [GO:0090350]; oxidative demethylation [GO:0070989]; retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805] cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739] "anandamide 11,12 epoxidase activity [GO:0062188]; anandamide 14,15 epoxidase activity [GO:0062189]; anandamide 8,9 epoxidase activity [GO:0062187]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]" 0.84991 0.16535 SQGVFLAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2511 P10636 TAU_HUMAN Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau) MAPT MAPTL MTBT1 TAU Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; amyloid fibril formation [GO:1990000]; astrocyte activation [GO:0048143]; axon development [GO:0061564]; axonal transport [GO:0098930]; axonal transport of mitochondrion [GO:0019896]; cell-cell signaling [GO:0007267]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to heat [GO:0034605]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to reactive oxygen species [GO:0034614]; central nervous system neuron development [GO:0021954]; cytoplasmic microtubule organization [GO:0031122]; DNA damage response [GO:0006974]; generation of neurons [GO:0048699]; internal protein amino acid acetylation [GO:0006475]; intracellular distribution of mitochondria [GO:0048312]; learning or memory [GO:0007611]; memory [GO:0007613]; microglial cell activation [GO:0001774]; microtubule cytoskeleton organization [GO:0000226]; microtubule polymerization [GO:0046785]; negative regulation of establishment of protein localization to mitochondrion [GO:1903748]; negative regulation of gene expression [GO:0010629]; negative regulation of kinase activity [GO:0033673]; negative regulation of mitochondrial fission [GO:0090258]; negative regulation of mitochondrial membrane potential [GO:0010917]; negative regulation of tubulin deacetylation [GO:1904428]; neurofibrillary tangle assembly [GO:1902988]; neuron projection development [GO:0031175]; plus-end-directed organelle transport along microtubule [GO:0072386]; positive regulation of axon extension [GO:0045773]; positive regulation of diacylglycerol kinase activity [GO:1905689]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization [GO:1903829]; positive regulation of protein localization to synapse [GO:1902474]; positive regulation of superoxide anion generation [GO:0032930]; protein homooligomerization [GO:0051260]; protein polymerization [GO:0051258]; regulation of autophagy [GO:0010506]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cellular response to heat [GO:1900034]; regulation of chromosome organization [GO:0033044]; regulation of long-term synaptic depression [GO:1900452]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of microtubule polymerization [GO:0031113]; regulation of microtubule polymerization or depolymerization [GO:0031110]; regulation of mitochondrial fission [GO:0090140]; regulation of synaptic plasticity [GO:0048167]; response to lead ion [GO:0010288]; rRNA metabolic process [GO:0016072]; stress granule assembly [GO:0034063]; supramolecular fiber organization [GO:0097435]; synapse assembly [GO:0007416]; synapse organization [GO:0050808] axolemma [GO:0030673]; axon [GO:0030424]; axon cytoplasm [GO:1904115]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; glial cell projection [GO:0097386]; growth cone [GO:0030426]; main axon [GO:0044304]; membrane raft [GO:0045121]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; neurofibrillary tangle [GO:0097418]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nuclear periphery [GO:0034399]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; somatodendritic compartment [GO:0036477]; tubulin complex [GO:0045298] actin binding [GO:0003779]; apolipoprotein binding [GO:0034185]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; dynactin binding [GO:0034452]; enzyme binding [GO:0019899]; histone-dependent DNA binding [GO:0099077]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipoprotein particle binding [GO:0071813]; microtubule binding [GO:0008017]; microtubule lateral binding [GO:0099609]; minor groove of adenine-thymine-rich DNA binding [GO:0003680]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol bisphosphate binding [GO:1902936]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein-folding chaperone binding [GO:0051087]; protein-macromolecule adaptor activity [GO:0030674]; RNA binding [GO:0003723]; sequence-specific DNA binding [GO:0043565]; SH3 domain binding [GO:0017124]; single-stranded DNA binding [GO:0003697] 0.95918 -1.8646 GAGGKERPGSKEEVDEDR 0 8.54187 0 8.24151 0 0 0 0 0 0 9.94685 0 0 0 0 8.68317 8.60807 8.75906 0 9.76616 0 10.7994 0 9.1458 0 0 0 P10643 CO7_HUMAN Complement component C7 C7 Homo sapiens (Human) "complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; killing of cells of another organism [GO:0031640]; positive regulation of immune response [GO:0050778]" extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579] 0.95959 -1.8855 EQTMSECEAGALR 0 0 0 11.6098 0 0 0 0 0 0 0 0 0 0 11.4306 0 0 0 0 0 0 0 0 0 0 0 0 P10644 KAP0_HUMAN cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue-specific extinguisher 1) (TSE1) PRKAR1A PKR1 PRKAR1 TSE1 Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cardiac muscle cell proliferation [GO:0060038]; cellular response to glucagon stimulus [GO:0071377]; intracellular signal transduction [GO:0035556]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of cAMP-dependent protein kinase activity [GO:2000480]; negative regulation of gene expression [GO:0010629]; positive regulation of insulin secretion [GO:0032024]; regulation of transcription by RNA polymerase II [GO:0006357]; sarcomere organization [GO:0045214] cAMP-dependent protein kinase complex [GO:0005952]; centrosome [GO:0005813]; ciliary base [GO:0097546]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; multivesicular body [GO:0005771]; neuromuscular junction [GO:0031594]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane raft [GO:0044853]; protein-containing complex [GO:0032991]; sperm connecting piece [GO:0097224] cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; cAMP-dependent protein kinase regulator activity [GO:0008603]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625] 0.44087 0.64787 ILMGSTLRK 0 0 0 0 0 0 0 0 0 8.93717 0 0 0 10.6184 0 0 0 0 0 0 0 0 0 0 0 0 0 P10696 PPBN_HUMAN "Alkaline phosphatase, germ cell type (EC 3.1.3.1) (ALP-1) (Alkaline phosphatase Nagao isozyme) (Alkaline phosphatase, placental-like) (Germ cell alkaline phosphatase) (GCAP) (Placental alkaline phosphatase-like) (PLAP-like)" ALPG ALPPL ALPPL2 Homo sapiens (Human) dephosphorylation [GO:0016311] extracellular region [GO:0005576]; plasma membrane [GO:0005886] alkaline phosphatase activity [GO:0004035]; metal ion binding [GO:0046872] 0.95904 -1.7701 IDHGHHESRAYR 0 9.86669 0 0 0 0 0 0 0 9.66482 0 9.70248 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P10721 KIT_HUMAN Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117) KIT SCFR Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; B cell differentiation [GO:0030183]; cell chemotaxis [GO:0060326]; cellular response to thyroid hormone stimulus [GO:0097067]; cytokine-mediated signaling pathway [GO:0019221]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; digestive tract development [GO:0048565]; ectopic germ cell programmed cell death [GO:0035234]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation [GO:0050673]; erythrocyte differentiation [GO:0030218]; erythropoietin-mediated signaling pathway [GO:0038162]; Fc receptor signaling pathway [GO:0038093]; germ cell migration [GO:0008354]; glycosphingolipid metabolic process [GO:0006687]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell migration [GO:0035701]; hemopoiesis [GO:0030097]; immature B cell differentiation [GO:0002327]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; Kit signaling pathway [GO:0038109]; lamellipodium assembly [GO:0030032]; lymphoid progenitor cell differentiation [GO:0002320]; male gonad development [GO:0008584]; mast cell chemotaxis [GO:0002551]; mast cell degranulation [GO:0043303]; mast cell differentiation [GO:0060374]; mast cell proliferation [GO:0070662]; megakaryocyte development [GO:0035855]; melanocyte adhesion [GO:0097326]; melanocyte differentiation [GO:0030318]; melanocyte migration [GO:0097324]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of developmental process [GO:0051093]; negative regulation of programmed cell death [GO:0043069]; negative regulation of reproductive process [GO:2000242]; ovarian follicle development [GO:0001541]; peptidyl-tyrosine phosphorylation [GO:0018108]; pigmentation [GO:0043473]; positive regulation of cell migration [GO:0030335]; positive regulation of colon smooth muscle contraction [GO:1904343]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mast cell cytokine production [GO:0032765]; positive regulation of mast cell proliferation [GO:0070668]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of pyloric antrum smooth muscle contraction [GO:0120072]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of small intestine smooth muscle contraction [GO:1904349]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular associated smooth muscle cell differentiation [GO:1905065]; protein autophosphorylation [GO:0046777]; regulation of bile acid metabolic process [GO:1904251]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; response to cadmium ion [GO:0046686]; signal transduction [GO:0007165]; somatic stem cell division [GO:0048103]; somatic stem cell population maintenance [GO:0035019]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]; stem cell population maintenance [GO:0019827]; T cell differentiation [GO:0030217]; tongue development [GO:0043586]; visual learning [GO:0008542] acrosomal vesicle [GO:0001669]; cell-cell junction [GO:0005911]; cytoplasmic side of plasma membrane [GO:0009898]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; fibrillar center [GO:0001650]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] ATP binding [GO:0005524]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; metal ion binding [GO:0046872]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; stem cell factor receptor activity [GO:0005020]; transmembrane receptor protein tyrosine kinase activity [GO:0004714] 0.95523 -1.5553 DLRFIPDPK 10.1816 10.4899 10.2207 0 0 0 9.32546 9.75131 0 9.72588 0 9.63292 0 0 0 0 12.0972 9.63203 0 10.4523 0 0 0 0 0 0 0 P10746 HEM4_HUMAN Uroporphyrinogen-III synthase (UROIIIS) (UROS) (EC 4.2.1.75) (Hydroxymethylbilane hydrolyase [cyclizing]) (Uroporphyrinogen-III cosynthase) UROS Homo sapiens (Human) cellular response to amine stimulus [GO:0071418]; cellular response to arsenic-containing substance [GO:0071243]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]; response to antibiotic [GO:0046677]; response to platinum ion [GO:0070541]; uroporphyrinogen III biosynthetic process [GO:0006780] cytosol [GO:0005829]; mitochondrion [GO:0005739] folic acid binding [GO:0005542]; uroporphyrinogen-III synthase activity [GO:0004852] 0.87188 0.060504 HIQELSGDNIDQIK 0 0 0 0 0 0 0 0 0 0 0 0 10.2275 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P10747 CD28_HUMAN T-cell-specific surface glycoprotein CD28 (TP44) (CD antigen CD28) CD28 Homo sapiens (Human) "apoptotic signaling pathway [GO:0097190]; CD4-positive, alpha-beta T cell proliferation [GO:0035739]; cell surface receptor signaling pathway [GO:0007166]; humoral immune response [GO:0006959]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; negative thymic T cell selection [GO:0045060]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of cytokine production [GO:0001819]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response to antigenic stimulus [GO:0002863]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of viral genome replication [GO:0045070]; protein kinase B signaling [GO:0043491]; regulation of regulatory T cell differentiation [GO:0045589]; regulatory T cell differentiation [GO:0045066]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; transcription by RNA polymerase II [GO:0006366]" cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636] coreceptor activity [GO:0015026]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein kinase binding [GO:0019901] 0.94711 -1.3552 RSRLLHSDYMNMTPR 0 0 0 0 0 0 0 0 10.8764 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P10768 ESTD_HUMAN S-formylglutathione hydrolase (FGH) (EC 3.1.2.12) (Esterase D) (Methylumbelliferyl-acetate deacetylase) (EC 3.1.1.56) ESD Homo sapiens (Human) formaldehyde catabolic process [GO:0046294] cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062] "carboxylic ester hydrolase activity [GO:0052689]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; S-formylglutathione hydrolase activity [GO:0018738]" 0.94916 -1.3716 AYDATHLVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.23788 0 0 0 0 P10809 CH60_HUMAN "60 kDa heat shock protein, mitochondrial (EC 5.6.1.7) (60 kDa chaperonin) (Chaperonin 60) (CPN60) (Heat shock protein 60) (HSP-60) (Hsp60) (HuCHA60) (Mitochondrial matrix protein P1) (P60 lymphocyte protein)" HSPD1 HSP60 Homo sapiens (Human) 'de novo' protein folding [GO:0006458]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic mitochondrial changes [GO:0008637]; B cell activation [GO:0042113]; B cell proliferation [GO:0042100]; biological process involved in interaction with symbiont [GO:0051702]; cellular response to interleukin-7 [GO:0098761]; chaperone-mediated protein complex assembly [GO:0051131]; isotype switching to IgG isotypes [GO:0048291]; mitochondrial unfolded protein response [GO:0034514]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; negative regulation of apoptotic process [GO:0043066]; positive regulation of apoptotic process [GO:0043065]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of macrophage activation [GO:0043032]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell mediated immune response to tumor cell [GO:0002842]; positive regulation of type II interferon production [GO:0032729]; protein folding [GO:0006457]; protein import into mitochondrial intermembrane space [GO:0045041]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; response to cold [GO:0009409]; response to unfolded protein [GO:0006986]; T cell activation [GO:0042110] cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; coated vesicle [GO:0030135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; lipopolysaccharide receptor complex [GO:0046696]; membrane [GO:0016020]; migrasome [GO:0140494]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; sperm midpiece [GO:0097225]; sperm plasma membrane [GO:0097524] apolipoprotein A-I binding [GO:0034186]; apolipoprotein binding [GO:0034185]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; DNA replication origin binding [GO:0003688]; double-stranded RNA binding [GO:0003725]; enzyme binding [GO:0019899]; high-density lipoprotein particle binding [GO:0008035]; isomerase activity [GO:0016853]; lipopolysaccharide binding [GO:0001530]; p53 binding [GO:0002039]; protein-folding chaperone binding [GO:0051087]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082] 0 169.42 AAVEEGIVLGGGCALLR 13.9257 13.6857 13.7883 0 10.066 0 13.7916 13.5048 13.6876 13.3824 13.4022 13.2524 9.98783 8.99786 11.4587 11.3328 11.8789 10.7577 12.0809 12.4327 12.8349 12.4273 12.951 12.8912 14.1727 14.1567 14.129 P10827 THA_HUMAN Thyroid hormone receptor alpha (Nuclear receptor subfamily 1 group A member 1) (V-erbA-related protein 7) (EAR-7) (c-erbA-1) (c-erbA-alpha) THRA EAR7 ERBA1 NR1A1 THRA1 THRA2 Homo sapiens (Human) cartilage condensation [GO:0001502]; cell differentiation [GO:0030154]; erythrocyte differentiation [GO:0030218]; female courtship behavior [GO:0008050]; hormone-mediated signaling pathway [GO:0009755]; learning or memory [GO:0007611]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of DNA-templated transcription initiation [GO:2000143]; negative regulation of RNA polymerase II transcription preinitiation complex assembly [GO:0017055]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of female receptivity [GO:0045925]; positive regulation of thyroid hormone mediated signaling pathway [GO:0002157]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of heart contraction [GO:0008016]; regulation of lipid catabolic process [GO:0050994]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of thyroid hormone mediated signaling pathway [GO:0002155]; regulation of transcription by RNA polymerase II [GO:0006357]; response to cold [GO:0009409]; retinoic acid receptor signaling pathway [GO:0048384]; thyroid gland development [GO:0030878]; thyroid hormone mediated signaling pathway [GO:0002154]; transcription by RNA polymerase II [GO:0006366]; type I pneumocyte differentiation [GO:0060509] chromatin [GO:0000785]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575] "chromatin DNA binding [GO:0031490]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; general transcription initiation factor binding [GO:0140296]; nuclear receptor activity [GO:0004879]; protein domain specific binding [GO:0019904]; protein-containing complex binding [GO:0044877]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; TBP-class protein binding [GO:0017025]; thyroid hormone binding [GO:0070324]; transcription cis-regulatory region binding [GO:0000976]; zinc ion binding [GO:0008270]" 0.96302 -2.1876 CIAVGMAMDLVLDDSKR 0 10.6896 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0025 0 0 0 0 9.41857 0 0 0 P10828 THB_HUMAN Thyroid hormone receptor beta (Nuclear receptor subfamily 1 group A member 2) (c-erbA-2) (c-erbA-beta) THRB ERBA2 NR1A2 THR1 Homo sapiens (Human) cell differentiation [GO:0030154]; cellular response to thyroid hormone stimulus [GO:0097067]; DNA-templated transcription [GO:0006351]; female courtship behavior [GO:0008050]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of female receptivity [GO:0007621]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of thyroid hormone mediated signaling pathway [GO:0002157]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of heart contraction [GO:0008016]; retinal cone cell apoptotic process [GO:0097474]; retinal cone cell development [GO:0046549]; retinoic acid receptor signaling pathway [GO:0048384]; sensory perception of sound [GO:0007605]; thyroid hormone mediated signaling pathway [GO:0002154]; type I pneumocyte differentiation [GO:0060509] chromatin [GO:0000785]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575] "chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; nuclear receptor activity [GO:0004879]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]; thyroid hormone binding [GO:0070324]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]" 0.91302 -0.78644 CIYVGMATDLVLDDSKR 15.7228 0 0 0 0 14.1886 0 15.4416 0 15.018 0 14.9728 0 0 0 0 0 8.72048 0 0 0 0 0 0 0 0 0 P10909 CLUS_HUMAN "Clusterin (Aging-associated gene 4 protein) (Apolipoprotein J) (Apo-J) (Complement cytolysis inhibitor) (CLI) (Complement-associated protein SP-40,40) (Ku70-binding protein 1) (NA1/NA2) (Sulfated glycoprotein 2) (SGP-2) (Testosterone-repressed prostate message 2) (TRPM-2) [Cleaved into: Clusterin beta chain (ApoJalpha) (Complement cytolysis inhibitor a chain) (SP-40,40 beta-chain); Clusterin alpha chain (ApoJbeta) (Complement cytolysis inhibitor b chain) (SP-40,40 alpha-chain)]" CLU APOJ CLI KUB1 AAG4 Homo sapiens (Human) "cell morphogenesis [GO:0000902]; central nervous system myelin maintenance [GO:0032286]; chaperone-mediated protein complex assembly [GO:0051131]; chaperone-mediated protein folding [GO:0061077]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; immune complex clearance [GO:0002434]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway [GO:0097193]; lipid metabolic process [GO:0006629]; microglial cell activation [GO:0001774]; microglial cell proliferation [GO:0061518]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of response to endoplasmic reticulum stress [GO:1903573]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of gene expression [GO:0010628]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of neurofibrillary tangle assembly [GO:1902998]; positive regulation of neuron death [GO:1901216]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein-containing complex assembly [GO:0031334]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein import [GO:0017038]; protein stabilization [GO:0050821]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; regulation of amyloid-beta clearance [GO:1900221]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of neuron death [GO:1901214]; regulation of neuronal signal transduction [GO:1902847]; release of cytochrome c from mitochondria [GO:0001836]; response to misfolded protein [GO:0051788]; response to virus [GO:0009615]; reverse cholesterol transport [GO:0043691]" apical dendrite [GO:0097440]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; chromaffin granule [GO:0042583]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neurofibrillary tangle [GO:0097418]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum lumen [GO:0099020]; perinuclear region of cytoplasm [GO:0048471]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; spherical high-density lipoprotein particle [GO:0034366]; synapse [GO:0045202] amyloid-beta binding [GO:0001540]; low-density lipoprotein particle receptor binding [GO:0050750]; misfolded protein binding [GO:0051787]; protein carrier chaperone [GO:0140597]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; protein-folding chaperone binding [GO:0051087]; signaling receptor binding [GO:0005102]; tau protein binding [GO:0048156]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082] 0.7645 0.2812 FMETVAEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9902 0 0 P10911 MCF2_HUMAN Proto-oncogene DBL (Proto-oncogene MCF-2) [Cleaved into: MCF2-transforming protein; DBL-transforming protein] MCF2 DBL Homo sapiens (Human) cellular response to leukemia inhibitory factor [GO:1990830]; dendrite development [GO:0016358]; intracellular signal transduction [GO:0035556]; negative regulation of axonogenesis [GO:0050771]; regulation of small GTPase mediated signal transduction [GO:0051056] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020] guanyl-nucleotide exchange factor activity [GO:0005085] 0.96936 -3.5442 DLARFKPMQR 0 0 0 0 9.53995 10.8566 0 14.7908 0 0 0 0 13.623 13.748 0 14.184 0 0 0 0 0 0 9.32542 0 0 0 0 P10914 IRF1_HUMAN Interferon regulatory factor 1 (IRF-1) IRF1 Homo sapiens (Human) "apoptotic process [GO:0006915]; CD8-positive, alpha-beta T cell differentiation [GO:0043374]; cellular response to interferon-beta [GO:0035458]; cellular response to mechanical stimulus [GO:0071260]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of regulatory T cell differentiation [GO:0045590]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of adaptive immune response [GO:0002819]; regulation of CD8-positive, alpha-beta T cell proliferation [GO:2000564]; regulation of cell cycle [GO:0051726]; regulation of innate immune response [GO:0045088]; regulation of MyD88-dependent toll-like receptor signaling pathway [GO:0034124]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366]; type II interferon-mediated signaling pathway [GO:0060333]" chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; transcription cis-regulatory region binding [GO:0000976]" 0.93365 -1.2825 AGEKEPDPKTWK 0 0 0 0 0 0 0 0 0 0 9.77563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P10915 HPLN1_HUMAN Hyaluronan and proteoglycan link protein 1 (Cartilage-linking protein 1) (Cartilage-link protein) (Proteoglycan link protein) HAPLN1 CRTL1 Homo sapiens (Human) cell adhesion [GO:0007155]; glial cell differentiation [GO:0010001]; positive regulation of neuroblast proliferation [GO:0002052] collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perineuronal net [GO:0072534]; synapse [GO:0045202] hyaluronic acid binding [GO:0005540] 0.92221 -1.1198 EPCGGQNTVPGVRNYGFWDKDK 0 0 0 0 0 0 0 0 10.6862 0 0 0 0 0 0 0 0 0 0 0 0 9.49221 9.537 0 0 0 0 P10966 CD8B_HUMAN T-cell surface glycoprotein CD8 beta chain (CD antigen CD8b) CD8B CD8B1 Homo sapiens (Human) adaptive immune response [GO:0002250]; immune response [GO:0006955]; T cell activation [GO:0042110]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] cell surface [GO:0009986]; early endosome membrane [GO:0031901]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; T cell receptor complex [GO:0042101] coreceptor activity [GO:0015026]; MHC class I protein binding [GO:0042288] 0.86397 0.087088 ISLSNMRIYWLR 9.49247 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P11021 BIP_HUMAN Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein) HSPA5 GRP78 Homo sapiens (Human) "cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to xenobiotic stimulus [GO:0071466]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; post-translational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]" cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; protein-folding chaperone binding [GO:0051087]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082] 0 233.77 AKFEELNMDLFR 14.1897 14.1586 13.9145 0 10.9863 10.2107 13.188 13.5228 13.6311 14.812 14.8049 14.8043 12.7732 13.4914 12.5067 13.1322 12.8929 12.3611 14.7304 15.0351 14.8935 13.1341 13.3906 12.7729 14.6621 14.5518 13.6265 P11047 LAMC1_HUMAN Laminin subunit gamma-1 (Laminin B2 chain) (Laminin-1 subunit gamma) (Laminin-10 subunit gamma) (Laminin-11 subunit gamma) (Laminin-2 subunit gamma) (Laminin-3 subunit gamma) (Laminin-4 subunit gamma) (Laminin-6 subunit gamma) (Laminin-7 subunit gamma) (Laminin-8 subunit gamma) (Laminin-9 subunit gamma) (S-laminin subunit gamma) (S-LAM gamma) LAMC1 LAMB2 Homo sapiens (Human) cell adhesion [GO:0007155]; cell migration [GO:0016477]; endoderm development [GO:0007492]; extracellular matrix disassembly [GO:0022617]; hemidesmosome assembly [GO:0031581]; maintenance of blood-brain barrier [GO:0035633]; positive regulation of cell adhesion [GO:0045785]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; protein-containing complex assembly [GO:0065003]; regulation of basement membrane organization [GO:0110011]; substrate adhesion-dependent cell spreading [GO:0034446] basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; laminin-1 complex [GO:0005606]; laminin-10 complex [GO:0043259]; laminin-11 complex [GO:0043260]; protein complex involved in cell-matrix adhesion [GO:0098637] extracellular matrix structural constituent [GO:0005201] 0 193.13 AFDITYVR 14.0383 13.9736 13.8818 11.9161 12.2136 12.0668 13.6398 13.78 13.7185 13.5169 13.2577 15.2203 11.3813 10.8792 11.4113 12.2176 12.1818 11.3922 10.9585 10.7293 11.0462 11.2466 10.3444 10.5051 11.6363 11.4525 11.3408 P11049 CD37_HUMAN Leukocyte antigen CD37 (Tetraspanin-26) (Tspan-26) (CD antigen CD37) CD37 TSPAN26 Homo sapiens (Human) extracellular exosome [GO:0070062]; immunological synapse [GO:0001772]; membrane [GO:0016020] 0.96747 -2.8583 NLDHVYNRLARYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4346 0 0 0 0 0 0 0 0 0 P11055 MYH3_HUMAN "Myosin-3 (Muscle embryonic myosin heavy chain) (Myosin heavy chain 3) (Myosin heavy chain, fast skeletal muscle, embryonic) (SMHCE)" MYH3 Homo sapiens (Human) actin filament-based movement [GO:0030048]; ATP metabolic process [GO:0046034]; embryonic limb morphogenesis [GO:0030326]; face morphogenesis [GO:0060325]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; muscle organ development [GO:0007517]; sarcomere organization [GO:0045214]; skeletal muscle contraction [GO:0003009] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; muscle myosin complex [GO:0005859]; myosin filament [GO:0032982]; myosin II complex [GO:0016460]; sarcomere [GO:0030017] actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; calmodulin binding [GO:0005516]; microfilament motor activity [GO:0000146]; myosin phosphatase activity [GO:0017018] 0.91828 -0.8561 ADIAESQVNK 11.8638 0 0 0 0 0 0 0 0 9.28492 0 0 8.59178 0 8.61776 0 0 0 0 0 0 10.0451 10.1803 9.42524 0 0 9.94109 P11086 PNMT_HUMAN Phenylethanolamine N-methyltransferase (PNMTase) (EC 2.1.1.28) (Noradrenaline N-methyltransferase) PNMT PENT Homo sapiens (Human) catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]; methylation [GO:0032259] cytosol [GO:0005829] phenylethanolamine N-methyltransferase activity [GO:0004603] 0.78172 0.26138 GVFFAWAQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.96454 0 0 0 9.32312 0 0 0 P11137 MTAP2_HUMAN Microtubule-associated protein 2 (MAP-2) MAP2 Homo sapiens (Human) central nervous system neuron development [GO:0021954]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of axon extension [GO:0030517]; negative regulation of microtubule binding [GO:1904527]; negative regulation of microtubule polymerization [GO:0031115]; neuron projection development [GO:0031175]; positive regulation of anterograde dense core granule transport [GO:1901953]; positive regulation of anterograde synaptic vesicle transport [GO:1903744]; regulation of microtubule polymerization [GO:0031113]; regulation of organelle transport along microtubule [GO:1902513]; regulation of protein localization [GO:0032880] apical distal dendrite [GO:0150014]; axon hillock [GO:0043203]; axon initial segment [GO:0043194]; basal dendrite [GO:0097441]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic branch [GO:0044307]; dendritic filopodium [GO:1902737]; dendritic growth cone [GO:0044294]; dendritic shaft [GO:0043198]; distal dendrite [GO:0150002]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; primary dendrite [GO:0150001]; proximal dendrite [GO:1990635]; proximal neuron projection [GO:1990769] calmodulin binding [GO:0005516]; dystroglycan binding [GO:0002162]; microtubule binding [GO:0008017]; structural molecule activity [GO:0005198]; tau protein binding [GO:0048156] 0.96371 -2.6516 DKVSDGVTKSPEK 0 0 0 0 0 11.9355 0 0 0 12.8713 0 0 9.43365 0 0 0 0 11.5407 0 0 0 0 0 0 11.988 10.3604 0 P11142 HSP7C_HUMAN Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1) HSPA8 HSC70 HSP73 HSPA10 Homo sapiens (Human) "ATP metabolic process [GO:0046034]; cellular response to starvation [GO:0009267]; cellular response to steroid hormone stimulus [GO:0071383]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; clathrin coat disassembly [GO:0072318]; late endosomal microautophagy [GO:0061738]; membrane organization [GO:0061024]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of supramolecular fiber organization [GO:1902904]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; protein folding [GO:0006457]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; regulation of cell cycle [GO:0051726]; regulation of postsynapse organization [GO:0099175]; regulation of protein complex stability [GO:0061635]; regulation of protein import [GO:1904589]; regulation of protein stability [GO:0031647]; regulation of protein-containing complex assembly [GO:0043254]; response to unfolded protein [GO:0006986]; slow axonal transport [GO:1990832]" autophagosome [GO:0005776]; blood microparticle [GO:0072562]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; glycinergic synapse [GO:0098690]; late endosome [GO:0005770]; lumenal side of lysosomal membrane [GO:0098575]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor ribbon synapse [GO:0098684]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; postsynaptic specialization membrane [GO:0099634]; presynaptic cytosol [GO:0099523]; protein folding chaperone complex [GO:0101031]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein disaggregase activity [GO:0140545]; ATP-dependent protein folding chaperone [GO:0140662]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; clathrin-uncoating ATPase activity [GO:1990833]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; MHC class II protein complex binding [GO:0023026]; phosphatidylserine binding [GO:0001786]; protein carrier chaperone [GO:0140597]; protein folding chaperone [GO:0044183]; protein-folding chaperone binding [GO:0051087]; protein-macromolecule adaptor activity [GO:0030674]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082] 0 274.95 ARFEELNADLFR 13.2535 13.0294 13.4047 0 0 0 12.7741 12.6826 12.6936 14.9512 14.9241 14.9049 13.2187 13.2195 12.9238 13.221 13.3836 12.9655 13.8673 13.9748 14.2737 13.324 13.0381 12.7559 14.414 14.4322 14.4041 P11171 EPB41_HUMAN Protein 4.1 (P4.1) (4.1R) (Band 4.1) (EPB4.1) (Erythrocyte membrane protein band 4.1) EPB41 E41P Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; regulation of calcium ion transport [GO:0051924]; regulation of intestinal absorption [GO:1904478] basolateral plasma membrane [GO:0016323]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cortical cytoskeleton [GO:0030863]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; spectrin-associated cytoskeleton [GO:0014731] 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; phosphoprotein binding [GO:0051219]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200] 0.96412 -2.4099 GGISETRIEK 16.5321 0 0 12.9516 13.6369 12.5609 16.3116 16.4698 0 0 0 0 0 0 10.3114 0 0 14.7187 0 10.4949 12.7332 12.833 12.2866 12.186 0 0 0 P11172 UMPS_HUMAN Uridine 5'-monophosphate synthase (UMP synthase) [Includes: Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10); Orotidine 5'-phosphate decarboxylase (ODC) (OMPD) (EC 4.1.1.23) (OMPdecase)] UMPS OK/SW-cl.21 Homo sapiens (Human) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular response to xenobiotic stimulus [GO:0071466]; female pregnancy [GO:0007565]; lactation [GO:0007595]; pyrimidine nucleobase biosynthetic process [GO:0019856]; UDP biosynthetic process [GO:0006225]; UMP biosynthetic process [GO:0006222] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] identical protein binding [GO:0042802]; orotate phosphoribosyltransferase activity [GO:0004588]; orotidine-5'-phosphate decarboxylase activity [GO:0004590] 0.92576 -1.2101 ELSFGAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.27768 0 0 P11182 ODB2_HUMAN "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (EC 2.3.1.168) (52 kDa mitochondrial autoantigen of primary biliary cirrhosis) (Branched chain 2-oxo-acid dehydrogenase complex component E2) (BCOADC-E2) (Branched-chain alpha-keto acid dehydrogenase complex component E2) (BCKAD-E2) (BCKADE2) (Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex) (Dihydrolipoamide branched chain transacylase) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase)" DBT BCATE2 Homo sapiens (Human) branched-chain amino acid catabolic process [GO:0009083] cytoplasm [GO:0005737]; cytosol [GO:0005829]; microtubule cytoskeleton [GO:0015630]; mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739] acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625] 0.88799 -0.4006 LSDIGEGIR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.81471 0 0 0 0 0 0 0 0 0 0 13.6048 0 0 P11216 PYGB_HUMAN "Glycogen phosphorylase, brain form (EC 2.4.1.1)" PYGB Homo sapiens (Human) glycogen catabolic process [GO:0005980] azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020] glycogen phosphorylase activity [GO:0008184]; linear malto-oligosaccharide phosphorylase activity [GO:0102250]; pyridoxal phosphate binding [GO:0030170]; SHG alpha-glucan phosphorylase activity [GO:0102499] 0.0079156 2.0557 GLAGLGDVAEVR 0 0 0 0 0 0 0 0 0 9.70396 0 0 0 0 0 0 0 0 0 0 11.3653 10.269 0 0 11.2055 10.3032 10.6637 P11217 PYGM_HUMAN "Glycogen phosphorylase, muscle form (EC 2.4.1.1) (Myophosphorylase)" PYGM Homo sapiens (Human) glycogen catabolic process [GO:0005980]; glycogen metabolic process [GO:0005977] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062] glycogen phosphorylase activity [GO:0008184]; linear malto-oligosaccharide phosphorylase activity [GO:0102250]; nucleotide binding [GO:0000166]; pyridoxal phosphate binding [GO:0030170]; SHG alpha-glucan phosphorylase activity [GO:0102499] 0.78551 0.25925 ISGGWQMEEADDWLR 9.18259 0 9.88807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P11226 MBL2_HUMAN Mannose-binding protein C (MBP-C) (Collectin-1) (MBP1) (Mannan-binding protein) (Mannose-binding lectin) MBL2 COLEC1 MBL Homo sapiens (Human) "acute-phase response [GO:0006953]; antiviral innate immune response [GO:0140374]; cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; killing by host of symbiont cells [GO:0051873]; negative regulation of viral process [GO:0048525]; opsonization [GO:0008228]; positive regulation of opsonization [GO:1903028]; positive regulation of phagocytosis [GO:0050766]; proteolysis [GO:0006508]; response to oxidative stress [GO:0006979]; surfactant homeostasis [GO:0043129]" cell surface [GO:0009986]; collagen trimer [GO:0005581]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; serine-type endopeptidase complex [GO:1905370] calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; signaling receptor binding [GO:0005102] 0.86867 0.071794 FFLTNGEIMTFEK 0 0 0 0 0 12.9347 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P11234 RALB_HUMAN Ras-related protein Ral-B (EC 3.6.5.2) RALB Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to exogenous dsRNA [GO:0071360]; cellular response to starvation [GO:0009267]; negative regulation of protein binding [GO:0032091]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of protein binding [GO:0032092]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of exocyst assembly [GO:0001928]; regulation of exocyst localization [GO:0060178]; signal transduction [GO:0007165] extracellular exosome [GO:0070062]; midbody [GO:0030496]; plasma membrane [GO:0005886] ATPase binding [GO:0051117]; G protein activity [GO:0003925]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ubiquitin protein ligase binding [GO:0031625] 0.96252 -2.5369 EQILRVKAEEDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.37458 0 0 0 0 0 0 0 0 0 10.2881 0 0 P11245 ARY2_HUMAN Arylamine N-acetyltransferase 2 (EC 2.3.1.5) (Arylamide acetylase 2) (N-acetyltransferase type 2) (NAT-2) (Polymorphic arylamine N-acetyltransferase) (PNAT) NAT2 AAC2 Homo sapiens (Human) xenobiotic metabolic process [GO:0006805] cytosol [GO:0005829] arylamine N-acetyltransferase activity [GO:0004060] 0.88362 -0.27861 EFLNSHLLPK 9.0655 8.98937 8.83719 0 0 0 0 0 0 9.53347 10.8599 10.2384 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P11274 BCR_HUMAN Breakpoint cluster region protein (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-26) BCR BCR1 D22S11 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; activation of GTPase activity [GO:0090630]; brain development [GO:0007420]; cellular response to lipopolysaccharide [GO:0071222]; definitive hemopoiesis [GO:0060216]; focal adhesion assembly [GO:0048041]; homeostasis of number of cells [GO:0048872]; inner ear morphogenesis [GO:0042472]; intracellular protein transmembrane transport [GO:0065002]; keratinocyte differentiation [GO:0030216]; macrophage migration [GO:1905517]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of blood vessel remodeling [GO:0060313]; negative regulation of cellular extravasation [GO:0002692]; negative regulation of inflammatory response [GO:0050728]; negative regulation of macrophage migration [GO:1905522]; negative regulation of neutrophil degranulation [GO:0043314]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of respiratory burst [GO:0060268]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; positive regulation of phagocytosis [GO:0050766]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of nitrogen compound metabolic process [GO:0051171]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of vascular permeability [GO:0043114]; renal system process [GO:0003014]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264] axon [GO:0030424]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685] ATP binding [GO:0005524]; GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713] 0.90553 -0.72885 ISQNFLSSINEEITPR 0 0 8.38098 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.75394 0 0 0 0 0 0 0 0 P11277 SPTB1_HUMAN "Spectrin beta chain, erythrocytic (Beta-I spectrin)" SPTB SPTB1 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament capping [GO:0051693]; modification of postsynaptic actin cytoskeleton [GO:0098885] actin cytoskeleton [GO:0015629]; cell junction [GO:0030054]; cell projection [GO:0042995]; cell surface [GO:0009986]; cortical actin cytoskeleton [GO:0030864]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]; spectrin [GO:0008091]; spectrin-associated cytoskeleton [GO:0014731] actin binding [GO:0003779]; actin filament binding [GO:0051015]; ankyrin binding [GO:0030506]; structural constituent of cytoskeleton [GO:0005200] 0.964 -2.2776 ALEDLAQELEKENYHDQK 0 0 0 0 10.3472 0 0 0 0 0 0 0 0 0 0 8.70808 11.0667 0 0 0 0 0 0 0 9.05897 11.7962 9.9479 P11279 LAMP1_HUMAN Lysosome-associated membrane glycoprotein 1 (LAMP-1) (Lysosome-associated membrane protein 1) (CD107 antigen-like family member A) (CD antigen CD107a) LAMP1 Homo sapiens (Human) establishment of protein localization to organelle [GO:0072594]; Golgi to lysosome transport [GO:0090160]; granzyme-mediated programmed cell death signaling pathway [GO:0140507]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; protein stabilization [GO:0050821]; regulation of organelle transport along microtubule [GO:1902513] autolysosome [GO:0044754]; autophagosome membrane [GO:0000421]; azurophil granule membrane [GO:0035577]; cytolytic granule membrane [GO:0101004]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane [GO:0016020]; multivesicular body [GO:0005771]; perinuclear region of cytoplasm [GO:0048471]; phagolysosome membrane [GO:0061474]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; synaptic vesicle [GO:0008021] enzyme binding [GO:0019899]; protein domain specific binding [GO:0019904]; virus receptor activity [GO:0001618] 0.55932 0.54648 TVESITDIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.76822 10.7995 9.90352 0 0 P11310 ACADM_HUMAN "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (MCAD) (EC 1.3.8.7) (Medium chain acyl-CoA dehydrogenase) (MCADH)" ACADM Homo sapiens (Human) "cardiac muscle cell differentiation [GO:0055007]; carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; glycogen biosynthetic process [GO:0005978]; liver development [GO:0001889]; medium-chain fatty acid catabolic process [GO:0051793]; medium-chain fatty acid metabolic process [GO:0051791]; post-embryonic development [GO:0009791]; regulation of gluconeogenesis [GO:0006111]; response to cold [GO:0009409]; response to starvation [GO:0042594]" axon [GO:0030424]; cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634] acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991] 0.96785 -3.7363 SISRFHWR 0 0 0 0 0 0 0 0 9.35645 0 0 0 0 0 0 0 0 0 0 0 11.0143 0 0 0 10.241 0 9.75882 P11362 FGFR1_HUMAN Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331) FGFR1 BFGFR CEK FGFBR FLG FLT2 HBGFR Homo sapiens (Human) cell migration [GO:0016477]; chordate embryonic development [GO:0043009]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; neuron migration [GO:0001764]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell differentiation [GO:0045595]; regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001239]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; receptor-receptor interaction [GO:0090722] 0.86433 0.079375 TVALGSNVEFMCK 0 0 9.41981 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P11387 TOP1_HUMAN DNA topoisomerase 1 (EC 5.6.2.1) (DNA topoisomerase I) TOP1 Homo sapiens (Human) chromatin remodeling [GO:0006338]; chromosome segregation [GO:0007059]; circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; DNA replication [GO:0006260]; DNA topological change [GO:0006265]; embryonic cleavage [GO:0040016]; peptidyl-serine phosphorylation [GO:0018105]; phosphorylation [GO:0016310]; programmed cell death [GO:0012501]; response to xenobiotic stimulus [GO:0009410] chromosome [GO:0005694]; fibrillar center [GO:0001650]; male germ cell nucleus [GO:0001673]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; perikaryon [GO:0043204]; protein-DNA complex [GO:0032993] "ATP binding [GO:0005524]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA binding, bending [GO:0008301]; DNA topoisomerase type I (single strand cut, ATP-independent) activity [GO:0003917]; double-stranded DNA binding [GO:0003690]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; RNA binding [GO:0003723]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; single-stranded DNA binding [GO:0003697]; supercoiled DNA binding [GO:0097100]" 0.88394 -0.14442 AQTEARKQMSK 0 0 0 0 0 0 0 0 0 0 0 11.8406 0 0 0 0 0 0 0 0 9.48657 0 0 0 0 8.76052 9.81126 P11388 TOP2A_HUMAN "DNA topoisomerase 2-alpha (EC 5.6.2.2) (DNA topoisomerase II, alpha isozyme)" TOP2A TOP2 Homo sapiens (Human) apoptotic chromosome condensation [GO:0030263]; chromosome segregation [GO:0007059]; DNA damage response [GO:0006974]; DNA ligation [GO:0006266]; DNA topological change [GO:0006265]; embryonic cleavage [GO:0040016]; female meiotic nuclear division [GO:0007143]; hematopoietic progenitor cell differentiation [GO:0002244]; negative regulation of DNA duplex unwinding [GO:1905463]; positive regulation of apoptotic process [GO:0043065]; positive regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045870]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of circadian rhythm [GO:0042752]; resolution of meiotic recombination intermediates [GO:0000712]; rhythmic process [GO:0048511]; sister chromatid segregation [GO:0000819] "chromosome, centromeric region [GO:0000775]; condensed chromosome [GO:0000793]; cytoplasm [GO:0005737]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex [GO:0009330]; male germ cell nucleus [GO:0001673]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]" "ATP binding [GO:0005524]; ATP-dependent activity, acting on DNA [GO:0008094]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA binding, bending [GO:0008301]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase C binding [GO:0005080]; RNA binding [GO:0003723]; ubiquitin binding [GO:0043130]" 0.95743 -1.6559 FTVETASREYK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7881 0 9.57637 11.1137 9.15292 10.9596 0 0 0 0 0 10.9672 0 0 P11413 G6PD_HUMAN Glucose-6-phosphate 1-dehydrogenase (G6PD) (EC 1.1.1.49) G6PD Homo sapiens (Human) "cellular response to oxidative stress [GO:0034599]; cholesterol biosynthetic process [GO:0006695]; erythrocyte maturation [GO:0043249]; glucose 6-phosphate metabolic process [GO:0051156]; glucose metabolic process [GO:0006006]; glutathione metabolic process [GO:0006749]; lipid metabolic process [GO:0006629]; NADP metabolic process [GO:0006739]; NADPH regeneration [GO:0006740]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; negative regulation of protein glutathionylation [GO:0010734]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; pentose biosynthetic process [GO:0019322]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]; positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1904879]; regulation of neuron apoptotic process [GO:0043523]; response to ethanol [GO:0045471]; response to food [GO:0032094]; response to iron(III) ion [GO:0010041]; response to organic cyclic compound [GO:0014070]; ribose phosphate biosynthetic process [GO:0046390]; substantia nigra development [GO:0021762]" centriolar satellite [GO:0034451]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleus [GO:0005634] glucose binding [GO:0005536]; glucose-6-phosphate dehydrogenase activity [GO:0004345]; identical protein binding [GO:0042802]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803] 0.096045 1.1887 AEQVALSR 0 0 11.2019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.33418 0 0 0 0 0 0 P11487 FGF3_HUMAN Fibroblast growth factor 3 (FGF-3) (Heparin-binding growth factor 3) (HBGF-3) (Proto-oncogene Int-2) FGF3 INT2 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; animal organ morphogenesis [GO:0009887]; cell differentiation [GO:0030154]; cell-cell signaling [GO:0007267]; fibroblast growth factor receptor signaling pathway [GO:0008543]; negative regulation of cardiac muscle tissue development [GO:0055026]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of protein phosphorylation [GO:0001934]; regulation of cell migration [GO:0030334]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615] fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083] 0.91228 -0.74964 SSLFLPRVLDHR 0 0 0 0 0 0 0 0 12.6347 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P11498 PYC_HUMAN "Pyruvate carboxylase, mitochondrial (EC 6.4.1.1) (Pyruvic carboxylase) (PCB)" PC Homo sapiens (Human) gluconeogenesis [GO:0006094]; lipid metabolic process [GO:0006629]; NADH metabolic process [GO:0006734]; NADP metabolic process [GO:0006739]; negative regulation of gene expression [GO:0010629]; positive regulation by host of viral process [GO:0044794]; pyruvate metabolic process [GO:0006090]; viral release from host cell [GO:0019076]; viral RNA genome packaging [GO:0019074] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; biotin binding [GO:0009374]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; pyruvate carboxylase activity [GO:0004736] 0.88261 -0.26781 ADEAYLIGR 0 0 0 0 0 0 0 0 9.1171 0 0 0 0 10.3253 10.2709 10.2131 0 12.1406 10.9449 9.17318 0 9.30221 0 0 10.4723 10.9243 8.78018 P11509 CP2A6_HUMAN "Cytochrome P450 2A6 (EC 1.14.14.-) (1,4-cineole 2-exo-monooxygenase) (CYPIIA6) (Coumarin 7-hydroxylase) (Cytochrome P450 IIA3) (Cytochrome P450(I))" CYP2A6 CYP2A3 Homo sapiens (Human) coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; steroid metabolic process [GO:0008202]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805] cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231] "arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]" 0.91551 -0.80611 TVSNVISSIVFGDRFDYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7122 0 0 0 0 0 P11511 CP19A_HUMAN Aromatase (EC 1.14.14.14) (CYPXIX) (Cytochrome P-450AROM) (Cytochrome P450 19A1) (Estrogen synthase) CYP19A1 ARO1 CYAR CYP19 Homo sapiens (Human) androgen catabolic process [GO:0006710]; estrogen biosynthetic process [GO:0006703]; female genitalia development [GO:0030540]; female gonad development [GO:0008585]; mammary gland development [GO:0030879]; negative regulation of chronic inflammatory response [GO:0002677]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of estradiol secretion [GO:2000866]; prostate gland growth [GO:0060736]; steroid biosynthetic process [GO:0006694]; sterol metabolic process [GO:0016125]; syncytium formation [GO:0006949]; testosterone biosynthetic process [GO:0061370]; uterus development [GO:0060065] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] "aromatase activity [GO:0070330]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; oxygen binding [GO:0019825]; steroid hydroxylase activity [GO:0008395]" 0.58926 0.45957 ALEDDVIDGYPVK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1202 0 0 0 0 0 0 0 0 0 0 0 0 0 P11532 DMD_HUMAN Dystrophin DMD Homo sapiens (Human) cardiac muscle cell action potential [GO:0086001]; cardiac muscle contraction [GO:0060048]; maintenance of blood-brain barrier [GO:0035633]; motile cilium assembly [GO:0044458]; muscle cell cellular homeostasis [GO:0046716]; muscle cell development [GO:0055001]; muscle organ development [GO:0007517]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; neuron development [GO:0048666]; peptide biosynthetic process [GO:0043043]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; protein localization [GO:0008104]; protein-containing complex assembly [GO:0065003]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cellular response to growth factor stimulus [GO:0090287]; regulation of heart rate [GO:0002027]; regulation of muscle system process [GO:0090257]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of skeletal muscle contraction [GO:0014819]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to muscle stretch [GO:0035994]; skeletal muscle tissue development [GO:0007519]; synaptic signaling [GO:0099536] cell surface [GO:0009986]; cell-substrate junction [GO:0030055]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dystrophin-associated glycoprotein complex [GO:0016010]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; membrane raft [GO:0045121]; neuron projection terminus [GO:0044306]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]; syntrophin complex [GO:0016013]; Z disc [GO:0030018] actin binding [GO:0003779]; dystroglycan binding [GO:0002162]; myosin binding [GO:0017022]; nitric-oxide synthase binding [GO:0050998]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; vinculin binding [GO:0017166]; zinc ion binding [GO:0008270] 0.96856 -3.849 AVEEMKRAK 0 0 0 0 0 0 0 0 0 11.7727 0 0 0 10.1003 0 10.6544 0 10.1597 9.1603 0 0 0 0 0 10.758 0 0 P11586 C1TC_HUMAN "C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF synthase) (Epididymis secretory sperm binding protein) [Cleaved into: C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed] [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)]" MTHFD1 MTHFC MTHFD Homo sapiens (Human) 10-formyltetrahydrofolate biosynthetic process [GO:0009257]; embryonic neurocranium morphogenesis [GO:0048702]; embryonic viscerocranium morphogenesis [GO:0048703]; heart development [GO:0007507]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]; neural tube closure [GO:0001843]; neutrophil homeostasis [GO:0001780]; one-carbon metabolic process [GO:0006730]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleotide biosynthetic process [GO:0009152]; serine family amino acid biosynthetic process [GO:0009070]; serine family amino acid metabolic process [GO:0009069]; somite development [GO:0061053]; tetrahydrofolate interconversion [GO:0035999]; transsulfuration [GO:0019346] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; formate-tetrahydrofolate ligase activity [GO:0004329]; methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NAD+) activity [GO:0004487]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity [GO:0004486] 0.92398 -1.0221 EQVPGFTPR 10.5514 9.36448 9.40037 11.1583 11.9989 11.4922 10.4292 9.46799 9.71051 12.604 11.257 13.2925 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.66441 P11597 CETP_HUMAN Cholesteryl ester transfer protein (Lipid transfer protein I) CETP Homo sapiens (Human) cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; high-density lipoprotein particle remodeling [GO:0034375]; lipid homeostasis [GO:0055088]; lipid transport [GO:0006869]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; phosphatidylcholine metabolic process [GO:0046470]; phospholipid homeostasis [GO:0055091]; positive regulation of cholesterol transport [GO:0032376]; positive regulation of phospholipid transport [GO:2001140]; regulation of cholesterol efflux [GO:0010874]; reverse cholesterol transport [GO:0043691]; triglyceride homeostasis [GO:0070328]; triglyceride metabolic process [GO:0006641]; triglyceride transport [GO:0034197]; very-low-density lipoprotein particle remodeling [GO:0034372] extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; high-density lipoprotein particle [GO:0034364]; vesicle [GO:0031982] cholesterol binding [GO:0015485]; cholesterol transfer activity [GO:0120020]; lipid binding [GO:0008289]; phosphatidylcholine binding [GO:0031210]; phospholipid transporter activity [GO:0005548]; triglyceride binding [GO:0017129] 0.90632 -0.72551 ISCQNKGVVVNSSVMVK 0 0 9.50454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P11678 PERE_HUMAN Eosinophil peroxidase (EPO) (EC 1.11.1.7) [Cleaved into: Eosinophil peroxidase light chain; Eosinophil peroxidase heavy chain] EPX EPER EPO EPP Homo sapiens (Human) defense response to bacterium [GO:0042742]; defense response to nematode [GO:0002215]; eosinophil migration [GO:0072677]; hydrogen peroxide catabolic process [GO:0042744]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of interleukin-5 production [GO:0032714]; negative regulation of macrophage cytokine production [GO:0010936]; positive regulation of interleukin-4 production [GO:0032753]; response to oxidative stress [GO:0006979] extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule lumen [GO:0034774] heme binding [GO:0020037]; lactoperoxidase activity [GO:0140825]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601] 0.96272 -2.6304 GFVNCSRIPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5469 0 0 0 0 0 10.4411 P11717 MPRI_HUMAN Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222) IGF2R MPRI Homo sapiens (Human) animal organ regeneration [GO:0031100]; G protein-coupled receptor signaling pathway [GO:0007186]; liver development [GO:0001889]; lysosomal transport [GO:0007041]; positive regulation by host of viral process [GO:0044794]; positive regulation of apoptotic process [GO:0043065]; post-embryonic development [GO:0009791]; receptor-mediated endocytosis [GO:0006898]; response to retinoic acid [GO:0032526]; response to tetrachloromethane [GO:1904772]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283] cell surface [GO:0009986]; clathrin coat [GO:0030118]; clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; late endosome [GO:0005770]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588]; trans-Golgi network transport vesicle [GO:0030140]; transport vesicle [GO:0030133] enzyme binding [GO:0019899]; G-protein alpha-subunit binding [GO:0001965]; identical protein binding [GO:0042802]; insulin-like growth factor binding [GO:0005520]; insulin-like growth factor II binding [GO:0031995]; insulin-like growth factor receptor activity [GO:0005010]; mannose binding [GO:0005537]; phosphoprotein binding [GO:0051219]; retinoic acid binding [GO:0001972]; retromer complex binding [GO:1905394]; signaling receptor activity [GO:0038023] 0.96945 -3.5514 FLHQDIDSGQGIR 0 0 9.12156 0 0 0 0 0 0 0 0 10.0447 0 0 0 0 0 11.0307 9.30417 0 0 0 0 10.4843 0 0 8.72431 P11908 PRPS2_HUMAN Ribose-phosphate pyrophosphokinase 2 (EC 2.7.6.1) (PPRibP) (Phosphoribosyl pyrophosphate synthase II) (PRS-II) PRPS2 Homo sapiens (Human) 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; AMP biosynthetic process [GO:0006167]; animal organ regeneration [GO:0031100]; nucleobase-containing compound metabolic process [GO:0006139]; pentose-phosphate shunt [GO:0006098]; phosphorylation [GO:0016310]; purine nucleotide biosynthetic process [GO:0006164] cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribose phosphate diphosphokinase complex [GO:0002189] ADP binding [GO:0043531]; AMP binding [GO:0016208]; ATP binding [GO:0005524]; carbohydrate binding [GO:0030246]; GDP binding [GO:0019003]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; ribose phosphate diphosphokinase activity [GO:0004749] 0.55852 0.53074 MPNIVLFSGSSHQDLSQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7062 0 0 0 0 11.0653 0 0 0 0 0 0 P11926 DCOR_HUMAN Ornithine decarboxylase (ODC) (EC 4.1.1.17) ODC1 Homo sapiens (Human) cell population proliferation [GO:0008283]; kidney development [GO:0001822]; polyamine metabolic process [GO:0006595]; positive regulation of cell population proliferation [GO:0008284]; putrescine biosynthetic process from ornithine [GO:0033387]; regulation of protein catabolic process [GO:0042176]; response to virus [GO:0009615] cytoplasm [GO:0005737]; cytosol [GO:0005829] ornithine decarboxylase activity [GO:0004586]; protein homodimerization activity [GO:0042803] 0.91393 -0.79891 IIYANPCKQVSQIK 0 0 12.1124 0 0 0 0 13.263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P11940 PABP1_HUMAN Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1) PABPC1 PAB1 PABP PABP1 PABPC2 Homo sapiens (Human) "CRD-mediated mRNA stabilization [GO:0070934]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; RNA-mediated gene silencing [GO:0031047]" catalytic step 2 spliceosome [GO:0071013]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; mCRD-mediated mRNA stability complex [GO:0106002]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; translation activator activity [GO:0008494] 0 5.8574 ALDTMNFDVIK 0 0 0 0 0 0 9.40352 10.0916 0 0 9.15066 0 0 0 0 0 0 0 0 0 9.32308 0 0 9.23489 0 10.3604 10.1012 P12004 PCNA_HUMAN Proliferating cell nuclear antigen (PCNA) (Cyclin) PCNA Homo sapiens (Human) "base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; epithelial cell differentiation [GO:0030855]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; translesion synthesis [GO:0019985]" "centrosome [GO:0005813]; chromatin [GO:0000785]; chromosome, telomeric region [GO:0000781]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; male germ cell nucleus [GO:0001673]; nuclear body [GO:0016604]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]" chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; nuclear estrogen receptor binding [GO:0030331]; protein-containing complex binding [GO:0044877]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971] 0 7.241 AEDNADTLALVFEAPNQEK 0 0 9.13935 0 0 0 0 0 0 0 0 0 0 0 0 10.4166 9.46673 0 0 0 0 0 0 0 0 0 0 P12035 K2C3_HUMAN "Keratin, type II cytoskeletal 3 (65 kDa cytokeratin) (Cytokeratin-3) (CK-3) (Keratin-3) (K3) (Type-II keratin Kb3)" KRT3 Homo sapiens (Human) epithelial cell differentiation [GO:0030855]; intermediate filament cytoskeleton organization [GO:0045104]; keratinization [GO:0031424] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; keratin filament [GO:0045095] structural constituent of skin epidermis [GO:0030280] 0.73286 0.33001 DYQELMNVK 0 0 0 0 0 0 0 0 0 0 9.3295 0 0 0 0 0 0 0 8.97117 0 0 0 0 0 0 0 0 P12036 NFH_HUMAN Neurofilament heavy polypeptide (NF-H) (200 kDa neurofilament protein) (Neurofilament triplet H protein) NEFH KIAA0845 NFH Homo sapiens (Human) axon development [GO:0061564]; axonogenesis [GO:0007409]; cell projection assembly [GO:0030031]; cellular response to leukemia inhibitory factor [GO:1990830]; microtubule cytoskeleton organization [GO:0000226]; neurofilament bundle assembly [GO:0033693]; neurofilament cytoskeleton organization [GO:0060052]; peripheral nervous system neuron axonogenesis [GO:0048936]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of organelle transport along microtubule [GO:1902513] axon [GO:0030424]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; neurofibrillary tangle [GO:0097418]; neurofilament [GO:0005883]; postsynaptic density [GO:0014069]; postsynaptic intermediate filament cytoskeleton [GO:0099160]; Schaffer collateral - CA1 synapse [GO:0098685] dynein complex binding [GO:0070840]; kinesin binding [GO:0019894]; microtubule binding [GO:0008017]; protein kinase binding [GO:0019901]; protein-macromolecule adaptor activity [GO:0030674]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of postsynaptic intermediate filament cytoskeleton [GO:0099184] 0.96946 -3.9662 AKKPEEKPKTEAK 10.3132 0 0 11.6954 12.2156 12.3876 0 0 0 0 0 10.9969 0 11.1273 9.96519 0 0 9.3901 0 0 0 0 0 0 0 0 0 P12081 HARS1_HUMAN "Histidine--tRNA ligase, cytoplasmic (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS)" HARS1 HARS HRS Homo sapiens (Human) histidyl-tRNA aminoacylation [GO:0006427]; mitochondrial translation [GO:0032543]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803] 0.958 -1.6658 GLAPEVADR 0 0 0 0 9.8981 0 8.54763 8.7416 0 0 0 10.218 9.38185 9.64929 9.58293 10.1794 0 9.98712 11.0461 9.55461 0 9.22386 9.06196 9.2826 11.3431 10.168 10.9615 P12107 COBA1_HUMAN Collagen alpha-1(XI) chain COL11A1 COLL6 Homo sapiens (Human) cartilage condensation [GO:0001502]; chondrocyte development [GO:0002063]; collagen fibril organization [GO:0030199]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; embryonic skeletal system morphogenesis [GO:0048704]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; inner ear morphogenesis [GO:0042472]; ossification [GO:0001503]; proteoglycan metabolic process [GO:0006029]; sensory perception of sound [GO:0007605]; tendon development [GO:0035989]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; visual perception [GO:0007601] collagen type XI trimer [GO:0005592]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] extracellular matrix binding [GO:0050840]; extracellular matrix structural constituent [GO:0005201]; heparan sulfate binding [GO:1904399]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein-macromolecule adaptor activity [GO:0030674] 0.8842 -0.16086 GETGFQGK 0 0 0 0 8.02879 0 0 0 0 0 0 0 0 0 0 0 0 10.6827 9.46461 0 9.54709 0 10.0133 0 0 9.32085 0 P12109 CO6A1_HUMAN Collagen alpha-1(VI) chain COL6A1 Homo sapiens (Human) cell adhesion [GO:0007155]; cellular response to amino acid stimulus [GO:0071230]; endodermal cell differentiation [GO:0035987]; osteoblast differentiation [GO:0001649] collagen type VI trimer [GO:0005589]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383] collagen binding [GO:0005518]; extracellular matrix structural constituent conferring tensile strength [GO:0030020]; platelet-derived growth factor binding [GO:0048407] 0.952 -1.4285 SSVDAVKYFGKGTYTDCAIK 0 0 0 0 0 0 0 0 0 0 0 0 0 11.9328 0 0 0 0 0 0 0 0 0 0 0 0 0 P12110 CO6A2_HUMAN Collagen alpha-2(VI) chain COL6A2 Homo sapiens (Human) cell adhesion [GO:0007155]; response to glucose [GO:0009749] collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383] collagen binding [GO:0005518]; extracellular matrix structural constituent conferring tensile strength [GO:0030020] 0.96197 -2.4657 GLAGEVGNKGAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.09418 0 0 P12111 CO6A3_HUMAN Collagen alpha-3(VI) chain COL6A3 Homo sapiens (Human) cell adhesion [GO:0007155]; muscle organ development [GO:0007517]; negative regulation of peptidase activity [GO:0010466] collagen type VI trimer [GO:0005589]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; sarcolemma [GO:0042383] extracellular matrix structural constituent conferring tensile strength [GO:0030020]; serine-type endopeptidase inhibitor activity [GO:0004867] 0.10319 1.1689 IASNSATAFR 0 0 0 0 0 0 0 0 10.4038 0 0 0 9.13802 0 8.97042 0 0 0 0 12.106 0 0 0 0 10.0542 0 0 P12236 ADT3_HUMAN "ADP/ATP translocase 3 (ADP,ATP carrier protein 3) (ADP,ATP carrier protein, isoform T2) (ANT 2) (Adenine nucleotide translocator 3) (ANT 3) (Solute carrier family 25 member 6) [Cleaved into: ADP/ATP translocase 3, N-terminally processed]" SLC25A6 AAC3 ANT3 CDABP0051 Homo sapiens (Human) apoptotic process [GO:0006915]; mitochondrial ADP transmembrane transport [GO:0140021]; mitochondrial ATP transmembrane transport [GO:1990544]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029] membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; TIM23 mitochondrial import inner membrane translocase complex [GO:0005744] ATP:ADP antiporter activity [GO:0005471] 0.01005 1.8872 AAYFGVYDTAK 0 0 0 0 0 0 8.66416 8.95251 0 10.9403 0 10.4902 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P12259 FA5_HUMAN "Coagulation factor V (Activated protein C cofactor) (Proaccelerin, labile factor) [Cleaved into: Coagulation factor V heavy chain; Coagulation factor V light chain]" F5 Homo sapiens (Human) "blood circulation [GO:0008015]; blood coagulation [GO:0007596]; blood coagulation, common pathway [GO:0072377]; blood coagulation, extrinsic pathway [GO:0007598]; proteolysis [GO:0006508]; response to vitamin K [GO:0032571]; zymogen activation [GO:0031638]" COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; serine-type endopeptidase complex [GO:1905370] copper ion binding [GO:0005507] 0.94854 -1.3613 EFVLLFMTFDEKKSWYYEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.82831 0 0 0 0 0 0 0 0 0 P12270 TPR_HUMAN Nucleoprotein TPR (Megator) (NPC-associated intranuclear protein) (Translocated promoter region protein) TPR Homo sapiens (Human) cell division [GO:0051301]; cellular response to heat [GO:0034605]; cellular response to interferon-alpha [GO:0035457]; mitotic spindle assembly checkpoint signaling [GO:0007094]; mRNA export from nucleus [GO:0006406]; mRNA export from nucleus in response to heat stress [GO:0031990]; negative regulation of RNA export from nucleus [GO:0046832]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of translational initiation [GO:0045947]; nuclear pore organization [GO:0006999]; nucleocytoplasmic transport [GO:0006913]; positive regulation of heterochromatin formation [GO:0031453]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein import into nucleus [GO:0042307]; protein import into nucleus [GO:0006606]; regulation of mitotic sister chromatid separation [GO:0010965]; regulation of mitotic spindle assembly [GO:1901673]; regulation of protein localization [GO:0032880]; response to epidermal growth factor [GO:0070849]; RNA export from nucleus [GO:0006405]; RNA import into nucleus [GO:0006404] cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; extrinsic component of membrane [GO:0019898]; kinetochore [GO:0000776]; mitotic spindle [GO:0072686]; nuclear envelope [GO:0005635]; nuclear inclusion body [GO:0042405]; nuclear membrane [GO:0031965]; nuclear periphery [GO:0034399]; nuclear pore [GO:0005643]; nuclear pore nuclear basket [GO:0044615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; dynein complex binding [GO:0070840]; heat shock protein binding [GO:0031072]; mitogen-activated protein kinase binding [GO:0051019]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; structural constituent of nuclear pore [GO:0017056]; tubulin binding [GO:0015631] 0.9688 -11.596 DPDTEEYRK 14.5244 0 0 10.9851 10.6667 9.98071 11.2878 0 0 9.39433 0 0 0 0 0 10.4711 0 0 9.17443 0 0 0 0 0 0 0 10.2596 P12271 RLBP1_HUMAN Retinaldehyde-binding protein 1 (Cellular retinaldehyde-binding protein) RLBP1 CRALBP Homo sapiens (Human) response to stimulus [GO:0050896]; visual perception [GO:0007601]; vitamin A metabolic process [GO:0006776] cell body [GO:0044297]; centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654] 11-cis retinal binding [GO:0005502]; phosphatidylinositol bisphosphate binding [GO:1902936]; retinol binding [GO:0019841] 0.88249 -0.30027 DELNEREETR 0 8.65481 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P12272 PTHR_HUMAN Parathyroid hormone-related protein (PTH-rP) (PTHrP) (Parathyroid hormone-like protein) (PLP) [Cleaved into: PTHrP[1-36]; PTHrP[38-94]; Osteostatin (PTHrP[107-139])] PTHLH PTHRP Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; bone mineralization [GO:0030282]; cAMP metabolic process [GO:0046058]; cell-cell signaling [GO:0007267]; epidermis development [GO:0008544]; female pregnancy [GO:0007565]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chondrocyte development [GO:0061182]; negative regulation of chondrocyte differentiation [GO:0032331]; osteoblast development [GO:0002076]; positive regulation of cell population proliferation [GO:0008284]; regulation of chondrocyte differentiation [GO:0032330]; regulation of gene expression [GO:0010468]; skeletal system development [GO:0001501] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654] hormone activity [GO:0005179]; peptide hormone receptor binding [GO:0051428] 0.89984 -0.61079 GKSIQDLRR 0 0 0 0 0 0 0 12.5302 0 0 0 0 0 9.56982 0 0 0 0 0 0 11.0673 0 0 0 0 0 0 P12277 KCRB_HUMAN Creatine kinase B-type (EC 2.7.3.2) (Brain creatine kinase) (B-CK) (Creatine kinase B chain) (Creatine phosphokinase B-type) (CPK-B) CKB CKBB Homo sapiens (Human) cellular response to estrogen stimulus [GO:0071391]; cellular response to wortmannin [GO:1904568]; cerebellum development [GO:0021549]; futile creatine cycle [GO:0140651]; intracellular chloride ion homeostasis [GO:0030644]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]; substantia nigra development [GO:0021762] cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; ubiquitin protein ligase binding [GO:0031625] 0 10.372 DLFDPIIEDR 0 0 9.73944 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.062 11.6479 9.89002 P12318 FCG2A_HUMAN Low affinity immunoglobulin gamma Fc region receptor II-a (IgG Fc receptor II-a) (CDw32) (Fc-gamma RII-a) (Fc-gamma-RIIa) (FcRII-a) (CD antigen CD32) FCGR2A CD32 FCG2 FCGR2A1 IGFR2 Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; immune system process [GO:0002376] Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667] IgG binding [GO:0019864]; transmembrane signaling receptor activity [GO:0004888] 0.90605 -0.72814 ISANSTDPVK 0 9.09463 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P12429 ANXA3_HUMAN "Annexin A3 (35-alpha calcimedin) (Annexin III) (Annexin-3) (Inositol 1,2-cyclic phosphate 2-phosphohydrolase) (Lipocortin III) (Placental anticoagulant protein III) (PAP-III)" ANXA3 ANX3 Homo sapiens (Human) animal organ regeneration [GO:0031100]; defense response to bacterium [GO:0042742]; hippocampus development [GO:0021766]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; positive regulation of angiogenesis [GO:0045766]; positive regulation of DNA metabolic process [GO:0051054]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelial cell migration [GO:0010595]; response to glucocorticoid [GO:0051384]; response to growth factor [GO:0070848] axon [GO:0030424]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; specific granule [GO:0042581] calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; phospholipase A2 inhibitor activity [GO:0019834] 0 5.7437 GIGTDEFTLNR 9.15507 10.2486 9.14062 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.14621 0 0 0 P12532 KCRU_HUMAN "Creatine kinase U-type, mitochondrial (EC 2.7.3.2) (Acidic-type mitochondrial creatine kinase) (Mia-CK) (Ubiquitous mitochondrial creatine kinase) (U-MtCK)" CKMT1A CKMT; CKMT1B CKMT Homo sapiens (Human) phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; creatine kinase activity [GO:0004111] 0.21912 0.88478 AGVHIKLPLLSKDSR 0 0 0 0 0 0 0 0 0 9.76906 0 9.70254 0 10.1513 0 0 0 9.38074 0 0 9.02409 0 0 0 0 10.8305 9.68822 P12644 BMP4_HUMAN Bone morphogenetic protein 4 (BMP-4) (Bone morphogenetic protein 2B) (BMP-2B) BMP4 BMP2B DVR4 Homo sapiens (Human) ameloblast differentiation [GO:0036305]; anterior/posterior axis specification [GO:0009948]; aortic valve morphogenesis [GO:0003180]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; BMP signaling pathway [GO:0030509]; BMP signaling pathway involved in heart development [GO:0061312]; BMP signaling pathway involved in heart induction [GO:0003130]; BMP signaling pathway involved in nephric duct formation [GO:0071893]; BMP signaling pathway involved in renal system segmentation [GO:0061151]; BMP signaling pathway involved in ureter morphogenesis [GO:0061149]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; branching morphogenesis of an epithelial tube [GO:0048754]; bronchus development [GO:0060433]; bud dilation involved in lung branching [GO:0060503]; bud elongation involved in lung branching [GO:0060449]; cardiac muscle cell differentiation [GO:0055007]; cardiac septum development [GO:0003279]; cellular response to BMP stimulus [GO:0071773]; chondrocyte differentiation [GO:0002062]; cloacal septation [GO:0060197]; common-partner SMAD protein phosphorylation [GO:0007182]; coronary vasculature development [GO:0060976]; cranial suture morphogenesis [GO:0060363]; deltoid tuberosity development [GO:0035993]; dorsal/ventral neural tube patterning [GO:0021904]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digit morphogenesis [GO:0042733]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic skeletal joint morphogenesis [GO:0060272]; endocardial cushion development [GO:0003197]; endochondral ossification [GO:0001958]; endoderm development [GO:0007492]; epithelial cell proliferation involved in lung morphogenesis [GO:0060502]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; epithelial-mesenchymal cell signaling [GO:0060684]; erythrocyte differentiation [GO:0030218]; germ cell development [GO:0007281]; glomerular capillary formation [GO:0072104]; hematopoietic progenitor cell differentiation [GO:0002244]; inner ear auditory receptor cell differentiation [GO:0042491]; intermediate mesodermal cell differentiation [GO:0048392]; kidney development [GO:0001822]; lens induction in camera-type eye [GO:0060235]; lung alveolus development [GO:0048286]; lung morphogenesis [GO:0060425]; lymphoid progenitor cell differentiation [GO:0002320]; macrophage differentiation [GO:0030225]; mammary gland formation [GO:0060592]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation involved in kidney development [GO:0072161]; mesenchymal cell proliferation involved in ureter development [GO:0072198]; mesenchymal cell proliferation involved in ureteric bud development [GO:0072138]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; mesodermal cell fate determination [GO:0007500]; mesonephros development [GO:0001823]; metanephric collecting duct development [GO:0072205]; monocyte differentiation [GO:0030224]; negative regulation of apoptotic process [GO:0043066]; negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway [GO:0072097]; negative regulation of branching involved in ureteric bud morphogenesis [GO:0090191]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell proliferation involved in heart morphogenesis [GO:2000137]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of glomerular mesangial cell proliferation [GO:0072125]; negative regulation of glomerulus development [GO:0090194]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of mesenchymal cell proliferation involved in ureter development [GO:0072200]; negative regulation of metanephric comma-shaped body morphogenesis [GO:2000007]; negative regulation of metanephric S-shaped body morphogenesis [GO:2000005]; negative regulation of miRNA transcription [GO:1902894]; negative regulation of mitotic nuclear division [GO:0045839]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of phosphorylation [GO:0042326]; negative regulation of prostatic bud formation [GO:0060686]; negative regulation of striated muscle tissue development [GO:0045843]; negative regulation of T cell differentiation in thymus [GO:0033085]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; neural tube closure [GO:0001843]; neuron fate commitment [GO:0048663]; odontogenesis [GO:0042476]; odontogenesis of dentin-containing tooth [GO:0042475]; osteoblast differentiation [GO:0001649]; outflow tract septum morphogenesis [GO:0003148]; pericyte cell differentiation [GO:1904238]; pharyngeal arch artery morphogenesis [GO:0061626]; pituitary gland development [GO:0021983]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of bone mineralization [GO:0030501]; positive regulation of branching involved in lung morphogenesis [GO:0061047]; positive regulation of cardiac muscle fiber development [GO:0055020]; positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis [GO:1905312]; positive regulation of cartilage development [GO:0061036]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation involved in outflow tract morphogenesis [GO:1901964]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epidermal cell differentiation [GO:0045606]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of kidney development [GO:0090184]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of ossification [GO:0045778]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of primary miRNA processing [GO:2000636]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein binding [GO:0032092]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; prostatic bud formation [GO:0060513]; protein localization to nucleus [GO:0034504]; pulmonary artery endothelial tube morphogenesis [GO:0061155]; pulmonary valve morphogenesis [GO:0003184]; regulation of branching involved in prostate gland morphogenesis [GO:0060687]; regulation of cell fate commitment [GO:0010453]; regulation of mesodermal cell differentiation [GO:1905770]; regulation of odontogenesis of dentin-containing tooth [GO:0042487]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein import into nucleus [GO:0042306]; regulation of smooth muscle cell differentiation [GO:0051150]; renal system process [GO:0003014]; secondary heart field specification [GO:0003139]; sinoatrial node development [GO:0003163]; SMAD protein signal transduction [GO:0060395]; smooth muscle tissue development [GO:0048745]; specification of animal organ position [GO:0010159]; specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway [GO:0072101]; steroid hormone mediated signaling pathway [GO:0043401]; telencephalon development [GO:0021537]; telencephalon regionalization [GO:0021978]; tendon cell differentiation [GO:0035990]; trachea development [GO:0060438]; trachea formation [GO:0060440]; transcription by RNA polymerase II [GO:0006366]; type B pancreatic cell development [GO:0003323]; ureter epithelial cell differentiation [GO:0072192]; ureter smooth muscle cell differentiation [GO:0072193]; ureteric bud development [GO:0001657] endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615] BMP receptor binding [GO:0070700]; chemoattractant activity [GO:0042056]; co-receptor binding [GO:0039706]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; heparin binding [GO:0008201] 0.83272 0.19884 LVHHNVTR 0 0 11.3893 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P12694 ODBA_HUMAN "2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDE1A) (BCKDH E1-alpha)" BCKDHA Homo sapiens (Human) branched-chain amino acid catabolic process [GO:0009083] mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; carboxy-lyase activity [GO:0016831]; metal ion binding [GO:0046872] 0.86341 0.080688 EAGVLMYR 0 9.60446 9.57461 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P12755 SKI_HUMAN Ski oncogene (Proto-oncogene c-Ski) SKI Homo sapiens (Human) anterior/posterior axis specification [GO:0009948]; bone morphogenesis [GO:0060349]; camera-type eye development [GO:0043010]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle cell proliferation [GO:0060038]; cell motility [GO:0048870]; embryonic limb morphogenesis [GO:0030326]; face morphogenesis [GO:0060325]; lens morphogenesis in camera-type eye [GO:0002089]; myelination in peripheral nervous system [GO:0022011]; myotube differentiation [GO:0014902]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of Schwann cell proliferation [GO:0010626]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neural tube closure [GO:0001843]; nose morphogenesis [GO:0043585]; olfactory bulb development [GO:0021772]; positive regulation of DNA binding [GO:0043388]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; retina development in camera-type eye [GO:0060041]; roof of mouth development [GO:0060021]; skeletal muscle fiber development [GO:0048741]; SMAD protein signal transduction [GO:0060395]; somatic stem cell population maintenance [GO:0035019]; transforming growth factor beta receptor signaling pathway [GO:0007179] centrosome [GO:0005813]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; transcription regulator complex [GO:0005667]; transcription repressor complex [GO:0017053] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription factor binding [GO:0140297]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; histone deacetylase inhibitor activity [GO:0046811]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; SMAD binding [GO:0046332]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]" 0.96905 -5.7712 EKFDYGNKYK 0 0 0 0 0 0 0 0 0 0 0 0 0 11.129 0 0 0 10.5669 10.5269 0 9.83401 0 0 0 0 12.7246 0 P12757 SKIL_HUMAN Ski-like protein (Ski-related oncogene) (Ski-related protein) SKIL SNO Homo sapiens (Human) blastocyst formation [GO:0001825]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lens fiber cell differentiation [GO:0070306]; lymphocyte homeostasis [GO:0002260]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell differentiation [GO:0045596]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of axonogenesis [GO:0050772]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902231]; regulation of cell cycle [GO:0051726]; response to antibiotic [GO:0046677]; response to cytokine [GO:0034097]; response to growth factor [GO:0070848]; skeletal muscle tissue development [GO:0007519]; spermatogenesis [GO:0007283]; transforming growth factor beta receptor signaling pathway [GO:0007179] acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991] "chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein-containing complex binding [GO:0044877]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; SMAD binding [GO:0046332]" 0.96929 -3.0675 DVICEDDKGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1257 0 10.0727 0 0 0 0 0 0 0 0 P12814 ACTN1_HUMAN Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (F-actin cross-linking protein) (Non-muscle alpha-actinin-1) ACTN1 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; actin filament network formation [GO:0051639]; actin filament organization [GO:0007015]; focal adhesion assembly [GO:0048041]; muscle cell development [GO:0055001]; platelet formation [GO:0030220]; platelet morphogenesis [GO:0036344]; regulation of apoptotic process [GO:0042981] brush border [GO:0005903]; cell junction [GO:0030054]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fascia adherens [GO:0005916]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; pseudopodium [GO:0031143]; ruffle [GO:0001726]; stress fiber [GO:0001725]; Z disc [GO:0030018] actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cytoskeletal regulatory protein binding [GO:0005519]; double-stranded RNA binding [GO:0003725]; integrin binding [GO:0005178]; nuclear receptor coactivator activity [GO:0030374]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; structural constituent of postsynapse [GO:0099186]; transmembrane transporter binding [GO:0044325]; vinculin binding [GO:0017166] 0.94905 -1.3718 ALDFIASK 0 0 0 0 0 0 0 0 0 0 0 9.80281 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P12821 ACE_HUMAN "Angiotensin-converting enzyme (ACE) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form]" ACE DCP DCP1 Homo sapiens (Human) aging [GO:0007568]; amyloid-beta metabolic process [GO:0050435]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; angiotensin maturation [GO:0002003]; animal organ regeneration [GO:0031100]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; arachidonic acid secretion [GO:0050482]; blood vessel diameter maintenance [GO:0097746]; blood vessel remodeling [GO:0001974]; bradykinin catabolic process [GO:0010815]; brain development [GO:0007420]; cell proliferation in bone marrow [GO:0071838]; cellular response to aldosterone [GO:1904045]; cellular response to glucose stimulus [GO:0071333]; eating behavior [GO:0042755]; embryo development ending in birth or egg hatching [GO:0009792]; female pregnancy [GO:0007565]; heart contraction [GO:0060047]; hematopoietic stem cell differentiation [GO:0060218]; hormone catabolic process [GO:0042447]; hormone metabolic process [GO:0042445]; kidney development [GO:0001822]; lung alveolus development [GO:0048286]; male gonad development [GO:0008584]; mononuclear cell proliferation [GO:0032943]; negative regulation of calcium ion import [GO:0090281]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of protein binding [GO:0032091]; negative regulation of renal sodium excretion [GO:0035814]; neutrophil mediated immunity [GO:0002446]; peptide catabolic process [GO:0043171]; positive regulation of apoptotic process [GO:0043065]; positive regulation of inflammatory response [GO:0050729]; positive regulation of neurogenesis [GO:0050769]; positive regulation of peptidyl-cysteine S-nitrosylation [GO:2000170]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of systemic arterial blood pressure [GO:0003084]; positive regulation of vasoconstriction [GO:0045907]; post-transcriptional regulation of gene expression [GO:0010608]; proteolysis [GO:0006508]; regulation of angiotensin metabolic process [GO:0060177]; regulation of blood pressure [GO:0008217]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of renal output by angiotensin [GO:0002019]; regulation of smooth muscle cell migration [GO:0014910]; regulation of synaptic plasticity [GO:0048167]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; response to dexamethasone [GO:0071548]; response to hypoxia [GO:0001666]; response to laminar fluid shear stress [GO:0034616]; response to lipopolysaccharide [GO:0032496]; response to nutrient levels [GO:0031667]; response to thyroid hormone [GO:0097066]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; spermatogenesis [GO:0007283]; substance P catabolic process [GO:0010814]; vasoconstriction [GO:0042310] basal plasma membrane [GO:0009925]; brush border membrane [GO:0031526]; endosome [GO:0005768]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; plasma membrane [GO:0005886]; sperm midpiece [GO:0097225] actin binding [GO:0003779]; bradykinin receptor binding [GO:0031711]; calmodulin binding [GO:0005516]; carboxypeptidase activity [GO:0004180]; chloride ion binding [GO:0031404]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; heterocyclic compound binding [GO:1901363]; metallodipeptidase activity [GO:0070573]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; mitogen-activated protein kinase binding [GO:0051019]; mitogen-activated protein kinase kinase binding [GO:0031434]; peptidase activity [GO:0008233]; peptidyl-dipeptidase activity [GO:0008241]; tripeptidyl-peptidase activity [GO:0008240]; zinc ion binding [GO:0008270] 0.89896 -0.62034 VFDGSITK 0 0 0 9.82841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.11194 0 0 0 0 0 0 0 10.4257 P12829 MYL4_HUMAN "Myosin light chain 4 (Myosin light chain 1, embryonic muscle/atrial isoform) (Myosin light chain alkali GT-1 isoform)" MYL4 MLC1 PRO1957 Homo sapiens (Human) cardiac muscle contraction [GO:0060048]; positive regulation of ATP-dependent activity [GO:0032781]; regulation of the force of heart contraction [GO:0002026] A band [GO:0031672]; cytosol [GO:0005829]; myosin II complex [GO:0016460] actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; calcium ion binding [GO:0005509]; myosin II heavy chain binding [GO:0032038] 0.67148 0.39371 ITYGQCGDVLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.78722 0 0 0 0 0 0 0 0 0 P12882 MYH1_HUMAN "Myosin-1 (Myosin heavy chain 1) (Myosin heavy chain 2x) (MyHC-2x) (Myosin heavy chain IIx/d) (MyHC-IIx/d) (Myosin heavy chain, skeletal muscle, adult 1)" MYH1 Homo sapiens (Human) muscle contraction [GO:0006936] A band [GO:0031672]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; intercalated disc [GO:0014704]; muscle myosin complex [GO:0005859]; myosin filament [GO:0032982]; myosin II complex [GO:0016460] actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; microfilament motor activity [GO:0000146] 0.95233 -1.4748 ADIAESQVNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.97694 P12883 MYH7_HUMAN "Myosin-7 (Myosin heavy chain 7) (Myosin heavy chain slow isoform) (MyHC-slow) (Myosin heavy chain, cardiac muscle beta isoform) (MyHC-beta)" MYH7 MYHCB Homo sapiens (Human) adult heart development [GO:0007512]; ATP metabolic process [GO:0046034]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy in response to stress [GO:0014898]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; regulation of heart rate [GO:0002027]; regulation of slow-twitch skeletal muscle fiber contraction [GO:0031449]; regulation of the force of heart contraction [GO:0002026]; regulation of the force of skeletal muscle contraction [GO:0014728]; sarcomere organization [GO:0045214]; skeletal muscle contraction [GO:0003009]; striated muscle contraction [GO:0006941]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010] cytoplasm [GO:0005737]; muscle myosin complex [GO:0005859]; myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]; myosin II complex [GO:0016460]; sarcomere [GO:0030017]; stress fiber [GO:0001725]; Z disc [GO:0030018] actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; microfilament motor activity [GO:0000146] 0.95811 -1.6698 ADIAESQVNK 0 0 0 0 0 0 0 11.6745 0 0 0 0 0 0 0 11.008 0 0 0 9.59647 0 0 10.3721 0 0 0 0 P12955 PEPD_HUMAN Xaa-Pro dipeptidase (X-Pro dipeptidase) (EC 3.4.13.9) (Imidodipeptidase) (Peptidase D) (Proline dipeptidase) (Prolidase) PEPD PRD Homo sapiens (Human) amino acid metabolic process [GO:0006520]; collagen catabolic process [GO:0030574]; negative regulation of programmed cell death [GO:0043069]; proteolysis [GO:0006508] extracellular exosome [GO:0070062] manganese ion binding [GO:0030145]; metalloaminopeptidase activity [GO:0070006]; metallocarboxypeptidase activity [GO:0004181]; peptidase activity [GO:0008233]; proline dipeptidase activity [GO:0102009] 0.916 -0.80961 AFTPFSGPK 0 0 0 15.9495 0 0 0 17.174 0 0 0 0 0 16.0788 0 16.9372 0 0 0 0 0 0 0 0 0 0 0 P12956 XRCC6_HUMAN X-ray repair cross-complementing protein 6 (EC 3.6.4.-) (EC 4.2.99.-) (5'-deoxyribose-5-phosphate lyase Ku70) (5'-dRP lyase Ku70) (70 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 1) (ATP-dependent DNA helicase II 70 kDa subunit) (CTC box-binding factor 75 kDa subunit) (CTC75) (CTCBF) (DNA repair protein XRCC6) (Lupus Ku autoantigen protein p70) (Ku70) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 6) XRCC6 G22P1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; cellular response to gamma radiation [GO:0071480]; DNA ligation [GO:0006266]; double-strand break repair via classical nonhomologous end joining [GO:0097680]; double-strand break repair via nonhomologous end joining [GO:0006303]; innate immune response [GO:0045087]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of lymphocyte differentiation [GO:0045621]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of transcription by RNA polymerase II [GO:0045944]; recombinational repair [GO:0000725]; regulation of smooth muscle cell proliferation [GO:0048660]; telomere maintenance [GO:0000723] "chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; DNA-dependent protein kinase complex [GO:0070418]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; Ku70:Ku80 complex [GO:0043564]; membrane [GO:0016020]; nonhomologous end joining complex [GO:0070419]; nuclear telomere cap complex [GO:0000783]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; secretory granule lumen [GO:0034774]; transcription regulator complex [GO:0005667]" "5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent activity, acting on DNA [GO:0008094]; cyclin binding [GO:0030332]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; double-stranded DNA binding [GO:0003690]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; telomeric DNA binding [GO:0042162]; transcription cis-regulatory region binding [GO:0000976]" 0 4.624 DSLIFLVDASK 0 0 0 0 0 0 0 10.1589 0 0 8.82737 0 0 11.0904 0 10.887 0 8.77673 11.0351 11.0091 12.7498 8.65821 0 0 12.08 0 0 P13010 XRCC5_HUMAN X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (86 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 2) (ATP-dependent DNA helicase II 80 kDa subunit) (CTC box-binding factor 85 kDa subunit) (CTC85) (CTCBF) (DNA repair protein XRCC5) (Ku80) (Ku86) (Lupus Ku autoantigen protein p86) (Nuclear factor IV) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)) XRCC5 G22P2 Homo sapiens (Human) "activation of innate immune response [GO:0002218]; brain development [GO:0007420]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to fatty acid [GO:0071398]; cellular response to gamma radiation [GO:0071480]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to X-ray [GO:0071481]; DNA damage response [GO:0006974]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via nonhomologous end joining [GO:0006303]; hematopoietic stem cell differentiation [GO:0060218]; hematopoietic stem cell proliferation [GO:0071425]; innate immune response [GO:0045087]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of t-circle formation [GO:1904430]; neurogenesis [GO:0022008]; positive regulation of catalytic activity [GO:0043085]; positive regulation of neurogenesis [GO:0050769]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein localization to chromosome, telomeric region [GO:0070198]; recombinational repair [GO:0000725]; regulation of smooth muscle cell proliferation [GO:0048660]; regulation of telomere maintenance [GO:0032204]; response to xenobiotic stimulus [GO:0009410]; small-subunit processome assembly [GO:0034462]; telomere maintenance [GO:0000723]" "chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; DNA-dependent protein kinase complex [GO:0070418]; extracellular region [GO:0005576]; Ku70:Ku80 complex [GO:0043564]; membrane [GO:0016020]; nonhomologous end joining complex [GO:0070419]; nuclear telomere cap complex [GO:0000783]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774]; site of DNA damage [GO:0090734]; small-subunit processome [GO:0032040]" "ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent activity, acting on DNA [GO:0008094]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA end binding [GO:0045027]; DNA helicase activity [GO:0003678]; double-stranded DNA binding [GO:0003690]; enzyme activator activity [GO:0008047]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; telomeric DNA binding [GO:0042162]; transcription cis-regulatory region binding [GO:0000976]; U3 snoRNA binding [GO:0034511]; ubiquitin protein ligase binding [GO:0031625]" 0 4.7472 ANPQVGVAFPHIK 8.82219 8.67264 8.96197 0 0 0 10.1744 9.03593 9.19177 0 0 9.48069 11.2298 11.7973 10.1565 11.2528 0 0 11.0664 0 0 0 0 0 0 9.71761 9.56402 P13051 UNG_HUMAN Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) UNG DGU UNG1 UNG15 Homo sapiens (Human) "base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]; depyrimidination [GO:0045008]; DNA repair [GO:0006281]; isotype switching [GO:0045190]; negative regulation of apoptotic process [GO:0043066]; somatic hypermutation of immunoglobulin genes [GO:0016446]" mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] damaged DNA binding [GO:0003684]; ribosomal small subunit binding [GO:0043024]; uracil DNA N-glycosylase activity [GO:0004844] 0.91586 -0.80979 GSAIDRK 0 8.41507 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P13056 NR2C1_HUMAN Nuclear receptor subfamily 2 group C member 1 (Orphan nuclear receptor TR2) (Testicular receptor 2) NR2C1 TR2 Homo sapiens (Human) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of retinoic acid receptor signaling pathway [GO:0048386] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; PML body [GO:0016605] "DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; histone deacetylase binding [GO:0042826]; nuclear receptor activity [GO:0004879]; nuclear steroid receptor activity [GO:0003707]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]; signaling receptor activity [GO:0038023]; zinc ion binding [GO:0008270]" 0.885 -0.37889 FQEKAYVEFQDYITK 0 0 0 0 0 0 0 0 0 0 0 10.9624 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P13196 HEM1_HUMAN "5-aminolevulinate synthase, non-specific, mitochondrial (ALAS-H) (EC 2.3.1.37) (5-aminolevulinic acid synthase 1) (Delta-ALA synthase 1) (Delta-aminolevulinate synthase 1)" ALAS1 ALAS3 ALASH OK/SW-cl.121 Homo sapiens (Human) erythrocyte development [GO:0048821]; heme biosynthetic process [GO:0006783]; hemoglobin biosynthetic process [GO:0042541]; protoporphyrinogen IX biosynthetic process [GO:0006782]; response to bile acid [GO:1903412] cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] 5-aminolevulinate synthase activity [GO:0003870]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170] 0.92452 -1.0088 MESVVRRCPFLSR 0 0 0 0 0 0 0 8.25191 0 0 9.06641 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P13232 IL7_HUMAN Interleukin-7 (IL-7) IL7 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; B cell proliferation [GO:0042100]; bone resorption [GO:0045453]; cell-cell signaling [GO:0007267]; cytokine-mediated signaling pathway [GO:0019221]; extrinsic apoptotic signaling pathway [GO:0097191]; homeostasis of number of cells within a tissue [GO:0048873]; humoral immune response [GO:0006959]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; organ growth [GO:0035265]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine-mediated signaling pathway [GO:0001961]; positive regulation of organ growth [GO:0046622]; positive regulation of T cell differentiation [GO:0045582]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; T cell lineage commitment [GO:0002360] collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615] cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-7 receptor binding [GO:0005139] 0.96371 -2.1122 LNDLCFLK 0 0 0 0 9.4223 0 0 0 0 9.91907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P13385 TDGF1_HUMAN Teratocarcinoma-derived growth factor 1 (Cripto-1 growth factor) (CRGF) (Epidermal growth factor-like cripto protein CR1) TDGF1 CRIPTO Homo sapiens (Human) "anatomical structure development [GO:0048856]; anterior/posterior axis specification, embryo [GO:0008595]; cell differentiation [GO:0030154]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to interleukin-6 [GO:0071354]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to type II interferon [GO:0071346]; embryo development ending in birth or egg hatching [GO:0009792]; heart development [GO:0007507]; mammary gland development [GO:0030879]; morphogenesis of a branching structure [GO:0001763]; negative regulation of apoptotic process [GO:0043066]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of signal transduction [GO:0009966]" apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; membrane raft [GO:0045121]; plasma membrane [GO:0005886] growth factor activity [GO:0008083]; signaling receptor binding [GO:0005102] 0.87253 0.037161 VPPMGIQHSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9632 0 0 0 0 0 0 0 0 0 0 0 P13473 LAMP2_HUMAN Lysosome-associated membrane glycoprotein 2 (LAMP-2) (Lysosome-associated membrane protein 2) (CD107 antigen-like family member B) (LGP-96) (CD antigen CD107b) LAMP2 Homo sapiens (Human) autophagosome maturation [GO:0097352]; cellular response to starvation [GO:0009267]; chaperone-mediated autophagy [GO:0061684]; lysosomal protein catabolic process [GO:1905146]; muscle cell cellular homeostasis [GO:0046716]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of protein-containing complex assembly [GO:0031333]; protein catabolic process [GO:0030163]; protein import [GO:0017038]; protein stabilization [GO:0050821]; protein targeting [GO:0006605]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; regulation of protein stability [GO:0031647] autolysosome [GO:0044754]; autophagosome membrane [GO:0000421]; azurophil granule membrane [GO:0035577]; chaperone-mediated autophagy translocation complex [GO:0061742]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; platelet dense granule membrane [GO:0031088]; trans-Golgi network [GO:0005802] enzyme binding [GO:0019899]; protein domain specific binding [GO:0019904]; signaling adaptor activity [GO:0035591] 0.079767 1.2448 IPLNDLFR 0 0 0 0 0 0 8.87946 0 0 0 9.0895 0 0 0 0 0 0 0 0 9.8404 9.75689 9.13545 0 0 10.286 9.93049 0 P13489 RINI_HUMAN Ribonuclease inhibitor (Placental ribonuclease inhibitor) (Placental RNase inhibitor) (Ribonuclease/angiogenin inhibitor 1) (RAI) RNH1 PRI RNH Homo sapiens (Human) cell migration [GO:0016477]; mRNA catabolic process [GO:0006402]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of angiogenesis [GO:0045765]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315] angiogenin-PRI complex [GO:0032311]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lamellipodium [GO:0030027]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] ribonuclease inhibitor activity [GO:0008428] 0.96395 -2.2246 DISSALR 0 0 12.3682 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P13497 BMP1_HUMAN Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.19) (Mammalian tolloid protein) (mTld) (Procollagen C-proteinase) (PCP) BMP1 PCOLC Homo sapiens (Human) cartilage condensation [GO:0001502]; cell differentiation [GO:0030154]; collagen fibril organization [GO:0030199]; dorsal/ventral pattern formation [GO:0009953]; ossification [GO:0001503]; positive regulation of cartilage development [GO:0061036]; protein processing [GO:0016485]; proteolysis [GO:0006508]; skeletal system development [GO:0001501] extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; vesicle [GO:0031982] calcium ion binding [GO:0005509]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270] 0.91503 -0.79147 ENIQPGQEYNFLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4011 0 0 0 0 0 P13521 SCG2_HUMAN Secretogranin-2 (Chromogranin-C) (Secretogranin II) (SgII) [Cleaved into: Secretoneurin (SN); Manserin] SCG2 CHGC Homo sapiens (Human) angiogenesis [GO:0001525]; endothelial cell migration [GO:0043542]; eosinophil chemotaxis [GO:0048245]; induction of positive chemotaxis [GO:0050930]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive chemotaxis [GO:0050918]; positive regulation of endothelial cell proliferation [GO:0001938]; protein secretion [GO:0009306] endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; neuronal dense core vesicle [GO:0098992]; secretory granule [GO:0030141] chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125] 0.89892 -0.68585 DQELGEYLAR 0 8.85081 0 0 0 0 0 0 0 0 0 10.0868 0 0 0 0 0 0 0 0 0 0 0 0 9.26285 0 0 P13533 MYH6_HUMAN "Myosin-6 (Myosin heavy chain 6) (Myosin heavy chain, cardiac muscle alpha isoform) (MyHC-alpha)" MYH6 MYHCA Homo sapiens (Human) adult heart development [GO:0007512]; ATP metabolic process [GO:0046034]; atrial cardiac muscle tissue morphogenesis [GO:0055009]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy in response to stress [GO:0014898]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; myofibril assembly [GO:0030239]; regulation of ATP-dependent activity [GO:0043462]; regulation of blood pressure [GO:0008217]; regulation of heart contraction [GO:0008016]; regulation of heart growth [GO:0060420]; regulation of heart rate [GO:0002027]; regulation of the force of heart contraction [GO:0002026]; sarcomere organization [GO:0045214]; striated muscle contraction [GO:0006941]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; visceral muscle development [GO:0007522] cytoplasm [GO:0005737]; cytosol [GO:0005829]; muscle myosin complex [GO:0005859]; myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]; myosin II complex [GO:0016460]; sarcomere [GO:0030017]; stress fiber [GO:0001725]; Z disc [GO:0030018] actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; microfilament motor activity [GO:0000146]; myosin phosphatase activity [GO:0017018]; protein kinase binding [GO:0019901] 0.95838 -1.6797 ADIAESQVNK 0 0 0 0 0 0 0 0 0 0 12.4564 0 0 9.72697 11.1534 0 0 0 0 0 0 0 0 0 9.34532 11.6631 0 P13535 MYH8_HUMAN "Myosin-8 (Myosin heavy chain 8) (Myosin heavy chain, skeletal muscle, perinatal) (MyHC-perinatal)" MYH8 Homo sapiens (Human) ATP metabolic process [GO:0046034]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; skeletal muscle contraction [GO:0003009] cytoplasm [GO:0005737]; cytosol [GO:0005829]; muscle myosin complex [GO:0005859]; myosin filament [GO:0032982]; myosin II complex [GO:0016460]; sarcomere [GO:0030017] actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; calmodulin binding [GO:0005516]; microfilament motor activity [GO:0000146]; myosin light chain binding [GO:0032027]; myosin phosphatase activity [GO:0017018]; structural constituent of muscle [GO:0008307] 0.96262 -2.094 ADIAESQVNK 0 0 0 9.41785 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P13591 NCAM1_HUMAN Neural cell adhesion molecule 1 (N-CAM-1) (NCAM-1) (CD antigen CD56) NCAM1 NCAM Homo sapiens (Human) cell adhesion [GO:0007155]; commissural neuron axon guidance [GO:0071679]; regulation of semaphorin-plexin signaling pathway [GO:2001260] cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; plasma membrane [GO:0005886] virus receptor activity [GO:0001618] 0.88132 -0.018062 ALSSEWKPEIR 0 0 0 0 0 0 0 0 0 0 10.6042 0 0 0 0 0 10.1436 0 0 0 0 0 0 0 0 0 0 P13612 ITA4_HUMAN Integrin alpha-4 (CD49 antigen-like family member D) (Integrin alpha-IV) (VLA-4 subunit alpha) (CD antigen CD49d) ITGA4 CD49D Homo sapiens (Human) axonogenesis involved in innervation [GO:0060385]; B cell differentiation [GO:0030183]; cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion [GO:0098609]; cell-cell adhesion in response to extracellular stimulus [GO:0140039]; cell-cell adhesion mediated by integrin [GO:0033631]; cell-matrix adhesion [GO:0007160]; cell-matrix adhesion involved in ameboidal cell migration [GO:0003366]; cellular response to amyloid-beta [GO:1904646]; cellular response to cytokine stimulus [GO:0071345]; clathrin-dependent extracellular exosome endocytosis [GO:1990771]; diapedesis [GO:0050904]; endodermal cell differentiation [GO:0035987]; heterotypic cell-cell adhesion [GO:0034113]; import into cell [GO:0098657]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte tethering or rolling [GO:0050901]; negative regulation of protein homodimerization activity [GO:0090074]; neuron projection extension [GO:1990138]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of T cell migration [GO:2000406]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; receptor clustering [GO:0043113]; substrate adhesion-dependent cell spreading [GO:0034446] cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; growth cone [GO:0030426]; integrin alpha4-beta1 complex [GO:0034668]; integrin alpha4-beta7 complex [GO:0034669]; integrin complex [GO:0008305]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886] cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; fibronectin binding [GO:0001968]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; protein antigen binding [GO:1990405] 0.96387 -2.1085 DSWSYINSKSNDD 0 0 0 10.7233 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P13631 RARG_HUMAN Retinoic acid receptor gamma (RAR-gamma) (Nuclear receptor subfamily 1 group B member 3) RARG NR1B3 Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; canonical Wnt signaling pathway [GO:0060070]; cell differentiation [GO:0030154]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to retinoic acid [GO:0071300]; embryonic camera-type eye development [GO:0031076]; embryonic eye morphogenesis [GO:0048048]; embryonic hindlimb morphogenesis [GO:0035116]; face development [GO:0060324]; glandular epithelial cell development [GO:0002068]; growth plate cartilage chondrocyte growth [GO:0003430]; Harderian gland development [GO:0070384]; hormone-mediated signaling pathway [GO:0009755]; multicellular organism growth [GO:0035264]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of programmed cell death [GO:0043068]; positive regulation of transcription by RNA polymerase II [GO:0045944]; prostate gland epithelium morphogenesis [GO:0060740]; regulation of cell size [GO:0008361]; regulation of myelination [GO:0031641]; regulation of myeloid cell differentiation [GO:0045637]; response to retinoic acid [GO:0032526]; retinoic acid receptor signaling pathway [GO:0048384]; stem cell proliferation [GO:0072089]; trachea cartilage development [GO:0060534] chromatin [GO:0000785]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; nuclear receptor activity [GO:0004879]; nuclear retinoid X receptor binding [GO:0046965]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]; zinc ion binding [GO:0008270]" 0.96331 -2.6433 CQYCRLQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.66183 0 0 0 0 0 P13637 AT1A3_HUMAN Sodium/potassium-transporting ATPase subunit alpha-3 (Na(+)/K(+) ATPase alpha-3 subunit) (EC 7.2.2.13) (Na(+)/K(+) ATPase alpha(III) subunit) (Sodium pump subunit alpha-3) ATP1A3 Homo sapiens (Human) cell communication by electrical coupling involved in cardiac conduction [GO:0086064]; cellular response to amyloid-beta [GO:1904646]; cellular response to retinoic acid [GO:0071300]; cellular response to steroid hormone stimulus [GO:0071383]; cellular response to thyroid hormone stimulus [GO:0097067]; cerebral cortex development [GO:0021987]; intracellular potassium ion homeostasis [GO:0030007]; intracellular sodium ion homeostasis [GO:0006883]; neuron projection maintenance [GO:1990535]; potassium ion import across plasma membrane [GO:1990573]; proton transmembrane transport [GO:1902600]; regulation of resting membrane potential [GO:0060075]; response to glycoside [GO:1903416]; sodium ion export across plasma membrane [GO:0036376] axon [GO:0030424]; calyx of Held [GO:0044305]; dendritic spine head [GO:0044327]; dendritic spine neck [GO:0044326]; endoplasmic reticulum [GO:0005783]; extracellular vesicle [GO:1903561]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuron to neuron synapse [GO:0098984]; neuronal cell body [GO:0043025]; neuronal cell body membrane [GO:0032809]; organelle membrane [GO:0031090]; photoreceptor inner segment [GO:0001917]; photoreceptor inner segment membrane [GO:0060342]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; sodium:potassium-exchanging ATPase complex [GO:0005890]; synapse [GO:0045202] amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; D1 dopamine receptor binding [GO:0031748]; metal ion binding [GO:0046872]; P-type sodium:potassium-exchanging transporter activity [GO:0005391]; protein-folding chaperone binding [GO:0051087]; steroid hormone binding [GO:1990239] 0.88406 -0.29643 GVGIISEGNETVEDIAAR 0 0 0 0 0 0 0 0 0 9.45156 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P13639 EF2_HUMAN Elongation factor 2 (EF-2) (EC 3.6.5.-) EEF2 EF2 Homo sapiens (Human) hematopoietic progenitor cell differentiation [GO:0002244]; positive regulation of translation [GO:0045727]; translational elongation [GO:0006414] aggresome [GO:0016235]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; polysome [GO:0005844]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774]; synapse [GO:0045202] cadherin binding [GO:0045296]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein kinase binding [GO:0019901]; ribosome binding [GO:0043022]; RNA binding [GO:0003723]; translation elongation factor activity [GO:0003746] 0 23.451 AGIIASAR 10.8896 10.2282 10.2999 9.72965 8.66245 8.85365 12.0023 11.2954 12.1547 11.5882 12.1017 11.6745 11.6318 12.284 13.9753 12.3261 12.8828 12.7382 12.3695 11.5246 11.9858 11.5584 9.9747 11.9819 13.5657 13.7388 13.6864 P13645 K1C10_HUMAN "Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10)" KRT10 KPP Homo sapiens (Human) epithelial cell differentiation [GO:0030855]; intermediate filament organization [GO:0045109]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; positive regulation of epidermis development [GO:0045684]; protein heterotetramerization [GO:0051290] cell surface [GO:0009986]; cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intermediate filament [GO:0005882]; keratin filament [GO:0045095]; membrane [GO:0016020]; nucleus [GO:0005634] protein heterodimerization activity [GO:0046982]; structural constituent of skin epidermis [GO:0030280] 0 323.31 AETECQNTEYQQLLDIK 16.0165 15.9566 16.0182 10.317 11.2488 10.4211 15.8117 16.0803 15.9987 15.8234 15.7358 15.8768 13.864 13.7457 14.1773 15.8328 15.7397 15.679 14.5159 14.1319 14.1943 13.8084 13.9238 13.8631 14.621 14.983 13.9219 P13647 K2C5_HUMAN "Keratin, type II cytoskeletal 5 (58 kDa cytokeratin) (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (Type-II keratin Kb5)" KRT5 Homo sapiens (Human) epidermis development [GO:0008544]; intermediate filament polymerization [GO:0045107]; keratinization [GO:0031424]; regulation of cell migration [GO:0030334]; regulation of protein localization [GO:0032880]; response to mechanical stimulus [GO:0009612] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; keratin filament [GO:0045095]; membrane [GO:0016020]; nucleus [GO:0005634] scaffold protein binding [GO:0097110]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of skin epidermis [GO:0030280] 0 6.4312 AQYEEIANR 10.3175 10.581 10.9825 0 0 0 10.036 10.7705 10.1262 10.2817 13.1221 11.3362 0 0 0 11.5979 11.6716 10.741 0 0 0 9.57442 0 0 0 10.0692 0 P13667 PDIA4_HUMAN Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72) PDIA4 ERP70 ERP72 Homo sapiens (Human) chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein secretion [GO:0009306]; response to endoplasmic reticulum stress [GO:0034976] cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; melanosome [GO:0042470] protein disulfide isomerase activity [GO:0003756]; protein-disulfide reductase activity [GO:0015035]; RNA binding [GO:0003723] 0 8.9919 AATQFWRSK 9.64461 9.4566 10.2542 0 0 10.2655 10.4453 10.3644 11.06 9.69582 0 0 0 8.74106 9.51035 0 9.3338 0 10.1509 11.275 0 0 9.59341 9.88868 11.5994 11.9356 12.0748 P13671 CO6_HUMAN Complement component C6 C6 Homo sapiens (Human) "complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; in utero embryonic development [GO:0001701]; innate immune response [GO:0045087]; killing of cells of another organism [GO:0031640]; positive regulation of immune response [GO:0050778]" extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579] 0.96296 -2.5296 IEEADCKNK 10.5046 0 0 0 0 0 9.33255 0 0 0 0 0 0 0 0 11.093 0 0 0 0 0 0 0 0 0 0 0 P13674 P4HA1_HUMAN "Prolyl 4-hydroxylase subunit alpha-1 (4-PH alpha-1) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1)" P4HA1 P4HA Homo sapiens (Human) collagen fibril organization [GO:0030199]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; procollagen-proline 4-dioxygenase complex [GO:0016222] identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; L-ascorbic acid binding [GO:0031418]; procollagen-proline 4-dioxygenase activity [GO:0004656] 0.87078 0.054613 AEEDKLEQIK 0 0 0 0 0 0 0 0 0 10.56 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.45508 P13725 ONCM_HUMAN Oncostatin-M (OSM) OSM Homo sapiens (Human) immune response [GO:0006955]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of hormone secretion [GO:0046888]; oncostatin-M-mediated signaling pathway [GO:0038165]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of hematopoietic stem cell differentiation [GO:1902036] extracellular region [GO:0005576]; extracellular space [GO:0005615] cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; oncostatin-M receptor binding [GO:0005147] 0.63126 0.40377 FLHGYHR 0 0 0 0 0 0 0 0 0 0 0 0 0 8.85664 0 0 0 0 0 0 0 0 0 0 0 0 0 P13726 TF_HUMAN Tissue factor (TF) (Coagulation factor III) (Thromboplastin) (CD antigen CD142) F3 Homo sapiens (Human) "activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; blood coagulation, fibrin clot formation [GO:0072378]; blood coagulation, intrinsic pathway [GO:0007597]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; proteolysis [GO:0006508]; response to wounding [GO:0009611]" cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; serine-type endopeptidase complex [GO:1905370]; serine-type peptidase complex [GO:1905286] phospholipid binding [GO:0005543]; protease binding [GO:0002020] 0.87222 0.030685 STDSPVECMGQEK 0 0 0 0 0 0 0 9.64254 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P13747 HLAE_HUMAN "HLA class I histocompatibility antigen, alpha chain E (MHC class I antigen E) [Cleaved into: Soluble HLA class I histocompatibility antigen, alpha chain E (sHLA-E)]" HLA-E HLA-6.2 HLAE Homo sapiens (Human) "adaptive immune response [GO:0002250]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent [GO:0002486]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class Ib [GO:0002477]; CD8-positive, alpha-beta T cell activation [GO:0036037]; defense response to Gram-positive bacterium [GO:0050830]; immune response [GO:0006955]; innate immune response [GO:0045087]; natural killer cell tolerance induction [GO:0002519]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; positive regulation of antibody-dependent cellular cytotoxicity [GO:0001815]; positive regulation of CD8-positive, alpha-beta T cell activation [GO:2001187]; positive regulation of CD8-positive, alpha-beta T cell proliferation [GO:2000566]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of natural killer cell cytokine production [GO:0002729]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of natural killer cell mediated immunity [GO:0002717]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of TRAIL production [GO:0032759]; positive regulation of tumor necrosis factor production [GO:0032760]; protection from natural killer cell mediated cytotoxicity [GO:0042270]; regulation of natural killer cell mediated immunity [GO:0002715]" cell surface [GO:0009986]; early endosome membrane [GO:0031901]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; lumenal side of endoplasmic reticulum membrane [GO:0098553]; MHC class I protein complex [GO:0042612]; MHC class Ib protein complex [GO:0032398]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038] beta-2-microglobulin binding [GO:0030881]; MHC class I protein binding [GO:0042288]; natural killer cell lectin-like receptor binding [GO:0046703]; peptide antigen binding [GO:0042605]; signaling receptor binding [GO:0005102]; T cell receptor binding [GO:0042608] 0.86948 0.047397 AEWSDSAQGSESHSL 8.42366 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P13797 PLST_HUMAN Plastin-3 (T-plastin) PLS3 Homo sapiens (Human) actin filament bundle assembly [GO:0051017]; actin filament network formation [GO:0051639]; bone development [GO:0060348] actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886] actin filament binding [GO:0051015]; calcium ion binding [GO:0005509] 0.96307 -2.1539 EANMPLPGYKVR 0 10.5312 10.1021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P13804 ETFA_HUMAN "Electron transfer flavoprotein subunit alpha, mitochondrial (Alpha-ETF)" ETFA Homo sapiens (Human) amino acid catabolic process [GO:0009063]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; respiratory electron transport chain [GO:0022904] electron transfer flavoprotein complex [GO:0045251]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity [GO:0016491] 0.92654 -1.215 GLKSGENFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3465 0 0 0 10.0422 0 0 0 0 0 P13807 GYS1_HUMAN "Glycogen [starch] synthase, muscle (EC 2.4.1.11)" GYS1 GYS Homo sapiens (Human) glycogen biosynthetic process [GO:0005978]; heart development [GO:0007507] cytoplasm [GO:0005737]; cytosol [GO:0005829]; inclusion body [GO:0016234]; membrane [GO:0016020] "glucose binding [GO:0005536]; glycogen (starch) synthase activity [GO:0004373]; glycogen synthase activity, transferring glucose-1-phosphate [GO:0061547]; protein kinase binding [GO:0019901]" 0.88736 -0.36028 AIFATQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3716 0 0 0 0 0 0 0 9.8775 0 0 0 P13861 KAP2_HUMAN cAMP-dependent protein kinase type II-alpha regulatory subunit PRKAR2A PKR2 PRKAR2 Homo sapiens (Human) intracellular signal transduction [GO:0035556]; negative regulation of cAMP-dependent protein kinase activity [GO:2000480] cAMP-dependent protein kinase complex [GO:0005952]; centrosome [GO:0005813]; ciliary base [GO:0097546]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; protein-containing complex [GO:0032991] cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; cAMP-dependent protein kinase regulator activity [GO:0008603]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625] 0.96944 -3.1139 AASAYAVGDVK 11.1917 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.46932 0 0 0 0 P13929 ENOB_HUMAN Beta-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Enolase 3) (Muscle-specific enolase) (MSE) (Skeletal muscle enolase) ENO3 Homo sapiens (Human) canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886] magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634] 0.89038 -0.5016 AAVPSGASTGIYEALELR 10.399 0 10.3318 0 0 0 0 0 0 0 0 0 0 0 8.78718 0 0 0 0 0 0 8.89488 10.2277 0 0 0 0 P13942 COBA2_HUMAN Collagen alpha-2(XI) chain COL11A2 Homo sapiens (Human) cartilage development [GO:0051216]; collagen fibril organization [GO:0030199]; roof of mouth development [GO:0060021]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]; soft palate development [GO:0060023] collagen trimer [GO:0005581]; collagen type XI trimer [GO:0005592]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020]; metal ion binding [GO:0046872]; protein-macromolecule adaptor activity [GO:0030674] 0.95479 -1.5219 EEIEQMRRPTGTQDSPAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0611 0 0 0 P13945 ADRB3_HUMAN Beta-3 adrenergic receptor (Beta-3 adrenoreceptor) (Beta-3 adrenoceptor) ADRB3 ADRB3R B3AR Homo sapiens (Human) "activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; aging [GO:0007568]; brown fat cell differentiation [GO:0050873]; carbohydrate metabolic process [GO:0005975]; diet induced thermogenesis [GO:0002024]; eating behavior [GO:0042755]; energy reserve metabolic process [GO:0006112]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; generation of precursor metabolites and energy [GO:0006091]; heat generation [GO:0031649]; negative regulation of multicellular organism growth [GO:0040015]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of MAPK cascade [GO:0043410]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]" nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] beta-3 adrenergic receptor binding [GO:0031699]; beta-adrenergic receptor activity [GO:0004939]; beta3-adrenergic receptor activity [GO:0015052]; epinephrine binding [GO:0051379]; norepinephrine binding [GO:0051380]; protein homodimerization activity [GO:0042803] 0.95262 -1.4583 SSPAQPRLCQR 0 0 0 0 0 0 0 10.0307 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8438 10.7554 P13994 YJU2B_HUMAN Probable splicing factor YJU2B (Coiled-coil domain-containing protein 130) YJU2B CCDC130 SB115 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; response to virus [GO:0009615]; RNA splicing [GO:0008380]" post-mRNA release spliceosomal complex [GO:0071014]; U2-type spliceosomal complex [GO:0005684] 0.95306 -1.4869 ASLTIPLVPETEDDRK 0 0 0 0 0 0 0 0 0 9.84145 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P14061 DHB1_HUMAN 17-beta-hydroxysteroid dehydrogenase type 1 (17-beta-HSD 1) (EC 1.1.1.51) (20 alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH) (Estradiol 17-beta-dehydrogenase 1) (EC 1.1.1.62) (Placental 17-beta-hydroxysteroid dehydrogenase) (Short chain dehydrogenase/reductase family 28C member 1) HSD17B1 E17KSR EDH17B1 EDH17B2 EDHB17 SDR28C1 Homo sapiens (Human) adipose tissue development [GO:0060612]; bone development [GO:0060348]; cellular response to metal ion [GO:0071248]; estrogen biosynthetic process [GO:0006703]; estrogen metabolic process [GO:0008210]; gene expression [GO:0010467]; lysosome organization [GO:0007040]; skeletal muscle tissue development [GO:0007519]; steroid biosynthetic process [GO:0006694]; testosterone biosynthetic process [GO:0061370] cytoplasm [GO:0005737]; cytosol [GO:0005829] 17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; 17-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0072582]; catalytic activity [GO:0003824]; dihydrotestosterone 17-beta-dehydrogenase activity [GO:0035410]; estradiol 17-beta-dehydrogenase [NAD(P)] activity [GO:0004303]; estradiol binding [GO:1903924]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; steroid binding [GO:0005496]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]; testosterone dehydrogenase (NAD+) activity [GO:0047035]; testosterone dehydrogenase [NAD(P)] activity [GO:0030283] 0.81116 0.22472 EVFGDVPAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6584 0 0 0 0 0 0 0 0 P14091 CATE_HUMAN Cathepsin E (EC 3.4.23.34) [Cleaved into: Cathepsin E form I; Cathepsin E form II] CTSE Homo sapiens (Human) antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508] endosome [GO:0005768]; intracellular membrane-bounded organelle [GO:0043231] aspartic-type endopeptidase activity [GO:0004190]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233] 0.66199 0.39471 VGLAPAVP 11.4013 11.4891 11.3735 12.3525 12.5785 12.428 11.5309 11.4359 11.4688 14.0764 14.1114 14.0144 12.9483 12.6272 12.9622 11.22 10.5196 10.59 12.6191 12.754 12.7422 12.7826 12.8084 12.7234 11.2324 10.4766 10.3 P14174 MIF_HUMAN Macrophage migration inhibitory factor (MIF) (EC 5.3.2.1) (Glycosylation-inhibiting factor) (GIF) (L-dopachrome isomerase) (L-dopachrome tautomerase) (EC 5.3.3.12) (Phenylpyruvate tautomerase) MIF GLIF MMIF Homo sapiens (Human) "carboxylic acid metabolic process [GO:0019752]; cell surface receptor signaling pathway [GO:0007166]; cellular senescence [GO:0090398]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular senescence [GO:2000773]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; negative regulation of protein metabolic process [GO:0051248]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine production [GO:0001819]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]" cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982] chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020] 0.059184 1.3512 IGGAQNR 0 0 0 0 0 0 0 0 8.52337 0 0 0 0 9.05509 0 0 0 0 0 0 9.52939 0 0 0 0 0 0 P14210 HGF_HUMAN Hepatocyte growth factor (Hepatopoietin-A) (Scatter factor) (SF) [Cleaved into: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain] HGF HPTA Homo sapiens (Human) animal organ regeneration [GO:0031100]; cell chemotaxis [GO:0060326]; cell morphogenesis [GO:0000902]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; epithelial cell proliferation [GO:0050673]; epithelial to mesenchymal transition [GO:0001837]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; liver development [GO:0001889]; mitotic cell cycle [GO:0000278]; myoblast proliferation [GO:0051450]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of hydrogen peroxide-mediated programmed cell death [GO:1901299]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of myelination [GO:0031643]; positive regulation of neuron projection regeneration [GO:0070572]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling [GO:0060665]; regulation of p38MAPK cascade [GO:1900744]; regulation of tau-protein kinase activity [GO:1902947]; skeletal muscle cell proliferation [GO:0014856] extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093] chemoattractant activity [GO:0042056]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102] 0.8191 0.21876 HIFWEPDASK 0 9.32868 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P14222 PERF_HUMAN Perforin-1 (P1) (Cytolysin) (Lymphocyte pore-forming protein) (PFP) PRF1 PFP Homo sapiens (Human) apoptotic process [GO:0006915]; cellular defense response [GO:0006968]; defense response to tumor cell [GO:0002357]; defense response to virus [GO:0051607]; granzyme-mediated programmed cell death signaling pathway [GO:0140507]; immune response to tumor cell [GO:0002418]; immunological synapse formation [GO:0001771]; killing of cells of another organism [GO:0031640]; positive regulation of killing of cells of another organism [GO:0051712]; protein homooligomerization [GO:0051260]; protein import [GO:0017038]; protein secretion [GO:0009306]; protein transmembrane transport [GO:0071806]; T cell mediated cytotoxicity [GO:0001913] cytolytic granule [GO:0044194]; cytosol [GO:0005829]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; immunological synapse [GO:0001772]; membrane [GO:0016020]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; pore-forming activity [GO:0140911]; wide pore channel activity [GO:0022829] 0.56307 0.51269 LISNYGTHFIR 0 0 10.2819 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.2747 0 0 0 0 P14314 GLU2B_HUMAN Glucosidase 2 subunit beta (80K-H protein) (Glucosidase II subunit beta) (Protein kinase C substrate 60.1 kDa protein heavy chain) (PKCSH) PRKCSH G19P1 Homo sapiens (Human) intracellular signal transduction [GO:0035556]; liver development [GO:0001889]; N-glycan processing [GO:0006491] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; glucosidase II complex [GO:0017177]; intracellular membrane-bounded organelle [GO:0043231] calcium ion binding [GO:0005509]; phosphoprotein binding [GO:0051219]; protein kinase C binding [GO:0005080]; transmembrane transporter binding [GO:0044325] 0 18.716 AQQEQELAADAFK 9.27226 9.3768 10.6247 0 0 0 10.7292 0 9.39898 10.5412 0 9.48055 8.97292 9.18197 9.52964 0 0 0 10.5269 0 0 9.85293 10.9309 10.8203 11.5419 12.4616 12.3474 P14317 HCLS1_HUMAN Hematopoietic lineage cell-specific protein (Hematopoietic cell-specific LYN substrate 1) (LckBP1) (p75) HCLS1 HS1 Homo sapiens (Human) actin filament organization [GO:0007015]; cellular response to cytokine stimulus [GO:0071345]; erythrocyte differentiation [GO:0030218]; intracellular signal transduction [GO:0035556]; negative regulation of leukocyte apoptotic process [GO:2000107]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of actin filament polymerization [GO:0030833]; regulation of DNA-templated transcription [GO:0006355]; response to hormone [GO:0009725]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle [GO:0030139]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; transcription regulator complex [GO:0005667] actin filament binding [GO:0051015]; protein kinase binding [GO:0019901]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; SH3 domain binding [GO:0017124] 0.964 -2.2159 AKFESMAEEK 0 0 0 0 0 0 9.93201 10.1848 0 0 0 0 0 0 0 0 0 0 0 0 10.5469 0 0 0 0 0 0 P14324 FPPS_HUMAN "Farnesyl pyrophosphate synthase (FPP synthase) (FPS) (EC 2.5.1.10) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Geranyltranstransferase)" FDPS FPS KIAA1293 Homo sapiens (Human) cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654] dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723] 0 5.0708 ATPEQYQILK 11.0998 10.9273 10.9465 0 0 0 11.18 11.7462 11.8177 0 0 0 9.60986 0 0 0 0 10.2928 0 0 0 0 0 9.67354 0 0 0 P14373 TRI27_HUMAN Zinc finger protein RFP (EC 2.3.2.27) (RING finger protein 76) (Ret finger protein) (Tripartite motif-containing protein 27) TRIM27 RFP RNF76 Homo sapiens (Human) "Arp2/3 complex-mediated actin nucleation [GO:0034314]; innate immune response [GO:0045087]; negative regulation of adaptive immune response [GO:0002820]; negative regulation of autophagy [GO:0010507]; negative regulation of calcium ion import [GO:0090281]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral transcription [GO:0032897]; positive regulation of actin nucleation [GO:0051127]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of type II interferon production [GO:0032729]; protein K63-linked ubiquitination [GO:0070534]; protein sumoylation [GO:0016925]; retrograde transport, endosome to Golgi [GO:0042147]; spermatogenesis [GO:0007283]; suppression of viral release by host [GO:0044790]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; fibrillar center [GO:0001650]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605] DNA binding [GO:0003677]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; SUMO transferase activity [GO:0019789]; transcription coactivator activity [GO:0003713]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.92245 -0.94285 AQGEQAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.71959 0 0 0 0 0 0 P14384 CBPM_HUMAN Carboxypeptidase M (CPM) (EC 3.4.17.12) CPM Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; peptide metabolic process [GO:0006518]; protein processing [GO:0016485] cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] carboxypeptidase activity [GO:0004180]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270] 0.96974 -3.2625 EHRIGIPEFK 0 0 0 9.94875 0 0 0 0 0 0 0 0 0 0 0 10.0558 0 8.62757 0 0 0 0 0 0 10.2655 0 0 P14410 SUIS_HUMAN "Sucrase-isomaltase, intestinal [Cleaved into: Sucrase (EC 3.2.1.48); Isomaltase (EC 3.2.1.10)]" SI Homo sapiens (Human) polysaccharide digestion [GO:0044245]; sucrose catabolic process [GO:0005987] apical plasma membrane [GO:0016324]; brush border [GO:0005903]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886] "alpha-1,4-glucosidase activity [GO:0004558]; carbohydrate binding [GO:0030246]; oligo-1,6-glucosidase activity [GO:0004574]; sucrose alpha-glucosidase activity [GO:0004575]" 0.95202 -1.3864 EIVDFYNEKMK 11.6241 0 11.4261 0 10.097 0 0 0 11.6573 0 0 0 0 0 0 11.3989 11.388 0 0 0 0 0 0 0 0 0 0 P14416 DRD2_HUMAN D(2) dopamine receptor (Dopamine D2 receptor) DRD2 Homo sapiens (Human) "acid secretion [GO:0046717]; activation of protein kinase activity [GO:0032147]; adenohypophysis development [GO:0021984]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; adult walking behavior [GO:0007628]; arachidonic acid secretion [GO:0050482]; associative learning [GO:0008306]; auditory behavior [GO:0031223]; autophagy [GO:0006914]; axonogenesis [GO:0007409]; behavioral response to cocaine [GO:0048148]; behavioral response to ethanol [GO:0048149]; branching morphogenesis of a nerve [GO:0048755]; cerebral cortex GABAergic interneuron migration [GO:0021853]; circadian regulation of gene expression [GO:0032922]; dopamine metabolic process [GO:0042417]; dopamine uptake involved in synaptic transmission [GO:0051583]; drinking behavior [GO:0042756]; epithelial cell proliferation [GO:0050673]; excitatory postsynaptic potential [GO:0060079]; G protein-coupled receptor internalization [GO:0002031]; grooming behavior [GO:0007625]; hyaloid vascular plexus regression [GO:1990384]; intracellular calcium ion homeostasis [GO:0006874]; intracellular signal transduction [GO:0035556]; locomotory behavior [GO:0007626]; long-term memory [GO:0007616]; negative regulation of adenylate cyclase activity [GO:0007194]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell death [GO:0060548]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of circadian sleep/wake cycle, sleep [GO:0042321]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of dopamine receptor signaling pathway [GO:0060160]; negative regulation of dopamine secretion [GO:0033602]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of innate immune response [GO:0045824]; negative regulation of insulin secretion [GO:0046676]; negative regulation of neuron migration [GO:2001223]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein secretion [GO:0050709]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; negative regulation of voltage-gated calcium channel activity [GO:1901386]; nervous system process involved in regulation of systemic arterial blood pressure [GO:0001976]; neuroblast proliferation [GO:0007405]; neuron-neuron synaptic transmission [GO:0007270]; orbitofrontal cortex development [GO:0021769]; peristalsis [GO:0030432]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; pigmentation [GO:0043473]; positive regulation of cytokinesis [GO:0032467]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of dopamine uptake involved in synaptic transmission [GO:0051586]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glial cell-derived neurotrophic factor production [GO:1900168]; positive regulation of growth hormone secretion [GO:0060124]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of receptor internalization [GO:0002092]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of urine volume [GO:0035810]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; prepulse inhibition [GO:0060134]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein kinase B signaling [GO:0043491]; protein localization [GO:0008104]; regulation of dopamine uptake involved in synaptic transmission [GO:0051584]; regulation of heart rate [GO:0002027]; regulation of locomotion involved in locomotory behavior [GO:0090325]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of phosphoprotein phosphatase activity [GO:0043666]; regulation of potassium ion transport [GO:0043266]; regulation of sodium ion transport [GO:0002028]; regulation of synapse structural plasticity [GO:0051823]; regulation of synaptic transmission, GABAergic [GO:0032228]; release of sequestered calcium ion into cytosol [GO:0051209]; response to amphetamine [GO:0001975]; response to axon injury [GO:0048678]; response to cocaine [GO:0042220]; response to histamine [GO:0034776]; response to hypoxia [GO:0001666]; response to inactivity [GO:0014854]; response to iron ion [GO:0010039]; response to light stimulus [GO:0009416]; response to morphine [GO:0043278]; response to nicotine [GO:0035094]; response to toxic substance [GO:0009636]; response to xenobiotic stimulus [GO:0009410]; sensory perception of smell [GO:0007608]; striatum development [GO:0021756]; synapse assembly [GO:0007416]; temperature homeostasis [GO:0001659]; visual learning [GO:0008542]; Wnt signaling pathway [GO:0016055]" acrosomal vesicle [GO:0001669]; axon [GO:0030424]; axon terminus [GO:0043679]; ciliary membrane [GO:0060170]; cilium [GO:0005929]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; dopaminergic synapse [GO:0098691]; endocytic vesicle [GO:0030139]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; lateral plasma membrane [GO:0016328]; non-motile cilium [GO:0097730]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; sperm flagellum [GO:0036126]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672] "dopamine binding [GO:0035240]; dopamine neurotransmitter receptor activity, coupled via Gi/Go [GO:0001591]; G protein-coupled receptor activity [GO:0004930]; heterocyclic compound binding [GO:1901363]; identical protein binding [GO:0042802]; ionotropic glutamate receptor binding [GO:0035255]; potassium channel regulator activity [GO:0015459]; protein-containing complex binding [GO:0044877]" 0.86999 0.056227 IFEIQTMPNGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0088 0 0 0 0 0 0 0 P14543 NID1_HUMAN Nidogen-1 (NID-1) (Entactin) NID1 NID Homo sapiens (Human) basement membrane organization [GO:0071711]; canonical Wnt signaling pathway [GO:0060070]; cell-matrix adhesion [GO:0007160]; glomerular basement membrane development [GO:0032836]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of basement membrane organization [GO:0110011] basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; protein complex involved in cell-matrix adhesion [GO:0098637] calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; extracellular matrix structural constituent [GO:0005201]; laminin binding [GO:0043236]; laminin-1 binding [GO:0043237]; proteoglycan binding [GO:0043394]; Wnt receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147] 0 45.882 ASLHGGEPTTIIR 12.1185 12.7217 12.562 10.5702 10.5792 10.5593 11.6621 0 11.5208 12.2843 13.594 10.594 10.5047 11.3017 11.2044 0 11.4399 10.3138 9.91681 9.11858 11.0185 0 0 0 10.3809 10.2837 0 P14550 AK1A1_HUMAN Aldo-keto reductase family 1 member A1 (EC 1.1.1.2) (EC 1.1.1.372) (EC 1.1.1.54) (Alcohol dehydrogenase [NADP(+)]) (Aldehyde reductase) (Glucuronate reductase) (EC 1.1.1.19) (Glucuronolactone reductase) (EC 1.1.1.20) AKR1A1 ALDR1 ALR Homo sapiens (Human) aldehyde catabolic process [GO:0046185]; cellular detoxification of aldehyde [GO:0110095]; D-glucuronate catabolic process [GO:0042840]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; glucuronate catabolic process to xylulose 5-phosphate [GO:0019640]; glutathione derivative biosynthetic process [GO:1901687]; L-ascorbic acid biosynthetic process [GO:0019853]; lipid metabolic process [GO:0006629] apical plasma membrane [GO:0016324]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; synapse [GO:0045202] "alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; allyl-alcohol dehydrogenase activity [GO:0047655]; glucuronolactone reductase activity [GO:0047941]; glycerol dehydrogenase [NADP+] activity [GO:0047956]; L-glucuronate reductase activity [GO:0047939]; methylglyoxal reductase (NADPH-dependent, acetol producing) [GO:1990002]; oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor [GO:0016657]" 0.0059524 2.4399 AASCVLLHTGQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.74618 0 0 9.08619 0 9.07759 0 0 9.01293 10.1762 9.72207 9.81559 P14555 PA2GA_HUMAN "Phospholipase A2, membrane associated (EC 3.1.1.4) (GIIC sPLA2) (Group IIA phospholipase A2) (Non-pancreatic secretory phospholipase A2) (NPS-PLA2) (Phosphatidylcholine 2-acylhydrolase 2A)" PLA2G2A PLA2B PLA2L RASF-A Homo sapiens (Human) arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; intestinal stem cell homeostasis [GO:0036335]; killing of cells of another organism [GO:0031640]; lipid catabolic process [GO:0016042]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of T cell proliferation [GO:0042130]; phosphatidic acid metabolic process [GO:0046473]; phosphatidylcholine metabolic process [GO:0046470]; phosphatidylethanolamine metabolic process [GO:0046337]; phospholipid metabolic process [GO:0006644]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response [GO:0050729]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; regulation of neutrophil activation [GO:1902563] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141] calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; phospholipase A2 activity [GO:0004623]; phospholipid binding [GO:0005543] 0.88241 -0.084459 TTYNKKYQYYSNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.54114 0 0 0 0 0 0 0 P14616 INSRR_HUMAN Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] INSRR IRR Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; cellular response to alkaline pH [GO:0071469]; male sex determination [GO:0030238]; positive regulation of kinase activity [GO:0033674]; protein autophosphorylation [GO:0046777]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] axon [GO:0030424]; insulin receptor complex [GO:0005899]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] ATP binding [GO:0005524]; insulin receptor activity [GO:0005009]; insulin receptor substrate binding [GO:0043560]; phosphatidylinositol 3-kinase binding [GO:0043548]; transmembrane receptor protein tyrosine kinase activity [GO:0004714] 0.87038 0.03454 AVLSGLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3012 0 0 0 0 0 0 0 0 0 P14618 KPYM_HUMAN Pyruvate kinase PKM (EC 2.7.1.40) (Cytosolic thyroid hormone-binding protein) (CTHBP) (Opa-interacting protein 3) (OIP-3) (Pyruvate kinase 2/3) (Pyruvate kinase muscle isozyme) (Threonine-protein kinase PKM2) (EC 2.7.11.1) (Thyroid hormone-binding protein 1) (THBP1) (Tumor M2-PK) (Tyrosine-protein kinase PKM2) (EC 2.7.10.2) (p58) PKM OIP3 PK2 PK3 PKM2 Homo sapiens (Human) canonical glycolysis [GO:0061621]; cellular response to insulin stimulus [GO:0032869]; glycolytic process [GO:0006096]; phosphorylation [GO:0016310]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; programmed cell death [GO:0012501] cilium [GO:0005929]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular vesicle [GO:1903561]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; rough endoplasmic reticulum [GO:0005791]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982] ATP binding [GO:0005524]; cadherin binding [GO:0045296]; histone H3T11 kinase activity [GO:0035402]; magnesium ion binding [GO:0000287]; MHC class II protein complex binding [GO:0023026]; mRNA binding [GO:0003729]; potassium ion binding [GO:0030955]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; pyruvate kinase activity [GO:0004743]; RNA binding [GO:0003723]; transcription coactivator activity [GO:0003713] 0 181.07 APIIAVTR 12.8055 13.0826 13.2607 11.0086 10.5941 10.4402 14.8431 14.3822 14.5741 12.8799 13.2298 12.7997 12.8726 11.8467 13.0525 13.688 12.7951 13.2702 11.9846 12.4372 11.9919 11.7085 11.9477 11.5903 14.643 14.3396 13.7957 P14625 ENPL_HUMAN Endoplasmin (94 kDa glucose-regulated protein) (GRP-94) (Heat shock protein 90 kDa beta member 1) (Tumor rejection antigen 1) (gp96 homolog) HSP90B1 GRP94 TRA1 Homo sapiens (Human) "actin rod assembly [GO:0031247]; cellular response to ATP [GO:0071318]; negative regulation of apoptotic process [GO:0043066]; protein folding [GO:0006457]; protein folding in endoplasmic reticulum [GO:0034975]; protein transport [GO:0015031]; regulation of phosphoprotein phosphatase activity [GO:0043666]; response to endoplasmic reticulum stress [GO:0034976]; response to hypoxia [GO:0001666]; retrograde protein transport, ER to cytosol [GO:0030970]; sequestering of calcium ion [GO:0051208]; ubiquitin-dependent ERAD pathway [GO:0030433]" collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endocytic vesicle lumen [GO:0071682]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; sarcoplasmic reticulum lumen [GO:0033018]; sperm plasma membrane [GO:0097524] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; calcium ion binding [GO:0005509]; low-density lipoprotein particle receptor binding [GO:0050750]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082] 0 196.92 DISTNYYASQK 12.6824 12.2864 12.3349 0 9.59939 8.55117 12.8592 12.9672 12.9564 13.0921 13.3204 12.8191 12.1096 12.2378 12.3242 12.5702 12.8513 12.1045 14.7208 14.1387 14.5038 13.7187 13.8336 13.6104 15.4997 15.2215 15.416 P14635 CCNB1_HUMAN G2/mitotic-specific cyclin-B1 CCNB1 CCNB Homo sapiens (Human) cell division [GO:0051301]; G2/M transition of mitotic cell cycle [GO:0000086]; in utero embryonic development [GO:0001701]; mitotic cell cycle phase transition [GO:0044772]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle organization [GO:0007052]; positive regulation of attachment of spindle microtubules to kinetochore [GO:0051987]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of mitochondrial ATP synthesis coupled electron transport [GO:1905448]; positive regulation of mitotic cell cycle [GO:0045931]; protein phosphorylation [GO:0006468]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090266] centrosome [GO:0005813]; cyclin B1-CDK1 complex [GO:0097125]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; outer kinetochore [GO:0000940]; spindle pole [GO:0000922] cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; molecular adaptor activity [GO:0060090]; patched binding [GO:0005113]; protein kinase binding [GO:0019901]; ubiquitin-like protein ligase binding [GO:0044389] 0.9534 -1.4878 YATSKHAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8118 0 0 0 0 0 0 0 0 0 0 P14649 MYL6B_HUMAN Myosin light chain 6B (Myosin light chain 1 slow-twitch muscle A isoform) (MLC1sa) (Smooth muscle and nonmuscle myosin light chain alkali 6B) MYL6B MLC1SA Homo sapiens (Human) muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; skeletal muscle tissue development [GO:0007519] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; muscle myosin complex [GO:0005859]; myosin complex [GO:0016459]; myosin II complex [GO:0016460]; unconventional myosin complex [GO:0016461] calcium ion binding [GO:0005509]; cytoskeletal motor activity [GO:0003774]; structural constituent of muscle [GO:0008307] 0 10.663 ALGQNPTNAEVLK 10.0181 10.1694 10.1861 12.5268 0 0 10.3009 10.4951 10.6057 9.48271 9.44035 9.57539 13.9909 13.2483 0 0 0 0 0 10.5025 0 0 10.1739 0 0 0 0 P14679 TYRO_HUMAN Tyrosinase (EC 1.14.18.1) (LB24-AB) (Monophenol monooxygenase) (SK29-AB) (Tumor rejection antigen AB) TYR Homo sapiens (Human) cell population proliferation [GO:0008283]; eye pigment biosynthetic process [GO:0006726]; melanin biosynthetic process [GO:0042438]; melanin biosynthetic process from tyrosine [GO:0006583]; pigmentation [GO:0043473]; response to blue light [GO:0009637]; response to cAMP [GO:0051591]; response to UV [GO:0009411]; response to vitamin D [GO:0033280]; thymus development [GO:0048538]; visual perception [GO:0007601] cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi-associated vesicle [GO:0005798]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; melanosome [GO:0042470]; melanosome membrane [GO:0033162]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; tyrosinase activity [GO:0004503] 0.89965 -0.69036 ACVSSKNLMEK 10.8723 10.5091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P14735 IDE_HUMAN Insulin-degrading enzyme (EC 3.4.24.56) (Abeta-degrading protease) (Insulin protease) (Insulinase) (Insulysin) IDE Homo sapiens (Human) amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta metabolic process [GO:0050435]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; bradykinin catabolic process [GO:0010815]; hormone catabolic process [GO:0042447]; insulin catabolic process [GO:1901143]; insulin metabolic process [GO:1901142]; insulin receptor signaling pathway [GO:0008286]; peptide catabolic process [GO:0043171]; positive regulation of protein binding [GO:0032092]; positive regulation of protein catabolic process [GO:0045732]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of aerobic respiration [GO:1903715]; ubiquitin recycling [GO:0010992] basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777] ATP binding [GO:0005524]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; insulin binding [GO:0043559]; metalloendopeptidase activity [GO:0004222]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ubiquitin-dependent protein binding [GO:0140036]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270] 0.9594 -1.7407 ESLDDLTNLVVK 0 0 10.4952 0 0 0 0 9.60563 0 12.341 11.7518 12.4983 0 0 0 0 0 0 8.99808 9.2174 0 0 0 0 0 0 0 P14780 MMP9_HUMAN Matrix metalloproteinase-9 (MMP-9) (EC 3.4.24.35) (92 kDa gelatinase) (92 kDa type IV collagenase) (Gelatinase B) (GELB) [Cleaved into: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9] MMP9 CLG4B Homo sapiens (Human) apoptotic process [GO:0006915]; cell migration [GO:0016477]; cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV-A [GO:0071492]; collagen catabolic process [GO:0030574]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501] collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724] collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270] 0.96214 -2.0352 EKAYFCQDR 0 0 0 0 8.54392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P14866 HNRPL_HUMAN Heterogeneous nuclear ribonucleoprotein L (hnRNP L) HNRNPL HNRPL P/OKcl.14 Homo sapiens (Human) "cellular response to amino acid starvation [GO:0034198]; circadian rhythm [GO:0007623]; mRNA processing [GO:0006397]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of mRNA binding [GO:1902416]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of RNA splicing [GO:0043484]; response to peptide [GO:1901652]; RNA processing [GO:0006396]" chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribonucleoprotein complex [GO:1990904]; ribonucleoprotein granule [GO:0035770] mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; mRNA CDS binding [GO:1990715]; pre-mRNA intronic binding [GO:0097157]; RNA binding [GO:0003723]; transcription cis-regulatory region binding [GO:0000976] 0.018824 1.6506 AITHLNNNFMFGQK 0 0 0 0 0 0 0 9.18824 9.02826 0 9.40829 10.0031 9.6841 0 0 10.0091 0 0 0 10.4524 0 0 0 0 0 0 8.70366 P14868 SYDC_HUMAN "Aspartate--tRNA ligase, cytoplasmic (EC 6.1.1.12) (Aspartyl-tRNA synthetase) (AspRS) (Cell proliferation-inducing gene 40 protein)" DARS1 DARS PIG40 Homo sapiens (Human) aspartyl-tRNA aminoacylation [GO:0006422]; protein-containing complex assembly [GO:0065003]; translation [GO:0006412] aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; synapse [GO:0045202] aminoacylase activity [GO:0004046]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; RNA binding [GO:0003723] 0.050955 1.4294 EIMDAAEDYAKER 0 0 0 0 0 0 9.69688 0 0 0 0 10.5139 0 0 8.97885 0 9.5125 0 0 0 0 0 0 0 0 0 0 P14902 I23O1_HUMAN "Indoleamine 2,3-dioxygenase 1 (IDO-1) (EC 1.13.11.52) (Indoleamine-pyrrole 2,3-dioxygenase)" IDO1 IDO INDO Homo sapiens (Human) 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; kynurenic acid biosynthetic process [GO:0034276]; multicellular organismal response to stress [GO:0033555]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell apoptotic process [GO:0070233]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of chronic inflammatory response [GO:0002678]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of T cell apoptotic process [GO:0070234]; positive regulation of T cell tolerance induction [GO:0002666]; positive regulation of type 2 immune response [GO:0002830]; response to lipopolysaccharide [GO:0032496]; swimming behavior [GO:0036269]; T cell proliferation [GO:0042098]; tryptophan catabolic process [GO:0006569]; tryptophan catabolic process to kynurenine [GO:0019441] cytoplasm [GO:0005737]; cytosol [GO:0005829]; smooth muscle contractile fiber [GO:0030485]; stereocilium bundle [GO:0032421] "electron transfer activity [GO:0009055]; heme binding [GO:0020037]; indoleamine 2,3-dioxygenase activity [GO:0033754]; metal ion binding [GO:0046872]; tryptophan 2,3-dioxygenase activity [GO:0004833]" 0.90062 -0.69199 LVLGCITMAYVWGK 8.93508 9.1243 0 0 0 0 0 0 0 0 0 0 9.33514 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P14921 ETS1_HUMAN Protein C-ets-1 (p54) ETS1 EWSR2 Homo sapiens (Human) cell motility [GO:0048870]; immune response [GO:0006955]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; transcription by RNA polymerase II [GO:0006366] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; nuclear receptor coactivator activity [GO:0030374]; nucleic acid binding [GO:0003676]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription cis-regulatory region binding [GO:0000976]; transcription corepressor binding [GO:0001222]" 0.96368 -2.2507 GLRYYYDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1473 0 0 0 0 0 0 0 0 11.2165 0 P14923 PLAK_HUMAN Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3) JUP CTNNG DP3 Homo sapiens (Human) bundle of His cell-Purkinje myocyte adhesion involved in cell communication [GO:0086073]; canonical Wnt signaling pathway [GO:0060070]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cellular response to indole-3-methanol [GO:0071681]; desmosome assembly [GO:0002159]; detection of mechanical stimulus [GO:0050982]; endothelial cell-cell adhesion [GO:0071603]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; positive regulation of angiogenesis [GO:0045766]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; regulation of cell population proliferation [GO:0042127]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; skin development [GO:0043588] actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; catenin complex [GO:0016342]; cell-cell junction [GO:0005911]; cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; desmosome [GO:0030057]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; fascia adherens [GO:0005916]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; gamma-catenin-TCF7L2 complex [GO:0071665]; intercalated disc [GO:0014704]; intermediate filament [GO:0005882]; lateral plasma membrane [GO:0016328]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-DNA complex [GO:0032993]; specific granule lumen [GO:0035580]; Z disc [GO:0030018]; zonula adherens [GO:0005915] alpha-catenin binding [GO:0045294]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication [GO:0086083]; cytoskeletal protein-membrane anchor activity [GO:0106006]; DNA-binding transcription factor binding [GO:0140297]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; protein-containing complex binding [GO:0044877]; structural molecule activity [GO:0005198]; transcription coactivator activity [GO:0003713] 0 5.9253 ALMGSPQLVAAVVR 0 0 0 0 0 0 0 0 0 9.39043 0 0 0 0 0 10.8415 0 0 0 0 0 0 0 0 0 9.59025 8.1822 P15104 GLNA_HUMAN Glutamine synthetase (GS) (EC 6.3.1.2) (Glutamate--ammonia ligase) (Palmitoyltransferase GLUL) (EC 2.3.1.225) GLUL GLNS Homo sapiens (Human) "ammonia assimilation cycle [GO:0019676]; angiogenesis [GO:0001525]; cell population proliferation [GO:0008283]; cellular response to starvation [GO:0009267]; glutamate catabolic process [GO:0006538]; glutamine biosynthetic process [GO:0006542]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of insulin secretion [GO:0032024]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; protein palmitoylation [GO:0018345]; regulation of endothelial cell migration [GO:0010594]; regulation of protein localization to nucleolus [GO:1904749]; regulation of sprouting angiogenesis [GO:1903670]; response to glucose [GO:0009749]; ribosome biogenesis [GO:0042254]" axon terminus [GO:0043679]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glial cell projection [GO:0097386]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; rough endoplasmic reticulum [GO:0005791] ATP binding [GO:0005524]; dynein light chain binding [GO:0045503]; glutamate binding [GO:0016595]; glutamate-ammonia ligase activity [GO:0004356]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; protein-cysteine S-palmitoyltransferase activity [GO:0019706] 0.94009 -1.3018 SASIRIPR 0 0 0 0 0 0 0 0 0 0 0 13.7732 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P15121 ALDR_HUMAN Aldo-keto reductase family 1 member B1 (EC 1.1.1.300) (EC 1.1.1.372) (EC 1.1.1.54) (Aldehyde reductase) (Aldose reductase) (AR) (EC 1.1.1.21) AKR1B1 ALDR1 ALR2 Homo sapiens (Human) C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; epithelial cell maturation [GO:0002070]; fructose biosynthetic process [GO:0046370]; L-ascorbic acid biosynthetic process [GO:0019853]; metanephric collecting duct development [GO:0072205]; negative regulation of apoptotic process [GO:0043066]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; retinoid metabolic process [GO:0001523] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654] alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; glycerol dehydrogenase [NADP+] activity [GO:0047956]; L-glucuronate reductase activity [GO:0047939]; NADP-retinol dehydrogenase activity [GO:0052650]; prostaglandin H2 endoperoxidase reductase activity [GO:0036130]; retinal dehydrogenase activity [GO:0001758] 0.063872 1.3002 SPPGQVTEAVK 0 0 0 0 0 0 0 0 0 9.34503 10.0256 0 0 0 0 9.39684 0 0 0 0 0 0 0 0 0 0 10.793 P15144 AMPN_HUMAN Aminopeptidase N (AP-N) (hAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (Myeloid plasma membrane glycoprotein CD13) (gp150) (CD antigen CD13) ANPEP APN CD13 PEPN Homo sapiens (Human) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667] aminopeptidase activity [GO:0004177]; metalloaminopeptidase activity [GO:0070006]; metallopeptidase activity [GO:0008237]; peptide binding [GO:0042277]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270] 0.92975 -1.2423 ALEQALEK 0 0 0 0 0 0 9.87787 0 0 0 0 0 9.30195 0 0 0 0 0 0 0 0 0 9.56564 0 0 0 0 P15170 ERF3A_HUMAN Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Eukaryotic peptide chain release factor subunit 3a) (eRF3a) (EC 3.6.5.-) (G1 to S phase transition protein 1 homolog) GSPT1 ERF3A Homo sapiens (Human) "G1/S transition of mitotic cell cycle [GO:0000082]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; protein methylation [GO:0006479]; regulation of translational termination [GO:0006449]; translation [GO:0006412]; translational termination [GO:0006415]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; translation release factor complex [GO:0018444] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; molecular function activator activity [GO:0140677]; RNA binding [GO:0003723]; translation release factor activity [GO:0003747] 0.88485 -0.20399 EHAMLAK 0 8.96821 0 0 0 0 0 0 0 0 0 0 0 0 9.84347 0 0 0 0 0 0 0 0 0 0 0 0 P15172 MYOD1_HUMAN Myoblast determination protein 1 (Class C basic helix-loop-helix protein 1) (bHLHc1) (Myogenic factor 3) (Myf-3) MYOD1 BHLHC1 MYF3 MYOD Homo sapiens (Human) "cellular response to estradiol stimulus [GO:0071392]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to oxygen levels [GO:0071453]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; muscle cell fate commitment [GO:0042693]; muscle organ development [GO:0007517]; myoblast fate determination [GO:0007518]; myoblast fusion [GO:0007520]; myotube cell development [GO:0014904]; myotube differentiation involved in skeletal muscle regeneration [GO:0014908]; negative regulation of chromatin binding [GO:0035562]; negative regulation of myoblast proliferation [GO:2000818]; positive regulation of binding [GO:0051099]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of skeletal muscle fiber development [GO:0048743]; positive regulation of skeletal muscle tissue regeneration [GO:0043415]; positive regulation of snRNA transcription by RNA polymerase II [GO:1905382]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of RNA splicing [GO:0043484]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal muscle cell differentiation [GO:0035914]; skeletal muscle fiber adaptation [GO:0043503]; skeletal muscle fiber development [GO:0048741]; skeletal muscle tissue development [GO:0007519]; transcription by RNA polymerase II [GO:0006366]" chromatin [GO:0000785]; euchromatin [GO:0000791]; myofibril [GO:0030016]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "bHLH transcription factor binding [GO:0043425]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; E-box binding [GO:0070888]; nuclear receptor binding [GO:0016922]; promoter-specific chromatin binding [GO:1990841]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific double-stranded DNA binding [GO:1990837]; ubiquitin protein ligase binding [GO:0031625]" 0.91573 -0.77262 KTTNADRR 8.71177 8.51704 8.70722 0 0 0 0 8.91187 8.83333 0 0 0 0 0 0 0 0 0 10.6584 0 0 0 0 0 0 0 0 P15260 INGR1_HUMAN Interferon gamma receptor 1 (IFN-gamma receptor 1) (IFN-gamma-R1) (CDw119) (Interferon gamma receptor alpha-chain) (IFN-gamma-R-alpha) (CD antigen CD119) IFNGR1 Homo sapiens (Human) astrocyte activation [GO:0048143]; cellular response to virus [GO:0098586]; microglial cell activation [GO:0001774]; negative regulation of amyloid-beta clearance [GO:1900222]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of gene expression [GO:0010628]; positive regulation of tumor necrosis factor production [GO:0032760]; response to virus [GO:0009615]; signal transduction [GO:0007165]; type II interferon-mediated signaling pathway [GO:0060333]; type III interferon-mediated signaling pathway [GO:0038196] membrane [GO:0016020]; plasma membrane [GO:0005886] cytokine binding [GO:0019955]; type II interferon receptor activity [GO:0004906] 0.95257 -1.4548 VGQKESAYAK 0 0 0 0 0 0 0 8.99611 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.56522 0 0 0 P15309 PPAP_HUMAN Prostatic acid phosphatase (PAP) (EC 3.1.3.2) (5'-nucleotidase) (5'-NT) (EC 3.1.3.5) (Acid phosphatase 3) (Ecto-5'-nucleotidase) (Protein tyrosine phosphatase ACP3) (EC 3.1.3.48) (Thiamine monophosphatase) (TMPase) [Cleaved into: PAPf39] ACP3 ACPP Homo sapiens (Human) adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; lipid metabolic process [GO:0006629]; lysosome organization [GO:0007040]; nucleotide metabolic process [GO:0009117]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; purine nucleobase metabolic process [GO:0006144]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772] acid phosphatase complex [GO:1904097]; azurophil granule membrane [GO:0035577]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; nucleus [GO:0005634]; phosphatidylinositol phosphate phosphatase complex [GO:1904144]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506] 5'-nucleotidase activity [GO:0008253]; acid phosphatase activity [GO:0003993]; identical protein binding [GO:0042802]; lysophosphatidic acid phosphatase activity [GO:0052642]; molecular adaptor activity [GO:0060090]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; protein tyrosine phosphatase activity [GO:0004725]; thiamine phosphate phosphatase activity [GO:0042131]; XMP 5'-nucleosidase activity [GO:0106411] 0.9637 -2.1116 ELKFVTLVFR 0 9.13522 9.96607 9.69371 9.69638 9.61338 0 9.44905 9.52329 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.758 0 10.7315 P15311 EZRI_HUMAN Ezrin (Cytovillin) (Villin-2) (p81) EZR VIL2 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; astral microtubule organization [GO:0030953]; cellular response to cAMP [GO:0071320]; cortical microtubule organization [GO:0043622]; establishment of centrosome localization [GO:0051660]; establishment of endothelial barrier [GO:0061028]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; filopodium assembly [GO:0046847]; intestinal D-glucose absorption [GO:0001951]; leukocyte cell-cell adhesion [GO:0007159]; membrane to membrane docking [GO:0022614]; microvillus assembly [GO:0030033]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; postsynaptic actin cytoskeleton organization [GO:0098974]; protein kinase A signaling [GO:0010737]; protein localization to cell cortex [GO:0072697]; protein localization to plasma membrane [GO:0072659]; protein-containing complex localization [GO:0031503]; receptor internalization [GO:0031623]; regulation of cell shape [GO:0008360]; regulation of microvillus length [GO:0032532]; regulation of organelle assembly [GO:1902115]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; terminal web assembly [GO:1902896] actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; adherens junction [GO:0005912]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border [GO:0005903]; cell periphery [GO:0071944]; cell projection [GO:0042995]; ciliary basal body [GO:0036064]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoplasmic side of apical plasma membrane [GO:0098592]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extrinsic component of membrane [GO:0019898]; fibrillar center [GO:0001650]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; membrane [GO:0016020]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; uropod [GO:0001931]; vesicle [GO:0031982] actin binding [GO:0003779]; actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protein domain specific binding [GO:0019904]; protein kinase A binding [GO:0051018]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase A regulatory subunit binding [GO:0034237]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548] 0 7.9739 ALQLEEER 11.6941 10.3603 11.4081 0 0 0 11.5987 11.8709 11.7136 0 9.41399 0 0 0 9.58538 0 0 10.552 0 8.74406 0 9.84183 0 0 0 0 0 P15391 CD19_HUMAN B-lymphocyte antigen CD19 (B-lymphocyte surface antigen B4) (Differentiation antigen CD19) (T-cell surface antigen Leu-12) (CD antigen CD19) CD19 Homo sapiens (Human) antigen receptor-mediated signaling pathway [GO:0050851]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; B-1 B cell differentiation [GO:0001923]; immunoglobulin mediated immune response [GO:0016064]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; regulation of B cell activation [GO:0050864]; regulation of B cell receptor signaling pathway [GO:0050855] external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] 0.84871 0.16429 ATAQDAGK 0 0 0 0 0 0 10.3295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P15498 VAV_HUMAN Proto-oncogene vav VAV1 VAV Homo sapiens (Human) cell migration [GO:0016477]; cellular response to xenobiotic stimulus [GO:0071466]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; neutrophil chemotaxis [GO:0030593]; platelet activation [GO:0030168]; positive regulation of GTPase activity [GO:0043547]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; reactive oxygen species metabolic process [GO:0072593]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886] guanyl-nucleotide exchange factor activity [GO:0005085]; metal ion binding [GO:0046872]; phosphorylation-dependent protein binding [GO:0140031]; phosphotyrosine residue binding [GO:0001784] 0.96224 -2.4867 DLAQCVNEVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.85265 0 10.2692 0 0 0 0 9.44232 0 0 0 0 0 P15509 CSF2R_HUMAN Granulocyte-macrophage colony-stimulating factor receptor subunit alpha (GM-CSF-R-alpha) (GMCSFR-alpha) (GMR-alpha) (CDw116) (CD antigen CD116) CSF2RA CSF2R CSF2RY Homo sapiens (Human) cytokine-mediated signaling pathway [GO:0019221]; granulocyte-macrophage colony-stimulating factor signaling pathway [GO:0038157]; positive regulation of leukocyte proliferation [GO:0070665]; protein phosphorylation [GO:0006468]; receptor signaling pathway via JAK-STAT [GO:0007259] external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; granulocyte macrophage colony-stimulating factor receptor complex [GO:0030526]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; signaling receptor activity [GO:0038023] 0.91334 -0.75809 DVQYFLYIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.60642 0 0 0 0 P15514 AREG_HUMAN Amphiregulin (AR) (Colorectum cell-derived growth factor) (CRDGF) AREG AREGB SDGF Homo sapiens (Human) cell-cell signaling [GO:0007267]; dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis [GO:0060598]; epidermal growth factor receptor signaling pathway [GO:0007173]; epithelial cell proliferation involved in mammary gland duct elongation [GO:0060750]; ERBB2-EGFR signaling pathway [GO:0038134]; G protein-coupled receptor signaling pathway [GO:0007186]; glial cell proliferation [GO:0014009]; mammary gland alveolus development [GO:0060749]; mammary gland branching involved in thelarche [GO:0060744]; negative regulation of osteoblast differentiation [GO:0045668]; neuron projection development [GO:0031175]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of keratinocyte proliferation [GO:0010838]; response to cAMP [GO:0051591]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to hydrogen peroxide [GO:0042542]; response to peptide hormone [GO:0043434] cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634] cytokine activity [GO:0005125]; epidermal growth factor receptor binding [GO:0005154]; growth factor activity [GO:0008083]; receptor ligand activity [GO:0048018]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297] 0.81797 0.22072 QENGNVHAIA 0 0 0 0 0 0 0 0 0 9.8744 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P15538 C11B1_HUMAN "Cytochrome P450 11B1, mitochondrial (CYPXIB1) (Cytochrome P-450c11) (Cytochrome P450C11) (Steroid 11-beta-hydroxylase, CYP11B1) (EC 1.14.15.4)" CYP11B1 S11BH Homo sapiens (Human) aldosterone biosynthetic process [GO:0032342]; C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to hormone stimulus [GO:0032870]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to potassium ion [GO:0035865]; cholesterol metabolic process [GO:0008203]; cortisol biosynthetic process [GO:0034651]; cortisol metabolic process [GO:0034650]; glucocorticoid biosynthetic process [GO:0006704]; glucose homeostasis [GO:0042593]; immune response [GO:0006955]; regulation of blood pressure [GO:0008217]; sterol metabolic process [GO:0016125] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] corticosterone 18-monooxygenase activity [GO:0047783]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; steroid 11-beta-monooxygenase activity [GO:0004507] 0.93328 -1.2796 SLSRWTSPK 0 0 0 0 0 0 0 0 0 0 0 0 9.85083 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P15559 NQO1_HUMAN NAD(P)H dehydrogenase [quinone] 1 (EC 1.6.5.2) (Azoreductase) (DT-diaphorase) (DTD) (Menadione reductase) (NAD(P)H:quinone oxidoreductase 1) (Phylloquinone reductase) (Quinone reductase 1) (QR1) NQO1 DIA4 NMOR1 Homo sapiens (Human) "aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; cellular response to oxidative stress [GO:0034599]; innate immune response [GO:0045087]; NADH oxidation [GO:0006116]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; negative regulation of protein catabolic process [GO:0042177]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; protein catabolic process [GO:0030163]; protein polyubiquitination [GO:0000209]; removal of superoxide radicals [GO:0019430]; response to alkaloid [GO:0043279]; response to amine [GO:0014075]; response to carbohydrate [GO:0009743]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to flavonoid [GO:1905395]; response to hormone [GO:0009725]; response to hydrogen sulfide [GO:1904880]; response to ischemia [GO:0002931]; response to L-glutamine [GO:1904844]; response to lipopolysaccharide [GO:0032496]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to testosterone [GO:0033574]; response to tetrachloromethane [GO:1904772]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; ubiquinone metabolic process [GO:0006743]; vitamin E metabolic process [GO:0042360]; vitamin K metabolic process [GO:0042373]; xenobiotic metabolic process [GO:0006805]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; synapse [GO:0045202] "cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; NADH dehydrogenase (quinone) activity [GO:0050136]; NADPH dehydrogenase (quinone) activity [GO:0008753]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]" 0.22899 0.87344 IQILEGWK 0 10.3751 10.2675 0 0 0 10.5506 10.4165 10.5583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P15586 GNS_HUMAN N-acetylglucosamine-6-sulfatase (EC 3.1.6.14) (Glucosamine-6-sulfatase) (G6S) GNS Homo sapiens (Human) glycosaminoglycan catabolic process [GO:0006027]; keratan sulfate catabolic process [GO:0042340] azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202] glycosaminoglycan binding [GO:0005539]; metal ion binding [GO:0046872]; N-acetylglucosamine-6-sulfatase activity [GO:0008449]; sulfate binding [GO:0043199]; sulfuric ester hydrolase activity [GO:0008484] 0.51646 0.59321 AFQNVFAPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0546 0 0 11.0081 0 0 0 0 0 P15621 ZNF44_HUMAN Zinc finger protein 44 (Gonadotropin-inducible ovary transcription repressor 2) (GIOT-2) (Zinc finger protein 55) (Zinc finger protein 58) (Zinc finger protein KOX7) ZNF44 GIOT2 KOX7 ZNF55 ZNF58 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.96287 -2.5302 AFDSPSVFQR 10.6872 0 0 9.61842 12.8472 9.57824 10.3572 10.5108 10.5417 0 11.0336 0 8.73373 0 0 0 0 0 0 0 0 9.74317 0 0 0 9.67419 10.152 P15735 PHKG2_HUMAN "Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) (EC 2.7.11.19) (PSK-C3) (Phosphorylase kinase subunit gamma-2)" PHKG2 Homo sapiens (Human) generation of precursor metabolites and energy [GO:0006091]; glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980]; glycogen metabolic process [GO:0005977]; positive regulation of glycogen catabolic process [GO:0045819]; protein phosphorylation [GO:0006468] cytosol [GO:0005829]; phosphorylase kinase complex [GO:0005964] ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; phosphorylase kinase activity [GO:0004689]; protein serine/threonine kinase activity [GO:0004674]; tau-protein kinase activity [GO:0050321] 0.96927 -3.404 GVSSVVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.84 0 0 P15822 ZEP1_HUMAN Zinc finger protein 40 (Cirhin interaction protein) (CIRIP) (Gate keeper of apoptosis-activating protein) (GAAP) (Human immunodeficiency virus type I enhancer-binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1) HIVEP1 ZNF40 Homo sapiens (Human) BMP signaling pathway [GO:0030509]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96896 -6.6637 ACETQPKQTSVASANQVSR 0 0 0 0 0 0 0 0 10.2099 11.1481 0 0 0 0 11.1296 0 0 0 10.1387 9.53493 0 0 0 0 10.9449 0 0 P15880 RS2_HUMAN Small ribosomal subunit protein uS5 (40S ribosomal protein S2) (40S ribosomal protein S4) (Protein LLRep3) RPS2 RPS4 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; fibroblast growth factor binding [GO:0017134]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0 7.4406 ATFDAISK 0 0 0 0 0 0 9.67343 9.58192 0 0 9.31728 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2636 8.99704 9.74411 P15884 ITF2_HUMAN Transcription factor 4 (TCF-4) (Class B basic helix-loop-helix protein 19) (bHLHb19) (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2) TCF4 BHLHB19 ITF2 SEF2 Homo sapiens (Human) cell differentiation [GO:0030154]; nervous system development [GO:0007399]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein-DNA complex assembly [GO:0065004]; regulation of transcription by RNA polymerase II [GO:0006357] beta-catenin-TCF complex [GO:1990907]; beta-catenin-TCF7L2 complex [GO:0070369]; chromatin [GO:0000785]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "beta-catenin binding [GO:0008013]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; E-box binding [GO:0070888]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]; TFIIB-class transcription factor binding [GO:0001093]" 0.94033 -1.3272 DIKSITSNNDDEDLTPEQKAER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.5418 0 0 0 0 10.1701 0 0 0 10.9112 10.9571 0 P15907 SIAT1_HUMAN "Beta-galactoside alpha-2,6-sialyltransferase 1 (Alpha 2,6-ST 1) (EC 2.4.3.1) (B-cell antigen CD75) (CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1) (ST6Gal I) (ST6GalI) (Sialyltransferase 1)" ST6GAL1 SIAT1 Homo sapiens (Human) humoral immune response [GO:0006959]; N-acetylneuraminate metabolic process [GO:0006054]; negative regulation of chemotaxis [GO:0050922]; negative regulation of macrophage apoptotic process [GO:2000110]; O-glycan processing [GO:0016266]; positive regulation of mononuclear cell proliferation [GO:0032946]; protein N-linked glycosylation via asparagine [GO:0018279]; protein sialylation [GO:1990743]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; response to ethanol [GO:0045471]; sialylation [GO:0097503]; viral protein processing [GO:0019082] endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi medial cisterna [GO:0005797]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138] "beta-galactoside alpha-2,6-sialyltransferase activity [GO:0003835]; protein homodimerization activity [GO:0042803]; sialyltransferase activity [GO:0008373]" 0.64436 0.39623 GPGPGIK 0 0 0 0 9.95172 9.83905 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P15918 RAG1_HUMAN V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74) [Includes: Endonuclease RAG1 (EC 3.1.-.-); E3 ubiquitin-protein ligase RAG1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RAG1)] RAG1 RNF74 Homo sapiens (Human) adaptive immune response [GO:0002250]; B cell differentiation [GO:0030183]; chromatin organization [GO:0006325]; DNA recombination [GO:0006310]; histone monoubiquitination [GO:0010390]; immune response [GO:0006955]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of thymocyte apoptotic process [GO:0070244]; positive regulation of T cell differentiation [GO:0045582]; pre-B cell allelic exclusion [GO:0002331]; protein autoubiquitination [GO:0051865]; regulation of behavioral fear response [GO:2000822]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; V(D)J recombination [GO:0033151]; visual learning [GO:0008542] DNA recombinase complex [GO:0097519]; endodeoxyribonuclease complex [GO:1905347]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; histone binding [GO:0042393]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; sequence-specific DNA binding [GO:0043565]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.96418 -2.4239 AQARISSKDVMK 14.2761 0 0 0 0 0 0 0 0 9.42629 0 15.3893 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P15923 TFE2_HUMAN Transcription factor E2-alpha (Class B basic helix-loop-helix protein 21) (bHLHb21) (Immunoglobulin enhancer-binding factor E12/E47) (Immunoglobulin transcription factor 1) (Kappa-E2-binding factor) (Transcription factor 3) (TCF-3) (Transcription factor ITF-1) TCF3 BHLHB21 E2A ITF1 Homo sapiens (Human) B cell differentiation [GO:0030183]; B cell lineage commitment [GO:0002326]; immunoglobulin V(D)J recombination [GO:0033152]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell cycle [GO:0045787]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; cytoplasm [GO:0005737]; euchromatin [GO:0000791]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; RNA polymerase II transcription regulator complex [GO:0090575]; transcription regulator complex [GO:0005667] "bHLH transcription factor binding [GO:0043425]; cis-regulatory region sequence-specific DNA binding [GO:0000987]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription factor binding [GO:0140297]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; E-box binding [GO:0070888]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; vitamin D response element binding [GO:0070644]" 0.92728 -1.1892 EDEENTSAADHSEEEK 0 0 9.30017 0 0 0 0 0 0 0 10.3689 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P15924 DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) DSP Homo sapiens (Human) adherens junction organization [GO:0034332]; bundle of His cell-Purkinje myocyte adhesion involved in cell communication [GO:0086073]; cell-cell adhesion [GO:0098609]; desmosome organization [GO:0002934]; epidermis development [GO:0008544]; epithelial cell-cell adhesion [GO:0090136]; intermediate filament cytoskeleton organization [GO:0045104]; intermediate filament organization [GO:0045109]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein localization to cell-cell junction [GO:0150105]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; skin development [GO:0043588]; ventricular compact myocardium morphogenesis [GO:0003223]; wound healing [GO:0042060] adherens junction [GO:0005912]; basolateral plasma membrane [GO:0016323]; cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; desmosome [GO:0030057]; extracellular exosome [GO:0070062]; fascia adherens [GO:0005916]; ficolin-1-rich granule membrane [GO:0101003]; intercalated disc [GO:0014704]; intermediate filament [GO:0005882]; nucleus [GO:0005634]; plasma membrane [GO:0005886] cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication [GO:0086083]; protein kinase C binding [GO:0005080]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; structural constituent of cytoskeleton [GO:0005200]; structural molecule activity [GO:0005198] 0.0079787 2.0606 AEFQEEAK 0 11.0278 0 0 0 0 0 0 0 12.432 9.46121 0 0 0 11.7959 0 9.40111 11.0124 10.008 13.4235 0 8.62004 0 0 13.7462 10.5198 0 P15976 GATA1_HUMAN Erythroid transcription factor (Eryf1) (GATA-binding factor 1) (GATA-1) (GF-1) (NF-E1 DNA-binding protein) GATA1 ERYF1 GF1 Homo sapiens (Human) animal organ regeneration [GO:0031100]; basophil differentiation [GO:0030221]; bone mineralization [GO:0030282]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to cAMP [GO:0071320]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to thyroid hormone stimulus [GO:0097067]; dendritic cell differentiation [GO:0097028]; eosinophil differentiation [GO:0030222]; eosinophil fate commitment [GO:0035854]; erythrocyte development [GO:0048821]; erythrocyte differentiation [GO:0030218]; homeostasis of number of cells within a tissue [GO:0048873]; in utero embryonic development [GO:0001701]; male gonad development [GO:0008584]; megakaryocyte differentiation [GO:0030219]; myeloid cell apoptotic process [GO:0033028]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone mineralization [GO:0030502]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of myeloid cell apoptotic process [GO:0033033]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; osteoblast proliferation [GO:0033687]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; primitive erythrocyte differentiation [GO:0060319]; regulation of definitive erythrocyte differentiation [GO:0010724]; regulation of glycoprotein biosynthetic process [GO:0010559]; regulation of primitive erythrocyte differentiation [GO:0010725]; Sertoli cell development [GO:0060009]; transcription by RNA polymerase II [GO:0006366] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; transcription regulator complex [GO:0005667]; transcription repressor complex [GO:0017053] "C2H2 zinc finger domain binding [GO:0070742]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; p53 binding [GO:0002039]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]; transcription coactivator binding [GO:0001223]; transcription coregulator binding [GO:0001221]; zinc ion binding [GO:0008270]" 0.84153 0.18107 EDSPPQAVEDLDGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.17794 9.29361 0 0 0 0 0 0 0 0 0 P16035 TIMP2_HUMAN Metalloproteinase inhibitor 2 (CSC-21K) (Tissue inhibitor of metalloproteinases 2) (TIMP-2) TIMP2 Homo sapiens (Human) negative regulation of endopeptidase activity [GO:0010951]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of metallopeptidase activity [GO:1905049]; response to cytokine [GO:0034097]; response to hormone [GO:0009725] collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724] metalloendopeptidase inhibitor activity [GO:0008191]; molecular function inhibitor activity [GO:0140678]; peptidase inhibitor activity [GO:0030414]; protease binding [GO:0002020]; zinc ion binding [GO:0008270] 0.95455 -1.502 NINGHQAKFFACIK 10.0647 10.1022 10.0001 0 0 0 10.4414 10.4986 10.6136 10.1237 10.3718 10.2286 9.09389 0 9.10483 8.85247 0 0 0 0 0 0 0 0 8.82864 0 0 P16066 ANPRA_HUMAN Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A) NPR1 ANPRA Homo sapiens (Human) blood vessel diameter maintenance [GO:0097746]; body fluid secretion [GO:0007589]; cell surface receptor signaling pathway [GO:0007166]; cGMP biosynthetic process [GO:0006182]; cGMP-mediated signaling [GO:0019934]; dopamine metabolic process [GO:0042417]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell growth [GO:0030308]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP-mediated signaling [GO:0010753]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of urine volume [GO:0035810]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of blood pressure [GO:0008217]; regulation of vascular permeability [GO:0043114] ANPR-A receptor complex [GO:1990620]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] ATP binding [GO:0005524]; G protein-coupled peptide receptor activity [GO:0008528]; GTP binding [GO:0005525]; guanylate cyclase activity [GO:0004383]; hormone binding [GO:0042562]; natriuretic peptide receptor activity [GO:0016941]; peptide hormone binding [GO:0017046]; peptide receptor activity [GO:0001653]; protein kinase activity [GO:0004672] 0.96739 -2.8599 LHACEVAR 0 0 11.6879 0 0 0 0 10.9076 0 0 7.74187 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P16150 LEUK_HUMAN Leukosialin (GPL115) (Galactoglycoprotein) (GALGP) (Leukocyte sialoglycoprotein) (Sialophorin) (CD antigen CD43) [Cleaved into: CD43 cytoplasmic tail (CD43-ct) (CD43ct)] SPN CD43 Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; cellular defense response [GO:0006968]; chemotaxis [GO:0006935]; defense response to bacterium [GO:0042742]; establishment or maintenance of cell polarity [GO:0007163]; immune response [GO:0006955]; leukocyte tethering or rolling [GO:0050901]; negative regulation of cell adhesion [GO:0007162]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of T cell migration [GO:2000406]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of immune response [GO:0050776]; regulation of T cell migration [GO:2000404]; signal transduction [GO:0007165]; T-helper 1 cell lineage commitment [GO:0002296] cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; PML body [GO:0016605]; uropod [GO:0001931] heat shock protein binding [GO:0031072]; Hsp70 protein binding [GO:0030544]; transmembrane signaling receptor activity [GO:0004888] 0.79991 0.23979 MYTTSITSDPK 0 0 0 0 0 0 0 0 0 0 9.82396 9.89104 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P16152 CBR1_HUMAN "Carbonyl reductase [NADPH] 1 (EC 1.1.1.184) (15-hydroxyprostaglandin dehydrogenase [NADP(+)]) (EC 1.1.1.196, EC 1.1.1.197) (20-beta-hydroxysteroid dehydrogenase) (Alcohol dehydrogenase [NAD(P)+] CBR1) (EC 1.1.1.71) (NADPH-dependent carbonyl reductase 1) (Prostaglandin 9-ketoreductase) (PG-9-KR) (Prostaglandin-E(2) 9-reductase) (EC 1.1.1.189) (Short chain dehydrogenase/reductase family 21C member 1)" CBR1 CBR CRN SDR21C1 Homo sapiens (Human) cyclooxygenase pathway [GO:0019371]; epithelial cell differentiation [GO:0030855]; glucocorticoid metabolic process [GO:0008211]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; vitamin K metabolic process [GO:0042373]; xenobiotic metabolic process [GO:0006805] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular vesicle [GO:1903561] "15-hydroxyprostaglandin dehydrogenase (NADP+) activity [GO:0047021]; 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity [GO:0047020]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; carbonyl reductase (NADPH) activity [GO:0004090]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; prostaglandin-E2 9-reductase activity [GO:0050221]" 0 3.1413 EGWPSSAYGVTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0244 10.2041 0 0 9.11194 8.81295 9.00492 10.4733 0 0 12.2048 11.8812 11.4854 P16157 ANK1_HUMAN Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) ANK1 ANK Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] basolateral plasma membrane [GO:0016323]; cytoplasmic side of plasma membrane [GO:0009898]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; M band [GO:0031430]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; sarcoplasmic reticulum [GO:0016529]; spectrin-associated cytoskeleton [GO:0014731] ATPase binding [GO:0051117]; cytoskeletal anchor activity [GO:0008093]; enzyme binding [GO:0019899]; protein phosphatase binding [GO:0019903]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]; structural molecule activity [GO:0005198]; transmembrane transporter binding [GO:0044325] 0.95195 -1.3902 DVDEEKELLDFVPK 0 0 11.5195 0 0 0 0 0 0 0 0 0 10.1107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P16219 ACADS_HUMAN "Short-chain specific acyl-CoA dehydrogenase, mitochondrial (SCAD) (EC 1.3.8.1) (Butyryl-CoA dehydrogenase)" ACADS Homo sapiens (Human) butyrate catabolic process [GO:0046359]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539] centrosome [GO:0005813]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] acyl-CoA dehydrogenase activity [GO:0003995]; butyryl-CoA dehydrogenase activity [GO:0004085]; flavin adenine dinucleotide binding [GO:0050660]; short-branched-chain-acyl-CoA dehydrogenase activity [GO:0016937] 0.92401 -1.0094 GSSTANLIFEDCRIPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.98465 P16234 PGFRA_HUMAN Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a) PDGFRA PDGFR2 RHEPDGFRA Homo sapiens (Human) adrenal gland development [GO:0030325]; cardiac myofibril assembly [GO:0055003]; cell activation [GO:0001775]; cell chemotaxis [GO:0060326]; cellular response to amino acid stimulus [GO:0071230]; cellular response to reactive oxygen species [GO:0034614]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic skeletal system morphogenesis [GO:0048704]; estrogen metabolic process [GO:0008210]; extracellular matrix organization [GO:0030198]; face morphogenesis [GO:0060325]; hematopoietic progenitor cell differentiation [GO:0002244]; in utero embryonic development [GO:0001701]; Leydig cell differentiation [GO:0033327]; lung development [GO:0030324]; luteinization [GO:0001553]; male genitalia development [GO:0030539]; metanephric glomerular capillary formation [GO:0072277]; negative regulation of platelet activation [GO:0010544]; odontogenesis of dentin-containing tooth [GO:0042475]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol-mediated signaling [GO:0048015]; platelet aggregation [GO:0070527]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; platelet-derived growth factor receptor-alpha signaling pathway [GO:0035790]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; protein autophosphorylation [GO:0046777]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of chemotaxis [GO:0050920]; regulation of mesenchymal stem cell differentiation [GO:2000739]; retina vasculature development in camera-type eye [GO:0061298]; roof of mouth development [GO:0060021]; signal transduction involved in regulation of gene expression [GO:0023019]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; white fat cell differentiation [GO:0050872]; wound healing [GO:0042060] cell junction [GO:0030054]; cilium [GO:0005929]; cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; microvillus [GO:0005902]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235] ATP binding [GO:0005524]; BBSome binding [GO:0062063]; platelet-derived growth factor alpha-receptor activity [GO:0005018]; platelet-derived growth factor binding [GO:0048407]; platelet-derived growth factor receptor binding [GO:0005161]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor receptor activity [GO:0005021] 0.95527 -1.5855 GKKFQTIPFNVYALK 0 0 0 0 8.94254 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P16260 GDC_HUMAN Solute carrier family 25 member 16 (Graves disease autoantigen) (GDA) (Graves disease carrier protein) (GDC) (Graves' didease protein) (hGP) (Mitochondrial solute carrier protein homolog) SLC25A16 GDA Homo sapiens (Human) coenzyme A biosynthetic process [GO:0015937]; mitochondrial coenzyme A transmembrane transport [GO:1990559]; mitochondrial transport [GO:0006839] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] antiporter activity [GO:0015297]; coenzyme A transmembrane transporter activity [GO:0015228]; secondary active transmembrane transporter activity [GO:0015291] 0.9267 -1.2075 LGISGHVHR 0 0 0 0 0 0 0 0 0 0 8.739 0 0 0 0 0 0 12.2857 0 0 0 0 9.58984 0 0 0 0 P16278 BGAL_HUMAN Beta-galactosidase (EC 3.2.1.23) (Acid beta-galactosidase) (Lactase) (Elastin receptor 1) GLB1 ELNR1 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; galactose catabolic process [GO:0019388]; glycosphingolipid metabolic process [GO:0006687]; heparan sulfate proteoglycan catabolic process [GO:0030200]; keratan sulfate catabolic process [GO:0042340]; response to cortisone [GO:0051413]; response to Thyroglobulin triiodothyronine [GO:1904016] azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; perinuclear region of cytoplasm [GO:0048471]; vacuole [GO:0005773] beta-galactosidase activity [GO:0004565]; galactoside binding [GO:0016936]; protein homodimerization activity [GO:0042803] 0.9678 -2.855 GLRNATQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.04327 0 0 0 0 0 0 P16284 PECA1_HUMAN Platelet endothelial cell adhesion molecule (PECAM-1) (EndoCAM) (GPIIA') (PECA1) (CD antigen CD31) PECAM1 Homo sapiens (Human) bicellular tight junction assembly [GO:0070830]; cell recognition [GO:0008037]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; diapedesis [GO:0050904]; establishment of endothelial barrier [GO:0061028]; glomerular endothelium development [GO:0072011]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; leukocyte cell-cell adhesion [GO:0007159]; maintenance of blood-brain barrier [GO:0035633]; monocyte extravasation [GO:0035696]; neutrophil extravasation [GO:0072672]; phagocytosis [GO:0006909]; positive regulation of cell migration [GO:0030335]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to cell-cell junction [GO:0150107]; positive regulation of protein phosphorylation [GO:0001934]; signal transduction [GO:0007165] cell-cell junction [GO:0005911]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; protein-containing complex [GO:0032991]; secretory granule membrane [GO:0030667] protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888] 0.96941 -3.1488 DQNFVILEFPVEEQDR 0 0 0 11.3739 0 0 0 0 13.5021 0 0 0 10.4949 10.936 0 0 0 0 0 0 0 0 0 0 0 0 8.67129 P16298 PP2BB_HUMAN Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calmodulin-dependent calcineurin A subunit beta isoform) (CNA beta) PPP3CB CALNA2 CALNB CNA2 Homo sapiens (Human) axon extension [GO:0048675]; calcineurin-mediated signaling [GO:0097720]; calcineurin-NFAT signaling cascade [GO:0033173]; calcium-ion regulated exocytosis [GO:0017156]; dephosphorylation [GO:0016311]; heart development [GO:0007507]; learning [GO:0007612]; locomotion involved in locomotory behavior [GO:0031987]; lymphangiogenesis [GO:0001946]; memory [GO:0007613]; negative regulation of calcium ion import across plasma membrane [GO:1905949]; negative regulation of signaling [GO:0023057]; negative regulation of T cell mediated cytotoxicity [GO:0001915]; negative regulation of voltage-gated calcium channel activity [GO:1901386]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of calcium ion import across plasma membrane [GO:1905665]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lysosome organization [GO:1905673]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; protein dephosphorylation [GO:0006470]; protein phosphorylation [GO:0006468]; regulation of insulin secretion [GO:0050796]; regulation of synaptic plasticity [GO:0048167]; regulation of synaptic vesicle endocytosis [GO:1900242]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; skeletal muscle fiber development [GO:0048741]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell homeostasis [GO:0043029]; T cell mediated cytotoxicity [GO:0001913]; T cell proliferation [GO:0042098] calcineurin complex [GO:0005955]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein serine/threonine phosphatase complex [GO:0008287]; T-tubule [GO:0030315]; Z disc [GO:0030018] calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; calmodulin-dependent protein phosphatase activity [GO:0033192]; enzyme binding [GO:0019899]; myosin phosphatase activity [GO:0017018]; protein dimerization activity [GO:0046983]; protein phosphatase 2B binding [GO:0030346]; protein serine/threonine phosphatase activity [GO:0004722] 0.78649 0.25848 LTSEEVFDLDGIPR 0 0 0 0 0 0 9.21301 0 0 0 0 0 0 0 0 0 0 0 0 10.787 0 10.5142 0 10.5964 0 0 0 P16383 GCFC2_HUMAN Intron Large complex component GCFC2 (GC-rich sequence DNA-binding factor) (GC-rich sequence DNA-binding factor 2) (Transcription factor 9) (TCF-9) GCFC2 C2orf3 GCF TCF9 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; negative regulation of DNA-templated transcription [GO:0045892]; regulation of DNA-templated transcription [GO:0006355]; spliceosomal complex assembly [GO:0000245]" cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type post-mRNA release spliceosomal complex [GO:0071008] DNA binding [GO:0003677] 0.91814 -0.85613 DDQGLSSDSSSSLGEK 0 0 0 8.71177 8.94219 0 0 0 0 11.5935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P16389 KCNA2_HUMAN Potassium voltage-gated channel subfamily A member 2 (NGK1) (Voltage-gated K(+) channel HuKIV) (Voltage-gated potassium channel HBK5) (Voltage-gated potassium channel subunit Kv1.2) KCNA2 Homo sapiens (Human) "cerebral cortex development [GO:0021987]; corpus callosum development [GO:0022038]; neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion export across plasma membrane [GO:0097623]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of monoatomic ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]" axon [GO:0030424]; axon initial segment [GO:0043194]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; voltage-gated potassium channel complex [GO:0008076] delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; potassium channel activity [GO:0005267]; voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential [GO:1905030]; voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential [GO:0099508]; voltage-gated potassium channel activity [GO:0005249] 0.84817 0.15587 FYELGEEAMEMFR 0 0 9.23981 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P16401 H15_HUMAN Histone H1.5 (Histone H1a) (Histone H1b) (Histone H1s-3) H1-5 H1F5 HIST1H1B Homo sapiens (Human) chromatin organization [GO:0006325]; chromosome condensation [GO:0030261]; establishment of protein localization to chromatin [GO:0071169]; muscle organ development [GO:0007517]; negative regulation of DNA recombination [GO:0045910]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleosome assembly [GO:0006334]; protein stabilization [GO:0050821] chromatin [GO:0000785]; chromosome [GO:0005694]; heterochromatin [GO:0000792]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634] chromatin DNA binding [GO:0031490]; double-stranded DNA binding [GO:0003690]; histone deacetylase binding [GO:0042826]; nucleosomal DNA binding [GO:0031492]; RNA binding [GO:0003723]; structural constituent of chromatin [GO:0030527] 0 39.169 AAGAGAAK 11.5132 11.4883 11.4537 0 0 0 11.3865 11.3082 11.8011 11.7593 10.3937 12.6464 10.7017 9.80218 9.32278 11.8849 11.6832 11.3831 9.44748 10.396 11.0116 9.42905 10.6435 10.5271 11.755 10.076 10.5422 P16402 H13_HUMAN Histone H1.3 (Histone H1c) (Histone H1s-2) H1-3 H1F3 HIST1H1D Homo sapiens (Human) chromosome condensation [GO:0030261]; negative regulation of DNA recombination [GO:0045910]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleosome assembly [GO:0006334] chromatin [GO:0000785]; euchromatin [GO:0000791]; nucleosome [GO:0000786]; nucleus [GO:0005634] chromatin DNA binding [GO:0031490]; double-stranded DNA binding [GO:0003690]; nucleosomal DNA binding [GO:0031492]; RNA binding [GO:0003723]; structural constituent of chromatin [GO:0030527] 0 13.803 AASGEGKPKAK 11.7474 11.8234 11.5014 10.7889 13.389 9.39834 12.9053 12.7305 12.7299 11.2477 17.5305 12.1592 15.0931 11.5791 9.97025 15.2166 15.0813 12.0549 14.7291 11.8542 14.3982 14.2519 11.9688 13.8054 12.3383 12.253 13.4196 P16403 H12_HUMAN Histone H1.2 (Histone H1c) (Histone H1d) (Histone H1s-1) H1-2 H1F2 HIST1H1C Homo sapiens (Human) chromosome condensation [GO:0030261]; histone H3-K27 trimethylation [GO:0098532]; histone H3-K4 trimethylation [GO:0080182]; negative regulation of DNA recombination [GO:0045910]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleosome assembly [GO:0006334] euchromatin [GO:0000791]; nucleosome [GO:0000786]; nucleus [GO:0005634] chromatin DNA binding [GO:0031490]; double-stranded DNA binding [GO:0003690]; nucleosomal DNA binding [GO:0031492]; RNA binding [GO:0003723]; structural constituent of chromatin [GO:0030527] 0 33.445 ALAAAGYDVEK 10.7203 10.8471 10.7921 0 0 9.20369 11.6035 11.5508 11.5494 9.52276 0 0 8.68057 8.60733 8.55513 0 8.92508 8.968 10.8832 10.8504 10.8415 11.0088 11.021 11.0662 9.99986 9.89351 10.0168 P16415 ZN823_HUMAN Zinc finger protein 823 (Zinc finger protein ZFP-36) ZNF823 ZFP36 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.88267 -0.27226 AFPFYSSYLR 0 0 0 0 0 0 8.45311 8.54183 8.36076 0 0 0 0 0 0 0 0 9.44226 0 0 0 0 0 0 0 0 0 P16422 EPCAM_HUMAN Epithelial cell adhesion molecule (Ep-CAM) (Adenocarcinoma-associated antigen) (Cell surface glycoprotein Trop-1) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Epithelial glycoprotein 314) (EGP314) (hEGP314) (KS 1/4 antigen) (KSA) (Major gastrointestinal tumor-associated protein GA733-2) (Tumor-associated calcium signal transducer 1) (CD antigen CD326) EPCAM GA733-2 M1S2 M4S1 MIC18 TACSTD1 TROP1 Homo sapiens (Human) negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; signal transduction involved in regulation of gene expression [GO:0023019]; stem cell differentiation [GO:0048863]; ureteric bud development [GO:0001657] apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; lateral plasma membrane [GO:0016328]; plasma membrane [GO:0005886] cadherin binding involved in cell-cell adhesion [GO:0098641]; protein-containing complex binding [GO:0044877] 0.92047 -0.93284 AEMNGSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.02967 0 0 0 0 0 0 0 0 0 0 P16435 NCPR_HUMAN NADPH--cytochrome P450 reductase (CPR) (P450R) (EC 1.6.2.4) POR CYPOR Homo sapiens (Human) carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; electron transport chain [GO:0022900]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to dexamethasone [GO:0071548]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805] cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739] "cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]" 0.0059172 2.4327 DGALTQLNVAFSR 0 0 0 0 0 0 0 0 0 0 0 9.28311 9.7812 0 0 0 10.6407 10.9565 0 0 0 0 0 0 0 0 0 P16444 DPEP1_HUMAN Dipeptidase 1 (EC 3.4.13.19) (Beta-lactamase) (EC 3.5.2.6) (Dehydropeptidase-I) (Microsomal dipeptidase) (Renal dipeptidase) (hRDP) DPEP1 MDP RDP Homo sapiens (Human) antibiotic metabolic process [GO:0016999]; cellular response to calcium ion [GO:0071277]; cellular response to nitric oxide [GO:0071732]; cellular response to xenobiotic stimulus [GO:0071466]; glutathione catabolic process [GO:0006751]; glutathione metabolic process [GO:0006749]; homocysteine metabolic process [GO:0050667]; inflammatory response [GO:0006954]; lactam catabolic process [GO:0072340]; leukotriene D4 catabolic process [GO:1901749]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell migration [GO:0030336]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; neutrophil chemotaxis [GO:0030593]; proteolysis [GO:0006508] apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] beta-lactamase activity [GO:0008800]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; dipeptidase activity [GO:0016805]; GPI anchor binding [GO:0034235]; metallodipeptidase activity [GO:0070573]; metalloexopeptidase activity [GO:0008235]; modified amino acid binding [GO:0072341]; zinc ion binding [GO:0008270] 0.80369 0.24036 ALYQLGMR 0 10.2077 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P16452 EPB42_HUMAN Protein 4.2 (P4.2) (Erythrocyte membrane protein band 4.2) (Erythrocyte protein 4.2) EPB42 E42P Homo sapiens (Human) cell morphogenesis [GO:0000902]; erythrocyte maturation [GO:0043249]; hemoglobin metabolic process [GO:0020027]; multicellular organismal-level iron ion homeostasis [GO:0060586]; peptide cross-linking [GO:0018149]; regulation of cell shape [GO:0008360]; spleen development [GO:0048536] cortical cytoskeleton [GO:0030863]; cytoskeleton [GO:0005856]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; structural constituent of cytoskeleton [GO:0005200] 0.91819 -0.876 EVLERVEK 0 0 8.81932 0 0 0 0 0 0 9.41908 0 0 0 0 0 0 0 0 0 0 9.64357 0 0 0 0 0 0 P16455 MGMT_HUMAN Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) (6-O-methylguanine-DNA methyltransferase) (MGMT) (O-6-methylguanine-DNA-alkyltransferase) MGMT Homo sapiens (Human) cellular response to ionizing radiation [GO:0071479]; cellular response to organic cyclic compound [GO:0071407]; cellular response to oxidative stress [GO:0034599]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA ligation [GO:0006266]; DNA repair [GO:0006281]; mammary gland epithelial cell differentiation [GO:0060644]; negative regulation of apoptotic process [GO:0043066]; positive regulation of double-strand break repair [GO:2000781]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to toxic substance [GO:0009636]; response to xenobiotic stimulus [GO:0009410] membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-methyltransferase activity [GO:0009008]; methylated-DNA-[protein]-cysteine S-methyltransferase activity [GO:0003908]; methyltransferase activity [GO:0008168] 0.65769 0.39518 AVGGAMR 0 0 0 8.4045 0 0 0 0 0 0 0 0 0 0 0 0 9.33101 0 0 0 0 0 0 0 0 0 0 P16473 TSHR_HUMAN Thyrotropin receptor (Thyroid-stimulating hormone receptor) (TSH-R) TSHR LGR3 Homo sapiens (Human) "adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; cell-cell signaling [GO:0007267]; cellular response to glycoprotein [GO:1904588]; cellular response to thyrotropin-releasing hormone [GO:1905229]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; hormone-mediated signaling pathway [GO:0009755]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; thyroid-stimulating hormone signaling pathway [GO:0038194]" basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; thyroid-stimulating hormone receptor activity [GO:0004996] 0.959 -1.7633 AFQRDVFILLSKFGICK 0 9.94003 0 0 0 0 0 0 0 0 0 0 0 9.9612 0 0 0 0 0 0 0 0 0 0 0 0 0 P16499 PDE6A_HUMAN "Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha (GMP-PDE alpha) (EC 3.1.4.35) (PDE V-B1)" PDE6A PDEA Homo sapiens (Human) retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; visual perception [GO:0007601] photoreceptor disc membrane [GO:0097381]; photoreceptor outer segment membrane [GO:0042622]; plasma membrane [GO:0005886] "3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; metal ion binding [GO:0046872]" 0.96761 -2.7468 DIFQDIVK 0 0 0 0 0 0 0 0 0 8.83422 0 0 0 0 0 0 0 0 9.27279 9.52882 0 0 0 0 11.5301 0 12.1964 P16519 NEC2_HUMAN Neuroendocrine convertase 2 (NEC 2) (EC 3.4.21.94) (KEX2-like endoprotease 2) (Prohormone convertase 2) (Proprotein convertase 2) (PC2) PCSK2 NEC2 Homo sapiens (Human) enkephalin processing [GO:0034230]; insulin processing [GO:0030070]; islet amyloid polypeptide processing [GO:0034231]; nervous system development [GO:0007399]; peptide hormone processing [GO:0016486]; protein autoprocessing [GO:0016540]; protein processing [GO:0016485]; proteolysis [GO:0006508] dendrite [GO:0030425]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; perikaryon [GO:0043204]; secretory granule [GO:0030141]; trans-Golgi network [GO:0005802]; transport vesicle [GO:0030133] serine-type endopeptidase activity [GO:0004252] 0.50775 0.608 ARQVAAEHGFGVRK 0 9.98797 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.20011 0 P16591 FER_HUMAN Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) (Fujinami poultry sarcoma/Feline sarcoma-related protein Fer) (Proto-oncogene c-Fer) (Tyrosine kinase 3) (p94-Fer) FER TYK3 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; adherens junction assembly [GO:0034333]; adherens junction disassembly [GO:0120179]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; cellular response to insulin stimulus [GO:0032869]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to reactive oxygen species [GO:0034614]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; diapedesis [GO:0050904]; extracellular matrix-cell signaling [GO:0035426]; Fc-epsilon receptor signaling pathway [GO:0038095]; germ cell development [GO:0007281]; insulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028]; interleukin-6-mediated signaling pathway [GO:0070102]; intracellular signal transduction [GO:0035556]; Kit signaling pathway [GO:0038109]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of mast cell activation involved in immune response [GO:0033007]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of fibroblast migration [GO:0010762]; regulation of lamellipodium assembly [GO:0010591]; regulation of mast cell degranulation [GO:0043304]; regulation of protein phosphorylation [GO:0001932]; response to lipopolysaccharide [GO:0032496]; response to platelet-derived growth factor [GO:0036119]; Sertoli cell development [GO:0060009]; substrate adhesion-dependent cell spreading [GO:0034446]; tyrosine phosphorylation of STAT protein [GO:0007260] anchoring junction [GO:0070161]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nucleus [GO:0005634]; type III intermediate filament [GO:0045098] actin binding [GO:0003779]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; delta-catenin binding [GO:0070097]; epidermal growth factor receptor binding [GO:0005154]; gamma-catenin binding [GO:0045295]; lipid binding [GO:0008289]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein phosphatase 1 binding [GO:0008157]; protein tyrosine kinase activity [GO:0004713]; protein tyrosine kinase binding [GO:1990782]; small GTPase binding [GO:0031267] 0.95922 -1.8307 LTMMIKDK 0 10.0063 11.703 0 0 0 0 0 0 0 10.0756 0 0 0 0 0 0 0 9.57118 0 0 0 0 9.63836 0 0 10.3237 P16615 AT2A2_HUMAN "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) (SR Ca(2+)-ATPase 2) (EC 7.2.2.10) (Calcium pump 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase)" ATP2A2 ATP2B Homo sapiens (Human) autophagosome assembly [GO:0000045]; autophagosome membrane docking [GO:0016240]; calcium ion import into sarcoplasmic reticulum [GO:1990036]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport from cytosol to endoplasmic reticulum [GO:1903515]; cardiac muscle hypertrophy in response to stress [GO:0014898]; cell adhesion [GO:0007155]; cellular response to oxidative stress [GO:0034599]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; epidermis development [GO:0008544]; ER-nucleus signaling pathway [GO:0006984]; intracellular calcium ion homeostasis [GO:0006874]; mitochondrion-endoplasmic reticulum membrane tethering [GO:1990456]; monoatomic ion transmembrane transport [GO:0034220]; negative regulation of heart contraction [GO:0045822]; negative regulation of receptor binding [GO:1900121]; neuron cellular homeostasis [GO:0070050]; organelle localization by membrane tethering [GO:0140056]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of endoplasmic reticulum calcium ion concentration [GO:0032470]; positive regulation of heart rate [GO:0010460]; regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903233]; regulation of cardiac conduction [GO:1903779]; regulation of cardiac muscle cell action potential involved in regulation of contraction [GO:0098909]; regulation of cardiac muscle cell membrane potential [GO:0086036]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of the force of heart contraction [GO:0002026]; relaxation of cardiac muscle [GO:0055119]; response to endoplasmic reticulum stress [GO:0034976]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; transition between fast and slow fiber [GO:0014883] calcium ion-transporting ATPase complex [GO:0090534]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; longitudinal sarcoplasmic reticulum [GO:0014801]; membrane [GO:0016020]; plasma membrane [GO:0005886]; platelet dense tubular network membrane [GO:0031095]; ribbon synapse [GO:0097470]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; calcium ion binding [GO:0005509]; enzyme binding [GO:0019899]; P-type calcium transporter activity [GO:0005388]; P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential [GO:0086039]; S100 protein binding [GO:0044548]; transmembrane transporter binding [GO:0044325] 0.88446 -0.13629 DACLNARCFAR 0 10.3285 0 9.87851 10.7928 9.67627 10.7717 11.7788 11.2694 11.1283 10.6099 10.9545 10.9581 8.80365 0 0 0 9.67071 10.5773 0 10.2774 0 9.66123 0 12.4997 9.72134 12.0721 P16662 UD2B7_HUMAN "UDP-glucuronosyltransferase 2B7 (UDPGT 2B7) (UGT2B7) (EC 2.4.1.17) (3,4-catechol estrogen-specific UDPGT) (UDP-glucuronosyltransferase 2B9) (UDPGT 2B9) (UDPGTh-2)" UGT2B7 UGTB2B9 Homo sapiens (Human) androgen metabolic process [GO:0008209]; cellular glucuronidation [GO:0052695]; estrogen metabolic process [GO:0008210]; lipid metabolic process [GO:0006629]; xenobiotic metabolic process [GO:0006805] endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] glucuronosyltransferase activity [GO:0015020] 0.72768 0.34647 TILDELIQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.88686 0 0 0 0 0 0 0 0 0 0 0 0 P16671 CD36_HUMAN Platelet glycoprotein 4 (Fatty acid translocase) (FAT) (Glycoprotein IIIb) (GPIIIB) (Leukocyte differentiation antigen CD36) (PAS IV) (PAS-4) (Platelet collagen receptor) (Platelet glycoprotein IV) (GPIV) (Thrombospondin receptor) (CD antigen CD36) CD36 GP3B GP4 Homo sapiens (Human) "amyloid fibril formation [GO:1990000]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amyloid-beta [GO:1904646]; cellular response to diacyl bacterial lipopeptide [GO:0071726]; cellular response to hydroperoxide [GO:0071447]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to oxidised low-density lipoprotein particle stimulus [GO:0140052]; cGMP-mediated signaling [GO:0019934]; cholesterol import [GO:0070508]; cholesterol transport [GO:0030301]; defense response to Gram-positive bacterium [GO:0050830]; energy homeostasis [GO:0097009]; fatty acid metabolic process [GO:0006631]; intestinal absorption [GO:0050892]; intestinal cholesterol absorption [GO:0030299]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; lipid transport across blood-brain barrier [GO:1990379]; lipoprotein transport [GO:0042953]; long-chain fatty acid import across plasma membrane [GO:0015911]; long-chain fatty acid import into cell [GO:0044539]; long-chain fatty acid transport [GO:0015909]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle mediated signaling [GO:0055096]; MAPK cascade [GO:0000165]; negative regulation of gene expression [GO:0010629]; negative regulation of protein import into nucleus [GO:0042308]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nitric oxide mediated signal transduction [GO:0007263]; oxidised low-density lipoprotein particle clearance [GO:0150024]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; plasma lipoprotein particle clearance [GO:0034381]; positive regulation of blood coagulation [GO:0030194]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cholesterol storage [GO:0010886]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor production [GO:0032760]; production of molecular mediator involved in inflammatory response [GO:0002532]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of action potential [GO:0098900]; regulation of lipopolysaccharide-mediated signaling pathway [GO:0031664]; regulation of protein-containing complex assembly [GO:0043254]; regulation of removal of superoxide radicals [GO:2000121]; regulation of toll-like receptor signaling pathway [GO:0034121]; response to fatty acid [GO:0070542]; response to linoleic acid [GO:0070543]; response to lipid [GO:0033993]; response to stilbenoid [GO:0035634]; sensory perception of taste [GO:0050909]; short-chain fatty acid transport [GO:0015912]; triglyceride transport [GO:0034197]" apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; caveola [GO:0005901]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; endocytic vesicle membrane [GO:0030666]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579] amyloid-beta binding [GO:0001540]; fatty acid binding [GO:0005504]; high-density lipoprotein particle binding [GO:0008035]; lipid binding [GO:0008289]; lipoprotein particle binding [GO:0071813]; lipoteichoic acid immune receptor activity [GO:0070892]; long-chain fatty acid transporter activity [GO:0005324]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor activity [GO:0005041]; oleate transmembrane transporter activity [GO:1901480]; oxidised low-density lipoprotein particle receptor activity [GO:0150025]; protein tyrosine kinase activator activity [GO:0030296]; protein-containing complex binding [GO:0044877]; scavenger receptor activity [GO:0005044]; short-chain fatty acid transmembrane transporter activity [GO:0015636]; thrombospondin receptor activity [GO:0070053]; Toll-like receptor binding [GO:0035325]; transforming growth factor beta binding [GO:0050431] 0.95901 -1.7641 ANMFRSQVTGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.35405 0 9.24662 0 10.5884 0 P16870 CBPE_HUMAN Carboxypeptidase E (CPE) (EC 3.4.17.10) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase) CPE Homo sapiens (Human) cardiac left ventricle morphogenesis [GO:0003214]; insulin processing [GO:0030070]; neuropeptide signaling pathway [GO:0007218]; peptide hormone secretion [GO:0030072]; peptide metabolic process [GO:0006518]; protein localization to membrane [GO:0072657]; protein localization to secretory granule [GO:0033366]; protein modification process [GO:0036211]; protein processing [GO:0016485]; Wnt signaling pathway [GO:0016055] extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; transport vesicle membrane [GO:0030658] carboxypeptidase activity [GO:0004180]; cell adhesion molecule binding [GO:0050839]; metallocarboxypeptidase activity [GO:0004181]; molecular function activator activity [GO:0140677]; neurexin family protein binding [GO:0042043]; zinc ion binding [GO:0008270] 0.26778 0.84498 IVDQNTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1069 0 0 0 0 0 0 0 P16871 IL7RA_HUMAN Interleukin-7 receptor subunit alpha (IL-7 receptor subunit alpha) (IL-7R subunit alpha) (IL-7R-alpha) (IL-7RA) (CDw127) (CD antigen CD127) IL7R Homo sapiens (Human) B cell homeostasis [GO:0001782]; B cell proliferation [GO:0042100]; cell morphogenesis [GO:0000902]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-positive bacterium [GO:0050830]; gene expression [GO:0010467]; hemopoiesis [GO:0030097]; immune response [GO:0006955]; lymph node development [GO:0048535]; negative regulation of T cell apoptotic process [GO:0070233]; negative regulation of T cell mediated cytotoxicity [GO:0001915]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of receptor signaling pathway via STAT [GO:1904894]; positive regulation of T cell differentiation in thymus [GO:0033089]; regulation of cell size [GO:0008361]; regulation of DNA recombination [GO:0000018]; signal transduction [GO:0007165]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; T cell mediated cytotoxicity [GO:0001913] clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] antigen binding [GO:0003823]; cytokine receptor activity [GO:0004896]; interleukin-7 receptor activity [GO:0004917] 0.96387 -2.2299 TLEHLCKKPR 0 0 0 0 0 0 0 0 0 0 0 9.13538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P16885 PLCG2_HUMAN "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-2) (Phospholipase C-IV) (PLC-IV) (Phospholipase C-gamma-2) (PLC-gamma-2)" PLCG2 Homo sapiens (Human) "activation of store-operated calcium channel activity [GO:0032237]; antifungal innate immune response [GO:0061760]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; calcium-mediated signaling [GO:0019722]; cell activation [GO:0001775]; cellular response to calcium ion [GO:0071277]; cellular response to lectin [GO:1990858]; cellular response to lipid [GO:0071396]; Fc-epsilon receptor signaling pathway [GO:0038095]; follicular B cell differentiation [GO:0002316]; inositol trisphosphate biosynthetic process [GO:0032959]; intracellular signal transduction [GO:0035556]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage activation involved in immune response [GO:0002281]; negative regulation of programmed cell death [GO:0043069]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; phospholipid catabolic process [GO:0009395]; platelet activation [GO:0030168]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of receptor internalization [GO:0002092]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon production [GO:0032481]; programmed cell death [GO:0012501]; regulation of calcineurin-NFAT signaling cascade [GO:0070884]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of lipid metabolic process [GO:0019216]; release of sequestered calcium ion into cytosol [GO:0051209]; response to axon injury [GO:0048678]; response to yeast [GO:0001878]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; toll-like receptor signaling pathway [GO:0002224]; Wnt signaling pathway [GO:0016055]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular vesicle [GO:0097708]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587] phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipase C activity [GO:0004629]; phosphorylation-dependent protein binding [GO:0140031]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; scaffold protein binding [GO:0097110] 0.96912 -4.461 DKFVEIGAHK 0 0 0 0 0 0 0 9.18483 0 0 0 0 0 0 0 0 0 10.7143 0 0 0 0 0 0 0 8.12557 0 P16949 STMN1_HUMAN Stathmin (Leukemia-associated phosphoprotein p18) (Metablastin) (Oncoprotein 18) (Op18) (Phosphoprotein p19) (pp19) (Prosolin) (Protein Pr22) (pp17) STMN1 C1orf215 LAP18 OP18 Homo sapiens (Human) axonogenesis [GO:0007409]; establishment of skin barrier [GO:0061436]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; intracellular signal transduction [GO:0035556]; microtubule depolymerization [GO:0007019]; mitotic cytokinesis [GO:0000281]; mitotic spindle organization [GO:0007052]; negative regulation of guanyl-nucleotide exchange factor activity [GO:1905098]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; neuron projection development [GO:0031175]; regulation of cell migration [GO:0030334]; regulation of microtubule polymerization or depolymerization [GO:0031110]; response to virus [GO:0009615]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; microtubule [GO:0005874]; neuron projection [GO:0043005] tubulin binding [GO:0015631] 0 4.5353 ASGQAFELILSPR 0 0 0 10.2292 0 0 0 0 9.37286 8.55175 0 0 9.9472 9.66702 9.49669 10.7088 10.5321 9.91569 9.44876 9.29255 9.58148 9.81157 9.93996 10.2259 11.1337 10.7216 11.0564 P17014 ZNF12_HUMAN Zinc finger protein 12 (Gonadotropin-inducible ovary transcription repressor 3) (GIOT-3) (Zinc finger protein 325) (Zinc finger protein KOX3) ZNF12 GIOT3 KOX3 ZNF325 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892] centrosome [GO:0005813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837] 0.92403 -0.9918 AFQKDTVFVNHMEEKPYK 0 0 0 0 0 0 0 0 0 10.6588 0 0 0 0 0 15.994 15.852 0 0 11.4091 0 0 0 0 0 0 0 P17017 ZNF14_HUMAN Zinc finger protein 14 (Gonadotropin-inducible ovary transcription repressor 4) (GIOT-4) (Zinc finger protein KOX6) ZNF14 GIOT4 KOX6 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.95805 -1.6743 AHVIIHTGARPYKCK 0 14.005 0 10.7248 10.6662 0 0 14.2123 0 0 0 9.12443 9.33865 9.61905 9.45588 0 0 11.4423 0 0 0 0 0 0 0 0 10.9249 P17021 ZNF17_HUMAN Zinc finger protein 17 (Zinc finger protein HPF3) (Zinc finger protein KOX10) ZNF17 KIAA1947 KOX10 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.93892 -1.3214 CGKFFRYCFTLNR 0 0 0 0 0 0 0 8.27766 9.19313 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P17024 ZNF20_HUMAN Zinc finger protein 20 (Zinc finger protein KOX13) ZNF20 KOX13 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.88201 -0.30099 AFRCTSDLQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.56697 0 0 0 0 0 0 0 0 P17025 ZN182_HUMAN Zinc finger protein 182 (Zinc finger protein 21) (Zinc finger protein KOX14) ZNF182 KOX14 ZNF21 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96472 -2.3802 EKSKLIIHQR 9.41306 0 0 0 0 0 0 0 0 0 0 9.43093 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1322 0 P17027 ZNF23_HUMAN Zinc finger protein 23 (Zinc finger protein 359) (Zinc finger protein 612) (Zinc finger protein KOX16) ZNF23 KOX16 ZNF359 ZNF612 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837] 0.92736 -1.1929 CNSQFRQHLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0144 0 0 0 0 0 0 P17029 ZKSC1_HUMAN Zinc finger protein with KRAB and SCAN domains 1 (Zinc finger protein 139) (Zinc finger protein 36) (Zinc finger protein KOX18) ZKSCAN1 KOX18 ZNF139 ZNF36 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.92737 -1.193 DKKTITGER 0 0 0 0 0 0 0 0 0 11.1469 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P17030 ZNF25_HUMAN Zinc finger protein 25 (Zinc finger protein KOX19) ZNF25 KOX19 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.95743 -1.6548 TFYYKSDLTK 0 0 0 0 0 0 8.87738 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.56066 0 0 0 0 0 P17031 ZNF26_HUMAN Zinc finger protein 26 (Zinc finger protein KOX20) ZNF26 KOX20 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.94896 -1.3732 NCVCSECGKAFRCK 0 0 0 0 9.20528 0 0 0 0 0 12.6715 0 0 9.61117 0 0 0 0 0 0 0 0 0 0 0 0 0 P17032 ZN37A_HUMAN Zinc finger protein 37A (Zinc finger protein KOX21) ZNF37A KOX21 ZNF37 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.80768 0.22916 GEEPWILEEK 0 0 0 0 0 0 0 0 0 0 0 0 10.0136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P17038 ZNF43_HUMAN Zinc finger protein 43 (Zinc finger protein 39) (Zinc finger protein HTF6) (Zinc finger protein KOX27) ZNF43 KOX27 ZNF39 ZNF39L1 Homo sapiens (Human) nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96194 -2.4565 IIHTRVNFCK 13.1335 0 0 0 0 0 0 10.2495 0 0 0 0 0 8.49001 0 0 0 0 0 0 0 0 0 0 0 0 9.56327 P17050 NAGAB_HUMAN Alpha-N-acetylgalactosaminidase (EC 3.2.1.49) (Alpha-galactosidase B) NAGA Homo sapiens (Human) carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; oligosaccharide metabolic process [GO:0009311] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764] alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803] 0.88015 0.011312 DMGYTYLNIDDCWIGGR 0 11.7661 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P17066 HSP76_HUMAN Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B') HSPA6 HSP70B' Homo sapiens (Human) cellular response to heat [GO:0034605]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein refolding [GO:0042026]; response to unfolded protein [GO:0006986] blood microparticle [GO:0072562]; centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; protein folding chaperone [GO:0044183]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082] 0 27.475 ATAGDTHLGGEDFDNR 12.7448 12.7367 12.6684 0 0 0 11.4692 11.3823 11.1931 13.8704 13.9033 14.4211 11.8521 10.1956 11.0273 10.4433 10.6333 10.8598 10.3075 10.8379 10.546 9.36979 9.3415 9.62366 11.555 11.788 11.413 P17096 HMGA1_HUMAN High mobility group protein HMG-I/HMG-Y (HMG-I(Y)) (High mobility group AT-hook protein 1) (High mobility group protein A1) (High mobility group protein R) HMGA1 HMGIY Homo sapiens (Human) base-excision repair [GO:0006284]; DNA unwinding involved in DNA replication [GO:0006268]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; nucleosome disassembly [GO:0006337]; oncogene-induced cell senescence [GO:0090402]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355] cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575]; senescence-associated heterochromatin focus [GO:0035985]; transcription regulator complex [GO:0005667] "5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; chromatin binding [GO:0003682]; cis-regulatory region sequence-specific DNA binding [GO:0000987]; DNA binding [GO:0003677]; DNA binding, bending [GO:0008301]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; enzyme binding [GO:0019899]; minor groove of adenine-thymine-rich DNA binding [GO:0003680]; molecular adaptor activity [GO:0060090]; molecular function activator activity [GO:0140677]; nuclear receptor coactivator activity [GO:0030374]; nuclear retinoic acid receptor binding [GO:0042974]; nuclear retinoid X receptor binding [GO:0046965]; peroxisome proliferator activated receptor binding [GO:0042975]; RNA binding [GO:0003723]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; structural constituent of chromatin [GO:0030527]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription coregulator binding [GO:0001221]" 0.22714 0.86026 EPSEVPTPK 0 0 8.62695 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P17097 ZNF7_HUMAN Zinc finger protein 7 (Zinc finger protein HF.16) (Zinc finger protein KOX4) ZNF7 KOX4 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.91336 -0.75982 CTECGKAFRLSSK 0 0 0 0 0 0 0 0 8.90893 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P17098 ZNF8_HUMAN Zinc finger protein 8 (Zinc finger protein HF.18) ZNF8 Homo sapiens (Human) BMP signaling pathway [GO:0030509]; negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] DNA binding [GO:0003677]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; zinc ion binding [GO:0008270] 0.9587 -1.866 EGFPTDAPYPTTLGKDR 10.2316 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.89614 10.605 0 9.02871 0 0 P17174 AATC_HUMAN "Aspartate aminotransferase, cytoplasmic (cAspAT) (EC 2.6.1.1) (EC 2.6.1.3) (Cysteine aminotransferase, cytoplasmic) (Cysteine transaminase, cytoplasmic) (cCAT) (Glutamate oxaloacetate transaminase 1) (Transaminase A)" GOT1 Homo sapiens (Human) 2-oxoglutarate metabolic process [GO:0006103]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular response to insulin stimulus [GO:0032869]; fatty acid homeostasis [GO:0055089]; gluconeogenesis [GO:0006094]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; glycerol biosynthetic process [GO:0006114]; Notch signaling pathway [GO:0007219]; oxaloacetate metabolic process [GO:0006107]; response to glucocorticoid [GO:0051384] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634] L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-cysteine transaminase activity [GO:0047801]; phosphatidylserine decarboxylase activity [GO:0004609]; pyridoxal phosphate binding [GO:0030170] 0 26.7 APPSVFAEVPQAQPVLVFK 0 0 0 0 0 0 9.25375 10.1107 0 0 0 0 0 0 0 0 9.68085 0 0 0 0 0 0 0 10.6219 11.1132 10.0342 P17181 INAR1_HUMAN Interferon alpha/beta receptor 1 (IFN-R-1) (IFN-alpha/beta receptor 1) (Cytokine receptor class-II member 1) (Cytokine receptor family 2 member 1) (CRF2-1) (Type I interferon receptor 1) IFNAR1 IFNAR Homo sapiens (Human) cellular response to interferon-alpha [GO:0035457]; cellular response to interferon-beta [GO:0035458]; cellular response to virus [GO:0098586]; positive regulation of cellular respiration [GO:1901857]; receptor signaling pathway via JAK-STAT [GO:0007259]; response to lipopolysaccharide [GO:0032496]; response to virus [GO:0009615]; type I interferon-mediated signaling pathway [GO:0060337] late endosome [GO:0005770]; lysosome [GO:0005764]; plasma membrane [GO:0005886] cytokine binding [GO:0019955]; JAK pathway signal transduction adaptor activity [GO:0008269]; type I interferon binding [GO:0019962]; type I interferon receptor activity [GO:0004905] 0.96759 -2.7958 IENIYSRHK 0 0 9.7625 0 0 0 0 0 0 0 9.79952 0 11.1993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P17252 KPCA_HUMAN Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13) PRKCA PKCA PRKACA Homo sapiens (Human) angiogenesis [GO:0001525]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; desmosome assembly [GO:0002159]; intracellular signal transduction [GO:0035556]; mitotic nuclear membrane disassembly [GO:0007077]; negative regulation of glial cell apoptotic process [GO:0034351]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0106071]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of bone resorption [GO:0045780]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of dense core granule biogenesis [GO:2000707]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of mitotic cell cycle [GO:0045931]; post-translational protein modification [GO:0043687]; protein phosphorylation [GO:0006468]; regulation of mRNA stability [GO:0043488]; regulation of platelet aggregation [GO:0090330]; response to interleukin-1 [GO:0070555] alphav-beta3 integrin-PKCalpha complex [GO:0035866]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; calcium-dependent protein kinase C activity [GO:0004698]; enzyme binding [GO:0019899]; histone H3T6 kinase activity [GO:0035403]; integrin binding [GO:0005178]; protein kinase activity [GO:0004672]; protein kinase C activity [GO:0004697]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; zinc ion binding [GO:0008270] 0.96312 -2.1246 EHAFFRRIDWEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.8771 0 0 0 0 0 0 0 0 0 0 0 P17275 JUNB_HUMAN Transcription factor JunB (Transcription factor AP-1 subunit JunB) JUNB Homo sapiens (Human) cellular response to calcium ion [GO:0071277]; decidualization [GO:0046697]; embryonic process involved in female pregnancy [GO:0060136]; integrated stress response signaling [GO:0140467]; labyrinthine layer blood vessel development [GO:0060716]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; osteoclast differentiation [GO:0030316]; osteoclast proliferation [GO:0002158]; positive regulation of cell differentiation [GO:0045597]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of T-helper 17 cell differentiation [GO:2000319]; regulation of transcription by RNA polymerase II [GO:0006357]; trophectodermal cell differentiation [GO:0001829]; vasculogenesis [GO:0001570] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575]; transcription factor AP-1 complex [GO:0035976]; transcription regulator complex [GO:0005667] "DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.84233 0.15187 ALDDLHK 0 0 0 0 0 0 0 0 0 0 11.4555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P17301 ITA2_HUMAN Integrin alpha-2 (CD49 antigen-like family member B) (Collagen receptor) (Platelet membrane glycoprotein Ia) (GPIa) (VLA-2 subunit alpha) (CD antigen CD49b) ITGA2 CD49B Homo sapiens (Human) "animal organ morphogenesis [GO:0009887]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; collagen-activated signaling pathway [GO:0038065]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; establishment of protein localization [GO:0045184]; female pregnancy [GO:0007565]; focal adhesion assembly [GO:0048041]; hepatocyte differentiation [GO:0070365]; hypotonic response [GO:0006971]; integrin-mediated signaling pathway [GO:0007229]; mammary gland development [GO:0030879]; mesodermal cell differentiation [GO:0048333]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell projection organization [GO:0031346]; positive regulation of collagen binding [GO:0033343]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of translation [GO:0045727]; positive regulation of transmission of nerve impulse [GO:0051971]; response to amine [GO:0014075]; response to hypoxia [GO:0001666]; response to L-ascorbic acid [GO:0033591]; response to muscle activity [GO:0014850]; response to parathyroid hormone [GO:0071107]; response to xenobiotic stimulus [GO:0009410]; skin morphogenesis [GO:0043589]; substrate-dependent cell migration [GO:0006929]" axon terminus [GO:0043679]; basal part of cell [GO:0045178]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha2-beta1 complex [GO:0034666]; integrin complex [GO:0008305]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] amyloid-beta binding [GO:0001540]; collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; collagen receptor activity [GO:0038064]; heparan sulfate proteoglycan binding [GO:0043395]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; virus receptor activity [GO:0001618] 0.89727 -0.58415 ILGSDGAFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3223 0 0 0 11.3113 0 0 0 0 0 0 0 P17342 ANPRC_HUMAN Atrial natriuretic peptide receptor 3 (Atrial natriuretic peptide clearance receptor) (Atrial natriuretic peptide receptor type C) (ANP-C) (ANPR-C) (NPR-C) NPR3 ANPRC C5orf23 NPRC Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; angiogenesis [GO:0001525]; blood vessel remodeling [GO:0001974]; negative regulation of adenylate cyclase activity [GO:0007194]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of smooth muscle cell proliferation [GO:0048662]; osteoclast proliferation [GO:0002158]; pancreatic juice secretion [GO:0030157]; phosphatidylinositol-mediated signaling [GO:0048015]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of urine volume [GO:0035810]; regulation of blood pressure [GO:0008217]; regulation of osteoblast proliferation [GO:0033688]; response to ischemia [GO:0002931]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; vasodilation [GO:0042311] extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] chloride ion binding [GO:0031404]; G protein-coupled peptide receptor activity [GO:0008528]; hormone binding [GO:0042562]; natriuretic peptide receptor activity [GO:0016941]; peptide binding [GO:0042277]; peptide hormone binding [GO:0017046]; protein homodimerization activity [GO:0042803] 0.84873 0.15439 EALPPQK 8.79494 0 0 0 0 0 9.27561 9.144 0 0 0 9.41359 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P17480 UBF1_HUMAN Nucleolar transcription factor 1 (Autoantigen NOR-90) (Upstream-binding factor 1) (UBF-1) UBTF UBF UBF1 Homo sapiens (Human) positive regulation of transcription by RNA polymerase I [GO:0045943]; transcription by RNA polymerase I [GO:0006360]; transcription initiation at RNA polymerase I promoter [GO:0006361] fibrillar center [GO:0001650]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; RNA binding [GO:0003723]; RNA polymerase I cis-regulatory region sequence-specific DNA binding [GO:0001165]; RNA polymerase I core promoter sequence-specific DNA binding [GO:0001164]; RNA polymerase I general transcription initiation factor activity [GO:0001181]; scaffold protein binding [GO:0097110] 0.96995 -4.3777 EKLMWIKK 0 10.6686 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7204 0 0 0 0 0 0 0 9.44313 0 9.86104 0 P17481 HXB8_HUMAN Homeobox protein Hox-B8 (Homeobox protein Hox-2.4) (Homeobox protein Hox-2D) HOXB8 HOX2D Homo sapiens (Human) adult locomotory behavior [GO:0008344]; anterior/posterior pattern specification [GO:0009952]; dorsal spinal cord development [GO:0021516]; embryonic skeletal system morphogenesis [GO:0048704]; grooming behavior [GO:0007625]; negative regulation of myeloid cell differentiation [GO:0045638]; regulation of transcription by RNA polymerase II [GO:0006357]; sensory perception of pain [GO:0019233] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.94845 -1.3617 QKLERAPEAADEGDAQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5681 0 0 0 0 0 0 P17482 HXB9_HUMAN Homeobox protein Hox-B9 (Homeobox protein Hox-2.5) (Homeobox protein Hox-2E) HOXB9 HOX2E Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; cell chemotaxis [GO:0060326]; embryonic skeletal system morphogenesis [GO:0048704]; mammary gland development [GO:0030879]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proximal/distal pattern formation [GO:0009954]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.83478 0.19186 TWLEPAPR 0 0 0 0 0 0 0 0 0 0 0 10.0093 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P17483 HXB4_HUMAN Homeobox protein Hox-B4 (Homeobox protein Hox-2.6) (Homeobox protein Hox-2F) HOXB4 HOX2F Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; bone marrow development [GO:0048539]; definitive hemopoiesis [GO:0060216]; embryonic skeletal system morphogenesis [GO:0048704]; hematopoietic stem cell differentiation [GO:0060218]; hematopoietic stem cell proliferation [GO:0071425]; morphogenesis of an epithelial sheet [GO:0002011]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of stem cell differentiation [GO:2000738]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; somatic stem cell division [GO:0048103]; spleen development [GO:0048536] centrosome [GO:0005813]; chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96131 -2.5603 AACTVQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.49418 8.80096 0 0 0 0 P17509 HXB6_HUMAN Homeobox protein Hox-B6 (Homeobox protein Hox-2.2) (Homeobox protein Hox-2B) (Homeobox protein Hu-2) HOXB6 HOX2B Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; embryonic skeletal system morphogenesis [GO:0048704]; erythrocyte homeostasis [GO:0034101]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA binding [GO:0003723]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.86958 0.052353 HYPAPYGPGPGQDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1983 0 P17540 KCRS_HUMAN "Creatine kinase S-type, mitochondrial (EC 2.7.3.2) (Basic-type mitochondrial creatine kinase) (Mib-CK) (Sarcomeric mitochondrial creatine kinase) (S-MtCK)" CKMT2 Homo sapiens (Human) muscle contraction [GO:0006936]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; creatine kinase activity [GO:0004111] 0.91615 -0.76357 VPPPLPQFGKK 0 0 0 0 0 0 0 0 0 0 0 0 9.81887 9.67442 9.65785 0 0 0 0 0 0 0 0 0 0 0 0 P17542 TAL1_HUMAN T-cell acute lymphocytic leukemia protein 1 (TAL-1) (Class A basic helix-loop-helix protein 17) (bHLHa17) (Stem cell protein) (T-cell leukemia/lymphoma protein 5) TAL1 BHLHA17 SCL TCL5 Homo sapiens (Human) angiogenesis [GO:0001525]; astrocyte fate commitment [GO:0060018]; basophil differentiation [GO:0030221]; cell fate commitment [GO:0045165]; definitive hemopoiesis [GO:0060216]; embryonic hemopoiesis [GO:0035162]; erythrocyte differentiation [GO:0030218]; erythrocyte maturation [GO:0043249]; hemangioblast cell differentiation [GO:0060217]; hematopoietic stem cell differentiation [GO:0060218]; hemopoiesis [GO:0030097]; locomotory behavior [GO:0007626]; megakaryocyte development [GO:0035855]; megakaryocyte differentiation [GO:0030219]; negative regulation of transcription by RNA polymerase II [GO:0000122]; platelet formation [GO:0030220]; positive regulation of cell division [GO:0051781]; positive regulation of chromatin organization [GO:1905269]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of protein-containing complex assembly [GO:0031334]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell population proliferation [GO:0042127]; regulation of mast cell differentiation [GO:0060375]; regulation of somatic stem cell population maintenance [GO:1904672]; regulation of transcription by RNA polymerase II [GO:0006357]; spinal cord association neuron differentiation [GO:0021527]; transcription by RNA polymerase II [GO:0006366] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "chromatin binding [GO:0003682]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; E-box binding [GO:0070888]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; protein dimerization activity [GO:0046983]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription cis-regulatory region binding [GO:0000976]" 0.96213 -2.4809 LLNDQEEEGTQRAK 0 0 9.15026 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P17568 NDUB7_HUMAN NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (Cell adhesion protein SQM1) (Complex I-B18) (CI-B18) (NADH-ubiquinone oxidoreductase B18 subunit) NDUFB7 Homo sapiens (Human) "aerobic respiration [GO:0009060]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]" mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial respiratory chain complex I [GO:0005747]; mitochondrion [GO:0005739] NADH dehydrogenase (ubiquinone) activity [GO:0008137] 0.93169 -1.2547 DYVMRMKEFER 0 0 0 0 0 0 0 0 0 0 0 9.4837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P17600 SYN1_HUMAN Synapsin-1 (Brain protein 4.1) (Synapsin I) SYN1 Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; neuron development [GO:0048666]; neurotransmitter secretion [GO:0007269]; regulation of neurotransmitter secretion [GO:0046928]; regulation of synaptic vesicle cycle [GO:0098693]; regulation of synaptic vesicle exocytosis [GO:2000300]; synapse organization [GO:0050808]; synaptic vesicle clustering [GO:0097091] axon [GO:0030424]; cell body [GO:0044297]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of synaptic vesicle membrane [GO:0098850]; Golgi apparatus [GO:0005794]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; presynaptic active zone [GO:0048786]; Schaffer collateral - CA1 synapse [GO:0098685]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; synaptonemal complex [GO:0000795] actin binding [GO:0003779]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; cytoskeletal protein-membrane anchor activity [GO:0106006]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901] 0.91933 -0.89485 MGHAHSGMGKVK 0 0 0 0 0 0 0 0 0 9.41908 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.00056 0 0 P17612 KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11) PRKACA PKACA Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell communication by electrical coupling involved in cardiac conduction [GO:0086064]; cellular response to cold [GO:0070417]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to heat [GO:0034605]; cellular response to parathyroid hormone stimulus [GO:0071374]; cytokine-mediated signaling pathway [GO:0019221]; high-density lipoprotein particle assembly [GO:0034380]; mesoderm formation [GO:0001707]; mRNA processing [GO:0006397]; negative regulation of glycolytic process through fructose-6-phosphate [GO:1904539]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621]; neural tube closure [GO:0001843]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of insulin secretion [GO:0032024]; positive regulation of protein export from nucleus [GO:0046827]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein autophosphorylation [GO:0046777]; protein export from nucleus [GO:0006611]; protein kinase A signaling [GO:0010737]; protein localization to lipid droplet [GO:1990044]; protein phosphorylation [GO:0006468]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cardiac conduction [GO:1903779]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell cycle [GO:0051726]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of heart rate [GO:0002027]; regulation of macroautophagy [GO:0016241]; regulation of osteoblast differentiation [GO:0045667]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of protein binding [GO:0043393]; regulation of protein processing [GO:0070613]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; renal water homeostasis [GO:0003091]; sperm capacitation [GO:0048240] acrosomal vesicle [GO:0001669]; calcium channel complex [GO:0034704]; cAMP-dependent protein kinase complex [GO:0005952]; centrosome [GO:0005813]; ciliary base [GO:0097546]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; sperm flagellum [GO:0036126]; sperm midpiece [GO:0097225] AMP-activated protein kinase activity [GO:0004679]; ATP binding [GO:0005524]; cAMP-dependent protein kinase activity [GO:0004691]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; phosphatase activator activity [GO:0019211]; protein domain specific binding [GO:0019904]; protein kinase A regulatory subunit binding [GO:0034237]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; ubiquitin protein ligase binding [GO:0031625] 0.8826 -0.093754 RFGNLKNGVNDIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.96097 0 0 0 0 0 0 0 0 0 0 0 P17643 TYRP1_HUMAN "5,6-dihydroxyindole-2-carboxylic acid oxidase (DHICA oxidase) (EC 1.14.18.-) (Catalase B) (Glycoprotein 75) (Melanoma antigen gp75) (Tyrosinase-related protein 1) (TRP) (TRP-1) (TRP1)" TYRP1 CAS2 TYRP TYRRP Homo sapiens (Human) acetoacetic acid metabolic process [GO:0043438]; melanin biosynthetic process [GO:0042438]; melanocyte differentiation [GO:0030318]; melanosome organization [GO:0032438]; positive regulation of melanin biosynthetic process [GO:0048023] clathrin-coated endocytic vesicle membrane [GO:0030669]; cytoplasm [GO:0005737]; endosome membrane [GO:0010008]; intracellular vesicle [GO:0097708]; melanosome [GO:0042470]; melanosome membrane [GO:0033162] metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; protein homodimerization activity [GO:0042803]; tyrosinase activity [GO:0004503] 0.93226 -1.2673 YHLLRLEK 0 0 0 11.1583 0 11.4922 0 9.52685 9.79957 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P17655 CAN2_HUMAN Calpain-2 catalytic subunit (EC 3.4.22.53) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M-type) (Calpain large polypeptide L2) (Calpain-2 large subunit) (Millimolar-calpain) (M-calpain) CAPN2 CANPL2 Homo sapiens (Human) behavioral response to pain [GO:0048266]; blastocyst development [GO:0001824]; cellular response to amino acid stimulus [GO:0071230]; cellular response to interferon-beta [GO:0035458]; cellular response to lipopolysaccharide [GO:0071222]; female pregnancy [GO:0007565]; myoblast fusion [GO:0007520]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of neuron death [GO:1901216]; positive regulation of phosphatidylcholine biosynthetic process [GO:2001247]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of cytoskeleton organization [GO:0051493]; regulation of interleukin-6 production [GO:0032675]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612] calpain complex [GO:0110158]; chromatin [GO:0000785]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum [GO:0097038]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143] calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; cysteine-type peptidase activity [GO:0008234]; cytoskeletal protein binding [GO:0008092]; enzyme binding [GO:0019899]; protein-containing complex binding [GO:0044877] 0.96776 -3.6959 ELGPYSSKTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6265 0 10.3921 0 9.94824 10.7466 P17661 DESM_HUMAN Desmin DES Homo sapiens (Human) cytoskeleton organization [GO:0007010]; intermediate filament organization [GO:0045109]; muscle contraction [GO:0006936]; regulation of heart contraction [GO:0008016]; skeletal muscle organ development [GO:0060538] cardiac myofibril [GO:0097512]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fascia adherens [GO:0005916]; intercalated disc [GO:0014704]; intermediate filament [GO:0005882]; intermediate filament cytoskeleton [GO:0045111]; neuromuscular junction [GO:0031594]; nucleus [GO:0005634]; sarcolemma [GO:0042383]; Z disc [GO:0030018] cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; structural constituent of cytoskeleton [GO:0005200] 0.88443 -0.2486 KLLEGEESR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.6773 10.1983 0 P17676 CEBPB_HUMAN CCAAT/enhancer-binding protein beta (C/EBP beta) (Liver activator protein) (LAP) (Liver-enriched inhibitory protein) (LIP) (Nuclear factor NF-IL6) (Transcription factor 5) (TCF-5) CEBPB TCF5 PP9092 Homo sapiens (Human) acute-phase response [GO:0006953]; brown fat cell differentiation [GO:0050873]; cellular response to amino acid stimulus [GO:0071230]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to organic cyclic compound [GO:0071407]; defense response to bacterium [GO:0042742]; embryonic placenta development [GO:0001892]; granuloma formation [GO:0002432]; hepatocyte proliferation [GO:0072574]; immune response [GO:0006955]; inflammatory response [GO:0006954]; integrated stress response signaling [GO:0140467]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; liver regeneration [GO:0097421]; mammary gland epithelial cell differentiation [GO:0060644]; mammary gland epithelial cell proliferation [GO:0033598]; memory [GO:0007613]; myeloid cell development [GO:0061515]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; ovarian follicle development [GO:0001541]; positive regulation of biomineral tissue development [GO:0070169]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of sodium-dependent phosphate transport [GO:2000120]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; regulation of cell differentiation [GO:0045595]; regulation of dendritic cell differentiation [GO:2001198]; regulation of DNA-templated transcription [GO:0006355]; regulation of interleukin-6 production [GO:0032675]; regulation of odontoblast differentiation [GO:1901329]; regulation of osteoclast differentiation [GO:0045670]; regulation of transcription by RNA polymerase II [GO:0006357]; response to endoplasmic reticulum stress [GO:0034976]; T-helper 1 cell activation [GO:0035711]; transcription by RNA polymerase II [GO:0006366] "C/EBP complex [GO:1990647]; CHOP-C/EBP complex [GO:0036488]; chromatin [GO:0000785]; condensed chromosome, centromeric region [GO:0000779]; cytoplasm [GO:0005737]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575]" "chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; kinase binding [GO:0019900]; nuclear glucocorticoid receptor binding [GO:0035259]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]; ubiquitin-like protein ligase binding [GO:0044389]" 0.95434 -1.5118 TVDKHSDEYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.29193 0 P17677 NEUM_HUMAN Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Neural phosphoprotein B-50) (pp46) GAP43 Homo sapiens (Human) astrocyte differentiation [GO:0048708]; axon choice point recognition [GO:0016198]; axon regeneration [GO:0031103]; cell fate commitment [GO:0045165]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; radial glial cell differentiation [GO:0060019]; regulation of filopodium assembly [GO:0051489]; regulation of growth [GO:0040008]; regulation of postsynaptic specialization assembly [GO:0099150]; response to wounding [GO:0009611]; tissue regeneration [GO:0042246] cytoplasm [GO:0005737]; dendrite [GO:0030425]; filopodium membrane [GO:0031527]; GABA-ergic synapse [GO:0098982]; growth cone membrane [GO:0032584]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793] calmodulin binding [GO:0005516]; lysophosphatidic acid binding [GO:0035727]; phosphatidylinositol phosphate binding [GO:1901981]; phosphatidylserine binding [GO:0001786] 0.030837 1.5287 AEDAPAK 0 0 0 0 0 0 0 0 0 9.8967 0 10.7579 0 0 10.5632 0 0 0 0 0 0 9.23458 0 0 0 0 0 P17693 HLAG_HUMAN "HLA class I histocompatibility antigen, alpha chain G (HLA G antigen) (MHC class I antigen G) [Cleaved into: Soluble HLA class I histocompatibility antigen, alpha chain G (sHLA-G)]" HLA-G HLA-6.0 HLAG Homo sapiens (Human) "antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent [GO:0002486]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cellular defense response [GO:0006968]; immune response [GO:0006955]; immune response-inhibiting cell surface receptor signaling pathway [GO:0002767]; negative regulation of angiogenesis [GO:0016525]; negative regulation of dendritic cell differentiation [GO:2001199]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of immune response [GO:0050777]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of T cell mediated cytotoxicity [GO:0001915]; negative regulation of T cell proliferation [GO:0042130]; peripheral B cell tolerance induction [GO:0002451]; positive regulation of cellular senescence [GO:2000774]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of natural killer cell cytokine production [GO:0002729]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of T cell tolerance induction [GO:0002666]; positive regulation of tolerance induction [GO:0002645]; protection from natural killer cell mediated cytotoxicity [GO:0042270]; protein homotrimerization [GO:0070207]" cis-Golgi network membrane [GO:0033106]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium membrane [GO:0031527]; Golgi membrane [GO:0000139]; lumenal side of endoplasmic reticulum membrane [GO:0098553]; membrane [GO:0016020]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038] CD8 receptor binding [GO:0042610]; identical protein binding [GO:0042802]; peptide antigen binding [GO:0042605]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102] 0.82926 0.20511 THVTHHPVFDYEATLR 0 0 0 0 0 0 0 0 9.77189 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P17706 PTN2_HUMAN Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP) PTPN2 PTPT Homo sapiens (Human) B cell differentiation [GO:0030183]; erythrocyte differentiation [GO:0030218]; glucose homeostasis [GO:0042593]; insulin receptor recycling [GO:0038020]; insulin receptor signaling pathway [GO:0008286]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemotaxis [GO:0050922]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of inflammatory response [GO:0050728]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of interleukin-2-mediated signaling pathway [GO:1902206]; negative regulation of interleukin-4-mediated signaling pathway [GO:1902215]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage colony-stimulating factor signaling pathway [GO:1902227]; negative regulation of macrophage differentiation [GO:0045650]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of positive thymic T cell selection [GO:1902233]; negative regulation of protein tyrosine kinase activity [GO:0061099]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; negative regulation of type II interferon-mediated signaling pathway [GO:0060336]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of PERK-mediated unfolded protein response [GO:1903899]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of type II interferon-mediated signaling pathway [GO:0060334]; T cell differentiation [GO:0030217] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endosome lumen [GO:0031904]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] integrin binding [GO:0005178]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; STAT family protein binding [GO:0097677]; syntaxin binding [GO:0019905] 0.96904 -3.0229 IGLEEEKLTGDR 0 0 10.8584 10.1171 0 0 0 0 10.5039 0 0 0 0 0 0 0 10.5836 0 0 0 0 9.21167 9.10245 0 0 0 0 P17707 DCAM_HUMAN S-adenosylmethionine decarboxylase proenzyme (AdoMetDC) (SAMDC) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain] AMD1 AMD Homo sapiens (Human) polyamine metabolic process [GO:0006595]; S-adenosylmethionine metabolic process [GO:0046500]; spermidine biosynthetic process [GO:0008295]; spermine biosynthetic process [GO:0006597] cytosol [GO:0005829] adenosylmethionine decarboxylase activity [GO:0004014]; identical protein binding [GO:0042802]; putrescine binding [GO:0019810] 0.91774 -0.85425 MEAAHFFEGTEKLLEVWFSR 0 0 0 0 0 0 0 0 0 0 0 9.88608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P17752 TPH1_HUMAN Tryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 1) TPH1 TPH TPRH TRPH Homo sapiens (Human) aromatic amino acid metabolic process [GO:0009072]; bone remodeling [GO:0046849]; circadian rhythm [GO:0007623]; mammary gland alveolus development [GO:0060749]; negative regulation of ossification [GO:0030279]; platelet degranulation [GO:0002576]; positive regulation of fat cell differentiation [GO:0045600]; regulation of hemostasis [GO:1900046]; response to immobilization stress [GO:0035902]; serotonin biosynthetic process [GO:0042427] cytosol [GO:0005829]; neuron projection [GO:0043005] iron ion binding [GO:0005506]; tryptophan 5-monooxygenase activity [GO:0004510] 0.96923 -3.3819 EQLNDIFHLLK 0 0 0 0 0 0 0 0 0 10.9058 10.7489 10.988 0 0 9.8855 0 0 9.91234 0 0 0 0 0 0 0 0 0 P17813 EGLN_HUMAN Endoglin (CD antigen CD105) ENG END Homo sapiens (Human) artery morphogenesis [GO:0048844]; atrial cardiac muscle tissue morphogenesis [GO:0055009]; atrioventricular canal morphogenesis [GO:1905222]; BMP signaling pathway [GO:0030509]; bone development [GO:0060348]; branching involved in blood vessel morphogenesis [GO:0001569]; cardiac atrium morphogenesis [GO:0003209]; cardiac ventricle morphogenesis [GO:0003208]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell migration involved in endocardial cushion formation [GO:0003273]; cell motility [GO:0048870]; cellular response to mechanical stimulus [GO:0071260]; central nervous system vasculogenesis [GO:0022009]; detection of hypoxia [GO:0070483]; dorsal aorta morphogenesis [GO:0035912]; endocardial cushion morphogenesis [GO:0003203]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; extracellular matrix constituent secretion [GO:0070278]; extracellular matrix disassembly [GO:0022617]; heart looping [GO:0001947]; negative regulation of cell migration [GO:0030336]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of gene expression [GO:0010629]; negative regulation of nitric-oxide synthase activity [GO:0051001]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of angiogenesis [GO:0045766]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation [GO:1905007]; positive regulation of gene expression [GO:0010628]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of systemic arterial blood pressure [GO:0003084]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular associated smooth muscle cell differentiation [GO:1905065]; regulation of cell adhesion [GO:0030155]; regulation of cell population proliferation [GO:0042127]; regulation of DNA-templated transcription [GO:0006355]; regulation of phosphorylation [GO:0042325]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; response to corticosteroid [GO:0031960]; response to hypoxia [GO:0001666]; response to xenobiotic stimulus [GO:0009410]; smooth muscle tissue development [GO:0048745]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular associated smooth muscle cell development [GO:0097084]; vasculogenesis [GO:0001570]; venous blood vessel morphogenesis [GO:0048845]; ventricular trabecula myocardium morphogenesis [GO:0003222]; wound healing [GO:0042060] cell surface [GO:0009986]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] activin binding [GO:0048185]; coreceptor activity [GO:0015026]; galactose binding [GO:0005534]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; transforming growth factor beta binding [GO:0050431]; transmembrane signaling receptor activity [GO:0004888]; type I transforming growth factor beta receptor binding [GO:0034713]; type II transforming growth factor beta receptor binding [GO:0005114] 0.7704 0.27422 TLEWRPR 0 0 0 0 0 0 0 0 0 0 0 0 10.2981 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P17844 DDX5_HUMAN Probable ATP-dependent RNA helicase DDX5 (EC 3.6.4.13) (DEAD box protein 5) (RNA helicase p68) DDX5 G17P1 HELR HLR1 Homo sapiens (Human) "alternative mRNA splicing, via spliceosome [GO:0000380]; androgen receptor signaling pathway [GO:0030521]; BMP signaling pathway [GO:0030509]; epithelial to mesenchymal transition [GO:0001837]; intracellular estrogen receptor signaling pathway [GO:0030520]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; miRNA transcription [GO:0061614]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transcription [GO:0009299]; myoblast differentiation [GO:0045445]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear-transcribed mRNA catabolic process [GO:0000956]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; primary miRNA processing [GO:0031053]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of osteoblast differentiation [GO:0045667]; regulation of skeletal muscle cell differentiation [GO:2001014]; regulation of transcription by RNA polymerase II [GO:0006357]; rhythmic process [GO:0048511]" catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; MH2 domain binding [GO:0035500]; mRNA 3'-UTR binding [GO:0003730]; nuclear androgen receptor binding [GO:0050681]; pre-mRNA binding [GO:0036002]; primary miRNA binding [GO:0070878]; promoter-specific chromatin binding [GO:1990841]; R-SMAD binding [GO:0070412]; ribonucleoprotein complex binding [GO:0043021]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; SMAD binding [GO:0046332] 0.85767 0.10063 AGPLSGK 0 14.2937 0 0 0 13.95 0 0 0 9.35273 9.19476 14.878 0 0 0 10.0616 9.85624 0 10.103 0 0 0 0 0 0 0 10.5065 P17858 PFKAL_HUMAN "ATP-dependent 6-phosphofructokinase, liver type (ATP-PFK) (PFK-L) (EC 2.7.1.11) (6-phosphofructokinase type B) (Phosphofructo-1-kinase isozyme B) (PFK-B) (Phosphohexokinase)" PFKL Homo sapiens (Human) "canonical glycolysis [GO:0061621]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose 6-phosphate metabolic process [GO:0006002]; glycolytic process [GO:0006096]; negative regulation of insulin secretion [GO:0046676]; response to glucose [GO:0009749]" 6-phosphofructokinase complex [GO:0005945]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; secretory granule lumen [GO:0034774] 6-phosphofructokinase activity [GO:0003872]; AMP binding [GO:0016208]; ATP binding [GO:0005524]; fructose binding [GO:0070061]; fructose-6-phosphate binding [GO:0070095]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029] 0.96734 -3.7991 AFTTREGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.26254 0 0 0 0 0 0 P17980 PRS6A_HUMAN 26S proteasome regulatory subunit 6A (26S proteasome AAA-ATPase subunit RPT5) (Proteasome 26S subunit ATPase 3) (Proteasome subunit P50) (Tat-binding protein 1) (TBP-1) PSMC3 TBP1 Homo sapiens (Human) modulation by host of viral transcription [GO:0043921]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] "cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; proteasome accessory complex [GO:0022624]; proteasome complex [GO:0000502]; proteasome regulatory particle, base subcomplex [GO:0008540]; secretory granule lumen [GO:0034774]" ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; identical protein binding [GO:0042802]; proteasome-activating activity [GO:0036402] 0.69629 0.38051 FDSEKAGDREVQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.8025 0 0 0 0 0 0 0 0 0 P17987 TCPA_HUMAN T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) TCP1 CCT1 CCTA Homo sapiens (Human) binding of sperm to zona pellucida [GO:0007339]; chaperone-mediated protein folding [GO:0061077]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of protein localization to Cajal body [GO:1904871]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; regulation of macrophage apoptotic process [GO:2000109]; scaRNA localization to Cajal body [GO:0090666]; toxin transport [GO:1901998]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053]; tubulin complex assembly [GO:0007021] acrosomal vesicle [GO:0001669]; cell body [GO:0044297]; centrosome [GO:0005813]; chaperonin-containing T-complex [GO:0005832]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; heterochromatin [GO:0000792]; microtubule [GO:0005874]; pericentriolar material [GO:0000242]; zona pellucida receptor complex [GO:0002199] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082] 0 35.935 AFHNEAQVNPER 8.95251 9.8049 9.85515 0 0 0 10.928 9.46653 10.3048 9.85072 9.73249 9.06889 0 0 0 9.64886 9.59924 0 9.42295 9.62912 0 0 0 0 9.98584 9.48246 0 P18031 PTN1_HUMAN Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) PTPN1 PTP1B Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor recycling [GO:0038020]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338] cytoplasm [GO:0005737]; cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endosome lumen [GO:0031904]; mitochondrial crista [GO:0030061]; mitochondrial matrix [GO:0005759]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443] cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270] 0.96005 -1.8988 FIMGDSSVQDQWK 9.02544 0 12.4773 0 0 0 0 0 0 12.2107 0 0 0 8.85156 0 0 0 0 0 0 0 0 0 0 0 0 0 P18054 LOX12_HUMAN Polyunsaturated fatty acid lipoxygenase ALOX12 (EC 1.13.11.-) (Arachidonate (12S)-lipoxygenase) (12S-LOX) (12S-lipoxygenase) (EC 1.13.11.31) (Arachidonate (15S)-lipoxygenase) (EC 1.13.11.33) (Linoleate (13S)-lipoxygenase) (Lipoxin synthase 12-LO) (EC 3.3.2.-) (Platelet-type lipoxygenase 12) ALOX12 12LO LOG12 Homo sapiens (Human) arachidonic acid metabolic process [GO:0019369]; establishment of skin barrier [GO:0061436]; fatty acid oxidation [GO:0019395]; hepoxilin biosynthetic process [GO:0051122]; leukotriene A4 metabolic process [GO:1901751]; linoleic acid metabolic process [GO:0043651]; lipid metabolic process [GO:0006629]; lipid oxidation [GO:0034440]; lipoxin A4 biosynthetic process [GO:2001303]; lipoxin B4 biosynthetic process [GO:2001306]; lipoxygenase pathway [GO:0019372]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of platelet aggregation [GO:0090331]; superoxide anion generation [GO:0042554]; unsaturated fatty acid metabolic process [GO:0033559] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; sarcolemma [GO:0042383] arachidonate 12(S)-lipoxygenase activity [GO:0004052]; arachidonate 15-lipoxygenase activity [GO:0050473]; hepoxilin-epoxide hydrolase activity [GO:0047977]; iron ion binding [GO:0005506]; linoleate 13S-lipoxygenase activity [GO:0016165] 0.94494 -1.3417 RQPDMVPLGHHKEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6719 0 0 0 P18065 IBP2_HUMAN Insulin-like growth factor-binding protein 2 (IBP-2) (IGF-binding protein 2) (IGFBP-2) IGFBP2 BP2 IBP2 Homo sapiens (Human) aging [GO:0007568]; cellular response to hormone stimulus [GO:0032870]; female pregnancy [GO:0007565]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of activated T cell proliferation [GO:0042104]; regulation of insulin-like growth factor receptor signaling pathway [GO:0043567]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to glucocorticoid [GO:0051384]; response to lithium ion [GO:0010226]; response to mechanical stimulus [GO:0009612]; response to nutrient [GO:0007584]; response to retinoic acid [GO:0032526]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165] apical plasma membrane [GO:0016324]; cytoplasmic vesicle [GO:0031410]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615] insulin-like growth factor I binding [GO:0031994]; insulin-like growth factor II binding [GO:0031995]; signaling receptor binding [GO:0005102] 0.9594 -1.8861 ISTMRLPDER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8271 0 0 0 0 9.68438 0 0 10.6703 P18074 ERCC2_HUMAN General transcription and DNA repair factor IIH helicase subunit XPD (TFIIH subunit XPD) (EC 3.6.4.12) (Basic transcription factor 2 80 kDa subunit) (BTF2 p80) (CXPD) (DNA excision repair protein ERCC-2) (DNA repair protein complementing XP-D cells) (TFIIH basal transcription factor complex 80 kDa subunit) (TFIIH 80 kDa subunit) (TFIIH p80) (Xeroderma pigmentosum group D-complementing protein) ERCC2 XPD XPDC Homo sapiens (Human) "apoptotic process [GO:0006915]; bone mineralization [GO:0030282]; central nervous system myelin formation [GO:0032289]; chromosome segregation [GO:0007059]; determination of adult lifespan [GO:0008340]; embryonic cleavage [GO:0040016]; erythrocyte maturation [GO:0043249]; extracellular matrix organization [GO:0030198]; hair cell differentiation [GO:0035315]; hair follicle maturation [GO:0048820]; hematopoietic stem cell differentiation [GO:0060218]; hematopoietic stem cell proliferation [GO:0071425]; in utero embryonic development [GO:0001701]; insulin-like growth factor receptor signaling pathway [GO:0048009]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; multicellular organism growth [GO:0035264]; nucleotide-excision repair [GO:0006289]; positive regulation of DNA binding [GO:0043388]; positive regulation of mitotic recombination [GO:0045951]; post-embryonic development [GO:0009791]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to oxidative stress [GO:0006979]; spinal cord development [GO:0021510]; transcription by RNA polymerase II [GO:0006366]; transcription elongation by RNA polymerase I [GO:0006362]; transcription-coupled nucleotide-excision repair [GO:0006283]; UV protection [GO:0009650]" CAK-ERCC2 complex [GO:0070516]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; MMXD complex [GO:0071817]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIH core complex [GO:0000439]; transcription factor TFIIH holo complex [GO:0005675] "4 iron, 4 sulfur cluster binding [GO:0051539]; 5'-3' DNA helicase activity [GO:0043139]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; damaged DNA binding [GO:0003684]; DNA helicase activity [GO:0003678]; metal ion binding [GO:0046872]; protein-macromolecule adaptor activity [GO:0030674]" 0.8904 -0.50183 CHSLTASYVR 0 0 0 0 0 0 0 10.6002 10.6158 0 0 0 0 0 9.49478 0 0 0 0 0 0 0 0 0 9.15783 0 0 P18077 RL35A_HUMAN Large ribosomal subunit protein eL33 (60S ribosomal protein L35a) (Cell growth-inhibiting gene 33 protein) RPL35A GIG33 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; ribosomal large subunit biogenesis [GO:0042273]; rRNA processing [GO:0006364]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; extracellular exosome [GO:0070062]; membrane [GO:0016020] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049] 0.78883 0.24997 EHTALLK 0 9.17508 0 0 0 0 8.95989 0 0 0 0 0 0 0 0 0 0 0 0 0 8.44659 0 0 0 0 0 0 P18085 ARF4_HUMAN ADP-ribosylation factor 4 ARF4 ARF2 Homo sapiens (Human) "activation of phospholipase D activity [GO:0031584]; apical protein localization [GO:0045176]; cell migration [GO:0016477]; cilium assembly [GO:0060271]; dendritic spine development [GO:0060996]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular protein transport [GO:0006886]; learning [GO:0007612]; negative regulation of apoptotic process [GO:0043066]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to cilium [GO:0061512]; regulation of postsynapse organization [GO:0099175]; regulation of reactive oxygen species metabolic process [GO:2000377]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; vesicle-mediated transport [GO:0016192]" cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587] epidermal growth factor receptor binding [GO:0005154]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; guanyl-nucleotide exchange factor activity [GO:0005085]; NAD+-protein-arginine ADP-ribosyltransferase activity [GO:0106274] 0 6.7427 ILMVGLDAAGK 9.17058 9.22103 0 0 0 0 8.79912 8.96425 9.49019 10.5412 10.2658 10.3736 10.0678 9.92816 9.92025 10.5769 10.34 10.8351 10.3063 0 10.3137 10.5252 11.664 11.9953 12.4139 10.9856 12.2692 P18089 ADA2B_HUMAN Alpha-2B adrenergic receptor (Alpha-2 adrenergic receptor subtype C2) (Alpha-2B adrenoreceptor) (Alpha-2B adrenoceptor) (Alpha-2BAR) ADRA2B ADRA2L1 ADRA2RL1 Homo sapiens (Human) activation of protein kinase B activity [GO:0032148]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adrenergic receptor signaling pathway [GO:0071875]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; female pregnancy [GO:0007565]; G protein-coupled receptor signaling pathway [GO:0007186]; MAPK cascade [GO:0000165]; negative regulation of epinephrine secretion [GO:0032811]; negative regulation of norepinephrine secretion [GO:0010700]; platelet activation [GO:0030168]; positive regulation of blood pressure [GO:0045777]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of uterine smooth muscle contraction [GO:0070474]; receptor transactivation [GO:0035624]; regulation of vascular associated smooth muscle contraction [GO:0003056] cell surface [GO:0009986]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886] alpha2-adrenergic receptor activity [GO:0004938]; epinephrine binding [GO:0051379] 0.62336 0.41349 EVNGHSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.475 10.6821 0 11.0737 P18124 RL7_HUMAN Large ribosomal subunit protein uL30 (60S ribosomal protein L7) RPL7 Homo sapiens (Human) "cytoplasmic translation [GO:0002181]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; ribosomal large subunit biogenesis [GO:0042273]; rRNA processing [GO:0006364]; translation [GO:0006412]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; ribonucleoprotein complex [GO:1990904] DNA binding [GO:0003677]; identical protein binding [GO:0042802]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0 9.2652 EANNFLWPFK 0 0 0 0 0 0 0 9.16486 8.93961 0 0 8.55689 0 10.2048 0 0 10.8409 10.6177 9.5182 0 0 9.56459 0 0 12.2619 11.729 0 P18206 VINC_HUMAN Vinculin (Metavinculin) (MV) VCL Homo sapiens (Human) adherens junction assembly [GO:0034333]; apical junction assembly [GO:0043297]; axon extension [GO:0048675]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; epithelial cell-cell adhesion [GO:0090136]; lamellipodium assembly [GO:0030032]; maintenance of blood-brain barrier [GO:0035633]; morphogenesis of an epithelium [GO:0002009]; negative regulation of cell migration [GO:0030336]; platelet aggregation [GO:0070527]; protein localization to cell surface [GO:0034394]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of focal adhesion assembly [GO:0051893]; regulation of protein localization to adherens junction [GO:1904702] adherens junction [GO:0005912]; brush border [GO:0005903]; cell projection [GO:0042995]; cell-cell contact zone [GO:0044291]; cell-cell junction [GO:0005911]; cell-substrate junction [GO:0030055]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular vesicle [GO:1903561]; fascia adherens [GO:0005916]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inner dense plaque of desmosome [GO:0090637]; membrane raft [GO:0045121]; outer dense plaque of desmosome [GO:0090636]; plasma membrane [GO:0005886]; podosome ring [GO:0061826]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]; terminal web [GO:1990357]; zonula adherens [GO:0005915] actin binding [GO:0003779]; alpha-catenin binding [GO:0045294]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; dystroglycan binding [GO:0002162]; molecular adaptor activity [GO:0060090]; structural molecule activity [GO:0005198]; ubiquitin protein ligase binding [GO:0031625] 0.13228 1.0594 AVAGNISDPGLQK 8.49933 8.7186 10.958 9.07114 0 0 0 0 0 10.9626 8.57153 9.17911 12.202 0 0 8.77883 0 13.0451 0 0 9.41327 0 0 0 11.6475 0 0 P18283 GPX2_HUMAN Glutathione peroxidase 2 (GPx-2) (GSHPx-2) (EC 1.11.1.9) (Gastrointestinal glutathione peroxidase) (Glutathione peroxidase-gastrointestinal) (GPx-GI) (GSHPx-GI) (Glutathione peroxidase-related protein 2) (GPRP-2) GPX2 Homo sapiens (Human) response to oxidative stress [GO:0006979] cytoplasm [GO:0005737]; cytosol [GO:0005829] electron transfer activity [GO:0009055]; glutathione peroxidase activity [GO:0004602] 0.61143 0.43302 FLIGPEGEPFR 0 0 0 0 0 0 11.1817 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0592 9.94604 0 0 0 0 11.4001 P18428 LBP_HUMAN Lipopolysaccharide-binding protein (LBP) LBP Homo sapiens (Human) acute-phase response [GO:0006953]; cell surface pattern recognition receptor signaling pathway [GO:0002752]; cellular defense response [GO:0006968]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of molecule of bacterial origin [GO:0032490]; innate immune response [GO:0045087]; leukocyte chemotaxis involved in inflammatory response [GO:0002232]; lipopolysaccharide transport [GO:0015920]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage activation involved in immune response [GO:0002281]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil chemotaxis [GO:0030593]; opsonization [GO:0008228]; positive regulation of chemokine production [GO:0032722]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage activation [GO:0043032]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of respiratory burst involved in inflammatory response [GO:0060265]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; positive regulation of tumor necrosis factor production [GO:0032760]; response to lipopolysaccharide [GO:0032496] cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020] coreceptor activity [GO:0015026]; lipopeptide binding [GO:0071723]; lipopolysaccharide binding [GO:0001530]; lipoteichoic acid binding [GO:0070891]; signaling receptor binding [GO:0005102] 0.92201 -1.1039 VQGRWKVR 0 0 0 0 0 0 0 0 10.4268 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P18433 PTPRA_HUMAN Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48) PTPRA PTPA PTPRL2 Homo sapiens (Human) insulin receptor signaling pathway [GO:0008286]; integrin-mediated signaling pathway [GO:0007229]; modulation of chemical synaptic transmission [GO:0050804]; protein dephosphorylation [GO:0006470]; protein phosphorylation [GO:0006468]; regulation of focal adhesion assembly [GO:0051893] extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; Schaffer collateral - CA1 synapse [GO:0098685]; synaptic membrane [GO:0097060] protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001] 0.96353 -2.1133 DLLVTNTRENKSR 0 0 11.4225 0 0 0 0 0 0 0 0 9.75477 0 0 0 0 14.0276 0 9.85414 0 0 10.2667 0 9.05742 0 0 0 P18440 ARY1_HUMAN Arylamine N-acetyltransferase 1 (EC 2.3.1.5) (Arylamide acetylase 1) (Monomorphic arylamine N-acetyltransferase) (MNAT) (N-acetyltransferase type 1) (NAT-1) NAT1 AAC1 Homo sapiens (Human) xenobiotic metabolic process [GO:0006805] cytosol [GO:0005829] arylamine N-acetyltransferase activity [GO:0004060] 0.94814 -1.3596 LDLETLTDILQHQIR 10.0821 0 0 0 0 0 10.282 0 0 0 0 10.5463 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P18505 GBRB1_HUMAN Gamma-aminobutyric acid receptor subunit beta-1 (GABA(A) receptor subunit beta-1) GABRB1 Homo sapiens (Human) cellular response to histamine [GO:0071420]; central nervous system neuron development [GO:0021954]; chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; monoatomic ion transmembrane transport [GO:0034220]; monoatomic ion transport [GO:0006811]; nervous system process [GO:0050877]; ovulation cycle [GO:0042698]; regulation of membrane potential [GO:0042391]; response to progesterone [GO:0032570]; response to toxic substance [GO:0009636]; signal transduction [GO:0007165] chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; GABA-A receptor complex [GO:1902711]; GABA-ergic synapse [GO:0098982]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]; postsynaptic specialization membrane [GO:0099634]; presynaptic active zone membrane [GO:0048787]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202] G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential [GO:0150047]; GABA receptor binding [GO:0050811]; GABA-A receptor activity [GO:0004890]; GABA-gated chloride ion channel activity [GO:0022851]; ligand-gated monoatomic ion channel activity [GO:0015276]; ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; neurotransmitter receptor activity [GO:0030594]; transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315] 0.93146 -1.251 IPDLTDVNSIDK 0 0 0 0 0 0 0 0 0 0 11.4631 0 0 0 0 0 0 0 0 0 0 0 9.12032 0 0 0 0 P18509 PACA_HUMAN Pituitary adenylate cyclase-activating polypeptide (PACAP) [Cleaved into: PACAP-related peptide (PRP-48); Pituitary adenylate cyclase-activating polypeptide 27 (PACAP-27) (PACAP27); Pituitary adenylate cyclase-activating polypeptide 38 (PACAP-38) (PACAP38)] ADCYAP1 Homo sapiens (Human) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP-mediated signaling [GO:0019933]; cell-cell signaling [GO:0007267]; female pregnancy [GO:0007565]; insulin secretion [GO:0030073]; negative regulation of cell cycle [GO:0045786]; neuron projection development [GO:0031175]; neuropeptide signaling pathway [GO:0007218]; positive regulation of chemokine (C-C motif) ligand 5 production [GO:0071651]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of growth hormone secretion [GO:0060124]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; regulation of protein localization [GO:0032880] extracellular region [GO:0005576]; neuron projection [GO:0043005]; perikaryon [GO:0043204] neuropeptide hormone activity [GO:0005184]; peptide hormone receptor binding [GO:0051428]; pituitary adenylate cyclase activating polypeptide activity [GO:0016521]; signaling receptor binding [GO:0005102] 0.89857 -0.66484 AAAAWYRPAGR 0 0 11.7564 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P18583 SON_HUMAN Protein SON (Bax antagonist selected in saccharomyces 1) (BASS1) (Negative regulatory element-binding protein) (NRE-binding protein) (Protein DBP-5) (SON3) SON C21orf50 DBP5 KIAA1019 NREBP HSPC310 HSPC312 Homo sapiens (Human) "microtubule cytoskeleton organization [GO:0000226]; mitotic cytokinesis [GO:0000281]; mRNA processing [GO:0006397]; negative regulation of apoptotic process [GO:0043066]; regulation of cell cycle [GO:0051726]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]" nuclear speck [GO:0016607] DNA binding [GO:0003677]; RNA binding [GO:0003723] 0.91629 -0.8368 SFSISPVR 0 10.9873 8.62604 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9276 0 0 0 0 0 0 0 0 0 0 P18621 RL17_HUMAN Large ribosomal subunit protein uL22 (60S ribosomal protein L17) (60S ribosomal protein L23) (PD-1) RPL17 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; nucleus [GO:0005634] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.022371 1.5668 GLDVDSLVIEHIQVNK 0 9.0628 0 0 0 0 0 9.14865 9.33624 0 0 8.69554 0 0 0 0 0 0 9.00146 0 0 9.31034 0 0 0 0 0 P18669 PGAM1_HUMAN Phosphoglycerate mutase 1 (EC 5.4.2.11) (EC 5.4.2.4) (BPG-dependent PGAM 1) (Phosphoglycerate mutase isozyme B) (PGAM-B) PGAM1 PGAMA CDABP0006 Homo sapiens (Human) canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of glycolytic process [GO:0006110]; regulation of pentose-phosphate shunt [GO:0043456]; respiratory burst [GO:0045730] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; secretory granule lumen [GO:0034774] "2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; protein kinase binding [GO:0019901]" 0 22.499 ALPFWNEEIVPQIK 0 0 0 0 0 0 0 9.39253 0 0 0 0 0 0 0 0 0 11.9692 10.3067 10.505 10.5112 10.7221 10.1378 10.4717 11.7754 12.3141 10.588 P18754 RCC1_HUMAN Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1) RCC1 CHC1 Homo sapiens (Human) cell division [GO:0051301]; chromosome segregation [GO:0007059]; G1/S transition of mitotic cell cycle [GO:0000082]; mitotic nuclear membrane reassembly [GO:0007084]; mitotic spindle organization [GO:0007052]; regulation of mitotic nuclear division [GO:0007088]; spindle assembly [GO:0051225]; viral process [GO:0016032] chromatin [GO:0000785]; chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] chromatin binding [GO:0003682]; guanyl-nucleotide exchange factor activity [GO:0005085]; histone binding [GO:0042393]; nucleosomal DNA binding [GO:0031492]; nucleosome binding [GO:0031491]; protein heterodimerization activity [GO:0046982]; small GTPase binding [GO:0031267]; sulfate binding [GO:0043199] 0.88379 -0.26208 DTSVEGSEMVPGKVELQEK 0 0 0 0 0 0 0 0 10.2099 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P18825 ADA2C_HUMAN Alpha-2C adrenergic receptor (Alpha-2 adrenergic receptor subtype C4) (Alpha-2C adrenoreceptor) (Alpha-2C adrenoceptor) (Alpha-2CAR) ADRA2C ADRA2L2 ADRA2RL2 Homo sapiens (Human) activation of protein kinase B activity [GO:0032148]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adrenergic receptor signaling pathway [GO:0071875]; cell-cell signaling [GO:0007267]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of epinephrine secretion [GO:0032811]; negative regulation of norepinephrine secretion [GO:0010700]; platelet activation [GO:0030168]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron differentiation [GO:0045666]; receptor transactivation [GO:0035624]; regulation of smooth muscle contraction [GO:0006940]; regulation of vasoconstriction [GO:0019229] cytoplasm [GO:0005737]; endosome [GO:0005768]; plasma membrane [GO:0005886] alpha-2A adrenergic receptor binding [GO:0031694]; alpha2-adrenergic receptor activity [GO:0004938]; epinephrine binding [GO:0051379]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803] 0.955 -1.5792 ARSSVCRR 0 0 0 0 0 0 0 0 9.24949 0 9.21653 0 0 9.22226 0 8.87937 8.55013 8.95667 0 0 0 0 0 0 0 11.0049 7.59656 P18848 ATF4_HUMAN Cyclic AMP-dependent transcription factor ATF-4 (cAMP-dependent transcription factor ATF-4) (Activating transcription factor 4) (Cyclic AMP-responsive element-binding protein 2) (CREB-2) (cAMP-responsive element-binding protein 2) (Tax-responsive enhancer element-binding protein 67) (TaxREB67) ATF4 CREB2 TXREB Homo sapiens (Human) bone mineralization [GO:0030282]; cellular response to amino acid starvation [GO:0034198]; cellular response to glucose starvation [GO:0042149]; cellular response to leucine starvation [GO:1990253]; cellular response to oxidative stress [GO:0034599]; cellular response to oxygen-glucose deprivation [GO:0090650]; cellular response to UV [GO:0034644]; circadian regulation of gene expression [GO:0032922]; embryonic hemopoiesis [GO:0035162]; endoplasmic reticulum unfolded protein response [GO:0030968]; gamma-aminobutyric acid signaling pathway [GO:0007214]; gluconeogenesis [GO:0006094]; HRI-mediated signaling [GO:0140468]; integrated stress response signaling [GO:0140467]; intracellular calcium ion homeostasis [GO:0006874]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; L-asparagine metabolic process [GO:0070982]; lens fiber cell morphogenesis [GO:0070309]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of translational initiation in response to stress [GO:0032057]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of apoptotic process [GO:0043065]; positive regulation of biomineral tissue development [GO:0070169]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of sodium-dependent phosphate transport [GO:2000120]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0036091]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of DNA-templated transcription [GO:0006355]; regulation of osteoblast differentiation [GO:0045667]; regulation of synaptic plasticity [GO:0048167]; regulation of transcription by RNA polymerase II [GO:0006357]; response to endoplasmic reticulum stress [GO:0034976]; response to manganese-induced endoplasmic reticulum stress [GO:1990737]; response to nutrient levels [GO:0031667]; response to toxic substance [GO:0009636]; transcription by RNA polymerase II [GO:0006366] ATF1-ATF4 transcription factor complex [GO:1990590]; ATF4-CREB1 transcription factor complex [GO:1990589]; CHOP-ATF4 complex [GO:1990617]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; dendrite membrane [GO:0032590]; Lewy body core [GO:1990037]; microtubule organizing center [GO:0005815]; neuron projection [GO:0043005]; nuclear periphery [GO:0034399]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; RNA polymerase II transcription regulator complex [GO:0090575] "cAMP response element binding protein binding [GO:0008140]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; general transcription initiation factor binding [GO:0140296]; identical protein binding [GO:0042802]; leucine zipper domain binding [GO:0043522]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]" 0.85864 0.099649 DLIEEVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.492 0 0 0 0 P18850 ATF6A_HUMAN Cyclic AMP-dependent transcription factor ATF-6 alpha (cAMP-dependent transcription factor ATF-6 alpha) (Activating transcription factor 6 alpha) (ATF6-alpha) [Cleaved into: Processed cyclic AMP-dependent transcription factor ATF-6 alpha] ATF6 Homo sapiens (Human) ATF6-mediated unfolded protein response [GO:0036500]; endoplasmic reticulum unfolded protein response [GO:0030968]; ERAD pathway [GO:0036503]; eye development [GO:0001654]; positive regulation of apoptotic process [GO:0043065]; positive regulation of ATF6-mediated unfolded protein response [GO:1903893]; positive regulation of autophagy [GO:0010508]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; protein folding [GO:0006457]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; visual perception [GO:0007601] chromatin [GO:0000785]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]; ubiquitin protein ligase binding [GO:0031625]" 0.96953 -3.113 ESACQSRK 0 0 9.82747 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P18858 DNLI1_HUMAN DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1) LIG1 Homo sapiens (Human) "anatomical structure morphogenesis [GO:0009653]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation [GO:0006266]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; lagging strand elongation [GO:0006273]; mismatch repair [GO:0006298]; Okazaki fragment processing involved in mitotic DNA replication [GO:1903461]" intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA ligase (ATP) activity [GO:0003910]; DNA ligase activity [GO:0003909]; metal ion binding [GO:0046872] 0.96401 -2.2616 ETEPPPK 0 0 0 0 0 0 9.8743 0 0 10.3987 0 0 8.363 0 0 0 0 0 0 0 8.03276 0 0 0 0 0 0 P18887 XRCC1_HUMAN DNA repair protein XRCC1 (X-ray repair cross-complementing protein 1) XRCC1 Homo sapiens (Human) base-excision repair [GO:0006284]; cerebellum morphogenesis [GO:0021587]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; response to xenobiotic stimulus [GO:0009410]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; voluntary musculoskeletal movement [GO:0050882] "chromatin [GO:0000785]; chromosome, telomeric region [GO:0000781]; ERCC4-ERCC1 complex [GO:0070522]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of DNA damage [GO:0090734]" 3' overhang single-stranded DNA endodeoxyribonuclease activity [GO:1990599]; ADP-D-ribose modification-dependent protein binding [GO:0160002]; enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]; poly-ADP-D-ribose binding [GO:0072572] 0.91531 -0.79598 IVCSQPYSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5173 P19086 GNAZ_HUMAN Guanine nucleotide-binding protein G(z) subunit alpha (G(x) alpha chain) (Gz-alpha) GNAZ Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled serotonin receptor signaling pathway [GO:0098664]; negative regulation of insulin secretion [GO:0046676] cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; heterotrimeric G-protein complex [GO:0005834]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886] adenylate cyclase inhibitor activity [GO:0010855]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872] 0.84931 0.11595 IDFHNPDR 8.66274 8.67243 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P19099 C11B2_HUMAN "Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (Aldosterone-synthesizing enzyme) (CYPXIB2) (Corticosterone 18-monooxygenase, CYP11B2) (EC 1.14.15.5) (Cytochrome P-450Aldo) (Cytochrome P-450C18) (Steroid 11-beta-hydroxylase, CYP11B2) (EC 1.14.15.4) (Steroid 18-hydroxylase)" CYP11B2 Homo sapiens (Human) aldosterone biosynthetic process [GO:0032342]; C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to hormone stimulus [GO:0032870]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to potassium ion [GO:0035865]; cholesterol metabolic process [GO:0008203]; cortisol biosynthetic process [GO:0034651]; cortisol metabolic process [GO:0034650]; glucocorticoid biosynthetic process [GO:0006704]; mineralocorticoid biosynthetic process [GO:0006705]; potassium ion homeostasis [GO:0055075]; regulation of blood volume by renal aldosterone [GO:0002017]; renal water homeostasis [GO:0003091]; sodium ion homeostasis [GO:0055078]; sterol metabolic process [GO:0016125] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] corticosterone 18-monooxygenase activity [GO:0047783]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; steroid 11-beta-monooxygenase activity [GO:0004507]; steroid hydroxylase activity [GO:0008395] 0.83482 0.18757 HFLVETLTQEDIK 0 0 0 0 0 0 0 0 0 9.87891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P19105 ML12A_HUMAN "Myosin regulatory light chain 12A (Epididymis secretory protein Li 24) (HEL-S-24) (MLC-2B) (Myosin RLC) (Myosin regulatory light chain 2, nonsarcomeric) (Myosin regulatory light chain MRLC3)" MYL12A MLCB MRLC3 RLC Homo sapiens (Human) platelet aggregation [GO:0070527] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; myosin complex [GO:0016459] calcium ion binding [GO:0005509] 0 3.2959 GNFNYIEFTR 9.17585 9.00983 0 0 0 0 0 0 9.42905 9.12799 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P19113 DCHS_HUMAN Histidine decarboxylase (HDC) (EC 4.1.1.22) HDC Homo sapiens (Human) catecholamine biosynthetic process [GO:0042423]; histamine biosynthetic process [GO:0001694]; histidine catabolic process [GO:0006548]; histidine metabolic process [GO:0006547] cytoplasm [GO:0005737]; cytosol [GO:0005829] histidine decarboxylase activity [GO:0004398]; pyridoxal phosphate binding [GO:0030170] 0.91919 -0.89867 FPEDMMMLKK 0 0 0 0 0 0 0 8.45105 0 9.8746 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P19174 PLCG1_HUMAN "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (PLC-148) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-II) (PLC-II) (Phospholipase C-gamma-1) (PLC-gamma-1)" PLCG1 PLC1 Homo sapiens (Human) calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to epidermal growth factor stimulus [GO:0071364]; epidermal growth factor receptor signaling pathway [GO:0007173]; Fc-epsilon receptor signaling pathway [GO:0038095]; in utero embryonic development [GO:0001701]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; phosphatidylinositol metabolic process [GO:0046488]; phosphatidylinositol-mediated signaling [GO:0048015]; phospholipid catabolic process [GO:0009395]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; release of sequestered calcium ion into cytosol [GO:0051209]; T cell receptor signaling pathway [GO:0050852] cell projection [GO:0042995]; cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; Schaffer collateral - CA1 synapse [GO:0098685] calcium ion binding [GO:0005509]; calcium-dependent phospholipase C activity [GO:0050429]; glutamate receptor binding [GO:0035254]; neurotrophin TRKA receptor binding [GO:0005168]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipase C activity [GO:0004629]; protein kinase binding [GO:0019901]; receptor tyrosine kinase binding [GO:0030971] 0.91823 -0.88133 EIKEIRPGK 9.63216 9.80912 9.77487 0 0 9.44045 0 9.53904 9.31045 0 0 9.4452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P19320 VCAM1_HUMAN Vascular cell adhesion protein 1 (V-CAM 1) (VCAM-1) (INCAM-100) (CD antigen CD106) [Cleaved into: Soluble Vascular Cell Adhesion Molecule-1] VCAM1 Homo sapiens (Human) acute inflammatory response [GO:0002526]; aging [GO:0007568]; amine metabolic process [GO:0009308]; B cell differentiation [GO:0030183]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cardiac neuron differentiation [GO:0060945]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell adhesion in response to extracellular stimulus [GO:0140039]; cell-matrix adhesion [GO:0007160]; cellular response to amyloid-beta [GO:1904646]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chronic inflammatory response [GO:0002544]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; inflammatory response [GO:0006954]; innervation [GO:0060384]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte tethering or rolling [GO:0050901]; membrane to membrane docking [GO:0022614]; positive regulation of T cell proliferation [GO:0042102]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nutrient [GO:0007584]; response to zinc ion [GO:0010043] alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex [GO:0071065]; apical part of cell [GO:0045177]; cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; podosome [GO:0002102]; sarcolemma [GO:0042383] cell adhesion mediator activity [GO:0098631]; cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; primary amine oxidase activity [GO:0008131] 0.58576 0.46505 SLEMTFIPTIEDTGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.9767 0 0 0 P19338 NUCL_HUMAN Nucleolin (Protein C23) NCL Homo sapiens (Human) "angiogenesis [GO:0001525]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to leukemia inhibitory factor [GO:1990830]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of translation [GO:0017148]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901838]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]" cell cortex [GO:0005938]; chromosome [GO:0005694]; cornified envelope [GO:0001533]; cytoplasmic ribonucleoprotein granule [GO:0036464]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681] DNA topoisomerase binding [GO:0044547]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; mRNA 5'-UTR binding [GO:0048027]; PH domain binding [GO:0042731]; RNA binding [GO:0003723]; telomeric DNA binding [GO:0042162] 0 89.58 ALELTGLK 8.82703 10.0362 0 0 0 0 11.3685 11.6317 11.4439 10.8061 10.9774 10.2343 10.7302 10.1604 10.0863 12.4772 11.4573 10.5272 11.6384 11.8205 11.9392 10.6884 11.8063 11.7665 13.3016 13.37 13.3904 P19367 HXK1_HUMAN Hexokinase-1 (EC 2.7.1.1) (Brain form hexokinase) (Hexokinase type I) (HK I) (Hexokinase-A) HK1 Homo sapiens (Human) canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intracellular glucose homeostasis [GO:0001678]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of interleukin-1 beta production [GO:0032731] cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucosamine kinase activity [GO:0047931]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834] 0.21093 0.9069 ASGVEGADVVK 0 0 0 0 0 0 0 0 0 0 0 0 10.0787 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P19388 RPAB1_HUMAN "DNA-directed RNA polymerases I, II, and III subunit RPABC1 (RNA polymerases I, II, and III subunit ABC1) (DNA-directed RNA polymerase II 23 kDa polypeptide) (DNA-directed RNA polymerase II subunit E) (RPB5 homolog) (XAP4)" POLR2E Homo sapiens (Human) protein stabilization [GO:0050821]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383] "cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]; RPAP3/R2TP/prefoldin-like complex [GO:1990062]" DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899] 0.87751 -0.0051708 TIMQLCHDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.62145 0 P19429 TNNI3_HUMAN "Troponin I, cardiac muscle (Cardiac troponin I)" TNNI3 TNNC1 Homo sapiens (Human) cardiac muscle contraction [GO:0060048]; heart contraction [GO:0060047]; heart development [GO:0007507]; intracellular calcium ion homeostasis [GO:0006874]; negative regulation of ATP-dependent activity [GO:0032780]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of smooth muscle contraction [GO:0006940]; regulation of systemic arterial blood pressure by ischemic conditions [GO:0001980]; skeletal muscle contraction [GO:0003009]; vasculogenesis [GO:0001570]; ventricular cardiac muscle tissue morphogenesis [GO:0055010] cardiac myofibril [GO:0097512]; cardiac Troponin complex [GO:1990584]; cytosol [GO:0005829]; sarcomere [GO:0030017]; troponin complex [GO:0005861] actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium channel inhibitor activity [GO:0019855]; calcium-dependent protein binding [GO:0048306]; molecular function inhibitor activity [GO:0140678]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; troponin C binding [GO:0030172]; troponin T binding [GO:0031014] 0.89743 -0.58399 AYATEPHAKK 0 0 0 0 0 0 0 10.5455 0 10.9925 10.9879 10.9873 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P19438 TNR1A_HUMAN "Tumor necrosis factor receptor superfamily member 1A (Tumor necrosis factor receptor 1) (TNF-R1) (Tumor necrosis factor receptor type I) (TNF-RI) (TNFR-I) (p55) (p60) (CD antigen CD120a) [Cleaved into: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)]" TNFRSF1A TNFAR TNFR1 Homo sapiens (Human) aortic valve development [GO:0003176]; cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of extracellular matrix constituent secretion [GO:0003332]; negative regulation of inflammatory response [GO:0050728]; positive regulation of apoptotic process involved in morphogenesis [GO:1902339]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; prostaglandin metabolic process [GO:0006693]; protein localization to plasma membrane [GO:0072659]; pulmonary valve development [GO:0003177]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; transcription by RNA polymerase II [GO:0006366]; tumor necrosis factor-mediated signaling pathway [GO:0033209] cell surface [GO:0009986]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; tumor necrosis factor receptor superfamily complex [GO:0002947] tumor necrosis factor binding [GO:0043120]; tumor necrosis factor receptor activity [GO:0005031] 0.80227 0.23984 LYSIVCGK 0 0 0 0 0 0 0 0 0 0 0 9.95749 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P19447 ERCC3_HUMAN General transcription and DNA repair factor IIH helicase subunit XPB (TFIIH subunit XPB) (EC 3.6.4.12) (Basic transcription factor 2 89 kDa subunit) (BTF2 p89) (DNA excision repair protein ERCC-3) (DNA repair protein complementing XP-B cells) (TFIIH basal transcription factor complex 89 kDa subunit) (TFIIH 89 kDa subunit) (TFIIH p89) (Xeroderma pigmentosum group B-complementing protein) ERCC3 XPB XPBC Homo sapiens (Human) "apoptotic process [GO:0006915]; DNA repair [GO:0006281]; DNA topological change [GO:0006265]; embryonic organ development [GO:0048568]; hair cell differentiation [GO:0035315]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; positive regulation of apoptotic process [GO:0043065]; protein localization [GO:0008104]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]; response to UV [GO:0009411]; transcription by RNA polymerase II [GO:0006366]; transcription elongation by RNA polymerase II [GO:0006368]; transcription initiation at RNA polymerase II promoter [GO:0006367]; transcription-coupled nucleotide-excision repair [GO:0006283]; UV protection [GO:0009650]" nucleoplasm [GO:0005654]; nucleotide-excision repair factor 3 complex [GO:0000112]; nucleus [GO:0005634]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIH core complex [GO:0000439]; transcription factor TFIIH holo complex [GO:0005675]; transcription preinitiation complex [GO:0097550] 3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; promoter-specific chromatin binding [GO:1990841] 0.96284 -2.5231 QEAQRLGRVLR 0 0 0 0 0 0 0 0 0 0 0 0 11.5353 0 11.3173 0 0 10.0235 0 0 0 0 0 0 0 0 0 P19474 RO52_HUMAN E3 ubiquitin-protein ligase TRIM21 (EC 2.3.2.27) (52 kDa Ro protein) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (RING finger protein 81) (RING-type E3 ubiquitin transferase TRIM21) (Ro(SS-A)) (Sjoegren syndrome type A antigen) (SS-A) (Tripartite motif-containing protein 21) TRIM21 RNF81 RO52 SSA1 Homo sapiens (Human) cell cycle [GO:0007049]; cellular response to chemical stress [GO:0062197]; innate immune response [GO:0045087]; negative regulation of innate immune response [GO:0045824]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein deubiquitination [GO:0090086]; negative regulation of viral transcription [GO:0032897]; positive regulation of autophagy [GO:0010508]; positive regulation of cell cycle [GO:0045787]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein binding [GO:0032092]; positive regulation of viral entry into host cell [GO:0046598]; proteasomal protein catabolic process [GO:0010498]; protein autoubiquitination [GO:0051865]; protein destabilization [GO:0031648]; protein K48-linked ubiquitination [GO:0070936]; protein K6-linked ubiquitination [GO:0085020]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; pyroptosis [GO:0070269]; regulation of protein localization [GO:0032880]; regulation of type I interferon production [GO:0032479]; regulation of viral entry into host cell [GO:0046596]; response to type II interferon [GO:0034341]; suppression of viral release by host [GO:0044790] autophagosome [GO:0005776]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; ribonucleoprotein complex [GO:1990904] DNA binding [GO:0003677]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; transcription coactivator activity [GO:0003713]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.94673 -1.351 CAVHGER 0 0 0 0 9.44555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P19484 TFEB_HUMAN Transcription factor EB (Class E basic helix-loop-helix protein 35) (bHLHe35) TFEB BHLHE35 Homo sapiens (Human) adaptive immune response [GO:0002250]; antibacterial innate immune response [GO:0140367]; autophagy [GO:0006914]; cellular response to amino acid starvation [GO:0034198]; cellular response to starvation [GO:0009267]; embryonic placenta development [GO:0001892]; humoral immune response [GO:0006959]; lysosome localization [GO:0032418]; lysosome organization [GO:0007040]; positive regulation of autophagy [GO:0010508]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lysosomal membrane [GO:0005765]; nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; protein dimerization activity [GO:0046983]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]" 0.79141 0.24614 ELDDVIDNIMR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5574 0 0 0 0 0 0 P19525 E2AK2_HUMAN "Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 2) (eIF-2A protein kinase 2) (Interferon-inducible RNA-dependent protein kinase) (P1/eIF-2A protein kinase) (Protein kinase RNA-activated) (PKR) (Protein kinase R) (Tyrosine-protein kinase EIF2AK2) (EC 2.7.10.2) (p68 kinase)" EIF2AK2 PKR PRKR Homo sapiens (Human) antiviral innate immune response [GO:0140374]; cellular response to amino acid starvation [GO:0034198]; defense response to virus [GO:0051607]; endoplasmic reticulum unfolded protein response [GO:0030968]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of translation [GO:0017148]; negative regulation of viral genome replication [GO:0045071]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of hematopoietic progenitor cell differentiation [GO:1901532]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of NLRP3 inflammasome complex assembly [GO:1900225]; response to interferon-alpha [GO:0035455]; response to virus [GO:0009615]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840] ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; eukaryotic translation initiation factor 2alpha kinase activity [GO:0004694]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; molecular function activator activity [GO:0140677]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]; protein phosphatase regulator activity [GO:0019888]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; RNA binding [GO:0003723] 0.96929 -5.5543 ETKYTVDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3713 9.99181 0 0 0 0 0 11.2961 0 0 P19532 TFE3_HUMAN Transcription factor E3 (Class E basic helix-loop-helix protein 33) (bHLHe33) TFE3 BHLHE33 Homo sapiens (Human) adaptive immune response [GO:0002250]; humoral immune response [GO:0006959]; negative regulation of cold-induced thermogenesis [GO:0120163]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell adhesion [GO:0045785]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of osteoclast differentiation [GO:0045670]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein dimerization activity [GO:0046983]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]" 0.95982 -1.9435 WNKGTILKASVDYIR 0 0 0 0 0 0 11.0711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.7295 0 0 0 0 P19623 SPEE_HUMAN Spermidine synthase (SPDSY) (EC 2.5.1.16) (Putrescine aminopropyltransferase) SRM SPS1 SRML1 Homo sapiens (Human) cellular response to leukemia inhibitory factor [GO:1990830]; polyamine metabolic process [GO:0006595]; spermidine biosynthetic process [GO:0008295] cytosol [GO:0005829] identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; spermidine synthase activity [GO:0004766] 0.79982 0.24193 AAFVLPEFAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.36308 0 0 0 0 0 0 0 0 0 0 P19634 SL9A1_HUMAN "Sodium/hydrogen exchanger 1 (APNH) (Na(+)/H(+) antiporter, amiloride-sensitive) (Na(+)/H(+) exchanger 1) (NHE-1) (Solute carrier family 9 member 1)" SLC9A1 APNH1 NHE1 Homo sapiens (Human) cardiac muscle cell contraction [GO:0086003]; cardiac muscle cell differentiation [GO:0055007]; cell migration [GO:0016477]; cellular response to acidic pH [GO:0071468]; cellular response to antibiotic [GO:0071236]; cellular response to cold [GO:0070417]; cellular response to electrical stimulus [GO:0071257]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; intracellular sodium ion homeostasis [GO:0006883]; maintenance of cell polarity [GO:0030011]; monoatomic ion transport [GO:0006811]; negative regulation of apoptotic process [GO:0043066]; neuron death [GO:0070997]; positive regulation of action potential [GO:0045760]; positive regulation of apoptotic process [GO:0043065]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of calcium:sodium antiporter activity [GO:1903281]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell growth [GO:0030307]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of the force of heart contraction [GO:0098735]; positive regulation of transcription by RNA polymerase II [GO:0045944]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; proton transmembrane transport [GO:1902600]; regulation of cardiac muscle cell membrane potential [GO:0086036]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of focal adhesion assembly [GO:0051893]; regulation of intracellular pH [GO:0051453]; regulation of pH [GO:0006885]; regulation of sensory perception of pain [GO:0051930]; regulation of stress fiber assembly [GO:0051492]; regulation of the force of heart contraction by cardiac conduction [GO:0086092]; response to acidic pH [GO:0010447]; response to muscle stretch [GO:0035994]; sodium ion export across plasma membrane [GO:0036376]; sodium ion import across plasma membrane [GO:0098719]; stem cell differentiation [GO:0048863] apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cation-transporting ATPase complex [GO:0090533]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intercalated disc [GO:0014704]; lamellipodium [GO:0030027]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; T-tubule [GO:0030315] "calcium-dependent protein binding [GO:0048306]; calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; ion binding [GO:0043167]; molecular adaptor activity [GO:0060090]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; potassium:proton antiporter activity [GO:0015386]; protein phosphatase 2B binding [GO:0030346]; protein-macromolecule adaptor activity [GO:0030674]; sodium:proton antiporter activity [GO:0015385]; sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential [GO:0086040]" 0.95237 -1.3878 LDSPTMSRAR 0 0 9.74088 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P19793 RXRA_HUMAN Retinoic acid receptor RXR-alpha (Nuclear receptor subfamily 2 group B member 1) (Retinoid X receptor alpha) RXRA NR2B1 Homo sapiens (Human) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; hormone-mediated signaling pathway [GO:0009755]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of thyroid hormone mediated signaling pathway [GO:0002157]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transporter activity [GO:0032411]; positive regulation of vitamin D receptor signaling pathway [GO:0070564]; response to retinoic acid [GO:0032526]; retinoic acid receptor signaling pathway [GO:0048384] chromatin [GO:0000785]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; receptor complex [GO:0043235]; RNA polymerase II transcription regulator complex [GO:0090575]; transcription regulator complex [GO:0005667] "DNA binding domain binding [GO:0050692]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; ion binding [GO:0043167]; LBD domain binding [GO:0050693]; nuclear receptor activity [GO:0004879]; nuclear receptor binding [GO:0016922]; nuclear steroid receptor activity [GO:0003707]; nuclear vitamin D receptor binding [GO:0042809]; peptide binding [GO:0042277]; retinoic acid binding [GO:0001972]; retinoic acid-responsive element binding [GO:0044323]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]; transcription coregulator binding [GO:0001221]; zinc ion binding [GO:0008270]" 0.94742 -1.3565 CLAMGMKREAVQEER 0 0 0 0 0 0 0 0 0 0 9.49723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P19801 AOC1_HUMAN Amiloride-sensitive amine oxidase [copper-containing] (DAO) (Diamine oxidase) (EC 1.4.3.22) (Amiloride-binding protein 1) (Amine oxidase copper domain-containing protein 1) (Histaminase) (Kidney amine oxidase) (KAO) AOC1 ABP1 DAO1 Homo sapiens (Human) amine metabolic process [GO:0009308]; cellular response to azide [GO:0097185]; cellular response to copper ion [GO:0071280]; cellular response to copper ion starvation [GO:0035874]; cellular response to heparin [GO:0071504]; cellular response to histamine [GO:0071420]; putrescine metabolic process [GO:0009445]; response to antibiotic [GO:0046677] bicellular tight junction [GO:0005923]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; specific granule lumen [GO:0035580] "calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; diamine oxidase activity [GO:0052597]; heparin binding [GO:0008201]; histamine oxidase activity [GO:0052598]; methylputrescine oxidase activity [GO:0052599]; primary amine oxidase activity [GO:0008131]; propane-1,3-diamine oxidase activity [GO:0052600]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; quinone binding [GO:0048038]; zinc ion binding [GO:0008270]" 0.73058 0.33539 LVQPHGPR 0 0 0 0 0 0 0 0 0 9.56948 0 9.0367 0 0 0 0 0 9.97427 0 0 0 0 0 0 10.8865 0 0 P19823 ITIH2_HUMAN Inter-alpha-trypsin inhibitor heavy chain H2 (ITI heavy chain H2) (ITI-HC2) (Inter-alpha-inhibitor heavy chain 2) (Inter-alpha-trypsin inhibitor complex component II) (Serum-derived hyaluronan-associated protein) (SHAP) ITIH2 IGHEP2 Homo sapiens (Human) hyaluronan metabolic process [GO:0030212]; negative regulation of peptidase activity [GO:0010466] blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576] endopeptidase inhibitor activity [GO:0004866]; hyaluronic acid binding [GO:0005540]; serine-type endopeptidase inhibitor activity [GO:0004867] 0.064128 1.3058 AEDHFSVIDFNQNIRTWR 0 0 0 0 0 0 0 0 0 8.83857 8.80922 0 0 0 0 0 0 0 0 0 0 9.35405 0 0 0 0 0 P19827 ITIH1_HUMAN Inter-alpha-trypsin inhibitor heavy chain H1 (ITI heavy chain H1) (ITI-HC1) (Inter-alpha-inhibitor heavy chain 1) (Inter-alpha-trypsin inhibitor complex component III) (Serum-derived hyaluronan-associated protein) (SHAP) ITIH1 IGHEP1 Homo sapiens (Human) hyaluronan metabolic process [GO:0030212]; negative regulation of peptidase activity [GO:0010466] blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576] calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; hyaluronic acid binding [GO:0005540]; serine-type endopeptidase inhibitor activity [GO:0004867] 0.97002 -4.1556 IADNKQSSFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.3382 0 9.44018 0 10.5664 0 0 0 0 P19835 CEL_HUMAN Bile salt-activated lipase (BAL) (EC 3.1.1.13) (EC 3.1.1.3) (EC 3.1.1.6) (Bile salt-stimulated lipase) (BSSL) (Bucelipase) (Carboxyl ester lipase) (Cholesterol esterase) (Pancreatic lysophospholipase) (Sterol esterase) CEL BAL Homo sapiens (Human) ceramide catabolic process [GO:0046514]; intestinal cholesterol absorption [GO:0030299]; lipid metabolic process [GO:0006629]; pancreatic juice secretion [GO:0030157] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615] acetylesterase activity [GO:0008126]; catalytic activity [GO:0003824]; heparin binding [GO:0008201]; hydrolase activity [GO:0016787]; retinyl-palmitate esterase activity [GO:0050253]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806] 0.91591 -0.77154 AMIAYWTNFAK 0 0 0 0 0 0 0 0 0 0 0 0 10.6315 0 9.10392 0 0 0 9.56786 0 0 0 0 0 0 0 0 P19883 FST_HUMAN Follistatin (FS) (Activin-binding protein) FST Homo sapiens (Human) ameloblast differentiation [GO:0036305]; BMP signaling pathway [GO:0030509]; cell differentiation [GO:0030154]; female gonad development [GO:0008585]; gamete generation [GO:0007276]; hair follicle morphogenesis [GO:0031069]; hematopoietic progenitor cell differentiation [GO:0002244]; keratinocyte proliferation [GO:0043616]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis of dentin-containing tooth [GO:0042475]; pattern specification process [GO:0007389]; positive regulation of hair follicle development [GO:0051798]; regulation of BMP signaling pathway [GO:0030510]; response to organic cyclic compound [GO:0014070]; skeletal system development [GO:0001501] cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634] activin binding [GO:0048185]; activin receptor antagonist activity [GO:0038102]; heparan sulfate proteoglycan binding [GO:0043395] 0.78601 0.25526 SIGLAYEGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.47446 0 0 0 0 0 0 0 0 0 0 0 0 P19957 ELAF_HUMAN Elafin (Elastase-specific inhibitor) (ESI) (Peptidase inhibitor 3) (PI-3) (Protease inhibitor WAP3) (Skin-derived antileukoproteinase) (SKALP) (WAP four-disulfide core domain protein 14) PI3 WAP3 WFDC14 Homo sapiens (Human) antibacterial humoral response [GO:0019731]; copulation [GO:0007620]; innate immune response [GO:0045087]; negative regulation of peptidase activity [GO:0010466]; peptide cross-linking [GO:0018149] cornified envelope [GO:0001533]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576] endopeptidase inhibitor activity [GO:0004866]; serine-type endopeptidase inhibitor activity [GO:0004867]; structural constituent of skin epidermis [GO:0030280] 0.43547 0.65622 KCCEGSCGMACFVPQ 0 0 0 0 0 0 9.23292 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P19971 TYPH_HUMAN Thymidine phosphorylase (TP) (EC 2.4.2.4) (Gliostatin) (Platelet-derived endothelial cell growth factor) (PD-ECGF) (TdRPase) TYMP ECGF1 Homo sapiens (Human) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; dTMP catabolic process [GO:0046074]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]; regulation of gastric motility [GO:1905333]; regulation of myelination [GO:0031641]; regulation of transmission of nerve impulse [GO:0051969] cytosol [GO:0005829] "1,4-alpha-oligoglucan phosphorylase activity [GO:0004645]; growth factor activity [GO:0008083]; protein homodimerization activity [GO:0042803]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]" 0.96161 -2.6037 AREQEELLAPADGTVELVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0161 0 0 0 P20020 AT2B1_HUMAN Plasma membrane calcium-transporting ATPase 1 (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 1) (PMCA1) (Plasma membrane calcium pump isoform 1) ATP2B1 PMCA1 Homo sapiens (Human) aging [GO:0007568]; brain development [GO:0007420]; calcium ion export [GO:1901660]; calcium ion export across plasma membrane [GO:1990034]; cellular response to corticosterone stimulus [GO:0071386]; cellular response to vitamin D [GO:0071305]; monoatomic ion transmembrane transport [GO:0034220]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; neural retina development [GO:0003407]; positive regulation of bone mineralization [GO:0030501]; positive regulation of calcium ion transport [GO:0051928]; regulation of blood pressure [GO:0008217]; regulation of cardiac conduction [GO:1903779]; regulation of cellular response to insulin stimulus [GO:1900076]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of vascular associated smooth muscle contraction [GO:0003056]; response to cold [GO:0009409] apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cytoplasmic side of plasma membrane [GO:0009898]; dendritic spine membrane [GO:0032591]; extracellular exosome [GO:0070062]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuronal cell body membrane [GO:0032809]; nucleoplasm [GO:0005654]; photoreceptor ribbon synapse [GO:0098684]; plasma membrane [GO:0005886]; presynaptic active zone membrane [GO:0048787]; presynaptic membrane [GO:0042734]; synaptic vesicle membrane [GO:0030672] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; calcium ion transmembrane transporter activity [GO:0015085]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; P-type calcium transporter activity [GO:0005388]; PDZ domain binding [GO:0030165] 0.95334 -1.4971 EGGLPRHVGNK 0 0 0 0 16.6986 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P20023 CR2_HUMAN Complement receptor type 2 (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD antigen CD21) CR2 C3DR Homo sapiens (Human) "B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; immune response [GO:0006955]; negative regulation of complement activation, classical pathway [GO:0045959]; T cell mediated immunity [GO:0002456]" extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] complement binding [GO:0001848]; complement receptor activity [GO:0004875]; DNA binding [GO:0003677]; immunoglobulin receptor binding [GO:0034987]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618] 0.84869 0.11514 CNAQGTWEPSAPVCEK 0 9.92679 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P20042 IF2B_HUMAN Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF-2-beta) EIF2S2 EIF2B Homo sapiens (Human) formation of cytoplasmic translation initiation complex [GO:0001732]; formation of translation preinitiation complex [GO:0001731]; in utero embryonic development [GO:0001701]; male germ cell proliferation [GO:0002176]; male gonad development [GO:0008584]; translational initiation [GO:0006413] cytoplasm [GO:0005737]; cytosol [GO:0005829]; eukaryotic translation initiation factor 2 complex [GO:0005850]; synapse [GO:0045202] "metal ion binding [GO:0046872]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; translation factor activity, RNA binding [GO:0008135]; translation initiation factor activity [GO:0003743]; translation initiation factor binding [GO:0031369]" 0.92288 -1.0818 EKNPDMVAGEK 0 0 0 0 0 0 0 0 0 0 12.0639 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P20132 SDHL_HUMAN L-serine dehydratase/L-threonine deaminase (SDH) (EC 4.3.1.17) (L-serine deaminase) (L-threonine dehydratase) (TDH) (EC 4.3.1.19) SDS SDH Homo sapiens (Human) gluconeogenesis [GO:0006094]; isoleucine biosynthetic process [GO:0009097]; L-serine catabolic process [GO:0006565]; lipid metabolic process [GO:0006629]; pyruvate biosynthetic process [GO:0042866]; threonine catabolic process [GO:0006567] cytosol [GO:0005829]; mitochondrion [GO:0005739] L-serine ammonia-lyase activity [GO:0003941]; L-threonine ammonia-lyase activity [GO:0004794]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170] 0.96771 -3.6659 ITSVAKALGVKTVGAQALK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7844 P20138 CD33_HUMAN Myeloid cell surface antigen CD33 (Sialic acid-binding Ig-like lectin 3) (Siglec-3) (gp67) (CD antigen CD33) CD33 SIGLEC3 Homo sapiens (Human) cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; immune response-inhibiting signal transduction [GO:0002765]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of monocyte activation [GO:0150102]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of protein secretion [GO:0050714]; positive regulation of protein tyrosine phosphatase activity [GO:1903615]; signal transduction [GO:0007165] cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821] carbohydrate binding [GO:0030246]; protein phosphatase binding [GO:0019903]; sialic acid binding [GO:0033691]; signaling receptor activity [GO:0038023] 0.81974 0.2188 NSPVHGYWFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3343 0 0 0 0 0 P20142 PEPC_HUMAN Gastricsin (EC 3.4.23.3) (Pepsinogen C) PGC Homo sapiens (Human) digestion [GO:0007586]; positive regulation of antibacterial peptide production [GO:0002803]; proteolysis [GO:0006508] extracellular space [GO:0005615] aspartic-type endopeptidase activity [GO:0004190] 0.67724 0.39371 VGFATAA 8.12634 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.56704 0 0 0 9.3773 P20248 CCNA2_HUMAN Cyclin-A2 (Cyclin-A) (Cyclin A) CCNA2 CCN1 CCNA Homo sapiens (Human) animal organ regeneration [GO:0031100]; cell cycle G1/S phase transition [GO:0044843]; cell division [GO:0051301]; cellular response to cocaine [GO:0071314]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hypoxia [GO:0071456]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to leptin stimulus [GO:0044320]; cellular response to luteinizing hormone stimulus [GO:0071373]; cellular response to nitric oxide [GO:0071732]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cochlea development [GO:0090102]; DNA-templated transcription [GO:0006351]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle phase transition [GO:0044772]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of fibroblast proliferation [GO:0048146]; post-translational protein modification [GO:0043687]; Ras protein signal transduction [GO:0007265]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of DNA replication [GO:0006275]; response to glucagon [GO:0033762] cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; female pronucleus [GO:0001939]; male pronucleus [GO:0001940]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901] 0.96192 -2.5603 AALAVLK 0 0 0 0 0 0 0 9.96264 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P20273 CD22_HUMAN B-cell receptor CD22 (B-lymphocyte cell adhesion molecule) (BL-CAM) (Sialic acid-binding Ig-like lectin 2) (Siglec-2) (T-cell surface antigen Leu-14) (CD antigen CD22) CD22 SIGLEC2 Homo sapiens (Human) B cell activation [GO:0042113]; cell adhesion [GO:0007155]; negative regulation of B cell receptor signaling pathway [GO:0050859]; negative regulation of calcium-mediated signaling [GO:0050849]; negative regulation of immunoglobulin production [GO:0002638]; regulation of B cell proliferation [GO:0030888]; regulation of endocytosis [GO:0030100]; regulation of immune response [GO:0050776] cell surface [GO:0009986]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037] carbohydrate binding [GO:0030246]; CD4 receptor binding [GO:0042609]; IgM binding [GO:0001791]; protein phosphatase binding [GO:0019903]; sialic acid binding [GO:0033691]; signaling receptor binding [GO:0005102] 0.96321 -2.6556 EVQFFWEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.3415 9.79771 9.76719 9.77665 0 9.75662 0 P20290 BTF3_HUMAN Transcription factor BTF3 (Nascent polypeptide-associated complex subunit beta) (NAC-beta) (RNA polymerase B transcription factor 3) BTF3 NACB OK/SW-cl.8 Homo sapiens (Human) in utero embryonic development [GO:0001701]; negative regulation of protein localization to endoplasmic reticulum [GO:1905551]; protein transport [GO:0015031] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nascent polypeptide-associated complex [GO:0005854]; nucleus [GO:0005634]; polysomal ribosome [GO:0042788] RNA binding [GO:0003723] 0.92051 -1.1421 IGGKGTAR 0 0 0 0 0 0 0 0 0 0 0 0 9.24693 0 9.34283 0 9.28529 0 0 0 0 0 0 0 0 0 0 P20336 RAB3A_HUMAN Ras-related protein Rab-3A RAB3A Homo sapiens (Human) acrosomal vesicle exocytosis [GO:0060478]; axonogenesis [GO:0007409]; calcium-ion regulated exocytosis [GO:0017156]; constitutive secretory pathway [GO:0045054]; evoked neurotransmitter secretion [GO:0061670]; exocytosis [GO:0006887]; insulin secretion [GO:0030073]; lung development [GO:0030324]; lysosome localization [GO:0032418]; maintenance of presynaptic active zone structure [GO:0048790]; mitochondrion organization [GO:0007005]; neuromuscular synaptic transmission [GO:0007274]; plasma membrane repair [GO:0001778]; positive regulation of exocytosis [GO:0045921]; positive regulation of regulated secretory pathway [GO:1903307]; post-embryonic development [GO:0009791]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; regulated exocytosis [GO:0045055]; regulation of dopamine secretion [GO:0014059]; regulation of exocytosis [GO:0017157]; regulation of plasma membrane repair [GO:1905684]; regulation of presynaptic dense core granule exocytosis [GO:0099161]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic vesicle fusion to presynaptic active zone membrane [GO:0031630]; regulation of synaptic vesicle priming [GO:0010807]; respiratory system process [GO:0003016]; response to electrical stimulus [GO:0051602]; sensory perception of touch [GO:0050975]; synaptic vesicle clustering [GO:0097091]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle maturation [GO:0016188]; synaptic vesicle recycling [GO:0036465]; synaptic vesicle transport [GO:0048489]; vesicle docking involved in exocytosis [GO:0006904] acrosomal vesicle [GO:0001669]; axon [GO:0030424]; clathrin-sculpted acetylcholine transport vesicle membrane [GO:0060201]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; clathrin-sculpted glutamate transport vesicle membrane [GO:0060203]; clathrin-sculpted monoamine transport vesicle membrane [GO:0070083]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular vesicle [GO:1903561]; lysosome [GO:0005764]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; presynapse [GO:0098793]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; secretory granule membrane [GO:0030667]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195] ATPase activator activity [GO:0001671]; ATPase binding [GO:0051117]; GDP-dissociation inhibitor binding [GO:0051021]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; myosin V binding [GO:0031489]; protein-macromolecule adaptor activity [GO:0030674] 0.95984 -1.9471 CDMEDERVVSSER 0 0 0 0 0 8.98219 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P20339 RAB5A_HUMAN Ras-related protein Rab-5A (EC 3.6.5.2) RAB5A RAB5 Homo sapiens (Human) amyloid-beta clearance by transcytosis [GO:0150093]; early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; modulation by host of viral process [GO:0044788]; phagocytosis [GO:0006909]; positive regulation of exocytosis [GO:0045921]; receptor internalization involved in canonical Wnt signaling pathway [GO:2000286]; regulation of autophagosome assembly [GO:2000785]; regulation of endosome size [GO:0051036]; regulation of filopodium assembly [GO:0051489]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of synaptic vesicle exocytosis [GO:2000300]; synaptic vesicle recycling [GO:0036465] actin cytoskeleton [GO:0015629]; axon [GO:0030424]; axon terminus [GO:0043679]; clathrin-coated endocytic vesicle membrane [GO:0030669]; cytoplasm [GO:0005737]; cytoplasmic side of early endosome membrane [GO:0098559]; cytosol [GO:0005829]; dendrite [GO:0030425]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; early phagosome [GO:0032009]; endomembrane system [GO:0012505]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; phagocytic vesicle [GO:0045335]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; postsynaptic early endosome [GO:0098842]; ruffle [GO:0001726]; somatodendritic compartment [GO:0036477]; synaptic vesicle [GO:0008021]; terminal bouton [GO:0043195] G protein activity [GO:0003925]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.90991 -0.74467 ASRGATRPNGPNTGNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3795 0 0 0 0 0 P20366 TKN1_HUMAN Protachykinin-1 (PPT) [Cleaved into: Substance P; Neurokinin A (NKA) (Neuromedin L) (Substance K); Neuropeptide K (NPK); Neuropeptide gamma; C-terminal-flanking peptide] TAC1 NKA NKNA TAC2 Homo sapiens (Human) antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell-cell signaling [GO:0007267]; cellular response to nerve growth factor stimulus [GO:1990090]; chemical synaptic transmission [GO:0007268]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of abiotic stimulus [GO:0009582]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; insemination [GO:0007320]; killing of cells of another organism [GO:0031640]; negative regulation of systemic arterial blood pressure [GO:0003085]; neuropeptide signaling pathway [GO:0007218]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of flagellated sperm motility [GO:1902093]; positive regulation of sensory perception of pain [GO:1904058]; regulation of sensory perception of pain [GO:0051930]; response to pain [GO:0048265]; response to yeast [GO:0001878]; sensory perception of pain [GO:0019233]; tachykinin receptor signaling pathway [GO:0007217] axon [GO:0030424]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; synapse [GO:0045202] neuromedin K receptor binding [GO:0031836]; receptor ligand activity [GO:0048018]; substance K receptor binding [GO:0031837]; substance P receptor binding [GO:0031835] 0.94395 -1.3368 RHKTDSFVGLMGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.12975 P20393 NR1D1_HUMAN Nuclear receptor subfamily 1 group D member 1 (Rev-erbA-alpha) (V-erbA-related protein 1) (EAR-1) NR1D1 EAR1 HREV THRAL Homo sapiens (Human) cell differentiation [GO:0030154]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; circadian regulation of gene expression [GO:0032922]; circadian temperature homeostasis [GO:0060086]; glycogen biosynthetic process [GO:0005978]; hormone-mediated signaling pathway [GO:0009755]; intracellular glucose homeostasis [GO:0001678]; negative regulation of astrocyte activation [GO:0061889]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of neuroinflammatory response [GO:0150079]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of bile acid biosynthetic process [GO:0070859]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasomal protein catabolic process [GO:0010498]; protein destabilization [GO:0031648]; regulation of circadian rhythm [GO:0042752]; regulation of circadian sleep/wake cycle [GO:0042749]; regulation of fat cell differentiation [GO:0045598]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; regulation of lipid metabolic process [GO:0019216]; regulation of type B pancreatic cell proliferation [GO:0061469]; response to leptin [GO:0044321] chromatin [GO:0000785]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; E-box binding [GO:0070888]; heme binding [GO:0020037]; nuclear receptor activity [GO:0004879]; nuclear steroid receptor activity [GO:0003707]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]; transcription corepressor binding [GO:0001222]; zinc ion binding [GO:0008270]" 0.83617 0.19315 APANSPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.8439 0 0 0 0 0 0 0 0 0 0 0 P20585 MSH3_HUMAN DNA mismatch repair protein Msh3 (hMSH3) (Divergent upstream protein) (DUP) (Mismatch repair protein 1) (MRP1) MSH3 DUC1 DUG Homo sapiens (Human) DNA repair [GO:0006281]; maintenance of DNA repeat elements [GO:0043570]; mismatch repair [GO:0006298]; mitotic recombination [GO:0006312]; negative regulation of DNA recombination [GO:0045910]; positive regulation of helicase activity [GO:0051096]; somatic recombination of immunoglobulin gene segments [GO:0016447] membrane [GO:0016020]; MutSbeta complex [GO:0032302]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP-dependent DNA damage sensor activity [GO:0140664]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; mismatched DNA binding [GO:0030983] 0.9526 -1.457 FHSPFIVENYR 0 0 0 0 0 0 8.98556 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.79173 0 9.19419 0 P20591 MX1_HUMAN "Interferon-induced GTP-binding protein Mx1 (Interferon-induced protein p78) (IFI-78K) (Interferon-regulated resistance GTP-binding protein MxA) (Myxoma resistance protein 1) (Myxovirus resistance protein 1) [Cleaved into: Interferon-induced GTP-binding protein Mx1, N-terminally processed]" MX1 Homo sapiens (Human) antiviral innate immune response [GO:0140374]; apoptotic process [GO:0006915]; defense response [GO:0006952]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; interleukin-27-mediated signaling pathway [GO:0070106]; negative regulation of viral genome replication [GO:0045071]; response to type I interferon [GO:0034340]; response to virus [GO:0009615]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; microtubule [GO:0005874]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017] 0.88491 -0.3334 ELEEEKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.4028 0 0 0 0 0 0 0 0 0 0 0 P20592 MX2_HUMAN Interferon-induced GTP-binding protein Mx2 (Interferon-regulated resistance GTP-binding protein MxB) (Myxovirus resistance protein 2) (p78-related protein) MX2 Homo sapiens (Human) defense response [GO:0006952]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; mRNA transport [GO:0051028]; protein transport [GO:0015031]; regulation of cell cycle [GO:0051726]; regulation of nucleocytoplasmic transport [GO:0046822]; response to interferon-alpha [GO:0035455]; response to virus [GO:0009615] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; microtubule [GO:0005874]; nuclear pore [GO:0005643]; nucleus [GO:0005634] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; microtubule binding [GO:0008017] 0.91338 -0.75471 AENMIQLQFR 10.822 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.6786 11.1714 10.5008 P20594 ANPRB_HUMAN Atrial natriuretic peptide receptor 2 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type B) (ANP-B) (ANPR-B) (NPR-B) (Guanylate cyclase B) (GC-B) NPR2 ANPRB Homo sapiens (Human) activation of meiosis involved in egg activation [GO:0060466]; axonogenesis involved in innervation [GO:0060385]; blood vessel remodeling [GO:0001974]; c-di-GMP signaling [GO:0061939]; cellular response to cGMP [GO:0071321]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to peptide [GO:1901653]; cGMP biosynthetic process [GO:0006182]; cGMP-mediated signaling [GO:0019934]; chemical synaptic transmission [GO:0007268]; chondrocyte differentiation [GO:0002062]; chondrocyte proliferation [GO:0035988]; chromosome organization [GO:0051276]; collateral sprouting [GO:0048668]; cumulus cell differentiation [GO:0001549]; digestive tract morphogenesis [GO:0048546]; endochondral ossification [GO:0001958]; epidermal growth factor receptor signaling pathway [GO:0007173]; execution phase of apoptosis [GO:0097194]; female genitalia development [GO:0030540]; gastric emptying [GO:0035483]; genitalia morphogenesis [GO:0035112]; growth plate cartilage development [GO:0003417]; limb morphogenesis [GO:0035108]; lymph vessel development [GO:0001945]; MAPK cascade [GO:0000165]; meiotic cell cycle process involved in oocyte maturation [GO:1903537]; multicellular organism growth [GO:0035264]; negative regulation of meiotic cell cycle [GO:0051447]; negative regulation of oocyte maturation [GO:1900194]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of cGMP-mediated signaling [GO:0010753]; post-anal tail morphogenesis [GO:0036342]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of blood pressure [GO:0008217]; response to fibroblast growth factor [GO:0071774]; response to luteinizing hormone [GO:0034699]; response to salt [GO:1902074]; sensory perception of sound [GO:0007605]; smooth muscle tissue development [GO:0048745]; spermatogenesis [GO:0007283]; startle response [GO:0001964]; vacuole organization [GO:0007033]; vascular wound healing [GO:0061042]; vasculogenesis [GO:0001570]; vestibulocochlear nerve maturation [GO:0021647]; white fat cell differentiation [GO:0050872] cilium [GO:0005929]; cytoplasm [GO:0005737]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202] ATP binding [GO:0005524]; GTP binding [GO:0005525]; guanylate cyclase activity [GO:0004383]; hormone binding [GO:0042562]; identical protein binding [GO:0042802]; natriuretic peptide receptor activity [GO:0016941]; peptide hormone binding [GO:0017046]; protein kinase activity [GO:0004672] 0.46403 0.63325 ITDYGLASFR 0 0 0 0 0 0 10.6038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1525 0 P20618 PSB1_HUMAN Proteasome subunit beta type-1 (Macropain subunit C5) (Multicatalytic endopeptidase complex subunit C5) (Proteasome component C5) (Proteasome gamma chain) PSMB1 PSC5 Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] "cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]" 0.38488 0.71596 DVFISAAER 0 0 0 0 0 0 0 0 0 0 0 0 11.9286 0 0 0 0 0 0 0 0 0 0 9.19069 0 0 0 P20645 MPRD_HUMAN Cation-dependent mannose-6-phosphate receptor (CD Man-6-P receptor) (CD-MPR) (46 kDa mannose 6-phosphate receptor) (MPR 46) M6PR MPR46 MPRD Homo sapiens (Human) endosome to lysosome transport [GO:0008333]; lysosomal transport [GO:0007041]; protein targeting to lysosome [GO:0006622]; receptor-mediated endocytosis [GO:0006898]; secretion of lysosomal enzymes [GO:0033299] clathrin-coated endocytic vesicle membrane [GO:0030669]; endosome [GO:0005768]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588]; transport vesicle [GO:0030133] protein domain specific binding [GO:0019904]; retromer complex binding [GO:1905394]; transmembrane signaling receptor activity [GO:0004888] 0.88498 -0.37152 EQRRAVVMISCNR 9.83493 0 0 0 0 0 0 0 11.2127 0 0 0 0 0 0 0 0 0 0 0 0 9.96026 0 9.78067 0 0 0 P20648 ATP4A_HUMAN Potassium-transporting ATPase alpha chain 1 (EC 7.2.2.19) (Gastric H(+)/K(+) ATPase subunit alpha) (Proton pump) ATP4A Homo sapiens (Human) intracellular potassium ion homeostasis [GO:0030007]; intracellular sodium ion homeostasis [GO:0006883]; monoatomic ion transmembrane transport [GO:0034220]; pH reduction [GO:0045851]; potassium ion import across plasma membrane [GO:1990573]; proton transmembrane transport [GO:1902600]; regulation of proton transport [GO:0010155]; response to xenobiotic stimulus [GO:0009410]; sodium ion export across plasma membrane [GO:0036376] apical plasma membrane [GO:0016324]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; magnesium ion binding [GO:0000287]; P-type potassium:proton transporter activity [GO:0008900]; P-type sodium:potassium-exchanging transporter activity [GO:0005391]; potassium ion binding [GO:0030955] 0.92064 -0.92016 AGGGGGK 0 10.5439 0 11.5027 0 0 9.86437 0 0 0 8.0735 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.64972 P20700 LMNB1_HUMAN Lamin-B1 LMNB1 LMN2 LMNB Homo sapiens (Human) heterochromatin formation [GO:0031507]; nuclear envelope organization [GO:0006998]; nuclear migration [GO:0007097]; nuclear pore localization [GO:0051664]; protein localization to nuclear envelope [GO:0090435] lamin filament [GO:0005638]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear inner membrane [GO:0005637]; nuclear lamina [GO:0005652]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] phospholipase binding [GO:0043274]; sequence-specific double-stranded DNA binding [GO:1990837]; structural constituent of cytoskeleton [GO:0005200]; structural molecule activity [GO:0005198] 0.84145 0.18328 AGGPTTPLSPTR 0 0 0 0 0 0 9.32454 9.4488 0 0 0 0 0 10.132 0 0 0 0 0 0 0 0 9.312 11.3759 0 0 0 P20702 ITAX_HUMAN "Integrin alpha-X (CD11 antigen-like family member C) (Leu M5) (Leukocyte adhesion glycoprotein p150,95 alpha chain) (Leukocyte adhesion receptor p150,95) (CD antigen CD11c)" ITGAX CD11C Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; defense response to virus [GO:0051607]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial tube morphogenesis [GO:1905956]; positive regulation of gene expression [GO:0010628]; positive regulation of myelination [GO:0031643] cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; ficolin-1-rich granule membrane [GO:0101003]; integrin alphaX-beta2 complex [GO:0034689]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; tertiary granule membrane [GO:0070821] integrin binding [GO:0005178]; metal ion binding [GO:0046872]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor activity [GO:0038023] 0.94082 -1.3312 DIQNQLKEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.263 0 0 P20749 BCL3_HUMAN B-cell lymphoma 3 protein (BCL-3) (Proto-oncogene BCL3) BCL3 BCL4 D19S37 Homo sapiens (Human) "antimicrobial humoral response [GO:0019730]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; DNA damage response [GO:0006974]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; extracellular matrix organization [GO:0030198]; follicular dendritic cell differentiation [GO:0002268]; germinal center formation [GO:0002467]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; marginal zone B cell differentiation [GO:0002315]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of T cell apoptotic process [GO:0070233]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of type II interferon production [GO:0032729]; protein import into nucleus [GO:0006606]; regulation of apoptotic process [GO:0042981]; regulation of DNA binding [GO:0051101]; regulation of NIK/NF-kappaB signaling [GO:1901222]; response to UV-C [GO:0010225]; response to virus [GO:0009615]; spleen development [GO:0048536]; T cell apoptotic process [GO:0070231]; T-helper 1 type immune response [GO:0042088]; T-helper 2 cell differentiation [GO:0045064]" Bcl3-Bcl10 complex [GO:0032996]; Bcl3/NF-kappaB2 complex [GO:0033257]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] DNA-binding transcription factor binding [GO:0140297]; histone deacetylase binding [GO:0042826]; protein-macromolecule adaptor activity [GO:0030674]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714] 0.91454 -0.80338 CPAGAMDEGPVDLRTRPK 0 0 0 0 0 0 9.5315 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P20783 NTF3_HUMAN Neurotrophin-3 (NT-3) (HDNF) (Nerve growth factor 2) (NGF-2) (Neurotrophic factor) NTF3 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; activation of protein kinase B activity [GO:0032148]; cell-cell signaling [GO:0007267]; induction of positive chemotaxis [GO:0050930]; memory [GO:0007613]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; nerve development [GO:0021675]; nerve growth factor signaling pathway [GO:0038180]; nervous system development [GO:0007399]; neuron projection morphogenesis [GO:0048812]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor internalization [GO:0002092]; regulation of apoptotic process [GO:0042981]; regulation of neuron differentiation [GO:0045664]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] extracellular region [GO:0005576]; synaptic vesicle [GO:0008021] chemoattractant activity [GO:0042056]; growth factor activity [GO:0008083]; nerve growth factor receptor binding [GO:0005163]; signaling receptor binding [GO:0005102] 0.96688 -2.8407 GIDDKHWNSQCK 0 0 11.1709 0 0 0 10.6916 0 0 0 10.9646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5065 P20794 MAK_HUMAN Serine/threonine-protein kinase MAK (EC 2.7.11.1) (Male germ cell-associated kinase) MAK Homo sapiens (Human) cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; intracellular signal transduction [GO:0035556]; intraciliary transport [GO:0042073]; negative regulation of non-motile cilium assembly [GO:1902856]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; spermatogenesis [GO:0007283] axoneme [GO:0005930]; centrosome [GO:0005813]; cilium [GO:0005929]; cytoplasm [GO:0005737]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; motile cilium [GO:0031514]; nucleus [GO:0005634]; photoreceptor connecting cilium [GO:0032391]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713] 0.92106 -1.1392 ICQVLGTPK 0 0 0 0 0 0 0 0 0 9.72398 10.8131 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P20807 CAN3_HUMAN Calpain-3 (EC 3.4.22.54) (Calcium-activated neutral proteinase 3) (CANP 3) (Calpain L3) (Calpain p94) (Muscle-specific calcium-activated neutral protease 3) (New calpain 1) (nCL-1) CAPN3 CANP3 CANPL3 NCL1 Homo sapiens (Human) apoptotic process [GO:0006915]; calcium-dependent self proteolysis [GO:1990092]; cellular response to calcium ion [GO:0071277]; cellular response to salt stress [GO:0071472]; G1 to G0 transition involved in cell differentiation [GO:0070315]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; muscle structure development [GO:0061061]; myofibril assembly [GO:0030239]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of protein sumoylation [GO:0033234]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of proteolysis [GO:0045862]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of satellite cell activation involved in skeletal muscle regeneration [GO:0014718]; protein catabolic process [GO:0030163]; protein destabilization [GO:0031648]; protein localization to membrane [GO:0072657]; protein-containing complex assembly [GO:0065003]; proteolysis [GO:0006508]; regulation of catalytic activity [GO:0050790]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of myoblast differentiation [GO:0045661]; response to calcium ion [GO:0051592]; response to muscle activity [GO:0014850]; sarcomere organization [GO:0045214]; self proteolysis [GO:0097264] cytoplasm [GO:0005737]; cytosol [GO:0005829]; myofibril [GO:0030016]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; T-tubule [GO:0030315]; Z disc [GO:0030018] calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; catalytic activity [GO:0003824]; cysteine-type peptidase activity [GO:0008234]; identical protein binding [GO:0042802]; ligase regulator activity [GO:0055103]; molecular adaptor activity [GO:0060090]; peptidase activity [GO:0008233]; sodium ion binding [GO:0031402]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432] 0.041304 1.4951 MACGLVR 0 0 0 0 0 0 0 0 0 0 14.2956 0 0 0 0 0 13.5282 0 8.56491 0 0 0 0 0 0 0 11.0148 P20813 CP2B6_HUMAN "Cytochrome P450 2B6 (EC 1.14.13.-) (1,4-cineole 2-exo-monooxygenase) (CYPIIB6) (Cytochrome P450 IIB1)" CYP2B6 Homo sapiens (Human) cellular ketone metabolic process [GO:0042180]; epoxygenase P450 pathway [GO:0019373]; steroid metabolic process [GO:0008202]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805] cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231] "anandamide 11,12 epoxidase activity [GO:0062188]; anandamide 14,15 epoxidase activity [GO:0062189]; anandamide 8,9 epoxidase activity [GO:0062187]; arachidonic acid epoxygenase activity [GO:0008392]; estrogen 2-hydroxylase activity [GO:0101021]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; testosterone 16-alpha-hydroxylase activity [GO:0008390]; testosterone 16-beta-hydroxylase activity [GO:0062184]" 0.92427 -1.0056 AEAFSGR 9.10847 0 0 0 0 8.27039 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P20839 IMDH1_HUMAN Inosine-5'-monophosphate dehydrogenase 1 (IMP dehydrogenase 1) (IMPD 1) (IMPDH 1) (EC 1.1.1.205) (IMPDH-I) IMPDH1 IMPD1 Homo sapiens (Human) GMP biosynthetic process [GO:0006177]; GTP biosynthetic process [GO:0006183] azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774] DNA binding [GO:0003677]; identical protein binding [GO:0042802]; IMP dehydrogenase activity [GO:0003938]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; nucleotide binding [GO:0000166]; RNA binding [GO:0003723] 0.83506 0.18676 DSQKQLLCGAAVGTREDDK 0 11.2164 0 0 0 0 0 9.52597 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P20849 CO9A1_HUMAN Collagen alpha-1(IX) chain COL9A1 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; extracellular matrix organization [GO:0030198] collagen type IX trimer [GO:0005594]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] carbohydrate binding [GO:0030246]; extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803] 0.50726 0.60797 GEQGASGEEGEAGER 0 0 0 0 0 0 0 0 8.85106 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P20908 CO5A1_HUMAN Collagen alpha-1(V) chain COL5A1 Homo sapiens (Human) "blood vessel development [GO:0001568]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; collagen biosynthetic process [GO:0032964]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye morphogenesis [GO:0048592]; heart morphogenesis [GO:0003007]; integrin biosynthetic process [GO:0045112]; negative regulation of endodermal cell differentiation [GO:1903225]; regulation of cellular component organization [GO:0051128]; skin development [GO:0043588]; supramolecular fiber organization [GO:0097435]; tendon development [GO:0035989]; wound healing, spreading of epidermal cells [GO:0035313]" basement membrane [GO:0005604]; collagen type V trimer [GO:0005588]; collagen type XI trimer [GO:0005592]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; platelet-derived growth factor binding [GO:0048407]; proteoglycan binding [GO:0043394] 0.96841 -3.6352 EGPPGEK 0 0 0 0 0 0 0 11.1503 0 0 0 0 0 0 0 0 0 11.5496 8.01369 0 0 0 0 0 0 0 0 P20916 MAG_HUMAN Myelin-associated glycoprotein (Siglec-4a) MAG GMA Homo sapiens (Human) axon regeneration [GO:0031103]; cell adhesion [GO:0007155]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cellular response to mechanical stimulus [GO:0071260]; central nervous system myelin formation [GO:0032289]; negative regulation of axon extension [GO:0030517]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of neuron projection development [GO:0010977]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of myelination [GO:0031643]; substantia nigra development [GO:0021762]; transmission of nerve impulse [GO:0019226] compact myelin [GO:0043218]; cytoplasm [GO:0005737]; membrane raft [GO:0045121]; mesaxon [GO:0097453]; myelin sheath [GO:0043209]; myelin sheath adaxonal region [GO:0035749]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; Schmidt-Lanterman incisure [GO:0043220] carbohydrate binding [GO:0030246]; ganglioside GT1b binding [GO:1905576]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; sialic acid binding [GO:0033691]; signaling receptor binding [GO:0005102] 0.91609 -0.76987 ISGAPEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.8334 0 0 0 0 0 0 0 0 0 0 0 0 P20929 NEBU_HUMAN Nebulin NEB Homo sapiens (Human) cardiac muscle thin filament assembly [GO:0071691]; muscle organ development [GO:0007517]; regulation of actin filament length [GO:0030832]; somatic muscle development [GO:0007525] actin cytoskeleton [GO:0015629]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; Z disc [GO:0030018] actin filament binding [GO:0051015]; structural constituent of muscle [GO:0008307] 0.9693 -31.054 AARQAASDVQYKK 11.3728 0 9.27009 0 0 0 9.57599 9.57886 11.1849 10.029 9.7539 10.8621 11.3025 9.13579 10.0786 10.673 12.6471 10.9268 10.1011 11.5243 9.82501 11.3651 10.8195 0 10.4485 10.1003 10.5558 P20930 FILA_HUMAN Filaggrin FLG Homo sapiens (Human) establishment of skin barrier [GO:0061436]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149] collagen-containing extracellular matrix [GO:0062023]; cornified envelope [GO:0001533]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; keratohyalin granule [GO:0036457]; nucleus [GO:0005634] calcium ion binding [GO:0005509]; structural constituent of skin epidermis [GO:0030280]; transition metal ion binding [GO:0046914] 0.96906 -6.769 ESARGQSGESSGR 0 0 0 0 0 0 0 0 0 10.9884 9.05544 0 8.45553 0 0 0 0 0 0 0 0 0 8.8254 0 0 0 9.59218 P20936 RASA1_HUMAN Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP) RASA1 GAP RASA Homo sapiens (Human) blood vessel morphogenesis [GO:0048514]; ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; mitotic cytokinesis [GO:0000281]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of neuron apoptotic process [GO:0043524]; regulation of actin filament polymerization [GO:0030833]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of RNA metabolic process [GO:0051252]; signal transduction [GO:0007165]; vasculogenesis [GO:0001570] cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ruffle [GO:0001726] GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; GTPase binding [GO:0051020]; phosphotyrosine residue binding [GO:0001784]; potassium channel inhibitor activity [GO:0019870]; signaling receptor binding [GO:0005102] 0.95975 -1.9737 GLQAFCNLR 0 0 0 0 0 0 0 0 0 0 0 8.92419 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.59335 P20941 PHOS_HUMAN Phosducin (PHD) (33 kDa phototransducing protein) (Protein MEKA) PDC Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; phototransduction [GO:0007602]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; visual perception [GO:0007601] cytosol [GO:0005829]; nucleus [GO:0005634]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750] phospholipase inhibitor activity [GO:0004859] 0.92599 -0.96399 EILRQMSSPQSR 9.04502 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P20962 PTMS_HUMAN Parathymosin PTMS Homo sapiens (Human) DNA replication [GO:0006260]; immune system process [GO:0002376]; negative regulation of apoptotic process [GO:0043066]; positive regulation of transcription by RNA polymerase II [GO:0045944] nucleus [GO:0005634] histone binding [GO:0042393] 0 4.3791 SVEAAAELSAK 0 0 0 0 0 0 0 0 0 0 0 0 9.30104 0 0 0 0 0 10.3853 0 9.50307 9.87975 9.73515 0 0 0 0 P21128 ENDOU_HUMAN Uridylate-specific endoribonuclease (EC 4.6.1.-) (Placental protein 11) (PP11) (Protein endoU) ENDOU Homo sapiens (Human) female pregnancy [GO:0007565]; immune response [GO:0006955]; proteolysis [GO:0006508] cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] growth factor activity [GO:0008083]; lyase activity [GO:0016829]; manganese ion binding [GO:0030145]; polysaccharide binding [GO:0030247]; RNA binding [GO:0003723]; RNA endonuclease activity [GO:0004521]; scavenger receptor activity [GO:0005044]; serine-type peptidase activity [GO:0008236] 0.87255 0.05052 VTGFHNWIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.95762 0 0 0 0 0 P21217 FUT3_HUMAN 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 (EC 2.4.1.65) (4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase) (EC 2.4.1.152) (Alpha-3-fucosyltransferase FUT3) (EC 2.4.1.-) (Blood group Lewis alpha-4-fucosyltransferase) (Lewis FT) (Fucosyltransferase 3) (Fucosyltransferase III) (FucT-III) FUT3 FT3B LE Homo sapiens (Human) cell-cell recognition [GO:0009988]; ceramide metabolic process [GO:0006672]; fucosylation [GO:0036065]; macromolecule glycosylation [GO:0043413]; oligosaccharide biosynthetic process [GO:0009312]; oligosaccharide metabolic process [GO:0009311]; positive regulation of cell-cell adhesion [GO:0022409]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127] extracellular exosome [GO:0070062]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; membrane [GO:0016020] 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity [GO:0017060]; 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity [GO:0017083]; alpha-(1->3)-fucosyltransferase activity [GO:0046920]; fucosyltransferase activity [GO:0008417] 0.90213 -0.70283 ETLRPRSFSWALDFCK 0 0 0 0 10.0083 0 0 0 0 0 0 0 0 0 0 0 9.96867 0 0 0 0 0 0 0 0 0 9.14718 P21266 GSTM3_HUMAN Glutathione S-transferase Mu 3 (EC 2.5.1.18) (GST class-mu 3) (GSTM3-3) (hGSTM3-3) GSTM3 GST5 Homo sapiens (Human) cellular detoxification of nitrogen compound [GO:0070458]; establishment of blood-nerve barrier [GO:0008065]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; response to estrogen [GO:0043627]; xenobiotic catabolic process [GO:0042178] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; nucleus [GO:0005634]; sperm fibrous sheath [GO:0035686] enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803] 0.39492 0.70832 KHNMCGETEEEK 0 0 0 0 0 11.5591 0 0 0 16.0522 0 0 0 0 12.5524 0 0 0 0 0 0 0 0 0 0 0 0 P21281 VATB2_HUMAN "V-type proton ATPase subunit B, brain isoform (V-ATPase subunit B 2) (Endomembrane proton pump 58 kDa subunit) (HO57) (Vacuolar proton pump subunit B 2)" ATP6V1B2 ATP6B2 VPP3 Homo sapiens (Human) ATP metabolic process [GO:0046034]; proton transmembrane transport [GO:1902600]; regulation of macroautophagy [GO:0016241]; synaptic vesicle lumen acidification [GO:0097401]; vacuolar acidification [GO:0007035] "apical plasma membrane [GO:0016324]; clathrin-coated vesicle membrane [GO:0030665]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of synaptic vesicle membrane [GO:0098850]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; melanosome [GO:0042470]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]" "ATP binding [GO:0005524]; proton transmembrane transporter activity [GO:0015078]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]" 0.84783 0.1292 KTSCEFTGDILRTPVSEDMLGR 11.0367 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P21283 VATC1_HUMAN V-type proton ATPase subunit C 1 (V-ATPase subunit C 1) (Vacuolar proton pump subunit C 1) ATP6V1C1 ATP6C ATP6D VATC Homo sapiens (Human) proton transmembrane transport [GO:1902600]; regulation of macroautophagy [GO:0016241]; synaptic vesicle lumen acidification [GO:0097401] "apical part of cell [GO:0045177]; clathrin-coated vesicle membrane [GO:0030665]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of synaptic vesicle membrane [GO:0098850]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; proton-transporting two-sector ATPase complex [GO:0016469]; transmembrane transporter complex [GO:1902495]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]" "proton-transporting ATPase activity, rotational mechanism [GO:0046961]" 0.91981 -0.93027 GNLQNLER 9.84027 0 0 0 0 0 0 0 0 0 12.173 0 0 0 0 0 0 0 0 9.9497 0 10.7263 0 0 0 0 0 P21291 CSRP1_HUMAN Cysteine and glycine-rich protein 1 (Cysteine-rich protein 1) (CRP) (CRP1) (Epididymis luminal protein 141) (HEL-141) CSRP1 CSRP CYRP Homo sapiens (Human) muscle tissue development [GO:0060537]; platelet aggregation [GO:0070527]; sarcomere organization [GO:0045214] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; Z disc [GO:0030018] actinin binding [GO:0042805]; RNA binding [GO:0003723]; structural constituent of muscle [GO:0008307]; zinc ion binding [GO:0008270] 0.43379 0.65402 GFGFGQGAGALVHSE 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7.9384 10.2456 9.97542 10.6682 0 9.62416 0 0 0 0 P21333 FLNA_HUMAN Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) FLNA FLN FLN1 Homo sapiens (Human) "actin crosslink formation [GO:0051764]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319]" actin cytoskeleton [GO:0015629]; actin filament bundle [GO:0032432]; axonal growth cone [GO:0044295]; brush border [GO:0005903]; cell cortex [GO:0005938]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glycoprotein Ib-IX-V complex [GO:1990779]; membrane [GO:0016020]; Myb complex [GO:0031523]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; Z disc [GO:0030018] actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; DNA-binding transcription factor binding [GO:0140297]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; kinase binding [GO:0019900]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; protein kinase C binding [GO:0005080]; RNA binding [GO:0003723]; small GTPase binding [GO:0031267]; transmembrane transporter binding [GO:0044325] 0 32.669 AEAGVPAEFSIWTR 11.4072 11.5858 11.7952 0 0 0 10.9929 12.3885 11.7118 11.8115 0 0 0 10.132 10.2164 0 10.6014 11.219 0 0 0 0 9.84105 9.41602 12.7781 0 0 P21359 NF1_HUMAN Neurofibromin (Neurofibromatosis-related protein NF-1) [Cleaved into: Neurofibromin truncated] NF1 Homo sapiens (Human) "actin cytoskeleton organization [GO:0030036]; adrenal gland development [GO:0030325]; amygdala development [GO:0021764]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; brain development [GO:0007420]; camera-type eye morphogenesis [GO:0048593]; cell communication [GO:0007154]; cellular response to heat [GO:0034605]; cerebral cortex development [GO:0021987]; cognition [GO:0050890]; collagen fibril organization [GO:0030199]; endothelial cell proliferation [GO:0001935]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; fibroblast proliferation [GO:0048144]; forebrain astrocyte development [GO:0021897]; forebrain morphogenesis [GO:0048853]; gamma-aminobutyric acid secretion, neurotransmission [GO:0061534]; glutamate secretion, neurotransmission [GO:0061535]; hair follicle maturation [GO:0048820]; heart development [GO:0007507]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; mast cell apoptotic process [GO:0033024]; mast cell proliferation [GO:0070662]; metanephros development [GO:0001656]; myelination in peripheral nervous system [GO:0022011]; myeloid leukocyte migration [GO:0097529]; negative regulation of angiogenesis [GO:0016525]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of mast cell proliferation [GO:0070667]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of neurotransmitter secretion [GO:0046929]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of protein import into nucleus [GO:0042308]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of Rac protein signal transduction [GO:0035021]; negative regulation of Schwann cell migration [GO:1900148]; negative regulation of Schwann cell proliferation [GO:0010626]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; neural tube development [GO:0021915]; neuroblast proliferation [GO:0007405]; neuron apoptotic process [GO:0051402]; observational learning [GO:0098597]; oligodendrocyte differentiation [GO:0048709]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; pigmentation [GO:0043473]; positive regulation of adenylate cyclase activity [GO:0045762]; positive regulation of apoptotic process [GO:0043065]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of GTPase activity [GO:0043547]; positive regulation of mast cell apoptotic process [GO:0033027]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; protein import into nucleus [GO:0006606]; Rac protein signal transduction [GO:0016601]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of bone resorption [GO:0045124]; regulation of cell-matrix adhesion [GO:0001952]; regulation of gene expression [GO:0010468]; regulation of glial cell differentiation [GO:0045685]; regulation of GTPase activity [GO:0043087]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of postsynapse organization [GO:0099175]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to hypoxia [GO:0001666]; Schwann cell development [GO:0014044]; Schwann cell migration [GO:0036135]; Schwann cell proliferation [GO:0014010]; skeletal muscle tissue development [GO:0007519]; smooth muscle tissue development [GO:0048745]; spinal cord development [GO:0021510]; stem cell proliferation [GO:0072089]; sympathetic nervous system development [GO:0048485]; vascular associated smooth muscle cell migration [GO:1904738]; vascular associated smooth muscle cell proliferation [GO:1990874]; visual learning [GO:0008542]; wound healing [GO:0042060]" axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; presynapse [GO:0098793] GTPase activator activity [GO:0005096]; phosphatidylcholine binding [GO:0031210]; phosphatidylethanolamine binding [GO:0008429] 0.88498 -0.3779 IDAVYCHSVELR 13.0579 0 12.4785 9.97728 0 10.7131 11.104 8.99831 0 0 0 0 0 0 0 9.54963 11.6826 0 9.81356 9.21519 9.84867 9.06996 0 0 10.7587 9.76408 9.46371 P21397 AOFA_HUMAN Amine oxidase [flavin-containing] A (EC 1.4.3.21) (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A) MAOA Homo sapiens (Human) biogenic amine metabolic process [GO:0006576]; dopamine catabolic process [GO:0042420]; neurotransmitter catabolic process [GO:0042135]; positive regulation of signal transduction [GO:0009967] cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739] aliphatic amine oxidase activity [GO:0052595]; monoamine oxidase activity [GO:0097621]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131] 0.87255 0.031415 DVPAVEITHTFWER 0 0 0 0 0 0 0 0 0 0 0 9.49448 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P21399 ACOHC_HUMAN Cytoplasmic aconitate hydratase (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase) (Ferritin repressor protein) (Iron regulatory protein 1) (IRP1) (Iron-responsive element-binding protein 1) (IRE-BP 1) ACO1 IREB1 Homo sapiens (Human) citrate metabolic process [GO:0006101]; intestinal absorption [GO:0050892]; intracellular iron ion homeostasis [GO:0006879]; post-embryonic development [GO:0009791]; regulation of translation [GO:0006417]; response to iron(II) ion [GO:0010040]; tricarboxylic acid cycle [GO:0006099] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; mitochondrion [GO:0005739] "3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; citrate dehydratase activity [GO:0047780]; iron-responsive element binding [GO:0030350]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]" 0.92428 -1.0338 NQDLEFERNRER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.35669 0 0 0 0 0 0 0 0 0 0 0 0 P21452 NK2R_HUMAN Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) TACR2 NK2R NKNAR TAC2R Homo sapiens (Human) "intestine smooth muscle contraction [GO:0014827]; muscle contraction [GO:0006936]; negative regulation of luteinizing hormone secretion [GO:0033685]; operant conditioning [GO:0035106]; positive regulation of acetylcholine secretion, neurotransmission [GO:0014057]; positive regulation of flagellated sperm motility [GO:1902093]; positive regulation of monoatomic ion transport [GO:0043270]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of uterine smooth muscle contraction [GO:0070474]; positive regulation of vascular permeability [GO:0043117]; prolactin secretion [GO:0070459]; response to electrical stimulus [GO:0051602]; tachykinin receptor signaling pathway [GO:0007217]" plasma membrane [GO:0005886]; sperm flagellum [GO:0036126]; sperm head [GO:0061827]; sperm midpiece [GO:0097225] substance K receptor activity [GO:0016497]; tachykinin receptor activity [GO:0004995] 0.83076 0.20244 AVPGHQAHGANLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.52886 0 0 0 P21453 S1PR1_HUMAN Sphingosine 1-phosphate receptor 1 (S1P receptor 1) (S1P1) (Endothelial differentiation G-protein coupled receptor 1) (Sphingosine 1-phosphate receptor Edg-1) (S1P receptor Edg-1) (CD antigen CD363) S1PR1 CHEDG1 EDG1 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; angiogenesis [GO:0001525]; blood vessel maturation [GO:0001955]; brain development [GO:0007420]; cardiac muscle tissue growth involved in heart morphogenesis [GO:0003245]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; chemotaxis [GO:0006935]; endothelial cell differentiation [GO:0045446]; G protein-coupled receptor signaling pathway [GO:0007186]; heart trabecula morphogenesis [GO:0061384]; lamellipodium assembly [GO:0030032]; leukocyte chemotaxis [GO:0030595]; negative regulation of stress fiber assembly [GO:0051497]; neuron differentiation [GO:0030182]; positive regulation of cell migration [GO:0030335]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of GTPase activity [GO:0043547]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of bone mineralization [GO:0030500]; regulation of bone resorption [GO:0045124]; regulation of cell adhesion [GO:0030155]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; T cell migration [GO:0072678]; transmission of nerve impulse [GO:0019226] endosome [GO:0005768]; external side of plasma membrane [GO:0009897]; intracellular membrane-bounded organelle [GO:0043231]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; G protein-coupled receptor binding [GO:0001664]; sphingolipid binding [GO:0046625]; sphingosine-1-phosphate receptor activity [GO:0038036] 0.95913 -1.7698 LNISADKENSIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.46999 0 0 0 0 0 0 0 0 0 0 8.59466 P21506 ZNF10_HUMAN Zinc finger protein 10 (Zinc finger protein KOX1) ZNF10 KOX1 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634]; protein-containing complex [GO:0032991] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.60988 0.42954 GEEPWLVER 0 0 0 0 0 0 0 0 0 0 9.28612 0 0 0 0 0 0 0 0 0 0 8.82563 0 0 0 0 10.09 P21580 TNAP3_HUMAN Tumor necrosis factor alpha-induced protein 3 (TNF alpha-induced protein 3) (EC 2.3.2.-) (EC 3.4.19.12) (OTU domain-containing protein 7C) (Putative DNA-binding protein A20) (Zinc finger protein A20) [Cleaved into: A20p50; A20p37] TNFAIP3 OTUD7C Homo sapiens (Human) apoptotic process [GO:0006915]; B-1 B cell homeostasis [GO:0001922]; cell migration [GO:0016477]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cytoskeleton organization [GO:0007010]; establishment of protein localization to vacuole [GO:0072666]; inflammatory response [GO:0006954]; negative regulation of B cell activation [GO:0050869]; negative regulation of bone resorption [GO:0045779]; negative regulation of CD40 signaling pathway [GO:2000349]; negative regulation of chronic inflammatory response [GO:0002677]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070429]; negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070433]; negative regulation of osteoclast proliferation [GO:0090291]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of toll-like receptor 3 signaling pathway [GO:0034140]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of toll-like receptor 5 signaling pathway [GO:0034148]; negative regulation of tumor necrosis factor production [GO:0032720]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of Wnt signaling pathway [GO:0030177]; protein deubiquitination [GO:0016579]; protein deubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0071947]; protein K11-linked deubiquitination [GO:0035871]; protein K29-linked deubiquitination [GO:0035523]; protein K33-linked deubiquitination [GO:1990168]; protein K48-linked deubiquitination [GO:0071108]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked deubiquitination [GO:0070536]; regulation of defense response to virus by host [GO:0050691]; regulation of germinal center formation [GO:0002634]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; regulation of vascular wound healing [GO:0061043]; response to molecule of bacterial origin [GO:0002237]; response to muramyl dipeptide [GO:0032495]; tolerance induction to lipopolysaccharide [GO:0072573] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; nucleus [GO:0005634] cysteine-type deubiquitinase activity [GO:0004843]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; K63-linked deubiquitinase activity [GO:0061578]; K63-linked polyubiquitin modification-dependent protein binding [GO:0070530]; kinase binding [GO:0019900]; protease binding [GO:0002020]; protein self-association [GO:0043621]; ubiquitin binding [GO:0043130]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.96874 -5.7843 EIIHKALIDR 0 0 0 0 0 0 0 0 0 0 0 0 8.96988 0 8.83194 9.81489 0 0 0 0 0 10.7504 0 0 0 0 0 P21583 SCF_HUMAN Kit ligand (Mast cell growth factor) (MGF) (Stem cell factor) (SCF) (c-Kit ligand) [Cleaved into: Soluble KIT ligand (sKITLG)] KITLG MGF SCF Homo sapiens (Human) cell adhesion [GO:0007155]; ectopic germ cell programmed cell death [GO:0035234]; embryonic hemopoiesis [GO:0035162]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; hematopoietic progenitor cell differentiation [GO:0002244]; male gonad development [GO:0008584]; mast cell apoptotic process [GO:0033024]; mast cell migration [GO:0097531]; mast cell proliferation [GO:0070662]; melanocyte migration [GO:0097324]; myeloid leukocyte differentiation [GO:0002573]; negative regulation of mast cell apoptotic process [GO:0033026]; neural crest cell migration [GO:0001755]; ovarian follicle development [GO:0001541]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of hematopoietic progenitor cell differentiation [GO:1901534]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell proliferation [GO:0070668]; positive regulation of melanocyte differentiation [GO:0045636]; positive regulation of myeloid leukocyte differentiation [GO:0002763]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of T cell proliferation [GO:0042102]; Ras protein signal transduction [GO:0007265]; response to organic cyclic compound [GO:0014070]; T cell proliferation [GO:0042098] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886] cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; stem cell factor receptor binding [GO:0005173] 0.91737 -0.85306 LFTPEEFFR 11.4762 11.453 0 0 0 0 0 10.8308 0 0 11.464 0 10.2022 0 0 10.9585 11.1427 10.6468 0 0 0 0 0 0 10.6508 0 0 P21695 GPDA_HUMAN "Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic (GPD-C) (GPDH-C) (EC 1.1.1.8)" GPD1 Homo sapiens (Human) cellular response to cAMP [GO:0071320]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glycerol-3-phosphate catabolic process [GO:0046168]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerolipid metabolic process [GO:0046486]; glycerophosphate shuttle [GO:0006127]; NADH metabolic process [GO:0006734]; NADH oxidation [GO:0006116]; positive regulation of glycolytic process [GO:0045821] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glycerol-3-phosphate dehydrogenase complex [GO:0009331] glycerol-3-phosphate dehydrogenase (quinone) activity [GO:0004368]; glycerol-3-phosphate dehydrogenase [NAD(P)+] activity [GO:0047952]; NAD binding [GO:0051287]; protein homodimerization activity [GO:0042803] 0.80958 0.23204 FPLFMAVYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.6778 0 P21709 EPHA1_HUMAN Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) (EPH tyrosine kinase 1) (Erythropoietin-producing hepatoma receptor) (Tyrosine-protein kinase receptor EPH) EPHA1 EPH EPHT EPHT1 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; angiogenesis [GO:0001525]; cell surface receptor signaling pathway [GO:0007166]; ephrin receptor signaling pathway [GO:0048013]; negative regulation of cell migration [GO:0030336]; negative regulation of protein kinase activity [GO:0006469]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of kinase activity [GO:0033674]; positive regulation of stress fiber assembly [GO:0051496]; protein autophosphorylation [GO:0046777]; regulation of GTPase activity [GO:0043087]; substrate adhesion-dependent cell spreading [GO:0034446] plasma membrane [GO:0005886]; receptor complex [GO:0043235] ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005] 0.95888 -1.7811 ATDVDREDK 0 0 0 9.72204 0 0 0 0 0 0 0 0 0 9.71127 0 0 0 0 0 0 0 0 0 0 0 0 0 P21741 MK_HUMAN Midkine (MK) (Amphiregulin-associated protein) (ARAP) (Midgestation and kidney protein) (Neurite outgrowth-promoting factor 2) (Neurite outgrowth-promoting protein) MDK MK1 NEGF2 Homo sapiens (Human) adrenal gland development [GO:0030325]; behavioral fear response [GO:0001662]; cell differentiation [GO:0030154]; cerebellar granular layer development [GO:0021681]; cerebral cortex development [GO:0021987]; cytoskeleton organization [GO:0007010]; defecation [GO:0030421]; dentate gyrus development [GO:0021542]; estrous cycle [GO:0044849]; glial cell projection elongation [GO:0106091]; intracellular signal transduction [GO:0035556]; leukocyte chemotaxis involved in inflammatory response [GO:0002232]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of cell adhesion [GO:0007162]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of inflammatory response to wounding [GO:0106015]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of ossification [GO:0030279]; negative regulation of regulatory T cell differentiation [GO:0045590]; nervous system development [GO:0007399]; oogenesis [GO:0048477]; positive regulation of artery morphogenesis [GO:1905653]; positive regulation of blood vessel branching [GO:1905555]; positive regulation of cartilage development [GO:0061036]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of inflammatory response [GO:0050729]; positive regulation of inflammatory response to wounding [GO:0106016]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of leukocyte cell-cell adhesion [GO:1903039]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of neuron projection development [GO:0010976]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of smooth muscle cell chemotaxis [GO:0071673]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; regulation of behavior [GO:0050795]; regulation of bone remodeling [GO:0046850]; regulation of chondrocyte differentiation [GO:0032330]; response to auditory stimulus [GO:0010996]; response to glucocorticoid [GO:0051384]; response to wounding [GO:0009611]; response to xenobiotic stimulus [GO:0009410]; short-term memory [GO:0007614]; signal transduction [GO:0007165]; T cell activation involved in immune response [GO:0002286]; tissue regeneration [GO:0042246] cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular region [GO:0005576] chondroitin sulfate binding [GO:0035374]; growth factor activity [GO:0008083]; heparan sulfate binding [GO:1904399]; heparin binding [GO:0008201] 0.96355 -2.1336 EFGADCKYK 0 0 0 0 0 0 0 0 0 10.9102 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P21757 MSRE_HUMAN Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor class A member 1) (CD antigen CD204) MSR1 SCARA1 Homo sapiens (Human) "amyloid-beta clearance [GO:0097242]; cellular response to organic cyclic compound [GO:0071407]; cholesterol transport [GO:0030301]; establishment of localization in cell [GO:0051649]; lipoprotein transport [GO:0042953]; negative regulation of gene expression [GO:0010629]; phagocytosis, engulfment [GO:0006911]; plasma lipoprotein particle clearance [GO:0034381]; positive regulation of cholesterol storage [GO:0010886]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; receptor-mediated endocytosis [GO:0006898]" collagen trimer [GO:0005581]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; low-density lipoprotein particle [GO:0034362]; membrane [GO:0016020]; plasma membrane [GO:0005886] amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; low-density lipoprotein particle binding [GO:0030169]; scavenger receptor activity [GO:0005044] 0.86249 0.095643 ACSHSEDAGVTCTL 0 0 0 0 0 0 0 11.9801 11.7224 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P21781 FGF7_HUMAN Fibroblast growth factor 7 (FGF-7) (Heparin-binding growth factor 7) (HBGF-7) (Keratinocyte growth factor) FGF7 KGF Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; animal organ morphogenesis [GO:0009887]; branching involved in salivary gland morphogenesis [GO:0060445]; cell differentiation [GO:0030154]; endothelial cell proliferation [GO:0001935]; epidermis development [GO:0008544]; fibroblast growth factor receptor signaling pathway [GO:0008543]; hair follicle morphogenesis [GO:0031069]; lung development [GO:0030324]; mesenchymal cell proliferation [GO:0010463]; myoblast proliferation [GO:0051450]; positive chemotaxis [GO:0050918]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of myoblast proliferation [GO:2000288]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; protein localization to cell surface [GO:0034394]; regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling [GO:0060665]; regulation of cell migration [GO:0030334]; response to wounding [GO:0009611]; secretion by lung epithelial cell involved in lung growth [GO:0061033]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794] chemoattractant activity [GO:0042056]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; type 2 fibroblast growth factor receptor binding [GO:0005111] 0.93305 -1.2656 ELILENHYNTYASAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.64243 0 0 0 0 0 0 0 0 0 0 0 0 P21796 VDAC1_HUMAN Voltage-dependent anion-selective channel protein 1 (VDAC-1) (hVDAC1) (Outer mitochondrial membrane protein porin 1) (Plasmalemmal porin) (Porin 31HL) (Porin 31HM) VDAC1 VDAC Homo sapiens (Human) apoptotic process [GO:0006915]; behavioral fear response [GO:0001662]; epithelial cell differentiation [GO:0030855]; learning [GO:0007612]; monoatomic anion transport [GO:0006820]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcium import into the mitochondrion [GO:0110099]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; neuron-neuron synaptic transmission [GO:0007270]; positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:1905091]; pyruvate metabolic process [GO:0006090]; regulation of autophagy of mitochondrion [GO:1903146] extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; mitochondrial nucleoid [GO:0042645]; mitochondrial outer membrane [GO:0005741]; mitochondrial permeability transition pore complex [GO:0005757]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; pore complex [GO:0046930]; synapse [GO:0045202] ceramide binding [GO:0097001]; cholesterol binding [GO:0015485]; identical protein binding [GO:0042802]; phosphatidylcholine binding [GO:0031210]; porin activity [GO:0015288]; protein kinase binding [GO:0019901]; transmembrane transporter binding [GO:0044325]; voltage-gated monoatomic anion channel activity [GO:0008308] 0 15.763 AVPPTYADLGK 0 0 0 0 0 0 0 0 0 0 0 0 9.26709 0 0 10.3162 0 9.38282 11.9205 10.8277 12.6207 10.8619 0 11.7452 12.6193 12.7332 12.6112 P21802 FGFR2_HUMAN Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332) FGFR2 BEK KGFR KSAM Homo sapiens (Human) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060] cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713] 0.78536 0.24894 DLVSCTYQLAR 0 0 0 0 0 0 0 0 0 0 0 0 10.0253 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P21810 PGS1_HUMAN Biglycan (Bone/cartilage proteoglycan I) (PG-S1) BGN SLRR1A Homo sapiens (Human) articular cartilage development [GO:0061975]; bone development [GO:0060348]; peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan [GO:0019800] cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; lysosomal lumen [GO:0043202]; sarcolemma [GO:0042383]; transport vesicle [GO:0030133] cytokine binding [GO:0019955]; extracellular matrix binding [GO:0050840]; extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring compression resistance [GO:0030021]; glycosaminoglycan binding [GO:0005539] 0.80379 0.24065 VVQCSDLGLK 0 0 0 0 0 0 0 0 0 0 10.0188 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P21815 SIAL_HUMAN Bone sialoprotein 2 (Bone sialoprotein II) (BSP II) (Cell-binding sialoprotein) (Integrin-binding sialoprotein) IBSP BNSP Homo sapiens (Human) bone mineralization [GO:0030282]; cell adhesion [GO:0007155]; cellular response to growth factor stimulus [GO:0071363]; extracellular matrix organization [GO:0030198]; osteoblast differentiation [GO:0001649]; positive regulation of cell adhesion [GO:0045785] extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; vesicle [GO:0031982] integrin binding [GO:0005178]; small molecule binding [GO:0036094] 0.63179 0.39792 AGDITNK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.00208 0 0 0 0 0 0 0 0 0 0 0 0 0 P21817 RYR1_HUMAN Ryanodine receptor 1 (RYR-1) (RyR1) (Skeletal muscle calcium release channel) (Skeletal muscle ryanodine receptor) (Skeletal muscle-type ryanodine receptor) (Type 1 ryanodine receptor) RYR1 RYDR Homo sapiens (Human) calcium ion transport [GO:0006816]; cellular response to caffeine [GO:0071313]; cellular response to calcium ion [GO:0071277]; muscle contraction [GO:0006936]; ossification involved in bone maturation [GO:0043931]; outflow tract morphogenesis [GO:0003151]; protein homotetramerization [GO:0051289]; regulation of cytosolic calcium ion concentration [GO:0051480]; release of sequestered calcium ion into cytosol [GO:0051209]; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0014808]; response to caffeine [GO:0031000]; response to hypoxia [GO:0001666]; skeletal muscle fiber development [GO:0048741]; skin development [GO:0043588]; striated muscle contraction [GO:0006941] calcium channel complex [GO:0034704]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; I band [GO:0031674]; junctional sarcoplasmic reticulum membrane [GO:0014701]; organelle membrane [GO:0031090]; plasma membrane [GO:0005886]; ryanodine receptor complex [GO:1990425]; sarcolemma [GO:0042383]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; smooth endoplasmic reticulum [GO:0005790]; terminal cisterna [GO:0014802]; Z disc [GO:0030018] ATP binding [GO:0005524]; calcium channel activity [GO:0005262]; calcium ion binding [GO:0005509]; calcium-induced calcium release activity [GO:0048763]; calcium-release channel activity [GO:0015278]; calmodulin binding [GO:0005516]; ryanodine-sensitive calcium-release channel activity [GO:0005219]; voltage-gated calcium channel activity [GO:0005245] 0.96962 -5.0421 CMDILELSER 0 0 0 0 0 0 9.68745 0 0 0 0 0 0 0 0 9.93001 0 0 0 10.4041 0 0 0 0 0 0 10.7554 P21917 DRD4_HUMAN D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor) DRD4 Homo sapiens (Human) "adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; adenylate cyclase-inhibiting serotonin receptor signaling pathway [GO:0007198]; adult locomotory behavior [GO:0008344]; arachidonic acid secretion [GO:0050482]; behavioral fear response [GO:0001662]; behavioral response to cocaine [GO:0048148]; behavioral response to ethanol [GO:0048149]; chemical synaptic transmission [GO:0007268]; dopamine metabolic process [GO:0042417]; dopamine receptor signaling pathway [GO:0007212]; fear response [GO:0042596]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; inhibitory postsynaptic potential [GO:0060080]; intracellular calcium ion homeostasis [GO:0006874]; negative regulation of protein secretion [GO:0050709]; negative regulation of voltage-gated calcium channel activity [GO:1901386]; positive regulation of dopamine uptake involved in synaptic transmission [GO:0051586]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of sodium:proton antiporter activity [GO:0032417]; regulation of circadian rhythm [GO:0042752]; regulation of dopamine metabolic process [GO:0042053]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; response to amphetamine [GO:0001975]; response to histamine [GO:0034776]; rhythmic process [GO:0048511]; social behavior [GO:0035176]" centrosome [GO:0005813]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794] "dopamine binding [GO:0035240]; dopamine neurotransmitter receptor activity [GO:0004952]; dopamine neurotransmitter receptor activity, coupled via Gi/Go [GO:0001591]; epinephrine binding [GO:0051379]; G protein-coupled serotonin receptor activity [GO:0004993]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; neurotransmitter receptor activity [GO:0030594]; norepinephrine binding [GO:0051380]; potassium channel regulator activity [GO:0015459]; serotonin binding [GO:0051378]; SH3 domain binding [GO:0017124]" 0.88523 -0.38014 GLQRWEVAR 0 0 0 0 0 0 0 9.29928 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P21926 CD9_HUMAN CD9 antigen (5H9 antigen) (Cell growth-inhibiting gene 2 protein) (Leukocyte antigen MIC3) (Motility-related protein) (MRP-1) (Tetraspanin-29) (Tspan-29) (p24) (CD antigen CD9) CD9 MIC3 TSPAN29 GIG2 Homo sapiens (Human) cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; fusion of sperm to egg plasma membrane involved in single fertilization [GO:0007342]; glial cell migration [GO:0008347]; myoblast fusion involved in skeletal muscle regeneration [GO:0014905]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of platelet aggregation [GO:0090331]; paranodal junction assembly [GO:0030913]; platelet activation [GO:0030168]; receptor internalization [GO:0031623]; regulation of macrophage migration [GO:1905521]; sperm-egg recognition [GO:0035036] clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; focal adhesion [GO:0005925]; membrane [GO:0016020]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; protein-containing complex [GO:0032991] integrin binding [GO:0005178] 0.22787 0.87542 DVLETFTVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.01131 0 10.8173 10.0229 10.8189 10.7685 0 11.7911 10.4323 11.1503 P21964 COMT_HUMAN Catechol O-methyltransferase (EC 2.1.1.6) COMT Homo sapiens (Human) catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; lipid metabolic process [GO:0006629]; methylation [GO:0032259]; neurotransmitter catabolic process [GO:0042135] axon [GO:0030424]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; plasma membrane [GO:0005886] catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; methyltransferase activity [GO:0008168]; O-methyltransferase activity [GO:0008171]; orcinol O-methyltransferase activity [GO:0102938] 0.90945 -0.74483 AIYKGPGSEAGP 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3927 0 0 0 0 0 0 0 0 0 P21980 TGM2_HUMAN Protein-glutamine gamma-glutamyltransferase 2 (EC 2.3.2.13) (Erythrocyte transglutaminase) (Heart G alpha(h)) (hhG alpha(h)) (Isopeptidase TGM2) (EC 3.4.-.-) (Protein G alpha(h)) (G(h)) (Protein-glutamine deamidase TGM2) (EC 3.5.1.44) (Protein-glutamine dopaminyltransferase TGM2) (EC 2.3.1.-) (Protein-glutamine histaminyltransferase TGM2) (EC 2.3.1.-) (Protein-glutamine noradrenalinyltransferase TGM2) (EC 2.3.1.-) (Protein-glutamine serotonyltransferase TGM2) (EC 2.3.1.-) (Tissue transglutaminase) (tTG) (tTgase) (Transglutaminase C) (TG(C)) (TGC) (TGase C) (Transglutaminase H) (TGase H) (Transglutaminase II) (TGase II) (Transglutaminase-2) (TG2) (TGase-2) (hTG2) TGM2 Homo sapiens (Human) apoptotic cell clearance [GO:0043277]; bone development [GO:0060348]; branching involved in salivary gland morphogenesis [GO:0060445]; cellular response to cocaine [GO:0071314]; cellular response to dopamine [GO:1903351]; cellular response to serotonin [GO:1904015]; dopamine secretion [GO:0014046]; gene expression [GO:0010467]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of GTPase activity [GO:0043547]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of neurogenesis [GO:0050769]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; protein deamination [GO:0018277]; protein homooligomerization [GO:0051260]; proteolysis [GO:0006508]; regulation of apoptotic cell clearance [GO:2000425]; regulation of apoptotic process [GO:0042981]; salivary gland cavitation [GO:0060662] chromatin [GO:0000785]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; focal adhesion [GO:0005925]; mitochondrion [GO:0005739]; nucleosome [GO:0000786]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; GTP binding [GO:0005525]; histone dopaminyltransferase activity [GO:0120297]; histone serotonyltransferase activity [GO:0120295]; peptidase activity [GO:0008233]; peptide histaminyltransferase activity [GO:0120299]; peptide noradrenalinyltransferase activity [GO:0120298]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; protein-glutamine glutaminase activity [GO:0050568] 0.473 0.6275 AEELVLER 0 0 0 9.33284 0 0 0 8.36588 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8742 0 0 P22003 BMP5_HUMAN Bone morphogenetic protein 5 (BMP-5) BMP5 Homo sapiens (Human) allantois development [GO:1905069]; anterior head development [GO:0097065]; cardiac muscle tissue development [GO:0048738]; cardiac septum morphogenesis [GO:0060411]; cartilage development [GO:0051216]; chorio-allantoic fusion [GO:0060710]; ear development [GO:0043583]; endocardial cushion formation [GO:0003272]; heart trabecula morphogenesis [GO:0061384]; hindbrain development [GO:0030902]; male genitalia development [GO:0030539]; negative regulation of aldosterone biosynthetic process [GO:0032348]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cortisol biosynthetic process [GO:2000065]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of insulin-like growth factor receptor signaling pathway [GO:0043569]; negative regulation of mononuclear cell migration [GO:0071676]; negative regulation of steroid biosynthetic process [GO:0010894]; neural fold elevation formation [GO:0021502]; ossification [GO:0001503]; pattern specification process [GO:0007389]; pericardium morphogenesis [GO:0003344]; pharyngeal system development [GO:0060037]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of dendrite development [GO:1900006]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transcription by RNA polymerase II [GO:0045944]; skeletal system development [GO:0001501]; SMAD protein signal transduction [GO:0060395]; type B pancreatic cell development [GO:0003323] extracellular space [GO:0005615]; vesicle [GO:0031982] BMP receptor binding [GO:0070700]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083] 0.60571 0.43847 ASLAEETR 0 0 0 0 0 0 0 0 0 8.16581 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P22033 MUTA_HUMAN "Methylmalonyl-CoA mutase, mitochondrial (MCM) (EC 5.4.99.2) (Methylmalonyl-CoA isomerase)" MMUT MUT Homo sapiens (Human) "homocysteine metabolic process [GO:0050667]; positive regulation of GTPase activity [GO:0043547]; post-embryonic development [GO:0009791]; propionate metabolic process, methylmalonyl pathway [GO:0019678]; succinyl-CoA biosynthetic process [GO:1901290]" cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] cobalamin binding [GO:0031419]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]; modified amino acid binding [GO:0072341]; protein homodimerization activity [GO:0042803] 0.96755 -2.3424 AGRRLWAHLIEK 9.80621 0 0 0 0 0 0 0 0 10.882 10.8862 0 0 0 0 0 0 0 0 0 10.266 0 0 0 0 0 0 P22059 OSBP1_HUMAN Oxysterol-binding protein 1 OSBP OSBP1 Homo sapiens (Human) bile acid biosynthetic process [GO:0006699]; ceramide transport [GO:0035627]; intracellular cholesterol transport [GO:0032367]; phospholipid transport [GO:0015914]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of secretory granule organization [GO:1904411]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; sphingomyelin biosynthetic process [GO:0006686]; sterol transport [GO:0015918] cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; trans-Golgi network [GO:0005802] oxysterol binding [GO:0008142]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protein domain specific binding [GO:0019904]; sterol binding [GO:0032934]; sterol transfer activity [GO:0120015]; sterol transporter activity [GO:0015248] 0.80104 0.23946 IPMPVNFNEPLSMLQR 0 0 9.67981 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P22079 PERL_HUMAN Lactoperoxidase (LPO) (EC 1.11.1.7) (Salivary peroxidase) (SPO) LPO SAPX Homo sapiens (Human) defense response to bacterium [GO:0042742]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979] basolateral plasma membrane [GO:0016323]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615] heme binding [GO:0020037]; lactoperoxidase activity [GO:0140825]; metal ion binding [GO:0046872]; thiocyanate peroxidase activity [GO:0036393] 0.89852 -0.62183 CDPCSPYR 12.7177 12.7976 13.0591 0 0 0 12.5575 12.9944 12.915 12.9181 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P22087 FBRL_HUMAN rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (34 kDa nucleolar scleroderma antigen) (Histone-glutamine methyltransferase) (U6 snRNA 2'-O-methyltransferase fibrillarin) FBL FIB1 FLRN Homo sapiens (Human) box C/D RNA 3'-end processing [GO:0000494]; histone glutamine methylation [GO:1990258]; osteoblast differentiation [GO:0001649]; ribosomal small subunit biogenesis [GO:0042274]; rRNA methylation [GO:0031167]; rRNA processing [GO:0006364]; snoRNA localization [GO:0048254] box C/D RNP complex [GO:0031428]; Cajal body [GO:0015030]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; granular component [GO:0001652]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; small-subunit processome [GO:0032040] ATPase binding [GO:0051117]; histone H2AQ104 methyltransferase activity [GO:1990259]; RNA binding [GO:0003723]; rRNA methyltransferase activity [GO:0008649]; TFIID-class transcription factor complex binding [GO:0001094] 0.8837 -0.11907 RGNQSGKNVMVEPHR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.92892 0 0 0 0 0 0 0 0 0 0 0 0 0 P22090 RS4Y1_HUMAN "Small ribosomal subunit protein eS4, Y isoform 1 (40S ribosomal protein S4)" RPS4Y1 RPS4Y PRO2646 Homo sapiens (Human) translation [GO:0006412] cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; polysome [GO:0005844] RNA binding [GO:0003723]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735] 0.9603 -1.8079 KITVGVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4453 0 0 0 P22102 PUR2_HUMAN Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)] GART PGFT PRGS Homo sapiens (Human) 'de novo' AMP biosynthetic process [GO:0044208]; 'de novo' IMP biosynthetic process [GO:0006189]; 'de novo' XMP biosynthetic process [GO:0097294]; adenine biosynthetic process [GO:0046084]; brainstem development [GO:0003360]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; glycine metabolic process [GO:0006544]; GMP biosynthetic process [GO:0006177]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; response to organic substance [GO:0010033]; tetrahydrofolate biosynthetic process [GO:0046654] cytosol [GO:0005829]; extracellular exosome [GO:0070062] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; phosphoribosylglycinamide formyltransferase activity [GO:0004644] 0.96822 -3.8411 AIAFLQQPR 0 0 14.8156 10.3901 0 11.1899 0 0 0 0 0 15.0887 12.8854 12.7409 9.69014 0 0 0 10.1435 0 0 0 0 0 0 12.7068 9.11194 P22105 TENX_HUMAN Tenascin-X (TN-X) (Hexabrachion-like protein) TNXB HXBL TNX TNXB1 TNXB2 XB Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; elastic fiber assembly [GO:0048251]; fatty acid metabolic process [GO:0006631]; neuron projection development [GO:0031175]; positive regulation of cell fate determination [GO:1905935]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transforming growth factor beta activation [GO:1901390]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; regulation of JUN kinase activity [GO:0043506]; triglyceride metabolic process [GO:0006641] collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; tenascin complex [GO:0090733] collagen binding [GO:0005518]; collagen fibril binding [GO:0098633]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; integrin binding [GO:0005178] 0.96902 -10.65 AGPFSSR 0 9.78789 0 0 0 0 0 0 0 10.3753 0 0 11.9286 0 0 0 0 10.9279 10.6548 9.44087 0 10.0908 0 9.24332 0 0 0 P22223 CADH3_HUMAN Cadherin-3 (Placental cadherin) (P-cadherin) CDH3 CDHP Homo sapiens (Human) adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of tyrosinase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to xenobiotic stimulus [GO:0009410]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060] adherens junction [GO:0005912]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886] cadherin binding [GO:0045296]; calcium ion binding [GO:0005509] 0.84997 0.15864 EAEVTLEAGGAEQEPGQALGK 9.63012 0 0 0 0 0 10.4867 0 10.9563 0 9.95418 10.274 11.6457 0 0 0 0 12.0143 0 0 0 10.9347 10.0967 10.5426 0 0 11.4744 P22234 PUR6_HUMAN Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) [Includes: Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) (AIR carboxylase) (AIRC); Phosphoribosylaminoimidazole succinocarboxamide synthetase (EC 6.3.2.6) (SAICAR synthetase)] PAICS ADE2 AIRC PAIS Homo sapiens (Human) 'de novo' AMP biosynthetic process [GO:0044208]; 'de novo' IMP biosynthetic process [GO:0006189]; 'de novo' XMP biosynthetic process [GO:0097294]; GMP biosynthetic process [GO:0006177]; purine nucleobase biosynthetic process [GO:0009113] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020] 5-amino-4-imidazole carboxylate lyase activity [GO:0043727]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]; phosphoribosylaminoimidazolesuccinocarboxamide synthase activity [GO:0004639] 0 23.862 ASILNTWISLK 0 0 0 0 0 0 10.5742 9.10043 10.1362 10.8271 10.2367 10.9448 10.1179 8.80584 9.40178 10.7299 10.8164 0 0 0 10.4613 8.22983 0 0 10.4179 0 9.91577 P22304 IDS_HUMAN Iduronate 2-sulfatase (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase) (Idursulfase) [Cleaved into: Iduronate 2-sulfatase 42 kDa chain; Iduronate 2-sulfatase 14 kDa chain] IDS SIDS Homo sapiens (Human) dermatan sulfate catabolic process [GO:0030209]; glycosaminoglycan catabolic process [GO:0006027]; heparan sulfate proteoglycan catabolic process [GO:0030200] cytoplasm [GO:0005737]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764] calcium ion binding [GO:0005509]; iduronate-2-sulfatase activity [GO:0004423] 0.95565 -1.5831 NLLKHFR 0 0 0 0 0 0 0 0 0 0 0 12.1388 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P22307 SCP2_HUMAN Sterol carrier protein 2 (SCP-2) (Acetyl-CoA C-myristoyltransferase) (EC 2.3.1.155) (Non-specific lipid-transfer protein) (NSL-TP) (Propanoyl-CoA C-acyltransferase) (EC 2.3.1.176) (SCP-2/3-oxoacyl-CoA thiolase) (SCP-2/thiolase) (EC 2.3.1.16) (SCP-chi) (SCPX) (Sterol carrier protein X) (SCP-X) SCP2 Homo sapiens (Human) alpha-linolenic acid metabolic process [GO:0036109]; bile acid biosynthetic process [GO:0006699]; bile acid metabolic process [GO:0008206]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; inositol trisphosphate biosynthetic process [GO:0032959]; intracellular cholesterol transport [GO:0032367]; lipid hydroperoxide transport [GO:1901373]; phospholipid transport [GO:0015914]; positive regulation of intracellular cholesterol transport [GO:0032385]; positive regulation of steroid metabolic process [GO:0045940]; progesterone biosynthetic process [GO:0006701]; protein localization to plasma membrane [GO:0072659]; regulation of phospholipid biosynthetic process [GO:0071071]; steroid biosynthetic process [GO:0006694] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991] acetyl-CoA C-acyltransferase activity [GO:0003988]; acetyl-CoA C-myristoyltransferase activity [GO:0050633]; cholesterol binding [GO:0015485]; cholesterol transfer activity [GO:0120020]; fatty-acyl-CoA binding [GO:0000062]; long-chain fatty acyl-CoA binding [GO:0036042]; oleic acid binding [GO:0070538]; phosphatidylcholine transfer activity [GO:0120019]; phosphatidylinositol transfer activity [GO:0008526]; propanoyl-CoA C-acyltransferase activity [GO:0033814]; propionyl-CoA C2-trimethyltridecanoyltransferase activity [GO:0050632]; signaling receptor binding [GO:0005102]; sterol binding [GO:0032934] 0.85022 0.11846 IGGIFAFK 8.73149 8.62783 8.76212 0 0 0 0 0 0 0 0 9.7979 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P22314 UBA1_HUMAN Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1) UBA1 A1S9T UBE1 Homo sapiens (Human) DNA damage response [GO:0006974]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; RNA binding [GO:0003723]; ubiquitin activating enzyme activity [GO:0004839] 0 161.97 AAVATFLQSVQVPEFTPK 10.2042 0 0 0 0 0 11.512 9.10355 12.005 10.636 0 10.3533 10.7843 11.3189 11.7884 11.5592 12.1104 10.7913 12.6787 12.7045 12.6045 11.7797 11.3071 11.8464 13.6013 13.4914 13.4877 P22392 NDKB_HUMAN Nucleoside diphosphate kinase B (NDK B) (NDP kinase B) (EC 2.7.4.6) (C-myc purine-binding transcription factor PUF) (Histidine protein kinase NDKB) (EC 2.7.13.3) (nm23-H2) NME2 NM23B Homo sapiens (Human) cell adhesion [GO:0007155]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of epidermis development [GO:0045682]; UTP biosynthetic process [GO:0006228] cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lamellipodium [GO:0030027]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774] ATP binding [GO:0005524]; DNA binding [GO:0003677]; G-quadruplex DNA binding [GO:0051880]; GDP binding [GO:0019003]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; transcription coactivator activity [GO:0003713] 0 18.165 GLVGEIIK 8.29016 10.4584 11.1974 0 0 0 11.5959 11.4107 11.2397 11.1743 0 11.1208 10.9736 11.3397 11.6079 12.6432 12.7903 12.36 0 0 0 0 0 0 12.2133 0 11.0841 P22413 ENPP1_HUMAN "Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (E-NPP 1) (Membrane component chromosome 6 surface marker 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) [Cleaved into: Ectonucleotide pyrophosphatase/phosphodiesterase family member 1, secreted form] [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (NPPase) (EC 3.6.1.9) (Nucleotide diphosphatase)]" ENPP1 M6S1 NPPS PC1 PDNP1 Homo sapiens (Human) 3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; ATP metabolic process [GO:0046034]; bone mineralization [GO:0030282]; cellular response to insulin stimulus [GO:0032869]; gene expression [GO:0010467]; generation of precursor metabolites and energy [GO:0006091]; immune response [GO:0006955]; inorganic diphosphate transport [GO:0030505]; intracellular phosphate ion homeostasis [GO:0030643]; melanocyte differentiation [GO:0030318]; negative regulation of bone mineralization [GO:0030502]; negative regulation of cell growth [GO:0030308]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of glucose import [GO:0046325]; negative regulation of glycogen biosynthetic process [GO:0045719]; negative regulation of hh target transcription factor activity [GO:1990787]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of protein autophosphorylation [GO:0031953]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; nucleoside triphosphate catabolic process [GO:0009143]; phosphate ion homeostasis [GO:0055062]; phosphate-containing compound metabolic process [GO:0006796]; regulation of bone mineralization [GO:0030500]; response to ATP [GO:0033198]; response to inorganic substance [GO:0010035]; sequestering of triglyceride [GO:0030730] basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886] "3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3'-phosphoadenosine 5'-phosphosulfate binding [GO:0050656]; ATP binding [GO:0005524]; ATP diphosphatase activity [GO:0047693]; calcium ion binding [GO:0005509]; cyclic-GMP-AMP hydrolase activity [GO:0106177]; dinucleotide phosphatase activity [GO:0004551]; exonuclease activity [GO:0004527]; GTP diphosphatase activity [GO:0036219]; insulin receptor binding [GO:0005158]; nucleic acid binding [GO:0003676]; nucleoside triphosphate diphosphatase activity [GO:0047429]; phosphatase activity [GO:0016791]; phosphodiesterase I activity [GO:0004528]; polysaccharide binding [GO:0030247]; protein homodimerization activity [GO:0042803]; scavenger receptor activity [GO:0005044]; UTP diphosphatase activity [GO:0036221]; zinc ion binding [GO:0008270]" 0.95742 -1.6532 EPVSDILK 0 0 0 10.1076 10.2794 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P22455 FGFR4_HUMAN Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334) FGFR4 JTK2 TKF Homo sapiens (Human) cell migration [GO:0016477]; cholesterol homeostasis [GO:0042632]; fibroblast growth factor receptor signaling pathway [GO:0008543]; glucose homeostasis [GO:0042593]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphate ion homeostasis [GO:0055062]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of proteolysis [GO:0045862]; protein autophosphorylation [GO:0046777]; regulation of bile acid biosynthetic process [GO:0070857]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of lipid metabolic process [GO:0019216]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; transport vesicle [GO:0030133] ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor receptor activity [GO:0005007]; heparin binding [GO:0008201] 0.93216 -1.2746 QFSLESGSSGKSSSSLVRGVR 0 0 0 9.1812 0 8.91139 0 0 0 0 0 0 0 0 0 10.6464 0 10.4301 0 0 0 9.56274 0 0 0 0 0 P22459 KCNA4_HUMAN Potassium voltage-gated channel subfamily A member 4 (HPCN2) (Voltage-gated K(+) channel HuKII) (Voltage-gated potassium channel HBK4) (Voltage-gated potassium channel HK1) (Voltage-gated potassium channel subunit Kv1.4) KCNA4 KCNA4L Homo sapiens (Human) potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of monoatomic ion transmembrane transport [GO:0034765] axon [GO:0030424]; axon initial segment [GO:0043194]; dendritic spine [GO:0043197]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076] delayed rectifier potassium channel activity [GO:0005251]; potassium ion binding [GO:0030955]; voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential [GO:0099508]; voltage-gated potassium channel activity [GO:0005249] 0.49706 0.61607 ALPENEFK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.9714 0 0 0 0 0 0 0 0 0 0 0 0 0 P22557 HEM0_HUMAN "5-aminolevulinate synthase, erythroid-specific, mitochondrial (ALAS-E) (EC 2.3.1.37) (5-aminolevulinic acid synthase 2) (Delta-ALA synthase 2) (Delta-aminolevulinate synthase 2)" ALAS2 ALASE ASB Homo sapiens (Human) erythrocyte development [GO:0048821]; erythrocyte differentiation [GO:0030218]; heme biosynthetic process [GO:0006783]; hemoglobin biosynthetic process [GO:0042541]; intracellular iron ion homeostasis [GO:0006879]; intracellular oxygen homeostasis [GO:0032364]; protoporphyrinogen IX biosynthetic process [GO:0006782]; response to hypoxia [GO:0001666] mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] 5-aminolevulinate synthase activity [GO:0003870]; pyridoxal phosphate binding [GO:0030170] 0.87093 0.03776 MVTAAMLLQCCPVLAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3773 0 0 0 0 0 0 0 0 P22570 ADRO_HUMAN "NADPH:adrenodoxin oxidoreductase, mitochondrial (AR) (Adrenodoxin reductase) (EC 1.18.1.6) (Ferredoxin--NADP(+) reductase) (Ferredoxin reductase)" FDXR ADXR Homo sapiens (Human) cholesterol metabolic process [GO:0008203]; generation of precursor metabolites and energy [GO:0006091]; steroid biosynthetic process [GO:0006694]; ubiquinone biosynthetic process [GO:0006744] mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH-adrenodoxin reductase activity [GO:0015039] 0.90683 -0.71783 EVPRPRK 0 0 0 0 10.0353 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P22612 KAPCG_HUMAN cAMP-dependent protein kinase catalytic subunit gamma (PKA C-gamma) (EC 2.7.11.11) PRKACG Homo sapiens (Human) high-density lipoprotein particle assembly [GO:0034380]; male gonad development [GO:0008584]; peptidyl-serine phosphorylation [GO:0018105]; protein kinase A signaling [GO:0010737]; renal water homeostasis [GO:0003091]; spermatogenesis [GO:0007283] cAMP-dependent protein kinase complex [GO:0005952]; ciliary base [GO:0097546]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] AMP-activated protein kinase activity [GO:0004679]; ATP binding [GO:0005524]; cAMP-dependent protein kinase activity [GO:0004691]; protein kinase A regulatory subunit binding [GO:0034237]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.91927 -0.90888 LSSDLKHLLR 0 0 12.2921 0 10.2794 0 0 11.9253 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P22626 ROA2_HUMAN Heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2/B1) HNRNPA2B1 HNRPA2B1 Homo sapiens (Human) "G-quadruplex DNA unwinding [GO:0044806]; miRNA transport [GO:1990428]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of telomerase RNA reverse transcriptase activity [GO:1905663]; positive regulation of telomere maintenance via telomere lengthening [GO:1904358]; primary miRNA processing [GO:0031053]; RNA transport [GO:0050658]" "Cajal body [GO:0015030]; catalytic step 2 spliceosome [GO:0071013]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]" G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; molecular condensate scaffold activity [GO:0140693]; mRNA 3'-UTR binding [GO:0003730]; N6-methyladenosine-containing RNA binding [GO:1990247]; pre-mRNA intronic binding [GO:0097157]; RNA binding [GO:0003723]; single-stranded telomeric DNA binding [GO:0043047] 0 39.598 ALSRQEMQEVQSSR 11.0852 11.2385 11.299 0 0 0 11.718 11.5155 11.6062 11.8862 11.9335 12.1628 9.17662 0 9.33755 0 10.8996 9.87209 11.118 10.8338 10.4613 11.3232 11.6541 12.0284 11.7948 11.1346 12.4793 P22670 RFX1_HUMAN MHC class II regulatory factor RFX1 (Enhancer factor C) (EF-C) (Regulatory factor X 1) (RFX) (Transcription factor RFX1) RFX1 Homo sapiens (Human) immune response [GO:0006955]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.95501 -1.5691 CEDRVVQR 0 0 0 0 8.89464 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P22674 CCNO_HUMAN Cyclin-O CCNO Homo sapiens (Human) cell division [GO:0051301]; cilium assembly [GO:0060271]; mitotic cell cycle [GO:0000278]; mitotic cell cycle phase transition [GO:0044772]; multi-ciliated epithelial cell differentiation [GO:1903251]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; response to xenobiotic stimulus [GO:0009410] centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleus [GO:0005634] cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538] 0.88408 -0.29658 QVEVHPPRVK 0 0 0 0 0 0 0 8.90968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P22676 CALB2_HUMAN Calretinin (CR) (29 kDa calbindin) CALB2 CAB29 Homo sapiens (Human) regulation of long-term synaptic potentiation [GO:1900271]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509] cytosol [GO:0005829]; dendrite [GO:0030425]; gap junction [GO:0005921]; nucleus [GO:0005634]; parallel fiber to Purkinje cell synapse [GO:0098688]; synapse [GO:0045202]; terminal bouton [GO:0043195] calcium ion binding [GO:0005509]; calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration [GO:0099534] 0.96705 -2.8386 DLYEKNK 0 0 0 0 0 0 0 0 0 0 0 9.12998 0 0 0 0 0 0 0 0 0 0 0 0 9.37271 0 0 P22735 TGM1_HUMAN Protein-glutamine gamma-glutamyltransferase K (EC 2.3.2.13) (Epidermal TGase) (Transglutaminase K) (TG(K)) (TGK) (TGase K) (Transglutaminase-1) (TGase-1) TGM1 KTG Homo sapiens (Human) cell envelope organization [GO:0043163]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; positive regulation of cell cycle [GO:0045787]; positive regulation of keratinocyte proliferation [GO:0010838]; protein modification process [GO:0036211] cornified envelope [GO:0001533]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886] identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810] 0.96943 -4.8958 EGMLVVNGVDLLSSR 0 0 0 0 0 0 0 0 0 9.48142 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P22748 CAH4_HUMAN Carbonic anhydrase 4 (EC 4.2.1.1) (Carbonate dehydratase IV) (Carbonic anhydrase IV) (CA-IV) CA4 Homo sapiens (Human) bicarbonate transport [GO:0015701] apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell surface [GO:0009986]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658] carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270] 0.88398 -0.055574 GSEHSLDGEHFAMEMHIVHEK 0 0 0 0 0 0 0 0 0 10.0662 0 10.1779 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P22749 GNLY_HUMAN Granulysin (Lymphokine LAG-2) (Protein NKG5) (T-cell activation protein 519) GNLY LAG2 NKG5 TLA519 Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; killing of cells of another organism [GO:0031640] extracellular region [GO:0005576]; extracellular space [GO:0005615]; phagocytic vesicle lumen [GO:0097013] 0.84962 0.16239 VTQGLVAGETAQQICEDLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.51203 0 P22888 LSHR_HUMAN Lutropin-choriogonadotropic hormone receptor (LH/CG-R) (Luteinizing hormone receptor) (LHR) (LSH-R) LHCGR LCGR LGR2 LHRHR Homo sapiens (Human) "activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; arachidonic acid secretion [GO:0050482]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to luteinizing hormone stimulus [GO:0071373]; central nervous system development [GO:0007417]; cognition [GO:0050890]; development of secondary male sexual characteristics [GO:0046544]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; hormone-mediated signaling pathway [GO:0009755]; luteinizing hormone signaling pathway [GO:0042700]; male genitalia development [GO:0030539]; male gonad development [GO:0008584]; ovarian follicle development [GO:0001541]; ovulation cycle process [GO:0022602]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of hormone biosynthetic process [GO:0046886]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; protein targeting to lysosome [GO:0006622]; regulation of steroid hormone biosynthetic process [GO:0090030]; response to xenobiotic stimulus [GO:0009410]; seminiferous tubule development [GO:0072520]; spermatogenesis [GO:0007283]; uterus development [GO:0060065]" centriolar satellite [GO:0034451]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; extracellular space [GO:0005615]; lysosome [GO:0005764]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] ATPase binding [GO:0051117]; choriogonadotropin hormone binding [GO:0038106]; choriogonadotropin hormone receptor activity [GO:0035472]; G protein-coupled peptide receptor activity [GO:0008528]; identical protein binding [GO:0042802]; luteinizing hormone receptor activity [GO:0004964]; peptide hormone binding [GO:0017046] 0.84972 0.11549 IYFAVRNPELMATNK 0 0 0 0 0 0 8.63836 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.92023 P22891 PROZ_HUMAN Vitamin K-dependent protein Z PROZ Homo sapiens (Human) blood coagulation [GO:0007596]; proteolysis [GO:0006508] endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796] calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252] 0.89882 -0.59197 ITHVHVHMR 0 0 0 0 0 0 0 0 0 0 0 0 9.4821 9.55624 0 0 11.044 0 0 11.827 0 0 0 0 0 0 0 P22894 MMP8_HUMAN Neutrophil collagenase (EC 3.4.24.34) (Matrix metalloproteinase-8) (MMP-8) (PMNL collagenase) (PMNL-CL) MMP8 CLG1 Homo sapiens (Human) collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor production [GO:0032760]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077] collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724] endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270] 0.96258 -2.1714 SKTYFFVNDQFWR 0 0 0 0 0 9.15393 0 0 0 0 0 0 9.10583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P22897 MRC1_HUMAN Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) MRC1 CLEC13D CLEC13DL MRC1L1 Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] cell surface [GO:0009986]; endosome membrane [GO:0010008]; plasma membrane [GO:0005886] cargo receptor activity [GO:0038024]; mannose binding [GO:0005537]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618] 0.94547 -1.3414 SACVYLDLDGYWK 0 10.8653 0 10.457 0 0 9.51092 12.051 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P23025 XPA_HUMAN DNA repair protein complementing XP-A cells (Xeroderma pigmentosum group A-complementing protein) XPA XPAC Homo sapiens (Human) "base-excision repair [GO:0006284]; DNA repair [GO:0006281]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair involved in interstrand cross-link repair [GO:1901255]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; protein localization to nucleus [GO:0034504]; UV protection [GO:0009650]; UV-damage excision repair [GO:0070914]" intercellular bridge [GO:0045171]; nucleoplasm [GO:0005654]; nucleotide-excision repair factor 1 complex [GO:0000110]; nucleus [GO:0005634] damaged DNA binding [GO:0003684]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; sequence-specific double-stranded DNA binding [GO:1990837] 0.8638 0.084132 NPHHSQWGDMKLYLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.3726 0 P23109 AMPD1_HUMAN AMP deaminase 1 (EC 3.5.4.6) (AMP deaminase isoform M) (Myoadenylate deaminase) AMPD1 Homo sapiens (Human) AMP metabolic process [GO:0046033]; GMP salvage [GO:0032263]; IMP biosynthetic process [GO:0006188]; IMP salvage [GO:0032264] cytosol [GO:0005829] AMP deaminase activity [GO:0003876]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872] 0.92249 -1.1202 EVGADLVEAK 0 0 0 0 0 0 0 11.1232 10.3703 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P23141 EST1_HUMAN Liver carboxylesterase 1 (Acyl-coenzyme A:cholesterol acyltransferase) (ACAT) (Brain carboxylesterase hBr1) (Carboxylesterase 1) (CE-1) (hCE-1) (EC 3.1.1.1) (Cholesteryl ester hydrolase) (CEH) (EC 3.1.1.13) (Cocaine carboxylesterase) (Egasyn) (HMSE) (Methylumbelliferyl-acetate deacetylase 1) (EC 3.1.1.56) (Monocyte/macrophage serine esterase) (Retinyl ester hydrolase) (REH) (Serine esterase 1) (Triacylglycerol hydrolase) (TGH) CES1 CES2 SES1 Homo sapiens (Human) cellular response to cholesterol [GO:0071397]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; negative regulation of cholesterol storage [GO:0010887]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cholesterol metabolic process [GO:0090205]; regulation of bile acid biosynthetic process [GO:0070857]; regulation of bile acid secretion [GO:0120188]; response to toxic substance [GO:0009636]; reverse cholesterol transport [GO:0043691] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; lipid droplet [GO:0005811] carboxylesterase activity [GO:0106435]; carboxylic ester hydrolase activity [GO:0052689]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771] 0.63074 0.39856 AVEKPPQTEHIEL 0 0 0 0 0 0 0 0 9.8901 0 0 0 9.41663 0 0 0 0 0 0 0 0 10.3263 0 0 0 0 0 P23142 FBLN1_HUMAN Fibulin-1 (FIBL-1) FBLN1 PP213 Homo sapiens (Human) "blood coagulation, fibrin clot formation [GO:0072378]; embryo implantation [GO:0007566]; extracellular matrix organization [GO:0030198]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; negative regulation of transformation of host cell by virus [GO:1904188]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]" basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; elastic fiber [GO:0071953]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] calcium ion binding [GO:0005509]; extracellular matrix structural constituent [GO:0005201]; fibrinogen binding [GO:0070051]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protein-containing complex binding [GO:0044877] 0.9152 -0.79606 DSFDIIKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0935 0 0 0 0 0 0 0 0 0 P23193 TCEA1_HUMAN Transcription elongation factor A protein 1 (Transcription elongation factor S-II protein 1) (Transcription elongation factor TFIIS.o) TCEA1 GTF2S TFIIS Homo sapiens (Human) DNA-templated transcription [GO:0006351]; positive regulation of transcription by RNA polymerase II [GO:0045944]; transcription by RNA polymerase II [GO:0006366]; transcription elongation by RNA polymerase II [GO:0006368] nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor TFIID complex [GO:0005669] DNA binding [GO:0003677]; zinc ion binding [GO:0008270] 0.92019 -0.9186 DTYVSSFPR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7044 0 0 0 0 0 0 0 0 0 0 0 0 0 P23219 PGH1_HUMAN Prostaglandin G/H synthase 1 (EC 1.14.99.1) (Cyclooxygenase-1) (COX-1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1) (Prostaglandin-endoperoxide synthase 1) PTGS1 COX1 Homo sapiens (Human) cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; response to oxidative stress [GO:0006979] cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; neuron projection [GO:0043005]; photoreceptor outer segment [GO:0001750] "heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]" 0.9144 -0.76275 KQLPDAQLLARR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.49019 0 0 0 0 0 0 0 0 0 0 0 0 0 P23229 ITA6_HUMAN Integrin alpha-6 (CD49 antigen-like family member F) (VLA-6) (CD antigen CD49f) [Cleaved into: Integrin alpha-6 heavy chain; Integrin alpha-6 light chain; Processed integrin alpha-6 (Alpha6p)] ITGA6 Homo sapiens (Human) cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; cell-substrate junction assembly [GO:0007044]; ectodermal cell differentiation [GO:0010668]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; nail development [GO:0035878]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transcription by RNA polymerase II [GO:0045944]; skin morphogenesis [GO:0043589] cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886] cadherin binding [GO:0045296]; insulin-like growth factor I binding [GO:0031994]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; neuregulin binding [GO:0038132] 0.95958 -1.9225 KEEREIK 0 0 0 0 0 0 10.1929 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P23246 SFPQ_HUMAN "Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)" SFPQ PSF Homo sapiens (Human) "activation of innate immune response [GO:0002218]; alternative mRNA splicing, via spliceosome [GO:0000380]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; innate immune response [GO:0045087]; mRNA processing [GO:0006397]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-templated transcription [GO:0006355]; rhythmic process [GO:0048511]; RNA splicing [GO:0008380]" chromatin [GO:0000785]; cytosol [GO:0005829]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; RNA polymerase II transcription regulator complex [GO:0090575] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; histone deacetylase binding [GO:0042826]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; transcription cis-regulatory region binding [GO:0000976] 0.0082873 2.1948 EEYEGPNK 9.35125 0 0 0 0 0 8.93189 0 11.664 9.89323 12.0558 0 0 0 0 9.68071 0 0 10.5255 0 0 0 0 0 10.1326 10.3147 0 P23284 PPIB_HUMAN Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (CYP-S1) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP) PPIB CYPB Homo sapiens (Human) bone development [GO:0060348]; chaperone-mediated protein folding [GO:0061077]; neutrophil chemotaxis [GO:0030593]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation by host of viral process [GO:0044794]; positive regulation of multicellular organism growth [GO:0040018]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790] cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; RNA polymerase binding [GO:0070063]; unfolded protein binding [GO:0051082] 0 24.726 DTNGSQFFITTVK 10.45 9.50144 10.5078 0 0 0 10.1966 11.509 11.809 8.98996 9.6035 10.1459 0 10.0739 0 10.6398 0 0 12.271 0 0 9.61408 0 9.56442 0 10.3078 0 P23327 SRCH_HUMAN Sarcoplasmic reticulum histidine-rich calcium-binding protein HRC HCP Homo sapiens (Human) muscle contraction [GO:0006936]; positive regulation of heart contraction [GO:0045823]; positive regulation of heart rate [GO:0010460]; positive regulation of relaxation of cardiac muscle [GO:1901899]; regulation of calcium ion transmembrane transport [GO:1903169]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of heart rate [GO:0002027]; regulation of peptidyl-serine phosphorylation [GO:0033135]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314] endoplasmic reticulum lumen [GO:0005788]; sarcoplasmic reticulum lumen [GO:0033018]; sarcoplasmic reticulum membrane [GO:0033017]; Z disc [GO:0030018] ATPase binding [GO:0051117]; calcium ion binding [GO:0005509]; transmembrane transporter binding [GO:0044325] 0.88462 -0.24853 GDGLGFRNR 0 10.3741 0 0 0 0 0 0 0 9.61152 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P23352 KALM_HUMAN Anosmin-1 (Adhesion molecule-like X-linked) (Kallmann syndrome protein) ANOS1 ADMLX KAL KAL1 KALIG1 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155]; chemotaxis [GO:0006935]; negative regulation of peptidase activity [GO:0010466]; neuron differentiation [GO:0030182] cell surface [GO:0009986]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; serine-type endopeptidase inhibitor activity [GO:0004867] 0.92512 -0.97678 HPHHYKPSPERY 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4669 0 11.7074 0 0 0 0 0 0 0 0 0 0 P23368 MAOM_HUMAN "NAD-dependent malic enzyme, mitochondrial (NAD-ME) (EC 1.1.1.38) (Malic enzyme 2)" ME2 Homo sapiens (Human) malate metabolic process [GO:0006108]; pyruvate metabolic process [GO:0006090]; regulation of NADP metabolic process [GO:1902031] intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] electron transfer activity [GO:0009055]; malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; malate dehydrogenase (decarboxylating) (NADP+) activity [GO:0004473]; malic enzyme activity [GO:0004470]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; oxaloacetate decarboxylase activity [GO:0008948] 0.91352 -0.7567 YIYIMGIQERNEK 0 0 10.4829 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P23378 GCSP_HUMAN "Glycine dehydrogenase (decarboxylating), mitochondrial (EC 1.4.4.2) (Glycine cleavage system P protein) (Glycine decarboxylase) (Glycine dehydrogenase (aminomethyl-transferring))" GLDC GCSP Homo sapiens (Human) cellular response to leukemia inhibitory factor [GO:1990830]; glycine catabolic process [GO:0006546]; glycine decarboxylation via glycine cleavage system [GO:0019464]; response to lipoic acid [GO:1903442]; response to methylamine [GO:0036255] glycine cleavage complex [GO:0005960]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] electron transfer activity [GO:0009055]; glycine binding [GO:0016594]; glycine dehydrogenase (decarboxylating) activity [GO:0004375]; lyase activity [GO:0016829]; protein homodimerization activity [GO:0042803]; pyridoxal binding [GO:0070280]; pyridoxal phosphate binding [GO:0030170] 0.96704 -2.8334 LGRGVGGGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.16035 0 0 P23381 SYWC_HUMAN "Tryptophan--tRNA ligase, cytoplasmic (EC 6.1.1.2) (Interferon-induced protein 53) (IFP53) (Tryptophanyl-tRNA synthetase) (TrpRS) (hWRS) [Cleaved into: T1-TrpRS; T2-TrpRS]" WARS1 IFI53 WARS WRS Homo sapiens (Human) angiogenesis [GO:0001525]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of gene expression [GO:0010628]; positive regulation of protein-containing complex assembly [GO:0031334]; regulation of angiogenesis [GO:0045765]; translation [GO:0006412]; tryptophanyl-tRNA aminoacylation [GO:0006436] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] ATP binding [GO:0005524]; kinase inhibitor activity [GO:0019210]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; tryptophan-tRNA ligase activity [GO:0004830] 0.55996 0.54074 DIIACGFDINK 0 10.9071 0 0 0 0 0 0 0 0 0 0 0 0 11.1862 0 0 10.4862 0 0 0 0 0 0 0 0 0 P23396 RS3_HUMAN Small ribosomal subunit protein uS3 (40S ribosomal protein S3) (EC 4.2.99.18) RPS3 OK/SW-cl.26 Homo sapiens (Human) apoptotic process [GO:0006915]; cell division [GO:0051301]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to reactive oxygen species [GO:0034614]; cellular response to tumor necrosis factor [GO:0071356]; chromosome segregation [GO:0007059]; cytoplasmic translation [GO:0002181]; DNA damage response [GO:0006974]; DNA repair [GO:0006281]; negative regulation of DNA repair [GO:0045738]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of translation [GO:0017148]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of base-excision repair [GO:1905053]; positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:2001272]; positive regulation of DNA N-glycosylase activity [GO:1902546]; positive regulation of DNA repair [GO:0045739]; positive regulation of endodeoxyribonuclease activity [GO:0032079]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902231]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein-containing complex assembly [GO:0031334]; positive regulation of T cell receptor signaling pathway [GO:0050862]; regulation of apoptotic process [GO:0042981]; response to TNF agonist [GO:0061481]; spindle assembly [GO:0051225]; translation [GO:0006412]; translational initiation [GO:0006413] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitotic spindle [GO:0072686]; NF-kappaB complex [GO:0071159]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; polysome [GO:0005844]; postsynaptic density [GO:0014069]; ribonucleoprotein complex [GO:1990904]; ribosome [GO:0005840]; ruffle membrane [GO:0032587] class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA endonuclease activity [GO:0004520]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-binding transcription factor binding [GO:0140297]; enzyme binding [GO:0019899]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; iron-sulfur cluster binding [GO:0051536]; kinase binding [GO:0019900]; microtubule binding [GO:0008017]; mRNA binding [GO:0003729]; oxidized purine DNA binding [GO:0032357]; oxidized pyrimidine DNA binding [GO:0032358]; protein kinase A binding [GO:0051018]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; small ribosomal subunit rRNA binding [GO:0070181]; structural constituent of ribosome [GO:0003735]; supercoiled DNA binding [GO:0097100]; tubulin binding [GO:0015631]; ubiquitin-like protein conjugating enzyme binding [GO:0044390] 0 5.8657 AELNEFLTR 8.9043 11.0389 8.76308 0 0 0 11.665 11.6488 11.6343 0 0 0 0 0 0 9.10622 9.06722 0 0 9.32242 7.84643 9.07036 0 10.4234 9.79766 11.763 0 P23435 CBLN1_HUMAN Cerebellin-1 (Precerebellin) [Cleaved into: Cerebellin (CER); [des-Ser1]-cerebellin] CBLN1 Homo sapiens (Human) cerebellar granule cell differentiation [GO:0021707]; chemical synaptic transmission [GO:0007268]; establishment of localization in cell [GO:0051649]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; maintenance of synapse structure [GO:0099558]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of inhibitory synapse assembly [GO:1905703]; nervous system development [GO:0007399]; positive regulation of long-term synaptic depression [GO:1900454]; positive regulation of synapse assembly [GO:0051965]; protein secretion [GO:0009306]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]; synapse assembly [GO:0007416]; synapse organization [GO:0050808] collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; glutamatergic synapse [GO:0098978]; parallel fiber to Purkinje cell synapse [GO:0098688]; postsynaptic membrane [GO:0045211]; synaptic cleft [GO:0043083] identical protein binding [GO:0042802] 0.049041 1.4442 STFIAPRKGIYSFNFHVVK 0 0 0 0 0 0 10.6524 10.4657 10.6626 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.59803 0 0 P23443 KS6B1_HUMAN Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA) RPS6KB1 STK14A Homo sapiens (Human) aging [GO:0007568]; apoptotic process [GO:0006915]; behavioral fear response [GO:0001662]; cell migration [GO:0016477]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to growth factor stimulus [GO:0071363]; cellular response to insulin stimulus [GO:0032869]; cellular response to type II interferon [GO:0071346]; G1/S transition of mitotic cell cycle [GO:0000082]; germ cell development [GO:0007281]; long-chain fatty acid import into cell [GO:0044539]; long-term memory [GO:0007616]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; peptidyl-serine phosphorylation [GO:0018105]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of skeletal muscle tissue growth [GO:0048633]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of translation [GO:0045727]; positive regulation of translational initiation [GO:0045948]; protein kinase B signaling [GO:0043491]; regulation of glucose import [GO:0046324]; response to electrical stimulus involved in regulation of muscle adaptation [GO:0014878]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to leucine [GO:0043201]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to nutrient [GO:0007584]; response to nutrient levels [GO:0031667]; response to testosterone [GO:0033574]; response to toxic substance [GO:0009636]; response to tumor necrosis factor [GO:0034612]; response to wounding [GO:0009611]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165]; skeletal muscle atrophy [GO:0014732]; skeletal muscle contraction [GO:0003009]; TOR signaling [GO:0031929] cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794] ATP binding [GO:0005524]; identical protein binding [GO:0042802]; PDZ domain binding [GO:0030165]; peptide binding [GO:0042277]; protein kinase activity [GO:0004672]; protein phosphatase 2A binding [GO:0051721]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; ribosomal protein S6 kinase activity [GO:0004711] 0.96756 -2.3467 EKFSFEPK 0 0 0 0 0 8.94553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.64622 0 0 0 P23458 JAK1_HUMAN Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1) JAK1 JAK1A JAK1B Homo sapiens (Human) cell differentiation [GO:0030154]; cellular response to virus [GO:0098586]; cytokine-mediated signaling pathway [GO:0019221]; interleukin-11-mediated signaling pathway [GO:0038154]; interleukin-15-mediated signaling pathway [GO:0035723]; interleukin-2-mediated signaling pathway [GO:0038110]; interleukin-4-mediated signaling pathway [GO:0035771]; interleukin-6-mediated signaling pathway [GO:0070102]; interleukin-9-mediated signaling pathway [GO:0038113]; intracellular signal transduction [GO:0035556]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of sprouting angiogenesis [GO:1903672]; protein localization to cell-cell junction [GO:0150105]; protein phosphorylation [GO:0006468]; receptor signaling pathway via JAK-STAT [GO:0007259]; response to antibiotic [GO:0046677]; T-helper 17 cell lineage commitment [GO:0072540]; type I interferon-mediated signaling pathway [GO:0060337]; type II interferon-mediated signaling pathway [GO:0060333]; type III interferon-mediated signaling pathway [GO:0038196]; tyrosine phosphorylation of STAT protein [GO:0007260] cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endosome [GO:0005768]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; extrinsic component of plasma membrane [GO:0019897]; focal adhesion [GO:0005925]; nucleus [GO:0005634] ATP binding [GO:0005524]; CCR5 chemokine receptor binding [GO:0031730]; cytokine receptor binding [GO:0005126]; growth hormone receptor binding [GO:0005131]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transcription regulator activator activity [GO:0140537]; ubiquitin protein ligase binding [GO:0031625] 0.96844 -3.6033 ISPLCHNLFALYDENTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.93481 0 9.76703 9.9884 0 0 0 0 9.78973 0 0 P23467 PTPRB_HUMAN Receptor-type tyrosine-protein phosphatase beta (Protein-tyrosine phosphatase beta) (R-PTP-beta) (EC 3.1.3.48) (Vascular endothelial protein tyrosine phosphatase) (VE-PTP) PTPRB PTPB Homo sapiens (Human) angiogenesis [GO:0001525]; dephosphorylation [GO:0016311]; glial cell migration [GO:0008347]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; phosphate-containing compound metabolic process [GO:0006796]; protein dephosphorylation [GO:0006470] plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821] cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001] 0.91299 -0.75588 NKNNFIQTK 9.3353 0 0 0 0 0 0 0 0 0 9.77563 10.3185 0 0 0 0 0 0 9.39643 0 0 0 0 0 0 0 0 P23468 PTPRD_HUMAN Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) PTPRD Homo sapiens (Human) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; Schaffer collateral - CA1 synapse [GO:0098685] cell adhesion molecule binding [GO:0050839]; signaling receptor binding [GO:0005102]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001] 0.84086 0.17997 CDQYWPSR 0 0 0 0 0 0 0 0 0 10.8721 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.27487 8.99839 P23470 PTPRG_HUMAN Receptor-type tyrosine-protein phosphatase gamma (Protein-tyrosine phosphatase gamma) (R-PTP-gamma) (EC 3.1.3.48) PTPRG PTPG Homo sapiens (Human) brain development [GO:0007420]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuron projection development [GO:0010977]; protein dephosphorylation [GO:0006470]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] identical protein binding [GO:0042802]; protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001] 0.9694 -5.6374 GQKGNPK 9.56811 9.52138 9.38135 0 0 0 10.2124 10.3338 10.2819 9.58148 10.0342 10.7009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P23471 PTPRZ_HUMAN Receptor-type tyrosine-protein phosphatase zeta (R-PTP-zeta) (EC 3.1.3.48) (Protein-tyrosine phosphatase receptor type Z polypeptide 1) (Protein-tyrosine phosphatase receptor type Z polypeptide 2) (R-PTP-zeta-2) PTPRZ1 HTPZP2 PTPRZ PTPRZ2 PTPZ Homo sapiens (Human) axonogenesis [GO:0007409]; central nervous system development [GO:0007417]; hematopoietic progenitor cell differentiation [GO:0002244]; learning or memory [GO:0007611]; negative regulation of neuron apoptotic process [GO:0043524]; oligodendrocyte differentiation [GO:0048709]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of oligodendrocyte differentiation [GO:0048714]; protein dephosphorylation [GO:0006470]; regulation of myelination [GO:0031641]; regulation of oligodendrocyte progenitor proliferation [GO:0070445] extracellular region [GO:0005576]; perineuronal net [GO:0072534]; plasma membrane [GO:0005886]; synapse [GO:0045202] integrin binding [GO:0005178]; protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001] 0.88781 -0.39726 AYIAAQGPLK 0 0 0 0 0 0 0 0 0 9.12407 10.6376 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7127 0 0 P23508 CRCM_HUMAN Colorectal mutant cancer protein (Protein MCC) MCC Homo sapiens (Human) establishment of protein localization [GO:0045184]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial cell proliferation [GO:0050680]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055] cytoplasm [GO:0005737]; cytosol [GO:0005829]; lamellipodium [GO:0030027]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] signaling receptor activity [GO:0038023] 0.96994 -4.3515 KKSSCSLSVAEVDK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.09945 0 0 0 0 0 10.6421 0 0 0 0 0 0 0 P23515 OMGP_HUMAN Oligodendrocyte-myelin glycoprotein OMG OMGP Homo sapiens (Human) cell adhesion [GO:0007155]; neuron projection regeneration [GO:0031102] plasma membrane [GO:0005886] 0.91472 -0.81654 EETTTNVK 0 0 0 9.53327 0 0 0 8.8069 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P23526 SAHH_HUMAN Adenosylhomocysteinase (AdoHcyase) (EC 3.13.2.1) (S-adenosyl-L-homocysteine hydrolase) AHCY SAHH Homo sapiens (Human) one-carbon metabolic process [GO:0006730]; S-adenosylmethionine cycle [GO:0033353] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; melanosome [GO:0042470] adenosylhomocysteinase activity [GO:0004013] 0 16.974 AGIPVYAWK 8.98874 9.03568 9.82101 0 0 0 10.3917 10.6744 11.1064 9.45325 0 9.43475 0 0 0 0 0 0 10.5101 9.87494 0 9.78067 0 9.51233 11.4531 12.5085 11.7296 P23528 COF1_HUMAN "Cofilin-1 (18 kDa phosphoprotein) (p18) (Cofilin, non-muscle isoform)" CFL1 CFL Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament depolymerization [GO:0030042]; actin filament fragmentation [GO:0030043]; actin filament severing [GO:0051014]; cytoskeleton organization [GO:0007010]; establishment of spindle localization [GO:0051293]; mitotic cytokinesis [GO:0000281]; negative regulation of apoptotic process [GO:0043066]; positive regulation by host of viral process [GO:0044794]; positive regulation of embryonic development [GO:0040019]; regulation of cell morphogenesis [GO:0022604]; regulation of dendritic spine morphogenesis [GO:0061001]; response to virus [GO:0009615]; Rho protein signal transduction [GO:0007266] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane [GO:0016020]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]; ruffle membrane [GO:0032587]; vesicle [GO:0031982] actin filament binding [GO:0051015] 0 47.58 ASGVAVSDGVIK 11.3365 11.3709 10.2138 0 0 0 10.8017 10.678 11.7625 12.1753 12.2948 12.2199 11.6189 11.667 12.0724 11.9361 12.0484 11.9663 12.3801 12.2289 12.411 11.8171 12.9162 12.673 14.1028 13.3635 13.1812 P23560 BDNF_HUMAN Brain-derived neurotrophic factor (BDNF) (Abrineurin) [Cleaved into: BDNF precursor form (ProBDNF)] BDNF Homo sapiens (Human) axon guidance [GO:0007411]; brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; collateral sprouting [GO:0048668]; memory [GO:0007613]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; nerve growth factor signaling pathway [GO:0038180]; nervous system development [GO:0007399]; neuron projection morphogenesis [GO:0048812]; positive regulation of brain-derived neurotrophic factor receptor signaling pathway [GO:0031550]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of receptor binding [GO:1900122]; positive regulation of synapse assembly [GO:0051965]; regulation of neuron differentiation [GO:0045664]; regulation of protein localization to cell surface [GO:2000008]; synapse assembly [GO:0007416]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] cytoplasm [GO:0005737]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; perinuclear region of cytoplasm [GO:0048471]; synaptic vesicle [GO:0008021] growth factor activity [GO:0008083]; nerve growth factor receptor binding [GO:0005163] 0.94742 -1.3546 VPVSKGQLKQYFYETK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.333 0 0 P23582 ANFC_HUMAN C-type natriuretic peptide [Cleaved into: CNP-22; CNP-29; CNP-53] NPPC CNP2 Homo sapiens (Human) angiogenesis [GO:0001525]; blood vessel diameter maintenance [GO:0097746]; blood vessel remodeling [GO:0001974]; c-di-GMP signaling [GO:0061939]; cellular response to glycoprotein [GO:1904588]; cGMP biosynthetic process [GO:0006182]; cGMP-mediated signaling [GO:0019934]; chromosome organization [GO:0051276]; cumulus cell differentiation [GO:0001549]; gastric emptying [GO:0035483]; growth plate cartilage chondrocyte differentiation [GO:0003418]; growth plate cartilage chondrocyte proliferation [GO:0003419]; intracellular calcium ion homeostasis [GO:0006874]; meiotic cell cycle process involved in oocyte maturation [GO:1903537]; multicellular organismal locomotion [GO:0071965]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of DNA biosynthetic process [GO:2000279]; negative regulation of meiotic cell cycle [GO:0051447]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oocyte maturation [GO:1900194]; ossification [GO:0001503]; positive regulation of cGMP-mediated signaling [GO:0010753]; positive regulation of osteoblast differentiation [GO:0045669]; post-embryonic development [GO:0009791]; protein folding [GO:0006457]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of multicellular organism growth [GO:0040014]; regulation of smooth muscle cell proliferation [GO:0048660]; response to axon injury [GO:0048678]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to ischemia [GO:0002931]; response to oxygen-glucose deprivation [GO:0090649]; response to xenobiotic stimulus [GO:0009410] extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141] hormone activity [GO:0005179]; hormone receptor binding [GO:0051427]; signaling receptor binding [GO:0005102] 0.50772 0.60646 TPPAEELAEPQAAGGGQKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.56786 0 0 0 0 0 0 0 P23588 IF4B_HUMAN Eukaryotic translation initiation factor 4B (eIF-4B) EIF4B Homo sapiens (Human) regulation of translational initiation [GO:0006446] cytosol [GO:0005829]; eukaryotic translation initiation factor 4F complex [GO:0016281] RNA binding [GO:0003723]; translation initiation factor activity [GO:0003743] 0.96439 -2.2793 DDYSRDDYR 0 10.0307 9.57204 0 0 0 8.87584 0 8.13904 8.62374 9.87492 9.67485 0 0 0 8.88756 0 0 8.71908 0 8.5635 0 0 0 0 0 0 P23634 AT2B4_HUMAN Plasma membrane calcium-transporting ATPase 4 (PMCA4) (EC 7.2.2.10) (Matrix-remodeling-associated protein 1) (Plasma membrane calcium ATPase isoform 4) (Plasma membrane calcium pump isoform 4) ATP2B4 ATP2B2 MXRA1 Homo sapiens (Human) calcium ion export [GO:1901660]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; cellular response to acetylcholine [GO:1905145]; cellular response to epinephrine stimulus [GO:0071872]; flagellated sperm motility [GO:0030317]; hippocampus development [GO:0021766]; intracellular calcium ion homeostasis [GO:0006874]; monoatomic ion transmembrane transport [GO:0034220]; negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process [GO:0140199]; negative regulation of angiogenesis [GO:0016525]; negative regulation of arginine catabolic process [GO:1900082]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cardiac muscle hypertrophy in response to stress [GO:1903243]; negative regulation of cellular response to vascular endothelial growth factor stimulus [GO:1902548]; negative regulation of citrulline biosynthetic process [GO:1903249]; negative regulation of gene expression [GO:0010629]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric oxide mediated signal transduction [GO:0010751]; negative regulation of nitric-oxide synthase activity [GO:0051001]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of the force of heart contraction [GO:0098736]; neural retina development [GO:0003407]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of cardiac conduction [GO:1903779]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of transcription by RNA polymerase II [GO:0006357]; response to hydrostatic pressure [GO:0051599]; spermatogenesis [GO:0007283]; transport across blood-brain barrier [GO:0150104]; urinary bladder smooth muscle contraction [GO:0014832] basolateral plasma membrane [GO:0016323]; caveola [GO:0005901]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; presynaptic active zone membrane [GO:0048787]; protein-containing complex [GO:0032991]; sperm flagellum [GO:0036126]; sperm principal piece [GO:0097228]; T-tubule [GO:0030315]; Z disc [GO:0030018] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; calcium ion transmembrane transporter activity [GO:0015085]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase inhibitor activity [GO:0036487]; P-type calcium transporter activity [GO:0005388]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; protein phosphatase 2B binding [GO:0030346]; scaffold protein binding [GO:0097110]; sodium channel regulator activity [GO:0017080] 0.84926 0.15624 GQILWFR 0 0 0 0 0 0 0 10.6753 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P23677 IP3KA_HUMAN "Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase A) (IP3 3-kinase A) (IP3K A) (InsP 3-kinase A)" ITPKA Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cellular response to calcium ion [GO:0071277]; dendritic spine maintenance [GO:0097062]; inositol metabolic process [GO:0006020]; inositol phosphate biosynthetic process [GO:0032958]; modification of postsynaptic actin cytoskeleton [GO:0098885]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; phosphorylation [GO:0016310]; positive regulation of dendritic spine morphogenesis [GO:0061003]; regulation of synaptic plasticity [GO:0048167]; response to calcium ion [GO:0051592]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; nucleus [GO:0005634]; postsynaptic actin cytoskeleton [GO:0098871] "ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; inositol tetrakisphosphate kinase activity [GO:0051765]; inositol-1,4,5-trisphosphate 3-kinase activity [GO:0008440]; small GTPase binding [GO:0031267]" 0.86993 0.058281 TTPLPDGQILDHR 0 0 10.1642 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P23743 DGKA_HUMAN Diacylglycerol kinase alpha (DAG kinase alpha) (EC 2.7.1.107) (80 kDa diacylglycerol kinase) (Diglyceride kinase alpha) (DGK-alpha) DGKA DAGK DAGK1 Homo sapiens (Human) diacylglycerol metabolic process [GO:0046339]; glycerolipid metabolic process [GO:0046486]; intracellular signal transduction [GO:0035556]; lipid phosphorylation [GO:0046834]; phosphatidic acid biosynthetic process [GO:0006654]; platelet activation [GO:0030168]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205] cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; diacylglycerol kinase activity [GO:0004143]; kinase activity [GO:0016301]; lipid binding [GO:0008289]; phospholipid binding [GO:0005543] 0.95497 -1.5674 DIGVQSHVWVRGGCESGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3225 0 P23786 CPT2_HUMAN "Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (CPT II)" CPT2 CPT1 Homo sapiens (Human) carnitine metabolic process [GO:0009437]; carnitine shuttle [GO:0006853]; fatty acid beta-oxidation [GO:0006635]; in utero embryonic development [GO:0001701]; long-chain fatty acid metabolic process [GO:0001676]; positive regulation of cold-induced thermogenesis [GO:0120162] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] acyltransferase activity [GO:0016746]; carnitine O-octanoyltransferase activity [GO:0008458]; carnitine O-palmitoyltransferase activity [GO:0004095] 0.96953 -3.0518 ALEDMFDALEGKSIKS 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.93236 0 11.8202 0 0 10.137 0 0 0 0 0 0 P23919 KTHY_HUMAN Thymidylate kinase (EC 2.7.4.9) (dTMP kinase) DTYMK CDC8 TMPK TYMK Homo sapiens (Human) cellular response to growth factor stimulus [GO:0071363]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; phosphorylation [GO:0016310]; thymidine biosynthetic process [GO:0046105] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634] ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041] 0.9254 -1.1781 ALRCFHQLMK 0 0 0 0 0 0 0 0 0 8.46984 0 0 0 0 0 0 0 0 0 0 0 9.93356 0 0 0 0 0 P23975 SC6A2_HUMAN Sodium-dependent noradrenaline transporter (Norepinephrine transporter) (NET) (Solute carrier family 6 member 2) SLC6A2 NAT1 NET1 SLC6A5 Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; dopamine uptake involved in synaptic transmission [GO:0051583]; monoamine transport [GO:0015844]; neuron cellular homeostasis [GO:0070050]; neurotransmitter transport [GO:0006836]; norepinephrine transport [GO:0015874]; norepinephrine uptake [GO:0051620]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sodium ion transmembrane transport [GO:0035725] cell surface [GO:0009986]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734] actin binding [GO:0003779]; alpha-tubulin binding [GO:0043014]; beta-tubulin binding [GO:0048487]; dopamine:sodium symporter activity [GO:0005330]; metal ion binding [GO:0046872]; monoamine transmembrane transporter activity [GO:0008504]; neurotransmitter transmembrane transporter activity [GO:0005326]; neurotransmitter:sodium symporter activity [GO:0005328]; norepinephrine:sodium symporter activity [GO:0005334] 0.85789 0.10086 DGDAQPRETWGK 0 0 0 8.93631 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P24001 IL32_HUMAN Interleukin-32 (IL-32) (Natural killer cells protein 4) (Tumor necrosis factor alpha-inducing factor) IL32 NK4 TAIF Homo sapiens (Human) cell adhesion [GO:0007155]; defense response [GO:0006952]; immune response [GO:0006955]; negative regulation of viral life cycle [GO:1903901]; positive regulation of gene expression [GO:0010628]; positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1905636]; positive regulation of type III interferon production [GO:0034346] cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020] cytokine activity [GO:0005125] 0.91657 -0.84398 DKDPALWCQLCLSSQHQAIER 12.5006 12.1911 0 11.6886 11.5887 11.5501 12.5435 12.202 0 0 0 0 0 11.338 0 11.6088 0 0 0 0 0 0 0 0 0 0 0 P24043 LAMA2_HUMAN Laminin subunit alpha-2 (Laminin M chain) (Laminin-12 subunit alpha) (Laminin-2 subunit alpha) (Laminin-4 subunit alpha) (Merosin heavy chain) LAMA2 LAMM Homo sapiens (Human) "axon guidance [GO:0007411]; cell adhesion [GO:0007155]; maintenance of blood-brain barrier [GO:0035633]; muscle organ development [GO:0007517]; positive regulation of cell adhesion [GO:0045785]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of basement membrane organization [GO:0110011]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]" basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; neuromuscular junction [GO:0031594]; protein complex involved in cell-matrix adhesion [GO:0098637]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083] signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198] 0.96824 -3.6379 DDEVICTSFYSK 0 0 8.98128 0 0 0 0 0 0 9.1693 0 0 0 0 0 0 0 0 0 0 0 12.3493 9.26718 0 0 0 0 P24298 ALAT1_HUMAN Alanine aminotransferase 1 (ALT1) (EC 2.6.1.2) (Glutamate pyruvate transaminase 1) (GPT 1) (Glutamic--alanine transaminase 1) (Glutamic--pyruvic transaminase 1) GPT AAT1 GPT1 Homo sapiens (Human) biosynthetic process [GO:0009058]; cellular response to insulin stimulus [GO:0032869]; L-alanine catabolic process [GO:0042853]; positive regulation of gluconeogenesis [GO:0045722]; response to starvation [GO:0042594] cytosol [GO:0005829]; extracellular exosome [GO:0070062] L-alanine:2-oxoglutarate aminotransferase activity [GO:0004021]; pyridoxal phosphate binding [GO:0030170] 0.88411 -0.29682 ALGQARDHCRPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.22103 0 0 0 0 0 0 P24386 RAE1_HUMAN Rab proteins geranylgeranyltransferase component A 1 (Choroideremia protein) (Rab escort protein 1) (REP-1) (TCD protein) CHM REP1 TCD Homo sapiens (Human) protein geranylgeranylation [GO:0018344]; protein targeting to membrane [GO:0006612]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]; visual perception [GO:0007601] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; Rab-protein geranylgeranyltransferase complex [GO:0005968] GDP-dissociation inhibitor activity [GO:0005092]; GTPase activator activity [GO:0005096]; Rab geranylgeranyltransferase activity [GO:0004663]; small GTPase binding [GO:0031267] 0.9599 -1.9084 AIIDQFGQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.86802 0 0 9.94994 0 0 0 0 0 P24468 COT2_HUMAN COUP transcription factor 2 (COUP-TF2) (Apolipoprotein A-I regulatory protein 1) (ARP-1) (COUP transcription factor II) (COUP-TF II) (Nuclear receptor subfamily 2 group F member 2) NR2F2 ARP1 TFCOUP2 Homo sapiens (Human) anatomical structure development [GO:0048856]; anterior/posterior pattern specification [GO:0009952]; blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; female gonad development [GO:0008585]; fertilization [GO:0009566]; forebrain development [GO:0030900]; interneuron migration [GO:1904936]; lymphatic endothelial cell fate commitment [GO:0060838]; maternal placenta development [GO:0001893]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of transcription by RNA polymerase II [GO:0000122]; placenta blood vessel development [GO:0060674]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of systemic arterial blood pressure [GO:0003084]; positive regulation of transcription by RNA polymerase II [GO:0045944]; radial pattern formation [GO:0009956]; regulation of transcription by RNA polymerase II [GO:0006357]; response to estradiol [GO:0032355]; skeletal muscle tissue development [GO:0007519]; trophoblast giant cell differentiation [GO:0060707] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA-binding transcription factor activity [GO:0003700]; nuclear receptor activity [GO:0004879]; protein homodimerization activity [GO:0042803]; retinoic acid binding [GO:0001972]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270] 0.73786 0.32498 HYGQFTCEGCK 10.7659 10.8711 10.7897 9.91174 9.27452 10.0293 10.4971 10.4899 10.4839 10.9125 11.0108 10.8162 0 8.97585 9.05061 0 10.6747 10.2759 0 0 0 0 0 0 0 0 0 P24530 EDNRB_HUMAN Endothelin receptor type B (ET-B) (ET-BR) (Endothelin receptor non-selective type) EDNRB ETRB Homo sapiens (Human) aging [GO:0007568]; aldosterone metabolic process [GO:0032341]; calcium ion transmembrane transport [GO:0070588]; calcium-mediated signaling [GO:0019722]; canonical Wnt signaling pathway [GO:0060070]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; cGMP-mediated signaling [GO:0019934]; endothelin receptor signaling pathway [GO:0086100]; enteric nervous system development [GO:0048484]; enteric smooth muscle cell differentiation [GO:0035645]; epithelial fluid transport [GO:0042045]; establishment of endothelial barrier [GO:0061028]; gene expression [GO:0010467]; heparin metabolic process [GO:0030202]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; macrophage chemotaxis [GO:0048246]; melanocyte differentiation [GO:0030318]; negative regulation of adenylate cyclase activity [GO:0007194]; negative regulation of apoptotic process [GO:0043066]; negative regulation of neuron maturation [GO:0014043]; negative regulation of protein metabolic process [GO:0051248]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuroblast migration [GO:0097402]; peripheral nervous system development [GO:0007422]; pharynx development [GO:0060465]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; podocyte differentiation [GO:0072112]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of penile erection [GO:0060406]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of urine volume [GO:0035810]; posterior midgut development [GO:0007497]; protein transmembrane transport [GO:0071806]; regulation of epithelial cell proliferation [GO:0050678]; regulation of fever generation [GO:0031620]; regulation of heart rate [GO:0002027]; regulation of pH [GO:0006885]; regulation of sensory perception of pain [GO:0051930]; renal albumin absorption [GO:0097018]; renal sodium excretion [GO:0035812]; renal sodium ion absorption [GO:0070294]; renin secretion into blood stream [GO:0002001]; response to endothelin [GO:1990839]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; response to sodium phosphate [GO:1904383]; sensory perception of pain [GO:0019233]; vasoconstriction [GO:0042310]; vasodilation [GO:0042311]; vein smooth muscle contraction [GO:0014826] membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886] endothelin receptor activity [GO:0004962]; peptide hormone binding [GO:0017046]; type 1 angiotensin receptor binding [GO:0031702] 0.95607 -1.5929 QSLEEKQSCLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2063 0 0 0 0 0 10.3613 0 0 0 P24534 EF1B_HUMAN Elongation factor 1-beta (EF-1-beta) EEF1B2 EEF1B EF1B Homo sapiens (Human) translational elongation [GO:0006414] cytoplasm [GO:0005737]; cytosol [GO:0005829]; eukaryotic translation elongation factor 1 complex [GO:0005853] guanyl-nucleotide exchange factor activity [GO:0005085]; translation elongation factor activity [GO:0003746] 0.0098522 1.8227 SIQADGLVWGSSK 9.33842 0 9.41517 0 0 0 0 0 9.46148 0 0 9.47452 0 0 0 0 0 0 0 9.62297 0 0 0 0 0 0 0 P24539 AT5F1_HUMAN "ATP synthase F(0) complex subunit B1, mitochondrial (ATP synthase peripheral stalk-membrane subunit b) (ATP synthase proton-transporting mitochondrial F(0) complex subunit B1) (ATP synthase subunit b) (ATPase subunit b)" ATP5PB ATP5F1 Homo sapiens (Human) proton motive force-driven ATP synthesis [GO:0015986]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]; substantia nigra development [GO:0021762] "membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial proton-transporting ATP synthase complex [GO:0005753]; mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) [GO:0000276]; mitochondrion [GO:0005739]; nucleus [GO:0005634]" proton transmembrane transporter activity [GO:0015078] 0.92438 -0.95246 ETIAKCIADLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.08212 0 0 0 9.71265 9.6022 0 0 0 0 0 0 0 P24666 PPAC_HUMAN Low molecular weight phosphotyrosine protein phosphatase (LMW-PTP) (LMW-PTPase) (EC 3.1.3.48) (Adipocyte acid phosphatase) (Low molecular weight cytosolic acid phosphatase) (EC 3.1.3.2) (Red cell acid phosphatase 1) ACP1 Homo sapiens (Human) protein dephosphorylation [GO:0006470] cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; sarcolemma [GO:0042383] acid phosphatase activity [GO:0003993]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; protein tyrosine phosphatase activity [GO:0004725] 0 2.9638 IELLGSYDPQK 0 0 0 0 0 0 9.13999 0 0 0 0 0 0 9.8874 0 0 0 9.51857 0 0 0 9.68993 0 0 0 10.4947 0 P24821 TENA_HUMAN Tenascin (TN) (Cytotactin) (GMEM) (GP 150-225) (Glioma-associated-extracellular matrix antigen) (Hexabrachion) (JI) (Myotendinous antigen) (Neuronectin) (Tenascin-C) (TN-C) TNC HXB Homo sapiens (Human) cell adhesion [GO:0007155]; mesenchymal-epithelial cell signaling involved in prostate gland development [GO:0060739]; morphogenesis of an epithelium [GO:0002009]; neuromuscular junction development [GO:0007528]; osteoblast differentiation [GO:0001649]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; prostate gland epithelium morphogenesis [GO:0060740]; regulation of cell adhesion [GO:0030155]; regulation of cell growth [GO:0001558]; regulation of cell migration [GO:0030334]; regulation of inflammatory response [GO:0050727]; response to wounding [GO:0009611] basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; interstitial matrix [GO:0005614]; membrane [GO:0016020]; perisynaptic extracellular matrix [GO:0098966]; tenascin complex [GO:0090733] extracellular matrix structural constituent [GO:0005201]; syndecan binding [GO:0045545] 0.88496 -0.18938 ITAQGQYELRVDLR 0 0 0 0 0 0 0 0 0 10.3211 10.2766 13.8144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P24863 CCNC_HUMAN Cyclin-C (SRB11 homolog) (hSRB11) CCNC Homo sapiens (Human) G0 to G1 transition [GO:0045023]; negative regulation of Notch signaling pathway [GO:0045746]; positive regulation of transcription by RNA polymerase II [GO:0045944] cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; mediator complex [GO:0016592]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; identical protein binding [GO:0042802] 0.84361 0.15287 IVNDTYR 0 0 0 0 0 0 0 0 0 0 0 10.9003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P24864 CCNE1_HUMAN G1/S-specific cyclin-E1 CCNE1 CCNE Homo sapiens (Human) cell division [GO:0051301]; DNA replication initiation [GO:0006270]; G1/S transition of mitotic cell cycle [GO:0000082]; homologous chromosome pairing at meiosis [GO:0007129]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of mesenchymal stem cell proliferation [GO:1902462]; protein phosphorylation [GO:0006468]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of protein localization [GO:0032880]; telomere maintenance [GO:0000723]; Wnt signaling pathway [GO:0016055] centrosome [GO:0005813]; cyclin E1-CDK2 complex [GO:0097134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; kinase activity [GO:0016301]; protein kinase binding [GO:0019901] 0.95541 -1.5611 DTMKEDGGAEFSAR 0 0 0 0 0 0 0 0 0 0 10.0983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P24903 CP2F1_HUMAN Cytochrome P450 2F1 (EC 1.14.14.1) (CYPIIF1) CYP2F1 Homo sapiens (Human) epoxygenase P450 pathway [GO:0019373]; naphthalene catabolic process [GO:1901170]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805] cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231] "arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; oxygen binding [GO:0019825]" 0.92463 -1.0083 ARLPALKDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.8844 0 0 0 0 0 0 0 P24928 RPB1_HUMAN DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48) POLR2A POLR2 Homo sapiens (Human) DNA-templated transcription termination [GO:0006353]; positive regulation of RNA splicing [GO:0033120]; regulation of DNA-templated transcription [GO:0006355]; transcription by RNA polymerase II [GO:0006366] "chromosome [GO:0005694]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II, core complex [GO:0005665]" DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; kinase binding [GO:0019900]; metal ion binding [GO:0046872]; promoter-specific chromatin binding [GO:1990841]; RNA binding [GO:0003723]; RNA polymerase II activity [GO:0001055]; RNA-dependent RNA polymerase activity [GO:0003968]; ubiquitin protein ligase binding [GO:0031625] 0.89832 -0.59236 DILAKSKGQPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.84414 0 0 0 0 0 11.295 0 11.7266 P25025 CXCR2_HUMAN C-X-C chemokine receptor type 2 (CXC-R2) (CXCR-2) (CDw128b) (GRO/MGSA receptor) (High affinity interleukin-8 receptor B) (IL-8R B) (IL-8 receptor type 2) (CD antigen CD182) CXCR2 IL8RB Homo sapiens (Human) acute inflammatory response to antigenic stimulus [GO:0002438]; cell surface receptor signaling pathway [GO:0007166]; cellular defense response [GO:0006968]; chemotaxis [GO:0006935]; dendritic cell chemotaxis [GO:0002407]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-8-mediated signaling pathway [GO:0038112]; metanephric tubule morphogenesis [GO:0072173]; midbrain development [GO:0030901]; negative regulation of neutrophil apoptotic process [GO:0033030]; neutrophil activation [GO:0042119]; neutrophil chemotaxis [GO:0030593]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of vascular permeability [GO:0043117]; receptor internalization [GO:0031623]; signal transduction [GO:0007165] cell surface [GO:0009986]; mast cell granule [GO:0042629]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; mitotic spindle [GO:0072686]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667] C-X-C chemokine receptor activity [GO:0016494]; G protein-coupled receptor activity [GO:0004930]; interleukin-8 binding [GO:0019959]; interleukin-8 receptor activity [GO:0004918] 0.95504 -1.5559 FRHGLLK 0 0 8.69672 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P25054 APC_HUMAN Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5) APC DP2.5 Homo sapiens (Human) bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell fate specification [GO:0001708]; cell migration [GO:0016477]; DNA damage response [GO:0006974]; endocardial cushion morphogenesis [GO:0003203]; heart valve development [GO:0003170]; mitotic cytokinesis [GO:0000281]; mitotic spindle assembly checkpoint signaling [GO:0007094]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of microtubule depolymerization [GO:0007026]; nervous system development [GO:0007399]; pattern specification process [GO:0007389]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein localization to centrosome [GO:1904781]; positive regulation of pseudopodium assembly [GO:0031274]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein-containing complex assembly [GO:0065003]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell differentiation [GO:0045595]; regulation of microtubule-based process [GO:0032886]; Wnt signaling pathway [GO:0016055] adherens junction [GO:0005912]; beta-catenin destruction complex [GO:0030877]; bicellular tight junction [GO:0005923]; catenin complex [GO:0016342]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; kinetochore [GO:0000776]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; Wnt signalosome [GO:1990909] beta-catenin binding [GO:0008013]; dynein complex binding [GO:0070840]; gamma-catenin binding [GO:0045295]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein kinase binding [GO:0019901]; protein kinase regulator activity [GO:0019887]; ubiquitin protein ligase binding [GO:0031625] 0.89922 -0.63737 ADVNSKK 8.67023 0 0 0 0 0 9.71304 9.24831 0 0 0 10.2068 0 0 0 0 0 0 0 10.5227 0 9.85293 0 0 8.40335 0 0 P25067 CO8A2_HUMAN Collagen alpha-2(VIII) chain (Endothelial collagen) COL8A2 Homo sapiens (Human) angiogenesis [GO:0001525]; camera-type eye morphogenesis [GO:0048593]; cell-cell adhesion [GO:0098609]; epithelial cell proliferation [GO:0050673]; extracellular matrix organization [GO:0030198] basement membrane [GO:0005604]; collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] extracellular matrix structural constituent [GO:0005201]; protein-macromolecule adaptor activity [GO:0030674] 0.81297 0.22165 AGPPGLPGK 9.56123 9.21772 0 0 0 0 0 0 0 0 9.2034 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P25098 ARBK1_HUMAN Beta-adrenergic receptor kinase 1 (Beta-ARK-1) (EC 2.7.11.15) (G-protein coupled receptor kinase 2) GRK2 ADRBK1 BARK BARK1 Homo sapiens (Human) cardiac muscle contraction [GO:0060048]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; negative regulation of relaxation of smooth muscle [GO:1901081]; negative regulation of striated muscle contraction [GO:0045988]; negative regulation of the force of heart contraction by chemical signal [GO:0003108]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of catecholamine secretion [GO:0033605]; protein phosphorylation [GO:0006468]; receptor internalization [GO:0031623]; regulation of the force of heart contraction [GO:0002026]; tachykinin receptor signaling pathway [GO:0007217]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079] cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; presynapse [GO:0098793] alpha-2A adrenergic receptor binding [GO:0031694]; ATP binding [GO:0005524]; beta-adrenergic receptor kinase activity [GO:0047696]; Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled receptor kinase activity [GO:0004703]; protein kinase activity [GO:0004672] 0.91039 -0.74656 LLDSDQELYR 0 0 0 0 0 0 8.68314 0 0 0 0 10.0174 0 0 0 0 0 0 0 0 0 0 0 0 0 8.4048 0 P25100 ADA1D_HUMAN Alpha-1D adrenergic receptor (Alpha-1A adrenergic receptor) (Alpha-1D adrenoreceptor) (Alpha-1D adrenoceptor) (Alpha-adrenergic receptor 1a) ADRA1D ADRA1A Homo sapiens (Human) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell-cell signaling [GO:0007267]; G protein-coupled receptor signaling pathway [GO:0007186]; neuron-glial cell signaling [GO:0150099]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of vasoconstriction [GO:0045907] plasma membrane [GO:0005886] alpha1-adrenergic receptor activity [GO:0004937]; identical protein binding [GO:0042802] 0.95556 -1.5838 LLRCQCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.95042 0 0 0 0 P25205 MCM3_HUMAN DNA replication licensing factor MCM3 (EC 3.6.4.12) (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3) (RLF subunit beta) (p102) MCM3 Homo sapiens (Human) DNA replication initiation [GO:0006270]; DNA strand elongation involved in DNA replication [GO:0006271]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via break-induced replication [GO:0000727]; mitotic DNA replication initiation [GO:1902975]; regulation of DNA-templated DNA replication initiation [GO:0030174] "alpha DNA polymerase:primase complex [GO:0005658]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; CMG complex [GO:0071162]; MCM complex [GO:0042555]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]" ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA binding [GO:0003677]; helicase activity [GO:0004386]; single-stranded DNA binding [GO:0003697] 0 5.9542 AGTVVLDDVELR 0 0 0 0 0 0 8.51483 0 8.20193 10.2511 9.65846 9.72405 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P25311 ZA2G_HUMAN Zinc-alpha-2-glycoprotein (Zn-alpha-2-GP) (Zn-alpha-2-glycoprotein) AZGP1 ZAG ZNGP1 Homo sapiens (Human) cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; immune response [GO:0006955]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895] collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634] protein transmembrane transporter activity [GO:0008320]; RNA nuclease activity [GO:0004540] 0.58172 0.47115 AGEVQEPELR 0 0 0 0 0 0 9.62033 9.97714 9.62355 0 0 0 0 0 0 0 0 0 0 0 9.69568 0 0 0 0 0 0 P25325 THTM_HUMAN 3-mercaptopyruvate sulfurtransferase (MST) (EC 2.8.1.2) MPST TST2 Homo sapiens (Human) cyanate catabolic process [GO:0009440]; hydrogen sulfide biosynthetic process [GO:0070814]; kidney development [GO:0001822]; liver development [GO:0001889]; response to toxic substance [GO:0009636]; spinal cord development [GO:0021510]; sulfur amino acid catabolic process [GO:0000098]; transsulfuration [GO:0019346] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; synapse [GO:0045202] 3-mercaptopyruvate sulfurtransferase activity [GO:0016784]; identical protein binding [GO:0042802]; thiosulfate sulfurtransferase activity [GO:0004792] 0.75684 0.30577 SQPAPAEFR 0 0 0 0 0 0 0 0 8.49077 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P25391 LAMA1_HUMAN Laminin subunit alpha-1 (Laminin A chain) (Laminin-1 subunit alpha) (Laminin-3 subunit alpha) (S-laminin subunit alpha) (S-LAM alpha) LAMA1 LAMA Homo sapiens (Human) branching involved in salivary gland morphogenesis [GO:0060445]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment of epithelial cell apical/basal polarity [GO:0045198]; morphogenesis of an epithelial sheet [GO:0002011]; neuron projection development [GO:0031175]; positive regulation of cell adhesion [GO:0045785]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; protein phosphorylation [GO:0006468]; regulation of basement membrane organization [GO:0110011]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; retinal blood vessel morphogenesis [GO:0061304] basement membrane [GO:0005604]; cell-cell junction [GO:0005911]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; laminin-1 complex [GO:0005606]; laminin-3 complex [GO:0005608]; membrane [GO:0016020]; protein complex involved in cell-matrix adhesion [GO:0098637] extracellular matrix structural constituent [GO:0005201]; glycosphingolipid binding [GO:0043208]; signaling receptor binding [GO:0005102] 0 56.181 AANAPRPGNWILER 13.3105 13.324 13.283 10.6123 10.7378 10.0289 12.9618 12.9628 13.0842 12.7551 12.0847 12.636 10.0253 10.7324 0 9.40092 10.4268 10.4301 9.58035 9.60679 0 0 0 0 0 9.38856 10.4328 P25398 RS12_HUMAN Small ribosomal subunit protein eS12 (40S ribosomal protein S12) RPS12 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; ribosomal small subunit biogenesis [GO:0042274]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0 92.895 AEEGIAAGGVMDVNTALQEVLK 0 0 0 0 0 0 0 8.914 0 0 8.42505 0 0 0 0 0 0 0 0 0 0 0 0 0 9.5769 10.5598 9.15843 P25440 BRD2_HUMAN Bromodomain-containing protein 2 (O27.1.1) (Really interesting new gene 3 protein) BRD2 KIAA9001 RING3 Homo sapiens (Human) neural tube closure [GO:0001843]; nucleosome assembly [GO:0006334]; protein phosphorylation [GO:0006468]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]; protein serine/threonine kinase activity [GO:0004674] 0.63186 0.39959 QPVDAVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.90983 0 0 0 P25685 DNJB1_HUMAN DnaJ homolog subfamily B member 1 (DnaJ protein homolog 1) (Heat shock 40 kDa protein 1) (HSP40) (Heat shock protein 40) (Human DnaJ protein 1) (hDj-1) DNAJB1 DNAJ1 HDJ1 HSPF1 Homo sapiens (Human) cellular response to heat [GO:0034605]; chaperone cofactor-dependent protein refolding [GO:0051085]; forebrain development [GO:0030900]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of ATP-dependent activity [GO:0032781]; regulation of cellular response to heat [GO:1900034]; response to unfolded protein [GO:0006986] cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; sperm head [GO:0061827] ATPase activator activity [GO:0001671]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; Hsp70 protein binding [GO:0030544]; protein folding chaperone [GO:0044183]; protein-folding chaperone binding [GO:0051087]; transcription corepressor activity [GO:0003714]; transcription regulator inhibitor activity [GO:0140416]; unfolded protein binding [GO:0051082] 0 7.9643 DGSDVIYPAR 10.8566 10.8123 11.0922 0 0 0 0 0 9.00846 9.44427 11.0007 10.9098 0 0 0 0 0 0 0 9.5648 0 0 0 0 0 0 0 P25705 ATPA_HUMAN "ATP synthase subunit alpha, mitochondrial (ATP synthase F1 subunit alpha)" ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM Homo sapiens (Human) aging [GO:0007568]; apoptotic process [GO:0006915]; ATP biosynthetic process [GO:0006754]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to nitric oxide [GO:0071732]; lipid metabolic process [GO:0006629]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; proton motive force-driven ATP synthesis [GO:0015986]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]; response to ethanol [GO:0045471]; response to muscle activity [GO:0014850] "cell surface [GO:0009986]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial proton-transporting ATP synthase complex [GO:0005753]; mitochondrial proton-transporting ATP synthase, catalytic core [GO:0005754]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex [GO:0045259]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]" "ADP binding [GO:0043531]; angiostatin binding [GO:0043532]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; MHC class I protein binding [GO:0042288]; protease binding [GO:0002020]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; RNA binding [GO:0003723]" 0 64.7 APGIIPR 10.8537 11.2208 10.9055 10.0035 0 0 11.7676 11.5904 11.6476 0 11.6978 11.6044 11.0483 9.63661 9.46593 0 11.8448 10.0958 12.2609 12.2088 12.2166 12.5985 12.6572 12.1425 14.6607 14.4807 14.3166 P25774 CATS_HUMAN Cathepsin S (EC 3.4.22.27) CTSS Homo sapiens (Human) adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cation channel activity [GO:2001259]; positive regulation of peptidase activity [GO:0010952]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224] collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; phagocytic vesicle [GO:0045335]; tertiary granule lumen [GO:1904724] collagen binding [GO:0005518]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; serine-type endopeptidase activity [GO:0004252] 0.89945 -0.60952 LVSLSAQNLVDCSTEKYGNK 0 0 0 0 9.52968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P25786 PSA1_HUMAN Proteasome subunit alpha type-1 (30 kDa prosomal protein) (PROS-30) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome component C2) (Proteasome nu chain) PSMA1 HC2 NU PROS30 PSC2 Homo sapiens (Human) immune system process [GO:0002376]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] "centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; polysome [GO:0005844]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]" lipopolysaccharide binding [GO:0001530]; RNA binding [GO:0003723] 0.77662 0.26367 ETLPAEQDLTTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.8258 0 0 P25789 PSA4_HUMAN Proteasome subunit alpha type-4 (Macropain subunit C9) (Multicatalytic endopeptidase complex subunit C9) (Proteasome component C9) (Proteasome subunit L) PSMA4 HC9 PSC9 Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] "cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]" 0.28279 0.82714 LLDEVFFSEK 9.21213 9.57577 0 0 0 0 0 0 9.34285 0 9.96379 0 11.9286 0 12.6178 0 0 0 10.3585 10.3416 11.0105 0 10.0312 0 11.2798 9.60162 11.0976 P25800 RBTN1_HUMAN Rhombotin-1 (Cysteine-rich protein TTG-1) (LIM domain only protein 1) (LMO-1) (T-cell translocation protein 1) LMO1 RBTN1 RHOM1 TTG1 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of T cell homeostatic proliferation [GO:0046013] nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA-binding transcription factor binding [GO:0140297]; metal ion binding [GO:0046872]; transcription coactivator activity [GO:0003713] 0.87023 0.040471 EDGVPMLSVQPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.97456 0 0 0 0 0 0 0 0 0 P25940 CO5A3_HUMAN Collagen alpha-3(V) chain COL5A3 Homo sapiens (Human) cell-matrix adhesion [GO:0007160]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; skin development [GO:0043588] collagen type V trimer [GO:0005588]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] collagen binding [GO:0005518]; extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020]; heparin binding [GO:0008201]; proteoglycan binding [GO:0043394] 0.96541 -2.3683 GAKGEPGPDGPPGR 0 0 0 0 0 0 0 0 10.1924 0 0 0 0 0 0 0 0 0 9.25538 0 0 0 0 0 0 0 0 P25942 TNR5_HUMAN Tumor necrosis factor receptor superfamily member 5 (B-cell surface antigen CD40) (Bp50) (CD40L receptor) (CDw40) (CD antigen CD40) CD40 TNFRSF5 Homo sapiens (Human) B cell activation [GO:0042113]; B cell mediated immunity [GO:0019724]; B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; cellular response to interleukin-1 [GO:0071347]; cellular response to mechanical stimulus [GO:0071260]; cellular response to tumor necrosis factor [GO:0071356]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; immune response-regulating cell surface receptor signaling pathway [GO:0002768]; inflammatory response [GO:0006954]; intracellular calcium ion homeostasis [GO:0006874]; platelet activation [GO:0030168]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of GTPase activity [GO:0043547]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein kinase B signaling [GO:0043491]; protein-containing complex assembly [GO:0065003]; response to type II interferon [GO:0034341]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666] CD40 receptor complex [GO:0035631]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886] antigen binding [GO:0003823]; enzyme binding [GO:0019899]; signaling receptor activity [GO:0038023]; ubiquitin protein ligase binding [GO:0031625] 0.84106 0.18192 ETHCHQHK 0 0 0 0 0 0 0 0 9.17707 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P26006 ITA3_HUMAN Integrin alpha-3 (CD49 antigen-like family member C) (FRP-2) (Galactoprotein B3) (GAPB3) (VLA-3 subunit alpha) (CD antigen CD49c) [Cleaved into: Integrin alpha-3 heavy chain; Integrin alpha-3 light chain] ITGA3 MSK18 Homo sapiens (Human) cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; dendritic spine maintenance [GO:0097062]; exploration behavior [GO:0035640]; heart development [GO:0007507]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; lung development [GO:0030324]; maternal process involved in female pregnancy [GO:0060135]; memory [GO:0007613]; mesodermal cell differentiation [GO:0048333]; negative regulation of cell projection organization [GO:0031345]; negative regulation of Rho protein signal transduction [GO:0035024]; nephron development [GO:0072006]; neuron migration [GO:0001764]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of BMP signaling pathway [GO:0030510]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; regulation of Wnt signaling pathway [GO:0030111]; renal filtration [GO:0097205]; response to gonadotropin [GO:0034698]; response to xenobiotic stimulus [GO:0009410]; Rho protein signal transduction [GO:0007266]; skin development [GO:0043588]; synaptic membrane adhesion [GO:0099560] basolateral plasma membrane [GO:0016323]; cell periphery [GO:0071944]; cell surface [GO:0009986]; excitatory synapse [GO:0060076]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone filopodium [GO:1990812]; integrin alpha3-beta1 complex [GO:0034667]; integrin complex [GO:0008305]; neuromuscular junction [GO:0031594]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic active zone membrane [GO:0048787]; receptor complex [GO:0043235]; synaptic membrane [GO:0097060] collagen binding [GO:0005518]; fibronectin binding [GO:0001968]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; metal ion binding [GO:0046872]; protease binding [GO:0002020]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982] 0.93885 -1.2967 CGFFKRAR 0 0 0 0 0 0 0 10.733 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P26010 ITB7_HUMAN Integrin beta-7 (Gut homing receptor beta subunit) ITGB7 Homo sapiens (Human) cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; cell-matrix adhesion involved in ameboidal cell migration [GO:0003366]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; receptor clustering [GO:0043113]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell migration [GO:0072678] cell surface [GO:0009986]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin alpha4-beta7 complex [GO:0034669]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; virus receptor activity [GO:0001618] 0.84234 0.14151 GQQEVLQDQPLSQGAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2682 0 P26012 ITB8_HUMAN Integrin beta-8 ITGB8 Homo sapiens (Human) cartilage development [GO:0051216]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; ganglioside metabolic process [GO:0001573]; hard palate development [GO:0060022]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; Langerhans cell differentiation [GO:0061520]; negative regulation of gene expression [GO:0010629]; placenta blood vessel development [GO:0060674]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; regulation of transforming growth factor beta activation [GO:1901388]; response to virus [GO:0009615]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vasculogenesis [GO:0001570] cell surface [GO:0009986]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin alphav-beta8 complex [GO:0034686]; integrin complex [GO:0008305]; plasma membrane [GO:0005886] extracellular matrix protein binding [GO:1990430]; integrin binding [GO:0005178] 0.96735 -2.8013 KDKLILQSVCTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1591 0 0 0 0 0 0 0 9.71889 0 0 P26038 MOES_HUMAN Moesin (Membrane-organizing extension spike protein) MSN Homo sapiens (Human) cellular response to testosterone stimulus [GO:0071394]; establishment of endothelial barrier [GO:0061028]; establishment of epithelial cell apical/basal polarity [GO:0045198]; gland morphogenesis [GO:0022612]; immunological synapse formation [GO:0001771]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein localization to early endosome [GO:1902966]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of lymphocyte migration [GO:2000401]; regulation of organelle assembly [GO:1902115]; T cell aggregation [GO:0070489]; T cell migration [GO:0072678]; T cell proliferation [GO:0042098] adherens junction [GO:0005912]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; blood microparticle [GO:0072562]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]; uropod [GO:0001931]; vesicle [GO:0031982] actin binding [GO:0003779]; cell adhesion molecule binding [GO:0050839]; double-stranded RNA binding [GO:0003725]; enzyme binding [GO:0019899]; protein kinase binding [GO:0019901]; signaling receptor binding [GO:0005102]; structural constituent of cytoskeleton [GO:0005200] 0 32.916 ALELEQER 12.2582 11.7008 12.493 0 8.43246 0 12.2789 12.3952 12.2682 11.9757 12.1516 12.4089 11.0627 11.5839 13.2074 12.1186 15.0798 14.9689 0 0 0 0 0 0 0 0 0 P26045 PTN3_HUMAN Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1) PTPN3 PTPH1 Homo sapiens (Human) liver regeneration [GO:0097421]; MAPK cascade [GO:0000165]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of mitotic cell cycle [GO:0045930]; protein dephosphorylation [GO:0006470]; regulation of membrane depolarization during action potential [GO:0098902]; regulation of sodium ion transmembrane transporter activity [GO:2000649] cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; plasma membrane [GO:0005886] ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine phosphatase activity [GO:0004725]; sodium channel regulator activity [GO:0017080] 0.95951 -1.7433 ALGGRINNIR 0 0 0 0 0 0 9.60383 0 10.9034 0 0 0 0 0 0 0 0 0 0 0 9.94014 0 0 0 0 0 0 P26196 DDX6_HUMAN Probable ATP-dependent RNA helicase DDX6 (EC 3.6.4.13) (ATP-dependent RNA helicase p54) (DEAD box protein 6) (Oncogene RCK) DDX6 HLR2 RCK Homo sapiens (Human) miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of translation [GO:0017148]; neuron differentiation [GO:0030182]; P-body assembly [GO:0033962]; stem cell population maintenance [GO:0019827]; stress granule assembly [GO:0034063]; viral RNA genome packaging [GO:0019074] cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; P-body [GO:0000932]; RISC complex [GO:0016442] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; cadherin binding [GO:0045296]; helicase activity [GO:0004386]; mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.92181 -1.1253 LPPKDLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.27561 P26232 CTNA2_HUMAN Catenin alpha-2 (Alpha N-catenin) (Alpha-catenin-related protein) CTNNA2 CAPR Homo sapiens (Human) axonogenesis [GO:0007409]; brain morphogenesis [GO:0048854]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; dendrite morphogenesis [GO:0048813]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; prepulse inhibition [GO:0060134]; radial glia guided migration of Purkinje cell [GO:0021942]; regulation of neuron migration [GO:2001222]; regulation of neuron projection development [GO:0010975]; regulation of synapse structural plasticity [GO:0051823] actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; axon [GO:0030424]; catenin complex [GO:0016342]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] actin filament binding [GO:0051015]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; structural constituent of cytoskeleton [GO:0005200] 0 5.2409 IALYCHQLNICSK 10.3711 10.3317 10.2022 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3891 0 0 P26358 DNMT1_HUMAN DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (EC 2.1.1.37) (CXXC-type zinc finger protein 9) (DNA methyltransferase HsaI) (DNA MTase HsaI) (M.HsaI) (MCMT) DNMT1 AIM CXXC9 DNMT Homo sapiens (Human) cellular response to amino acid stimulus [GO:0071230]; cellular response to bisphenol A [GO:1903926]; DNA methylation involved in embryo development [GO:0043045]; DNA methylation on cytosine within a CG sequence [GO:0010424]; DNA methylation-dependent heterochromatin formation [GO:0006346]; DNA-templated transcription [GO:0006351]; negative regulation of gene expression [GO:0010629]; negative regulation of gene expression via CpG island methylation [GO:0044027]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular associated smooth muscle cell apoptotic process [GO:1905460]; negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching [GO:1905931]; positive regulation of gene expression [GO:0010628]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707] female germ cell nucleus [GO:0001674]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; replication fork [GO:0005657] DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA binding [GO:0003677]; DNA-methyltransferase activity [GO:0009008]; methyl-CpG binding [GO:0008327]; promoter-specific chromatin binding [GO:1990841]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270] 0.88353 -0.318 AGVQADEDEDGDEK 10.2601 0 0 0 0 0 0 14.8635 15.0617 0 9.65796 10.5577 8.7269 0 0 0 0 10.1398 0 0 0 9.58808 0 0 0 0 0 P26367 PAX6_HUMAN Paired box protein Pax-6 (Aniridia type II protein) (Oculorhombin) PAX6 AN2 Homo sapiens (Human) anatomical structure development [GO:0048856]; animal organ morphogenesis [GO:0009887]; astrocyte differentiation [GO:0048708]; axon guidance [GO:0007411]; blood vessel development [GO:0001568]; cell fate determination [GO:0001709]; cellular response to leukemia inhibitory factor [GO:1990830]; central nervous system development [GO:0007417]; cerebral cortex regionalization [GO:0021796]; chromatin remodeling [GO:0006338]; commitment of neuronal cell to specific neuron type in forebrain [GO:0021902]; cornea development in camera-type eye [GO:0061303]; DNA demethylation [GO:0080111]; DNA methylation [GO:0006306]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; establishment of mitotic spindle orientation [GO:0000132]; eye development [GO:0001654]; eye photoreceptor cell development [GO:0042462]; forebrain dorsal/ventral pattern formation [GO:0021798]; forebrain-midbrain boundary formation [GO:0021905]; glucose homeostasis [GO:0042593]; habenula development [GO:0021986]; iris morphogenesis [GO:0061072]; keratinocyte differentiation [GO:0030216]; lacrimal gland development [GO:0032808]; lens development in camera-type eye [GO:0002088]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuroblast proliferation [GO:0007405]; neuron fate commitment [GO:0048663]; neuron migration [GO:0001764]; oligodendrocyte cell fate specification [GO:0021778]; pancreatic A cell development [GO:0003322]; pituitary gland development [GO:0021983]; positive regulation of core promoter binding [GO:1904798]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell differentiation [GO:0030858]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to organelle [GO:0033365]; protein phosphorylation [GO:0006468]; regulation of asymmetric cell division [GO:0009786]; regulation of cell migration [GO:0030334]; regulation of timing of cell differentiation [GO:0048505]; regulation of transcription by RNA polymerase II [GO:0006357]; response to wounding [GO:0009611]; retina development in camera-type eye [GO:0060041]; salivary gland morphogenesis [GO:0007435]; signal transduction involved in regulation of gene expression [GO:0023019]; smoothened signaling pathway [GO:0007224]; transcription by RNA polymerase II [GO:0006366]; type B pancreatic cell differentiation [GO:0003309]; ventral spinal cord development [GO:0021517]; visual perception [GO:0007601] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "chromatin DNA binding [GO:0031490]; co-SMAD binding [GO:0070410]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; histone acetyltransferase binding [GO:0035035]; HMG box domain binding [GO:0071837]; protein kinase binding [GO:0019901]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]; transcription coregulator binding [GO:0001221]; ubiquitin protein ligase binding [GO:0031625]" 0.87724 -0.0048658 VATPEVVSK 0 0 0 0 0 0 0 0 0 9.88698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P26368 U2AF2_HUMAN Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit) U2AF2 U2AF65 Homo sapiens (Human) "mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of RNA splicing [GO:0033120]" commitment complex [GO:0000243]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2-type prespliceosome [GO:0071004]; U2AF complex [GO:0089701] C2H2 zinc finger domain binding [GO:0070742]; enzyme binding [GO:0019899]; molecular function inhibitor activity [GO:0140678]; poly-pyrimidine tract binding [GO:0008187]; pre-mRNA 3'-splice site binding [GO:0030628]; RNA binding [GO:0003723] 0.96286 -2.0867 QLNENKQERDK 0 0 0 0 0 0 0 0 0 0 16.0758 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P26373 RL13_HUMAN Large ribosomal subunit protein eL13 (60S ribosomal protein L13) (Breast basic conserved protein 1) RPL13 BBC1 OK/SW-cl.46 Homo sapiens (Human) blastocyst development [GO:0001824]; bone development [GO:0060348]; cytoplasmic translation [GO:0002181]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; endoplasmic reticulum [GO:0005783]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; synapse [GO:0045202] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0 7.2506 GFSLEELR 0 10.8051 0 0 0 0 11.0353 9.50716 10.6266 9.29023 12.4576 9.10899 11.4325 10.5404 11.6378 8.92855 11.8474 11.5577 0 0 0 10.5954 9.81227 10.7255 12.1615 11.025 11.7089 P26374 RAE2_HUMAN Rab proteins geranylgeranyltransferase component A 2 (Choroideremia-like protein) (Rab escort protein 2) (REP-2) CHML REP2 Homo sapiens (Human) intracellular protein transport [GO:0006886]; protein geranylgeranylation [GO:0018344]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Rab-protein geranylgeranyltransferase complex [GO:0005968] GDP-dissociation inhibitor activity [GO:0005092]; GTPase activator activity [GO:0005096]; small GTPase binding [GO:0031267] 0.9629 -2.1798 DTYLVHLTCSSSKTAR 0 0 0 9.32364 0 0 0 0 0 0 0 0 0 0 0 0 11.6742 9.82139 0 0 0 0 0 0 9.84858 0 0 P26439 3BHS2_HUMAN 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 (3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II) (3-beta-HSD II) (3-beta-HSD adrenal and gonadal type) [Includes: 3-beta-hydroxy-Delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid Delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)] HSD3B2 HSDB3B Homo sapiens (Human) androgen biosynthetic process [GO:0006702]; C21-steroid hormone metabolic process [GO:0008207]; hippocampus development [GO:0021766]; response to corticosterone [GO:0051412]; steroid biosynthetic process [GO:0006694] cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; intercellular bridge [GO:0045171]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial membrane [GO:0031966]; nucleolus [GO:0005730]; smooth endoplasmic reticulum membrane [GO:0030868] "3-beta-hydroxy-delta5-steroid dehydrogenase activity [GO:0003854]; cholesterol dehydrogenase activity [GO:0102294]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; steroid delta-isomerase activity [GO:0004769]" 0.96393 -2.1063 ALDKAFRPELREEFSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3804 0 0 0 0 0 0 0 P26440 IVD_HUMAN "Isovaleryl-CoA dehydrogenase, mitochondrial (IVD) (EC 1.3.8.4) (Butyryl-CoA dehydrogenase) (EC 1.3.8.1)" IVD Homo sapiens (Human) branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; leucine catabolic process [GO:0006552] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] butyryl-CoA dehydrogenase activity [GO:0004085]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; isovaleryl-CoA dehydrogenase activity [GO:0008470] 0.95315 -1.4855 QLRQTMAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.8864 0 P26441 CNTF_HUMAN Ciliary neurotrophic factor (CNTF) CNTF Homo sapiens (Human) astrocyte activation [GO:0048143]; ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; muscle organ morphogenesis [GO:0048644]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of photoreceptor cell differentiation [GO:0046533]; neuron development [GO:0048666]; positive regulation of axon regeneration [GO:0048680]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of retinal cell programmed cell death [GO:0046668]; retinal rod cell differentiation [GO:0060221]; signal transduction [GO:0007165]; tyrosine phosphorylation of STAT protein [GO:0007260] axon [GO:0030424]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615] ciliary neurotrophic factor receptor binding [GO:0005127]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-6 receptor binding [GO:0005138]; protein-containing complex binding [GO:0044877] 0.73064 0.33692 SIWLARKIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7859 0 0 0 0 0 0 0 0 0 P26572 MGAT1_HUMAN "Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (EC 2.4.1.101) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I) (GNT-I) (GlcNAc-T I)" MGAT1 GGNT1 GLCT1 GLYT1 MGAT Homo sapiens (Human) in utero embryonic development [GO:0001701]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]; UDP-N-acetylglucosamine catabolic process [GO:0006049]; viral protein processing [GO:0019082] endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular exosome [GO:0070062]; extracellular vesicle [GO:1903561]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471] "acetylglucosaminyltransferase activity [GO:0008375]; alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity [GO:0003827]; manganese ion binding [GO:0030145]" 0.96621 -2.3572 ALGVMDDLK 9.14285 8.99904 0 0 0 0 10.112 9.99464 9.85176 0 9.06091 0 0 0 0 0 0 0 10.6584 0 0 0 9.78329 0 0 0 0 P26583 HMGB2_HUMAN High mobility group protein B2 (High mobility group protein 2) (HMG-2) HMGB2 HMG2 Homo sapiens (Human) cell chemotaxis [GO:0060326]; cellular response to lipopolysaccharide [GO:0071222]; chromatin organization [GO:0006325]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; DNA geometric change [GO:0032392]; DNA topological change [GO:0006265]; double-strand break repair via nonhomologous end joining [GO:0006303]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; inflammatory response to antigenic stimulus [GO:0002437]; innate immune response [GO:0045087]; male gonad development [GO:0008584]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleosome assembly [GO:0006334]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of nuclease activity [GO:0032075]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of neurogenesis [GO:0050767]; regulation of stem cell proliferation [GO:0072091]; regulation of transcription by RNA polymerase II [GO:0006357]; response to lipopolysaccharide [GO:0032496]; response to steroid hormone [GO:0048545]; spermatid nucleus differentiation [GO:0007289]; V(D)J recombination [GO:0033151] chromatin [GO:0000785]; condensed chromosome [GO:0000793]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991] "chemoattractant activity [GO:0042056]; cis-regulatory region sequence-specific DNA binding [GO:0000987]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor binding [GO:0140297]; double-stranded DNA binding [GO:0003690]; four-way junction DNA binding [GO:0000400]; non-sequence-specific DNA binding, bending [GO:0044378]; protein domain specific binding [GO:0019904]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; supercoiled DNA binding [GO:0097100]; transcription cis-regulatory region binding [GO:0000976]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]" 0.96956 -3.3085 ARYDREMK 0 9.37955 0 0 0 10.788 8.6774 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P26599 PTBP1_HUMAN Polypyrimidine tract-binding protein 1 (PTB) (57 kDa RNA-binding protein PPTB-1) (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I) PTBP1 PTB Homo sapiens (Human) "IRES-dependent viral translational initiation [GO:0075522]; mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of muscle cell differentiation [GO:0051148]; negative regulation of RNA splicing [GO:0033119]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of cell differentiation [GO:0045595]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]" extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; mRNA binding [GO:0003729]; poly-pyrimidine tract binding [GO:0008187]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723] 0 54.334 GQPIYIQFSNHK 0 0 0 0 0 0 0 0 0 0 0 0 8.89936 0 9.05403 9.66208 9.92641 0 10.2439 9.07039 9.23731 9.28619 10.6115 10.5633 10.9204 10.8325 10.1769 P26639 SYTC_HUMAN "Threonine--tRNA ligase 1, cytoplasmic (EC 6.1.1.3) (Threonyl-tRNA synthetase) (ThrRS) (Threonyl-tRNA synthetase 1)" TARS1 TARS Homo sapiens (Human) threonyl-tRNA aminoacylation [GO:0006435] cytosol [GO:0005829]; extracellular exosome [GO:0070062] ATP binding [GO:0005524]; identical protein binding [GO:0042802]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270] 0.95962 -1.7458 AELNPWPEYIYTR 0 0 0 0 0 9.96473 0 0 0 0 0 0 0 0 0 9.71576 0 0 10.1127 0 0 0 0 0 0 0 0 P26640 SYVC_HUMAN Valine--tRNA ligase (EC 6.1.1.9) (Protein G7a) (Valyl-tRNA synthetase) (ValRS) VARS1 G7A VARS VARS2 Homo sapiens (Human) tRNA aminoacylation for protein translation [GO:0006418]; valyl-tRNA aminoacylation [GO:0006438] cytosol [GO:0005829] aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; valine-tRNA ligase activity [GO:0004832] 0.96778 -2.9937 EEKGDRIYHQLK 0 0 0 0 0 0 0 0 0 0 18.6844 0 0 0 0 0 0 10.4525 0 11.1642 11.2853 11.6112 0 0 0 0 0 P26641 EF1G_HUMAN Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma) EEF1G EF1G PRO1608 Homo sapiens (Human) response to virus [GO:0009615]; translational elongation [GO:0006414] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634] cadherin binding [GO:0045296]; translation elongation factor activity [GO:0003746] 0 24.792 AAGTLYTYPENWR 12.4783 12.3078 12.3514 0 0 0 11.1609 11.5574 10.6729 10.8485 13.4295 12.9446 0 9.9714 9.97456 12.0496 9.81959 11.0955 0 9.95902 9.96723 9.65775 10.8829 10.9873 13.0024 11.5488 12.927 P26678 PPLA_HUMAN Cardiac phospholamban (PLB) PLN PLB Homo sapiens (Human) acrosome assembly [GO:0001675]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process [GO:0086023]; blood circulation [GO:0008015]; cardiac muscle tissue development [GO:0048738]; intracellular calcium ion homeostasis [GO:0006874]; muscle cell cellular homeostasis [GO:0046716]; negative regulation of ATP-dependent activity [GO:0032780]; negative regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901895]; negative regulation of calcium ion binding [GO:1901877]; negative regulation of calcium ion import [GO:0090281]; negative regulation of calcium ion import into sarcoplasmic reticulum [GO:1902081]; negative regulation of calcium ion transmembrane transporter activity [GO:1901020]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of catalytic activity [GO:0043086]; negative regulation of heart rate [GO:0010459]; Notch signaling pathway [GO:0007219]; regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901894]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle cell membrane potential [GO:0086036]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of heart contraction [GO:0008016]; regulation of relaxation of cardiac muscle [GO:1901897]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of the force of heart contraction [GO:0002026]; regulation of the force of heart contraction by cardiac conduction [GO:0086092]; relaxation of cardiac muscle [GO:0055119] calcium ion-transporting ATPase complex [GO:0090534]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; perinuclear region of cytoplasm [GO:0048471]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017] ATPase binding [GO:0051117]; ATPase inhibitor activity [GO:0042030]; enzyme inhibitor activity [GO:0004857]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803] 0.94915 -1.3711 RASTIEMPQQARQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5551 0 0 0 0 0 0 0 0 0 0 0 0 P26715 NKG2A_HUMAN NKG2-A/NKG2-B type II integral membrane protein (CD159 antigen-like family member A) (NK cell receptor A) (NKG2-A/B-activating NK receptor) (CD antigen CD159a) KLRC1 NKG2A Homo sapiens (Human) "adaptive immune response [GO:0002250]; CD8-positive, gamma-delta intraepithelial T cell differentiation [GO:0002305]; cell surface receptor signaling pathway [GO:0007166]; innate immune response [GO:0045087]; natural killer cell inhibitory signaling pathway [GO:0002769]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of T cell mediated cytotoxicity [GO:0001915]; regulation of natural killer cell activation [GO:0032814]" plasma membrane [GO:0005886]; receptor complex [GO:0043235] carbohydrate binding [GO:0030246]; HLA-E specific inhibitory MHC class Ib receptor activity [GO:0062082]; MHC class I protein complex binding [GO:0023024]; transmembrane signaling receptor activity [GO:0004888] 0.87685 -0.011431 HNNSSLNTRTQKAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0042 0 P26717 NKG2C_HUMAN NKG2-C type II integral membrane protein (CD159 antigen-like family member C) (NK cell receptor C) (NKG2-C-activating NK receptor) (CD antigen CD159c) KLRC2 NKG2C Homo sapiens (Human) adaptive immune response [GO:0002250]; cellular defense response [GO:0006968]; natural killer cell mediated immunity [GO:0002228]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; regulation of natural killer cell activation [GO:0032814]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223] plasma membrane [GO:0005886]; receptor complex [GO:0043235] activating MHC class Ib receptor activity [GO:0062081]; carbohydrate binding [GO:0030246]; MHC class I protein complex binding [GO:0023024]; protein antigen binding [GO:1990405]; transmembrane signaling receptor activity [GO:0004888] 0.87078 0.039341 FLASILPSSWIGVFR 0 0 0 0 0 0 0 0 0 0 0 0 10.7875 0 0 0 11.5734 0 0 0 0 0 0 0 0 0 0 P26885 FKBP2_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP2 (PPIase FKBP2) (EC 5.2.1.8) (13 kDa FK506-binding protein) (13 kDa FKBP) (FKBP-13) (FK506-binding protein 2) (FKBP-2) (Immunophilin FKBP13) (Rotamase) FKBP2 FKBP13 Homo sapiens (Human) chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789] FK506 binding [GO:0005528]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755] 0.87985 0.017394 GDVLHMHYTGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.73137 P26951 IL3RA_HUMAN Interleukin-3 receptor subunit alpha (IL-3 receptor subunit alpha) (IL-3R subunit alpha) (IL-3R-alpha) (IL-3RA) (CD antigen CD123) IL3RA IL3R Homo sapiens (Human) cytokine-mediated signaling pathway [GO:0019221]; interleukin-3-mediated signaling pathway [GO:0038156] external side of plasma membrane [GO:0009897]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interleukin-3 receptor activity [GO:0004912] 0.88355 -0.11989 AQQLTWDLNR 0 0 0 0 0 0 0 0 10.2494 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P27037 AVR2A_HUMAN Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) (ACTRIIA) ACVR2A ACVR2 Homo sapiens (Human) activin receptor signaling pathway [GO:0032924]; anterior/posterior pattern specification [GO:0009952]; BMP signaling pathway [GO:0030509]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; determination of left/right symmetry [GO:0007368]; embryonic skeletal system development [GO:0048706]; gastrulation with mouth forming second [GO:0001702]; mesoderm development [GO:0007498]; odontogenesis of dentin-containing tooth [GO:0042475]; penile erection [GO:0043084]; positive regulation of activin receptor signaling pathway [GO:0032927]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of nitric-oxide synthase activity [GO:0050999]; Sertoli cell proliferation [GO:0060011]; sperm ejaculation [GO:0042713]; spermatogenesis [GO:0007283]; transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178] activin receptor complex [GO:0048179]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; inhibin-betaglycan-ActRII complex [GO:0034673]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] activin binding [GO:0048185]; ATP binding [GO:0005524]; BMP receptor activity [GO:0098821]; coreceptor activity [GO:0015026]; growth factor binding [GO:0019838]; inhibin binding [GO:0034711]; kinase activator activity [GO:0019209]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; transmembrane receptor protein serine/threonine kinase activity [GO:0004675] 0.7642 0.28669 GAAAKLAFAVFLISCSSGAILGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.30706 0 0 0 0 0 0 P27144 KAD4_HUMAN "Adenylate kinase 4, mitochondrial (AK 4) (EC 2.7.4.10) (EC 2.7.4.6) (Adenylate kinase 3-like) (GTP:AMP phosphotransferase AK4)" AK4 AK3 AK3L1 Homo sapiens (Human) ADP biosynthetic process [GO:0006172]; AMP metabolic process [GO:0046033]; ATP metabolic process [GO:0046034]; cellular response to hypoxia [GO:0071456]; GTP metabolic process [GO:0046039]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside triphosphate biosynthetic process [GO:0009142]; phosphorylation [GO:0016310]; regulation of oxidative phosphorylation [GO:0002082]; ribonucleoside diphosphate biosynthetic process [GO:0009188] cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; GTP binding [GO:0005525]; nucleoside diphosphate kinase activity [GO:0004550]; nucleoside monophosphate kinase activity [GO:0050145]; nucleoside triphosphate adenylate kinase activity [GO:0046899] 0.96942 -3.1544 ENIKASTEVGEMAK 0 0 0 0 0 0 0 0 0 9.69256 0 0 0 0 0 0 0 0 0 0 10.0215 0 9.65272 0 0 0 0 P27216 ANX13_HUMAN Annexin A13 (Annexin XIII) (Annexin-13) (Intestine-specific annexin) (ISA) ANXA13 ANX13 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; positive regulation of Golgi to plasma membrane protein transport [GO:0042998] apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; exocytic vesicle [GO:0070382]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extrinsic component of membrane [GO:0019898]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; phosphatidylglycerol binding [GO:1901611]; phosphatidylserine binding [GO:0001786] 0.95278 -1.4679 AEVDLQGIK 0 9.54934 9.36761 8.45282 0 0 15.4768 9.40867 15.4113 15.018 0 14.9728 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P27338 AOFB_HUMAN Amine oxidase [flavin-containing] B (EC 1.4.3.21) (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B) MAOB Homo sapiens (Human) dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; response to toxic substance [GO:0009636]; response to xenobiotic stimulus [GO:0009410]; substantia nigra development [GO:0021762] mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739] aliphatic amine oxidase activity [GO:0052595]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; monoamine oxidase activity [GO:0097621]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131] 0.1184 1.1072 IISTTNGGQER 0 0 0 0 10.4505 0 0 0 0 11.4225 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P27348 1433T_HUMAN 14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1) YWHAQ Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of monoatomic ion transmembrane transport [GO:0034766]; protein targeting [GO:0006605]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; substantia nigra development [GO:0021762] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; protein-containing complex [GO:0032991]; synapse [GO:0045202] 14-3-3 protein binding [GO:0071889]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; transmembrane transporter binding [GO:0044325] 0 3.9601 AVTEQGAELSNEER 0 0 0 0 0 0 0 9.05599 8.89154 10.257 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.41627 P27352 IF_HUMAN Cobalamin binding intrinsic factor (Gastric intrinsic factor) (Intrinsic factor) (IF) (INF) CBLIF GIF IFMH Homo sapiens (Human) cobalamin transport [GO:0015889]; cobalt ion transport [GO:0006824] apical plasma membrane [GO:0016324]; endosome [GO:0005768]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]; microvillus [GO:0005902] cargo receptor ligand activity [GO:0140355]; cobalamin binding [GO:0031419] 0.81761 0.21991 TTDMILNEIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4449 0 0 P27361 MK03_HUMAN Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC 2.7.11.24) (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (Microtubule-associated protein 2 kinase) (p44-ERK1) MAPK3 ERK1 PRKM3 Homo sapiens (Human) apoptotic process [GO:0006915]; Bergmann glial cell differentiation [GO:0060020]; BMP signaling pathway [GO:0030509]; cardiac neural crest cell development involved in heart development [GO:0061308]; cartilage development [GO:0051216]; caveolin-mediated endocytosis [GO:0072584]; cell cycle [GO:0007049]; cellular response to amino acid starvation [GO:0034198]; cellular response to cadmium ion [GO:0071276]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cellular response to tumor necrosis factor [GO:0071356]; DNA-templated transcription [GO:0006351]; ERK1 and ERK2 cascade [GO:0070371]; face development [GO:0060324]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; interleukin-1-mediated signaling pathway [GO:0070498]; intracellular signal transduction [GO:0035556]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lung morphogenesis [GO:0060425]; MAPK cascade [GO:0000165]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of apolipoprotein binding [GO:2000657]; outer ear morphogenesis [GO:0042473]; peptidyl-tyrosine autophosphorylation [GO:0038083]; phosphorylation [GO:0016310]; positive regulation of cyclase activity [GO:0031281]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of macrophage proliferation [GO:0120041]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of xenophagy [GO:1904417]; protein phosphorylation [GO:0006468]; regulation of cellular pH [GO:0030641]; regulation of cytoskeleton organization [GO:0051493]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of Golgi inheritance [GO:0090170]; regulation of ossification [GO:0030278]; regulation of stress-activated MAPK cascade [GO:0032872]; response to epidermal growth factor [GO:0070849]; response to exogenous dsRNA [GO:0043330]; sensory perception of pain [GO:0019233]; signal transduction in response to DNA damage [GO:0042770]; stress-activated MAPK cascade [GO:0051403]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; trachea formation [GO:0060440]; xenophagy [GO:0098792] caveola [GO:0005901]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143] ATP binding [GO:0005524]; DNA-binding transcription factor binding [GO:0140297]; identical protein binding [GO:0042802]; MAP kinase activity [GO:0004707]; MAP kinase kinase activity [GO:0004708]; phosphatase binding [GO:0019902]; phosphotyrosine residue binding [GO:0001784]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.82967 0.20743 DILRASTLEAMR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2599 0 0 0 0 0 0 0 0 0 0 0 0 0 P27482 CALL3_HUMAN Calmodulin-like protein 3 (CaM-like protein) (CLP) (Calmodulin-related protein NB-1) CALML3 Homo sapiens (Human) extracellular exosome [GO:0070062] calcium ion binding [GO:0005509] 0.86384 0.077596 ADQLTEEQVTEFKEAFSLFDK 8.9191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P27487 DPP4_HUMAN Dipeptidyl peptidase 4 (EC 3.4.14.5) (ADABP) (Adenosine deaminase complexing protein 2) (ADCP-2) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (CD antigen CD26) [Cleaved into: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)] DPP4 ADCP2 CD26 Homo sapiens (Human) behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; glucagon processing [GO:0120116]; locomotory exploration behavior [GO:0035641]; membrane fusion [GO:0061025]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of neutrophil chemotaxis [GO:0090024]; peptide hormone processing [GO:0016486]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; viral entry into host cell [GO:0046718] apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; intercellular canaliculus [GO:0046581]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886] aminopeptidase activity [GO:0004177]; chemorepellent activity [GO:0045499]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618] 0.85019 0.11676 MLQNVQMPSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.03886 0 0 0 0 0 0 0 0 0 0 0 P27539 GDF1_HUMAN Embryonic growth/differentiation factor 1 (GDF-1) GDF1 Homo sapiens (Human) BMP signaling pathway [GO:0030509]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; SMAD protein signal transduction [GO:0060395] extracellular space [GO:0005615] cytokine activity [GO:0005125]; growth factor activity [GO:0008083] 0.86059 0.093256 LYVSFREVGWHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.86022 0 0 0 0 0 0 P27540 ARNT_HUMAN "Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Class E basic helix-loop-helix protein 2) (bHLHe2) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1-beta) (HIF-1-beta) (HIF1-beta)" ARNT BHLHE2 Homo sapiens (Human) cell differentiation [GO:0030154]; embryonic placenta development [GO:0001892]; negative regulation of inflammatory response [GO:0050728]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of glycolytic process [GO:0045821]; positive regulation of hormone biosynthetic process [GO:0046886]; positive regulation of protein sumoylation [GO:0033235]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nuclear aryl hydrocarbon receptor complex [GO:0034753]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575] "aryl hydrocarbon receptor binding [GO:0017162]; cis-regulatory region sequence-specific DNA binding [GO:0000987]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; nuclear receptor activity [GO:0004879]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.40525 0.70259 NKMTAYITELSDMVPTCSALAR 0 0 0 12.3677 12.6914 0 0 0 0 0 0 0 12.3975 0 0 0 0 12.4785 0 0 0 0 0 0 0 0 0 P27658 CO8A1_HUMAN Collagen alpha-1(VIII) chain (Endothelial collagen) [Cleaved into: Vastatin] COL8A1 C3orf7 Homo sapiens (Human) angiogenesis [GO:0001525]; camera-type eye morphogenesis [GO:0048593]; cell adhesion [GO:0007155]; endodermal cell differentiation [GO:0035987]; epithelial cell proliferation [GO:0050673]; extracellular matrix organization [GO:0030198]; positive regulation of cell-substrate adhesion [GO:0010811] collagen type VIII trimer [GO:0005591]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] extracellular matrix structural constituent [GO:0005201] 0.82966 0.20786 GEGGIVGPQGPPGPK 0 11.0123 0 0 0 0 0 0 10.6962 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P27694 RFA1_HUMAN "Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]" RPA1 REPA1 RPA70 Homo sapiens (Human) base-excision repair [GO:0006284]; DNA damage response [GO:0006974]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA-templated DNA replication [GO:0006261]; double-strand break repair via homologous recombination [GO:0000724]; meiotic cell cycle [GO:0051321]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; protein localization to chromosome [GO:0034502]; telomere maintenance [GO:0000723]; telomere maintenance via telomerase [GO:0007004] "chromosome, telomeric region [GO:0000781]; DNA replication factor A complex [GO:0005662]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; site of DNA damage [GO:0090734]" damaged DNA binding [GO:0003684]; G-rich strand telomeric DNA binding [GO:0098505]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]; single-stranded telomeric DNA binding [GO:0043047] 0.94584 -1.3436 CEKCDTEFPNFK 0 0 0 0 0 0 0 9.47806 0 0 0 0 0 9.72238 0 0 0 0 0 0 0 0 0 0 0 0 0 P27695 APEX1_HUMAN "DNA-(apurinic or apyrimidinic site) endonuclease (EC 3.1.11.2) (APEX nuclease) (APEN) (Apurinic-apyrimidinic endonuclease 1) (AP endonuclease 1) (APE-1) (REF-1) (Redox factor-1) [Cleaved into: DNA-(apurinic or apyrimidinic site) endonuclease, mitochondrial]" APEX1 APE APE1 APEX APX HAP1 REF1 Homo sapiens (Human) "aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA catabolic process [GO:0006308]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; response to xenobiotic stimulus [GO:0009410]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]" "centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription regulator complex [GO:0005667]" "3'-5' exonuclease activity [GO:0008408]; 3'-5'-DNA exonuclease activity [GO:0008296]; chromatin DNA binding [GO:0031490]; class II DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0052720]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA endonuclease activity [GO:0004520]; DNA-(abasic site) binding [GO:0140431]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; double-stranded DNA 3'-5' DNA exonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:0090580]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]" 0.87709 -0.011102 ALGSDHCPITLYLAL 0 0 0 0 0 0 0 0 0 0 0 0 9.69565 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P27701 CD82_HUMAN CD82 antigen (C33 antigen) (IA4) (Inducible membrane protein R2) (Metastasis suppressor Kangai-1) (Suppressor of tumorigenicity 6 protein) (Tetraspanin-27) (Tspan-27) (CD antigen CD82) CD82 KAI1 SAR2 ST6 TSPAN27 Homo sapiens (Human) extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] 0.96175 -2.5603 MGSACIK 0 0 0 8.30214 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P27707 DCK_HUMAN Deoxycytidine kinase (dCK) (EC 2.7.1.74) (Deoxyadenosine kinase) (EC 2.7.1.76) (Deoxyguanosine kinase) (EC 2.7.1.113) DCK Homo sapiens (Human) dAMP salvage [GO:0106383]; nucleoside phosphate biosynthetic process [GO:1901293]; phosphorylation [GO:0016310]; pyrimidine nucleotide metabolic process [GO:0006220] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] ATP binding [GO:0005524]; cytidine kinase activity [GO:0043771]; deoxyadenosine kinase activity [GO:0004136]; deoxycytidine kinase activity [GO:0004137]; deoxyguanosine kinase activity [GO:0004138]; protein homodimerization activity [GO:0042803] 0.78815 0.24738 ISIEGNIAAGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0786 0 0 0 0 0 0 0 0 0 0 0 0 P27708 PYR1_HUMAN CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)] CAD Homo sapiens (Human) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; citrulline biosynthetic process [GO:0019240]; glutamine metabolic process [GO:0006541]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777]; UDP biosynthetic process [GO:0006225]; UTP biosynthetic process [GO:0006228] cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]; terminal bouton [GO:0043195] aspartate binding [GO:0070335]; aspartate carbamoyltransferase activity [GO:0004070]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; dihydroorotase activity [GO:0004151]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]; zinc ion binding [GO:0008270] 0 8.3462 AALVLEDGSVLR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.93783 0 9.19163 0 10.5578 0 0 8.36462 0 9.57355 10.6719 9.65136 9.46007 10.24 P27797 CALR_HUMAN Calreticulin (CRP55) (Calregulin) (Endoplasmic reticulum resident protein 60) (ERp60) (HACBP) (grp60) CALR CRTC Homo sapiens (Human) cardiac muscle cell differentiation [GO:0055007]; cellular response to electrical stimulus [GO:0071257]; cellular response to lithium ion [GO:0071285]; cellular response to virus [GO:0098586]; cellular senescence [GO:0090398]; cortical actin cytoskeleton organization [GO:0030866]; glucocorticoid receptor signaling pathway [GO:0042921]; intracellular calcium ion homeostasis [GO:0006874]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of retinoic acid receptor signaling pathway [GO:0048387]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of translation [GO:0017148]; negative regulation of trophoblast cell migration [GO:1901164]; peptide antigen assembly with MHC class I protein complex [GO:0002502]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of gene expression [GO:0010628]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of phagocytosis [GO:0050766]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein export from nucleus [GO:0006611]; protein folding [GO:0006457]; protein folding in endoplasmic reticulum [GO:0034975]; protein localization to nucleus [GO:0034504]; protein maturation by protein folding [GO:0022417]; protein stabilization [GO:0050821]; regulation of apoptotic process [GO:0042981]; regulation of DNA-templated transcription [GO:0006355]; regulation of meiotic nuclear division [GO:0040020]; response to estradiol [GO:0032355]; response to glycoside [GO:1903416]; response to testosterone [GO:0033574]; response to xenobiotic stimulus [GO:0009410]; selective autophagy [GO:0061912]; sequestering of calcium ion [GO:0051208]; spermatogenesis [GO:0007283]; ubiquitin-dependent ERAD pathway [GO:0030433] acrosomal vesicle [GO:0001669]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cortical granule [GO:0060473]; cytolytic granule [GO:0044194]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle lumen [GO:0071682]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum quality control compartment [GO:0044322]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; lumenal side of endoplasmic reticulum membrane [GO:0098553]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; polysome [GO:0005844]; sarcoplasmic reticulum lumen [GO:0033018]; smooth endoplasmic reticulum [GO:0005790] calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q complex binding [GO:0001849]; DNA binding [GO:0003677]; hormone binding [GO:0042562]; integrin binding [GO:0005178]; iron ion binding [GO:0005506]; mRNA binding [GO:0003729]; nuclear androgen receptor binding [GO:0050681]; nuclear export signal receptor activity [GO:0005049]; peptide binding [GO:0042277]; protein folding chaperone [GO:0044183]; protein-folding chaperone binding [GO:0051087]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; zinc ion binding [GO:0008270] 0 30.007 EQFLDGDGWTSR 0 0 9.10489 0 0 0 10.3989 10.5247 10.4802 0 0 0 0 9.18192 0 0 0 0 11.9313 11.8817 11.7971 11.5284 11.0067 11.5671 12.2869 12.1478 11.8402 P27815 PDE4A_HUMAN "cAMP-specific 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.53) (DPDE2) (PDE46)" PDE4A DPDE2 Homo sapiens (Human) cAMP catabolic process [GO:0006198]; cellular response to xenobiotic stimulus [GO:0071466]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0106070]; regulation of protein kinase A signaling [GO:0010738]; sensory perception of smell [GO:0007608]; signal transduction [GO:0007165] cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587] "3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; metal ion binding [GO:0046872]" 0.90685 -0.71232 ESFLYRSDSDYDMSPK 9.4616 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P27816 MAP4_HUMAN Microtubule-associated protein 4 (MAP-4) MAP4 Homo sapiens (Human) cell division [GO:0051301]; cilium disassembly [GO:0061523]; establishment of spindle orientation [GO:0051294]; microtubule cytoskeleton organization [GO:0000226]; microtubule polymerization [GO:0046785]; microtubule sliding [GO:0051012]; mitotic spindle organization [GO:0007052]; negative regulation of non-motile cilium assembly [GO:1902856]; neuron projection development [GO:0031175] axon [GO:0030424]; axoneme [GO:0005930]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; microtubule organizing center [GO:0005815]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005] microtubule binding [GO:0008017]; microtubule stabilizing activity [GO:0140778]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198] 0.96173 -2.5895 ASPIKMDLAPSKDMGPPK 9.35387 9.49297 0 0 0 0 8.59119 9.03551 9.13394 9.18666 9.54722 10.2709 0 0 9.6977 0 0 8.63902 0 0 0 0 0 0 0 0 0 P27824 CALX_HUMAN Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90) CANX Homo sapiens (Human) aging [GO:0007568]; clathrin-dependent endocytosis [GO:0072583]; protein folding [GO:0006457]; protein folding in endoplasmic reticulum [GO:0034975]; protein secretion [GO:0009306]; synaptic vesicle endocytosis [GO:0048488]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral protein processing [GO:0019082] axon [GO:0030424]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum quality control compartment [GO:0044322]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; lumenal side of endoplasmic reticulum membrane [GO:0098553]; melanosome [GO:0042470]; membrane [GO:0016020]; mitochondria-associated endoplasmic reticulum membrane [GO:0044233]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; postsynaptic membrane [GO:0045211]; presynaptic active zone membrane [GO:0048787]; protein-containing complex [GO:0032991]; ribosome [GO:0005840]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790] apolipoprotein binding [GO:0034185]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; ionotropic glutamate receptor binding [GO:0035255]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082] 0 11.198 AEEDEILNR 9.12 0 10.2321 0 0 0 10.7955 9.4275 10.487 0 0 0 0 0 0 0 0 0 9.58845 10.3116 11.4391 8.64227 9.05837 8.74655 12.1509 11.5031 11.326 P27986 P85A_HUMAN Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha) PIK3R1 GRB1 Homo sapiens (Human) B cell differentiation [GO:0030183]; cellular response to insulin stimulus [GO:0032869]; cellular response to UV [GO:0034644]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; growth hormone receptor signaling pathway [GO:0060396]; immune response [GO:0006955]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; intracellular glucose homeostasis [GO:0001678]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; myeloid leukocyte migration [GO:0097529]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of stress fiber assembly [GO:0051497]; osteoclast differentiation [GO:0030316]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion disassembly [GO:0120183]; positive regulation of glucose import [GO:0046326]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; response to endoplasmic reticulum stress [GO:0034976]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell differentiation [GO:0030217]; transcription by RNA polymerase II [GO:0006366] "cell-cell junction [GO:0005911]; cis-Golgi network [GO:0005801]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum membrane [GO:1990578]; perinuclear region of cytoplasm [GO:0048471]; phosphatidylinositol 3-kinase complex [GO:0005942]; phosphatidylinositol 3-kinase complex, class IA [GO:0005943]; plasma membrane [GO:0005886]" 1-phosphatidylinositol-3-kinase regulator activity [GO:0046935]; ErbB-3 class receptor binding [GO:0043125]; insulin binding [GO:0043559]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; insulin-like growth factor receptor binding [GO:0005159]; kinase activator activity [GO:0019209]; neurotrophin TRKA receptor binding [GO:0005168]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphatidylinositol 3-kinase regulator activity [GO:0035014]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068] 0.3839 0.7181 KLHEYNTQFQEK 0 0 0 0 0 0 0 0 0 0 0 12.1772 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P28039 AOAH_HUMAN Acyloxyacyl hydrolase (EC 3.1.1.77) [Cleaved into: Acyloxyacyl hydrolase small subunit; Acyloxyacyl hydrolase large subunit] AOAH Homo sapiens (Human) fatty acid metabolic process [GO:0006631]; lipopolysaccharide catabolic process [GO:0009104]; negative regulation of inflammatory response [GO:0050728] cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576] acyloxyacyl hydrolase activity [GO:0050528]; calcium ion binding [GO:0005509] 0.88399 -0.32568 AEQLSNTLKK 0 0 0 0 0 0 0 0 0 0 10.2913 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P28066 PSA5_HUMAN Proteasome subunit alpha type-5 (Macropain zeta chain) (Multicatalytic endopeptidase complex zeta chain) (Proteasome zeta chain) PSMA5 Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] "cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; secretory granule lumen [GO:0034774]" 0.084453 1.23 AIGSASEGAQSSLQEVYHK 8.8421 0 0 0 0 0 0 0 0 0 0 0 0 8.65019 0 0 10.0236 0 0 0 0 0 0 0 9.58357 0 0 P28070 PSB4_HUMAN Proteasome subunit beta type-4 (26 kDa prosomal protein) (HsBPROS26) (PROS-26) (Macropain beta chain) (Multicatalytic endopeptidase complex beta chain) (Proteasome beta chain) (Proteasome chain 3) (HsN3) PSMB4 PROS26 Homo sapiens (Human) negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] "ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]" lipopolysaccharide binding [GO:0001530] 0.90622 -0.71255 AIHSWLTR 0 8.74005 0 0 0 0 0 0 0 0 9.5987 9.4652 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P28072 PSB6_HUMAN Proteasome subunit beta type-6 (EC 3.4.25.1) (Macropain delta chain) (Multicatalytic endopeptidase complex delta chain) (Proteasome delta chain) (Proteasome subunit Y) PSMB6 LMPY Y Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] "cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]" cadherin binding [GO:0045296]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298] 0 4.1192 LAAIAESGVER 0 0 0 0 0 0 0 0 0 9.30255 9.18063 9.04821 0 0 0 0 0 0 0 0 0 0 0 9.313 0 0 0 P28074 PSB5_HUMAN Proteasome subunit beta type-5 (EC 3.4.25.1) (Macropain epsilon chain) (Multicatalytic endopeptidase complex epsilon chain) (Proteasome chain 6) (Proteasome epsilon chain) (Proteasome subunit MB1) (Proteasome subunit X) PSMB5 LMPX MB1 X Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; proteolysis [GO:0006508]; response to oxidative stress [GO:0006979] "centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]" endopeptidase activity [GO:0004175]; peptidase activity [GO:0008233]; threonine-type endopeptidase activity [GO:0004298] 0.41932 0.67743 AIYQATYR 0 0 0 0 0 0 0 0 0 0 0 10.0378 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P28222 5HT1B_HUMAN 5-hydroxytryptamine receptor 1B (5-HT-1B) (5-HT1B) (S12) (Serotonin 1D beta receptor) (5-HT-1D-beta) (Serotonin receptor 1B) HTR1B HTR1DB Homo sapiens (Human) "adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adenylate cyclase-inhibiting serotonin receptor signaling pathway [GO:0007198]; bone remodeling [GO:0046849]; cellular response to alkaloid [GO:0071312]; cellular response to temperature stimulus [GO:0071502]; cellular response to xenobiotic stimulus [GO:0071466]; chemical synaptic transmission [GO:0007268]; drinking behavior [GO:0042756]; G protein-coupled receptor internalization [GO:0002031]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; negative regulation of serotonin secretion [GO:0014063]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of behavior [GO:0050795]; regulation of dopamine secretion [GO:0014059]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to cocaine [GO:0042220]; response to ethanol [GO:0045471]; response to mineralocorticoid [GO:0051385]; vasoconstriction [GO:0042310]" calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; G protein-coupled serotonin receptor complex [GO:0098666]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; serotonergic synapse [GO:0099154] G protein-coupled serotonin receptor activity [GO:0004993]; neurotransmitter receptor activity [GO:0030594]; serotonin binding [GO:0051378]; voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels [GO:0099626] 0.95314 -1.4854 IYVEARSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1687 0 0 0 0 0 P28288 ABCD3_HUMAN ATP-binding cassette sub-family D member 3 (EC 3.1.2.-) (EC 7.6.2.-) (70 kDa peroxisomal membrane protein) (PMP70) ABCD3 PMP70 PXMP1 Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; bile acid biosynthetic process [GO:0006699]; fatty acid beta-oxidation [GO:0006635]; fatty acid biosynthetic process [GO:0006633]; long-chain fatty acid import into peroxisome [GO:0015910]; peroxisome organization [GO:0007031]; phytanic acid metabolic process [GO:1903512]; response to organic cyclic compound [GO:0014070]; response to xenobiotic stimulus [GO:0009410]; very long-chain fatty acid catabolic process [GO:0042760]; very long-chain fatty acid metabolic process [GO:0000038] cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777] ABC-type transporter activity [GO:0140359]; acyl-CoA hydrolase activity [GO:0047617]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]; long-chain fatty acid transporter activity [GO:0005324]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621] 0.88369 -0.25742 DQVIYPDGR 0 0 0 0 0 0 0 0 0 0 0 10.5113 0 0 0 0 0 0 0 0 0 0 9.62337 0 0 9.66708 0 P28289 TMOD1_HUMAN Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod) TMOD1 D9S57E TMOD Homo sapiens (Human) adult locomotory behavior [GO:0008344]; lens fiber cell development [GO:0070307]; muscle contraction [GO:0006936]; myofibril assembly [GO:0030239]; pointed-end actin filament capping [GO:0051694] actin filament [GO:0005884]; cortical cytoskeleton [GO:0030863]; cytosol [GO:0005829]; membrane [GO:0016020]; myofibril [GO:0030016]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865] actin binding [GO:0003779]; tropomyosin binding [GO:0005523] 0.90753 -0.73861 APTGPFK 0 0 0 9.53374 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P28290 ITPI2_HUMAN Protein ITPRID2 (Cleavage signal-1 protein) (CS-1) (ITPR-interacting domain-containing protein 2) (Ki-ras-induced actin-interacting protein) (Sperm-specific antigen 2) ITPRID2 CS1 KIAA1927 KRAP SSFA2 Homo sapiens (Human) cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] actin filament binding [GO:0051015]; signaling receptor binding [GO:0005102] 0.96324 -2.6611 LQFHQKGR 11.39 0 0 0 11.5853 0 11.7268 11.7249 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P28324 ELK4_HUMAN ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1) (SRF accessory protein 1) ELK4 SAP1 Homo sapiens (Human) histone H3 deacetylation [GO:0070932]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.92303 -1.0611 ALRYYYVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.08563 0 0 0 0 0 0 P28329 CLAT_HUMAN Choline O-acetyltransferase (CHOACTase) (ChAT) (Choline acetylase) (EC 2.3.1.6) CHAT Homo sapiens (Human) acetylcholine biosynthetic process [GO:0008292]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter transport [GO:0006836]; phosphatidylcholine biosynthetic process [GO:0006656] cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]; nucleus [GO:0005634]; synapse [GO:0045202] choline O-acetyltransferase activity [GO:0004102] 0.96804 -3.8278 ADSVSELPAPR 0 0 0 0 0 0 0 0 0 0 8.69105 0 0 0 0 0 0 0 0 0 9.64769 9.86412 0 0 0 0 0 P28330 ACADL_HUMAN "Long-chain specific acyl-CoA dehydrogenase, mitochondrial (LCAD) (EC 1.3.8.8)" ACADL Homo sapiens (Human) "carnitine catabolic process [GO:0042413]; carnitine metabolic process, CoA-linked [GO:0019254]; cellular lipid catabolic process [GO:0044242]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; long-chain fatty acid catabolic process [GO:0042758]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of fatty acid oxidation [GO:0046322]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of cholesterol metabolic process [GO:0090181]; temperature homeostasis [GO:0001659]" cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739] fatty-acyl-CoA binding [GO:0000062]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; long-chain-acyl-CoA dehydrogenase activity [GO:0004466]; palmitoyl-CoA oxidase activity [GO:0016401] 0.95939 -1.7405 ELIAREIVFDK 0 8.78149 9.08162 0 0 0 0 0 0 10.1187 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.5377 0 0 P28331 NDUS1_HUMAN "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (EC 7.1.1.2) (Complex I-75kD) (CI-75kD)" NDUFS1 Homo sapiens (Human) "aerobic respiration [GO:0009060]; apoptotic mitochondrial changes [GO:0008637]; ATP metabolic process [GO:0046034]; cellular respiration [GO:0045333]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]; reactive oxygen species metabolic process [GO:0072593]; regulation of mitochondrial membrane potential [GO:0051881]" mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrial respiratory chain complex I [GO:0005747]; mitochondrion [GO:0005739] "2 iron, 2 sulfur cluster binding [GO:0051537]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; NADH dehydrogenase (ubiquinone) activity [GO:0008137]" 0.67131 0.39378 VGMQIPR 10.4671 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.2975 0 0 0 0 0 0 0 0 0 0 0 P28332 ADH6_HUMAN Alcohol dehydrogenase 6 (EC 1.1.1.1) ADH6 Homo sapiens (Human) ethanol oxidation [GO:0006069]; response to ethanol [GO:0045471]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572] cytosol [GO:0005829]; extracellular exosome [GO:0070062] "alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; NAD-retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]" 0.88133 -0.30444 IIGVDVNKEKFK 14.4149 14.5791 14.0955 0 0 0 0 0 0 0 0 0 0 0 0 9.43734 0 0 0 0 0 0 0 0 0 0 9.79131 P28340 DPOD1_HUMAN DNA polymerase delta catalytic subunit (EC 2.7.7.7) (3'-5' exodeoxyribonuclease) (EC 3.1.11.-) (DNA polymerase subunit delta p125) POLD1 POLD Homo sapiens (Human) "base-excision repair, gap-filling [GO:0006287]; cellular response to UV [GO:0034644]; DNA biosynthetic process [GO:0071897]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication proofreading [GO:0045004]; DNA synthesis involved in DNA repair [GO:0000731]; DNA-templated DNA replication [GO:0006261]; error-free translesion synthesis [GO:0070987]; fatty acid homeostasis [GO:0055089]; nucleotide-excision repair, DNA gap filling [GO:0006297]; response to UV [GO:0009411]" aggresome [GO:0016235]; cytosol [GO:0005829]; delta DNA polymerase complex [GO:0043625]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleotide-excision repair complex [GO:0000109]; nucleus [GO:0005634] "3'-5'-DNA exonuclease activity [GO:0008296]; 4 iron, 4 sulfur cluster binding [GO:0051539]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]" 0.92694 -1.2067 DPGSAPSLGDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.53697 0 9.41519 0 0 0 0 9.72407 P28356 HXD9_HUMAN Homeobox protein Hox-D9 (Homeobox protein Hox-4C) (Homeobox protein Hox-5.2) HOXD9 HOX4C Homo sapiens (Human) adult locomotory behavior [GO:0008344]; anterior/posterior pattern specification [GO:0009952]; embryonic forelimb morphogenesis [GO:0035115]; embryonic skeletal system morphogenesis [GO:0048704]; hindlimb morphogenesis [GO:0035137]; mammary gland development [GO:0030879]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peripheral nervous system neuron development [GO:0048935]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proximal/distal pattern formation [GO:0009954]; regulation of transcription by RNA polymerase II [GO:0006357]; single fertilization [GO:0007338]; skeletal muscle tissue development [GO:0007519] chromatin [GO:0000785]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96139 -2.5603 LGGSAGR 0 0 0 8.98003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P28358 HXD10_HUMAN Homeobox protein Hox-D10 (Homeobox protein Hox-4D) (Homeobox protein Hox-4E) HOXD10 HOX4D HOX4E Homo sapiens (Human) adult locomotory behavior [GO:0008344]; anterior/posterior pattern specification [GO:0009952]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; forelimb morphogenesis [GO:0035136]; hindlimb morphogenesis [GO:0035137]; negative regulation of cell cycle [GO:0045786]; neuromuscular process [GO:0050905]; peripheral nervous system neuron development [GO:0048935]; proximal/distal pattern formation [GO:0009954]; regulation of transcription by RNA polymerase II [GO:0006357]; single fertilization [GO:0007338]; skeletal muscle tissue development [GO:0007519]; spinal cord motor neuron cell fate specification [GO:0021520] chromatin [GO:0000785]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription repressor complex [GO:0017053] "chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96294 -2.5271 GGLPEER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.91169 0 0 8.72574 0 0 0 0 0 0 0 0 P28360 MSX1_HUMAN Homeobox protein MSX-1 (Homeobox protein Hox-7) (Msh homeobox 1-like protein) MSX1 HOX7 Homo sapiens (Human) "activation of meiosis [GO:0090427]; anterior/posterior pattern specification [GO:0009952]; BMP signaling pathway involved in heart development [GO:0061312]; bone morphogenesis [GO:0060349]; cardiac conduction system development [GO:0003161]; cartilage morphogenesis [GO:0060536]; cell morphogenesis [GO:0000902]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic morphogenesis [GO:0048598]; embryonic nail plate morphogenesis [GO:0035880]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; face morphogenesis [GO:0060325]; forebrain development [GO:0030900]; in utero embryonic development [GO:0001701]; mammary gland epithelium development [GO:0061180]; mesenchymal cell apoptotic process [GO:0097152]; mesenchymal cell proliferation [GO:0010463]; midbrain development [GO:0030901]; middle ear morphogenesis [GO:0042474]; muscle organ development [GO:0007517]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of striated muscle cell differentiation [GO:0051154]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of mesenchymal cell apoptotic process [GO:2001055]; protein localization to nucleus [GO:0034504]; protein stabilization [GO:0050821]; regulation of odontogenesis [GO:0042481]; regulation of transcription by RNA polymerase II [GO:0006357]; roof of mouth development [GO:0060021]; signal transduction involved in regulation of gene expression [GO:0023019]; stem cell differentiation [GO:0048863]; transcription by RNA polymerase II [GO:0006366]" chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "cis-regulatory region sequence-specific DNA binding [GO:0000987]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; p53 binding [GO:0002039]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.74613 0.31876 TPFTTAQLLALER 0 0 9.53753 0 0 0 0 0 0 12.562 0 12.6352 10.1032 0 0 10.4086 0 10.092 0 0 0 0 0 0 0 0 0 P28476 GBRR2_HUMAN Gamma-aminobutyric acid receptor subunit rho-2 (GABA(A) receptor subunit rho-2) (GABA(C) receptor) GABRR2 Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid signaling pathway [GO:0007214]; monoatomic ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165]; visual perception [GO:0007601] chloride channel complex [GO:0034707]; GABA-A receptor complex [GO:1902711]; GABA-ergic synapse [GO:0098982]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202] chloride channel activity [GO:0005254]; GABA-A receptor activity [GO:0004890]; neurotransmitter receptor activity [GO:0030594]; protein domain specific binding [GO:0019904]; transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315] 0.96182 -2.6102 LYINFTLR 0 0 0 0 0 0 9.67119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P28482 MK01_HUMAN Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) MAPK1 ERK2 PRKM1 PRKM2 Homo sapiens (Human) androgen receptor signaling pathway [GO:0030521]; apoptotic process [GO:0006915]; B cell receptor signaling pathway [GO:0050853]; Bergmann glial cell differentiation [GO:0060020]; cardiac neural crest cell development involved in heart development [GO:0061308]; caveolin-mediated endocytosis [GO:0072584]; cell cycle [GO:0007049]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid starvation [GO:0034198]; cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; cellular response to tumor necrosis factor [GO:0071356]; chemical synaptic transmission [GO:0007268]; chemotaxis [GO:0006935]; cytosine metabolic process [GO:0019858]; DNA damage response [GO:0006974]; ERBB signaling pathway [GO:0038127]; ERK1 and ERK2 cascade [GO:0070371]; face development [GO:0060324]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; intracellular signal transduction [GO:0035556]; labyrinthine layer blood vessel development [GO:0060716]; learning or memory [GO:0007611]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; long-term synaptic potentiation [GO:0060291]; lung morphogenesis [GO:0060425]; mammary gland epithelial cell proliferation [GO:0033598]; negative regulation of cell differentiation [GO:0045596]; outer ear morphogenesis [GO:0042473]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of macrophage proliferation [GO:0120041]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; progesterone receptor signaling pathway [GO:0050847]; protein phosphorylation [GO:0006468]; regulation of cellular pH [GO:0030641]; regulation of cytoskeleton organization [GO:0051493]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of Golgi inheritance [GO:0090170]; regulation of ossification [GO:0030278]; regulation of protein stability [GO:0031647]; regulation of stress-activated MAPK cascade [GO:0032872]; response to epidermal growth factor [GO:0070849]; response to exogenous dsRNA [GO:0043330]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; steroid hormone mediated signaling pathway [GO:0043401]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; trachea formation [GO:0060440] azurophil granule lumen [GO:0035578]; caveola [GO:0005901]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; microtubule organizing center [GO:0005815]; mitochondrion [GO:0005739]; mitotic spindle [GO:0072686]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]; synapse [GO:0045202] ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; MAP kinase activity [GO:0004707]; MAP kinase kinase activity [GO:0004708]; phosphatase binding [GO:0019902]; phosphotyrosine residue binding [GO:0001784]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353] 0 2.7944 AAAAAAGAGPEMVR 0 0 0 0 0 0 0 0 0 9.50514 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P28562 DUS1_HUMAN Dual specificity protein phosphatase 1 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase hVH1) (Mitogen-activated protein kinase phosphatase 1) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase CL100) DUSP1 CL100 MKP1 PTPN10 VH1 Homo sapiens (Human) cell cycle [GO:0007049]; cellular response to chemokine [GO:1990869]; endoderm formation [GO:0001706]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of meiotic cell cycle [GO:0051447]; negative regulation of monocyte chemotaxis [GO:0090027]; negative regulation of p38MAPK cascade [GO:1903753]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation [GO:0035335]; regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090266] cytoplasm [GO:0005737]; nucleus [GO:0005634] MAP kinase tyrosine phosphatase activity [GO:0033550]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; mitogen-activated protein kinase binding [GO:0051019]; myosin phosphatase activity [GO:0017018]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine/threonine phosphatase activity [GO:0008330] 0.65727 0.39512 GGYEAFSASCPELCSK 12.6455 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.61045 0 0 0 0 0 0 0 0 0 P28698 MZF1_HUMAN Myeloid zinc finger 1 (MZF-1) (Zinc finger and SCAN domain-containing protein 6) (Zinc finger protein 42) MZF1 MZF ZNF42 ZSCAN6 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355] nucleoplasm [GO:0005654] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; transcription cis-regulatory region binding [GO:0000976]" 0.91784 -0.8688 LEEHRRVHTGEQPFR 0 0 0 0 0 0 0 0 11.7816 0 0 0 0 0 0 0 0 0 0 10.2825 0 0 0 0 0 0 0 P28702 RXRB_HUMAN Retinoic acid receptor RXR-beta (Nuclear receptor subfamily 2 group B member 2) (Retinoid X receptor beta) RXRB NR2B2 Homo sapiens (Human) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; hormone-mediated signaling pathway [GO:0009755]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of bone mineralization [GO:0030501]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vitamin D receptor signaling pathway [GO:0070564]; response to retinoic acid [GO:0032526]; retinoic acid receptor signaling pathway [GO:0048384] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; nuclear receptor activity [GO:0004879]; nuclear steroid receptor activity [GO:0003707]; retinoic acid-responsive element binding [GO:0044323]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]; zinc ion binding [GO:0008270]" 0.96989 -5.2862 EKVYASLETYCK 0 0 0 0 0 9.36372 0 0 10.4458 0 0 0 0 0 0 0 0 10.6238 0 0 0 0 0 0 0 0 0 P28715 ERCC5_HUMAN DNA excision repair protein ERCC-5 (EC 3.1.-.-) (DNA repair protein complementing XP-G cells) (Xeroderma pigmentosum group G-complementing protein) ERCC5 ERCM2 XPG XPGC Homo sapiens (Human) "base-excision repair, AP site formation [GO:0006285]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of apoptotic process [GO:0043066]; nucleotide-excision repair [GO:0006289]; regulation of catalytic activity [GO:0050790]; response to UV [GO:0009411]; response to UV-C [GO:0010225]; transcription-coupled nucleotide-excision repair [GO:0006283]" chromosome [GO:0005694]; nucleoplasm [GO:0005654]; nucleotide-excision repair complex [GO:0000109]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] bubble DNA binding [GO:0000405]; damaged DNA binding [GO:0003684]; DNA endonuclease activity [GO:0004520]; double-stranded DNA binding [GO:0003690]; endonuclease activity [GO:0004519]; enzyme activator activity [GO:0008047]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; RNA polymerase II complex binding [GO:0000993]; single-stranded DNA binding [GO:0003697] 0.96769 -2.8987 GVQGLWKLLECSGR 0 0 0 0 0 0 0 0 10.9538 0 0 0 0 0 0 0 0 0 0 0 9.90908 0 0 0 12.5799 0 0 P28749 RBL1_HUMAN Retinoblastoma-like protein 1 (107 kDa retinoblastoma-associated protein) (p107) (pRb1) RBL1 Homo sapiens (Human) cell cycle [GO:0007049]; cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; negative regulation of cellular senescence [GO:2000773]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of lipid kinase activity [GO:0043550] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; transcription regulator complex [GO:0005667] promoter-specific chromatin binding [GO:1990841]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977] 0.96984 -4.3315 DINNMIRQGEQRTK 0 0 0 0 10.691 8.55055 0 0 0 0 8.83826 0 0 10.9268 0 0 0 9.50383 0 0 0 0 0 0 10.8041 0 0 P28827 PTPRM_HUMAN Receptor-type tyrosine-protein phosphatase mu (Protein-tyrosine phosphatase mu) (R-PTP-mu) (EC 3.1.3.48) PTPRM PTPRL1 Homo sapiens (Human) cytoplasmic sequestering of protein [GO:0051220]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; neuron projection development [GO:0031175]; protein dephosphorylation [GO:0006470]; response to xenobiotic stimulus [GO:0009410]; retina layer formation [GO:0010842]; retinal ganglion cell axon guidance [GO:0031290]; signal transduction [GO:0007165] adherens junction [GO:0005912]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; intracellular non-membrane-bounded organelle [GO:0043232]; lamellipodium [GO:0030027]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001] 0.92302 -1.0607 DENRMKNR 0 0 0 0 0 0 0 0 0 10.3121 0 0 0 0 0 0 0 0 0 0 0 9.79534 0 0 0 0 9.72984 P28908 TNR8_HUMAN Tumor necrosis factor receptor superfamily member 8 (CD30L receptor) (Ki-1 antigen) (Lymphocyte activation antigen CD30) (CD antigen CD30) TNFRSF8 CD30 D1S166E Homo sapiens (Human) cellular response to mechanical stimulus [GO:0071260]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of apoptotic process [GO:0043065]; positive regulation of TRAIL production [GO:0032759]; positive regulation of tumor necrosis factor production [GO:0032760]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] transmembrane signaling receptor activity [GO:0004888] 0.93969 -1.3247 AVRRCCYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.60203 0 0 0 0 P29016 CD1B_HUMAN T-cell surface glycoprotein CD1b (CD antigen CD1b) CD1B Homo sapiens (Human) "adaptive immune response [GO:0002250]; antigen processing and presentation, endogenous lipid antigen via MHC class Ib [GO:0048006]; antigen processing and presentation, exogenous lipid antigen via MHC class Ib [GO:0048007]; immune response [GO:0006955]; positive regulation of T cell mediated cytotoxicity [GO:0001916]" cell surface [GO:0009986]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886] endogenous lipid antigen binding [GO:0030883]; exogenous lipid antigen binding [GO:0030884]; lipopeptide binding [GO:0071723] 0.91404 -0.77851 VKHSSLEGQDIILYWR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.7578 0 0 0 0 0 0 0 0 0 P29034 S10A2_HUMAN Protein S100-A2 (CAN19) (Protein S-100L) (S100 calcium-binding protein A2) S100A2 S100L Homo sapiens (Human) endothelial cell migration [GO:0043542] calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914] 0.9544 -1.5222 YSCQEGDKFK 0 0 0 0 0 0 0 0 0 0 8.93767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P29074 PTN4_HUMAN Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (MEG) (PTPase-MEG1) PTPN4 Homo sapiens (Human) peptidyl-tyrosine phosphorylation [GO:0018108]; protein dephosphorylation [GO:0006470] cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; nucleoplasm [GO:0005654] cytoskeletal protein binding [GO:0008092]; glutamate receptor binding [GO:0035254]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; protein tyrosine phosphatase activity [GO:0004725] 0.96314 -2.1912 ACKNLWK 0 0 0 0 0 0 0 0 0 0 0 10.8211 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P29084 T2EB_HUMAN Transcription initiation factor IIE subunit beta (TFIIE-beta) (General transcription factor IIE subunit 2) GTF2E2 TF2E2 Homo sapiens (Human) transcription by RNA polymerase II [GO:0006366]; transcription initiation at RNA polymerase II promoter [GO:0006367] cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIE complex [GO:0005673] DNA binding [GO:0003677]; RNA binding [GO:0003723]; RNA polymerase II general transcription initiation factor activity [GO:0016251] 0.96886 -4.5467 IEEYLKR 14.1349 13.8237 13.9878 0 0 0 14.467 14.5661 14.424 14.8137 14.659 14.5881 0 0 13.2498 12.6491 12.8157 0 0 0 10.1163 0 0 0 0 0 9.09077 P29120 NEC1_HUMAN Neuroendocrine convertase 1 (NEC 1) (EC 3.4.21.93) (Prohormone convertase 1) (Proprotein convertase 1) (PC1) PCSK1 NEC1 Homo sapiens (Human) cell-cell signaling [GO:0007267]; insulin processing [GO:0030070]; neurogenesis [GO:0022008]; pancreas development [GO:0031016]; peptide biosynthetic process [GO:0043043]; pituitary gland development [GO:0021983]; positive regulation of protein secretion [GO:0050714]; protein autoprocessing [GO:0016540]; protein processing [GO:0016485]; proteolysis [GO:0006508]; response to axon injury [GO:0048678]; response to calcium ion [GO:0051592]; response to chlorate [GO:0010157]; response to fatty acid [GO:0070542]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; response to morphine [GO:0043278]; response to nutrient levels [GO:0031667]; response to peptide hormone [GO:0043434]; response to xenobiotic stimulus [GO:0009410] axon terminus [GO:0043679]; dendrite [GO:0030425]; extracellular space [GO:0005615]; membrane [GO:0016020]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]; secretory granule lumen [GO:0034774]; trans-Golgi network [GO:0005802]; transport vesicle [GO:0030133] identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252] 0.96263 -2.6312 ITDMSGRIQNEGRIVNWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.73162 0 0 0 0 0 0 0 0 0 10.1746 10.9474 11.1651 P29122 PCSK6_HUMAN Proprotein convertase subtilisin/kexin type 6 (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin-like proprotein convertase 4) (SPC4) (Subtilisin/kexin-like protease PACE4) PCSK6 PACE4 Homo sapiens (Human) "determination of left/right symmetry [GO:0007368]; glycoprotein metabolic process [GO:0009100]; nerve growth factor production [GO:0032902]; peptide hormone processing [GO:0016486]; protein processing [GO:0016485]; regulation of BMP signaling pathway [GO:0030510]; regulation of lipoprotein lipase activity [GO:0051004]; secretion by cell [GO:0032940]; zygotic determination of anterior/posterior axis, embryo [GO:0007354]" cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; membrane [GO:0016020]; plasma membrane [GO:0005886] endopeptidase activity [GO:0004175]; heparin binding [GO:0008201]; nerve growth factor binding [GO:0048406]; serine-type endopeptidase activity [GO:0004252] 0.96401 -2.3843 CDENCLSCAGSSR 0 10.4315 0 0 0 0 0 10.5461 0 11.0337 11.0014 0 0 0 0 0 0 0 0 0 0 0 9.29471 8.82305 0 0 0 P29144 TPP2_HUMAN Tripeptidyl-peptidase 2 (TPP-2) (EC 3.4.14.10) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase II) (TPP-II) TPP2 Homo sapiens (Human) intracellular amino acid homeostasis [GO:0080144]; protein polyubiquitination [GO:0000209]; proteolysis [GO:0006508] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654] aminopeptidase activity [GO:0004177]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; tripeptidyl-peptidase activity [GO:0008240] 0.91913 -0.89726 AYDYLVQNTSFANK 0 0 10.4945 0 0 9.26728 0 0 0 0 0 0 0 12.1842 12.3389 0 12.8455 0 0 10.1434 0 0 8.95913 9.58387 0 0 0 P29274 AA2AR_HUMAN Adenosine receptor A2a ADORA2A ADORA2 Homo sapiens (Human) "adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; astrocyte activation [GO:0048143]; blood circulation [GO:0008015]; blood coagulation [GO:0007596]; cell-cell signaling [GO:0007267]; cellular defense response [GO:0006968]; central nervous system development [GO:0007417]; eating behavior [GO:0042755]; excitatory postsynaptic potential [GO:0060079]; G protein-coupled adenosine receptor signaling pathway [GO:0001973]; inflammatory response [GO:0006954]; inhibitory postsynaptic potential [GO:0060080]; locomotory behavior [GO:0007626]; membrane depolarization [GO:0051899]; negative regulation of alpha-beta T cell activation [GO:0046636]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of inflammatory response [GO:0050728]; negative regulation of locomotion [GO:0040013]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of vascular permeability [GO:0043116]; neuron projection morphogenesis [GO:0048812]; phagocytosis [GO:0006909]; positive regulation of acetylcholine secretion, neurotransmission [GO:0014057]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of protein secretion [GO:0050714]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of urine volume [GO:0035810]; prepulse inhibition [GO:0060134]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of calcium ion transport [GO:0051924]; regulation of DNA-templated transcription [GO:0006355]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of norepinephrine secretion [GO:0014061]; response to amphetamine [GO:0001975]; response to caffeine [GO:0031000]; response to inorganic substance [GO:0010035]; response to purine-containing compound [GO:0014074]; response to xenobiotic stimulus [GO:0009410]; sensory perception [GO:0007600]; synaptic transmission, cholinergic [GO:0007271]; synaptic transmission, dopaminergic [GO:0001963]; synaptic transmission, glutamatergic [GO:0035249]; vasodilation [GO:0042311]" axolemma [GO:0030673]; dendrite [GO:0030425]; endomembrane system [GO:0012505]; glutamatergic synapse [GO:0098978]; intermediate filament [GO:0005882]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynaptic active zone [GO:0048786]; presynaptic membrane [GO:0042734] alpha-actinin binding [GO:0051393]; enzyme binding [GO:0019899]; G protein-coupled adenosine receptor activity [GO:0001609]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; protein-containing complex binding [GO:0044877]; type 5 metabotropic glutamate receptor binding [GO:0031802] 0.6783 0.39371 AAGTSAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.15785 0 0 0 P29279 CCN2_HUMAN CCN family member 2 (Cellular communication network factor 2) (Connective tissue growth factor) (Hypertrophic chondrocyte-specific protein 24) (Insulin-like growth factor-binding protein 8) (IBP-8) (IGF-binding protein 8) (IGFBP-8) CCN2 CTGF HCS24 IGFBP8 Homo sapiens (Human) aging [GO:0007568]; angiogenesis [GO:0001525]; calcium ion transmembrane import into cytosol [GO:0097553]; cartilage condensation [GO:0001502]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; chondrocyte differentiation [GO:0002062]; chondrocyte proliferation [GO:0035988]; DNA biosynthetic process [GO:0071897]; epidermis development [GO:0008544]; extracellular matrix constituent secretion [GO:0070278]; fibroblast growth factor receptor signaling pathway [GO:0008543]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; lung development [GO:0030324]; negative regulation of cell death [GO:0060548]; negative regulation of gene expression [GO:0010629]; ossification [GO:0001503]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of cell activation [GO:0050867]; positive regulation of cell death [GO:0010942]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of G0 to G1 transition [GO:0070318]; positive regulation of gene expression [GO:0010628]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of stress fiber assembly [GO:0051496]; reactive oxygen species metabolic process [GO:0072593]; regulation of chondrocyte differentiation [GO:0032330]; response to amino acid [GO:0043200]; response to anoxia [GO:0034059]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to glucose [GO:0009749]; response to mineralocorticoid [GO:0051385]; response to peptide hormone [GO:0043434]; response to wounding [GO:0009611]; signal transduction [GO:0007165]; tissue homeostasis [GO:0001894] cell cortex [GO:0005938]; cis-Golgi network [GO:0005801]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; insulin-like growth factor binding [GO:0005520]; integrin binding [GO:0005178] 0.96313 -2.1904 KNMMFIK 0 0 9.32811 0 0 0 0 0 0 0 9.41157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P29320 EPHA3_HUMAN Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1) EPHA3 ETK ETK1 HEK TYRO4 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to retinoic acid [GO:0071300]; ephrin receptor signaling pathway [GO:0048013]; fasciculation of motor neuron axon [GO:0097156]; fasciculation of sensory neuron axon [GO:0097155]; negative regulation of endocytosis [GO:0045806]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of focal adhesion assembly [GO:0051893]; regulation of GTPase activity [GO:0043087]; regulation of microtubule cytoskeleton organization [GO:0070507] actin cytoskeleton [GO:0015629]; cytosol [GO:0005829]; dendrite [GO:0030425]; early endosome [GO:0005769]; extracellular region [GO:0005576]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; ephrin receptor activity [GO:0005003]; GPI-linked ephrin receptor activity [GO:0005004]; transmembrane-ephrin receptor activity [GO:0005005] 0.95392 -1.5229 ALDGNMKCAK 0 0 0 9.32164 0 8.95364 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P29322 EPHA8_HUMAN Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) (EPH-like kinase 3) (EK3) (hEK3) (Tyrosine-protein kinase receptor EEK) EPHA8 EEK HEK3 KIAA1459 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; ephrin receptor signaling pathway [GO:0048013]; neuron projection development [GO:0031175]; neuron remodeling [GO:0016322]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein autophosphorylation [GO:0046777]; regulation of cell adhesion [GO:0030155]; regulation of cell adhesion mediated by integrin [GO:0033628]; substrate-dependent cell migration [GO:0006929] dendrite [GO:0030425]; early endosome membrane [GO:0031901]; neuron projection [GO:0043005]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; GPI-linked ephrin receptor activity [GO:0005004]; growth factor binding [GO:0019838]; transmembrane-ephrin receptor activity [GO:0005005] 0.32513 0.78476 AFQDSDEEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.17899 0 0 0 0 8.47013 9.46179 0 0 0 0 P29323 EPHB2_HUMAN Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) (ELK-related tyrosine kinase) (EPH tyrosine kinase 3) (EPH-like kinase 5) (EK5) (hEK5) (Renal carcinoma antigen NY-REN-47) (Tyrosine-protein kinase TYRO5) (Tyrosine-protein kinase receptor EPH-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2] EPHB2 DRT EPHT3 EPTH3 ERK HEK5 TYRO5 Homo sapiens (Human) "angiogenesis [GO:0001525]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; B cell activation [GO:0042113]; camera-type eye morphogenesis [GO:0048593]; cellular response to amyloid-beta [GO:1904646]; cellular response to lipopolysaccharide [GO:0071222]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; hindbrain tangential cell migration [GO:0021934]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; nervous system development [GO:0007399]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell migration [GO:0030335]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of tumor necrosis factor production [GO:0032760]; postsynaptic membrane assembly [GO:0097104]; regulation of autophagosome assembly [GO:2000785]; regulation of behavioral fear response [GO:2000822]; regulation of blood coagulation [GO:0030193]; regulation of body fluid levels [GO:0050878]; regulation of filopodium assembly [GO:0051489]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; regulation of T-helper 17 type immune response [GO:2000316]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; tight junction assembly [GO:0120192]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; urogenital system development [GO:0001655]; vesicle-mediated intercellular transport [GO:0110077]" axon [GO:0030424]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734] amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; transmembrane-ephrin receptor activity [GO:0005005] 0.96453 -2.3991 ARTVAGYGRYSGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1387 0 0 0 0 0 0 11.8112 10.4688 P29350 PTN6_HUMAN Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Protein-tyrosine phosphatase SHP-1) (SH-PTP1) PTPN6 HCP PTP1C Homo sapiens (Human) B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; epididymis development [GO:1905867]; G protein-coupled receptor signaling pathway [GO:0007186]; hematopoietic progenitor cell differentiation [GO:0002244]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; megakaryocyte development [GO:0035855]; mitotic cell cycle [GO:0000278]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002924]; negative regulation of inflammatory response to wounding [GO:0106015]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of mast cell activation involved in immune response [GO:0033007]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of tumor necrosis factor production [GO:0032720]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; protein dephosphorylation [GO:0006470]; regulation of apoptotic process [GO:0042981]; regulation of B cell differentiation [GO:0045577]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]; T cell proliferation [GO:0042098]; T cell receptor signaling pathway [GO:0050852] alpha-beta T cell receptor complex [GO:0042105]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724] cell adhesion molecule binding [GO:0050839]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; phosphorylation-dependent protein binding [GO:0140031]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein serine/threonine kinase inhibitor activity [GO:0030291]; protein tyrosine phosphatase activity [GO:0004725]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001] 0.95889 -1.8655 GVHGSFLARPSR 0 0 0 0 0 9.55013 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1833 0 0 9.41119 0 0 0 P29353 SHC1_HUMAN SHC-transforming protein 1 (SHC-transforming protein 3) (SHC-transforming protein A) (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1) SHC1 SHC SHCA Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; angiogenesis [GO:0001525]; cell-cell adhesion [GO:0098609]; cellular response to growth factor stimulus [GO:0071363]; defense response to bacterium [GO:0042742]; epidermal growth factor receptor signaling pathway [GO:0007173]; heart development [GO:0007507]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; intracellular signal transduction [GO:0035556]; negative regulation of angiogenesis [GO:0016525]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation in bone marrow [GO:0071864]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of superoxide metabolic process [GO:0090322] cytosol [GO:0005829]; focal adhesion [GO:0005925]; mitochondrial matrix [GO:0005759]; plasma membrane [GO:0005886]; Shc-EGFR complex [GO:0070435] ephrin receptor binding [GO:0046875]; epidermal growth factor binding [GO:0048408]; epidermal growth factor receptor binding [GO:0005154]; insulin receptor binding [GO:0005158]; insulin-like growth factor receptor binding [GO:0005159]; molecular function activator activity [GO:0140677]; neurotrophin TRKA receptor binding [GO:0005168]; phospholipid binding [GO:0005543]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068] 0.92487 -0.98481 GWLHPNDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.05009 0 0 9.83476 8.72833 9.56341 8.24332 9.25722 9.27968 0 0 0 8.66306 P29371 NK3R_HUMAN Neuromedin-K receptor (NKR) (NK-3 receptor) (NK-3R) (Neurokinin B receptor) (Tachykinin receptor 3) TACR3 NK3R TAC3R Homo sapiens (Human) aging [GO:0007568]; hyperosmotic salinity response [GO:0042538]; positive regulation of blood pressure [GO:0045777]; positive regulation of flagellated sperm motility [GO:1902093]; positive regulation of heart rate [GO:0010460]; positive regulation of uterine smooth muscle contraction [GO:0070474]; regulation of dopamine metabolic process [GO:0042053]; regulation of feeding behavior [GO:0060259]; response to cocaine [GO:0042220]; response to estradiol [GO:0032355]; response to morphine [GO:0043278]; tachykinin receptor signaling pathway [GO:0007217] cytoplasm [GO:0005737]; dendrite membrane [GO:0032590]; neuronal cell body membrane [GO:0032809]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sperm midpiece [GO:0097225] tachykinin receptor activity [GO:0004995] 0.90638 -0.7125 TLCFVQWPEGPK 0 0 0 0 0 0 0 0 9.62706 0 0 0 0 9.91132 0 0 0 0 0 0 0 0 0 0 0 0 0 P29373 RABP2_HUMAN Cellular retinoic acid-binding protein 2 (Cellular retinoic acid-binding protein II) (CRABP-II) CRABP2 Homo sapiens (Human) embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; fatty acid transport [GO:0015908]; positive regulation of collateral sprouting [GO:0048672]; regulation of DNA-templated transcription [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] cyclin binding [GO:0030332]; fatty acid binding [GO:0005504]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841] 0.009828 1.8225 QEGDTFYIK 0 0 0 0 0 0 0 0 0 10.636 10.5917 9.08579 0 10.0111 0 0 0 0 0 0 0 0 0 0 0 0 0 P29375 KDM5A_HUMAN Lysine-specific demethylase 5A (EC 1.14.11.67) (Histone demethylase JARID1A) (Jumonji/ARID domain-containing protein 1A) (Retinoblastoma-binding protein 2) (RBBP-2) ([histone H3]-trimethyl-L-lysine(4) demethylase 5A) KDM5A JARID1A RBBP2 RBP2 Homo sapiens (Human) chromatin remodeling [GO:0006338]; circadian regulation of gene expression [GO:0032922]; facultative heterochromatin formation [GO:0140718]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-binding transcription factor activity [GO:0051090] nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993] chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; enzyme inhibitor activity [GO:0004857]; histone binding [GO:0042393]; histone demethylase activity [GO:0032452]; histone H3K4me/H3K4me2/H3K4me3 demethylase activity [GO:0034647]; methylated histone binding [GO:0035064]; transcription cis-regulatory region binding [GO:0000976]; transcription coactivator activity [GO:0003713]; zinc ion binding [GO:0008270] 0.9678 -3.6701 MTMVDRIEEVKFCICR 0 10.037 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0674 0 0 9.20293 0 0 0 0 0 P29400 CO4A5_HUMAN Collagen alpha-5(IV) chain COL4A5 Homo sapiens (Human) collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; extracellular matrix organization [GO:0030198]; neuromuscular junction development [GO:0007528] basement membrane [GO:0005604]; collagen type IV trimer [GO:0005587]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594] extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020] 0.80523 0.23644 GLQGEQGVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8577 0 0 0 0 0 0 0 0 0 0 P29401 TKT_HUMAN Transketolase (TK) (EC 2.2.1.1) TKT Homo sapiens (Human) "glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; regulation of growth [GO:0040008]; ribose phosphate biosynthetic process [GO:0046390]; xylulose 5-phosphate biosynthetic process [GO:1901159]" cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; peroxisome [GO:0005777]; vesicle [GO:0031982] calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802] 0 26.726 AVELAANTK 9.68324 9.4457 10.2257 0 0 0 11.6687 11.3445 11.1699 9.93893 10.7969 10.5799 0 0 0 11.4711 11.0845 11.2795 0 11.233 10.51 0 10.4971 0 0 0 8.36374 P29474 NOS3_HUMAN "Nitric oxide synthase 3 (EC 1.14.13.39) (Constitutive NOS) (cNOS) (EC-NOS) (NOS type III) (NOSIII) (Nitric oxide synthase, endothelial) (Endothelial NOS) (eNOS)" NOS3 Homo sapiens (Human) angiogenesis [GO:0001525]; aortic valve morphogenesis [GO:0003180]; arginine catabolic process [GO:0006527]; blood vessel diameter maintenance [GO:0097746]; blood vessel remodeling [GO:0001974]; calcium ion transport [GO:0006816]; cell redox homeostasis [GO:0045454]; endocardial cushion morphogenesis [GO:0003203]; endothelial cell migration [GO:0043542]; establishment of localization in cell [GO:0051649]; homeostasis of number of cells within a tissue [GO:0048873]; in utero embryonic development [GO:0001701]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lung development [GO:0030324]; mitochondrion organization [GO:0007005]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of blood pressure [GO:0045776]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of hydrolase activity [GO:0051346]; negative regulation of muscle hyperplasia [GO:0014740]; negative regulation of platelet activation [GO:0010544]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of smooth muscle cell proliferation [GO:0048662]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; ovulation from ovarian follicle [GO:0001542]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of gene expression [GO:0010628]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of Notch signaling pathway [GO:0045747]; potassium ion transport [GO:0006813]; pulmonary valve morphogenesis [GO:0003184]; regulation of blood pressure [GO:0008217]; regulation of nervous system process [GO:0031644]; regulation of sodium ion transport [GO:0002028]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of the force of heart contraction by chemical signal [GO:0003057]; removal of superoxide radicals [GO:0019430]; response to fluid shear stress [GO:0034405]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to lipopolysaccharide [GO:0032496]; smooth muscle hyperplasia [GO:0014806]; vasodilation [GO:0042311]; ventricular septum morphogenesis [GO:0060412] caveola [GO:0005901]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506] actin monomer binding [GO:0003785]; arginine binding [GO:0034618]; cadmium ion binding [GO:0046870]; calmodulin binding [GO:0005516]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; NADP binding [GO:0050661]; nitric-oxide synthase activity [GO:0004517]; scaffold protein binding [GO:0097110]; tetrahydrobiopterin binding [GO:0034617] 0.96942 -4.6581 CVGRIQWGK 0 0 0 0 0 0 0 0 0 0 0 9.36704 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7126 P29475 NOS1_HUMAN "Nitric oxide synthase 1 (EC 1.14.13.39) (Constitutive NOS) (NC-NOS) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Nitric oxide synthase, brain) (bNOS) (Peptidyl-cysteine S-nitrosylase NOS1)" NOS1 Homo sapiens (Human) arginine catabolic process [GO:0006527]; cell redox homeostasis [GO:0045454]; cellular response to growth factor stimulus [GO:0071363]; multicellular organismal response to stress [GO:0033555]; muscle contraction [GO:0006936]; myoblast fusion [GO:0007520]; negative regulation of blood pressure [GO:0045776]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of calcium ion transport into cytosol [GO:0010523]; negative regulation of hydrolase activity [GO:0051346]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of serotonin uptake [GO:0051612]; neurotransmitter biosynthetic process [GO:0042136]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of histone acetylation [GO:0035066]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of sodium ion transmembrane transport [GO:1902307]; positive regulation of the force of heart contraction [GO:0098735]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1902514]; regulation of cardiac muscle contraction [GO:0055117]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of sodium ion transport [GO:0002028]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; retrograde trans-synaptic signaling by nitric oxide [GO:0098924]; striated muscle contraction [GO:0006941]; vasodilation [GO:0042311]; xenobiotic catabolic process [GO:0042178] cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; sarcoplasmic reticulum [GO:0016529]; synapse [GO:0045202]; vesicle membrane [GO:0012506] arginine binding [GO:0034618]; cadmium ion binding [GO:0046870]; calcium-dependent protein binding [GO:0048306]; calmodulin binding [GO:0005516]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; NADP binding [GO:0050661]; nitric-oxide synthase activity [GO:0004517]; scaffold protein binding [GO:0097110]; sodium channel regulator activity [GO:0017080]; tetrahydrobiopterin binding [GO:0034617]; transmembrane transporter binding [GO:0044325] 0.97001 -5.037 DMGIQVDRDLDGK 0 0 0 0 0 9.16068 0 0 0 0 0 9.58959 0 0 0 9.83736 9.99859 0 0 0 0 0 0 0 9.67642 0 0 P29508 SPB3_HUMAN Serpin B3 (Protein T4-A) (Squamous cell carcinoma antigen 1) (SCCA-1) SERPINB3 SCCA SCCA1 Homo sapiens (Human) autocrine signaling [GO:0035425]; negative regulation of catalytic activity [GO:0043086]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; paracrine signaling [GO:0038001]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endopeptidase activity [GO:0010950]; positive regulation of epithelial to mesenchymal transition [GO:0010718] azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982] cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]; serine-type endopeptidase inhibitor activity [GO:0004867]; virus receptor activity [GO:0001618] 0 4.6288 MNSLSEANTK 0 0 0 0 0 0 0 0 0 10.4893 14.8288 9.31927 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P29536 LMOD1_HUMAN "Leiomodin-1 (64 kDa autoantigen 1D) (64 kDa autoantigen 1D3) (64 kDa autoantigen D1) (Leiomodin, muscle form) (Smooth muscle leiomodin) (SM-Lmod) (Thyroid-associated ophthalmopathy autoantigen)" LMOD1 Homo sapiens (Human) actin nucleation [GO:0045010]; muscle contraction [GO:0006936]; myofibril assembly [GO:0030239]; pointed-end actin filament capping [GO:0051694]; positive regulation of actin filament polymerization [GO:0030838] actin filament [GO:0005884]; cytosol [GO:0005829]; membrane [GO:0016020]; myofibril [GO:0030016]; sarcomere [GO:0030017] actin binding [GO:0003779]; tropomyosin binding [GO:0005523] 0.88404 -0.14027 HICGGKTEMEIAKLLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0637 0 0 0 0 0 0 0 0 0 0 0 P29590 PML_HUMAN Protein PML (E3 SUMO-protein ligase PML) (EC 2.3.2.-) (Promyelocytic leukemia protein) (RING finger protein 71) (RING-type E3 SUMO transferase PML) (Tripartite motif-containing protein 19) (TRIM19) PML MYL PP8675 RNF71 TRIM19 Homo sapiens (Human) "activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell fate commitment [GO:0045165]; cellular response to interleukin-4 [GO:0071353]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular senescence [GO:0090398]; circadian regulation of gene expression [GO:0032922]; common-partner SMAD protein phosphorylation [GO:0007182]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; entrainment of circadian clock by photoperiod [GO:0043153]; extrinsic apoptotic signaling pathway [GO:0097191]; fibroblast migration [GO:0010761]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; maintenance of protein location in nucleus [GO:0051457]; myeloid cell differentiation [GO:0030099]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of translation in response to oxidative stress [GO:0032938]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; oncogene-induced cell senescence [GO:0090402]; PML body organization [GO:0030578]; positive regulation of apoptotic process involved in mammary gland involution [GO:0060058]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of peptidyl-lysine acetylation [GO:2000758]; positive regulation of protein localization to chromosome, telomeric region [GO:1904816]; positive regulation of signal transduction by p53 class mediator [GO:1901798]; positive regulation of telomere maintenance [GO:0032206]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein import into nucleus [GO:0006606]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; protein targeting [GO:0006605]; protein-containing complex assembly [GO:0065003]; protein-containing complex localization [GO:0031503]; regulation of calcium ion transport into cytosol [GO:0010522]; regulation of cell adhesion [GO:0030155]; regulation of cell cycle [GO:0051726]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-templated transcription [GO:0006355]; regulation of double-strand break repair [GO:2000779]; response to cytokine [GO:0034097]; response to gamma radiation [GO:0010332]; response to hypoxia [GO:0001666]; response to UV [GO:0009411]; retinoic acid receptor signaling pathway [GO:0048384]; suppression of viral release by host [GO:0044790]; transforming growth factor beta receptor signaling pathway [GO:0007179]" "chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; extrinsic component of endoplasmic reticulum membrane [GO:0042406]; heterochromatin [GO:0000792]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]" cobalt ion binding [GO:0050897]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SMAD binding [GO:0046332]; SUMO binding [GO:0032183]; SUMO transferase activity [GO:0019789]; sumo-dependent protein binding [GO:0140037]; transcription coactivator activity [GO:0003713]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase activity [GO:0061659]; zinc ion binding [GO:0008270] 0.96394 -2.2463 LRQEEPQSLQAAVR 0 0 10.8549 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0243 0 0 0 0 8.88356 0 0 0 0 0 P29597 TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2) TYK2 Homo sapiens (Human) cell differentiation [GO:0030154]; cellular response to virus [GO:0098586]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; interleukin-12-mediated signaling pathway [GO:0035722]; intracellular signal transduction [GO:0035556]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 17 type immune response [GO:2000318]; positive regulation of type II interferon production [GO:0032729]; protein phosphorylation [GO:0006468]; receptor signaling pathway via JAK-STAT [GO:0007259]; type I interferon-mediated signaling pathway [GO:0060337]; type II interferon-mediated signaling pathway [GO:0060333]; type III interferon-mediated signaling pathway [GO:0038196] cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of plasma membrane [GO:0019897]; interleukin-12 receptor complex [GO:0042022]; interleukin-23 receptor complex [GO:0072536]; nucleus [GO:0005634] ATP binding [GO:0005524]; cytokine receptor binding [GO:0005126]; growth hormone receptor binding [GO:0005131]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein tyrosine kinase activity [GO:0004713]; type 1 angiotensin receptor binding [GO:0031702] 0.92189 -1.1226 EEGSSGSSGRNPQASLFGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1662 0 0 0 0 0 0 9.51406 0 0 0 10.5619 P29692 EF1D_HUMAN Elongation factor 1-delta (EF-1-delta) (Antigen NY-CO-4) EEF1D EF1D Homo sapiens (Human) cellular response to ionizing radiation [GO:0071479]; mRNA transcription [GO:0009299]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell death [GO:0010941]; translational elongation [GO:0006414] cytoplasm [GO:0005737]; cytosol [GO:0005829]; eukaryotic translation elongation factor 1 complex [GO:0005853]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "cadherin binding [GO:0045296]; DNA binding [GO:0003677]; DNA-binding transcription factor binding [GO:0140297]; guanyl-nucleotide exchange factor activity [GO:0005085]; heat shock protein binding [GO:0031072]; translation elongation factor activity [GO:0003746]; translation factor activity, RNA binding [GO:0008135]" 0 28.092 ATAPQTQHVSPMR 9.98242 0 8.91447 0 0 0 11.1789 11.3744 11.27 9.92911 9.62104 10.0764 0 11.9069 11.9328 11.1471 11.7065 10.157 9.93865 0 0 0 0 0 11.3111 11.156 12.6849 P29728 OAS2_HUMAN 2'-5'-oligoadenylate synthase 2 ((2-5')oligo(A) synthase 2) (2-5A synthase 2) (EC 2.7.7.84) (p69 OAS / p71 OAS) (p69OAS / p71OAS) OAS2 Homo sapiens (Human) defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; interleukin-27-mediated signaling pathway [GO:0070106]; negative regulation of viral genome replication [GO:0045071]; nucleobase-containing compound metabolic process [GO:0006139]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of lactation [GO:1903487]; regulation of ribonuclease activity [GO:0060700]; response to virus [GO:0009615]; RNA catabolic process [GO:0006401]; type I interferon-mediated signaling pathway [GO:0060337] cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471] 2'-5'-oligoadenylate synthetase activity [GO:0001730]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872] 0.96417 -2.4212 HKIVKEIHEQLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0625 P29762 RABP1_HUMAN Cellular retinoic acid-binding protein 1 (Cellular retinoic acid-binding protein I) (CRABP-I) CRABP1 RBP5 Homo sapiens (Human) fatty acid transport [GO:0015908]; signal transduction [GO:0007165] cytosol [GO:0005829]; nucleus [GO:0005634] fatty acid binding [GO:0005504]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841] 0.90715 -0.71223 ALGVNAMLRK 0 0 0 0 0 0 0 0 0 0 0 0 0 11.201 0 0 0 0 0 0 0 0 0 0 0 0 0 P29803 ODPAT_HUMAN "Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial (EC 1.2.4.1) (PDHE1-A type II)" PDHA2 PDHAL Homo sapiens (Human) acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099] mitochondrial matrix [GO:0005759]; mitochondrial pyruvate dehydrogenase complex [GO:0005967]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634] pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase (NAD+) activity [GO:0034604] 0.96701 -2.3219 AEGLKYYR 0 0 0 0 0 0 0 10.1694 0 0 0 0 10.5165 10.8155 0 0 12.3748 0 10.4841 10.1731 0 8.72516 0 0 8.94468 8.97272 0 P29966 MARCS_HUMAN "Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (80K-L protein) (PKCSL)" MARCKS MACS PRKCSL Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; apoptotic process [GO:0006915]; central nervous system development [GO:0007417]; mitochondrion organization [GO:0007005]; neural tube development [GO:0021915]; neurogenesis [GO:0022008]; response to endoplasmic reticulum stress [GO:0034976] actin cytoskeleton [GO:0015629]; actin filament bundle [GO:0032432]; cell cortex [GO:0005938]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; germinal vesicle [GO:0042585]; plasma membrane [GO:0005886] actin filament binding [GO:0051015]; calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; protein kinase C binding [GO:0005080] 0.70609 0.36956 AAEEPSK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.6118 0 0 0 0 0 0 0 0 0 0 0 0 0 P29973 CNGA1_HUMAN "cGMP-gated cation channel alpha-1 (Cyclic nucleotide-gated cation channel 1) (Cyclic nucleotide-gated channel alpha-1) (CNG channel alpha-1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel, photoreceptor) (Rod photoreceptor cGMP-gated channel subunit alpha)" CNGA1 CNCG CNCG1 Homo sapiens (Human) monoatomic cation transmembrane transport [GO:0098655]; response to stimulus [GO:0050896]; visual perception [GO:0007601] intracellular cyclic nucleotide activated cation channel complex [GO:0017071]; photoreceptor outer segment membrane [GO:0042622]; plasma membrane [GO:0005886] cGMP binding [GO:0030553]; intracellular cAMP-activated cation channel activity [GO:0005222]; intracellular cGMP-activated cation channel activity [GO:0005223]; protein-containing complex binding [GO:0044877] 0.9523 -1.4497 FSRMFEFFQRTETR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.6822 0 0 0 0 10.3749 0 10.6493 0 P29992 GNA11_HUMAN Guanine nucleotide-binding protein subunit alpha-11 (G alpha-11) (G-protein subunit alpha-11) (Guanine nucleotide-binding protein G(y) subunit alpha) GNA11 GA11 Homo sapiens (Human) "action potential [GO:0001508]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cellular response to pH [GO:0071467]; cranial skeletal system development [GO:1904888]; developmental pigmentation [GO:0048066]; endothelin receptor signaling pathway [GO:0086100]; entrainment of circadian clock [GO:0009649]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; heart development [GO:0007507]; ion channel modulating, G protein-coupled receptor signaling pathway [GO:0099105]; ligand-gated ion channel signaling pathway [GO:1990806]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway [GO:0007207]; phototransduction, visible light [GO:0007603]; positive regulation of insulin secretion [GO:0032024]; regulation of blood pressure [GO:0008217]; regulation of melanocyte differentiation [GO:0045634]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]" cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; heterotrimeric G-protein complex [GO:0005834]; lysosomal membrane [GO:0005765]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; synapse [GO:0045202] G protein activity [GO:0003925]; G protein-coupled receptor binding [GO:0001664]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; phospholipase activator activity [GO:0016004] 0.88479 -0.14147 ELKLLLLGTGESGK 0 0 0 0 0 0 0 0 0 0 0 0 9.23333 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P30038 AL4A1_HUMAN "Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial (P5C dehydrogenase) (EC 1.2.1.88) (Aldehyde dehydrogenase family 4 member A1) (L-glutamate gamma-semialdehyde dehydrogenase)" ALDH4A1 ALDH4 P5CDH Homo sapiens (Human) 4-hydroxyproline catabolic process [GO:0019470]; proline catabolic process [GO:0006562]; proline catabolic process to glutamate [GO:0010133]; proline metabolic process [GO:0006560] cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] 1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802] 0.21299 0.90445 SADVESVVSGTLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2417 P30040 ERP29_HUMAN Endoplasmic reticulum resident protein 29 (ERp29) (Endoplasmic reticulum resident protein 28) (ERp28) (Endoplasmic reticulum resident protein 31) (ERp31) ERP29 C12orf8 ERP28 Homo sapiens (Human) intracellular protein transport [GO:0006886]; negative regulation of gene expression [GO:0010629]; negative regulation of protein secretion [GO:0050709]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein phosphorylation [GO:0001934]; protein folding [GO:0006457]; protein secretion [GO:0009306]; protein unfolding [GO:0043335]; regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902235] cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; melanosome [GO:0042470]; membrane [GO:0016020]; smooth endoplasmic reticulum [GO:0005790]; transport vesicle [GO:0030133] protein homodimerization activity [GO:0042803]; protein-folding chaperone binding [GO:0051087] 0 9.6217 DGDFENPVPYTGAVK 9.80523 9.91388 8.46148 0 0 0 11.0935 10.7604 10.702 0 0 0 0 0 0 0 0 0 0 9.98954 0 8.58067 10.8324 10.5783 9.25765 10.2353 10.1952 P30041 PRDX6_HUMAN Peroxiredoxin-6 (EC 1.11.1.27) (1-Cys peroxiredoxin) (1-Cys PRX) (24 kDa protein) (Acidic calcium-independent phospholipase A2) (aiPLA2) (EC 3.1.1.4) (Antioxidant protein 2) (Glutathione-dependent peroxiredoxin) (Liver 2D page spot 40) (Lysophosphatidylcholine acyltransferase 5) (LPC acyltransferase 5) (LPCAT-5) (Lyso-PC acyltransferase 5) (EC 2.3.1.23) (Non-selenium glutathione peroxidase) (NSGPx) (Red blood cells page spot 12) PRDX6 AOP2 KIAA0106 Homo sapiens (Human) "cell redox homeostasis [GO:0045454]; cellular oxidant detoxification [GO:0098869]; glycerophospholipid catabolic process [GO:0046475]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; response to oxidative stress [GO:0006979]" azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] 1-acylglycerophosphocholine O-acyltransferase activity [GO:0047184]; cadherin binding [GO:0045296]; calcium-independent phospholipase A2 activity [GO:0047499]; glutathione peroxidase activity [GO:0004602]; identical protein binding [GO:0042802]; peroxiredoxin activity [GO:0051920]; phospholipase A2 activity [GO:0004623]; ubiquitin protein ligase binding [GO:0031625] 0 3.2727 DFTPVCTTELGR 0 0 0 0 0 0 0 0 0 10.209 10.4773 9.43875 0 10.8507 10.634 0 11.0595 10.9393 0 9.62983 0 0 0 0 11.4976 0 10.9449 P30044 PRDX5_HUMAN "Peroxiredoxin-5, mitochondrial (EC 1.11.1.24) (Alu corepressor 1) (Antioxidant enzyme B166) (AOEB166) (Liver tissue 2D-page spot 71B) (PLP) (Peroxiredoxin V) (Prx-V) (Peroxisomal antioxidant enzyme) (TPx type VI) (Thioredoxin peroxidase PMP20) (Thioredoxin-dependent peroxiredoxin 5)" PRDX5 ACR1 SBBI10 Homo sapiens (Human) cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979] cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777] antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxynitrite reductase activity [GO:0072541]; RNA polymerase III transcription regulatory region sequence-specific DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379] 0 7.6441 FSMVVQDGIVK 0 0 0 0 0 0 0 9.11424 0 0 0 0 0 0 0 0 0 0 0 10.0139 0 0 0 0 10.6565 11.6451 10.4688 P30048 PRDX3_HUMAN "Thioredoxin-dependent peroxide reductase, mitochondrial (EC 1.11.1.24) (Antioxidant protein 1) (AOP-1) (HBC189) (Peroxiredoxin III) (Prx-III) (Peroxiredoxin-3) (Protein MER5 homolog) (Thioredoxin-dependent peroxiredoxin 3)" PRDX3 AOP1 Homo sapiens (Human) cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of apoptotic process [GO:0043066]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]; response to oxidative stress [GO:0006979] cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] alkyl hydroperoxide reductase activity [GO:0008785]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379] 0 13.693 DYGVLLEGSGLALR 0 8.24208 0 0 0 0 8.67455 8.66003 8.50942 0 0 0 0 0 0 0 0 0 8.91028 8.9613 9.0474 9.81139 9.83911 9.64636 9.97656 9.00619 0 P30049 ATPD_HUMAN "ATP synthase subunit delta, mitochondrial (ATP synthase F1 subunit delta) (F-ATPase delta subunit)" ATP5F1D ATP5D Homo sapiens (Human) aerobic respiration [GO:0009060]; mitochondrial proton-transporting ATP synthase complex assembly [GO:0033615]; proton motive force-driven ATP synthesis [GO:0015986]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]; response to copper ion [GO:0046688] "mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial proton-transporting ATP synthase complex [GO:0005753]; mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1) [GO:0000275]; mitochondrion [GO:0005739]" "proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]" 0.55789 0.53884 AQAELVGTADEATR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0015 0 P30050 RL12_HUMAN Large ribosomal subunit protein uL11 (60S ribosomal protein L12) RPL12 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleolus [GO:0005730]; postsynaptic density [GO:0014069] large ribosomal subunit rRNA binding [GO:0070180]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0 3.5535 EILGTAQSVGCNVDGR 0 0 0 0 0 0 8.43563 9.55582 8.53247 0 0 0 0 0 0 8.78195 9.10087 9.62352 0 0 0 0 0 0 8.52705 9.46667 11.551 P30084 ECHM_HUMAN "Enoyl-CoA hydratase, mitochondrial (mECH) (mECH1) (EC 4.2.1.17) (EC 5.3.3.8) (Enoyl-CoA hydratase 1) (ECHS1) (Short-chain enoyl-CoA hydratase) (SCEH)" ECHS1 Homo sapiens (Human) branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation [GO:0006635] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] 3-hydroxypropionyl-CoA dehydratase activity [GO:0043956]; crotonyl-CoA hydratase activity [GO:0120092]; delta(3)-delta(2)-enoyl-CoA isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300] 0 3.1574 AFAAGADIK 9.65735 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.98299 9.81232 10.0492 10.3081 10.7965 10.3422 11.5222 11.3784 11.3903 P30086 PEBP1_HUMAN Phosphatidylethanolamine-binding protein 1 (PEBP-1) (HCNPpp) (Neuropolypeptide h3) (Prostatic-binding protein) (Raf kinase inhibitor protein) (RKIP) [Cleaved into: Hippocampal cholinergic neurostimulating peptide (HCNP)] PEBP1 PBP PEBP Homo sapiens (Human) negative regulation of MAPK cascade [GO:0043409]; negative regulation of peptidase activity [GO:0010466] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634] ATP binding [GO:0005524]; enzyme binding [GO:0019899]; phosphatidylethanolamine binding [GO:0008429]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; serine-type endopeptidase inhibitor activity [GO:0004867] 0 3.5918 GNDISSGTVLSDYVGSGPPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.49309 9.08489 9.02672 8.80132 8.65406 10.165 8.6908 10.6013 10.9845 9.23989 P30101 PDIA3_HUMAN Protein disulfide-isomerase A3 (EC 5.3.4.1) (58 kDa glucose-regulated protein) (58 kDa microsomal protein) (p58) (Disulfide isomerase ER-60) (Endoplasmic reticulum resident protein 57) (ER protein 57) (ERp57) (Endoplasmic reticulum resident protein 60) (ER protein 60) (ERp60) PDIA3 ERP57 ERP60 GRP58 Homo sapiens (Human) cellular response to interleukin-7 [GO:0098761]; extrinsic apoptotic signaling pathway [GO:0097191]; peptide antigen assembly with MHC class I protein complex [GO:0002502]; platelet aggregation [GO:0070527]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; protein folding [GO:0006457]; protein folding in endoplasmic reticulum [GO:0034975]; response to endoplasmic reticulum stress [GO:0034976] cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; melanosome [GO:0042470]; MHC class I peptide loading complex [GO:0042824]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; recycling endosome membrane [GO:0055038]; Tapasin-ERp57 complex [GO:0061779] cysteine-type endopeptidase activity [GO:0004197]; disulfide oxidoreductase activity [GO:0015036]; identical protein binding [GO:0042802]; phospholipase C activity [GO:0004629]; protein disulfide isomerase activity [GO:0003756]; protein-disulfide reductase activity [GO:0015035]; RNA binding [GO:0003723] 0 126.97 DGEEAGAYDGPR 12.4211 12.4177 12.0272 0 0 0 12.811 13.0634 12.742 13.0482 12.5502 11.7572 0 11.4068 8.79837 10.0139 10.8061 11.6696 13.7642 13.844 13.4459 13.3364 13.5404 13.0749 15.0155 15.3145 14.7542 P30153 2AAA_HUMAN Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (Medium tumor antigen-associated 61 kDa protein) (PP2A subunit A isoform PR65-alpha) (PP2A subunit A isoform R1-alpha) PPP2R1A Homo sapiens (Human) "apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; chromosome segregation [GO:0007059]; female meiotic nuclear division [GO:0007143]; meiotic sister chromatid cohesion, centromeric [GO:0051754]; meiotic spindle elongation [GO:0051232]; mitotic sister chromatid separation [GO:0051306]; negative regulation of cell growth [GO:0030308]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; peptidyl-serine dephosphorylation [GO:0070262]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; protein-containing complex assembly [GO:0065003]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of DNA-templated transcription [GO:0006355]; regulation of growth [GO:0040008]; regulation of meiotic cell cycle process involved in oocyte maturation [GO:1903538]; regulation of Wnt signaling pathway [GO:0030111]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]; T cell homeostasis [GO:0043029]" "chromosome, centromeric region [GO:0000775]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; lateral plasma membrane [GO:0016328]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; protein phosphatase type 2A complex [GO:0000159]" protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; protein phosphatase regulator activity [GO:0019888]; protein serine/threonine phosphatase activity [GO:0004722] 0.88422 -0.20894 RLAGGDWFTSR 0 0 0 0 0 0 0 0 0 0 10.0908 0 0 0 0 0 9.41253 0 0 0 0 0 10.4256 0 9.97785 10.3826 10.001 P30154 2AAB_HUMAN Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A subunit A isoform PR65-beta) (PP2A subunit A isoform R1-beta) PPP2R1B Homo sapiens (Human) apoptotic process involved in morphogenesis [GO:0060561]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; protein phosphatase type 2A complex [GO:0000159] protein phosphatase regulator activity [GO:0019888] 0.87183 0.02719 ELGENLPIEDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.751 0 0 0 0 0 0 P30279 CCND2_HUMAN G1/S-specific cyclin-D2 CCND2 Homo sapiens (Human) adult locomotory behavior [GO:0008344]; cell division [GO:0051301]; cellular response to X-ray [GO:0071481]; G1/S transition of mitotic cell cycle [GO:0000082]; long-term memory [GO:0007616]; mitotic cell cycle phase transition [GO:0044772]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of protein phosphorylation [GO:0001934]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079] chromatin [GO:0000785]; cyclin D2-CDK4 complex [GO:0097129]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; protein kinase binding [GO:0019901] 0.91623 -0.76616 DIQPYMRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.35423 0 0 0 0 P30281 CCND3_HUMAN G1/S-specific cyclin-D3 CCND3 Homo sapiens (Human) cell division [GO:0051301]; G1/S transition of mitotic cell cycle [GO:0000082]; mitotic cell cycle phase transition [GO:0044772]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of protein phosphorylation [GO:0001934]; regulation of cell population proliferation [GO:0042127]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of insulin receptor signaling pathway [GO:0046626]; signal transduction [GO:0007165]; T cell proliferation [GO:0042098] cyclin D3-CDK4 complex [GO:0097130]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; protein kinase binding [GO:0019901] 0.9566 -1.542 LEERYVPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1694 0 0 0 0 0 0 P30304 MPIP1_HUMAN M-phase inducer phosphatase 1 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25A) CDC25A Homo sapiens (Human) cell division [GO:0051301]; cell population proliferation [GO:0008283]; cellular response to UV [GO:0034644]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of G2/MI transition of meiotic cell cycle [GO:0110032]; protein dephosphorylation [GO:0006470]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; response to radiation [GO:0009314] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] phosphoprotein phosphatase activity [GO:0004721]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; protein-folding chaperone binding [GO:0051087] 0.92742 -1.2019 ELGPEPPHRR 8.61213 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.49673 8.94898 0 0 0 0 0 P30305 MPIP2_HUMAN M-phase inducer phosphatase 2 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25B) CDC25B CDC25HU2 Homo sapiens (Human) cell division [GO:0051301]; female meiosis I [GO:0007144]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; oocyte maturation [GO:0001556]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of G2/MI transition of meiotic cell cycle [GO:0110032]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of protein kinase activity [GO:0045860]; protein dephosphorylation [GO:0006470]; protein phosphorylation [GO:0006468] centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922] phosphoprotein phosphatase activity [GO:0004721]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725] 0.96305 -2.1507 DTPVQNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.21708 0 0 0 0 0 0 0 8.96067 0 0 0 P30405 PPIF_HUMAN "Peptidyl-prolyl cis-trans isomerase F, mitochondrial (PPIase F) (EC 5.2.1.8) (Cyclophilin D) (CyP-D) (CypD) (Cyclophilin F) (Mitochondrial cyclophilin) (CyP-M) (Rotamase F)" PPIF CYP3 Homo sapiens (Human) "apoptotic mitochondrial changes [GO:0008637]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; mitochondrial outer membrane permeabilization involved in programmed cell death [GO:1902686]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATP-dependent activity [GO:0032780]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of oxidative phosphorylation uncoupler activity [GO:2000276]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [GO:1902445]; regulation of necrotic cell death [GO:0010939]; regulation of proton-transporting ATPase activity, rotational mechanism [GO:0010849]; response to ischemia [GO:0002931]" cytoplasm [GO:0005737]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial permeability transition pore complex [GO:0005757]; mitochondrion [GO:0005739] cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755] 0.95573 -1.6418 GFGYKGSTFHR 0 0 0 0 0 9.73079 0 0 0 0 11.4262 0 0 0 0 0 0 0 9.49551 0 0 0 0 0 0 10.3067 0 P30414 NKTR_HUMAN NK-tumor recognition protein (NK-TR protein) (Natural-killer cells cyclophilin-related protein) (Peptidyl-prolyl cis-trans isomerase NKTR) (PPIase) (EC 5.2.1.8) (Rotamase) NKTR Homo sapiens (Human) protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413] cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886] cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755] 0.96978 -5.4097 DSYRSKSHSQSYSR 0 0 0 0 0 0 0 0 0 9.66759 0 9.13271 0 14.75 0 11.1648 0 0 12.1136 0 9.4822 9.60986 0 0 0 0 0 P30419 NMT1_HUMAN Glycylpeptide N-tetradecanoyltransferase 1 (EC 2.3.1.97) (Myristoyl-CoA:protein N-myristoyltransferase 1) (HsNMT1) (NMT 1) (Type I N-myristoyltransferase) (Peptide N-myristoyltransferase 1) (Protein-lysine myristoyltransferase NMT1) (EC 2.3.1.-) NMT1 NMT Homo sapiens (Human) cellular ketone metabolic process [GO:0042180]; in utero embryonic development [GO:0001701]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; N-terminal protein myristoylation [GO:0006499]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; regulation of rhodopsin mediated signaling pathway [GO:0022400] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886] glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; myristoyltransferase activity [GO:0019107]; peptidyl-lysine N6-myristoyltransferase activity [GO:0018030] 0.78349 0.26034 SYQFWDTQPVPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.22834 0 0 0 P30511 HLAF_HUMAN "HLA class I histocompatibility antigen, alpha chain F (CDA12) (HLA F antigen) (Leukocyte antigen F) (MHC class I antigen F)" HLA-F HLA-5.4 HLAF Homo sapiens (Human) "antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent [GO:0002486]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class Ib [GO:0002477]; immune response [GO:0006955]; negative regulation of natural killer cell cytokine production [GO:0002728]; negative regulation of natural killer cell degranulation [GO:0043322]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of T cell cytokine production [GO:0002725]; positive regulation of natural killer cell cytokine production [GO:0002729]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of T cell mediated cytotoxicity [GO:0001916]" cell surface [GO:0009986]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; lumenal side of endoplasmic reticulum membrane [GO:0098553]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; MHC class I protein complex [GO:0042612]; MHC class Ib protein complex [GO:0032398]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038] 14-3-3 protein binding [GO:0071889]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; signaling receptor binding [GO:0005102]; TAP1 binding [GO:0046978]; TAP2 binding [GO:0046979] 0.89787 -0.5823 YLENGKETLQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.46793 0 0 P30518 V2R_HUMAN Vasopressin V2 receptor (V2R) (AVPR V2) (Antidiuretic hormone receptor) (Renal-type arginine vasopressin receptor) AVPR2 ADHR DIR DIR3 V2R Homo sapiens (Human) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cellular response to hormone stimulus [GO:0032870]; G protein-coupled receptor signaling pathway [GO:0007186]; hemostasis [GO:0007599]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of renal sodium excretion [GO:0035814]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of systemic arterial blood pressure [GO:0003084]; positive regulation of vasoconstriction [GO:0045907]; regulation of systemic arterial blood pressure by vasopressin [GO:0001992]; renal water retention [GO:0003092]; response to cytokine [GO:0034097]; telencephalon development [GO:0021537] clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] peptide binding [GO:0042277]; vasopressin receptor activity [GO:0005000] 0.96971 -4.0225 GPDALCR 0 0 0 0 0 0 0 0 0 8.32351 0 0 0 9.32557 0 0 0 0 0 0 0 0 0 0 0 0 0 P30519 HMOX2_HUMAN Heme oxygenase 2 (HO-2) (EC 1.14.14.18) [Cleaved into: Heme oxygenase 2 soluble form] HMOX2 HO2 Homo sapiens (Human) heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979] endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579] heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872] 0.44969 0.64322 YMGDLSGGQVLKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.86888 0 P30520 PURA2_HUMAN "Adenylosuccinate synthetase isozyme 2 (AMPSase 2) (AdSS 2) (EC 6.3.4.4) (Adenylosuccinate synthetase, acidic isozyme) (Adenylosuccinate synthetase, liver isozyme) (L-type adenylosuccinate synthetase) (IMP--aspartate ligase 2)" ADSS2 ADSS Homo sapiens (Human) 'de novo' AMP biosynthetic process [GO:0044208]; AMP biosynthetic process [GO:0006167]; aspartate metabolic process [GO:0006531]; cellular response to electrical stimulus [GO:0071257]; immune system process [GO:0002376]; IMP metabolic process [GO:0046040]; response to ammonium ion [GO:0060359]; response to purine-containing compound [GO:0014074] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739] adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301] 0.78496 0.25456 CGWLDLVLLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.65397 P30531 SC6A1_HUMAN Sodium- and chloride-dependent GABA transporter 1 (GAT-1) (Solute carrier family 6 member 1) SLC6A1 GABATR GABT1 GAT1 Homo sapiens (Human) "associative learning [GO:0008306]; chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid reuptake [GO:0051936]; inorganic anion import across plasma membrane [GO:0098658]; memory [GO:0007613]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; positive regulation of gamma-aminobutyric acid secretion [GO:0014054]; response to calcium ion [GO:0051592]; response to cocaine [GO:0042220]; response to estradiol [GO:0032355]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; response to purine-containing compound [GO:0014074]; response to sucrose [GO:0009744]; response to toxic substance [GO:0009636]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]; synapse organization [GO:0050808]; transport across blood-brain barrier [GO:0150104]" axon [GO:0030424]; cell surface [GO:0009986]; GABA-ergic synapse [GO:0098982]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734] gamma-aminobutyric acid transmembrane transporter activity [GO:0015185]; gamma-aminobutyric acid:sodium:chloride symporter activity [GO:0005332]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sodium:chloride symporter activity [GO:0015378] 0.63847 0.39718 GVGWTGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1558 0 P30532 ACHA5_HUMAN Neuronal acetylcholine receptor subunit alpha-5 CHRNA5 NACHRA5 Homo sapiens (Human) behavioral response to nicotine [GO:0035095]; chemical synaptic transmission [GO:0007268]; membrane depolarization [GO:0051899]; monoatomic ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] acetylcholine-gated channel complex [GO:0005892]; dopaminergic synapse [GO:0098691]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynapse [GO:0098793]; synapse [GO:0045202] acetylcholine receptor activity [GO:0015464]; acetylcholine-gated monoatomic cation-selective channel activity [GO:0022848]; ligand-gated monoatomic ion channel activity [GO:0015276] 0.80524 0.23669 FGLAISQLVDVDEK 12.4297 0 0 9.97728 0 10.7131 12.5496 0 12.6371 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P30533 AMRP_HUMAN Alpha-2-macroglobulin receptor-associated protein (Alpha-2-MRAP) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP) LRPAP1 A2MRAP Homo sapiens (Human) amyloid-beta clearance by transcytosis [GO:0150093]; extracellular negative regulation of signal transduction [GO:1900116]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of protein binding [GO:0032091]; negative regulation of receptor internalization [GO:0002091]; negative regulation of very-low-density lipoprotein particle clearance [GO:0010916]; positive regulation of amyloid-beta clearance [GO:1900223]; regulation of receptor-mediated endocytosis [GO:0048259]; signal transduction [GO:0007165] cell surface [GO:0009986]; cis-Golgi network [GO:0005801]; endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endosome [GO:0005768]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; rough endoplasmic reticulum lumen [GO:0048237] amyloid-beta binding [GO:0001540]; heparin binding [GO:0008201]; lipase binding [GO:0035473]; low-density lipoprotein particle receptor binding [GO:0050750]; receptor antagonist activity [GO:0048019]; receptor ligand activity [GO:0048018]; signaling receptor binding [GO:0005102]; very-low-density lipoprotein particle receptor binding [GO:0070326] 0.5907 0.46271 SINQGLDR 0 0 0 0 0 0 8.86907 8.76457 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P30622 CLIP1_HUMAN CAP-Gly domain-containing linker protein 1 (Cytoplasmic linker protein 1) (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed-Sternberg intermediate filament-associated protein) (Restin) CLIP1 CYLN1 RSN Homo sapiens (Human) cytoplasmic microtubule organization [GO:0031122]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; positive regulation of microtubule polymerization [GO:0031116] cell cortex [GO:0005938]; centrosome [GO:0005813]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; intermediate filament [GO:0005882]; kinetochore [GO:0000776]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; nucleus [GO:0005634]; ruffle [GO:0001726] identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; tubulin binding [GO:0015631]; zinc ion binding [GO:0008270] 0.010076 1.8927 EEQFNMLSSDLEK 10.5553 0 11.5538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4675 0 0 0 0 0 0 0 P30740 ILEU_HUMAN Leukocyte elastase inhibitor (LEI) (Monocyte/neutrophil elastase inhibitor) (EI) (M/NEI) (Peptidase inhibitor 2) (PI-2) (Serpin B1) SERPINB1 ELANH2 MNEI PI2 Homo sapiens (Human) negative regulation of endopeptidase activity [GO:0010951]; negative regulation of interleukin-1 beta production [GO:0032691]; type B pancreatic cell proliferation [GO:0044342] collagen-containing extracellular matrix [GO:0062023]; cytolytic granule [GO:0044194]; cytoplasmic ribonucleoprotein granule [GO:0036464]; early endosome [GO:0005769]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; secretory granule lumen [GO:0034774] peptidase inhibitor activity [GO:0030414]; serine-type endopeptidase inhibitor activity [GO:0004867] 0.54529 0.57674 LGVQDLFNSSK 0 0 9.4412 0 0 0 0 0 0 0 0 0 9.25729 10.1621 9.54249 10.7163 0 12.7477 10.3188 0 8.99314 0 0 0 0 0 0 P30838 AL3A1_HUMAN "Aldehyde dehydrogenase, dimeric NADP-preferring (EC 1.2.1.5) (ALDHIII) (Aldehyde dehydrogenase 3) (Aldehyde dehydrogenase family 3 member A1)" ALDH3A1 ALDH3 Homo sapiens (Human) cellular aldehyde metabolic process [GO:0006081]; lipid metabolic process [GO:0006629]; xenobiotic metabolic process [GO:0006805] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] 3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479] 0.91786 -0.86892 AAFSSGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.0705 10.3258 9.90728 0 0 0 0 0 0 0 P30876 RPB2_HUMAN DNA-directed RNA polymerase II subunit RPB2 (EC 2.7.7.6) (DNA-directed RNA polymerase II 140 kDa polypeptide) (DNA-directed RNA polymerase II subunit B) (RNA polymerase II subunit 2) (RNA polymerase II subunit B2) POLR2B Homo sapiens (Human) transcription by RNA polymerase II [GO:0006366] "membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II, core complex [GO:0005665]" chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; metal ion binding [GO:0046872]; ribonucleoside binding [GO:0032549]; RNA binding [GO:0003723] 0.96424 -2.2708 IYAQKFIDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.68268 0 0 0 0 0 0 0 0 0 0 0 0 P30926 ACHB4_HUMAN Neuronal acetylcholine receptor subunit beta-4 CHRNB4 Homo sapiens (Human) "behavioral response to nicotine [GO:0035095]; chemical synaptic transmission [GO:0007268]; locomotory behavior [GO:0007626]; membrane depolarization [GO:0051899]; monoatomic ion transmembrane transport [GO:0034220]; monoatomic ion transport [GO:0006811]; nervous system process [GO:0050877]; neuronal action potential [GO:0019228]; positive regulation of transmission of nerve impulse [GO:0051971]; regulation of membrane potential [GO:0042391]; regulation of neurotransmitter secretion [GO:0046928]; regulation of smooth muscle contraction [GO:0006940]; signal transduction [GO:0007165]; smooth muscle contraction [GO:0006939]; synaptic transmission involved in micturition [GO:0060084]; synaptic transmission, cholinergic [GO:0007271]" acetylcholine-gated channel complex [GO:0005892]; cholinergic synapse [GO:0098981]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; specific granule membrane [GO:0035579]; synapse [GO:0045202]; tertiary granule membrane [GO:0070821] acetylcholine receptor activity [GO:0015464]; acetylcholine-gated monoatomic cation-selective channel activity [GO:0022848]; ligand-gated monoatomic ion channel activity [GO:0015276] 0.95438 -1.509 DFWLRSSGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.43313 0 0 0 0 P30939 5HT1F_HUMAN 5-hydroxytryptamine receptor 1F (5-HT-1F) (5-HT1F) (Serotonin receptor 1F) HTR1F HTR1EL Homo sapiens (Human) "adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adenylate cyclase-inhibiting serotonin receptor signaling pathway [GO:0007198]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]" dendrite [GO:0030425]; plasma membrane [GO:0005886]; synapse [GO:0045202] G protein-coupled serotonin receptor activity [GO:0004993]; neurotransmitter receptor activity [GO:0030594]; serotonin binding [GO:0051378] 0.8817 -0.30197 ELVVNVCDKCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7328 P31025 LCN1_HUMAN Lipocalin-1 (Tear lipocalin) (Tlc) (Tear prealbumin) (TP) (von Ebner gland protein) (VEG protein) LCN1 VEGP Homo sapiens (Human) proteolysis [GO:0006508]; response to stimulus [GO:0050896]; retina homeostasis [GO:0001895]; sensory perception of taste [GO:0050909] extracellular region [GO:0005576]; extracellular space [GO:0005615] chloride ion binding [GO:0031404]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; signaling receptor binding [GO:0005102]; small molecule binding [GO:0036094]; zinc ion binding [GO:0008270] 0.0080214 2.0627 NNLEALEDFEK 0 0 0 0 0 0 0 0 0 9.2375 0 9.37959 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P31040 SDHA_HUMAN "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (EC 1.3.5.1) (Flavoprotein subunit of complex II) (Fp)" SDHA SDH2 SDHF Homo sapiens (Human) "mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; nervous system development [GO:0007399]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]; respiratory electron transport chain [GO:0022904]; succinate metabolic process [GO:0006105]; tricarboxylic acid cycle [GO:0006099]" "mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]" electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; fumarate reductase (menaquinone) [GO:0102040]; succinate dehydrogenase (ubiquinone) activity [GO:0008177] 0.9655 -2.7201 DLASRDVVSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.96953 0 P31151 S10A7_HUMAN Protein S100-A7 (Psoriasin) (S100 calcium-binding protein A7) S100A7 PSOR1 S100A7C Homo sapiens (Human) angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; epidermis development [GO:0008544]; keratinocyte differentiation [GO:0030216]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of granulocyte chemotaxis [GO:0071624]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of T cell chemotaxis [GO:0010820]; response to lipopolysaccharide [GO:0032496]; response to reactive oxygen species [GO:0000302] azurophil granule lumen [GO:0035578]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; nucleus [GO:0005634] calcium ion binding [GO:0005509]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; zinc ion sequestering activity [GO:0140486] 0 12.787 DDKIEKPSLLTMMK 0 0 0 0 0 0 9.27743 8.6299 8.94588 11.8593 11.9267 8.98678 12.0714 12.4348 12.565 12.7994 12.8802 12.3961 0 0 0 0 0 0 0 0 0 P31152 MK04_HUMAN Mitogen-activated protein kinase 4 (MAP kinase 4) (MAPK 4) (EC 2.7.11.24) (Extracellular signal-regulated kinase 4) (ERK-4) (MAP kinase isoform p63) (p63-MAPK) MAPK4 ERK4 PRKM4 Homo sapiens (Human) cell cycle [GO:0007049]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; MAP kinase activity [GO:0004707]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.90768 -0.73742 VGSPSYLDKLLWR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6206 0 0 0 0 0 0 0 0 0 0 0 0 0 P31249 HXD3_HUMAN Homeobox protein Hox-D3 (Homeobox protein Hox-4A) HOXD3 HOX1D HOX4A Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; cartilage development [GO:0051216]; cell-matrix adhesion [GO:0007160]; DNA-templated transcription [GO:0006351]; embryonic skeletal system morphogenesis [GO:0048704]; glossopharyngeal nerve morphogenesis [GO:0021615]; Notch signaling pathway [GO:0007219]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; thyroid gland development [GO:0030878] aggresome [GO:0016235]; chromatin [GO:0000785]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.92546 -0.98169 GGPNASSSSATISKQIFPWMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.03083 0 0 0 0 11.3422 P31275 HXC12_HUMAN Homeobox protein Hox-C12 (Homeobox protein Hox-3F) HOXC12 HOC3F HOX3F Homo sapiens (Human) nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.91628 -0.80939 EPCAEGGGGGLKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.65091 0 0 0 0 P31276 HXC13_HUMAN Homeobox protein Hox-C13 (Homeobox protein Hox-3G) HOXC13 HOX3G Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; anterior/posterior pattern specification [GO:0009952]; hair follicle development [GO:0001942]; nail development [GO:0035878]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]; tongue morphogenesis [GO:0043587] chromatin [GO:0000785]; nucleus [GO:0005634] "chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription factor binding [GO:0140297]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]" 0.8821 -0.081946 ELEKEYAASK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0174 0 9.28397 0 0 0 12.0258 P31321 KAP1_HUMAN cAMP-dependent protein kinase type I-beta regulatory subunit PRKAR1B Homo sapiens (Human) learning or memory [GO:0007611]; negative regulation of cAMP-dependent protein kinase activity [GO:2000480]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of fear response [GO:1903367]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of sensory perception of pain [GO:1904058]; protein phosphorylation [GO:0006468]; regulation of synaptic vesicle cycle [GO:0098693] cAMP-dependent protein kinase complex [GO:0005952]; ciliary base [GO:0097546]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schaffer collateral - CA1 synapse [GO:0098685] cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; cAMP-dependent protein kinase regulator activity [GO:0008603]; molecular function inhibitor activity [GO:0140678]; protein kinase A catalytic subunit binding [GO:0034236] 0.95477 -1.5072 DYKTMTALAK 0 0 0 0 0 0 0 10.6306 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P31327 CPSM_HUMAN "Carbamoyl-phosphate synthase [ammonia], mitochondrial (EC 6.3.4.16) (Carbamoyl-phosphate synthetase I) (CPSase I)" CPS1 Homo sapiens (Human) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; carbamoyl phosphate biosynthetic process [GO:0070409]; cellular response to ammonium ion [GO:0071242]; cellular response to cAMP [GO:0071320]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to glucagon stimulus [GO:0071377]; cellular response to oleic acid [GO:0071400]; citrulline biosynthetic process [GO:0019240]; glutamine metabolic process [GO:0006541]; hepatocyte differentiation [GO:0070365]; homocysteine metabolic process [GO:0050667]; midgut development [GO:0007494]; monoatomic anion homeostasis [GO:0055081]; nitric oxide metabolic process [GO:0046209]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to dexamethasone [GO:0071548]; response to food [GO:0032094]; response to growth hormone [GO:0060416]; response to lipopolysaccharide [GO:0032496]; response to starvation [GO:0042594]; response to toxic substance [GO:0009636]; response to xenobiotic stimulus [GO:0009410]; response to zinc ion [GO:0010043]; triglyceride catabolic process [GO:0019433]; urea cycle [GO:0000050]; vasodilation [GO:0042311] cytoplasm [GO:0005737]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; carbamoyl-phosphate synthase (ammonia) activity [GO:0004087]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; endopeptidase activity [GO:0004175]; glutamate binding [GO:0016595]; metal ion binding [GO:0046872]; modified amino acid binding [GO:0072341]; phospholipid binding [GO:0005543]; potassium ion binding [GO:0030955]; protein-containing complex binding [GO:0044877]; small molecule binding [GO:0036094] 0.96907 -6.8425 DILNMEK 0 0 0 0 0 0 0 0 0 0 0 9.22323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P31350 RIR2_HUMAN Ribonucleoside-diphosphate reductase subunit M2 (EC 1.17.4.1) (Ribonucleotide reductase small chain) (Ribonucleotide reductase small subunit) RRM2 RR2 Homo sapiens (Human) 2'-deoxyribonucleotide biosynthetic process [GO:0009265]; blastocyst development [GO:0001824]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; protein heterotetramerization [GO:0051290]; ribonucleoside diphosphate metabolic process [GO:0009185] cytosol [GO:0005829]; nucleus [GO:0005634]; ribonucleoside-diphosphate reductase complex [GO:0005971] "ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]" 0.89915 -0.59186 AAAPGVEDEPLLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6145 0 0 0 0 0 11.085 0 0 0 0 P31371 FGF9_HUMAN Fibroblast growth factor 9 (FGF-9) (Glia-activating factor) (GAF) (Heparin-binding growth factor 9) (HBGF-9) FGF9 Homo sapiens (Human) activin receptor signaling pathway [GO:0032924]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle cell proliferation [GO:0060038]; cell differentiation [GO:0030154]; cell-cell signaling [GO:0007267]; chondrocyte differentiation [GO:0002062]; embryonic digestive tract development [GO:0048566]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system development [GO:0048706]; eye development [GO:0001654]; fibroblast growth factor receptor signaling pathway [GO:0008543]; inner ear morphogenesis [GO:0042472]; lung development [GO:0030324]; lung-associated mesenchyme development [GO:0060484]; male gonad development [GO:0008584]; male sex determination [GO:0030238]; mesenchymal cell proliferation [GO:0010463]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching [GO:1905931]; negative regulation of Wnt signaling pathway [GO:0030178]; osteoblast differentiation [GO:0001649]; positive regulation of activin receptor signaling pathway [GO:0032927]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of gene expression [GO:0010628]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reproductive process [GO:2000243]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein import into nucleus [GO:0006606]; regulation of cell migration [GO:0030334]; regulation of timing of cell differentiation [GO:0048505]; Sertoli cell proliferation [GO:0060011]; signal transduction [GO:0007165]; smoothened signaling pathway [GO:0007224]; stem cell proliferation [GO:0072089]; substantia nigra development [GO:0021762]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615] fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201] 0.87159 0.064881 GVDSGLYLGMNEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.34509 0 0 0 0 0 0 P31629 ZEP2_HUMAN Transcription factor HIVEP2 (Human immunodeficiency virus type I enhancer-binding protein 2) (HIV-EP2) (MHC-binding protein 2) (MBP-2) HIVEP2 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.964 -2.4049 APLPGQK 0 0 0 0 0 0 0 0 9.59738 9.2572 0 0 0 8.41007 12.4062 0 12.8456 8.54871 9.19101 0 0 0 0 0 0 0 0 P31641 SC6A6_HUMAN Sodium- and chloride-dependent taurine transporter (Solute carrier family 6 member 6) SLC6A6 Homo sapiens (Human) alanine transport [GO:0032328]; amino acid import across plasma membrane [GO:0089718]; amino acid transport [GO:0006865]; gamma-aminobutyric acid import [GO:0051939]; import across plasma membrane [GO:0098739]; modulation of chemical synaptic transmission [GO:0050804]; neurotransmitter transport [GO:0006836]; nitrogen compound transport [GO:0071705]; positive regulation of cell differentiation [GO:0045597]; positive regulation of necrotic cell death [GO:0010940]; sodium ion transmembrane transport [GO:0035725]; taurine transport [GO:0015734]; transport across blood-brain barrier [GO:0150104] apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; dendrite [GO:0030425]; GABA-ergic synapse [GO:0098982]; membrane [GO:0016020]; microvillus membrane [GO:0031528]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; plasma membrane protein complex [GO:0098797]; postsynaptic membrane [GO:0045211] alanine transmembrane transporter activity [GO:0022858]; amino acid transmembrane transporter activity [GO:0015171]; amino acid:sodium symporter activity [GO:0005283]; gamma-aminobutyric acid transmembrane transporter activity [GO:0015185]; gamma-aminobutyric acid:sodium:chloride symporter activity [GO:0005332]; taurine transmembrane transporter activity [GO:0005368]; taurine:sodium symporter activity [GO:0005369] 0.92166 -1.1233 GVRSTGK 10.6492 10.6078 10.6249 0 0 0 10.9748 11.1347 11.1295 9.47717 9.88693 10.2634 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P31644 GBRA5_HUMAN Gamma-aminobutyric acid receptor subunit alpha-5 (GABA(A) receptor subunit alpha-5) GABRA5 Homo sapiens (Human) "associative learning [GO:0008306]; behavioral fear response [GO:0001662]; brain development [GO:0007420]; chloride transmembrane transport [GO:1902476]; cochlea development [GO:0090102]; gamma-aminobutyric acid signaling pathway [GO:0007214]; inner ear receptor cell development [GO:0060119]; innervation [GO:0060384]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system process [GO:0050877]; regulation of postsynaptic membrane potential [GO:0060078]; sensory perception of sound [GO:0007605]; signal transduction [GO:0007165]; synaptic transmission, GABAergic [GO:0051932]" chloride channel complex [GO:0034707]; cytosol [GO:0005829]; dendrite membrane [GO:0032590]; GABA-A receptor complex [GO:1902711]; GABA-ergic synapse [GO:0098982]; neuronal cell body membrane [GO:0032809]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic specialization membrane [GO:0099634]; presynaptic membrane [GO:0042734]; synapse [GO:0045202] GABA receptor binding [GO:0050811]; GABA-A receptor activity [GO:0004890]; GABA-gated chloride ion channel activity [GO:0022851]; inhibitory extracellular ligand-gated monoatomic ion channel activity [GO:0005237]; ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; signaling receptor activity [GO:0038023]; transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315] 0.89881 -0.57387 QSWKDERLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.64021 0 0 0 0 0 P31645 SC6A4_HUMAN Sodium-dependent serotonin transporter (SERT) (5HT transporter) (5HTT) (Solute carrier family 6 member 4) SLC6A4 HTT SERT Homo sapiens (Human) "brain morphogenesis [GO:0048854]; cellular response to cGMP [GO:0071321]; cellular response to retinoic acid [GO:0071300]; circadian rhythm [GO:0007623]; memory [GO:0007613]; monoamine transport [GO:0015844]; negative regulation of cerebellar granule cell precursor proliferation [GO:0021941]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of organ growth [GO:0046621]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; neurotransmitter transport [GO:0006836]; positive regulation of cell cycle [GO:0045787]; positive regulation of gene expression [GO:0010628]; positive regulation of serotonin secretion [GO:0014064]; regulation of thalamus size [GO:0090067]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to toxic substance [GO:0009636]; response to xenobiotic stimulus [GO:0009410]; serotonin uptake [GO:0051610]; social behavior [GO:0035176]; sodium ion transmembrane transport [GO:0035725]; sperm ejaculation [GO:0042713]; vasoconstriction [GO:0042310]" endomembrane system [GO:0012505]; endosome membrane [GO:0010008]; focal adhesion [GO:0005925]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; serotonergic synapse [GO:0099154]; synapse [GO:0045202] actin filament binding [GO:0051015]; cocaine binding [GO:0019811]; identical protein binding [GO:0042802]; monoamine transmembrane transporter activity [GO:0008504]; neurotransmitter transmembrane transporter activity [GO:0005326]; nitric-oxide synthase binding [GO:0050998]; serotonin binding [GO:0051378]; serotonin:sodium:chloride symporter activity [GO:0005335]; sodium ion binding [GO:0031402]; syntaxin-1 binding [GO:0017075] 0.91553 -0.77028 NGCISIWRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.02874 0 0 0 0 P31689 DNJA1_HUMAN DnaJ homolog subfamily A member 1 (DnaJ protein homolog 2) (HSDJ) (Heat shock 40 kDa protein 4) (Heat shock protein J2) (HSJ-2) (Human DnaJ protein 2) (hDj-2) DNAJA1 DNAJ2 HDJ2 HSJ2 HSPF4 Homo sapiens (Human) androgen receptor signaling pathway [GO:0030521]; flagellated sperm motility [GO:0030317]; negative regulation of apoptotic process [GO:0043066]; negative regulation of establishment of protein localization to mitochondrion [GO:1903748]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of apoptotic process [GO:0043065]; protein folding [GO:0006457]; protein localization to mitochondrion [GO:0070585]; protein refolding [GO:0042026]; regulation of protein transport [GO:0051223]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; spermatogenesis [GO:0007283]; toxin transport [GO:1901998] cytoplasm [GO:0005737]; cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] ATP binding [GO:0005524]; ATPase activator activity [GO:0001671]; C3HC4-type RING finger domain binding [GO:0055131]; G protein-coupled receptor binding [GO:0001664]; Hsp70 protein binding [GO:0030544]; low-density lipoprotein particle receptor binding [GO:0050750]; metal ion binding [GO:0046872]; protein-folding chaperone binding [GO:0051087]; Tat protein binding [GO:0030957]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082] 0.0077922 2.0428 ISPKDRCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6213 0 P31749 AKT1_HUMAN RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha) AKT1 PKB RAC Homo sapiens (Human) activation-induced cell death of T cells [GO:0006924]; anoikis [GO:0043276]; apoptotic mitochondrial changes [GO:0008637]; behavioral response to pain [GO:0048266]; carbohydrate transport [GO:0008643]; cell differentiation [GO:0030154]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell population proliferation [GO:0008283]; cellular response to cadmium ion [GO:0071276]; cellular response to decreased oxygen levels [GO:0036294]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to insulin stimulus [GO:0032869]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to oxidised low-density lipoprotein particle stimulus [GO:0140052]; cellular response to prostaglandin E stimulus [GO:0071380]; cellular response to reactive oxygen species [GO:0034614]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cytokine-mediated signaling pathway [GO:0019221]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization to mitochondrion [GO:0072655]; excitatory postsynaptic potential [GO:0060079]; execution phase of apoptosis [GO:0097194]; fibroblast migration [GO:0010761]; G protein-coupled receptor signaling pathway [GO:0007186]; gene expression [GO:0010467]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; glycogen cell differentiation involved in embryonic placenta development [GO:0060709]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; interleukin-18-mediated signaling pathway [GO:0035655]; intracellular signal transduction [GO:0035556]; labyrinthine layer blood vessel development [GO:0060716]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; maintenance of protein location in mitochondrion [GO:0072656]; mammalian oogenesis stage [GO:0022605]; mammary gland epithelial cell differentiation [GO:0060644]; maternal placenta development [GO:0001893]; mitigation of host antiviral defense response [GO:0019049]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fatty acid beta-oxidation [GO:0031999]; negative regulation of gene expression [GO:0010629]; negative regulation of innate immune response [GO:0045824]; negative regulation of leukocyte cell-cell adhesion [GO:1903038]; negative regulation of long-chain fatty acid import across plasma membrane [GO:0010748]; negative regulation of lymphocyte migration [GO:2000402]; negative regulation of macroautophagy [GO:0016242]; negative regulation of neuron death [GO:1901215]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein binding [GO:0032091]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of proteolysis [GO:0045861]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; NIK/NF-kappaB signaling [GO:0038061]; nitric oxide biosynthetic process [GO:0006809]; osteoblast differentiation [GO:0001649]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peripheral nervous system myelin maintenance [GO:0032287]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphorylation [GO:0016310]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endodeoxyribonuclease activity [GO:0032079]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose import [GO:0046326]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of organ growth [GO:0046622]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to endoplasmic reticulum [GO:1905552]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of sodium ion transport [GO:0010765]; positive regulation of TORC1 signaling [GO:1904263]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autophosphorylation [GO:0046777]; protein import into nucleus [GO:0006606]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of cell migration [GO:0030334]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of mRNA stability [GO:0043488]; regulation of myelination [GO:0031641]; regulation of neuron projection development [GO:0010975]; regulation of postsynapse organization [GO:0099175]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of translation [GO:0006417]; regulation of tRNA methylation [GO:0110002]; regulation of type B pancreatic cell development [GO:2000074]; response to fluid shear stress [GO:0034405]; response to food [GO:0032094]; response to growth factor [GO:0070848]; response to growth hormone [GO:0060416]; response to heat [GO:0009408]; response to insulin-like growth factor stimulus [GO:1990418]; response to oxidative stress [GO:0006979]; response to UV-A [GO:0070141]; signal transduction [GO:0007165]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; striated muscle cell differentiation [GO:0051146]; T cell costimulation [GO:0031295]; TOR signaling [GO:0031929] cell cortex [GO:0005938]; cell-cell junction [GO:0005911]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; lamellipodium [GO:0030027]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]; spindle [GO:0005819]; vesicle [GO:0031982] "14-3-3 protein binding [GO:0071889]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; nitric-oxide synthase regulator activity [GO:0030235]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; potassium channel activator activity [GO:0099104]; protein homodimerization activity [GO:0042803]; protein kinase activator activity [GO:0030295]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine kinase inhibitor activity [GO:0030291]; protein serine/threonine/tyrosine kinase activity [GO:0004712]" 0.96841 -3.9186 EEWTTAIQTVADGLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.16777 0 0 0 0 0 0 0 P31930 QCR1_HUMAN "Cytochrome b-c1 complex subunit 1, mitochondrial (Complex III subunit 1) (Core protein I) (Ubiquinol-cytochrome-c reductase complex core protein 1)" UQCRC1 Homo sapiens (Human) "aerobic respiration [GO:0009060]; cellular respiration [GO:0045333]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; oxidative phosphorylation [GO:0006119]; response to activity [GO:0014823]; response to alkaloid [GO:0043279]" mitochondrial inner membrane [GO:0005743]; mitochondrial respirasome [GO:0005746]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739] metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; ubiquinol-cytochrome-c reductase activity [GO:0008121]; ubiquitin protein ligase binding [GO:0031625] 0.35828 0.75134 FTGSEIR 9.45432 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.25113 10.2303 0 P31939 PUR9_HUMAN "Bifunctional purine biosynthesis protein ATIC (AICAR transformylase/inosine monophosphate cyclohydrolase) (ATIC) [Cleaved into: Bifunctional purine biosynthesis protein ATIC, N-terminally processed] [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase) (AICAR formyltransferase) (AICAR transformylase); Inosine 5'-monophosphate cyclohydrolase (IMP cyclohydrolase) (EC 3.5.4.10) (IMP synthase) (Inosinicase)]" ATIC PURH OK/SW-cl.86 Homo sapiens (Human) 'de novo' AMP biosynthetic process [GO:0044208]; 'de novo' IMP biosynthetic process [GO:0006189]; 'de novo' XMP biosynthetic process [GO:0097294]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; GMP biosynthetic process [GO:0006177]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886] cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803] 0.29037 0.82271 DAGLAVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.06205 0 0 0 0 0 0 0 0 0 P31942 HNRH3_HUMAN Heterogeneous nuclear ribonucleoprotein H3 (hnRNP H3) (Heterogeneous nuclear ribonucleoprotein 2H9) (hnRNP 2H9) HNRNPH3 HNRPH3 Homo sapiens (Human) "epithelial cell differentiation [GO:0030855]; mRNA splicing, via spliceosome [GO:0000398]; regulation of RNA splicing [GO:0043484]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]" nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681] RNA binding [GO:0003723] 0 8.0106 ATENDIANFFSPLNPIR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.12567 0 9.60027 0 0 0 0 0 0 0 0 0 10.2544 9.9587 P31943 HNRH1_HUMAN "Heterogeneous nuclear ribonucleoprotein H (hnRNP H) [Cleaved into: Heterogeneous nuclear ribonucleoprotein H, N-terminally processed]" HNRNPH1 HNRPH HNRPH1 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; regulation of RNA splicing [GO:0043484]; RNA processing [GO:0006396]" catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] identical protein binding [GO:0042802]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723] 0 26.157 ATENDIYNFFSPLNPVR 0 0 0 0 0 0 8.88999 0 8.8895 0 0 0 0 0 0 0 0 0 9.94446 10.2826 10.0651 11.2586 11.2754 10.6878 0 0 11.4623 P31946 1433B_HUMAN "14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]" YWHAB Homo sapiens (Human) cytoplasmic sequestering of protein [GO:0051220]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of protein dephosphorylation [GO:0035308]; positive regulation of catalytic activity [GO:0043085]; protein targeting [GO:0006605]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; melanosome [GO:0042470]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; vacuolar membrane [GO:0005774] cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; protein domain specific binding [GO:0019904]; protein kinase inhibitor activity [GO:0004860] 0.42781 0.6626 DSTLIMQLLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.76598 0 11.0137 0 9.7294 P31947 1433S_HUMAN 14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin) SFN HME1 Homo sapiens (Human) establishment of skin barrier [GO:0061436]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinization [GO:0031424]; keratinocyte development [GO:0003334]; keratinocyte proliferation [GO:0043616]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell growth [GO:0030307]; positive regulation of epidermal cell differentiation [GO:0045606]; positive regulation of protein export from nucleus [GO:0046827]; protein export from nucleus [GO:0006611]; protein kinase A signaling [GO:0010737]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of epidermal cell division [GO:0010482]; release of cytochrome c from mitochondria [GO:0001836]; signal transduction [GO:0007165]; stem cell proliferation [GO:0072089] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634] cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; protein kinase C inhibitor activity [GO:0008426] 0.0097087 1.7876 DSTLIMQLLR 0 0 0 8.95076 9.85215 0 10.8923 10.999 11.1105 0 0 11.2965 0 0 0 10.3844 0 9.97427 0 0 0 0 0 0 10.8865 10.9891 0 P31948 STIP1_HUMAN Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Renal carcinoma antigen NY-REN-11) (Transformation-sensitive protein IEF SSP 3521) STIP1 Homo sapiens (Human) cellular response to interleukin-7 [GO:0098761] cytosol [GO:0005829]; dynein axonemal particle [GO:0120293]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; protein folding chaperone complex [GO:0101031]; protein-containing complex [GO:0032991] Hsp90 protein binding [GO:0051879]; RNA binding [GO:0003723] 0 5.1583 IGNSYFKEEK 0 8.61405 0 0 0 0 8.73738 8.75372 0 9.08553 8.86959 10.0562 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P31949 S10AB_HUMAN "Protein S100-A11 (Calgizzarin) (Metastatic lymph node gene 70 protein) (MLN 70) (Protein S100-C) (S100 calcium-binding protein A11) [Cleaved into: Protein S100-A11, N-terminally processed]" S100A11 MLN70 S100C Homo sapiens (Human) negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; positive regulation of smooth muscle cell migration [GO:0014911]; signal transduction [GO:0007165] adherens junction [GO:0005912]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774] cadherin binding involved in cell-cell adhesion [GO:0098641]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548] 0 5.4962 DGYNYTLSK 0 0 0 0 0 0 8.99135 9.02034 0 11.818 10.9177 10.9123 9.19572 0 0 0 0 0 0 0 0 9.56318 0 0 9.40538 9.19103 9.08473 P31995 FCG2C_HUMAN Low affinity immunoglobulin gamma Fc region receptor II-c (IgG Fc receptor II-c) (CDw32) (Fc-gamma RII-c) (Fc-gamma-RIIc) (FcRII-c) (CD antigen CD32) FCGR2C CD32 FCG2 IGFR2 Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; immune response [GO:0006955] cytoplasm [GO:0005737]; membrane [GO:0016020]; plasma membrane [GO:0005886] IgG binding [GO:0019864]; transmembrane signaling receptor activity [GO:0004888] 0.93345 -1.2832 ISANSTDPVK 0 0 0 0 0 0 0 0 0 0 9.90417 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.85225 0 P32004 L1CAM_HUMAN Neural cell adhesion molecule L1 (N-CAM-L1) (NCAM-L1) (CD antigen CD171) L1CAM CAML1 MIC5 Homo sapiens (Human) axon development [GO:0061564]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; chemotaxis [GO:0006935]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399]; neuron projection development [GO:0031175]; positive regulation of axon extension [GO:0045773]; synapse organization [GO:0050808] axon [GO:0030424]; axonal growth cone [GO:0044295]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; dendrite [GO:0030425]; focal adhesion [GO:0005925]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886] axon guidance receptor activity [GO:0008046]; protein domain specific binding [GO:0019904] 0.96232 -2.081 EGQCNFRFHILFK 0 0 0 10.3612 0 10.6348 0 0 0 10.9334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P32019 I5P2_HUMAN "Type II inositol 1,4,5-trisphosphate 5-phosphatase (EC 3.1.3.36) (75 kDa inositol polyphosphate-5-phosphatase) (Phosphoinositide 5-phosphatase) (5PTase)" INPP5B OCRL2 Homo sapiens (Human) flagellated sperm motility [GO:0030317]; in utero embryonic development [GO:0001701]; inositol phosphate metabolic process [GO:0043647]; phosphatidylinositol dephosphorylation [GO:0046856]; regulation of protein processing [GO:0070613]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283] cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886] "inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity [GO:0052659]; inositol-1,4,5-trisphosphate 5-phosphatase activity [GO:0052658]; metal ion binding [GO:0046872]; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity [GO:0004439]" 0.88889 -0.43921 AVSEGLHPDAKYAK 0 0 0 0 11.5853 0 0 0 0 9.7655 9.7473 9.53966 0 0 11.0577 0 0 0 0 0 0 0 0 0 0 0 10.6379 P32119 PRDX2_HUMAN Peroxiredoxin-2 (EC 1.11.1.24) (Natural killer cell-enhancing factor B) (NKEF-B) (PRP) (Thiol-specific antioxidant protein) (TSA) (Thioredoxin peroxidase 1) (Thioredoxin-dependent peroxide reductase 1) (Thioredoxin-dependent peroxiredoxin 2) PRDX2 NKEFB TDPX1 Homo sapiens (Human) cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; defense response to tumor cell [GO:0002357]; extrinsic apoptotic signaling pathway [GO:0097191]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell differentiation [GO:0045581]; positive regulation of blood coagulation [GO:0030194]; positive regulation of MAPK cascade [GO:0043410]; regulation of apoptotic process [GO:0042981]; regulation of hydrogen peroxide metabolic process [GO:0010310]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in inflammatory response [GO:0002536]; response to lipopolysaccharide [GO:0032496]; response to oxidative stress [GO:0006979]; T cell homeostasis [GO:0043029]; T cell proliferation [GO:0042098]; thymus development [GO:0048538] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062] antioxidant activity [GO:0016209]; thioredoxin peroxidase activity [GO:0008379] 0 39.85 ATAVVDGAFK 0 8.92273 8.76052 0 0 0 0 9.62441 10.7819 10.5074 0 10.0783 0 0 0 10.8491 10.3293 0 0 0 10.2662 9.09837 10.7171 10.2739 11.8971 11.5262 9.64227 P32239 GASR_HUMAN Gastrin/cholecystokinin type B receptor (CCK-B receptor) (CCK-BR) (Cholecystokinin-2 receptor) (CCK2-R) CCKBR CCKRB Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; cholecystokinin signaling pathway [GO:0038188]; digestive tract development [GO:0048565]; gastric acid secretion [GO:0001696]; gland development [GO:0048732]; pH reduction [GO:0045851]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204] intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886] 1-phosphatidylinositol-3-kinase regulator activity [GO:0046935]; cholecystokinin receptor activity [GO:0004951]; gastrin receptor activity [GO:0015054]; peptide hormone binding [GO:0017046]; type B gastrin/cholecystokinin receptor binding [GO:0031741] 0.95174 -1.4248 QACLETCARCCPRPPRARPR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2041 0 0 0 0 0 0 0 0 8.53966 0 0 0 0 P32242 OTX1_HUMAN Homeobox protein OTX1 (Orthodenticle homolog 1) OTX1 Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; diencephalon morphogenesis [GO:0048852]; inner ear morphogenesis [GO:0042472]; metencephalon development [GO:0022037]; midbrain development [GO:0030901]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.80923 0.22682 LNFNSPDCLDYK 0 0 0 10.2635 0 0 0 0 0 0 0 0 8.89482 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P32248 CCR7_HUMAN C-C chemokine receptor type 7 (C-C CKR-7) (CC-CKR-7) (CCR-7) (BLR2) (CDw197) (Epstein-Barr virus-induced G-protein coupled receptor 1) (EBI1) (EBV-induced G-protein coupled receptor 1) (MIP-3 beta receptor) (CD antigen CD197) CCR7 CMKBR7 EBI1 EVI1 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; cellular response to cytokine stimulus [GO:0071345]; dendritic cell chemotaxis [GO:0002407]; establishment of T cell polarity [GO:0001768]; G protein-coupled receptor signaling pathway [GO:0007186]; homeostasis of number of cells [GO:0048872]; immune response [GO:0006955]; inflammatory response [GO:0006954]; lymphocyte migration into lymph node [GO:0097022]; mature conventional dendritic cell differentiation [GO:0097029]; myeloid dendritic cell chemotaxis [GO:0002408]; negative regulation of dendritic cell apoptotic process [GO:2000669]; negative regulation of interleukin-12 production [GO:0032695]; negative thymic T cell selection [GO:0045060]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell motility [GO:2000147]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation [GO:2000526]; positive regulation of humoral immune response [GO:0002922]; positive regulation of hypersensitivity [GO:0002885]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of immunological synapse formation [GO:2000522]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of JNK cascade [GO:0046330]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of T cell costimulation [GO:2000525]; positive regulation of T cell receptor signaling pathway [GO:0050862]; regulation of dendritic cell dendrite assembly [GO:2000547]; regulation of interleukin-1 beta production [GO:0032651]; regulation of type II interferon production [GO:0032649]; release of sequestered calcium ion into cytosol [GO:0051209]; response to lipopolysaccharide [GO:0032496]; response to nitric oxide [GO:0071731]; response to prostaglandin E [GO:0034695]; ruffle organization [GO:0031529] cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886] C-C chemokine receptor activity [GO:0016493]; C-C motif chemokine 19 receptor activity [GO:0038117]; C-C motif chemokine 21 receptor activity [GO:0038121]; chemokine (C-C motif) ligand 19 binding [GO:0035757]; chemokine (C-C motif) ligand 21 binding [GO:0035758]; G protein-coupled receptor activity [GO:0004930] 0.95158 -1.429 DLGCLSQEQLRQWSSCRHIR 0 0 0 0 13.3366 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P32298 GRK4_HUMAN G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4) (ITI1) GRK4 GPRK2L GPRK4 Homo sapiens (Human) protein phosphorylation [GO:0006468]; receptor internalization [GO:0031623]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of signal transduction [GO:0009966]; signal transduction [GO:0007165] cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; photoreceptor disc membrane [GO:0097381]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; rhodopsin kinase activity [GO:0050254] 0.88945 -0.44568 AFEECTRVAHNYLR 9.2133 8.89318 0 0 0 0 0 0 0 9.46471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P32314 FOXN2_HUMAN Forkhead box protein N2 (Human T-cell leukemia virus enhancer factor) FOXN2 HTLF Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; skeletal muscle cell differentiation [GO:0035914] chromatin [GO:0000785]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "cis-regulatory region sequence-specific DNA binding [GO:0000987]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.95111 -1.4194 ISEKGQSGK 0 0 0 0 0 0 0 0 0 9.26845 0 0 0 0 0 0 0 0 0 0 8.77926 0 0 0 0 0 0 P32320 CDD_HUMAN Cytidine deaminase (EC 3.5.4.5) (Cytidine aminohydrolase) CDA CDD Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; cellular response to external biotic stimulus [GO:0071217]; cytidine deamination [GO:0009972]; cytosine metabolic process [GO:0019858]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; pyrimidine-containing compound salvage [GO:0008655]; response to cycloheximide [GO:0046898]; UMP salvage [GO:0044206] cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724] cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; nucleoside binding [GO:0001882]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270] 0.65262 0.39575 AVSEGYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.19786 0 P32418 NAC1_HUMAN Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1) SLC8A1 CNC NCX1 Homo sapiens (Human) calcium ion export [GO:1901660]; calcium ion homeostasis [GO:0055074]; calcium ion import [GO:0070509]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport into cytosol [GO:0060402]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cell communication by electrical coupling involved in cardiac conduction [GO:0086064]; cellular response to caffeine [GO:0071313]; cellular response to cAMP [GO:0071320]; cellular response to hypoxia [GO:0071456]; cellular response to reactive oxygen species [GO:0034614]; intracellular calcium ion homeostasis [GO:0006874]; intracellular sodium ion homeostasis [GO:0006883]; membrane depolarization during cardiac muscle cell action potential [GO:0086012]; monoatomic ion transport [GO:0006811]; muscle contraction [GO:0006936]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; positive regulation of bone mineralization [GO:0030501]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of the force of heart contraction [GO:0098735]; regulation of cardiac conduction [GO:1903779]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling [GO:0010649]; regulation of gene expression [GO:0010468]; regulation of heart rate [GO:0002027]; regulation of sodium ion transport [GO:0002028]; regulation of the force of heart contraction [GO:0002026]; relaxation of cardiac muscle [GO:0055119]; relaxation of smooth muscle [GO:0044557]; response to ATP [GO:0033198]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to immobilization stress [GO:0035902]; response to muscle stretch [GO:0035994]; response to nutrient [GO:0007584]; response to xenobiotic stimulus [GO:0009410]; sodium ion export across plasma membrane [GO:0036376]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]; telencephalon development [GO:0021537]; vascular associated smooth muscle contraction [GO:0014829] axon [GO:0030424]; axon terminus [GO:0043679]; cell periphery [GO:0071944]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; intercalated disc [GO:0014704]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; sarcolemma [GO:0042383]; synapse [GO:0045202]; T-tubule [GO:0030315]; Z disc [GO:0030018] ankyrin binding [GO:0030506]; calcium ion binding [GO:0005509]; calcium:monoatomic cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration [GO:1905060]; calcium:sodium antiporter activity [GO:0005432]; calmodulin binding [GO:0005516]; cytoskeletal protein binding [GO:0008092]; monoatomic ion antiporter activity involved in regulation of postsynaptic membrane potential [GO:0099580]; transmembrane transporter binding [GO:0044325] 0.84273 0.17628 DQDDEEARREMAR 9.76671 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.12596 0 0 0 0 0 0 0 P32456 GBP2_HUMAN Guanylate-binding protein 2 (EC 3.6.5.-) (GTP-binding protein 2) (GBP-2) (HuGBP-2) (Guanine nucleotide-binding protein 2) (Interferon-induced guanylate-binding protein 2) GBP2 Homo sapiens (Human) activation of innate immune response [GO:0002218]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to type II interferon [GO:0071346]; cytolysis in another organism [GO:0051715]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; immune response [GO:0006955]; positive regulation of AIM2 inflammasome complex assembly [GO:0140973]; positive regulation of pyroptosis [GO:0140639]; protein localization to nucleus [GO:0034504] cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; molecular function inhibitor activity [GO:0140678]; protein homodimerization activity [GO:0042803] 0.91423 -0.78787 KSKSFNDPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0476 0 0 P32754 HPPD_HUMAN 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4-hydroxyphenylpyruvic acid oxidase) (4HPPD) (HPD) (HPPDase) HPD PPD Homo sapiens (Human) L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572] cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139] 4-hydroxyphenylpyruvate dioxygenase activity [GO:0003868]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803] 0.88204 -0.018755 GAKIMREPWVEQDK 0 9.90442 9.93264 0 0 0 0 0 0 9.56213 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P32856 STX2_HUMAN Syntaxin-2 (Epimorphin) STX2 EPIM STX2A STX2B STX2C Homo sapiens (Human) acrosome reaction [GO:0007340]; animal organ morphogenesis [GO:0009887]; cellular response to oxidative stress [GO:0034599]; cornified envelope assembly [GO:1903575]; ectoderm development [GO:0007398]; exocytosis [GO:0006887]; intracellular protein transport [GO:0006886]; signal transduction [GO:0007165]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; vesicle docking [GO:0048278] basolateral plasma membrane [GO:0016323]; endomembrane system [GO:0012505]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886]; presynaptic active zone membrane [GO:0048787]; protein-containing complex [GO:0032991]; SNARE complex [GO:0031201]; synaptic vesicle [GO:0008021] calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; SNAP receptor activity [GO:0005484]; SNARE binding [GO:0000149]; structural molecule activity [GO:0005198] 0.35714 0.75427 KNDDGDTVVVVEK 0 0 0 0 0 0 0 8.52093 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P32881 IFNA8_HUMAN Interferon alpha-8 (IFN-alpha-8) (Interferon alpha-B) (LeIF B) (Interferon alpha-B2) IFNA8 Homo sapiens (Human) adaptive immune response [GO:0002250]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; cellular response to virus [GO:0098586]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; natural killer cell activation involved in immune response [GO:0002323]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon-mediated signaling pathway [GO:0060337] extracellular region [GO:0005576]; extracellular space [GO:0005615] cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; type I interferon receptor binding [GO:0005132] 0.87955 0.012542 ISPFSCLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.63218 0 0 0 0 0 P32926 DSG3_HUMAN Desmoglein-3 (130 kDa pemphigus vulgaris antigen) (PVA) (Cadherin family member 6) DSG3 CDHF6 Homo sapiens (Human) cell-cell adhesion [GO:0098609]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] cornified envelope [GO:0001533]; cytosol [GO:0005829]; desmosome [GO:0030057]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.91673 -0.76771 ITSDYQATQK 9.16199 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3529 0 0 0 P32942 ICAM3_HUMAN Intercellular adhesion molecule 3 (ICAM-3) (CDw50) (ICAM-R) (CD antigen CD50) ICAM3 Homo sapiens (Human) cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; phagocytosis [GO:0006909] extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] integrin binding [GO:0005178]; signaling receptor binding [GO:0005102] 0.8081 0.2273 ADQEGAR 11.3836 11.4005 11.1716 0 8.53134 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P32969 RL9_HUMAN Large ribosomal subunit protein uL6 (60S ribosomal protein L9) RPL9 OK/SW-cl.103; RPL9P7; RPL9P8; RPL9P9 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribosome [GO:0005840] RNA binding [GO:0003723]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735] 0.10595 1.1489 FLDGIYVSEK 0 0 0 0 0 0 8.73796 8.89573 8.49905 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P32970 CD70_HUMAN CD70 antigen (CD27 ligand) (CD27-L) (Tumor necrosis factor ligand superfamily member 7) (CD antigen CD70) CD70 CD27L CD27LG TNFSF7 Homo sapiens (Human) B cell mediated immunity [GO:0019724]; B cell proliferation [GO:0042100]; cell-cell signaling [GO:0007267]; extrinsic apoptotic signaling pathway [GO:0097191]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell mediated immunity [GO:0002456]; tumor necrosis factor-mediated signaling pathway [GO:0033209] extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] cytokine activity [GO:0005125]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164] 0.76532 0.27982 LYWQGGPALGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.67571 0 0 0 0 0 0 0 0 0 P33032 MC5R_HUMAN Melanocortin receptor 5 (MC5-R) (MC-2) MC5R Homo sapiens (Human) "adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]" plasma membrane [GO:0005886] hormone binding [GO:0042562]; melanocortin receptor activity [GO:0004977] 0.9558 -1.5508 TFKEIICCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1267 0 0 0 0 0 0 0 0 0 P33076 C2TA_HUMAN MHC class II transactivator (CIITA) (EC 2.3.1.-) (EC 2.7.11.1) CIITA MHC2TA Homo sapiens (Human) immune response [GO:0006955]; inflammatory response [GO:0006954]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral entry into host cell [GO:0046597]; phosphorylation [GO:0016310]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to antibiotic [GO:0046677]; response to type II interferon [GO:0034341] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; PML body [GO:0016605] acyltransferase activity [GO:0016746]; ATP binding [GO:0005524]; DNA-binding transcription factor binding [GO:0140297]; GTP binding [GO:0005525]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein-containing complex binding [GO:0044877]; transcription cis-regulatory region binding [GO:0000976]; transcription coactivator activity [GO:0003713] 0.96117 -2.563 FTIEPFKAKSLK 0 0 0 8.95076 0 0 0 0 0 0 0 0 0 10.1896 9.39288 0 0 10.2959 0 0 0 0 0 0 0 0 0 P33121 ACSL1_HUMAN Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Acyl-CoA synthetase 1) (ACS1) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 1) (LACS 1) (Long-chain acyl-CoA synthetase 2) (LACS 2) (Long-chain fatty acid-CoA ligase 2) (Palmitoyl-CoA ligase 1) (Palmitoyl-CoA ligase 2) (Phytanate--CoA ligase) (EC 6.2.1.24) ACSL1 FACL1 FACL2 LACS LACS1 LACS2 Homo sapiens (Human) adiponectin-activated signaling pathway [GO:0033211]; fatty acid transport [GO:0015908]; lipid biosynthetic process [GO:0008610]; long-chain fatty acid import into cell [GO:0044539]; long-chain fatty acid metabolic process [GO:0001676]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of long-chain fatty acid import across plasma membrane [GO:0010747]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; response to nutrient [GO:0007584]; response to oleic acid [GO:0034201]; response to organic cyclic compound [GO:0014070]; triglyceride biosynthetic process [GO:0019432]; very long-chain fatty acid metabolic process [GO:0000038]; xenobiotic catabolic process [GO:0042178] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; peroxisomal membrane [GO:0005778]; plasma membrane [GO:0005886] arachidonate-CoA ligase activity [GO:0047676]; ATP binding [GO:0005524]; long-chain fatty acid-CoA ligase activity [GO:0004467]; oleoyl-CoA ligase activity [GO:0090434]; phytanate-CoA ligase activity [GO:0050197]; pristanate-CoA ligase activity [GO:0070251] 0.78847 0.24993 NIVSDCSAFVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.94439 0 0 0 0 0 0 P33151 CADH5_HUMAN Cadherin-5 (7B4 antigen) (Vascular endothelial cadherin) (VE-cadherin) (CD antigen CD144) CDH5 Homo sapiens (Human) adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; blood vessel endothelial cell migration [GO:0043534]; blood vessel maturation [GO:0001955]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intracellular calcium ion homeostasis [GO:0006874]; maintenance of blood-brain barrier [GO:0035633]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of inflammatory response [GO:0050728]; negative regulation of microtubule polymerization [GO:0031115]; positive regulation of angiogenesis [GO:0045766]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell migration [GO:0030335]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of gene expression [GO:0010628]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein-containing complex assembly [GO:0031334]; protein localization to bicellular tight junction [GO:1902396]; regulation of establishment of cell polarity [GO:2000114]; regulation of protein phosphorylation [GO:0001932]; regulation of vascular permeability [GO:0043114]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vasculature development [GO:0001944] adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; external side of plasma membrane [GO:0009897]; membrane [GO:0016020]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] beta-catenin binding [GO:0008013]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; signaling receptor binding [GO:0005102]; transmembrane transporter binding [GO:0044325]; vascular endothelial growth factor receptor 2 binding [GO:0043184] 0.92286 -1.056 SLDREKQAR 0 9.45162 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.92952 0 0 0 0 0 0 0 P33176 KINH_HUMAN Kinesin-1 heavy chain (Conventional kinesin heavy chain) (Ubiquitous kinesin heavy chain) (UKHC) KIF5B KNS KNS1 Homo sapiens (Human) "anterograde axonal protein transport [GO:0099641]; anterograde dendritic transport of neurotransmitter receptor complex [GO:0098971]; anterograde neuronal dense core vesicle transport [GO:1990048]; axon guidance [GO:0007411]; cellular response to type II interferon [GO:0071346]; centrosome localization [GO:0051642]; cytoplasm organization [GO:0007028]; lysosome localization [GO:0032418]; microtubule-based movement [GO:0007018]; mitochondrion transport along microtubule [GO:0047497]; mitocytosis [GO:0160040]; natural killer cell mediated cytotoxicity [GO:0042267]; plus-end-directed vesicle transport along microtubule [GO:0072383]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of membrane potential [GO:0042391]; retrograde neuronal dense core vesicle transport [GO:1990049]; stress granule disassembly [GO:0035617]; synaptic vesicle transport [GO:0048489]; vesicle transport along microtubule [GO:0047496]" axon cytoplasm [GO:1904115]; centriolar satellite [GO:0034451]; ciliary rootlet [GO:0035253]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; kinesin complex [GO:0005871]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; vesicle [GO:0031982] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777]; plus-end-directed microtubule motor activity [GO:0008574]; protein-containing complex binding [GO:0044877] 0.96923 -3.0281 ALESALKEAK 0 0 0 11.0819 10.6797 11.2931 0 0 0 0 10.4459 9.20504 0 10.0352 0 0 0 10.5444 0 0 0 0 0 0 0 0 0 P33260 CP2CI_HUMAN Cytochrome P450 2C18 (EC 1.14.14.1) (CYPIIC18) (Cytochrome P450-6b/29c) CYP2C18 Homo sapiens (Human) epoxygenase P450 pathway [GO:0019373]; linoleic acid metabolic process [GO:0043651]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]; xenobiotic metabolic process [GO:0006805] cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886] "arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; linoleic acid epoxygenase activity [GO:0071614]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; oxygen binding [GO:0019825]; retinoic acid 4-hydroxylase activity [GO:0008401]" 0.84797 0.1264 EFPNPEMFDPGHFLDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.60888 0 0 0 0 0 0 0 0 0 0 0 0 P33261 CP2CJ_HUMAN Cytochrome P450 2C19 (EC 1.14.14.1) ((R)-limonene 6-monooxygenase) (EC 1.14.14.53) ((S)-limonene 6-monooxygenase) (EC 1.14.14.51) ((S)-limonene 7-monooxygenase) (EC 1.14.14.52) (CYPIIC17) (CYPIIC19) (Cytochrome P450-11A) (Cytochrome P450-254C) (Fenbendazole monooxygenase (4'-hydroxylating)) (EC 1.14.14.75) (Mephenytoin 4-hydroxylase) CYP2C19 Homo sapiens (Human) epoxygenase P450 pathway [GO:0019373]; heterocycle metabolic process [GO:0046483]; long-chain fatty acid metabolic process [GO:0001676]; monoterpenoid metabolic process [GO:0016098]; omega-hydroxylase P450 pathway [GO:0097267]; steroid metabolic process [GO:0008202]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805] cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886] "(R)-limonene 6-monooxygenase activity [GO:0052741]; (S)-limonene 6-monooxygenase activity [GO:0018675]; (S)-limonene 7-monooxygenase activity [GO:0018676]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; long-chain fatty acid omega-1 hydroxylase activity [GO:0120319]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; oxygen binding [GO:0019825]; steroid hydroxylase activity [GO:0008395]" 0.95263 -1.4585 FSLMTLRNFGMGKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3568 0 0 P33402 GCYA2_HUMAN Guanylate cyclase soluble subunit alpha-2 (GCS-alpha-2) (EC 4.6.1.2) GUCY1A2 GUC1A2 GUCSA2 Homo sapiens (Human) cGMP-mediated signaling [GO:0019934]; nitric oxide mediated signal transduction [GO:0007263]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; response to oxygen levels [GO:0070482]; signal transduction [GO:0007165] "cytosol [GO:0005829]; guanylate cyclase complex, soluble [GO:0008074]" GTP binding [GO:0005525]; guanylate cyclase activity [GO:0004383]; heme binding [GO:0020037] 0.81775 0.22048 EESFTFIPR 0 0 0 0 0 0 0 0 0 0 0 0 9.29294 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P33527 MRP1_HUMAN Multidrug resistance-associated protein 1 (EC 7.6.2.2) (ATP-binding cassette sub-family C member 1) (Glutathione-S-conjugate-translocating ATPase ABCC1) (EC 7.6.2.3) (Leukotriene C(4) transporter) (LTC4 transporter) ABCC1 MRP MRP1 Homo sapiens (Human) carboxylic acid transmembrane transport [GO:1905039]; cell chemotaxis [GO:0060326]; cellular response to amyloid-beta [GO:1904646]; cellular response to oxidative stress [GO:0034599]; cobalamin transport [GO:0015889]; cyclic nucleotide transport [GO:0070729]; export across plasma membrane [GO:0140115]; glutathione transmembrane transport [GO:0034775]; heme catabolic process [GO:0042167]; leukotriene metabolic process [GO:0006691]; leukotriene transport [GO:0071716]; phospholipid translocation [GO:0045332]; positive regulation of inflammatory response [GO:0050729]; response to xenobiotic stimulus [GO:0009410]; sphingolipid translocation [GO:0099039]; transepithelial transport [GO:0070633]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; xenobiotic metabolic process [GO:0006805]; xenobiotic transport [GO:0042908]; xenobiotic transport across blood-brain barrier [GO:1990962] apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; extracellular exosome [GO:0070062]; lateral plasma membrane [GO:0016328]; membrane [GO:0016020]; plasma membrane [GO:0005886] ABC-type glutathione S-conjugate transporter activity [GO:0015431]; ABC-type transporter activity [GO:0140359]; ABC-type vitamin B12 transporter activity [GO:0015420]; ABC-type xenobiotic transporter activity [GO:0008559]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled inorganic anion transmembrane transporter activity [GO:0043225]; ATPase-coupled lipid transmembrane transporter activity [GO:0034040]; ATPase-coupled transmembrane transporter activity [GO:0042626]; carboxylic acid transmembrane transporter activity [GO:0046943]; efflux transmembrane transporter activity [GO:0015562]; glutathione transmembrane transporter activity [GO:0034634]; xenobiotic transmembrane transporter activity [GO:0042910] 0.95961 -1.8891 AEAKKEETWK 0 0 0 0 0 0 0 0 0 0 10.6168 0 0 0 0 0 0 0 10.1584 9.47405 0 9.63824 0 0 0 0 0 P33763 S10A5_HUMAN Protein S100-A5 (Protein S-100D) (S100 calcium-binding protein A5) S100A5 S100D Homo sapiens (Human) neuronal cell body [GO:0043025]; nucleus [GO:0005634] calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270] 0.84945 0.11547 SLDKNSDQEIDFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.88813 0 P33908 MA1A1_HUMAN "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA (EC 3.2.1.113) (Man(9)-alpha-mannosidase) (Man9-mannosidase) (Mannosidase alpha class 1A member 1) (Processing alpha-1,2-mannosidase IA) (Alpha-1,2-mannosidase IA)" MAN1A1 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; Golgi apparatus mannose trimming [GO:1904381]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; N-glycan processing [GO:0006491]; protein glycosylation [GO:0006486]; protein targeting to ER [GO:0045047]; ubiquitin-dependent ERAD pathway [GO:0030433] cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020] "calcium ion binding [GO:0005509]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [GO:0004571]" 0.50723 0.6064 AVELGVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.81437 0 0 0 0 P33991 MCM4_HUMAN DNA replication licensing factor MCM4 (EC 3.6.4.12) (CDC21 homolog) (P1-CDC21) MCM4 CDC21 Homo sapiens (Human) DNA replication [GO:0006260]; DNA strand elongation involved in DNA replication [GO:0006271]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via break-induced replication [GO:0000727]; mitotic DNA replication initiation [GO:1902975]; regulation of DNA-templated DNA replication initiation [GO:0030174] "chromosome, telomeric region [GO:0000781]; CMG complex [GO:0071162]; MCM complex [GO:0042555]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]" ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA helicase activity [GO:0003678]; single-stranded DNA binding [GO:0003697] 0.95981 -1.8502 GSSAVGLTAYVMKDPETR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0863 0 0 0 0 0 0 0 0 0 11.2564 11.0647 P33993 MCM7_HUMAN DNA replication licensing factor MCM7 (EC 3.6.4.12) (CDC47 homolog) (P1.1-MCM3) MCM7 CDC47 MCM2 Homo sapiens (Human) cell cycle [GO:0007049]; cell population proliferation [GO:0008283]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to organic substance [GO:0071310]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response [GO:0006974]; DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; DNA strand elongation involved in DNA replication [GO:0006271]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via break-induced replication [GO:0000727]; regulation of DNA-templated DNA replication initiation [GO:0030174]; regulation of phosphorylation [GO:0042325] "chromatin [GO:0000785]; chromosome, telomeric region [GO:0000781]; CMG complex [GO:0071162]; cytosol [GO:0005829]; MCM complex [GO:0042555]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]" ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA helicase activity [GO:0003678]; single-stranded DNA binding [GO:0003697] 0.91403 -0.76129 CSILAAANPAYGRYNPR 0 0 0 0 0 0 0 0 0 0 0 0 14.8411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P34059 GALNS_HUMAN N-acetylgalactosamine-6-sulfatase (EC 3.1.6.4) (Chondroitinsulfatase) (Chondroitinase) (Galactose-6-sulfate sulfatase) (GalN6S) (N-acetylgalactosamine-6-sulfate sulfatase) (GalNAc6S sulfatase) GALNS Homo sapiens (Human) azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202] arylsulfatase activity [GO:0004065]; metal ion binding [GO:0046872]; N-acetylgalactosamine-4-sulfatase activity [GO:0003943]; N-acetylgalactosamine-6-sulfatase activity [GO:0043890]; sulfuric ester hydrolase activity [GO:0008484] 0.86763 0.07019 FPLSFASAEYQEALSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.78174 0 0 0 9.2946 0 0 0 P34096 RNAS4_HUMAN Ribonuclease 4 (RNase 4) (EC 3.1.27.-) RNASE4 RNS4 Homo sapiens (Human) defense response to Gram-positive bacterium [GO:0050830]; mRNA cleavage [GO:0006379]; RNA phosphodiester bond hydrolysis [GO:0090501] extracellular region [GO:0005576]; extracellular space [GO:0005615] nucleic acid binding [GO:0003676]; ribonuclease A activity [GO:0004522]; RNA nuclease activity [GO:0004540] 0.93937 -1.3042 VTDCRDTGSSRAPNCR 0 10.0685 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5369 0 0 P34130 NTF4_HUMAN Neurotrophin-4 (NT-4) (Neurotrophin-5) (NT-5) (Neutrophic factor 4) NTF4 NTF5 Homo sapiens (Human) adult locomotory behavior [GO:0008344]; epidermis development [GO:0008544]; ganglion mother cell fate determination [GO:0007402]; innervation [GO:0060384]; long-term memory [GO:0007616]; mechanoreceptor differentiation [GO:0042490]; memory [GO:0007613]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; nerve growth factor signaling pathway [GO:0038180]; neuron projection morphogenesis [GO:0048812]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; regulation of neuron differentiation [GO:0045664]; sensory organ boundary specification [GO:0008052]; taste bud development [GO:0061193]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] extracellular region [GO:0005576]; synaptic vesicle [GO:0008021] growth factor activity [GO:0008083]; nerve growth factor receptor binding [GO:0005163] 0.88429 -0.13136 RGELAVCDAVSGWVTDRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5278 P34741 SDC2_HUMAN Syndecan-2 (SYND2) (Fibroglycan) (Heparan sulfate proteoglycan core protein) (HSPG) (CD antigen CD362) SDC2 HSPG1 Homo sapiens (Human) cell migration [GO:0016477]; dendrite morphogenesis [GO:0048813]; regulation of dendrite morphogenesis [GO:0048814] cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; Golgi lumen [GO:0005796]; lysosomal lumen [GO:0043202]; plasma membrane [GO:0005886] identical protein binding [GO:0042802]; PDZ domain binding [GO:0030165] 0.63056 0.39844 AELTSDK 0 0 0 0 0 0 0 0 0 0 9.56596 0 0 0 0 0 0 8.32908 8.99492 0 0 0 8.05902 0 0 0 0 P34897 GLYM_HUMAN "Serine hydroxymethyltransferase, mitochondrial (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase)" SHMT2 Homo sapiens (Human) folic acid metabolic process [GO:0046655]; glycine biosynthetic process from serine [GO:0019264]; glycine metabolic process [GO:0006544]; L-serine biosynthetic process [GO:0006564]; L-serine catabolic process [GO:0006565]; L-serine metabolic process [GO:0006563]; one-carbon metabolic process [GO:0006730]; positive regulation of cell population proliferation [GO:0008284]; protein homotetramerization [GO:0051289]; protein K63-linked deubiquitination [GO:0070536]; protein tetramerization [GO:0051262]; purine nucleobase biosynthetic process [GO:0009113]; regulation of aerobic respiration [GO:1903715]; regulation of mitochondrial translation [GO:0070129]; regulation of oxidative phosphorylation [GO:0002082]; response to type I interferon [GO:0034340]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653] BRISC complex [GO:0070552]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule cytoskeleton [GO:0015630]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; nucleus [GO:0005634] chromatin binding [GO:0003682]; glycine hydroxymethyltransferase activity [GO:0004372]; L-allo-threonine aldolase activity [GO:0008732]; mRNA 5'-UTR binding [GO:0048027]; mRNA regulatory element binding translation repressor activity [GO:0000900]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; serine binding [GO:0070905]; zinc ion binding [GO:0008270] 0.88315 -0.17809 GLELIASENFCSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6937 9.91409 0 P34931 HS71L_HUMAN Heat shock 70 kDa protein 1-like (Heat shock 70 kDa protein 1L) (Heat shock 70 kDa protein 1-Hom) (HSP70-Hom) HSPA1L Homo sapiens (Human) binding of sperm to zona pellucida [GO:0007339]; chaperone cofactor-dependent protein refolding [GO:0051085]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein refolding [GO:0042026]; response to unfolded protein [GO:0006986] blood microparticle [GO:0072562]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; zona pellucida receptor complex [GO:0002199] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; heat shock protein binding [GO:0031072]; protein folding chaperone [GO:0044183]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082] 0.87185 0.050777 AFYPEEISSMVLTK 0 0 9.31771 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P34932 HSP74_HUMAN Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) HSPA4 APG2 Homo sapiens (Human) chaperone-mediated protein complex assembly [GO:0051131]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; response to unfolded protein [GO:0006986] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP-dependent protein folding chaperone [GO:0140662] 0.91735 -0.86213 AFSDPFVEAEK 8.53691 10.0783 9.51213 0 0 0 0 10.5484 10.4476 0 0 9.14139 0 0 0 0 0 0 0 0 0 10.761 0 10.1767 10.2854 10.5077 10.432 P34947 GRK5_HUMAN G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK5) GRK5 GPRK5 Homo sapiens (Human) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; apoptotic process [GO:0006915]; fat cell differentiation [GO:0045444]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; regulation of signal transduction [GO:0009966]; tachykinin receptor signaling pathway [GO:0007217]; Wnt signaling pathway [GO:0016055] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; beta-adrenergic receptor kinase activity [GO:0047696]; G protein-coupled receptor kinase activity [GO:0004703]; phospholipid binding [GO:0005543]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein serine/threonine kinase activity [GO:0004674] 0.84274 0.15073 FLQWKWLER 0 9.25165 0 0 0 0 0 0 0 0 0 10.3742 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P34969 5HT7R_HUMAN 5-hydroxytryptamine receptor 7 (5-HT-7) (5-HT7) (5-HT-X) (Serotonin receptor 7) HTR7 Homo sapiens (Human) "blood circulation [GO:0008015]; chemical synaptic transmission [GO:0007268]; circadian rhythm [GO:0007623]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; smooth muscle contraction [GO:0006939]; vasoconstriction [GO:0042310]" dendrite [GO:0030425]; plasma membrane [GO:0005886]; synapse [GO:0045202]; trans-Golgi network membrane [GO:0032588] G protein-coupled serotonin receptor activity [GO:0004993]; neurotransmitter receptor activity [GO:0030594] 0.60191 0.44065 SLLQCQYR 0 0 0 0 0 0 0 0 0 0 0 0 9.44857 0 0 10.3262 10.6786 10.6785 10.6871 0 9.5878 0 0 9.93456 10.8082 10.774 11.3256 P34995 PE2R1_HUMAN Prostaglandin E2 receptor EP1 subtype (PGE receptor EP1 subtype) (PGE2 receptor EP1 subtype) (Prostanoid EP1 receptor) PTGER1 Homo sapiens (Human) adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; response to lipopolysaccharide [GO:0032496] plasma membrane [GO:0005886] D1 dopamine receptor binding [GO:0031748]; prostaglandin E receptor activity [GO:0004957] 0.72929 0.33906 SASASSASSIASASTFFGGSRSSGSAR 0 0 0 0 0 0 0 0 0 0 0 10.0884 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P35052 GPC1_HUMAN Glypican-1 [Cleaved into: Secreted glypican-1] GPC1 Homo sapiens (Human) cell migration [GO:0016477]; heparan sulfate proteoglycan catabolic process [GO:0030200]; myelin assembly [GO:0032288]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; positive regulation of skeletal muscle cell differentiation [GO:2001016]; regulation of protein localization to membrane [GO:1905475]; Schwann cell differentiation [GO:0014037] cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; lysosomal lumen [GO:0043202]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; synapse [GO:0045202] copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; laminin binding [GO:0043236] 0.8083 0.23082 VIQGCGNPKVNPQGPGPEEK 0 0 0 0 0 0 0 11.1232 0 0 0 0 0 0 0 0 11.2074 0 0 0 0 0 0 0 0 0 0 P35080 PROF2_HUMAN Profilin-2 (Profilin II) PFN2 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; modification of postsynaptic actin cytoskeleton [GO:0098885]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of ruffle assembly [GO:1900028]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of ATP-dependent activity [GO:0032781]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of stress fiber assembly [GO:0051496]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein stabilization [GO:0050821]; regulation of actin filament polymerization [GO:0030833]; regulation of synaptic vesicle exocytosis [GO:2000300] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; postsynapse [GO:0098794]; presynapse [GO:0098793]; Schaffer collateral - CA1 synapse [GO:0098685] "actin binding [GO:0003779]; actin monomer binding [GO:0003785]; ATP hydrolysis activity [GO:0016887]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]" 0.88021 -0.030959 SQGGEPTYNVAVGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.66178 0 0 0 0 0 0 0 0 0 8.87258 P35221 CTNA1_HUMAN Catenin alpha-1 (Alpha E-catenin) (Cadherin-associated protein) (Renal carcinoma antigen NY-REN-13) CTNNA1 Homo sapiens (Human) aging [GO:0007568]; apical junction assembly [GO:0043297]; axon regeneration [GO:0031103]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cellular response to indole-3-methanol [GO:0071681]; epithelial cell-cell adhesion [GO:0090136]; establishment or maintenance of cell polarity [GO:0007163]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; gap junction assembly [GO:0016264]; integrin-mediated signaling pathway [GO:0007229]; male gonad development [GO:0008584]; negative regulation of cell motility [GO:2000146]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of integrin-mediated signaling pathway [GO:2001045]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of protein localization to nucleus [GO:1900181]; neuroblast proliferation [GO:0007405]; odontogenesis of dentin-containing tooth [GO:0042475]; ovarian follicle development [GO:0001541]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization [GO:0008104]; response to estrogen [GO:0043627]; smoothened signaling pathway [GO:0007224] acrosomal vesicle [GO:0001669]; actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; flotillin complex [GO:0016600]; focal adhesion [GO:0005925]; intercalated disc [GO:0014704]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886]; zonula adherens [GO:0005915] actin filament binding [GO:0051015]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; gamma-catenin binding [GO:0045295]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; vinculin binding [GO:0017166] 0.91658 -0.84458 ALKPEVDK 0 0 0 0 9.39973 0 0 8.65628 0 14.1272 0 11.4216 0 0 9.09141 0 0 13.4458 0 0 0 0 9.81298 0 10.869 10.0802 9.24824 P35222 CTNB1_HUMAN Catenin beta-1 (Beta-catenin) CTNNB1 CTNNB OK/SW-cl.35 PRO2286 Homo sapiens (Human) "acinar cell differentiation [GO:0090425]; adherens junction assembly [GO:0034333]; anterior/posterior axis specification [GO:0009948]; apoptotic signaling pathway [GO:0097190]; astrocyte-dopaminergic neuron signaling [GO:0036520]; bone resorption [GO:0045453]; branching involved in blood vessel morphogenesis [GO:0001569]; branching involved in ureteric bud morphogenesis [GO:0001658]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation [GO:0044338]; canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904954]; canonical Wnt signaling pathway involved in negative regulation of apoptotic process [GO:0044336]; canonical Wnt signaling pathway involved in osteoblast differentiation [GO:0044339]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition [GO:0044334]; cell adhesion [GO:0007155]; cell fate specification [GO:0001708]; cell maturation [GO:0048469]; cell morphogenesis involved in differentiation [GO:0000904]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; cellular response to growth factor stimulus [GO:0071363]; cellular response to indole-3-methanol [GO:0071681]; central nervous system vasculogenesis [GO:0022009]; chemical synaptic transmission [GO:0007268]; chondrocyte differentiation [GO:0002062]; cranial ganglion development [GO:0061550]; cranial skeletal system development [GO:1904888]; detection of muscle stretch [GO:0035995]; dorsal root ganglion development [GO:1990791]; dorsal/ventral axis specification [GO:0009950]; ectoderm development [GO:0007398]; embryonic axis specification [GO:0000578]; embryonic brain development [GO:1990403]; embryonic digit morphogenesis [GO:0042733]; embryonic foregut morphogenesis [GO:0048617]; embryonic forelimb morphogenesis [GO:0035115]; embryonic heart tube development [GO:0035050]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic skeletal limb joint morphogenesis [GO:0036023]; endodermal cell fate commitment [GO:0001711]; endothelial tube morphogenesis [GO:0061154]; epithelial cell differentiation involved in prostate gland development [GO:0060742]; epithelial cell proliferation involved in prostate gland development [GO:0060767]; epithelial to mesenchymal transition [GO:0001837]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment of blood-brain barrier [GO:0060856]; establishment of blood-retinal barrier [GO:1990963]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fungiform papilla formation [GO:0061198]; gastrulation with mouth forming second [GO:0001702]; genitalia morphogenesis [GO:0035112]; glial cell fate determination [GO:0007403]; hair cell differentiation [GO:0035315]; hair follicle morphogenesis [GO:0031069]; hair follicle placode formation [GO:0060789]; hindbrain development [GO:0030902]; hypothalamus development [GO:0021854]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; in utero embryonic development [GO:0001701]; layer formation in cerebral cortex [GO:0021819]; lens morphogenesis in camera-type eye [GO:0002089]; lung epithelial cell differentiation [GO:0060487]; lung induction [GO:0060492]; lung-associated mesenchyme development [GO:0060484]; male genitalia development [GO:0030539]; MAPK cascade [GO:0000165]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesenchymal stem cell differentiation [GO:0072497]; metanephros morphogenesis [GO:0003338]; midbrain dopaminergic neuron differentiation [GO:1904948]; myoblast proliferation [GO:0051450]; negative regulation of angiogenesis [GO:0016525]; negative regulation of apoptotic process [GO:0043066]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003340]; negative regulation of mitotic cell cycle, embryonic [GO:0045976]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nephron tubule formation [GO:0072079]; neural plate development [GO:0001840]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron migration [GO:0001764]; neuron projection extension [GO:1990138]; odontogenesis of dentin-containing tooth [GO:0042475]; oligodendrocyte differentiation [GO:0048709]; oocyte development [GO:0048599]; osteoclast differentiation [GO:0030316]; oviduct development [GO:0060066]; pancreas development [GO:0031016]; positive regulation of apoptotic process [GO:0043065]; positive regulation of branching involved in lung morphogenesis [GO:0061047]; positive regulation of cell differentiation [GO:0045597]; positive regulation of core promoter binding [GO:1904798]; positive regulation of determination of dorsal identity [GO:2000017]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of epithelial cell proliferation involved in prostate gland development [GO:0060769]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743]; positive regulation of gene expression [GO:0010628]; positive regulation of heparan sulfate proteoglycan biosynthetic process [GO:0010909]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of myoblast proliferation [GO:2000288]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein localization to cell surface [GO:0034394]; protein polyubiquitination [GO:0000209]; proximal/distal pattern formation [GO:0009954]; regulation of angiogenesis [GO:0045765]; regulation of calcium ion import [GO:0090279]; regulation of centriole-centriole cohesion [GO:0030997]; regulation of centromeric sister chromatid cohesion [GO:0070602]; regulation of fibroblast proliferation [GO:0048145]; regulation of myelination [GO:0031641]; regulation of nephron tubule epithelial cell differentiation [GO:0072182]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to cell surface [GO:2000008]; regulation of protein ubiquitination [GO:0031396]; regulation of secondary heart field cardioblast proliferation [GO:0003266]; regulation of smooth muscle cell proliferation [GO:0048660]; regulation of synapse assembly [GO:0051963]; regulation of T cell proliferation [GO:0042129]; regulation of timing of anagen [GO:0051884]; renal inner medulla development [GO:0072053]; renal outer medulla development [GO:0072054]; renal vesicle formation [GO:0072033]; response to estradiol [GO:0032355]; response to xenobiotic stimulus [GO:0009410]; smooth muscle cell differentiation [GO:0051145]; stem cell population maintenance [GO:0019827]; stem cell proliferation [GO:0072089]; sympathetic ganglion development [GO:0061549]; synapse organization [GO:0050808]; synaptic vesicle clustering [GO:0097091]; synaptic vesicle transport [GO:0048489]; T cell differentiation in thymus [GO:0033077]; thymus development [GO:0048538]; trachea formation [GO:0060440]; transcription by RNA polymerase II [GO:0006366]" "adherens junction [GO:0005912]; apical part of cell [GO:0045177]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; beta-catenin destruction complex [GO:0030877]; beta-catenin-ICAT complex [GO:1990711]; beta-catenin-TCF complex [GO:1990907]; beta-catenin-TCF7L2 complex [GO:0070369]; bicellular tight junction [GO:0005923]; catenin complex [GO:0016342]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell-cell junction [GO:0005911]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; extracellular exosome [GO:0070062]; fascia adherens [GO:0005916]; flotillin complex [GO:0016600]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; membrane [GO:0016020]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic membrane [GO:0045211]; presynaptic active zone cytoplasmic component [GO:0098831]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; Schaffer collateral - CA1 synapse [GO:0098685]; Scrib-APC-beta-catenin complex [GO:0034750]; spindle pole [GO:0000922]; synapse [GO:0045202]; transcription regulator complex [GO:0005667]; Wnt signalosome [GO:1990909]; Z disc [GO:0030018]" alpha-catenin binding [GO:0045294]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA-binding transcription factor binding [GO:0140297]; enzyme binding [GO:0019899]; histone methyltransferase binding [GO:1990226]; I-SMAD binding [GO:0070411]; kinase binding [GO:0019900]; nuclear estrogen receptor binding [GO:0030331]; nuclear receptor binding [GO:0016922]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; SMAD binding [GO:0046332]; transcription coactivator activity [GO:0003713]; transcription coregulator binding [GO:0001221]; transcription corepressor binding [GO:0001222]; transmembrane transporter binding [GO:0044325]; ubiquitin protein ligase binding [GO:0031625] 0.88496 -0.12947 AGDREDITEPAICALR 0 0 0 0 0 0 0 0 0 0 0 0 9.69443 0 0 0 0 0 9.53683 0 0 0 9.1555 0 0 0 0 P35226 BMI1_HUMAN Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51) BMI1 PCGF4 RNF51 Homo sapiens (Human) "apoptotic signaling pathway [GO:0097190]; brain development [GO:0007420]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to interleukin-1 [GO:0071347]; chromatin remodeling [GO:0006338]; DNA methylation [GO:0006306]; embryonic skeletal system morphogenesis [GO:0048704]; hemopoiesis [GO:0030097]; histone acetylation [GO:0016573]; histone H2A-K119 monoubiquitination [GO:0036353]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of immature T cell proliferation in thymus [GO:0033092]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; regulation of adaxial/abaxial pattern formation [GO:2000011]; regulation of gene expression [GO:0010468]; regulation of kidney development [GO:0090183]; rostrocaudal neural tube patterning [GO:0021903]; segment specification [GO:0007379]; somatic stem cell division [GO:0048103]" cytosol [GO:0005829]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PcG protein complex [GO:0031519]; PRC1 complex [GO:0035102]; ubiquitin ligase complex [GO:0000151] promoter-specific chromatin binding [GO:1990841]; RING-like zinc finger domain binding [GO:0071535]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; ubiquitin-protein transferase activator activity [GO:0097027]; zinc ion binding [GO:0008270] 0.95601 -1.5871 MKISHQR 0 0 0 0 0 0 0 0 0 10.4746 10.5736 0 0 0 0 0 0 0 0 0 0 0 9.77309 0 0 0 0 P35227 PCGF2_HUMAN Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) PCGF2 MEL18 RNF110 ZNF144 Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; apoptotic signaling pathway [GO:0097190]; cellular response to hydrogen peroxide [GO:0070301]; chromatin remodeling [GO:0006338]; embryonic skeletal system morphogenesis [GO:0048704]; histone acetylation [GO:0016573]; histone H2A-K119 monoubiquitination [GO:0036353]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of transcription by RNA polymerase II [GO:0000122] chromatin [GO:0000785]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PcG protein complex [GO:0031519]; PRC1 complex [GO:0035102]; sex chromatin [GO:0001739] DNA binding [GO:0003677]; metal ion binding [GO:0046872]; promoter-specific chromatin binding [GO:1990841] 0.96389 -2.2133 NGPLPLKYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4488 0 0 0 0 0 0 0 0 0 P35228 NOS2_HUMAN "Nitric oxide synthase, inducible (EC 1.14.13.39) (Hepatocyte NOS) (HEP-NOS) (Inducible NO synthase) (Inducible NOS) (iNOS) (NOS type II) (Peptidyl-cysteine S-nitrosylase NOS2)" NOS2 NOS2A Homo sapiens (Human) arginine catabolic process [GO:0006527]; cell redox homeostasis [GO:0045454]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; cellular response to xenobiotic stimulus [GO:0071466]; circadian rhythm [GO:0007623]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; inflammatory response [GO:0006954]; innate immune response in mucosa [GO:0002227]; negative regulation of blood pressure [GO:0045776]; negative regulation of gene expression [GO:0010629]; negative regulation of protein catabolic process [GO:0042177]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of killing of cells of another organism [GO:0051712]; positive regulation of leukocyte mediated cytotoxicity [GO:0001912]; prostaglandin secretion [GO:0032310]; regulation of cell population proliferation [GO:0042127]; regulation of cellular respiration [GO:0043457]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of insulin secretion [GO:0050796]; response to bacterium [GO:0009617]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; superoxide metabolic process [GO:0006801] cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506] arginine binding [GO:0034618]; calmodulin binding [GO:0005516]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; nitric-oxide synthase activity [GO:0004517]; protein homodimerization activity [GO:0042803]; tetrahydrobiopterin binding [GO:0034617] 0.96203 -2.4779 AKGILTCR 0 0 0 0 0 0 0 0 12.3204 0 0 10.2146 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P35232 PHB1_HUMAN Prohibitin 1 PHB1 PHB Homo sapiens (Human) activation of phospholipase C activity [GO:0007202]; activation of protein kinase C activity [GO:1990051]; antiviral innate immune response [GO:0140374]; B cell activation [GO:0042113]; CD40 signaling pathway [GO:0023035]; cellular response to interleukin-6 [GO:0071354]; DNA biosynthetic process [GO:0071897]; epigenetic regulation of gene expression [GO:0040029]; mitochondrion organization [GO:0007005]; modulation by host of viral RNA genome replication [GO:0044830]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by competitive promoter binding [GO:0010944]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; positive regulation of cell death [GO:0010942]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; progesterone receptor signaling pathway [GO:0050847]; protein stabilization [GO:0050821]; regulation of apoptotic process [GO:0042981]; regulation of DNA-templated transcription [GO:0006355]; RIG-I signaling pathway [GO:0039529]; signal transduction [GO:0007165]; T-helper 17 type immune response [GO:0072538]; viral entry into host cell [GO:0046718] cell surface [GO:0009986]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial prohibitin complex [GO:0035632]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] complement component C3a binding [GO:0001850]; complement component C3b binding [GO:0001851]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; protein heterodimerization activity [GO:0046982]; proteinase activated receptor binding [GO:0031871]; transcription corepressor activity [GO:0003714] 0 7.8815 AAIISAEGDSK 12.3477 12.3627 11.9378 10.7844 11.1322 10.729 12.0678 12.1893 12.2474 0 12.4161 9.15086 11.7512 12.4741 12.8086 13.1068 12.3729 0 0 9.16777 11.314 0 8.45096 8.71637 11.608 9.66672 9.62359 P35237 SPB6_HUMAN Serpin B6 (Cytoplasmic antiproteinase) (CAP) (Peptidase inhibitor 6) (PI-6) (Placental thrombin inhibitor) SERPINB6 PI6 PTI Homo sapiens (Human) cellular response to osmotic stress [GO:0071470]; negative regulation of endopeptidase activity [GO:0010951]; sensory perception of sound [GO:0007605] collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; serine protease inhibitor complex [GO:0097180]; tertiary granule membrane [GO:0070821] protease binding [GO:0002020]; serine-type endopeptidase inhibitor activity [GO:0004867] 0.0079365 2.056 FCADHPFLFFIQHSK 0 0 0 0 0 0 0 0 0 0 0 0 0 12.3054 0 0 0 0 0 0 0 0 0 0 10.2051 10.0857 0 P35240 MERL_HUMAN Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomerlin) (Schwannomin) NF2 SCH Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; MAPK cascade [GO:0000165]; mesoderm formation [GO:0001707]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of Schwann cell proliferation [GO:0010626]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; osteoblast proliferation [GO:0033687]; positive regulation of cell differentiation [GO:0045597]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell shape [GO:0008360]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of organelle assembly [GO:1902115]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010] adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587] actin binding [GO:0003779]; integrin binding [GO:0005178] 0.96942 -4.0536 AGAIASRMSFSSLK 9.99067 0 9.6374 0 9.1133 0 9.13008 9.0072 8.9402 10.3835 0 0 9.48517 9.64703 0 9.82987 8.85084 9.00548 0 0 0 0 0 9.87664 0 10.5383 0 P35241 RADI_HUMAN Radixin RDX Homo sapiens (Human) apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization to plasma membrane [GO:0061951]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein localization to early endosome [GO:1902966]; protein kinase A signaling [GO:0010737]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of Rap protein signal transduction [GO:0032487]; regulation of ruffle assembly [GO:1900027] adherens junction [GO:0005912]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; plasma membrane [GO:0005886]; T-tubule [GO:0030315] actin binding [GO:0003779]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; protein kinase A binding [GO:0051018]; RNA binding [GO:0003723] 0.96922 -4.4841 AFAAQEDLEK 0 0 0 0 0 0 0 0 0 12.5666 8.99331 9.00907 9.35001 9.30456 0 0 0 0 0 11.4796 0 0 0 0 0 0 0 P35247 SFTPD_HUMAN Pulmonary surfactant-associated protein D (PSP-D) (SP-D) (Collectin-7) (Lung surfactant protein D) SFTPD COLEC7 PSPD SFTP4 Homo sapiens (Human) defense response to bacterium [GO:0042742]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont catalytic activity [GO:0052403]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129] clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791] carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802] 0.91142 -0.75156 GLAGPKGERGVPGER 17.2836 0 0 0 0 0 0 0 0 0 0 16.8382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P35250 RFC2_HUMAN Replication factor C subunit 2 (Activator 1 40 kDa subunit) (A1 40 kDa subunit) (Activator 1 subunit 2) (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40) RFC2 Homo sapiens (Human) DNA duplex unwinding [GO:0032508]; DNA repair [GO:0006281]; DNA-templated DNA replication [GO:0006261]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264] Ctf18 RFC-like complex [GO:0031390]; DNA replication factor C complex [GO:0005663]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA binding [GO:0003677]; enzyme binding [GO:0019899] 0.96929 -3.4253 FALACNASDKIIEPIQSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.84248 0 0 9.63379 0 0 0 8.99676 0 P35251 RFC1_HUMAN Replication factor C subunit 1 (Activator 1 140 kDa subunit) (A1 140 kDa subunit) (Activator 1 large subunit) (Activator 1 subunit 1) (DNA-binding protein PO-GA) (Replication factor C 140 kDa subunit) (RF-C 140 kDa subunit) (RFC140) (Replication factor C large subunit) RFC1 RFC140 Homo sapiens (Human) DNA repair [GO:0006281]; DNA-templated DNA replication [GO:0006261]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; telomere maintenance via telomerase [GO:0007004] cytoplasm [GO:0005737]; DNA replication factor C complex [GO:0005663]; Elg1 RFC-like complex [GO:0031391]; extracellular exosome [GO:0070062]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA binding [GO:0003677]; DNA clamp loader activity [GO:0003689]; DNA clamp unloader activity [GO:0061860]; double-stranded DNA binding [GO:0003690]; enzyme activator activity [GO:0008047]; protein domain specific binding [GO:0019904]; sequence-specific DNA binding [GO:0043565] 0.9695 -3.5868 HAAKFGKFSGK 0 0 0 10.189 10.0283 0 0 0 0 0 0 9.97599 0 0 0 0 0 0 9.4567 0 9.41739 0 0 0 0 10.9244 0 P35268 RL22_HUMAN Large ribosomal subunit protein eL22 (60S ribosomal protein L22) (EBER-associated protein) (EAP) (Epstein-Barr virus small RNA-associated protein) (Heparin-binding protein HBp15) RPL22 Homo sapiens (Human) alpha-beta T cell differentiation [GO:0046632]; cytoplasmic translation [GO:0002181]; translation [GO:0006412]; translation at presynapse [GO:0140236] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; nucleus [GO:0005634]; presynapse [GO:0098793]; ribonucleoprotein complex [GO:1990904] heparin binding [GO:0008201]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0 6.182 AGNLGGGVVTIER 9.01633 8.7761 0 0 0 0 10.3128 9.69333 10.3746 10.6604 10.4907 10.4434 9.53417 0 9.65301 9.64108 0 9.5328 0 0 0 0 0 0 9.84153 0 0 P35270 SPRE_HUMAN Sepiapterin reductase (SPR) (EC 1.1.1.153) SPR Homo sapiens (Human) nitric oxide biosynthetic process [GO:0006809]; tetrahydrobiopterin biosynthetic process [GO:0006729] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654] aldo-keto reductase (NADP) activity [GO:0004033]; NADP binding [GO:0050661]; sepiapterin reductase activity [GO:0004757] 0.95083 -1.4357 AVCLLTGASR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.487 0 0 0 0 0 0 0 0 0 0 0 0 P35318 ADML_HUMAN Pro-adrenomedullin [Cleaved into: Adrenomedullin (AM); Proadrenomedullin N-20 terminal peptide (ProAM N-terminal 20 peptide) (PAMP) (ProAM-N20)] ADM AM Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adrenomedullin receptor signaling pathway [GO:1990410]; aging [GO:0007568]; amylin receptor signaling pathway [GO:0097647]; androgen metabolic process [GO:0008209]; animal organ regeneration [GO:0031100]; antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; calcium ion homeostasis [GO:0055074]; cAMP-mediated signaling [GO:0019933]; cell population proliferation [GO:0008283]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; developmental growth [GO:0048589]; female pregnancy [GO:0007565]; G protein-coupled receptor internalization [GO:0002031]; heart development [GO:0007507]; hormone secretion [GO:0046879]; inflammatory response [GO:0006954]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of vascular permeability [GO:0043116]; negative regulation of vasoconstriction [GO:0045906]; neural tube closure [GO:0001843]; neuron projection regeneration [GO:0031102]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate [GO:0010460]; positive regulation of progesterone biosynthetic process [GO:2000184]; positive regulation of vasculogenesis [GO:2001214]; receptor internalization [GO:0031623]; regulation of systemic arterial blood pressure [GO:0003073]; regulation of the force of heart contraction [GO:0002026]; regulation of urine volume [GO:0035809]; response to cold [GO:0009409]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to insulin [GO:0032868]; response to lipopolysaccharide [GO:0032496]; response to starvation [GO:0042594]; response to wounding [GO:0009611]; signal transduction [GO:0007165]; spongiotrophoblast layer development [GO:0060712]; vascular associated smooth muscle cell development [GO:0097084]; vasculogenesis [GO:0001570] cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615] adrenomedullin receptor binding [GO:0031700]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102] 0.96757 -2.347 DKDNVAPRSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.827 0 0 0 0 0 0 0 P35346 SSR5_HUMAN Somatostatin receptor type 5 (SS-5-R) (SS5-R) (SS5R) (SST5) SSTR5 Homo sapiens (Human) "cellular response to glucocorticoid stimulus [GO:0071385]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; glucose homeostasis [GO:0042593]; negative regulation of cell population proliferation [GO:0008285]; neuropeptide signaling pathway [GO:0007218]; positive regulation of cytokinesis [GO:0032467]; regulation of insulin secretion [GO:0050796]" neuron projection [GO:0043005]; plasma membrane [GO:0005886] somatostatin receptor activity [GO:0004994] 0.72779 0.34989 VLCLRKGSGAK 0 0 0 0 0 0 0 0 8.83033 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P35354 PGH2_HUMAN Prostaglandin G/H synthase 2 (EC 1.14.99.1) (Cyclooxygenase-2) (COX-2) (PHS II) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (Prostaglandin-endoperoxide synthase 2) PTGS2 COX2 Homo sapiens (Human) "aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; learning [GO:0007612]; maintenance of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; prostaglandin secretion [GO:0032310]; regulation of blood pressure [GO:0008217]; regulation of inflammatory response [GO:0050727]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to nematode [GO:0009624]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]" caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; nuclear inner membrane [GO:0005637]; nuclear outer membrane [GO:0005640]; protein-containing complex [GO:0032991] "enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]" 0 12.66 QLPDSNEIVEK 9.66422 0 8.59294 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P35398 RORA_HUMAN Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha) (Nuclear receptor subfamily 1 group F member 1) (RAR-related orphan receptor A) (Retinoid-related orphan receptor-alpha) RORA NR1F1 RZRA Homo sapiens (Human) angiogenesis [GO:0001525]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to sterol [GO:0036315]; cellular response to tumor necrosis factor [GO:0071356]; cerebellar granule cell precursor proliferation [GO:0021930]; cerebellar Purkinje cell differentiation [GO:0021702]; cGMP metabolic process [GO:0046068]; cholesterol homeostasis [GO:0042632]; circadian regulation of gene expression [GO:0032922]; intracellular receptor signaling pathway [GO:0030522]; muscle cell differentiation [GO:0042692]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of DNA-templated transcription [GO:0006355]; regulation of glucose metabolic process [GO:0010906]; regulation of macrophage activation [GO:0043030]; regulation of smoothened signaling pathway [GO:0008589]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription by RNA polymerase II [GO:0006357]; T-helper 17 cell differentiation [GO:0072539]; triglyceride homeostasis [GO:0070328]; xenobiotic metabolic process [GO:0006805] chromatin [GO:0000785]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "beta-catenin binding [GO:0008013]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; transcription coactivator binding [GO:0001223]; transcription coregulator binding [GO:0001221]; transcription corepressor binding [GO:0001222]; zinc ion binding [GO:0008270]" 0.96893 -3.0105 ALCGRHTEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.64351 0 10.4333 0 0 P35442 TSP2_HUMAN Thrombospondin-2 THBS2 TSP2 Homo sapiens (Human) cell adhesion [GO:0007155]; negative regulation of angiogenesis [GO:0016525]; positive regulation of synapse assembly [GO:0051965] basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091] calcium ion binding [GO:0005509]; heparin binding [GO:0008201] 0.92323 -1.1649 EGFFLTAQLKQDGKSR 0 0 0 0 0 0 0 0 0 0 9.94572 0 0 0 0 0 0 0 0 0 11.2156 0 0 0 0 0 0 P35443 TSP4_HUMAN Thrombospondin-4 THBS4 TSP4 Homo sapiens (Human) behavioral response to pain [GO:0048266]; endothelial cell-cell adhesion [GO:0071603]; myoblast migration [GO:0051451]; negative regulation of angiogenesis [GO:0016525]; positive regulation of cell division [GO:0051781]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of tissue remodeling [GO:0034103]; response to endoplasmic reticulum stress [GO:0034976]; response to unfolded protein [GO:0006986]; tissue remodeling [GO:0048771] basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; sarcoplasmic reticulum [GO:0016529] calcium ion binding [GO:0005509]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178] 0.92383 -1.0269 LLWKDSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.149 0 0 0 0 P35453 HXD13_HUMAN Homeobox protein Hox-D13 (Homeobox protein Hox-4I) HOXD13 HOX4I Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; branch elongation of an epithelium [GO:0060602]; embryonic digit morphogenesis [GO:0042733]; embryonic hindgut morphogenesis [GO:0048619]; male genitalia development [GO:0030539]; morphogenesis of an epithelial fold [GO:0060571]; positive regulation of transcription by RNA polymerase II [GO:0045944]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; regulation of branching involved in prostate gland morphogenesis [GO:0060687]; regulation of cell population proliferation [GO:0042127]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; response to testosterone [GO:0033574]; skeletal system development [GO:0001501]; transcription by RNA polymerase II [GO:0006366] chromatin [GO:0000785]; nucleoplasm [GO:0005654] "chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.91729 -0.87264 ELENEYAINK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2929 0 0 0 0 0 0 0 0 0 0 9.64744 P35475 IDUA_HUMAN Alpha-L-iduronidase (EC 3.2.1.76) IDUA Homo sapiens (Human) dermatan sulfate catabolic process [GO:0030209]; disaccharide metabolic process [GO:0005984]; glycosaminoglycan catabolic process [GO:0006027]; heparan sulfate proteoglycan catabolic process [GO:0030200]; heparin catabolic process [GO:0030211] coated vesicle [GO:0030135]; extracellular exosome [GO:0070062]; lysosomal lumen [GO:0043202] L-iduronidase activity [GO:0003940]; signaling receptor binding [GO:0005102] 0.80539 0.2362 SVAVTLR 0 0 0 0 0 0 9.96924 0 0 0 0 9.51485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P35498 SCN1A_HUMAN Sodium channel protein type 1 subunit alpha (Sodium channel protein brain I subunit alpha) (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) SCN1A NAC1 SCN1 Homo sapiens (Human) adult walking behavior [GO:0007628]; calcium ion import across plasma membrane [GO:0098703]; cardiac muscle cell action potential involved in contraction [GO:0086002]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; establishment of localization in cell [GO:0051649]; neuromuscular process controlling posture [GO:0050884]; neuronal action potential [GO:0019228]; neuronal action potential propagation [GO:0019227]; regulation of monoatomic ion transmembrane transport [GO:0034765]; sodium ion transport [GO:0006814] axon initial segment [GO:0043194]; intercalated disc [GO:0014704]; neuronal cell body [GO:0043025]; node of Ranvier [GO:0033268]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; T-tubule [GO:0030315]; voltage-gated calcium channel complex [GO:0005891]; voltage-gated sodium channel complex [GO:0001518]; Z disc [GO:0030018] high voltage-gated calcium channel activity [GO:0008331]; voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential [GO:0099508]; voltage-gated sodium channel activity [GO:0005248] 0.96915 -4.1793 EPSAAGRLSDSSSEASK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.83905 0 0 0 0 0 0 0 P35499 SCN4A_HUMAN Sodium channel protein type 4 subunit alpha (SkM1) (Sodium channel protein skeletal muscle subunit alpha) (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) SCN4A Homo sapiens (Human) calcium ion import across plasma membrane [GO:0098703]; muscle contraction [GO:0006936]; regulation of monoatomic ion transmembrane transport [GO:0034765]; regulation of skeletal muscle contraction by action potential [GO:0100001]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; voltage-gated sodium channel complex [GO:0001518] high voltage-gated calcium channel activity [GO:0008331]; voltage-gated sodium channel activity [GO:0005248] 0.96384 -2.2041 FDISEVNNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.43673 0 0 0 0 0 0 0 0 0 10.7609 0 0 P35527 K1C9_HUMAN "Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9)" KRT9 Homo sapiens (Human) epidermis development [GO:0008544]; epithelial cell differentiation [GO:0030855]; intermediate filament organization [GO:0045109]; skin development [GO:0043588]; spermatogenesis [GO:0007283] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; keratin filament [GO:0045095]; membrane [GO:0016020]; nucleus [GO:0005634] structural constituent of cytoskeleton [GO:0005200] 0 323.31 DIENQYETQITQIEHEVSSSGQEVQSSAK 14.6585 14.3654 14.5503 9.42007 11.0444 10.4018 14.4624 14.4945 14.5649 15.16 15.1459 15.0632 12.7184 13.0185 13.0706 15.1999 15.3135 15.0721 13.8776 13.6899 14.0094 13.5324 12.5936 12.675 13.9574 14.0901 13.9904 P35555 FBN1_HUMAN Fibrillin-1 [Cleaved into: Asprosin] FBN1 FBN Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; microfibril [GO:0001527] calcium ion binding [GO:0005509]; extracellular matrix constituent conferring elasticity [GO:0030023]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; protein-containing complex binding [GO:0044877] 0.95908 -1.7609 CECPVGFFYNDK 10.2445 9.96924 10.0625 0 0 0 9.71315 9.83403 10.0843 10.2567 9.90034 11.5745 0 0 0 0 0 7.98231 0 0 0 0 0 0 9.63261 0 0 P35556 FBN2_HUMAN Fibrillin-2 [Cleaved into: Placensin] FBN2 Homo sapiens (Human) bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; microfibril [GO:0001527] calcium ion binding [GO:0005509]; extracellular matrix constituent conferring elasticity [GO:0030023]; extracellular matrix structural constituent [GO:0005201]; hormone activity [GO:0005179] 0.96379 -2.1109 KICPHGPGYTTDGR 9.017 0 0 0 0 0 0 0 0 0 0 0 0 10.0393 0 0 0 0 0 0 0 0 0 0 0 0 0 P35568 IRS1_HUMAN Insulin receptor substrate 1 (IRS-1) IRS1 Homo sapiens (Human) cellular response to fatty acid [GO:0071398]; cellular response to insulin stimulus [GO:0032869]; glucose homeostasis [GO:0042593]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of insulin secretion [GO:0046676]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of glucose import [GO:0046326]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; response to insulin [GO:0032868]; response to peptide hormone [GO:0043434]; signal transduction [GO:0007165] caveola [GO:0005901]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; insulin receptor complex [GO:0005899]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] insulin receptor binding [GO:0005158]; insulin-like growth factor receptor binding [GO:0005159]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphotyrosine residue binding [GO:0001784]; protein kinase C binding [GO:0005080]; SH2 domain binding [GO:0042169]; signaling receptor complex adaptor activity [GO:0030159]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068] 0.88755 -0.34217 LSLGDPK 0 0 0 0 0 0 11.9896 0 0 0 0 0 0 0 0 0 0 0 9.34567 0 0 0 0 0 0 0 0 P35573 GDE_HUMAN "Glycogen debranching enzyme (Glycogen debrancher) [Includes: 4-alpha-glucanotransferase (EC 2.4.1.25) (Oligo-1,4-1,4-glucantransferase); Amylo-alpha-1,6-glucosidase (Amylo-1,6-glucosidase) (EC 3.2.1.33) (Dextrin 6-alpha-D-glucosidase)]" AGL GDE Homo sapiens (Human) glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980]; response to glucocorticoid [GO:0051384]; response to nutrient [GO:0007584] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; inclusion body [GO:0016234]; isoamylase complex [GO:0043033]; nucleus [GO:0005634]; sarcoplasmic reticulum [GO:0016529]; secretory granule lumen [GO:0034774] "4-alpha-glucanotransferase activity [GO:0004134]; amylo-alpha-1,6-glucosidase activity [GO:0004135]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; glycogen debranching enzyme activity [GO:0004133]; polysaccharide binding [GO:0030247]; polyubiquitin modification-dependent protein binding [GO:0031593]" 0.8975 -0.53654 ERNAGPQIDRNMK 0 11.0123 0 0 0 0 0 0 0 9.47084 0 0 0 0 0 0 0 0 0 0 10.4613 9.78852 0 0 0 0 0 P35579 MYH9_HUMAN "Myosin-9 (Cellular myosin heavy chain, type A) (Myosin heavy chain 9) (Myosin heavy chain, non-muscle IIa) (Non-muscle myosin heavy chain A) (NMMHC-A) (Non-muscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA)" MYH9 Homo sapiens (Human) "actin cytoskeleton reorganization [GO:0031532]; actin filament-based movement [GO:0030048]; actomyosin structure organization [GO:0031032]; angiogenesis [GO:0001525]; blood vessel endothelial cell migration [GO:0043534]; cortical granule exocytosis [GO:0060471]; cytokinetic process [GO:0032506]; establishment of meiotic spindle localization [GO:0051295]; establishment of T cell polarity [GO:0001768]; in utero embryonic development [GO:0001701]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; lysosome localization [GO:0032418]; meiotic spindle organization [GO:0000212]; membrane protein ectodomain proteolysis [GO:0006509]; monocyte differentiation [GO:0030224]; myoblast fusion [GO:0007520]; negative regulation of actin filament severing [GO:1903919]; phagocytosis, engulfment [GO:0006911]; plasma membrane repair [GO:0001778]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein transport [GO:0015031]; regulated exocytosis [GO:0045055]; regulation of cell shape [GO:0008360]; regulation of plasma membrane repair [GO:1905684]; uropod organization [GO:0032796]" actin cytoskeleton [GO:0015629]; actomyosin [GO:0042641]; actomyosin contractile ring [GO:0005826]; adherens junction [GO:0005912]; brush border [GO:0005903]; cell leading edge [GO:0031252]; cleavage furrow [GO:0032154]; cortical granule [GO:0060473]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; membrane [GO:0016020]; myosin filament [GO:0032982]; myosin II complex [GO:0016460]; myosin II filament [GO:0097513]; neuromuscular junction [GO:0031594]; nuclear body [GO:0016604]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; spindle [GO:0005819]; stress fiber [GO:0001725]; uropod [GO:0001931] actin binding [GO:0003779]; actin filament binding [GO:0051015]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; cytoskeletal motor activity [GO:0003774]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; microfilament motor activity [GO:0000146]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein-membrane adaptor activity [GO:0043495]; RNA binding [GO:0003723] 0 78.468 ALEEAMEQK 10.9759 10.4812 11.0141 0 0 0 12.6589 11.0316 12.7142 10.0972 0 0 0 11.3435 9.9383 11.5553 10.642 11.5933 0 0 0 0 0 0 0 0 0 P35580 MYH10_HUMAN "Myosin-10 (Cellular myosin heavy chain, type B) (Myosin heavy chain 10) (Myosin heavy chain, non-muscle IIb) (Non-muscle myosin heavy chain B) (NMMHC-B) (Non-muscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB)" MYH10 Homo sapiens (Human) actin filament-based movement [GO:0030048]; actomyosin structure organization [GO:0031032]; cell adhesion [GO:0007155]; mitotic cytokinesis [GO:0000281]; positive regulation of protein secretion [GO:0050714]; regulation of cell shape [GO:0008360] actomyosin [GO:0042641]; cell cortex [GO:0005938]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lamellipodium [GO:0030027]; midbody [GO:0030496]; myosin complex [GO:0016459]; myosin filament [GO:0032982]; myosin II complex [GO:0016460]; myosin II filament [GO:0097513]; nucleus [GO:0005634]; polysome [GO:0005844]; stress fiber [GO:0001725] actin binding [GO:0003779]; actin filament binding [GO:0051015]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; microfilament motor activity [GO:0000146]; mRNA 5'-UTR binding [GO:0048027]; RNA stem-loop binding [GO:0035613] 0.96734 -2.8252 ALELDPNLYR 0 0 0 0 0 0 0 0 0 0 11.6685 0 0 0 0 10.0833 0 0 0 0 0 0 0 0 0 0 9.76896 P35590 TIE1_HUMAN Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1) TIE1 TIE Homo sapiens (Human) angiogenesis [GO:0001525]; aortic valve morphogenesis [GO:0003180]; branching involved in lymph vessel morphogenesis [GO:0060854]; in utero embryonic development [GO:0001701]; lymphatic endothelial cell differentiation [GO:0060836]; mesoderm development [GO:0007498]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell migration [GO:0030336]; plasma membrane fusion [GO:0045026]; positive regulation of kinase activity [GO:0033674]; protein phosphorylation [GO:0006468]; regulation of endothelial cell proliferation [GO:0001936]; regulation of extracellular matrix assembly [GO:1901201]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]; tissue remodeling [GO:0048771]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570] plasma membrane [GO:0005886]; receptor complex [GO:0043235] ATP binding [GO:0005524]; transmembrane receptor protein tyrosine kinase activity [GO:0004714] 0.91881 -0.88919 VLETDPAFAREHGTASTLSSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1657 0 0 P35606 COPB2_HUMAN Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102) COPB2 Homo sapiens (Human) "endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; toxin transport [GO:1901998]" COPI vesicle coat [GO:0030126]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; transport vesicle [GO:0030133] structural molecule activity [GO:0005198] 0.05074 1.4232 DFSMADKVLPTIPK 10.2075 0 0 0 0 0 9.21079 0 0 0 10.6376 0 0 0 0 0 9.23419 0 11.0535 0 9.70157 9.33735 0 9.44615 11.8579 10.7216 10.3686 P35611 ADDA_HUMAN Alpha-adducin (Erythrocyte adducin subunit alpha) ADD1 ADDA Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; barbed-end actin filament capping [GO:0051016]; cellular response to calcium ion [GO:0071277]; positive regulation of adherens junction organization [GO:1903393]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of protein binding [GO:0032092] adherens junction [GO:0005912]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; F-actin capping protein complex [GO:0008290]; focal adhesion [GO:0005925]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] actin binding [GO:0003779]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; spectrin binding [GO:0030507] 0.93305 -1.2843 HSFQKQQREK 0 0 0 0 0 0 0 0 0 10.0403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P35612 ADDB_HUMAN Beta-adducin (Erythrocyte adducin subunit beta) ADD2 ADDB Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; barbed-end actin filament capping [GO:0051016]; hemopoiesis [GO:0030097]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; positive regulation of protein binding [GO:0032092]; protein-containing complex assembly [GO:0065003]; synapse assembly [GO:0007416] cytoplasmic vesicle [GO:0031410]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; F-actin capping protein complex [GO:0008290]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; postsynaptic density [GO:0014069] actin binding [GO:0003779]; actin filament binding [GO:0051015]; calmodulin binding [GO:0005516]; molecular adaptor activity [GO:0060090]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200] 0.9628 -2.1555 GERLMRCK 9.50861 0 0 0 0 0 0 0 0 0 0 11.568 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P35613 BASI_HUMAN Basigin (5F7) (Collagenase stimulatory factor) (Extracellular matrix metalloproteinase inducer) (EMMPRIN) (Hepatoma-associated antigen) (HAb18G) (Leukocyte activation antigen M6) (OK blood group antigen) (Tumor cell-derived collagenase stimulatory factor) (TCSF) (CD antigen CD147) BSG UNQ6505/PRO21383 Homo sapiens (Human) angiogenesis [GO:0001525]; cell surface receptor signaling pathway [GO:0007166]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; endothelial tube morphogenesis [GO:0061154]; neural retina development [GO:0003407]; neutrophil chemotaxis [GO:0030593]; odontogenesis of dentin-containing tooth [GO:0042475]; photoreceptor cell maintenance [GO:0045494]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of matrix metallopeptidase secretion [GO:1904466]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of viral entry into host cell [GO:0046598]; protein localization to plasma membrane [GO:0072659]; response to cAMP [GO:0051591]; response to mercury ion [GO:0046689]; response to peptide hormone [GO:0043434] acrosomal membrane [GO:0002080]; basolateral plasma membrane [GO:0016323]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383] cadherin binding [GO:0045296]; mannose binding [GO:0005537]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618] 0.50824 0.60822 FFVSSSQGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4018 0 P35637 FUS_HUMAN RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein) FUS TLS Homo sapiens (Human) amyloid fibril formation [GO:1990000]; mRNA stabilization [GO:0048255]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein homooligomerization [GO:0051260]; regulation of DNA-templated transcription [GO:0006355]; regulation of RNA splicing [GO:0043484]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA splicing [GO:0008380] cytoplasm [GO:0005737]; intracellular non-membrane-bounded organelle [GO:0043232]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molecular condensate scaffold activity [GO:0140693]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712] 0.96942 -4.6553 AAIDWFDGKEFSGNPIK 9.34944 0 0 0 0 0 0 0 0 9.09461 8.62048 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7959 9.59434 0 P35658 NU214_HUMAN Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN) NUP214 CAIN CAN KIAA0023 Homo sapiens (Human) mitotic cell cycle [GO:0000278]; mRNA export from nucleus [GO:0006406]; nucleocytoplasmic transport [GO:0006913]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; regulation of cell cycle [GO:0051726]; regulation of nucleocytoplasmic transport [GO:0046822]; RNA export from nucleus [GO:0006405] cytoplasmic side of nuclear pore [GO:1990876]; cytosol [GO:0005829]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654] nuclear export signal receptor activity [GO:0005049]; nuclear localization sequence binding [GO:0008139]; structural constituent of nuclear pore [GO:0017056] 0.96426 -2.2723 IFDSPEELPKERSSLLAVSNK 0 9.32679 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9125 0 0 P35659 DEK_HUMAN Protein DEK DEK Homo sapiens (Human) chromatin remodeling [GO:0006338]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; regulation of double-strand break repair [GO:2000779]; regulation of double-strand break repair via nonhomologous end joining [GO:2001032]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transcription by RNA polymerase II [GO:0006366]; viral genome replication [GO:0019079] B-WICH complex [GO:0110016]; contractile fiber [GO:0043292]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; histone binding [GO:0042393]; RNA binding [GO:0003723] 0.96956 -5.4715 ADSSTTK 0 0 0 0 0 0 0 11.1311 0 0 7.84229 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.98988 9.2411 P35663 CYLC1_HUMAN Cylicin-1 (Cylicin I) (Multiple-band polypeptide I) CYLC1 CYL CYL1 Homo sapiens (Human) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] acrosomal matrix [GO:0043159]; cytoskeletal calyx [GO:0033150]; nucleus [GO:0005634] structural constituent of cytoskeleton [GO:0005200]; structural molecule activity [GO:0005198] 0.84164 0.1457 TYDNSIPISESSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0867 0 0 0 0 0 0 10.3264 8.98698 9.42341 P35711 SOX5_HUMAN Transcription factor SOX-5 SOX5 Homo sapiens (Human) asymmetric neuroblast division [GO:0055059]; cartilage condensation [GO:0001502]; cartilage development [GO:0051216]; cell fate commitment [GO:0045165]; cellular response to transforming growth factor beta stimulus [GO:0071560]; chondrocyte differentiation [GO:0002062]; positive regulation of cartilage development [GO:0061036]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of mesenchymal stem cell differentiation [GO:2000741]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; transcription cis-regulatory region binding [GO:0000976]" 0.95961 -1.8508 LAASQIEKQRQQMELAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.34494 0 P35749 MYH11_HUMAN "Myosin-11 (Myosin heavy chain 11) (Myosin heavy chain, smooth muscle isoform) (SMMHC)" MYH11 KIAA0866 Homo sapiens (Human) actomyosin structure organization [GO:0031032]; cardiac muscle cell development [GO:0055013]; elastic fiber assembly [GO:0048251]; skeletal muscle myosin thick filament assembly [GO:0030241]; smooth muscle contraction [GO:0006939] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; melanosome [GO:0042470]; muscle myosin complex [GO:0005859]; myosin filament [GO:0032982]; myosin II complex [GO:0016460] actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; microfilament motor activity [GO:0000146]; structural constituent of muscle [GO:0008307] 0.92386 -1.0692 ALELDPNLYR 9.27415 0 0 0 0 0 0 0 0 0 0 16.2326 0 0 0 10.4044 0 9.04472 0 0 10.4016 11.8458 0 0 0 0 0 P35789 ZNF93_HUMAN Zinc finger protein 93 (Zinc finger protein 505) (Zinc finger protein HTF34) ZNF93 ZNF505 Homo sapiens (Human) retrotransposon silencing [GO:0010526] nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; zinc ion binding [GO:0008270]" 0.96271 -2.0938 AFIASSTLSRHEFIHMGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1787 0 P35790 CHKA_HUMAN Choline kinase alpha (CK) (EC 2.7.1.32) (CHETK-alpha) (Ethanolamine kinase) (EK) (EC 2.7.1.82) CHKA CHK CKI Homo sapiens (Human) CDP-choline pathway [GO:0006657]; cellular response to glucose starvation [GO:0042149]; lipid droplet disassembly [GO:1905691]; lipid metabolic process [GO:0006629]; lipid transport [GO:0006869]; phosphatidylcholine biosynthetic process [GO:0006656]; phosphatidylethanolamine biosynthetic process [GO:0006646]; phosphorylation [GO:0016310] cytoplasm [GO:0005737]; cytosol [GO:0005829]; lipid droplet [GO:0005811] ATP binding [GO:0005524]; choline kinase activity [GO:0004103]; cholinesterase activity [GO:0004104]; ethanolamine kinase activity [GO:0004305]; kinase activator activity [GO:0019209]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activator activity [GO:0030296]; protein tyrosine kinase activity [GO:0004713] 0.9628 -2.4457 EFLPGAWRGLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9447 P35813 PPM1A_HUMAN Protein phosphatase 1A (EC 3.1.3.16) (Protein phosphatase 2C isoform alpha) (PP2C-alpha) (Protein phosphatase IA) PPM1A PPPM1A Homo sapiens (Human) cellular response to transforming growth factor beta stimulus [GO:0071560]; dephosphorylation [GO:0016311]; N-terminal protein myristoylation [GO:0006499]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of SMAD protein complex assembly [GO:0010991]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein export from nucleus [GO:0046827]; protein dephosphorylation [GO:0006470]; protein export from nucleus [GO:0006611]; regulation of cell cycle [GO:0051726] cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] calmodulin-dependent protein phosphatase activity [GO:0033192]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; myosin phosphatase activity [GO:0017018]; protein serine/threonine phosphatase activity [GO:0004722]; R-SMAD binding [GO:0070412] 0.54579 0.57089 DNMSVILICFPNAPK 0 0 0 0 0 0 0 11.8955 12.0166 12.3271 12.3035 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6155 0 0 P35858 ALS_HUMAN Insulin-like growth factor-binding protein complex acid labile subunit (ALS) IGFALS ALS Homo sapiens (Human) cell adhesion [GO:0007155]; signal transduction [GO:0007165] extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; insulin-like growth factor ternary complex [GO:0042567] insulin-like growth factor binding [GO:0005520] 0.88352 -0.045432 SFEGLGQLEVLTLDHNQLQEVK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.68806 0 0 0 0 0 0 0 0 0 0 0 0 0 P35900 K1C20_HUMAN "Keratin, type I cytoskeletal 20 (Cytokeratin-20) (CK-20) (Keratin-20) (K20) (Protein IT)" KRT20 Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to starvation [GO:0009267]; epithelial cell differentiation [GO:0030855]; intermediate filament organization [GO:0045109]; regulation of protein secretion [GO:0050708] cytoplasm [GO:0005737]; cytosol [GO:0005829]; intermediate filament [GO:0005882]; intermediate filament cytoskeleton [GO:0045111] structural constituent of cytoskeleton [GO:0005200] 0.78251 0.2529 LEQEIATYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.93621 0 0 0 0 P35908 K22E_HUMAN "Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (CK-2e) (Epithelial keratin-2e) (Keratin-2 epidermis) (Keratin-2e) (K2e) (Type-II keratin Kb2)" KRT2 KRT2A KRT2E Homo sapiens (Human) epidermis development [GO:0008544]; intermediate filament organization [GO:0045109]; keratinization [GO:0031424]; keratinocyte activation [GO:0032980]; keratinocyte development [GO:0003334]; keratinocyte migration [GO:0051546]; keratinocyte proliferation [GO:0043616]; peptide cross-linking [GO:0018149]; positive regulation of epidermis development [GO:0045684] cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intermediate filament [GO:0005882]; keratin filament [GO:0045095]; membrane [GO:0016020]; nucleus [GO:0005634] cytoskeletal protein binding [GO:0008092]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of skin epidermis [GO:0030280] 0 159.63 AQYEEIAQR 12.9634 13.3659 12.7687 10.1403 10.6445 10.4974 13.5993 13.634 13.7669 14.0552 13.4081 13.6755 11.8164 12.5725 12.4856 14.0729 14.004 13.1166 11.6715 12.7251 12.5356 12.3036 11.9252 12.0681 12.5557 13.1794 12.3705 P35913 PDE6B_HUMAN "Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta (GMP-PDE beta) (EC 3.1.4.35)" PDE6B PDEB Homo sapiens (Human) "entrainment of circadian clock by photoperiod [GO:0043153]; phototransduction, visible light [GO:0007603]; retina development in camera-type eye [GO:0060041]; retinal cell apoptotic process [GO:1990009]; visual perception [GO:0007601]" photoreceptor disc membrane [GO:0097381]; photoreceptor outer segment membrane [GO:0042622]; plasma membrane [GO:0005886] "3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; metal ion binding [GO:0046872]" 0.92136 -0.93571 ITYHNWR 0 0 0 0 0 0 0 0 0 0 0 0 8.77456 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P35914 HMGCL_HUMAN "Hydroxymethylglutaryl-CoA lyase, mitochondrial (HL) (HMG-CoA lyase) (EC 4.1.3.4) (3-hydroxy-3-methylglutarate-CoA lyase)" HMGCL Homo sapiens (Human) ketone body biosynthetic process [GO:0046951]; leucine catabolic process [GO:0006552]; lipid metabolic process [GO:0006629]; mitochondrion organization [GO:0007005] cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991] hydroxymethylglutaryl-CoA lyase activity [GO:0004419]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198] 0.95617 -1.5928 KNINCSIEESFQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.1529 0 0 0 0 0 P35916 VGFR3_HUMAN Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4) FLT4 VEGFR3 Homo sapiens (Human) angiogenesis [GO:0001525]; blood vessel morphogenesis [GO:0048514]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; lung alveolus development [GO:0048286]; lymph vessel development [GO:0001945]; lymphangiogenesis [GO:0001946]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of JNK cascade [GO:0046330]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor production [GO:0010575]; protein autophosphorylation [GO:0046777]; regulation of blood vessel remodeling [GO:0060312]; regulation of MAPK cascade [GO:0043408]; respiratory system process [GO:0003016]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculature development [GO:0001944] cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] ATP binding [GO:0005524]; growth factor binding [GO:0019838]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor receptor activity [GO:0005021] 0.96906 -3.3778 EEDAGRYLCSVCNAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5867 0 0 0 0 0 0 0 0 0 0 0 0 P35968 VGFR2_HUMAN Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309) KDR FLK1 VEGFR2 Homo sapiens (Human) angiogenesis [GO:0001525]; blood vessel endothelial cell differentiation [GO:0060837]; branching involved in blood vessel morphogenesis [GO:0001569]; calcium ion homeostasis [GO:0055074]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell fate commitment [GO:0045165]; cell migration [GO:0016477]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hydrogen sulfide [GO:1904881]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic hemopoiesis [GO:0035162]; endocardium development [GO:0003157]; endothelial cell differentiation [GO:0045446]; endothelium development [GO:0003158]; epithelial cell maturation [GO:0002070]; epithelial cell proliferation [GO:0050673]; ERK1 and ERK2 cascade [GO:0070371]; lung alveolus development [GO:0048286]; lymph vessel development [GO:0001945]; mesenchymal cell proliferation [GO:0010463]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron apoptotic process [GO:0043524]; ovarian follicle development [GO:0001541]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of kinase activity [GO:0033674]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of vasculogenesis [GO:2001214]; post-embryonic camera-type eye morphogenesis [GO:0048597]; protein autophosphorylation [GO:0046777]; protein kinase B signaling [GO:0043491]; regulation of bone development [GO:1903010]; regulation of cell shape [GO:0008360]; regulation of hematopoietic progenitor cell differentiation [GO:1901532]; regulation of MAPK cascade [GO:0043408]; semaphorin-plexin signaling pathway [GO:0071526]; stem cell proliferation [GO:0072089]; surfactant homeostasis [GO:0043129]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324]; vascular endothelial growth factor signaling pathway [GO:0038084]; vascular wound healing [GO:0061042]; vasculogenesis [GO:0001570] anchoring junction [GO:0070161]; cell junction [GO:0030054]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; membrane raft [GO:0045121]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; sorting endosome [GO:0097443] ATP binding [GO:0005524]; cadherin binding [GO:0045296]; coreceptor activity [GO:0015026]; growth factor binding [GO:0019838]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor receptor activity [GO:0005021] 0.88764 -0.35287 TELNVGIDFNWEYPSSKHQHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3572 0 0 0 0 P35998 PRS7_HUMAN 26S proteasome regulatory subunit 7 (26S proteasome AAA-ATPase subunit RPT1) (Proteasome 26S subunit ATPase 2) PSMC2 MSS1 Homo sapiens (Human) osteoblast differentiation [GO:0001649]; positive regulation of proteasomal protein catabolic process [GO:1901800]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; ubiquitin-dependent protein catabolic process [GO:0006511] "cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; proteasome accessory complex [GO:0022624]; proteasome complex [GO:0000502]; proteasome regulatory particle, base subcomplex [GO:0008540]; secretory granule lumen [GO:0034774]" ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; proteasome-activating activity [GO:0036402] 0.11679 1.1082 ALDEGDIALLK 0 0 0 0 0 0 0 0 0 0 0 0 11.1916 0 11.634 0 0 0 0 0 9.93204 0 0 0 0 0 0 P36269 GGT5_HUMAN Glutathione hydrolase 5 proenzyme (EC 3.4.19.13) (Gamma-glutamyl transpeptidase-related enzyme) (GGT-rel) (Gamma-glutamyltransferase 5) (GGT 5) (EC 2.3.2.2) (Gamma-glutamyltransferase-like activity 1) (Gamma-glutamyltranspeptidase 5) (Leukotriene-C4 hydrolase) (EC 3.4.19.14) [Cleaved into: Glutathione hydrolase 5 heavy chain; Glutathione hydrolase 5 light chain] GGT5 GGTLA1 Homo sapiens (Human) amino acid metabolic process [GO:0006520]; fatty acid metabolic process [GO:0006631]; glutathione biosynthetic process [GO:0006750]; glutathione catabolic process [GO:0006751]; inflammatory response [GO:0006954]; leukotriene D4 biosynthetic process [GO:1901750]; proteolysis [GO:0006508] plasma membrane [GO:0005886] glutathione hydrolase activity [GO:0036374]; hypoglycin A gamma-glutamyl transpeptidase activity [GO:0102953]; leukotriene C4 gamma-glutamyl transferase activity [GO:0103068]; leukotriene-C(4) hydrolase [GO:0002951]; peptidyltransferase activity [GO:0000048] 0.63151 0.39921 VGGAPGR 9.2054 9.43003 8.95489 9.40109 14.4689 14.4878 9.34868 0 0 15.7972 0 0 11.0293 14.6148 0 0 0 10.105 10.5063 10.6067 10.397 9.73721 10.3236 10.6093 9.73479 10.7695 0 P36383 CXG1_HUMAN Gap junction gamma-1 protein (Connexin-45) (Cx45) (Gap junction alpha-7 protein) GJC1 GJA7 Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; AV node cell to bundle of His cell communication by electrical coupling [GO:0086053]; cardiac muscle tissue development [GO:0048738]; cell development [GO:0048468]; cell-cell junction assembly [GO:0007043]; cell-cell signaling [GO:0007267]; chemical synaptic transmission [GO:0007268]; gap junction assembly [GO:0016264]; muscle contraction [GO:0006936]; SA node cell to atrial cardiac muscle cell communication by electrical coupling [GO:0086021]; vasculogenesis [GO:0001570]; visual perception [GO:0007601] connexin complex [GO:0005922]; endoplasmic reticulum membrane [GO:0005789]; gap junction [GO:0005921]; intercalated disc [GO:0014704]; plasma membrane [GO:0005886]; synapse [GO:0045202] gap junction channel activity [GO:0005243]; gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling [GO:0086077]; gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling [GO:0086020]; monoatomic ion channel activity [GO:0005216] 0.96722 -2.3301 IAYKQNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.03144 0 8.85125 0 9.74819 0 P36402 TCF7_HUMAN Transcription factor 7 (TCF-7) (T-cell-specific transcription factor 1) (T-cell factor 1) (TCF-1) TCF7 TCF1 Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; cellular response to interleukin-4 [GO:0071353]; gamma-delta T cell differentiation [GO:0042492]; immune response [GO:0006955]; regulation of DNA-templated transcription [GO:0006355]; regulation of gamma-delta T cell differentiation [GO:0045586]; regulation of transcription by RNA polymerase II [GO:0006357] beta-catenin-TCF complex [GO:1990907]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "beta-catenin binding [GO:0008013]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity [GO:0001217]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]" 0.86328 0.08372 VIAECTLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.72782 P36508 ZNF76_HUMAN Zinc finger protein 76 (Zinc finger protein 523) ZNF76 D6S229E ZNF523 Homo sapiens (Human) central nervous system development [GO:0007417]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription by RNA polymerase III [GO:0006359] nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.75927 0.30186 LYTTAHHLK 9.80816 0 0 0 0 0 0 0 0 0 9.81586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P36542 ATPG_HUMAN "ATP synthase subunit gamma, mitochondrial (ATP synthase F1 subunit gamma) (F-ATPase gamma subunit)" ATP5F1C ATP5C ATP5C1 ATP5CL1 Homo sapiens (Human) ATP biosynthetic process [GO:0006754]; oxidative phosphorylation [GO:0006119]; proton motive force-driven ATP synthesis [GO:0015986]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776] "membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial proton-transporting ATP synthase complex [GO:0005753]; mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1) [GO:0000275]; mitochondrion [GO:0005739]" "proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; RNA binding [GO:0003723]" 0.030905 1.5316 IYGLGSLALYEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.44944 9.47812 9.33764 0 0 0 P36578 RL4_HUMAN Large ribosomal subunit protein uL4 (60S ribosomal protein L1) (60S ribosomal protein L4) RPL4 RPL1 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; rough endoplasmic reticulum [GO:0005791] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0 4.4768 AAAAAAALQAK 8.6189 8.70297 0 0 0 0 10.7788 10.3444 10.7816 9.15256 8.95466 9.04652 9.1756 9.182 9.19631 11.8055 9.51562 10.8353 9.84721 10.2029 9.34822 9.70394 10.3826 11.5525 12.3308 12.4848 12.0253 P36776 LONM_HUMAN "Lon protease homolog, mitochondrial (EC 3.4.21.53) (LONHs) (Lon protease-like protein) (LONP) (Mitochondrial ATP-dependent protease Lon) (Serine protease 15)" LONP1 PRSS15 Homo sapiens (Human) aging [GO:0007568]; cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein complex assembly [GO:0051131]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial genome maintenance [GO:0000002]; mitochondrion organization [GO:0007005]; negative regulation of insulin receptor signaling pathway [GO:0046627]; oxidation-dependent protein catabolic process [GO:0070407]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; response to aluminum ion [GO:0010044]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666] cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent peptidase activity [GO:0004176]; DNA polymerase binding [GO:0070182]; G-quadruplex DNA binding [GO:0051880]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; mitochondrial promoter sequence-specific DNA binding [GO:0001018]; PH domain binding [GO:0042731]; sequence-specific DNA binding [GO:0043565]; serine-type endopeptidase activity [GO:0004252]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727] 0.96986 -4.3544 ALCGLDESKAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.598 0 0 0 0 0 0 0 0 0 12.647 0 0 P36871 PGM1_HUMAN Phosphoglucomutase-1 (PGM 1) (EC 5.4.2.2) (Glucose phosphomutase 1) PGM1 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; gluconeogenesis [GO:0006094]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724] magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614] 0.0057803 2.3352 DLEALMFDR 0 0 0 0 0 10.668 0 0 0 0 0 0 0 9.44253 0 10.9044 0 0 0 0 0 0 0 0 0 0 0 P36888 FLT3_HUMAN Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135) FLT3 CD135 FLK2 STK1 Homo sapiens (Human) animal organ regeneration [GO:0031100]; B cell differentiation [GO:0030183]; cellular response to cytokine stimulus [GO:0071345]; cellular response to glucocorticoid stimulus [GO:0071385]; common myeloid progenitor cell proliferation [GO:0035726]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; hemopoiesis [GO:0030097]; leukocyte homeostasis [GO:0001776]; lymphocyte proliferation [GO:0046651]; myeloid progenitor cell differentiation [GO:0002318]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; pro-B cell differentiation [GO:0002328]; protein autophosphorylation [GO:0046777]; regulation of apoptotic process [GO:0042981]; response to organonitrogen compound [GO:0010243]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] ATP binding [GO:0005524]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; nuclear glucocorticoid receptor binding [GO:0035259]; protein self-association [GO:0043621]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor receptor activity [GO:0005021] 0.56186 0.52876 EALMSELK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.6393 0 0 0 9.2755 0 0 0 0 0 0 0 0 0 P36915 GNL1_HUMAN Guanine nucleotide-binding protein-like 1 (GTP-binding protein HSR1) GNL1 HSR1 Homo sapiens (Human) DNA damage response [GO:0006974]; signal transduction [GO:0007165]; T cell mediated immunity [GO:0002456] extracellular space [GO:0005615]; nucleus [GO:0005634] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; structural molecule activity [GO:0005198] 0.96179 -2.075 ACEAITVGK 0 0 10.0992 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7357 0 0 P36952 SPB5_HUMAN Serpin B5 (Maspin) (Peptidase inhibitor 5) (PI-5) SERPINB5 PI5 Homo sapiens (Human) extracellular matrix organization [GO:0030198]; morphogenesis of an epithelium [GO:0002009]; negative regulation of endopeptidase activity [GO:0010951]; prostate gland morphogenesis [GO:0060512]; regulation of epithelial cell proliferation [GO:0050678] cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528] serine-type endopeptidase inhibitor activity [GO:0004867] 0.95735 -1.6592 ECPFRVNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0258 0 0 0 0 P36955 PEDF_HUMAN Pigment epithelium-derived factor (PEDF) (Cell proliferation-inducing gene 35 protein) (EPC-1) (Serpin F1) SERPINF1 PEDF PIG35 Homo sapiens (Human) aging [GO:0007568]; cellular response to cobalt ion [GO:0071279]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to retinoic acid [GO:0071300]; epithelial cell proliferation involved in prostate gland development [GO:0060767]; kidney development [GO:0001822]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of epithelial cell proliferation involved in prostate gland development [GO:0060770]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron death [GO:1901215]; ovulation cycle [GO:0042698]; positive regulation of neurogenesis [GO:0050769]; positive regulation of neuron projection development [GO:0010976]; response to acidic pH [GO:0010447]; response to arsenic-containing substance [GO:0046685]; response to peptide [GO:1901652]; retina development in camera-type eye [GO:0060041]; short-term memory [GO:0007614] axon hillock [GO:0043203]; basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; melanosome [GO:0042470]; perinuclear region of cytoplasm [GO:0048471] serine-type endopeptidase inhibitor activity [GO:0004867] 0.72534 0.35434 LSYEGEVTK 0 0 0 0 0 0 0 0 0 0 9.46199 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P36956 SRBP1_HUMAN Sterol regulatory element-binding protein 1 (SREBP-1) (Class D basic helix-loop-helix protein 1) (bHLHd1) (Sterol regulatory element-binding transcription factor 1) [Cleaved into: Processed sterol regulatory element-binding protein 1 (Transcription factor SREBF1)] SREBF1 BHLHD1 SREBP1 Homo sapiens (Human) aging [GO:0007568]; cellular response to fatty acid [GO:0071398]; cellular response to starvation [GO:0009267]; cholesterol biosynthetic process [GO:0006695]; circadian rhythm [GO:0007623]; fat cell differentiation [GO:0045444]; insulin receptor signaling pathway [GO:0008286]; insulin secretion [GO:0030073]; lipid biosynthetic process [GO:0008610]; lipid localization [GO:0010876]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of insulin secretion [GO:0046676]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of triglyceride metabolic process [GO:0090209]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of fatty acid metabolic process [GO:0019217]; regulation of heart rate by chemical signal [GO:0003062]; regulation of lipid storage [GO:0010883]; regulation of protein stability [GO:0031647]; regulation of protein targeting to mitochondrion [GO:1903214]; regulation of transcription by RNA polymerase II [GO:0006357]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to food [GO:0032094]; response to glucagon [GO:0033762]; response to glucose [GO:0009749]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; response to xenobiotic stimulus [GO:0009410]; SREBP signaling pathway [GO:0032933] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] "chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; nuclear receptor activity [GO:0004879]; protein dimerization activity [GO:0046983]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]; sterol response element binding [GO:0032810]; transcription coregulator binding [GO:0001221]" 0.95405 -1.5167 LKQENLSLR 0 0 0 0 0 0 8.62253 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P36957 ODO2_HUMAN "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2) (OGDC-E2) (Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex) (E2K)" DLST DLTS Homo sapiens (Human) 2-oxoglutarate metabolic process [GO:0006103]; generation of precursor metabolites and energy [GO:0006091]; histone succinylation [GO:0106077]; L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099] cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; oxoglutarate dehydrogenase complex [GO:0045252] acyltransferase activity [GO:0016746]; dihydrolipoyllysine-residue succinyltransferase activity [GO:0004149] 0.80925 0.23204 LGFMSAFVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.66653 0 P36969 GPX4_HUMAN Phospholipid hydroperoxide glutathione peroxidase (PHGPx) (EC 1.11.1.12) (Glutathione peroxidase 4) (GPx-4) (GSHPx-4) GPX4 Homo sapiens (Human) aging [GO:0007568]; arachidonic acid metabolic process [GO:0019369]; chromatin organization [GO:0006325]; glutathione metabolic process [GO:0006749]; lipoxygenase pathway [GO:0019372]; long-chain fatty acid biosynthetic process [GO:0042759]; negative regulation of ferroptosis [GO:0110076]; phospholipid metabolic process [GO:0006644]; protein polymerization [GO:0051258]; regulation of inflammatory response [GO:0050727]; response to estradiol [GO:0032355]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] glutathione peroxidase activity [GO:0004602]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; phospholipid-hydroperoxide glutathione peroxidase activity [GO:0047066]; selenium binding [GO:0008430] 0.84909 0.16515 TEVNYTQLVDLHAR 0 11.231 11.0968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.25817 0 0 P37108 SRP14_HUMAN Signal recognition particle 14 kDa protein (SRP14) (18 kDa Alu RNA-binding protein) SRP14 Homo sapiens (Human) cotranslational protein targeting to membrane [GO:0006613]; protein targeting to ER [GO:0045047]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614] "cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; signal recognition particle, endoplasmic reticulum targeting [GO:0005786]" 7S RNA binding [GO:0008312]; endoplasmic reticulum signal peptide binding [GO:0030942]; RNA binding [GO:0003723] 0 30.243 AAAAAAAAAPAAAATAPTTAATTAATAAQ 0 0 0 0 0 0 0 9.54697 0 0 0 0 0 0 0 0 0 0 10.014 9.51001 9.5131 10.0728 10.1538 10.1823 10.2373 11.022 9.14761 P37173 TGFR2_HUMAN TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) (Transforming growth factor-beta receptor type II) (TGF-beta receptor type II) (TbetaR-II) TGFBR2 Homo sapiens (Human) "activation of protein kinase activity [GO:0032147]; aging [GO:0007568]; animal organ regeneration [GO:0031100]; aorta morphogenesis [GO:0035909]; aortic valve morphogenesis [GO:0003180]; apoptotic process [GO:0006915]; artery morphogenesis [GO:0048844]; atrioventricular valve morphogenesis [GO:0003181]; blood vessel development [GO:0001568]; brain development [GO:0007420]; branching involved in blood vessel morphogenesis [GO:0001569]; bronchus morphogenesis [GO:0060434]; cardiac left ventricle morphogenesis [GO:0003214]; cellular response to growth factor stimulus [GO:0071363]; common-partner SMAD protein phosphorylation [GO:0007182]; digestive tract development [GO:0048565]; embryo implantation [GO:0007566]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic hemopoiesis [GO:0035162]; endocardial cushion fusion [GO:0003274]; gastrulation [GO:0007369]; growth plate cartilage chondrocyte growth [GO:0003430]; heart development [GO:0007507]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; inferior endocardial cushion morphogenesis [GO:1905317]; Langerhans cell differentiation [GO:0061520]; lens development in camera-type eye [GO:0002088]; lens fiber cell apoptotic process [GO:1990086]; lung lobe morphogenesis [GO:0060463]; mammary gland morphogenesis [GO:0060443]; membranous septum morphogenesis [GO:0003149]; miRNA transport [GO:1990428]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; Notch signaling pathway [GO:0007219]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell tolerance induction [GO:0002663]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation [GO:1905007]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of NK T cell differentiation [GO:0051138]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of skeletal muscle tissue regeneration [GO:0043415]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell tolerance induction [GO:0002666]; positive regulation of tolerance induction to self antigen [GO:0002651]; protein phosphorylation [GO:0006468]; receptor-mediated endocytosis [GO:0006898]; regulation of cell population proliferation [GO:0042127]; regulation of gene expression [GO:0010468]; regulation of stem cell proliferation [GO:0072091]; response to cholesterol [GO:0070723]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to nutrient [GO:0007584]; response to steroid hormone [GO:0048545]; response to xenobiotic stimulus [GO:0009410]; roof of mouth development [GO:0060021]; secondary palate development [GO:0062009]; smoothened signaling pathway [GO:0007224]; trachea formation [GO:0060440]; transforming growth factor beta receptor signaling pathway [GO:0007179]; tricuspid valve morphogenesis [GO:0003186]; vasculogenesis [GO:0001570]; ventricular septum morphogenesis [GO:0060412]; wound healing [GO:0042060]" caveola [GO:0005901]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; transforming growth factor beta ligand-receptor complex [GO:0070021] "activin receptor activity [GO:0017002]; ATP binding [GO:0005524]; glycosaminoglycan binding [GO:0005539]; metal ion binding [GO:0046872]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; molecular adaptor activity [GO:0060090]; SMAD binding [GO:0046332]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor activity [GO:0005024]; transforming growth factor beta receptor activity, type II [GO:0005026]; transmembrane receptor protein serine/threonine kinase activity [GO:0004675]; type I transforming growth factor beta receptor binding [GO:0034713]; type III transforming growth factor beta receptor binding [GO:0034714]" 0.88858 -0.43075 FPQLCKFCDVR 9.29694 0 9.10255 0 0 8.95204 0 0 0 0 0 0 0 9.77274 0 0 0 0 9.58233 0 0 0 0 0 0 0 0 P37268 FDFT_HUMAN Squalene synthase (SQS) (SS) (EC 2.5.1.21) (FPP:FPP farnesyltransferase) (Farnesyl-diphosphate farnesyltransferase) (Farnesyl-diphosphate farnesyltransferase 1) FDFT1 Homo sapiens (Human) cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate metabolic process [GO:0045338]; steroid biosynthetic process [GO:0006694] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996] 0.69518 0.37692 DYLEDQQGGR 0 0 0 9.61478 0 9.58474 0 0 0 10.4854 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5226 0 0 P37288 V1AR_HUMAN Vasopressin V1a receptor (V1aR) (AVPR V1a) (Antidiuretic hormone receptor 1a) (Vascular/hepatic-type arginine vasopressin receptor) AVPR1A AVPR1 Homo sapiens (Human) activation of phospholipase C activity [GO:0007202]; blood circulation [GO:0008015]; calcium-mediated signaling [GO:0019722]; cellular response to hormone stimulus [GO:0032870]; cellular response to water deprivation [GO:0042631]; G protein-coupled receptor signaling pathway [GO:0007186]; generation of precursor metabolites and energy [GO:0006091]; grooming behavior [GO:0007625]; maternal aggressive behavior [GO:0002125]; maternal behavior [GO:0042711]; myotube differentiation [GO:0014902]; negative regulation of female receptivity [GO:0007621]; negative regulation of transmission of nerve impulse [GO:0051970]; penile erection [GO:0043084]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of heart rate [GO:0010460]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of systemic arterial blood pressure [GO:0003084]; positive regulation of vasoconstriction [GO:0045907]; regulation of systemic arterial blood pressure by vasopressin [GO:0001992]; response to corticosterone [GO:0051412]; social behavior [GO:0035176]; sperm ejaculation [GO:0042713]; telencephalon development [GO:0021537]; transport across blood-brain barrier [GO:0150104] endocytic vesicle [GO:0030139]; endosome [GO:0005768]; plasma membrane [GO:0005886] peptide binding [GO:0042277]; peptide hormone binding [GO:0017046]; protein kinase C binding [GO:0005080]; V1A vasopressin receptor binding [GO:0031894]; vasopressin receptor activity [GO:0005000] 0.9321 -1.2667 TLQQPARRSR 0 0 0 0 0 8.72253 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P37802 TAGL2_HUMAN Transgelin-2 (Epididymis tissue protein Li 7e) (SM22-alpha homolog) TAGLN2 KIAA0120 CDABP0035 Homo sapiens (Human) actin filament organization [GO:0007015]; epithelial cell differentiation [GO:0030855] actin cytoskeleton [GO:0015629]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; vesicle [GO:0031982] actin filament binding [GO:0051015]; cadherin binding [GO:0045296] 0 60.891 DDGLFSGDPNWFPK 10.2771 9.35198 10.5532 0 9.12565 0 11.6997 11.4147 12.1499 11.6045 11.7831 12.2737 11.8134 12.0688 11.9425 12.6746 13.0987 12.4532 0 0 0 0 0 10.1131 12.735 12.1043 13.149 P37837 TALDO_HUMAN Transaldolase (EC 2.2.1.2) TALDO1 TAL TALDO TALDOR Homo sapiens (Human) "carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glyceraldehyde-3-phosphate metabolic process [GO:0019682]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634] monosaccharide binding [GO:0048029]; transaldolase activity [GO:0004801] 0.10556 1.1438 FAADAVK 0 0 0 0 0 0 8.96645 8.8867 0 12.425 9.23139 9.26875 9.11069 9.03815 9.38545 0 0 10.4114 10.0025 9.24141 0 0 9.32551 0 0 0 0 P38117 ETFB_HUMAN Electron transfer flavoprotein subunit beta (Beta-ETF) ETFB FP585 Homo sapiens (Human) amino acid catabolic process [GO:0009063]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; respiratory electron transport chain [GO:0022904] electron transfer flavoprotein complex [GO:0045251]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] electron transfer activity [GO:0009055] 0.8846 -0.14151 LNEPRYATLPNIMKAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3082 0 P38398 BRCA1_HUMAN Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1) BRCA1 RNF53 Homo sapiens (Human) cellular response to indole-3-methanol [GO:0071681]; cellular response to ionizing radiation [GO:0071479]; cellular response to tumor necrosis factor [GO:0071356]; centrosome cycle [GO:0007098]; chordate embryonic development [GO:0043009]; chromosome segregation [GO:0007059]; DNA damage response [GO:0006974]; DNA repair [GO:0006281]; DNA strand resection involved in replication fork processing [GO:0110025]; dosage compensation by inactivation of X chromosome [GO:0009048]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; fatty acid biosynthetic process [GO:0006633]; histone H2A K63-linked deubiquitination [GO:0070537]; histone H2A monoubiquitination [GO:0035518]; homologous recombination [GO:0035825]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; localization [GO:0051179]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; mitotic G2/M transition checkpoint [GO:0044818]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; negative regulation of centriole replication [GO:0046600]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of histone acetylation [GO:0035067]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; positive regulation of angiogenesis [GO:0045766]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of histone H3-K9 methylation [GO:0051574]; positive regulation of histone H4-K16 acetylation [GO:2000620]; positive regulation of histone H4-K20 methylation [GO:0070512]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; postreplication repair [GO:0006301]; protein autoubiquitination [GO:0051865]; protein K6-linked ubiquitination [GO:0085020]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; regulation of DNA damage checkpoint [GO:2000001]; regulation of DNA methylation [GO:0044030]; regulation of DNA repair [GO:0006282]; regulation of gene expression by genomic imprinting [GO:0006349]; regulation of transcription by RNA polymerase II [GO:0006357]; response to estrogen [GO:0043627]; response to ionizing radiation [GO:0010212] BRCA1-A complex [GO:0070531]; BRCA1-B complex [GO:0070532]; BRCA1-BARD1 complex [GO:0031436]; BRCA1-C complex [GO:0070533]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; DNA repair complex [GO:1990391]; gamma-tubulin ring complex [GO:0000931]; intracellular non-membrane-bounded organelle [GO:0043232]; lateral element [GO:0000800]; male germ cell nucleus [GO:0001673]; nuclear body [GO:0016604]; nuclear ubiquitin ligase complex [GO:0000152]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; ubiquitin ligase complex [GO:0000151]; XY body [GO:0001741] damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; p53 binding [GO:0002039]; RNA binding [GO:0003723]; RNA polymerase binding [GO:0070063]; transcription cis-regulatory region binding [GO:0000976]; transcription coactivator activity [GO:0003713]; tubulin binding [GO:0015631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.96938 -4.0978 AAERHPEK 0 0 0 0 0 0 0 0 0 9.47861 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P38432 COIL_HUMAN Coilin (p80-coilin) COIL CLN80 Homo sapiens (Human) spliceosomal snRNP assembly [GO:0000387] Cajal body [GO:0015030]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; membrane [GO:0016020]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] identical protein binding [GO:0042802]; U1 snRNA binding [GO:0030619]; U2 snRNA binding [GO:0030620] 0.96922 -3.5621 AVTDQTVSKKNK 0 0 0 0 0 0 0 0 0 0 10.1429 0 0 0 0 0 0 0 0 0 10.218 0 0 0 0 0 0 P38567 HYALP_HUMAN Hyaluronidase PH-20 (Hyal-PH20) (EC 3.2.1.35) (Hyaluronoglucosaminidase PH-20) (Sperm adhesion molecule 1) (Sperm surface protein PH-20) SPAM1 HYAL3 PH20 Homo sapiens (Human) binding of sperm to zona pellucida [GO:0007339]; carbohydrate metabolic process [GO:0005975]; cell adhesion [GO:0007155]; fusion of sperm to egg plasma membrane involved in single fertilization [GO:0007342]; hyaluronan catabolic process [GO:0030214] acrosomal vesicle [GO:0001669]; plasma membrane [GO:0005886] hyalurononglucosaminidase activity [GO:0004415] 0.85781 0.10092 FYCSCYSTLSCKEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8119 0 0 0 0 0 0 0 0 0 0 0 P38570 ITAE_HUMAN Integrin alpha-E (HML-1 antigen) (Integrin alpha-IEL) (Mucosal lymphocyte 1 antigen) (CD antigen CD103) [Cleaved into: Integrin alpha-E light chain; Integrin alpha-E heavy chain] ITGAE Homo sapiens (Human) cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; integrin-mediated signaling pathway [GO:0007229] external side of plasma membrane [GO:0009897]; integrin complex [GO:0008305]; plasma membrane [GO:0005886] integrin binding [GO:0005178]; metal ion binding [GO:0046872] 0.93357 -1.2899 DFISNMMR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.15028 0 0 0 0 0 0 0 0 0 0 0 0 P38571 LICH_HUMAN Lysosomal acid lipase/cholesteryl ester hydrolase (Acid cholesteryl ester hydrolase) (LAL) (EC 3.1.1.13) (Cholesteryl esterase) (Lipase A) (Sterol esterase) LIPA Homo sapiens (Human) acute inflammatory response [GO:0002526]; adaptive thermogenesis [GO:1990845]; adipose tissue development [GO:0060612]; ATP biosynthetic process [GO:0006754]; blood vessel endothelial cell differentiation [GO:0060837]; bone marrow development [GO:0048539]; cell morphogenesis [GO:0000902]; cell proliferation in bone marrow [GO:0071838]; cellular lipid biosynthetic process [GO:0097384]; cholesterol biosynthetic process [GO:0006695]; cholesterol efflux [GO:0033344]; cholesterol storage [GO:0010878]; common myeloid progenitor cell proliferation [GO:0035726]; defecation [GO:0030421]; determination of adult lifespan [GO:0008340]; endocytosis [GO:0006897]; endosome to lysosome transport [GO:0008333]; endothelial cell proliferation [GO:0001935]; energy homeostasis [GO:0097009]; fat cell proliferation [GO:0070341]; fatty acid metabolic process [GO:0006631]; gene expression [GO:0010467]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; hematopoietic progenitor cell differentiation [GO:0002244]; homeostasis of number of cells within a tissue [GO:0048873]; lipid catabolic process [GO:0016042]; lipid homeostasis [GO:0055088]; lipid import into cell [GO:0140354]; lipoprotein catabolic process [GO:0042159]; liver morphogenesis [GO:0072576]; low-density lipoprotein particle clearance [GO:0034383]; lung development [GO:0030324]; lysosome organization [GO:0007040]; macrophage homeostasis [GO:0061519]; mitochondrion organization [GO:0007005]; mitotic cell cycle [GO:0000278]; multicellular organismal-level chemical homeostasis [GO:0140962]; myeloid cell apoptotic process [GO:0033028]; myeloid cell differentiation [GO:0030099]; positive regulation of T cell receptor signaling pathway [GO:0050862]; reactive oxygen species biosynthetic process [GO:1903409]; regulation of mitochondrial membrane potential [GO:0051881]; respiratory burst involved in inflammatory response [GO:0002536]; response to cold [GO:0009409]; response to dietary excess [GO:0002021]; response to rapamycin [GO:1901355]; response to vitamin A [GO:0033189]; response to xenobiotic stimulus [GO:0009410]; small GTPase mediated signal transduction [GO:0007264]; spleen development [GO:0048536]; sterol metabolic process [GO:0016125]; T cell apoptotic process [GO:0070231]; T cell differentiation [GO:0030217]; T cell proliferation [GO:0042098]; tissue remodeling [GO:0048771]; TOR signaling [GO:0031929]; triglyceride metabolic process [GO:0006641]; triglyceride-rich lipoprotein particle clearance [GO:0071830]; vitamin A metabolic process [GO:0006776] cytosol [GO:0005829]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654] lipase activity [GO:0016298]; sterol esterase activity [GO:0004771] 0.72943 0.33658 IINLMRKYQ 0 0 0 0 0 0 0 0 0 9.85314 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P38606 VATA_HUMAN V-type proton ATPase catalytic subunit A (V-ATPase subunit A) (EC 7.1.2.2) (V-ATPase 69 kDa subunit) (Vacuolar ATPase isoform VA68) (Vacuolar proton pump subunit alpha) ATP6V1A ATP6A1 ATP6V1A1 VPP2 Homo sapiens (Human) cellular response to increased oxygen levels [GO:0036295]; endosomal lumen acidification [GO:0048388]; Golgi lumen acidification [GO:0061795]; intracellular iron ion homeostasis [GO:0006879]; intracellular pH reduction [GO:0051452]; lysosomal lumen acidification [GO:0007042]; proton transmembrane transport [GO:1902600]; regulation of macroautophagy [GO:0016241]; synaptic vesicle lumen acidification [GO:0097401]; vacuolar acidification [GO:0007035] "apical plasma membrane [GO:0016324]; clathrin-coated vesicle membrane [GO:0030665]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of synaptic vesicle membrane [GO:0098850]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; microvillus [GO:0005902]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; proton-transporting two-sector ATPase complex [GO:0016469]; proton-transporting V-type ATPase complex [GO:0033176]; secretory granule [GO:0030141]; transmembrane transporter complex [GO:1902495]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]" "ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]" 0.88651 -0.35698 AVETTAQSDNK 0 8.72663 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2333 10.5691 10.2154 0 0 0 0 0 0 P38646 GRP75_HUMAN "Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Mortalin) (MOT) (Peptide-binding protein 74) (PBP74)" HSPA9 GRP75 HSPA9B mt-HSP70 Homo sapiens (Human) chaperone cofactor-dependent protein refolding [GO:0051085]; erythrocyte differentiation [GO:0030218]; inner mitochondrial membrane organization [GO:0007007]; intracellular protein transport [GO:0006886]; iron-sulfur cluster assembly [GO:0016226]; negative regulation of apoptotic process [GO:0043066]; negative regulation of erythrocyte differentiation [GO:0045647]; negative regulation of hematopoietic stem cell differentiation [GO:1902037]; negative regulation of hemopoiesis [GO:1903707]; protein export from nucleus [GO:0006611]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; MIB complex [GO:0140275]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; SAM complex [GO:0001401]; TIM23 mitochondrial import inner membrane translocase complex [GO:0005744] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; heat shock protein binding [GO:0031072]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082] 0 36.557 AQFEGIVTDLIR 9.87109 9.96852 10.7484 0 8.97877 0 11.8445 11.6289 11.5752 10.9351 10.2708 0 8.96258 9.90588 0 8.83479 0 0 11.7209 10.9157 11.8514 11.1636 11.4369 9.70247 13.1034 12.8447 12.677 P38919 IF4A3_HUMAN "Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Eukaryotic translation initiation factor 4A isoform 3) (Nuclear matrix protein 265) (NMP 265) (hNMP 265) [Cleaved into: Eukaryotic initiation factor 4A-III, N-terminally processed]" EIF4A3 DDX48 KIAA0111 Homo sapiens (Human) "associative learning [GO:0008306]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to selenite ion [GO:0072715]; embryonic cranial skeleton morphogenesis [GO:0048701]; exploration behavior [GO:0035640]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of selenocysteine incorporation [GO:1904570]; negative regulation of selenocysteine insertion sequence binding [GO:1904574]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of translation [GO:0045727]; regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000622]; regulation of translation at postsynapse, modulating synaptic transmission [GO:0099578]; response to organic cyclic compound [GO:0014070]; rRNA processing [GO:0006364]" catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; exon-exon junction complex [GO:0035145]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794]; U2-type catalytic step 1 spliceosome [GO:0071006] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; mRNA binding [GO:0003729]; poly(A) binding [GO:0008143]; ribonucleoprotein complex binding [GO:0043021]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA stem-loop binding [GO:0035613]; selenocysteine insertion sequence binding [GO:0035368]; translation regulator activity [GO:0045182] 0 47.011 ATTATMATSGSAR 0 0 0 0 0 0 0 0 0 9.57099 9.11595 0 0 0 0 8.63452 0 0 0 0 0 0 0 0 0 0 0 P38935 SMBP2_HUMAN DNA-binding protein SMUBP-2 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase IGHMBP2) (Glial factor 1) (GF-1) (Immunoglobulin mu-binding protein 2) IGHMBP2 SMBP2 SMUBP2 Homo sapiens (Human) DNA duplex unwinding [GO:0032508]; RNA secondary structure unwinding [GO:0010501] axon [GO:0030424]; cytoplasm [GO:0005737]; growth cone [GO:0030426]; membrane [GO:0016020]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] "5'-3' DNA helicase activity [GO:0043139]; 5'-3' RNA helicase activity [GO:0032574]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent activity, acting on DNA [GO:0008094]; ATP-dependent activity, acting on RNA [GO:0008186]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; double-stranded DNA helicase activity [GO:0036121]; identical protein binding [GO:0042802]; ribosome binding [GO:0043022]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; transcription factor binding [GO:0008134]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]" 0.93007 -1.2404 TLTVQYRMHQAIMR 9.14601 9.19468 0 0 0 0 9.39896 9.24985 9.00809 8.5043 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P38936 CDN1A_HUMAN Cyclin-dependent kinase inhibitor 1 (CDK-interacting protein 1) (Melanoma differentiation-associated protein 6) (MDA-6) (p21) CDKN1A CAP20 CDKN1 CIP1 MDA6 PIC1 SDI1 WAF1 Homo sapiens (Human) "cellular response to amino acid starvation [GO:0034198]; cellular response to extracellular stimulus [GO:0031668]; cellular response to gamma radiation [GO:0071480]; cellular response to ionizing radiation [GO:0071479]; cellular response to UV-B [GO:0071493]; cellular senescence [GO:0090398]; DNA damage response [GO:0006974]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; G1/S transition of mitotic cell cycle [GO:0000082]; heart development [GO:0007507]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; keratinocyte differentiation [GO:0030216]; keratinocyte proliferation [GO:0043616]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of cardiac muscle tissue regeneration [GO:1905179]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cyclin-dependent protein kinase activity [GO:1904030]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of DNA biosynthetic process [GO:2000279]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression [GO:0010629]; negative regulation of phosphorylation [GO:0042326]; negative regulation of protein binding [GO:0032091]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; oncogene-induced cell senescence [GO:0090402]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein import into nucleus [GO:0006606]; Ras protein signal transduction [GO:0007265]; regulation of cell cycle [GO:0051726]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; replicative senescence [GO:0090399]; stress-induced premature senescence [GO:0090400]; tissue regeneration [GO:0042246]; wound healing [GO:0042060]" cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA-p21 complex [GO:0070557]; protein-containing complex [GO:0032991] cyclin binding [GO:0030332]; cyclin-dependent protein kinase activating kinase activity [GO:0019912]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; metal ion binding [GO:0046872]; molecular function activator activity [GO:0140677]; molecular function inhibitor activity [GO:0140678]; protein kinase binding [GO:0019901]; protein kinase inhibitor activity [GO:0004860]; protein sequestering activity [GO:0140311]; protein-containing complex binding [GO:0044877]; ubiquitin protein ligase binding [GO:0031625] 0.88206 -0.1155 RQTSMTDFYHSKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5694 P39019 RS19_HUMAN Small ribosomal subunit protein eS19 (40S ribosomal protein S19) RPS19 Homo sapiens (Human) "antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytoplasmic translation [GO:0002181]; defense response to Gram-negative bacterium [GO:0050829]; erythrocyte differentiation [GO:0030218]; killing of cells of another organism [GO:0031640]; maturation of SSU-rRNA [GO:0030490]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; monocyte chemotaxis [GO:0002548]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; nucleolus organization [GO:0007000]; positive regulation of respiratory burst involved in inflammatory response [GO:0060265]; response to extracellular stimulus [GO:0009991]; ribosomal small subunit assembly [GO:0000028]; ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364]; translation [GO:0006412]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; postsynaptic density [GO:0014069]; ribosome [GO:0005840]; small-subunit processome [GO:0032040] fibroblast growth factor binding [GO:0017134]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0 13.013 DLDRIAGQVAAANK 0 0 0 0 0 0 0 0 8.33771 0 0 0 10.238 0 8.55773 0 0 0 0 0 0 0 0 0 0 10.1367 0 P39023 RL3_HUMAN Large ribosomal subunit protein uL3 (60S ribosomal protein L3) (HIV-1 TAR RNA-binding protein B) (TARBP-B) RPL3 OK/SW-cl.32 Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cytoplasmic translation [GO:0002181]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; nucleolus [GO:0005730]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; synapse [GO:0045202] 5S rRNA binding [GO:0008097]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.78855 0.24813 FGHGRFQTMEEK 0 8.66203 0 0 0 0 0 0 9.79484 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P39059 COFA1_HUMAN Collagen alpha-1(XV) chain [Cleaved into: Restin (Endostatin-XV) (Related to endostatin) (Restin-I); Restin-2 (Restin-II); Restin-3 (Restin-III); Restin-4 (Restin-IV)] COL15A1 Homo sapiens (Human) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; extracellular matrix organization [GO:0030198]; signal transduction [GO:0007165] basement membrane [GO:0005604]; collagen type XV trimer [GO:0005582]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020] extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020] 0.92584 -0.96344 GEKGSWGLPGSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1862 0 0 0 0 0 10.6286 9.60261 0 0 0 0 P39060 COIA1_HUMAN Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1 (NC1)] COL18A1 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; negative regulation of cell population proliferation [GO:0008285]; notochord development [GO:0030903]; skeletal system development [GO:0001501]; visual perception [GO:0007601] basement membrane [GO:0005604]; collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872] 0.18442 0.95319 LQDLYSIVR 10.1854 9.76248 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P39086 GRIK1_HUMAN "Glutamate receptor ionotropic, kainate 1 (GluK1) (Excitatory amino acid receptor 3) (EAA3) (Glutamate receptor 5) (GluR-5) (GluR5)" GRIK1 GLUR5 Homo sapiens (Human) "central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; nervous system development [GO:0007399]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]" intracellular membrane-bounded organelle [GO:0043231]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; presynaptic membrane [GO:0042734] kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315] 0.95215 -1.476 SKISTYEK 0 0 0 0 0 0 0 0 0 0 0 10.7781 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P39656 OST48_HUMAN Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit (DDOST 48 kDa subunit) (Oligosaccharyl transferase 48 kDa subunit) DDOST KIAA0115 OST48 OK/SW-cl.45 Homo sapiens (Human) protein glycosylation [GO:0006486]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]; regulation of protein stability [GO:0031647]; response to cytokine [GO:0034097]; T cell activation [GO:0042110] azurophil granule membrane [GO:0035577]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; oligosaccharyltransferase complex [GO:0008250]; plasma membrane [GO:0005886] enzyme activator activity [GO:0008047] 0.0080645 2.0748 AAPGSQR 8.89361 9.0043 0 0 0 0 9.26252 9.86748 9.7123 9.45759 10.3938 9.59509 0 8.49961 0 8.91232 0 0 11.0505 10.1713 9.23184 0 9.10515 8.51001 10.2778 0 9.85301 P39687 AN32A_HUMAN Acidic leucine-rich nuclear phosphoprotein 32 family member A (Acidic nuclear phosphoprotein pp32) (pp32) (Leucine-rich acidic nuclear protein) (LANP) (Mapmodulin) (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Putative HLA-DR-associated protein I) (PHAPI) ANP32A C15orf1 LANP MAPM PHAP1 Homo sapiens (Human) intracellular signal transduction [GO:0035556]; nucleocytoplasmic transport [GO:0006913]; regulation of apoptotic process [GO:0042981] cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] histone binding [GO:0042393]; RNA binding [GO:0003723] 0.5742 0.47445 SLDLFNCEVTNLNDYR 0 0 0 0 0 9.75422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P39748 FEN1_HUMAN Flap endonuclease 1 (FEN-1) (EC 3.1.-.-) (DNase IV) (Flap structure-specific endonuclease 1) (Maturation factor 1) (MF1) (hFEN-1) FEN1 RAD2 Homo sapiens (Human) "base-excision repair, gap-filling [GO:0006287]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, removal of RNA primer [GO:0043137]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; memory [GO:0007613]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of sister chromatid cohesion [GO:0045876]; telomere maintenance via semi-conservative replication [GO:0032201]; UV protection [GO:0009650]" "chromosome, telomeric region [GO:0000781]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]" 5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; endonuclease activity [GO:0004519]; exonuclease activity [GO:0004527]; flap endonuclease activity [GO:0048256]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; RNA-DNA hybrid ribonuclease activity [GO:0004523] 0.92041 -0.92608 LIADVAPSAIR 0 0 0 0 0 0 0 0 0 9.84372 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P39880 CUX1_HUMAN Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (CDP/Cux p200) (Homeobox protein cux-1) [Cleaved into: CDP/Cux p110] CUX1 CUTL1 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of dendrite morphogenesis [GO:0050775]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96833 -3.6377 APDVEQAIEVLTRSSLEVELAAKER 9.7322 0 0 0 0 0 0 0 0 11.0712 10.0329 0 0 0 9.54249 11.2572 0 0 0 0 0 0 0 0 0 9.23197 10.4986 P39900 MMP12_HUMAN Macrophage metalloelastase (MME) (EC 3.4.24.65) (Macrophage elastase) (ME) (hME) (Matrix metalloproteinase-12) (MMP-12) MMP12 HME Homo sapiens (Human) "bronchiole development [GO:0060435]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; lung alveolus development [GO:0048286]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]" cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634] calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter sequence-specific DNA binding [GO:0001046]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270] 0.93032 -1.2385 AVMFPTYK 0 0 0 0 0 0 0 0 0 0 11.5383 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.7383 0 P40123 CAP2_HUMAN Adenylyl cyclase-associated protein 2 (CAP 2) CAP2 Homo sapiens (Human) actin filament organization [GO:0007015]; activation of adenylate cyclase activity [GO:0007190]; cAMP-mediated signaling [GO:0019933]; cell morphogenesis [GO:0000902]; establishment or maintenance of cell polarity [GO:0007163]; presynaptic actin cytoskeleton organization [GO:0099140]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] actin binding [GO:0003779]; adenylate cyclase binding [GO:0008179]; identical protein binding [GO:0042802] 0.89769 -0.549 GKVNSIIIDNCK 0 0 0 0 0 0 0 0 9.51737 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P40145 ADCY8_HUMAN Adenylate cyclase type 8 (EC 4.6.1.1) (ATP pyrophosphate-lyase 8) (Adenylate cyclase type VIII) (Adenylyl cyclase 8) (AC8) (Ca(2+)/calmodulin-activated adenylyl cyclase) ADCY8 Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP biosynthetic process [GO:0006171]; cellular response to calcium ion [GO:0071277]; cellular response to forskolin [GO:1904322]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to morphine [GO:0071315]; G protein-coupled opioid receptor signaling pathway [GO:0038003]; glucose homeostasis [GO:0042593]; glucose mediated signaling pathway [GO:0010255]; intracellular signal transduction [GO:0035556]; learning or memory [GO:0007611]; locomotory behavior [GO:0007626]; long-term memory [GO:0007616]; memory [GO:0007613]; neuroinflammatory response [GO:0150076]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of long-term synaptic depression [GO:1900454]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of synaptic plasticity [GO:0031915]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of cellular response to stress [GO:0080135]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of insulin secretion [GO:0050796]; signal transduction [GO:0007165] apical plasma membrane [GO:0016324]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; caveola [GO:0005901]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; dendrite [GO:0030425]; excitatory synapse [GO:0060076]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; postsynaptic density [GO:0014069]; presynaptic active zone [GO:0048786]; presynaptic membrane [GO:0042734]; Schaffer collateral - CA1 synapse [GO:0098685] actin binding [GO:0003779]; adenylate cyclase activity [GO:0004016]; ATP binding [GO:0005524]; calcium- and calmodulin-responsive adenylate cyclase activity [GO:0008294]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; molecular function activator activity [GO:0140677]; molecular function inhibitor activity [GO:0140678]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein phosphatase 2A binding [GO:0051721] 0.9699 -5.2997 DSSLEHKYSQMR 0 11.0743 0 12.1705 0 0 11.5013 0 0 14.488 0 0 0 0 0 0 0 0 0 0 8.38952 0 0 0 0 10.5337 0 P40189 IL6RB_HUMAN Interleukin-6 receptor subunit beta (IL-6 receptor subunit beta) (IL-6R subunit beta) (IL-6R-beta) (IL-6RB) (CDw130) (Interleukin-6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin-M receptor subunit alpha) (CD antigen CD130) IL6ST Homo sapiens (Human) ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; glycogen metabolic process [GO:0005977]; interleukin-11-mediated signaling pathway [GO:0038154]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-6-mediated signaling pathway [GO:0070102]; intestinal epithelial cell development [GO:0060576]; leukemia inhibitory factor signaling pathway [GO:0048861]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; negative regulation of neuron apoptotic process [GO:0043524]; oncostatin-M-mediated signaling pathway [GO:0038165]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of platelet aggregation [GO:1901731]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; response to cytokine [GO:0034097]; T-helper 17 cell lineage commitment [GO:0072540] ciliary neurotrophic factor receptor complex [GO:0070110]; dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; oncostatin-M receptor complex [GO:0005900]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] ciliary neurotrophic factor receptor activity [GO:0004897]; ciliary neurotrophic factor receptor binding [GO:0005127]; coreceptor activity [GO:0015026]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; identical protein binding [GO:0042802]; interleukin-11 binding [GO:0019970]; interleukin-11 receptor activity [GO:0004921]; interleukin-27 receptor activity [GO:0045509]; protein tyrosine kinase activator activity [GO:0030296]; scaffold protein binding [GO:0097110] 0.92081 -1.116 EQYTIINR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2671 0 0 0 0 0 10.5379 8.6995 0 0 0 P40197 GPV_HUMAN Platelet glycoprotein V (GPV) (Glycoprotein 5) (CD antigen CD42d) GP5 Homo sapiens (Human) "blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; megakaryocyte development [GO:0035855]; positive regulation of platelet activation [GO:0010572]; release of sequestered calcium ion into cytosol [GO:0051209]" extracellular exosome [GO:0070062]; glycoprotein Ib-IX-V complex [GO:1990779]; plasma membrane [GO:0005886] 0.94008 -1.3 QVSLRRNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3431 0 0 0 11.1599 0 0 0 0 P40200 TACT_HUMAN T-cell surface protein tactile (Cell surface antigen CD96) (T cell-activated increased late expression protein) (CD antigen CD96) CD96 Homo sapiens (Human) cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; immune response [GO:0006955]; inflammatory response [GO:0006954]; negative regulation of natural killer cell cytokine production [GO:0002728]; negative regulation of type II interferon production [GO:0032689]; response to lipopolysaccharide [GO:0032496] cytoplasm [GO:0005737]; plasma membrane [GO:0005886] 0.3719 0.72845 EGIYITNEERK 0 0 0 0 0 0 0 0 0 0 0 10.8249 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P40222 TXLNA_HUMAN Alpha-taxilin TXLNA TXLN Homo sapiens (Human) B cell activation [GO:0042113]; exocytosis [GO:0006887] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020] syntaxin binding [GO:0019905] 0.96144 -2.0643 DLQQQLVDAK 0 0 0 0 11.63 11.6964 16.2018 0 16.1514 0 0 0 0 0 0 0 15.014 0 0 10.2452 0 0 0 0 15.2435 0 0 P40227 TCPZ_HUMAN T-complex protein 1 subunit zeta (TCP-1-zeta) (Acute morphine dependence-related protein 2) (CCT-zeta-1) (HTR3) (Tcp20) CCT6A CCT6 CCTZ Homo sapiens (Human) chaperone-mediated protein folding [GO:0061077]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of protein localization to Cajal body [GO:1904871]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein folding [GO:0006457]; protein stabilization [GO:0050821] chaperonin-containing T-complex [GO:0005832]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; WD40-repeat domain binding [GO:0071987] 0.020737 1.6323 AAVKTLNPK 0 0 0 0 0 9.55013 10.4522 10.9501 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2996 9.34596 9.35771 0 0 0 P40238 TPOR_HUMAN Thrombopoietin receptor (TPO-R) (Myeloproliferative leukemia protein) (Proto-oncogene c-Mpl) (CD antigen CD110) MPL TPOR Homo sapiens (Human) basophil homeostasis [GO:1990960]; cellular response to hypoxia [GO:0071456]; eosinophil homeostasis [GO:1990959]; immunoglobulin mediated immune response [GO:0016064]; monocyte homeostasis [GO:0035702]; neutrophil homeostasis [GO:0001780]; platelet aggregation [GO:0070527]; positive regulation of lymphocyte proliferation [GO:0050671]; positive regulation of platelet formation [GO:1905221]; thrombopoietin-mediated signaling pathway [GO:0038163] cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886] thrombopoietin receptor activity [GO:0038164] 0.79448 0.2441 TNPGLQTPQFSR 0 0 0 0 0 0 0 0 0 0 11.981 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P40261 NNMT_HUMAN Nicotinamide N-methyltransferase (EC 2.1.1.1) NNMT Homo sapiens (Human) animal organ regeneration [GO:0031100]; methylation [GO:0032259]; NAD biosynthesis via nicotinamide riboside salvage pathway [GO:0034356]; nicotinamide metabolic process [GO:0006769]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of protein deacetylation [GO:0090312]; response to organonitrogen compound [GO:0010243]; response to xenobiotic stimulus [GO:0009410] cytosol [GO:0005829] nicotinamide N-methyltransferase activity [GO:0008112]; pyridine N-methyltransferase activity [GO:0030760] 0.05042 1.4202 DTYLSHFNPRDYLEK 0 0 0 0 0 0 0 0 0 11.1492 0 0 0 0 0 11.0061 10.4376 0 0 0 0 0 0 0 0 0 0 P40305 IFI27_HUMAN "Interferon alpha-inducible protein 27, mitochondrial (p27) (Interferon alpha-induced 11.5 kDa protein) (Interferon-stimulated gene 12a protein) (ISG12(a)) (ISG12A)" IFI27 Homo sapiens (Human) apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; innate immune response [GO:0045087]; modulation by host of viral genome replication [GO:0044827]; negative regulation of transcription by RNA polymerase II [GO:0000122]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; pyroptosis [GO:0070269]; regulation of protein export from nucleus [GO:0046825]; type I interferon-mediated signaling pathway [GO:0060337] endoplasmic reticulum membrane [GO:0005789]; mitochondrial membrane [GO:0031966]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear inner membrane [GO:0005637] identical protein binding [GO:0042802]; lamin binding [GO:0005521]; molecular adaptor activity [GO:0060090]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629] 0.91477 -0.78445 EASALTSSAVTSVAKVVR 9.27349 9.29467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P40394 ADH7_HUMAN All-trans-retinol dehydrogenase [NAD(+)] ADH7 (EC 1.1.1.105) (Alcohol dehydrogenase class 4 mu/sigma chain) (EC 1.1.1.1) (Alcohol dehydrogenase class IV mu/sigma chain) (Gastric alcohol dehydrogenase) (Omega-hydroxydecanoate dehydrogenase ADH7) (EC 1.1.1.66) (Retinol dehydrogenase) ADH7 Homo sapiens (Human) ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; response to bacterium [GO:0009617]; response to ethanol [GO:0045471]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572] cytosol [GO:0005829]; plasma membrane [GO:0005886] "alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; aldehyde oxidase activity [GO:0004031]; ethanol binding [GO:0035276]; NAD-retinol dehydrogenase activity [GO:0004745]; omega-hydroxydecanoate dehydrogenase activity [GO:0050153]; receptor antagonist activity [GO:0048019]; retinol binding [GO:0019841]; zinc ion binding [GO:0008270]" 0.96298 -2.6624 DRMGTAGKVIK 10.0213 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P40426 PBX3_HUMAN Pre-B-cell leukemia transcription factor 3 (Homeobox protein PBX3) PBX3 Homo sapiens (Human) adult locomotory behavior [GO:0008344]; animal organ morphogenesis [GO:0009887]; anterior compartment pattern formation [GO:0007387]; brain development [GO:0007420]; dorsal spinal cord development [GO:0021516]; embryonic organ development [GO:0048568]; eye development [GO:0001654]; neuron development [GO:0048666]; posterior compartment specification [GO:0007388]; regulation of respiratory gaseous exchange by nervous system process [GO:0002087]; regulation of transcription by RNA polymerase II [GO:0006357]; respiratory gaseous exchange by respiratory system [GO:0007585] chromatin [GO:0000785]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.9164 -0.76756 NIGKFQEEANLYAAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.80289 0 0 0 P40429 RL13A_HUMAN Large ribosomal subunit protein uL13 (23 kDa highly basic protein) (60S ribosomal protein L13a) RPL13A Homo sapiens (Human) cellular response to type II interferon [GO:0071346]; cytoplasmic translation [GO:0002181]; homeostatic process [GO:0042592]; lung morphogenesis [GO:0060425]; macrophage chemotaxis [GO:0048246]; negative regulation of formation of translation preinitiation complex [GO:1901194]; negative regulation of translation [GO:0017148]; response to lipopolysaccharide [GO:0032496]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; focal adhesion [GO:0005925]; GAIT complex [GO:0097452]; large ribosomal subunit [GO:0015934]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; ribosome [GO:0005840]; synapse [GO:0045202] mRNA binding [GO:0003729]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.006006 2.4964 LAHEVGWK 0 0 8.63793 0 0 8.90497 8.94351 9.16548 9.84834 0 0 0 0 0 0 10.7204 0 10.3982 0 0 0 0 0 0 0 0 0 P40617 ARL4A_HUMAN ADP-ribosylation factor-like protein 4A ARL4A ARL4 Homo sapiens (Human) brown fat cell differentiation [GO:0050873]; intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.69329 0.38314 QDLRNSLSLSEIEK 0 0 0 0 8.85212 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P40692 MLH1_HUMAN DNA mismatch repair protein Mlh1 (MutL protein homolog 1) MLH1 COCA2 Homo sapiens (Human) double-strand break repair via nonhomologous end joining [GO:0006303]; female meiosis chromosome segregation [GO:0016321]; homologous chromosome pairing at meiosis [GO:0007129]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; isotype switching [GO:0045190]; male meiosis chromosome segregation [GO:0007060]; meiotic metaphase I plate congression [GO:0043060]; meiotic spindle midzone assembly [GO:0051257]; meiotic telomere clustering [GO:0045141]; mismatch repair [GO:0006298]; negative regulation of mitotic recombination [GO:0045950]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; oogenesis [GO:0048477]; positive regulation of isotype switching to IgA isotypes [GO:0048298]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; resolution of meiotic recombination intermediates [GO:0000712]; response to bacterium [GO:0009617]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spermatogenesis [GO:0007283] chiasma [GO:0005712]; chromosome [GO:0005694]; late recombination nodule [GO:0005715]; male germ cell nucleus [GO:0001673]; membrane [GO:0016020]; MutLalpha complex [GO:0032389]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; synaptonemal complex [GO:0000795] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent DNA damage sensor activity [GO:0140664]; chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; guanine/thymine mispair binding [GO:0032137] 0.93874 -1.2967 KCIFLLFINHR 0 0 0 0 0 0 0 0 0 9.53251 12.9964 0 0 0 0 0 0 0 0 0 8.95542 0 0 0 0 0 0 P40818 UBP8_HUMAN Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (hUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) USP8 KIAA0055 UBPY Homo sapiens (Human) "cellular response to dexamethasone stimulus [GO:0071549]; cellular response to nerve growth factor stimulus [GO:1990090]; endosome organization [GO:0007032]; mitotic cytokinesis [GO:0000281]; negative regulation of lysosomal protein catabolic process [GO:1905166]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; Ras protein signal transduction [GO:0007265]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein stability [GO:0031647]; ubiquitin-dependent protein catabolic process [GO:0006511]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; extrinsic component of endosome membrane [GO:0031313]; extrinsic component of plasma membrane [GO:0019897]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; nucleus [GO:0005634]; postsynaptic density [GO:0014069] cadherin binding [GO:0045296]; cysteine-type deubiquitinase activity [GO:0004843]; cysteine-type endopeptidase activity [GO:0004197]; SH3 domain binding [GO:0017124] 0.8868 -0.35507 ALWTGQYRYISPK 0 0 0 0 0 0 0 0 0 9.4709 0 0 0 0 0 0 0 0 0 9.97284 0 0 0 0 0 0 0 P40855 PEX19_HUMAN Peroxisomal biogenesis factor 19 (33 kDa housekeeping protein) (Peroxin-19) (Peroxisomal farnesylated protein) PEX19 HK33 PXF OK/SW-cl.22 Homo sapiens (Human) chaperone-mediated protein folding [GO:0061077]; establishment of protein localization to peroxisome [GO:0072663]; negative regulation of lipid binding [GO:1900131]; peroxisome fission [GO:0016559]; peroxisome membrane biogenesis [GO:0016557]; peroxisome organization [GO:0007031]; protein import into peroxisome membrane [GO:0045046]; protein stabilization [GO:0050821]; protein targeting to peroxisome [GO:0006625] brush border membrane [GO:0031526]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991] ATPase binding [GO:0051117]; peroxisome membrane class-1 targeting sequence binding [GO:0036105]; peroxisome membrane targeting sequence binding [GO:0033328]; protein carrier chaperone [GO:0140597] 0.63109 0.39911 SPGDTAK 0 0 0 0 0 0 0 0 0 9.17315 0 0 0 0 0 0 0 0 8.74896 0 8.55509 0 9.0141 0 0 0 0 P40879 S26A3_HUMAN Chloride anion exchanger (Down-regulated in adenoma) (Protein DRA) (Solute carrier family 26 member 3) SLC26A3 DRA Homo sapiens (Human) cellular response to cAMP [GO:0071320]; intracellular pH elevation [GO:0051454]; membrane hyperpolarization [GO:0060081]; monoatomic anion transport [GO:0006820]; monoatomic ion transport [GO:0006811]; sperm capacitation [GO:0048240] apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; membrane [GO:0016020]; plasma membrane [GO:0005886]; sperm midpiece [GO:0097225] bicarbonate transmembrane transporter activity [GO:0015106]; chloride transmembrane transporter activity [GO:0015108]; chloride:bicarbonate antiporter activity [GO:0140900]; oxalate transmembrane transporter activity [GO:0019531]; secondary active sulfate transmembrane transporter activity [GO:0008271]; solute:inorganic anion antiporter activity [GO:0005452]; sulfate transmembrane transporter activity [GO:0015116] 0.95984 -1.7291 FNPSQEKDGKIDFTINTNGGLR 0 9.00874 0 0 0 0 11.3501 0 0 0 0 9.25087 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P40925 MDHC_HUMAN "Malate dehydrogenase, cytoplasmic (EC 1.1.1.37) (Aromatic alpha-keto acid reductase) (KAR) (EC 1.1.1.96) (Cytosolic malate dehydrogenase)" MDH1 MDHA Homo sapiens (Human) gluconeogenesis [GO:0006094]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; NADP metabolic process [GO:0006739]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099] centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615] diiodophenylpyruvate reductase activity [GO:0047860]; hydroxyphenylpyruvate reductase activity [GO:0047995]; L-malate dehydrogenase activity [GO:0030060]; malic enzyme activity [GO:0004470] 0 2.7782 ELTEEKESAFEFLSSA 9.5709 9.34372 9.32894 0 9.05561 8.85278 10.2953 10.2993 10.345 8.85577 0 0 0 9.84281 9.72974 10.3397 0 9.87073 10.5213 11.2849 11.0846 10.2137 10.161 10.0309 11.673 11.5078 11.7944 P40926 MDHM_HUMAN "Malate dehydrogenase, mitochondrial (EC 1.1.1.37)" MDH2 Homo sapiens (Human) aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634] L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723] 0 84.782 AGAGSATLSMAYAGAR 10.2086 10.5953 10.7505 0 0 0 0 8.57331 8.50791 11.884 11.1772 12.2296 13.717 9.1108 11.578 11.2414 12.4053 11.8329 10.6393 12.0811 10.52 10.1529 10.8699 10.8131 11.9464 11.6221 11.2231 P40933 IL15_HUMAN Interleukin-15 (IL-15) IL15 Homo sapiens (Human) aging [GO:0007568]; cell maturation [GO:0048469]; cell-cell signaling [GO:0007267]; cellular response to vitamin D [GO:0071305]; extrathymic T cell selection [GO:0045062]; hyaluronan metabolic process [GO:0030212]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-15-mediated signaling pathway [GO:0035723]; lymph node development [GO:0048535]; macrophage differentiation [GO:0030225]; natural killer cell differentiation [GO:0001779]; natural killer cell proliferation [GO:0001787]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neutrophil activation [GO:0042119]; NK T cell proliferation [GO:0001866]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production [GO:0001819]; positive regulation of immune response [GO:0050778]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein O-linked glycosylation [GO:1904100]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of defense response to virus by host [GO:0050691]; regulation of T cell differentiation [GO:0045580]; signal transduction [GO:0007165]; skeletal muscle atrophy [GO:0014732]; tyrosine phosphorylation of STAT protein [GO:0007260] cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654] cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126] 0.56048 0.52139 ECEELEEK 0 0 0 0 0 9.57824 0 0 0 0 0 11.3712 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P40937 RFC5_HUMAN Replication factor C subunit 5 (Activator 1 36 kDa subunit) (A1 36 kDa subunit) (Activator 1 subunit 5) (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) RFC5 Homo sapiens (Human) DNA duplex unwinding [GO:0032508]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA-templated DNA replication [GO:0006261]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264] Ctf18 RFC-like complex [GO:0031390]; DNA replication factor C complex [GO:0005663]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA binding [GO:0003677]; enzyme binding [GO:0019899] 0.95212 -1.4538 QLYKDKEFGSMVLELNASDDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.89689 0 0 0 P40939 ECHA_HUMAN "Trifunctional enzyme subunit alpha, mitochondrial (78 kDa gastrin-binding protein) (Monolysocardiolipin acyltransferase) (EC 2.3.1.-) (TP-alpha) [Includes: Long-chain enoyl-CoA hydratase (EC 4.2.1.17); Long chain 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211)]" HADHA HADH Homo sapiens (Human) cardiolipin acyl-chain remodeling [GO:0035965]; fatty acid beta-oxidation [GO:0006635]; response to insulin [GO:0032868]; response to xenobiotic stimulus [GO:0009410] mitochondrial fatty acid beta-oxidation multienzyme complex [GO:0016507]; mitochondrial inner membrane [GO:0005743]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739] 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; enoyl-CoA hydratase activity [GO:0004300]; fatty-acyl-CoA binding [GO:0000062]; long-chain-3-hydroxyacyl-CoA dehydrogenase activity [GO:0016509]; NAD+ binding [GO:0070403]; protein-containing complex binding [GO:0044877] 0 15.463 DATLTALDR 0 0 0 11.6353 11.6247 11.7694 10.5379 10.8595 10.0286 0 8.92336 0 8.69275 0 0 0 0 0 10.3947 10.3671 9.48788 10.7179 9.22144 10.3966 11.7957 11.3489 12.0421 P40967 PMEL_HUMAN Melanocyte protein PMEL (ME20-M) (ME20M) (Melanocyte protein Pmel 17) (Melanocytes lineage-specific antigen GP100) (Melanoma-associated ME20 antigen) (P1) (P100) (Premelanosome protein) (Silver locus protein homolog) [Cleaved into: M-alpha (95 kDa melanocyte-specific secreted glycoprotein) (P26) (Secreted melanoma-associated ME20 antigen) (ME20-S) (ME20S); M-beta] PMEL D12S53E PMEL17 SILV Homo sapiens (Human) melanin biosynthetic process [GO:0042438]; melanosome organization [GO:0032438] "cis-Golgi network membrane [GO:0033106]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; melanosome [GO:0042470]; melanosome membrane [GO:0033162]; multivesicular body membrane [GO:0032585]; multivesicular body, internal vesicle [GO:0097487]; plasma membrane [GO:0005886]" identical protein binding [GO:0042802] 0.83679 0.19455 QVPLDCVLYR 10.4148 0 0 0 0 0 10.3318 10.3934 0 9.54963 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P41002 CCNF_HUMAN Cyclin-F (F-box only protein 1) CCNF FBX1 FBXO1 Homo sapiens (Human) cell division [GO:0051301]; mitotic cell cycle phase transition [GO:0044772]; negative regulation of centrosome duplication [GO:0010826]; placenta development [GO:0001890]; protein ubiquitination [GO:0016567]; re-entry into mitotic cell cycle [GO:0000320]; regulation of cell cycle [GO:0051726]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] cell junction [GO:0030054]; centriole [GO:0005814]; centrosome [GO:0005813]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; SCF ubiquitin ligase complex [GO:0019005] anaphase-promoting complex binding [GO:0010997]; cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538] 0.56414 0.50492 CFCYPTK 11.0177 10.993 11.2409 0 0 0 10.686 10.5532 10.4652 11.9469 11.8028 11.6001 0 0 0 0 0 0 9.84663 0 0 0 0 0 0 0 0 P41143 OPRD_HUMAN Delta-type opioid receptor (D-OR-1) (DOR-1) OPRD1 OPRD Homo sapiens (Human) "adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hypoxia [GO:0071456]; cellular response to toxic substance [GO:0097237]; eating behavior [GO:0042755]; G protein-coupled opioid receptor signaling pathway [GO:0038003]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; immune response [GO:0006955]; negative regulation of gene expression [GO:0010629]; negative regulation of protein-containing complex assembly [GO:0031333]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; regulation of calcium ion transport [GO:0051924]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of sensory perception of pain [GO:0051930]" axon terminus [GO:0043679]; dendrite membrane [GO:0032590]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; neuronal dense core vesicle [GO:0098992]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; presynaptic membrane [GO:0042734]; spine apparatus [GO:0097444]; synaptic vesicle membrane [GO:0030672] G protein-coupled enkephalin receptor activity [GO:0038046]; G protein-coupled opioid receptor activity [GO:0004985]; receptor serine/threonine kinase binding [GO:0033612] 0.93337 -1.2837 LLSGSKEKDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.34494 0 P41146 OPRX_HUMAN Nociceptin receptor (Kappa-type 3 opioid receptor) (KOR-3) (Orphanin FQ receptor) OPRL1 OOR ORL1 Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; conditioned place preference [GO:1990708]; eating behavior [GO:0042755]; estrous cycle [GO:0044849]; G protein-coupled opioid receptor signaling pathway [GO:0038003]; negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0106072]; negative regulation of blood pressure [GO:0045776]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of voltage-gated calcium channel activity [GO:1901386]; neuropeptide signaling pathway [GO:0007218]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of gastric acid secretion [GO:0060454]; positive regulation of sensory perception of pain [GO:1904058]; positive regulation of urine volume [GO:0035810]; regulation of locomotor rhythm [GO:1904059]; response to estradiol [GO:0032355]; sensory perception [GO:0007600]; sensory perception of pain [GO:0019233] cytoplasmic vesicle [GO:0031410]; neuron projection [GO:0043005]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; nociceptin receptor activity [GO:0001626] 0.91021 -0.74766 DVALACKTSETVPRPA 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9201 0 0 P41162 ETV3_HUMAN ETS translocation variant 3 (ETS domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor) ETV3 METS PE1 Homo sapiens (Human) cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; negative regulation of cell population proliferation [GO:0008285]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription repressor complex [GO:0090571] "DEAD/H-box RNA helicase binding [GO:0017151]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96157 -2.0248 AGCSIVEKPEGGGGYQFPDWAYK 9.65646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.56 0 0 0 0 0 0 0 0 0 0 P41180 CASR_HUMAN Extracellular calcium-sensing receptor (CaR) (CaSR) (hCasR) (Parathyroid cell calcium-sensing receptor 1) (PCaR1) CASR GPRC2A PCAR1 Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; anatomical structure morphogenesis [GO:0009653]; apoptotic process [GO:0006915]; bile acid secretion [GO:0032782]; branching morphogenesis of an epithelial tube [GO:0048754]; calcium ion import [GO:0070509]; cellular response to glucose stimulus [GO:0071333]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hypoxia [GO:0071456]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to peptide [GO:1901653]; cellular response to vitamin D [GO:0071305]; chemosensory behavior [GO:0007635]; chloride transmembrane transport [GO:1902476]; detection of calcium ion [GO:0005513]; fat pad development [GO:0060613]; G protein-coupled receptor signaling pathway [GO:0007186]; intracellular calcium ion homeostasis [GO:0006874]; JNK cascade [GO:0007254]; ossification [GO:0001503]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of ATP-dependent activity [GO:0032781]; positive regulation of calcium ion import [GO:0090280]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin secretion [GO:0032024]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of vasoconstriction [GO:0045907]; regulation of calcium ion transport [GO:0051924]; response to fibroblast growth factor [GO:0071774]; response to ischemia [GO:0002931]; vasodilation [GO:0042311] apical plasma membrane [GO:0016324]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886] amino acid binding [GO:0016597]; calcium ion binding [GO:0005509]; G protein-coupled receptor activity [GO:0004930]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; phosphatidylinositol phospholipase C activity [GO:0004435]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; transmembrane transporter binding [GO:0044325] 0.96259 -2.5039 EVGYYNVYAKKGER 0 0 0 9.43888 0 9.52552 10.6021 0 11.1058 11.1171 0 11.4605 0 10.2087 0 0 0 0 0 0 0 0 0 0 0 0 0 P41182 BCL6_HUMAN B-cell lymphoma 6 protein (BCL-6) (B-cell lymphoma 5 protein) (BCL-5) (Protein LAZ-3) (Zinc finger and BTB domain-containing protein 27) (Zinc finger protein 51) BCL6 BCL5 LAZ3 ZBTB27 ZNF51 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; B cell proliferation [GO:0042100]; cell morphogenesis [GO:0000902]; cell motility [GO:0048870]; cell-matrix adhesion [GO:0007160]; DNA damage response [GO:0006974]; erythrocyte development [GO:0048821]; germinal center formation [GO:0002467]; heterochromatin formation [GO:0031507]; inflammatory response [GO:0006954]; isotype switching to IgE isotypes [GO:0048289]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of cell growth [GO:0030308]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cellular senescence [GO:2000773]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of isotype switching to IgE isotypes [GO:0048294]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mitotic cell cycle DNA replication [GO:1903464]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of plasma cell differentiation [GO:1900099]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; plasma cell differentiation [GO:0002317]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of regulatory T cell differentiation [GO:0045591]; protein localization [GO:0008104]; pyramidal neuron differentiation [GO:0021859]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production [GO:0001817]; regulation of germinal center formation [GO:0002634]; regulation of GTPase activity [GO:0043087]; regulation of immune response [GO:0050776]; regulation of immune system process [GO:0002682]; regulation of inflammatory response [GO:0050727]; regulation of memory T cell differentiation [GO:0043380]; regulation of T cell proliferation [GO:0042129]; Rho protein signal transduction [GO:0007266]; spermatogenesis [GO:0007283]; T-helper 2 cell differentiation [GO:0045064]; transcription by RNA polymerase II [GO:0006366]; type 2 immune response [GO:0042092] Golgi apparatus [GO:0005794]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382] "chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor binding [GO:0140297]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; intronic transcription regulatory region sequence-specific DNA binding [GO:0001161]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription corepressor binding [GO:0001222]" 0.7266 0.34773 CETCGAR 10.223 0 0 10.0664 0 0 10.1614 0 10.1866 0 0 0 0 0 0 9.07871 0 0 0 0 0 0 0 0 0 0 0 P41212 ETV6_HUMAN Transcription factor ETV6 (ETS translocation variant 6) (ETS-related protein Tel1) (Tel) ETV6 TEL TEL1 Homo sapiens (Human) hematopoietic stem cell proliferation [GO:0071425]; mesenchymal cell apoptotic process [GO:0097152]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of transcription by RNA polymerase II [GO:0006357]; vitellogenesis [GO:0007296] chromatin [GO:0000785]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; protein domain specific binding [GO:0019904]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.92725 -1.1932 HYYKLNIIR 0 0 0 0 0 0 0 9.35944 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P41214 EIF2D_HUMAN Eukaryotic translation initiation factor 2D (eIF2d) (Hepatocellular carcinoma-associated antigen 56) (Ligatin) EIF2D HCA56 LGTN Homo sapiens (Human) formation of translation preinitiation complex [GO:0001731]; intracellular protein transport [GO:0006886]; IRES-dependent viral translational initiation [GO:0075522]; ribosome disassembly [GO:0032790] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear body [GO:0016604] RNA binding [GO:0003723]; signaling receptor activity [GO:0038023]; translation initiation factor activity [GO:0003743] 0.9647 -2.2843 GVESIVAVDWKHPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.72137 P41218 MNDA_HUMAN Myeloid cell nuclear differentiation antigen MNDA Homo sapiens (Human) activation of innate immune response [GO:0002218]; B cell receptor signaling pathway [GO:0050853]; cellular defense response [GO:0006968]; cellular response to interferon-beta [GO:0035458]; DNA damage response [GO:0006974]; negative regulation of B cell proliferation [GO:0030889]; positive regulation of apoptotic process [GO:0043065]; positive regulation of interleukin-1 beta production [GO:0032731] azurophil granule lumen [GO:0035578]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] double-stranded DNA binding [GO:0003690] 0.9491 -1.3752 ITDLMEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3568 0 0 0 0 0 0 0 0 P41219 PERI_HUMAN Peripherin (Neurofilament 4) PRPH NEF4 PRPH1 Homo sapiens (Human) axon [GO:0030424]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; membrane [GO:0016020]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; type III intermediate filament [GO:0045098] structural molecule activity [GO:0005198] 0.8096 0.23244 KLLEGEESR 0 0 11.0612 8.80151 8.65864 0 0 0 0 0 0 0 0 0 0 0 0 9.96996 0 0 9.95015 0 0 10.3457 0 0 9.80429 P41220 RGS2_HUMAN Regulator of G-protein signaling 2 (RGS2) (Cell growth-inhibiting gene 31 protein) (G0/G1 switch regulatory protein 8) RGS2 G0S8 GIG31 Homo sapiens (Human) brain development [GO:0007420]; brown fat cell differentiation [GO:0050873]; cell cycle [GO:0007049]; G protein-coupled receptor signaling pathway [GO:0007186]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process [GO:0140194]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of glycine import across plasma membrane [GO:1900924]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of phospholipase activity [GO:0010519]; negative regulation of translation [GO:0017148]; ovulation [GO:0030728]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of neuron projection development [GO:0010976]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; relaxation of cardiac muscle [GO:0055119]; relaxation of vascular associated smooth muscle [GO:0060087]; response to amphetamine [GO:0001975]; response to ethanol [GO:0045471]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886] adenylate cyclase inhibitor activity [GO:0010855]; beta-tubulin binding [GO:0048487]; calmodulin binding [GO:0005516]; G-protein alpha-subunit binding [GO:0001965]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924] 0.95263 -1.494 SAGSGHKSEEK 0 0 0 0 0 0 0 0 0 0 0 8.93009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P41226 UBA7_HUMAN Ubiquitin-like modifier-activating enzyme 7 (Ubiquitin-activating enzyme 7) (D8) (Ubiquitin-activating enzyme E1 homolog) UBA7 UBE1L UBE2 Homo sapiens (Human) DNA damage response [GO:0006974]; innate immune response [GO:0045087]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; protein modification process [GO:0036211]; protein ubiquitination [GO:0016567] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; ISG15 activating enzyme activity [GO:0019782]; ubiquitin-protein transferase activity [GO:0004842] 0.21726 0.89328 DLEPLKR 10.9487 10.6883 0 0 0 0 10.5085 0 10.5602 14.3135 13.7437 13.5356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P41227 NAA10_HUMAN N-alpha-acetyltransferase 10 (EC 2.3.1.255) (N-terminal acetyltransferase complex ARD1 subunit homolog A) (hARD1) (NatA catalytic subunit Naa10) NAA10 ARD1 ARD1A TE2 Homo sapiens (Human) "chromosome organization [GO:0051276]; internal protein amino acid acetylation [GO:0006475]; N-terminal protein amino acid acetylation [GO:0006474]; negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric [GO:2000719]; protein acetylation [GO:0006473]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; NatA complex [GO:0031415]; nucleolus [GO:0005730]; nucleus [GO:0005634] N-acetyltransferase activity [GO:0008080]; peptide alpha-N-acetyltransferase activity [GO:0004596]; peptide-glutamate-alpha-N-acetyltransferase activity [GO:1990190]; peptide-serine-alpha-N-acetyltransferase activity [GO:1990189] 0.59115 0.45477 DLSEVSETTESTDVK 0 0 0 0 0 0 0 0 9.34702 0 0 9.66153 0 0 0 0 0 0 11.4744 11.9233 11.2509 10.6661 10.7475 10.6061 12.5073 12.4995 12.3351 P41229 KDM5C_HUMAN Lysine-specific demethylase 5C (EC 1.14.11.67) (Histone demethylase JARID1C) (Jumonji/ARID domain-containing protein 1C) (Protein SmcX) (Protein Xe169) ([histone H3]-trimethyl-L-lysine(4) demethylase 5C) KDM5C DXS1272E JARID1C SMCX XE169 Homo sapiens (Human) chromatin remodeling [GO:0006338]; negative regulation of DNA-templated transcription [GO:0045892]; rhythmic process [GO:0048511] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; histone demethylase activity [GO:0032452]; histone H3K4 demethylase activity [GO:0032453]; histone H3K4me/H3K4me2/H3K4me3 demethylase activity [GO:0034647]; zinc ion binding [GO:0008270] 0.92014 -0.93134 AHLCLEAR 0 0 0 0 0 0 0 0 9.80793 0 0 0 0 0 0 0 9.40111 0 0 0 0 0 0 0 0 0 0 P41231 P2RY2_HUMAN P2Y purinoceptor 2 (P2Y2) (ATP receptor) (P2U purinoceptor 1) (P2U1) (P2U receptor 1) (Purinergic receptor) P2RY2 P2RU1 Homo sapiens (Human) blood vessel diameter maintenance [GO:0097746]; cellular response to ATP [GO:0071318]; G protein-coupled receptor signaling pathway [GO:0007186]; intracellular monoatomic ion homeostasis [GO:0006873]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of mucus secretion [GO:0070257] plasma membrane [GO:0005886] A1 adenosine receptor binding [GO:0031686]; G protein-coupled purinergic nucleotide receptor activity [GO:0045028]; G protein-coupled UTP receptor activity [GO:0045030]; signaling receptor activity [GO:0038023] 0.81307 0.22186 TLYYSFR 0 0 11.3281 0 9.25366 8.96685 10.5692 10.9748 0 0 0 0 0 10.442 10.394 0 10.4752 0 0 0 0 0 0 0 0 0 0 P41240 CSK_HUMAN Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL) CSK Homo sapiens (Human) adaptive immune response [GO:0002250]; adherens junction organization [GO:0034332]; brain development [GO:0007420]; cellular response to peptide hormone stimulus [GO:0071375]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of kinase activity [GO:0033673]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of phagocytosis [GO:0050765]; oligodendrocyte differentiation [GO:0048709]; positive regulation of MAP kinase activity [GO:0043406]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852] cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; proline-rich region binding [GO:0070064]; protein kinase A catalytic subunit binding [GO:0034236]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; protein tyrosine kinase binding [GO:1990782] 0.87755 -0.0079495 ELKLLQTIGK 0 0 10.7344 0 10.7525 0 0 9.99492 9.88646 0 11.1302 11.2242 0 10.935 0 11.0838 10.4941 10.8372 0 0 0 0 0 0 11.0066 0 0 P41247 PLPL4_HUMAN Patatin-like phospholipase domain-containing protein 4 (EC 3.1.1.3) (Calcium-independent phospholipase A2-eta) (iPLA2-eta) (EC 3.1.1.4) (Protein GS2) PNPLA4 DXS1283E GS2 Homo sapiens (Human) lipid homeostasis [GO:0055088]; triglyceride catabolic process [GO:0019433] cytoplasm [GO:0005737]; cytosol [GO:0005829]; lipid droplet [GO:0005811]; membrane [GO:0016020]; mitochondrion [GO:0005739] "acylglycerol O-acyltransferase activity [GO:0016411]; all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity [GO:0047376]; diolein transacylation activity [GO:0051265]; mono-olein transacylation activity [GO:0051264]; phospholipase A2 activity [GO:0004623]; retinyl-palmitate esterase activity [GO:0050253]; triglyceride lipase activity [GO:0004806]" 0.96354 -2.6525 FLLKENWFE 10.2817 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P41250 GARS_HUMAN Glycine--tRNA ligase (EC 6.1.1.14) (Diadenosine tetraphosphate synthetase) (Ap4A synthetase) (EC 2.7.7.-) (Glycyl-tRNA synthetase) (GlyRS) (Glycyl-tRNA synthetase 1) GARS1 GARS Homo sapiens (Human) diadenosine tetraphosphate biosynthetic process [GO:0015966]; mitochondrial glycyl-tRNA aminoacylation [GO:0070150]; tRNA aminoacylation for protein translation [GO:0006418] axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; secretory granule [GO:0030141] ATP binding [GO:0005524]; bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity [GO:0004081]; glycine-tRNA ligase activity [GO:0004820]; identical protein binding [GO:0042802]; protein dimerization activity [GO:0046983]; transferase activity [GO:0016740] 0.55773 0.54469 AKMEDTLK 0 0 0 0 0 0 0 0 0 8.75151 9.41642 9.88191 0 9.8125 0 0 0 0 0 0 0 9.39708 0 0 0 0 0 P41252 SYIC_HUMAN "Isoleucine--tRNA ligase, cytoplasmic (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IRS) (IleRS)" IARS1 IARS Homo sapiens (Human) isoleucyl-tRNA aminoacylation [GO:0006428]; osteoblast differentiation [GO:0001649]; tRNA aminoacylation for protein translation [GO:0006418] aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654] aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; GTPase binding [GO:0051020]; isoleucine-tRNA ligase activity [GO:0004822]; tRNA binding [GO:0000049] 0.96158 -2.0533 AEPDHMVLGK 0 0 0 0 0 0 12.2685 0 11.1251 0 0 0 0 0 0 0 0 0 0 0 10.4694 0 8.88053 0 8.77811 0 9.96262 P41439 FOLR3_HUMAN Folate receptor gamma (FR-gamma) (Folate receptor 3) FOLR3 Homo sapiens (Human) cell adhesion [GO:0007155]; folic acid transport [GO:0015884]; fusion of sperm to egg plasma membrane involved in single fertilization [GO:0007342]; sperm-egg recognition [GO:0035036] extracellular region [GO:0005576]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724] folic acid binding [GO:0005542]; signaling receptor activity [GO:0038023] 0.96818 -2.9215 ARTDLLNVCMNAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4548 0 0 0 0 0 0 0 0 0 0 9.19717 P41440 S19A1_HUMAN Reduced folate transporter (FOLT) (Cyclic dinucleotide:anion antiporter SLC19A1) (Folate:anion antiporter SLC19A1) (Intestinal folate carrier 1) (IFC-1) (Placental folate transporter) (Reduced folate carrier protein) (RFC) (hRFC) (Reduced folate transporter 1) (RFT-1) (Solute carrier family 19 member 1) (hSLC19A1) SLC19A1 FLOT1 RFC1 Homo sapiens (Human) cyclic-GMP-AMP transmembrane import across plasma membrane [GO:0140361]; female pregnancy [GO:0007565]; folate import across plasma membrane [GO:1904447]; folate transmembrane transport [GO:0098838]; folic acid metabolic process [GO:0046655]; folic acid transport [GO:0015884]; methotrexate transport [GO:0051958]; organic anion transport [GO:0015711]; transport across blood-brain barrier [GO:0150104]; xenobiotic transmembrane transport [GO:0006855] apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; plasma membrane [GO:0005886] "2',3'-cyclic GMP-AMP binding [GO:0061507]; antiporter activity [GO:0015297]; cyclic-GMP-AMP transmembrane transporter activity [GO:0140360]; folate:monoatomic anion antiporter activity [GO:0008518]; folic acid binding [GO:0005542]; folic acid transmembrane transporter activity [GO:0008517]; methotrexate transmembrane transporter activity [GO:0015350]; organic anion transmembrane transporter activity [GO:0008514]; xenobiotic transmembrane transporter activity [GO:0042910]" 0.82146 0.21694 CETSASELER 0 0 0 0 0 0 0 0 9.64122 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P41594 GRM5_HUMAN Metabotropic glutamate receptor 5 (mGluR5) GRM5 GPRC1E MGLUR5 Homo sapiens (Human) "calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to amyloid-beta [GO:1904646]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; learning [GO:0007612]; learning or memory [GO:0007611]; locomotory behavior [GO:0007626]; negative regulation of locomotion [GO:0040013]; phospholipase C-activating G protein-coupled glutamate receptor signaling pathway [GO:0007206]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; protein phosphorylation [GO:0006468]; regulation of DNA-templated transcription [GO:0006355]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of protein phosphorylation [GO:0001932]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of translation [GO:0006417]; regulation of translational elongation [GO:0006448]; synapse organization [GO:0050808]; trans-synaptic signaling by endocannabinoid, modulating synaptic transmission [GO:0099553]" astrocyte projection [GO:0097449]; cytoplasm [GO:0005737]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; Schaffer collateral - CA1 synapse [GO:0098685] A2A adenosine receptor binding [GO:0031687]; adenylate cyclase inhibiting G protein-coupled glutamate receptor activity [GO:0001640]; G protein-coupled receptor activity [GO:0004930]; G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential [GO:0099530]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration [GO:0099583]; protein tyrosine kinase activator activity [GO:0030296]; protein tyrosine kinase binding [GO:1990782] 0.95006 -1.4038 EGICIAHSYK 0 8.96541 0 11.0586 0 10.3231 0 0 0 0 0 0 12.6888 12.7409 12.8713 0 0 0 0 12.2994 12.0255 11.514 11.5481 11.4152 0 9.36045 0 P41595 5HT2B_HUMAN 5-hydroxytryptamine receptor 2B (5-HT-2B) (5-HT2B) (Serotonin receptor 2B) HTR2B Homo sapiens (Human) "activation of phospholipase C activity [GO:0007202]; behavior [GO:0007610]; calcium-mediated signaling [GO:0019722]; cardiac muscle hypertrophy [GO:0003300]; cellular response to temperature stimulus [GO:0071502]; cGMP-mediated signaling [GO:0019934]; chemical synaptic transmission [GO:0007268]; embryonic morphogenesis [GO:0048598]; ERK1 and ERK2 cascade [GO:0070371]; G protein-coupled receptor internalization [GO:0002031]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; G protein-coupled serotonin receptor signaling pathway [GO:0098664]; heart morphogenesis [GO:0003007]; intestine smooth muscle contraction [GO:0014827]; intracellular calcium ion homeostasis [GO:0006874]; negative regulation of apoptotic process [GO:0043066]; neural crest cell differentiation [GO:0014033]; neural crest cell migration [GO:0001755]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; phospholipase C-activating serotonin receptor signaling pathway [GO:0007208]; phosphorylation [GO:0016310]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production [GO:0001819]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphatidylinositol biosynthetic process [GO:0010513]; protein kinase C signaling [GO:0070528]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of behavior [GO:0050795]; release of sequestered calcium ion into cytosol [GO:0051209]; response to xenobiotic stimulus [GO:0009410]; vasoconstriction [GO:0042310]" cytoplasm [GO:0005737]; dendrite [GO:0030425]; G protein-coupled serotonin receptor complex [GO:0098666]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; synapse [GO:0045202] G protein-coupled serotonin receptor activity [GO:0004993]; G-protein alpha-subunit binding [GO:0001965]; Gq/11-coupled serotonin receptor activity [GO:0001587]; GTPase activator activity [GO:0005096]; neurotransmitter receptor activity [GO:0030594]; serotonin binding [GO:0051378] 0.93895 -1.3224 QIVEEQGNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0028 0 0 0 11.3731 0 P41597 CCR2_HUMAN C-C chemokine receptor type 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (Monocyte chemoattractant protein 1 receptor) (MCP-1-R) (CD antigen CD192) CCR2 CMKBR2 Homo sapiens (Human) "blood vessel remodeling [GO:0001974]; cellular defense response [GO:0006968]; cellular homeostasis [GO:0019725]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell chemotaxis [GO:0002407]; immune response [GO:0006955]; inflammatory response [GO:0006954]; inflammatory response to wounding [GO:0090594]; intracellular calcium ion homeostasis [GO:0006874]; macrophage migration [GO:1905517]; monocyte extravasation [GO:0035696]; negative regulation of adenylate cyclase activity [GO:0007194]; negative regulation of angiogenesis [GO:0016525]; negative regulation of eosinophil degranulation [GO:0043310]; negative regulation of type 2 immune response [GO:0002829]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of astrocyte chemotaxis [GO:2000464]; positive regulation of CD8-positive, alpha-beta T cell extravasation [GO:2000451]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of hematopoietic stem cell migration [GO:2000473]; positive regulation of immune complex clearance by monocytes and macrophages [GO:0090265]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of monocyte extravasation [GO:2000439]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of T-helper 1 type immune response [GO:0002827]; positive regulation of thymocyte migration [GO:2000412]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type II interferon production [GO:0032729]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of inflammatory response [GO:0050727]; regulation of T cell cytokine production [GO:0002724]; regulation of T cell differentiation [GO:0045580]; regulation of vascular endothelial growth factor production [GO:0010574]; response to wounding [GO:0009611]; sensory perception of pain [GO:0019233]; T-helper 17 cell chemotaxis [GO:0035705]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] C-C chemokine receptor activity [GO:0016493]; CCR2 chemokine receptor binding [GO:0031727]; chemokine receptor activity [GO:0004950]; identical protein binding [GO:0042802] 0.87076 0.064196 CQKEDSVYVCGPYFPR 0 8.68254 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P41743 KPCI_HUMAN Protein kinase C iota type (EC 2.7.11.13) (Atypical protein kinase C-lambda/iota) (PRKC-lambda/iota) (aPKC-lambda/iota) (nPKC-iota) PRKCI DXS1179E Homo sapiens (Human) actin filament organization [GO:0007015]; cell migration [GO:0016477]; cell-cell junction organization [GO:0045216]; cellular response to insulin stimulus [GO:0032869]; cytoskeleton organization [GO:0007010]; establishment of apical/basal cell polarity [GO:0035089]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; eye photoreceptor cell development [GO:0042462]; Golgi vesicle budding [GO:0048194]; intracellular signal transduction [GO:0035556]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron apoptotic process [GO:0043524]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of glucose import [GO:0046326]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein phosphorylation [GO:0006468]; protein targeting to membrane [GO:0006612]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; response to interleukin-1 [GO:0070555]; secretion [GO:0046903]; vesicle-mediated transport [GO:0016192] apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; brush border [GO:0005903]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; intercellular bridge [GO:0045171]; microtubule cytoskeleton [GO:0015630]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PAR polarity complex [GO:0120157]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; Schmidt-Lanterman incisure [GO:0043220]; tight junction [GO:0070160] ATP binding [GO:0005524]; calcium-dependent protein kinase C activity [GO:0004698]; metal ion binding [GO:0046872]; phospholipid binding [GO:0005543]; protein kinase activity [GO:0004672]; protein kinase C activity [GO:0004697]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.92349 -1.0171 CINCKLLVHKK 0 0 0 0 0 0 0 0 0 9.48182 11.2058 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P42025 ACTY_HUMAN Beta-centractin (Actin-related protein 1B) (ARP1B) ACTR1B CTRN2 Homo sapiens (Human) centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dynactin complex [GO:0005869]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; secretory granule lumen [GO:0034774] ATP binding [GO:0005524] 0.92447 -0.95077 AGFAGDQIPK 0 0 0 0 0 0 0 0 0 0 0 9.0334 0 0 0 0 0 0 9.1815 0 0 0 0 0 0 0 0 P42166 LAP2A_HUMAN "Lamina-associated polypeptide 2, isoform alpha (Thymopoietin isoform alpha) (TP alpha) (Thymopoietin-related peptide isoform alpha) (TPRP isoform alpha) [Cleaved into: Thymopoietin (TP) (Splenin); Thymopentin (TP5)]" TMPO LAP2 Homo sapiens (Human) chromatin [GO:0000785]; nuclear envelope [GO:0005635]; nucleus [GO:0005634] cadherin binding [GO:0045296]; DNA binding [GO:0003677]; lamin binding [GO:0005521] 0.88524 -0.37219 PEFLEDPSVLTKDK 8.49145 8.11884 0 0 9.83153 0 9.27314 11.0804 9.03386 11.1097 0 0 0 0 9.19589 0 0 0 0 0 0 0 0 0 10.412 0 0 P42224 STAT1_HUMAN Signal transducer and activator of transcription 1-alpha/beta (Transcription factor ISGF-3 components p91/p84) STAT1 Homo sapiens (Human) blood circulation [GO:0008015]; cellular response to insulin stimulus [GO:0032869]; cellular response to interferon-beta [GO:0035458]; cellular response to organic cyclic compound [GO:0071407]; cellular response to type II interferon [GO:0071346]; defense response [GO:0006952]; defense response to virus [GO:0051607]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-9-mediated signaling pathway [GO:0038113]; macrophage derived foam cell differentiation [GO:0010742]; metanephric mesenchymal cell differentiation [GO:0072162]; metanephric mesenchymal cell proliferation involved in metanephros development [GO:0072136]; negative regulation by virus of viral protein levels in host cell [GO:0046725]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003340]; negative regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072308]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of transcription by RNA polymerase II [GO:0006357]; renal tubule development [GO:0061326]; response to cAMP [GO:0051591]; response to cytokine [GO:0034097]; response to hydrogen peroxide [GO:0042542]; response to interferon-beta [GO:0035456]; response to mechanical stimulus [GO:0009612]; response to nutrient [GO:0007584]; response to peptide hormone [GO:0043434]; response to type II interferon [GO:0034341]; response to xenobiotic stimulus [GO:0009410]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; type I interferon-mediated signaling pathway [GO:0060337]; type II interferon-mediated signaling pathway [GO:0060333] axon [GO:0030424]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; ISGF3 complex [GO:0070721]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; RNA polymerase II transcription regulator complex [GO:0090575] "cadherin binding [GO:0045296]; CCR5 chemokine receptor binding [GO:0031730]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone binding [GO:0042393]; identical protein binding [GO:0042802]; nuclear receptor binding [GO:0016922]; promoter-specific chromatin binding [GO:1990841]; protein homodimerization activity [GO:0042803]; protein phosphatase 2A binding [GO:0051721]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator binding [GO:0001223]; transcription corepressor binding [GO:0001222]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin-like protein ligase binding [GO:0044389]" 0.95996 -1.7985 ERERALLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.96287 0 0 P42285 MTREX_HUMAN Exosome RNA helicase MTR4 (EC 3.6.4.13) (ATP-dependent RNA helicase DOB1) (ATP-dependent RNA helicase SKIV2L2) (Superkiller viralicidic activity 2-like 2) (TRAMP-like complex helicase) MTREX DOB1 KIAA0052 MTR4 SKIV2L2 Homo sapiens (Human) "DNA damage response [GO:0006974]; maturation of 5.8S rRNA [GO:0000460]; mRNA splicing, via spliceosome [GO:0000398]; RNA catabolic process [GO:0006401]; rRNA processing [GO:0006364]; snRNA catabolic process [GO:0016076]" catalytic step 2 spliceosome [GO:0071013]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; TRAMP complex [GO:0031499] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.63165 0.40587 LDFNTDEEK 0 0 0 0 0 0 0 0 10.0905 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P42331 RHG25_HUMAN Rho GTPase-activating protein 25 (Rho-type GTPase-activating protein 25) ARHGAP25 KIAA0053 Homo sapiens (Human) "actin filament organization [GO:0007015]; activation of GTPase activity [GO:0090630]; negative regulation of small GTPase mediated signal transduction [GO:0051058]; phagocytosis, engulfment [GO:0006911]; signal transduction [GO:0007165]" phagocytic cup [GO:0001891] GTPase activator activity [GO:0005096] 0.064516 1.3153 EKPGDWK 0 0 8.6566 8.49157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.71272 0 P42336 PK3CA_HUMAN "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.137) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide 3-kinase alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)" PIK3CA Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; adipose tissue development [GO:0060612]; angiogenesis [GO:0001525]; anoikis [GO:0043276]; cardiac muscle cell contraction [GO:0086003]; cardiac muscle contraction [GO:0060048]; cell migration [GO:0016477]; cellular response to glucose stimulus [GO:0071333]; cellular response to hydrostatic pressure [GO:0071464]; endothelial cell migration [GO:0043542]; energy homeostasis [GO:0097009]; epidermal growth factor receptor signaling pathway [GO:0007173]; glucose metabolic process [GO:0006006]; insulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028]; insulin-like growth factor receptor signaling pathway [GO:0048009]; liver development [GO:0001889]; negative regulation of actin filament depolymerization [GO:0030835]; negative regulation of anoikis [GO:2000811]; negative regulation of fibroblast apoptotic process [GO:2000270]; negative regulation of gene expression [GO:0010629]; negative regulation of macroautophagy [GO:0016242]; negative regulation of neuron apoptotic process [GO:0043524]; phagocytosis [GO:0006909]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; phosphorylation [GO:0016310]; platelet activation [GO:0030168]; positive regulation of gene expression via CpG island demethylation [GO:0044029]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of TOR signaling [GO:0032008]; protein kinase B signaling [GO:0043491]; regulation of actin filament organization [GO:0110053]; regulation of cellular respiration [GO:0043457]; regulation of genetic imprinting [GO:2000653]; regulation of multicellular organism growth [GO:0040014]; relaxation of cardiac muscle [GO:0055119]; response to activity [GO:0014823]; response to butyrate [GO:1903544]; response to dexamethasone [GO:0071548]; response to leucine [GO:0043201]; response to muscle inactivity [GO:0014870]; response to muscle stretch [GO:0035994]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculature development [GO:0001944] "cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercalated disc [GO:0014704]; lamellipodium [GO:0030027]; perinuclear region of cytoplasm [GO:0048471]; phosphatidylinositol 3-kinase complex [GO:0005942]; phosphatidylinositol 3-kinase complex, class IA [GO:0005943]; phosphatidylinositol 3-kinase complex, class IB [GO:0005944]; plasma membrane [GO:0005886]" "1-phosphatidylinositol-3-kinase activity [GO:0016303]; 1-phosphatidylinositol-4-phosphate 3-kinase activity [GO:0035005]; ATP binding [GO:0005524]; insulin receptor substrate binding [GO:0043560]; kinase activity [GO:0016301]; phosphatidylinositol 3-kinase activity [GO:0035004]; phosphatidylinositol-3,4-bisphosphate 5-kinase activity [GO:0052812]; phosphatidylinositol-4,5-bisphosphate 3-kinase activity [GO:0046934]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activator activity [GO:0043539]; protein serine/threonine kinase activity [GO:0004674]" 0.96956 -3.5038 EEFFDETRRLCDLR 0 0 0 0 0 0 0 0 10.1466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1952 0 0 P42338 PK3CB_HUMAN "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PI3-kinase subunit beta) (PI3K-beta) (PI3Kbeta) (PtdIns-3-kinase subunit beta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta) (PtdIns-3-kinase subunit p110-beta) (p110beta) (Serine/threonine protein kinase PIK3CB) (EC 2.7.11.1)" PIK3CB PIK3C1 Homo sapiens (Human) angiogenesis involved in wound healing [GO:0060055]; autophagy [GO:0006914]; cell migration [GO:0016477]; chemotaxis [GO:0006935]; embryonic cleavage [GO:0040016]; endocytosis [GO:0006897]; endothelial cell proliferation [GO:0001935]; G protein-coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intracellular calcium ion homeostasis [GO:0006874]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sprouting angiogenesis [GO:1903671]; negative regulation of vascular endothelial growth factor signaling pathway [GO:1900747]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; phosphorylation [GO:0016310]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; positive regulation of autophagy [GO:0010508]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of gene expression [GO:0010628]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Rac protein signal transduction [GO:0035022]; regulation of cell-matrix adhesion [GO:0001952]; regulation of clathrin-dependent endocytosis [GO:2000369]; response to ischemia [GO:0002931]; signal transduction [GO:0007165]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] "cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; midbody [GO:0030496]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phosphatidylinositol 3-kinase complex [GO:0005942]; phosphatidylinositol 3-kinase complex, class IA [GO:0005943]; plasma membrane [GO:0005886]" "1-phosphatidylinositol-3-kinase activity [GO:0016303]; 1-phosphatidylinositol-4-phosphate 3-kinase activity [GO:0035005]; ATP binding [GO:0005524]; insulin receptor substrate binding [GO:0043560]; kinase activity [GO:0016301]; phosphatidylinositol 3-kinase activity [GO:0035004]; phosphatidylinositol-3,4-bisphosphate 5-kinase activity [GO:0052812]; phosphatidylinositol-4,5-bisphosphate 3-kinase activity [GO:0046934]; protein serine kinase activity [GO:0106310]" 0.95439 -1.5301 GLHEFDSLK 0 0 0 0 0 9.42267 8.67937 0 0 13.7026 0 0 9.89092 10.1111 9.35986 0 0 0 0 0 0 0 0 0 0 0 0 P42345 MTOR_HUMAN Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1) MTOR FRAP FRAP1 FRAP2 RAFT1 RAPT1 Homo sapiens (Human) "'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; activation of protein kinase B activity [GO:0032148]; anoikis [GO:0043276]; behavioral response to pain [GO:0048266]; calcineurin-NFAT signaling cascade [GO:0033173]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cellular response to amino acid starvation [GO:0034198]; cellular response to amino acid stimulus [GO:0071230]; cellular response to hypoxia [GO:0071456]; cellular response to leucine [GO:0071233]; cellular response to leucine starvation [GO:1990253]; cellular response to nutrient levels [GO:0031669]; cellular response to osmotic stress [GO:0071470]; cellular response to starvation [GO:0009267]; cytoskeleton organization [GO:0007010]; DNA damage response [GO:0006974]; energy reserve metabolic process [GO:0006112]; germ cell development [GO:0007281]; heart morphogenesis [GO:0003007]; heart valve morphogenesis [GO:0003179]; inflammatory response [GO:0006954]; lysosome organization [GO:0007040]; macroautophagy [GO:0016236]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cell size [GO:0045792]; negative regulation of macroautophagy [GO:0016242]; negative regulation of protein localization to nucleus [GO:1900181]; neuronal action potential [GO:0019228]; nucleus localization [GO:0051647]; oligodendrocyte differentiation [GO:0048709]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphorylation [GO:0016310]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell growth [GO:0030307]; positive regulation of cytoplasmic translational initiation [GO:1904690]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of pentose-phosphate shunt [GO:1905857]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription by RNA polymerase III [GO:0045945]; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901838]; positive regulation of translation [GO:0045727]; positive regulation of translational initiation [GO:0045948]; positive regulation of wound healing, spreading of epidermal cells [GO:1903691]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell growth [GO:0001558]; regulation of cell size [GO:0008361]; regulation of cellular response to heat [GO:1900034]; regulation of circadian rhythm [GO:0042752]; regulation of GTPase activity [GO:0043087]; regulation of locomotor rhythm [GO:1904059]; regulation of macroautophagy [GO:0016241]; regulation of membrane permeability [GO:0090559]; regulation of myelination [GO:0031641]; regulation of osteoclast differentiation [GO:0045670]; regulation of protein kinase B signaling [GO:0051896]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to amino acid [GO:0043200]; response to heat [GO:0009408]; response to insulin [GO:0032868]; response to nutrient [GO:0007584]; response to nutrient levels [GO:0031667]; rhythmic process [GO:0048511]; ruffle organization [GO:0031529]; T-helper 1 cell lineage commitment [GO:0002296]; TOR signaling [GO:0031929]; TORC1 signaling [GO:0038202]; voluntary musculoskeletal movement [GO:0050882]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endomembrane system [GO:0012505]; endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; PML body [GO:0016605]; TORC1 complex [GO:0031931]; TORC2 complex [GO:0031932] ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; phosphoprotein binding [GO:0051219]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; ribosome binding [GO:0043022]; RNA polymerase III type 1 promoter sequence-specific DNA binding [GO:0001002]; RNA polymerase III type 2 promoter sequence-specific DNA binding [GO:0001003]; RNA polymerase III type 3 promoter sequence-specific DNA binding [GO:0001006]; TFIIIC-class transcription factor complex binding [GO:0001156]; translation regulator activity [GO:0045182] 0.92722 -1.1923 ALHYKELEFQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.6169 0 0 0 0 0 0 0 0 0 10.1119 0 P42356 PI4KA_HUMAN Phosphatidylinositol 4-kinase alpha (PI4-kinase alpha) (PI4K-alpha) (PtdIns-4-kinase alpha) (EC 2.7.1.67) (Phosphatidylinositol 4-Kinase III alpha) PI4KA PIK4 PIK4CA Homo sapiens (Human) modulation by host of viral process [GO:0044788]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphorylation [GO:0016310]; reorganization of cellular membranes to establish viral sites of replication [GO:0140754]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi-associated vesicle membrane [GO:0030660]; membrane [GO:0016020]; plasma membrane [GO:0005886] 1-phosphatidylinositol 4-kinase activity [GO:0004430]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; kinase activity [GO:0016301] 0.95994 -1.9712 APYLAKFKVK 0 0 0 11.6854 11.6218 0 0 0 0 0 0 10.2746 0 0 0 0 0 0 0 0 0 9.35696 0 0 0 0 0 P42566 EPS15_HUMAN Epidermal growth factor receptor substrate 15 (Protein Eps15) (Protein AF-1p) EPS15 AF1P Homo sapiens (Human) clathrin coat assembly [GO:0048268]; endocytic recycling [GO:0032456]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; Golgi to endosome transport [GO:0006895]; protein transport [GO:0015031]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; vesicle organization [GO:0016050]; viral entry into host cell [GO:0046718] aggresome [GO:0016235]; clathrin coat of coated pit [GO:0030132]; clathrin-coated pit [GO:0005905]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; plasma membrane [GO:0005886] cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; polyubiquitin modification-dependent protein binding [GO:0031593]; SH3 domain binding [GO:0017124] 0.92322 -1.1596 EKNNVEQDLK 0 0 0 0 0 0 0 0 0 0 9.08044 0 0 0 0 0 9.46483 0 0 10.5142 0 0 0 0 0 0 0 P42568 AF9_HUMAN Protein AF-9 (ALL1-fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3) MLLT3 AF9 YEATS3 Homo sapiens (Human) "anterior/posterior pattern specification [GO:0009952]; gene expression [GO:0010467]; hematopoietic stem cell differentiation [GO:0060218]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; regulation of chromatin organization [GO:1902275]; regulation of stem cell division [GO:2000035]; segment specification [GO:0007379]" chromosome [GO:0005694]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription elongation factor complex [GO:0008023] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; histone binding [GO:0042393]; lysine-acetylated histone binding [GO:0070577]; modification-dependent protein binding [GO:0140030]; molecular adaptor activity [GO:0060090] 0.96955 -4.6026 AGGDPNR 0 0 0 0 8.25352 0 0 0 11.6573 0 0 0 0 0 12.7118 0 0 0 0 0 0 0 0 0 0 0 0 P42574 CASP3_HUMAN Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] CASP3 CPP32 Homo sapiens (Human) anterior neural tube closure [GO:0061713]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; axonal fasciculation [GO:0007413]; B cell homeostasis [GO:0001782]; cell fate commitment [GO:0045165]; cellular response to staurosporine [GO:0072734]; DNA damage response [GO:0006974]; epithelial cell apoptotic process [GO:1904019]; erythrocyte differentiation [GO:0030218]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway [GO:0097191]; fibroblast apoptotic process [GO:0044346]; glial cell apoptotic process [GO:0034349]; heart development [GO:0007507]; hippocampus development [GO:0021766]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to osmotic stress [GO:0008627]; keratinocyte differentiation [GO:0030216]; learning or memory [GO:0007611]; leukocyte apoptotic process [GO:0071887]; luteolysis [GO:0001554]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neurotrophin TRK receptor signaling pathway [GO:0048011]; platelet formation [GO:0030220]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of apoptotic process [GO:0043065]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of pyroptosis [GO:0140639]; protein catabolic process [GO:0030163]; protein maturation [GO:0051604]; protein processing [GO:0016485]; proteolysis [GO:0006508]; pyroptosis [GO:0070269]; regulation of macroautophagy [GO:0016241]; regulation of protein stability [GO:0031647]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to cobalt ion [GO:0032025]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to tumor necrosis factor [GO:0034612]; response to UV [GO:0009411]; response to X-ray [GO:0010165]; response to xenobiotic stimulus [GO:0009410]; sensory perception of sound [GO:0007605]; striated muscle cell differentiation [GO:0051146]; T cell homeostasis [GO:0043029]; wound healing [GO:0042060] caspase complex [GO:0008303]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] aspartic-type endopeptidase activity [GO:0004190]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097199]; cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:0097200]; death receptor binding [GO:0005123]; enzyme inhibitor activity [GO:0004857]; peptidase activity [GO:0008233]; phospholipase A2 activator activity [GO:0016005]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877] 0.96132 -2.5603 SLTGKPK 0 0 9.44752 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P42658 DPP6_HUMAN Dipeptidyl aminopeptidase-like protein 6 (DPPX) (Dipeptidyl aminopeptidase-related protein) (Dipeptidyl peptidase 6) (Dipeptidyl peptidase IV-like protein) (Dipeptidyl peptidase VI) (DPP VI) DPP6 Homo sapiens (Human) protein localization to plasma membrane [GO:0072659]; proteolysis [GO:0006508]; regulation of potassium ion transmembrane transport [GO:1901379] membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076] potassium channel regulator activity [GO:0015459]; serine-type peptidase activity [GO:0008236] 0.61683 0.4173 KMFDLETNEHVK 0 0 9.91374 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6986 0 0 0 0 0 0 0 0 0 0 P42679 MATK_HUMAN Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (CSK homologous kinase) (CHK) (Hematopoietic consensus tyrosine-lacking kinase) (Protein kinase HYL) (Tyrosine-protein kinase CTK) MATK CTK HYL Homo sapiens (Human) positive regulation of cell population proliferation [GO:0008284]; protein phosphorylation [GO:0006468] cytosol [GO:0005829]; membrane [GO:0016020] ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein tyrosine kinase activity [GO:0004713] 0.88192 -0.30981 EVSEAVEKGYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.59362 0 0 0 0 0 0 0 0 0 0 P42680 TEC_HUMAN Tyrosine-protein kinase Tec (EC 2.7.10.2) TEC PSCTK4 Homo sapiens (Human) adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; regulation of platelet activation [GO:0010543]; T cell receptor signaling pathway [GO:0050852]; tissue regeneration [GO:0042246] cytoskeleton [GO:0005856]; cytosol [GO:0005829]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phospholipid binding [GO:0005543]; protein self-association [GO:0043621] 0.92723 -1.2035 ALPPAPETKKR 0 0 0 0 10.0283 0 9.87771 0 0 0 0 0 0 0 0 9.20464 0 0 0 0 0 0 0 0 0 0 0 P42681 TXK_HUMAN Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte kinase) TXK PTK4 RLK Homo sapiens (Human) activation of phospholipase C activity [GO:0007202]; adaptive immune response [GO:0002250]; integrin-mediated signaling pathway [GO:0007229]; positive regulation of cytokine production [GO:0001819]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type II interferon production [GO:0032729]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of gene expression [GO:0010468]; regulation of platelet activation [GO:0010543]; T cell receptor signaling pathway [GO:0050852]; tissue regeneration [GO:0042246] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715] 0.80026 0.23979 WSPPEVFLFNK 0 0 0 0 0 9.49133 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P42684 ABL2_HUMAN Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Abelson tyrosine-protein kinase 2) (Abelson-related gene protein) (Tyrosine-protein kinase ARG) ABL2 ABLL ARG Homo sapiens (Human) cell adhesion [GO:0007155]; cellular response to retinoic acid [GO:0071300]; exploration behavior [GO:0035640]; negative regulation of Rho protein signal transduction [GO:0035024]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of neuron projection development [GO:0010976]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of T cell migration [GO:2000406]; protein modification process [GO:0036211]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; signal transduction [GO:0007165] actin cytoskeleton [GO:0015629]; cytosol [GO:0005829] actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein kinase activity [GO:0004672]; protein tyrosine kinase activity [GO:0004713] 0.87084 0.063838 TDITMKHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5946 0 0 0 0 0 0 0 0 0 0 0 P42685 FRK_HUMAN Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5) FRK PTK5 RAK Homo sapiens (Human) cell differentiation [GO:0030154]; innate immune response [GO:0045087]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] azurophil granule lumen [GO:0035578]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; specific granule lumen [GO:0035580] ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102] 0.84101 0.14331 NVLVGEHNIYK 0 0 14.6873 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P42694 HELZ_HUMAN Probable helicase with zinc finger domain (EC 3.6.4.-) (Down-regulated in human cancers protein) HELZ DRHC KIAA0054 Homo sapiens (Human) ncRNA-mediated post-transcriptional gene silencing [GO:0035194] cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; P granule [GO:0043186] ATP binding [GO:0005524]; helicase activity [GO:0004386]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; RNA binding [GO:0003723] 0.92272 -1.0838 EKVYEATIEEK 0 0 11.6843 0 0 11.1003 0 0 0 10.5554 10.0126 0 0 9.15102 0 11.6883 11.7936 11.8338 0 0 0 0 0 0 0 11.3533 10.8102 P42695 CNDD3_HUMAN Condensin-2 complex subunit D3 (Non-SMC condensin II complex subunit D3) (hCAP-D3) NCAPD3 CAPD3 KIAA0056 Homo sapiens (Human) cell division [GO:0051301]; meiotic chromosome condensation [GO:0010032]; mitotic chromosome condensation [GO:0007076]; positive regulation of chromosome condensation [GO:1905821]; positive regulation of chromosome segregation [GO:0051984]; positive regulation of chromosome separation [GO:1905820] "condensed chromosome, centromeric region [GO:0000779]; condensed nuclear chromosome [GO:0000794]; condensin complex [GO:0000796]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; pericentric heterochromatin [GO:0005721]" histone binding [GO:0042393]; methylated histone binding [GO:0035064] 0.96219 -2.6133 EIKLLAMR 0 0 0 0 0 0 10.996 10.9946 0 0 0 10.4389 0 0 8.44704 9.6151 0 0 9.76744 0 0 0 9.37675 0 10.5461 0 0 P42701 I12R1_HUMAN Interleukin-12 receptor subunit beta-1 (IL-12 receptor subunit beta-1) (IL-12R subunit beta-1) (IL-12R-beta-1) (IL-12RB1) (IL-12 receptor beta component) (CD antigen CD212) IL12RB1 IL12R IL12RB Homo sapiens (Human) cellular response to type II interferon [GO:0071346]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of memory T cell differentiation [GO:0043382]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 type immune response [GO:0002827]; positive regulation of T-helper 17 cell lineage commitment [GO:2000330]; positive regulation of T-helper 17 type immune response [GO:2000318]; positive regulation of type II interferon production [GO:0032729]; signal transduction [GO:0007165] external side of plasma membrane [GO:0009897]; interleukin-12 receptor complex [GO:0042022]; interleukin-23 receptor complex [GO:0072536]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896] 0.79974 0.23976 QLGSQGSSWSK 0 0 0 0 0 0 0 9.61261 0 0 0 0 0 0 0 0 0 9.70129 0 0 0 0 0 0 0 0 0 P42702 LIFR_HUMAN Leukemia inhibitory factor receptor (LIF receptor) (LIF-R) (CD antigen CD118) LIFR Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; leukemia inhibitory factor signaling pathway [GO:0048861]; oncostatin-M-mediated signaling pathway [GO:0038165]; positive regulation of cell population proliferation [GO:0008284]; response to cytokine [GO:0034097] external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] ciliary neurotrophic factor receptor binding [GO:0005127]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; leukemia inhibitory factor receptor activity [GO:0004923] 0.92278 -1.0824 NITDISQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.82903 0 0 0 0 0 0 P42704 LPPRC_HUMAN "Leucine-rich PPR motif-containing protein, mitochondrial (130 kDa leucine-rich protein) (LRP 130) (GP130)" LRPPRC LRP130 Homo sapiens (Human) mitochondrial RNA catabolic process [GO:0000957]; mitochondrion transport along microtubule [GO:0047497]; mRNA transport [GO:0051028]; negative regulation of mitochondrial RNA catabolic process [GO:0000961]; regulation of mitochondrial translation [GO:0070129] condensed nuclear chromosome [GO:0000794]; cytoskeleton [GO:0005856]; membrane [GO:0016020]; microtubule [GO:0005874]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; nuclear inner membrane [GO:0005637]; nuclear outer membrane [GO:0005640]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribonucleoprotein complex [GO:1990904] beta-tubulin binding [GO:0048487]; microtubule binding [GO:0008017]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; ubiquitin protein ligase binding [GO:0031625] 0.96576 -2.7197 EQNIVFNAETYSNLIK 10.1966 0 0 0 0 0 0 0 0 0 0 0 9.75511 0 0 0 0 10.3924 0 0 0 0 0 0 0 0 0 P42765 THIM_HUMAN "3-ketoacyl-CoA thiolase, mitochondrial (EC 2.3.1.16) (Acetyl-CoA acetyltransferase) (EC 2.3.1.9) (Acetyl-CoA acyltransferase) (Acyl-CoA hydrolase, mitochondrial) (EC 3.1.2.-, EC 3.1.2.1, EC 3.1.2.2) (Beta-ketothiolase) (Mitochondrial 3-oxoacyl-CoA thiolase) (T1)" ACAA2 Homo sapiens (Human) cellular response to hypoxia [GO:0071456]; cholesterol biosynthetic process [GO:0006695]; fatty acid beta-oxidation [GO:0006635]; negative regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902109]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] acetyl-CoA C-acetyltransferase activity [GO:0003985]; acetyl-CoA C-acyltransferase activity [GO:0003988]; acetyl-CoA hydrolase activity [GO:0003986]; acyl-CoA hydrolase activity [GO:0047617]; myristoyl-CoA hydrolase activity [GO:0102991]; palmitoyl-CoA hydrolase activity [GO:0016290]; RNA binding [GO:0003723] 0.83321 0.19884 YALQSQQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.94968 0 0 0 0 P42766 RL35_HUMAN Large ribosomal subunit protein uL29 (60S ribosomal protein L35) RPL35 Homo sapiens (Human) "cytoplasmic translation [GO:0002181]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; translation [GO:0006412]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; membrane [GO:0016020]; nucleolus [GO:0005730] mRNA binding [GO:0003729]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.81584 0.22134 VLTVINQTQK 0 0 0 0 0 0 0 0 11.1558 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P42771 CDN2A_HUMAN Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A) CDKN2A CDKN2 MTS1 Homo sapiens (Human) cell cycle [GO:0007049]; cellular senescence [GO:0090398]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of phosphorylation [GO:0042326]; positive regulation of macrophage apoptotic process [GO:2000111]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; Ras protein signal transduction [GO:0007265]; regulation of cell cycle [GO:0051726]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; replicative senescence [GO:0090399] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; senescence-associated heterochromatin focus [GO:0035985] cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; NF-kappaB binding [GO:0051059]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723] 0.67682 0.39371 AAAGGTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.66306 P42772 CDN2B_HUMAN Cyclin-dependent kinase 4 inhibitor B (Multiple tumor suppressor 2) (MTS-2) (p14-INK4b) (p15-INK4b) (p15INK4B) CDKN2B MTS2 Homo sapiens (Human) aging [GO:0007568]; cell cycle [GO:0007049]; cellular response to extracellular stimulus [GO:0031668]; cellular response to nutrient [GO:0031670]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular senescence [GO:0090398]; liver development [GO:0001889]; megakaryocyte differentiation [GO:0030219]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of phosphorylation [GO:0042326]; positive regulation of epithelial cell differentiation [GO:0030858]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; response to cytokine [GO:0034097]; response to organic cyclic compound [GO:0014070]; spleen development [GO:0048536] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; protein kinase binding [GO:0019901] 0.80172 0.23941 AIQVMMMGSAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0612 0 0 0 0 0 0 0 P42785 PCP_HUMAN Lysosomal Pro-X carboxypeptidase (EC 3.4.16.2) (Angiotensinase C) (Lysosomal carboxypeptidase C) (Proline carboxypeptidase) (Prolylcarboxypeptidase) (PRCP) PRCP PCP Homo sapiens (Human) angiogenesis involved in wound healing [GO:0060055]; energy homeostasis [GO:0097009]; glucose homeostasis [GO:0042593]; negative regulation of systemic arterial blood pressure [GO:0003085]; plasma kallikrein-kinin cascade [GO:0002353]; proteolysis [GO:0006508]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of thyroid hormone mediated signaling pathway [GO:0002155] azurophil granule membrane [GO:0035577]; basal part of cell [GO:0045178]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886] dipeptidyl-peptidase activity [GO:0008239]; serine-type carboxypeptidase activity [GO:0004185] 0.95238 -1.3887 IVTTDFRKSGPHCSESIHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1828 0 0 0 0 P42830 CXCL5_HUMAN C-X-C motif chemokine 5 (ENA-78(1-78)) (Epithelial-derived neutrophil-activating protein 78) (Neutrophil-activating peptide ENA-78) (Small-inducible cytokine B5) [Cleaved into: ENA-78(8-78); ENA-78(9-78)] CXCL5 ENA78 SCYB5 Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell-cell signaling [GO:0007267]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; inflammatory response [GO:0006954]; neutrophil chemotaxis [GO:0030593]; positive regulation of cell population proliferation [GO:0008284]; signal transduction [GO:0007165] extracellular region [GO:0005576]; extracellular space [GO:0005615] chemokine activity [GO:0008009]; CXCR chemokine receptor binding [GO:0045236]; identical protein binding [GO:0042802] 0.78177 0.26111 EICLDPEAPFLK 9.04502 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P42858 HD_HUMAN "Huntingtin (Huntington disease protein) (HD protein) [Cleaved into: Huntingtin, myristoylated N-terminal fragment]" HTT HD IT15 Homo sapiens (Human) "apoptotic process [GO:0006915]; establishment of mitotic spindle orientation [GO:0000132]; Golgi organization [GO:0007030]; microtubule-based transport [GO:0099111]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of aggrephagy [GO:1905337]; positive regulation of apoptotic process [GO:0043065]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of cilium assembly [GO:0045724]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; positive regulation of lipophagy [GO:1904504]; protein destabilization [GO:0031648]; regulation of CAMKK-AMPK signaling cascade [GO:1905289]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of phosphoprotein phosphatase activity [GO:0043666]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; vesicle transport along microtubule [GO:0047496]; vocal learning [GO:0042297]" autophagosome [GO:0005776]; axon [GO:0030424]; centriole [GO:0005814]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; late endosome [GO:0005770]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; protein-containing complex [GO:0032991] beta-tubulin binding [GO:0048487]; dynactin binding [GO:0034452]; dynein intermediate chain binding [GO:0045505]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; p53 binding [GO:0002039]; profilin binding [GO:0005522]; transmembrane transporter binding [GO:0044325] 0.007772 2.0404 ALALSCVGAAVALHPESFFSK 0 0 0 8.86851 0 0 0 0 0 0 0 12.1156 11.5353 11.4428 11.3063 0 0 0 0 10.0334 0 0 0 0 10.3029 0 0 P42892 ECE1_HUMAN Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71) ECE1 Homo sapiens (Human) axonogenesis involved in innervation [GO:0060385]; bradykinin catabolic process [GO:0010815]; calcitonin catabolic process [GO:0010816]; ear development [GO:0043583]; embryonic digit morphogenesis [GO:0042733]; embryonic heart tube development [GO:0035050]; endothelin maturation [GO:0034959]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; hormone catabolic process [GO:0042447]; peptide hormone processing [GO:0016486]; pharyngeal system development [GO:0060037]; positive regulation of receptor recycling [GO:0001921]; protein processing [GO:0016485]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of vasoconstriction [GO:0019229]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; substance P catabolic process [GO:0010814]; sympathetic neuron axon guidance [GO:0097492] early endosome [GO:0005769]; endosome [GO:0005768]; endosome membrane [GO:0010008]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; Weibel-Palade body [GO:0033093] endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; peptide hormone binding [GO:0017046]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270] 0.96947 -4.0997 AYQNWVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.56127 0 0 0 0 0 P43003 EAA1_HUMAN Excitatory amino acid transporter 1 (Sodium-dependent glutamate/aspartate transporter 1) (GLAST-1) (Solute carrier family 1 member 3) SLC1A3 EAAT1 GLAST GLAST1 Homo sapiens (Human) auditory behavior [GO:0031223]; cell morphogenesis involved in neuron differentiation [GO:0048667]; cellular response to cocaine [GO:0071314]; chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; cranial nerve development [GO:0021545]; D-aspartate import across plasma membrane [GO:0070779]; gamma-aminobutyric acid biosynthetic process [GO:0009449]; intracellular sodium ion homeostasis [GO:0006883]; L-aspartate import across plasma membrane [GO:0140009]; L-glutamate import [GO:0051938]; L-glutamate import across plasma membrane [GO:0098712]; L-glutamate transmembrane transport [GO:0015813]; monoatomic ion transport [GO:0006811]; neuromuscular process controlling balance [GO:0050885]; neurotransmitter transport [GO:0006836]; neurotransmitter uptake [GO:0001504]; positive regulation of synaptic transmission [GO:0050806]; potassium ion transmembrane transport [GO:0071805]; response to antibiotic [GO:0046677]; response to light stimulus [GO:0009416]; response to wounding [GO:0009611]; response to xenobiotic stimulus [GO:0009410]; sensory perception of sound [GO:0007605]; transepithelial transport [GO:0070633]; transport across blood-brain barrier [GO:0150104] basal plasma membrane [GO:0009925]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; membrane [GO:0016020]; membrane protein complex [GO:0098796]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202] glutamate binding [GO:0016595]; glutamate:sodium symporter activity [GO:0015501]; high-affinity L-glutamate transmembrane transporter activity [GO:0005314]; L-glutamate transmembrane transporter activity [GO:0005313]; metal ion binding [GO:0046872]; neutral L-amino acid transmembrane transporter activity [GO:0015175] 0.72753 0.35238 KVQNITKEDVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.17463 0 0 0 0 0 0 0 0 0 0 0 0 P43034 LIS1_HUMAN Platelet-activating factor acetylhydrolase IB subunit beta (Lissencephaly-1 protein) (LIS-1) (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) PAFAH1B1 LIS1 MDCR MDS PAFAHA Homo sapiens (Human) acrosome assembly [GO:0001675]; actin cytoskeleton organization [GO:0030036]; adult locomotory behavior [GO:0008344]; ameboidal-type cell migration [GO:0001667]; auditory receptor cell development [GO:0060117]; brain morphogenesis [GO:0048854]; cerebral cortex development [GO:0021987]; cerebral cortex neuron differentiation [GO:0021895]; chemical synaptic transmission [GO:0007268]; cochlea development [GO:0090102]; corpus callosum morphogenesis [GO:0021540]; cortical microtubule organization [GO:0043622]; establishment of centrosome localization [GO:0051660]; establishment of mitotic spindle orientation [GO:0000132]; establishment of planar polarity of embryonic epithelium [GO:0042249]; germ cell development [GO:0007281]; hippocampus development [GO:0021766]; interneuron migration [GO:1904936]; JNK cascade [GO:0007254]; layer formation in cerebral cortex [GO:0021819]; learning or memory [GO:0007611]; lipid catabolic process [GO:0016042]; maintenance of centrosome location [GO:0051661]; microtubule cytoskeleton organization [GO:0000226]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; microtubule organizing center organization [GO:0031023]; microtubule sliding [GO:0051012]; microtubule-based process [GO:0007017]; modulation of chemical synaptic transmission [GO:0050804]; myeloid leukocyte migration [GO:0097529]; negative regulation of JNK cascade [GO:0046329]; negative regulation of neuron projection development [GO:0010977]; neuroblast proliferation [GO:0007405]; neuromuscular process controlling balance [GO:0050885]; neuron migration [GO:0001764]; nuclear membrane disassembly [GO:0051081]; nuclear migration [GO:0007097]; osteoclast development [GO:0036035]; platelet activating factor metabolic process [GO:0046469]; positive regulation of axon extension [GO:0045773]; positive regulation of cytokine-mediated signaling pathway [GO:0001961]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of embryonic development [GO:0040019]; positive regulation of mitotic cell cycle [GO:0045931]; protein secretion [GO:0009306]; radial glia-guided pyramidal neuron migration [GO:0140650]; reelin-mediated signaling pathway [GO:0038026]; regulation of GTPase activity [GO:0043087]; regulation of microtubule cytoskeleton organization [GO:0070507]; retrograde axonal transport [GO:0008090]; stem cell division [GO:0017145]; transmission of nerve impulse [GO:0019226]; vesicle transport along microtubule [GO:0047496] 1-alkyl-2-acetylglycerophosphocholine esterase complex [GO:0008247]; astral microtubule [GO:0000235]; axon cytoplasm [GO:1904115]; cell cortex [GO:0005938]; cell leading edge [GO:0031252]; central region of growth cone [GO:0090724]; centrosome [GO:0005813]; cytoplasmic microtubule [GO:0005881]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; kinesin complex [GO:0005871]; kinetochore [GO:0000776]; microtubule associated complex [GO:0005875]; motile cilium [GO:0031514]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; Schaffer collateral - CA1 synapse [GO:0098685]; stereocilium [GO:0032420] dynactin binding [GO:0034452]; dynein complex binding [GO:0070840]; dynein intermediate chain binding [GO:0045505]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; phospholipase binding [GO:0043274]; phosphoprotein binding [GO:0051219]; protein heterodimerization activity [GO:0046982] 0.90627 -0.71956 LLASCSADMTIK 0 0 0 0 0 0 0 0 0 0 9.99591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5973 P43121 MUC18_HUMAN Cell surface glycoprotein MUC18 (Cell surface glycoprotein P1H12) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (Melanoma-associated antigen MUC18) (S-endo 1 endothelial-associated antigen) (CD antigen CD146) MCAM MUC18 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; glomerular filtration [GO:0003094]; positive regulation of cell migration [GO:0030335]; vascular wound healing [GO:0061042] external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; plasma membrane [GO:0005886] 0.96125 -2.5603 EAGGGYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.46508 0 0 0 0 0 0 0 0 0 0 0 P43146 DCC_HUMAN Netrin receptor DCC (Colorectal cancer suppressor) (Immunoglobulin superfamily DCC subclass member 1) (Tumor suppressor protein DCC) DCC IGDCC1 Homo sapiens (Human) anterior/posterior axon guidance [GO:0033564]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cell-cell adhesion [GO:0098609]; dorsal/ventral axon guidance [GO:0033563]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendrite development [GO:2000171]; negative regulation of neuron projection development [GO:0010977]; neuron migration [GO:0001764]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; spinal cord ventral commissure morphogenesis [GO:0021965] axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; Schaffer collateral - CA1 synapse [GO:0098685] transmembrane signaling receptor activity [GO:0004888] 0.60995 0.43159 ATHSAGK 8.55021 0 0 0 0 0 0 0 0 0 0 0 0 0 9.84504 0 0 0 0 0 0 0 0 0 0 0 0 P43155 CACP_HUMAN Carnitine O-acetyltransferase (Carnitine acetylase) (EC 2.3.1.137) (EC 2.3.1.7) (Carnitine acetyltransferase) (CAT) (CrAT) CRAT CAT1 Homo sapiens (Human) "carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; medium-chain fatty acid metabolic process [GO:0051791]; short-chain fatty acid metabolic process [GO:0046459]" cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777] acyl-CoA oxidase activity [GO:0003997]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine O-octanoyltransferase activity [GO:0008458] 0.95417 -1.5134 NSWAKAYNTLIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.67377 0 0 0 P43166 CAH7_HUMAN Carbonic anhydrase 7 (EC 4.2.1.1) (Carbonate dehydratase VII) (Carbonic anhydrase VII) (CA-VII) CA7 Homo sapiens (Human) "neuron cellular homeostasis [GO:0070050]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]" cytoplasm [GO:0005737]; cytosol [GO:0005829] carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270] 0.84282 0.14094 EPICISERQMGK 0 0 0 9.15972 0 0 0 0 0 0 0 0 0 0 0 0 10.9702 0 0 0 0 0 0 0 0 0 0 P43220 GLP1R_HUMAN Glucagon-like peptide 1 receptor (GLP-1 receptor) (GLP-1-R) (GLP-1R) GLP1R Homo sapiens (Human) "activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP-mediated signaling [GO:0019933]; cell surface receptor signaling pathway [GO:0007166]; hormone secretion [GO:0046879]; learning or memory [GO:0007611]; negative regulation of blood pressure [GO:0045776]; positive regulation of blood pressure [GO:0045777]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; post-translational protein targeting to membrane, translocation [GO:0031204]; regulation of heart contraction [GO:0008016]; response to psychosocial stress [GO:1990911]" membrane [GO:0016020]; plasma membrane [GO:0005886] glucagon receptor activity [GO:0004967]; glucagon-like peptide 1 receptor activity [GO:0044508]; peptide hormone binding [GO:0017046]; transmembrane signaling receptor activity [GO:0004888] 0.89834 -0.68143 ALSVFIK 0 0 16.2821 0 0 0 0 0 0 0 0 0 12.3968 0 9.92351 0 0 12.7093 0 0 0 0 0 0 0 0 0 P43235 CATK_HUMAN Cathepsin K (EC 3.4.22.38) (Cathepsin O) (Cathepsin O2) (Cathepsin X) CTSK CTSO CTSO2 Homo sapiens (Human) autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to zinc ion starvation [GO:0034224]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; intramembranous ossification [GO:0001957]; mononuclear cell differentiation [GO:1903131]; negative regulation of cartilage development [GO:0061037]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of peptidase activity [GO:0010952]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; response to ethanol [GO:0045471]; response to insulin [GO:0032868]; response to organic cyclic compound [GO:0014070]; thyroid hormone generation [GO:0006590] apical plasma membrane [GO:0016324]; endolysosome lumen [GO:0036021]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654] collagen binding [GO:0005518]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]; serine-type endopeptidase activity [GO:0004252] 0.88291 -0.04037 GNKHWIIK 11.3005 10.9815 11.1152 0 0 0 10.6802 10.6717 10.6306 0 0 10.1286 0 0 0 0 0 0 0 0 0 0 0 0 0 9.89931 0 P43243 MATR3_HUMAN Matrin-3 MATR3 KIAA0723 Homo sapiens (Human) activation of innate immune response [GO:0002218]; blastocyst formation [GO:0001825]; heart valve development [GO:0003170]; innate immune response [GO:0045087]; post-transcriptional regulation of gene expression [GO:0010608]; ventricular septum development [GO:0003281] membrane [GO:0016020]; nuclear inner membrane [GO:0005637]; nuclear matrix [GO:0016363]; nucleus [GO:0005634] identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270] 0.95322 -1.5005 DSQGHGR 0 0 0 0 0 0 0 0 0 0 0 8.49366 0 0 8.91477 0 0 0 0 0 10.6326 9.4765 0 9.49319 0 9.82066 0 P43250 GRK6_HUMAN G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK6) GRK6 GPRK6 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; protein phosphorylation [GO:0006468]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; regulation of signal transduction [GO:0009966]; Wnt signaling pathway [GO:0016055] cytoplasm [GO:0005737]; membrane [GO:0016020]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; beta-adrenergic receptor kinase activity [GO:0047696]; G protein-coupled receptor kinase activity [GO:0004703] 0.95227 -1.389 EGGGGNR 0 0 0 0 0 0 0 0 0 0 8.85842 11.1837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.52845 P43251 BTD_HUMAN Biotinidase (Biotinase) (EC 3.5.1.12) BTD Homo sapiens (Human) biotin metabolic process [GO:0006768]; central nervous system development [GO:0007417] extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759] biotinidase activity [GO:0047708] 0.80801 0.22916 FVVCIMSGAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3733 0 0 0 0 P43304 GPDM_HUMAN "Glycerol-3-phosphate dehydrogenase, mitochondrial (GPD-M) (GPDH-M) (EC 1.1.5.3) (mitohondrial glycerophosphate dehydrogenase gene) (mGDH) (mtGPD)" GPD2 Homo sapiens (Human) glycerol catabolic process [GO:0019563]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerophosphate shuttle [GO:0006127] glycerol-3-phosphate dehydrogenase complex [GO:0009331]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] calcium ion binding [GO:0005509]; glycerol-3-phosphate dehydrogenase (quinone) activity [GO:0004368]; sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity [GO:0052591] 0.88422 -0.14162 ALEHFPMLQKDK 9.86596 0 0 0 0 0 0 0 0 0 0 0 0 12.1103 0 0 0 0 0 0 0 0 0 0 0 0 12.7665 P43307 SSRA_HUMAN Translocon-associated protein subunit alpha (TRAP-alpha) (Signal sequence receptor subunit alpha) (SSR-alpha) SSR1 TRAPA PSEC0262 Homo sapiens (Human) cotranslational protein targeting to membrane [GO:0006613]; positive regulation of cell population proliferation [GO:0008284] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] 0.45138 0.64146 FLVGFTNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.16697 0 0 0 0 0 10.7908 10.0102 10.0157 P43320 CRBB2_HUMAN Beta-crystallin B2 (Beta-B2 crystallin) (Beta-crystallin Bp) CRYBB2 CRYB2 CRYB2A Homo sapiens (Human) lens development in camera-type eye [GO:0002088]; response to stimulus [GO:0050896]; visual perception [GO:0007601] identical protein binding [GO:0042802]; structural constituent of eye lens [GO:0005212]; structural molecule activity [GO:0005198] 0.67234 0.39371 GAFHPSN 0 0 0 0 0 0 0 8.10575 0 8.62374 8.66228 8.81622 0 0 0 0 0 0 8.71908 0 8.5635 0 0 0 0 0 0 P43351 RAD52_HUMAN DNA repair protein RAD52 homolog RAD52 Homo sapiens (Human) cellular response to oxidative stress [GO:0034599]; DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via single-strand annealing [GO:0045002]; mitotic recombination [GO:0006312]; regulation of nucleotide-excision repair [GO:2000819] nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993] DNA binding [GO:0003677]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697] 0.65023 0.39598 MAGGGQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.96177 0 P43358 MAGA4_HUMAN Melanoma-associated antigen 4 (Cancer/testis antigen 1.4) (CT1.4) (MAGE-4 antigen) (MAGE-41 antigen) (MAGE-X2 antigen) MAGEA4 MAGE4 Homo sapiens (Human) negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell cycle [GO:0045787] nucleus [GO:0005634] histone deacetylase binding [GO:0042826] 0.90755 -0.73645 EALSNKVDELAHFLLR 11.1638 11.0068 10.8062 10.5624 0 0 9.93369 10.1757 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P43364 MAGAB_HUMAN Melanoma-associated antigen 11 (Cancer/testis antigen 1.11) (CT1.11) (MAGE-11 antigen) MAGEA11 MAGE11 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] histone deacetylase binding [GO:0042826] 0.96276 -2.5279 SPRRTQR 0 0 0 0 0 0 0 0 0 0 0 0 10.9766 0 8.73393 0 0 0 0 0 0 0 0 0 0 0 0 P43378 PTN9_HUMAN Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase MEG2) PTPN9 Homo sapiens (Human) negative regulation of neuron projection development [GO:0010977]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein dephosphorylation [GO:0006470] cytoplasm [GO:0005737]; neuron projection terminus [GO:0044306]; nucleoplasm [GO:0005654] non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; protein tyrosine phosphatase activity [GO:0004725] 0.9457 -1.343 AIELFHSYRETRR 0 0 0 10.7003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P43405 KSYK_HUMAN Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk) SYK Homo sapiens (Human) adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; beta selection [GO:0043366]; blood vessel morphogenesis [GO:0048514]; calcium-mediated signaling [GO:0019722]; cell activation [GO:0001775]; cell differentiation [GO:0030154]; cellular response to lectin [GO:1990858]; cellular response to lipid [GO:0071396]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to molecule of fungal origin [GO:0071226]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; gamma-delta T cell differentiation [GO:0042492]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; interleukin-3-mediated signaling pathway [GO:0038156]; intracellular signal transduction [GO:0035556]; leukocyte activation involved in immune response [GO:0002366]; leukocyte cell-cell adhesion [GO:0007159]; leukotriene biosynthetic process [GO:0019370]; lymph vessel development [GO:0001945]; macrophage activation involved in immune response [GO:0002281]; mast cell degranulation [GO:0043303]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; neutrophil activation involved in immune response [GO:0002283]; neutrophil chemotaxis [GO:0030593]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of bone resorption [GO:0045780]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of gamma-delta T cell differentiation [GO:0045588]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-3 production [GO:0032752]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of killing of cells of another organism [GO:0051712]; positive regulation of mast cell cytokine production [GO:0032765]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein-containing complex assembly [GO:0031334]; positive regulation of receptor internalization [GO:0002092]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon production [GO:0032481]; protein autophosphorylation [GO:0046777]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; receptor internalization [GO:0031623]; regulation of arachidonic acid secretion [GO:0090237]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of neutrophil degranulation [GO:0043313]; regulation of phagocytosis [GO:0050764]; regulation of platelet activation [GO:0010543]; regulation of platelet aggregation [GO:0090330]; regulation of superoxide anion generation [GO:0032928]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; serotonin secretion by platelet [GO:0002554]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] B cell receptor complex [GO:0019815]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early phagosome [GO:0032009]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; T cell receptor complex [GO:0042101] ATP binding [GO:0005524]; integrin binding [GO:0005178]; interleukin-15 receptor binding [GO:0016170]; kinase activity [GO:0016301]; molecular function activator activity [GO:0140677]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatase binding [GO:0019902]; phospholipase binding [GO:0043274]; phosphotyrosine residue binding [GO:0001784]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; signaling receptor binding [GO:0005102]; Toll-like receptor binding [GO:0035325] 0.92716 -1.1939 ENLIREYVK 0 0 0 0 0 0 18.2556 0 0 18.1676 0 0 0 17.0437 17.0938 0 0 17.7095 0 0 0 0 0 0 0 0 0 P43487 RANG_HUMAN Ran-specific GTPase-activating protein (Ran-binding protein 1) (RanBP1) RANBP1 Homo sapiens (Human) nucleocytoplasmic transport [GO:0006913]; positive regulation of mitotic centrosome separation [GO:0046604]; signal transduction [GO:0007165] centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleus [GO:0005634] cadherin binding [GO:0045296]; GDP-dissociation inhibitor activity [GO:0005092]; GTPase activator activity [GO:0005096]; small GTPase binding [GO:0031267] 0.33546 0.77309 FLNAENAQK 0 0 0 0 0 0 10.0139 0 9.87266 0 9.46938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P43490 NAMPT_HUMAN Nicotinamide phosphoribosyltransferase (NAmPRTase) (Nampt) (EC 2.4.2.12) (Pre-B-cell colony-enhancing factor 1) (Pre-B cell-enhancing factor) (Visfatin) NAMPT PBEF PBEF1 Homo sapiens (Human) cell-cell signaling [GO:0007267]; circadian regulation of gene expression [GO:0032922]; NAD biosynthesis via nicotinamide riboside salvage pathway [GO:0034356]; NAD biosynthetic process [GO:0009435]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of transcription by RNA polymerase II [GO:0045944]; signal transduction [GO:0007165] cell junction [GO:0030054]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nuclear speck [GO:0016607] cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; nicotinamide phosphoribosyltransferase activity [GO:0047280] 0 7.3812 AVPEGFVIPR 8.87157 8.66878 0 0 9.12619 8.47683 8.36741 0 0 0 0 0 0 0 0 0 0 0 0 11.5562 0 0 0 0 0 0 0 P43652 AFAM_HUMAN Afamin (Alpha-albumin) (Alpha-Alb) AFM ALB2 ALBA Homo sapiens (Human) protein stabilization [GO:0050821]; protein transport within extracellular region [GO:0071693]; vitamin transport [GO:0051180] blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615] vitamin E binding [GO:0008431] 0.95504 -1.5646 CMADKTLPECSK 12.5704 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.31102 0 0 0 0 0 0 P43657 LPAR6_HUMAN Lysophosphatidic acid receptor 6 (LPA receptor 6) (LPA-6) (Oleoyl-L-alpha-lysophosphatidic acid receptor) (P2Y purinoceptor 5) (P2Y5) (Purinergic receptor 5) (RB intron encoded G-protein coupled receptor) LPAR6 P2RY5 Homo sapiens (Human) blastocyst hatching [GO:0001835]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of Rho protein signal transduction [GO:0035025] plasma membrane [GO:0005886] lysophosphatidic acid receptor activity [GO:0070915] 0.94647 -1.352 INKTKVLK 0 0 0 0 0 0 0 9.40608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P45379 TNNT2_HUMAN "Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT)" TNNT2 Homo sapiens (Human) actin crosslink formation [GO:0051764]; cardiac muscle contraction [GO:0060048]; muscle filament sliding [GO:0030049]; negative regulation of ATP-dependent activity [GO:0032780]; positive regulation of ATP-dependent activity [GO:0032781]; regulation of heart contraction [GO:0008016]; regulation of muscle filament sliding speed [GO:0032972]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; ventricular cardiac muscle tissue morphogenesis [GO:0055010] cardiac myofibril [GO:0097512]; cardiac Troponin complex [GO:1990584]; cytosol [GO:0005829]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; troponin complex [GO:0005861] actin binding [GO:0003779]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; protein-macromolecule adaptor activity [GO:0030674]; tropomyosin binding [GO:0005523]; troponin C binding [GO:0030172]; troponin I binding [GO:0031013] 0.16447 0.98566 KVLAIDHLNEDQLR 0 11.45 0 0 0 0 0 0 0 9.35843 9.95184 9.76913 0 0 0 12.5812 8.57539 0 8.12939 0 0 0 0 0 0 0 0 P45381 ACY2_HUMAN Aspartoacylase (EC 3.5.1.15) (Aminoacylase-2) (ACY-2) ASPA ACY2 ASP Homo sapiens (Human) acetate metabolic process [GO:0006083]; aspartate catabolic process [GO:0006533]; central nervous system myelination [GO:0022010]; positive regulation of oligodendrocyte differentiation [GO:0048714] cytosol [GO:0005829]; nucleus [GO:0005634] "aminoacylase activity [GO:0004046]; aspartoacylase activity [GO:0019807]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]" 0.9215 -1.1383 CTRYIDCDLNR 0 0 0 0 0 0 0 0 11.2382 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2622 0 0 0 0 P45452 MMP13_HUMAN Collagenase 3 (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13) MMP13 Homo sapiens (Human) bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645] extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270] 0.1664 0.97391 ISELGLPK 0 0 0 0 0 11.5553 0 0 8.73867 0 0 9.08969 0 0 0 0 0 0 0 0 0 10.0565 0 0 0 10.1812 0 P45844 ABCG1_HUMAN ATP-binding cassette sub-family G member 1 (EC 7.6.2.-) (ATP-binding cassette transporter 8) (White protein homolog) ABCG1 ABC8 WHT1 Homo sapiens (Human) amyloid precursor protein catabolic process [GO:0042987]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; glycoprotein transport [GO:0034436]; high-density lipoprotein particle remodeling [GO:0034375]; intracellular cholesterol transport [GO:0032367]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; phospholipid efflux [GO:0033700]; phospholipid homeostasis [GO:0055091]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of protein secretion [GO:0050714]; regulation of cholesterol metabolic process [GO:0090181]; response to lipid [GO:0033993]; response to organic substance [GO:0010033]; reverse cholesterol transport [GO:0043691]; transmembrane transport [GO:0055085] endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037] ABC-type sterol transporter activity [GO:0034041]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; cholesterol binding [GO:0015485]; cholesterol transfer activity [GO:0120020]; floppase activity [GO:0140328]; phosphatidylcholine floppase activity [GO:0090554]; phospholipid binding [GO:0005543]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; toxin transmembrane transporter activity [GO:0019534] 0.884 -0.12598 DLSYSVPEGPWWRKK 0 8.52728 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P45877 PPIC_HUMAN Peptidyl-prolyl cis-trans isomerase C (PPIase C) (EC 5.2.1.8) (Cyclophilin C) (Rotamase C) PPIC CYPC Homo sapiens (Human) protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231] cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755] 0.91166 -0.75127 IDVKTPFVVEIADW 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.94737 0 0 0 0 0 P45880 VDAC2_HUMAN Voltage-dependent anion-selective channel protein 2 (VDAC-2) (hVDAC2) (Outer mitochondrial membrane protein porin 2) VDAC2 Homo sapiens (Human) binding of sperm to zona pellucida [GO:0007339]; mitochondrial outer membrane permeabilization [GO:0097345]; monoatomic anion transport [GO:0006820]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of protein polymerization [GO:0032272] acrosomal vesicle [GO:0001669]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; mitochondrial nucleoid [GO:0042645]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; pore complex [GO:0046930]; sperm midpiece [GO:0097225] ceramide binding [GO:0097001]; cholesterol binding [GO:0015485]; nucleotide binding [GO:0000166]; phosphatidylcholine binding [GO:0031210]; porin activity [GO:0015288]; voltage-gated monoatomic anion channel activity [GO:0008308] 0 10.869 LTFDTTFSPNTGK 9.17065 0 9.2241 0 0 0 10.0293 9.53177 10.5706 10.7211 10.5998 9.89118 10.4472 9.79385 10.8438 10.694 10.4018 10.2746 12.0126 9.9074 12.5721 12.2309 11.3306 8.82442 12.7734 13.0058 12.4215 P45954 ACDSB_HUMAN "Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial (SBCAD) (EC 1.3.8.5) (2-methyl branched chain acyl-CoA dehydrogenase) (2-MEBCAD) (2-methylbutyryl-coenzyme A dehydrogenase) (2-methylbutyryl-CoA dehydrogenase)" ACADSB Homo sapiens (Human) fatty acid metabolic process [GO:0006631]; isoleucine catabolic process [GO:0006550] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] 2-methylacyl-CoA dehydrogenase activity [GO:0003853]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; isobutyryl-CoA:FAD oxidoreductase activity [GO:0102035]; short-branched-chain-acyl-CoA dehydrogenase activity [GO:0016937] 0.87778 0.0031245 VGSFCLSEAGAGSDSFALK 0 0 0 0 0 9.80323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P45973 CBX5_HUMAN Chromobox protein homolog 5 (Antigen p25) (Heterochromatin protein 1 homolog alpha) (HP1 alpha) CBX5 HP1A Homo sapiens (Human) chromatin organization [GO:0006325]; DNA damage response [GO:0006974]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122] "chromocenter [GO:0010369]; chromosome, telomeric region [GO:0000781]; heterochromatin [GO:0000792]; histone deacetylase complex [GO:0000118]; histone methyltransferase complex [GO:0035097]; kinetochore [GO:0000776]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; site of DNA damage [GO:0090734]; transcription repressor complex [GO:0017053]" chromatin binding [GO:0003682]; DNA-binding transcription factor binding [GO:0140297]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; methylated histone binding [GO:0035064]; protein-containing complex binding [GO:0044877]; protein-macromolecule adaptor activity [GO:0030674]; ribonucleoprotein complex binding [GO:0043021] 0.78026 0.26251 GQVEYLLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3614 P45974 UBP5_HUMAN Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.4.19.12) (Deubiquitinating enzyme 5) (Isopeptidase T) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) USP5 ISOT Homo sapiens (Human) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] cytosol [GO:0005829]; lysosome [GO:0005764]; nucleus [GO:0005634] cysteine-type deubiquitinase activity [GO:0004843]; cysteine-type endopeptidase activity [GO:0004197]; ubiquitin binding [GO:0043130]; zinc ion binding [GO:0008270] 0 2.7725 DGLGGLPDIVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.39264 0 9.84801 0 0 0 10.9238 0 9.26134 0 10.5278 10.7405 P45983 MK08_HUMAN Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1) MAPK8 JNK1 PRKM8 SAPK1 SAPK1C Homo sapiens (Human) cellular response to amino acid starvation [GO:0034198]; cellular response to cadmium ion [GO:0071276]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; cellular senescence [GO:0090398]; Fc-epsilon receptor signaling pathway [GO:0038095]; JNK cascade [GO:0007254]; JUN phosphorylation [GO:0007258]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein binding [GO:0032091]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell killing [GO:0031343]; positive regulation of cyclase activity [GO:0031281]; positive regulation of deacetylase activity [GO:0090045]; positive regulation of gene expression [GO:0010628]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein metabolic process [GO:0051247]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of DNA replication origin binding [GO:1902595]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of macroautophagy [GO:0016241]; regulation of protein localization [GO:0032880]; response to mechanical stimulus [GO:0009612]; response to oxidative stress [GO:0006979]; response to UV [GO:0009411]; rhythmic process [GO:0048511]; stress-activated MAPK cascade [GO:0051403] axon [GO:0030424]; basal dendrite [GO:0097441]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; synapse [GO:0045202] ATP binding [GO:0005524]; enzyme activator activity [GO:0008047]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; JUN kinase activity [GO:0004705]; protein phosphatase binding [GO:0019903]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine kinase binding [GO:0120283] 0.88612 -0.3631 EVMDLEERTK 12.581 12.3799 0 10.2398 10.5858 0 0 0 11.2874 0 11.211 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P45984 MK09_HUMAN Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC 2.7.11.24) (JNK-55) (Stress-activated protein kinase 1a) (SAPK1a) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2) MAPK9 JNK2 PRKM9 SAPK1A Homo sapiens (Human) apoptotic signaling pathway [GO:0097190]; cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; cellular senescence [GO:0090398]; Fc-epsilon receptor signaling pathway [GO:0038095]; inflammatory response to wounding [GO:0090594]; JNK cascade [GO:0007254]; modulation of chemical synaptic transmission [GO:0050804]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription factor catabolic process [GO:1901485]; protein localization to tricellular tight junction [GO:0061833]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-binding transcription factor activity [GO:0051090]; rhythmic process [GO:0048511] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685] ATP binding [GO:0005524]; JUN kinase activity [GO:0004705]; protein serine kinase activity [GO:0106310]; protein serine/threonine/tyrosine kinase activity [GO:0004712] 0.87039 0.034023 VIEQLGTPSAEFMK 0 0 0 0 0 9.9454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P46013 KI67_HUMAN Proliferation marker protein Ki-67 (Antigen identified by monoclonal antibody Ki-67) (Antigen KI-67) (Antigen Ki67) MKI67 Homo sapiens (Human) cell cycle [GO:0007049]; cell population proliferation [GO:0008283]; regulation of chromatin organization [GO:1902275]; regulation of chromosome segregation [GO:0051983]; regulation of mitotic nuclear division [GO:0007088] chromosome [GO:0005694]; membrane [GO:0016020]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; DNA binding [GO:0003677]; RNA binding [GO:0003723] 0.96951 -5.5212 EIERPFETYK 10.3116 0 10.0497 0 0 0 10.5673 0 10.1878 10.1438 10.9052 10.6289 11.4606 8.80993 0 0 10.9452 0 9.04275 9.77375 10.1833 11.0335 0 0 10.3037 0 10.8843 P46020 KPB1_HUMAN "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (Phosphorylase kinase alpha M subunit)" PHKA1 PHKA Homo sapiens (Human) generation of precursor metabolites and energy [GO:0006091]; glycogen metabolic process [GO:0005977] cytosol [GO:0005829]; phosphorylase kinase complex [GO:0005964]; plasma membrane [GO:0005886] calmodulin binding [GO:0005516]; phosphorylase kinase activity [GO:0004689] 0.94799 -1.367 DSRQGQWQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.1648 0 0 0 0 0 0 0 9.28499 0 P46059 S15A1_HUMAN "Solute carrier family 15 member 1 (Intestinal H(+)/peptide cotransporter) (Oligopeptide transporter, small intestine isoform) (Peptide transporter 1)" SLC15A1 PEPT1 Homo sapiens (Human) dipeptide import across plasma membrane [GO:0140206]; monoatomic ion transport [GO:0006811]; protein transport [GO:0015031]; tripeptide import across plasma membrane [GO:0140207] apical plasma membrane [GO:0016324]; brush border [GO:0005903]; membrane [GO:0016020]; plasma membrane [GO:0005886] dipeptide transmembrane transporter activity [GO:0071916]; peptide:proton symporter activity [GO:0015333]; proton-dependent oligopeptide secondary active transmembrane transporter activity [GO:0005427]; tripeptide transmembrane transporter activity [GO:0042937] 0.90786 -0.73492 REHWLDWAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1651 0 0 0 0 0 0 0 P46060 RAGP1_HUMAN Ran GTPase-activating protein 1 (RanGAP1) RANGAP1 KIAA1835 SD Homo sapiens (Human) activation of GTPase activity [GO:0090630]; cellular response to vasopressin [GO:1904117]; negative regulation of protein export from nucleus [GO:0046826]; nuclear export [GO:0051168]; nucleocytoplasmic transport [GO:0006913]; protein sumoylation [GO:0016925]; response to axon injury [GO:0048678]; signal transduction [GO:0007165] aggresome [GO:0016235]; axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; cytoplasmic periphery of the nuclear pore complex [GO:1990723]; cytosol [GO:0005829]; dendrite [GO:0030425]; intracellular membrane-bounded organelle [GO:0043231]; kinetochore [GO:0000776]; mitotic spindle [GO:0072686]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear pore cytoplasmic filaments [GO:0044614]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; SUMO ligase complex [GO:0106068] cadherin binding [GO:0045296]; GTPase activator activity [GO:0005096]; RNA binding [GO:0003723]; small GTPase binding [GO:0031267]; ubiquitin protein ligase binding [GO:0031625] 0.76757 0.27773 GAVAIADAIRGGLPK 0 0 0 0 0 0 0 0 0 0 0 8.93687 9.36232 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P46063 RECQ1_HUMAN "ATP-dependent DNA helicase Q1 (EC 3.6.4.12) (DNA helicase, RecQ-like type 1) (RecQ1) (DNA-dependent ATPase Q1) (RecQ protein-like 1)" RECQL RECQ1 RECQL1 Homo sapiens (Human) DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724] chromosome [GO:0005694]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA helicase activity [GO:0003678]; DNA/DNA annealing activity [GO:1990814]; four-way junction helicase activity [GO:0009378] 0.87922 0.011644 EDFPWSGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.07564 0 0 P46087 NOP2_HUMAN Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase (EC 2.1.1.-) (Nucleolar protein 1) (Nucleolar protein 2 homolog) (Proliferating-cell nucleolar antigen p120) (Proliferation-associated nucleolar protein p120) NOP2 NOL1 NSUN1 Homo sapiens (Human) maturation of LSU-rRNA [GO:0000470]; positive regulation of cell population proliferation [GO:0008284]; regulation of signal transduction by p53 class mediator [GO:1901796]; ribosomal large subunit assembly [GO:0000027]; rRNA base methylation [GO:0070475] nucleolus [GO:0005730]; nucleoplasm [GO:0005654] RNA binding [GO:0003723]; rRNA (cytosine-C5-)-methyltransferase activity [GO:0009383] 0.91363 -0.82112 EVTPESGPPK 0 0 0 0 9.12866 11.7694 0 0 0 0 0 0 0 0 0 10.7751 0 9.07178 0 0 0 0 0 0 0 10.061 0 P46093 GPR4_HUMAN G-protein coupled receptor 4 (G-protein coupled receptor 6C.l) (GPR6C.l) GPR4 Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; angiogenesis involved in wound healing [GO:0060055]; G protein-coupled receptor signaling pathway [GO:0007186]; glomerular mesangial cell development [GO:0072144]; negative regulation of angiogenesis [GO:0016525]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inflammatory response [GO:0050729]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of cell adhesion [GO:0030155]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930] 0.7456 0.3179 GNHTWEGCHVDSR 0 0 0 0 11.8151 0 13.7303 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.84331 0 0 0 0 P46100 ATRX_HUMAN Transcriptional regulator ATRX (EC 3.6.4.12) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf-HX) ATRX RAD54L XH2 Homo sapiens (Human) "cellular response to hydroxyurea [GO:0072711]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; chromosome organization involved in meiotic cell cycle [GO:0070192]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA methylation [GO:0006306]; DNA repair [GO:0006281]; forebrain development [GO:0030900]; meiotic spindle organization [GO:0000212]; multicellular organism growth [GO:0035264]; negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric [GO:1904908]; nucleosome assembly [GO:0006334]; positive regulation of nuclear cell cycle DNA replication [GO:0010571]; positive regulation of telomere maintenance [GO:0032206]; positive regulation of telomeric RNA transcription from RNA pol II promoter [GO:1901582]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic forelimb morphogenesis [GO:0035128]; protein localization to chromosome, telomeric region [GO:0070198]; regulation of DNA-templated transcription [GO:0006355]; replication fork processing [GO:0031297]; seminiferous tubule development [GO:0072520]; Sertoli cell development [GO:0060009]; spermatogenesis [GO:0007283]; subtelomeric heterochromatin formation [GO:0031509]; transcription by RNA polymerase II [GO:0006366]" "chromosome, subtelomeric region [GO:0099115]; chromosome, telomeric region [GO:0000781]; condensed chromosome, centromeric region [GO:0000779]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; PML body [GO:0016605]" ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent chromatin remodeler activity [GO:0140658]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; chromo shadow domain binding [GO:0070087]; DNA translocase activity [GO:0015616]; helicase activity [GO:0004386]; histone binding [GO:0042393]; metal ion binding [GO:0046872]; methylated histone binding [GO:0035064] 0.95207 -1.4475 KAHLALEEDLNSEFR 0 0 0 0 0 0 0 0 9.15692 9.60251 0 0 0 0 0 0 0 10.049 0 9.35019 0 0 0 0 9.67909 0 0 P46109 CRKL_HUMAN Crk-like protein CRKL Homo sapiens (Human) acetylcholine receptor signaling pathway [GO:0095500]; activation of GTPase activity [GO:0090630]; anterior/posterior pattern specification [GO:0009952]; B cell apoptotic process [GO:0001783]; blood vessel development [GO:0001568]; cell chemotaxis [GO:0060326]; cellular response to interleukin-7 [GO:0098761]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to xenobiotic stimulus [GO:0071466]; cerebellar neuron development [GO:0098749]; cerebral cortex development [GO:0021987]; cranial skeletal system development [GO:1904888]; dendrite development [GO:0016358]; endothelin receptor signaling pathway [GO:0086100]; establishment of cell polarity [GO:0030010]; fibroblast growth factor receptor signaling pathway [GO:0008543]; helper T cell diapedesis [GO:0035685]; hippocampus development [GO:0021766]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; lipid metabolic process [GO:0006629]; male gonad development [GO:0008584]; negative regulation of gene expression [GO:0010629]; negative regulation of protein phosphorylation [GO:0001933]; neuron migration [GO:0001764]; outflow tract morphogenesis [GO:0003151]; parathyroid gland development [GO:0060017]; pharynx development [GO:0060465]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glial cell migration [GO:1903977]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynaptic specialization assembly [GO:0098698]; Ras protein signal transduction [GO:0007265]; reelin-mediated signaling pathway [GO:0038026]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell growth [GO:0001558]; regulation of dendrite development [GO:0050773]; regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904393]; regulation of T cell migration [GO:2000404]; retinoic acid receptor signaling pathway [GO:0048384]; single fertilization [GO:0007338]; spermatogenesis [GO:0007283]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; urogenital system development [GO:0001655] cytosol [GO:0005829]; extrinsic component of postsynaptic membrane [GO:0098890]; neuromuscular junction [GO:0031594]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991] cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; phosphotyrosine residue binding [GO:0001784]; RNA binding [GO:0003723]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629] 0.37485 0.72628 SAWYMGPVSRQEAQTR 0 0 0 0 9.96365 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P46199 IF2M_HUMAN "Translation initiation factor IF-2, mitochondrial (IF-2(Mt)) (IF-2Mt) (IF2(mt))" MTIF2 Homo sapiens (Human) mitochondrial translational initiation [GO:0070124]; regulation of translational initiation [GO:0006446]; ribosome disassembly [GO:0032790] cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] "GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; translation factor activity, RNA binding [GO:0008135]; translation initiation factor activity [GO:0003743]" 0.95851 -1.8666 EAHQKAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.49374 P46379 BAG6_HUMAN Large proline-rich protein BAG6 (BAG family molecular chaperone regulator 6) (BCL2-associated athanogene 6) (BAG-6) (HLA-B-associated transcript 3) (Protein G3) (Protein Scythe) BAG6 BAT3 G3 Homo sapiens (Human) apoptotic process [GO:0006915]; brain development [GO:0007420]; cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; ER-associated misfolded protein catabolic process [GO:0071712]; immune response-activating cell surface receptor signaling pathway [GO:0002429]; internal peptidyl-lysine acetylation [GO:0018393]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; lung development [GO:0030324]; maintenance of unfolded protein involved in ERAD pathway [GO:1904378]; natural killer cell activation [GO:0030101]; negative regulation of apoptotic process [GO:0043066]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of proteolysis [GO:0045861]; positive regulation of ERAD pathway [GO:1904294]; post-translational protein targeting to endoplasmic reticulum membrane [GO:0006620]; proteasomal protein catabolic process [GO:0010498]; protein localization to cytosolic proteasome complex involved in ERAD pathway [GO:1904379]; protein stabilization [GO:0050821]; regulation of embryonic development [GO:0045995]; regulation of protein stability [GO:0031647]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130]; tail-anchored membrane protein insertion into ER membrane [GO:0071816]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511] BAT3 complex [GO:0071818]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] Hsp70 protein binding [GO:0030544]; identical protein binding [GO:0042802]; misfolded protein binding [GO:0051787]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; ribosome binding [GO:0043022]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381] 0.11029 1.1246 AGSSESIAAFIQR 0 0 0 0 0 0 0 0 0 0 10.1454 9.04693 0 0 0 0 9.04729 0 9.45841 0 8.86993 0 0 0 0 0 0 P46459 NSF_HUMAN Vesicle-fusing ATPase (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein) (NEM-sensitive fusion protein) (Vesicular-fusion protein NSF) NSF Homo sapiens (Human) exocytosis [GO:0006887]; Golgi to plasma membrane protein transport [GO:0043001]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; plasma membrane fusion [GO:0045026]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of receptor recycling [GO:0001921]; potassium ion transport [GO:0006813]; regulation of exocytosis [GO:0017157]; SNARE complex disassembly [GO:0035494]; vesicle-mediated transport [GO:0016192] cytosol [GO:0005829]; dendritic shaft [GO:0043198]; Golgi apparatus [GO:0005794]; Golgi stack [GO:0005795]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein disaggregase activity [GO:0140545]; ionotropic glutamate receptor binding [GO:0035255]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; SNARE binding [GO:0000149]; syntaxin-1 binding [GO:0017075] 0.16337 0.9866 GEPATGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.95965 0 0 0 0 P46531 NOTC1_HUMAN Neurogenic locus notch homolog protein 1 (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] NOTCH1 TAN1 Homo sapiens (Human) animal organ regeneration [GO:0031100]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in embryonic digit morphogenesis [GO:1902263]; arterial endothelial cell differentiation [GO:0060842]; astrocyte differentiation [GO:0048708]; atrioventricular node development [GO:0003162]; atrioventricular valve morphogenesis [GO:0003181]; auditory receptor cell fate commitment [GO:0009912]; axon guidance [GO:0007411]; branching morphogenesis of an epithelial tube [GO:0048754]; calcium-ion regulated exocytosis [GO:0017156]; cardiac atrium morphogenesis [GO:0003209]; cardiac chamber formation [GO:0003207]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac left ventricle morphogenesis [GO:0003214]; cardiac muscle cell myoblast differentiation [GO:0060379]; cardiac muscle cell proliferation [GO:0060038]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right atrium morphogenesis [GO:0003213]; cardiac right ventricle formation [GO:0003219]; cardiac septum morphogenesis [GO:0060411]; cardiac vascular smooth muscle cell development [GO:0060948]; cardiac ventricle morphogenesis [GO:0003208]; cell differentiation in spinal cord [GO:0021515]; cell migration involved in endocardial cushion formation [GO:0003273]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to hypoxia [GO:0071456]; cellular response to tumor cell [GO:0071228]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cilium assembly [GO:0060271]; collecting duct development [GO:0072044]; compartment pattern specification [GO:0007386]; coronary artery morphogenesis [GO:0060982]; coronary sinus valve morphogenesis [GO:0003182]; coronary vein morphogenesis [GO:0003169]; determination of left/right symmetry [GO:0007368]; distal tubule development [GO:0072017]; embryonic hindlimb morphogenesis [GO:0035116]; endocardial cell differentiation [GO:0060956]; endocardial cushion morphogenesis [GO:0003203]; endocardium development [GO:0003157]; endocardium morphogenesis [GO:0003160]; endoderm development [GO:0007492]; epidermal cell fate specification [GO:0009957]; epithelial cell fate commitment [GO:0072148]; epithelial cell proliferation [GO:0050673]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; forebrain development [GO:0030900]; foregut morphogenesis [GO:0007440]; glomerular mesangial cell development [GO:0072144]; growth involved in heart morphogenesis [GO:0003241]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula morphogenesis [GO:0061384]; homeostasis of number of cells within a tissue [GO:0048873]; humoral immune response [GO:0006959]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; inhibition of neuroepithelial cell differentiation [GO:0002085]; interleukin-17-mediated signaling pathway [GO:0097400]; keratinocyte differentiation [GO:0030216]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; lung development [GO:0030324]; luteolysis [GO:0001554]; mesenchymal cell development [GO:0014031]; mitral valve formation [GO:0003192]; negative regulation of anoikis [GO:2000811]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of catalytic activity [GO:0043086]; negative regulation of cell adhesion molecule production [GO:0060354]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell proliferation involved in heart valve morphogenesis [GO:0003252]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of extracellular matrix constituent secretion [GO:0003332]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of neurogenesis [GO:0050768]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of photoreceptor cell differentiation [GO:0046533]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube development [GO:0021915]; neuroendocrine cell differentiation [GO:0061101]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation [GO:0003270]; oligodendrocyte differentiation [GO:0048709]; outflow tract morphogenesis [GO:0003151]; pericardium morphogenesis [GO:0003344]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of apoptotic process involved in morphogenesis [GO:1902339]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac epithelial to mesenchymal transition [GO:0062043]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of viral genome replication [GO:0045070]; prostate gland epithelium morphogenesis [GO:0060740]; protein catabolic process [GO:0030163]; protein import into nucleus [GO:0006606]; pulmonary valve morphogenesis [GO:0003184]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of extracellular matrix assembly [GO:1901201]; regulation of somitogenesis [GO:0014807]; regulation of stem cell proliferation [GO:0072091]; regulation of transcription by RNA polymerase II [GO:0006357]; response to corticosteroid [GO:0031960]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; retinal cone cell differentiation [GO:0042670]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell division [GO:0048103]; spermatogenesis [GO:0007283]; sprouting angiogenesis [GO:0002040]; T-helper 17 type immune response [GO:0072538]; tissue regeneration [GO:0042246]; transcription by RNA polymerase II [GO:0006366]; tube formation [GO:0035148]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; venous endothelial cell differentiation [GO:0060843]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222] acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; MAML1-RBP-Jkappa- ICN1 complex [GO:0002193]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] calcium ion binding [GO:0005509]; chromatin DNA binding [GO:0031490]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; identical protein binding [GO:0042802]; Notch binding [GO:0005112]; transcription coactivator activity [GO:0003713]; transcription regulator activator activity [GO:0140537]; transmembrane signaling receptor activity [GO:0004888] 0.88324 -0.27509 DIAQERMHHDIVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.20523 0 0 0 0 0 0 0 9.91569 9.59412 0 P46597 ASMT_HUMAN Acetylserotonin O-methyltransferase (EC 2.1.1.4) (Hydroxyindole O-methyltransferase) (HIOMT) ASMT Homo sapiens (Human) indolalkylamine biosynthetic process [GO:0046219]; lipid metabolic process [GO:0006629]; melatonin biosynthetic process [GO:0030187]; methylation [GO:0032259]; translation [GO:0006412] cytosol [GO:0005829] acetylserotonin O-methyltransferase activity [GO:0017096]; identical protein binding [GO:0042802]; O-methyltransferase activity [GO:0008171]; protein homodimerization activity [GO:0042803]; S-methyltransferase activity [GO:0008172] 0.80606 0.23533 VLHDWADGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.32341 0 0 0 0 0 0 0 0 0 0 0 P46663 BKRB1_HUMAN B1 bradykinin receptor (B1R) (BK-1 receptor) BDKRB1 BRADYB1 Homo sapiens (Human) cell migration [GO:0016477]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell growth [GO:0030308]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; sensory perception of pain [GO:0019233] endoplasmic reticulum [GO:0005783]; neuron projection [GO:0043005]; plasma membrane [GO:0005886] bradykinin receptor activity [GO:0004947]; peptide binding [GO:0042277] 0.54132 0.5792 EIFQLFWRN 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.02031 0 0 0 0 0 0 9.13743 0 0 P46734 MP2K3_HUMAN Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase 3) (MAPKK 3) (EC 2.7.12.2) (MAPK/ERK kinase 3) (MEK 3) (Stress-activated protein kinase kinase 2) (SAPK kinase 2) (SAPKK-2) (SAPKK2) MAP2K3 MEK3 MKK3 PRKMK3 SKK2 Homo sapiens (Human) cardiac muscle contraction [GO:0060048]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to sorbitol [GO:0072709]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular senescence [GO:0090398]; heart development [GO:0007507]; inflammatory response [GO:0006954]; MAPK cascade [GO:0000165]; negative regulation of hippo signaling [GO:0035331]; p38MAPK cascade [GO:0038066]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of protein kinase activity [GO:0045860]; protein phosphorylation [GO:0006468]; regulation of cytokine production [GO:0001817]; response to ischemia [GO:0002931]; signal transduction [GO:0007165]; stress-activated protein kinase signaling cascade [GO:0031098] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654] ATP binding [GO:0005524]; MAP kinase kinase activity [GO:0004708]; protein kinase binding [GO:0019901]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713] 0.60482 0.43839 INPELNQK 0 0 0 0 0 0 0 0 0 10.4049 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P46736 BRCC3_HUMAN Lys-63-specific deubiquitinase BRCC36 (EC 3.4.19.-) (BRCA1-A complex subunit BRCC36) (BRCA1/BRCA2-containing complex subunit 3) (BRCA1/BRCA2-containing complex subunit 36) (BRISC complex subunit BRCC36) BRCC3 BRCC36 C6.1A CXorf53 Homo sapiens (Human) cell division [GO:0051301]; cellular response to ionizing radiation [GO:0071479]; DNA repair-dependent chromatin remodeling [GO:0140861]; double-strand break repair [GO:0006302]; histone H2A K63-linked deubiquitination [GO:0070537]; histone H2A monoubiquitination [GO:0035518]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; mitotic G2/M transition checkpoint [GO:0044818]; positive regulation of DNA repair [GO:0045739]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227]; protein autoubiquitination [GO:0051865]; protein deubiquitination [GO:0016579]; protein K63-linked deubiquitination [GO:0070536]; regulation of DNA damage checkpoint [GO:2000001]; regulation of DNA repair [GO:0006282]; response to ionizing radiation [GO:0010212]; response to X-ray [GO:0010165] BRCA1-A complex [GO:0070531]; BRISC complex [GO:0070552]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear ubiquitin ligase complex [GO:0000152]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]; ubiquitin ligase complex [GO:0000151] cysteine-type deubiquitinase activity [GO:0004843]; enzyme regulator activity [GO:0030234]; K63-linked deubiquitinase activity [GO:0061578]; metal ion binding [GO:0046872]; metal-dependent deubiquitinase activity [GO:0140492]; metallopeptidase activity [GO:0008237]; polyubiquitin modification-dependent protein binding [GO:0031593] 0.7562 0.30747 LAELTGRPMR 9.93319 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P46776 RL27A_HUMAN Large ribosomal subunit protein uL15 (60S ribosomal protein L27a) RPL27A Homo sapiens (Human) cytoplasmic translation [GO:0002181]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; endoplasmic reticulum [GO:0005783]; membrane [GO:0016020]; synapse [GO:0045202] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0 3.3043 TGAAPIIDVVR 0 0 0 0 0 0 9.36126 9.42823 9.64967 0 0 0 9.42807 0 9.66133 0 0 0 9.41136 9.38059 0 8.84818 0 8.85748 11.0874 10.5789 11.056 P46777 RL5_HUMAN Large ribosomal subunit protein uL18 (60S ribosomal protein L5) RPL5 MSTP030 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; negative regulation of protein neddylation [GO:2000435]; negative regulation of ubiquitin protein ligase activity [GO:1904667]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; positive regulation of gene expression [GO:0010628]; positive regulation of translation [GO:0045727]; protein stabilization [GO:0050821]; regulation of signal transduction by p53 class mediator [GO:1901796]; ribosomal large subunit assembly [GO:0000027]; ribosomal large subunit biogenesis [GO:0042273]; rRNA processing [GO:0006364]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904] 5S rRNA binding [GO:0008097]; mRNA 3'-UTR binding [GO:0003730]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin ligase inhibitor activity [GO:1990948]; ubiquitin protein ligase binding [GO:0031625] 0.31854 0.78959 IEGDMIVCAAYAHELPK 0 0 0 10.0933 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2403 0 0 P46778 RL21_HUMAN Large ribosomal subunit protein eL21 (60S ribosomal protein L21) RPL21 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; endoplasmic reticulum [GO:0005783]; membrane [GO:0016020] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.23729 0.85099 GMGTVQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.27125 12.1203 12.3997 12.4088 0 0 0 0 0 0 0 0 0 P46779 RL28_HUMAN Large ribosomal subunit protein eL28 (60S ribosomal protein L28) RPL28 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; translation [GO:0006412] cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; synapse [GO:0045202] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.0061728 2.6812 QTYSTEPNNLK 0 0 0 0 0 0 11.2932 8.13766 0 0 12.1052 0 0 0 0 0 12.0208 0 0 0 0 0 0 0 0 10.0067 0 P46781 RS9_HUMAN Small ribosomal subunit protein uS4 (40S ribosomal protein S9) RPS9 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; positive regulation of cell population proliferation [GO:0008284]; ribosomal small subunit biogenesis [GO:0042274]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; ribosome [GO:0005840]; small-subunit processome [GO:0032040]; synapse [GO:0045202] RNA binding [GO:0003723]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation regulator activity [GO:0045182] 0.35564 0.75844 IEDFLER 0 0 0 0 0 0 0 8.37456 0 0 0 11.5693 9.12177 8.72874 9.04851 9.32441 9.71017 12.1648 10.0479 0 8.8794 8.7733 8.84075 8.72952 9.54913 11.6641 9.24907 P46782 RS5_HUMAN "Small ribosomal subunit protein uS7 (40S ribosomal protein S5) [Cleaved into: Small ribosomal subunit protein uS7, N-terminally processed (40S ribosomal protein S5, N-terminally processed)]" RPS5 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; regulation of translational fidelity [GO:0006450]; ribosomal small subunit assembly [GO:0000028]; ribosomal small subunit biogenesis [GO:0042274]; translation [GO:0006412]; translational initiation [GO:0006413] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; ribonucleoprotein complex [GO:1990904]; ribosome [GO:0005840]; small-subunit processome [GO:0032040] mRNA binding [GO:0003729]; RNA binding [GO:0003723]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735] 0.68638 0.38789 GSSNSYAIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.8906 9.05327 0 P46821 MAP1B_HUMAN Microtubule-associated protein 1B (MAP-1B) [Cleaved into: MAP1B heavy chain; MAP1 light chain LC1] MAP1B Homo sapiens (Human) axon extension [GO:0048675]; axonogenesis [GO:0007409]; cellular response to growth factor stimulus [GO:0071363]; cellular response to peptide hormone stimulus [GO:0071375]; dendrite development [GO:0016358]; developmental maturation [GO:0021700]; establishment of monopolar cell polarity [GO:0061162]; induction of synaptic plasticity by chemical substance [GO:0051915]; microtubule bundle formation [GO:0001578]; microtubule cytoskeleton organization [GO:0000226]; mitochondrion transport along microtubule [GO:0047497]; negative regulation of intracellular transport [GO:0032387]; negative regulation of microtubule depolymerization [GO:0007026]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; odontoblast differentiation [GO:0071895]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of axon extension [GO:0045773]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neuron differentiation [GO:0045666]; regulation of microtubule depolymerization [GO:0031114]; response to carbohydrate [GO:0009743]; response to estradiol [GO:0032355]; response to inorganic substance [GO:0010035]; response to insecticide [GO:0017085]; response to mechanical stimulus [GO:0009612]; response to vitamin A [GO:0033189]; response to xenobiotic stimulus [GO:0009410]; synapse assembly [GO:0007416] apical dendrite [GO:0097440]; axon [GO:0030424]; basal dendrite [GO:0097441]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; growth cone [GO:0030426]; hippocampal mossy fiber [GO:0097457]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; somatodendritic compartment [GO:0036477]; synapse [GO:0045202]; varicosity [GO:0043196] actin binding [GO:0003779]; microtubule binding [GO:0008017]; phospholipid binding [GO:0005543]; protein-containing complex binding [GO:0044877]; structural molecule activity [GO:0005198] 0.92365 -1.1668 DLSTPGLEK 11.0912 0 0 0 0 0 0 0 0 0 9.35905 10.0732 0 0 0 9.63733 0 0 0 0 0 0 0 0 0 0 0 P46934 NEDD4_HUMAN E3 ubiquitin-protein ligase NEDD4 (EC 2.3.2.26) (Cell proliferation-inducing gene 53 protein) (HECT-type E3 ubiquitin transferase NEDD4) (Neural precursor cell expressed developmentally down-regulated protein 4) (NEDD-4) NEDD4 KIAA0093 NEDD4-1 RPF1 PIG53 Homo sapiens (Human) cellular response to UV [GO:0034644]; formation of structure involved in a symbiotic process [GO:0044111]; glucocorticoid receptor signaling pathway [GO:0042921]; innate immune response [GO:0045087]; lysosomal transport [GO:0007041]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; negative regulation of sodium ion transport [GO:0010766]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; neuromuscular junction development [GO:0007528]; neuron projection development [GO:0031175]; positive regulation of nucleocytoplasmic transport [GO:0046824]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein catabolic process [GO:0045732]; progesterone receptor signaling pathway [GO:0050847]; protein K63-linked ubiquitination [GO:0070534]; protein targeting to lysosome [GO:0006622]; protein ubiquitination [GO:0016567]; receptor catabolic process [GO:0032801]; receptor internalization [GO:0031623]; regulation of dendrite morphogenesis [GO:0048814]; regulation of macroautophagy [GO:0016241]; regulation of membrane potential [GO:0042391]; regulation of monoatomic ion transmembrane transport [GO:0034765]; regulation of potassium ion transmembrane transporter activity [GO:1901016]; regulation of synapse organization [GO:0050807]; response to calcium ion [GO:0051592]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding [GO:0046755] apicolateral plasma membrane [GO:0016327]; cell cortex [GO:0005938]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151] beta-2 adrenergic receptor binding [GO:0031698]; enzyme binding [GO:0019899]; molecular function activator activity [GO:0140677]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; proline-rich region binding [GO:0070064]; protein domain specific binding [GO:0019904]; RNA polymerase binding [GO:0070063]; sodium channel inhibitor activity [GO:0019871]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630] 0.86295 0.088068 ATVLEDSYRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.25505 0 8.80983 0 0 0 9.54197 0 0 0 P46939 UTRN_HUMAN Utrophin (Dystrophin-related protein 1) (DRP-1) UTRN DMDL DRP1 Homo sapiens (Human) muscle contraction [GO:0006936]; muscle organ development [GO:0007517]; positive regulation of cell-matrix adhesion [GO:0001954]; regulation of sodium ion transmembrane transporter activity [GO:2000649]; synaptic signaling [GO:0099536] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dystrophin-associated glycoprotein complex [GO:0016010]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383] actin binding [GO:0003779]; integrin binding [GO:0005178]; protein kinase binding [GO:0019901]; vinculin binding [GO:0017166]; zinc ion binding [GO:0008270] 0.96923 -6.0596 AFEADSTVIEK 10.4289 0 0 0 0 0 0 0 0 10.4535 0 10.4928 9.06725 0 9.87983 0 0 0 0 0 0 0 11.0286 0 10.2248 10.2206 0 P46940 IQGA1_HUMAN Ras GTPase-activating-like protein IQGAP1 (p195) IQGAP1 KIAA0051 Homo sapiens (Human) cell migration [GO:0016477]; cellular response to calcium ion [GO:0071277]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast migration [GO:0010761]; mitotic actomyosin contractile ring assembly actin filament organization [GO:1903479]; negative regulation of dephosphorylation [GO:0035305]; neuron projection extension [GO:1990138]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; podocyte development [GO:0072015]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase activity [GO:0045860]; regulation of cytokine production [GO:0001817]; regulation of GTPase activity [GO:0043087]; regulation of mitotic cell cycle [GO:0007346]; signal transduction [GO:0007165] actin filament [GO:0005884]; apical plasma membrane [GO:0016324]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell cortex [GO:0005938]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; growth cone [GO:0030426]; lateral plasma membrane [GO:0016328]; microtubule [GO:0005874]; midbody [GO:0030496]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]; ruffle [GO:0001726]; secretory granule membrane [GO:0030667]; slit diaphragm [GO:0036057] "actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; GTPase activator activity [GO:0005096]; GTPase inhibitor activity [GO:0005095]; MAP-kinase scaffold activity [GO:0005078]; molecular adaptor activity [GO:0060090]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein serine/threonine kinase activator activity [GO:0043539]; S100 protein binding [GO:0044548]; small GTPase binding [GO:0031267]" 0 13.044 ALQSPALGLR 0 8.29089 0 0 0 0 0 10.87 14.2323 9.49651 0 0 0 0 0 0 0 0 8.87249 0 9.29522 0 0 0 10.3424 0 9.99915 P46952 3HAO_HUMAN "3-hydroxyanthranilate 3,4-dioxygenase (EC 1.13.11.6) (3-hydroxyanthranilate oxygenase) (3-HAO) (h3HAO) (3-hydroxyanthranilic acid dioxygenase) (HAD)" HAAO Homo sapiens (Human) 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; NAD biosynthetic process [GO:0009435]; neuron cellular homeostasis [GO:0070050]; quinolinate biosynthetic process [GO:0019805]; quinolinate metabolic process [GO:0046874]; response to cadmium ion [GO:0046686]; response to zinc ion [GO:0010043]; tryptophan catabolic process [GO:0006569] cytoplasm [GO:0005737]; cytosol [GO:0005829] "3-hydroxyanthranilate 3,4-dioxygenase activity [GO:0000334]; electron transfer activity [GO:0009055]; ferrous iron binding [GO:0008198]" 0.77275 0.27261 LETELDGLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15.2435 0 0 P46977 STT3A_HUMAN Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (Oligosaccharyl transferase subunit STT3A) (STT3-A) (EC 2.4.99.18) (B5) (Integral membrane protein 1) (Transmembrane protein TMC) STT3A ITM1 TMC Homo sapiens (Human) co-translational protein modification [GO:0043686]; post-translational protein modification [GO:0043687]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279] endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; oligosaccharyltransferase complex [GO:0008250]; oligosaccharyltransferase III complex [GO:0035000] dolichyl-diphosphooligosaccharide-protein glycotransferase activity [GO:0004579]; metal ion binding [GO:0046872] 0.88264 -0.088867 DLDNRGLSR 0 0 0 0 0 0 0 0 8.80274 0 0 0 0 0 0 0 13.8257 0 0 8.74126 0 0 0 0 0 0 0 P47211 GALR1_HUMAN Galanin receptor type 1 (GAL1-R) (GALR-1) GALR1 GALNR GALNR1 Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; negative regulation of adenylate cyclase activity [GO:0007194]; neuropeptide signaling pathway [GO:0007218]; positive regulation of cortisol secretion [GO:0051464]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of transcription by RNA polymerase II [GO:0045944] membrane [GO:0016020]; plasma membrane [GO:0005886] G protein-coupled peptide receptor activity [GO:0008528]; galanin receptor activity [GO:0004966]; neuropeptide binding [GO:0042923]; peptide hormone binding [GO:0017046] 0.95428 -1.5294 QVFKCHIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.85462 0 0 0 0 9.44812 0 0 0 0 0 0 P47710 CASA1_HUMAN Alpha-S1-casein [Cleaved into: Casoxin-D] CSN1S1 CASA CSN1 Homo sapiens (Human) response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570] extracellular region [GO:0005576]; extracellular space [GO:0005615] 0.96603 -2.3575 LPLRYPER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.28142 0 0 0 0 0 0 0 0 0 0 0 P47712 PA24A_HUMAN Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)] PLA2G4A CPLA2 PLA2G4 Homo sapiens (Human) arachidonic acid metabolic process [GO:0019369]; arachidonic acid secretion [GO:0050482]; cellular response to antibiotic [GO:0071236]; establishment of localization in cell [GO:0051649]; glycerol metabolic process [GO:0006071]; glycerophospholipid catabolic process [GO:0046475]; icosanoid metabolic process [GO:0006690]; leukotriene biosynthetic process [GO:0019370]; monoacylglycerol biosynthetic process [GO:0006640]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylcholine catabolic process [GO:0034638]; phosphatidylglycerol catabolic process [GO:0034478]; platelet activating factor biosynthetic process [GO:0006663]; positive regulation of macrophage activation [GO:0043032]; positive regulation of platelet activation [GO:0010572]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of T-helper 1 type immune response [GO:0002827]; prostaglandin biosynthetic process [GO:0001516]; regulation of cell population proliferation [GO:0042127] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial inner membrane [GO:0005743]; nuclear envelope [GO:0005635]; nucleus [GO:0005634] calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; calcium-dependent phospholipid binding [GO:0005544]; calcium-independent phospholipase A2 activity [GO:0047499]; ceramide 1-phosphate binding [GO:1902387]; lysophospholipase activity [GO:0004622]; O-acyltransferase activity [GO:0008374]; phosphatidyl phospholipase B activity [GO:0102545]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; phospholipase A2 activity [GO:0004623] 0.41971 0.68093 ELLLAEK 8.75422 0 0 0 0 0 9.24859 9.27268 9.06437 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P47736 RPGP1_HUMAN Rap1 GTPase-activating protein 1 (Rap1GAP) (Rap1GAP1) RAP1GAP KIAA0474 RAP1GA1 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; adaptive immune response [GO:0002250]; cellular response to glial cell derived neurotrophic factor [GO:1990792]; negative regulation of GTP binding [GO:1904425]; negative regulation of microvillus assembly [GO:1903697]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of thyroid gland epithelial cell proliferation [GO:1904442]; positive regulation of GTPase activity [GO:0043547]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; early endosome [GO:0005769]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; neuronal cell body [GO:0043025] GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; protein homodimerization activity [GO:0042803]; small GTPase binding [GO:0031267] 0.96372 -2.6521 FAKLEER 9.6213 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2689 10.3708 0 0 0 8.75041 10.2836 0 10.1558 0 0 9.94376 P47756 CAPZB_HUMAN F-actin-capping protein subunit beta (CapZ beta) CAPZB Homo sapiens (Human) actin polymerization or depolymerization [GO:0008154]; barbed-end actin filament capping [GO:0051016]; cell morphogenesis [GO:0000902]; cytoskeleton organization [GO:0007010]; lamellipodium assembly [GO:0030032]; negative regulation of filopodium assembly [GO:0051490]; regulation of cell morphogenesis [GO:0022604]; regulation of lamellipodium assembly [GO:0010591] actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cortical cytoskeleton [GO:0030863]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; F-actin capping protein complex [GO:0008290]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; lamellipodium [GO:0030027]; membrane [GO:0016020]; postsynaptic density [GO:0014069]; sarcomere [GO:0030017]; Schaffer collateral - CA1 synapse [GO:0098685]; sperm connecting piece [GO:0097224]; WASH complex [GO:0071203] actin binding [GO:0003779]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296] 0 2.8656 KAGDGSK 0 0 0 0 0 0 0 8.81333 0 9.45061 0 0 0 0 0 9.36238 9.58374 9.18658 0 10.4111 0 0 0 0 11.9562 10.8734 10.3668 P47870 GBRB2_HUMAN Gamma-aminobutyric acid receptor subunit beta-2 (GABA(A) receptor subunit beta-2) GABRB2 Homo sapiens (Human) "cellular response to histamine [GO:0071420]; chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; cochlea development [GO:0090102]; gamma-aminobutyric acid signaling pathway [GO:0007214]; inhibitory synapse assembly [GO:1904862]; inner ear receptor cell development [GO:0060119]; innervation [GO:0060384]; monoatomic ion transmembrane transport [GO:0034220]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; sensory perception of sound [GO:0007605]; signal transduction [GO:0007165]; synaptic transmission, GABAergic [GO:0051932]" chloride channel complex [GO:0034707]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; GABA-A receptor complex [GO:1902711]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynaptic specialization membrane [GO:0099634]; presynaptic active zone membrane [GO:0048787]; synapse [GO:0045202] chloride channel activity [GO:0005254]; GABA-A receptor activity [GO:0004890]; GABA-gated chloride ion channel activity [GO:0022851]; inhibitory extracellular ligand-gated monoatomic ion channel activity [GO:0005237]; ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; neurotransmitter receptor activity [GO:0030594]; transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315] 0.96826 -3.6502 AAEKAASANNEKMR 0 8.91958 0 0 0 0 0 9.34441 0 9.5002 0 0 8.93758 0 0 0 9.70839 0 0 0 0 0 0 0 0 0 0 P47871 GLR_HUMAN Glucagon receptor (GL-R) GCGR Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell surface receptor signaling pathway [GO:0007166]; cellular response to glucagon stimulus [GO:0071377]; cellular response to starvation [GO:0009267]; exocytosis [GO:0006887]; generation of precursor metabolites and energy [GO:0006091]; glucose homeostasis [GO:0042593]; hormone-mediated signaling pathway [GO:0009755]; positive regulation of gene expression [GO:0010628]; regulation of blood pressure [GO:0008217]; regulation of glycogen metabolic process [GO:0070873]; response to nutrient [GO:0007584]; response to starvation [GO:0042594] endosome [GO:0005768]; membrane [GO:0016020]; plasma membrane [GO:0005886] glucagon receptor activity [GO:0004967]; GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; peptide hormone binding [GO:0017046] 0.95429 -1.5181 IVQLLVAKLRAR 0 0 0 0 0 0 0 0 0 0 0 0 0 11.178 0 0 0 0 0 0 0 0 0 0 0 0 0 P47883 OR3A4_HUMAN Putative olfactory receptor 3A4 (Olfactory receptor 17-24) (OR17-24) (Olfactory receptor 3A5) OR3A4P OR3A4 OR3A5P Homo sapiens (Human) sensory perception of smell [GO:0007608]; signal transduction [GO:0007165] membrane [GO:0016020]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.83027 0.2026 DLGNSGNDSVVTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.94181 P47895 AL1A3_HUMAN Retinaldehyde dehydrogenase 3 (RALDH-3) (RalDH3) (EC 1.2.1.36) (Aldehyde dehydrogenase 6) (Aldehyde dehydrogenase family 1 member A3) (ALDH1A3) ALDH1A3 ALDH6 Homo sapiens (Human) apoptotic process [GO:0006915]; embryonic camera-type eye development [GO:0031076]; embryonic eye morphogenesis [GO:0048048]; face development [GO:0060324]; Harderian gland development [GO:0070384]; inner ear morphogenesis [GO:0042472]; locomotory behavior [GO:0007626]; neuromuscular process controlling balance [GO:0050885]; nucleus accumbens development [GO:0021768]; olfactory pit development [GO:0060166]; optic cup morphogenesis involved in camera-type eye development [GO:0002072]; positive regulation of apoptotic process [GO:0043065]; protein homotetramerization [GO:0051289]; retinal metabolic process [GO:0042574]; retinoic acid biosynthetic process [GO:0002138]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]; righting reflex [GO:0060013] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062] aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; NAD+ binding [GO:0070403]; protein homodimerization activity [GO:0042803]; retinal dehydrogenase activity [GO:0001758]; thyroid hormone binding [GO:0070324] 0.87356 0.026053 LECGGSAMEDK 0 0 0 0 0 0 0 0 0 0 0 8.32998 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P47897 SYQ_HUMAN Glutamine--tRNA ligase (EC 6.1.1.18) (Glutaminyl-tRNA synthetase) (GlnRS) QARS1 QARS Homo sapiens (Human) brain development [GO:0007420]; glutaminyl-tRNA aminoacylation [GO:0006425]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; tRNA aminoacylation for protein translation [GO:0006418] aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; protein-containing complex [GO:0032991] ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]; protein kinase binding [GO:0019901]; protein kinase inhibitor activity [GO:0004860] 0.95464 -1.5751 FSEGEATLR 0 0 12.3645 0 0 0 8.84009 10.4598 9.83999 8.63238 0 11.8746 0 0 0 0 9.46408 0 0 0 0 0 14.4938 0 0 0 0 P47914 RL29_HUMAN Large ribosomal subunit protein eL29 (60S ribosomal protein L29) (Cell surface heparin-binding protein HIP) RPL29 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; embryo implantation [GO:0007566]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; membrane [GO:0016020] cadherin binding [GO:0045296]; heparin binding [GO:0008201]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.356 0.75717 AQAAAPASVPAQAPK 0 9.76878 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6701 0 0 0 0 0 P47944 MT4_HUMAN Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV) MT4 Homo sapiens (Human) cellular response to copper ion [GO:0071280]; intracellular monoatomic cation homeostasis [GO:0030003] metal ion binding [GO:0046872] 0.90563 -0.72855 CTTCNCKTYWK 0 0 0 0 0 0 0 0 0 0 9.88798 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P47972 NPTX2_HUMAN Neuronal pentraxin-2 (NP2) (Neuronal pentraxin II) (NP-II) NPTX2 Homo sapiens (Human) associative learning [GO:0008306]; chemical synaptic transmission [GO:0007268]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] extracellular region [GO:0005576]; glutamatergic synapse [GO:0098978] carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872] 0.56985 0.48316 CEGLAGGK 0 0 0 0 0 0 0 8.25984 0 0 11.2797 0 10.0626 0 0 10.8662 9.06218 0 9.14379 0 0 9.74455 0 0 0 0 9.4536 P47974 TISD_HUMAN "mRNA decay activator protein ZFP36L2 (Butyrate response factor 2) (EGF-response factor 2) (ERF-2) (TPA-induced sequence 11d) (Zinc finger protein 36, C3H1 type-like 2) (ZFP36-like 2)" ZFP36L2 ERF2 RNF162C TIS11D Homo sapiens (Human) "3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to tumor necrosis factor [GO:0071356]; definitive hemopoiesis [GO:0060216]; ERK1 and ERK2 cascade [GO:0070371]; hemopoiesis [GO:0030097]; mRNA catabolic process [GO:0006402]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of mitotic cell cycle phase transition [GO:1901991]; negative regulation of stem cell differentiation [GO:2000737]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; regulation of B cell differentiation [GO:0045577]; regulation of mRNA stability [GO:0043488]; response to wounding [GO:0009611]; somatic stem cell division [GO:0048103]; somatic stem cell population maintenance [GO:0035019]; T cell differentiation in thymus [GO:0033077]" cytoplasm [GO:0005737]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] metal ion binding [GO:0046872]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; RNA binding [GO:0003723] 0.95412 -1.5259 DRSFSENGDR 0 0 0 0 0 0 12.2458 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P47985 UCRI_HUMAN "Cytochrome b-c1 complex subunit Rieske, mitochondrial (EC 7.1.1.8) (Complex III subunit 5) (Cytochrome b-c1 complex subunit 5) (Rieske iron-sulfur protein) (RISP) (Rieske protein UQCRFS1) (Ubiquinol-cytochrome c reductase iron-sulfur subunit) [Cleaved into: Cytochrome b-c1 complex subunit 9 (Su9) (Subunit 9) (8 kDa subunit 9) (Complex III subunit IX) (Cytochrome b-c1 complex subunit 11) (UQCRFS1 mitochondrial targeting sequence) (UQCRFS1 MTS) (Ubiquinol-cytochrome c reductase 8 kDa protein)]" UQCRFS1 Homo sapiens (Human) "cellular respiration [GO:0045333]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]; respiratory electron transport chain [GO:0022904]" mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739] "2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; ubiquinol-cytochrome-c reductase activity [GO:0008121]" 0.0058651 2.3696 LEVLDSTKSSR 0 0 0 0 0 0 0 0 0 0 10.8126 0 0 0 0 0 0 10.3329 0 0 0 0 0 0 9.23264 0 0 P47989 XDH_HUMAN Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)] XDH XDHA Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; adenosine catabolic process [GO:0006154]; allantoin metabolic process [GO:0000255]; amide catabolic process [GO:0043605]; AMP catabolic process [GO:0006196]; dAMP catabolic process [GO:0046059]; deoxyadenosine catabolic process [GO:0006157]; deoxyguanosine catabolic process [GO:0006161]; deoxyinosine catabolic process [GO:0006149]; dGMP catabolic process [GO:0046055]; GMP catabolic process [GO:0046038]; guanine catabolic process [GO:0006147]; hypoxanthine catabolic process [GO:0009114]; IMP catabolic process [GO:0006204]; inosine catabolic process [GO:0006148]; iron-sulfur cluster assembly [GO:0016226]; lactation [GO:0007595]; negative regulation of endothelial cell differentiation [GO:0045602]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of gene expression [GO:0010629]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of vascular endothelial growth factor signaling pathway [GO:1900747]; negative regulation of vasculogenesis [GO:2001213]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; xanthine catabolic process [GO:0009115] cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; sarcoplasmic reticulum [GO:0016529] "2 iron, 2 sulfur cluster binding [GO:0051537]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; hypoxanthine dehydrogenase activity [GO:0070674]; hypoxanthine oxidase activity [GO:0070675]; iron ion binding [GO:0005506]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]" 0.96848 -3.8521 LDSPATPEK 0 0 10.2819 0 0 0 0 0 0 9.4672 9.35566 9.23266 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P48023 TNFL6_HUMAN "Tumor necrosis factor ligand superfamily member 6 (Apoptosis antigen ligand) (APTL) (CD95 ligand) (CD95-L) (Fas antigen ligand) (Fas ligand) (FasL) (CD antigen CD178) [Cleaved into: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form (Receptor-binding FasL ectodomain) (Soluble Fas ligand) (sFasL); ADAM10-processed FasL form (APL); FasL intracellular domain (FasL ICD) (SPPL2A-processed FasL form) (SPA)]" FASLG APT1LG1 CD95L FASL TNFSF6 Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cell-cell signaling [GO:0007267]; cellular response to type II interferon [GO:0071346]; endosomal lumen acidification [GO:0048388]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; inflammatory cell apoptotic process [GO:0006925]; intracellular chloride ion homeostasis [GO:0030644]; necroptotic process [GO:0070266]; necroptotic signaling pathway [GO:0097527]; negative regulation of angiogenesis [GO:0016525]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylserine exposure on apoptotic cell surface [GO:1905782]; release of sequestered calcium ion into cytosol by endoplasmic reticulum [GO:1903514]; response to growth factor [GO:0070848]; response to lipopolysaccharide [GO:0032496]; retinal cell programmed cell death [GO:0046666]; signal transduction [GO:0007165]; T cell apoptotic process [GO:0070231] caveola [GO:0005901]; cytoplasmic vesicle lumen [GO:0060205]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] cytokine activity [GO:0005125]; death receptor binding [GO:0005123]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164] 0.93299 -1.2659 ELRKVAHLTGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.23821 9.00433 9.17822 0 0 0 0 0 0 0 0 0 0 P48029 SC6A8_HUMAN Sodium- and chloride-dependent creatine transporter 1 (CT1) (Creatine transporter 1) (Solute carrier family 6 member 8) SLC6A8 Homo sapiens (Human) creatine metabolic process [GO:0006600]; creatine transmembrane transport [GO:0015881]; muscle contraction [GO:0006936]; neurotransmitter transport [GO:0006836]; nitrogen compound transport [GO:0071705]; sodium ion transmembrane transport [GO:0035725] apical plasma membrane [GO:0016324]; membrane [GO:0016020]; plasma membrane [GO:0005886] creatine transmembrane transporter activity [GO:0005308]; creatine:sodium symporter activity [GO:0005309] 0.82038 0.21944 SPVIEFWENK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.6601 0 0 0 0 0 0 0 P48047 ATPO_HUMAN "ATP synthase subunit O, mitochondrial (ATP synthase peripheral stalk subunit OSCP) (Oligomycin sensitivity conferral protein) (OSCP)" ATP5PO ATP5O ATPO Homo sapiens (Human) ATP biosynthetic process [GO:0006754]; proton motive force-driven ATP synthesis [GO:0015986]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]; proton transmembrane transport [GO:1902600] "mitochondrial inner membrane [GO:0005743]; mitochondrial proton-transporting ATP synthase complex [GO:0005753]; mitochondrial proton-transporting ATP synthase, stator stalk [GO:0000274]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]" "proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]" 0.005698 2.293 LVRPPVQVYGIEGR 0 0 0 0 0 0 0 8.91376 8.73867 0 0 0 0 0 0 0 0 0 0 9.82653 8.644 0 9.70491 0 0 0 0 P48052 CBPA2_HUMAN Carboxypeptidase A2 (EC 3.4.17.15) CPA2 Homo sapiens (Human) protein catabolic process in the vacuole [GO:0007039]; proteolysis [GO:0006508] extracellular region [GO:0005576]; extracellular space [GO:0005615]; vacuole [GO:0005773] carboxypeptidase activity [GO:0004180]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270] 0.56229 0.51008 AIMEHVR 0 9.69063 0 0 0 0 0 0 0 0 0 10.8809 0 0 0 0 9.51312 10.5572 0 0 0 0 0 0 10.1568 0 10.2514 P48058 GRIA4_HUMAN "Glutamate receptor 4 (GluR-4) (GluR4) (AMPA-selective glutamate receptor 4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (GluA4)" GRIA4 GLUR4 Homo sapiens (Human) "glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; synaptic transmission, glutamatergic [GO:0035249]" AMPA glutamate receptor complex [GO:0032281]; dendritic spine [GO:0043197]; endocytic vesicle membrane [GO:0030666]; extracellular vesicle [GO:1903561]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839] AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ionotropic glutamate receptor activity [GO:0004970]; ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315] 0.88347 -0.32118 KFVIDCEIER 8.7163 0 0 0 0 0 0 0 0 10.1537 10.5005 10.7567 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.6749 P48059 LIMS1_HUMAN LIM and senescent cell antigen-like-containing domain protein 1 (Particularly interesting new Cys-His protein 1) (PINCH-1) (Renal carcinoma antigen NY-REN-48) LIMS1 PINCH PINCH1 Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cell-cell junction organization [GO:0045216]; cellular response to transforming growth factor beta stimulus [GO:0071560]; establishment of protein localization [GO:0045184]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; tumor necrosis factor-mediated signaling pathway [GO:0033209] cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] protein kinase binding [GO:0019901]; zinc ion binding [GO:0008270] 0.91682 -0.84316 ELTADARELK 0 0 0 10.2932 0 0 0 0 0 0 0 11.1371 9.18656 9.37036 0 0 0 10.2268 0 0 0 0 0 0 0 0 0 P48061 SDF1_HUMAN Stromal cell-derived factor 1 (SDF-1) (hSDF-1) (C-X-C motif chemokine 12) (Intercrine reduced in hepatomas) (IRH) (hIRH) (Pre-B cell growth-stimulating factor) (PBSF) [Cleaved into: SDF-1-beta(3-72); SDF-1-alpha(3-67)] CXCL12 SDF1 SDF1A SDF1B Homo sapiens (Human) adult locomotory behavior [GO:0008344]; animal organ regeneration [GO:0031100]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; axon guidance [GO:0007411]; blood circulation [GO:0008015]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cellular response to chemokine [GO:1990869]; chemokine (C-X-C motif) ligand 12 signaling pathway [GO:0038146]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; defense response [GO:0006952]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; induction of positive chemotaxis [GO:0050930]; integrin activation [GO:0033622]; intracellular calcium ion homeostasis [GO:0006874]; killing of cells of another organism [GO:0031640]; negative regulation of dendritic cell apoptotic process [GO:2000669]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; negative regulation of leukocyte tethering or rolling [GO:1903237]; neuron migration [GO:0001764]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of calcium ion import [GO:0090280]; positive regulation of cell adhesion [GO:0045785]; positive regulation of dopamine secretion [GO:0033603]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of T cell migration [GO:2000406]; regulation of actin polymerization or depolymerization [GO:0008064]; response to heat [GO:0009408]; response to hypoxia [GO:0001666]; response to peptide hormone [GO:0043434]; response to radiation [GO:0009314]; response to ultrasound [GO:1990478]; response to virus [GO:0009615]; signal transduction [GO:0007165]; T cell chemotaxis [GO:0010818]; telencephalon cell migration [GO:0022029] collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleus [GO:0005634] chemokine activity [GO:0008009]; chemokine receptor binding [GO:0042379]; CXCR chemokine receptor binding [GO:0045236]; growth factor activity [GO:0008083]; integrin binding [GO:0005178]; signaling receptor binding [GO:0005102] 0.88592 -0.33204 QVCIDPKLK 0 0 0 0 0 0 0 0 8.99687 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P48067 SC6A9_HUMAN Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (Solute carrier family 6 member 9) SLC6A9 Homo sapiens (Human) "glycine import across plasma membrane [GO:1903804]; glycine transport [GO:0015816]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; neurotransmitter transport [GO:0006836]; positive regulation of heme biosynthetic process [GO:0070455]; positive regulation of hemoglobin biosynthetic process [GO:0046985]; regulation of synaptic transmission, glycinergic [GO:0060092]; sodium ion transmembrane transport [GO:0035725]; synaptic transmission, glycinergic [GO:0060012]; transport across blood-brain barrier [GO:0150104]" apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; dense core granule [GO:0031045]; endosome [GO:0005768]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; lateral plasma membrane [GO:0016328]; membrane [GO:0016020]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synaptic vesicle membrane [GO:0030672] glycine transmembrane transporter activity [GO:0015187]; glycine:sodium symporter activity [GO:0015375] 0.86299 0.087759 DWGPALLEHR 0 12.9887 0 0 0 0 0 0 0 0 0 0 0 12.78 0 0 0 8.58256 0 0 0 0 0 0 0 0 0 P48147 PPCE_HUMAN Prolyl endopeptidase (PE) (EC 3.4.21.26) (Post-proline cleaving enzyme) PREP PEP Homo sapiens (Human) proteolysis [GO:0006508] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634] oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236] 0.95832 -1.8679 GGILANK 9.75856 0 9.83306 0 0 0 15.4793 9.97857 9.96332 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P48163 MAOX_HUMAN NADP-dependent malic enzyme (NADP-ME) (EC 1.1.1.40) (Malic enzyme 1) ME1 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; NADP metabolic process [GO:0006739]; nucleotide biosynthetic process [GO:0009165]; protein homotetramerization [GO:0051289]; pyruvate metabolic process [GO:0006090]; regulation of NADP metabolic process [GO:1902031]; response to carbohydrate [GO:0009743]; response to hormone [GO:0009725] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739] ADP binding [GO:0043531]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; malate dehydrogenase (decarboxylating) (NADP+) activity [GO:0004473]; malic enzyme activity [GO:0004470]; manganese ion binding [GO:0030145]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxaloacetate decarboxylase activity [GO:0008948] 0.84196 0.17859 AIVVTDGER 0 0 0 0 0 0 0 0 9.86708 0 0 0 0 8.42538 8.68867 0 0 0 0 0 0 10.2427 0 0 10.9726 0 11.7368 P48165 CXA8_HUMAN Gap junction alpha-8 protein (Connexin-50) (Cx50) (Lens fiber protein MP70) GJA8 Homo sapiens (Human) cell-cell signaling [GO:0007267]; gap junction-mediated intercellular transport [GO:1990349]; lens development in camera-type eye [GO:0002088]; regulation of catalase activity [GO:1902551]; regulation of glutathione peroxidase activity [GO:1903282]; regulation of granulocyte macrophage colony-stimulating factor production [GO:0032645] connexin complex [GO:0005922]; plasma membrane [GO:0005886] gap junction channel activity [GO:0005243]; identical protein binding [GO:0042802] 0.95166 -1.4402 ILPLYRCSR 0 0 0 0 0 0 0 0 0 0 0 9.52362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P48167 GLRB_HUMAN Glycine receptor subunit beta (Glycine receptor 58 kDa subunit) GLRB Homo sapiens (Human) "acrosome reaction [GO:0007340]; adult walking behavior [GO:0007628]; chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid receptor clustering [GO:0097112]; monoatomic ion transport [GO:0006811]; nervous system development [GO:0007399]; nervous system process [GO:0050877]; neuropeptide signaling pathway [GO:0007218]; regulation of membrane potential [GO:0042391]; righting reflex [GO:0060013]; startle response [GO:0001964]; synaptic transmission, glycinergic [GO:0060012]; visual perception [GO:0007601]" cytoplasm [GO:0005737]; dendrite [GO:0030425]; GABA-ergic synapse [GO:0098982]; glycine-gated chloride channel complex [GO:0016935]; glycinergic synapse [GO:0098690]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; synapse [GO:0045202] extracellularly glycine-gated chloride channel activity [GO:0016934]; extracellularly glycine-gated ion channel activity [GO:0016933]; glycine binding [GO:0016594]; neurotransmitter receptor activity [GO:0030594]; protein-containing complex binding [GO:0044877]; transmembrane signaling receptor activity [GO:0004888]; transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315] 0.96441 -2.6855 KEDIEYGNCTKYYK 0 0 0 0 0 0 0 0 0 0 0 0 10.099 10.1346 0 0 0 0 0 0 0 0 10.3997 0 0 0 0 P48169 GBRA4_HUMAN Gamma-aminobutyric acid receptor subunit alpha-4 (GABA(A) receptor subunit alpha-4) GABRA4 Homo sapiens (Human) "chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; nervous system process [GO:0050877]; regulation of postsynaptic membrane potential [GO:0060078]; signal transduction [GO:0007165]; synaptic transmission, GABAergic [GO:0051932]" chloride channel complex [GO:0034707]; dendrite membrane [GO:0032590]; GABA-A receptor complex [GO:1902711]; GABA-ergic synapse [GO:0098982]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic specialization membrane [GO:0099634]; synapse [GO:0045202] benzodiazepine receptor activity [GO:0008503]; GABA-A receptor activity [GO:0004890]; GABA-gated chloride ion channel activity [GO:0022851]; inhibitory extracellular ligand-gated monoatomic ion channel activity [GO:0005237]; transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315] 0.88424 -0.2491 LNNMMVTK 11.4167 0 11.3232 0 0 0 0 0 0 12.9441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.69012 0 0 P48200 IREB2_HUMAN Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron regulatory protein 2) (IRP2) IREB2 Homo sapiens (Human) citrate metabolic process [GO:0006101]; erythrocyte homeostasis [GO:0034101]; establishment of localization in cell [GO:0051649]; intestinal absorption [GO:0050892]; intracellular iron ion homeostasis [GO:0006879]; mRNA stabilization [GO:0048255]; multicellular organismal-level iron ion homeostasis [GO:0060586]; osteoclast differentiation [GO:0030316]; post-embryonic development [GO:0009791]; protoporphyrinogen IX biosynthetic process [GO:0006782]; regulation of translation [GO:0006417]; tricarboxylic acid cycle [GO:0006099] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739] "4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; iron-responsive element binding [GO:0030350]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]" 0.89062 -0.49433 AVEAGLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5113 0 0 10.2341 0 0 0 0 11.0029 0 P48201 AT5G3_HUMAN "ATP synthase F(0) complex subunit C3, mitochondrial (ATP synthase lipid-binding protein) (ATP synthase membrane subunit c locus 3) (ATP synthase proteolipid P3) (ATP synthase proton-transporting mitochondrial F(0) complex subunit C3) (ATPase protein 9) (ATPase subunit c)" ATP5MC3 ATP5G3 Homo sapiens (Human) proton motive force-driven ATP synthesis [GO:0015986] "mitochondrial inner membrane [GO:0005743]; mitochondrial outer membrane [GO:0005741]; mitochondrial proton-transporting ATP synthase complex [GO:0005753]; mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) [GO:0000276]" lipid binding [GO:0008289]; proton transmembrane transporter activity [GO:0015078] 0.76296 0.28685 LACTPSLIR 0 0 10.0027 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P48307 TFPI2_HUMAN Tissue factor pathway inhibitor 2 (TFPI-2) (Placental protein 5) (PP5) TFPI2 Homo sapiens (Human) blood coagulation [GO:0007596]; cellular response to fluid shear stress [GO:0071498]; negative regulation of peptidase activity [GO:0010466] extracellular matrix [GO:0031012]; extracellular space [GO:0005615] extracellular matrix structural constituent [GO:0005201]; serine-type endopeptidase inhibitor activity [GO:0004867] 0.91769 -0.85324 IPSFCYSPKDEGLCSANVTR 0 13.4579 0 9.87791 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P48357 LEPR_HUMAN Leptin receptor (LEP-R) (HuB219) (OB receptor) (OB-R) (CD antigen CD295) LEPR DB OBR Homo sapiens (Human) angiogenesis [GO:0001525]; bone growth [GO:0098868]; cell surface receptor signaling pathway [GO:0007166]; cholesterol metabolic process [GO:0008203]; cytokine-mediated signaling pathway [GO:0019221]; energy homeostasis [GO:0097009]; energy reserve metabolic process [GO:0006112]; glial cell proliferation [GO:0014009]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glycogen metabolic process [GO:0005977]; leptin-mediated signaling pathway [GO:0033210]; multicellular organism development [GO:0007275]; negative regulation of autophagy [GO:0010507]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of hydrolase activity [GO:0051346]; phagocytosis [GO:0006909]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of protein phosphorylation [GO:0001934]; regulation of bone remodeling [GO:0046850]; regulation of feeding behavior [GO:0060259]; regulation of transport [GO:0051049]; response to leptin [GO:0044321]; sexual reproduction [GO:0019953]; T cell differentiation [GO:0030217]; transport across blood-brain barrier [GO:0150104] basolateral plasma membrane [GO:0016323]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; receptor complex [GO:0043235] cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; leptin receptor activity [GO:0038021]; transmembrane signaling receptor activity [GO:0004888] 0.8424 0.14936 KYYIHDHFIPIEK 10.2542 12.4463 11.933 0 0 0 0 0 10.9278 10.249 10.6716 11.1532 0 10.9268 0 0 0 0 0 0 0 0 0 0 0 10.2804 0 P48382 RFX5_HUMAN DNA-binding protein RFX5 (Regulatory factor X 5) RFX5 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96597 -2.7265 EAEDKIPLVPSK 0 8.47318 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P48444 COPD_HUMAN Coatomer subunit delta (Archain) (Delta-coat protein) (Delta-COP) ARCN1 COPD Homo sapiens (Human) "adult locomotory behavior [GO:0008344]; cerebellar Purkinje cell layer maturation [GO:0021691]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi localization [GO:0051645]; intracellular protein transport [GO:0006886]; pigmentation [GO:0043473]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]" COPI vesicle coat [GO:0030126]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; transport vesicle [GO:0030133] RNA binding [GO:0003723] 0.17891 0.96121 GVQLQTHPNVDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0997 0 0 10.0887 0 0 10.6773 0 P48449 LSS_HUMAN "Lanosterol synthase (EC 5.4.99.7) (2,3-epoxysqualene--lanosterol cyclase) (Oxidosqualene--lanosterol cyclase) (OSC) (hOSC)" LSS OSC Homo sapiens (Human) cholesterol biosynthetic process [GO:0006695]; regulation of protein stability [GO:0031647]; steroid biosynthetic process [GO:0006694]; triterpenoid biosynthetic process [GO:0016104] endoplasmic reticulum membrane [GO:0005789]; lipid droplet [GO:0005811]; membrane [GO:0016020] lanosterol synthase activity [GO:0000250] 0.62361 0.41501 ILGVGPDDPDLVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1481 0 0 0 0 0 10.06 0 0 0 0 0 0 P48454 PP2BC_HUMAN "Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calcineurin, testis-specific catalytic subunit) (Calmodulin-dependent calcineurin A subunit gamma isoform)" PPP3CC CALNA3 CNA3 Homo sapiens (Human) brain development [GO:0007420]; calcineurin-mediated signaling [GO:0097720]; calcineurin-NFAT signaling cascade [GO:0033173]; negative regulation of calcium ion import across plasma membrane [GO:1905949]; negative regulation of voltage-gated calcium channel activity [GO:1901386]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of calcium ion import across plasma membrane [GO:1905665]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; protein dephosphorylation [GO:0006470] calcineurin complex [GO:0005955]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; mitochondrion [GO:0005739]; presynapse [GO:0098793]; protein serine/threonine phosphatase complex [GO:0008287] calcium-dependent protein serine/threonine phosphatase activity [GO:0004723]; calmodulin binding [GO:0005516]; calmodulin-dependent protein phosphatase activity [GO:0033192]; metal ion binding [GO:0046872]; myosin phosphatase activity [GO:0017018] 0.56271 0.51327 EVFENGKPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0334 0 0 0 0 0 0 0 P48506 GSH1_HUMAN Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2) (GCS heavy chain) (Gamma-ECS) (Gamma-glutamylcysteine synthetase) GCLC GLCL GLCLC Homo sapiens (Human) aging [GO:0007568]; blood vessel diameter maintenance [GO:0097746]; cell redox homeostasis [GO:0045454]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to glucose stimulus [GO:0071333]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; cellular response to thyroxine stimulus [GO:0097069]; cysteine metabolic process [GO:0006534]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; L-ascorbic acid metabolic process [GO:0019852]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of hepatic stellate cell activation [GO:2000490]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of mitochondrial depolarization [GO:0051900]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to cadmium ion [GO:0046686]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to human chorionic gonadotropin [GO:0044752]; response to interleukin-1 [GO:0070555]; response to nitrosative stress [GO:0051409]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to xenobiotic stimulus [GO:0009410] cytosol [GO:0005829]; glutamate-cysteine ligase complex [GO:0017109]; mitochondrion [GO:0005739] ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate binding [GO:0016595]; glutamate-cysteine ligase activity [GO:0004357]; magnesium ion binding [GO:0000287]; protein-containing complex binding [GO:0044877] 0.88861 -0.43155 KDICKGGNAVVDGCGK 0 0 0 0 0 0 0 0 0 0 8.98071 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P48509 CD151_HUMAN CD151 antigen (GP27) (Membrane glycoprotein SFA-1) (Platelet-endothelial tetraspan antigen 3) (PETA-3) (Tetraspanin-24) (Tspan-24) (CD antigen CD151) CD151 TSPAN24 Homo sapiens (Human) "cell adhesion [GO:0007155]; positive regulation of cell migration [GO:0030335]; positive regulation of endocytosis [GO:0045807]; T cell proliferation [GO:0042098]; wound healing, spreading of cells [GO:0044319]" basement membrane [GO:0005604]; cell surface [GO:0009986]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; membrane [GO:0016020]; plasma membrane [GO:0005886] integrin binding [GO:0005178] 0.91654 -0.85068 GEFNEKK 0 0 9.42727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P48547 KCNC1_HUMAN Potassium voltage-gated channel subfamily C member 1 (NGK2) (Voltage-gated potassium channel subunit Kv3.1) (Voltage-gated potassium channel subunit Kv4) KCNC1 Homo sapiens (Human) cellular response to xenobiotic stimulus [GO:0071466]; cerebellum development [GO:0021549]; corpus callosum development [GO:0022038]; globus pallidus development [GO:0021759]; optic nerve development [GO:0021554]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; protein tetramerization [GO:0051262]; response to amine [GO:0014075]; response to auditory stimulus [GO:0010996]; response to fibroblast growth factor [GO:0071774]; response to light intensity [GO:0009642]; response to nerve growth factor [GO:1990089]; response to potassium ion [GO:0035864]; response to toxic substance [GO:0009636] axolemma [GO:0030673]; axon [GO:0030424]; calyx of Held [GO:0044305]; cell surface [GO:0009986]; dendrite membrane [GO:0032590]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; voltage-gated potassium channel complex [GO:0008076] delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; transmembrane transporter binding [GO:0044325]; voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential [GO:0099508]; voltage-gated potassium channel activity [GO:0005249] 0.92512 -0.98454 ADEFFFDRHPGVFAHILNYYR 0 0 0 0 9.81826 0 0 0 0 0 9.12918 0 0 10.5845 0 9.83988 0 0 0 0 0 0 0 0 0 0 0 P48549 KCNJ3_HUMAN "G protein-activated inward rectifier potassium channel 1 (GIRK-1) (Inward rectifier K(+) channel Kir3.1) (Potassium channel, inwardly rectifying subfamily J member 3)" KCNJ3 GIRK1 Homo sapiens (Human) membrane repolarization during atrial cardiac muscle cell action potential [GO:0098914]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transport [GO:0006813]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of monoatomic ion transmembrane transport [GO:0034765]; response to electrical stimulus [GO:0051602]; ventricular cardiac muscle cell membrane repolarization [GO:0099625] external side of plasma membrane [GO:0009897]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; T-tubule [GO:0030315]; voltage-gated potassium channel complex [GO:0008076] G-protein activated inward rectifier potassium channel activity [GO:0015467]; voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential [GO:0099508]; voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization [GO:0086089]; voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1902282] 0.96284 -2.5246 ITGREDFPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.70891 0 0 0 0 10.5343 0 11.1709 0 10.0486 P48552 NRIP1_HUMAN Nuclear receptor-interacting protein 1 (Nuclear factor RIP140) (Receptor-interacting protein 140) NRIP1 Homo sapiens (Human) cellular response to estradiol stimulus [GO:0071392]; circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; lipid storage [GO:0019915]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ovarian follicle rupture [GO:0001543]; positive regulation of transcription by RNA polymerase II [GO:0045944] chromatin [GO:0000785]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; histone deacetylase complex [GO:0000118]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] histone deacetylase binding [GO:0042826]; nuclear estrogen receptor binding [GO:0030331]; nuclear glucocorticoid receptor binding [GO:0035259]; nuclear receptor binding [GO:0016922]; nuclear retinoid X receptor binding [GO:0046965]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; signaling receptor binding [GO:0005102]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714] 0.96962 -3.9656 GGNSVTSRETQDK 0 0 0 0 0 0 0 0 0 0 9.98057 0 0 0 0 0 0 0 0 0 0 0 0 9.40175 0 0 0 P48553 TPC10_HUMAN Trafficking protein particle complex subunit 10 (Epilepsy holoprosencephaly candidate 1 protein) (EHOC-1) (Protein GT334) (Trafficking protein particle complex subunit TMEM1) (Transport protein particle subunit TMEM1) (TRAPP subunit TMEM1) TRAPPC10 EHOC1 TMEM1 Homo sapiens (Human) early endosome to Golgi transport [GO:0034498]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; vesicle coating [GO:0006901]; vesicle tethering [GO:0099022] cytoplasm [GO:0005737]; cytosol [GO:0005829]; TRAPP complex [GO:0030008]; TRAPPII protein complex [GO:1990071] 0.14335 1.027 EALSSVEAFEK 0 0 0 0 0 0 0 0 0 9.87785 0 11.3194 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P48634 PRC2A_HUMAN Protein PRRC2A (HLA-B-associated transcript 2) (Large proline-rich protein BAT2) (Proline-rich and coiled-coil-containing protein 2A) (Protein G2) PRRC2A BAT2 G2 Homo sapiens (Human) cell differentiation [GO:0030154] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] RNA binding [GO:0003723] 0.96946 -6.4637 FPRVAGPR 0 9.28824 0 10.0897 0 0 0 0 0 0 0 0 0 0 0 0 9.55505 0 0 0 0 0 0 0 0 0 0 P48637 GSHB_HUMAN Glutathione synthetase (GSH synthetase) (GSH-S) (EC 6.3.2.3) (Glutathione synthase) GSS Homo sapiens (Human) amino acid metabolic process [GO:0006520]; nervous system development [GO:0007399]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979] cytosol [GO:0005829]; extracellular exosome [GO:0070062] ATP binding [GO:0005524]; glutathione binding [GO:0043295]; glutathione synthase activity [GO:0004363]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803] 0.005814 2.3381 AIEHADGGVAAGVAVLDNPYPV 0 0 0 0 0 0 0 0 9.81625 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8376 10.0729 P48643 TCPE_HUMAN T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) CCT5 CCTE KIAA0098 Homo sapiens (Human) binding of sperm to zona pellucida [GO:0007339]; chaperone-mediated protein folding [GO:0061077]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of protein localization to Cajal body [GO:1904871]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; response to virus [GO:0009615]; toxin transport [GO:1901998] cell body [GO:0044297]; centrosome [GO:0005813]; chaperonin-containing T-complex [GO:0005832]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; beta-tubulin binding [GO:0048487]; G-protein beta-subunit binding [GO:0031681]; mRNA 3'-UTR binding [GO:0003730]; mRNA 5'-UTR binding [GO:0048027]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082] 0 3.9709 FSELTAEK 0 10.608 0 0 0 0 11.0008 9.50428 11.1499 10.4029 9.35742 10.7058 0 0 0 0 9.37306 9.78234 9.36759 9.51779 0 0 0 0 0 0 0 P48651 PTSS1_HUMAN Phosphatidylserine synthase 1 (PSS-1) (PtdSer synthase 1) (EC 2.7.8.29) (Serine-exchange enzyme I) PTDSS1 KIAA0024 PSSA Homo sapiens (Human) phosphatidylserine biosynthetic process [GO:0006659] endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] L-serine-phosphatidylcholine phosphatidyltransferase activity [GO:0106258]; L-serine-phosphatidylethanolamine phosphatidyltransferase activity [GO:0106245]; transferase activity [GO:0016740] 0.8073 0.23475 TYHWASFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.63465 0 0 0 0 0 0 0 P48668 K2C6C_HUMAN "Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK-6C) (Cytokeratin-6E) (CK-6E) (Keratin K6h) (Keratin-6C) (K6C) (Type-II keratin Kb12)" KRT6C KRT6E Homo sapiens (Human) intermediate filament cytoskeleton organization [GO:0045104]; keratinization [GO:0031424] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; keratin filament [GO:0045095] structural constituent of skin epidermis [GO:0030280] 0.00625 2.7342 ADTLTDEINFLR 10.6935 10.4509 10.5782 0 0 0 10.1134 10.2394 10.2899 9.68822 10.0701 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.37762 P48681 NEST_HUMAN Nestin NES Nbla00170 Homo sapiens (Human) brain development [GO:0007420]; cell projection morphogenesis [GO:0048858]; central nervous system development [GO:0007417]; embryonic camera-type eye development [GO:0031076]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of catalytic activity [GO:0043086]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; neuron apoptotic process [GO:0051402]; positive regulation of intermediate filament depolymerization [GO:0030844]; positive regulation of neural precursor cell proliferation [GO:2000179]; stem cell proliferation [GO:0072089] cytoplasm [GO:0005737]; intermediate filament [GO:0005882]; intermediate filament cytoskeleton [GO:0045111] CCR5 chemokine receptor binding [GO:0031730]; intermediate filament binding [GO:0019215] 0.96964 -3.306 CQQLRLARER 11.9686 0 0 10.5837 0 11.5988 0 0 0 14.227 14.1156 13.6847 0 9.86963 0 0 11.6796 0 9.00935 8.7386 0 0 9.14354 0 0 0 0 P48723 HSP13_HUMAN Heat shock 70 kDa protein 13 (Microsomal stress-70 protein ATPase core) (Stress-70 protein chaperone microsome-associated 60 kDa protein) HSPA13 STCH Homo sapiens (Human) chaperone cofactor-dependent protein refolding [GO:0051085]; protein refolding [GO:0042026] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; heat shock protein binding [GO:0031072]; protein folding chaperone [GO:0044183] 0.8416 0.18192 LSSADDHR 0 8.71908 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P48729 KC1A_HUMAN Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1) CSNK1A1 Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; cell surface receptor signaling pathway [GO:0007166]; Golgi organization [GO:0007030]; intermediate filament cytoskeleton organization [GO:0045104]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein phosphorylation [GO:0006468]; regulation of GTP binding [GO:1904424]; signal transduction [GO:0007165]; viral protein processing [GO:0019082]; Wnt signaling pathway [GO:0016055] beta-catenin destruction complex [GO:0030877]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cilium [GO:0005929]; cytosol [GO:0005829]; kinetochore [GO:0000776]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; spindle [GO:0005819] ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.9141 -0.81894 ASSSGSK 0 0 0 0 0 0 0 0 0 0 0 8.43212 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P48730 KC1D_HUMAN Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein kinase CSNK1D) (EC 2.7.11.26) CSNK1D HCKID Homo sapiens (Human) cellular response to nerve growth factor stimulus [GO:1990090]; circadian regulation of gene expression [GO:0032922]; COPII vesicle coating [GO:0048208]; endocytosis [GO:0006897]; Golgi organization [GO:0007030]; microtubule nucleation [GO:0007020]; non-motile cilium assembly [GO:1905515]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of non-canonical Wnt signaling pathway [GO:2000052]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation [GO:1905426]; protein localization to centrosome [GO:0071539]; protein localization to cilium [GO:0061512]; protein localization to Golgi apparatus [GO:0034067]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; signal transduction [GO:0007165]; spindle assembly [GO:0051225]; Wnt signaling pathway [GO:0016055] centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytosol [GO:0005829]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; Golgi apparatus [GO:0005794]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; spindle [GO:0005819]; spindle microtubule [GO:0005876] ATP binding [GO:0005524]; cadherin binding [GO:0045296]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; tau-protein kinase activity [GO:0050321] 0.90574 -0.72823 TKHPQLHIESK 0 0 0 0 0 9.98071 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P48735 IDHP_HUMAN "Isocitrate dehydrogenase [NADP], mitochondrial (IDH) (EC 1.1.1.42) (ICD-M) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase)" IDH2 Homo sapiens (Human) 2-oxoglutarate metabolic process [GO:0006103]; carbohydrate metabolic process [GO:0005975]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; tricarboxylic acid cycle [GO:0006099] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisome [GO:0005777] isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287] 0 5.7716 ATDFVADR 0 0 0 0 0 0 8.37513 8.49333 8.42626 10.5283 0 0 8.75572 8.98456 9.12536 9.90665 9.28628 8.90298 0 0 8.44907 0 0 0 0 9.86592 0 P48736 PK3CG_HUMAN "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) (PI3K-gamma) (PI3Kgamma) (PtdIns-3-kinase subunit gamma) (EC 2.7.1.137) (EC 2.7.1.153) (EC 2.7.1.154) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma) (PtdIns-3-kinase subunit p110-gamma) (p110gamma) (Phosphoinositide-3-kinase catalytic gamma polypeptide) (Serine/threonine protein kinase PIK3CG) (EC 2.7.11.1) (p120-PI3K)" PIK3CG Homo sapiens (Human) adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; cell migration [GO:0016477]; cellular response to cAMP [GO:0071320]; dendritic cell chemotaxis [GO:0002407]; endocytosis [GO:0006897]; G protein-coupled receptor signaling pathway [GO:0007186]; hepatocyte apoptotic process [GO:0097284]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; mast cell degranulation [GO:0043303]; natural killer cell chemotaxis [GO:0035747]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of fibroblast apoptotic process [GO:2000270]; negative regulation of triglyceride catabolic process [GO:0010897]; neutrophil chemotaxis [GO:0030593]; neutrophil extravasation [GO:0072672]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; phosphorylation [GO:0016310]; platelet aggregation [GO:0070527]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Rac protein signal transduction [GO:0035022]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of calcium ion transmembrane transport [GO:1903169]; regulation of cell adhesion mediated by integrin [GO:0033628]; respiratory burst involved in defense response [GO:0002679]; secretory granule localization [GO:0032252]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; T cell activation [GO:0042110]; T cell chemotaxis [GO:0010818]; T cell proliferation [GO:0042098] "cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; phosphatidylinositol 3-kinase complex, class IA [GO:0005943]; phosphatidylinositol 3-kinase complex, class IB [GO:0005944]; plasma membrane [GO:0005886]" "1-phosphatidylinositol-3-kinase activity [GO:0016303]; 1-phosphatidylinositol-4-phosphate 3-kinase activity [GO:0035005]; ATP binding [GO:0005524]; ephrin receptor binding [GO:0046875]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; phosphatidylinositol 3-kinase activity [GO:0035004]; phosphatidylinositol-3,4-bisphosphate 5-kinase activity [GO:0052812]; phosphatidylinositol-4,5-bisphosphate 3-kinase activity [GO:0046934]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]" 0.89853 -0.65313 KGQWYEIYDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.96691 P48739 PIPNB_HUMAN Phosphatidylinositol transfer protein beta isoform (PI-TP-beta) (PtdIns transfer protein beta) (PtdInsTP beta) PITPNB Homo sapiens (Human) "lipid metabolic process [GO:0006629]; nucleus organization [GO:0006997]; phospholipid transport [GO:0015914]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]" cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139] phosphatidylcholine binding [GO:0031210]; phosphatidylcholine transfer activity [GO:0120019]; phosphatidylcholine transporter activity [GO:0008525]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol transfer activity [GO:0008526]; sphingomyelin transfer activity [GO:0140338] 0.83648 0.19315 WWGLQSK 0 0 0 0 0 0 12.5386 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P48745 CCN3_HUMAN CCN family member 3 (Cellular communication network factor 3) (Insulin-like growth factor-binding protein 9) (IBP-9) (IGF-binding protein 9) (IGFBP-9) (Nephro blastoma-overexpressed gene protein homolog) (Protein NOV homolog) (NovH) CCN3 IGFBP9 NOV NOVH Homo sapiens (Human) angiogenesis [GO:0001525]; bone regeneration [GO:1990523]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell chemotaxis [GO:0060326]; chondrocyte differentiation [GO:0002062]; endothelial cell chemotaxis [GO:0035767]; endothelial cell-cell adhesion [GO:0071603]; fibroblast migration [GO:0010761]; hematopoietic stem cell homeostasis [GO:0061484]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of chondrocyte proliferation [GO:1902731]; negative regulation of inflammatory response [GO:0050728]; negative regulation of insulin secretion [GO:0046676]; negative regulation of monocyte chemotaxis [GO:0090027]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of sensory perception of pain [GO:1904057]; negative regulation of SMAD protein signal transduction [GO:0060392]; positive regulation of Notch signaling pathway [GO:0045747]; regulation of gene expression [GO:0010468]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]; smooth muscle cell proliferation [GO:0048659]; type B pancreatic cell proliferation [GO:0044342] axon [GO:0030424]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; gap junction [GO:0005921]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025] growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; Notch binding [GO:0005112] 0.88351 -0.10959 LCMVRPCEQEPEQPTDKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.80842 0 0 0 0 P48764 SL9A3_HUMAN Sodium/hydrogen exchanger 3 (Na(+)/H(+) exchanger 3) (NHE-3) (Solute carrier family 9 member 3) SLC9A3 NHE3 Homo sapiens (Human) monoatomic ion transport [GO:0006811]; potassium ion transmembrane transport [GO:0071805]; regulation of intracellular pH [GO:0051453]; sodium ion import across plasma membrane [GO:0098719] apical plasma membrane [GO:0016324]; brush border [GO:0005903]; brush border membrane [GO:0031526]; cell surface [GO:0009986]; early endosome [GO:0005769]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038] identical protein binding [GO:0042802]; PDZ domain binding [GO:0030165]; phosphatidylinositol binding [GO:0035091]; potassium:proton antiporter activity [GO:0015386]; sodium:proton antiporter activity [GO:0015385] 0.7684 0.27674 LGLNQNK 0 0 0 0 0 0 0 0 0 0 0 9.09273 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P48775 T23O_HUMAN "Tryptophan 2,3-dioxygenase (TDO) (EC 1.13.11.11) (Tryptamin 2,3-dioxygenase) (Tryptophan oxygenase) (TO) (TRPO) (Tryptophan pyrrolase) (Tryptophanase)" TDO2 TDO Homo sapiens (Human) protein homotetramerization [GO:0051289]; response to nitroglycerin [GO:1904842]; tryptophan catabolic process to acetyl-CoA [GO:0019442]; tryptophan catabolic process to kynurenine [GO:0019441] cytosol [GO:0005829] "amino acid binding [GO:0016597]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; tryptophan 2,3-dioxygenase activity [GO:0004833]" 0.84364 0.15205 SQTGVNR 0 0 10.0639 0 0 0 0 0 0 0 0 11.2153 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P49005 DPOD2_HUMAN DNA polymerase delta subunit 2 (DNA polymerase delta subunit p50) POLD2 Homo sapiens (Human) DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; DNA strand elongation involved in DNA replication [GO:0006271]; DNA-templated DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276] delta DNA polymerase complex [GO:0043625]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; zeta DNA polymerase complex [GO:0016035] DNA binding [GO:0003677] 0.82913 0.20555 AHTLLSPPSANNATFAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.037 0 0 0 0 0 0 0 0 0 P49006 MRP_HUMAN MARCKS-related protein (MARCKS-like protein 1) (Macrophage myristoylated alanine-rich C kinase substrate) (Mac-MARCKS) (MacMARCKS) MARCKSL1 MLP MRP Homo sapiens (Human) actin filament organization [GO:0007015]; cell population proliferation [GO:0008283]; central nervous system development [GO:0007417]; positive regulation of cell population proliferation [GO:0008284] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] actin filament binding [GO:0051015]; calmodulin binding [GO:0005516] 0.96422 -2.268 KPFKLSGLSFK 0 0 0 0 0 0 0 8.91489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6466 0 P49023 PAXI_HUMAN Paxillin PXN Homo sapiens (Human) cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to reactive oxygen species [GO:0034614]; endothelial cell migration [GO:0043542]; growth hormone receptor signaling pathway [GO:0060396]; positive regulation of stress fiber assembly [GO:0051496]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; substrate adhesion-dependent cell spreading [GO:0034446]; transforming growth factor beta receptor signaling pathway [GO:0007179] cell cortex [GO:0005938]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microtubule associated complex [GO:0005875]; plasma membrane [GO:0005886]; stress fiber [GO:0001725] beta-catenin binding [GO:0008013]; metal ion binding [GO:0046872]; neuropilin binding [GO:0038191]; protein phosphatase binding [GO:0019903]; vinculin binding [GO:0017166] 0.95367 -1.5251 CWAAGWPRDGGR 0 0 0 0 0 0 0 0 0 10.0807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P49137 MAPK2_HUMAN MAP kinase-activated protein kinase 2 (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAP-K2) (MAPKAPK-2) (MK-2) (MK2) (EC 2.7.11.1) MAPKAPK2 Homo sapiens (Human) 3'-UTR-mediated mRNA stabilization [GO:0070935]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; DNA damage response [GO:0006974]; inflammatory response [GO:0006954]; inner ear development [GO:0048839]; intracellular signal transduction [GO:0035556]; leukotriene metabolic process [GO:0006691]; macropinocytosis [GO:0044351]; MAPK cascade [GO:0000165]; p38MAPK cascade [GO:0038066]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of tumor necrosis factor production [GO:0032760]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cellular response to heat [GO:1900034]; regulation of interleukin-6 production [GO:0032675]; regulation of mRNA stability [GO:0043488]; regulation of tumor necrosis factor production [GO:0032680]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to cytokine [GO:0034097]; response to lipopolysaccharide [GO:0032496]; toll-like receptor signaling pathway [GO:0002224]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; calcium-dependent protein serine/threonine kinase activity [GO:0009931]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; mitogen-activated protein kinase binding [GO:0051019]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.92448 -1.0014 ALEAAALAH 0 0 0 0 0 0 0 0 0 0 0 9.59818 0 0 0 0 0 0 0 0 9.00492 0 0 0 0 0 0 P49189 AL9A1_HUMAN "4-trimethylaminobutyraldehyde dehydrogenase (TMABA-DH) (TMABALDH) (EC 1.2.1.47) (Aldehyde dehydrogenase E3 isozyme) (Aldehyde dehydrogenase family 9 member A1) (EC 1.2.1.3) (Gamma-aminobutyraldehyde dehydrogenase) (EC 1.2.1.19) (R-aminobutyraldehyde dehydrogenase) [Cleaved into: 4-trimethylaminobutyraldehyde dehydrogenase, N-terminally processed]" ALDH9A1 ALDH4 ALDH7 ALDH9 Homo sapiens (Human) carnitine biosynthetic process [GO:0045329]; cellular aldehyde metabolic process [GO:0006081]; hormone metabolic process [GO:0042445]; neurotransmitter biosynthetic process [GO:0042136]; protein homotetramerization [GO:0051289] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062] 1-pyrroline dehydrogenase activity [GO:0033737]; 4-trimethylammoniobutyraldehyde dehydrogenase activity [GO:0047105]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; small molecule binding [GO:0036094] 0 5.0654 EVNLAVQNAK 0 0 0 0 0 0 9.03136 0 8.89555 8.65721 0 0 0 10.4262 0 10.9025 0 0 0 0 9.46769 10.6258 0 0 0 0 0 P49207 RL34_HUMAN Large ribosomal subunit protein eL34 (60S ribosomal protein L34) RPL34 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleolus [GO:0005730]; synapse [GO:0045202] cadherin binding [GO:0045296]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.0061162 2.588 AFLIEEQK 0 0 0 0 0 0 9.84783 9.33818 9.5731 0 10.3387 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P49257 LMAN1_HUMAN Protein ERGIC-53 (ER-Golgi intermediate compartment 53 kDa protein) (Gp58) (Intracellular mannose-specific lectin MR60) (Lectin mannose-binding 1) LMAN1 ERGIC53 F5F8D Homo sapiens (Human) blood coagulation [GO:0007596]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; negative regulation of protein targeting to mitochondrion [GO:1903215]; positive regulation of organelle organization [GO:0010638]; protein folding [GO:0006457]; protein transport [GO:0015031] collagen-containing extracellular matrix [GO:0062023]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; sarcomere [GO:0030017] mannose binding [GO:0005537]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082] 0.0098039 1.8172 DIDNLVQR 0 0 9.22366 0 0 0 0 8.77979 9.45471 0 0 0 0 0 0 0 0 0 9.71273 0 0 0 0 0 0 0 0 P49281 NRAM2_HUMAN Natural resistance-associated macrophage protein 2 (NRAMP 2) (Divalent cation transporter 1) (Divalent metal transporter 1) (DMT-1) (Solute carrier family 11 member 2) SLC11A2 DCT1 DMT1 NRAMP2 OK/SW-cl.20 Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cadmium ion transmembrane transport [GO:0070574]; cellular response to oxidative stress [GO:0034599]; cobalt ion transport [GO:0006824]; copper ion transport [GO:0006825]; dendrite morphogenesis [GO:0048813]; detection of oxygen [GO:0003032]; erythrocyte development [GO:0048821]; heme biosynthetic process [GO:0006783]; intracellular iron ion homeostasis [GO:0006879]; iron import into cell [GO:0033212]; iron ion transmembrane transport [GO:0034755]; iron ion transport [GO:0006826]; lead ion transport [GO:0015692]; learning or memory [GO:0007611]; manganese ion transport [GO:0006828]; multicellular organismal-level iron ion homeostasis [GO:0060586]; nickel cation transport [GO:0015675]; response to hypoxia [GO:0001666]; response to iron ion [GO:0010039]; vanadium ion transport [GO:0015676] apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; extracellular vesicle [GO:1903561]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; paraferritin complex [GO:0070826]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; trans-Golgi network [GO:0005802]; vacuole [GO:0005773] cadmium ion binding [GO:0046870]; cadmium ion transmembrane transporter activity [GO:0015086]; cobalt ion transmembrane transporter activity [GO:0015087]; copper ion transmembrane transporter activity [GO:0005375]; ferrous iron transmembrane transporter activity [GO:0015093]; inorganic cation transmembrane transporter activity [GO:0022890]; iron ion transmembrane transporter activity [GO:0005381]; lead ion transmembrane transporter activity [GO:0015094]; manganese ion transmembrane transporter activity [GO:0005384]; nickel cation transmembrane transporter activity [GO:0015099]; retromer complex binding [GO:1905394]; solute:proton symporter activity [GO:0015295]; transition metal ion transmembrane transporter activity [GO:0046915]; vanadium ion transmembrane transporter activity [GO:0015100]; zinc ion transmembrane transporter activity [GO:0005385] 0.91389 -0.79808 ISIPEEEYSCFSFRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.32811 9.28799 P49321 NASP_HUMAN Nuclear autoantigenic sperm protein (NASP) NASP Homo sapiens (Human) blastocyst development [GO:0001824]; cell cycle [GO:0007049]; CENP-A containing chromatin assembly [GO:0034080]; DNA replication [GO:0006260]; DNA replication-dependent chromatin assembly [GO:0006335]; male gonad development [GO:0008584]; nucleosome assembly [GO:0006334]; protein transport [GO:0015031]; response to testosterone [GO:0033574] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] histone binding [GO:0042393]; protein-containing complex binding [GO:0044877] 0.56093 0.5322 MAVLNEQVK 0 0 9.15406 0 0 0 0 8.99794 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P49326 FMO5_HUMAN Flavin-containing monooxygenase 5 (FMO 5) (Baeyer-Villiger monooxygenase 1) (hBVMO1) (EC 1.14.13.-) (Dimethylaniline monooxygenase [N-oxide-forming] 5) (EC 1.14.13.8) (Dimethylaniline oxidase 5) (NADPH oxidase) (EC 1.6.3.1) FMO5 Homo sapiens (Human) lipid metabolic process [GO:0006629]; NADPH oxidation [GO:0070995]; regulation of cholesterol metabolic process [GO:0090181]; xenobiotic metabolic process [GO:0006805] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789] "aldehyde oxidase activity [GO:0004031]; flavin adenine dinucleotide binding [GO:0050660]; hypotaurine dehydrogenase activity [GO:0047822]; monooxygenase activity [GO:0004497]; N,N-dimethylaniline monooxygenase activity [GO:0004499]; NADP binding [GO:0050661]; NADPH oxidase H202-forming activity [GO:0106294]" 0.34673 0.76994 IISGLVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9541 0 0 0 0 0 P49327 FAS_HUMAN Fatty acid synthase (EC 2.3.1.85) (Type I fatty acid synthase) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Acyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)] FASN FAS Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; establishment of endothelial intestinal barrier [GO:0090557]; ether lipid biosynthetic process [GO:0008611]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]; glandular epithelial cell development [GO:0002068]; inflammatory response [GO:0006954]; mammary gland development [GO:0030879]; modulation by host of viral process [GO:0044788]; monocyte differentiation [GO:0030224]; neutrophil differentiation [GO:0030223]; osteoblast differentiation [GO:0001649] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glycogen granule [GO:0042587]; Golgi apparatus [GO:0005794]; melanosome [GO:0042470]; membrane [GO:0016020]; plasma membrane [GO:0005886] "(3R)-3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; (3R)-3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; (3R)-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity [GO:0004317]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; [acyl-carrier-protein] S-acetyltransferase activity [GO:0004313]; [acyl-carrier-protein] S-malonyltransferase activity [GO:0004314]; cadherin binding [GO:0045296]; enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity [GO:0047117]; fatty acid synthase activity [GO:0004312]; myristoyl-[acyl-carrier-protein] hydrolase activity [GO:0016295]; oleoyl-[acyl-carrier-protein] hydrolase activity [GO:0004320]; palmitoyl-[acyl-carrier-protein] hydrolase activity [GO:0016296]; phosphopantetheine binding [GO:0031177]; RNA binding [GO:0003723]" 0 256.35 AAAYRDRDSQR 12.4629 12.7505 12.4009 9.78229 10.6554 10.053 16.0093 15.4778 15.4708 11.3472 11.2815 11.4659 12.9358 13.1287 13.1063 13.5998 13.7616 13.3177 11.3088 11.9732 10.3484 11.3275 11.253 12.1743 13.5981 14.0121 13.5322 P49354 FNTA_HUMAN Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha) FNTA Homo sapiens (Human) neurotransmitter receptor metabolic process [GO:0045213]; positive regulation of deacetylase activity [GO:0090045]; positive regulation of tubulin deacetylation [GO:0090044]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; transforming growth factor beta receptor signaling pathway [GO:0007179] CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; microtubule associated complex [GO:0005875]; plasma membrane [GO:0005886]; protein farnesyltransferase complex [GO:0005965] acetylcholine receptor regulator activity [GO:0030548]; alpha-tubulin binding [GO:0043014]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; microtubule binding [GO:0008017]; molecular adaptor activity [GO:0060090]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; Rab geranylgeranyltransferase activity [GO:0004663]; receptor tyrosine kinase binding [GO:0030971] 0.87144 0.029738 DLHEEMNYITAIIEEQPK 12.3508 0 0 10.832 0 0 0 12.3615 12.4288 0 0 0 0 0 0 11.3892 0 0 0 0 0 9.26334 0 0 0 0 0 P49356 FNTB_HUMAN Protein farnesyltransferase subunit beta (FTase-beta) (EC 2.5.1.58) (CAAX farnesyltransferase subunit beta) (Ras proteins prenyltransferase subunit beta) FNTB Homo sapiens (Human) lipid metabolic process [GO:0006629]; protein farnesylation [GO:0018343] cytosol [GO:0005829]; microtubule associated complex [GO:0005875]; protein farnesyltransferase complex [GO:0005965] protein farnesyltransferase activity [GO:0004660]; zinc ion binding [GO:0008270] 0.9413 -1.3127 LVLQREKHFHYLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14.1699 0 0 0 0 0 0 0 0 0 0 0 0 P49368 TCPG_HUMAN T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (hTRiC5) CCT3 CCTG TRIC5 Homo sapiens (Human) binding of sperm to zona pellucida [GO:0007339]; chaperone-mediated protein folding [GO:0061077]; pore complex assembly [GO:0046931]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of protein localization to Cajal body [GO:1904871]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; toxin transport [GO:1901998] cell body [GO:0044297]; chaperonin-containing T-complex [GO:0005832]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]; zona pellucida receptor complex [GO:0002199] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082] 0 12.506 AVAQALEVIPR 8.97189 8.86833 9.08844 0 9.32474 0 0 0 9.1281 12.3464 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6479 P49406 RM19_HUMAN "Large ribosomal subunit protein bL19m (39S ribosomal protein L15, mitochondrial) (L15mt) (MRP-L15) (39S ribosomal protein L19, mitochondrial) (L19mt) (MRP-L19)" MRPL19 KIAA0104 MRPL15 Homo sapiens (Human) mitochondrial translation [GO:0032543] mitochondrial inner membrane [GO:0005743]; mitochondrial large ribosomal subunit [GO:0005762]; mitochondrion [GO:0005739]; nucleus [GO:0005634] structural constituent of ribosome [GO:0003735] 0.80839 0.22862 TLLPPPASIACR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.6776 0 0 P49407 ARRB1_HUMAN Beta-arrestin-1 (Arrestin beta-1) (Non-visual arrestin-2) ARRB1 ARR1 Homo sapiens (Human) G protein-coupled receptor internalization [GO:0002031]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of histone acetylation [GO:0035066]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; stress fiber assembly [GO:0043149]; ubiquitin-dependent protein catabolic process [GO:0006511]; visual perception [GO:0007601] chromatin [GO:0000785]; clathrin-coated pit [GO:0005905]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; lysosomal membrane [GO:0005765]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143] angiotensin receptor binding [GO:0031701]; arrestin family protein binding [GO:1990763]; enzyme inhibitor activity [GO:0004857]; G protein-coupled receptor binding [GO:0001664]; GTPase activator activity [GO:0005096]; insulin-like growth factor receptor binding [GO:0005159]; transcription coactivator activity [GO:0003713]; ubiquitin protein ligase binding [GO:0031625] 0.88983 -0.47417 KASPNGK 0 0 0 13.2844 13.4429 13.2434 10.7386 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P49411 EFTU_HUMAN "Elongation factor Tu, mitochondrial (EF-Tu) (P43)" TUFM Homo sapiens (Human) mitochondrial translational elongation [GO:0070125]; response to ethanol [GO:0045471]; translational elongation [GO:0006414] extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial nucleoid [GO:0042645]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; synapse [GO:0045202] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; RNA binding [GO:0003723]; translation elongation factor activity [GO:0003746] 0 17.425 AEAGDNLGALVR 10.7522 9.88557 10.5826 0 0 0 0 9.77624 0 10.1548 0 9.36685 9.46938 10.4964 11.1161 9.7493 11.8445 11.7614 10.9022 11.3448 10.89 9.45613 10.5305 11.3975 12.6579 12.0039 11.9851 P49450 CENPA_HUMAN Histone H3-like centromeric protein A (Centromere autoantigen A) (Centromere protein A) (CENP-A) CENPA Homo sapiens (Human) "CENP-A containing chromatin assembly [GO:0034080]; establishment of mitotic spindle orientation [GO:0000132]; kinetochore assembly [GO:0051382]; mitotic cytokinesis [GO:0000281]; protein localization to CENP-A containing chromatin [GO:0061644]; protein localization to chromosome, centromeric region [GO:0071459]" "CENP-A containing nucleosome [GO:0043505]; chromosome, centromeric region [GO:0000775]; condensed chromosome, centromeric region [GO:0000779]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]" chromatin binding [GO:0003682]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; structural constituent of chromatin [GO:0030527] 0.9462 -1.3499 RRQGWLK 0 0 0 0 0 11.8131 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P49454 CENPF_HUMAN Centromere protein F (CENP-F) (AH antigen) (Kinetochore protein CENPF) (Mitosin) CENPF Homo sapiens (Human) cell differentiation [GO:0030154]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; DNA biosynthetic process [GO:0071897]; kidney development [GO:0001822]; kinetochore assembly [GO:0051382]; metaphase plate congression [GO:0051310]; mitotic cell cycle [GO:0000278]; mitotic spindle assembly checkpoint signaling [GO:0007094]; muscle organ development [GO:0007517]; negative regulation of DNA-templated transcription [GO:0045892]; protein transport [GO:0015031]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of striated muscle tissue development [GO:0016202]; response to xenobiotic stimulus [GO:0009410]; ventricular system development [GO:0021591] "axoneme [GO:0005930]; centrosome [GO:0005813]; chromosome, centromeric region [GO:0000775]; ciliary basal body [GO:0036064]; ciliary transition fiber [GO:0097539]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; outer kinetochore [GO:0000940]; perinuclear region of cytoplasm [GO:0048471]; pronucleus [GO:0045120]; spindle [GO:0005819]; spindle pole [GO:0000922]" chromatin binding [GO:0003682]; DNA-binding transcription factor binding [GO:0140297]; dynein complex binding [GO:0070840]; microtubule binding [GO:0008017]; protein homodimerization activity [GO:0042803] 0.96928 -7.2545 EINASLNQEK 11.4023 12.4275 12.1887 9.11278 9.02639 10.4972 11.1692 11.3605 12.6167 14.3389 13.9289 13.9784 9.85502 8.68832 9.76037 9.90943 9.55161 10.8465 10.643 9.26625 0 0 9.20398 0 9.54944 12.2006 8.6576 P49458 SRP09_HUMAN Signal recognition particle 9 kDa protein (SRP9) SRP9 Homo sapiens (Human) negative regulation of translational elongation [GO:0045900]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614] "cytosol [GO:0005829]; signal recognition particle receptor complex [GO:0005785]; signal recognition particle, endoplasmic reticulum targeting [GO:0005786]" 7S RNA binding [GO:0008312]; RNA binding [GO:0003723]; signal recognition particle binding [GO:0005047] 0.89841 -0.66502 LYLADPMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.9145 0 0 0 0 0 0 0 8.63358 0 P49585 PCY1A_HUMAN Choline-phosphate cytidylyltransferase A (EC 2.7.7.15) (CCT-alpha) (CTP:phosphocholine cytidylyltransferase A) (CCT A) (CT A) (Phosphorylcholine transferase A) PCYT1A CTPCT PCYT1 Homo sapiens (Human) CDP-choline pathway [GO:0006657]; phosphatidylcholine biosynthetic process [GO:0006656] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glycogen granule [GO:0042587]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; plasma membrane [GO:0005886] calmodulin binding [GO:0005516]; choline-phosphate cytidylyltransferase activity [GO:0004105]; identical protein binding [GO:0042802]; molecular function inhibitor activity [GO:0140678]; phosphatidylcholine binding [GO:0031210]; protein homodimerization activity [GO:0042803] 0.85064 0.1659 EAGMFAPTQR 0 11.3598 0 0 0 9.55771 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P49588 SYAC_HUMAN "Alanine--tRNA ligase, cytoplasmic (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS) (Renal carcinoma antigen NY-REN-42)" AARS1 AARS Homo sapiens (Human) alanyl-tRNA aminoacylation [GO:0006419]; cerebellar Purkinje cell layer development [GO:0021680]; negative regulation of neuron apoptotic process [GO:0043524]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; regulation of cytoplasmic translational fidelity [GO:0140018]; tRNA aminoacylation for protein translation [GO:0006418]; tRNA modification [GO:0006400]; tRNA processing [GO:0008033] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739] alanine-tRNA ligase activity [GO:0004813]; amino acid binding [GO:0016597]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; Ser-tRNA(Ala) hydrolase activity [GO:0002196]; translation regulator activity [GO:0045182]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270] 0 4.5286 AVFDETYPDPVR 0 0 0 0 0 9.93497 9.35634 9.20391 0 10.8103 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P49591 SYSC_HUMAN "Serine--tRNA ligase, cytoplasmic (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)" SARS1 SARS SERS Homo sapiens (Human) cytoplasmic translation [GO:0002181]; negative regulation of angiogenesis [GO:0016525]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular endothelial growth factor production [GO:1904046]; selenocysteine incorporation [GO:0001514]; seryl-tRNA aminoacylation [GO:0006434]; translation [GO:0006412]; tRNA modification [GO:0006400] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634] ATP binding [GO:0005524]; enzyme binding [GO:0019899]; molecular adaptor activity [GO:0060090]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; selenocysteine-tRNA ligase activity [GO:0098619]; serine-tRNA ligase activity [GO:0004828]; tRNA binding [GO:0000049] 0.76289 0.29635 KQHEGSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1845 10.0058 0 0 0 0 0 0 0 0 0 0 P49641 MA2A2_HUMAN "Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)" MAN2A2 MANA2X Homo sapiens (Human) mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486] Golgi membrane [GO:0000139] "alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing N-glycosyl compounds [GO:0016799]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]" 0.46138 0.63657 GLGQGLK 0 0 0 0 0 0 0 15.4551 0 15.9173 0 0 0 0 0 0 0 0 0 0 0 0 11.0556 0 0 0 0 P49642 PRI1_HUMAN DNA primase small subunit (EC 2.7.7.102) (DNA primase 49 kDa subunit) (p49) PRIM1 Homo sapiens (Human) "DNA replication initiation [GO:0006270]; DNA replication, synthesis of RNA primer [GO:0006269]" alpha DNA polymerase:primase complex [GO:0005658]; membrane [GO:0016020]; nucleoplasm [GO:0005654] DNA primase activity [GO:0003896]; magnesium ion binding [GO:0000287]; ribonucleotide binding [GO:0032553]; zinc ion binding [GO:0008270] 0.95508 -1.5215 ALKEDFGFK 0 0 0 0 0 0 0 8.88353 0 0 0 0 0 0 8.81324 0 0 0 0 0 0 0 0 0 0 0 0 P49643 PRI2_HUMAN DNA primase large subunit (DNA primase 58 kDa subunit) (p58) PRIM2 PRIM2A Homo sapiens (Human) "DNA replication initiation [GO:0006270]; DNA replication, synthesis of RNA primer [GO:0006269]; positive regulation of DNA primase activity [GO:1903934]" alpha DNA polymerase:primase complex [GO:0005658]; nucleoplasm [GO:0005654] "4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; DNA/RNA hybrid binding [GO:0071667]; metal ion binding [GO:0046872]" 0.88393 -0.05352 MQYGLFLK 0 0 0 0 0 0 0 0 11.236 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P49662 CASP4_HUMAN Caspase-4 (CASP-4) (EC 3.4.22.57) (ICE and Ced-3 homolog 2) (ICH-2) (ICE(rel)-II) (Mih1) (Protease TX) [Cleaved into: Caspase-4 subunit p10; Caspase-4 subunit p20] CASP4 ICH2 Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to amyloid-beta [GO:1904646]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; non-canonical inflammasome complex assembly [GO:0160075]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-18-mediated signaling pathway [GO:2000494]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein autoprocessing [GO:0016540]; protein maturation [GO:0051604]; proteolysis [GO:0006508]; pyroptosis [GO:0070269]; regulation of apoptotic process [GO:0042981]; regulation of inflammatory response [GO:0050727] canonical inflammasome complex [GO:0061702]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; non-canonical inflammasome complex [GO:0160074]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] CARD domain binding [GO:0050700]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:0097200]; lipopolysaccharide binding [GO:0001530] 0.95473 -1.5203 AKAQMPTIER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5221 0 0 0 0 0 0 P49682 CXCR3_HUMAN C-X-C chemokine receptor type 3 (CXC-R3) (CXCR-3) (CKR-L2) (G protein-coupled receptor 9) (Interferon-inducible protein 10 receptor) (IP-10 receptor) (CD antigen CD183) CXCR3 GPR9 Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of execution phase of apoptosis [GO:1900118]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemotaxis [GO:0050921]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell adhesion [GO:0030155]; regulation of leukocyte migration [GO:0002685] cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; plasma membrane [GO:0005886] C-X-C chemokine binding [GO:0019958]; C-X-C chemokine receptor activity [GO:0016494]; chemokine binding [GO:0019956]; chemokine receptor activity [GO:0004950]; signaling receptor activity [GO:0038023] 0.88144 -0.30325 LGCPNQRGLQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.354 0 0 P49703 ARL4D_HUMAN ADP-ribosylation factor-like protein 4D (ADP-ribosylation factor-like protein 4L) ARL4D ARF4L Homo sapiens (Human) intracellular protein transport [GO:0006886]; protein secretion [GO:0009306]; vesicle-mediated transport [GO:0016192] cytoplasm [GO:0005737]; nucleolus [GO:0005730]; plasma membrane [GO:0005886] GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.90833 -0.74308 LYEMILKRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.487 0 11.1074 0 10.8571 0 0 0 0 0 0 0 0 P49715 CEBPA_HUMAN CCAAT/enhancer-binding protein alpha (C/EBP alpha) CEBPA CEBP Homo sapiens (Human) brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol metabolic process [GO:0008203]; cytokine-mediated signaling pathway [GO:0019221]; embryonic placenta development [GO:0001892]; epithelial cell maturation [GO:0002070]; fat cell differentiation [GO:0045444]; generation of precursor metabolites and energy [GO:0006091]; glucose homeostasis [GO:0042593]; granulocyte differentiation [GO:0030851]; hematopoietic stem cell proliferation [GO:0071425]; inner ear development [GO:0048839]; integrated stress response signaling [GO:0140467]; interleukin-6-mediated signaling pathway [GO:0070102]; lipid homeostasis [GO:0055088]; liver development [GO:0001889]; lung development [GO:0030324]; macrophage differentiation [GO:0030225]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hematopoietic stem cell proliferation [GO:1902034]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of DNA-templated transcription initiation [GO:2000144]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of macrophage activation [GO:0043032]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase I [GO:0006360]; urea cycle [GO:0000050]; white fat cell differentiation [GO:0050872] C/EBP complex [GO:1990647]; CHOP-C/EBP complex [GO:0036488]; chromatin [GO:0000785]; intracellular membrane-bounded organelle [GO:0043231]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575]; transcription regulator complex [GO:0005667] "chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; protein homodimerization activity [GO:0042803]; RNA polymerase I transcription regulatory region sequence-specific DNA binding [GO:0001163]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; STAT family protein binding [GO:0097677]; transcription cis-regulatory region binding [GO:0000976]" 0.91919 -0.89502 ASGGSGAGK 0 0 0 0 0 0 0 8.84229 0 0 8.67433 0 0 0 0 0 0 0 8.84141 0 0 0 0 0 0 0 0 P49716 CEBPD_HUMAN CCAAT/enhancer-binding protein delta (C/EBP delta) (Nuclear factor NF-IL6-beta) (NF-IL6-beta) CEBPD Homo sapiens (Human) fat cell differentiation [GO:0045444]; hematopoietic progenitor cell differentiation [GO:0002244]; inner ear development [GO:0048839]; integrated stress response signaling [GO:0140467]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell differentiation [GO:0045595]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.88301 -0.29973 NQEMQQK 0 0 0 0 0 0 10.3542 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P49736 MCM2_HUMAN DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28) MCM2 BM28 CCNL1 CDCL1 KIAA0030 Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to interleukin-4 [GO:0071353]; cochlea development [GO:0090102]; DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via break-induced replication [GO:0000727]; mitotic DNA replication initiation [GO:1902975]; negative regulation of DNA helicase activity [GO:1905775]; nucleosome assembly [GO:0006334]; regulation of DNA-templated DNA replication initiation [GO:0030174] "chromatin [GO:0000785]; chromosome, telomeric region [GO:0000781]; CMG complex [GO:0071162]; cytoplasm [GO:0005737]; MCM complex [GO:0042555]; nuclear origin of replication recognition complex [GO:0005664]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]" ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA binding [GO:0003677]; DNA replication origin binding [GO:0003688]; enzyme binding [GO:0019899]; helicase activity [GO:0004386]; histone binding [GO:0042393]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697] 0.95946 -1.84 ISDMCKENR 0 0 0 0 11.1083 0 0 0 0 0 0 0 0 0 0 11.9995 0 0 0 0 0 0 9.43983 0 0 0 0 P49747 COMP_HUMAN Cartilage oligomeric matrix protein (COMP) (Thrombospondin-5) (TSP5) COMP Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; artery morphogenesis [GO:0048844]; BMP signaling pathway [GO:0030509]; bone mineralization [GO:0030282]; cartilage homeostasis [GO:1990079]; chondrocyte development [GO:0002063]; chondrocyte proliferation [GO:0035988]; collagen fibril organization [GO:0030199]; growth plate cartilage development [GO:0003417]; limb development [GO:0060173]; multicellular organism aging [GO:0010259]; multicellular organism growth [GO:0035264]; musculoskeletal movement [GO:0050881]; negative regulation of apoptotic process [GO:0043066]; negative regulation of hemostasis [GO:1900047]; platelet aggregation [GO:0070527]; positive regulation of chondrocyte proliferation [GO:1902732]; protein homooligomerization [GO:0051260]; protein processing [GO:0016485]; protein secretion [GO:0009306]; regulation of bone mineralization [GO:0030500]; regulation of gene expression [GO:0010468]; response to unfolded protein [GO:0006986]; skeletal system development [GO:0001501]; skin development [GO:0043588]; tendon development [GO:0035989]; vascular associated smooth muscle cell development [GO:0097084]; vascular associated smooth muscle contraction [GO:0014829] extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991] BMP binding [GO:0036122]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; extracellular matrix structural constituent [GO:0005201]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; protease binding [GO:0002020]; proteoglycan binding [GO:0043394] 0.80796 0.22809 CINTSPGFR 9.35511 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P49748 ACADV_HUMAN "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (VLCAD) (EC 1.3.8.9)" ACADVL VLCAD Homo sapiens (Human) energy derivation by oxidation of organic compounds [GO:0015980]; epithelial cell differentiation [GO:0030855]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of fatty acid oxidation [GO:0046322]; regulation of cholesterol metabolic process [GO:0090181]; response to cold [GO:0009409]; temperature homeostasis [GO:0001659] mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] acyl-CoA dehydrogenase activity [GO:0003995]; fatty-acyl-CoA binding [GO:0000062]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; long-chain-acyl-CoA dehydrogenase activity [GO:0004466]; very-long-chain-acyl-CoA dehydrogenase activity [GO:0017099] 0 6.8001 ALEQFATVVEAK 9.6458 0 9.38079 0 0 0 9.30731 0 9.56894 0 0 0 0 8.43392 0 0 0 9.53382 0 0 0 0 0 0 0 10.271 9.97025 P49750 YLPM1_HUMAN YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113) YLPM1 C14orf170 ZAP3 Homo sapiens (Human) regulation of telomere maintenance [GO:0032204] cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] RNA binding [GO:0003723] 0.96945 -6.0219 DTPEPVK 0 11.2885 9.67377 0 0 0 0 9.00391 0 0 0 9.76663 0 0 0 0 0 0 0 0 0 0 0 0 8.81381 0 0 P49753 ACOT2_HUMAN "Acyl-coenzyme A thioesterase 2, mitochondrial (Acyl-CoA thioesterase 2) (EC 3.1.2.2) (Acyl-coenzyme A thioester hydrolase 2a) (CTE-Ia) (Long-chain acyl-CoA thioesterase 2) (ZAP128)" ACOT2 PTE2 PTE2A Homo sapiens (Human) acyl-CoA metabolic process [GO:0006637]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid metabolic process [GO:0001676]; very long-chain fatty acid metabolic process [GO:0000038] cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782] acyl-CoA hydrolase activity [GO:0047617]; carboxylic ester hydrolase activity [GO:0052689]; myristoyl-CoA hydrolase activity [GO:0102991]; palmitoyl-CoA hydrolase activity [GO:0016290] 0.94009 -1.3002 ASRLYQWSLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.14134 0 P49754 VPS41_HUMAN Vacuolar protein sorting-associated protein 41 homolog (S53) VPS41 Homo sapiens (Human) cellular response to starvation [GO:0009267]; endosomal vesicle fusion [GO:0034058]; endosome to lysosome transport [GO:0008333]; Golgi vesicle transport [GO:0048193]; late endosome to lysosome transport [GO:1902774]; macroautophagy [GO:0016236]; protein targeting to vacuole [GO:0006623]; regulation of SNARE complex assembly [GO:0035542]; vesicle-mediated transport [GO:0016192] clathrin-coated vesicle [GO:0030136]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle [GO:0005798]; HOPS complex [GO:0030897]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lysosomal HOPS complex [GO:1902501]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630] identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017] 0.9692 -3.894 DVVVAKER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0053 0 0 10.7817 0 0 P49756 RBM25_HUMAN RNA-binding protein 25 (Arg/Glu/Asp-rich protein of 120 kDa) (RED120) (Protein S164) (RNA-binding motif protein 25) (RNA-binding region-containing protein 7) RBM25 RNPC7 Homo sapiens (Human) "mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of apoptotic process [GO:0042981]; RNA splicing [GO:0008380]" cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654] mRNA binding [GO:0003729]; RNA binding [GO:0003723] 0.96895 -3.8916 ALRLLHDLQIGEKK 0 0 0 0 0 0 0 0 0 9.58939 0 0 0 0 0 10.5928 0 0 0 0 0 9.56276 0 0 0 0 0 P49757 NUMB_HUMAN Protein numb homolog (h-Numb) (Protein S171) NUMB C14orf41 Homo sapiens (Human) adherens junction organization [GO:0034332]; axonogenesis [GO:0007409]; lateral ventricle development [GO:0021670]; negative regulation of protein localization to plasma membrane [GO:1903077]; neuroblast division in subventricular zone [GO:0021849]; positive regulation of cell migration [GO:0030335]; positive regulation of neurogenesis [GO:0050769]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149] apical part of cell [GO:0045177]; basolateral plasma membrane [GO:0016323]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886] alpha-catenin binding [GO:0045294]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296] 0.91576 -0.76328 INELPSTMQRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4421 0 0 P49758 RGS6_HUMAN Regulator of G-protein signaling 6 (RGS6) (S914) RGS6 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886] GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924] 0.96702 -2.3227 DQVGRDQFLR 0 0 0 0 0 0 0 0 10.1165 0 0 0 10.1273 9.31204 9.0523 0 0 0 10.0741 0 0 0 10.941 0 0 0 0 P49759 CLK1_HUMAN Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1) CLK1 CLK Homo sapiens (Human) peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peptidyl-tyrosine phosphorylation [GO:0018108]; protein autophosphorylation [GO:0046777]; regulation of RNA splicing [GO:0043484] cytoplasm [GO:0005737]; nucleus [GO:0005634] ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein tyrosine kinase activity [GO:0004713] 0.96946 -4.0939 AGGRHVAVK 10.953 11.0449 0 0 0 0 0 0 0 11.9029 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P49760 CLK2_HUMAN Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2) CLK2 Homo sapiens (Human) negative regulation of gluconeogenesis [GO:0045721]; peptidyl-tyrosine phosphorylation [GO:0018108]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of RNA splicing [GO:0043484]; response to ionizing radiation [GO:0010212] nuclear body [GO:0016604]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; identical protein binding [GO:0042802]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein tyrosine kinase activity [GO:0004713] 0.88578 -0.33789 INEKDPDNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9811 0 0 0 0 0 0 0 0 0 0 0 0 P49761 CLK3_HUMAN Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3) CLK3 Homo sapiens (Human) peptidyl-tyrosine phosphorylation [GO:0018108]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of RNA splicing [GO:0043484] acrosomal vesicle [GO:0001669]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; identical protein binding [GO:0042802]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein tyrosine kinase activity [GO:0004713]; RNA binding [GO:0003723] 0.94001 -1.3257 EAARLEINVLKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.98917 0 0 0 0 0 0 0 0 0 0 P49767 VEGFC_HUMAN Vascular endothelial growth factor C (VEGF-C) (Flt4 ligand) (Flt4-L) (Vascular endothelial growth factor-related protein) (VRP) VEGFC Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cellular response to leukemia inhibitory factor [GO:1990830]; glial cell proliferation [GO:0014009]; induction of positive chemotaxis [GO:0050930]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of blood pressure [GO:0045776]; negative regulation of osteoblast differentiation [GO:0045668]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of lymphangiogenesis [GO:1901492]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal stem cell proliferation [GO:1902462]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein secretion [GO:0050714]; regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030947]; response to hypoxia [GO:0001666]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; substrate-dependent cell migration [GO:0006929]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084] extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093] chemoattractant activity [GO:0042056]; growth factor activity [GO:0008083]; vascular endothelial growth factor receptor 3 binding [GO:0043185] 0.91471 -0.81606 FHHQTCSCYR 0 0 0 0 0 0 0 0 0 0 9.82566 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P49770 EI2BB_HUMAN Translation initiation factor eIF-2B subunit beta (S20I15) (S20III15) (eIF-2B GDP-GTP exchange factor subunit beta) EIF2B2 EIF2BB Homo sapiens (Human) central nervous system development [GO:0007417]; myelination [GO:0042552]; oligodendrocyte development [GO:0014003]; ovarian follicle development [GO:0001541]; regulation of translational initiation [GO:0006446]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to peptide hormone [GO:0043434]; T cell receptor signaling pathway [GO:0050852]; translational initiation [GO:0006413] cytoplasm [GO:0005737]; cytosol [GO:0005829]; eukaryotic translation initiation factor 2B complex [GO:0005851] ATP binding [GO:0005524]; GTP binding [GO:0005525]; translation initiation factor activity [GO:0003743] 0.96247 -2.4971 IIREEYGR 0 0 0 0 0 0 0 0 9.91455 9.40476 0 0 0 0 0 0 0 0 10.9207 0 0 0 0 0 0 0 0 P49773 HINT1_HUMAN Adenosine 5'-monophosphoramidase HINT1 (EC 3.9.1.-) (Desumoylating isopeptidase HINT1) (EC 3.4.22.-) (Histidine triad nucleotide-binding protein 1) (Protein kinase C inhibitor 1) (Protein kinase C-interacting protein 1) (PKCI-1) HINT1 HINT PKCI1 PRKCNH1 Homo sapiens (Human) intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; protein desumoylation [GO:0016926]; purine ribonucleotide catabolic process [GO:0009154]; regulation of DNA-templated transcription [GO:0006355]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] adenosine 5'-monophosphoramidase activity [GO:0043530]; deSUMOylase activity [GO:0016929]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080] 0.88706 -0.34588 CAADLGLNKGYR 8.75599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P49788 TIG1_HUMAN Retinoic acid receptor responder protein 1 (Phorbol ester-induced gene 1 protein) (PERG-1) (RAR-responsive protein TIG1) (Tazarotene-induced gene 1 protein) RARRES1 PEIG1 TIG1 Homo sapiens (Human) negative regulation of cell population proliferation [GO:0008285] extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020] metalloendopeptidase inhibitor activity [GO:0008191] 0 7.603 LLQQAAR 0 8.75449 0 0 0 0 12.3822 12.2527 12.4032 9.06816 0 0 0 0 0 0 0 8.872 0 0 0 0 0 0 10.0463 10.3185 0 P49790 NU153_HUMAN Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153) NUP153 Homo sapiens (Human) mRNA transport [GO:0051028]; negative regulation of RNA export from nucleus [GO:0046832]; nuclear pore complex assembly [GO:0051292]; nucleocytoplasmic transport [GO:0006913]; protein import into nucleus [GO:0006606]; RNA export from nucleus [GO:0006405]; viral entry into host cell [GO:0046718]; viral penetration into host nucleus [GO:0075732] cytosol [GO:0005829]; host cell [GO:0043657]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear inclusion body [GO:0042405]; nuclear membrane [GO:0031965]; nuclear periphery [GO:0034399]; nuclear pore [GO:0005643]; nuclear pore nuclear basket [GO:0044615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] DNA binding [GO:0003677]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; nuclear localization sequence binding [GO:0008139]; protein-membrane adaptor activity [GO:0043495]; structural constituent of nuclear pore [GO:0017056] 0.95975 -1.9724 ILQSLEKMSSPLADAKR 0 0 0 0 0 0 0 0 0 9.60629 0 0 0 0 0 0 0 0 10.1813 0 0 0 0 0 0 0 0 P49792 RBP2_HUMAN E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) (p270) RANBP2 NUP358 Homo sapiens (Human) centrosome localization [GO:0051642]; mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; nuclear export [GO:0051168]; nucleocytoplasmic transport [GO:0006913]; positive regulation of glucokinase activity [GO:0033133]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein sumoylation [GO:0016925]; regulation of gluconeogenesis [GO:0006111] annulate lamellae [GO:0005642]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear inclusion body [GO:0042405]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear pore cytoplasmic filaments [GO:0044614]; nuclear pore nuclear basket [GO:0044615]; nucleoplasm [GO:0005654]; SUMO ligase complex [GO:0106068] metal ion binding [GO:0046872]; RNA binding [GO:0003723]; small GTPase binding [GO:0031267]; SUMO ligase activity [GO:0061665]; SUMO transferase activity [GO:0019789] 0.8841 -0.20478 DVGQWKER 0 0 0 0 0 0 0 0 0 0 0 0 10.2827 0 0 11.4742 0 0 0 10.1253 0 9.7749 0 0 0 10.2466 0 P49795 RGS19_HUMAN Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP) RGS19 GAIP GNAI3IP Homo sapiens (Human) autophagy [GO:0006914]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; response to ethanol [GO:0045471]; small GTPase mediated signal transduction [GO:0007264] brush border [GO:0005903]; clathrin-coated vesicle [GO:0030136]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886] G-protein alpha-subunit binding [GO:0001965]; GTPase activity [GO:0003924] 0.86123 0.098452 AEANQHVVDEKAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.53947 P49798 RGS4_HUMAN Regulator of G-protein signaling 4 (RGP4) (RGS4) RGS4 Homo sapiens (Human) brain development [GO:0007420]; dorsal root ganglion development [GO:1990791]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; negative regulation of dopamine receptor signaling pathway [GO:0060160]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of glycine import across plasma membrane [GO:1900924]; negative regulation of potassium ion transmembrane transport [GO:1901380]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of GTPase activity [GO:0043547]; positive regulation of heart rate [GO:0010460]; regulation of actin filament organization [GO:0110053]; regulation of calcium ion transport [GO:0051924]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to amphetamine [GO:0001975]; response to cocaine [GO:0042220]; response to ethanol [GO:0045471]; response to morphine [GO:0043278] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] calmodulin binding [GO:0005516]; G-protein alpha-subunit binding [GO:0001965]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; protein kinase binding [GO:0019901] 0.94751 -1.3479 IFNLMEKDSYR 0 11.7432 11.4261 11.3265 0 11.3432 0 11.7417 11.6573 0 10.5061 0 11.1755 11.4428 0 0 11.388 0 0 0 0 0 0 0 0 0 0 P49821 NDUV1_HUMAN "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (EC 7.1.1.2) (Complex I-51kD) (CI-51kD) (NADH dehydrogenase flavoprotein 1) (NADH-ubiquinone oxidoreductase 51 kDa subunit)" NDUFV1 UQOR1 Homo sapiens (Human) "aerobic respiration [GO:0009060]; mitochondrial ATP synthesis coupled electron transport [GO:0042775]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]" cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex I [GO:0005747]; mitochondrion [GO:0005739] "4 iron, 4 sulfur cluster binding [GO:0051539]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; NADH dehydrogenase (ubiquinone) activity [GO:0008137]" 0.91751 -0.87467 GDWYKTKEILLK 0 0 0 0 0 9.63303 0 0 0 0 0 0 0 0 0 0 0 0 10.1367 0 0 0 0 10.1167 0 0 0 P49840 GSK3A_HUMAN Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1) GSK3A Homo sapiens (Human) "aging [GO:0007568]; cardiac left ventricle morphogenesis [GO:0003214]; cell migration [GO:0016477]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-3 [GO:0036016]; cellular response to lithium ion [GO:0071285]; dopamine receptor signaling pathway [GO:0007212]; excitatory postsynaptic potential [GO:0060079]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; glycogen metabolic process [GO:0005977]; insulin receptor signaling pathway [GO:0008286]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; negative regulation of dendrite development [GO:2000171]; negative regulation of gene expression via CpG island methylation [GO:0044027]; negative regulation of glucose import [GO:0046325]; negative regulation of glycogen (starch) synthase activity [GO:2000466]; negative regulation of glycogen biosynthetic process [GO:0045719]; negative regulation of glycogen synthase activity, transferring glucose-1-phosphate [GO:1904227]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of TOR signaling [GO:0032007]; negative regulation of type B pancreatic cell development [GO:2000077]; negative regulation of UDP-glucose catabolic process [GO:0010905]; nervous system development [GO:0007399]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071879]; positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0106071]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of autophagy [GO:0010508]; positive regulation of gene expression [GO:0010628]; positive regulation of glycogen (starch) synthase activity [GO:2000467]; positive regulation of heart contraction [GO:0045823]; positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901030]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein phosphorylation [GO:0006468]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of gene expression by genomic imprinting [GO:0006349]; regulation of neuron projection development [GO:0010975]; regulation of systemic arterial blood pressure [GO:0003073]; viral protein processing [GO:0019082]; Wnt signaling pathway [GO:0016055]" apical dendrite [GO:0097440]; axon [GO:0030424]; beta-catenin destruction complex [GO:0030877]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; postsynapse [GO:0098794]; proximal dendrite [GO:1990635] ATP binding [GO:0005524]; protein kinase A catalytic subunit binding [GO:0034236]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine kinase binding [GO:0120283]; signaling receptor binding [GO:0005102]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321] 0.93885 -1.323 VARHFTK 0 0 0 0 0 0 0 0 0 8.90373 8.94351 8.74319 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P49841 GSK3B_HUMAN Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1) GSK3B Homo sapiens (Human) beta-catenin destruction complex disassembly [GO:1904886]; cellular response to amyloid-beta [GO:1904646]; cellular response to interleukin-3 [GO:0036016]; cellular response to retinoic acid [GO:0071300]; circadian rhythm [GO:0007623]; dopamine receptor signaling pathway [GO:0007212]; epithelial to mesenchymal transition [GO:0001837]; ER overload response [GO:0006983]; establishment of cell polarity [GO:0030010]; excitatory postsynaptic potential [GO:0060079]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; glycogen metabolic process [GO:0005977]; heart valve development [GO:0003170]; hippocampus development [GO:0021766]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; maintenance of cell polarity [GO:0030011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation [GO:1905240]; negative regulation of dopaminergic neuron differentiation [GO:1904339]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of gene expression [GO:0010629]; negative regulation of glycogen (starch) synthase activity [GO:2000466]; negative regulation of glycogen biosynthetic process [GO:0045719]; negative regulation of mesenchymal stem cell differentiation [GO:2000740]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of type B pancreatic cell development [GO:2000077]; neuron projection development [GO:0031175]; neuron projection organization [GO:0106027]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of autophagy [GO:0010508]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cilium assembly [GO:0045724]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901030]; positive regulation of mitochondrion organization [GO:0010822]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein localization to centrosome [GO:1904781]; positive regulation of protein localization to cilium [GO:1903566]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of protein-containing complex assembly [GO:0031334]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axon extension [GO:0030516]; regulation of axonogenesis [GO:0050770]; regulation of cellular response to heat [GO:1900034]; regulation of circadian rhythm [GO:0042752]; regulation of dendrite morphogenesis [GO:0048814]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of microtubule anchoring at centrosome [GO:0150101]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of microtubule-based process [GO:0032886]; regulation of neuron projection development [GO:0010975]; regulation of protein export from nucleus [GO:0046825]; superior temporal gyrus development [GO:0071109]; viral protein processing [GO:0019082] axon [GO:0030424]; beta-catenin destruction complex [GO:0030877]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; presynapse [GO:0098793]; Wnt signalosome [GO:1990909] ATP binding [GO:0005524]; beta-catenin binding [GO:0008013]; dynactin binding [GO:0034452]; kinase activity [GO:0016301]; NF-kappaB binding [GO:0051059]; p53 binding [GO:0002039]; protease binding [GO:0002020]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321]; ubiquitin protein ligase binding [GO:0031625] 0.84838 0.1724 LYMYQLFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1381 P49842 STK19_HUMAN Serine/threonine-protein kinase 19 (EC 2.7.11.1) (Protein G11) (Protein RP1) STK19 G11 RP1 Homo sapiens (Human) positive regulation of Ras protein signal transduction [GO:0046579]; protein phosphorylation [GO:0006468] nuclear speck [GO:0016607]; nucleus [GO:0005634] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; small GTPase binding [GO:0031267] 0.89868 -0.66653 ELLLSELLGRR 0 0 0 0 0 0 12.0075 0 12.6347 0 11.1201 10.8786 0 0 10.1793 0 0 0 0 0 9.60529 0 0 0 0 9.88733 9.60578 P49848 TAF6_HUMAN Transcription initiation factor TFIID subunit 6 (RNA polymerase II TBP-associated factor subunit E) (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII70) (Transcription initiation factor TFIID 80 kDa subunit) (TAF(II)80) (TAFII-80) (TAFII80) TAF6 TAF2E TAFII70 Homo sapiens (Human) apoptotic process [GO:0006915]; DNA-templated transcription initiation [GO:0006352]; histone H3 acetylation [GO:0043966]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transcription initiation at RNA polymerase II promoter [GO:0006367] cytosol [GO:0005829]; MLL1 complex [GO:0071339]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; SAGA complex [GO:0000124]; SLIK (SAGA-like) complex [GO:0046695]; transcription factor TFIID complex [GO:0005669]; transcription factor TFTC complex [GO:0033276] aryl hydrocarbon receptor binding [GO:0017162]; DNA binding [GO:0003677]; molecular adaptor activity [GO:0060090]; protein heterodimerization activity [GO:0046982]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; transcription coactivator activity [GO:0003713] 0.8292 0.20528 EITEACVGSCEAK 0 0 0 0 0 0 0 0 0 0 0 8.80964 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P49910 ZN165_HUMAN Zinc finger protein 165 (Cancer/testis antigen 53) (CT53) (LD65) (Zinc finger and SCAN domain-containing protein 7) ZNF165 ZPF165 ZSCAN7 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96684 -2.3528 EKPYECSECGK 10.7659 10.8711 10.7897 9.91174 9.27452 10.0293 10.9543 10.9609 10.9593 10.9125 11.0108 10.8162 10.4424 8.97585 9.05061 9.76747 10.6747 11.0851 0 0 0 0 0 0 0 0 0 P49915 GUAA_HUMAN GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) (GMP synthetase) (Glutamine amidotransferase) GMPS Homo sapiens (Human) glutamine metabolic process [GO:0006541]; GMP biosynthetic process [GO:0006177]; purine nucleobase biosynthetic process [GO:0009113]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168] cytosol [GO:0005829] ATP binding [GO:0005524]; GMP synthase (glutamine-hydrolyzing) activity [GO:0003922]; GMP synthase activity [GO:0003921] 0.95935 -1.7516 ELECIREIK 0 0 0 0 0 0 0 0 0 0 11.8308 0 0 0 9.22345 0 0 0 0 0 0 0 0 0 0 0 0 P49916 DNLI3_HUMAN DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3) LIG3 Homo sapiens (Human) "base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation [GO:0006266]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; lagging strand elongation [GO:0006273]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of mitochondrial DNA replication [GO:0090298]" DNA ligase III-XRCC1 complex [GO:0070421]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA ligase (ATP) activity [GO:0003910]; DNA ligase activity [GO:0003909]; zinc ion binding [GO:0008270] 0.89902 -0.64214 AAGTPKK 8.68113 15.6249 8.42105 0 0 0 0 0 0 0 9.70058 0 0 0 0 10.5431 0 0 0 9.7491 0 0 0 10.388 0 0 8.904 P49917 DNLI4_HUMAN DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4) LIG4 Homo sapiens (Human) "cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; cellular response to ionizing radiation [GO:0071479]; cellular response to lithium ion [GO:0071285]; central nervous system development [GO:0007417]; chromosome organization [GO:0051276]; DN2 thymocyte differentiation [GO:1904155]; DNA biosynthetic process [GO:0071897]; DNA ligation [GO:0006266]; DNA ligation involved in DNA recombination [GO:0051102]; DNA ligation involved in DNA repair [GO:0051103]; DNA replication [GO:0006260]; double-strand break repair [GO:0006302]; double-strand break repair via classical nonhomologous end joining [GO:0097680]; double-strand break repair via nonhomologous end joining [GO:0006303]; establishment of integrated proviral latency [GO:0075713]; fibroblast proliferation [GO:0048144]; immunoglobulin V(D)J recombination [GO:0033152]; in utero embryonic development [GO:0001701]; isotype switching [GO:0045190]; negative regulation of neuron apoptotic process [GO:0043524]; neurogenesis [GO:0022008]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair, DNA gap filling [GO:0006297]; positive regulation of chromosome organization [GO:2001252]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of neurogenesis [GO:0050769]; pro-B cell differentiation [GO:0002328]; response to gamma radiation [GO:0010332]; response to X-ray [GO:0010165]; single strand break repair [GO:0000012]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; T cell differentiation in thymus [GO:0033077]; T cell receptor V(D)J recombination [GO:0033153]; V(D)J recombination [GO:0033151]" "chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cytoplasmic ribonucleoprotein granule [GO:0036464]; DNA ligase IV complex [GO:0032807]; DNA-dependent protein kinase-DNA ligase 4 complex [GO:0005958]; nonhomologous end joining complex [GO:0070419]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]" ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA ligase (ATP) activity [GO:0003910]; DNA ligase activity [GO:0003909]; ligase activity [GO:0016874]; metal ion binding [GO:0046872] 0.95909 -1.9526 DGDVYKYFSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.5745 0 0 0 P49959 MRE11_HUMAN Double-strand break repair protein MRE11 (EC 3.1.-.-) (Double-strand break repair protein MRE11A) (Meiotic recombination 11 homolog 1) (MRE11 homolog 1) (Meiotic recombination 11 homolog A) (MRE11 homolog A) MRE11 HNGS1 MRE11A Homo sapiens (Human) cell population proliferation [GO:0008283]; DNA damage response [GO:0006974]; DNA double-strand break processing [GO:0000729]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA strand resection involved in replication fork processing [GO:0110025]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; homologous chromosome pairing at meiosis [GO:0007129]; homologous recombination [GO:0035825]; meiotic DNA double-strand break formation [GO:0042138]; mitochondrial double-strand break repair via homologous recombination [GO:0097552]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; mitotic G2/M transition checkpoint [GO:0044818]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; negative regulation of apoptotic process [GO:0043066]; positive regulation of kinase activity [GO:0033674]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of telomere maintenance [GO:0032206]; reciprocal meiotic recombination [GO:0007131]; regulation of mitotic recombination [GO:0000019]; sister chromatid cohesion [GO:0007062]; telomere maintenance [GO:0000723]; telomere maintenance via telomerase [GO:0007004]; telomeric 3' overhang formation [GO:0031860] "BRCA1-C complex [GO:0070533]; chromosomal region [GO:0098687]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Mre11 complex [GO:0030870]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]" 3'-5' exonuclease activity [GO:0008408]; 3'-5'-DNA exonuclease activity [GO:0008296]; 5'-3' exonuclease activity [GO:0008409]; cadherin binding [GO:0045296]; DNA endonuclease activity [GO:0004520]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; nuclease activity [GO:0004518]; single-stranded DNA endodeoxyribonuclease activity [GO:0000014] 0.95177 -1.3838 QYFQTAEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0108 0 P49961 ENTP1_HUMAN Ectonucleoside triphosphate diphosphohydrolase 1 (NTPDase 1) (EC 3.6.1.5) (Ecto-ATP diphosphohydrolase 1) (Ecto-ATPDase 1) (Ecto-ATPase 1) (Ecto-apyrase) (Lymphoid cell activation antigen) (CD antigen CD39) ENTPD1 CD39 Homo sapiens (Human) blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; nucleoside diphosphate catabolic process [GO:0009134] extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; GDP phosphatase activity [GO:0004382]; UDP phosphatase activity [GO:0045134] 0.72971 0.33393 DYNVYTHSFLCYGK 0 0 0 0 0 0 0 9.40882 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P50148 GNAQ_HUMAN Guanine nucleotide-binding protein G(q) subunit alpha (Guanine nucleotide-binding protein alpha-q) GNAQ GAQ Homo sapiens (Human) "action potential [GO:0001508]; activation of phospholipase C activity [GO:0007202]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; blood coagulation [GO:0007596]; entrainment of circadian clock [GO:0009649]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; glutamate receptor signaling pathway [GO:0007215]; negative regulation of protein kinase activity [GO:0006469]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; phototransduction, visible light [GO:0007603]; protein stabilization [GO:0050821]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of platelet activation [GO:0010543]" cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; heterotrimeric G-protein complex [GO:0005834]; lysosomal membrane [GO:0005765]; nuclear membrane [GO:0031965]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; synapse [GO:0045202] G protein-coupled receptor binding [GO:0001664]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GTP binding [GO:0005525]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872] 0.8509 0.16168 ELKLLLLGTGESGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.73305 0 0 0 0 0 0 P50219 MNX1_HUMAN Motor neuron and pancreas homeobox protein 1 (Homeobox protein HB9) MNX1 HLXB9 Homo sapiens (Human) central nervous system development [GO:0007417]; endocrine pancreas development [GO:0031018]; neuron projection morphogenesis [GO:0048812]; spinal cord motor neuron cell fate specification [GO:0021520] chromatin [GO:0000785]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.918 -0.85615 GGGGGAGK 0 0 0 0 0 7.88905 0 0 0 8.98707 0 9.31352 0 0 0 0 0 0 10.046 9.24805 0 0 0 0 0 0 0 P50395 GDIB_HUMAN Rab GDP dissociation inhibitor beta (Rab GDI beta) (Guanosine diphosphate dissociation inhibitor 2) (GDI-2) GDI2 RABGDIB Homo sapiens (Human) negative regulation of cilium assembly [GO:1902018]; negative regulation of protein localization to cilium [GO:1903565]; protein transport [GO:0015031]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192] azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; secretory granule lumen [GO:0034774]; synapse [GO:0045202]; vesicle [GO:0031982] GTPase activator activity [GO:0005096]; Rab GDP-dissociation inhibitor activity [GO:0005093]; RNA binding [GO:0003723]; small GTPase binding [GO:0031267] 0 32.663 DLGTESQIFISR 0 0 0 0 0 0 8.91889 0 9.78328 10.4509 10.406 9.19876 11.0153 11.828 9.39124 9.03262 9.09199 0 10.6495 10.4896 11.0415 10.3584 9.68697 10.6635 10.6966 9.6935 12.2414 P50416 CPT1A_HUMAN "Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A)" CPT1A CPT1 Homo sapiens (Human) carnitine metabolic process [GO:0009437]; carnitine shuttle [GO:0006853]; cellular response to fatty acid [GO:0071398]; eating behavior [GO:0042755]; epithelial cell differentiation [GO:0030855]; fatty acid beta-oxidation [GO:0006635]; fatty acid metabolic process [GO:0006631]; glucose metabolic process [GO:0006006]; liver regeneration [GO:0097421]; long-chain fatty acid metabolic process [GO:0001676]; positive regulation of fatty acid beta-oxidation [GO:0032000]; regulation of insulin secretion [GO:0050796]; regulation of lipid storage [GO:0010883]; response to alkaloid [GO:0043279]; response to antibiotic [GO:0046677]; response to ethanol [GO:0045471]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to tetrachloromethane [GO:1904772]; response to xenobiotic stimulus [GO:0009410]; triglyceride metabolic process [GO:0006641] membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739] carnitine O-palmitoyltransferase activity [GO:0004095]; identical protein binding [GO:0042802]; palmitoleoyltransferase activity [GO:1990698] 0.89627 -0.54186 AMVDPAQTVEQRLK 0 0 0 0 0 0 0 0 0 0 0 0 13.3108 0 0 0 0 0 0 0 0 9.74631 9.90466 0 0 0 0 P50440 GATM_HUMAN "Glycine amidinotransferase, mitochondrial (EC 2.1.4.1) (L-arginine:glycine amidinotransferase) (Transamidinase)" GATM AGAT Homo sapiens (Human) creatine biosynthetic process [GO:0006601]; creatine metabolic process [GO:0006600]; learning or memory [GO:0007611]; muscle atrophy [GO:0014889]; positive regulation of cold-induced thermogenesis [GO:0120162] extracellular exosome [GO:0070062]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739] amidinotransferase activity [GO:0015067]; glycine amidinotransferase activity [GO:0015068] 0.91611 -0.83968 KAVAEIEEMCNILK 10.0647 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P50453 SPB9_HUMAN Serpin B9 (Cytoplasmic antiproteinase 3) (CAP-3) (CAP3) (Peptidase inhibitor 9) (PI-9) SERPINB9 PI9 Homo sapiens (Human) cellular response to estrogen stimulus [GO:0071391]; immune response [GO:0006955]; mast cell mediated immunity [GO:0002448]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endopeptidase activity [GO:0010951]; protection from natural killer cell mediated cytotoxicity [GO:0042270] collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; protease binding [GO:0002020]; serine-type endopeptidase inhibitor activity [GO:0004867] 0.91558 -0.76393 HLGIVDAFQQGK 0 9.78789 9.87498 0 0 0 0 0 0 9.02948 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P50454 SERPH_HUMAN Serpin H1 (47 kDa heat shock protein) (Arsenic-transactivated protein 3) (AsTP3) (Cell proliferation-inducing gene 14 protein) (Collagen-binding protein) (Colligin) (Rheumatoid arthritis-related antigen RA-A47) SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 Homo sapiens (Human) chondrocyte development involved in endochondral bone morphogenesis [GO:0003433]; collagen biosynthetic process [GO:0032964]; collagen fibril organization [GO:0030199]; negative regulation of endopeptidase activity [GO:0010951]; protein maturation [GO:0051604]; response to unfolded protein [GO:0006986] collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular space [GO:0005615]; membrane raft [GO:0045121] collagen binding [GO:0005518]; RNA binding [GO:0003723]; serine-type endopeptidase inhibitor activity [GO:0004867]; unfolded protein binding [GO:0051082] 0 8.9209 DTQSGSLLFIGR 0 0 0 0 0 0 10.7304 0 0 0 0 0 0 0 0 0 0 11.7539 10.2423 9.2479 9.25899 8.9978 8.93236 8.90433 0 0 10.0188 P50502 F10A1_HUMAN Hsc70-interacting protein (Hip) (Aging-associated protein 2) (Progesterone receptor-associated p48 protein) (Protein FAM10A1) (Putative tumor suppressor ST13) (Renal carcinoma antigen NY-REN-33) (Suppression of tumorigenicity 13 protein) ST13 AAG2 FAM10A1 HIP SNC6 Homo sapiens (Human) chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to bacterium [GO:0009617] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062] Hsp70 protein binding [GO:0030544]; protein dimerization activity [GO:0046983]; protein-macromolecule adaptor activity [GO:0030674] 0.006192 2.6837 AIDLFTDAIK 0 0 0 0 0 0 9.83314 8.93245 8.88594 10.31 10.7328 8.90165 9.29783 0 0 9.39348 10.9969 9.78727 0 0 0 0 0 0 9.59606 0 0 P50539 MXI1_HUMAN Max-interacting protein 1 (Max interactor 1) (Class C basic helix-loop-helix protein 11) (bHLHc11) MXI1 BHLHC11 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein dimerization activity [GO:0046983]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.92368 -1.0363 EQRFLKWR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.79969 0 0 0 0 0 0 0 0 P50548 ERF_HUMAN ETS domain-containing transcription factor ERF (Ets2 repressor factor) (PE-2) ERF Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; sequence-specific DNA binding [GO:0043565]" 0.93897 -1.2965 KVRGEGPGEAGGPLTPR 0 12.4165 12.5419 0 0 0 0 0 0 0 0 12.6957 11.0183 0 0 0 0 11.4772 0 0 0 0 0 0 0 0 0 P50549 ETV1_HUMAN ETS translocation variant 1 (Ets-related protein 81) ETV1 ER81 Homo sapiens (Human) axon guidance [GO:0007411]; mechanosensory behavior [GO:0007638]; muscle organ development [GO:0007517]; peripheral nervous system neuron development [GO:0048935]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.92034 -0.92677 EPHSPCSEISSACSQEQPFK 0 0 0 0 0 9.00714 0 0 0 0 0 0 0 0 0 0 0 10.3476 0 0 0 0 0 0 0 0 0 P50570 DYN2_HUMAN Dynamin-2 (EC 3.6.5.5) DNM2 DYN2 Homo sapiens (Human) antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to carbon monoxide [GO:0071245]; cellular response to dopamine [GO:1903351]; cellular response to nitric oxide [GO:0071732]; cellular response to X-ray [GO:0071481]; endocytosis [GO:0006897]; G protein-coupled receptor internalization [GO:0002031]; G2/M transition of mitotic cell cycle [GO:0000086]; Golgi to plasma membrane transport [GO:0006893]; macropinocytosis [GO:0044351]; membrane organization [GO:0061024]; negative regulation of membrane tubulation [GO:1903526]; negative regulation of non-motile cilium assembly [GO:1902856]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; phagocytosis [GO:0006909]; positive regulation of apoptotic process [GO:0043065]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of P-type sodium:potassium-exchanging transporter activity [GO:1903408]; positive regulation of phagocytosis [GO:0050766]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; post-Golgi vesicle-mediated transport [GO:0006892]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of axon extension [GO:0030516]; regulation of DNA-templated transcription [GO:0006355]; regulation of Golgi organization [GO:1903358]; regulation of Rac protein signal transduction [GO:0035020]; response to cocaine [GO:0042220]; response to light stimulus [GO:0009416]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle transport [GO:0048489]; transferrin transport [GO:0033572] "centrosome [GO:0005813]; clathrin-coated endocytic vesicle [GO:0045334]; clathrin-coated pit [GO:0005905]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; membrane [GO:0016020]; microtubule [GO:0005874]; midbody [GO:0030496]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; phagocytic cup [GO:0001891]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic membrane [GO:0045211]; presynapse [GO:0098793]; protein-containing complex [GO:0032991]; ruffle membrane [GO:0032587]; trans-Golgi network [GO:0005802]" D2 dopamine receptor binding [GO:0031749]; enzyme binding [GO:0019899]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; microtubule binding [GO:0008017]; nitric-oxide synthase binding [GO:0050998]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein serine/threonine kinase binding [GO:0120283]; protein-containing complex binding [GO:0044877]; SH3 domain binding [GO:0017124]; WW domain binding [GO:0050699] 0.21212 0.90571 AALAAER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0243 0 9.70536 0 13.9917 0 0 0 0 0 0 P50748 KNTC1_HUMAN Kinetochore-associated protein 1 (Rough deal homolog) (HsROD) (Rod) (hRod) KNTC1 KIAA0166 Homo sapiens (Human) cell division [GO:0051301]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint signaling [GO:0007094]; protein localization to kinetochore involved in kinetochore assembly [GO:1903394]; protein-containing complex assembly [GO:0065003]; regulation of exit from mitosis [GO:0007096] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore microtubule [GO:0005828]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; RZZ complex [GO:1990423]; spindle pole [GO:0000922] small GTPase binding [GO:0031267] 0.91093 -0.74849 DVFENLWK 0 0 0 0 0 0 0 0 0 0 0 10.7027 0 9.18421 0 0 0 0 9.77926 0 0 9.42438 0 0 0 0 0 P50750 CDK9_HUMAN Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit) CDK9 CDC2L4 TAK Homo sapiens (Human) cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of protein localization to chromatin [GO:0120186]; nucleus localization [GO:0051647]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of protein localization to chromatin [GO:0120187]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of DNA repair [GO:0006282]; regulation of mRNA 3'-end processing [GO:0031440]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to xenobiotic stimulus [GO:0009410]; transcription by RNA polymerase II [GO:0006366]; transcription elongation by RNA polymerase II [GO:0006368]; transcription elongation-coupled chromatin remodeling [GO:0140673]; transcription initiation at RNA polymerase II promoter [GO:0006367] cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-TEFb complex [GO:0070691]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023] 7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; molecular function activator activity [GO:0140677]; molecular function inhibitor activity [GO:0140678]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; transcription coactivator binding [GO:0001223] 0.96338 -2.1212 LADFGLARAFSLAK 10.9524 0 11.0025 9.88877 10.5408 10.1157 0 0 0 10.6557 10.7496 0 0 0 10.5558 10.8741 11.1518 0 0 0 0 0 0 0 0 0 0 P50851 LRBA_HUMAN Lipopolysaccharide-responsive and beige-like anchor protein (Beige-like protein) (CDC4-like protein) LRBA BGL CDC4L LBA Homo sapiens (Human) mitophagy [GO:0000423]; protein localization [GO:0008104]; protein localization to phagophore assembly site [GO:0034497] cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886] protein kinase binding [GO:0019901] 0.88973 -0.47165 DINVSVGSQQPDTK 0 9.90823 10.0251 0 0 0 9.14542 0 0 10.969 11.7784 11.6304 11.2825 0 0 10.9812 0 0 0 0 0 0 0 0 0 9.2988 9.6705 P50895 BCAM_HUMAN Basal cell adhesion molecule (Auberger B antigen) (B-CAM cell surface glycoprotein) (F8/G253 antigen) (Lutheran antigen) (Lutheran blood group glycoprotein) (CD antigen CD239) BCAM LU MSK19 Homo sapiens (Human) cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; signal transduction [GO:0007165] collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; plasma membrane [GO:0005886] laminin binding [GO:0043236]; laminin receptor activity [GO:0005055]; transmembrane signaling receptor activity [GO:0004888] 0.006135 2.6241 GQSGTYGCR 0 9.70276 0 0 0 0 10.0291 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.8986 0 0 P50897 PPT1_HUMAN Palmitoyl-protein thioesterase 1 (PPT-1) (EC 3.1.2.22) (Palmitoyl-protein hydrolase 1) PPT1 CLN1 PPT Homo sapiens (Human) adult locomotory behavior [GO:0008344]; associative learning [GO:0008306]; brain development [GO:0007420]; fatty-acyl-CoA biosynthetic process [GO:0046949]; grooming behavior [GO:0007625]; lipid catabolic process [GO:0016042]; lysosomal lumen acidification [GO:0007042]; membrane raft organization [GO:0031579]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; neuron development [GO:0048666]; neurotransmitter secretion [GO:0007269]; pinocytosis [GO:0006907]; positive regulation of pinocytosis [GO:0048549]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein catabolic process [GO:0030163]; protein depalmitoylation [GO:0002084]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; regulation of phospholipase A2 activity [GO:0032429]; regulation of synapse structure or activity [GO:0050803]; response to stimulus [GO:0050896]; sphingolipid catabolic process [GO:0030149]; visual perception [GO:0007601] axon [GO:0030424]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; synaptic vesicle [GO:0008021] lysophosphatidic acid binding [GO:0035727]; palmitoyl-(protein) hydrolase activity [GO:0008474]; palmitoyl-CoA hydrolase activity [GO:0016290]; sulfatide binding [GO:0120146] 0.48718 0.62105 KTLNAGAYSK 0 0 0 0 0 0 0 0 0 0 0 0 9.55662 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P50914 RL14_HUMAN Large ribosomal subunit protein eL14 (60S ribosomal protein L14) (CAG-ISL 7) RPL14 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; ribosomal large subunit biogenesis [GO:0042273]; rRNA processing [GO:0006364]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; postsynaptic density [GO:0014069] cadherin binding [GO:0045296]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.925 -0.97754 ALVDGPCTQVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0511 0 10.1111 0 P50990 TCPQ_HUMAN T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) (Chaperonin containing T-complex polypeptide 1 subunit 8) (Renal carcinoma antigen NY-REN-15) CCT8 C21orf112 CCTQ KIAA0002 Homo sapiens (Human) binding of sperm to zona pellucida [GO:0007339]; chaperone-mediated protein folding [GO:0061077]; pore complex assembly [GO:0046931]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of protein localization to Cajal body [GO:1904871]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; toxin transport [GO:1901998] azurophil granule lumen [GO:0035578]; cell body [GO:0044297]; centrosome [GO:0005813]; chaperonin-containing T-complex [GO:0005832]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament cytoskeleton [GO:0045111]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; secretory granule lumen [GO:0034774]; zona pellucida receptor complex [GO:0002199] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; cadherin binding [GO:0045296]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082] 0 10.719 AIADTGANVVVTGGK 9.66601 9.71534 9.48758 0 0 0 10.8752 11.0905 10.7012 10.1215 10.066 10.6324 0 8.49474 0 11.1124 11.5538 9.91968 10.4339 0 0 10.7955 10.4756 0 10.4899 10.2855 11.7345 P50991 TCPD_HUMAN T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (Stimulator of TAR RNA-binding) CCT4 CCTD SRB Homo sapiens (Human) binding of sperm to zona pellucida [GO:0007339]; chaperone-mediated protein folding [GO:0061077]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of protein localization to Cajal body [GO:1904871]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; scaRNA localization to Cajal body [GO:0090666]; toxin transport [GO:1901998] cell body [GO:0044297]; cell projection [GO:0042995]; centrosome [GO:0005813]; chaperonin-containing T-complex [GO:0005832]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; melanosome [GO:0042470]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; zona pellucida receptor complex [GO:0002199] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082] 0 4.0425 ALIAGGGAPEIELALR 0 0 0 0 0 0 9.65258 0 0 10.4891 0 0 0 9.62839 0 9.54566 0 0 9.6658 0 0 0 0 0 0 0 0 P50993 AT1A2_HUMAN Sodium/potassium-transporting ATPase subunit alpha-2 (Na(+)/K(+) ATPase alpha-2 subunit) (EC 7.2.2.13) (Sodium pump subunit alpha-2) ATP1A2 KIAA0778 Homo sapiens (Human) "adult locomotory behavior [GO:0008344]; amygdala development [GO:0021764]; ATP metabolic process [GO:0046034]; behavioral fear response [GO:0001662]; cardiac muscle contraction [GO:0060048]; cell communication by electrical coupling involved in cardiac conduction [GO:0086064]; cellular response to mechanical stimulus [GO:0071260]; cellular response to steroid hormone stimulus [GO:0071383]; intracellular potassium ion homeostasis [GO:0030007]; intracellular sodium ion homeostasis [GO:0006883]; locomotion [GO:0040011]; locomotory exploration behavior [GO:0035641]; membrane depolarization during cardiac muscle cell action potential [GO:0086012]; membrane repolarization [GO:0086009]; monoatomic cation transmembrane transport [GO:0098655]; negative regulation of calcium ion transmembrane transport [GO:1903170]; negative regulation of calcium:sodium antiporter activity [GO:1903280]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of heart contraction [GO:0045822]; negative regulation of striated muscle contraction [GO:0045988]; neurotransmitter uptake [GO:0001504]; olfactory cortex development [GO:0021989]; positive regulation of heart contraction [GO:0045823]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; proton transmembrane transport [GO:1902600]; regulation of blood pressure [GO:0008217]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of glutamate uptake involved in transmission of nerve impulse [GO:0051946]; regulation of muscle contraction [GO:0006937]; regulation of respiratory gaseous exchange by nervous system process [GO:0002087]; regulation of smooth muscle contraction [GO:0006940]; regulation of striated muscle contraction [GO:0006942]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of the force of heart contraction [GO:0002026]; regulation of vasoconstriction [GO:0019229]; relaxation of cardiac muscle [GO:0055119]; response to auditory stimulus [GO:0010996]; response to glycoside [GO:1903416]; response to nicotine [GO:0035094]; sodium ion export across plasma membrane [GO:0036376]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]; transport across blood-brain barrier [GO:0150104]; visual learning [GO:0008542]" caveola [GO:0005901]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; endosome [GO:0005768]; extracellular vesicle [GO:1903561]; intercalated disc [GO:0014704]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; organelle membrane [GO:0031090]; plasma membrane [GO:0005886]; sodium:potassium-exchanging ATPase complex [GO:0005890]; T-tubule [GO:0030315] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled monoatomic cation transmembrane transporter activity [GO:0019829]; P-type sodium:potassium-exchanging transporter activity [GO:0005391]; phosphatase activity [GO:0016791]; potassium ion binding [GO:0030955]; protein heterodimerization activity [GO:0046982]; protein-folding chaperone binding [GO:0051087]; sodium ion binding [GO:0031402]; steroid binding [GO:0005496]; steroid hormone binding [GO:1990239] 0.92424 -0.95273 EVAMDDHKLSLDELGRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.97284 0 P50995 ANX11_HUMAN Annexin A11 (56 kDa autoantigen) (Annexin XI) (Annexin-11) (Calcyclin-associated annexin 50) (CAP-50) ANXA11 ANX11 Homo sapiens (Human) cytokinetic process [GO:0032506]; phagocytosis [GO:0006909]; response to calcium ion [GO:0051592] azurophil granule [GO:0042582]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; phagocytic vesicle [GO:0045335]; specific granule [GO:0042581]; spindle [GO:0005819] calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; MHC class II protein complex binding [GO:0023026]; phosphatidylethanolamine binding [GO:0008429]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548] 0.96951 -4.8945 ILLKICGGND 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.908 9.21199 0 P51114 FXR1_HUMAN RNA-binding protein FXR1 (FMR1 autosomal homolog 1) (hFXR1p) FXR1 Homo sapiens (Human) "apoptotic process [GO:0006915]; dentate gyrus development [GO:0021542]; mRNA destabilization [GO:0061157]; muscle organ development [GO:0007517]; negative regulation of inflammatory response [GO:0050728]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of translation [GO:0017148]; negative regulation of tumor necrosis factor production [GO:0032720]; non-membrane-bounded organelle assembly [GO:0140694]; nuclear pore complex assembly [GO:0051292]; nuclear pore localization [GO:0051664]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of filopodium assembly [GO:0051489]; regulation of mRNA stability [GO:0043488]; regulation of neurogenesis [GO:0050767]; regulation of synaptic transmission, glutamatergic [GO:0051966]; skeletal muscle organ development [GO:0060538]; spermatid development [GO:0007286]" axon [GO:0030424]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; dendritic filopodium [GO:1902737]; dendritic spine [GO:0043197]; dendritic spine neck [GO:0044326]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; intracellular non-membrane-bounded organelle [GO:0043232]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; polysome [GO:0005844]; postsynaptic density [GO:0014069]; presynapse [GO:0098793] molecular condensate scaffold activity [GO:0140693]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA strand annealing activity [GO:0033592]; translation regulator activity [GO:0045182] 0.95457 -1.5194 LQIDEQLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0318 0 0 0 0 0 0 0 0 0 0 P51116 FXR2_HUMAN RNA-binding protein FXR2 (FXR2P) (FMR1 autosomal homolog 2) FXR2 FMR1L2 Homo sapiens (Human) "dentate gyrus development [GO:0021542]; mRNA destabilization [GO:0061157]; negative regulation of translation [GO:0017148]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of filopodium assembly [GO:0051489]; regulation of mRNA stability [GO:0043488]" axon [GO:0030424]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; dendritic filopodium [GO:1902737]; dendritic spine [GO:0043197]; dendritic spine neck [GO:0044326]; growth cone [GO:0030426]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; polysome [GO:0005844]; postsynaptic density [GO:0014069]; presynapse [GO:0098793] identical protein binding [GO:0042802]; mRNA 3'-UTR binding [GO:0003730]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; translation regulator activity [GO:0045182] 0.10634 1.1543 GPPPAPRPTSR 0 8.64821 0 0 0 0 0 11.0636 0 10.9875 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P51124 GRAM_HUMAN Granzyme M (EC 3.4.21.-) (Met-1 serine protease) (Hu-Met-1) (Met-ase) (Natural killer cell granular protease) GZMM MET1 Homo sapiens (Human) apoptotic process [GO:0006915]; innate immune response [GO:0045087]; killing of cells of another organism [GO:0031640]; proteolysis [GO:0006508]; T cell mediated cytotoxicity [GO:0001913] extracellular region [GO:0005576]; membrane [GO:0016020] serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236] 0.88256 -0.11285 CSMAGWGLTHQGGRLSRVLR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0791 0 0 0 0 0 0 0 0 0 0 0 0 0 P51149 RAB7A_HUMAN Ras-related protein Rab-7a (EC 3.6.5.2) RAB7A RAB7 Homo sapiens (Human) "autophagosome assembly [GO:0000045]; bone resorption [GO:0045453]; early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; endosome to lysosome transport [GO:0008333]; endosome to plasma membrane protein transport [GO:0099638]; epidermal growth factor catabolic process [GO:0007174]; establishment of vesicle localization [GO:0051650]; intracellular transport [GO:0046907]; lipid catabolic process [GO:0016042]; lipophagy [GO:0061724]; negative regulation of exosomal secretion [GO:1903542]; negative regulation of intralumenal vesicle formation [GO:1905366]; phagosome acidification [GO:0090383]; phagosome maturation [GO:0090382]; phagosome-lysosome fusion [GO:0090385]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of viral process [GO:0048524]; protein targeting to lysosome [GO:0006622]; protein to membrane docking [GO:0022615]; protein transport [GO:0015031]; response to bacterium [GO:0009617]; retrograde transport, endosome to Golgi [GO:0042147]; viral release from host cell [GO:0019076]" alveolar lamellar body [GO:0097208]; autophagosome membrane [GO:0000421]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lipid droplet [GO:0005811]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome membrane [GO:0033162]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; phagocytic vesicle [GO:0045335]; phagocytic vesicle membrane [GO:0030670]; phagophore assembly site membrane [GO:0034045]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; synaptic vesicle membrane [GO:0030672] G protein activity [GO:0003925]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; retromer complex binding [GO:1905394]; small GTPase binding [GO:0031267] 0 15.006 ATIGADFLTK 8.68534 8.69905 0 0 0 0 9.31895 9.09932 0 9.41299 11.0035 9.76964 10.8267 11.7081 0 11.0353 10.9598 9.69439 0 0 0 0 0 0 11.2348 9.8874 9.53179 P51153 RAB13_HUMAN Ras-related protein Rab-13 (Cell growth-inhibiting gene 4 protein) RAB13 GIG4 Homo sapiens (Human) bicellular tight junction assembly [GO:0070830]; cellular response to insulin stimulus [GO:0032869]; cortical actin cytoskeleton organization [GO:0030866]; endocytic recycling [GO:0032456]; endosomal transport [GO:0016197]; endothelial cell chemotaxis [GO:0035767]; establishment of Sertoli cell barrier [GO:0097368]; Golgi vesicle fusion to target membrane [GO:0048210]; neuron projection development [GO:0031175]; protein kinase A signaling [GO:0010737]; protein localization to cell leading edge [GO:1902463]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; regulation of exocytosis [GO:0017157]; trans-Golgi network to recycling endosome transport [GO:0044795]; vesicle docking involved in exocytosis [GO:0006904] bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endocytic vesicle [GO:0030139]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; insulin-responsive compartment [GO:0032593]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140] GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.80035 0.23959 LLLIGDSGVGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.911 0 0 0 0 0 0 0 0 P51157 RAB28_HUMAN Ras-related protein Rab-28 RAB28 Homo sapiens (Human) intracellular protein transport [GO:0006886]; toxin transport [GO:1901998] ciliary basal body [GO:0036064]; ciliary rootlet [GO:0035253]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; plasma membrane [GO:0005886] GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.60221 0.44127 ADIVNYNQEPMSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.8025 0 0 0 0 10.6328 0 0 0 0 P51160 PDE6C_HUMAN "Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' (EC 3.1.4.35) (cGMP phosphodiesterase 6C)" PDE6C PDEA2 Homo sapiens (Human) "phototransduction, visible light [GO:0007603]; retinal cone cell development [GO:0046549]; visual perception [GO:0007601]" plasma membrane [GO:0005886] "3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]" 0.27222 0.84121 IIDYILHGK 0 0 0 0 0 0 0 0 0 0 0 0 12.2733 14.974 12.2062 0 0 0 0 0 0 0 0 0 0 10.4402 0 P51170 SCNNG_HUMAN Amiloride-sensitive sodium channel subunit gamma (Epithelial Na(+) channel subunit gamma) (ENaCG) (Gamma-ENaC) (Gamma-NaCH) (Nonvoltage-gated sodium channel 1 subunit gamma) (SCNEG) SCNN1G Homo sapiens (Human) cellular response to acidic pH [GO:0071468]; cellular response to aldosterone [GO:1904045]; cellular response to vasopressin [GO:1904117]; intracellular sodium ion homeostasis [GO:0006883]; multicellular organismal-level water homeostasis [GO:0050891]; regulation of blood pressure [GO:0008217]; sensory perception of salty taste [GO:0050914]; sensory perception of sour taste [GO:0050915]; sodium ion homeostasis [GO:0055078]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] apical plasma membrane [GO:0016324]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; sodium channel complex [GO:0034706] ligand-gated sodium channel activity [GO:0015280]; monoatomic ion channel activity [GO:0005216]; sodium channel activity [GO:0005272]; WW domain binding [GO:0050699] 0.87066 0.05677 NFTLFHHPMHGNCYTFNNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0606 0 0 0 0 0 P51172 SCNND_HUMAN Amiloride-sensitive sodium channel subunit delta (Delta-NaCH) (Epithelial Na(+) channel subunit delta) (Delta-ENaC) (ENaCD) (Nonvoltage-gated sodium channel 1 subunit delta) (SCNED) SCNN1D DNACH Homo sapiens (Human) cellular response to acidic pH [GO:0071468]; cellular response to aldosterone [GO:1904045]; cellular response to vasopressin [GO:1904117]; intracellular sodium ion homeostasis [GO:0006883]; regulation of blood pressure [GO:0008217]; sensory perception of salty taste [GO:0050914]; sensory perception of sour taste [GO:0050915]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] actin cytoskeleton [GO:0015629]; membrane [GO:0016020]; plasma membrane [GO:0005886]; sodium channel complex [GO:0034706] ligand-gated sodium channel activity [GO:0015280] 0.9066 -0.71736 LTWSWCSDHR 0 0 0 0 0 0 0 0 0 9.4572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P51178 PLCD1_HUMAN "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-delta-1) (Phospholipase C-III) (PLC-III) (Phospholipase C-delta-1) (PLC-delta-1)" PLCD1 Homo sapiens (Human) lipid catabolic process [GO:0016042]; phosphatidylinositol metabolic process [GO:0046488]; phosphatidylinositol-mediated signaling [GO:0048015]; phospholipid metabolic process [GO:0006644]; release of sequestered calcium ion into cytosol [GO:0051209] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] "calcium ion binding [GO:0005509]; GTPase activating protein binding [GO:0032794]; phosphatidylinositol phospholipase C activity [GO:0004435]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]" 0.88557 -0.29488 HNVGHLSRIYPAGWR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4133 0 8.64969 0 0 9.54722 0 0 0 0 P51398 RT29_HUMAN "Small ribosomal subunit protein mS29 (28S ribosomal protein S29, mitochondrial) (MRP-S29) (S29mt) (Death-associated protein 3) (DAP-3) (Ionizing radiation resistance conferring protein)" DAP3 MRPS29 Homo sapiens (Human) apoptotic signaling pathway [GO:0097190]; mitochondrial translation [GO:0032543] mitochondrial inner membrane [GO:0005743]; mitochondrial small ribosomal subunit [GO:0005763]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.8987 -0.60403 APTEEGK 0 0 0 0 0 0 9.41827 0 0 0 9.75179 0 8.62593 9.6118 9.26796 10.5137 0 0 0 0 0 9.01853 0 0 0 0 0 P51451 BLK_HUMAN Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk) BLK Homo sapiens (Human) B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of insulin secretion [GO:0032024]; positive regulation of protein binding [GO:0032092]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234] ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102] 0.16393 0.98415 GAFSLSVKDVTTQGELIK 0 0 11.0025 0 0 0 0 0 0 9.44483 9.04234 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P51452 DUS3_HUMAN Dual specificity protein phosphatase 3 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase VHR) (Vaccinia H1-related phosphatase) (VHR) DUSP3 VHR Homo sapiens (Human) cellular response to epidermal growth factor stimulus [GO:0071364]; dephosphorylation [GO:0016311]; negative regulation of cell migration [GO:0030336]; negative regulation of chemotaxis [GO:0050922]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of JNK cascade [GO:0046329]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of T cell activation [GO:0050868]; negative regulation of T cell receptor signaling pathway [GO:0050860]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; positive regulation of focal adhesion disassembly [GO:0120183]; positive regulation of mitotic cell cycle [GO:0045931]; regulation of focal adhesion assembly [GO:0051893] cytoplasm [GO:0005737]; cytosol [GO:0005829]; immunological synapse [GO:0001772]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] cytoskeletal protein binding [GO:0008092]; MAP kinase phosphatase activity [GO:0033549]; myosin phosphatase activity [GO:0017018]; phosphatase activity [GO:0016791]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; receptor tyrosine kinase binding [GO:0030971] 0.93312 -1.2881 SALSIVR 0 0 0 0 0 0 0 9.65859 9.84649 0 10.0225 0 0 0 9.52227 9.83336 9.78239 9.53072 0 0 0 9.96563 0 0 0 0 0 P51508 ZNF81_HUMAN Zinc finger protein 81 (HFZ20) ZNF81 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.95938 -1.8424 CSECGKAFTQKSTLR 0 9.62925 9.66598 0 0 0 0 10.4778 9.5378 0 0 0 0 0 0 0 0 0 8.67951 0 0 0 0 0 0 0 0 P51511 MMP15_HUMAN Matrix metalloproteinase-15 (MMP-15) (EC 3.4.24.-) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP) (SMCP-2) MMP15 Homo sapiens (Human) collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; protein modification process [GO:0036211]; proteolysis [GO:0006508]; response to estradiol [GO:0032355] extracellular matrix [GO:0031012]; plasma membrane [GO:0005886] enzyme activator activity [GO:0008047]; metalloaminopeptidase activity [GO:0070006]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270] 0.8693 0.068001 LYGYLPQPSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0257 0 0 0 0 0 0 0 0 0 P51513 NOVA1_HUMAN RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1) (Onconeural ventral antigen 1) (Paraneoplastic Ri antigen) (Ventral neuron-specific protein 1) NOVA1 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; negative regulation of cold-induced thermogenesis [GO:0120163]; nervous system development [GO:0007399]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]" cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; sequence-specific mRNA binding [GO:1990825] 0.7243 0.35536 ITYEQGVRAANPQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.00941 0 0 0 0 0 0 0 0 P51530 DNA2_HUMAN DNA replication ATP-dependent helicase/nuclease DNA2 (hDNA2) (DNA replication ATP-dependent helicase-like homolog) [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)] DNA2 DNA2L KIAA0083 Homo sapiens (Human) "base-excision repair [GO:0006284]; DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; DNA replication checkpoint signaling [GO:0000076]; DNA replication, Okazaki fragment processing [GO:0033567]; DNA replication, removal of RNA primer [GO:0043137]; G-quadruplex DNA unwinding [GO:0044806]; mitochondrial DNA repair [GO:0043504]; mitochondrial DNA replication [GO:0006264]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of DNA replication [GO:0045740]; replication fork reversal [GO:0071932]; t-circle formation [GO:0090656]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]" "chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]" "4 iron, 4 sulfur cluster binding [GO:0051539]; 5'-3' DNA helicase activity [GO:0043139]; 5'-flap endonuclease activity [GO:0017108]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; helicase activity [GO:0004386]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; RNA binding [GO:0003723]; single-stranded DNA helicase activity [GO:0017116]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]" 0.59204 0.45516 AVLSETFR 0 0 10.1678 0 10.7148 0 10.7115 10.8289 0 0 0 9.78013 14.6553 0 9.30827 10.1538 9.63134 0 0 0 0 0 0 0 0 0 0 P51531 SMCA2_HUMAN Probable global transcription activator SNF2L2 (EC 3.6.4.-) (ATP-dependent helicase SMARCA2) (BRG1-associated factor 190B) (BAF190B) (Protein brahma homolog) (hBRM) (SNF2-alpha) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2) SMARCA2 BAF190B BRM SNF2A SNF2L2 Homo sapiens (Human) chromatin remodeling [GO:0006338]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatid development [GO:0007286] bBAF complex [GO:0140092]; brahma complex [GO:0035060]; chromatin [GO:0000785]; GBAF complex [GO:0140288]; intermediate filament cytoskeleton [GO:0045111]; intracellular membrane-bounded organelle [GO:0043231]; nBAF complex [GO:0071565]; npBAF complex [GO:0071564]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SWI/SNF complex [GO:0016514] "ATP binding [GO:0005524]; ATP-dependent activity, acting on DNA [GO:0008094]; ATP-dependent chromatin remodeler activity [GO:0140658]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; helicase activity [GO:0004386]; histone binding [GO:0042393]; hydrolase activity [GO:0016787]; transcription cis-regulatory region binding [GO:0000976]; transcription coactivator activity [GO:0003713]" 0.96744 -2.8514 DKHILAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.78991 0 0 0 0 0 0 0 0 0 0 P51532 SMCA4_HUMAN Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Mitotic growth and transcription activator) (Protein BRG-1) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4) SMARCA4 BAF190A BRG1 SNF2B SNF2L4 Homo sapiens (Human) chromatin remodeling [GO:0006338]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell growth [GO:0030308]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; neural retina development [GO:0003407]; nucleosome disassembly [GO:0006337]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of glucose mediated signaling pathway [GO:1902661]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901838]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA polymerase I preinitiation complex assembly [GO:0001188]; transcription initiation-coupled chromatin remodeling [GO:0045815] bBAF complex [GO:0140092]; chromatin [GO:0000785]; extracellular space [GO:0005615]; fibrillar center [GO:0001650]; GBAF complex [GO:0140288]; kinetochore [GO:0000776]; membrane [GO:0016020]; nBAF complex [GO:0071565]; npBAF complex [GO:0071564]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; RSC-type complex [GO:0016586]; SWI/SNF complex [GO:0016514] "ATP binding [GO:0005524]; ATP-dependent activity, acting on DNA [GO:0008094]; ATP-dependent chromatin remodeler activity [GO:0140658]; DNA binding [GO:0003677]; DNA polymerase binding [GO:0070182]; helicase activity [GO:0004386]; hydrolase activity [GO:0016787]; lysine-acetylated histone binding [GO:0070577]; nuclear androgen receptor binding [GO:0050681]; p53 binding [GO:0002039]; RNA binding [GO:0003723]; Tat protein binding [GO:0030957]; transcription coactivator activity [GO:0003713]; transcription coregulator binding [GO:0001221]; transcription corepressor activity [GO:0003714]" 0.96872 -11.324 DKDDESK 0 0 0 10.3476 10.4025 10.3939 0 10.1871 0 0 0 9.94827 0 0 12.4752 8.60988 0 0 8.8661 0 0 8.91013 0 0 0 0 0 P51570 GALK1_HUMAN Galactokinase (EC 2.7.1.6) (Galactose kinase) GALK1 GALK Homo sapiens (Human) galactitol metabolic process [GO:0019402]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; glycolytic process from galactose [GO:0061623] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020] ATP binding [GO:0005524]; galactokinase activity [GO:0004335]; galactose binding [GO:0005534] 0.93156 -1.2721 RRQCEEVAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.72207 0 0 P51571 SSRD_HUMAN Translocon-associated protein subunit delta (TRAP-delta) (Signal sequence receptor subunit delta) (SSR-delta) SSR4 TRAPD Homo sapiens (Human) endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; Sec61 translocon complex [GO:0005784] 0.0611 1.3492 FFDEESYSLLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.13206 0 0 0 0 0 0 0 0 P51572 BAP31_HUMAN B-cell receptor-associated protein 31 (BCR-associated protein 31) (Bap31) (6C6-AG tumor-associated antigen) (Protein CDM) (p28) BCAP31 BAP31 DXS1357E Homo sapiens (Human) "apoptotic process [GO:0006915]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903071]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of retrograde protein transport, ER to cytosol [GO:1904154]; protein localization to endoplasmic reticulum exit site [GO:0070973]; protein targeting to mitochondrion [GO:0006626]; response to endoplasmic reticulum stress [GO:0034976]; spermatogenesis [GO:0007283]" clathrin-coated vesicle [GO:0030136]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; lipid droplet [GO:0005811]; lumenal side of endoplasmic reticulum membrane [GO:0098553]; membrane [GO:0016020]; mitochondria-associated endoplasmic reticulum membrane [GO:0044233]; mitochondrion [GO:0005739]; perinuclear endoplasmic reticulum [GO:0097038]; plasma membrane [GO:0005886] MHC class I protein binding [GO:0042288]; protein-containing complex binding [GO:0044877] 0 27.603 AENQVLAMR 0 0 0 0 0 0 0 9.84004 0 0 0 0 0 9.31533 0 8.92092 0 0 9.27361 0 9.44626 8.97375 9.25061 8.95748 10.8577 0 0 P51580 TPMT_HUMAN Thiopurine S-methyltransferase (EC 2.1.1.67) (Thiopurine methyltransferase) TPMT Homo sapiens (Human) methylation [GO:0032259]; nucleobase-containing compound metabolic process [GO:0006139]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805] cytosol [GO:0005829] S-adenosyl-L-methionine binding [GO:1904047]; thiopurine S-methyltransferase activity [GO:0008119] 0.96777 -2.8707 ICNIRCLEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.73676 0 10.2744 0 0 0 0 0 0 9.95518 0 0 0 P51587 BRCA2_HUMAN Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein) BRCA2 FACD FANCD1 Homo sapiens (Human) "brain development [GO:0007420]; cellular response to ionizing radiation [GO:0071479]; cellular senescence [GO:0090398]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; establishment of protein localization to telomere [GO:0070200]; female gonad development [GO:0008585]; hematopoietic stem cell proliferation [GO:0071425]; histone H2A monoubiquitination [GO:0035518]; inner cell mass cell proliferation [GO:0001833]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; male meiosis I [GO:0007141]; mitotic recombination-dependent replication fork processing [GO:1990426]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; nucleotide-excision repair [GO:0006289]; oocyte maturation [GO:0001556]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mitotic cell cycle [GO:0045931]; protein autoubiquitination [GO:0051865]; regulation of cytokinesis [GO:0032465]; regulation of DNA damage checkpoint [GO:2000001]; regulation of DNA-templated transcription [GO:0006355]; response to gamma radiation [GO:0010332]; response to UV-C [GO:0010225]; response to X-ray [GO:0010165]; spermatogenesis [GO:0007283]; telomere maintenance via recombination [GO:0000722]" "BRCA2-MAGE-D1 complex [GO:0033593]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; DNA repair complex [GO:1990391]; lateral element [GO:0000800]; nuclear ubiquitin ligase complex [GO:0000152]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]" gamma-tubulin binding [GO:0043015]; histone H3 acetyltransferase activity [GO:0010484]; histone H4 acetyltransferase activity [GO:0010485]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; single-stranded DNA binding [GO:0003697] 0.96858 -8.0212 ALQDGAELYEAVK 13.7947 0 0 0 0 0 11.2163 0 11.0674 11.0045 8.35147 9.41386 0 0 0 9.29027 0 0 0 11.227 9.49464 0 0 0 0 8.90803 9.143 P51589 CP2J2_HUMAN Cytochrome P450 2J2 (EC 1.14.14.-) (Albendazole monooxygenase (hydroxylating)) (EC 1.14.14.74) (Albendazole monooxygenase (sulfoxide-forming)) (EC 1.14.14.73) (Arachidonic acid epoxygenase) (CYPIIJ2) (Hydroperoxy icosatetraenoate isomerase) (EC 5.4.4.7) CYP2J2 Homo sapiens (Human) epoxygenase P450 pathway [GO:0019373]; fatty acid metabolic process [GO:0006631]; icosanoid metabolic process [GO:0006690]; linoleic acid metabolic process [GO:0043651]; organic acid metabolic process [GO:0006082]; regulation of heart contraction [GO:0008016]; xenobiotic metabolic process [GO:0006805] cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231] "arachidonic acid 11,12-epoxygenase activity [GO:0008405]; arachidonic acid 14,15-epoxygenase activity [GO:0008404]; arachidonic acid 5,6-epoxygenase activity [GO:0106301]; arachidonic acid epoxygenase activity [GO:0008392]; heme binding [GO:0020037]; hydroperoxy icosatetraenoate isomerase activity [GO:0106255]; iron ion binding [GO:0005506]; isomerase activity [GO:0016853]; linoleic acid epoxygenase activity [GO:0071614]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]" 0.87023 0.033905 EAFMPFSIGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.7449 0 0 0 0 0 0 9.65592 0 0 P51606 RENBP_HUMAN N-acylglucosamine 2-epimerase (AGE) (EC 5.1.3.8) (GlcNAc 2-epimerase) (N-acetyl-D-glucosamine 2-epimerase) (Renin-binding protein) (RnBP) RENBP Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; N-acetylglucosamine metabolic process [GO:0006044]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]; negative regulation of endopeptidase activity [GO:0010951]; regulation of blood pressure [GO:0008217] cytosol [GO:0005829]; extracellular exosome [GO:0070062] ATP binding [GO:0005524]; endopeptidase inhibitor activity [GO:0004866]; identical protein binding [GO:0042802]; N-acylglucosamine 2-epimerase activity [GO:0050121]; peptidase inhibitor activity [GO:0030414] 0.95441 -1.5111 EGRVYDDLK 0 0 0 0 0 0 0 0 0 0 9.33617 0 0 0 0 0 0 0 0 0 0 12.0474 0 0 0 0 0 P51608 MECP2_HUMAN Methyl-CpG-binding protein 2 (MeCp-2 protein) (MeCp2) MECP2 Homo sapiens (Human) adult locomotory behavior [GO:0008344]; behavioral fear response [GO:0001662]; biogenic amine metabolic process [GO:0006576]; cardiolipin metabolic process [GO:0032048]; catecholamine secretion [GO:0050432]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; excitatory postsynaptic potential [GO:0060079]; glial cell proliferation [GO:0014009]; glucocorticoid metabolic process [GO:0008211]; glutamine metabolic process [GO:0006541]; heterochromatin formation [GO:0031507]; histone acetylation [GO:0016573]; histone methylation [GO:0016571]; inositol metabolic process [GO:0006020]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; mitotic spindle organization [GO:0007052]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation [GO:2000820]; nervous system process involved in regulation of systemic arterial blood pressure [GO:0001976]; neuron maturation [GO:0042551]; Notch signaling pathway [GO:0007219]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA methylation [GO:1905643]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of histone H3-K9 trimethylation [GO:1900114]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proprioception [GO:0019230]; protein localization [GO:0008104]; regulation of gene expression by genomic imprinting [GO:0006349]; regulation of respiratory gaseous exchange by nervous system process [GO:0002087]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to hypoxia [GO:0001666]; response to other organism [GO:0051707]; sensory perception of pain [GO:0019233]; social behavior [GO:0035176]; startle response [GO:0001964]; synapse assembly [GO:0007416]; trans-synaptic signaling by BDNF [GO:0099191]; ventricular system development [GO:0021591]; visual learning [GO:0008542] centrosome [GO:0005813]; cytosol [GO:0005829]; extracellular space [GO:0005615]; heterochromatin [GO:0000792]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; double-stranded methylated DNA binding [GO:0010385]; methyl-CpG binding [GO:0008327]; molecular adaptor activity [GO:0060090]; molecular condensate scaffold activity [GO:0140693]; mRNA binding [GO:0003729]; nucleic acid binding [GO:0003676]; promoter-specific chromatin binding [GO:1990841]; RNA binding [GO:0003723]; siRNA binding [GO:0035197]; transcription corepressor activity [GO:0003714] 0.94803 -1.3597 MPRGGSLESDGCPKEPAK 0 0 0 0 0 0 0 0 13.9813 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P51617 IRAK1_HUMAN Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1) IRAK1 IRAK Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; aging [GO:0007568]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; interleukin-1-mediated signaling pathway [GO:0070498]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of type I interferon production [GO:0032481]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cytokine-mediated signaling pathway [GO:0001959]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; toll-like receptor 2 signaling pathway [GO:0034134]; toll-like receptor 4 signaling pathway [GO:0034142]; toll-like receptor 9 signaling pathway [GO:0034162]; toll-like receptor signaling pathway [GO:0002224]; type I interferon-mediated signaling pathway [GO:0060337] cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] ATP binding [GO:0005524]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; NF-kappaB-inducing kinase activity [GO:0004704]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.97001 -4.1437 DQTELRLCER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.20679 0 0 0 0 0 0 0 0 0 P51648 AL3A2_HUMAN Aldehyde dehydrogenase family 3 member A2 (EC 1.2.1.3) (EC 1.2.1.94) (Aldehyde dehydrogenase 10) (Fatty aldehyde dehydrogenase) (Microsomal aldehyde dehydrogenase) ALDH3A2 ALDH10 FALDH Homo sapiens (Human) cellular aldehyde metabolic process [GO:0006081]; central nervous system development [GO:0007417]; epidermis development [GO:0008544]; fatty acid metabolic process [GO:0006631]; hexadecanal metabolic process [GO:0046458]; peripheral nervous system development [GO:0007422]; phytol metabolic process [GO:0033306]; sesquiterpenoid metabolic process [GO:0006714] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777] 3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; long-chain-alcohol oxidase activity [GO:0046577]; long-chain-aldehyde dehydrogenase activity [GO:0050061]; medium-chain-aldehyde dehydrogenase activity [GO:0052814]; protein homodimerization activity [GO:0042803] 0.92174 -1.136 MVQEREK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.88379 0 0 0 P51649 SSDH_HUMAN "Succinate-semialdehyde dehydrogenase, mitochondrial (EC 1.2.1.24) (Aldehyde dehydrogenase family 5 member A1) (NAD(+)-dependent succinic semialdehyde dehydrogenase)" ALDH5A1 SSADH Homo sapiens (Human) central nervous system development [GO:0007417]; gamma-aminobutyric acid catabolic process [GO:0009450]; glutamate metabolic process [GO:0006536]; neurotransmitter catabolic process [GO:0042135]; post-embryonic development [GO:0009791]; succinate metabolic process [GO:0006105] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] identical protein binding [GO:0042802]; succinate-semialdehyde dehydrogenase (NAD+) activity [GO:0004777] 0.90537 -0.72892 EVGEAICTDPLVSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9558 10.7687 0 0 0 0 0 0 0 0 0 0 P51659 DHB4_HUMAN "Peroxisomal multifunctional enzyme type 2 (MFE-2) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) (D-bifunctional protein) (DBP) (Multifunctional protein 2) (MFP-2) (Short chain dehydrogenase/reductase family 8C member 1) [Cleaved into: (3R)-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12); Enoyl-CoA hydratase 2 (EC 4.2.1.107) (EC 4.2.1.119) (3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase)]" HSD17B4 EDH17B4 SDR8C1 Homo sapiens (Human) androgen metabolic process [GO:0008209]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; medium-chain fatty-acyl-CoA metabolic process [GO:0036112]; osteoblast differentiation [GO:0001649]; Sertoli cell development [GO:0060009]; very long-chain fatty acid metabolic process [GO:0000038]; very long-chain fatty-acyl-CoA metabolic process [GO:0036111] cytosol [GO:0005829]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777] "(3R)-hydroxyacyl-CoA dehydrogenase (NAD) activity [GO:0106386]; 17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; 3-hydroxyacyl-CoA dehydratase activity [GO:0018812]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity [GO:0033989]; enoyl-CoA hydratase activity [GO:0004300]; estradiol 17-beta-dehydrogenase [NAD(P)] activity [GO:0004303]; isomerase activity [GO:0016853]; protein homodimerization activity [GO:0042803]" 0 7.5924 ATSTATSGFAGAIGQK 0 0 0 0 0 0 0 8.99743 9.14794 0 10.3425 0 0 9.92041 0 0 0 0 0 0 0 10.9284 0 0 10.9151 10.9047 10.259 P51668 UB2D1_HUMAN Ubiquitin-conjugating enzyme E2 D1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D1) (Stimulator of Fe transport) (SFT) (UBC4/5 homolog) (UbcH5) (Ubiquitin carrier protein D1) (Ubiquitin-conjugating enzyme E2(17)KB 1) (Ubiquitin-conjugating enzyme E2-17 kDa 1) (Ubiquitin-protein ligase D1) UBE2D1 SFT UBC5A UBCH5 UBCH5A Homo sapiens (Human) negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of protein polyubiquitination [GO:1902916]; positive regulation of protein ubiquitination [GO:0031398]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151] ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842] 0.92375 -1.0468 SDKEKYNR 9.68452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.94269 0 0 0 0 0 0 0 0 0 0 P51679 CCR4_HUMAN C-C chemokine receptor type 4 (C-C CKR-4) (CC-CKR-4) (CCR-4) (CCR4) (K5-5) (CD antigen CD194) CCR4 CMKBR4 Homo sapiens (Human) chemotaxis [GO:0006935]; homeostasis of number of cells [GO:0048872]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interneuron migration [GO:1904936]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of positive chemotaxis [GO:0050927]; response to antibiotic [GO:0046677]; response to bacterium [GO:0009617]; response to radiation [GO:0009314]; tolerance induction [GO:0002507] external side of plasma membrane [GO:0009897]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886] C-C chemokine receptor activity [GO:0016493]; chemokine receptor activity [GO:0004950] 0.95456 -1.5122 NHTYCKTK 0 0 0 0 0 0 0 0 0 9.7699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P51687 SUOX_HUMAN "Sulfite oxidase, mitochondrial (EC 1.8.3.1)" SUOX Homo sapiens (Human) sulfur compound metabolic process [GO:0006790] mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482] 0.95119 -1.4385 GVLSNAWHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1551 10.0174 0 0 0 0 0 0 0 0 P51688 SPHM_HUMAN N-sulphoglucosamine sulphohydrolase (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase) SGSH HSS Homo sapiens (Human) determination of adult lifespan [GO:0008340]; glycosaminoglycan catabolic process [GO:0006027]; heparan sulfate proteoglycan catabolic process [GO:0030200]; motor behavior [GO:0061744] extracellular exosome [GO:0070062]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764] metal ion binding [GO:0046872]; N-sulfoglucosamine sulfohydrolase activity [GO:0016250]; sulfuric ester hydrolase activity [GO:0008484] 0.88647 -0.36244 ADLAAQYTTVGR 12.9899 12.8506 12.8119 0 11.6434 0 0 13.2447 0 0 0 0 0 0 11.6944 0 0 0 0 0 0 0 0 0 0 0 0 P51692 STA5B_HUMAN Signal transducer and activator of transcription 5B STAT5B Homo sapiens (Human) activated T cell proliferation [GO:0050798]; B cell differentiation [GO:0030183]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hormone stimulus [GO:0032870]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; development of secondary female sexual characteristics [GO:0046543]; development of secondary male sexual characteristics [GO:0046544]; erythrocyte differentiation [GO:0030218]; female pregnancy [GO:0007565]; gamma-delta T cell differentiation [GO:0042492]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; lactation [GO:0007595]; lipid storage [GO:0019915]; luteinization [GO:0001553]; mast cell migration [GO:0097531]; mitotic cell cycle [GO:0000278]; myeloid cell apoptotic process [GO:0033028]; natural killer cell differentiation [GO:0001779]; natural killer cell mediated cytotoxicity [GO:0042267]; natural killer cell proliferation [GO:0001787]; negative regulation of erythrocyte differentiation [GO:0045647]; negative regulation of myeloid cell apoptotic process [GO:0033033]; Peyer's patch development [GO:0048541]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gamma-delta T cell differentiation [GO:0045588]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of transcription by RNA polymerase II [GO:0045944]; progesterone metabolic process [GO:0042448]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of cell population proliferation [GO:0042127]; regulation of epithelial cell differentiation [GO:0030856]; regulation of multicellular organism growth [GO:0040014]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription by RNA polymerase II [GO:0006357]; response to estradiol [GO:0032355]; response to interleukin-15 [GO:0070672]; response to interleukin-2 [GO:0070669]; response to interleukin-4 [GO:0070670]; response to peptide hormone [GO:0043434]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; taurine metabolic process [GO:0019530]; transcription by RNA polymerase II [GO:0006366] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575] "chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; nuclear glucocorticoid receptor binding [GO:0035259]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.55935 0.52517 EAQTLQQYRVELAEK 10.3361 0 0 0 0 0 0 9.21497 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4934 0 10.55 P51693 APLP1_HUMAN Amyloid beta precursor like protein 1 (Amyloid beta (A4) precursor-like protein 1) (Amyloid-like protein 1) (APLP) (APLP-1) [Cleaved into: C30] APLP1 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; cellular response to norepinephrine stimulus [GO:0071874]; central nervous system development [GO:0007417]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; mRNA polyadenylation [GO:0006378]; negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0106072]; nervous system development [GO:0007399]; regulation of translation [GO:0006417] basement membrane [GO:0005604]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] alpha-2A adrenergic receptor binding [GO:0031694]; alpha-2B adrenergic receptor binding [GO:0031695]; alpha-2C adrenergic receptor binding [GO:0031696]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914] 0.9281 -1.2262 EQRHTLR 0 0 0 0 0 0 0 0 0 0 10.5621 0 0 0 0 0 0 0 0 0 10.5111 0 0 0 0 0 0 P51784 UBP11_HUMAN Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.4.19.12) (Deubiquitinating enzyme 11) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) USP11 UHX1 Homo sapiens (Human) protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] chromosome [GO:0005694]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] cysteine-type deubiquitinase activity [GO:0004843]; cysteine-type endopeptidase activity [GO:0004197]; transcription corepressor binding [GO:0001222] 0.83525 0.1906 VIELPNIQK 0 0 0 0 0 0 0 0 0 0 0 8.22564 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P51790 CLCN3_HUMAN H(+)/Cl(-) exchange transporter 3 (Chloride channel protein 3) (ClC-3) (Chloride transporter ClC-3) CLCN3 Homo sapiens (Human) "adult locomotory behavior [GO:0008344]; chloride transmembrane transport [GO:1902476]; endosomal lumen acidification [GO:0048388]; negative regulation of cell volume [GO:0045794]; phagocytosis, engulfment [GO:0006911]; photoreceptor cell maintenance [GO:0045494]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; regulation of pH [GO:0006885]; synaptic transmission, GABAergic [GO:0051932]; synaptic transmission, glutamatergic [GO:0035249]; synaptic vesicle lumen acidification [GO:0097401]" apical plasma membrane [GO:0016324]; axon terminus [GO:0043679]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; external side of plasma membrane [GO:0009897]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; inhibitory synapse [GO:0060077]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; recycling endosome [GO:0055037]; ruffle membrane [GO:0032587]; secretory granule [GO:0030141]; specific granule [GO:0042581]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; vesicle membrane [GO:0012506] antiporter activity [GO:0015297]; ATP binding [GO:0005524]; chloride channel activity [GO:0005254]; PDZ domain binding [GO:0030165]; voltage-gated chloride channel activity [GO:0005247]; volume-sensitive chloride channel activity [GO:0072320] 0.73366 0.33007 EGIYEAHIR 9.07436 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P51793 CLCN4_HUMAN H(+)/Cl(-) exchange transporter 4 (Chloride channel protein 4) (ClC-4) (Chloride transporter ClC-4) CLCN4 Homo sapiens (Human) chloride transport [GO:0006821]; monoatomic ion transmembrane transport [GO:0034220]; non-motile cilium assembly [GO:1905515] ciliary base [GO:0097546]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; synaptic vesicle [GO:0008021] antiporter activity [GO:0015297]; ATP binding [GO:0005524]; chloride channel activity [GO:0005254]; voltage-gated chloride channel activity [GO:0005247] 0.81875 0.21847 TLATDVMRPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4466 0 0 0 0 0 P51795 CLCN5_HUMAN H(+)/Cl(-) exchange transporter 5 (Chloride channel protein 5) (ClC-5) (Chloride transporter ClC-5) CLCN5 CLCK2 Homo sapiens (Human) chloride transport [GO:0006821]; endocytosis [GO:0006897]; monoatomic ion transmembrane transport [GO:0034220]; renal system process [GO:0003014] apical part of cell [GO:0045177]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; synaptic vesicle [GO:0008021] antiporter activity [GO:0015297]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; voltage-gated chloride channel activity [GO:0005247] 0.91755 -0.85325 DVLKHIAQMANQDPDSILFN 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.84696 0 0 0 0 P51798 CLCN7_HUMAN H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7) CLCN7 Homo sapiens (Human) response to pH [GO:0009268]; transepithelial chloride transport [GO:0030321] chloride channel complex [GO:0034707]; cytoplasmic vesicle [GO:0031410]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; membrane [GO:0016020] antiporter activity [GO:0015297]; ATP binding [GO:0005524]; chloride channel activity [GO:0005254]; chloride transmembrane transporter activity [GO:0015108]; voltage-gated chloride channel activity [GO:0005247] 0.96957 -3.5807 IFEYFRRDTEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.79393 0 0 P51801 CLCKB_HUMAN Chloride channel protein ClC-Kb (Chloride channel Kb) (ClC-K2) CLCNKB Homo sapiens (Human) chloride transport [GO:0006821]; regulation of monoatomic ion transmembrane transport [GO:0034765]; renal absorption [GO:0070293]; renal sodium ion absorption [GO:0070294]; transepithelial chloride transport [GO:0030321] chloride channel complex [GO:0034707]; plasma membrane [GO:0005886] metal ion binding [GO:0046872]; voltage-gated chloride channel activity [GO:0005247] 0.80943 0.22736 AISNLTNPPAPK 0 0 0 0 0 9.43033 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P51805 PLXA3_HUMAN Plexin-A3 (Plexin-4) (Semaphorin receptor SEX) PLXNA3 PLXN4 SEX Homo sapiens (Human) axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; branchiomotor neuron axon guidance [GO:0021785]; facial nerve structural organization [GO:0021612]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hippocampus development [GO:0021766]; negative chemotaxis [GO:0050919]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; neuron projection guidance [GO:0097485]; olfactory nerve formation [GO:0021628]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cytoskeleton organization [GO:0051495]; pyramidal neuron development [GO:0021860]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; trigeminal nerve structural organization [GO:0021637] plasma membrane [GO:0005886]; semaphorin receptor complex [GO:0002116] semaphorin receptor activity [GO:0017154] 0.51203 0.60385 GIPYSQRPK 0 0 8.69943 0 8.37295 8.29108 0 8.79944 0 0 0 0 0 0 0 8.626 8.78428 0 0 0 0 0 0 0 0 0 9.44479 P51812 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) RPS6KA3 ISPK1 MAPKAPK1B RSK2 Homo sapiens (Human) cell cycle [GO:0007049]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; intracellular signal transduction [GO:0035556]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell growth [GO:0030307]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of translation in response to stress [GO:0043555]; response to lipopolysaccharide [GO:0032496]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; toll-like receptor signaling pathway [GO:0002224] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; synapse [GO:0045202] ATP binding [GO:0005524]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; magnesium ion binding [GO:0000287]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; ribosomal protein S6 kinase activity [GO:0004711] 0.91882 -0.89657 GAMAATYSALNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.12107 0 0 0 10.2647 0 0 0 0 0 10.5762 P51814 ZNF41_HUMAN Zinc finger protein 41 ZNF41 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96909 -3.9894 CGKAFIQK 0 0 0 0 9.36652 0 10.7304 0 0 10.4892 0 0 0 0 0 0 11.3293 0 0 0 0 0 0 0 0 0 0 P51816 AFF2_HUMAN AF4/FMR2 family member 2 (Protein FMR-2) (FMR2P) (Protein Ox19) AFF2 FMR2 OX19 Homo sapiens (Human) brain development [GO:0007420]; learning or memory [GO:0007611]; mRNA processing [GO:0006397]; negative regulation of gene expression [GO:0010629]; nuclear speck organization [GO:0035063]; regulation of gene expression [GO:0010468]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] nuclear speck [GO:0016607] G-quadruplex RNA binding [GO:0002151] 0.9555 -1.6366 GYEHWDMADK 8.649 0 0 0 0 0 11.6473 8.85234 0 0 0 0 0 0 0 0 0 0 0 0 0 9.31039 0 0 0 0 0 P51817 PRKX_HUMAN cAMP-dependent protein kinase catalytic subunit PRKX (PrKX) (Protein kinase X) (Protein kinase X-linked) (Serine/threonine-protein kinase PRKX) (EC 2.7.11.1) (Protein kinase PKX1) PRKX PKX1 Homo sapiens (Human) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; endothelial cell migration [GO:0043542]; endothelial cell proliferation [GO:0001935]; epithelial tube morphogenesis [GO:0060562]; kidney morphogenesis [GO:0060993]; myeloid cell differentiation [GO:0030099]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of epithelial cell differentiation involved in kidney development [GO:2000696] cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; cAMP-dependent protein kinase activity [GO:0004691]; protein serine kinase activity [GO:0106310] 0.84746 0.16835 EVSHPFLIR 10.4592 0 10.3859 0 0 0 10.4871 10.5022 10.5809 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.481 P51825 AFF1_HUMAN AF4/FMR2 family member 1 (ALL1-fused gene from chromosome 4 protein) (Protein AF-4) (Protein FEL) (Proto-oncogene AF4) AFF1 AF4 FEL MLLT2 PBM1 Homo sapiens (Human) regulation of gene expression [GO:0010468] super elongation complex [GO:0032783]; transcription elongation factor complex [GO:0008023] 0.96285 -2.5272 ASARAGSRTSLQGER 0 0 0 0 0 7.80239 0 0 0 0 0 0 0 10.5628 0 11.8135 0 0 0 9.50696 0 0 0 0 0 0 0 P51826 AFF3_HUMAN AF4/FMR2 family member 3 (Lymphoid nuclear protein related to AF4) (Protein LAF-4) AFF3 LAF4 Homo sapiens (Human) embryonic hindlimb morphogenesis [GO:0035116]; regulation of gene expression [GO:0010468]; response to tumor necrosis factor [GO:0034612] cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; super elongation complex [GO:0032783] DNA-binding transcription factor activity [GO:0003700]; double-stranded DNA binding [GO:0003690] 0.92414 -1.0094 QLAALCYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.59081 0 0 0 0 0 0 P51841 GUC2F_HUMAN "Retinal guanylyl cyclase 2 (RETGC-2) (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (Guanylate cyclase F) (GC-F) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2)" GUCY2F GUC2F RETGC2 Homo sapiens (Human) cGMP biosynthetic process [GO:0006182]; cGMP-mediated signaling [GO:0019934]; detection of light stimulus involved in visual perception [GO:0050908]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; visual perception [GO:0007601] nuclear outer membrane [GO:0005640]; photoreceptor disc membrane [GO:0097381]; plasma membrane [GO:0005886]; rod photoreceptor outer segment [GO:0120200] ATP binding [GO:0005524]; GTP binding [GO:0005525]; guanylate cyclase activity [GO:0004383]; identical protein binding [GO:0042802]; peptide receptor activity [GO:0001653]; protein kinase activity [GO:0004672]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023] 0.92425 -1.0035 ALPEVAARLAIER 0 9.34119 0 9.85269 0 0 0 0 0 10.8791 0 0 0 9.49019 0 11.4896 0 0 0 0 0 0 0 0 0 0 0 P51857 AK1D1_HUMAN Aldo-keto reductase family 1 member D1 (EC 1.3.1.3) (3-oxo-5-beta-steroid 4-dehydrogenase) (Delta(4)-3-ketosteroid 5-beta-reductase) (Delta(4)-3-oxosteroid 5-beta-reductase) AKR1D1 SRD5B1 Homo sapiens (Human) androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; bile acid catabolic process [GO:0030573]; C21-steroid hormone metabolic process [GO:0008207]; cholesterol catabolic process [GO:0006707]; digestion [GO:0007586] cytosol [GO:0005829] alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; ketosteroid monooxygenase activity [GO:0047086]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229] 0.0059347 2.4366 SLGVSNFNR 0 0 0 0 0 0 0 0 0 10.4807 10.7889 0 9.98413 11.1003 11.0291 9.97599 10.2857 9.94727 0 0 0 0 0 0 0 0 0 P51858 HDGF_HUMAN Hepatoma-derived growth factor (HDGF) (High mobility group protein 1-like 2) (HMG-1L2) HDGF HMG1L2 Homo sapiens (Human) cellular response to interleukin-7 [GO:0098761]; chromatin remodeling [GO:0006338]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell division [GO:0051781]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to nucleus [GO:0034504]; signal transduction [GO:0007165] collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription repressor complex [GO:0017053] "actin binding [GO:0003779]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; nucleotide binding [GO:0000166]; RNA binding [GO:0003723]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; transcription corepressor activity [GO:0003714]; transcription corepressor binding [GO:0001222]; tubulin binding [GO:0015631]" 0.84758 0.17292 EAENPEGEEK 0 12.1662 0 0 0 0 0 0 0 0 9.79727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P51956 NEK3_HUMAN Serine/threonine-protein kinase Nek3 (EC 2.7.11.1) (HSPK 36) (Never in mitosis A-related kinase 3) (NimA-related protein kinase 3) NEK3 Homo sapiens (Human) cell division [GO:0051301]; establishment of cell polarity [GO:0030010]; mitotic cell cycle [GO:0000278]; neuron projection morphogenesis [GO:0048812]; protein phosphorylation [GO:0006468]; regulation of tubulin deacetylation [GO:0090043] axon [GO:0030424]; cytoplasm [GO:0005737]; nucleus [GO:0005634] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.84216 0.1774 NPSHRPSATTLLSR 10.663 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P51957 NEK4_HUMAN Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase 4) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2) NEK4 STK2 Homo sapiens (Human) cell division [GO:0051301]; DNA damage response [GO:0006974]; mitotic cell cycle [GO:0000278]; positive regulation of DNA-templated transcription [GO:0045893]; protein phosphorylation [GO:0006468]; regulation of cellular senescence [GO:2000772] cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829] ATP binding [GO:0005524]; manganese ion binding [GO:0030145]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96278 -2.5313 DLFAFQESPPR 0 0 0 0 9.40678 8.79941 0 0 0 0 0 0 0 9.29163 0 0 0 0 0 0 0 0 0 0 0 0 0 P51965 UB2E1_HUMAN Ubiquitin-conjugating enzyme E2 E1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme E1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme E1) (UbcH6) (Ubiquitin carrier protein E1) (Ubiquitin-protein ligase E1) UBE2E1 UBCH6 Homo sapiens (Human) histone H2B ubiquitination [GO:0033523]; ISG15-protein conjugation [GO:0032020]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151] ATP binding [GO:0005524]; ISG15 transferase activity [GO:0042296]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-protein transferase activity [GO:0004842] 0.80867 0.22692 ELADITLDPPPNCSAGPK 16.3788 16.3068 16.1814 15.4047 15.618 15.4799 11.1694 16.3787 16.5249 15.687 0 12.486 0 0 0 16.0045 0 0 12.8648 13.0972 0 12.5759 12.2782 12.3696 0 0 0 P52179 MYOM1_HUMAN Myomesin-1 (190 kDa connectin-associated protein) (190 kDa titin-associated protein) (Myomesin family member 1) MYOM1 Homo sapiens (Human) positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737] M band [GO:0031430]; striated muscle myosin thick filament [GO:0005863] identical protein binding [GO:0042802]; kinase binding [GO:0019900]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307] 0.88356 -0.32429 ASAMNVK 0 0 0 0 0 0 0 0 10.7747 0 0 0 0 0 0 0 10.3531 0 0 0 0 0 0 0 0 0 10.9023 P52209 6PGD_HUMAN "6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44)" PGD PGDH Homo sapiens (Human) "D-gluconate catabolic process [GO:0046177]; pentose biosynthetic process [GO:0019322]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]" cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634] NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616] 0 22.993 AGQAVDDFIEK 9.98042 9.20102 0 0 10.196 0 11.2186 10.7596 11.6182 11.3108 11.4101 10.5863 11.6287 10.7859 11.8738 10.6997 12.0092 11.1633 9.93895 9.72525 0 9.2141 10.3707 9.25911 12.2489 13.3392 12.7767 P52272 HNRPM_HUMAN Heterogeneous nuclear ribonucleoprotein M (hnRNP M) HNRNPM HNRPM NAGR1 Homo sapiens (Human) "alternative mRNA splicing, via spliceosome [GO:0000380]; mRNA splicing, via spliceosome [GO:0000398]" catalytic step 2 spliceosome [GO:0071013]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; spliceosomal complex [GO:0005681]; synapse [GO:0045202] mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723] 0 18.674 AAEVLNKHSLSGRPLKVK 0 0 0 0 0 0 0 0 8.37903 0 10.0833 8.71795 0 9.08012 0 0 0 0 9.11744 0 0 0 0 9.08279 0 11.839 11.7306 P52294 IMA5_HUMAN "Importin subunit alpha-5 (Karyopherin subunit alpha-1) (Nucleoprotein interactor 1) (NPI-1) (RAG cohort protein 2) (SRP1-beta) [Cleaved into: Importin subunit alpha-5, N-terminally processed]" KPNA1 RCH2 Homo sapiens (Human) NLS-bearing protein import into nucleus [GO:0006607]; postsynapse to nucleus signaling pathway [GO:0099527]; protein import into nucleus [GO:0006606]; regulation of apoptotic process [GO:0042981]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of DNA recombination [GO:0000018]; satellite cell activation involved in skeletal muscle regeneration [GO:0014901]; skeletal muscle satellite cell proliferation [GO:0014841] cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; NLS-dependent protein nuclear import complex [GO:0042564]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic density [GO:0014069] nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139] 0.9509 -1.4338 FVEFLKR 9.99209 0 0 0 0 8.58819 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.65794 0 0 0 0 0 0 P52333 JAK3_HUMAN Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK) JAK3 Homo sapiens (Human) adaptive immune response [GO:0002250]; B cell differentiation [GO:0030183]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; enzyme-linked receptor protein signaling pathway [GO:0007167]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; innate immune response [GO:0045087]; interleukin-15-mediated signaling pathway [GO:0035723]; interleukin-2-mediated signaling pathway [GO:0038110]; interleukin-4-mediated signaling pathway [GO:0035771]; interleukin-9-mediated signaling pathway [GO:0038113]; intracellular signal transduction [GO:0035556]; negative regulation of dendritic cell cytokine production [GO:0002731]; negative regulation of FasL production [GO:0045221]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of T cell activation [GO:0050868]; negative regulation of T-helper 1 cell differentiation [GO:0045626]; negative regulation of thymocyte apoptotic process [GO:0070244]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein phosphorylation [GO:0006468]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of apoptotic process [GO:0042981]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; regulation of T cell apoptotic process [GO:0070232]; response to interleukin-15 [GO:0070672]; response to interleukin-2 [GO:0070669]; response to interleukin-4 [GO:0070670]; response to interleukin-9 [GO:0071104]; T cell homeostasis [GO:0043029]; tyrosine phosphorylation of STAT protein [GO:0007260] cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endosome [GO:0005768]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; extrinsic component of plasma membrane [GO:0019897]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; cytokine receptor binding [GO:0005126]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713] 0.75887 0.30186 ALHSDFIVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0615 0 0 0 0 0 P52565 GDIR1_HUMAN Rho GDP-dissociation inhibitor 1 (Rho GDI 1) (Rho-GDI alpha) ARHGDIA GDIA1 Homo sapiens (Human) negative regulation of apoptotic process [GO:0043066]; regulation of protein localization [GO:0032880]; regulation of Rho protein signal transduction [GO:0035023]; regulation of synaptic vesicle cycle [GO:0098693]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526] cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; immunological synapse [GO:0001772]; membrane [GO:0016020]; nucleus [GO:0005634]; Schaffer collateral - CA1 synapse [GO:0098685] GTPase activator activity [GO:0005096]; Rho GDP-dissociation inhibitor activity [GO:0005094] 0 4.6905 AEEYEFLTPVEEAPK 0 0 0 0 0 0 0 0 0 0 9.00736 0 9.41661 9.5775 9.55209 9.83559 10.0362 10.091 0 0 0 0 0 0 9.6571 0 9.62383 P52566 GDIR2_HUMAN Rho GDP-dissociation inhibitor 2 (Rho GDI 2) (Ly-GDI) (Rho-GDI beta) ARHGDIB GDIA2 GDID4 RAP1GN1 Homo sapiens (Human) negative regulation of trophoblast cell migration [GO:1901164]; regulation of Rho protein signal transduction [GO:0035023]; Rho protein signal transduction [GO:0007266] cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020] GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; Rho GDP-dissociation inhibitor activity [GO:0005094]; small GTPase binding [GO:0031267] 0.93258 -1.2583 APNVVVTR 0 0 0 0 0 0 15.2989 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P52569 CTR2_HUMAN Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2) SLC7A2 ATRC2 CAT2 Homo sapiens (Human) amino acid import across plasma membrane [GO:0089718]; amino acid transport [GO:0006865]; L-alpha-amino acid transmembrane transport [GO:1902475]; L-amino acid transport [GO:0015807]; L-arginine import across plasma membrane [GO:0097638]; L-arginine transmembrane transport [GO:1903826]; L-ornithine transmembrane transport [GO:1903352]; transport across blood-brain barrier [GO:0150104] cell junction [GO:0030054]; plasma membrane [GO:0005886] amino acid transmembrane transporter activity [GO:0015171]; basic amino acid transmembrane transporter activity [GO:0015174]; L-amino acid transmembrane transporter activity [GO:0015179]; L-arginine transmembrane transporter activity [GO:0061459]; L-lysine transmembrane transporter activity [GO:0015189]; L-ornithine transmembrane transporter activity [GO:0000064] 0.81707 0.22072 SESQVTMLQR 9.97341 9.95248 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P52594 AGFG1_HUMAN Arf-GAP domain and FG repeat-containing protein 1 (HIV-1 Rev-binding protein) (Nucleoporin-like protein RIP) (Rev-interacting protein) (Rev/Rex activation domain-binding protein) AGFG1 HRB RAB RIP Homo sapiens (Human) acrosome assembly [GO:0001675]; intermediate filament organization [GO:0045109]; mRNA export from nucleus [GO:0006406]; spermatid nucleus differentiation [GO:0007289] cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nuclear pore [GO:0005643] DNA binding [GO:0003677]; GTPase activator activity [GO:0005096]; metal ion binding [GO:0046872]; RNA binding [GO:0003723] 0.92297 -1.103 EFLQEKYEK 0 0 0 0 0 0 0 8.94295 8.96162 0 0 0 0 0 0 0 9.28177 0 0 0 0 0 0 0 0 0 0 P52597 HNRPF_HUMAN "Heterogeneous nuclear ribonucleoprotein F (hnRNP F) (Nucleolin-like protein mcs94-1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein F, N-terminally processed]" HNRNPF HNRPF Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; regulation of RNA splicing [GO:0043484]; RNA processing [GO:0006396]" catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]; synapse [GO:0045202] RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727] 0 29.645 ALGKHKER 0 8.6773 8.65481 0 0 0 0 0 0 0 0 9.87857 0 0 0 11.2786 9.74546 0 0 0 0 0 9.57206 9.26852 10.3581 10.5824 10.0557 P52630 STAT2_HUMAN Signal transducer and activator of transcription 2 (p113) STAT2 Homo sapiens (Human) defense response [GO:0006952]; defense response to virus [GO:0051607]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of cell population proliferation [GO:0042127]; regulation of mitochondrial fission [GO:0090140]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription by RNA polymerase II [GO:0006357]; response to peptide hormone [GO:0043434]; type I interferon-mediated signaling pathway [GO:0060337] chromatin [GO:0000785]; cytosol [GO:0005829]; ISGF3 complex [GO:0070721]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; RNA polymerase II transcription regulator complex [GO:0090575] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; ubiquitin-like protein ligase binding [GO:0044389]" 0.95201 -1.4285 IPRDEAFGCYYQEKVNLQER 0 0 0 0 0 0 0 9.75702 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P52701 MSH6_HUMAN DNA mismatch repair protein Msh6 (hMSH6) (G/T mismatch-binding protein) (GTBP) (GTMBP) (MutS protein homolog 6) (MutS-alpha 160 kDa subunit) (p160) MSH6 GTBP Homo sapiens (Human) determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; isotype switching [GO:0045190]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; negative regulation of DNA recombination [GO:0045910]; positive regulation of helicase activity [GO:0051096]; response to UV [GO:0009411]; somatic hypermutation of immunoglobulin genes [GO:0016446]; somatic recombination of immunoglobulin gene segments [GO:0016447]; spermatogenesis [GO:0007283] chromatin [GO:0000785]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; MutSalpha complex [GO:0032301]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "ATP binding [GO:0005524]; ATP-dependent activity, acting on DNA [GO:0008094]; ATP-dependent DNA damage sensor activity [GO:0140664]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; enzyme binding [GO:0019899]; guanine/thymine mispair binding [GO:0032137]; methylated histone binding [GO:0035064]; mismatched DNA binding [GO:0030983]" 0.96171 -2.0431 ASARASREGGR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.86302 0 0 0 0 0 0 0 0 0 0 0 0 0 P52732 KIF11_HUMAN Kinesin-like protein KIF11 (Kinesin-like protein 1) (Kinesin-like spindle protein HKSP) (Kinesin-related motor protein Eg5) (Thyroid receptor-interacting protein 5) (TR-interacting protein 5) (TRIP-5) KIF11 EG5 KNSL1 TRIP5 Homo sapiens (Human) cell division [GO:0051301]; microtubule-based movement [GO:0007018]; mitotic cell cycle [GO:0000278]; mitotic centrosome separation [GO:0007100]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; regulation of mitotic centrosome separation [GO:0046602]; spindle elongation [GO:0051231]; spindle organization [GO:0007051] cytosol [GO:0005829]; kinesin complex [GO:0005871]; membrane [GO:0016020]; microtubule [GO:0005874]; mitotic spindle [GO:0072686]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle [GO:0005819]; spindle pole [GO:0000922] ATP binding [GO:0005524]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777]; plus-end-directed microtubule motor activity [GO:0008574]; protein kinase binding [GO:0019901] 0.96953 -3.1718 DIVNKMTFHSQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.70499 0 9.01929 0 10.6611 0 0 P52735 VAV2_HUMAN Guanine nucleotide exchange factor VAV2 (VAV-2) VAV2 Homo sapiens (Human) angiogenesis [GO:0001525]; cell migration [GO:0016477]; cellular response to xenobiotic stimulus [GO:0071466]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; lamellipodium assembly [GO:0030032]; platelet activation [GO:0030168]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886] epidermal growth factor receptor binding [GO:0005154]; guanyl-nucleotide exchange factor activity [GO:0005085]; metal ion binding [GO:0046872]; phosphotyrosine residue binding [GO:0001784] 0.96385 -2.2466 CGVGAHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.2077 0 10.2322 0 0 0 P52737 ZN136_HUMAN Zinc finger protein 136 ZNF136 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.81083 0.22471 EYQEYGEKPDTR 0 0 0 0 9.54926 0 0 0 0 0 0 0 0 0 0 8.87848 0 0 0 0 0 0 0 0 0 0 0 P52739 ZN131_HUMAN Zinc finger protein 131 ZNF131 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of cytokine production [GO:0001817]; regulation of immune system process [GO:0002682] intermediate filament cytoskeleton [GO:0045111]; nucleoplasm [GO:0005654] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]" 0.88437 -0.12728 KIHVCQYCEKQFDHFGHFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.3087 8.85823 0 0 0 0 0 0 0 10.3308 0 9.60489 P52740 ZN132_HUMAN Zinc finger protein 132 ZNF132 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.86625 0.074003 FHTGEIPHVCKECGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.39767 0 0 0 0 0 0 0 0 0 0 P52741 ZN134_HUMAN Zinc finger protein 134 ZNF134 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of cytokine production [GO:0001817]; regulation of immune system process [GO:0002682] nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.96334 -2.1951 DNLTQHKR 0 0 0 0 0 0 0 0 11.0486 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P52743 ZN137_HUMAN Putative zinc finger protein 137 (Zinc finger protein 137 pseudogene) ZNF137P ZNF137 Homo sapiens (Human) nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.94913 -1.3765 SHLIRHQRIHTGQK 15.648 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P52744 ZN138_HUMAN Zinc finger protein 138 ZNF138 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96161 -2.0755 ENFYKCEECGK 12.2387 0 12.0504 0 0 8.67292 12.9154 0 12.6908 13.025 9.42025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P52746 ZN142_HUMAN Zinc finger protein 142 ZNF142 KIAA0236 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.96792 -2.9253 FSCPTCPFSCQQER 10.2517 10.9742 10.7168 0 9.01528 8.72485 10.4148 0 0 0 0 0 0 9.12117 0 0 0 0 0 0 0 0 0 0 0 9.49887 0 P52756 RBM5_HUMAN RNA-binding protein 5 (Protein G15) (Putative tumor suppressor LUCA15) (RNA-binding motif protein 5) (Renal carcinoma antigen NY-REN-9) RBM5 H37 LUCA15 Homo sapiens (Human) "apoptotic process [GO:0006915]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of apoptotic process [GO:0043065]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA processing [GO:0006396]; spliceosomal complex assembly [GO:0000245]" nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681] DNA binding [GO:0003677]; metal ion binding [GO:0046872]; mRNA binding [GO:0003729]; RNA binding [GO:0003723] 0.95486 -1.5765 AAERREK 8.54377 13.4043 0 0 0 0 0 14.0973 0 0 10.4495 15.4457 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P52757 CHIO_HUMAN Beta-chimaerin (Beta-chimerin) (Rho GTPase-activating protein 3) CHN2 ARHGAP3 BCH Homo sapiens (Human) positive regulation of GTPase activity [GO:0043547]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] cytosol [GO:0005829]; membrane [GO:0016020]; synapse [GO:0045202] GTPase activator activity [GO:0005096]; metal ion binding [GO:0046872] 0.91363 -0.75944 FIDAAKISNADER 0 0 9.35255 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5535 0 P52788 SPSY_HUMAN Spermine synthase (SPMSY) (EC 2.5.1.22) (Spermidine aminopropyltransferase) SMS Homo sapiens (Human) methionine metabolic process [GO:0006555]; polyamine metabolic process [GO:0006595]; spermine biosynthetic process [GO:0006597] cytosol [GO:0005829]; extracellular exosome [GO:0070062] spermine synthase activity [GO:0016768] 0.55172 0.5617 AIMGSGK 0 0 0 0 9.49721 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.33706 9.16616 0 P52789 HXK2_HUMAN Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II) (Hexokinase-B) (Muscle form hexokinase) HK2 Homo sapiens (Human) apoptotic mitochondrial changes [GO:0008637]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular response to leukemia inhibitory factor [GO:1990830]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; intracellular glucose homeostasis [GO:0001678]; lactation [GO:0007595]; maintenance of protein location in mitochondrion [GO:0072656]; negative regulation of mitochondrial membrane permeability [GO:0035795]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; positive regulation of angiogenesis [GO:0045766]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; regulation of glucose import [GO:0046324]; response to hypoxia [GO:0001666]; response to ischemia [GO:0002931] centrosome [GO:0005813]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; sarcoplasmic reticulum [GO:0016529] ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396] 0.95974 -1.9472 EVCTVVARR 9.66073 0 0 0 0 0 0 0 0 0 0 0 8.82161 0 0 10.5718 0 0 0 0 0 0 0 10.002 0 0 0 P52798 EFNA4_HUMAN Ephrin-A4 (EPH-related receptor tyrosine kinase ligand 4) (LERK-4) EFNA4 EPLG4 LERK4 Homo sapiens (Human) axon guidance [GO:0007411]; cell-cell signaling [GO:0007267]; ephrin receptor signaling pathway [GO:0048013] extracellular region [GO:0005576]; plasma membrane [GO:0005886] ephrin receptor binding [GO:0046875]; transmembrane-ephrin receptor activity [GO:0005005] 0.94332 -1.3374 LQVSVCCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.5656 0 0 0 10.2372 0 0 0 0 P52799 EFNB2_HUMAN Ephrin-B2 (EPH-related receptor tyrosine kinase ligand 5) (LERK-5) (HTK ligand) (HTK-L) EFNB2 EPLG5 HTKL LERK5 Homo sapiens (Human) adherens junction organization [GO:0034332]; anatomical structure morphogenesis [GO:0009653]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; blood vessel morphogenesis [GO:0048514]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell-cell signaling [GO:0007267]; cellular response to lipopolysaccharide [GO:0071222]; ephrin receptor signaling pathway [GO:0048013]; keratinocyte proliferation [GO:0043616]; lymph vessel development [GO:0001945]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of neuron projection development [GO:0010977]; nephric duct morphogenesis [GO:0072178]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of neuron death [GO:1901216]; presynapse assembly [GO:0099054]; regulation of chemotaxis [GO:0050920]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; T cell costimulation [GO:0031295]; venous blood vessel morphogenesis [GO:0048845] adherens junction [GO:0005912]; dendrite [GO:0030425]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; presynaptic membrane [GO:0042734]; Schaffer collateral - CA1 synapse [GO:0098685] ephrin receptor binding [GO:0046875]; virus receptor activity [GO:0001618] 0.93054 -1.2469 DQADRCTIKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.7057 0 0 0 0 0 0 P52823 STC1_HUMAN Stanniocalcin-1 (STC-1) STC1 STC Homo sapiens (Human) bone development [GO:0060348]; cellular response to cAMP [GO:0071320]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to hypoxia [GO:0071456]; chondrocyte proliferation [GO:0035988]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; endothelial cell morphogenesis [GO:0001886]; growth plate cartilage axis specification [GO:0003421]; intracellular calcium ion homeostasis [GO:0006874]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell migration [GO:0030336]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of renal phosphate excretion [GO:1903403]; ossification [GO:0001503]; positive regulation of calcium ion import [GO:0090280]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of monoatomic anion transport [GO:0044070]; response to vitamin D [GO:0033280] apical plasma membrane [GO:0016324]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; nucleus [GO:0005634] hormone activity [GO:0005179]; identical protein binding [GO:0042802] 0.8013 0.23954 VAAQNSAEVVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3753 0 0 0 0 0 P52824 DGKQ_HUMAN Diacylglycerol kinase theta (DAG kinase theta) (DGKtheta) (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) DGKQ DAGK4 Homo sapiens (Human) cAMP-mediated signaling [GO:0019933]; diacylglycerol metabolic process [GO:0046339]; G protein-coupled receptor signaling pathway [GO:0007186]; glycerolipid metabolic process [GO:0046486]; intracellular signal transduction [GO:0035556]; lipid phosphorylation [GO:0046834]; negative regulation of gene expression [GO:0010629]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; peptidyl-serine phosphorylation [GO:0018105]; phosphatidic acid biosynthetic process [GO:0006654]; platelet activation [GO:0030168]; positive regulation of gene expression [GO:0010628]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; protein kinase C signaling [GO:0070528]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of cholesterol metabolic process [GO:0090181]; regulation of cortisol biosynthetic process [GO:2000064]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; regulation of gluconeogenesis [GO:0006111]; regulation of progesterone biosynthetic process [GO:2000182]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of TORC1 signaling [GO:1903432]; regulation of transcription by RNA polymerase II [GO:0006357]; response to ATP [GO:0033198]; response to cAMP [GO:0051591]; thrombin-activated receptor signaling pathway [GO:0070493] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endosome [GO:0005768]; glutamatergic synapse [GO:0098978]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; presynapse [GO:0098793]; vesicle membrane [GO:0012506] ATP binding [GO:0005524]; diacylglycerol kinase activity [GO:0004143]; DNA-binding transcription factor binding [GO:0140297]; kinase binding [GO:0019900]; metal ion binding [GO:0046872]; phospholipase binding [GO:0043274]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297] 0.92655 -1.2152 DLLCSFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.83924 8.6311 0 0 0 P52848 NDST1_HUMAN Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST-1) (N-heparan sulfate sulfotransferase 1) (N-HSST 1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) [Includes: Heparan sulfate N-deacetylase 1 (EC 3.5.1.-); Heparan sulfate N-sulfotransferase 1 (EC 2.8.2.8)] NDST1 HSST HSST1 Homo sapiens (Human) "aorta development [GO:0035904]; cardiac septum development [GO:0003279]; cell population proliferation [GO:0008283]; coronary vasculature development [GO:0060976]; embryonic neurocranium morphogenesis [GO:0048702]; embryonic viscerocranium morphogenesis [GO:0048703]; fibroblast growth factor receptor signaling pathway [GO:0008543]; forebrain development [GO:0030900]; heparan sulfate proteoglycan biosynthetic process, enzymatic modification [GO:0015015]; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; heparin biosynthetic process [GO:0030210]; inflammatory response [GO:0006954]; midbrain development [GO:0030901]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of smoothened signaling pathway [GO:0045880]; protein sulfation [GO:0006477]; respiratory gaseous exchange by respiratory system [GO:0007585]" Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; trans-Golgi network membrane [GO:0032588] [heparan sulfate]-glucosamine N-sulfotransferase activity [GO:0015016]; deacetylase activity [GO:0019213]; heparan sulfate N-deacetylase activity [GO:0102140]; N-acetylglucosamine deacetylase activity [GO:0050119] 0.92319 -1.1619 LLRTEPAK 0 11.8314 0 0 0 9.25394 0 0 0 0 0 10.7159 0 0 0 10.2755 0 0 8.39399 0 0 0 0 0 0 9.91931 0 P52888 THOP1_HUMAN Thimet oligopeptidase (EC 3.4.24.15) (Endopeptidase 24.15) (MP78) THOP1 Homo sapiens (Human) peptide metabolic process [GO:0006518]; protein polyubiquitination [GO:0000209]; proteolysis [GO:0006508] cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758] metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222] 0.92244 -1.0835 FKQEGVLNSK 0 0 0 0 0 0 0 0 0 0 0 0 10.3691 0 0 0 0 0 10.0039 0 10.0391 0 8.74305 0 0 0 0 P52895 AK1C2_HUMAN Aldo-keto reductase family 1 member C2 (EC 1.-.-.-) (EC 1.1.1.112) (EC 1.1.1.209) (EC 1.1.1.53) (EC 1.1.1.62) (EC 1.3.1.20) (3-alpha-HSD3) (Chlordecone reductase homolog HAKRD) (Dihydrodiol dehydrogenase 2) (DD-2) (DD2) (Dihydrodiol dehydrogenase/bile acid-binding protein) (DD/BABP) (Type III 3-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.357) AKR1C2 DDH2 Homo sapiens (Human) cellular response to jasmonic acid stimulus [GO:0071395]; cellular response to prostaglandin D stimulus [GO:0071799]; daunorubicin metabolic process [GO:0044597]; digestion [GO:0007586]; doxorubicin metabolic process [GO:0044598]; epithelial cell differentiation [GO:0030855]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein kinase B signaling [GO:0051897]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; steroid metabolic process [GO:0008202] cytosol [GO:0005829] "17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; androstan-3-alpha,17-beta-diol dehydrogenase activity [GO:0047044]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; estradiol 17-beta-dehydrogenase [NAD(P)] activity [GO:0004303]; indanol dehydrogenase activity [GO:0047718]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]" 0.0060241 2.5287 AIDGLNR 0 0 0 0 0 0 0 0 0 9.93469 0 0 0 0 8.77818 9.35008 9.52213 0 0 0 0 0 0 0 0 0 0 P52907 CAZA1_HUMAN F-actin-capping protein subunit alpha-1 (CapZ alpha-1) CAPZA1 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; barbed-end actin filament capping [GO:0051016]; cell junction assembly [GO:0034329]; protein-containing complex assembly [GO:0065003] actin cytoskeleton [GO:0015629]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; F-actin capping protein complex [GO:0008290]; WASH complex [GO:0071203] actin binding [GO:0003779]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296] 0.087452 1.2208 LLLNNDNLLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4799 0 0 0 0 0 0 0 0 0 0 0 0 P52945 PDX1_HUMAN Pancreas/duodenum homeobox protein 1 (PDX-1) (Glucose-sensitive factor) (GSF) (Insulin promoter factor 1) (IPF-1) (Insulin upstream factor 1) (IUF-1) (Islet/duodenum homeobox-1) (IDX-1) (Somatostatin-transactivating factor 1) (STF-1) PDX1 IPF1 STF1 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; animal organ regeneration [GO:0031100]; central nervous system development [GO:0007417]; digestive tract development [GO:0048565]; exocrine pancreas development [GO:0031017]; generation of precursor metabolites and energy [GO:0006091]; glucose mediated signaling pathway [GO:0010255]; glucose metabolic process [GO:0006006]; insulin secretion [GO:0030073]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; liver development [GO:0001889]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type B pancreatic cell apoptotic process [GO:2000675]; nitric oxide mediated signal transduction [GO:0007263]; positive regulation of cell death [GO:0010942]; positive regulation of DNA binding [GO:0043388]; positive regulation of insulin secretion [GO:0032024]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type B pancreatic cell proliferation [GO:1904692]; regulation of transcription by RNA polymerase II [GO:0006357]; response to alkaloid [GO:0043279]; response to chlorate [GO:0010157]; response to cytokine [GO:0034097]; response to fatty acid [GO:0070542]; response to glucocorticoid [GO:0051384]; response to iron(II) ion [GO:0010040]; response to leucine [GO:0043201]; response to nicotine [GO:0035094]; response to vitamin [GO:0033273]; response to wounding [GO:0009611]; response to xenobiotic stimulus [GO:0009410]; smoothened signaling pathway [GO:0007224]; stem cell differentiation [GO:0048863]; transcription by RNA polymerase II [GO:0006366]; transdifferentiation [GO:0060290]; type B pancreatic cell apoptotic process [GO:0097050]; type B pancreatic cell differentiation [GO:0003309]; type B pancreatic cell proliferation [GO:0044342] chromatin [GO:0000785]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; promoter-specific chromatin binding [GO:1990841]; protein-containing complex binding [GO:0044877]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96099 -2.0038 AQLLELEKEFLFNK 9.57609 0 0 0 0 0 9.27594 0 0 0 0 10.8934 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P52948 NUP98_HUMAN Nuclear pore complex protein Nup98-Nup96 (EC 3.4.21.-) [Cleaved into: Nuclear pore complex protein Nup98 (98 kDa nucleoporin) (Nucleoporin Nup98) (Nup98); Nuclear pore complex protein Nup96 (96 kDa nucleoporin) (Nucleoporin Nup96) (Nup96)] NUP98 ADAR2 Homo sapiens (Human) "mRNA transport [GO:0051028]; nuclear pore complex assembly [GO:0051292]; nuclear pore organization [GO:0006999]; nucleocytoplasmic transport [GO:0006913]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; RNA export from nucleus [GO:0006405]; telomere tethering at nuclear periphery [GO:0034398]" cytosol [GO:0005829]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear inclusion body [GO:0042405]; nuclear membrane [GO:0031965]; nuclear periphery [GO:0034399]; nuclear pore [GO:0005643]; nuclear pore cytoplasmic filaments [GO:0044614]; nuclear pore nuclear basket [GO:0044615]; nuclear pore outer ring [GO:0031080]; nucleoplasm [GO:0005654]; ribonucleoprotein complex [GO:1990904] mRNA binding [GO:0003729]; nuclear localization sequence binding [GO:0008139]; promoter-specific chromatin binding [GO:1990841]; RNA binding [GO:0003723]; serine-type peptidase activity [GO:0008236]; structural constituent of nuclear pore [GO:0017056]; transcription coactivator activity [GO:0003713] 0.94722 -1.3486 ELAVGSL 15.6511 0 0 0 0 0 10.0006 0 15.8561 0 10.0156 0 0 0 9.61314 0 10.7962 0 15.4849 0 15.6574 0 0 14.6563 0 15.8603 0 P52952 NKX25_HUMAN Homeobox protein Nkx-2.5 (Cardiac-specific homeobox) (Homeobox protein CSX) (Homeobox protein NK-2 homolog E) NKX2-5 CSX NKX2.5 NKX2E Homo sapiens (Human) adult heart development [GO:0007512]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in heart morphogenesis [GO:0003278]; atrial cardiac muscle cell development [GO:0055014]; atrial cardiac muscle tissue development [GO:0003228]; atrial septum morphogenesis [GO:0060413]; atrioventricular node cell development [GO:0060928]; atrioventricular node cell fate commitment [GO:0060929]; atrioventricular node development [GO:0003162]; bundle of His development [GO:0003166]; cardiac conduction system development [GO:0003161]; cardiac muscle cell development [GO:0055013]; cardiac muscle cell proliferation [GO:0060038]; cardiac muscle contraction [GO:0060048]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac ventricle formation [GO:0003211]; cell differentiation [GO:0030154]; embryonic heart tube development [GO:0035050]; embryonic heart tube left/right pattern formation [GO:0060971]; epithelial cell apoptotic process [GO:1904019]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation [GO:0050673]; heart looping [GO:0001947]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; hemopoiesis [GO:0030097]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of transcription by RNA polymerase II [GO:0000122]; outflow tract septum morphogenesis [GO:0003148]; pharyngeal system development [GO:0060037]; positive regulation of cardioblast differentiation [GO:0051891]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of gene expression [GO:0010628]; positive regulation of heart contraction [GO:0045823]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of sodium ion transport [GO:0010765]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; proepicardium development [GO:0003342]; pulmonary myocardium development [GO:0003350]; Purkinje myocyte differentiation [GO:0003168]; regulation of cardiac conduction [GO:1903779]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of cardiac muscle contraction [GO:0055117]; regulation of transcription by RNA polymerase II [GO:0006357]; right ventricular cardiac muscle tissue morphogenesis [GO:0003221]; septum secundum development [GO:0003285]; spleen development [GO:0048536]; thyroid gland development [GO:0030878]; transcription by RNA polymerase II [GO:0006366]; vasculogenesis [GO:0001570]; ventricular cardiac muscle cell development [GO:0055015]; ventricular cardiac myofibril assembly [GO:0055005]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription regulator complex [GO:0090575]; transcription regulator complex [GO:0005667] "chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]" 0.13811 1.0485 SLAAAGELSAR 9.64719 0 0 0 0 0 0 0 16.1514 16.6208 0 0 0 0 0 10.8045 0 14.938 0 12.8442 12.8105 13.021 0 0 0 0 0 P53004 BIEA_HUMAN Biliverdin reductase A (BVR A) (EC 1.3.1.24) (Biliverdin-IX alpha-reductase) BLVRA BLVR BVR Homo sapiens (Human) heme catabolic process [GO:0042167] cytosol [GO:0005829]; extracellular exosome [GO:0070062] biliberdin reductase NAD+ activity [GO:0106276]; biliverdin reductase (NAD(P)+) activity [GO:0004074]; biliverdin reductase (NADP+) activity [GO:0106277]; nucleotide binding [GO:0000166]; zinc ion binding [GO:0008270] 0.88483 -0.203 GSLLFTAGPLEEER 0 10.2172 9.88414 0 0 0 0 0 0 0 0 0 9.44669 0 9.65832 0 9.96193 0 0 0 0 0 0 0 0 0 0 P53007 TXTP_HUMAN "Tricarboxylate transport protein, mitochondrial (Citrate transport protein) (CTP) (Mitochondrial citrate carrier) (CIC) (Solute carrier family 25 member 1) (Tricarboxylate carrier protein)" SLC25A1 SLC20A3 Homo sapiens (Human) fatty-acyl-CoA biosynthetic process [GO:0046949]; gluconeogenesis [GO:0006094]; mitochondrial citrate transmembrane transport [GO:0006843] extracellular exosome [GO:0070062]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; nucleus [GO:0005634] antiporter activity [GO:0015297]; citrate secondary active transmembrane transporter activity [GO:0071913]; citrate transmembrane transporter activity [GO:0015137]; tricarboxylic acid transmembrane transporter activity [GO:0015142] 0.071006 1.2784 FIHDQTSPNPK 0 0 0 0 0 0 9.1607 0 0 0 0 0 0 0 8.47646 0 0 0 0 0 0 0 0 0 0 0 0 P53350 PLK1_HUMAN Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13) PLK1 PLK Homo sapiens (Human) centrosome cycle [GO:0007098]; establishment of mitotic spindle orientation [GO:0000132]; establishment of protein localization [GO:0045184]; female meiosis chromosome segregation [GO:0016321]; G2/M transition of mitotic cell cycle [GO:0000086]; homologous chromosome segregation [GO:0045143]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; mitotic chromosome condensation [GO:0007076]; mitotic cytokinesis [GO:0000281]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; mitotic nuclear membrane disassembly [GO:0007077]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint signaling [GO:0007094]; mitotic spindle organization [GO:0007052]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear membrane disassembly [GO:0051081]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of proteolysis [GO:0045862]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein localization to chromatin [GO:0071168]; protein localization to nuclear envelope [GO:0090435]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of anaphase-promoting complex-dependent catabolic process [GO:1905784]; regulation of cell cycle [GO:0051726]; regulation of cytokinesis [GO:0032465]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of mitotic spindle assembly [GO:1901673]; regulation of protein binding [GO:0043393]; regulation of protein localization to cell cortex [GO:1904776]; sister chromatid cohesion [GO:0007062]; synaptonemal complex disassembly [GO:0070194] centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; mitotic spindle pole [GO:0097431]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; outer kinetochore [GO:0000940]; spindle [GO:0005819]; spindle midzone [GO:0051233]; spindle pole [GO:0000922]; synaptonemal complex [GO:0000795] anaphase-promoting complex binding [GO:0010997]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.9691 -4.4375 APADPGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.73508 8.79695 0 0 0 0 0 0 0 P53355 DAPK1_HUMAN Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1) DAPK1 DAPK Homo sapiens (Human) apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to hydroperoxide [GO:0071447]; cellular response to type II interferon [GO:0071346]; defense response to tumor cell [GO:0002357]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intracellular signal transduction [GO:0035556]; negative regulation of apoptotic process [GO:0043066]; negative regulation of translation [GO:0017148]; positive regulation of apoptotic process [GO:0043065]; positive regulation of autophagic cell death [GO:1904094]; positive regulation of autophagy [GO:0010508]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of NMDA receptor activity [GO:2000310]; regulation of response to tumor cell [GO:0002834] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; DAPK1-calmodulin complex [GO:1990722]; glutamatergic synapse [GO:0098978]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; syntaxin-1 binding [GO:0017075] 0.96701 -2.8279 EHHEPVMIYQPRDFFR 0 0 0 0 0 0 0 8.65421 0 0 0 0 0 0 0 0 0 10.3329 0 0 0 0 9.94822 9.38616 0 0 10.468 P53384 NUBP1_HUMAN Cytosolic Fe-S cluster assembly factor NUBP1 (Nucleotide-binding protein 1) (NBP 1) NUBP1 NBP NBP1 Homo sapiens (Human) cell projection organization [GO:0030030]; centrosome localization [GO:0051642]; intracellular iron ion homeostasis [GO:0006879]; iron-sulfur cluster assembly [GO:0016226]; negative regulation of centrosome duplication [GO:0010826]; protein localization to cell cortex [GO:0072697]; regulation of cell growth [GO:0001558] centriole [GO:0005814]; cilium [GO:0005929]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886] "4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; ATP-dependent FeS chaperone activity [GO:0140663]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]" 0.9259 -1.2108 EINFCRKVK 0 0 0 0 0 0 0 0 0 0 0 0 10.145 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P53396 ACLY_HUMAN ATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase) (ACL) (Citrate cleavage enzyme) ACLY Homo sapiens (Human) acetyl-CoA biosynthetic process [GO:0006085]; cholesterol biosynthetic process [GO:0006695]; citrate metabolic process [GO:0006101]; coenzyme A metabolic process [GO:0015936]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099] azurophil granule lumen [GO:0035578]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654] ATP binding [GO:0005524]; ATP citrate synthase activity [GO:0003878]; metal ion binding [GO:0046872] 0 6.8246 AFDSGIIPMEFVNK 0 0 0 0 0 0 8.99135 0 9.28012 0 0 0 0 0 0 10.662 0 0 13.026 0 0 12.4157 12.3773 12.3652 13.9809 13.7272 13.578 P53420 CO4A4_HUMAN Collagen alpha-4(IV) chain COL4A4 Homo sapiens (Human) glomerular basement membrane development [GO:0032836] basement membrane [GO:0005604]; collagen type IV trimer [GO:0005587]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] extracellular matrix structural constituent [GO:0005201]; molecular adaptor activity [GO:0060090] 0.9676 -2.7414 GAKGDMVVSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2788 0 0 0 0 9.60348 0 0 0 0 0 P53582 MAP11_HUMAN Methionine aminopeptidase 1 (MAP 1) (MetAP 1) (EC 3.4.11.18) (Peptidase M 1) METAP1 KIAA0094 Homo sapiens (Human) N-terminal protein amino acid modification [GO:0031365]; peptidyl-methionine modification [GO:0018206]; platelet aggregation [GO:0070527]; protein initiator methionine removal involved in protein maturation [GO:0035551]; regulation of translation [GO:0006417] cytoplasm [GO:0005737]; cytosol [GO:0005829] aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]; metalloexopeptidase activity [GO:0008235] 0.80104 0.23953 LLSSEDIEGMR 0 0 0 0 0 0 9.5731 0 0 0 0 10.3518 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P53602 MVD1_HUMAN Diphosphomevalonate decarboxylase (EC 4.1.1.33) (Mevalonate (diphospho)decarboxylase) (MDDase) (Mevalonate pyrophosphate decarboxylase) MVD MPD Homo sapiens (Human) "cholesterol biosynthetic process [GO:0006695]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]; isoprenoid biosynthetic process [GO:0008299]; positive regulation of cell population proliferation [GO:0008284]" cytosol [GO:0005829] ATP binding [GO:0005524]; diphosphomevalonate decarboxylase activity [GO:0004163]; Hsp70 protein binding [GO:0030544]; protein homodimerization activity [GO:0042803] 0.91428 -0.77885 AESVVPARMAEMAR 0 0 0 0 0 0 0 0 0 11.6964 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P53609 PGTB1_HUMAN Geranylgeranyl transferase type-1 subunit beta (EC 2.5.1.59) (Geranylgeranyl transferase type I subunit beta) (GGTase-I-beta) (Type I protein geranyl-geranyltransferase subunit beta) PGGT1B Homo sapiens (Human) protein geranylgeranylation [GO:0018344] CAAX-protein geranylgeranyltransferase complex [GO:0005953] CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein geranylgeranyltransferase activity [GO:0004661]; zinc ion binding [GO:0008270] 0.88194 -0.31022 IFQYTNFEK 0 0 0 0 0 9.34651 0 0 0 0 0 0 0 0 10.1749 0 0 0 0 0 9.96288 0 0 0 0 0 0 P53618 COPB_HUMAN Coatomer subunit beta (Beta-coat protein) (Beta-COP) COPB1 COPB MSTP026 Homo sapiens (Human) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886] COPI vesicle coat [GO:0030126]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; ficolin-1-rich granule membrane [GO:0101003]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle [GO:0005798]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; tertiary granule membrane [GO:0070821]; transport vesicle [GO:0030133] structural molecule activity [GO:0005198] 0.73741 0.32669 LLHEMILVCDAYR 0 0 0 0 0 0 0 0 0 0 0 9.7874 0 0 0 0 0 0 9.35224 0 0 0 9.98371 0 0 10.8258 0 P53621 COPA_HUMAN Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEP-COP) (HEPCOP) [Cleaved into: Xenin (Xenopsin-related peptide); Proxenin] COPA Homo sapiens (Human) "endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; pancreatic juice secretion [GO:0030157]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]" COPI vesicle coat [GO:0030126]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; growth cone [GO:0030426]; membrane [GO:0016020]; transport vesicle [GO:0030133] hormone activity [GO:0005179]; structural molecule activity [GO:0005198] 0.0060423 2.5538 DVAVMQLR 0 0 0 0 0 0 0 10.8391 0 0 0 0 11.5013 12.1964 0 12.053 0 11.9186 8.69978 10.3285 8.9183 0 9.39333 10.4075 11.1179 11.5346 10.3227 P53634 CATC_HUMAN Dipeptidyl peptidase 1 (EC 3.4.14.1) (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain (Dipeptidyl peptidase I heavy chain); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)] CTSC CPPI Homo sapiens (Human) aging [GO:0007568]; immune response [GO:0006955]; negative regulation of myelination [GO:0031642]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of proteolysis involved in protein catabolic process [GO:1903052]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; response to organic substance [GO:0010033]; T cell mediated cytotoxicity [GO:0001913] azurophil granule lumen [GO:0035578]; centrosome [GO:0005813]; collagen-containing extracellular matrix [GO:0062023]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; membrane [GO:0016020]; nucleoplasm [GO:0005654] chloride ion binding [GO:0031404]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; peptidase activator activity involved in apoptotic process [GO:0016505]; phosphatase binding [GO:0019902]; protein self-association [GO:0043621]; protein-folding chaperone binding [GO:0051087]; serine-type endopeptidase activity [GO:0004252] 0.89707 -0.67099 GIYHHTGLR 0 0 0 0 0 0 0 0 0 0 8.25035 11.2242 0 0 0 0 0 0 0 9.00377 0 0 0 0 0 0 0 P53667 LIMK1_HUMAN LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1) LIMK1 LIMK Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; axon extension [GO:0048675]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; nervous system development [GO:0007399]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of axon extension [GO:0045773]; positive regulation of stress fiber assembly [GO:0051496]; protein phosphorylation [GO:0006468]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]; stress fiber assembly [GO:0043149] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; male germ cell nucleus [GO:0001673]; membrane [GO:0016020]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleus [GO:0005634] ATP binding [GO:0005524]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.89914 -0.65443 LTLLCCTWR 0 0 0 0 0 0 0 0 0 0 9.94021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P53672 CRBA2_HUMAN Beta-crystallin A2 (Beta-A2 crystallin) CRYBA2 Homo sapiens (Human) lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601] identical protein binding [GO:0042802]; structural constituent of eye lens [GO:0005212] 0.84908 0.16313 VTLFEGDNFQGCK 0 0 0 0 0 0 0 0 0 0 0 10.3366 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P53673 CRBA4_HUMAN Beta-crystallin A4 (Beta-A4 crystallin) CRYBA4 Homo sapiens (Human) camera-type eye development [GO:0043010]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601] identical protein binding [GO:0042802]; structural constituent of eye lens [GO:0005212] 0.88388 -0.050262 LTIFEQENFLGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0707 0 0 0 10.141 0 0 0 9.47509 0 0 0 P53674 CRBB1_HUMAN Beta-crystallin B1 (Beta-B1 crystallin) CRYBB1 Homo sapiens (Human) lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601] structural constituent of eye lens [GO:0005212] 0.86432 0.084335 LMSFRPIKMDAQEHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3365 0 0 0 P53675 CLH2_HUMAN Clathrin heavy chain 2 (Clathrin heavy chain on chromosome 22) (CLH-22) CLTCL1 CLH22 CLTCL CLTD Homo sapiens (Human) "anatomical structure morphogenesis [GO:0009653]; intracellular protein transport [GO:0006886]; mitotic cell cycle [GO:0000278]; positive regulation of glucose import [GO:0046326]; receptor-mediated endocytosis [GO:0006898]; retrograde transport, endosome to Golgi [GO:0042147]" clathrin coat of trans-Golgi network vesicle [GO:0030130]; clathrin complex [GO:0071439]; clathrin-coated endocytic vesicle [GO:0045334]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; coated vesicle [GO:0030135]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; late endosome [GO:0005770]; membrane [GO:0016020]; sorting endosome [GO:0097443]; spindle [GO:0005819]; trans-Golgi network [GO:0005802] clathrin light chain binding [GO:0032051]; structural molecule activity [GO:0005198] 0.47236 0.62874 AYEFAER 0 0 0 0 0 0 0 0 0 11.8498 0 0 0 0 9.06051 8.89788 0 0 0 0 0 0 0 0 0 0 0 P53677 AP3M2_HUMAN AP-3 complex subunit mu-2 (Adaptor-related protein complex 3 subunit mu-2) (Clathrin assembly protein assembly protein complex 3 mu-2 medium chain) (Clathrin coat assembly protein AP47 homolog 2) (Clathrin coat-associated protein AP47 homolog 2) (Golgi adaptor AP-1 47 kDa protein homolog 2) (HA1 47 kDa subunit homolog 2) (Mu3B-adaptin) (P47B) AP3M2 Homo sapiens (Human) "anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; clathrin-coated vesicle cargo loading, AP-3-mediated [GO:0035654]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; intracellular transport [GO:0046907]; synaptic vesicle coating [GO:0016183]; synaptic vesicle recycling [GO:0036465]" AP-3 adaptor complex [GO:0030123]; AP-type membrane coat adaptor complex [GO:0030119]; axon cytoplasm [GO:1904115]; clathrin adaptor complex [GO:0030131]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; early endosome [GO:0005769]; Golgi apparatus [GO:0005794]; presynapse [GO:0098793] 0.80364 0.23766 LLDDVSFHPCVR 0 0 0 0 0 0 0 0 0 12.1239 0 0 0 0 0 8.51621 0 0 0 0 0 0 0 0 0 0 0 P53701 CCHL_HUMAN Holocytochrome c-type synthase (EC 4.4.1.17) (Cytochrome c-type heme lyase) HCCS CCHL Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cytochrome c-heme linkage [GO:0018063] cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] heme binding [GO:0020037]; holocytochrome-c synthase activity [GO:0004408]; metal ion binding [GO:0046872] 0.9138 -0.76079 HDWIINRCGTEVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.60859 0 0 0 0 0 0 0 0 P53708 ITA8_HUMAN Integrin alpha-8 [Cleaved into: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain] ITGA8 Homo sapiens (Human) brain development [GO:0007420]; cell adhesion mediated by integrin [GO:0033627]; cell projection organization [GO:0030030]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; establishment of protein localization [GO:0045184]; extracellular matrix organization [GO:0030198]; inner ear morphogenesis [GO:0042472]; integrin-mediated signaling pathway [GO:0007229]; kidney development [GO:0001822]; memory [GO:0007613]; mesodermal cell differentiation [GO:0048333]; metanephros development [GO:0001656]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; smooth muscle cell differentiation [GO:0051145]; smooth muscle tissue development [GO:0048745]; substrate adhesion-dependent cell spreading [GO:0034446]; transforming growth factor beta receptor signaling pathway [GO:0007179] apical part of cell [GO:0045177]; cell surface [GO:0009986]; dendritic spine membrane [GO:0032591]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integrin alpha8-beta1 complex [GO:0034678]; integrin complex [GO:0008305]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839] integrin binding [GO:0005178]; metal ion binding [GO:0046872] 0.60467 0.4382 DVHVVEFHR 0 0 11.9154 0 0 0 0 9.59182 9.39738 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P53794 SC5A3_HUMAN Sodium/myo-inositol cotransporter (Na(+)/myo-inositol cotransporter) (Sodium/myo-inositol transporter 1) (SMIT1) (Solute carrier family 5 member 3) SLC5A3 Homo sapiens (Human) fucose transmembrane transport [GO:0015756]; glucose transmembrane transport [GO:1904659]; inositol metabolic process [GO:0006020]; myo-inositol import across plasma membrane [GO:1904679]; myo-inositol transport [GO:0015798]; pentose transmembrane transport [GO:0015750]; peripheral nervous system development [GO:0007422]; polyol transmembrane transport [GO:0015791]; positive regulation of catalytic activity [GO:0043085]; positive regulation of protein localization to membrane [GO:1905477]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; regulation of respiratory gaseous exchange [GO:0043576]; regulation of transporter activity [GO:0032409]; transport across blood-brain barrier [GO:0150104] apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076] fucose transmembrane transporter activity [GO:0015150]; glucose:sodium symporter activity [GO:0005412]; myo-inositol transmembrane transporter activity [GO:0005365]; myo-inositol:sodium symporter activity [GO:0005367]; pentose transmembrane transporter activity [GO:0015146]; polyol transmembrane transporter activity [GO:0015166]; potassium channel regulator activity [GO:0015459]; transmembrane transporter binding [GO:0044325] 0.72238 0.35976 KETDDGGRYWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0853 0 0 0 0 0 0 0 0 0 0 0 P53801 PTTG_HUMAN Pituitary tumor-transforming gene 1 protein-interacting protein (Pituitary tumor-transforming gene protein-binding factor) (PBF) (PTTG-binding factor) PTTG1IP C21orf1 C21orf3 Homo sapiens (Human) "negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; positive regulation of protein ubiquitination [GO:0031398]; protein import into nucleus [GO:0006606]" cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] p53 binding [GO:0002039] 0.84933 0.1653 APGVARGPTPYWRLR 12.7671 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4114 0 12.4282 0 0 0 0 0 0 0 0 0 0 P53804 TTC3_HUMAN E3 ubiquitin-protein ligase TTC3 (EC 2.3.2.27) (Protein DCRR1) (RING finger protein 105) (RING-type E3 ubiquitin transferase TTC3) (TPR repeat protein D) (Tetratricopeptide repeat protein 3) (TPR repeat protein 3) TTC3 DCRR1 RNF105 TPRD Homo sapiens (Human) protein K48-linked ubiquitination [GO:0070936]; ubiquitin-dependent protein catabolic process [GO:0006511] cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] metal ion binding [GO:0046872]; ubiquitin-protein transferase activity [GO:0004842] 0.96988 -5.2703 IGCKIENK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.78329 9.27705 0 0 0 P53805 RCAN1_HUMAN Calcipressin-1 (Adapt78) (Down syndrome critical region protein 1) (Myocyte-enriched calcineurin-interacting protein 1) (MCIP1) (Regulator of calcineurin 1) RCAN1 ADAPT78 CSP1 DSC1 DSCR1 Homo sapiens (Human) calcineurin-NFAT signaling cascade [GO:0033173]; calcium-mediated signaling [GO:0019722]; locomotion involved in locomotory behavior [GO:0031987]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; regulation of phosphoprotein phosphatase activity [GO:0043666]; response to ischemia [GO:0002931]; response to oxidative stress [GO:0006979]; short-term memory [GO:0007614]; skeletal muscle fiber development [GO:0048741] cytoplasm [GO:0005737]; nucleus [GO:0005634] calcium-dependent protein serine/threonine phosphatase regulator activity [GO:0008597]; identical protein binding [GO:0042802]; nucleic acid binding [GO:0003676] 0.9298 -1.2402 FESLFRTYDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.94181 P53814 SMTN_HUMAN Smoothelin SMTN SMSMO Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; muscle organ development [GO:0007517]; smooth muscle contraction [GO:0006939] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; filamentous actin [GO:0031941]; microtubule organizing center [GO:0005815] actin binding [GO:0003779]; structural constituent of muscle [GO:0008307] 0.89636 -0.54043 AGSLAALEKRQAEK 0 0 0 0 0 0 9.1606 0 0 9.29085 9.95574 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6692 0 0 P53990 IST1_HUMAN IST1 homolog (hIST1) (Charged multivesicular body protein 8) (CHMP8) (Putative MAPK-activating protein PM28) IST1 KIAA0174 Homo sapiens (Human) abscission [GO:0009838]; cell division [GO:0051301]; collateral sprouting [GO:0048668]; cytoskeleton-dependent cytokinesis [GO:0061640]; ESCRT III complex disassembly [GO:1904903]; establishment of protein localization [GO:0045184]; multivesicular body assembly [GO:0036258]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of proteolysis [GO:0045862]; protein localization [GO:0008104]; protein transport [GO:0015031]; viral capsid secondary envelopment [GO:0046745]; viral release from host cell [GO:0019076] azurophil granule lumen [GO:0035578]; centrosome [GO:0005813]; cytosol [GO:0005829]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Flemming body [GO:0090543]; intracellular membrane-bounded organelle [GO:0043231]; midbody [GO:0030496]; nuclear envelope [GO:0005635] cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; MIT domain binding [GO:0090541]; protein domain specific binding [GO:0019904]; protein-containing complex binding [GO:0044877] 0.61333 0.42054 IVADQLCAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.09355 0 0 0 0 0 0 9.5705 0 0 9.53349 0 0 P53992 SC24C_HUMAN Protein transport protein Sec24C (SEC24-related protein C) SEC24C KIAA0079 Homo sapiens (Human) COPII-coated vesicle cargo loading [GO:0090110]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; in utero embryonic development [GO:0001701]; intracellular protein transport [GO:0006886] COPII vesicle coat [GO:0030127]; cytosol [GO:0005829]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507] SNARE binding [GO:0000149]; zinc ion binding [GO:0008270] 0.89841 -0.6832 GQVPPLVTTNFLVK 0 0 0 0 0 9.93764 0 0 0 0 0 0 0 0 0 0 0 0 9.81102 9.84304 9.82464 0 0 0 11.6406 11.506 0 P54098 DPOG1_HUMAN DNA polymerase subunit gamma-1 (EC 2.7.7.7) (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha) POLG MDP1 POLG1 POLGA Homo sapiens (Human) "base-excision repair, gap-filling [GO:0006287]; DNA metabolic process [GO:0006259]; DNA-templated DNA replication [GO:0006261]; mitochondrial DNA replication [GO:0006264]" gamma DNA polymerase complex [GO:0005760]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991] 3'-5' exonuclease activity [GO:0008408]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; protease binding [GO:0002020] 0.96086 -2.0151 AAVPGQPLALTARGGPK 0 0 0 0 0 0 0 0 0 0 0 0 9.65889 0 0 10.7999 0 0 0 0 0 9.17632 0 0 0 0 0 P54132 BLM_HUMAN "RecQ-like DNA helicase BLM (EC 3.6.4.12) (Bloom syndrome protein) (DNA helicase, RecQ-like type 2) (RecQ2) (RecQ protein-like 3)" BLM RECQ2 RECQL3 Homo sapiens (Human) cellular response to camptothecin [GO:0072757]; cellular response to hydroxyurea [GO:0072711]; cellular response to ionizing radiation [GO:0071479]; DNA damage response [GO:0006974]; DNA double-strand break processing [GO:0000729]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; G-quadruplex DNA unwinding [GO:0044806]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of cell division [GO:0051782]; negative regulation of DNA recombination [GO:0045910]; positive regulation of DNA-templated transcription [GO:0045893]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of DNA-templated DNA replication [GO:0090329]; replication fork processing [GO:0031297]; resolution of recombination intermediates [GO:0071139]; response to X-ray [GO:0010165]; t-circle formation [GO:0090656]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomeric D-loop disassembly [GO:0061820] chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lateral element [GO:0000800]; nuclear chromosome [GO:0000228]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; RecQ family helicase-topoisomerase III complex [GO:0031422]; replication fork [GO:0005657] "3'-5' DNA helicase activity [GO:0043138]; 8-hydroxy-2'-deoxyguanosine DNA binding [GO:1905773]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent activity, acting on DNA [GO:0008094]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; DNA/DNA annealing activity [GO:1990814]; forked DNA-dependent helicase activity [GO:0061749]; four-way junction DNA binding [GO:0000400]; four-way junction helicase activity [GO:0009378]; G-quadruplex DNA binding [GO:0051880]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; molecular function activator activity [GO:0140677]; p53 binding [GO:0002039]; protein homodimerization activity [GO:0042803]; single-stranded DNA binding [GO:0003697]; telomeric D-loop binding [GO:0061821]; telomeric G-quadruplex DNA binding [GO:0061849]; Y-form DNA binding [GO:0000403]; zinc ion binding [GO:0008270]" 0.97 -5.3595 DLLSKPEK 0 8.08942 0 0 0 0 0 0 0 0 0 0 9.21189 0 9.40986 0 0 0 0 0 9.94163 0 0 0 0 0 10.3038 P54136 SYRC_HUMAN "Arginine--tRNA ligase, cytoplasmic (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS)" RARS1 RARS Homo sapiens (Human) arginyl-tRNA aminoacylation [GO:0006420]; tRNA aminoacylation for protein translation [GO:0006418] aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] arginine binding [GO:0034618]; arginine-tRNA ligase activity [GO:0004814]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; tRNA binding [GO:0000049] 0.007732 2.0351 FDTEEEFKKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5301 10.8488 10.0861 P54257 HAP1_HUMAN Huntingtin-associated protein 1 (HAP-1) (Neuroan 1) HAP1 HAP2 HLP1 Homo sapiens (Human) "anterograde axonal transport [GO:0008089]; anterograde axonal transport of mitochondrion [GO:0098957]; autophagy [GO:0006914]; brain development [GO:0007420]; cell projection organization [GO:0030030]; cerebellum development [GO:0021549]; chemical synaptic transmission [GO:0007268]; exocytosis [GO:0006887]; hypothalamus cell differentiation [GO:0021979]; mitochondrion distribution [GO:0048311]; negative regulation of amyloid-beta formation [GO:1902430]; neurogenesis [GO:0022008]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; positive regulation of neurogenesis [GO:0050769]; positive regulation of neurotrophin production [GO:0032901]; positive regulation of non-motile cilium assembly [GO:1902857]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; protein localization [GO:0008104]; protein targeting [GO:0006605]; regulation of exocytosis [GO:0017157]; regulation of organelle transport along microtubule [GO:1902513]; retrograde axonal transport [GO:0008090]; vesicle transport along microtubule [GO:0047496]" actin cytoskeleton [GO:0015629]; autophagosome [GO:0005776]; axon cytoplasm [GO:1904115]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; growth cone [GO:0030426]; inclusion body [GO:0016234]; lysosome [GO:0005764]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; synaptic vesicle [GO:0008021] brain-derived neurotrophic factor binding [GO:0048403]; myosin binding [GO:0017022]; signaling receptor binding [GO:0005102]; transmembrane transporter binding [GO:0044325] 0.92063 -1.1436 YDFRYSEDREQVR 0 0 0 0 0 9.04456 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P54259 ATN1_HUMAN Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein) ATN1 D12S755E DRPLA Homo sapiens (Human) cell killing [GO:0001906]; cell migration [GO:0016477]; central nervous system development [GO:0007417]; determination of adult lifespan [GO:0008340]; maintenance of cell polarity [GO:0030011]; male gonad development [GO:0008584]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron apoptotic process [GO:0051402]; post-embryonic development [GO:0009791]; response to food [GO:0032094]; spermatogenesis [GO:0007283] anchoring junction [GO:0070161]; cytoplasm [GO:0005737]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] protein domain specific binding [GO:0019904]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714] 0.93273 -1.2657 DIDQDNR 0 0 0 0 0 0 0 9.69745 0 0 0 0 10.6315 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P54277 PMS1_HUMAN PMS1 protein homolog 1 (DNA mismatch repair protein PMS1) PMS1 PMSL1 Homo sapiens (Human) mismatch repair [GO:0006298]; response to xenobiotic stimulus [GO:0009410] MutLalpha complex [GO:0032389]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent DNA damage sensor activity [GO:0140664]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; mismatched DNA binding [GO:0030983] 0.52612 0.58576 EVYECRPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.36012 0 0 0 0 P54278 PMS2_HUMAN Mismatch repair endonuclease PMS2 (EC 3.1.-.-) (DNA mismatch repair protein PMS2) (PMS1 protein homolog 2) PMS2 PMSL2 Homo sapiens (Human) mismatch repair [GO:0006298]; response to xenobiotic stimulus [GO:0009410]; somatic hypermutation of immunoglobulin genes [GO:0016446] cytosol [GO:0005829]; MutLalpha complex [GO:0032389]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent DNA damage sensor activity [GO:0140664]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; single base insertion or deletion binding [GO:0032138] 0.87035 0.039308 GSQEHVDSQEKAPK 0 0 9.00756 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.05772 0 0 P54289 CA2D1_HUMAN Voltage-dependent calcium channel subunit alpha-2/delta-1 (Voltage-gated calcium channel subunit alpha-2/delta-1) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-1; Voltage-dependent calcium channel subunit delta-1] CACNA2D1 CACNL2A CCHL2A MHS3 Homo sapiens (Human) calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transmembrane transport via high voltage-gated calcium channel [GO:0061577]; calcium ion transport [GO:0006816]; calcium ion transport into cytosol [GO:0060402]; cardiac muscle cell action potential involved in contraction [GO:0086002]; cellular response to amyloid-beta [GO:1904646]; membrane depolarization during bundle of His cell action potential [GO:0086048]; positive regulation of high voltage-gated calcium channel activity [GO:1901843]; positive regulation of muscle contraction [GO:0045933]; regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1902514]; regulation of calcium ion transport [GO:0051924]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of membrane repolarization during action potential [GO:0098903]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307] extracellular exosome [GO:0070062]; L-type voltage-gated calcium channel complex [GO:1990454]; neuronal dense core vesicle [GO:0098992]; plasma membrane [GO:0005886]; sarcoplasmic reticulum [GO:0016529]; voltage-gated calcium channel complex [GO:0005891] metal ion binding [GO:0046872]; voltage-gated calcium channel activity [GO:0005245] 0.62483 0.41218 MQEDLVTLAK 0 0 0 0 0 0 0 0 0 0 0 0 10.2051 0 0 9.86436 0 0 0 0 0 0 0 0 0 10.9564 0 P54296 MYOM2_HUMAN Myomesin-2 (165 kDa connectin-associated protein) (165 kDa titin-associated protein) (M-protein) (Myomesin family member 2) MYOM2 Homo sapiens (Human) muscle contraction [GO:0006936]; sarcomere organization [GO:0045214] M band [GO:0031430]; mitochondrion [GO:0005739]; myosin filament [GO:0032982] kinase binding [GO:0019900]; structural constituent of muscle [GO:0008307] 0.9616 -2.5798 EVSDSEIHR 0 0 0 9.07911 0 10.7336 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.54971 0 0 0 0 0 P54315 LIPR1_HUMAN Inactive pancreatic lipase-related protein 1 (PL-RP1) PNLIPRP1 PLRP1 Homo sapiens (Human) lipid catabolic process [GO:0016042] extracellular region [GO:0005576] calcium ion binding [GO:0005509]; triglyceride lipase activity [GO:0004806] 0.90819 -0.74255 VKFLWNNNVINPTLPK 0 0 0 0 0 0 0 0 8.63016 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P54577 SYYC_HUMAN "Tyrosine--tRNA ligase, cytoplasmic (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) [Cleaved into: Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed]" YARS1 YARS Homo sapiens (Human) apoptotic process [GO:0006915]; response to starvation [GO:0042594]; tyrosyl-tRNA aminoacylation [GO:0006437] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nuclear body [GO:0016604]; nucleus [GO:0005634] ATP binding [GO:0005524]; interleukin-8 receptor binding [GO:0005153]; resveratrol binding [GO:1905594]; RNA binding [GO:0003723]; small molecule binding [GO:0036094]; tRNA binding [GO:0000049]; tyrosine-tRNA ligase activity [GO:0004831] 0.96344 -2.114 FIKGTDYQLSK 8.78633 0 0 0 0 0 0 8.95852 0 0 0 0 0 9.72206 0 0 0 0 0 0 0 0 0 0 11.0166 9.92019 0 P54646 AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) PRKAA2 AMPK AMPK2 Homo sapiens (Human) autophagy [GO:0006914]; cellular response to calcium ion [GO:0071277]; cellular response to glucose starvation [GO:0042149]; cellular response to glucose stimulus [GO:0071333]; cellular response to nutrient levels [GO:0031669]; cellular response to oxidative stress [GO:0034599]; cellular response to prostaglandin E stimulus [GO:0071380]; cellular response to xenobiotic stimulus [GO:0071466]; cholesterol biosynthetic process [GO:0006695]; energy homeostasis [GO:0097009]; fatty acid biosynthetic process [GO:0006633]; fatty acid homeostasis [GO:0055089]; glucose homeostasis [GO:0042593]; intracellular signal transduction [GO:0035556]; lipid biosynthetic process [GO:0008610]; lipid droplet disassembly [GO:1905691]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; negative regulation of hepatocyte apoptotic process [GO:1903944]; negative regulation of TOR signaling [GO:0032007]; negative regulation of tubulin deacetylation [GO:1904428]; positive regulation of autophagy [GO:0010508]; positive regulation of glycolytic process [GO:0045821]; positive regulation of macroautophagy [GO:0016239]; positive regulation of peptidyl-lysine acetylation [GO:2000758]; positive regulation of protein localization [GO:1903829]; protein localization to lipid droplet [GO:1990044]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of macroautophagy [GO:0016241]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of stress granule assembly [GO:0062028]; response to muscle activity [GO:0014850]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055] axon [GO:0030424]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; neuronal cell body [GO:0043025]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634] [acetyl-CoA carboxylase] kinase activity [GO:0050405]; [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity [GO:0047322]; AMP-activated protein kinase activity [GO:0004679]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; histone H2BS36 kinase activity [GO:0140823]; metal ion binding [GO:0046872]; molecular function activator activity [GO:0140677]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712] 0.92454 -1.0655 DIREHEWFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.55855 0 P54652 HSP72_HUMAN Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2) HSPA2 Homo sapiens (Human) chaperone cofactor-dependent protein refolding [GO:0051085]; male meiosis I [GO:0007141]; male meiotic nuclear division [GO:0007140]; negative regulation of inclusion body assembly [GO:0090084]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein phosphorylation [GO:0001934]; protein refolding [GO:0042026]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; synaptonemal complex disassembly [GO:0070194] blood microparticle [GO:0072562]; CatSper complex [GO:0036128]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; male germ cell nucleus [GO:0001673]; meiotic spindle [GO:0072687]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synaptonemal complex [GO:0000795] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; glycolipid binding [GO:0051861]; heat shock protein binding [GO:0031072]; protein folding chaperone [GO:0044183]; protein-folding chaperone binding [GO:0051087]; tau protein binding [GO:0048156]; unfolded protein binding [GO:0051082] 0.95101 -1.4337 ARFEELNADLFR 11.1476 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P54707 AT12A_HUMAN Potassium-transporting ATPase alpha chain 2 (HK alpha 2) (Non-gastric H(+)/K(+) ATPase subunit alpha) (EC 7.2.2.19) (Non-gastric Na(+)/K(+) ATPase subunit alpha) (EC 7.2.2.13) (Proton pump) (Sodium pump) ATP12A ATP1AL1 Homo sapiens (Human) intracellular potassium ion homeostasis [GO:0030007]; intracellular sodium ion homeostasis [GO:0006883]; potassium ion import across plasma membrane [GO:1990573]; proton transmembrane transport [GO:1902600]; regulation of pH [GO:0006885]; sodium ion export across plasma membrane [GO:0036376] actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; potassium:proton exchanging ATPase complex [GO:0005889] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; metal ion binding [GO:0046872]; P-type potassium:proton transporter activity [GO:0008900]; P-type sodium:potassium-exchanging transporter activity [GO:0005391] 0.96406 -2.2529 AAELLAR 0 9.85308 0 0 0 9.42167 0 11.3882 0 0 10.4438 0 0 9.4483 0 10.3699 0 0 0 10.008 0 0 0 0 9.33266 0 0 P54725 RD23A_HUMAN UV excision repair protein RAD23 homolog A (HR23A) (hHR23A) RAD23A Homo sapiens (Human) nucleotide-excision repair [GO:0006289]; positive regulation of cell cycle [GO:0045787]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of viral genome replication [GO:0045070]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434] cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991] damaged DNA binding [GO:0003684]; kinase binding [GO:0019900]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; single-stranded DNA binding [GO:0003697]; ubiquitin binding [GO:0043130]; ubiquitin-specific protease binding [GO:1990381] 0.94024 -1.3106 DAFPVAGQK 0 9.96622 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P54727 RD23B_HUMAN UV excision repair protein RAD23 homolog B (HR23B) (hHR23B) (XP-C repair-complementing complex 58 kDa protein) (p58) RAD23B Homo sapiens (Human) cellular response to interleukin-7 [GO:0098761]; embryonic organ development [GO:0048568]; nucleotide-excision repair [GO:0006289]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; spermatogenesis [GO:0007283] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; XPC complex [GO:0071942] damaged DNA binding [GO:0003684]; DNA damage sensor activity [GO:0140612]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; single-stranded DNA binding [GO:0003697]; ubiquitin binding [GO:0043130] 0.0081081 2.0855 DAFPVAGQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2312 0 0 0 0 0 0 0 0 0 0 10.2467 P54753 EPHB3_HUMAN Ephrin type-B receptor 3 (EC 2.7.10.1) (EPH-like tyrosine kinase 2) (EPH-like kinase 2) (Embryonic kinase 2) (EK2) (hEK2) (Tyrosine-protein kinase TYRO6) EPHB3 ETK2 HEK2 TYRO6 Homo sapiens (Human) angiogenesis [GO:0001525]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; cell migration [GO:0016477]; central nervous system projection neuron axonogenesis [GO:0021952]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; digestive tract morphogenesis [GO:0048546]; ephrin receptor signaling pathway [GO:0048013]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of axonogenesis [GO:0050770]; regulation of cell-cell adhesion [GO:0022407]; regulation of GTPase activity [GO:0043087]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; substrate adhesion-dependent cell spreading [GO:0034446]; thymus development [GO:0048538]; urogenital system development [GO:0001655] cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular region [GO:0005576]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; ephrin receptor activity [GO:0005003]; transmembrane-ephrin receptor activity [GO:0005005] 0.92051 -0.91595 LQMNQTLPVQV 0 0 0 0 0 0 12.279 0 0 0 0 10.4018 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P54756 EPHA5_HUMAN Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology kinase 1) (EHK-1) (EPH-like kinase 7) (EK7) (hEK7) EPHA5 BSK EHK1 HEK7 TYRO4 Homo sapiens (Human) axon guidance [GO:0007411]; cAMP-mediated signaling [GO:0019933]; ephrin receptor signaling pathway [GO:0048013]; hippocampus development [GO:0021766]; neuron development [GO:0048666]; positive regulation of CREB transcription factor activity [GO:0032793]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of GTPase activity [GO:0043087]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178] axon [GO:0030424]; dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791] ATP binding [GO:0005524]; ephrin receptor activity [GO:0005003]; GPI-linked ephrin receptor activity [GO:0005004]; transmembrane-ephrin receptor activity [GO:0005005] 0.19939 0.92012 KDVSYYIACKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8065 10.0013 0 0 0 9.07502 0 0 0 0 P54760 EPHB4_HUMAN Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11) EPHB4 HTK MYK1 TYRO11 Homo sapiens (Human) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; ephrin receptor signaling pathway [GO:0048013]; heart morphogenesis [GO:0003007]; positive regulation of kinase activity [GO:0033674]; protein autophosphorylation [GO:0046777] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] ATP binding [GO:0005524]; ephrin receptor activity [GO:0005003]; transmembrane receptor protein tyrosine kinase activity [GO:0004714] 0.66327 0.39432 GIASGMR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.63815 10.3308 0 9.3872 9.54564 0 0 0 9.5435 0 0 P54762 EPHB1_HUMAN Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase 2) (EPH-like kinase 6) (EK6) (hEK6) (Neuronally-expressed EPH-related tyrosine kinase) (NET) (Tyrosine-protein kinase receptor EPH-2) EPHB1 ELK EPHT2 HEK6 NET Homo sapiens (Human) angiogenesis [GO:0001525]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; cell chemotaxis [GO:0060326]; cell-substrate adhesion [GO:0031589]; central nervous system projection neuron axonogenesis [GO:0021952]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; ephrin receptor signaling pathway [GO:0048013]; establishment of cell polarity [GO:0030010]; hindbrain tangential cell migration [GO:0021934]; immunological synapse formation [GO:0001771]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of satellite cell differentiation [GO:1902725]; negative regulation of skeletal muscle satellite cell proliferation [GO:1902723]; neural precursor cell proliferation [GO:0061351]; neurogenesis [GO:0022008]; optic nerve morphogenesis [GO:0021631]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; retinal ganglion cell axon guidance [GO:0031290]; skeletal muscle satellite cell activation [GO:0014719] axon [GO:0030424]; cytosol [GO:0005829]; dendrite [GO:0030425]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; filopodium tip [GO:0032433]; glutamatergic synapse [GO:0098978]; membrane raft [GO:0045121]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; protein-containing complex binding [GO:0044877]; transmembrane-ephrin receptor activity [GO:0005005] 0.95571 -1.5452 AGYSEKQR 0 0 0 0 0 0 9.07125 9.21704 0 0 0 0 0 0 10.7399 0 0 0 9.25677 0 0 0 0 0 0 0 0 P54764 EPHA4_HUMAN Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK) EPHA4 HEK8 SEK TYRO1 Homo sapiens (Human) adherens junction organization [GO:0034332]; adult walking behavior [GO:0007628]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cellular response to amyloid-beta [GO:1904646]; cochlea development [GO:0090102]; corticospinal tract morphogenesis [GO:0021957]; ephrin receptor signaling pathway [GO:0048013]; fasciculation of motor neuron axon [GO:0097156]; fasciculation of sensory neuron axon [GO:0097155]; glial cell migration [GO:0008347]; motor neuron axon guidance [GO:0008045]; negative regulation of axon regeneration [GO:0048681]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular response to hypoxia [GO:1900038]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of neuron projection development [GO:0010977]; negative regulation of proteolysis involved in protein catabolic process [GO:1903051]; negative regulation of translation [GO:0017148]; nephric duct morphogenesis [GO:0072178]; neuron projection fasciculation [GO:0106030]; neuron projection guidance [GO:0097485]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of Rho guanyl-nucleotide exchange factor activity [GO:2001108]; protein autophosphorylation [GO:0046777]; protein stabilization [GO:0050821]; regulation of astrocyte differentiation [GO:0048710]; regulation of axonogenesis [GO:0050770]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of GTPase activity [GO:0043087]; regulation of modification of synaptic structure [GO:1905244]; regulation of synapse pruning [GO:1905806]; synapse pruning [GO:0098883] adherens junction [GO:0005912]; axon [GO:0030424]; axon terminus [GO:0043679]; axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; filopodium [GO:0030175]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; mitochondrial outer membrane [GO:0005741]; neuromuscular junction [GO:0031594]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; presynaptic membrane [GO:0042734]; Schaffer collateral - CA1 synapse [GO:0098685] amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; DH domain binding [GO:0097161]; ephrin receptor binding [GO:0046875]; GPI-linked ephrin receptor activity [GO:0005004]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; PH domain binding [GO:0042731]; protein kinase activity [GO:0004672]; protein tyrosine kinase activity [GO:0004713]; protein tyrosine kinase binding [GO:1990782]; translation regulator activity [GO:0045182]; transmembrane-ephrin receptor activity [GO:0005005] 0.95142 -1.4389 EGAQRVYIEIK 0 0 0 0 14.777 0 0 0 0 0 0 8.87157 15.3696 15.3396 9.34061 11.9691 12.375 12.3897 0 9.2299 0 0 0 0 10.0961 0 0 P54792 DVLP1_HUMAN Putative segment polarity protein dishevelled homolog DVL1P1 (DSH homolog 1-like) (Segment polarity protein dishevelled homolog DVL-1-like) (Dishevelled-1-like) DVL1P1 DVL DVL1 DVL1L1 Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; planar cell polarity pathway involved in neural tube closure [GO:0090179] cytosol [GO:0005829] frizzled binding [GO:0005109] 0.95586 -1.5484 ELAAVPPELTGSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.19069 0 0 0 P54803 GALC_HUMAN Galactocerebrosidase (GALCERase) (EC 3.2.1.46) (Galactocerebroside beta-galactosidase) (Galactosylceramidase) (Galactosylceramide beta-galactosidase) GALC Homo sapiens (Human) galactosylceramide catabolic process [GO:0006683]; glycosphingolipid metabolic process [GO:0006687]; myelination [GO:0042552] lysosomal lumen [GO:0043202]; lysosome [GO:0005764] galactosylceramidase activity [GO:0004336] 0.61656 0.41794 SQPFPSTYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.57268 0 0 0 0 0 0 0 0 0 0 0 P54819 KAD2_HUMAN "Adenylate kinase 2, mitochondrial (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase) [Cleaved into: Adenylate kinase 2, mitochondrial, N-terminally processed]" AK2 ADK2 Homo sapiens (Human) ADP biosynthetic process [GO:0006172]; AMP metabolic process [GO:0046033]; ATP metabolic process [GO:0046034]; nucleobase-containing small molecule interconversion [GO:0015949]; phosphorylation [GO:0016310] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; sperm mitochondrial sheath [GO:0097226] adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524] 0.88138 -0.30492 APSVPAAEPEYPK 0 0 0 0 0 0 0 0 8.92905 0 0 0 0 0 0 0 0 0 0 0 0 9.45327 0 0 10.1457 9.28983 10.1058 P54826 GAS1_HUMAN Growth arrest-specific protein 1 (GAS-1) GAS1 Homo sapiens (Human) cell cycle [GO:0007049]; cell fate commitment [GO:0045165]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; developmental growth [GO:0048589]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of protein processing [GO:0010955]; regulation of apoptotic process [GO:0042981]; regulation of ER to Golgi vesicle-mediated transport [GO:0060628]; regulation of smoothened signaling pathway [GO:0008589] membrane [GO:0016020]; plasma membrane [GO:0005886] 0.67088 0.39371 SSGGGGR 0 0 0 0 9.31499 0 0 0 0 0 9.09413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P54840 GYS2_HUMAN "Glycogen [starch] synthase, liver (EC 2.4.1.11)" GYS2 Homo sapiens (Human) generation of precursor metabolites and energy [GO:0006091]; glycogen biosynthetic process [GO:0005978]; response to glucose [GO:0009749] cell cortex [GO:0005938]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; ectoplasm [GO:0043265] "glycogen (starch) synthase activity [GO:0004373]; glycogen synthase activity, transferring glucose-1-phosphate [GO:0061547]" 0.92256 -1.0833 FLYGFCK 0 0 9.73767 0 0 0 0 0 0 0 0 0 0 0 0 0 8.92736 0 0 0 0 0 0 0 0 0 0 P54845 NRL_HUMAN Neural retina-specific leucine zipper protein (NRL) NRL D14S46E Homo sapiens (Human) positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; response to stimulus [GO:0050896]; retinal rod cell development [GO:0046548]; visual perception [GO:0007601] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; leucine zipper domain binding [GO:0043522]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.68819 0.38672 ELNRQLR 0 0 0 0 0 0 0 0 0 0 0 11.3317 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P54886 P5CS_HUMAN Delta-1-pyrroline-5-carboxylate synthase (P5CS) (Aldehyde dehydrogenase family 18 member A1) [Includes: Glutamate 5-kinase (GK) (EC 2.7.2.11) (Gamma-glutamyl kinase); Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)] ALDH18A1 GSAS P5CS PYCS Homo sapiens (Human) citrulline biosynthetic process [GO:0019240]; glutamate metabolic process [GO:0006536]; L-proline biosynthetic process [GO:0055129]; ornithine biosynthetic process [GO:0006592]; phosphorylation [GO:0016310]; proline biosynthetic process [GO:0006561] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; glutamate 5-kinase activity [GO:0004349]; glutamate-5-semialdehyde dehydrogenase activity [GO:0004350]; identical protein binding [GO:0042802]; RNA binding [GO:0003723] 0.020455 1.6003 GPVGLEGLLTTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.10392 0 0 0 0 0 10.8455 9.99393 8.61611 P54920 SNAA_HUMAN Alpha-soluble NSF attachment protein (SNAP-alpha) (N-ethylmaleimide-sensitive factor attachment protein alpha) NAPA SNAPA Homo sapiens (Human) "apical protein localization [GO:0045176]; brain development [GO:0007420]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]; neuron differentiation [GO:0030182]; regulation of synaptic vesicle priming [GO:0010807]; SNARE complex disassembly [GO:0035494]; synaptic transmission, glutamatergic [GO:0035249]; synaptic vesicle priming [GO:0016082]" cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; synaptobrevin 2-SNAP-25-syntaxin-1a complex [GO:0070044] protein-containing complex binding [GO:0044877]; SNARE binding [GO:0000149]; soluble NSF attachment protein activity [GO:0005483]; syntaxin binding [GO:0019905] 0.42246 0.66555 GEESNSSANK 0 0 0 8.47978 0 0 0 12.5695 0 12.9576 0 13.3571 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0362 0 P55008 AIF1_HUMAN Allograft inflammatory factor 1 (AIF-1) (Ionized calcium-binding adapter molecule 1) (Protein G1) AIF1 G1 IBA1 Homo sapiens (Human) "actin crosslink formation [GO:0051764]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; cellular response to extracellular stimulus [GO:0031668]; cellular response to hormone stimulus [GO:0032870]; cellular response to hydroperoxide [GO:0071447]; cellular response to morphine [GO:0071315]; cellular response to oxidative stress [GO:0034599]; cellular response to type II interferon [GO:0071346]; cerebellum development [GO:0021549]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of smooth muscle cell proliferation [GO:0048662]; parallel actin filament bundle assembly [GO:0030046]; phagocytosis, engulfment [GO:0006911]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemotaxis [GO:0050921]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of muscle hyperplasia [GO:0014739]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell chemotaxis [GO:0071673]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell migration [GO:2000406]; positive regulation of T cell proliferation [GO:0042102]; Rac protein signal transduction [GO:0016601]; regulation of gene expression [GO:0010468]; response to axon injury [GO:0048678]; response to electrical stimulus [GO:0051602]; response to glucocorticoid [GO:0051384]; ruffle assembly [GO:0097178]" actin filament [GO:0005884]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glial cell projection [GO:0097386]; lamellipodium [GO:0030027]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; phagocytic cup [GO:0001891]; ruffle [GO:0001726]; ruffle membrane [GO:0032587] actin filament binding [GO:0051015]; calcium ion binding [GO:0005509] 0.95252 -1.4644 EKYMEFDLNGNGDIDIMSLKR 0 0 0 0 10.7934 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P55010 IF5_HUMAN Eukaryotic translation initiation factor 5 (eIF-5) EIF5 Homo sapiens (Human) formation of cytoplasmic translation initiation complex [GO:0001732]; formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446] cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; synapse [GO:0045202] cadherin binding [GO:0045296]; eukaryotic initiation factor eIF2 binding [GO:0071074]; GDP-dissociation inhibitor activity [GO:0005092]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; translation initiation factor activity [GO:0003743] 0.95924 -1.8334 QTIGNSCKACGYR 0 0 0 0 0 0 0 0 0 0 0 9.817 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P55011 S12A2_HUMAN Solute carrier family 12 member 2 (Basolateral Na-K-Cl symporter) (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2) SLC12A2 NKCC1 Homo sapiens (Human) aging [GO:0007568]; ammonium transmembrane transport [GO:0072488]; cell volume homeostasis [GO:0006884]; cellular response to chemokine [GO:1990869]; cellular response to potassium ion [GO:0035865]; chloride ion homeostasis [GO:0055064]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; hyperosmotic response [GO:0006972]; inorganic anion import across plasma membrane [GO:0098658]; inorganic cation import across plasma membrane [GO:0098659]; intracellular chloride ion homeostasis [GO:0030644]; intracellular potassium ion homeostasis [GO:0030007]; intracellular sodium ion homeostasis [GO:0006883]; maintenance of blood-brain barrier [GO:0035633]; monoatomic ion transport [GO:0006811]; negative regulation of vascular wound healing [GO:0061044]; positive regulation of aspartate secretion [GO:1904450]; positive regulation of cell volume [GO:0045795]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; regulation of matrix metallopeptidase secretion [GO:1904464]; regulation of spontaneous synaptic transmission [GO:0150003]; sodium ion homeostasis [GO:0055078]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]; T cell chemotaxis [GO:0010818]; transepithelial ammonium transport [GO:0070634]; transepithelial chloride transport [GO:0030321]; transport across blood-brain barrier [GO:0150104] apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell body [GO:0044297]; cell body membrane [GO:0044298]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cell projection membrane [GO:0031253]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular vesicle [GO:1903561]; lateral plasma membrane [GO:0016328]; membrane [GO:0016020]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886] ammonium transmembrane transporter activity [GO:0008519]; chloride:monoatomic cation symporter activity [GO:0015377]; Hsp90 protein binding [GO:0051879]; metal ion transmembrane transporter activity [GO:0046873]; potassium ion transmembrane transporter activity [GO:0015079]; protein kinase binding [GO:0019901]; protein-folding chaperone binding [GO:0051087]; sodium:potassium:chloride symporter activity [GO:0008511] 0 34.114 AAAAAAAAAAAAAAAGAGAGAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.765 9.58308 9.05813 11.2636 11.7966 11.5324 12.8036 12.8771 11.9661 P55039 DRG2_HUMAN Developmentally-regulated GTP-binding protein 2 (DRG-2) (Translation factor GTPase DRG2) (TRAFAC GTPase DRG2) (EC 3.6.5.-) DRG2 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; RNA binding [GO:0003723] 0.88902 -0.4518 EIARTQKNK 0 0 0 0 0 0 0 0 0 0 0 8.76212 0 0 0 0 0 0 0 0 0 0 0 9.84015 0 0 0 P55040 GEM_HUMAN GTP-binding protein GEM (GTP-binding mitogen-induced T-cell protein) (RAS-like protein KIR) GEM KIR Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; chromosome organization [GO:0051276]; immune response [GO:0006955]; metaphase plate congression [GO:0051310]; mitotic cell cycle [GO:0000278]; negative regulation of high voltage-gated calcium channel activity [GO:1901842]; signal transduction [GO:0007165] cytoplasmic side of plasma membrane [GO:0009898]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; spindle midzone [GO:0051233] calcium channel regulator activity [GO:0005246]; calmodulin binding [GO:0005516]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287] 0.95199 -1.4521 EPHQYSHRNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.265 0 P55060 XPO2_HUMAN Exportin-2 (Exp2) (Cellular apoptosis susceptibility protein) (Chromosome segregation 1-like protein) (Importin-alpha re-exporter) CSE1L CAS XPO2 Homo sapiens (Human) protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] nuclear export signal receptor activity [GO:0005049]; small GTPase binding [GO:0031267] 0.0096386 1.7769 ADGIKYIMIFRNQVPK 0 0 11.2503 0 0 0 12.4221 0 9.08308 11.7749 9.18391 0 10.2394 11.3853 11.3343 0 12.049 11.8648 12.9095 12.6517 12.3727 11.7831 0 11.0293 0 13.1414 12.9641 P55061 BI1_HUMAN Bax inhibitor 1 (BI-1) (Testis-enhanced gene transcript protein) (Transmembrane BAX inhibitor motif-containing protein 6) TMBIM6 BI1 TEGT Homo sapiens (Human) autophagy [GO:0006914]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; negative regulation of apoptotic process [GO:0043066]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of calcium ion transport into cytosol [GO:0010523]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of endoribonuclease activity [GO:0060702]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of immunoglobulin production [GO:0002638]; negative regulation of protein binding [GO:0032091]; negative regulation of RNA splicing [GO:0033119]; negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990441]; neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0036483]; response to L-glutamate [GO:1902065] cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; plasma membrane [GO:0005886] endoribonuclease inhibitor activity [GO:0060698]; enzyme binding [GO:0019899]; ubiquitin protein ligase binding [GO:0031625] 0.914 -0.79682 KINFDALLK 10.1925 0 0 0 9.97284 0 0 0 11.6424 0 11.3002 0 0 11.7683 0 0 0 0 0 0 10.7607 0 0 10.1289 0 0 0 P55072 TERA_HUMAN Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP) VCP Homo sapiens (Human) "activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to heat [GO:0034605]; DNA damage response [GO:0006974]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; interstrand cross-link repair [GO:0036297]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; negative regulation of protein localization to chromatin [GO:0120186]; negative regulation of smoothened signaling pathway [GO:0045879]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; positive regulation of protein-containing complex assembly [GO:0031334]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; protein-DNA covalent cross-linking repair [GO:0106300]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of protein localization to chromatin [GO:1905634]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]" ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730] ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-dependent protein binding [GO:0140036]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381] 0 23.466 AIGVKPPR 10.9629 9.88507 9.47123 0 0 0 9.66787 9.88917 10.2752 10.7467 10.7853 11.0715 11.5421 11.2102 11.1387 12.089 11.1447 11.4864 10.0627 11.4848 9.70319 0 11.0394 0 11.0241 11.5845 11.4709 P55081 MFAP1_HUMAN Microfibrillar-associated protein 1 (Spliceosome B complex protein MFAP1) MFAP1 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]" centrosome [GO:0005813]; microfibril [GO:0001527]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type precatalytic spliceosome [GO:0071005]; U2-type spliceosomal complex [GO:0005684] RNA binding [GO:0003723] 0.96985 -4.693 IVEEETK 11.0345 0 0 0 0 0 0 0 0 0 0 10.1579 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P55084 ECHB_HUMAN "Trifunctional enzyme subunit beta, mitochondrial (TP-beta) [Includes: 3-ketoacyl-CoA thiolase (EC 2.3.1.155) (EC 2.3.1.16) (Acetyl-CoA acyltransferase) (Beta-ketothiolase)]" HADHB MSTP029 Homo sapiens (Human) cellular response to lipopolysaccharide [GO:0071222]; fatty acid beta-oxidation [GO:0006635]; gene expression [GO:0010467] endoplasmic reticulum [GO:0005783]; mitochondrial envelope [GO:0005740]; mitochondrial fatty acid beta-oxidation multienzyme complex [GO:0016507]; mitochondrial inner membrane [GO:0005743]; mitochondrial nucleoid [GO:0042645]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739] 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; acetyl-CoA C-acyltransferase activity [GO:0003988]; acetyl-CoA C-myristoyltransferase activity [GO:0050633]; enoyl-CoA hydratase activity [GO:0004300]; lncRNA binding [GO:0106222]; RNA binding [GO:0003723] 0 3.306 EAALGAGFSDK 0 0 0 0 0 0 9.26864 8.83829 8.95852 9.30469 0 0 0 0 0 0 0 0 0 8.07334 8.30797 9.55767 9.88554 0 9.57622 10.2327 12.06 P55089 UCN1_HUMAN Urocortin UCN Homo sapiens (Human) "activation of protein kinase A activity [GO:0034199]; aerobic respiration [GO:0009060]; associative learning [GO:0008306]; drinking behavior [GO:0042756]; female pregnancy [GO:0007565]; G protein-coupled receptor signaling pathway [GO:0007186]; gastric emptying [GO:0035483]; inflammatory response [GO:0006954]; negative regulation of apoptotic process [GO:0043066]; negative regulation of appetite [GO:0032099]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell size [GO:0045792]; negative regulation of feeding behavior [GO:2000252]; negative regulation of gastric acid secretion [GO:0060455]; negative regulation of gene expression [GO:0010629]; negative regulation of hormone secretion [GO:0046888]; negative regulation of necrotic cell death [GO:0060547]; negative regulation of neuron death [GO:1901215]; neuron projection development [GO:0031175]; neuropeptide signaling pathway [GO:0007218]; pancreatic juice secretion [GO:0030157]; positive regulation of behavioral fear response [GO:2000987]; positive regulation of calcium ion import [GO:0090280]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of cell growth [GO:0030307]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of corticotropin secretion [GO:0051461]; positive regulation of DNA replication [GO:0045740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of vascular permeability [GO:0043117]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to auditory stimulus [GO:0010996]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to oxidative stress [GO:0006979]; response to pain [GO:0048265]; sensory perception of sound [GO:0007605]; social behavior [GO:0035176]; startle response [GO:0001964]; vasodilation [GO:0042311]" axon terminus [GO:0043679]; dendrite [GO:0030425]; extracellular region [GO:0005576]; perikaryon [GO:0043204]; varicosity [GO:0043196] corticotropin-releasing hormone receptor 1 binding [GO:0051430]; corticotropin-releasing hormone receptor 2 binding [GO:0051431]; histone deacetylase inhibitor activity [GO:0046811]; neuropeptide hormone activity [GO:0005184] 0.96393 -2.22 IIFDSVGK 0 0 0 0 0 0 0 0 9.15773 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P55107 GDF10_HUMAN Growth/differentiation factor 10 (GDF-10) (Bone morphogenetic protein 3B) (BMP-3B) (Bone-inducing protein) (BIP) GDF10 BMP3B Homo sapiens (Human) BMP signaling pathway [GO:0030509]; cerebellum development [GO:0021549]; fat cell differentiation [GO:0045444]; negative regulation of osteoblast differentiation [GO:0045668]; osteoblast differentiation [GO:0001649]; ovulation cycle [GO:0042698]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; regulation of ossification [GO:0030278]; skeletal system development [GO:0001501]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179] collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615] cytokine activity [GO:0005125]; growth factor activity [GO:0008083] 0.94733 -1.3486 KGQEVFMAASQVLDFDEKTMQK 0 9.04598 0 0 9.49727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.38573 9.56522 0 0 0 0 0 P55157 MTP_HUMAN Microsomal triglyceride transfer protein large subunit MTTP MTP Homo sapiens (Human) cholesterol homeostasis [GO:0042632]; chylomicron assembly [GO:0034378]; circadian rhythm [GO:0007623]; establishment of localization in cell [GO:0051649]; lipid metabolic process [GO:0006629]; lipoprotein metabolic process [GO:0042157]; lipoprotein transport [GO:0042953]; low-density lipoprotein particle remodeling [GO:0034374]; phospholipid transport [GO:0015914]; plasma lipoprotein particle assembly [GO:0034377]; protein lipidation [GO:0006497]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; triglyceride metabolic process [GO:0006641]; triglyceride transport [GO:0034197]; very-low-density lipoprotein particle assembly [GO:0034379] basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; Golgi apparatus [GO:0005794]; microvillus membrane [GO:0031528]; receptor complex [GO:0043235]; rough endoplasmic reticulum [GO:0005791]; vesicle [GO:0031982] apolipoprotein binding [GO:0034185]; ceramide 1-phosphate transfer activity [GO:1902388]; cholesterol transfer activity [GO:0120020]; lipid binding [GO:0008289]; lipid transporter activity [GO:0005319]; phosphatidylcholine transfer activity [GO:0120019]; phosphatidylethanolamine transfer activity [GO:1904121]; phospholipid transfer activity [GO:0120014]; phospholipid transporter activity [GO:0005548]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; triglyceride transfer activity [GO:0140344] 0.95981 -1.9086 LCQNEGCKLKAVVEAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.77946 0 0 0 0 0 P55160 NCKPL_HUMAN Nck-associated protein 1-like (Hematopoietic protein 1) (Membrane-associated protein HEM-1) NCKAP1L HEM1 Homo sapiens (Human) "actin polymerization-dependent cell motility [GO:0070358]; B cell homeostasis [GO:0001782]; B cell receptor signaling pathway [GO:0050853]; cell migration [GO:0016477]; cell morphogenesis [GO:0000902]; cell projection assembly [GO:0030031]; chemotaxis [GO:0006935]; cortical actin cytoskeleton organization [GO:0030866]; erythrocyte development [GO:0048821]; erythrocyte homeostasis [GO:0034101]; maintenance of cell polarity [GO:0030011]; myeloid cell homeostasis [GO:0002262]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cytotoxic T cell degranulation [GO:0043318]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; neuron projection morphogenesis [GO:0048812]; neutrophil chemotaxis [GO:0030593]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043372]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gamma-delta T cell differentiation [GO:0045588]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of lymphocyte differentiation [GO:0045621]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of neutrophil migration [GO:1902624]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of phosphorylation [GO:0042327]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of TORC2 signaling [GO:1904515]; protein-containing complex assembly [GO:0065003]; response to xenobiotic stimulus [GO:0009410]; T cell homeostasis [GO:0043029]" cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; membrane [GO:0016020]; plasma membrane [GO:0005886]; SCAR complex [GO:0031209]; secretory granule membrane [GO:0030667] GTPase activator activity [GO:0005096]; protein kinase activator activity [GO:0030295]; protein-containing complex binding [GO:0044877]; TORC2 complex binding [GO:1904841] 0.74235 0.32124 SIVTNMDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9588 0 0 0 0 P55196 AFAD_HUMAN Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6) (Afadin adherens junction formation factor) AFDN AF6 MLLT4 Homo sapiens (Human) bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell signaling [GO:0007267]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of protein localization to plasma membrane [GO:0061951]; negative regulation of cell migration [GO:0030336]; pore complex assembly [GO:0046931]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of gene expression [GO:0010628]; regulation of protein localization [GO:0032880]; signal transduction [GO:0007165] adherens junction [GO:0005912]; cell junction [GO:0030054]; cell-cell contact zone [GO:0044291]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; pore complex [GO:0046930]; tight junction [GO:0070160] actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; small GTPase binding [GO:0031267] 0.96918 -3.996 ELQPQQQPR 0 0 0 0 0 0 0 0 0 0 0 0 9.27069 0 0 9.48812 9.44946 0 0 0 9.0677 0 0 0 0 10.8374 0 P55198 AF17_HUMAN Protein AF-17 (ALL1-fused gene from chromosome 17 protein) MLLT6 AF17 Homo sapiens (Human) chromatin organization [GO:0006325]; negative regulation of urine volume [GO:0035811]; positive regulation of sodium ion transport [GO:0010765]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; renal potassium excretion [GO:0036359]; renal sodium excretion [GO:0035812]; renal water absorption [GO:0070295] nucleus [GO:0005634] histone binding [GO:0042393]; metal ion binding [GO:0046872]; nucleosome binding [GO:0031491] 0.92267 -1.1024 DPISHSGGMLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.29119 0 0 0 0 P55201 BRPF1_HUMAN Peregrin (Bromodomain and PHD finger-containing protein 1) (Protein Br140) BRPF1 BR140 Homo sapiens (Human) chromatin remodeling [GO:0006338]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355]; regulation of hemopoiesis [GO:1903706]; regulation of transcription by RNA polymerase II [GO:0006357] cytoplasm [GO:0005737]; cytosol [GO:0005829]; histone acetyltransferase complex [GO:0000123]; MOZ/MORF histone acetyltransferase complex [GO:0070776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] acetyltransferase activator activity [GO:0010698]; DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.9612 -2.056 ESYFESHNK 12.9891 0 0 8.53559 0 0 0 0 0 0 0 0 0 9.78067 0 0 0 0 0 0 0 0 10.4369 0 0 0 0 P55211 CASP9_HUMAN Caspase-9 (CASP-9) (EC 3.4.22.62) (Apoptotic protease Mch-6) (Apoptotic protease-activating factor 3) (APAF-3) (ICE-like apoptotic protease 6) (ICE-LAP6) [Cleaved into: Caspase-9 subunit p35; Caspase-9 subunit p10] CASP9 MCH6 Homo sapiens (Human) activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to UV [GO:0034644]; DNA damage response [GO:0006974]; epithelial cell apoptotic process [GO:1904019]; fibroblast apoptotic process [GO:0044346]; glial cell apoptotic process [GO:0034349]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; kidney development [GO:0001822]; leukocyte apoptotic process [GO:0071887]; neuron apoptotic process [GO:0051402]; platelet formation [GO:0030220]; positive regulation of apoptotic process [GO:0043065]; positive regulation of neuron apoptotic process [GO:0043525]; protein maturation [GO:0051604]; response to antibiotic [GO:0046677]; response to cobalt ion [GO:0032025]; response to estradiol [GO:0032355]; response to ischemia [GO:0002931]; response to lipopolysaccharide [GO:0032496]; signal transduction in response to DNA damage [GO:0042770] apoptosome [GO:0043293]; caspase complex [GO:0008303]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] cysteine-type endopeptidase activity [GO:0004197]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097199]; enzyme activator activity [GO:0008047]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; protein kinase binding [GO:0019901]; SH3 domain binding [GO:0017124] 0.27184 0.84099 AGSGSRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.37036 P55259 GP2_HUMAN Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) GP2 Homo sapiens (Human) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endosome [GO:0005768]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; zymogen granule membrane [GO:0042589] antigen binding [GO:0003823] 0.95477 -1.5193 ADLVKYFIIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.863 0 0 0 0 0 0 0 0 0 0 0 P55263 ADK_HUMAN Adenosine kinase (AK) (EC 2.7.1.20) (Adenosine 5'-phosphotransferase) ADK Homo sapiens (Human) AMP salvage [GO:0044209]; dAMP salvage [GO:0106383]; dATP biosynthetic process [GO:0006175]; GMP salvage [GO:0032263]; phosphorylation [GO:0016310]; purine nucleobase metabolic process [GO:0006144]; purine ribonucleoside salvage [GO:0006166]; ribonucleoside monophosphate biosynthetic process [GO:0009156] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] adenosine kinase activity [GO:0004001]; ATP binding [GO:0005524]; deoxyadenosine kinase activity [GO:0004136]; metal ion binding [GO:0046872]; RNA binding [GO:0003723] 0.92948 -1.2413 TQALPKMNSK 0 0 0 0 0 0 0 0 9.34848 0 0 0 0 0 0 10.5745 0 0 0 0 0 0 0 0 0 0 0 P55265 DSRAD_HUMAN Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (136 kDa double-stranded RNA-binding protein) (p136) (Interferon-inducible protein 4) (IFI-4) (K88DSRBP) ADAR ADAR1 DSRAD G1P1 IFI4 Homo sapiens (Human) adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; definitive hemopoiesis [GO:0060216]; erythrocyte differentiation [GO:0030218]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell homeostasis [GO:0061484]; hepatocyte apoptotic process [GO:0097284]; innate immune response [GO:0045087]; mRNA processing [GO:0006397]; negative regulation of hepatocyte apoptotic process [GO:1903944]; negative regulation of post-transcriptional gene silencing by RNA [GO:1900369]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; osteoblast differentiation [GO:0001649]; positive regulation of viral genome replication [GO:0045070]; pre-miRNA processing [GO:0031054]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; response to interferon-alpha [GO:0035455]; response to virus [GO:0009615]; RISC complex assembly [GO:0070922]; RNA processing [GO:0006396]; somatic diversification of immune receptors via somatic mutation [GO:0002566] cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; supraspliceosomal complex [GO:0044530] DNA binding [GO:0003677]; double-stranded RNA adenosine deaminase activity [GO:0003726]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; tRNA-specific adenosine deaminase activity [GO:0008251] 0.89916 -0.65533 EKICDYLFNVSDSSALNLAK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.90725 0 0 11.2361 9.54728 0 0 0 0 9.63214 0 0 10.2802 0 P55268 LAMB2_HUMAN Laminin subunit beta-2 (Laminin B1s chain) (Laminin-11 subunit beta) (Laminin-14 subunit beta) (Laminin-15 subunit beta) (Laminin-3 subunit beta) (Laminin-4 subunit beta) (Laminin-7 subunit beta) (Laminin-9 subunit beta) (S-laminin subunit beta) (S-LAM beta) LAMB2 LAMS Homo sapiens (Human) astrocyte development [GO:0014002]; axon extension involved in regeneration [GO:0048677]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; metanephric glomerular basement membrane development [GO:0072274]; metanephric podocyte development [GO:0072249]; neuromuscular junction development [GO:0007528]; positive regulation of cell adhesion [GO:0045785]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of basement membrane organization [GO:0110011]; retina development in camera-type eye [GO:0060041]; Schwann cell development [GO:0014044]; visual perception [GO:0007601] basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; laminin-11 complex [GO:0043260]; laminin-3 complex [GO:0005608]; neuromuscular junction [GO:0031594]; protein complex involved in cell-matrix adhesion [GO:0098637]; synaptic cleft [GO:0043083] extracellular matrix structural constituent [GO:0005201]; integrin binding [GO:0005178]; structural constituent of synapse-associated extracellular matrix [GO:0150043]; structural molecule activity [GO:0005198] 0.96738 -2.8584 ALSSAGERAR 11.6877 13.0269 12.855 0 0 0 11.3691 11.2241 9.80574 10.7628 10.8116 10.6874 0 0 0 0 0 0 0 0 0 0 10.6923 0 0 0 0 P55273 CDN2D_HUMAN Cyclin-dependent kinase 4 inhibitor D (p19-INK4d) CDKN2D Homo sapiens (Human) autophagic cell death [GO:0048102]; cell cycle [GO:0007049]; DNA synthesis involved in DNA repair [GO:0000731]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; negative regulation of phosphorylation [GO:0042326]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; response to retinoic acid [GO:0032526]; response to UV [GO:0009411]; response to vitamin D [GO:0033280]; sensory perception of sound [GO:0007605] cyclin D2-CDK4 complex [GO:0097129]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; protein kinase binding [GO:0019901] 0.87026 0.033905 ELVHPDALNR 0 0 0 0 0 0 0 0 9.13553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P55285 CADH6_HUMAN Cadherin-6 (Kidney cadherin) (K-cadherin) CDH6 Homo sapiens (Human) adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; Notch signaling pathway [GO:0007219]; synaptic membrane adhesion [GO:0099560] adherens junction [GO:0005912]; catenin complex [GO:0016342]; cell junction [GO:0030054]; glutamatergic synapse [GO:0098978]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] cadherin binding [GO:0045296]; calcium ion binding [GO:0005509] 0.84637 0.17326 FLYLGPFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.52023 P55287 CAD11_HUMAN Cadherin-11 (OSF-4) (Osteoblast cadherin) (OB-cadherin) CDH11 Homo sapiens (Human) adherens junction organization [GO:0034332]; aortic valve formation [GO:0003189]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell morphogenesis [GO:0000902]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; corticospinal tract morphogenesis [GO:0021957]; focal adhesion assembly [GO:0048041]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of cell migration [GO:0030336]; ossification [GO:0001503]; skeletal system development [GO:0001501] adherens junction [GO:0005912]; catenin complex [GO:0016342]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685] cadherin binding [GO:0045296]; calcium ion binding [GO:0005509] 0.61226 0.42713 FFTINPEDGFIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.85145 0 0 0 0 0 8.97384 0 0 8.08513 0 0 0 P55289 CAD12_HUMAN Cadherin-12 (Brain cadherin) (BR-cadherin) (Neural type cadherin 2) (N-cadherin 2) CDH12 Homo sapiens (Human) adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] adherens junction [GO:0005912]; catenin complex [GO:0016342]; plasma membrane [GO:0005886] cadherin binding [GO:0045296]; calcium ion binding [GO:0005509] 0.87278 0.031415 ESTAQYNFSIIASK 0 0 0 0 9.86927 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P55316 FOXG1_HUMAN Forkhead box protein G1 (Brain factor 1) (BF-1) (BF1) (Brain factor 2) (BF-2) (BF2) (hBF-2) (Forkhead box protein G1A) (Forkhead box protein G1B) (Forkhead box protein G1C) (Forkhead-related protein FKHL1) (HFK1) (Forkhead-related protein FKHL2) (HFK2) (Forkhead-related protein FKHL3) (HFK3) FOXG1 FKH2 FKHL1 FKHL2 FKHL3 FKHL4 FOXG1A FOXG1B FOXG1C Homo sapiens (Human) aging [GO:0007568]; axon midline choice point recognition [GO:0016199]; brain development [GO:0007420]; dorsal/ventral pattern formation [GO:0009953]; inner ear morphogenesis [GO:0042472]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; positive regulation of cell cycle [GO:0045787]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron differentiation [GO:0045666]; pyramidal neuron migration to cerebral cortex [GO:0021852]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96311 -2.1642 ADGLGGK 0 8.25593 0 0 0 0 0 9.06418 0 0 0 0 0 0 0 0 0 0 8.93325 0 0 0 0 0 0 0 0 P55347 PKNX1_HUMAN Homeobox protein PKNOX1 (Homeobox protein PREP-1) (PBX/knotted homeobox 1) PKNOX1 PREP1 Homo sapiens (Human) angiogenesis [GO:0001525]; camera-type eye development [GO:0043010]; erythrocyte differentiation [GO:0030218]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; T cell differentiation [GO:0030217]; transcription by RNA polymerase II [GO:0006366] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "chromatin binding [GO:0003682]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.83082 0.20218 QEKEGKPFFCEDPETDNLMVK 9.49783 0 0 0 0 0 0 0 9.85989 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P55735 SEC13_HUMAN Protein SEC13 homolog (GATOR complex protein SEC13) (SEC13-like protein 1) (SEC13-related protein) SEC13 D3S1231E SEC13A SEC13L1 SEC13R Homo sapiens (Human) COPII-coated vesicle budding [GO:0090114]; COPII-coated vesicle cargo loading [GO:0090110]; intracellular protein transport [GO:0006886]; mRNA transport [GO:0051028]; negative regulation of TORC1 signaling [GO:1904262]; nucleocytoplasmic transport [GO:0006913]; positive regulation of TOR signaling [GO:0032008]; positive regulation of TORC1 signaling [GO:1904263]; protein exit from endoplasmic reticulum [GO:0032527]; protein import into nucleus [GO:0006606] COPII vesicle coat [GO:0030127]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; GATOR2 complex [GO:0061700]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nuclear pore outer ring [GO:0031080]; nucleoplasm [GO:0005654] identical protein binding [GO:0042802]; structural molecule activity [GO:0005198] 0.82574 0.21431 LEAHSDWVR 0 0 0 0 0 0 0 0 0 9.56759 0 9.52213 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P55771 PAX9_HUMAN Paired box protein Pax-9 PAX9 Homo sapiens (Human) anatomical structure development [GO:0048856]; cellular response to growth factor stimulus [GO:0071363]; endoderm development [GO:0007492]; face morphogenesis [GO:0060325]; negative regulation of DNA-templated transcription [GO:0045892]; odontogenesis [GO:0042476]; regulation of odontogenesis [GO:0042481]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.76104 0.29138 EGSHSVTASAL 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.61802 0 0 0 0 0 0 0 0 0 P55786 PSA_HUMAN Puromycin-sensitive aminopeptidase (PSA) (EC 3.4.11.14) (Cytosol alanyl aminopeptidase) (AAP-S) NPEPPS PSA Homo sapiens (Human) cellular response to hypoxia [GO:0071456]; peptide catabolic process [GO:0043171]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein polyubiquitination [GO:0000209]; proteolysis [GO:0006508] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634] aminopeptidase activity [GO:0004177]; metalloaminopeptidase activity [GO:0070006]; peptide binding [GO:0042277]; zinc ion binding [GO:0008270] 0.0081301 2.0977 DLSLPPVDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.87954 0 9.83851 0 0 10.1167 0 0 P55795 HNRH2_HUMAN "Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (FTP-3) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed]" HNRNPH2 FTP3 HNRPH2 Homo sapiens (Human) regulation of RNA splicing [GO:0043484] cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; ribonucleoprotein complex [GO:1990904] RNA binding [GO:0003723] 0 3.7925 ATENDIYNFFSPLNPMR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.33316 0 0 0 0 P55809 SCOT1_HUMAN "Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (SCOT) (EC 2.8.3.5) (3-oxoacid CoA-transferase 1) (Somatic-type succinyl-CoA:3-oxoacid CoA-transferase) (SCOT-s) (Succinyl-CoA:3-oxoacid CoA transferase)" OXCT1 OXCT SCOT Homo sapiens (Human) adipose tissue development [GO:0060612]; brain development [GO:0007420]; cellular ketone body metabolic process [GO:0046950]; heart development [GO:0007507]; ketone body catabolic process [GO:0046952]; ketone catabolic process [GO:0042182]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to xenobiotic stimulus [GO:0009410] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] identical protein binding [GO:0042802]; succinyl-CoA:3-oxo-acid CoA-transferase activity [GO:0008260] 0.93284 -1.2785 LSIRKEGDGEAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.623 0 0 0 0 0 0 0 0 0 0 P55884 EIF3B_HUMAN Eukaryotic translation initiation factor 3 subunit B (eIF3b) (Eukaryotic translation initiation factor 3 subunit 9) (Prt1 homolog) (hPrt1) (eIF-3-eta) (eIF3 p110) (eIF3 p116) EIF3B EIF3S9 Homo sapiens (Human) formation of cytoplasmic translation initiation complex [GO:0001732]; IRES-dependent viral translational initiation [GO:0075522]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413]; viral translational termination-reinitiation [GO:0075525] "cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; eukaryotic 43S preinitiation complex [GO:0016282]; eukaryotic 48S preinitiation complex [GO:0033290]; eukaryotic translation initiation factor 3 complex [GO:0005852]; eukaryotic translation initiation factor 3 complex, eIF3m [GO:0071541]; extracellular exosome [GO:0070062]; synapse [GO:0045202]" molecular adaptor activity [GO:0060090]; RNA binding [GO:0003723]; translation initiation factor activity [GO:0003743]; translation initiation factor binding [GO:0031369] 0.00978 1.8102 GTQGVVTNFEIFR 0 0 0 0 0 0 0 0 0 0 0 0 0 8.88719 0 0 9.23977 0 0 0 0 0 0 0 0 0 0 P55895 RAG2_HUMAN V(D)J recombination-activating protein 2 (RAG-2) RAG2 Homo sapiens (Human) B cell differentiation [GO:0030183]; B cell homeostatic proliferation [GO:0002358]; B cell lineage commitment [GO:0002326]; chromatin organization [GO:0006325]; defense response to bacterium [GO:0042742]; DN2 thymocyte differentiation [GO:1904155]; mature B cell differentiation involved in immune response [GO:0002313]; negative regulation of T cell differentiation in thymus [GO:0033085]; organ growth [GO:0035265]; positive regulation of organ growth [GO:0046622]; pre-B cell allelic exclusion [GO:0002331]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; V(D)J recombination [GO:0033151] DNA recombinase complex [GO:0097519]; nucleoplasm [GO:0005654] "chromatin binding [GO:0003682]; methylated histone binding [GO:0035064]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; sequence-specific DNA binding [GO:0043565]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270]" 0.89894 -0.57283 QVVSEGFYFYMLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.59347 0 0 P56159 GFRA1_HUMAN GDNF family receptor alpha-1 (GDNF receptor alpha-1) (GDNFR-alpha-1) (GFR-alpha-1) (RET ligand 1) (TGF-beta-related neurotrophic factor receptor 1) GFRA1 GDNFRA RETL1 TRNR1 Homo sapiens (Human) aging [GO:0007568]; cell migration [GO:0016477]; cell surface receptor signaling pathway [GO:0007166]; kidney development [GO:0001822]; male gonad development [GO:0008584]; nervous system development [GO:0007399]; neuron projection development [GO:0031175]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731] axon [GO:0030424]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; plasma membrane protein complex [GO:0098797]; receptor complex [GO:0043235] glial cell-derived neurotrophic factor receptor activity [GO:0016167]; integrin binding [GO:0005178]; neurotrophin receptor activity [GO:0005030]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102] 0.96996 -4.4014 ALRQFFDK 0 0 9.26901 0 0 0 0 0 0 0 0 0 0 0 12.2563 0 0 0 0 0 0 0 0 0 0 0 0 P56177 DLX1_HUMAN Homeobox protein DLX-1 DLX1 Homo sapiens (Human) cell differentiation [GO:0030154]; cellular response to BMP stimulus [GO:0071773]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cerebral cortex GABAergic interneuron fate commitment [GO:0021893]; embryonic skeletal system development [GO:0048706]; forebrain neuron differentiation [GO:0021879]; hippocampus development [GO:0021766]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cellular response to transforming growth factor beta stimulus [GO:1903845]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of photoreceptor cell differentiation [GO:0046533]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuroblast differentiation [GO:0014016]; neuron apoptotic process [GO:0051402]; Notch signaling pathway [GO:0007219]; odontogenesis of dentin-containing tooth [GO:0042475]; oligodendrocyte differentiation [GO:0048709]; positive regulation of amacrine cell differentiation [GO:1902871]; positive regulation of cell differentiation [GO:0045597]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proximal/distal pattern formation [GO:0009954]; subpallium development [GO:0021544] chromatin [GO:0000785]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.87344 0.031629 STVVEGGEVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.93927 0 P56178 DLX5_HUMAN Homeobox protein DLX-5 DLX5 Homo sapiens (Human) anatomical structure formation involved in morphogenesis [GO:0048646]; BMP signaling pathway [GO:0030509]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to BMP stimulus [GO:0071773]; embryonic limb morphogenesis [GO:0030326]; endochondral ossification [GO:0001958]; epithelial cell differentiation [GO:0030855]; face morphogenesis [GO:0060325]; inner ear morphogenesis [GO:0042472]; interneuron axon guidance [GO:0097376]; nervous system development [GO:0007399]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory pit development [GO:0060166]; osteoblast differentiation [GO:0001649]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; regulation of transcription by RNA polymerase II [GO:0006357]; roof of mouth development [GO:0060021]; skeletal system development [GO:0001501] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; HMG box domain binding [GO:0071837]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]" 0.88315 -0.10572 MTGVFDRRVPSIR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1313 0 0 0 0 0 0 0 0 0 0 0 0 0 P56179 DLX6_HUMAN Homeobox protein DLX-6 DLX6 Homo sapiens (Human) anatomical structure formation involved in morphogenesis [GO:0048646]; cell differentiation [GO:0030154]; embryonic limb morphogenesis [GO:0030326]; epithelial cell differentiation [GO:0030855]; head development [GO:0060322]; inner ear morphogenesis [GO:0042472]; nervous system development [GO:0007399]; positive regulation of epithelial cell proliferation [GO:0050679]; regulation of transcription by RNA polymerase II [GO:0006357]; roof of mouth development [GO:0060021]; skeletal system development [GO:0001501] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.74987 0.31329 TTVIENGEIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.93595 0 0 0 0 0 P56180 TPTE_HUMAN Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Cancer/testis antigen 44) (CT44) (Transmembrane phosphatase with tensin homology) (Tumor antigen BJ-HCC-5) TPTE Homo sapiens (Human) dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]; signal transduction [GO:0007165] cytosol [GO:0005829]; membrane [GO:0016020] "phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; protein tyrosine phosphatase activity [GO:0004725]" 0.96945 -3.5493 ESLYYFGER 0 0 0 0 0 0 0 0 0 0 9.89028 0 0 13.0919 0 0 0 0 0 0 12.3872 0 0 0 0 0 0 P56182 RRP1_HUMAN Ribosomal RNA processing protein 1 homolog A (Novel nuclear protein 1) (NNP-1) (Nucleolar protein Nop52) (RRP1-like protein) RRP1 D21S2056E NNP1 NOP52 RRP1A Homo sapiens (Human) rRNA processing [GO:0006364] "chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleus [GO:0005634]; preribosome, small subunit precursor [GO:0030688]" RNA binding [GO:0003723] 0.95998 -1.9789 AEPEAGEEQAGDDR 0 0 9.28697 0 0 0 0 0 0 11.3831 0 0 0 0 10.1768 0 0 0 0 0 0 0 0 0 0 0 0 P56192 SYMC_HUMAN "Methionine--tRNA ligase, cytoplasmic (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS)" MARS1 MARS Homo sapiens (Human) cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; methionyl-tRNA aminoacylation [GO:0006431]; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901838]; rRNA transcription [GO:0009303]; tRNA aminoacylation for protein translation [GO:0006418] aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleolus [GO:0005730] ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049] 0.80841 0.22882 GVGVFGDMAQDTGIPADIWR 0 0 0 0 8.68243 0 11.0292 0 11.112 0 8.98812 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P56199 ITA1_HUMAN Integrin alpha-1 (CD49 antigen-like family member A) (Laminin and collagen receptor) (VLA-1) (CD antigen CD49a) ITGA1 Homo sapiens (Human) cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; cellular extravasation [GO:0045123]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neuron projection morphogenesis [GO:0048812]; neutrophil chemotaxis [GO:0030593]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; vasodilation [GO:0042311] acrosomal vesicle [GO:0001669]; basal part of cell [GO:0045178]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin alpha1-beta1 complex [GO:0034665]; integrin complex [GO:0008305]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; plasma membrane [GO:0005886] collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; protein phosphatase binding [GO:0019903] 0.95919 -1.7622 DVAVVKVTMNFEPNK 0 0 0 0 0 0 0 0 0 10.7056 9.02885 11.8164 0 0 0 0 0 11.2486 0 0 0 0 0 0 0 0 0 P56211 ARP19_HUMAN cAMP-regulated phosphoprotein 19 (ARPP-19) ARPP19 Homo sapiens (Human) cell division [GO:0051301]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; negative regulation of protein dephosphorylation [GO:0035308]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of glucose import [GO:0046326] cytoplasm [GO:0005737]; nucleoplasm [GO:0005654] phosphatase inhibitor activity [GO:0019212]; potassium channel regulator activity [GO:0015459]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase inhibitor activity [GO:0004864]; protein phosphatase regulator activity [GO:0019888]; signaling receptor binding [GO:0005102] 0.88212 -0.30057 VTSPEKAEEAK 0 0 0 0 0 0 0 0 0 0 0 0 10.2583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P56270 MAZ_HUMAN Myc-associated zinc finger protein (MAZI) (Pur-1) (Purine-binding transcription factor) (Serum amyloid A-activating factor-1) (SAF-1) (Transcription factor Zif87) (ZF87) (Zinc finger protein 801) MAZ ZNF801 Homo sapiens (Human) negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of transcription by RNA polymerase II [GO:0006357]; termination of RNA polymerase II transcription [GO:0006369]; transcription initiation at RNA polymerase II promoter [GO:0006367] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.63228 0.39959 NHACEMCGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.07959 0 0 0 0 P56279 TCL1A_HUMAN T-cell leukemia/lymphoma protein 1A (Oncogene TCL-1) (Oncogene TCL1) (Protein p14 TCL1) TCL1A TCL1 Homo sapiens (Human) cellular response to tumor necrosis factor [GO:0071356]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of protein-containing complex assembly [GO:0031334] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991] identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activator activity [GO:0043539] 0.88217 -0.30076 YRSSDSSFWR 0 0 0 0 0 0 0 0 0 10.0542 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P56282 DPOE2_HUMAN DNA polymerase epsilon subunit 2 (DNA polymerase II subunit 2) (DNA polymerase epsilon subunit B) POLE2 DPE2 Homo sapiens (Human) DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA-templated DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276] epsilon DNA polymerase complex [GO:0008622]; intracellular membrane-bounded organelle [GO:0043231]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654] DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887] 0.93996 -1.3268 APERLRSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3424 0 0 0 0 0 0 0 0 0 P56373 P2RX3_HUMAN P2X purinoceptor 3 (P2X3) (ATP receptor) (Purinergic receptor) P2RX3 Homo sapiens (Human) behavioral response to formalin induced pain [GO:0061368]; cellular response to ATP [GO:0071318]; establishment of localization in cell [GO:0051649]; inorganic cation transmembrane transport [GO:0098662]; neuromuscular synaptic transmission [GO:0007274]; neuronal action potential [GO:0019228]; peristalsis [GO:0030432]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of sensory perception of pain [GO:1904058]; protein homotrimerization [GO:0070207]; regulation of synaptic plasticity [GO:0048167]; response to carbohydrate [GO:0009743]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; sensory perception of taste [GO:0050909]; signal transduction [GO:0007165]; urinary bladder smooth muscle contraction [GO:0014832] dendritic spine [GO:0043197]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; rough endoplasmic reticulum [GO:0005791]; Schaffer collateral - CA1 synapse [GO:0098685]; terminal bouton [GO:0043195] ATP binding [GO:0005524]; extracellularly ATP-gated monoatomic cation channel activity [GO:0004931]; identical protein binding [GO:0042802]; purinergic nucleotide receptor activity [GO:0001614] 0.72795 0.3495 AWDQCIPK 0 0 0 9.9292 0 0 0 0 0 0 9.23695 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P56381 ATP5E_HUMAN "ATP synthase subunit epsilon, mitochondrial (ATPase subunit epsilon) (ATP synthase F1 subunit epsilon)" ATP5F1E ATP5E Homo sapiens (Human) proton motive force-driven ATP synthesis [GO:0015986]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776] "mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial proton-transporting ATP synthase complex [GO:0005753]; mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1) [GO:0000275]" "hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]" 0.9543 -1.5055 TEFKANAEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.86813 0 0 0 0 0 0 0 0 P56589 PEX3_HUMAN Peroxisomal biogenesis factor 3 (Peroxin-3) (Peroxisomal assembly protein PEX3) PEX3 Homo sapiens (Human) peroxisome organization [GO:0007031]; protein import into peroxisome membrane [GO:0045046] endoplasmic reticulum [GO:0005783]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; protein-lipid complex [GO:0032994] lipid binding [GO:0008289]; protein-macromolecule adaptor activity [GO:0030674] 0.56017 0.51829 LEIWEDLK 0 0 0 0 0 0 0 0 0 10.7896 11.0321 11.0065 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P56645 PER3_HUMAN Period circadian protein homolog 3 (hPER3) (Cell growth-inhibiting gene 13 protein) (Circadian clock protein PERIOD 3) PER3 GIG13 Homo sapiens (Human) "circadian regulation of gene expression [GO:0032922]; entrainment of circadian clock by photoperiod [GO:0043153]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein stabilization [GO:0050821]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]" cytoplasm [GO:0005737]; nucleus [GO:0005634] kinase binding [GO:0019900]; transcription cis-regulatory region binding [GO:0000976]; transcription corepressor binding [GO:0001222]; ubiquitin protein ligase binding [GO:0031625] 0.92367 -1.1677 ISQNGQQSQDVQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.34509 0 0 0 0 0 0 P56703 WNT3_HUMAN Proto-oncogene Wnt-3 (Proto-oncogene Int-4 homolog) WNT3 INT4 Homo sapiens (Human) anterior/posterior axis specification [GO:0009948]; axon guidance [GO:0007411]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation [GO:0044338]; canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904954]; canonical Wnt signaling pathway involved in osteoblast differentiation [GO:0044339]; canonical Wnt signaling pathway involved in stem cell proliferation [GO:1905474]; cell fate commitment [GO:0045165]; cell morphogenesis [GO:0000902]; cellular response to retinoic acid [GO:0071300]; dorsal/ventral axis specification [GO:0009950]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; gamete generation [GO:0007276]; gene expression [GO:0010467]; head morphogenesis [GO:0060323]; limb bud formation [GO:0060174]; mammary gland epithelium development [GO:0061180]; mesoderm formation [GO:0001707]; negative regulation of axon extension involved in axon guidance [GO:0048843]; neuron differentiation [GO:0030182]; positive regulation of collateral sprouting in absence of injury [GO:0048697]; positive regulation of gene expression [GO:0010628]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of neurogenesis [GO:0050767]; Spemann organizer formation at the anterior end of the primitive streak [GO:0060064]; stem cell proliferation [GO:0072089] endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; Wnt signalosome [GO:1990909] cytokine activity [GO:0005125]; frizzled binding [GO:0005109]; protein domain specific binding [GO:0019904]; receptor ligand activity [GO:0048018] 0.93007 -1.2446 ESRGWVETLR 0 0 0 0 0 11.3432 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.53041 0 0 P56706 WNT7B_HUMAN Protein Wnt-7b WNT7B Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; central nervous system vasculogenesis [GO:0022009]; chorio-allantoic fusion [GO:0060710]; developmental growth involved in morphogenesis [GO:0060560]; embryonic organ development [GO:0048568]; embryonic placenta morphogenesis [GO:0060669]; establishment or maintenance of polarity of embryonic epithelium [GO:0016332]; fibroblast proliferation [GO:0048144]; forebrain regionalization [GO:0021871]; homeostatic process [GO:0042592]; in utero embryonic development [GO:0001701]; inner medullary collecting duct development [GO:0072061]; intracellular oxygen homeostasis [GO:0032364]; lens fiber cell development [GO:0070307]; lobar bronchus development [GO:0060482]; lung development [GO:0030324]; lung epithelium development [GO:0060428]; lung morphogenesis [GO:0060425]; mammary gland epithelium development [GO:0061180]; metanephric collecting duct development [GO:0072205]; metanephric epithelium development [GO:0072207]; metanephric loop of Henle development [GO:0072236]; metanephros morphogenesis [GO:0003338]; neuron differentiation [GO:0030182]; neuron projection morphogenesis [GO:0048812]; outer medullary collecting duct development [GO:0072060]; positive regulation of JNK cascade [GO:0046330]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell projection size [GO:0032536]; renal inner medulla development [GO:0072053]; renal outer medulla development [GO:0072054]; response to glucocorticoid [GO:0051384]; stem cell proliferation [GO:0072089]; synapse organization [GO:0050808]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055] endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886] cytokine activity [GO:0005125]; frizzled binding [GO:0005109]; receptor ligand activity [GO:0048018] 0.8836 -0.04786 FGRWNCSALGEKTVFGQELR 0 0 0 0 0 0 0 0 8.68643 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.88448 P56715 RP1_HUMAN Oxygen-regulated protein 1 (Retinitis pigmentosa 1 protein) (Retinitis pigmentosa RP1 protein) RP1 ORP1 Homo sapiens (Human) "axoneme assembly [GO:0035082]; cellular response to light stimulus [GO:0071482]; intracellular signal transduction [GO:0035556]; photoreceptor cell development [GO:0042461]; photoreceptor cell maintenance [GO:0045494]; photoreceptor cell outer segment organization [GO:0035845]; phototransduction, visible light [GO:0007603]; positive regulation of non-motile cilium assembly [GO:1902857]; retina development in camera-type eye [GO:0060041]; retinal cone cell development [GO:0046549]; retinal rod cell development [GO:0046548]; visual perception [GO:0007601]" axoneme [GO:0005930]; ciliary tip [GO:0097542]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; photoreceptor connecting cilium [GO:0032391]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750] microtubule binding [GO:0008017] 0.9543 -1.5308 EQDMVPIDLSANCSTVNIQSVPK 0 9.8024 0 0 0 0 0 0 11.589 0 0 11.9187 0 0 0 0 0 0 0 0 0 0 10.1552 0 0 0 0 P56730 NETR_HUMAN Neurotrypsin (EC 3.4.21.-) (Leydin) (Motopsin) (Serine protease 12) PRSS12 Homo sapiens (Human) exocytosis [GO:0006887]; zymogen activation [GO:0031638] axon [GO:0030424]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; terminal bouton [GO:0043195] scavenger receptor activity [GO:0005044]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236] 0.96274 -2.6669 ASGNSNK 0 0 0 0 8.43979 0 0 0 0 11.0757 0 9.70216 0 0 0 0 0 0 0 0 0 0 0 0 10.2725 0 0 P56748 CLD8_HUMAN Claudin-8 CLDN8 UNQ779/PRO1573 Homo sapiens (Human) bicellular tight junction assembly [GO:0070830]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155] apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; endoplasmic reticulum [GO:0005783]; plasma membrane [GO:0005886] identical protein binding [GO:0042802]; structural molecule activity [GO:0005198] 0.88432 -0.29854 TTQKSYHTGK 0 0 0 0 0 0 0 8.87857 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P56750 CLD17_HUMAN Claudin-17 CLDN17 UNQ758/PRO1489 Homo sapiens (Human) bicellular tight junction assembly [GO:0070830]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155] bicellular tight junction [GO:0005923]; chloride channel complex [GO:0034707]; plasma membrane [GO:0005886] chloride channel activity [GO:0005254]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198] 0.87311 0.025946 LWEGLWMNCIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.22477 0 0 0 0 0 0 0 0 0 0 0 0 P56851 EP3B_HUMAN Epididymal secretory protein E3-beta (Human epididymis-specific protein 3-beta) (HE3-beta) EDDM3B FAM12B HE3B UNQ6412/PRO21187 Homo sapiens (Human) extracellular region [GO:0005576] 0.88603 -0.33976 EVSWREFMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.94831 0 0 0 0 0 P57053 H2BFS_HUMAN Histone H2B type F-S (H2B-clustered histone 12 like) (H2B.S histone 1) (Histone H2B.s) (H2B/s) H2BC12L H2BFS H2BS1 Homo sapiens (Human) antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response in mucosa [GO:0002227]; substantia nigra development [GO:0021762] cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634] DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; structural constituent of chromatin [GO:0030527] 0 12.45 AMGIMNSFVNDIFER 11.95 11.8807 12.3708 0 0 0 12.7515 12.8587 9.19911 12.5409 13.3567 12.7606 10.2394 10.5829 9.80892 12.0209 9.98399 9.29526 12.9062 12.5902 12.474 11.4067 11.268 11.2758 13.6467 13.5697 13.4624 P57055 DSCR6_HUMAN Protein ripply3 (Down syndrome critical region protein 6) RIPPLY3 DSCR6 Homo sapiens (Human) cell population proliferation [GO:0008283]; embryonic pattern specification [GO:0009880]; heart development [GO:0007507]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pharyngeal system development [GO:0060037] nucleus [GO:0005634] 0.9546 -1.5221 QENGPGGKGR 0 0 0 0 0 0 0 0 0 9.09919 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P57058 HUNK_HUMAN Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (B19) (Serine/threonine-protein kinase MAK-V) HUNK MAKV Homo sapiens (Human) intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] cytoplasm [GO:0005737] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.93245 -1.2639 DLEFHAVQDK 0 0 0 0 8.79568 9.99393 0 0 0 0 10.4631 0 0 0 0 0 0 0 0 0 0 0 0 0 9.83569 0 0 P57071 PRD15_HUMAN PR domain zinc finger protein 15 (EC 2.1.1.-) (PR domain-containing protein 15) (Zinc finger protein 298) PRDM15 C21orf83 ZNF298 Homo sapiens (Human) methylation [GO:0032259]; negative regulation of MAPK cascade [GO:0043409]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of stem cell division [GO:2000035]; regulation of transcription by RNA polymerase II [GO:0006357] nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; methyltransferase activity [GO:0008168]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.95756 -1.6619 DIALMDDHQR 0 0 10.1819 0 0 0 0 0 0 12.6263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P57076 CF298_HUMAN Cilia- and flagella-associated protein 298 (Protein kurly homolog) CFAP298 C21orf48 C21orf59 Homo sapiens (Human) cilium assembly [GO:0060271]; regulation of cilium movement [GO:0003352] cilium [GO:0005929]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; nucleus [GO:0005634] 0.96981 -3.3038 GQGAPAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.80742 0 0 0 0 0 0 0 0 0 0 P57081 WDR4_HUMAN tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 (Protein Wuho homolog) (hWH) (WD repeat-containing protein 4) WDR4 Homo sapiens (Human) DNA damage response [GO:0006974]; tRNA (guanine-N7)-methylation [GO:0106004]; tRNA modification [GO:0006400] chromosome [GO:0005694]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tRNA (m7G46) methyltransferase complex [GO:0106143]; tRNA methyltransferase complex [GO:0043527] enzyme activator activity [GO:0008047] 0.7718 0.27111 ATFDNVTSYLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.52529 0 P57086 SCND1_HUMAN SCAN domain-containing protein 1 SCAND1 SDP1 Homo sapiens (Human) positive regulation of DNA-templated transcription [GO:0045893] nucleus [GO:0005634] 0.88144 -0.30883 QFRYQDAAGPR 0 0 0 0 0 0 0 0 8.46915 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P57087 JAM2_HUMAN Junctional adhesion molecule B (JAM-B) (Junctional adhesion molecule 2) (JAM-2) (Vascular endothelial junction-associated molecule) (VE-JAM) (CD antigen CD322) JAM2 C21orf43 VEJAM UNQ219/PRO245 Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cellular extravasation [GO:0045123]; hematopoietic stem cell migration to bone marrow [GO:0097241]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte tethering or rolling [GO:0050901]; lymphocyte aggregation [GO:0071593]; maintenance of blood-brain barrier [GO:0035633]; myoblast fusion [GO:0007520]; negative regulation of myelination [GO:0031642]; positive regulation of lymphocyte migration [GO:2000403]; spermatid development [GO:0007286] bicellular tight junction [GO:0005923]; cell surface [GO:0009986]; cell-cell contact zone [GO:0044291]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]; somatodendritic compartment [GO:0036477]; tight junction [GO:0070160] integrin binding [GO:0005178] 0.92437 -1.0128 AEMIDFNIR 0 0 0 0 0 0 0 0 0 0 0 0 8.62242 0 0 0 0 9.83526 0 0 0 0 0 0 0 10.0348 9.52845 P57088 TMM33_HUMAN Transmembrane protein 33 (Protein DB83) (SHINC-3) TMEM33 DB83 Homo sapiens (Human) endoplasmic reticulum tubular network organization [GO:0071786]; innate immune response [GO:0045087]; membrane organization [GO:0061024]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of PERK-mediated unfolded protein response [GO:1903899]; regulation of endoplasmic reticulum tubular network organization [GO:1903371]; response to endoplasmic reticulum stress [GO:0034976] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; melanosome [GO:0042470]; nuclear envelope [GO:0005635] 0.047312 1.4538 ALLANALTSALR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.35271 0 0 P57103 NAC3_HUMAN Sodium/calcium exchanger 3 (Na(+)/Ca(2+)-exchange protein 3) (Solute carrier family 8 member 3) SLC8A3 NCX3 Homo sapiens (Human) calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; cell communication [GO:0007154]; cellular response to hypoxia [GO:0071456]; hematopoietic progenitor cell differentiation [GO:0002244]; intracellular calcium ion homeostasis [GO:0006874]; learning [GO:0007612]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transmembrane transport [GO:0006851]; modulation of excitatory postsynaptic potential [GO:0098815]; monoatomic ion transport [GO:0006811]; myelination [GO:0042552]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; oligodendrocyte differentiation [GO:0048709]; regulation of cardiac conduction [GO:1903779]; regulation of skeletal muscle contraction [GO:0014819]; sodium ion transmembrane transport [GO:0035725]; synapse organization [GO:0050808] anchoring junction [GO:0070161]; axon [GO:0030424]; axon terminus [GO:0043679]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; synapse [GO:0045202] calcium:sodium antiporter activity [GO:0005432]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; monoatomic ion antiporter activity involved in regulation of postsynaptic membrane potential [GO:0099580] 0.92343 -1.1618 EVDESRREMIR 0 0 0 0 0 0 10.2059 0 0 0 0 0 0 0 0 0 0 0 0 9.07535 0 0 0 0 0 0 0 P57105 SYJ2B_HUMAN Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25) SYNJ2BP OMP25 Homo sapiens (Human) negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of sprouting angiogenesis [GO:1903671]; protein targeting [GO:0006605]; regulation of endocytosis [GO:0030100]; regulation of Notch signaling pathway [GO:0008593]; Rho protein signal transduction [GO:0007266] mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739] 0.956 -1.5438 VQHRLQVQNGPIGHR 9.56093 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P57679 EVC_HUMAN EvC complex member EVC (DWF-1) (Ellis-van Creveld syndrome protein) EVC Homo sapiens (Human) cartilage development [GO:0051216]; endochondral bone growth [GO:0003416]; muscle organ development [GO:0007517]; positive regulation of smoothened signaling pathway [GO:0045880]; skeletal system development [GO:0001501]; smoothened signaling pathway [GO:0007224] ciliary basal body [GO:0036064]; ciliary membrane [GO:0060170]; cilium [GO:0005929]; cytoplasm [GO:0005737]; plasma membrane protein complex [GO:0098797] 0.8835 -0.10684 IMEDHEERKLQHLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.12435 0 0 0 0 0 0 0 0 0 P57727 TMPS3_HUMAN Transmembrane protease serine 3 (EC 3.4.21.-) (Serine protease TADG-12) (Tumor-associated differentially-expressed gene 12 protein) TMPRSS3 ECHOS1 TADG12 UNQ323/PRO382 Homo sapiens (Human) intracellular sodium ion homeostasis [GO:0006883]; proteolysis [GO:0006508]; sensory perception of sound [GO:0007605] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; neuronal cell body [GO:0043025] scavenger receptor activity [GO:0005044]; serine-type endopeptidase activity [GO:0004252]; sodium channel regulator activity [GO:0017080] 0.92412 -1.1721 SLFGLDDLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.53411 0 P57729 RAB38_HUMAN Ras-related protein Rab-38 (Melanoma antigen NY-MEL-1) RAB38 Homo sapiens (Human) endosome to melanosome transport [GO:0035646]; intracellular protein transport [GO:0006886]; melanosome assembly [GO:1903232]; melanosome organization [GO:0032438]; mitochondrion organization [GO:0007005]; phagosome acidification [GO:0090383]; platelet dense granule organization [GO:0060155]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of phosphatidylcholine biosynthetic process [GO:2001247]; positive regulation of protein localization to cell periphery [GO:1904377]; protein localization to membrane [GO:0072657]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192] cell body [GO:0044297]; cytosol [GO:0005829]; early endosome [GO:0005769]; endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; lysosome [GO:0005764]; melanosome [GO:0042470]; melanosome membrane [GO:0033162]; membrane [GO:0016020]; mitochondria-associated endoplasmic reticulum membrane [GO:0044233]; mitochondrion [GO:0005739]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802] AP-1 adaptor complex binding [GO:0035650]; AP-3 adaptor complex binding [GO:0035651]; BLOC-2 complex binding [GO:0036461]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924] 0.83125 0.20203 ATIGVDFALKVLHWDPETVVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.6765 0 0 0 0 0 0 0 0 P57737 CORO7_HUMAN Coronin-7 (Crn7) (70 kDa WD repeat tumor rejection antigen homolog) CORO7 Homo sapiens (Human) actin filament polymerization [GO:0030041]; cell migration [GO:0016477]; establishment of cell polarity [GO:0030010]; Golgi organization [GO:0007030]; Golgi to endosome transport [GO:0006895]; positive regulation of hippo signaling [GO:0035332]; protein transport [GO:0015031] cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; trans-Golgi network [GO:0005802] actin binding [GO:0003779] 0.92399 -1.0433 APSSAQYLEEK 0 0 0 0 0 0 0 0 8.25229 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7154 0 0 P57738 TCTA_HUMAN T-cell leukemia translocation-altered gene protein (T-cell leukemia translocation-associated gene protein) TCTA Homo sapiens (Human) negative regulation of osteoclast differentiation [GO:0045671]; osteoclast fusion [GO:0072675] membrane [GO:0016020] 0.84911 0.16405 EWEAQDMR 0 0 0 0 0 0 9.43421 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P57764 GSDMD_HUMAN "Gasdermin-D (Gasdermin domain-containing protein 1) [Cleaved into: Gasdermin-D, N-terminal (GSDMD-NT) (hGSDMD-NTD); Gasdermin-D, C-terminal (GSDMD-CT) (hGSDMD-CTD)]" GSDMD DFNA5L GSDMDC1 FKSG10 Homo sapiens (Human) cellular response to extracellular stimulus [GO:0031668]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; pore complex assembly [GO:0046931]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of interleukin-18 production [GO:0032741]; protein homooligomerization [GO:0051260]; protein secretion [GO:0009306]; pyroptosis [GO:0070269] cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; NLRP3 inflammasome complex [GO:0072559]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724] "cardiolipin binding [GO:1901612]; channel activator activity [GO:0099103]; phosphatidic acid binding [GO:0070300]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylserine binding [GO:0001786]; wide pore channel activity [GO:0022829]" 0.96736 -2.8044 HLRQPEHK 0 0 0 11.6644 0 0 0 0 0 9.33222 0 0 0 0 0 0 13.8455 13.5238 10.195 0 0 9.68224 0 0 0 0 0 P57768 SNX16_HUMAN Sorting nexin-16 SNX16 Homo sapiens (Human) early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; protein targeting to lysosome [GO:0006622] cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; extrinsic component of endosome membrane [GO:0031313]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lysosome [GO:0005764] identical protein binding [GO:0042802]; phosphatidylinositol binding [GO:0035091] 0.9397 -1.2989 QKEMESLKK 0 0 0 0 9.7292 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P57772 SELB_HUMAN "Selenocysteine-specific elongation factor (Elongation factor sec) (Eukaryotic elongation factor, selenocysteine-tRNA-specific)" EEFSEC SELB Homo sapiens (Human) selenocysteine incorporation [GO:0001514] cytoplasm [GO:0005737]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribonucleoprotein complex binding [GO:0043021]; selenocysteine insertion sequence binding [GO:0035368]; translation elongation factor activity [GO:0003746]; tRNA binding [GO:0000049] 0.56137 0.52703 DPSGPFLMSVDHCFSIK 0 0 0 9.27072 9.1274 0 0 0 0 0 9.69167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P57773 CXA9_HUMAN Gap junction alpha-9 protein (Connexin-58) (Cx58) (Connexin-59) (Cx59) (Gap junction alpha-10 protein) GJA9 GJA10 Homo sapiens (Human) cell-cell signaling [GO:0007267] connexin complex [GO:0005922] gap junction channel activity [GO:0005243] 0.96424 -2.4183 LEQELCQLEKRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0034 0 0 0 0 0 P58005 SESN3_HUMAN Sestrin-3 (EC 1.11.1.-) SESN3 SEST3 Homo sapiens (Human) cellular response to amino acid starvation [GO:0034198]; cellular response to glucose starvation [GO:0042149]; cellular response to leucine [GO:0071233]; cellular response to leucine starvation [GO:1990253]; glucose homeostasis [GO:0042593]; negative regulation of TORC1 signaling [GO:1904262]; positive regulation of macroautophagy [GO:0016239]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of protein kinase B signaling [GO:0051896]; regulation of response to reactive oxygen species [GO:1901031]; response to insulin [GO:0032868]; TORC2 signaling [GO:0038203] cytoplasm [GO:0005737]; nucleus [GO:0005634]; TORC2 complex [GO:0031932] "leucine binding [GO:0070728]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]" 0.9276 -1.1964 EDEEASQEEMSTR 0 9.8941 0 0 0 0 0 0 0 0 0 9.70714 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P58012 FOXL2_HUMAN Forkhead box protein L2 FOXL2 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; apoptotic DNA fragmentation [GO:0006309]; cell differentiation [GO:0030154]; embryonic eye morphogenesis [GO:0048048]; extraocular skeletal muscle development [GO:0002074]; female somatic sex determination [GO:0019101]; granulosa cell differentiation [GO:0060014]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oocyte growth [GO:0001555]; ovarian follicle development [GO:0001541]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of follicle-stimulating hormone secretion [GO:0046881]; positive regulation of luteinizing hormone secretion [GO:0033686]; regulation of transcription by RNA polymerase II [GO:0006357]; single fertilization [GO:0007338]; uterus development [GO:0060065] chromatin [GO:0000785]; Flemming body [GO:0090543]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "cysteine-type endopeptidase regulator activity involved in apoptotic process [GO:0043028]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; nuclear estrogen receptor binding [GO:0030331]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]; ubiquitin conjugating enzyme binding [GO:0031624]" 0.95521 -1.5623 TVKEPEGPPPSPGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.28228 0 0 0 0 0 0 0 0 0 0 P58107 EPIPL_HUMAN Epiplakin (450 kDa epidermal antigen) EPPK1 EPIPL Homo sapiens (Human) intermediate filament bundle assembly [GO:0045110]; intermediate filament organization [GO:0045109]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of wound healing [GO:0061045]; regulation of epithelium regeneration [GO:1905041]; wound healing [GO:0042060] apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; hemidesmosome [GO:0030056]; intermediate filament cytoskeleton [GO:0045111]; keratin filament [GO:0045095]; membrane [GO:0016020]; perinucleolar compartment [GO:0097356] intermediate filament binding [GO:0019215]; keratin filament binding [GO:1990254]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198] 0.96933 -3.9867 AATMEVK 8.18125 0 0 0 0 0 0 0 0 0 0 9.51912 0 10.7785 8.72584 0 10.2629 0 0 0 0 0 0 9.8867 10.0837 0 10.0649 P58215 LOXL3_HUMAN Lysyl oxidase homolog 3 (EC 1.4.3.-) (EC 1.4.3.13) (Lysyl oxidase-like protein 3) LOXL3 LOXL Homo sapiens (Human) collagen fibril organization [GO:0030199]; epithelial to mesenchymal transition [GO:0001837]; fibronectin fibril organization [GO:1905590]; inflammatory response [GO:0006954]; lung development [GO:0030324]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of T-helper 17 cell lineage commitment [GO:2000329]; peptidyl-lysine oxidation [GO:0018057]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; roof of mouth development [GO:0060021]; somite development [GO:0061053]; spinal cord development [GO:0021510] collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleus [GO:0005634] copper ion binding [GO:0005507]; fibronectin binding [GO:0001968]; protein-lysine 6-oxidase activity [GO:0004720]; scavenger receptor activity [GO:0005044] 0.75943 0.30366 ASTWGTVCDR 0 9.1982 0 0 0 0 0 0 0 0 0 0 0 0 0 11.9995 0 0 0 0 0 0 0 0 0 0 0 P58304 VSX2_HUMAN Visual system homeobox 2 (Ceh-10 homeodomain-containing homolog) (Homeobox protein CHX10) VSX2 CHX10 HOX10 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357]; response to stimulus [GO:0050896]; visual perception [GO:0007601] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.80315 0.23864 AGEALSKPK 0 0 12.2921 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P58335 ANTR2_HUMAN Anthrax toxin receptor 2 (Capillary morphogenesis gene 2 protein) (CMG-2) ANTXR2 CMG2 Homo sapiens (Human) toxin transport [GO:1901998] endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular region [GO:0005576]; plasma membrane [GO:0005886] metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888] 0.88493 -0.22786 ISKGLEDLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.97874 0 0 0 0 0 0 0 0 0 0 0 0 P58340 MLF1_HUMAN Myeloid leukemia factor 1 (Myelodysplasia-myeloid leukemia factor 1) MLF1 Homo sapiens (Human) cell cycle [GO:0007049]; DNA-templated transcription [GO:0006351]; myeloid progenitor cell differentiation [GO:0002318]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of DNA-templated transcription [GO:0006355]; regulation of signal transduction by p53 class mediator [GO:1901796] ciliary basal body [GO:0036064]; cilium [GO:0005929]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] DNA binding [GO:0003677]; protein domain specific binding [GO:0019904] 0.96198 -2.5603 IGDEPPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7.98851 0 0 0 0 0 0 0 P58397 ATS12_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 12 (ADAM-TS 12) (ADAM-TS12) (ADAMTS-12) (EC 3.4.24.-) ADAMTS12 UNQ1918/PRO4389 Homo sapiens (Human) cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to BMP stimulus [GO:0071773]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chondrocyte differentiation [GO:0002062]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; negative regulation of cellular response to hepatocyte growth factor stimulus [GO:2001113]; negative regulation of cellular response to vascular endothelial growth factor stimulus [GO:1902548]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of hepatocyte growth factor receptor signaling pathway [GO:1902203]; ossification involved in bone maturation [GO:0043931]; proteoglycan catabolic process [GO:0030167]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of endothelial tube morphogenesis [GO:1901509]; regulation of inflammatory response [GO:0050727] extracellular matrix [GO:0031012]; extracellular region [GO:0005576] metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222] 0.88869 -0.41056 EPTCGLK 11.2694 11.3213 0 0 9.31188 9.00363 10.9027 10.2019 0 0 10.2668 10.4646 0 0 9.99718 10.1555 0 9.88562 9.31388 0 9.10766 0 10.4194 10.1157 9.28313 0 0 P58417 NXPH1_HUMAN Neurexophilin-1 NXPH1 NPH1 Nbla00697 Homo sapiens (Human) extracellular region [GO:0005576] signaling receptor binding [GO:0005102] 0.84632 0.17356 LLSQTFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.74819 0 P58557 YBEY_HUMAN Endoribonuclease YbeY (EC 3.1.-.-) YBEY C21orf57 Homo sapiens (Human) rRNA processing [GO:0006364] nucleus [GO:0005634] metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; RNA endonuclease activity [GO:0004521] 0.96384 -2.1064 AVLDELGRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1989 0 0 0 0 0 0 0 0 0 0 0 P58872 RHBL3_HUMAN Rhomboid-related protein 3 (EC 3.4.21.105) (Ventrhoid transmembrane protein) RHBDL3 RHBDL4 VRHO Homo sapiens (Human) proteolysis [GO:0006508] membrane [GO:0016020] calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252] 0.91853 -0.87854 IEELEPEAEERLPAAPEDHWK 0 0 0 0 0 0 0 0 0 13.0589 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P59020 DSCR9_HUMAN Down syndrome critical region protein 9 DSCR9 Homo sapiens (Human) 0.88361 -0.10638 APPSWSRDHAYSRR 0 0 8.84599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P59025 RTP1_HUMAN Receptor-transporting protein 1 (3CxxC-type zinc finger protein 1) RTP1 Z3CXXC1 Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; protein insertion into membrane [GO:0051205]; protein targeting to membrane [GO:0006612] cell surface [GO:0009986]; plasma membrane [GO:0005886] metal ion binding [GO:0046872]; olfactory receptor binding [GO:0031849] 0.84309 0.15187 EQCYGER 0 10.3526 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P59044 NLRP6_HUMAN "NACHT, LRR and PYD domains-containing protein 6 (Angiotensin II/vasopressin receptor) (PYRIN-containing APAF1-like protein 5)" NLRP6 NALP6 PYPAF5 Homo sapiens (Human) activation of cysteine-type endopeptidase activity [GO:0097202]; acute inflammatory response [GO:0002526]; acute inflammatory response to antigenic stimulus [GO:0002438]; antiviral innate immune response [GO:0140374]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; host-mediated regulation of intestinal microbiota composition [GO:0048874]; necroptotic process [GO:0070266]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of type II interferon production [GO:0032689]; neutrophil-mediated killing of gram-positive bacterium [GO:0070946]; NLRP6 inflammasome complex assembly [GO:0140739]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-18-mediated signaling pathway [GO:2000494]; protein homooligomerization [GO:0051260]; pyroptosis [GO:0070269]; regulation of autophagy [GO:0010506]; regulation of inflammatory response [GO:0050727]; regulation of mucus secretion [GO:0070255]; response to bacterium [GO:0009617]; wound healing [GO:0042060] canonical inflammasome complex [GO:0061702]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; NLRP6 inflammasome complex [GO:0140738]; non-membrane-bounded organelle [GO:0043228]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; lipopolysaccharide binding [GO:0001530]; lipoteichoic acid binding [GO:0070891]; molecular condensate scaffold activity [GO:0140693]; molecular function activator activity [GO:0140677]; pattern recognition receptor activity [GO:0038187]; peptide binding [GO:0042277]; signaling adaptor activity [GO:0035591]; signaling receptor activator activity [GO:0030546]; vasopressin receptor activity [GO:0005000] 0.59115 0.46303 GLQYLVGMLR 0 0 0 0 0 8.59567 0 0 0 0 0 0 0 0 0 0 9.52025 0 0 0 0 0 0 0 0 0 0 P59045 NAL11_HUMAN "NACHT, LRR and PYD domains-containing protein 11 (Nucleotide-binding oligomerization domain protein 17) (PAAD-and NACHT domain-containing protein 10) (PYRIN-containing APAF1-like protein 6)" NLRP11 NALP11 NOD17 PAN10 PYPAF6 Homo sapiens (Human) regulation of inflammatory response [GO:0050727] cytoplasm [GO:0005737] "ATP binding [GO:0005524]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen [GO:0016715]; RNA binding [GO:0003723]" 0.9675 -2.9841 EIYFNSFFKDR 8.85991 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.39909 0 0 P59051 BRAS2_HUMAN Putative uncharacterized protein encoded by BRWD1-AS2 (ATP1A1 antisense RNA 1) (ATP1A1 antisense gene protein 1) (BRWD1 intronic transcript 2) BRWD1-AS2 BRWD1-IT2 C21orf87 NCRNA00257 Homo sapiens (Human) 0.95465 -1.5019 QPSAPQTLRQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.20296 0 0 0 0 0 0 P59074 CHM4P_HUMAN Putative charged multivesicular body protein 4B-like protein CHMP4BP1 (Charged multivesicular body protein 4B pseudogene 1) CHMP4BP1 CGI-301 Homo sapiens (Human) autophagosome maturation [GO:0097352]; late endosome to lysosome transport [GO:1902774]; late endosome to vacuole transport via multivesicular body sorting pathway [GO:0032511]; midbody abscission [GO:0061952]; mitotic metaphase plate congression [GO:0007080]; negative regulation of cell death [GO:0060548]; nuclear membrane reassembly [GO:0031468]; plasma membrane repair [GO:0001778]; regulation of mitotic spindle assembly [GO:1901673]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; vesicle budding from membrane [GO:0006900]; viral budding from plasma membrane [GO:0046761]; viral budding via host ESCRT complex [GO:0039702] amphisome membrane [GO:1904930]; cytoplasmic side of plasma membrane [GO:0009898]; ESCRT III complex [GO:0000815]; kinetochore [GO:0000776]; kinetochore microtubule [GO:0005828]; lysosomal membrane [GO:0005765]; midbody [GO:0030496]; multivesicular body [GO:0005771]; multivesicular body membrane [GO:0032585]; nuclear pore [GO:0005643] 0.65639 0.39526 NMGSAAK 9.45584 9.41149 9.10871 9.93926 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P59190 RAB15_HUMAN Ras-related protein Rab-15 RAB15 Homo sapiens (Human) positive regulation of regulated secretory pathway [GO:1903307]; protein transport [GO:0015031]; Rab protein signal transduction [GO:0032482] cilium [GO:0005929]; cytoplasm [GO:0005737]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.748 0.31576 LLLIGDSGVGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.049 0 0 0 0 0 0 0 0 0 P59510 ATS20_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 20 (ADAM-TS 20) (ADAM-TS20) (ADAMTS-20) (EC 3.4.24.-) ADAMTS20 Homo sapiens (Human) apoptotic process [GO:0006915]; extracellular matrix organization [GO:0030198]; melanocyte differentiation [GO:0030318]; negative regulation of apoptotic process [GO:0043066]; positive regulation of melanocyte differentiation [GO:0045636]; positive regulation of signal transduction [GO:0009967]; proteolysis [GO:0006508]; signal transduction [GO:0007165] extracellular matrix [GO:0031012]; extracellular space [GO:0005615] metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270] 0.93019 -1.235 ACRSVRCPSWK 9.10205 0 9.71917 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P59534 T2R39_HUMAN Taste receptor type 2 member 39 (T2R39) (Taste receptor type 2 member 57) (T2R57) TAS2R39 Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580] membrane [GO:0016020]; plasma membrane [GO:0005886] bitter taste receptor activity [GO:0033038]; G protein-coupled receptor activity [GO:0004930] 0.96763 -2.9602 LGRCFPPDTKEK 11.1557 0 0 0 0 0 0 0 0 0 0 0 0 0 8.54257 0 0 0 0 0 0 0 0 0 0 0 0 P59537 T2R43_HUMAN Taste receptor type 2 member 43 (T2R43) (Taste receptor type 2 member 52) (T2R52) TAS2R43 Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; G protein-coupled receptor signaling pathway [GO:0007186] ciliary membrane [GO:0060170]; membrane [GO:0016020]; motile cilium [GO:0031514]; plasma membrane [GO:0005886] bitter taste receptor activity [GO:0033038]; G protein-coupled receptor activity [GO:0004930]; taste receptor activity [GO:0008527] 0.91353 -0.75999 LKQTFLSVFWQMR 0 10.1325 0 0 0 0 0 9.67948 0 0 0 0 0 0 0 0 0 0 0 0 8.68198 0 0 0 0 0 0 P59817 Z280A_HUMAN Zinc finger protein 280A (3'OY11.1) (Suppressor of hairy wing homolog 1) (Zinc finger protein 636) ZNF280A SUHW1 ZNF280 ZNF636 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.057495 1.3736 ASESALAMTDISSLASQNKTFDPK 0 11.1249 0 0 0 0 0 0 0 0 0 0 0 9.8829 0 0 0 0 0 0 0 0 0 0 0 0 0 P59901 LIRA4_HUMAN Leukocyte immunoglobulin-like receptor subfamily A member 4 (CD85 antigen-like family member G) (Immunoglobulin-like transcript 7) (ILT-7) (CD antigen CD85g) LILRA4 ILT7 Homo sapiens (Human) cytokine-mediated signaling pathway [GO:0019221]; Fc-epsilon receptor signaling pathway [GO:0038095]; innate immune response [GO:0045087]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of toll-like receptor 7 signaling pathway [GO:0034156]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; negative regulation of tumor necrosis factor production [GO:0032720] Fc-epsilon receptor I complex [GO:0032998]; plasma membrane [GO:0005886] coreceptor activity [GO:0015026]; inhibitory MHC class I receptor activity [GO:0032396]; signaling receptor binding [GO:0005102] 0.88314 -0.2665 EGNSMSRHILK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4068 0 0 0 0 0 0 0 0 0 P59923 ZN445_HUMAN Zinc finger protein 445 (ZFP445) (Zinc finger protein 168) (Zinc finger protein with KRAB and SCAN domains 15) ZNF445 ZFP445 ZKSCAN15 ZNF168 Homo sapiens (Human) negative regulation of gene expression via CpG island methylation [GO:0044027]; regulation of genetic imprinting [GO:2000653] nucleus [GO:0005634] "chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; double-stranded methylated DNA binding [GO:0010385]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96735 -2.8491 DQCENPIQVRVKK 0 0 0 0 0 0 0 0 0 8.98581 0 0 0 0 0 0 0 0 0 0 0 8.4417 0 0 0 0 0 P59998 ARPC4_HUMAN Actin-related protein 2/3 complex subunit 4 (Arp2/3 complex 20 kDa subunit) (p20-ARC) ARPC4 ARC20 Homo sapiens (Human) actin filament polymerization [GO:0030041]; actin nucleation [GO:0045010]; Arp2/3 complex-mediated actin nucleation [GO:0034314] Arp2/3 protein complex [GO:0005885]; cell projection [GO:0042995]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; site of double-strand break [GO:0035861] actin binding [GO:0003779]; enzyme binding [GO:0019899]; structural constituent of cytoskeleton [GO:0005200] 0.14286 1.0407 AENFFILR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0199 0 P60174 TPIS_HUMAN Triosephosphate isomerase (TIM) (EC 5.3.1.1) (Methylglyoxal synthase) (EC 4.2.3.3) (Triose-phosphate isomerase) TPI1 TPI Homo sapiens (Human) canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634] methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625] 0 58.031 FFVGGNWK 8.15916 9.25708 0 0 0 0 0 8.61644 10.5476 10.397 10.3518 10.7421 11.6402 11.5491 11.394 11.9492 12.3615 11.7068 11.4264 12.0244 12.1505 11.8044 11.7768 11.8592 13.0711 12.9671 11.7752 P60228 EIF3E_HUMAN Eukaryotic translation initiation factor 3 subunit E (eIF3e) (Eukaryotic translation initiation factor 3 subunit 6) (Viral integration site protein INT-6 homolog) (eIF-3 p48) EIF3E EIF3S6 INT6 Homo sapiens (Human) "formation of cytoplasmic translation initiation complex [GO:0001732]; negative regulation of translational initiation [GO:0045947]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of mRNA binding [GO:1902416]; positive regulation of translation [GO:0045727]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413]" "cytoplasm [GO:0005737]; cytosol [GO:0005829]; eukaryotic 43S preinitiation complex [GO:0016282]; eukaryotic 48S preinitiation complex [GO:0033290]; eukaryotic translation initiation factor 3 complex [GO:0005852]; eukaryotic translation initiation factor 3 complex, eIF3e [GO:0071540]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; postsynaptic density [GO:0014069]" cadherin binding [GO:0045296]; RNA binding [GO:0003723]; translation initiation factor activity [GO:0003743] 0.96364 -2.1328 MAEYDLTTRIAHFLDR 0 0 0 0 0 0 13.9391 0 9.91713 0 0 0 10.6571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P60323 NANO3_HUMAN Nanos homolog 3 (NOS-3) NANOS3 NOS3 Homo sapiens (Human) "apoptotic signaling pathway [GO:0097190]; germ cell development [GO:0007281]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of translation [GO:0017148]; oogenesis [GO:0048477]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; regulation of cell cycle [GO:0051726]; regulation of translation [GO:0006417]; spermatogenesis [GO:0007283]" cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; perinuclear region of cytoplasm [GO:0048471] mRNA binding [GO:0003729]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270] 0.91707 -0.76643 DYVCPQCGATRER 0 0 0 0 8.94219 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P60410 KR108_HUMAN Keratin-associated protein 10-8 (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8) KRTAP10-8 KAP10.8 KAP18-8 KRTAP10.8 KRTAP18-8 KRTAP18.8 Homo sapiens (Human) cytosol [GO:0005829]; keratin filament [GO:0045095] identical protein binding [GO:0042802] 0.88297 -0.060898 TYVIAASTMSVCSSDVGHVSR 0 0 9.66686 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P60412 KR10B_HUMAN Keratin-associated protein 10-11 (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11) KRTAP10-11 KAP10.11 KAP18-11 KRTAP10.11 KRTAP18-11 KRTAP18.11 Homo sapiens (Human) cytosol [GO:0005829]; keratin filament [GO:0045095] 0.56116 0.50851 LACYSLCSGKK 0 0 0 0 0 0 0 10.6949 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P60468 SC61B_HUMAN Protein transport protein Sec61 subunit beta SEC61B Homo sapiens (Human) "post-translational protein targeting to membrane, translocation [GO:0031204]; retrograde protein transport, ER to cytosol [GO:0030970]; SRP-dependent cotranslational protein targeting to membrane, translocation [GO:0006616]; ubiquitin-dependent ERAD pathway [GO:0030433]" cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum quality control compartment [GO:0044322]; endoplasmic reticulum Sec complex [GO:0031205]; membrane [GO:0016020]; Sec61 translocon complex [GO:0005784] epidermal growth factor binding [GO:0048408]; ribosome binding [GO:0043022]; RNA binding [GO:0003723] 0.91675 -0.84543 FYTEDSPGLK 8.97582 0 0 0 9.72652 0 9.2306 0 9.25385 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P60484 PTEN_HUMAN "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Mutated in multiple advanced cancers 1) (Phosphatase and tensin homolog)" PTEN MMAC1 TEP1 Homo sapiens (Human) "apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cell migration [GO:0016477]; cell motility [GO:0048870]; cellular response to electrical stimulus [GO:0071257]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; learning or memory [GO:0007611]; localization [GO:0051179]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; multicellular organismal response to stress [GO:0033555]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cellular senescence [GO:2000773]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of cellular component size [GO:0032535]; regulation of neuron projection development [GO:0010975]; regulation of protein kinase B signaling [GO:0051896]; regulation of protein stability [GO:0031647]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]" apical plasma membrane [GO:0016324]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; myelin sheath adaxonal region [GO:0035749]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic density [GO:0014069]; Schmidt-Lanterman incisure [GO:0043220] "anaphase-promoting complex binding [GO:0010997]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [GO:0051717]; lipid binding [GO:0008289]; molecular function inhibitor activity [GO:0140678]; myosin phosphatase activity [GO:0017018]; PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [GO:0051800]; phosphatidylinositol-3-phosphate phosphatase activity [GO:0004438]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine phosphatase activity [GO:0004725]; ubiquitin-specific protease binding [GO:1990381]" 0.96944 -3.0498 GVTIPSQRR 0 0 9.37541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.827 0 0 8.45984 0 0 0 0 P60509 ERB1_HUMAN Endogenous retrovirus group PABLB member 1 Env polyprotein (Endogenous retrovirus group PABLB member 1) (Envelope polyprotein) (HERV-R(b) Env protein) (HERV-R(b)_3p24.3 provirus ancestral Env polyprotein) [Includes: Surface protein domain (SU); Transmembrane protein domain (TM)] ERVPABLB-1 Homo sapiens (Human) plasma membrane [GO:0005886] 0.56423 0.51432 NISLALEDTCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5269 0 0 0 0 0 0 0 0 P60660 MYL6_HUMAN Myosin light polypeptide 6 (17 kDa myosin light chain) (LC17) (Myosin light chain 3) (MLC-3) (Myosin light chain alkali 3) (Myosin light chain A3) (Smooth muscle and nonmuscle myosin light chain alkali 6) MYL6 Homo sapiens (Human) muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; skeletal muscle tissue development [GO:0007519] brush border [GO:0005903]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; myosin complex [GO:0016459]; myosin II complex [GO:0016460]; unconventional myosin complex [GO:0016461]; vesicle [GO:0031982] calcium ion binding [GO:0005509]; cytoskeletal motor activity [GO:0003774]; microfilament motor activity [GO:0000146]; structural constituent of muscle [GO:0008307] 0.85 0.10947 ALGQNPTNAEVLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.18269 0 0 P60827 C1QT8_HUMAN Complement C1q tumor necrosis factor-related protein 8 (C1q/TNF-related protein 8) (CTRP8) C1QTNF8 UNQ5829/PRO19648 Homo sapiens (Human) positive regulation of cell motility [GO:2000147] collagen trimer [GO:0005581]; extracellular space [GO:0005615] 0.86007 0.093255 EGPPGAR 0 0 0 0 0 0 0 0 0 13.1029 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P60842 IF4A1_HUMAN Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1) EIF4A1 DDX2A EIF4A Homo sapiens (Human) cytoplasmic translational initiation [GO:0002183]; translational initiation [GO:0006413] cytoplasm [GO:0005737]; cytosol [GO:0005829]; eukaryotic translation initiation factor 4F complex [GO:0016281]; extracellular exosome [GO:0070062]; membrane [GO:0016020] "ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; double-stranded RNA binding [GO:0003725]; helicase activity [GO:0004386]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]; RNA helicase activity [GO:0003724]; translation factor activity, RNA binding [GO:0008135]; translation initiation factor activity [GO:0003743]" 0 10.604 EELTLEGIR 9.25427 9.15901 8.94075 0 0 0 0 9.49468 10.4207 8.90665 9.15302 0 10.2491 10.0382 9.26611 8.22526 10.4472 8.93248 11.3155 10.8323 9.50303 9.25522 9.16222 9.2842 10.5796 10.2812 10.9134 P60866 RS20_HUMAN Small ribosomal subunit protein uS10 (40S ribosomal protein S20) RPS20 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; positive regulation of signal transduction by p53 class mediator [GO:1901798]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; synapse [GO:0045202] MDM2/MDM4 family protein binding [GO:0097371]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin ligase inhibitor activity [GO:1990948] 0.021127 1.6488 AFKDTGK 0 0 0 8.9009 8.9246 9.03306 0 0 0 0 0 0 8.85166 0 0 9.08821 0 0 0 0 0 0 0 0 9.65435 0 0 P60900 PSA6_HUMAN Proteasome subunit alpha type-6 (27 kDa prosomal protein) (PROS-27) (p27K) (Macropain iota chain) (Multicatalytic endopeptidase complex iota chain) (Proteasome iota chain) PSMA6 PROS27 Homo sapiens (Human) positive regulation of NF-kappaB transcription factor activity [GO:0051092]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of inflammatory response [GO:0050727] "cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; myofibril [GO:0030016]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; polysome [GO:0005844]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; sarcomere [GO:0030017]" endopeptidase activity [GO:0004175]; NF-kappaB binding [GO:0051059]; purine ribonucleoside triphosphate binding [GO:0035639]; RNA binding [GO:0003723] 0.43054 0.66073 AINQGGLTSVAVR 0 0 10.2084 0 0 0 9.45986 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P60981 DEST_HUMAN Destrin (Actin-depolymerizing factor) (ADF) DSTN ACTDP DSN Homo sapiens (Human) actin filament depolymerization [GO:0030042]; actin filament fragmentation [GO:0030043]; actin filament severing [GO:0051014]; actin polymerization or depolymerization [GO:0008154]; positive regulation of actin filament depolymerization [GO:0030836] actin cytoskeleton [GO:0015629]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062] actin filament binding [GO:0051015] 0 3.8117 ASGVQVADEVCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.91812 9.61136 9.63979 9.66359 0 8.40118 8.41574 0 10.2227 10.2164 0 P60983 GMFB_HUMAN Glia maturation factor beta (GMF-beta) GMFB Homo sapiens (Human) actin filament debranching [GO:0071846]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; nervous system development [GO:0007399]; protein phosphorylation [GO:0006468] actin binding [GO:0003779]; Arp2/3 complex binding [GO:0071933]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; protein kinase inhibitor activity [GO:0004860] 0.6848 0.38933 FIVYSYK 0 0 0 15.4655 0 15.3589 0 0 0 0 0 0 0 0 0 12.054 0 0 0 0 0 0 0 0 0 0 0 P61009 SPCS3_HUMAN Signal peptidase complex subunit 3 (Microsomal signal peptidase 22/23 kDa subunit) (SPC22/23) (SPase 22/23 kDa subunit) SPCS3 SPC22 UNQ1841/PRO3567 Homo sapiens (Human) protein targeting to ER [GO:0045047]; proteolysis [GO:0006508]; signal peptide processing [GO:0006465]; viral protein processing [GO:0019082] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; signal peptidase complex [GO:0005787] 0.96703 -3.7065 GDNPKLLLK 0 0 10.3912 0 0 11.7777 0 0 12.6779 0 12.5215 0 0 12.2764 0 0 0 0 0 0 11.0865 0 0 0 0 0 10.6641 P61011 SRP54_HUMAN Signal recognition particle subunit SRP54 (EC 3.6.5.-) (Signal recognition particle 54 kDa protein) SRP54 Homo sapiens (Human) "exocrine pancreas development [GO:0031017]; granulocyte differentiation [GO:0030851]; neutrophil chemotaxis [GO:0030593]; protein targeting to ER [GO:0045047]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition [GO:0006617]; SRP-dependent cotranslational protein targeting to membrane, translocation [GO:0006616]" "cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; signal recognition particle, endoplasmic reticulum targeting [GO:0005786]" 7S RNA binding [GO:0008312]; endoplasmic reticulum signal peptide binding [GO:0030942]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribonucleoprotein complex binding [GO:0043021]; RNA binding [GO:0003723] 0.89822 -0.66802 AGAFDQLK 0 0 0 0 0 0 0 0 0 11.2372 0 0 0 0 0 0 0 9.82139 0 0 0 0 0 0 0 0 0 P61019 RAB2A_HUMAN Ras-related protein Rab-2A (EC 3.6.5.2) RAB2A RAB2 Homo sapiens (Human) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] acrosomal vesicle [GO:0001669]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; lysosomal membrane [GO:0005765]; melanosome [GO:0042470]; nucleus [GO:0005634] GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.77282 0.27172 SITRSYYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.9893 P61026 RAB10_HUMAN Ras-related protein Rab-10 (EC 3.6.5.2) RAB10 Homo sapiens (Human) antigen processing and presentation [GO:0019882]; axonogenesis [GO:0007409]; cellular response to insulin stimulus [GO:0032869]; endoplasmic reticulum tubular network organization [GO:0071786]; endosomal transport [GO:0016197]; establishment of neuroblast polarity [GO:0045200]; establishment of protein localization to endoplasmic reticulum membrane [GO:0097051]; establishment of protein localization to membrane [GO:0090150]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi to plasma membrane transport [GO:0006893]; polarized epithelial cell differentiation [GO:0030859]; protein localization to basolateral plasma membrane [GO:1903361]; protein localization to plasma membrane [GO:0072659]; regulated exocytosis [GO:0045055]; vesicle-mediated transport [GO:0016192] adherens junction [GO:0005912]; cilium [GO:0005929]; cytoplasmic vesicle membrane [GO:0030659]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum tubular network [GO:0071782]; endosome [GO:0005768]; exocytic vesicle [GO:0070382]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; insulin-responsive compartment [GO:0032593]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802] cadherin binding involved in cell-cell adhesion [GO:0098641]; G protein activity [GO:0003925]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; myosin V binding [GO:0031489] 0.81352 0.22155 LLLIGDSGVGK 0 0 0 9.0758 8.98897 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P61077 UB2D3_HUMAN Ubiquitin-conjugating enzyme E2 D3 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D3) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D3) (Ubiquitin carrier protein D3) (Ubiquitin-conjugating enzyme E2(17)KB 3) (Ubiquitin-conjugating enzyme E2-17 kDa 3) (Ubiquitin-protein ligase D3) UBE2D3 UBC5C UBCH5C Homo sapiens (Human) apoptotic process [GO:0006915]; DNA repair [GO:0006281]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of protein targeting to mitochondrion [GO:1903955]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein modification process [GO:0036211]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] cytosol [GO:0005829]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ubiquitin ligase complex [GO:0000151] ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842] 0.88014 0.014835 ISREWTQK 0 0 0 0 0 0 8.87958 0 10.4667 0 0 9.2502 0 0 0 0 0 0 0 10.0334 9.03188 0 0 0 0 0 0 P61129 ZC3H6_HUMAN Zinc finger CCCH domain-containing protein 6 ZC3H6 KIAA2035 ZC3HDC6 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; RNA metabolic process [GO:0016070] chromatin [GO:0000785]; nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA binding [GO:0003723] 0.84264 0.15114 SNPGSSQPSGAGTSNSGSGALPPYAPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1904 0 0 0 0 0 0 P61158 ARP3_HUMAN Actin-related protein 3 (Actin-like protein 3) ACTR3 ARP3 Homo sapiens (Human) actin polymerization-dependent cell motility [GO:0070358]; Arp2/3 complex-mediated actin nucleation [GO:0034314]; asymmetric cell division [GO:0008356]; cellular response to type II interferon [GO:0071346]; cilium assembly [GO:0060271]; establishment or maintenance of cell polarity [GO:0007163]; meiotic chromosome movement towards spindle pole [GO:0016344]; meiotic cytokinesis [GO:0033206]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of transcription by RNA polymerase II [GO:0045944]; spindle localization [GO:0051653] actin cytoskeleton [GO:0015629]; Arp2/3 protein complex [GO:0005885]; brush border [GO:0005903]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; membrane [GO:0016020]; nucleus [GO:0005634]; site of double-strand break [GO:0035861] actin binding [GO:0003779]; ATP binding [GO:0005524]; structural constituent of cytoskeleton [GO:0005200] 0.96025 -1.797 LKLSEELSGGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.49939 0 0 9.67996 0 0 0 10.4726 9.24909 10.4748 P61201 CSN2_HUMAN COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15) COPS2 CSN2 TRIP15 Homo sapiens (Human) inner cell mass cell proliferation [GO:0001833]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; protein deneddylation [GO:0000338]; protein neddylation [GO:0045116]; protein phosphorylation [GO:0006468]; regulation of protein neddylation [GO:2000434]; signal transduction [GO:0007165]; skeletal muscle cell differentiation [GO:0035914]; transcription by RNA polymerase II [GO:0006366]; trophectodermal cell proliferation [GO:0001834] COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] transcription corepressor activity [GO:0003714] 0.95296 -1.4803 ALKEDDPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.48844 0 0 0 0 0 0 0 0 P61221 ABCE1_HUMAN ATP-binding cassette sub-family E member 1 (EC 3.6.5.-) (2'-5'-oligoadenylate-binding protein) (HuHP68) (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I) ABCE1 RLI RNASEL1 RNASELI RNS4I OK/SW-cl.40 Homo sapiens (Human) negative regulation of endoribonuclease activity [GO:0060702]; regulation of translation [GO:0006417]; rescue of stalled ribosome [GO:0072344]; ribosomal subunit export from nucleus [GO:0000054]; ribosome disassembly [GO:0032790]; translational initiation [GO:0006413]; translational termination [GO:0006415] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] "4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; CTPase activity [GO:0043273]; endoribonuclease inhibitor activity [GO:0060698]; GTPase activity [GO:0003924]; iron ion binding [GO:0005506]; ribonucleoside triphosphate phosphatase activity [GO:0017111]; ribosomal small subunit binding [GO:0043024]" 0.89851 -0.62148 FACAVVCIQK 0 0 0 0 0 0 0 0 0 9.02896 0 0 0 0 0 0 0 10.0168 0 0 9.89807 0 0 0 0 0 0 P61224 RAP1B_HUMAN Ras-related protein Rap-1b (EC 3.6.5.2) (GTP-binding protein smg p21B) RAP1B OK/SW-cl.11 Homo sapiens (Human) calcium-ion regulated exocytosis [GO:0017156]; cell population proliferation [GO:0008283]; cellular response to cAMP [GO:0071320]; establishment of endothelial barrier [GO:0061028]; establishment of localization in cell [GO:0051649]; modification of postsynaptic structure [GO:0099010]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of synaptic vesicle exocytosis [GO:2000301]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of integrin activation [GO:0033625]; Rap protein signal transduction [GO:0032486]; regulation of cell junction assembly [GO:1901888]; regulation of establishment of cell polarity [GO:2000114] azurophil granule membrane [GO:0035577]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; lipid droplet [GO:0005811]; membrane [GO:0016020]; plasma membrane [GO:0005886] G protein activity [GO:0003925]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein-containing complex binding [GO:0044877] 0.91894 -0.8929 CDLEDERVVGK 0 0 0 9.79375 0 0 0 8.22776 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P61244 MAX_HUMAN Protein max (Class D basic helix-loop-helix protein 4) (bHLHd4) (Myc-associated factor X) MAX BHLHD4 Homo sapiens (Human) cellular response to peptide hormone stimulus [GO:0071375]; cellular response to starvation [GO:0009267]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron apoptotic process [GO:0051402]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein-containing complex assembly [GO:0065003]; regulation of transcription by RNA polymerase II [GO:0006357]; response to axon injury [GO:0048678]; response to insulin [GO:0032868]; retina development in camera-type eye [GO:0060041] chromatin [GO:0000785]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Mad-Max complex [GO:0070443]; MLL1 complex [GO:0071339]; Myc-Max complex [GO:0071943]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription regulator complex [GO:0090575] "DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription factor binding [GO:0140297]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; E-box binding [GO:0070888]; identical protein binding [GO:0042802]; nucleic acid binding [GO:0003676]; protein dimerization activity [GO:0046983]; protein-containing complex binding [GO:0044877]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.18384 0.95029 ATEYIQYMRR 0 0 8.42488 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.76255 0 P61247 RS3A_HUMAN Small ribosomal subunit protein eS1 (40S ribosomal protein S3a) (v-fos transformation effector protein) (Fte-1) RPS3A FTE1 MFTL Homo sapiens (Human) cell differentiation [GO:0030154]; cytoplasmic translation [GO:0002181]; negative regulation of apoptotic process [GO:0043066]; ribosomal small subunit biogenesis [GO:0042274]; translation [GO:0006412]; translational initiation [GO:0006413] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; small-subunit processome [GO:0032040]; synapse [GO:0045202] mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0 5.7757 ADGYEPPVQESV 0 0 9.65789 0 0 0 9.70852 0 9.80297 0 0 9.10058 0 0 10.7576 0 0 0 0 9.62708 0 0 0 0 10.1619 10.0314 9.9516 P61266 STX1B_HUMAN Syntaxin-1B (Syntaxin-1B1) (Syntaxin-1B2) STX1B STX1B1 STX1B2 Homo sapiens (Human) calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; exocytic insertion of neurotransmitter receptor to postsynaptic membrane [GO:0098967]; intracellular protein transport [GO:0006886]; negative regulation of macropinocytosis [GO:1905302]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic vesicle recycling [GO:1903422]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neurotransmitter secretion [GO:0001956]; positive regulation of spontaneous neurotransmitter secretion [GO:1904050]; regulation of gene expression [GO:0010468]; regulation of synaptic activity [GO:0060025]; regulation of synaptic vesicle priming [GO:0010807]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle docking [GO:0016081]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; vesicle docking [GO:0048278]; vesicle docking involved in exocytosis [GO:0006904]; vesicle fusion [GO:0006906] axon [GO:0030424]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; neuromuscular junction [GO:0031594]; nuclear lamina [GO:0005652]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; SNARE complex [GO:0031201]; spindle [GO:0005819] protein kinase binding [GO:0019901]; signaling receptor binding [GO:0005102]; SNAP receptor activity [GO:0005484]; SNARE binding [GO:0000149] 0.93195 -1.2664 LKAIEQSIEQEEGLNR 0 0 11.4225 0 0 0 0 0 0 0 0 11.4998 0 0 10.6719 0 0 0 0 0 0 0 0 0 0 0 0 P61289 PSME3_HUMAN Proteasome activator complex subunit 3 (11S regulator complex subunit gamma) (REG-gamma) (Activator of multicatalytic protease subunit 3) (Ki nuclear autoantigen) (Proteasome activator 28 subunit gamma) (PA28g) (PA28gamma) PSME3 Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of endopeptidase activity [GO:0010950]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of proteasomal protein catabolic process [GO:0061136] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome activator complex [GO:0008537]; proteasome complex [GO:0000502] endopeptidase activator activity [GO:0061133]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; p53 binding [GO:0002039] 0.90616 -0.72581 IKRPRSSNAETLY 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.91097 9.02004 9.40569 9.32746 0 8.98262 0 0 0 P61313 RL15_HUMAN Large ribosomal subunit protein eL15 (60S ribosomal protein L15) RPL15 EC45 TCBAP0781 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; response to ethanol [GO:0045471]; translation [GO:0006412] A band [GO:0031672]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; nucleus [GO:0005634]; ribosome [GO:0005840]; synapse [GO:0045202] cadherin binding [GO:0045296]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0 3.0431 SLQSVAEER 9.46883 9.48039 9.22622 0 0 0 9.81333 9.90944 9.92887 0 10.1749 0 0 0 0 0 0 0 9.17901 0 0 0 8.72686 0 10.6876 11.2024 10.2342 P61353 RL27_HUMAN Large ribosomal subunit protein eL27 (60S ribosomal protein L27) RPL27 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; response to aldosterone [GO:1904044]; rRNA processing [GO:0006364]; translation [GO:0006412] cytoplasm [GO:0005737]; cytoplasmic side of rough endoplasmic reticulum membrane [GO:0098556]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; ribosome [GO:0005840]; synapse [GO:0045202] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.10674 1.1619 YSVDIPLDK 0 0 0 0 0 0 0 9.32576 9.60676 0 0 0 10.739 10.3387 0 0 0 0 0 11.4598 10.936 0 10.3741 0 0 10.9299 0 P61366 OSTN_HUMAN Osteocrin (Musclin) [Cleaved into: Processed Osteocrin] OSTN Homo sapiens (Human) cell differentiation [GO:0030154]; cell surface receptor signaling pathway [GO:0007166]; endochondral bone growth [GO:0003416]; hormone-mediated signaling pathway [GO:0009755]; negative regulation of dendrite extension [GO:1903860]; negative regulation of glucose import [GO:0046325]; negative regulation of osteoblast differentiation [GO:0045668] extracellular space [GO:0005615] hormone activity [GO:0005179]; signaling receptor binding [GO:0005102] 0.70203 0.37284 FGIPMDRIGRNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.441 0 0 P61457 PHS_HUMAN Pterin-4-alpha-carbinolamine dehydratase (PHS) (EC 4.2.1.96) (4-alpha-hydroxy-tetrahydropterin dehydratase) (Dimerization cofactor of hepatocyte nuclear factor 1-alpha) (DCoH) (Dimerization cofactor of HNF1) (Phenylalanine hydroxylase-stimulating protein) (Pterin carbinolamine dehydratase) (PCD) PCBD1 DCOH PCBD Homo sapiens (Human) tetrahydrobiopterin biosynthetic process [GO:0006729] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654] 4-alpha-hydroxytetrahydrobiopterin dehydratase activity [GO:0008124]; identical protein binding [GO:0042802]; phenylalanine 4-monooxygenase activity [GO:0004505]; transcription coactivator activity [GO:0003713] 0.93202 -1.2743 AGKAHRLSAEER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.33316 0 0 0 0 0 P61513 RL37A_HUMAN Large ribosomal subunit protein eL43 (60S ribosomal protein L37a) RPL37A Homo sapiens (Human) cytoplasmic translation [GO:0002181]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; synapse [GO:0045202] metal ion binding [GO:0046872]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.94731 -1.3546 VGIVGKYGTRYGASLR 0 0 0 0 0 0 0 0 0 14.0045 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P61576 REC04_HUMAN Endogenous retrovirus group K member 104 Rec protein (HERV-K104 Rec protein) (HERV-K_5q13.3 provirus Rec protein) HERV-K104 Homo sapiens (Human) mRNA transport [GO:0051028] cytoplasm [GO:0005737]; nucleolus [GO:0005730] RNA binding [GO:0003723] 0.91019 -0.74642 MNKMVTSEEEMK 0 9.59375 0 0 0 0 0 0 0 0 9.83879 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P61582 NP7_HUMAN Endogenous retrovirus group K member 7 Np9 protein (HERV-K(III) Np9 protein) (HERV-K102 Np9 protein) (HERV-K_1q22 provirus Np9 protein) ERVK-7 Homo sapiens (Human) nucleus [GO:0005634] 0.52381 0.58682 MNPLEMQRK 0 0 0 0 0 0 0 0 0 0 0 8.59854 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P61587 RND3_HUMAN Rho-related GTP-binding protein RhoE (Protein MemB) (Rho family GTPase 3) (Rho-related GTP-binding protein Rho8) (Rnd3) RND3 ARHE RHO8 RHOE Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; small GTPase mediated signal transduction [GO:0007264] cytoplasm [GO:0005737]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886] GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.91378 -0.75781 LSSKSIMDPNQNVK 0 0 0 0 0 0 0 0 0 14.0555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P61599 NAA20_HUMAN N-alpha-acetyltransferase 20 (EC 2.3.1.254) (Methionine N-acetyltransferase) (N-acetyltransferase 5) (N-terminal acetyltransferase B complex catalytic subunit NAA20) (N-terminal acetyltransferase B complex catalytic subunit NAT5) (NatB complex subunit NAT5) (NatB catalytic subunit) NAA20 NAT5 Homo sapiens (Human) N-terminal peptidyl-aspartic acid acetylation [GO:0017190]; N-terminal peptidyl-glutamic acid acetylation [GO:0018002]; N-terminal peptidyl-glutamine acetylation [GO:0017192]; N-terminal peptidyl-methionine acetylation [GO:0017196]; N-terminal protein amino acid acetylation [GO:0006474] cytoplasm [GO:0005737]; cytosol [GO:0005829]; NatB complex [GO:0031416]; nucleus [GO:0005634] peptide alpha-N-acetyltransferase activity [GO:0004596] 0.93011 -1.2366 KALSRDTEK 0 0 0 0 0 0 0 9.0354 8.5509 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P61601 NCALD_HUMAN Neurocalcin-delta NCALD Homo sapiens (Human) calcium-mediated signaling [GO:0019722]; regulation of systemic arterial blood pressure [GO:0003073]; vesicle-mediated transport [GO:0016192] clathrin coat of trans-Golgi network vesicle [GO:0030130]; cytosol [GO:0005829] actin binding [GO:0003779]; alpha-tubulin binding [GO:0043014]; calcium ion binding [GO:0005509]; clathrin binding [GO:0030276]; tubulin binding [GO:0015631] 0.41537 0.68466 KIYGNFFPYGDASK 0 0 0 0 0 0 0 10.7502 10.7482 0 0 11.0006 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P61604 CH10_HUMAN "10 kDa heat shock protein, mitochondrial (Hsp10) (10 kDa chaperonin) (Chaperonin 10) (CPN10) (Early-pregnancy factor) (EPF)" HSPE1 Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; chaperone cofactor-dependent protein refolding [GO:0051085]; osteoblast differentiation [GO:0001649]; protein folding [GO:0006457]; response to unfolded protein [GO:0006986] extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein folding chaperone [GO:0044183]; protein-folding chaperone binding [GO:0051087]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082] 0 25.771 AGQAFRK 11.6612 11.7087 11.7184 0 0 0 11.8919 11.9546 10.5444 10.8507 10.0105 10.1572 0 0 0 0 0 0 0 0 0 0 0 10.3375 0 10.4754 10.8574 P61619 S61A1_HUMAN Protein transport protein Sec61 subunit alpha isoform 1 (Sec61 alpha-1) SEC61A1 SEC61A Homo sapiens (Human) "cotranslational protein targeting to membrane [GO:0006613]; endoplasmic reticulum organization [GO:0007029]; post-translational protein targeting to endoplasmic reticulum membrane [GO:0006620]; post-translational protein targeting to membrane, translocation [GO:0031204]; pronephric nephron development [GO:0039019]; protein insertion into ER membrane [GO:0045048]; protein targeting to ER [GO:0045047]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; SRP-dependent cotranslational protein targeting to membrane, translocation [GO:0006616]" endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; Sec61 translocon complex [GO:0005784] calcium channel activity [GO:0005262]; protein transmembrane transporter activity [GO:0008320]; ribosome binding [GO:0043022]; signal sequence binding [GO:0005048] 0 2.9862 EQQMVMRGHR 0 0 0 0 0 0 0 0 0 11.0128 0 0 0 0 0 0 0 0 10.9367 0 0 0 0 0 0 11.3677 0 P61758 PFD3_HUMAN Prefoldin subunit 3 (HIBBJ46) (von Hippel-Lindau-binding protein 1) (VBP-1) (VHL-binding protein 1) VBP1 PFDN3 Homo sapiens (Human) microtubule-based process [GO:0007017]; negative regulation of amyloid fibril formation [GO:1905907]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; tubulin complex assembly [GO:0007021] cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; polysome [GO:0005844]; prefoldin complex [GO:0016272] amyloid-beta binding [GO:0001540]; tubulin binding [GO:0015631]; unfolded protein binding [GO:0051082] 0.92537 -0.9834 LDEQYQKYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.69839 0 0 0 0 0 P61803 DAD1_HUMAN Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (Oligosaccharyl transferase subunit DAD1) (Defender against cell death 1) (DAD-1) DAD1 Homo sapiens (Human) apoptotic process [GO:0006915]; blastocyst development [GO:0001824]; negative regulation of apoptotic process [GO:0043066]; protein glycosylation [GO:0006486]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]; regulation of protein stability [GO:0031647]; response to nutrient [GO:0007584]; response to xenobiotic stimulus [GO:0009410] endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; oligosaccharyltransferase complex [GO:0008250] enzyme activator activity [GO:0008047] 0.612 0.41913 FLEEYLSSTPQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7699 P61812 TGFB2_HUMAN Transforming growth factor beta-2 proprotein (Cetermin) (Glioblastoma-derived T-cell suppressor factor) (G-TSF) [Cleaved into: Latency-associated peptide (LAP); Transforming growth factor beta-2 (TGF-beta-2)] TGFB2 Homo sapiens (Human) activation of protein kinase activity [GO:0032147]; ascending aorta morphogenesis [GO:0035910]; atrial septum morphogenesis [GO:0060413]; atrial septum primum morphogenesis [GO:0003289]; atrioventricular valve morphogenesis [GO:0003181]; BMP signaling pathway [GO:0030509]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac muscle cell proliferation [GO:0060038]; cardiac right ventricle morphogenesis [GO:0003215]; cardioblast differentiation [GO:0010002]; cell migration [GO:0016477]; cell morphogenesis [GO:0000902]; cell-cell junction organization [GO:0045216]; collagen fibril organization [GO:0030199]; cranial skeletal system development [GO:1904888]; dopamine biosynthetic process [GO:0042416]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic digestive tract development [GO:0048566]; embryonic limb morphogenesis [GO:0030326]; endocardial cushion fusion [GO:0003274]; endocardial cushion morphogenesis [GO:0003203]; epithelial to mesenchymal transition [GO:0001837]; extrinsic apoptotic signaling pathway [GO:0097191]; eye development [GO:0001654]; generation of neurons [GO:0048699]; glial cell migration [GO:0008347]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; heart valve morphogenesis [GO:0003179]; hemopoiesis [GO:0030097]; inner ear development [GO:0048839]; kidney development [GO:0001822]; male gonad development [GO:0008584]; membranous septum morphogenesis [GO:0003149]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation [GO:1905006]; negative regulation of gene expression [GO:0010629]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of Ras protein signal transduction [GO:0046580]; neural retina development [GO:0003407]; neural tube closure [GO:0001843]; neuron development [GO:0048666]; neutrophil chemotaxis [GO:0030593]; odontogenesis [GO:0042476]; outflow tract septum morphogenesis [GO:0003148]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; pharyngeal arch artery morphogenesis [GO:0061626]; positive regulation of cardioblast differentiation [GO:0051891]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation [GO:1905007]; positive regulation of heart contraction [GO:0045823]; positive regulation of immune response [GO:0050778]; positive regulation of integrin biosynthetic process [GO:0045726]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein secretion [GO:0050714]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of timing of catagen [GO:0051795]; protein phosphorylation [GO:0006468]; pulmonary valve morphogenesis [GO:0003184]; regulation of apoptotic process involved in outflow tract morphogenesis [GO:1902256]; regulation of cell population proliferation [GO:0042127]; regulation of timing of catagen [GO:0051794]; regulation of transforming growth factor beta2 production [GO:0032909]; response to hypoxia [GO:0001666]; response to progesterone [GO:0032570]; response to wounding [GO:0009611]; response to xenobiotic stimulus [GO:0009410]; salivary gland morphogenesis [GO:0007435]; secondary palate development [GO:0062009]; signaling [GO:0023052]; skeletal system development [GO:0001501]; SMAD protein signal transduction [GO:0060395]; somatic stem cell division [GO:0048103]; substantia propria of cornea development [GO:1903701]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterine wall breakdown [GO:0042704]; uterus development [GO:0060065]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]; wound healing [GO:0042060] axon [GO:0030424]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; platelet alpha granule lumen [GO:0031093]; transforming growth factor beta complex [GO:0099126]; transforming growth factor beta ligand-receptor complex [GO:0070021] amyloid-beta binding [GO:0001540]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; transforming growth factor beta receptor binding [GO:0005160]; type II transforming growth factor beta receptor binding [GO:0005114]; type III transforming growth factor beta receptor binding [GO:0034714] 0.9408 -1.331 AAACERERSDEEYYAK 0 0 0 9.17812 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P61923 COPZ1_HUMAN Coatomer subunit zeta-1 (Zeta-1-coat protein) (Zeta-1 COP) COPZ1 COPZ CGI-120 HSPC181 Homo sapiens (Human) "intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; toxin transport [GO:1901998]" COPI vesicle coat [GO:0030126]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; transport vesicle [GO:0030133] 0.26816 0.84704 EQKAFEKNIFNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.37619 0 P61962 DCAF7_HUMAN DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog) DCAF7 HAN11 WDR68 Homo sapiens (Human) protein ubiquitination [GO:0016567] Cul4-RING E3 ubiquitin ligase complex [GO:0080008]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] protein-macromolecule adaptor activity [GO:0030674] 0.88478 -0.22207 EVYDIAFSR 9.46952 0 0 0 10.6469 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P61966 AP1S1_HUMAN AP-1 complex subunit sigma-1A (Adaptor protein complex AP-1 subunit sigma-1A) (Adaptor-related protein complex 1 subunit sigma-1A) (Clathrin assembly protein complex 1 sigma-1A small chain) (Clathrin coat assembly protein AP19) (Golgi adaptor HA1/AP1 adaptin sigma-1A subunit) (HA1 19 kDa subunit) (Sigma 1a subunit of AP-1 clathrin) (Sigma-adaptin 1A) (Sigma1A-adaptin) AP1S1 AP19 CLAPS1 Homo sapiens (Human) basolateral protein secretion [GO:0110010]; intracellular protein transport [GO:0006886]; melanosome assembly [GO:1903232]; platelet dense granule organization [GO:0060155]; receptor-mediated endocytosis [GO:0006898]; response to virus [GO:0009615]; vesicle-mediated transport [GO:0016192] AP-1 adaptor complex [GO:0030121]; clathrin-coated pit [GO:0005905]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; early endosome [GO:0005769]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; trans-Golgi network membrane [GO:0032588] clathrin adaptor activity [GO:0035615] 0.56209 0.50852 ELMQVVLAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.97062 0 0 0 0 0 0 0 0 0 P61970 NTF2_HUMAN Nuclear transport factor 2 (NTF-2) (Placental protein 15) (PP15) NUTF2 NTF2 Homo sapiens (Human) mRNA transport [GO:0051028]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654] identical protein binding [GO:0042802]; small GTPase binding [GO:0031267]; structural constituent of nuclear pore [GO:0017056] 0.021077 1.6439 LSSLPFQK 0 0 0 0 0 0 0 0 0 0 9.307 0 0 0 0 10.0084 10.1764 9.87351 0 0 0 0 0 0 0 0 0 P61978 HNRPK_HUMAN Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP) HNRNPK HNRPK Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of low-density lipoprotein receptor activity [GO:1905599]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902165]; regulation of low-density lipoprotein particle clearance [GO:0010988]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA processing [GO:0006396]; signal transduction [GO:0007165]" catalytic step 2 spliceosome [GO:0071013]; cell projection [GO:0042995]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; podosome [GO:0002102]; ribonucleoprotein complex [GO:1990904] cadherin binding [GO:0045296]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723] 0 14.431 DLAGSIIGK 8.36243 8.28188 8.37599 0 0 0 9.09299 10.4115 10.4005 8.45199 9.2401 8.48985 0 9.98726 0 0 9.09109 0 0 0 0 8.96382 0 0 11.6156 11.7663 9.43536 P61981 1433G_HUMAN "14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]" YWHAG Homo sapiens (Human) cellular response to insulin stimulus [GO:0032869]; negative regulation of protein kinase activity [GO:0006469]; protein targeting [GO:0006605]; regulation of neuron differentiation [GO:0045664]; regulation of signal transduction [GO:0009966]; regulation of synaptic plasticity [GO:0048167]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; presynapse [GO:0098793] identical protein binding [GO:0042802]; insulin-like growth factor receptor binding [GO:0005159]; protein domain specific binding [GO:0019904]; protein kinase C binding [GO:0005080]; protein kinase C inhibitor activity [GO:0008426]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723] 0 13.015 AYSEAHEISK 8.83397 0 9.01823 0 0 0 8.78807 0 0 0 0 8.44559 0 0 0 0 0 0 0 0 9.88387 0 9.98527 0 0 0 0 P62070 RRAS2_HUMAN Ras-related protein R-Ras2 (EC 3.6.5.-) (Ras-like protein TC21) (Teratocarcinoma oncogene) RRAS2 TC21 Homo sapiens (Human) osteoblast differentiation [GO:0001649]; positive regulation of Schwann cell migration [GO:1900149]; Ras protein signal transduction [GO:0007265]; Schwann cell migration [GO:0036135] endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; plasma membrane [GO:0005886] GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.86175 0.097412 ADLDHQRQVTQEEGQQLAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.91921 0 0 P62081 RS7_HUMAN Small ribosomal subunit protein eS7 (40S ribosomal protein S7) RPS7 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; negative regulation of ubiquitin protein ligase activity [GO:1904667]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; neural crest cell differentiation [GO:0014033]; neural tube closure [GO:0001843]; positive regulation of gene expression [GO:0010628]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; protein stabilization [GO:0050821]; ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; focal adhesion [GO:0005925]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; ribosome [GO:0005840]; small-subunit processome [GO:0032040]; synapse [GO:0045202] mRNA 3'-UTR binding [GO:0003730]; mRNA 5'-UTR binding [GO:0048027]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin ligase inhibitor activity [GO:1990948] 0.035011 1.5204 EIEVGGGR 0 0 0 0 0 0 0 9.28026 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P62136 PP1A_HUMAN Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16) PPP1CA PPP1A Homo sapiens (Human) beta-catenin destruction complex disassembly [GO:1904886]; branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; dephosphorylation [GO:0016311]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; lung development [GO:0030324]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to lead ion [GO:0010288] adherens junction [GO:0005912]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; glycogen granule [GO:0042587]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; PTW/PP1 phosphatase complex [GO:0072357] cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; myosin phosphatase activity [GO:0017018]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; ribonucleoprotein complex binding [GO:0043021] 0.84106 0.14313 IKYPENFFLLR 14.8055 14.8776 14.0955 13.3424 13.1371 12.9436 12.1701 12.5814 12.6347 11.6774 0 10.8786 10.1876 10.2098 0 11.1624 10.6202 9.74364 0 9.52284 9.60529 0 0 9.72521 9.78927 0 9.60578 P62140 PP1B_HUMAN Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53) PPP1CB Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; MAPK cascade [GO:0000165]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of circadian rhythm [GO:0042752] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PTW/PP1 phosphatase complex [GO:0072357] metal ion binding [GO:0046872]; myosin phosphatase activity [GO:0017018]; myosin-light-chain-phosphatase activity [GO:0050115]; phosphatase activity [GO:0016791]; protein kinase binding [GO:0019901]; protein serine/threonine phosphatase activity [GO:0004722] 0.7941 0.24498 IKYPENFFLLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9391 0 0 P62166 NCS1_HUMAN Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog) (Frequenin-like protein) (Frequenin-like ubiquitous protein) NCS1 FLUP FREQ Homo sapiens (Human) regulation of neuron projection development [GO:0010975] axon [GO:0030424]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] calcium ion binding [GO:0005509]; calcium sensitive guanylate cyclase activator activity [GO:0008048]; voltage-gated calcium channel activity [GO:0005245] 0.77183 0.26976 LTLQEFQEGSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.59908 0 0 9.80797 0 9.82173 0 P62241 RS8_HUMAN Small ribosomal subunit protein eS8 (40S ribosomal protein S8) RPS8 OK/SW-cl.83 Homo sapiens (Human) "cytoplasmic translation [GO:0002181]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosomal small subunit biogenesis [GO:0042274]; translation [GO:0006412]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; small-subunit processome [GO:0032040] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0 10.948 GISRDNWHK 0 0 0 0 0 0 0 0 8.5547 0 0 0 0 0 9.17876 0 0 0 0 0 9.4551 0 0 0 12.6855 12.2328 11.1704 P62249 RS16_HUMAN Small ribosomal subunit protein uS9 (40S ribosomal protein S16) RPS16 Homo sapiens (Human) "cellular response to leukemia inhibitory factor [GO:1990830]; cytoplasmic translation [GO:0002181]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364]; translation [GO:0006412]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small ribosomal subunit [GO:0015935]; small-subunit processome [GO:0032040]; synapse [GO:0045202] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0 5.7288 ALVAYYQK 0 0 10.2293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.06856 12.3832 11.4323 0 P62258 1433E_HUMAN 14-3-3 protein epsilon (14-3-3E) YWHAE Homo sapiens (Human) cellular response to heat [GO:0034605]; cerebral cortex development [GO:0021987]; hippocampus development [GO:0021766]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; membrane repolarization during cardiac muscle cell action potential [GO:0086013]; negative regulation of calcium ion export across plasma membrane [GO:1905913]; negative regulation of calcium ion transmembrane transporter activity [GO:1901020]; negative regulation of peptidyl-serine dephosphorylation [GO:1902309]; neuron migration [GO:0001764]; positive regulation of protein export from nucleus [GO:0046827]; protein localization to nucleus [GO:0034504]; protein targeting [GO:0006605]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of heart rate by hormone [GO:0003064]; regulation of membrane repolarization [GO:0060306]; regulation of mitotic cell cycle [GO:0007346]; regulation of potassium ion transmembrane transporter activity [GO:1901016]; signal transduction [GO:0007165]; substantia nigra development [GO:0021762] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleus [GO:0005634] cadherin binding [GO:0045296]; calcium channel regulator activity [GO:0005246]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; potassium channel regulator activity [GO:0015459]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; transmembrane transporter binding [GO:0044325]; ubiquitin protein ligase binding [GO:0031625] 0 12.947 AASDIAMTELPPTHPIR 0 0 0 0 0 0 10.2803 9.53648 9.66982 10.4226 11.1358 11.225 0 0 9.64767 0 9.92945 0 11.5606 10.7659 9.83889 0 9.15515 9.1442 11.1176 11.1516 12.2505 P62263 RS14_HUMAN Small ribosomal subunit protein uS11 (40S ribosomal protein S14) RPS14 PRO2640 Homo sapiens (Human) "cytoplasmic translation [GO:0002181]; erythrocyte differentiation [GO:0030218]; maturation of SSU-rRNA [GO:0030490]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ribosomal small subunit assembly [GO:0000028]; ribosomal small subunit biogenesis [GO:0042274]; translation [GO:0006412]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; postsynaptic density [GO:0014069]; small-subunit processome [GO:0032040] mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; small ribosomal subunit rRNA binding [GO:0070181]; structural constituent of ribosome [GO:0003735]; translation regulator activity [GO:0045182] 0 8.2989 IEDVTPIPSDSTR 10.7117 0 10.0459 0 0 0 10.714 10.6899 10.6785 0 0 9.66841 0 0 0 0 9.21522 0 0 0 9.95857 0 0 0 0 9.40401 11.1142 P62266 RS23_HUMAN Small ribosomal subunit protein uS12 (40S ribosomal protein S23) RPS23 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; maintenance of translational fidelity [GO:1990145]; ribosomal small subunit biogenesis [GO:0042274]; stress granule assembly [GO:0034063]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; endoplasmic reticulum [GO:0005783]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; polysomal ribosome [GO:0042788]; ribosome [GO:0005840]; rough endoplasmic reticulum [GO:0005791]; small-subunit processome [GO:0032040] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0 3.7055 ANPFGGASHAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.06571 8.67497 0 0 9.26177 0 0 0 0 0 9.52372 9.37571 0 P62269 RS18_HUMAN Small ribosomal subunit protein uS13 (40S ribosomal protein S18) (Ke-3) (Ke3) RPS18 D6S218E Homo sapiens (Human) cytoplasmic translation [GO:0002181]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; ribosome [GO:0005840]; small ribosomal subunit [GO:0015935] RNA binding [GO:0003723]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735] 0 5.8736 AGELTEDEVER 9.26416 10.2488 9.44257 0 0 0 10.6223 11.2269 11.0137 0 0 0 9.40712 0 9.47847 0 10.7086 10.0469 10.3045 9.41494 10.794 0 0 8.90998 9.3797 9.2817 9.27843 P62277 RS13_HUMAN Small ribosomal subunit protein uS15 (40S ribosomal protein S13) RPS13 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; negative regulation of RNA splicing [GO:0033119]; ribosomal small subunit biogenesis [GO:0042274]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; ribosome [GO:0005840]; small-subunit processome [GO:0032040] mRNA 5'-UTR binding [GO:0048027]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; small ribosomal subunit rRNA binding [GO:0070181]; structural constituent of ribosome [GO:0003735] 0 7.3306 GLSQSALPYR 0 0 0 0 0 0 8.99997 0 0 9.15543 0 0 0 0 0 0 0 0 0 0 0 0 0 9.95641 10.4278 10.3293 8.45648 P62280 RS11_HUMAN Small ribosomal subunit protein uS17 (40S ribosomal protein S11) RPS11 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; ribosomal small subunit biogenesis [GO:0042274]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; ribosome [GO:0005840]; small-subunit processome [GO:0032040]; synapse [GO:0045202] RNA binding [GO:0003723]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735] 0.89079 -0.49409 ADIQTER 0 0 0 0 0 0 0 9.04032 9.15853 11.0719 8.53613 0 10.1639 0 0 0 0 0 0 10.6546 0 10.486 0 0 0 0 0 P62304 RUXE_HUMAN Small nuclear ribonucleoprotein E (snRNP-E) (Sm protein E) (Sm-E) (SmE) SNRPE Homo sapiens (Human) "7-methylguanosine cap hypermethylation [GO:0036261]; mRNA splicing, via spliceosome [GO:0000398]; spliceosomal complex assembly [GO:0000245]; spliceosomal snRNP assembly [GO:0000387]; U2-type prespliceosome assembly [GO:1903241]" catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; methylosome [GO:0034709]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; precatalytic spliceosome [GO:0071011]; small nuclear ribonucleoprotein complex [GO:0030532]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697]; U1 snRNP [GO:0005685]; U12-type spliceosomal complex [GO:0005689]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4 snRNP [GO:0005687]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; U7 snRNP [GO:0005683] RNA binding [GO:0003723] 0.020316 1.5873 VMVQPINLIFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.82677 9.50557 9.59173 0 0 8.3052 8.96645 8.35403 9.05346 8.57596 9.507 9.04721 0 P62310 LSM3_HUMAN U6 snRNA-associated Sm-like protein LSm3 LSM3 MDS017 Homo sapiens (Human) "mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; P-body assembly [GO:0033962]" catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; Lsm1-7-Pat1 complex [GO:1990726]; Lsm2-8 complex [GO:0120115]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; precatalytic spliceosome [GO:0071011]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U6 snRNP [GO:0005688] RNA binding [GO:0003723]; U6 snRNA 3'-end binding [GO:0030629] 0.92774 -1.1975 IYVKMRNDR 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2481 0 0 0 0 0 0 0 0 0 0 0 0 0 P62316 SMD2_HUMAN Small nuclear ribonucleoprotein Sm D2 (Sm-D2) (snRNP core protein D2) SNRPD2 SNRPD1 Homo sapiens (Human) "7-methylguanosine cap hypermethylation [GO:0036261]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245]; spliceosomal snRNP assembly [GO:0000387]; U2-type prespliceosome assembly [GO:1903241]" catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; methylosome [GO:0034709]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; precatalytic spliceosome [GO:0071011]; small nuclear ribonucleoprotein complex [GO:0030532]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; U12-type spliceosomal complex [GO:0005689]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4 snRNP [GO:0005687]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682] RNA binding [GO:0003723] 0.88483 -0.33119 NNTQVLINCRNNKK 0 0 0 0 0 0 0 0 0 10.1919 10.0782 0 0 0 0 0 0 0 8.72298 0 8.78656 0 0 0 8.85577 0 0 P62318 SMD3_HUMAN Small nuclear ribonucleoprotein Sm D3 (Sm-D3) (snRNP core protein D3) SNRPD3 Homo sapiens (Human) "7-methylguanosine cap hypermethylation [GO:0036261]; mRNA splicing, via spliceosome [GO:0000398]; protein methylation [GO:0006479]; RNA splicing [GO:0008380]; spliceosomal snRNP assembly [GO:0000387]; U2-type prespliceosome assembly [GO:1903241]" catalytic step 2 spliceosome [GO:0071013]; commitment complex [GO:0000243]; cytosol [GO:0005829]; methylosome [GO:0034709]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; precatalytic spliceosome [GO:0071011]; small nuclear ribonucleoprotein complex [GO:0030532]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; spliceosomal tri-snRNP complex [GO:0097526]; telomerase holoenzyme complex [GO:0005697]; U1 snRNP [GO:0005685]; U12-type spliceosomal complex [GO:0005689]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4 snRNP [GO:0005687]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; U7 snRNP [GO:0005683] enzyme binding [GO:0019899]; histone pre-mRNA DCP binding [GO:0071208]; RNA binding [GO:0003723]; telomerase RNA binding [GO:0070034]; U7 snRNA binding [GO:0071209] 0 3.1951 FLILPDMLK 8.67172 8.50748 8.53185 0 0 0 9.31288 9.37528 9.16586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P62333 PRS10_HUMAN 26S proteasome regulatory subunit 10B (26S proteasome AAA-ATPase subunit RPT4) (Proteasome 26S subunit ATPase 6) (Proteasome subunit p42) PSMC6 SUG2 Homo sapiens (Human) positive regulation of inclusion body assembly [GO:0090261]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of RNA polymerase II transcription preinitiation complex assembly [GO:0045899]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; ubiquitin-dependent ERAD pathway [GO:0030433] "cytosol [GO:0005829]; cytosolic proteasome complex [GO:0031597]; extracellular exosome [GO:0070062]; inclusion body [GO:0016234]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome accessory complex [GO:0022624]; proteasome complex [GO:0000502]; proteasome regulatory particle, base subcomplex [GO:0008540]" ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; identical protein binding [GO:0042802]; proteasome-activating activity [GO:0036402]; protein-macromolecule adaptor activity [GO:0030674] 0.92178 -1.1229 IHIDLPNEQAR 0 0 0 0 0 0 0 0 0 0 0 9.02735 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P62424 RL7A_HUMAN Large ribosomal subunit protein eL8 (60S ribosomal protein L7a) (PLA-X polypeptide) (Surfeit locus protein 3) RPL7A SURF-3 SURF3 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; ribosome biogenesis [GO:0042254]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; polysomal ribosome [GO:0042788]; synapse [GO:0045202] cadherin binding [GO:0045296]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0 4.8186 AGVNTVTTLVENKK 0 8.94266 10.067 0 0 0 10.0699 10.4826 9.95337 0 9.73168 0 12.2278 0 11.0011 10.6143 11.4099 10.5659 10.0097 9.88847 10.989 0 0 0 11.3987 10.554 10.8462 P62491 RB11A_HUMAN Ras-related protein Rab-11A (Rab-11) (EC 3.6.5.2) (YL8) RAB11A RAB11 Homo sapiens (Human) "amyloid-beta clearance by transcytosis [GO:0150093]; astral microtubule organization [GO:0030953]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to organelle [GO:0072594]; establishment of vesicle localization [GO:0051650]; exocytosis [GO:0006887]; exosomal secretion [GO:1990182]; melanosome transport [GO:0032402]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; multivesicular body assembly [GO:0036258]; neuron projection development [GO:0031175]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; plasma membrane to endosome transport [GO:0048227]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; regulation of cytokinesis [GO:0032465]; regulation of multivesicular body size [GO:0010796]; regulation of vesicle-mediated transport [GO:0060627]; vesicle-mediated transport [GO:0016192]" centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; cleavage furrow [GO:0032154]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; multivesicular body [GO:0005771]; phagocytic vesicle [GO:0045335]; postsynaptic recycling endosome [GO:0098837]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; spindle pole [GO:0000922]; trans-Golgi network [GO:0005802]; transport vesicle [GO:0030133]; vesicle [GO:0031982] G protein activity [GO:0003925]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; microtubule binding [GO:0008017]; myosin V binding [GO:0031489]; syntaxin binding [GO:0019905] 0.89859 -0.57642 AQIWDTAGQER 0 0 0 0 0 0 0 0 9.91943 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P62495 ERF1_HUMAN Eukaryotic peptide chain release factor subunit 1 (Eukaryotic release factor 1) (eRF1) (Protein Cl1) (TB3-1) ETF1 ERF1 RF1 SUP45L1 Homo sapiens (Human) "cytoplasmic translational termination [GO:0002184]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; protein methylation [GO:0006479]; regulation of translational termination [GO:0006449]; translational termination [GO:0006415]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; translation release factor complex [GO:0018444] "aminoacyl-tRNA hydrolase activity [GO:0004045]; enzyme activator activity [GO:0008047]; nucleoside-triphosphatase regulator activity [GO:0060589]; ribosome binding [GO:0043022]; RNA binding [GO:0003723]; sequence-specific mRNA binding [GO:1990825]; translation release factor activity [GO:0003747]; translation release factor activity, codon specific [GO:0016149]; translation termination factor activity [GO:0008079]" 0.94078 -1.3116 FHTEALTALLSDDSK 9.65051 0 0 0 0 0 0 0 10.1973 0 0 0 0 0 0 0 0 0 0 0 10.6395 0 0 0 0 0 0 P62701 RS4X_HUMAN "Small ribosomal subunit protein eS4, X isoform (40S ribosomal protein S4) (SCR10) (Single copy abundant mRNA protein)" RPS4X CCG2 RPS4 SCAR Homo sapiens (Human) cytoplasmic translation [GO:0002181]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of translation [GO:0045727]; ribosomal small subunit biogenesis [GO:0042274]; translation [GO:0006412] cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; polysome [GO:0005844]; ribonucleoprotein complex [GO:1990904]; ribosome [GO:0005840]; small ribosomal subunit [GO:0015935]; small-subunit processome [GO:0032040]; synapse [GO:0045202] RNA binding [GO:0003723]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735] 0.034934 1.5081 IGVITNR 0 0 0 0 0 0 9.16754 9.30172 9.44909 0 9.8805 8.71469 0 9.56908 9.48309 0 9.72342 9.13509 0 0 0 0 9.21327 8.83048 0 10.3233 11.5362 P62714 PP2AB_HUMAN Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PP2A-beta) (EC 3.1.3.16) PPP2CB Homo sapiens (Human) apoptotic mitochondrial changes [GO:0008637]; mitotic cell cycle [GO:0000278]; negative regulation of gene expression [GO:0010629]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein dephosphorylation [GO:0006470]; response to antibiotic [GO:0046677]; response to endoplasmic reticulum stress [GO:0034976]; response to hydrogen peroxide [GO:0042542]; response to lead ion [GO:0010288] "chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; nucleus [GO:0005634]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]" metal ion binding [GO:0046872]; myosin phosphatase activity [GO:0017018]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]; transmembrane transporter binding [GO:0044325] 0.96408 -2.2739 DDKAFTKELDQWVEQLNECK 0 12.1993 0 0 0 0 0 0 0 11.703 0 0 0 0 0 0 10.4044 0 0 9.38089 0 0 0 0 0 0 0 P62753 RS6_HUMAN Small ribosomal subunit protein eS6 (40S ribosomal protein S6) (Phosphoprotein NP33) RPS6 OK/SW-cl.2 Homo sapiens (Human) activation-induced cell death of T cells [GO:0006924]; cytoplasmic translation [GO:0002181]; erythrocyte development [GO:0048821]; G1/S transition of mitotic cell cycle [GO:0000082]; gastrulation [GO:0007369]; glucose homeostasis [GO:0042593]; mammalian oogenesis stage [GO:0022605]; negative regulation of apoptotic process [GO:0043066]; placenta development [GO:0001890]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364]; T cell differentiation in thymus [GO:0033077]; T cell proliferation involved in immune response [GO:0002309]; TOR signaling [GO:0031929]; translation [GO:0006412] cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; polysome [GO:0005844]; ribonucleoprotein complex [GO:1990904]; small ribosomal subunit [GO:0015935]; small-subunit processome [GO:0032040] protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.0080429 2.0744 DIPGLTDTTVPR 8.91558 8.95286 8.80371 0 0 0 9.8201 9.78252 9.60958 0 0 0 0 0 0 0 0 0 10.0503 0 0 8.95733 0 0 11.4536 11.2527 11.3628 P62760 VISL1_HUMAN Visinin-like protein 1 (VILIP) (VLP-1) (Hippocalcin-like protein 3) (HLP3) VSNL1 VISL1 Homo sapiens (Human) negative regulation of insulin secretion [GO:0046676]; positive regulation of exocytosis [GO:0045921]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774] cytosol [GO:0005829]; membrane [GO:0016020] calcium ion binding [GO:0005509] 0.36679 0.73824 LAPEVMEDLVK 0 0 10.8845 0 0 0 10.2439 10.2204 0 0 10.8553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P62805 H4_HUMAN Histone H4 H4C1 H4/A H4FA HIST1H4A; H4C2 H4/I H4FI HIST1H4B; H4C3 H4/G H4FG HIST1H4C; H4C4 H4/B H4FB HIST1H4D; H4C5 H4/J H4FJ HIST1H4E; H4C6 H4/C H4FC HIST1H4F; H4C8 H4/H H4FH HIST1H4H; H4C9 H4/M H4FM HIST1H4I; H4C11 H4/E H4FE HIST1H4J; H4C12 H4/D H4FD HIST1H4K; H4C13 H4/K H4FK HIST1H4L; H4C14 H4/N H4F2 H4FN HIST2H4 HIST2H4A; H4C15 H4/O H4FO HIST2H4B; H4C16 H4-16 HIST4H4 Homo sapiens (Human) negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein localization to CENP-A containing chromatin [GO:0061644]; telomere organization [GO:0032200] "CENP-A containing nucleosome [GO:0043505]; chromosome, telomeric region [GO:0000781]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]" DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; structural constituent of chromatin [GO:0030527] 0 11.769 DAVTYTEHAK 10.9083 10.6217 11.2707 0 0 0 10.9374 9.76404 10.9639 12.4666 12.8923 11.4655 10.0643 0 0 10.1378 0 11.0768 11.3495 10.9607 10.5209 11.4202 0 10.6411 0 0 0 P62820 RAB1A_HUMAN Ras-related protein Rab-1A (EC 3.6.5.2) (YPT1-related protein) RAB1A RAB1 Homo sapiens (Human) autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; cell migration [GO:0016477]; COPII-coated vesicle cargo loading [GO:0090110]; defense response to bacterium [GO:0042742]; endocytosis [GO:0006897]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; growth hormone secretion [GO:0030252]; intracellular protein transport [GO:0006886]; melanosome transport [GO:0032402]; positive regulation of glycoprotein metabolic process [GO:1903020]; positive regulation of interleukin-8 production [GO:0032757]; substrate adhesion-dependent cell spreading [GO:0034446]; vesicle transport along microtubule [GO:0047496]; vesicle-mediated transport [GO:0016192]; virion assembly [GO:0019068] cytosol [GO:0005829]; early endosome [GO:0005769]; endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; melanosome [GO:0042470]; transport vesicle membrane [GO:0030658] cadherin binding [GO:0045296]; G protein activity [GO:0003925]; GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0 3.5504 EFADSLGIPFLETSAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.94268 8.39695 9.27377 10.1504 10.6651 P62826 RAN_HUMAN GTP-binding nuclear protein Ran (EC 3.6.5.-) (Androgen receptor-associated protein 24) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein) RAN ARA24 OK/SW-cl.81 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell division [GO:0051301]; cellular response to mineralocorticoid stimulus [GO:0071389]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; hippocampus development [GO:0021766]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; ribosomal subunit export from nucleus [GO:0000054]; snRNA import into nucleus [GO:0061015]; spermatid development [GO:0007286]; viral process [GO:0016032] centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; male germ cell nucleus [GO:0001673]; manchette [GO:0002177]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; sperm flagellum [GO:0036126] cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; dynein intermediate chain binding [GO:0045505]; G protein activity [GO:0003925]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; importin-alpha family protein binding [GO:0061676]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723] 0 22.337 AAQGEPQVQFK 11.4788 10.1297 10.2096 0 0 0 12.0546 11.2363 12.119 11.0957 11.0645 10.9804 8.55884 0 0 0 10.7759 10.5385 9.66646 11.5858 10.4342 8.54009 0 0 10.9984 11.2731 11.1004 P62847 RS24_HUMAN Small ribosomal subunit protein eS24 (40S ribosomal protein S24) RPS24 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; erythrocyte homeostasis [GO:0034101]; ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; endoplasmic reticulum [GO:0005783]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; small ribosomal subunit [GO:0015935]; small-subunit processome [GO:0032040] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; translation initiation factor binding [GO:0031369] 0.13509 1.0531 EKLAKMYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.62344 0 0 0 9.25934 9.23683 9.70316 0 10.1416 10.5215 0 0 0 P62851 RS25_HUMAN Small ribosomal subunit protein eS25 (40S ribosomal protein S25) RPS25 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; extracellular exosome [GO:0070062]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; ribosome [GO:0005840]; small ribosomal subunit [GO:0015935] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0 4.7412 AALQELLSK 8.47492 8.79383 9.18842 0 0 0 0 9.51215 9.55444 0 11.3847 9.13627 0 0 0 0 0 9.98968 9.32346 9.32339 9.58986 9.42738 0 8.48273 0 0 11.2198 P62854 RS26_HUMAN Small ribosomal subunit protein eS26 (40S ribosomal protein S26) RPS26 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; negative regulation of RNA splicing [GO:0033119]; translation [GO:0006412] cytoplasm [GO:0005737]; cytoplasmic side of rough endoplasmic reticulum membrane [GO:0098556]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; polysomal ribosome [GO:0042788]; small ribosomal subunit [GO:0015935]; synapse [GO:0045202] cadherin binding [GO:0045296]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0 16.1 DISEASVFDAYVLPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.37471 9.0471 0 0 0 0 0 0 0 9.94268 10.926 11.314 P62857 RS28_HUMAN Small ribosomal subunit protein eS28 (40S ribosomal protein S28) RPS28 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; maturation of SSU-rRNA [GO:0030490]; ribosomal small subunit assembly [GO:0000028]; ribosomal small subunit biogenesis [GO:0042274]; ribosome biogenesis [GO:0042254]; rRNA processing [GO:0006364]; translation [GO:0006412] cytoplasm [GO:0005737]; cytoplasmic side of rough endoplasmic reticulum membrane [GO:0098556]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; extracellular exosome [GO:0070062]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; polysomal ribosome [GO:0042788]; small ribosomal subunit [GO:0015935]; small-subunit processome [GO:0032040]; synapse [GO:0045202] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0 6.1487 EGDVLTLLESER 0 0 0 0 0 0 8.80378 8.74261 8.60363 0 0 0 0 9.27622 9.3901 9.82863 9.97255 9.22113 0 0 0 0 0 0 0 10.0779 9.88231 P62873 GBB1_HUMAN Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1) GNB1 Homo sapiens (Human) adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cell population proliferation [GO:0008283]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor signaling pathway [GO:0007186]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; Ras protein signal transduction [GO:0007265]; retina development in camera-type eye [GO:0060041]; sensory perception of taste [GO:0050909]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular vesicle [GO:1903561]; heterotrimeric G-protein complex [GO:0005834]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; photoreceptor disc membrane [GO:0097381]; plasma membrane [GO:0005886]; synapse [GO:0045202] GTPase activity [GO:0003924]; GTPase binding [GO:0051020]; protein-containing complex binding [GO:0044877]; signaling receptor complex adaptor activity [GO:0030159] 0.60522 0.43649 ACADATLSQITNNIDPVGR 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0603 0 0 0 0 0 0 0 0 0 0 0 0 0 P62906 RL10A_HUMAN Large ribosomal subunit protein uL1 (60S ribosomal protein L10a) (CSA-19) (Neural precursor cell expressed developmentally down-regulated protein 6) (NEDD-6) RPL10A NEDD6 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; polysomal ribosome [GO:0042788] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.0084746 2.2509 DTLYEAVR 0 12.0607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.89203 0 0 0 0 0 0 0 0 0 P62910 RL32_HUMAN Large ribosomal subunit protein eL32 (60S ribosomal protein L32) RPL32 PP9932 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; membrane [GO:0016020]; polysomal ribosome [GO:0042788]; synapse [GO:0045202] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.95436 -1.5237 TKHMLPSGFR 0 0 0 0 0 0 0 0 0 0 8.28993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P62913 RL11_HUMAN Large ribosomal subunit protein uL5 (60S ribosomal protein L11) (CLL-associated antigen KW-12) RPL11 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein neddylation [GO:2000435]; negative regulation of ubiquitin protein ligase activity [GO:1904667]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; positive regulation of gene expression [GO:0010628]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of protein binding [GO:0032092]; protein localization to nucleus [GO:0034504]; protein stabilization [GO:0050821]; protein targeting [GO:0006605]; regulation of signal transduction by p53 class mediator [GO:1901796]; ribosomal large subunit assembly [GO:0000027]; ribosomal large subunit biogenesis [GO:0042273]; rRNA processing [GO:0006364]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; polysomal ribosome [GO:0042788]; protein-containing complex [GO:0032991] 5S rRNA binding [GO:0008097]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin ligase inhibitor activity [GO:1990948]; ubiquitin protein ligase binding [GO:0031625] 0 3.6842 AEEILEK 0 0 0 0 0 0 0 8.84511 0 0 0 9.09901 0 11.9786 0 0 12.4584 12.2857 0 0 0 0 0 0 12.7825 12.8864 12.7096 P62917 RL8_HUMAN Large ribosomal subunit protein uL2 (60S ribosomal protein L8) RPL8 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; focal adhesion [GO:0005925]; membrane [GO:0016020]; polysomal ribosome [GO:0042788]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069] RNA binding [GO:0003723]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735] 0 5.537 ASGNYATVISHNPETK 0 0 0 0 0 0 9.7233 9.89078 9.64758 9.48591 9.54261 9.44168 8.81375 8.59238 8.8213 0 0 10.242 0 0 0 9.38642 8.64591 0 9.93575 10.7882 10.9311 P62937 PPIA_HUMAN "Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin A) (Cyclosporin A-binding protein) (Rotamase A) [Cleaved into: Peptidyl-prolyl cis-trans isomerase A, N-terminally processed]" PPIA CYPA Homo sapiens (Human) activation of protein kinase B activity [GO:0032148]; apoptotic process [GO:0006915]; cell adhesion molecule production [GO:0060352]; cellular response to oxidative stress [GO:0034599]; endothelial cell activation [GO:0042118]; leukocyte chemotaxis [GO:0030595]; lipid droplet organization [GO:0034389]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein K48-linked ubiquitination [GO:0061944]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of viral life cycle [GO:1903901]; neutrophil chemotaxis [GO:0030593]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; regulation of apoptotic signaling pathway [GO:2001233]; regulation of viral genome replication [GO:0045069]; viral release from host cell [GO:0019076] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982] cyclosporin A binding [GO:0016018]; heparan sulfate binding [GO:1904399]; integrin binding [GO:0005178]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790] 0 108.7 EGMNIVEAMER 10.8001 11.3799 10.5972 10.4057 11.2011 10.6768 11.921 11.3607 12.0142 11.1634 0 8.94983 11.7919 12.4507 11.9736 12.6703 12.7344 11.7177 10.9465 9.98513 10.9753 10.6527 10.3277 10.9275 12.7349 12.2117 10.5094 P62942 FKB1A_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP1A (PPIase FKBP1A) (EC 5.2.1.8) (12 kDa FK506-binding protein) (12 kDa FKBP) (FKBP-12) (Calstabin-1) (FK506-binding protein 1A) (FKBP-1A) (Immunophilin FKBP12) (Rotamase) FKBP1A FKBP1 FKBP12 Homo sapiens (Human) 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010] cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018] activin binding [GO:0048185]; FK506 binding [GO:0005528]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; transmembrane transporter binding [GO:0044325]; type I transforming growth factor beta receptor binding [GO:0034713] 0.9501 -1.3813 GVQVETISPGDGRTFPKR 0 0 0 0 0 0 0 0 0 0 0 0 10.6474 0 0 0 0 11.7578 0 0 0 0 0 0 0 0 0 P62955 CCG7_HUMAN Voltage-dependent calcium channel gamma-7 subunit (Neuronal voltage-gated calcium channel gamma-7 subunit) (Transmembrane AMPAR regulatory protein gamma-7) (TARP gamma-7) CACNG7 Homo sapiens (Human) "calcium ion transport [GO:0006816]; neurotransmitter receptor internalization [GO:0099590]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; neurotransmitter receptor transport, postsynaptic endosome to lysosome [GO:0098943]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; regulation of AMPA receptor activity [GO:2000311]; regulation of monoatomic ion transmembrane transport [GO:0034765]; regulation of mRNA stability [GO:0043488]; transmission of nerve impulse [GO:0019226]" AMPA glutamate receptor complex [GO:0032281]; cerebellar mossy fiber [GO:0044300]; early endosome [GO:0005769]; glutamatergic synapse [GO:0098978]; L-type voltage-gated calcium channel complex [GO:1990454]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; voltage-gated calcium channel complex [GO:0005891] calcium channel regulator activity [GO:0005246]; channel regulator activity [GO:0016247]; voltage-gated calcium channel activity [GO:0005245] 0.95272 -1.4642 LSDCSDYSGQFLQPEAWRRGR 0 0 0 0 0 0 9.25913 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P62979 RS27A_HUMAN Ubiquitin-ribosomal protein eS31 fusion protein (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31 (40S ribosomal protein S27a)] RPS27A UBA80 UBCEP1 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]; ribosomal small subunit biogenesis [GO:0042274]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; small ribosomal subunit [GO:0015935]; small-subunit processome [GO:0032040]; vesicle [GO:0031982] metal ion binding [GO:0046872]; protein tag [GO:0031386]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625] 0 220.04 EGIPPDQQR 13.6518 14.5579 14.4743 8.61578 8.95492 8.70712 12.9357 13.1621 12.9946 13.8105 14.3881 14.3896 11.8605 12.4319 11.9476 13.0573 13.2946 12.3898 13.1123 13.3588 13.6289 10.7926 11.9737 11.5804 12.9359 13.6454 13.0835 P62995 TRA2B_HUMAN "Transformer-2 protein homolog beta (TRA-2 beta) (TRA2-beta) (hTRA2-beta) (Splicing factor, arginine/serine-rich 10) (Transformer-2 protein homolog B)" TRA2B SFRS10 Homo sapiens (Human) "cellular response to glucose stimulus [GO:0071333]; cerebral cortex regionalization [GO:0021796]; embryonic brain development [GO:1990403]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of RNA splicing [GO:0043484]; RNA splicing, via transesterification reactions [GO:0000375]" nuclear inner membrane [GO:0005637]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spliceosomal complex [GO:0005681] identical protein binding [GO:0042802]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723] 0.97016 -5.1984 DLREVFSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.76421 0 0 0 9.50944 0 0 0 0 0 0 0 0 P63000 RAC1_HUMAN Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1) RAC1 TC25 MIG5 Homo sapiens (Human) "actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell motility [GO:0048870]; cell-matrix adhesion [GO:0007160]; cortical cytoskeleton organization [GO:0030865]; engulfment of apoptotic cell [GO:0043652]; establishment or maintenance of cell polarity [GO:0007163]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; localization [GO:0051179]; localization within membrane [GO:0051668]; motor neuron axon guidance [GO:0008045]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of interleukin-23 production [GO:0032707]; negative regulation of receptor-mediated endocytosis [GO:0048261]; neuron migration [GO:0001764]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; Rac protein signal transduction [GO:0016601]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of lamellipodium assembly [GO:0010591]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of respiratory burst [GO:0060263]; regulation of stress fiber assembly [GO:0051492]; respiratory burst [GO:0045730]; response to wounding [GO:0009611]; ruffle assembly [GO:0097178]; ruffle organization [GO:0031529]; semaphorin-plexin signaling pathway [GO:0071526]; small GTPase mediated signal transduction [GO:0007264]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; substrate adhesion-dependent cell spreading [GO:0034446]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic vesicle [GO:0031410]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; membrane [GO:0016020]; NADPH oxidase complex [GO:0043020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; recycling endosome membrane [GO:0055038]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802] enzyme binding [GO:0019899]; G protein activity [GO:0003925]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; molecular adaptor activity [GO:0060090]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; Rho GDP-dissociation inhibitor binding [GO:0051022]; thioesterase binding [GO:0031996] 0.6058 0.43625 TVFDEAIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0773 9.71516 8.95542 0 0 0 0 0 10.468 P63010 AP2B1_HUMAN AP-2 complex subunit beta (AP105B) (Adaptor protein complex AP-2 subunit beta) (Adaptor-related protein complex 2 subunit beta) (Beta-2-adaptin) (Beta-adaptin) (Clathrin assembly protein complex 2 beta large chain) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit) AP2B1 ADTB2 CLAPB1 Homo sapiens (Human) aorta development [GO:0035904]; clathrin-dependent endocytosis [GO:0072583]; coronary vasculature development [GO:0060976]; intracellular protein transport [GO:0006886]; kidney development [GO:0001822]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; synaptic vesicle endocytosis [GO:0048488]; ventricular septum development [GO:0003281]; vesicle-mediated transport [GO:0016192] AP-2 adaptor complex [GO:0030122]; clathrin adaptor complex [GO:0030131]; clathrin-coated endocytic vesicle [GO:0045334]; clathrin-coated endocytic vesicle membrane [GO:0030669]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endolysosome membrane [GO:0036020]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; presynapse [GO:0098793] clathrin binding [GO:0030276]; signal sequence binding [GO:0005048] 0.7987 0.2397 ALAVRTMGCIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2692 0 0 0 0 0 0 0 0 0 0 P63104 1433Z_HUMAN 14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1) YWHAZ Homo sapiens (Human) angiogenesis [GO:0001525]; ERK1 and ERK2 cascade [GO:0070371]; establishment of Golgi localization [GO:0051683]; Golgi reassembly [GO:0090168]; lung development [GO:0030324]; negative regulation of apoptotic process [GO:0043066]; negative regulation of innate immune response [GO:0045824]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein phosphorylation [GO:0006468]; protein targeting [GO:0006605]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of synapse maturation [GO:0090128]; respiratory system process [GO:0003016]; signal transduction [GO:0007165]; synaptic target recognition [GO:0008039]; tube formation [GO:0035148] blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; melanosome [GO:0042470]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; vesicle [GO:0031982] cadherin binding [GO:0045296]; DNA-binding transcription factor binding [GO:0140297]; identical protein binding [GO:0042802]; phosphoserine residue binding [GO:0050815]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein sequestering activity [GO:0140311]; RNA binding [GO:0003723]; transmembrane transporter binding [GO:0044325]; ubiquitin protein ligase binding [GO:0031625] 0 45.652 DNLTLWTSDTQGDEAEAGEGGEN 11.9151 10.5715 11.2398 0 9.36717 9.90929 12.2676 12.4242 12.6479 13.3083 12.7191 12.6913 11.2807 11.787 12.3944 12.466 11.2859 11.3457 11.9035 11.6808 11.1255 11.3117 12.245 12.6778 13.6201 13.193 13.3465 P63128 POK9_HUMAN Endogenous retrovirus group K member 9 Pol protein (HERV-K(C6) Gag-Pol protein) (HERV-K109 Gag-Pol protein) (HERV-K_6q14.1 provirus ancestral Gag-Pol polyprotein) [Includes: Protease (EC 3.4.23.50) (PR) (Retropepsin); Reverse transcriptase/ribonuclease H (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p66 RT)] ERVK-9 Homo sapiens (Human) proteolysis [GO:0006508]; viral process [GO:0016032] plasma membrane [GO:0005886] aspartic-type endopeptidase activity [GO:0004190]; DNA-directed DNA polymerase activity [GO:0003887]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270] 0.96199 -2.5557 AICLRAWEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.37482 0 0 0 0 0 P63135 POK7_HUMAN Endogenous retrovirus group K member 7 Pol protein (HERV-K(III) Pol protein) (HERV-K102 Pol protein) (HERV-K_1q22 provirus ancestral Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (RNase H) (EC 3.1.26.4); Integrase (IN)] ERVK-7 Homo sapiens (Human) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; DNA repair [GO:0006281] DNA binding [GO:0003677]; RNA stem-loop binding [GO:0035613]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270] 0.96935 -3.4039 DSDHRER 0 0 0 0 0 0 0 8.26416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P63145 GAK24_HUMAN Endogenous retrovirus group K member 24 Gag polyprotein (HERV-K101 Gag protein) (HERV-K_22q11.21 provirus ancestral Gag polyprotein) (Gag polyprotein) ERVK-24 Homo sapiens (Human) viral process [GO:0016032] plasma membrane [GO:0005886] nucleic acid binding [GO:0003676]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270] 0.9608 -2.0057 AICLRAWEK 8.87879 0 0 0 0 0 0 0 0 0 0 0 9.90421 0 9.46115 0 0 0 10.2016 0 0 0 0 0 0 9.69573 0 P63151 2ABA_HUMAN Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PP2A subunit B isoform B55-alpha) (PP2A subunit B isoform PR55-alpha) (PP2A subunit B isoform R2-alpha) (PP2A subunit B isoform alpha) PPP2R2A Homo sapiens (Human) protein dephosphorylation [GO:0006470]; response to morphine [GO:0043278] cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; nucleoplasm [GO:0005654]; protein phosphatase type 2A complex [GO:0000159] protein phosphatase regulator activity [GO:0019888] 0.96933 -4.1179 INKIRWLPQK 0 0 0 0 0 0 0 0 0 0 0 8.74873 0 0 0 0 0 0 0 0 0 0 0 0 8.5775 0 0 P63173 RL38_HUMAN Large ribosomal subunit protein eL38 (60S ribosomal protein L38) RPL38 Homo sapiens (Human) 90S preribosome assembly [GO:0034463]; axial mesoderm development [GO:0048318]; cytoplasmic translation [GO:0002181]; middle ear morphogenesis [GO:0042474]; ossification [GO:0001503]; regulation of translation [GO:0006417]; ribonucleoprotein complex assembly [GO:0022618]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; eukaryotic 80S initiation complex [GO:0033291]; focal adhesion [GO:0005925]; polysomal ribosome [GO:0042788]; postsynaptic density [GO:0014069] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.92425 -1.0144 IEEIKDFLLTAR 12.7737 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P63208 SKP1_HUMAN S-phase kinase-associated protein 1 (Cyclin-A/CDK2-associated protein p19) (p19A) (Organ of Corti protein 2) (OCP-2) (Organ of Corti protein II) (OCP-II) (RNA polymerase II elongation factor-like protein) (SIII) (Transcription elongation factor B polypeptide 1-like) (p19skp1) SKP1 EMC19 OCP2 SKP1A TCEB1L Homo sapiens (Human) chromatin remodeling [GO:0006338]; maintenance of protein location in nucleus [GO:0051457]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PcG protein complex [GO:0031519]; SCF ubiquitin ligase complex [GO:0019005] beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; F-box domain binding [GO:1990444]; molecular function activator activity [GO:0140677]; protein domain specific binding [GO:0019904]; ubiquitin ligase complex scaffold activity [GO:0160072]; ubiquitin ligase-substrate adaptor activity [GO:1990756] 0.80298 0.24034 GLLDVTCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3075 9.48583 P63220 RS21_HUMAN Small ribosomal subunit protein eS21 (40S ribosomal protein S21) RPS21 Homo sapiens (Human) "cytoplasmic translation [GO:0002181]; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000461]; translation [GO:0006412]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; nucleoplasm [GO:0005654]; polysomal ribosome [GO:0042788]; rough endoplasmic reticulum [GO:0005791]; small ribosomal subunit [GO:0015935]; synapse [GO:0045202] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.88292 -0.11136 LAKADGIVSK 0 0 0 0 0 0 0 0 10.3203 10.8739 11.3785 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P63244 RACK1_HUMAN "Small ribosomal subunit protein RACK1 (Cell proliferation-inducing gene 21 protein) (Guanine nucleotide-binding protein subunit beta-2-like 1) (Guanine nucleotide-binding protein subunit beta-like protein 12.3) (Human lung cancer oncogene 7 protein) (HLC-7) (Receptor for activated C kinase) (Receptor of activated protein C kinase 1) [Cleaved into: Small ribosomal subunit protein RACK1, N-terminally processed (Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed) (Receptor of activated protein C kinase 1, N-terminally processed)]" RACK1 GNB2L1 HLC7 PIG21 Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cell cycle [GO:0007049]; cellular response to glucose stimulus [GO:0071333]; cellular response to growth factor stimulus [GO:0071363]; cytoplasmic translation [GO:0002181]; gastrulation [GO:0007369]; negative regulation of cell growth [GO:0030308]; negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein binding [GO:0032091]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of translation [GO:0017148]; negative regulation of Wnt signaling pathway [GO:0030178]; pigmentation [GO:0043473]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of gastrulation [GO:2000543]; positive regulation of Golgi to plasma membrane protein transport [GO:0042998]; positive regulation of GTPase activity [GO:0043547]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein-containing complex assembly [GO:0031334]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of establishment of cell polarity [GO:2000114]; regulation of protein localization [GO:0032880]; rescue of stalled ribosome [GO:0072344]; rhythmic process [GO:0048511] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; IRE1-RACK1-PP2A complex [GO:1990630]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; phagocytic cup [GO:0001891]; small ribosomal subunit [GO:0015935] BH3 domain binding [GO:0051434]; cadherin binding [GO:0045296]; cyclin binding [GO:0030332]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; enzyme binding [GO:0019899]; ion channel inhibitor activity [GO:0008200]; molecular adaptor activity [GO:0060090]; protein homodimerization activity [GO:0042803]; protein kinase C binding [GO:0005080]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase inhibitor activity [GO:0030292]; receptor tyrosine kinase binding [GO:0030971]; ribosome binding [GO:0043022]; RNA binding [GO:0003723]; SH2 domain binding [GO:0042169]; signaling adaptor activity [GO:0035591]; signaling receptor binding [GO:0005102]; translation regulator activity [GO:0045182] 0 6.4419 DETNYGIPQR 0 0 0 0 0 0 8.81836 8.51029 0 0 0 9.03172 0 9.35235 10.7634 0 0 10.0661 9.63483 0 0 9.53171 0 0 10.4713 0 0 P63261 ACTG_HUMAN "Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]" ACTG1 ACTG Homo sapiens (Human) angiogenesis [GO:0001525]; cellular response to type II interferon [GO:0071346]; maintenance of blood-brain barrier [GO:0035633]; morphogenesis of a polarized epithelium [GO:0001738]; platelet aggregation [GO:0070527]; positive regulation of cell migration [GO:0030335]; positive regulation of gene expression [GO:0010628]; positive regulation of wound healing [GO:0090303]; protein localization to bicellular tight junction [GO:1902396]; regulation of focal adhesion assembly [GO:0051893]; regulation of stress fiber assembly [GO:0051492]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of transepithelial transport [GO:0150111]; response to calcium ion [GO:0051592]; response to mechanical stimulus [GO:0009612]; retina homeostasis [GO:0001895]; sarcomere organization [GO:0045214]; tight junction assembly [GO:0120192] actin filament [GO:0005884]; apical junction complex [GO:0043296]; basal body patch [GO:0120220]; blood microparticle [GO:0072562]; calyx of Held [GO:0044305]; cell-cell junction [GO:0005911]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dense body [GO:0097433]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filamentous actin [GO:0031941]; focal adhesion [GO:0005925]; membrane [GO:0016020]; myofibril [GO:0030016]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; postsynaptic actin cytoskeleton [GO:0098871]; presynaptic actin cytoskeleton [GO:0099143]; Schaffer collateral - CA1 synapse [GO:0098685] ATP binding [GO:0005524]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; profilin binding [GO:0005522]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of postsynaptic actin cytoskeleton [GO:0098973]; ubiquitin protein ligase binding [GO:0031625] 0 323.31 AGFAGDDAPR 15.1152 14.9456 14.9132 12.8604 12.8537 13.1266 16.0022 16.0697 16.0287 16.095 15.7792 16.0159 15.2409 15.2568 15.3566 16.0615 16.1112 15.8836 16.0479 15.7551 15.6802 15.5747 15.7799 15.6794 17.2335 17.1194 17.0585 P63267 ACTH_HUMAN "Actin, gamma-enteric smooth muscle (EC 3.6.4.-) (Alpha-actin-3) (Gamma-2-actin) (Smooth muscle gamma-actin) [Cleaved into: Actin, gamma-enteric smooth muscle, intermediate form]" ACTG2 ACTA3 ACTL3 ACTSG Homo sapiens (Human) mesenchyme migration [GO:0090131]; positive regulation of gene expression [GO:0010628] blood microparticle [GO:0072562]; cell body [GO:0044297]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; myosin filament [GO:0032982] ATP binding [GO:0005524]; hydrolase activity [GO:0016787] 0.88609 -0.33875 AGFAGDDAPR 0 0 0 0 0 0 8.82461 0 0 9.38614 0 0 0 0 0 0 0 0 0 9.45195 0 0 0 0 0 0 0 P67870 CSK2B_HUMAN Casein kinase II subunit beta (CK II beta) (Phosvitin) (Protein G5a) CSNK2B CK2N G5A Homo sapiens (Human) adiponectin-activated signaling pathway [GO:0033211]; endothelial tube morphogenesis [GO:0061154]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell population proliferation [GO:0008285]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of activin receptor signaling pathway [GO:0032927]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; protein phosphorylation [GO:0006468]; protein-containing complex assembly [GO:0065003]; regulation of DNA binding [GO:0051101]; regulation of protein serine/threonine phosphatase activity [GO:0080163]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein kinase CK2 complex [GO:0005956]; secretory granule lumen [GO:0034774] chromatin binding [GO:0003682]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein kinase regulator activity [GO:0019887]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; signaling receptor binding [GO:0005102] 0.8408 0.1804 CMDVYTPK 0 0 0 0 0 0 0 0 0 0 10.5326 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P67936 TPM4_HUMAN Tropomyosin alpha-4 chain (TM30p1) (Tropomyosin-4) TPM4 Homo sapiens (Human) actin filament organization [GO:0007015]; muscle contraction [GO:0006936]; osteoblast differentiation [GO:0001649] actin filament [GO:0005884]; cortical cytoskeleton [GO:0030863]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; muscle thin filament tropomyosin [GO:0005862]; podosome [GO:0002102]; stress fiber [GO:0001725] actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307] 0 17.126 AGLNSLEAVK 10.6985 0 10.3955 0 0 0 10.293 10.5568 10.541 11.8232 9.43077 11.2878 10.313 10.4262 10.44 11.8598 12.4898 10.9195 9.96185 10.2432 10.3906 10.9987 11.1525 10.0084 11.5738 11.4298 11.4992 P68104 EF1A1_HUMAN Elongation factor 1-alpha 1 (EF-1-alpha-1) (EC 3.6.5.-) (Elongation factor Tu) (EF-Tu) (Eukaryotic elongation factor 1 A-1) (eEF1A-1) (Leukocyte receptor cluster member 7) EEF1A1 EEF1A EF1A LENG7 Homo sapiens (Human) cellular response to epidermal growth factor stimulus [GO:0071364]; positive regulation by host of viral genome replication [GO:0044829]; regulation of chaperone-mediated autophagy [GO:1904714]; regulation of D-erythro-sphingosine kinase activity [GO:1900022]; translation [GO:0006412]; translational elongation [GO:0006414] cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoplasmic side of lysosomal membrane [GO:0098574]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; eukaryotic translation elongation factor 1 complex [GO:0005853]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; secretory granule lumen [GO:0034774] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; kinase binding [GO:0019900]; molecular adaptor activity [GO:0060090]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; translation elongation factor activity [GO:0003746]; tRNA binding [GO:0000049] 0 57.274 DMRQTVAVGVIK 14.1561 14.2305 14.1605 12.9763 13.5727 13.6062 15.2919 15.0336 15.3664 14.0714 14.6519 14.7465 15.2787 15.5666 15.6131 16.0889 16.1511 15.8274 14.2597 13.2973 14.3041 13.9588 14.1113 13.8581 16.0484 16.0556 15.9083 P68371 TBB4B_HUMAN Tubulin beta-4B chain (Tubulin beta-2 chain) (Tubulin beta-2C chain) TUBB4B TUBB2C Homo sapiens (Human) microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; natural killer cell mediated cytotoxicity [GO:0042267] azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular vesicle [GO:1903561]; intercellular bridge [GO:0045171]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; mitotic spindle [GO:0072686]; nucleus [GO:0005634] double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; MHC class I protein binding [GO:0042288]; structural constituent of cytoskeleton [GO:0005200]; unfolded protein binding [GO:0051082] 0 35.571 ALTVPELTQQMFDAK 11.5809 11.0501 11.022 0 0 0 11.4728 11.5308 11.9154 11.7014 0 9.71282 10.6627 0 10.1492 11.4606 11.3352 10.233 11.6928 12.1698 12.3768 11.0807 11.136 12.1358 13.3239 12.8305 12.9953 P68871 HBB_HUMAN Hemoglobin subunit beta (Beta-globin) (Hemoglobin beta chain) [Cleaved into: LVV-hemorphin-7; Spinorphin] HBB Homo sapiens (Human) blood vessel diameter maintenance [GO:0097746]; carbon dioxide transport [GO:0015670]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; nitric oxide transport [GO:0030185]; oxygen transport [GO:0015671]; platelet aggregation [GO:0070527]; positive regulation of cell death [GO:0010942]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; regulation of blood pressure [GO:0008217]; renal absorption [GO:0070293]; response to hydrogen peroxide [GO:0042542] blood microparticle [GO:0072562]; cytosol [GO:0005829]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; tertiary granule lumen [GO:1904724] heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344] 0.81815 0.21861 VVAGVANALAHK 0 0 10.3912 0 0 0 0 12.1548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P69905 HBA_HUMAN Hemoglobin subunit alpha (Alpha-globin) (Hemoglobin alpha chain) [Cleaved into: Hemopressin] HBA1; HBA2 Homo sapiens (Human) carbon dioxide transport [GO:0015670]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; nitric oxide transport [GO:0030185]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; response to hydrogen peroxide [GO:0042542] blood microparticle [GO:0072562]; cytosol [GO:0005829]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020] G protein-coupled receptor binding [GO:0001664]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344] 0.96904 -3.8955 VLSPADK 0 0 0 0 0 0 0 0 9.33693 0 0 12.1339 10.0283 9.92102 0 0 0 0 0 0 0 0 0 0 0 0 0 P78312 F193A_HUMAN Protein FAM193A (Protein IT14) FAM193A C4orf8 RES4-22 Homo sapiens (Human) 0.95998 -1.9805 EHLHLQEEQRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.492 0 P78316 NOP14_HUMAN Nucleolar protein 14 (Nucleolar complex protein 14) NOP14 C4orf9 NOL14 RES4-25 Homo sapiens (Human) "endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000480]; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000472]; maturation of SSU-rRNA [GO:0030490]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364]" 90S preribosome [GO:0030686]; membrane [GO:0016020]; Noc4p-Nop14p complex [GO:0030692]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040] enzyme binding [GO:0019899]; RNA binding [GO:0003723]; snoRNA binding [GO:0030515] 0.96922 -4.9449 KELIEELIAK 0 0 0 0 0 0 0 9.95045 0 0 9.33494 10.5723 0 0 0 0 10.502 0 7.87018 0 0 0 0 0 0 0 0 P78318 IGBP1_HUMAN Immunoglobulin-binding protein 1 (B-cell signal transduction molecule alpha 4) (Protein alpha-4) (CD79a-binding protein 1) (Protein phosphatase 2/4/6 regulatory subunit) (Renal carcinoma antigen NY-REN-16) IGBP1 IBP1 Homo sapiens (Human) B cell activation [GO:0042113]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of dephosphorylation [GO:0035303]; regulation of microtubule-based movement [GO:0060632]; response to interleukin-1 [GO:0070555]; response to tumor necrosis factor [GO:0034612]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829] protein phosphatase 2A binding [GO:0051721]; protein phosphatase regulator activity [GO:0019888] 0.65265 0.39575 AAPEEFR 0 0 0 0 0 0 0 0 0 8.24907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P78325 ADAM8_HUMAN Disintegrin and metalloproteinase domain-containing protein 8 (ADAM 8) (EC 3.4.24.-) (Cell surface antigen MS2) (CD antigen CD156a) ADAM8 MS2 Homo sapiens (Human) angiogenesis [GO:0001525]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cellular response to hypoxia [GO:0071456]; extracellular matrix disassembly [GO:0022617]; inflammatory response [GO:0006954]; leukocyte migration involved in inflammatory response [GO:0002523]; lymphocyte chemotaxis [GO:0048247]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of eosinophil migration [GO:2000418]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fibronectin-dependent thymocyte migration [GO:2000415]; positive regulation of innate immune response [GO:0045089]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein processing [GO:0010954]; positive regulation of protein secretion [GO:0050714]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; positive regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000309]; proteolysis [GO:0006508]; regulation of cell-cell adhesion [GO:0022407] alpha9-beta1 integrin-ADAM8 complex [GO:0071133]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dense core granule membrane [GO:0032127]; ficolin-1-rich granule membrane [GO:0101003]; phagolysosome [GO:0032010]; plasma membrane [GO:0005886]; podosome [GO:0002102]; specific granule [GO:0042581]; specific granule membrane [GO:0035579]; tertiary granule [GO:0070820]; tertiary granule membrane [GO:0070821] calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; protein self-association [GO:0043621]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270] 0.84032 0.17974 GEQCDCGPPEDCR 0 0 0 0 0 0 0 0 0 0 10.5691 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P78332 RBM6_HUMAN RNA-binding protein 6 (Lung cancer antigen NY-LU-12) (Protein G16) (RNA-binding motif protein 6) (RNA-binding protein DEF-3) RBM6 DEF3 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; RNA processing [GO:0006396]" nucleus [GO:0005634] DNA binding [GO:0003677]; RNA binding [GO:0003723] 0.96922 -3.5673 GSGTTDLDFR 8.35319 0 0 0 0 0 0 0 0 0 8.82158 0 0 0 0 0 0 11.0548 0 9.77609 9.05945 0 0 10.6234 0 0 11.6515 P78333 GPC5_HUMAN Glypican-5 [Cleaved into: Secreted glypican-5] GPC5 Homo sapiens (Human) cell migration [GO:0016477]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; regulation of protein localization to membrane [GO:1905475] cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; plasma membrane [GO:0005886] 0.89251 -0.51194 AGPDLQVCISKKPTCCTR 9.1894 9.88206 9.03878 0 0 0 0 0 9.024 11.4801 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P78344 IF4G2_HUMAN Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (Death-associated protein 5) (DAP-5) (p97) EIF4G2 DAP5 OK/SW-cl.75 Homo sapiens (Human) cell death [GO:0008219]; macromolecule biosynthetic process [GO:0009059]; negative regulation of autophagy [GO:0010507]; positive regulation of cell growth [GO:0030307]; regulation of cell cycle [GO:0051726]; regulation of translational initiation [GO:0006446] adherens junction [GO:0005912]; cytosol [GO:0005829]; eukaryotic translation initiation factor 4F complex [GO:0016281]; membrane [GO:0016020] "cadherin binding [GO:0045296]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; translation factor activity, RNA binding [GO:0008135]; translation initiation factor activity [GO:0003743]" 0.6956 0.37693 QEGIATSDNFMQAFLNVLDQCPK 10.4089 10.5133 10.4015 0 0 0 0 10.16 10.1067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P78347 GTF2I_HUMAN General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BAP-135) (BTK-associated protein 135) (SRF-Phox1-interacting protein) (SPIN) (Williams-Beuren syndrome chromosomal region 6 protein) GTF2I BAP135 WBSCR6 Homo sapiens (Human) negative regulation of angiogenesis [GO:0016525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; transcription by RNA polymerase II [GO:0006366] cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]" 0.93053 -1.2486 DFQKDFVK 0 0 0 0 0 0 0 0 0 8.98005 0 0 0 0 0 0 0 0 0 0 0 0 0 9.71963 0 0 0 P78348 ASIC1_HUMAN "Acid-sensing ion channel 1 (ASIC1) (Amiloride-sensitive cation channel 2, neuronal) (Brain sodium channel 2) (BNaC2)" ASIC1 ACCN2 BNAC2 Homo sapiens (Human) associative learning [GO:0008306]; behavioral fear response [GO:0001662]; calcium ion transmembrane transport [GO:0070588]; cellular response to pH [GO:0071467]; memory [GO:0007613]; negative regulation of neurotransmitter secretion [GO:0046929]; neurotransmitter secretion [GO:0007269]; protein homotrimerization [GO:0070207]; regulation of membrane potential [GO:0042391]; response to acidic pH [GO:0010447]; response to amphetamine [GO:0001975]; response to pH [GO:0009268]; sensory perception of sour taste [GO:0050915]; signal transduction [GO:0007165]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] cell surface [GO:0009986]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; presynapse [GO:0098793] acid-sensing ion channel activity [GO:0044736]; ligand-gated sodium channel activity [GO:0015280] 0.89004 -0.49833 EAKRSSADK 0 12.7822 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P78357 CNTP1_HUMAN Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (p190) CNTNAP1 CASPR NRXN4 Homo sapiens (Human) "axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128]; signal transduction [GO:0007165]" glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; paranodal junction [GO:0033010]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; presynaptic active zone [GO:0048786] SH3 domain binding [GO:0017124]; signaling receptor activity [GO:0038023] 0.93311 -1.2879 NLAYRHNFR 0 0 0 8.355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5469 0 0 0 0 0 0 P78363 ABCA4_HUMAN Retinal-specific phospholipid-transporting ATPase ABCA4 (EC 7.6.2.1) (ATP-binding cassette sub-family A member 4) (RIM ABC transporter) (RIM proteinv) (RmP) (Retinal-specific ATP-binding cassette transporter) (Stargardt disease protein) ABCA4 ABCR Homo sapiens (Human) "lipid transport [GO:0006869]; phospholipid transfer to membrane [GO:0006649]; phospholipid translocation [GO:0045332]; photoreceptor cell maintenance [GO:0045494]; phototransduction, visible light [GO:0007603]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; transmembrane transport [GO:0055085]; visual perception [GO:0007601]" cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; photoreceptor disc membrane [GO:0097381]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; rod photoreceptor disc membrane [GO:0120202] 11-cis retinal binding [GO:0005502]; ABC-type transporter activity [GO:0140359]; all-trans retinal binding [GO:0005503]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled intramembrane lipid transporter activity [GO:0140326]; ATPase-coupled transmembrane transporter activity [GO:0042626]; flippase activity [GO:0140327]; GTPase activity [GO:0003924]; N-retinylidene-phosphatidylethanolamine flippase activity [GO:0140347]; phosphatidylethanolamine flippase activity [GO:0090555]; phospholipid transporter activity [GO:0005548]; retinoid binding [GO:0005501]; retinol transmembrane transporter activity [GO:0034632] 0.96807 -3.68 GAFRCMGTIQHLKSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5348 0 0 8.46626 0 0 0 0 0 11.3951 P78367 NKX32_HUMAN Homeobox protein Nkx-3.2 (Bagpipe homeobox protein homolog 1) (Homeobox protein NK-3 homolog B) NKX3-2 BAPX1 NKX3B Homo sapiens (Human) animal organ formation [GO:0048645]; cell differentiation [GO:0030154]; determination of left/right symmetry [GO:0007368]; embryonic skeletal system development [GO:0048706]; intestinal epithelial cell development [GO:0060576]; middle ear morphogenesis [GO:0042474]; negative regulation of apoptotic process [GO:0043066]; negative regulation of chondrocyte differentiation [GO:0032331]; pancreas development [GO:0031016]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; spleen development [GO:0048536]; transcription by RNA polymerase II [GO:0006366] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.95498 -1.5676 VLVRDDQR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0966 0 0 0 0 0 0 0 0 0 0 0 0 0 P78369 CLD10_HUMAN Claudin-10 (Oligodendrocyte-specific protein-like) (OSP-like) CLDN10 Homo sapiens (Human) bicellular tight junction assembly [GO:0070830]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; monoatomic ion transport [GO:0006811]; regulation of monoatomic ion transport [GO:0043269] bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886] identical protein binding [GO:0042802]; structural molecule activity [GO:0005198] 0.25105 0.8497 VGGSDKAK 12.4759 12.3092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.21767 0 0 0 0 0 0 0 0 0 0 P78371 TCPB_HUMAN T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta) CCT2 99D8.1 CCTB Homo sapiens (Human) binding of sperm to zona pellucida [GO:0007339]; chaperone mediated protein folding independent of cofactor [GO:0051086]; chaperone-mediated protein complex assembly [GO:0051131]; chaperone-mediated protein folding [GO:0061077]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of protein localization to Cajal body [GO:1904871]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; scaRNA localization to Cajal body [GO:0090666]; toxin transport [GO:1901998] azurophil granule lumen [GO:0035578]; cell body [GO:0044297]; chaperonin-containing T-complex [GO:0005832]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; microtubule [GO:0005874]; zona pellucida receptor complex [GO:0002199] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; protein folding chaperone [GO:0044183]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082] 0 81.404 ASLSLAPVNIFK 8.98479 0 9.39099 0 0 0 10.0715 9.18148 9.43729 0 0 0 8.78441 9.08242 9.02879 9.58224 9.47023 9.09658 8.94808 9.84438 8.83102 8.92452 8.7495 8.98194 10.0111 10.1878 9.66697 P78386 KRT85_HUMAN "Keratin, type II cuticular Hb5 (Hair keratin K2.12) (Keratin-85) (K85) (Type II hair keratin Hb5) (Type-II keratin Kb25)" KRT85 KRTHB5 Homo sapiens (Human) epidermis development [GO:0008544]; keratinization [GO:0031424] cytosol [GO:0005829]; extracellular space [GO:0005615]; keratin filament [GO:0045095] structural constituent of skin epidermis [GO:0030280]; structural molecule activity [GO:0005198] 0 3.7035 ATAENEFVVLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4759 0 0 0 0 0 0 0 11.6995 0 0 P78395 PRAME_HUMAN Melanoma antigen preferentially expressed in tumors (Opa-interacting protein 4) (OIP-4) (Preferentially expressed antigen of melanoma) PRAME MAPE OIP4 Homo sapiens (Human) apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell differentiation [GO:0045596]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of retinoic acid receptor signaling pathway [GO:0048387]; positive regulation of cell population proliferation [GO:0008284]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209] chromatin [GO:0000785]; Cul2-RING ubiquitin ligase complex [GO:0031462]; cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] nuclear retinoic acid receptor binding [GO:0042974]; ubiquitin ligase-substrate adaptor activity [GO:1990756] 0.88904 -0.45194 IFAMPMQDIKMILK 0 11.0265 0 9.61298 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P78412 IRX6_HUMAN Iroquois-class homeodomain protein IRX-6 (Homeodomain protein IRXB3) (Iroquois homeobox protein 6) IRX6 IRX7 IRXB3 Homo sapiens (Human) cell development [GO:0048468]; neuron differentiation [GO:0030182]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.63161 0.40423 DSACDESSCIPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.03298 0 P78415 IRX3_HUMAN Iroquois-class homeodomain protein IRX-3 (Homeodomain protein IRXB1) (Iroquois homeobox protein 3) IRX3 IRXB1 Homo sapiens (Human) atrioventricular bundle cell differentiation [GO:0003167]; cell development [GO:0048468]; energy homeostasis [GO:0097009]; His-Purkinje system cell differentiation [GO:0060932]; mesoderm development [GO:0007498]; metanephros development [GO:0001656]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Purkinje myocyte development [GO:0003165]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of transcription by RNA polymerase II [GO:0006357]; specification of loop of Henle identity [GO:0072086] axon [GO:0030424]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.84703 0.1676 LVSAPLGK 0 0 0 0 0 0 0 0 0 9.02639 0 0 0 0 0 0 0 0 0 0 0 0 10.1854 0 0 0 0 P78423 X3CL1_HUMAN Fractalkine (C-X3-C motif chemokine 1) (CX3C membrane-anchored chemokine) (Neurotactin) (Small-inducible cytokine D1) [Cleaved into: Processed fractalkine] CX3CL1 FKN NTT SCYD1 A-152E5.2 Homo sapiens (Human) aging [GO:0007568]; angiogenesis involved in wound healing [GO:0060055]; autocrine signaling [GO:0035425]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to type II interferon [GO:0071346]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; eosinophil chemotaxis [GO:0048245]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; integrin activation [GO:0033622]; leukocyte adhesive activation [GO:0050902]; leukocyte chemotaxis [GO:0030595]; leukocyte migration involved in inflammatory response [GO:0002523]; lymphocyte chemotaxis [GO:0048247]; microglial cell activation [GO:0001774]; microglial cell proliferation [GO:0061518]; monocyte chemotaxis [GO:0002548]; negative regulation of apoptotic process [GO:0043066]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of glutamate receptor signaling pathway [GO:1900450]; negative regulation of hippocampal neuron apoptotic process [GO:0110091]; negative regulation of interleukin-1 alpha production [GO:0032690]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of neuron migration [GO:2001223]; negative regulation of tumor necrosis factor production [GO:0032720]; neuron cellular homeostasis [GO:0070050]; neuron remodeling [GO:0016322]; neutrophil chemotaxis [GO:0030593]; positive chemotaxis [GO:0050918]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of calcium-independent cell-cell adhesion [GO:0051041]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell migration [GO:1904141]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta1 production [GO:0032914]; regulation of lipopolysaccharide-mediated signaling pathway [GO:0031664]; regulation of neurogenesis [GO:0050767]; regulation of synaptic plasticity [GO:0048167]; response to ischemia [GO:0002931]; synapse pruning [GO:0098883] cell projection [GO:0042995]; cell surface [GO:0009986]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] CCR chemokine receptor binding [GO:0048020]; chemoattractant activity [GO:0042056]; chemokine activity [GO:0008009]; CX3C chemokine receptor binding [GO:0031737]; CXCR1 chemokine receptor binding [GO:0045237]; integrin binding [GO:0005178]; signaling receptor binding [GO:0005102] 0.91633 -0.76932 EPVASGSWTPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.25887 0 0 0 0 0 0 9.74012 0 0 0 P78424 PO6F2_HUMAN "POU domain, class 6, transcription factor 2 (Retina-derived POU domain factor 1) (RPF-1)" POU6F2 RPF1 Homo sapiens (Human) central nervous system development [GO:0007417]; ganglion mother cell fate determination [GO:0007402]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; visual perception [GO:0007601] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.88413 -0.13828 LNYDREVVRVWFCNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.18411 0 0 0 0 0 P78504 JAG1_HUMAN Protein jagged-1 (Jagged1) (hJ1) (CD antigen CD339) JAG1 JAGL1 Homo sapiens (Human) angiogenesis [GO:0001525]; aorta morphogenesis [GO:0035909]; aortic valve morphogenesis [GO:0003180]; blood vessel remodeling [GO:0001974]; cardiac neural crest cell development involved in outflow tract morphogenesis [GO:0061309]; cardiac right ventricle morphogenesis [GO:0003215]; cardiac septum morphogenesis [GO:0060411]; cell fate determination [GO:0001709]; ciliary body morphogenesis [GO:0061073]; distal tubule development [GO:0072017]; endocardial cushion cell development [GO:0061444]; endothelial cell differentiation [GO:0045446]; hemopoiesis [GO:0030097]; inhibition of neuroepithelial cell differentiation [GO:0002085]; inner ear auditory receptor cell differentiation [GO:0042491]; keratinocyte differentiation [GO:0030216]; loop of Henle development [GO:0072070]; morphogenesis of an epithelial sheet [GO:0002011]; myoblast differentiation [GO:0045445]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of endothelial cell differentiation [GO:0045602]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of stem cell differentiation [GO:2000737]; nephron development [GO:0072006]; nervous system development [GO:0007399]; neuroendocrine cell differentiation [GO:0061101]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; podocyte development [GO:0072015]; positive regulation of cardiac epithelial to mesenchymal transition [GO:0062043]; positive regulation of myeloid cell differentiation [GO:0045639]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pulmonary artery morphogenesis [GO:0061156]; pulmonary valve morphogenesis [GO:0003184]; regulation of cell population proliferation [GO:0042127]; regulation of epithelial cell proliferation [GO:0050678]; regulation of reproductive process [GO:2000241]; response to muramyl dipeptide [GO:0032495]; T cell mediated immunity [GO:0002456] adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; growth factor activity [GO:0008083]; molecular adaptor activity [GO:0060090]; Notch binding [GO:0005112]; phospholipid binding [GO:0005543]; structural molecule activity [GO:0005198] 0.84852 0.15682 CECAPGFAGPDCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.79476 10.7323 0 0 0 0 0 0 0 0 0 0 P78509 RELN_HUMAN Reelin (EC 3.4.21.-) RELN Homo sapiens (Human) "associative learning [GO:0008306]; axon guidance [GO:0007411]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell morphogenesis involved in differentiation [GO:0000904]; central nervous system development [GO:0007417]; cerebral cortex tangential migration [GO:0021800]; dendrite development [GO:0016358]; glial cell differentiation [GO:0010001]; hippocampus development [GO:0021766]; interneuron migration [GO:1904936]; lateral motor column neuron migration [GO:0097477]; layer formation in cerebral cortex [GO:0021819]; locomotory behavior [GO:0007626]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; modulation of chemical synaptic transmission [GO:0050804]; neuron migration [GO:0001764]; NMDA glutamate receptor clustering [GO:0097114]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of AMPA receptor activity [GO:2000969]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of lateral motor column neuron migration [GO:1902078]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of TOR signaling [GO:0032008]; postsynaptic density protein 95 clustering [GO:0097119]; protein localization to synapse [GO:0035418]; proteolysis [GO:0006508]; receptor localization to synapse [GO:0097120]; reelin-mediated signaling pathway [GO:0038026]; regulation of behavior [GO:0050795]; regulation of neuron differentiation [GO:0045664]; regulation of neuron migration [GO:2001222]; regulation of NMDA receptor activity [GO:2000310]; regulation of synaptic activity [GO:0060025]; response to pain [GO:0048265]; spinal cord patterning [GO:0021511]; ventral spinal cord development [GO:0021517]" cytoplasm [GO:0005737]; dendrite [GO:0030425]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; reelin complex [GO:0110157] lipoprotein particle receptor binding [GO:0070325]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; very-low-density lipoprotein particle receptor binding [GO:0070326] 0.96941 -4.1178 ALVFNKDGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.948 0 8.61088 0 0 0 0 9.57312 0 0 11.4842 0 9.57809 P78524 DEN2B_HUMAN DENN domain-containing protein 2B (HeLa tumor suppression 1) (Suppression of tumorigenicity 5 protein) DENND2B HTS1 ST5 Homo sapiens (Human) positive regulation of ERK1 and ERK2 cascade [GO:0070374] cell cortex [GO:0005938]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037] guanyl-nucleotide exchange factor activity [GO:0005085] 0.96418 -2.4044 GISAALVYPFMR 0 0 0 0 0 9.25394 11.0206 11.541 0 10.5075 0 0 0 9.27445 10.0428 0 10.6052 11.1839 0 0 0 0 0 0 0 0 0 P78527 PRKDC_HUMAN DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460) PRKDC HYRC HYRC1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; B cell lineage commitment [GO:0002326]; brain development [GO:0007420]; cellular response to insulin stimulus [GO:0032869]; DNA damage response [GO:0006974]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via nonhomologous end joining [GO:0006303]; ectopic germ cell programmed cell death [GO:0035234]; heart development [GO:0007507]; immature B cell differentiation [GO:0002327]; immunoglobulin V(D)J recombination [GO:0033152]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; maturation of 5.8S rRNA [GO:0000460]; mitotic G1 DNA damage checkpoint signaling [GO:0031571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of innate immune response [GO:0045824]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of apoptotic process [GO:0043065]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of lymphocyte differentiation [GO:0045621]; positive regulation of platelet formation [GO:1905221]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; pro-B cell differentiation [GO:0002328]; protein destabilization [GO:0031648]; protein modification process [GO:0036211]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of epithelial cell proliferation [GO:0050678]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of smooth muscle cell proliferation [GO:0048660]; response to gamma radiation [GO:0010332]; rhythmic process [GO:0048511]; small-subunit processome assembly [GO:0034462]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell receptor V(D)J recombination [GO:0033153]; telomere capping [GO:0016233]; telomere maintenance [GO:0000723] "chromatin [GO:0000785]; chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; DNA-dependent protein kinase complex [GO:0070418]; DNA-dependent protein kinase-DNA ligase 4 complex [GO:0005958]; membrane [GO:0016020]; nonhomologous end joining complex [GO:0070419]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; small-subunit processome [GO:0032040]; transcription regulator complex [GO:0005667]" ATP binding [GO:0005524]; DNA-dependent protein kinase activity [GO:0004677]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; molecular function inhibitor activity [GO:0140678]; protein domain specific binding [GO:0019904]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; RNA binding [GO:0003723]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; U3 snoRNA binding [GO:0034511] 0.89747 -0.67863 DFCGRCIR 10.3262 10.4134 10.3073 0 0 0 10.2508 10.1857 8.63876 10.6025 10.7319 10.7847 0 0 10.6107 0 0 10.5894 11.8377 10.7757 0 0 0 0 11.8232 12.8688 11.3902 P78536 ADA17_HUMAN Disintegrin and metalloproteinase domain-containing protein 17 (ADAM 17) (EC 3.4.24.86) (Snake venom-like protease) (TNF-alpha convertase) (TNF-alpha-converting enzyme) (CD antigen CD156b) ADAM17 CSVP TACE Homo sapiens (Human) "amyloid precursor protein catabolic process [GO:0042987]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; commissural neuron axon guidance [GO:0071679]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein processing [GO:0016485]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; response to xenobiotic stimulus [GO:0009410]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; wound healing, spreading of epidermal cells [GO:0035313]" actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886] endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902945]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124] 0.96289 -2.6627 CQEAINATCK 11.7206 0 11.2747 0 0 0 0 11.625 0 9.02832 0 0 0 9.0847 0 0 0 0 0 0 0 0 0 0 0 0 0 P78537 BL1S1_HUMAN Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC-1 subunit 1) (GCN5-like protein 1) (Protein RT14) BLOC1S1 BLOS1 GCN5L1 RT14 Homo sapiens (Human) aerobic respiration [GO:0009060]; anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; endosomal transport [GO:0016197]; lysosome localization [GO:0032418]; melanosome organization [GO:0032438]; neuron projection development [GO:0031175]; organelle transport along microtubule [GO:0072384]; peptidyl-lysine acetylation [GO:0018394]; platelet dense granule organization [GO:0060155]; regulation of endosome size [GO:0051036]; regulation of lysosome size [GO:0062196] axon cytoplasm [GO:1904115]; BLOC-1 complex [GO:0031083]; BORC complex [GO:0099078]; cytoplasmic side of lysosomal membrane [GO:0098574]; cytosol [GO:0005829]; early endosome [GO:0005769]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759] 0.84972 0.11083 TIATALEYVYKGQLQSAPS 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.44869 0 0 P78545 ELF3_HUMAN ETS-related transcription factor Elf-3 (E74-like factor 3) (Epithelial-restricted with serine box) (Epithelium-restricted Ets protein ESX) (Epithelium-specific Ets transcription factor 1) (ESE-1) ELF3 ERT ESX JEN Homo sapiens (Human) blastocyst development [GO:0001824]; cell differentiation [GO:0030154]; extracellular matrix organization [GO:0030198]; inflammatory response [GO:0006954]; mammary gland involution [GO:0060056]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.89045 -0.49441 KNSNMTYEK 0 0 0 0 9.02639 0 0 0 11.4517 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P78549 NTH_HUMAN Endonuclease III-like protein 1 (hNTH1) (EC 3.2.2.-) (EC 4.2.99.18) (Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase) (DNA glycosylase/AP lyase) NTHL1 NTH1 OCTS3 Homo sapiens (Human) "base-excision repair, AP site formation [GO:0006285]; depyrimidination [GO:0045008]; nucleotide-excision repair [GO:0006289]" mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "4 iron, 4 sulfur cluster binding [GO:0051539]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA N-glycosylase activity [GO:0019104]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; double-stranded DNA binding [GO:0003690]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity [GO:0000703]" 0.88558 -0.29127 SLGPGAGPRGCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3644 0 0 0 0 0 0 0 P78552 I13R1_HUMAN Interleukin-13 receptor subunit alpha-1 (IL-13 receptor subunit alpha-1) (IL-13R subunit alpha-1) (IL-13R-alpha-1) (IL-13RA1) (Cancer/testis antigen 19) (CT19) (CD antigen CD213a1) IL13RA1 IL13R IL13RA Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221] external side of plasma membrane [GO:0009897]; interleukin-13 receptor complex [GO:0005898]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896] 0.90947 -0.74488 IKPSFNIVPLTSR 0 0 0 10.0462 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.4678 0 0 P78559 MAP1A_HUMAN Microtubule-associated protein 1A (MAP-1A) (Proliferation-related protein p80) [Cleaved into: MAP1A heavy chain; MAP1 light chain LC2] MAP1A MAP1L Homo sapiens (Human) anterograde axonal protein transport [GO:0099641]; associative learning [GO:0008306]; axonogenesis [GO:0007409]; dendrite development [GO:0016358]; memory [GO:0007613]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein localization to microtubule [GO:1902817]; neuron cellular homeostasis [GO:0070050]; neuron projection maintenance [GO:1990535]; positive regulation of protein localization [GO:1903829]; positive regulation of protein localization to cell surface [GO:2000010]; regulation of microtubule depolymerization [GO:0031114]; regulation of synaptic plasticity [GO:0048167]; retrograde axonal protein transport [GO:0099642]; voluntary musculoskeletal movement [GO:0050882] axon [GO:0030424]; axon cytoplasm [GO:1904115]; axon initial segment [GO:0043194]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic branch [GO:0044307]; dendritic microtubule [GO:1901588]; dendritic shaft [GO:0043198]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; primary dendrite [GO:0150001]; synapse [GO:0045202] actin binding [GO:0003779]; cytoskeletal anchor activity [GO:0008093]; microtubule binding [GO:0008017]; structural molecule activity [GO:0005198]; tau protein binding [GO:0048156]; tubulin binding [GO:0015631] 0.96876 -8.5317 ALALAPGPPTRTR 0 0 0 9.15135 0 0 8.76414 8.77952 8.73806 0 11.9066 16.4828 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.97091 P80303 NUCB2_HUMAN Nucleobindin-2 (DNA-binding protein NEFA) (Epididymis secretory protein Li 109) (Gastric cancer antigen Zg4) (Prepronesfatin) [Cleaved into: Nesfatin-1] NUCB2 NEFA Homo sapiens (Human) small GTPase mediated signal transduction [GO:0007264] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; G-protein alpha-subunit binding [GO:0001965]; guanyl-nucleotide exchange factor activity [GO:0005085] 0.91336 -0.75331 AATSDLEHYDK 0 0 10.689 10.9699 11.2212 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3203 9.57495 0 0 0 0 0 0 0 P80365 DHI2_HUMAN 11-beta-hydroxysteroid dehydrogenase type 2 (11-DH2) (11-beta-HSD2) (EC 1.1.1.-) (11-beta-hydroxysteroid dehydrogenase type II) (11-HSD type II) (11-beta-HSD type II) (Corticosteroid 11-beta-dehydrogenase isozyme 2) (NAD-dependent 11-beta-hydroxysteroid dehydrogenase) (Short chain dehydrogenase/reductase family 9C member 3) HSD11B2 HSD11K SDR9C3 Homo sapiens (Human) cortisol metabolic process [GO:0034650]; female pregnancy [GO:0007565]; glucocorticoid metabolic process [GO:0008211]; regulation of blood volume by renal aldosterone [GO:0002017]; response to food [GO:0032094]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to insulin [GO:0032868]; response to xenobiotic stimulus [GO:0009410] endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231] 11-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0070523]; NAD binding [GO:0051287]; steroid binding [GO:0005496] 0.86402 0.081535 FLQAFFISHCLPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0791 0 0 0 0 P80370 DLK1_HUMAN Protein delta homolog 1 (DLK-1) (pG2) [Cleaved into: Fetal antigen 1 (FA1)] DLK1 DLK Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of Notch signaling pathway [GO:0045746] cytoplasm [GO:0005737]; extracellular space [GO:0005615]; membrane [GO:0016020] calcium ion binding [GO:0005509] 0.36594 0.744 KNLLLQYNSGEDLAVNIIFPEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.19749 0 0 0 0 P81133 SIM1_HUMAN Single-minded homolog 1 (Class E basic helix-loop-helix protein 14) (bHLHe14) SIM1 BHLHE14 Homo sapiens (Human) cell differentiation [GO:0030154]; nervous system development [GO:0007399]; regulation of transcription by RNA polymerase II [GO:0006357]; ureteric bud development [GO:0001657] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.96947 -6.5098 GQVTTKYYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.28341 0 0 8.37613 0 0 9.55455 10.6121 10.0304 0 0 0 0 P81274 GPSM2_HUMAN G-protein-signaling modulator 2 (Mosaic protein LGN) GPSM2 LGN Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] cell cortex [GO:0005938]; cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lateral cell cortex [GO:0097575]; lateral plasma membrane [GO:0016328]; mitotic spindle pole [GO:0097431]; protein-containing complex [GO:0032991] dynein complex binding [GO:0070840]; G-protein alpha-subunit binding [GO:0001965]; GDP-dissociation inhibitor activity [GO:0005092]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]; protein domain specific binding [GO:0019904]; protein self-association [GO:0043621] 0.95064 -1.4061 MEENLISMREDHSFHVRYR 0 9.18777 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P81277 PRRP_HUMAN Prolactin-releasing peptide (PrRP) (Prolactin-releasing hormone) [Cleaved into: Prolactin-releasing peptide PrRP31; Prolactin-releasing peptide PrRP20] PRLH PRH Homo sapiens (Human) autonomic nervous system development [GO:0048483]; energy reserve metabolic process [GO:0006112]; fat cell differentiation [GO:0045444]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; lipid metabolic process [GO:0006629]; reduction of food intake in response to dietary excess [GO:0002023]; regulation of multicellular organism growth [GO:0040014]; response to glucose [GO:0009749]; response to insulin [GO:0032868]; response to peptide hormone [GO:0043434]; tissue homeostasis [GO:0001894] cytoplasm [GO:0005737]; extracellular region [GO:0005576] hormone activity [GO:0005179]; neuropeptide hormone activity [GO:0005184]; prolactin-releasing peptide receptor binding [GO:0031861] 0.9551 -1.5791 GAASRTHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2514 P81408 EREP3_HUMAN Protein ENTREP3 (Endosomal transmembrane epsin interactor 3) (Protein COTE1) ENTREP3 C1orf2 COTE1 FAM189B Homo sapiens (Human) membrane [GO:0016020] WW domain binding [GO:0050699] 0.91427 -0.79612 NAQLARDFQQCSLEGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2746 0 0 0 0 0 0 0 P81605 DCD_HUMAN Dermcidin (EC 3.4.-.-) (Preproteolysin) [Cleaved into: Survival-promoting peptide; DCD-1] DCD AIDD DSEP Homo sapiens (Human) antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inorganic anion transport [GO:0015698]; killing by host of symbiont cells [GO:0051873]; killing of cells of another organism [GO:0031640]; proteolysis [GO:0006508] extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; pore complex [GO:0046930] metal ion binding [GO:0046872]; monoatomic anion channel activity [GO:0005253]; peptidase activity [GO:0008233]; RNA binding [GO:0003723] 0 5.8542 DAVEDLESVGK 9.85295 8.77498 0 0 0 0 10.6215 10.6819 10.7649 0 9.29354 9.08332 0 0 0 0 0 0 9.7354 0 0 0 0 0 0 0 9.66686 P82094 TMF1_HUMAN TATA element modulatory factor (TMF) (Androgen receptor coactivator 160 kDa protein) (Androgen receptor-associated protein of 160 kDa) TMF1 ARA160 Homo sapiens (Human) acrosome assembly [GO:0001675]; androgen receptor signaling pathway [GO:0030521]; defense response to bacterium [GO:0042742]; epithelial cell apoptotic process [GO:1904019]; flagellated sperm motility [GO:0030317]; Leydig cell differentiation [GO:0033327]; luteinizing hormone secretion [GO:0032275]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of gene expression [GO:0010629]; positive regulation of cytokine production [GO:0001819]; positive regulation of testosterone secretion [GO:2000845]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of proteasomal protein catabolic process [GO:0061136]; spermatid nucleus differentiation [GO:0007289] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleus [GO:0005634] DNA binding [GO:0003677]; nuclear androgen receptor binding [GO:0050681]; nuclear receptor coactivator activity [GO:0030374] 0.954 -1.5255 AEEAEELR 0 0 0 9.87584 0 0 0 10.9427 0 9.00876 0 0 0 0 9.43219 10.3706 0 0 0 0 0 0 0 0 12.1944 0 0 P82251 BAT1_HUMAN "b(0,+)-type amino acid transporter 1 (b(0,+)AT1) (Glycoprotein-associated amino acid transporter b0,+AT1) (Solute carrier family 7 member 9)" SLC7A9 BAT1 Homo sapiens (Human) amino acid transmembrane transport [GO:0003333]; L-cystine transport [GO:0015811]; neutral amino acid transport [GO:0015804]; protein-containing complex assembly [GO:0065003] apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; plasma membrane [GO:0005886] antiporter activity [GO:0015297]; L-cystine transmembrane transporter activity [GO:0015184]; neutral L-amino acid transmembrane transporter activity [GO:0015175]; peptide antigen binding [GO:0042605]; protein heterodimerization activity [GO:0046982] 0.9165 -0.76573 LIYVAGREGHMLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.70627 0 P82279 CRUM1_HUMAN Protein crumbs homolog 1 CRB1 Homo sapiens (Human) blood vessel remodeling [GO:0001974]; cell-cell signaling [GO:0007267]; cellular response to light stimulus [GO:0071482]; detection of light stimulus involved in visual perception [GO:0050908]; establishment of bipolar cell polarity involved in cell morphogenesis [GO:0061159]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; eye photoreceptor cell development [GO:0042462]; gene expression [GO:0010467]; glial cell differentiation [GO:0010001]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; photoreceptor cell maintenance [GO:0045494]; photoreceptor cell outer segment organization [GO:0035845]; plasma membrane organization [GO:0007009]; post-embryonic retina morphogenesis in camera-type eye [GO:0060060]; protein localization [GO:0008104]; retina layer formation [GO:0010842] adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical plasma membrane [GO:0016324]; extracellular region [GO:0005576]; glial cell projection [GO:0097386]; microvillus [GO:0005902]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; subapical complex [GO:0035003] calcium ion binding [GO:0005509] 0.89875 -0.64416 FCRQSRLPSTVCGNEK 0 0 0 0 0 0 0 0 10.5723 9.7655 12.2787 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P82650 RT22_HUMAN "Small ribosomal subunit protein mS22 (28S ribosomal protein S22, mitochondrial) (MRP-S22) (S22mt)" MRPS22 C3orf5 RPMS22 GK002 Homo sapiens (Human) mitochondrial translation [GO:0032543] mitochondrial inner membrane [GO:0005743]; mitochondrial ribosome [GO:0005761]; mitochondrial small ribosomal subunit [GO:0005763]; mitochondrion [GO:0005739] structural constituent of ribosome [GO:0003735] 0.96237 -2.496 EPSGTLRKASWEER 0 0 0 0 0 0 10.8107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.56468 9.26552 0 0 0 P82664 RT10_HUMAN "Small ribosomal subunit protein uS10m (28S ribosomal protein S10, mitochondrial) (MRP-S10) (S10mt)" MRPS10 MSTP040 Homo sapiens (Human) mitochondrial translation [GO:0032543] mitochondrial inner membrane [GO:0005743]; mitochondrial small ribosomal subunit [GO:0005763]; mitochondrion [GO:0005739] 0.95979 -1.9808 RLSVLVKGHDK 0 0 0 0 0 0 0 0 0 0 0 0 9.46769 0 0 0 0 10.1495 0 0 0 0 0 0 0 0 0 P82673 RT35_HUMAN "Small ribosomal subunit protein mS35 (28S ribosomal protein S28, mitochondrial) (MRP-S28) (S28mt) (28S ribosomal protein S35, mitochondrial) (MRP-S35) (S35mt)" MRPS35 MRPS28 HDCMD11P MDS023 PSEC0213 Homo sapiens (Human) mitochondrial translation [GO:0032543] mitochondrial inner membrane [GO:0005743]; mitochondrial small ribosomal subunit [GO:0005763] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.93314 -1.2654 LIKLVGERYCK 0 0 0 0 0 0 0 0 0 0 0 0 9.71697 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P82914 RT15_HUMAN "Small ribosomal subunit protein uS15m (28S ribosomal protein S15, mitochondrial) (MRP-S15) (S15mt)" MRPS15 RPMS15 DC37 Homo sapiens (Human) mitochondrial translation [GO:0032543]; translation [GO:0006412] mitochondrial inner membrane [GO:0005743]; mitochondrial small ribosomal subunit [GO:0005763]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.96937 -4.4714 AAAAAQK 0 0 0 0 0 0 0 0 0 0 12.5451 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P82921 RT21_HUMAN "Small ribosomal subunit protein bS21m (28S ribosomal protein S21, mitochondrial) (MRP-S21) (S21mt)" MRPS21 RPMS21 MDS016 Homo sapiens (Human) mitochondrial translation [GO:0032543]; translation [GO:0006412] mitochondrial inner membrane [GO:0005743]; mitochondrial small ribosomal subunit [GO:0005763] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.91481 -0.78108 IYNMEMARK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.46375 0 0 0 P82930 RT34_HUMAN "Small ribosomal subunit protein mS34 (28S ribosomal protein S34, mitochondrial) (MRP-S34) (S34mt)" MRPS34 Homo sapiens (Human) mitochondrial translation [GO:0032543] mitochondrial inner membrane [GO:0005743]; mitochondrial small ribosomal subunit [GO:0005763]; mitochondrion [GO:0005739] structural constituent of ribosome [GO:0003735] 0.80026 0.23911 EIEHVMYHDWR 0 0 0 0 0 0 0 0 9.66757 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P82933 RT09_HUMAN "Small ribosomal subunit protein uS9m (28S ribosomal protein S9, mitochondrial) (MRP-S9) (S9mt)" MRPS9 RPMS9 Homo sapiens (Human) mitochondrial translation [GO:0032543] mitochondrial inner membrane [GO:0005743]; mitochondrial small ribosomal subunit [GO:0005763]; mitochondrion [GO:0005739]; nucleolus [GO:0005730] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.95822 -1.8682 HTAFVIPKKNVPTSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.72339 0 0 0 0 0 P82987 ATL3_HUMAN ADAMTS-like protein 3 (ADAMTSL-3) (Punctin-2) ADAMTSL3 KIAA1233 Homo sapiens (Human) extracellular matrix organization [GO:0030198] extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231] 0.95548 -1.6352 EENVIAVPLGSRSVRITVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.67583 0 0 0 0 0 10.3217 0 0 0 0 0 0 P83110 HTRA3_HUMAN Serine protease HTRA3 (EC 3.4.21.-) (High-temperature requirement factor A3) (Pregnancy-related serine protease) HTRA3 PRSP Homo sapiens (Human) negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; proteolysis [GO:0006508] extracellular region [GO:0005576] endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236] 0.89702 -0.52512 QIKDWKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.60008 P83111 LACTB_HUMAN "Serine beta-lactamase-like protein LACTB, mitochondrial (EC 3.4.-.-)" LACTB MRPL56 UNQ843/PRO1781 Homo sapiens (Human) lipid metabolic process [GO:0006629]; proteolysis [GO:0006508]; regulation of lipid metabolic process [GO:0019216] cytosol [GO:0005829]; mitochondrion [GO:0005739] identical protein binding [GO:0042802]; peptidase activity [GO:0008233] 0.92016 -0.93163 AYKALKMMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3522 0 P83436 COG7_HUMAN Conserved oligomeric Golgi complex subunit 7 (COG complex subunit 7) (Component of oligomeric Golgi complex 7) COG7 UNQ3082/PRO10013 Homo sapiens (Human) "glycosylation [GO:0070085]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; protein glycosylation [GO:0006486]; protein localization to Golgi apparatus [GO:0034067]; protein localization to organelle [GO:0033365]; protein stabilization [GO:0050821]; retrograde transport, vesicle recycling within Golgi [GO:0000301]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]" Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; intracellular membrane-bounded organelle [GO:0043231]; nucleolus [GO:0005730]; trans-Golgi network membrane [GO:0032588] 0.8513 0.16135 FTNGLGTCGLLSALK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.86372 0 P83731 RL24_HUMAN Large ribosomal subunit protein eL24 (60S ribosomal protein L24) (60S ribosomal protein L30) RPL24 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; polysomal ribosome [GO:0042788] cadherin binding [GO:0045296]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0 3.0026 AITGASLADIMAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.18192 0 0 0 0 9.92551 0 10.8234 0 0 P83859 OX26_HUMAN Orexigenic neuropeptide QRFP (P518) [Cleaved into: QRF-amide (Neuropeptide RF-amide) (Pyroglutamylated arginine-phenylalanine-amide peptide)] QRFP Homo sapiens (Human) grooming behavior [GO:0007625]; locomotory behavior [GO:0007626]; neuropeptide signaling pathway [GO:0007218]; positive regulation of blood pressure [GO:0045777]; regulation of feeding behavior [GO:0060259] extracellular region [GO:0005576] neuropeptide hormone activity [GO:0005184]; orexigenic neuropeptide QRFP receptor binding [GO:0031854] 0.91458 -0.81663 REPTDAMGGLGAGER 9.01848 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P84074 HPCA_HUMAN Neuron-specific calcium-binding protein hippocalcin (Calcium-binding protein BDR-2) HPCA BDR2 Homo sapiens (Human) activation of phospholipase D activity [GO:0031584]; brain development [GO:0007420]; calcium-mediated signaling [GO:0019722]; cellular response to calcium ion [GO:0071277]; cellular response to electrical stimulus [GO:0071257]; cellular response to L-glutamate [GO:1905232]; inner ear development [GO:0048839]; negative regulation of guanylate cyclase activity [GO:0031283]; positive regulation of adenylate cyclase activity [GO:0045762]; positive regulation of protein targeting to membrane [GO:0090314]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to Aroclor 1254 [GO:1904010]; response to ketamine [GO:1901986]; retina development in camera-type eye [GO:0060041] axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dendrite membrane [GO:0032590]; dendritic spine head [GO:0044327]; extrinsic component of membrane [GO:0019898]; glutamatergic synapse [GO:0098978]; neuronal cell body membrane [GO:0032809]; perikaryon [GO:0043204] actin binding [GO:0003779]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; kinase binding [GO:0019900] 0.8712 0.028435 ENTEFSELELQEWYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3809 0 0 0 0 0 0 0 0 0 0 P84090 ERH_HUMAN Enhancer of rudimentary homolog ERH Homo sapiens (Human) cell cycle [GO:0007049]; nucleobase-containing compound metabolic process [GO:0006139]; pyrimidine nucleoside metabolic process [GO:0006213] methylosome [GO:0034709]; midbody [GO:0030496]; nucleus [GO:0005634] methyl-CpG binding [GO:0008327]; RNA binding [GO:0003723] 0 4.6817 SHTILLVQPTK 0 0 8.57577 0 0 0 8.69589 8.99413 9.09932 9.23211 9.38115 9.34323 8.59455 9.02273 9.09658 9.78794 9.93555 9.5195 8.98832 8.8197 0 0 0 0 10.4024 10.1557 10.1555 P84095 RHOG_HUMAN Rho-related GTP-binding protein RhoG RHOG ARHG Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; activation of GTPase activity [GO:0090630]; cell chemotaxis [GO:0060326]; cortical cytoskeleton organization [GO:0030865]; establishment or maintenance of cell polarity [GO:0007163]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein localization to plasma membrane [GO:1903078]; Rac protein signal transduction [GO:0016601]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of ruffle assembly [GO:1900027]; Rho protein signal transduction [GO:0007266] cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasmic vesicle [GO:0031410]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein kinase binding [GO:0019901] 0.91475 -0.78438 AVLNPTPIKR 0 0 0 0 8.64512 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2239 9.92967 9.76759 0 0 0 0 0 0 P84098 RL19_HUMAN Large ribosomal subunit protein eL19 (60S ribosomal protein L19) RPL19 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleolus [GO:0005730]; polysomal ribosome [GO:0042788]; synapse [GO:0045202] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.0082418 2.1563 HMYHSLYLK 0 10.0034 0 0 0 0 0 0 10.51 0 9.67329 0 0 0 0 0 0 0 0 0 0 0 10.157 0 0 12.5669 0 P84101 SERF2_HUMAN Small EDRK-rich factor 2 (Gastric cancer-related protein VRG107) (Protein 4F5-related) (4F5rel) (h4F5rel) SERF2 FAM2C Homo sapiens (Human) protein destabilization [GO:0031648] cytosol [GO:0005829]; nucleus [GO:0005634] 0.96234 -2.5383 DSEIMQQKQKK 0 0 0 0 0 0 0 9.47549 0 10.4008 10.3717 0 0 0 0 0 0 0 0 0 0 0 0 9.76598 0 0 0 P84103 SRSF3_HUMAN "Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Splicing factor, arginine/serine-rich 3)" SRSF3 SFRS3 SRP20 Homo sapiens (Human) "cellular response to leukemia inhibitory factor [GO:1990830]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; primary miRNA processing [GO:0031053]; regulation of mRNA splicing, via spliceosome [GO:0048024]" cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654] phospholipase binding [GO:0043274]; primary miRNA binding [GO:0070878]; RNA binding [GO:0003723] 0.884 -0.16837 AFGYYGPLR 0 0 0 0 0 0 0 0 0 0 0 0 10.1483 0 0 9.8487 0 0 9.37141 0 0 0 9.09643 0 0 0 0 P84550 SKOR1_HUMAN SKI family transcriptional corepressor 1 (Functional Smad-suppressing element on chromosome 15) (Fussel-15) (LBX1 corepressor 1) (Ladybird homeobox corepressor 1) SKOR1 CORL1 FUSSEL15 LBXCOR1 Homo sapiens (Human) negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] dendrite [GO:0030425]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]; SMAD binding [GO:0046332]" 0.95957 -1.8221 CGYCSMYFSPNK 10.4505 0 0 0 0 0 0 0 0 0 0 0 9.25819 0 12.3533 0 0 0 0 0 0 0 0 0 0 0 0 P84996 ALEX_HUMAN Protein ALEX (Alternative gene product encoded by XL-exon) GNAS GNAS1 Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; bone development [GO:0060348]; cognition [GO:0050890]; developmental growth [GO:0048589]; hair follicle placode formation [GO:0060789]; platelet aggregation [GO:0070527]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of signal transduction [GO:0009966] cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ruffle [GO:0001726] 0.84863 0.12448 QTQGLPLPQPLLPPGQPK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.51294 0 9.71529 0 0 0 0 0 0 0 0 0 0 0 P85298 RHG08_HUMAN Rho GTPase-activating protein 8 (Rho-type GTPase-activating protein 8) ARHGAP8 Homo sapiens (Human) negative regulation of endocytic recycling [GO:2001136]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264] cytoplasm [GO:0005737]; cytosol [GO:0005829] GTPase activator activity [GO:0005096] 0.88535 -0.33785 VTGCRQILR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.63281 0 0 0 0 0 P86397 HTD2_HUMAN "Hydroxyacyl-thioester dehydratase type 2, mitochondrial (HsHTD2) (EC 4.2.1.59) (3-hydroxyacyl-[acyl-carrier-protein] dehydratase)" HTD2 Homo sapiens (Human) fatty acid biosynthetic process [GO:0006633]; fatty-acyl-CoA biosynthetic process [GO:0046949] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730] (3R)-3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity [GO:0019171]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyacyl-CoA dehydratase activity [GO:0018812] 0.83556 0.19216 TVMEGWVK 0 0 0 0 0 8.96685 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P86452 ZBED6_HUMAN Zinc finger BED domain-containing protein 6 ZBED6 Homo sapiens (Human) blastocyst hatching [GO:0001835]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of muscle cell differentiation [GO:0051148]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; regulation of transcription by RNA polymerase II [GO:0006357] centriolar satellite [GO:0034451]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]; transcription cis-regulatory region binding [GO:0000976]" 0.92723 -1.2176 AVPQLYDCVR 0 0 0 0 0 0 0 10.7187 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P86791 CCZ1_HUMAN Vacuolar fusion protein CCZ1 homolog CCZ1 C7orf28A CGI-43 Homo sapiens (Human) vesicle-mediated transport [GO:0016192] cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; Mon1-Ccz1 complex [GO:0035658] guanyl-nucleotide exchange factor activity [GO:0005085] 0.84521 0.1537 IQSFINR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0786 0 0 0 0 0 0 0 0 0 P98073 ENTK_HUMAN Enteropeptidase (EC 3.4.21.9) (Enterokinase) (Serine protease 7) (Transmembrane protease serine 15) [Cleaved into: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain] TMPRSS15 ENTK PRSS7 Homo sapiens (Human) proteolysis [GO:0006508] brush border [GO:0005903]; membrane [GO:0016020] scavenger receptor activity [GO:0005044]; serine-type endopeptidase activity [GO:0004252] 0.88762 -0.35207 CALPNRPGVYAR 0 0 0 12.1748 0 0 0 10.3002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P98077 SHC2_HUMAN SHC-transforming protein 2 (Protein Sck) (SHC-transforming protein B) (Src homology 2 domain-containing-transforming protein C2) (SH2 domain protein C2) SHC2 SCK SHCB Homo sapiens (Human) intracellular signal transduction [GO:0035556]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] cytosol [GO:0005829]; plasma membrane [GO:0005886] receptor tyrosine kinase binding [GO:0030971] 0.85612 0.10406 CAAPCPLPALSRCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.94386 0 0 0 0 0 0 0 0 P98088 MUC5A_HUMAN "Mucin-5AC (MUC-5AC) (Gastric mucin) (Major airway glycoprotein) (Mucin-5 subtype AC, tracheobronchial) (Tracheobronchial mucin) (TBM)" MUC5AC MUC5 Homo sapiens (Human) phosphatidylinositol-mediated signaling [GO:0048015] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; mucus layer [GO:0070701]; plasma membrane [GO:0005886] extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872] 0.96946 -5.5821 CLGPHGEPVK 8.46442 0 0 0 0 0 0 0 0 0 8.3594 0 0 0 0 0 10.2788 0 10.2613 9.25965 0 9.49221 0 0 10.2161 9.82254 0 P98095 FBLN2_HUMAN Fibulin-2 (FIBL-2) FBLN2 Homo sapiens (Human) positive regulation of cell-substrate adhesion [GO:0010811] collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular vesicle [GO:1903561] calcium ion binding [GO:0005509]; extracellular matrix binding [GO:0050840]; extracellular matrix constituent conferring elasticity [GO:0030023]; extracellular matrix structural constituent [GO:0005201] 0.87236 0.03702 CVDVNECETGVHR 0 0 0 0 0 0 0 0 0 0 11.7077 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P98155 VLDLR_HUMAN Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R) VLDLR Homo sapiens (Human) cholesterol metabolic process [GO:0008203]; dendrite morphogenesis [GO:0048813]; glycoprotein transport [GO:0034436]; lipid transport [GO:0006869]; memory [GO:0007613]; nervous system development [GO:0007399]; positive regulation of dendrite development [GO:1900006]; positive regulation of protein kinase activity [GO:0045860]; receptor-mediated endocytosis [GO:0006898]; reelin-mediated signaling pathway [GO:0038026]; signal transduction [GO:0007165]; ventral spinal cord development [GO:0021517]; very-low-density lipoprotein particle clearance [GO:0034447] clathrin-coated pit [GO:0005905]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; very-low-density lipoprotein particle [GO:0034361] apolipoprotein binding [GO:0034185]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; cargo receptor activity [GO:0038024]; low-density lipoprotein particle receptor activity [GO:0005041]; reelin receptor activity [GO:0038025]; very-low-density lipoprotein particle binding [GO:0034189]; very-low-density lipoprotein particle receptor activity [GO:0030229] 0.32471 0.78473 LFWADLSQK 0 0 0 11.3286 0 0 0 0 0 0 0 0 0 0 0 0 0 9.92566 0 0 0 0 0 0 10.3932 9.9209 0 P98160 PGBM_HUMAN Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) (Perlecan) (PLC) [Cleaved into: Endorepellin; LG3 peptide] HSPG2 Homo sapiens (Human) angiogenesis [GO:0001525]; brain development [GO:0007420]; cell differentiation [GO:0030154]; circulatory system development [GO:0072359]; inflammatory response [GO:0006954]; lipid metabolic process [GO:0006629]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell death [GO:0060548]; receptor-mediated endocytosis [GO:0006898] basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi lumen [GO:0005796]; lysosomal lumen [GO:0043202]; plasma membrane [GO:0005886]; plasma membrane protein complex [GO:0098797] amyloid-beta binding [GO:0001540]; calcium ion binding [GO:0005509]; extracellular matrix structural constituent conferring compression resistance [GO:0030021]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750] 0.88775 -0.39662 AVLHVHGGGGPR 11.1141 11.956 11.0017 0 10.5681 0 10.7005 10.9812 0 9.10599 0 0 0 0 0 0 0 0 9.94272 14.5901 0 0 9.38804 0 11.4079 0 11.8995 P98161 PKD1_HUMAN Polycystin-1 (PC1) (Autosomal dominant polycystic kidney disease 1 protein) PKD1 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; branching morphogenesis of an epithelial tube [GO:0048754]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; calcium-independent cell-matrix adhesion [GO:0007161]; cartilage condensation [GO:0001502]; cartilage development [GO:0051216]; cell-cell signaling by wnt [GO:0198738]; cell-matrix adhesion [GO:0007160]; cytoplasmic sequestering of transcription factor [GO:0042994]; detection of mechanical stimulus [GO:0050982]; digestive tract development [GO:0048565]; embryonic placenta development [GO:0001892]; establishment of epithelial cell polarity [GO:0090162]; genitalia development [GO:0048806]; heart development [GO:0007507]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; liver development [GO:0001889]; lung epithelium development [GO:0060428]; lymph vessel morphogenesis [GO:0036303]; mesonephric duct development [GO:0072177]; mesonephric tubule development [GO:0072164]; metanephric ascending thin limb development [GO:0072218]; metanephric collecting duct development [GO:0072205]; metanephric distal tubule morphogenesis [GO:0072287]; metanephric proximal tubule development [GO:0072237]; neural tube development [GO:0021915]; peptidyl-serine phosphorylation [GO:0018105]; placenta blood vessel development [GO:0060674]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein export from nucleus [GO:0006611]; protein heterotetramerization [GO:0051290]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of cell adhesion [GO:0030155]; regulation of cell cycle [GO:0051726]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic spindle organization [GO:0060236]; regulation of proteasomal protein catabolic process [GO:0061136]; response to fluid shear stress [GO:0034405]; skin development [GO:0043588]; spinal cord development [GO:0021510] basolateral plasma membrane [GO:0016323]; calcium channel complex [GO:0034704]; cation channel complex [GO:0034703]; cell surface [GO:0009986]; ciliary membrane [GO:0060170]; cilium [GO:0005929]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle membrane [GO:0030660]; lateral plasma membrane [GO:0016328]; membrane [GO:0016020]; motile cilium [GO:0031514]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; polycystin complex [GO:0002133] calcium channel activity [GO:0005262]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; transmembrane transporter binding [GO:0044325]; Wnt receptor activity [GO:0042813] 0.96367 -2.249 AHYFTSICVEPEVGNVTLQPER 0 0 11.3889 0 0 0 0 0 0 0 0 0 10.3038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P98164 LRP2_HUMAN Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin) LRP2 Homo sapiens (Human) amyloid-beta clearance [GO:0097242]; aorta development [GO:0035904]; cell population proliferation [GO:0008283]; cellular response to growth factor stimulus [GO:0071363]; cobalamin transport [GO:0015889]; coronary artery morphogenesis [GO:0060982]; diol metabolic process [GO:0034311]; endocytosis [GO:0006897]; folate import across plasma membrane [GO:1904447]; forebrain development [GO:0030900]; kidney development [GO:0001822]; lipid metabolic process [GO:0006629]; male gonad development [GO:0008584]; metal ion transport [GO:0030001]; negative regulation of apoptotic process [GO:0043066]; negative regulation of BMP signaling pathway [GO:0030514]; neural tube closure [GO:0001843]; neuron projection arborization [GO:0140058]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of neurogenesis [GO:0050769]; positive regulation of oligodendrocyte progenitor proliferation [GO:0070447]; positive regulation of protein kinase B signaling [GO:0051897]; protein transport [GO:0015031]; pulmonary artery morphogenesis [GO:0061156]; receptor-mediated endocytosis [GO:0006898]; response to leptin [GO:0044321]; retinoid metabolic process [GO:0001523]; secondary heart field specification [GO:0003139]; sensory perception of sound [GO:0007605]; transcytosis [GO:0045056]; transport across blood-brain barrier [GO:0150104]; vagina development [GO:0060068]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular septum development [GO:0003281]; vitamin D metabolic process [GO:0042359] apical plasma membrane [GO:0016324]; axon [GO:0030424]; brush border membrane [GO:0031526]; clathrin-coated endocytic vesicle membrane [GO:0030669]; clathrin-coated pit [GO:0005905]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; endosome lumen [GO:0031904]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] calcium ion binding [GO:0005509]; cargo receptor activity [GO:0038024]; hormone binding [GO:0042562]; insulin-like growth factor I binding [GO:0031994]; low-density lipoprotein particle receptor activity [GO:0005041]; protein transporter activity [GO:0140318]; protein-folding chaperone binding [GO:0051087]; SH3 domain binding [GO:0017124] 0.9694 -4.9735 AYIGRVGMDGTNK 10.2924 0 0 9.13188 0 0 0 0 0 0 0 0 10.7096 0 0 0 0 0 0 10.8361 0 0 0 0 0 0 0 P98171 RHG04_HUMAN Rho GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (Rho-type GTPase-activating protein 4) (p115) ARHGAP4 KIAA0131 RGC1 RHOGAP4 Homo sapiens (Human) cytoskeleton organization [GO:0007010]; negative regulation of axon extension [GO:0030517]; negative regulation of cell migration [GO:0030336]; negative regulation of fibroblast migration [GO:0010764]; nervous system development [GO:0007399]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266] cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; microtubule [GO:0005874]; nucleoplasm [GO:0005654] GTPase activator activity [GO:0005096]; identical protein binding [GO:0042802] 0.9197 -0.90667 ERGLQAEYETQVKEMR 0 0 0 0 0 0 0 0 9.3649 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P98172 EFNB1_HUMAN Ephrin-B1 (EFL-3) (ELK ligand) (ELK-L) (EPH-related receptor tyrosine kinase ligand 2) (LERK-2) [Cleaved into: Ephrin-B1 C-terminal fragment (Ephrin-B1 CTF); Ephrin-B1 intracellular domain (Ephrin-B1 ICD)] EFNB1 EFL3 EPLG2 LERK2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; embryonic pattern specification [GO:0009880]; ephrin receptor signaling pathway [GO:0048013]; neural crest cell migration [GO:0001755]; positive regulation of T cell proliferation [GO:0042102]; regulation of autophagosome assembly [GO:2000785]; T cell costimulation [GO:0031295]; T cell proliferation [GO:0042098] cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202] ephrin receptor binding [GO:0046875]; ubiquitin-protein transferase activator activity [GO:0097027] 0.8202 0.21693 TTENNYCPHYEK 0 0 0 0 0 0 0 0 0 9.12959 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P98174 FGD1_HUMAN "FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF) (Zinc finger FYVE domain-containing protein 3)" FGD1 FGDY ZFYVE3 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; animal organ morphogenesis [GO:0009887]; cytoskeleton organization [GO:0007010]; filopodium assembly [GO:0046847]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; lamellipodium [GO:0030027]; ruffle [GO:0001726] guanyl-nucleotide exchange factor activity [GO:0005085]; metal ion binding [GO:0046872]; small GTPase binding [GO:0031267] 0.87712 0.00011312 AVELVNTWTER 0 0 0 0 0 0 9.36385 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8744 P98175 RBM10_HUMAN RNA-binding protein 10 (G patch domain-containing protein 9) (RNA-binding motif protein 10) (RNA-binding protein S1-1) (S1-1) RBM10 DXS8237E GPATC9 GPATCH9 KIAA0122 Homo sapiens (Human) "3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; vascular associated smooth muscle cell apoptotic process [GO:1905288]; vascular associated smooth muscle cell proliferation [GO:1990874]" nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; RNA binding [GO:0003723] 0.96304 -2.1916 AAERREK 0 0 0 0 0 0 0 9.01299 9.85045 0 0 0 0 0 8.91094 0 0 8.81051 0 0 0 0 9.26296 0 0 0 0 P98182 ZN200_HUMAN Zinc finger protein 200 ZNF200 ZNFMF Homo sapiens (Human) nucleus [GO:0005634] metal ion binding [GO:0046872] 0.88308 -0.038901 DVSSSLQNR 0 0 0 0 0 0 0 0 0 0 0 12.4945 0 0 0 0 0 0 0 0 9.01931 0 0 0 0 0 0 P98187 CP4F8_HUMAN Cytochrome P450 4F8 (EC 1.14.14.1) (CYPIVF8) CYP4F8 Homo sapiens (Human) icosanoid metabolic process [GO:0006690]; prostaglandin metabolic process [GO:0006693] endoplasmic reticulum membrane [GO:0005789] alkane 1-monooxygenase activity [GO:0018685]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497] 0.95006 -1.4044 AEDGLWLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.59889 0 0 0 0 0 0 0 0 9.57809 P98194 AT2C1_HUMAN Calcium-transporting ATPase type 2C member 1 (ATPase 2C1) (EC 7.2.2.10) (ATP-dependent Ca(2+) pump PMR1) (Ca(2+)/Mn(2+)-ATPase 2C1) (Secretory pathway Ca(2+)-transporting ATPase type 1) (SPCA1) ATP2C1 KIAA1347 PMR1L HUSSY-28 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; epidermis development [GO:0008544]; Golgi calcium ion homeostasis [GO:0032468]; Golgi calcium ion transport [GO:0032472]; intracellular calcium ion homeostasis [GO:0006874]; intracellular manganese ion homeostasis [GO:0030026]; manganese ion transport [GO:0006828]; positive regulation of Golgi to plasma membrane protein transport [GO:0042998]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; trans-Golgi network membrane organization [GO:0098629] cis-Golgi network membrane [GO:0033106]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; calcium ion binding [GO:0005509]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; P-type calcium transporter activity [GO:0005388]; P-type manganese transporter activity [GO:0140613] 0.95223 -1.4536 ARMGSAGLR 0 0 0 0 0 9.03053 0 0 0 0 9.54651 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P98196 AT11A_HUMAN Phospholipid-transporting ATPase IH (EC 7.6.2.1) (ATPase IS) (ATPase class VI type 11A) (P4-ATPase flippase complex alpha subunit ATP11A) ATP11A ATPIH ATPIS KIAA1021 Homo sapiens (Human) in utero embryonic development [GO:0001701]; phospholipid translocation [GO:0045332]; positive regulation of myotube differentiation [GO:0010831]; regulation of membrane lipid distribution [GO:0097035] early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; phospholipid-translocating ATPase complex [GO:1990531]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled intramembrane lipid transporter activity [GO:0140326]; magnesium ion binding [GO:0000287]; phosphatidylethanolamine flippase activity [GO:0090555]; phosphatidylserine flippase activity [GO:0140346]; phosphatidylserine floppase activity [GO:0090556] 0.95611 -1.5502 ALCLCHTVQVK 0 0 0 0 8.66633 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 P98198 AT8B2_HUMAN Phospholipid-transporting ATPase ID (EC 7.6.2.1) (ATPase class I type 8B member 2) (P4-ATPase flippase complex alpha subunit ATP8B2) ATP8B2 ATPID KIAA1137 Homo sapiens (Human) Golgi organization [GO:0007030]; monoatomic ion transmembrane transport [GO:0034220]; phospholipid translocation [GO:0045332] cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; nucleolus [GO:0005730]; phospholipid-translocating ATPase complex [GO:1990531]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled intramembrane lipid transporter activity [GO:0140326]; magnesium ion binding [GO:0000287]; phosphatidylcholine flippase activity [GO:0140345]; phosphatidylcholine floppase activity [GO:0090554] 0.94895 -1.3728 AQAPPSWSR 0 0 0 0 0 0 0 10.0798 0 0 8.93328 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q00013 EM55_HUMAN "55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1)" MPP1 DXS552E EMP55 Homo sapiens (Human) regulation of neutrophil chemotaxis [GO:0090022]; signal transduction [GO:0007165] cell-cell junction [GO:0005911]; centriolar satellite [GO:0034451]; cortical cytoskeleton [GO:0030863]; membrane [GO:0016020]; plasma membrane [GO:0005886]; stereocilium [GO:0032420] guanylate kinase activity [GO:0004385]; signaling receptor binding [GO:0005102] 0.1431 1.0268 AQFDYDPKK 0 0 0 0 0 0 0 0 0 0 8.50247 0 0 0 0 10.8866 0 0 0 0 0 0 0 0 0 0 0 Q00059 TFAM_HUMAN "Transcription factor A, mitochondrial (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6) (TCF-6) (Transcription factor 6-like 2)" TFAM TCF6 TCF6L2 Homo sapiens (Human) mitochondrial respiratory chain complex assembly [GO:0033108]; mitochondrial transcription [GO:0006390]; positive regulation of DNA-templated transcription [GO:0045893]; transcription initiation at mitochondrial promoter [GO:0006391] cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] chromatin binding [GO:0003682]; heat shock protein binding [GO:0031072]; mitochondrial promoter sequence-specific DNA binding [GO:0001018]; mitochondrial transcription factor activity [GO:0034246]; RNA binding [GO:0003723]; sequence-specific DNA binding [GO:0043565]; transcription cis-regulatory region binding [GO:0000976]; transcription coactivator binding [GO:0001223] 0.96888 -3.3761 AEWQVYK 0 0 0 0 0 0 0 0 0 0 8.87596 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q00169 PIPNA_HUMAN Phosphatidylinositol transfer protein alpha isoform (PI-TP-alpha) (PtdIns transfer protein alpha) (PtdInsTP alpha) PITPNA PITPN Homo sapiens (Human) lipid metabolic process [GO:0006629]; phospholipid transport [GO:0015914]; visual perception [GO:0007601] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634] fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]; phosphatidylcholine binding [GO:0031210]; phosphatidylcholine transfer activity [GO:0120019]; phosphatidylcholine transporter activity [GO:0008525]; phosphatidylglycerol binding [GO:1901611]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol transfer activity [GO:0008526]; stearic acid binding [GO:0070540] 0.91759 -0.85648 DYKAEEDPAK 0 11.4522 0 0 11.6038 0 0 0 0 0 0 0 0 0 11.0397 0 0 0 0 0 0 0 0 0 0 0 0 Q00325 S25A3_HUMAN "Solute carrier family 25 member 3 (Phosphate carrier protein, mitochondrial) (Phosphate transport protein) (PTP)" SLC25A3 PHC OK/SW-cl.48 Homo sapiens (Human) mitochondrial phosphate ion transmembrane transport [GO:1990547]; phosphate ion transmembrane transport [GO:0035435] extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886] inorganic phosphate transmembrane transporter activity [GO:0005315]; phosphate:proton symporter activity [GO:0015317]; protein-containing complex binding [GO:0044877] 0 11.949 CRMQVDPQK 10.9389 10.3914 10.3856 0 0 0 10.5435 10.7605 10.7756 10.78 10.3914 10.6071 0 0 0 10.2251 10.3907 10.2911 11.4677 11.1407 9.25694 10.319 0 11.4026 12.7909 12.7817 12.6235 Q00341 VIGLN_HUMAN Vigilin (High density lipoprotein-binding protein) (HDL-binding protein) HDLBP HBP VGL Homo sapiens (Human) cholesterol metabolic process [GO:0008203]; lipid transport [GO:0006869] cytoplasm [GO:0005737]; cytosol [GO:0005829]; high-density lipoprotein particle [GO:0034364]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; polysome [GO:0005844] cadherin binding [GO:0045296]; lipid binding [GO:0008289]; mRNA binding [GO:0003729]; RNA binding [GO:0003723] 0.96265 -2.6671 AVERLEVEK 0 0 11.5091 0 0 0 0 0 0 12.3548 0 0 0 10.524 10.6256 0 10.4572 0 0 0 0 0 0 0 0 9.88142 0 Q00526 CDK3_HUMAN Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3) CDK3 CDKN3 Homo sapiens (Human) cell division [GO:0051301]; cell population proliferation [GO:0008283]; DNA damage response [GO:0006974]; G0 to G1 transition [GO:0045023]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of Notch signaling pathway [GO:0045746]; protein phosphorylation [GO:0006468]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene expression [GO:0010468]; response to organic substance [GO:0010033]; signal transduction [GO:0007165] cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; nucleus [GO:0005634] ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein serine kinase activity [GO:0106310] 0.88457 -0.19702 ELKHPNIVR 0 10.2596 0 0 0 0 0 0 0 11.0496 10.739 10.9661 0 0 0 0 0 10.8773 0 0 0 0 0 0 0 0 0 Q00537 CDK17_HUMAN Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) (PCTAIRE-motif protein kinase 2) (Serine/threonine-protein kinase PCTAIRE-2) CDK17 PCTAIRE2 PCTK2 Homo sapiens (Human) protein phosphorylation [GO:0006468]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083] cytoplasm [GO:0005737]; nucleus [GO:0005634] ATP binding [GO:0005524]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310] 0.88822 -0.43597 GLAYCHRRK 0 0 0 0 0 0 0 0 0 0 0 9.48692 0 0 0 0 0 0 0 0 0 0 0 0 9.39504 0 0 Q00597 FANCC_HUMAN Fanconi anemia group C protein (Protein FACC) FANCC FAC FACC Homo sapiens (Human) brain morphogenesis [GO:0048854]; cellular response to oxidative stress [GO:0034599]; DNA repair [GO:0006281]; germ cell development [GO:0007281]; interstrand cross-link repair [GO:0036297]; myeloid cell homeostasis [GO:0002262]; neuronal stem cell population maintenance [GO:0097150]; nucleotide-excision repair [GO:0006289]; protein monoubiquitination [GO:0006513]; protein-containing complex assembly [GO:0065003]; removal of superoxide radicals [GO:0019430] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Fanconi anaemia nuclear complex [GO:0043240]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.96264 -2.0837 ILIWCLCCLINK 0 0 0 0 0 0 0 0 0 0 0 11.2567 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0505 0 Q00610 CLH1_HUMAN Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17) CLTC CLH17 CLTCL2 KIAA0034 Homo sapiens (Human) "amyloid-beta clearance by transcytosis [GO:0150093]; autophagy [GO:0006914]; cell division [GO:0051301]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; mitotic cell cycle [GO:0000278]; negative regulation of hyaluronan biosynthetic process [GO:1900126]; negative regulation of protein localization to plasma membrane [GO:1903077]; osteoblast differentiation [GO:0001649]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of mitotic spindle organization [GO:0060236]; retrograde transport, endosome to Golgi [GO:0042147]; transferrin transport [GO:0033572]" clathrin coat [GO:0030118]; clathrin coat of coated pit [GO:0030132]; clathrin coat of trans-Golgi network vesicle [GO:0030130]; clathrin complex [GO:0071439]; clathrin-coated endocytic vesicle [GO:0045334]; clathrin-coated endocytic vesicle membrane [GO:0030669]; clathrin-coated vesicle [GO:0030136]; cytosol [GO:0005829]; endolysosome membrane [GO:0036020]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular vesicle [GO:1903561]; focal adhesion [GO:0005925]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane [GO:0016020]; mitotic spindle [GO:0072686]; mitotic spindle microtubule [GO:1990498]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; spindle [GO:0005819]; trans-Golgi network membrane [GO:0032588] clathrin light chain binding [GO:0032051]; disordered domain specific binding [GO:0097718]; double-stranded RNA binding [GO:0003725]; low-density lipoprotein particle receptor binding [GO:0050750]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; ubiquitin-specific protease binding [GO:1990381] 0 17.924 AQILPIR 8.54894 9.75817 9.38146 0 8.82369 0 10.6018 10.0058 0 11.0404 11.9974 10.8253 0 0 12.5671 9.47905 11.2052 9.73927 0 10.4818 9.71929 11.1717 0 0 12.3013 11.2606 0 Q00613 HSF1_HUMAN Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1) HSF1 HSTF1 Homo sapiens (Human) cellular response to angiotensin [GO:1904385]; cellular response to cadmium ion [GO:0071276]; cellular response to copper ion [GO:0071280]; cellular response to diamide [GO:0072738]; cellular response to estradiol stimulus [GO:0071392]; cellular response to gamma radiation [GO:0071480]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to L-glutamine [GO:1904845]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nitroglycerin [GO:1904843]; cellular response to potassium ion [GO:0035865]; cellular response to sodium arsenite [GO:1903936]; cellular response to unfolded protein [GO:0034620]; cellular response to xenobiotic stimulus [GO:0071466]; defense response [GO:0006952]; DNA repair [GO:0006281]; MAPK cascade [GO:0000165]; mRNA processing [GO:0006397]; mRNA transcription [GO:0009299]; mRNA transport [GO:0051028]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of double-strand break repair via nonhomologous end joining [GO:2001033]; negative regulation of gene expression [GO:0010629]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of neuron death [GO:1901215]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of gene expression [GO:0010628]; positive regulation of inclusion body assembly [GO:0090261]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of mRNA polyadenylation [GO:1900365]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein-containing complex assembly [GO:0065003]; regulation of cellular response to heat [GO:1900034]; regulation of transcription by RNA polymerase II [GO:0006357]; response to activity [GO:0014823]; response to hypobaric hypoxia [GO:1990910]; response to nutrient [GO:0007584]; response to psychosocial stress [GO:1990911]; response to testosterone [GO:0033574] centrosome [GO:0005813]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; heterochromatin [GO:0000792]; kinetochore [GO:0000776]; mitotic spindle pole [GO:0097431]; nuclear stress granule [GO:0097165]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; PML body [GO:0016605]; protein folding chaperone complex [GO:0101031]; ribonucleoprotein complex [GO:1990904] "chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; general transcription initiation factor binding [GO:0140296]; heat shock protein binding [GO:0031072]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding [GO:0001162]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; sequence-specific single stranded DNA binding [GO:0098847]; STAT family protein binding [GO:0097677]; transcription cis-regulatory region binding [GO:0000976]; translation elongation factor binding [GO:0061770]" 0.84753 0.1281 GHTDTEGRPPSPPPTSTPEK 0 0 0 0 0 0 0 0 0 0 0 8.75809 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q00688 FKBP3_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP3 (PPIase FKBP3) (EC 5.2.1.8) (25 kDa FK506-binding protein) (25 kDa FKBP) (FKBP-25) (FK506-binding protein 3) (FKBP-3) (Immunophilin FKBP25) (Rapamycin-selective 25 kDa immunophilin) (Rotamase) FKBP3 FKBP25 Homo sapiens (Human) nucleus [GO:0005634] FK506 binding [GO:0005528]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; signaling receptor activity [GO:0038023] 0.73767 0.32671 AWTVEQLR 0 8.529 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q00722 PLCB2_HUMAN "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-2) (Phospholipase C-beta-2) (PLC-beta-2)" PLCB2 Homo sapiens (Human) activation of phospholipase C activity [GO:0007202]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; G protein-coupled receptor signaling pathway [GO:0007186]; lipid catabolic process [GO:0016042]; phosphatidylinositol metabolic process [GO:0046488]; phosphatidylinositol-mediated signaling [GO:0048015]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; phospholipid metabolic process [GO:0006644]; release of sequestered calcium ion into cytosol [GO:0051209] cytosol [GO:0005829]; G-protein beta/gamma-subunit complex [GO:0031680]; Golgi apparatus [GO:0005794]; neuronal dense core vesicle [GO:0098992]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; G-protein beta/gamma-subunit complex binding [GO:0031683]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipase C activity [GO:0004629]; phospholipid binding [GO:0005543] 0.96939 -3.1997 LEEKQAACLEQIREMEK 0 0 0 0 0 0 0 0 0 0 0 10.5593 0 0 9.13756 0 0 0 10.6245 0 9.88292 0 0 0 0 0 0 Q00765 REEP5_HUMAN Receptor expression-enhancing protein 5 (Polyposis locus protein 1) (Protein TB2) REEP5 C5orf18 DP1 TB2 Homo sapiens (Human) endoplasmic reticulum membrane organization [GO:0090158]; endoplasmic reticulum organization [GO:0007029]; regulation of intracellular transport [GO:0032386] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum tubular network [GO:0071782]; sarcoplasmic reticulum membrane [GO:0033017] 0.95309 -1.4884 ATVNLLGEEK 0 0 0 0 0 0 0 0 0 0 0 0 0 12.0034 11.9285 0 0 0 0 0 0 10.5097 0 0 11.1584 11.4018 11.251 Q00796 DHSO_HUMAN "Sorbitol dehydrogenase (SDH) (EC 1.1.1.-) ((R,R)-butanediol dehydrogenase) (EC 1.1.1.4) (L-iditol 2-dehydrogenase) (EC 1.1.1.14) (Polyol dehydrogenase) (Ribitol dehydrogenase) (RDH) (EC 1.1.1.56) (Xylitol dehydrogenase) (XDH) (EC 1.1.1.9)" SORD Homo sapiens (Human) flagellated sperm motility [GO:0030317]; fructose biosynthetic process [GO:0046370]; glucose metabolic process [GO:0006006]; glucuronate catabolic process to xylulose 5-phosphate [GO:0019640]; L-xylitol catabolic process [GO:0051160]; L-xylitol metabolic process [GO:0051164]; response to cadmium ion [GO:0046686]; response to copper ion [GO:0046688]; response to hormone [GO:0009725]; response to nutrient levels [GO:0031667]; response to osmotic stress [GO:0006970]; response to xenobiotic stimulus [GO:0009410]; sorbitol catabolic process [GO:0006062] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrial membrane [GO:0031966]; motile cilium [GO:0031514] "(R,R)-butanediol dehydrogenase activity [GO:0000721]; carbohydrate binding [GO:0030246]; D-sorbitol dehydrogenase (acceptor) activity [GO:0047833]; D-xylulose reductase activity [GO:0046526]; identical protein binding [GO:0042802]; L-iditol 2-dehydrogenase activity [GO:0003939]; NAD binding [GO:0051287]; ribitol 2-dehydrogenase activity [GO:0050255]; zinc ion binding [GO:0008270]" 0.8307 0.20246 AMGAAQVVVTDLSATRLSK 0 0 0 0 0 0 0 0 9.17779 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q00839 HNRPU_HUMAN Heterogeneous nuclear ribonucleoprotein U (hnRNP U) (GRIP120) (Nuclear p120 ribonucleoprotein) (Scaffold-attachment factor A) (SAF-A) (p120) (pp120) HNRNPU C1orf199 HNRPU SAFA U21.1 Homo sapiens (Human) "adaptive thermogenesis [GO:1990845]; cardiac muscle cell development [GO:0055013]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to leukemia inhibitory factor [GO:1990830]; chromatin organization [GO:0006325]; circadian regulation of gene expression [GO:0032922]; CRD-mediated mRNA stabilization [GO:0070934]; dendritic transport of messenger ribonucleoprotein complex [GO:0098963]; dosage compensation by inactivation of X chromosome [GO:0009048]; maintenance of protein location in nucleus [GO:0051457]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of kinase activity [GO:0033673]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; osteoblast differentiation [GO:0001649]; positive regulation of attachment of mitotic spindle microtubules to kinetochore [GO:1902425]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity [GO:2000373]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to spindle microtubule [GO:1902889]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of chromatin organization [GO:1902275]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic spindle assembly [GO:1901673]; RNA localization to chromatin [GO:1990280]; RNA processing [GO:0006396]" catalytic step 2 spliceosome [GO:0071013]; cell surface [GO:0009986]; centrosome [GO:0005813]; CRD-mediated mRNA stability complex [GO:0070937]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; inactive sex chromosome [GO:0098577]; kinetochore [GO:0000776]; membrane [GO:0016020]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; mitotic spindle microtubule [GO:1990498]; mitotic spindle midzone [GO:1990023]; nuclear chromosome [GO:0000228]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; spindle pole [GO:0000922]; telomerase holoenzyme complex [GO:0005697] actin binding [GO:0003779]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; lncRNA binding [GO:0106222]; mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(C) RNA binding [GO:0017130]; poly(G) binding [GO:0034046]; pre-mRNA binding [GO:0036002]; promoter-specific chromatin binding [GO:1990841]; protein-containing complex binding [GO:0044877]; ribonucleoprotein complex binding [GO:0043021]; RNA binding [GO:0003723]; RNA polymerase II C-terminal domain binding [GO:0099122]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II complex binding [GO:0000993]; sequence-specific double-stranded DNA binding [GO:1990837]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; snRNA binding [GO:0017069]; telomerase RNA binding [GO:0070034]; TFIIH-class transcription factor complex binding [GO:0001097]; transcription corepressor activity [GO:0003714] 0 34.871 FIEIAAR 0 0 0 0 0 0 10.1573 9.28519 9.2681 8.73579 0 8.84166 11.2154 10.317 10.56 12.2296 11.5322 10.1379 11.7746 11.1258 11.4163 9.54191 11.4437 11.3646 11.3208 10.7566 12.4406 Q00872 MYPC1_HUMAN "Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform)" MYBPC1 MYBPCS Homo sapiens (Human) cell adhesion [GO:0007155] cytosol [GO:0005829]; myofibril [GO:0030016]; myosin filament [GO:0032982] actin binding [GO:0003779]; myosin binding [GO:0017022]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432] 0.96394 -2.4104 EKEAGTTPAK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.31931 0 0 0 0 0 0 0 0 9.11291 9.65625 0 0 0 Q00888 PSG4_HUMAN Pregnancy-specific beta-1-glycoprotein 4 (PS-beta-G-4) (PSBG-4) (Pregnancy-specific glycoprotein 4) (Pregnancy-specific beta-1-glycoprotein 9) (PS-beta-G-9) (PSBG-9) (Pregnancy-specific glycoprotein 9) PSG4 CGM4 PSG9 Homo sapiens (Human) female pregnancy [GO:0007565]; regulation of immune system process [GO:0002682]; signal transduction [GO:0007165] cell surface [GO:0009986]; extracellular region [GO:0005576]; plasma membrane [GO:0005886] protein tyrosine kinase binding [GO:1990782] 0.89003 -0.45899 DVLTFTCEPK 0 0 0 0 0 0 0 0 0 0 9.34018 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4407 0 10.4008 Q008S8 ECT2L_HUMAN Epithelial cell-transforming sequence 2 oncogene-like (Lung-specific F-box and DH domain-containing protein) (Putative guanine nucleotide exchange factor LFDH) ECT2L C6orf91 LFDH Homo sapiens (Human) guanyl-nucleotide exchange factor activity [GO:0005085] 0.9468 -1.3489 FLTEQDCLWMPKCVK 0 0 0 0 0 0 9.48541 0 0 0 0 0 0 0 8.71603 0 0 0 0 0 0 10.0661 0 0 0 0 0 Q00973 B4GN1_HUMAN "Beta-1,4 N-acetylgalactosaminyltransferase 1 (EC 2.4.1.92) ((N-acetylneuraminyl)-galactosylglucosylceramide) (GM2/GD2 synthase) (GalNAc-T)" B4GALNT1 GALGT SIAT2 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; determination of adult lifespan [GO:0008340]; ganglioside biosynthetic process [GO:0001574]; glycosphingolipid metabolic process [GO:0006687]; limb development [GO:0060173]; lipid glycosylation [GO:0030259]; lipid storage [GO:0019915]; motor behavior [GO:0061744]; nerve development [GO:0021675]; spermatogenesis [GO:0007283]; vacuole organization [GO:0007033] Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020] (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity [GO:0003947] 0.88337 -0.0703 EVGFDPR 0 0 0 10.5465 0 10.5063 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.90346 0 0 0 0 0 Q00975 CAC1B_HUMAN "Voltage-dependent N-type calcium channel subunit alpha-1B (Brain calcium channel III) (BIII) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Voltage-gated calcium channel subunit alpha Cav2.2)" CACNA1B CACH5 CACNL1A5 Homo sapiens (Human) calcium ion import across plasma membrane [GO:0098703]; chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; regulation of monoatomic ion transmembrane transport [GO:0034765]; response to amyloid-beta [GO:1904645] neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; synapse [GO:0045202]; voltage-gated calcium channel complex [GO:0005891] amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; high voltage-gated calcium channel activity [GO:0008331]; voltage-gated calcium channel activity [GO:0005245] 0.95953 -1.9124 FGDELGGRYGGPGGGERAR 11.3136 11.1403 0 12.7934 12.8525 12.5009 11.367 0 11.333 0 0 0 0 8.88243 9.29655 9.23903 0 0 0 0 0 0 0 0 0 0 0 Q00987 MDM2_HUMAN E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27) (Double minute 2 protein) (Hdm2) (Oncoprotein Mdm2) (RING-type E3 ubiquitin transferase Mdm2) (p53-binding protein Mdm2) MDM2 Homo sapiens (Human) "amyloid fibril formation [GO:1990000]; apoptotic process [GO:0006915]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac septum morphogenesis [GO:0060411]; cellular response to actinomycin D [GO:0072717]; cellular response to gamma radiation [GO:0071480]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; establishment of protein localization [GO:0045184]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein destabilization [GO:0031648]; protein localization to nucleus [GO:0034504]; protein polyubiquitination [GO:0000209]; protein sumoylation [GO:0016925]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of cell cycle [GO:0051726]; regulation of gene expression [GO:0010468]; regulation of heart rate [GO:0002027]; regulation of protein catabolic process [GO:0042176]; response to antibiotic [GO:0046677]; transcription factor catabolic process [GO:0036369]; traversing start control point of mitotic cell cycle [GO:0007089]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular septum development [GO:0003281]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; transcription repressor complex [GO:0017053] 5S rRNA binding [GO:0008097]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; ligase activity [GO:0016874]; NEDD8 ligase activity [GO:0061663]; p53 binding [GO:0002039]; protein domain specific binding [GO:0019904]; ribonucleoprotein complex binding [GO:0043021]; SUMO transferase activity [GO:0019789]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.55947 0.54072 ENWLPEDKGKDK 0 0 0 0 0 0 0 0 0 0 0 0 8.93154 0 0 0 0 0 0 0 0 0 9.25302 0 0 0 0 Q01082 SPTB2_HUMAN "Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1)" SPTBN1 SPTB2 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament capping [GO:0051693]; central nervous system development [GO:0007417]; central nervous system formation [GO:0021556]; common-partner SMAD protein phosphorylation [GO:0007182]; Golgi to plasma membrane protein transport [GO:0043001]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; plasma membrane organization [GO:0007009]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of SMAD protein signal transduction [GO:0060390] axolemma [GO:0030673]; cell junction [GO:0030054]; cell projection [GO:0042995]; cortical actin cytoskeleton [GO:0030864]; cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; M band [GO:0031430]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; spectrin [GO:0008091]; spectrin-associated cytoskeleton [GO:0014731] actin binding [GO:0003779]; actin filament binding [GO:0051015]; ankyrin binding [GO:0030506]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; GTPase binding [GO:0051020]; phospholipid binding [GO:0005543]; RNA binding [GO:0003723]; structural constituent of cytoskeleton [GO:0005200] 0.21713 0.88583 DALLLWCQMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.24698 0 9.85259 9.55855 0 Q01085 TIAR_HUMAN Nucleolysin TIAR (TIA-1-related protein) TIAL1 Homo sapiens (Human) apoptotic process [GO:0006915]; defense response [GO:0006952]; germ cell development [GO:0007281]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of hippo signaling [GO:0035332]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; positive regulation of stem cell proliferation [GO:2000648]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell division [GO:0017145]; stem cell proliferation [GO:0072089] cytolytic granule [GO:0044194]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; protein-RNA adaptor activity [GO:0140517]; RNA binding [GO:0003723] 0.61325 0.42609 FEDVVNQSSPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3382 0 0 0 0 0 0 11.1881 0 0 Q01105 SET_HUMAN Protein SET (HLA-DR-associated protein II) (Inhibitor of granzyme A-activated DNase) (IGAAD) (PHAPII) (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template-activating factor I) (TAF-I) SET Homo sapiens (Human) DNA replication [GO:0006260]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of histone acetylation [GO:0035067]; negative regulation of neuron apoptotic process [GO:0043524]; nucleosome assembly [GO:0006334]; nucleosome disassembly [GO:0006337] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; histone binding [GO:0042393]; protein phosphatase inhibitor activity [GO:0004864]; protein phosphatase regulator activity [GO:0019888] 0 6.3273 DLTKRSSQTQNK 9.85599 10.1787 9.59074 0 0 0 9.85022 0 0 10.7017 11.5568 11.0485 0 9.59104 11.0386 11.2349 10.433 10.9538 9.27125 0 0 9.35229 0 0 0 0 0 Q01118 SCN7A_HUMAN Sodium channel protein type 7 subunit alpha (Putative voltage-gated sodium channel subunit alpha Nax) (Sodium channel protein cardiac and skeletal muscle subunit alpha) (Sodium channel protein type VII subunit alpha) SCN7A SCN6A Homo sapiens (Human) calcium ion import across plasma membrane [GO:0098703]; cellular homeostasis [GO:0019725]; muscle contraction [GO:0006936]; regulation of monoatomic ion transmembrane transport [GO:0034765]; response to bacterium [GO:0009617]; sodium ion homeostasis [GO:0055078]; sodium ion transport [GO:0006814] glial cell projection [GO:0097386]; voltage-gated calcium channel complex [GO:0005891]; voltage-gated sodium channel complex [GO:0001518] high voltage-gated calcium channel activity [GO:0008331]; voltage-gated sodium channel activity [GO:0005248] 0.559 0.53083 FPSSEVMNKSR 9.19407 8.64821 0 0 0 0 8.82566 0 0 0 0 0 0 0 0 8.93893 8.83652 0 0 0 0 0 0 0 0 10.0871 0 Q01130 SRSF2_HUMAN "Serine/arginine-rich splicing factor 2 (Protein PR264) (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2)" SRSF2 SFRS2 Homo sapiens (Human) "mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]" cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714] 0.36905 0.73682 VGDVYIPR 0 0 0 0 0 0 0 0 0 0 0 8.59965 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q01167 FOXK2_HUMAN Forkhead box protein K2 (G/T-mismatch specific binding protein) (nGTBP) (Interleukin enhancer-binding factor 1) FOXK2 ILF ILF1 Homo sapiens (Human) canonical glycolysis [GO:0061621]; intracellular glucose homeostasis [GO:0001678]; negative regulation of autophagy [GO:0010507]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of glucose metabolic process [GO:0010906]; regulation of transcription by RNA polymerase II [GO:0006357]; response to starvation [GO:0042594] chromatin [GO:0000785]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; magnesium ion binding [GO:0000287]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription cis-regulatory region binding [GO:0000976]" 0.55818 0.53753 RGAPPLQLPRVCTFR 0 0 12.0912 0 0 0 10.1312 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q01201 RELB_HUMAN Transcription factor RelB (I-Rel) RELB Homo sapiens (Human) antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of interferon-beta production [GO:0032688]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063] chromatin [GO:0000785]; cytosol [GO:0005829]; microtubule organizing center [GO:0005815]; NF-kappaB complex [GO:0071159]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transcription repressor complex [GO:0017053] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.91386 -0.79682 KSTNTSELR 0 0 0 0 0 0 0 0 0 0 0 0 0 8.95527 0 0 0 0 0 0 0 0 0 0 0 0 0 Q01344 IL5RA_HUMAN Interleukin-5 receptor subunit alpha (IL-5 receptor subunit alpha) (IL-5R subunit alpha) (IL-5R-alpha) (IL-5RA) (CDw125) (CD antigen CD125) IL5RA IL5R Homo sapiens (Human) cytokine-mediated signaling pathway [GO:0019221]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-5-mediated signaling pathway [GO:0038043]; positive regulation of leukocyte proliferation [GO:0070665]; regulation of interleukin-5 production [GO:0032674]; signal transduction [GO:0007165] external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interleukin-5 receptor activity [GO:0004914] 0.91662 -0.84847 DLFVTTNYEK 0 0 9.07082 9.55718 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q01415 GALK2_HUMAN N-acetylgalactosamine kinase (EC 2.7.1.157) (GalNAc kinase) (Galactokinase 2) GALK2 GK2 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; galactose metabolic process [GO:0006012] cytosol [GO:0005829] ATP binding [GO:0005524]; galactokinase activity [GO:0004335]; N-acetylgalactosamine kinase activity [GO:0033858] 0.8501 0.16569 TKPLWHNYFLCGLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.53103 0 0 0 0 0 0 Q01432 AMPD3_HUMAN AMP deaminase 3 (EC 3.5.4.6) (AMP deaminase isoform E) (Erythrocyte AMP deaminase) AMPD3 Homo sapiens (Human) AMP catabolic process [GO:0006196]; AMP metabolic process [GO:0046033]; IMP biosynthetic process [GO:0006188]; IMP salvage [GO:0032264] cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774] AMP deaminase activity [GO:0003876]; metal ion binding [GO:0046872] 0.96996 -4.3862 ELHLFLK 0 0 0 0 0 0 0 0 0 10.0721 0 0 10.6992 0 0 0 0 0 0 0 10.1778 0 9.56824 0 0 9.78409 0 Q01449 MLRA_HUMAN "Myosin regulatory light chain 2, atrial isoform (MLC-2a) (MLC2a) (Myosin light chain 2a) (Myosin regulatory light chain 7)" MYL7 MYL2A MYLC2A Homo sapiens (Human) cardiac muscle tissue development [GO:0048738]; heart contraction [GO:0060047] A band [GO:0031672]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; myofibril [GO:0030016]; myosin complex [GO:0016459] calcium ion binding [GO:0005509] 0.95259 -1.4921 GVVNKDEFK 0 0 0 0 0 0 0 0 0 0 9.3059 0 0 0 0 0 9.99859 0 0 0 0 0 0 0 0 0 0 Q01459 DIAC_HUMAN Di-N-acetylchitobiase (EC 3.2.1.-) CTBS CTB Homo sapiens (Human) chitin catabolic process [GO:0006032]; oligosaccharide catabolic process [GO:0009313] extracellular space [GO:0005615]; lysosome [GO:0005764] chitin binding [GO:0008061]; chitinase activity [GO:0004568] 0.88267 -0.30027 DQRAPYYNYK 0 0 0 0 0 0 0 0 0 9.61736 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q01469 FABP5_HUMAN "Fatty acid-binding protein 5 (Epidermal-type fatty acid-binding protein) (E-FABP) (Fatty acid-binding protein, epidermal) (Psoriasis-associated fatty acid-binding protein homolog) (PA-FABP)" FABP5 Homo sapiens (Human) epidermis development [GO:0008544]; fatty acid transport [GO:0015908]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; lipid transport across blood-brain barrier [GO:1990379]; long-chain fatty acid transport [GO:0015909]; negative regulation of glucose transmembrane transport [GO:0010829]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360]; regulation of prostaglandin biosynthetic process [GO:0031392]; regulation of retrograde trans-synaptic signaling by endocanabinoid [GO:0099178]; regulation of sensory perception of pain [GO:0051930] azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; secretory granule membrane [GO:0030667]; synapse [GO:0045202] fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; long-chain fatty acid transporter activity [GO:0005324]; retinoic acid binding [GO:0001972] 0 13.471 ATVQQLEGR 0 0 8.62077 0 0 0 9.17764 0 0 11.3142 11.5467 11.1093 0 0 0 11.2561 11.428 0 0 0 0 0 0 9.98242 0 0 0 Q01484 ANK2_HUMAN Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin) ANK2 ANKB Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; endocytosis [GO:0006897]; intracellular calcium ion homeostasis [GO:0006874]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] A band [GO:0031672]; apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; intercalated disc [GO:0014704]; lysosome [GO:0005764]; M band [GO:0031430]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; recycling endosome [GO:0055037]; sarcolemma [GO:0042383]; T-tubule [GO:0030315]; Z disc [GO:0030018] ATPase binding [GO:0051117]; cytoskeletal anchor activity [GO:0008093]; enzyme binding [GO:0019899]; phosphorylation-dependent protein binding [GO:0140031]; protein kinase binding [GO:0019901]; protein-macromolecule adaptor activity [GO:0030674]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]; transmembrane transporter binding [GO:0044325] 0.96909 -6.5485 CTAPTRVTCRLVK 10.4839 0 0 0 0 0 10.1209 10.7459 10.037 0 10.8422 12.0732 0 9.33684 0 10.1018 9.67694 0 10.1911 0 0 0 0 0 0 0 0 Q01518 CAP1_HUMAN Adenylyl cyclase-associated protein 1 (CAP 1) CAP1 CAP Homo sapiens (Human) actin filament organization [GO:0007015]; activation of adenylate cyclase activity [GO:0007190]; ameboidal-type cell migration [GO:0001667]; cAMP-mediated signaling [GO:0019933]; cell morphogenesis [GO:0000902]; establishment or maintenance of cell polarity [GO:0007163]; receptor-mediated endocytosis [GO:0006898]; signal transduction [GO:0007165] azurophil granule lumen [GO:0035578]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886] actin binding [GO:0003779]; adenylate cyclase binding [GO:0008179] 0.020642 1.623 ADMQNLVER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.70929 0 9.36186 Q01538 MYT1_HUMAN Myelin transcription factor 1 (MyT1) (Myelin transcription factor I) (MyTI) (PLPB1) (Proteolipid protein-binding protein) MYT1 KIAA0835 KIAA1050 MTF1 MYTI PLPB1 Homo sapiens (Human) cell differentiation [GO:0030154]; nervous system development [GO:0007399]; regulation of DNA-templated transcription [GO:0006355] chromatin [GO:0000785]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; zinc ion binding [GO:0008270]" 0.89276 -0.5137 DDKEDPELMK 0 0 0 0 0 9.48688 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q01581 HMCS1_HUMAN "Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMG-CoA synthase) (EC 2.3.3.10) (3-hydroxy-3-methylglutaryl coenzyme A synthase)" HMGCS1 HMGCS Homo sapiens (Human) "acetyl-CoA metabolic process [GO:0006084]; cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process, mevalonate pathway [GO:0010142]; lipid metabolic process [GO:0006629]" cytoplasm [GO:0005737]; cytosol [GO:0005829] hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; protein homodimerization activity [GO:0042803] 0.73297 0.33041 NNLSYDCIGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.08775 0 9.12272 0 0 10.762 0 Q01638 ILRL1_HUMAN Interleukin-1 receptor-like 1 (EC 3.2.2.6) (Protein ST2) IL1RL1 DER4 ST2 T1 Homo sapiens (Human) immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-33-mediated signaling pathway [GO:0038172]; macrophage differentiation [GO:0030225]; negative regulation of T-helper 1 type immune response [GO:0002826]; negative regulation of type II interferon production [GO:0032689]; positive regulation of chemokine production [GO:0032722]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-5 production [GO:0032754]; positive regulation of macrophage activation [GO:0043032]; signal transduction [GO:0007165] cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886] "cytokine receptor activity [GO:0004896]; interleukin-1 receptor activity [GO:0004908]; interleukin-33 binding [GO:0002113]; interleukin-33 receptor activity [GO:0002114]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]" 0.41978 0.6776 KQSDCNVPDYLMYSTVSGSEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.62903 0 0 0 0 0 0 0 0 0 9.35546 0 Q01664 TFAP4_HUMAN Transcription factor AP-4 (Activating enhancer-binding protein 4) (Class C basic helix-loop-helix protein 41) (bHLHc41) TFAP4 BHLHC41 Homo sapiens (Human) "cellular response to dexamethasone stimulus [GO:0071549]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of DNA-templated transcription [GO:0045893]; protein-containing complex assembly [GO:0065003]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of transcription by RNA polymerase II [GO:0006357]" chromatin [GO:0000785]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription repressor complex [GO:0017053] "DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; E-box binding [GO:0070888]; histone deacetylase binding [GO:0042826]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]" 0.82516 0.21471 EEPSGDGELP 0 0 0 9.48087 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q01668 CAC1D_HUMAN "Voltage-dependent L-type calcium channel subunit alpha-1D (Calcium channel, L type, alpha-1 polypeptide, isoform 2) (Voltage-gated calcium channel subunit alpha Cav1.3)" CACNA1D CACH3 CACN4 CACNL1A2 CCHL1A2 Homo sapiens (Human) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; calcium ion import [GO:0070509]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cardiac muscle cell action potential involved in contraction [GO:0086002]; membrane depolarization during cardiac muscle cell action potential [GO:0086012]; membrane depolarization during SA node cell action potential [GO:0086046]; positive regulation of adenylate cyclase activity [GO:0045762]; positive regulation of calcium ion transport [GO:0051928]; regulation of atrial cardiac muscle cell membrane repolarization [GO:0060372]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of potassium ion transmembrane transporter activity [GO:1901016]; sensory perception of sound [GO:0007605] L-type voltage-gated calcium channel complex [GO:1990454]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018] alpha-actinin binding [GO:0051393]; ankyrin binding [GO:0030506]; calcium channel activity [GO:0005262]; metal ion binding [GO:0046872]; voltage-gated calcium channel activity [GO:0005245]; voltage-gated calcium channel activity involved in cardiac muscle cell action potential [GO:0086007]; voltage-gated calcium channel activity involved SA node cell action potential [GO:0086059] 0.96184 -2.0478 GRIKHLDVVTLLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.75113 Q01780 EXOSX_HUMAN Exosome component 10 (EC 3.1.13.-) (Autoantigen PM/Scl 2) (P100 polymyositis-scleroderma overlap syndrome-associated autoantigen) (Polymyositis/scleroderma autoantigen 100 kDa) (PM/Scl-100) (Polymyositis/scleroderma autoantigen 2) EXOSC10 PMSCL PMSCL2 RRP6 Homo sapiens (Human) "CUT catabolic process [GO:0071034]; dosage compensation by inactivation of X chromosome [GO:0009048]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; histone mRNA catabolic process [GO:0071044]; maturation of 5.8S rRNA [GO:0000460]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent antisense transcript catabolic process [GO:0071040]; nuclear polyadenylation-dependent CUT catabolic process [GO:0071039]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent snoRNA catabolic process [GO:0071036]; nuclear polyadenylation-dependent snRNA catabolic process [GO:0071037]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; regulation of telomerase RNA localization to Cajal body [GO:1904872]; ribosomal small subunit biogenesis [GO:0042274]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; rRNA processing [GO:0006364]" cytoplasm [GO:0005737]; cytoplasmic exosome (RNase complex) [GO:0000177]; cytosol [GO:0005829]; euchromatin [GO:0000791]; exosome (RNase complex) [GO:0000178]; membrane [GO:0016020]; nuclear exosome (RNase complex) [GO:0000176]; nucleolar exosome (RNase complex) [GO:0101019]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; small-subunit processome [GO:0032040] 3'-5'-RNA exonuclease activity [GO:0000175]; nucleotide binding [GO:0000166]; RNA binding [GO:0003723]; RNA exonuclease activity [GO:0004532]; single-stranded RNA binding [GO:0003727]; telomerase RNA binding [GO:0070034] 0.93387 -1.2821 ATSDPRTTEQK 0 0 0 0 0 0 0 0 0 0 0 0 9.19992 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q01813 PFKAP_HUMAN "ATP-dependent 6-phosphofructokinase, platelet type (ATP-PFK) (PFK-P) (EC 2.7.1.11) (6-phosphofructokinase type C) (Phosphofructo-1-kinase isozyme C) (PFK-C) (Phosphohexokinase)" PFKP PFKF Homo sapiens (Human) "canonical glycolysis [GO:0061621]; cellular response to leukemia inhibitory factor [GO:1990830]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose 6-phosphate metabolic process [GO:0006002]" 6-phosphofructokinase complex [GO:0005945]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634] 6-phosphofructokinase activity [GO:0003872]; AMP binding [GO:0016208]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; fructose-6-phosphate binding [GO:0070095]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]; protein-containing complex binding [GO:0044877] 0.88288 -0.039614 AACNLLQR 10.4102 0 10.4597 0 0 0 10.8888 0 10.8771 10.5688 10.5274 10.7973 0 9.51704 0 0 10.355 9.99421 0 0 0 0 0 0 9.43627 11.2165 10.6654 Q01814 AT2B2_HUMAN Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2) ATP2B2 PMCA2 Homo sapiens (Human) brain development [GO:0007420]; calcium ion transport [GO:0006816]; monoatomic ion transmembrane transport [GO:0034220]; neural retina development [GO:0003407]; neuron differentiation [GO:0030182]; regulation of cardiac conduction [GO:1903779]; regulation of cytosolic calcium ion concentration [GO:0051480]; sensory perception of sound [GO:0007605] apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cytoplasm [GO:0005737]; dendritic spine membrane [GO:0032591]; extracellular exosome [GO:0070062]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; membrane raft [GO:0045121]; neuronal cell body membrane [GO:0032809]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; presynaptic active zone membrane [GO:0048787] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; glutamate receptor binding [GO:0035254]; metal ion binding [GO:0046872]; P-type calcium transporter activity [GO:0005388]; P-type calcium transporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration [GO:1905059]; PDZ domain binding [GO:0030165] 0.92295 -1.0763 GLNRIQTQIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.123 0 0 0 9.83091 9.60454 9.58731 Q01844 EWS_HUMAN RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein) EWSR1 EWS Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] Cajal body [GO:0015030]; cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; transcription coregulator activity [GO:0003712] 0.95972 -1.7909 GGPGGMR 0 0 0 0 0 0 0 0 0 0 8.97943 0 0 0 0 0 0 0 9.42503 10.0153 0 0 0 0 0 0 0 Q01850 CDR2_HUMAN Cerebellar degeneration-related protein 2 (Major Yo paraneoplastic antigen) (Paraneoplastic cerebellar degeneration-associated antigen) CDR2 PCD17 Homo sapiens (Human) cytoplasm [GO:0005737] 0.87051 0.028344 TKQEIDEQR 0 0 0 0 0 0 8.74836 0 0 0 0 0 0 0 0 0 10.9096 0 0 0 0 0 0 0 0 0 0 Q01892 SPIB_HUMAN Transcription factor Spi-B SPIB Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.91993 -0.9078 ELLARRWGQQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.0011 0 0 0 0 10.0151 0 0 Q01954 BNC1_HUMAN Zinc finger protein basonuclin-1 BNC1 BNC Homo sapiens (Human) cell differentiation [GO:0030154]; epidermis development [GO:0008544]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of oocyte maturation [GO:1900195]; positive regulation of transcription by RNA polymerase I [GO:0045943]; regulation of transcription by RNA polymerase I [GO:0006356]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA-binding transcription activator activity [GO:0001216]; metal ion binding [GO:0046872]; rDNA binding [GO:0000182] 0.96762 -2.8536 IHHKNMHVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0284 0 0 9.82112 0 0 0 0 0 0 0 0 0 Q01955 CO4A3_HUMAN Collagen alpha-3(IV) chain (Goodpasture antigen) [Cleaved into: Tumstatin] COL4A3 Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; blood circulation [GO:0008015]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; endothelial cell apoptotic process [GO:0072577]; extracellular matrix organization [GO:0030198]; glomerular basement membrane development [GO:0032836]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; response to glucose [GO:0009749]; sensory perception of sound [GO:0007605] basement membrane [GO:0005604]; collagen type IV trimer [GO:0005587]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231] extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020]; integrin binding [GO:0005178]; metalloendopeptidase inhibitor activity [GO:0008191]; structural molecule activity [GO:0005198] 0.8847 -0.28397 APPGPRGNPGAQGAK 0 0 0 0 0 0 0 0 0 0 0 11.9866 0 0 0 0 0 11.6288 0 0 0 0 0 0 0 0 0 Q01968 OCRL_HUMAN "Inositol polyphosphate 5-phosphatase OCRL (EC 3.1.3.36) (EC 3.1.3.56) (Inositol polyphosphate 5-phosphatase OCRL-1) (OCRL-1) (Lowe oculocerebrorenal syndrome protein) (Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase) (EC 3.1.3.86)" OCRL OCRL1 Homo sapiens (Human) cilium assembly [GO:0060271]; in utero embryonic development [GO:0001701]; inositol phosphate metabolic process [GO:0043647]; lipid metabolic process [GO:0006629]; membrane organization [GO:0061024]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; regulation of GTPase activity [GO:0043087]; signal transduction [GO:0007165] clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; Golgi stack [GO:0005795]; Golgi-associated vesicle [GO:0005798]; lysosome [GO:0005764]; membrane [GO:0016020]; nucleus [GO:0005634]; phagocytic vesicle membrane [GO:0030670]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802] "GTPase activator activity [GO:0005096]; inositol phosphate phosphatase activity [GO:0052745]; inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity [GO:0052659]; inositol-1,4,5-trisphosphate 5-phosphatase activity [GO:0052658]; inositol-polyphosphate 5-phosphatase activity [GO:0004445]; phosphatidylinositol phosphate 4-phosphatase activity [GO:0034596]; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity [GO:0034485]; phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity [GO:0043813]; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity [GO:0004439]; small GTPase binding [GO:0031267]" 0.96955 -3.43 FIPTYKYDSK 0 0 10.3665 0 0 0 0 11.5104 11.5751 10.9185 10.984 0 11.2313 11.1677 11.4472 12.1965 11.6325 0 11.8916 11.2473 0 11.0877 11.0156 11.1606 0 0 10.4312 Q01970 PLCB3_HUMAN "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-3) (Phospholipase C-beta-3) (PLC-beta-3)" PLCB3 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; lipid catabolic process [GO:0016042]; phosphatidylinositol metabolic process [GO:0046488]; phosphatidylinositol-mediated signaling [GO:0048015]; regulation of systemic arterial blood pressure [GO:0003073]; release of sequestered calcium ion into cytosol [GO:0051209] cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; protein-containing complex [GO:0032991] cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; molecular adaptor activity [GO:0060090]; molecular function activator activity [GO:0140677]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipase C activity [GO:0004629] 0.84967 0.11564 IAAFEEGGK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.03719 9.37175 0 9.76328 0 0 9.74359 0 0 9.69159 9.62244 0 10.8842 11.2431 Q02040 AK17A_HUMAN "A-kinase anchor protein 17A (AKAP-17A) (721P) (B-lymphocyte antigen) (Protein XE7) (Protein kinase A-anchoring protein 17A) (PRKA17A) (Splicing factor, arginine/serine-rich 17A)" AKAP17A CXYorf3 DXYS155E SFRS17A XE7 Homo sapiens (Human) B cell activation [GO:0042113]; mRNA processing [GO:0006397]; regulation of DNA-templated transcription [GO:0006355]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]; signal transduction [GO:0007165] cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681] protein kinase A binding [GO:0051018]; RNA binding [GO:0003723] 0.96929 -4.9389 AVACNIKVSFDSTK 0 0 0 0 0 9.80323 0 0 0 0 0 0 0 0 0 9.28981 0 9.92767 0 10.4093 10.4088 10.1035 0 0 9.26615 0 0 Q02080 MEF2B_HUMAN Myocyte-specific enhancer factor 2B (RSRFR2) (Serum response factor-like protein 2) MEF2B XMEF2 Homo sapiens (Human) cell differentiation [GO:0030154]; heart development [GO:0007507]; muscle organ development [GO:0007517]; positive regulation of transcription by RNA polymerase II [GO:0045944] cell junction [GO:0030054]; chromatin [GO:0000785]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone deacetylase binding [GO:0042826]; protein dimerization activity [GO:0046983]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.28571 0.82578 TPPPLYLPTEGRR 0 0 0 0 0 0 0 0 0 11.7338 0 11.6897 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q02108 GCYA1_HUMAN Guanylate cyclase soluble subunit alpha-1 (GCS-alpha-1) (EC 4.6.1.2) (Guanylate cyclase soluble subunit alpha-3) (GCS-alpha-3) (Soluble guanylate cyclase large subunit) GUCY1A1 GUC1A3 GUCSA3 GUCY1A3 Homo sapiens (Human) "blood circulation [GO:0008015]; cGMP biosynthetic process [GO:0006182]; cGMP-mediated signaling [GO:0019934]; nitric oxide mediated signal transduction [GO:0007263]; nitric oxide-cGMP-mediated signaling pathway [GO:0038060]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; regulation of blood pressure [GO:0008217]; relaxation of vascular associated smooth muscle [GO:0060087]; response to oxygen levels [GO:0070482]; retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission [GO:0098925]" "cytosol [GO:0005829]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; guanylate cyclase complex, soluble [GO:0008074]" GTP binding [GO:0005525]; guanylate cyclase activity [GO:0004383]; heme binding [GO:0020037]; signaling receptor activity [GO:0038023] 0.93224 -1.2739 ESRKSLER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.871 9.38409 0 0 0 0 9.07342 0 0 0 Q02153 GCYB1_HUMAN Guanylate cyclase soluble subunit beta-1 (GCS-beta-1) (EC 4.6.1.2) (Guanylate cyclase soluble subunit beta-3) (GCS-beta-3) (Soluble guanylate cyclase small subunit) GUCY1B1 GUC1B3 GUCSB3 GUCY1B3 Homo sapiens (Human) "blood circulation [GO:0008015]; cellular response to nitric oxide [GO:0071732]; cGMP biosynthetic process [GO:0006182]; cGMP-mediated signaling [GO:0019934]; nitric oxide mediated signal transduction [GO:0007263]; nitric oxide-cGMP-mediated signaling pathway [GO:0038060]; response to oxygen levels [GO:0070482]; trans-synaptic signaling by nitric oxide, modulating synaptic transmission [GO:0099555]" "cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; guanylate cyclase complex, soluble [GO:0008074]; presynaptic active zone cytoplasmic component [GO:0098831]" adenylate cyclase activity [GO:0004016]; cytidylate cyclase activity [GO:0047805]; GTP binding [GO:0005525]; guanylate cyclase activity [GO:0004383]; heme binding [GO:0020037]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023] 0.91734 -0.85274 KEAQLDEEGQFLVR 0 0 0 0 0 0 0 0 9.42549 0 0 0 0 10.7615 0 0 0 0 0 0 0 0 0 0 0 0 0 Q02156 KPCE_HUMAN Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon) PRKCE PKCE Homo sapiens (Human) "apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell-substrate adhesion [GO:0031589]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to prostaglandin E stimulus [GO:0071380]; establishment of localization in cell [GO:0051649]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; insulin secretion [GO:0030073]; intracellular signal transduction [GO:0035556]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; locomotory exploration behavior [GO:0035641]; macrophage activation involved in immune response [GO:0002281]; MAPK cascade [GO:0000165]; mucus secretion [GO:0070254]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of cellular glucuronidation [GO:2001031]; positive regulation of cytokinesis [GO:0032467]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of insulin secretion [GO:0032024]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mucus secretion [GO:0070257]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; response to morphine [GO:0043278]; signal transduction [GO:0007165]; synaptic transmission, GABAergic [GO:0051932]; TRAM-dependent toll-like receptor 4 signaling pathway [GO:0035669]" cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; intermediate filament cytoskeleton [GO:0045111]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202] 14-3-3 protein binding [GO:0071889]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein kinase C activity [GO:0004698]; calcium-independent protein kinase C activity [GO:0004699]; enzyme activator activity [GO:0008047]; enzyme binding [GO:0019899]; ethanol binding [GO:0035276]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein kinase C activity [GO:0004697]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; signaling receptor activator activity [GO:0030546] 0.94007 -1.2998 FMATYLR 0 0 0 11.0819 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q02218 ODO1_HUMAN "2-oxoglutarate dehydrogenase complex component E1 (E1o) (OGDC-E1) (OGDH-E1) (EC 1.2.4.2) (2-oxoglutarate dehydrogenase, mitochondrial) (Alpha-ketoglutarate dehydrogenase) (Alpha-KGDH-E1) (Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase)" OGDH Homo sapiens (Human) 2-oxoglutarate metabolic process [GO:0006103]; cerebellar cortex development [GO:0021695]; generation of precursor metabolites and energy [GO:0006091]; glycolytic process [GO:0006096]; hippocampus development [GO:0021766]; histone succinylation [GO:0106077]; NADH metabolic process [GO:0006734]; olfactory bulb mitral cell layer development [GO:0061034]; pyramidal neuron development [GO:0021860]; striatum development [GO:0021756]; succinyl-CoA metabolic process [GO:0006104]; tangential migration from the subventricular zone to the olfactory bulb [GO:0022028]; thalamus development [GO:0021794]; tricarboxylic acid cycle [GO:0006099] mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; oxoglutarate dehydrogenase complex [GO:0045252] heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; oxoglutarate dehydrogenase (NAD+) activity [GO:0034602]; oxoglutarate dehydrogenase (succinyl-transferring) activity [GO:0004591]; protein-folding chaperone binding [GO:0051087]; thiamine pyrophosphate binding [GO:0030976] 0.96974 -4.7471 INRVTDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.05561 0 0 0 0 0 0 0 0 9.82749 0 0 Q02221 CX6A2_HUMAN "Cytochrome c oxidase subunit 6A2, mitochondrial (Cytochrome c oxidase polypeptide VIa-heart) (COXVIAH) (Cytochrome c oxidase subunit VIA-muscle) (COX VIa-M)" COX6A2 COX6A COX6AH Homo sapiens (Human) "generation of precursor metabolites and energy [GO:0006091]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]" mitochondrial respiratory chain complex IV [GO:0005751] enzyme regulator activity [GO:0030234]; oxidoreductase activity [GO:0016491] 0.96195 -2.5603 GLASAAK 0 0 0 0 0 0 0 0 0 0 11.0257 0 0 0 9.55697 0 0 0 9.23618 0 0 0 0 0 0 0 0 Q02224 CENPE_HUMAN Centromere-associated protein E (Centromere protein E) (CENP-E) (Kinesin-7) (Kinesin-related protein CENPE) CENPE Homo sapiens (Human) attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; kinetochore assembly [GO:0051382]; lateral attachment of mitotic spindle microtubules to kinetochore [GO:0099607]; metaphase plate congression [GO:0051310]; microtubule plus-end directed mitotic chromosome migration [GO:0099606]; microtubule-based movement [GO:0007018]; mitotic cell cycle [GO:0000278]; mitotic chromosome movement towards spindle pole [GO:0007079]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle organization [GO:0007052]; positive regulation of protein kinase activity [GO:0045860]; regulation of mitotic metaphase/anaphase transition [GO:0030071] "chromosome [GO:0005694]; chromosome, centromeric region [GO:0000775]; condensed chromosome, centromeric region [GO:0000779]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; intracellular membrane-bounded organelle [GO:0043231]; kinetochore [GO:0000776]; kinetochore microtubule [GO:0005828]; membrane [GO:0016020]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; mitotic spindle midzone [GO:1990023]; nucleus [GO:0005634]; spindle midzone [GO:0051233]" ATP binding [GO:0005524]; kinetochore binding [GO:0043515]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777] 0.9682 -9.5223 DLEHSNDALKAQDLK 0 0 0 0 0 0 0 10.1648 0 0 10.8785 12.7327 0 0 9.36181 10.0434 9.89235 11.0167 0 0 11.3503 10.1319 10.4627 0 0 10.9326 0 Q02241 KIF23_HUMAN Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1) KIF23 KNSL5 MKLP1 Homo sapiens (Human) microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle elongation [GO:0000022]; mitotic spindle midzone assembly [GO:0051256]; positive regulation of cytokinesis [GO:0032467] centralspindlin complex [GO:0097149]; centrosome [GO:0005813]; cytosol [GO:0005829]; Flemming body [GO:0090543]; focal adhesion [GO:0005925]; kinesin complex [GO:0005871]; microtubule [GO:0005874]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777] 0.92407 -1.0463 ECERRVAAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2119 0 9.922 0 0 0 0 0 0 Q02246 CNTN2_HUMAN Contactin-2 (Axonal glycoprotein TAG-1) (Axonin-1) (Transient axonal glycoprotein 1) (TAX-1) CNTN2 AXT TAG1 TAX1 Homo sapiens (Human) adult walking behavior [GO:0007628]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cerebral cortex GABAergic interneuron migration [GO:0021853]; clustering of voltage-gated potassium channels [GO:0045163]; dendrite self-avoidance [GO:0070593]; establishment of localization in cell [GO:0051649]; establishment of protein localization to juxtaparanode region of axon [GO:0071206]; fat cell differentiation [GO:0045444]; G protein-coupled adenosine receptor signaling pathway [GO:0001973]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; learning [GO:0007612]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; positive regulation of protein processing [GO:0010954]; presynaptic membrane organization [GO:0097090]; protein localization to juxtaparanode region of axon [GO:0071205]; protein processing [GO:0016485]; receptor internalization [GO:0031623]; reduction of food intake in response to dietary excess [GO:0002023]; regulation of astrocyte differentiation [GO:0048710]; regulation of axon diameter [GO:0031133]; regulation of cell morphogenesis involved in differentiation [GO:0010769]; regulation of neuronal synaptic plasticity [GO:0048168] axon [GO:0030424]; axon initial segment [GO:0043194]; cell surface [GO:0009986]; juxtaparanode region of axon [GO:0044224]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; node of Ranvier [GO:0033268]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202] carbohydrate binding [GO:0030246]; cell-cell adhesion mediator activity [GO:0098632]; protein self-association [GO:0043621] 0.89935 -0.64124 ETIGDLTILNAQLRHGGK 0 0 0 9.0617 0 9.307 0 0 0 0 0 0 0 0 0 0 0 0 9.18673 0 0 0 0 0 10.2978 0 0 Q02297 NRG1_HUMAN "Pro-neuregulin-1, membrane-bound isoform (Pro-NRG1) [Cleaved into: Neuregulin-1 (Acetylcholine receptor-inducing activity) (ARIA) (Breast cancer cell differentiation factor p45) (Glial growth factor) (Heregulin) (HRG) (Neu differentiation factor) (Sensory and motor neuron-derived factor)]" NRG1 GGF HGL HRGA NDF SMDF Homo sapiens (Human) activation of protein kinase B activity [GO:0032148]; activation of transmembrane receptor protein tyrosine kinase activity [GO:0007171]; animal organ development [GO:0048513]; cardiac muscle cell differentiation [GO:0055007]; cardiac muscle cell myoblast differentiation [GO:0060379]; cell communication [GO:0007154]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; endocardial cell differentiation [GO:0060956]; ERBB signaling pathway [GO:0038127]; ERBB2-ERBB3 signaling pathway [GO:0038133]; ERBB2-ERBB4 signaling pathway [GO:0038135]; ERBB3 signaling pathway [GO:0038129]; ERBB4 signaling pathway [GO:0038130]; ERBB4-ERBB4 signaling pathway [GO:0038138]; intracellular signal transduction [GO:0035556]; mammary gland development [GO:0030879]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of secretion [GO:0051048]; nervous system development [GO:0007399]; neural crest cell development [GO:0014032]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of protein-containing complex assembly [GO:0031334]; positive regulation of striated muscle cell differentiation [GO:0051155]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; sequestering of metal ion [GO:0051238]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ventricular cardiac muscle cell differentiation [GO:0055012]; ventricular trabecula myocardium morphogenesis [GO:0003222]; wound healing [GO:0042060] apical plasma membrane [GO:0016324]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] chemorepellent activity [GO:0045499]; cytokine activity [GO:0005125]; ErbB-3 class receptor binding [GO:0043125]; growth factor activity [GO:0008083]; integrin binding [GO:0005178]; protein tyrosine kinase activator activity [GO:0030296]; receptor ligand activity [GO:0048018]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102]; transcription coregulator activity [GO:0003712]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297] 0.87107 0.048619 TFCVNGGECFMVK 0 0 0 0 0 8.8715 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q02318 CP27A_HUMAN "Sterol 26-hydroxylase, mitochondrial (EC 1.14.15.15) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 26-hydroxylase) (Cytochrome P-450C27/25) (Cytochrome P450 27) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase)" CYP27A1 CYP27 Homo sapiens (Human) bile acid biosynthetic process [GO:0006699]; calcitriol biosynthetic process from calciol [GO:0036378]; cholesterol catabolic process [GO:0006707]; cholesterol metabolic process [GO:0008203]; sterol metabolic process [GO:0016125] mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] "3-alpha,7-alpha,12-alpha-trihydroxycholestan-26-al 26-oxidoreductase activity [GO:0047103]; cholestanetetraol 26-dehydrogenase activity [GO:0047748]; cholestanetriol 26-monooxygenase activity [GO:0047749]; cholesterol 26-hydroxylase activity [GO:0031073]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; steroid hydroxylase activity [GO:0008395]; vitamin D3 25-hydroxylase activity [GO:0030343]" 0.7302 0.33239 AAIPAALPSDK 0 0 0 8.76378 0 0 0 0 0 0 0 9.34773 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q02338 BDH_HUMAN "D-beta-hydroxybutyrate dehydrogenase, mitochondrial (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase) (BDH) (Short chain dehydrogenase/reductase family 9C member 1)" BDH1 BDH SDR9C1 Homo sapiens (Human) steroid metabolic process [GO:0008202] intracellular membrane-bounded organelle [GO:0043231]; matrix side of mitochondrial inner membrane [GO:0099617]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] 3-hydroxybutyrate dehydrogenase activity [GO:0003858] 0 17.917 MWEELPEVVR 0 0 0 9.37417 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.19399 0 0 11.7822 10.9221 10.833 Q02383 SEMG2_HUMAN Semenogelin-2 (Semenogelin II) (SGII) SEMG2 Homo sapiens (Human) antibacterial humoral response [GO:0019731]; coagulation [GO:0050817]; negative regulation of flagellated sperm motility [GO:1901318]; positive regulation of serine-type endopeptidase activity [GO:1900005]; sperm capacitation [GO:0048240] extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634] protease binding [GO:0002020]; zinc ion binding [GO:0008270] 0.88145 -0.30641 DIFTTQDELLVYNK 9.43237 0 0 0 0 0 0 0 0 0 0 11.9351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q02388 CO7A1_HUMAN Collagen alpha-1(VII) chain (Long-chain collagen) (LC collagen) COL7A1 Homo sapiens (Human) cell adhesion [GO:0007155]; endodermal cell differentiation [GO:0035987]; epidermis development [GO:0008544]; extracellular matrix organization [GO:0030198]; negative regulation of peptidase activity [GO:0010466] basement membrane [GO:0005604]; collagen type VII trimer [GO:0005590]; collagen-containing extracellular matrix [GO:0062023]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020]; serine-type endopeptidase inhibitor activity [GO:0004867] 0.96852 -3.6032 DGLPGLR 0 13.2083 0 0 0 0 0 0 0 0 0 0 0 9.79515 0 10.6908 0 0 0 0 0 0 0 0 0 0 0 Q02487 DSC2_HUMAN Desmocollin-2 (Cadherin family member 2) (Desmocollin-3) (Desmosomal glycoprotein II) (Desmosomal glycoprotein III) DSC2 CDHF2 DSC3 Homo sapiens (Human) bundle of His cell-Purkinje myocyte adhesion involved in cell communication [GO:0086073]; cardiac muscle cell-cardiac muscle cell adhesion [GO:0086042]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cellular response to starvation [GO:0009267]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ventricular cardiac muscle cell action potential [GO:0098911] adherens junction [GO:0005912]; cornified envelope [GO:0001533]; cytoplasmic vesicle [GO:0031410]; desmosome [GO:0030057]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; intercalated disc [GO:0014704]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication [GO:0086083] 0.91596 -0.77373 TLAEACMKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1252 0 0 0 0 0 Q02535 ID3_HUMAN DNA-binding protein inhibitor ID-3 (Class B basic helix-loop-helix protein 25) (bHLHb25) (Helix-loop-helix protein HEIR-1) (ID-like protein inhibitor HLH 1R21) (Inhibitor of DNA binding 3) (Inhibitor of differentiation 3) ID3 1R21 BHLHB25 HEIR1 Homo sapiens (Human) cell differentiation [GO:0030154]; cellular response to leptomycin B [GO:0072750]; central nervous system development [GO:0007417]; circadian regulation of gene expression [GO:0032922]; epithelial cell differentiation [GO:0030855]; heart development [GO:0007507]; metanephros development [GO:0001656]; muscle organ development [GO:0007517]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; notochord development [GO:0030903]; odontogenesis [GO:0042476]; positive regulation of apoptotic process [GO:0043065]; positive regulation of gene expression [GO:0010628]; regulation of cell cycle [GO:0051726]; regulation of DNA replication [GO:0006275]; response to wounding [GO:0009611] cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] bHLH transcription factor binding [GO:0043425]; leptomycin B binding [GO:1901707]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; transcription regulator inhibitor activity [GO:0140416] 0.86893 0.068711 GCYEAVCCLSER 10.3606 0 0 0 0 0 0 9.57061 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q02543 RL18A_HUMAN Large ribosomal subunit protein eL20 (60S ribosomal protein L18a) RPL18A Homo sapiens (Human) cytoplasmic translation [GO:0002181]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; membrane [GO:0016020]; polysomal ribosome [GO:0042788] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.87058 0.063747 DLTTAGAVTQCYR 9.54433 0 9.41981 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q02548 PAX5_HUMAN Paired box protein Pax-5 (B-cell-specific transcription factor) (BSAP) PAX5 Homo sapiens (Human) adult behavior [GO:0030534]; anatomical structure development [GO:0048856]; B cell differentiation [GO:0030183]; cerebral cortex development [GO:0021987]; embryonic cranial skeleton morphogenesis [GO:0048701]; lateral ventricle development [GO:0021670]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal muscle cell differentiation [GO:0035914]; spermatogenesis [GO:0007283]; transcription by RNA polymerase II [GO:0006366] chromatin [GO:0000785]; nucleoplasm [GO:0005654] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; molecular adaptor activity [GO:0060090]; nucleic acid binding [GO:0003676]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.95877 -1.7781 GAAPPAAATAYDR 0 0 0 0 0 0 0 0 0 0 9.10407 0 9.88209 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q02556 IRF8_HUMAN Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence-binding protein) (H-ICSBP) (ICSBP) IRF8 ICSBP1 Homo sapiens (Human) autophagy [GO:0006914]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; dendritic cell differentiation [GO:0097028]; follicular B cell differentiation [GO:0002316]; germinal center B cell differentiation [GO:0002314]; immune response [GO:0006955]; immune system process [GO:0002376]; myeloid cell differentiation [GO:0030099]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phagocytosis [GO:0006909]; plasmacytoid dendritic cell differentiation [GO:0002273]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type II interferon production [GO:0032729]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of type I interferon production [GO:0032479] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.82072 0.21682 IVPEEEQK 0 0 0 0 0 10.295 0 0 10.756 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q02750 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (MKK1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1) MAP2K1 MEK1 PRKMK1 Homo sapiens (Human) Bergmann glial cell differentiation [GO:0060020]; cell motility [GO:0048870]; cellular senescence [GO:0090398]; cerebellar cortex formation [GO:0021697]; chemotaxis [GO:0006935]; endodermal cell differentiation [GO:0035987]; epithelial cell proliferation involved in lung morphogenesis [GO:0060502]; ERK1 and ERK2 cascade [GO:0070371]; face development [GO:0060324]; heart development [GO:0007507]; insulin-like growth factor receptor signaling pathway [GO:0048009]; keratinocyte differentiation [GO:0030216]; labyrinthine layer development [GO:0060711]; MAPK cascade [GO:0000165]; negative regulation of cell population proliferation [GO:0008285]; neuron differentiation [GO:0030182]; placenta blood vessel development [GO:0060674]; positive regulation of axonogenesis [GO:0050772]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endodermal cell differentiation [GO:1903226]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein phosphorylation [GO:0006468]; regulation of axon regeneration [GO:0048679]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of Golgi inheritance [GO:0090170]; regulation of stress-activated MAPK cascade [GO:0032872]; signal transduction [GO:0007165]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; trachea formation [GO:0060440]; type B pancreatic cell proliferation [GO:0044342] cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; microtubule organizing center [GO:0005815]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; MAP kinase kinase activity [GO:0004708]; MAP-kinase scaffold activity [GO:0005078]; protein kinase activator activity [GO:0030295]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activator activity [GO:0043539]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110] 0.88819 -0.40623 KLEELELDEQQR 9.39656 9.01906 0 0 0 0 9.47243 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1591 0 0 Q02763 TIE2_HUMAN Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b) TEK TIE2 VMCM VMCM1 Homo sapiens (Human) angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; definitive hemopoiesis [GO:0060216]; endothelial cell proliferation [GO:0001935]; glomerulus vasculature development [GO:0072012]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; intracellular signal transduction [GO:0035556]; negative regulation of angiogenesis [GO:0016525]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of inflammatory response [GO:0050728]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; protein autophosphorylation [GO:0046777]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment or maintenance of cell polarity [GO:0032878]; regulation of vascular permeability [GO:0043114]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; substrate adhesion-dependent cell spreading [GO:0034446]; Tie signaling pathway [GO:0048014]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; centriolar satellite [GO:0034451]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; membrane raft [GO:0045121]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] ATP binding [GO:0005524]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]; protein tyrosine kinase activity [GO:0004713]; signaling receptor activity [GO:0038023]; transmembrane receptor protein tyrosine kinase activity [GO:0004714] 0.94726 -1.3477 RANVQRR 0 0 0 11.4631 0 11.9263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q02779 M3K10_HUMAN Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) MAP3K10 MLK2 MST Homo sapiens (Human) apoptotic process [GO:0006915]; JNK cascade [GO:0007254]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of apoptotic process [GO:0043065]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; protein autophosphorylation [GO:0046777]; signal transduction [GO:0007165]; smoothened signaling pathway [GO:0007224] cytoplasm [GO:0005737] ATP binding [GO:0005524]; bHLH transcription factor binding [GO:0043425]; JUN kinase kinase kinase activity [GO:0004706]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; transcription corepressor activity [GO:0003714] 0.96948 -4.9764 GLGEGSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.029 0 0 0 0 10.0034 0 0 0 0 0 Q02790 FKBP4_HUMAN "Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) (EC 5.2.1.8) (51 kDa FK506-binding protein) (FKBP51) (52 kDa FK506-binding protein) (52 kDa FKBP) (FKBP-52) (59 kDa immunophilin) (p59) (FK506-binding protein 4) (FKBP-4) (FKBP59) (HSP-binding immunophilin) (HBI) (Immunophilin FKBP52) (Rotamase) [Cleaved into: Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed]" FKBP4 FKBP52 Homo sapiens (Human) androgen receptor signaling pathway [GO:0030521]; chaperone-mediated protein folding [GO:0061077]; copper ion transport [GO:0006825]; embryo implantation [GO:0007566]; male sex differentiation [GO:0046661]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977]; prostate gland development [GO:0030850]; protein folding [GO:0006457]; protein-containing complex localization [GO:0031503]; steroid hormone receptor complex assembly [GO:0006463] axonal growth cone [GO:0044295]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991] ATP binding [GO:0005524]; copper-dependent protein binding [GO:0032767]; FK506 binding [GO:0005528]; GTP binding [GO:0005525]; heat shock protein binding [GO:0031072]; nuclear glucocorticoid receptor binding [GO:0035259]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; protein-macromolecule adaptor activity [GO:0030674]; RNA binding [GO:0003723]; tau protein binding [GO:0048156] 0.18354 0.9501 AWDIAIATMK 0 0 0 0 0 0 0 0 0 10.9663 8.89321 0 0 0 0 10.6289 0 0 0 8.85387 0 0 0 0 10.7571 0 0 Q02817 MUC2_HUMAN Mucin-2 (MUC-2) (Intestinal mucin-2) MUC2 SMUC Homo sapiens (Human) detoxification of copper ion [GO:0010273]; host-mediated regulation of intestinal microbiota composition [GO:0048874]; maintenance of gastrointestinal epithelium [GO:0030277]; mucus secretion [GO:0070254] collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; inner mucus layer [GO:0070702]; outer mucus layer [GO:0070703]; plasma membrane [GO:0005886] cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136] 0.96949 -3.5166 AGLTLMWNR 9.84463 11.0715 0 0 0 0 0 9.7048 0 10.3593 9.56425 10.1435 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q02818 NUCB1_HUMAN Nucleobindin-1 (CALNUC) NUCB1 NUC Homo sapiens (Human) small GTPase mediated signal transduction [GO:0007264] endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020] calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; G-protein alpha-subunit binding [GO:0001965]; guanyl-nucleotide exchange factor activity [GO:0005085] 0.93998 -1.3019 DLAQYDAAHHEEFKRYEMLK 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0749 0 0 10.8832 0 0 0 0 0 9.77038 0 12.0015 0 0 Q02878 RL6_HUMAN Large ribosomal subunit protein eL6 (60S ribosomal protein L6) (Neoplasm-related protein C140) (Tax-responsive enhancer element-binding protein 107) (TaxREB107) RPL6 TXREB1 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; regulation of DNA-templated transcription [GO:0006355]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412] cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; polysomal ribosome [GO:0042788]; postsynaptic density [GO:0014069]; rough endoplasmic reticulum [GO:0005791] cadherin binding [GO:0045296]; DNA binding [GO:0003677]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0 3.3102 AIPQLQGYLR 0 0 9.80352 9.09719 0 0 10.9673 10.8386 10.9416 11.0828 0 0 8.66092 0 8.72928 9.18306 8.61412 10.2174 0 0 0 9.79049 0 10.5665 0 9.8197 0 Q02880 TOP2B_HUMAN "DNA topoisomerase 2-beta (EC 5.6.2.2) (DNA topoisomerase II, beta isozyme)" TOP2B Homo sapiens (Human) axonogenesis [GO:0007409]; B cell differentiation [GO:0030183]; DNA topological change [GO:0006265]; forebrain development [GO:0030900]; neuron migration [GO:0001764]; positive regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045870]; resolution of meiotic recombination intermediates [GO:0000712]; sister chromatid segregation [GO:0000819] cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] "ATP binding [GO:0005524]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; enzyme binding [GO:0019899]; metal ion binding [GO:0046872]" 0.96987 -4.2723 FTVETACKEYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6102 0 0 0 0 0 0 0 0 0 Q02952 AKA12_HUMAN A-kinase anchor protein 12 (AKAP-12) (A-kinase anchor protein 250 kDa) (AKAP 250) (Gravin) (Myasthenia gravis autoantigen) AKAP12 AKAP250 Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; G protein-coupled receptor signaling pathway [GO:0007186]; hepatic stellate cell activation [GO:0035733]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of vascular permeability [GO:0043116]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hepatic stellate cell migration [GO:0061870]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of oligodendrocyte apoptotic process [GO:1900143]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of protein kinase A signaling [GO:0010738]; regulation of protein kinase C signaling [GO:0090036]; response to electrical stimulus [GO:0051602]; response to lipopolysaccharide [GO:0032496]; signal transduction [GO:0007165] cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685] adenylate cyclase binding [GO:0008179]; calmodulin binding [GO:0005516]; protein kinase A binding [GO:0051018] 0.95548 -1.6346 ERPPAPSSFVFQEETKEQSK 0 11.5486 0 0 0 0 0 11.13 0 0 11.4197 0 0 0 0 0 0 0 9.22846 0 0 0 0 0 0 0 9.47344 Q02978 M2OM_HUMAN Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP) (alpha-oxoglutarate carrier) (Solute carrier family 25 member 11) (SLC25A11) SLC25A11 SLC20A4 Homo sapiens (Human) gluconeogenesis [GO:0006094]; lipid transport [GO:0006869]; malate transmembrane transport [GO:0071423]; oxaloacetate transport [GO:0015729]; phosphate ion transmembrane transport [GO:0035435]; succinate transmembrane transport [GO:0071422]; sulfate transport [GO:0008272]; thiosulfate transport [GO:0015709] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886] antiporter activity [GO:0015297]; malate transmembrane transporter activity [GO:0015140]; oxaloacetate transmembrane transporter activity [GO:0015131]; oxoglutarate:malate antiporter activity [GO:0015367]; RNA binding [GO:0003723]; succinate transmembrane transporter activity [GO:0015141]; sulfate transmembrane transporter activity [GO:0015116]; thiosulfate transmembrane transporter activity [GO:0015117] 0.95014 -1.3838 GFTPYYAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.21818 0 0 0 0 0 0 0 0 0 0 Q03001 DYST_HUMAN Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein) DST BP230 BP240 BPAG1 DMH DT KIAA0728 Homo sapiens (Human) cell adhesion [GO:0007155]; cell motility [GO:0048870]; cytoskeleton organization [GO:0007010]; hemidesmosome assembly [GO:0031581]; integrin-mediated signaling pathway [GO:0007229]; intermediate filament cytoskeleton organization [GO:0045104]; maintenance of cell polarity [GO:0030011]; microtubule cytoskeleton organization [GO:0000226]; response to wounding [GO:0009611]; retrograde axonal transport [GO:0008090]; wound healing [GO:0042060] actin cytoskeleton [GO:0015629]; axon [GO:0030424]; axon cytoplasm [GO:1904115]; basal plasma membrane [GO:0009925]; basement membrane [GO:0005604]; cell cortex [GO:0005938]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; focal adhesion [GO:0005925]; H zone [GO:0031673]; hemidesmosome [GO:0030056]; intermediate filament [GO:0005882]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; microtubule plus-end [GO:0035371]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Z disc [GO:0030018] actin binding [GO:0003779]; calcium ion binding [GO:0005509]; integrin binding [GO:0005178]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein homodimerization activity [GO:0042803]; structural molecule activity [GO:0005198] 0.96879 -10.874 AGNDLIESSAGEEASNLQNK 8.83039 0 0 0 0 0 0 0 10.527 0 0 0 10.5786 9.91262 0 0 0 9.49295 0 0 0 11.3049 12.1314 0 10.976 9.43041 11.6299 Q03013 GSTM4_HUMAN Glutathione S-transferase Mu 4 (EC 2.5.1.18) (GST class-mu 4) (GST-Mu2) (GSTM4-4) (Leukotriene C4 synthase GSTM4) (EC 4.4.1.20) GSTM4 Homo sapiens (Human) glutathione metabolic process [GO:0006749]; long-chain fatty acid biosynthetic process [GO:0042759]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178] cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171] enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; leukotriene-C4 synthase activity [GO:0004464]; protein homodimerization activity [GO:0042803] 0.89156 -0.50764 ISAYMKSSR 0 0 0 0 0 0 9.3439 0 0 0 0 0 0 0 0 0 0 0 10.9292 0 10.1408 0 0 0 0 0 10.9632 Q03052 PO3F1_HUMAN "POU domain, class 3, transcription factor 1 (Octamer-binding protein 6) (Oct-6) (Octamer-binding transcription factor 6) (OTF-6) (POU domain transcription factor SCIP)" POU3F1 OCT6 OTF6 Homo sapiens (Human) axon ensheathment [GO:0008366]; forebrain development [GO:0030900]; keratinocyte differentiation [GO:0030216]; myelination in peripheral nervous system [GO:0022011]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.89888 -0.56805 AGGGGTGR 0 0 0 0 0 0 0 0 0 0 9.25404 0 9.31129 0 9.24113 0 0 0 0 0 8.94778 0 0 0 0 0 0 Q03060 CREM_HUMAN cAMP-responsive element modulator (Inducible cAMP early repressor) (ICER) CREM Homo sapiens (Human) cell differentiation [GO:0030154]; glycosphingolipid metabolic process [GO:0006687]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283] ATF4-CREB1 transcription factor complex [GO:1990589]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleus [GO:0005634] "cAMP response element binding protein binding [GO:0008140]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.9392 -1.3185 ELRLMKNR 0 0 0 11.0819 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q03111 ENL_HUMAN Protein ENL (YEATS domain-containing protein 1) MLLT1 ENL LTG19 YEATS1 Homo sapiens (Human) negative regulation of protein kinase activity [GO:0006469]; positive regulation of DNA-templated transcription [GO:0045893] cytosol [GO:0005829]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; transcription elongation factor complex [GO:0008023] chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577] 0.96164 -2.0665 DTSRKLGEGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.5966 0 0 0 0 0 0 0 8.76815 0 0 13.2942 Q03112 MECOM_HUMAN Histone-lysine N-methyltransferase MECOM (EC 2.1.1.367) (Ecotropic virus integration site 1 protein homolog) (EVI-1) (MDS1 and EVI1 complex locus protein) (Myelodysplasia syndrome 1 protein) (Myelodysplasia syndrome-associated protein 1) MECOM EVI1 MDS1 PRDM3 Homo sapiens (Human) apoptotic process [GO:0006915]; hematopoietic stem cell proliferation [GO:0071425]; heterochromatin organization [GO:0070828]; methylation [GO:0032259]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of JNK cascade [GO:0046329]; negative regulation of programmed cell death [GO:0043069]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cell cycle [GO:0051726]; regulation of transcription by RNA polymerase II [GO:0006357] cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; histone H3K9 methyltransferase activity [GO:0046974]; histone H3K9 monomethyltransferase activity [GO:0140948]; histone H3K9me2 methyltransferase activity [GO:0140947]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96195 -2.4593 EDAYFTEIR 0 0 0 0 0 0 9.21827 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.61038 0 0 0 Q03113 GNA12_HUMAN Guanine nucleotide-binding protein subunit alpha-12 (G alpha-12) (G-protein subunit alpha-12) GNA12 Homo sapiens (Human) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; blood coagulation [GO:0007596]; cell differentiation [GO:0030154]; embryonic digit morphogenesis [GO:0042733]; G protein-coupled receptor signaling pathway [GO:0007186]; in utero embryonic development [GO:0001701]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; regulation of blood pressure [GO:0008217]; regulation of cell shape [GO:0008360]; regulation of fibroblast migration [GO:0010762]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; regulation of TOR signaling [GO:0032006]; response to xenobiotic stimulus [GO:0009410]; Rho protein signal transduction [GO:0007266] brush border membrane [GO:0031526]; cytoplasm [GO:0005737]; focal adhesion [GO:0005925]; heterotrimeric G-protein complex [GO:0005834]; lateral plasma membrane [GO:0016328]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886] D5 dopamine receptor binding [GO:0031752]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase regulator activity [GO:0019888] 0.96895 -4.4429 IPFKMVDVGGQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6918 8.95963 10.761 9.57355 0 0 0 0 Q03154 ACY1_HUMAN Aminoacylase-1 (ACY-1) (EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase) ACY1 Homo sapiens (Human) amino acid metabolic process [GO:0006520] cytosol [GO:0005829]; extracellular exosome [GO:0070062] aminoacylase activity [GO:0004046]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872] 0.88225 -0.079878 LEGGVAYNVIPATMSASFDFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.60663 0 0 Q03164 KMT2A_HUMAN Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.364) (ALL-1) (CXXC-type zinc finger protein 7) (Cysteine methyltransferase KMT2A) (EC 2.1.1.-) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Trithorax-like protein) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)] KMT2A ALL1 CXXC7 HRX HTRX MLL MLL1 TRX1 Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; circadian regulation of gene expression [GO:0032922]; definitive hemopoiesis [GO:0060216]; DNA methylation [GO:0006306]; embryonic hemopoiesis [GO:0035162]; exploration behavior [GO:0035640]; fibroblast proliferation [GO:0048144]; histone H3-K4 methylation [GO:0051568]; histone H3-K4 trimethylation [GO:0080182]; homeostasis of number of cells within a tissue [GO:0048873]; membrane depolarization [GO:0051899]; negative regulation of DNA methylation [GO:1905642]; negative regulation of fibroblast proliferation [GO:0048147]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transporter activity [GO:0032411]; post-embryonic development [GO:0009791]; protein-containing complex assembly [GO:0065003]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to potassium ion [GO:0035864]; spleen development [GO:0048536]; T-helper 2 cell differentiation [GO:0045064]; transcription initiation-coupled chromatin remodeling [GO:0045815]; visual learning [GO:0008542] cytosol [GO:0005829]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; histone H3K4 methyltransferase activity [GO:0042800]; histone H3K4 monomethyltransferase activity [GO:0140945]; histone H3K4 trimethyltransferase activity [GO:0140999]; identical protein binding [GO:0042802]; lysine-acetylated histone binding [GO:0070577]; minor groove of adenine-thymine-rich DNA binding [GO:0003680]; protein homodimerization activity [GO:0042803]; protein-cysteine methyltransferase activity [GO:0106363]; unmethylated CpG binding [GO:0045322]; zinc ion binding [GO:0008270] 0.96394 -2.205 AKNCVFLDDK 0 0 10.8958 0 0 10.631 0 10.1657 8.52485 0 8.24374 0 0 0 0 0 0 0 0 9.5328 0 10.3209 0 0 0 10.9097 9.75104 Q03169 TNAP2_HUMAN Tumor necrosis factor alpha-induced protein 2 (TNF alpha-induced protein 2) (Primary response gene B94 protein) TNFAIP2 Homo sapiens (Human) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; exocyst localization [GO:0051601]; exocytosis [GO:0006887] exocyst [GO:0000145]; extracellular space [GO:0005615] SNARE binding [GO:0000149] 0.83528 0.19628 AFNEFLER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.7622 9.54297 0 0 0 0 0 0 0 0 0 0 0 Q03181 PPARD_HUMAN Peroxisome proliferator-activated receptor delta (PPAR-delta) (NUCI) (Nuclear hormone receptor 1) (NUC1) (Nuclear receptor subfamily 1 group C member 2) (Peroxisome proliferator-activated receptor beta) (PPAR-beta) PPARD NR1C2 PPARB Homo sapiens (Human) adipose tissue development [GO:0060612]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; axon ensheathment [GO:0008366]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell-substrate adhesion [GO:0031589]; cellular response to hypoxia [GO:0071456]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cholesterol metabolic process [GO:0008203]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; energy homeostasis [GO:0097009]; fat cell proliferation [GO:0070341]; fatty acid beta-oxidation [GO:0006635]; fatty acid catabolic process [GO:0009062]; fatty acid transport [GO:0015908]; generation of precursor metabolites and energy [GO:0006091]; glucose metabolic process [GO:0006006]; glucose transmembrane transport [GO:1904659]; heart development [GO:0007507]; hormone-mediated signaling pathway [GO:0009755]; keratinocyte migration [GO:0051546]; keratinocyte proliferation [GO:0043616]; lipid metabolic process [GO:0006629]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of inflammatory response [GO:0050728]; negative regulation of miRNA transcription [GO:1902894]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phospholipid biosynthetic process [GO:0008654]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epidermis development [GO:0045684]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of fat cell proliferation [GO:0070346]; positive regulation of fatty acid oxidation [GO:0046321]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of myoblast proliferation [GO:2000288]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of skeletal muscle tissue regeneration [GO:0043415]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteoglycan metabolic process [GO:0006029]; regulation of lipid metabolic process [GO:0019216]; regulation of skeletal muscle satellite cell proliferation [GO:0014842]; regulation of transcription by RNA polymerase II [GO:0006357]; response to activity [GO:0014823]; response to glucose [GO:0009749]; response to vitamin A [GO:0033189]; vasodilation [GO:0042311]; vitamin A metabolic process [GO:0006776]; wound healing [GO:0042060] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription factor binding [GO:0140297]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; linoleic acid binding [GO:0070539]; lipid binding [GO:0008289]; NF-kappaB binding [GO:0051059]; nuclear receptor activity [GO:0004879]; nuclear steroid receptor activity [GO:0003707]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]" 0.82586 0.2122 EISVHVFYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7399 0 0 0 0 0 0 0 0 0 0 0 0 Q03188 CENPC_HUMAN Centromere protein C (CENP-C) (Centromere autoantigen C) (Centromere protein C 1) (CENP-C 1) (Interphase centromere complex protein 7) CENPC CENPC1 ICEN7 Homo sapiens (Human) attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; kinetochore assembly [GO:0051382]; mitotic cell cycle [GO:0000278]; monopolar spindle attachment to meiosis I kinetochore [GO:0051455] "condensed chromosome, centromeric region [GO:0000779]; cytosol [GO:0005829]; kinetochore [GO:0000776]; midbody [GO:0030496]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; pericentric heterochromatin [GO:0005721]" centromeric DNA binding [GO:0019237]; DNA binding [GO:0003677]; identical protein binding [GO:0042802] 0.89799 -0.63225 AGSLKQR 0 0 0 0 10.5634 0 0 11.0969 12.163 0 0 0 0 0 0 13.3718 9.58731 0 0 9.40297 0 10.2004 0 0 0 0 0 Q03252 LMNB2_HUMAN Lamin-B2 LMNB2 LMN2 Homo sapiens (Human) heterochromatin formation [GO:0031507]; nuclear envelope organization [GO:0006998]; nuclear migration [GO:0007097]; nuclear pore localization [GO:0051664]; protein localization to nuclear envelope [GO:0090435] intermediate filament [GO:0005882]; nuclear envelope [GO:0005635]; nuclear lamina [GO:0005652]; nuclear membrane [GO:0031965] identical protein binding [GO:0042802]; structural constituent of cytoskeleton [GO:0005200] 0.96976 -4.3321 EEVTTREVSGIK 0 0 0 0 8.98034 0 0 0 0 0 0 0 9.65973 0 0 0 0 0 0 0 9.91504 9.63972 9.63849 0 0 11.1102 0 Q03395 ROM1_HUMAN Rod outer segment membrane protein 1 (ROSP1) (Tetraspanin-23) (Tspan-23) ROM1 TSPAN23 Homo sapiens (Human) camera-type eye photoreceptor cell differentiation [GO:0060219]; cell adhesion [GO:0007155]; detection of light stimulus involved in visual perception [GO:0050908]; photoreceptor cell outer segment organization [GO:0035845]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; protein localization to photoreceptor outer segment [GO:1903546]; regulation of gene expression [GO:0010468]; retina vasculature development in camera-type eye [GO:0061298]; visual perception [GO:0007601] photoreceptor outer segment membrane [GO:0042622]; plasma membrane [GO:0005886] protein homodimerization activity [GO:0042803] 0.6692 0.39393 ASLNAALYPPWR 0 0 11.9287 0 0 0 11.8717 0 0 0 0 0 0 0 0 12.25 0 0 10.2065 0 0 0 0 0 0 0 0 Q03405 UPAR_HUMAN Urokinase plasminogen activator surface receptor (U-PAR) (uPAR) (Monocyte activation antigen Mo3) (CD antigen CD87) PLAUR MO3 UPAR Homo sapiens (Human) blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; regulation of cell adhesion [GO:0030155]; regulation of fibrinolysis [GO:0051917]; regulation of plasminogen activation [GO:0010755]; regulation of proteolysis [GO:0030162]; signal transduction [GO:0007165]; urokinase plasminogen activator signaling pathway [GO:0038195] cell projection [GO:0042995]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extrinsic component of membrane [GO:0019898]; focal adhesion [GO:0005925]; membrane [GO:0016020]; plasma membrane [GO:0005886]; protein complex involved in cell-matrix adhesion [GO:0098637]; serine-type endopeptidase complex [GO:1905370]; specific granule membrane [GO:0035579] enzyme binding [GO:0019899]; protein domain specific binding [GO:0019904]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; urokinase plasminogen activator receptor activity [GO:0030377] 0.86987 0.051513 LWEEGEELELVEK 0 0 0 0 9.19508 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q03426 KIME_HUMAN Mevalonate kinase (MK) (EC 2.7.1.36) MVK Homo sapiens (Human) "cholesterol biosynthetic process [GO:0006695]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]; isoprenoid biosynthetic process [GO:0008299]; negative regulation of inflammatory response [GO:0050728]; phosphorylation [GO:0016310]" cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; peroxisome [GO:0005777] ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; mevalonate kinase activity [GO:0004496] 0.89625 -0.54169 EDLELINK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.1103 0 0 0 0 0 0 0 0 0 Q03468 ERCC6_HUMAN DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB) ERCC6 CSB Homo sapiens (Human) "base-excision repair [GO:0006284]; chromatin remodeling [GO:0006338]; DNA damage checkpoint signaling [GO:0000077]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; double-strand break repair via classical nonhomologous end joining [GO:0097680]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; multicellular organism growth [GO:0035264]; negative regulation of double-strand break repair via nonhomologous end joining [GO:2001033]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; neuron projection development [GO:0031175]; photoreceptor cell maintenance [GO:0045494]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; pyrimidine dimer repair [GO:0006290]; regulation of DNA-templated transcription elongation [GO:0032784]; regulation of transcription elongation by RNA polymerase II [GO:0034243]; response to gamma radiation [GO:0010332]; response to oxidative stress [GO:0006979]; response to superoxide [GO:0000303]; response to toxic substance [GO:0009636]; response to UV-B [GO:0010224]; response to X-ray [GO:0010165]; single strand break repair [GO:0000012]; transcription by RNA polymerase II [GO:0006366]; transcription elongation by RNA polymerase I [GO:0006362]; transcription-coupled nucleotide-excision repair [GO:0006283]" B-WICH complex [GO:0110016]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of DNA damage [GO:0090734]; transcription elongation factor complex [GO:0008023] "ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent activity, acting on DNA [GO:0008094]; ATP-dependent chromatin remodeler activity [GO:0140658]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; helicase activity [GO:0004386]; protein tyrosine kinase activator activity [GO:0030296]; RNA polymerase binding [GO:0070063]" 0.87085 0.034572 ERAWRIGQK 0 0 0 0 0 0 8.77057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q03518 TAP1_HUMAN Antigen peptide transporter 1 (APT1) (EC 7.4.2.14) (ATP-binding cassette sub-family B member 2) (Peptide supply factor 1) (Peptide transporter PSF1) (PSF-1) (Peptide transporter TAP1) (Peptide transporter involved in antigen processing 1) (Really interesting new gene 4 protein) (RING4) TAP1 ABCB2 PSF1 RING4 Y3 Homo sapiens (Human) adaptive immune response [GO:0002250]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cytosol to endoplasmic reticulum transport [GO:0046967]; defense response [GO:0006952]; peptide transport [GO:0015833]; protein transport [GO:0015031]; transmembrane transport [GO:0055085] centriolar satellite [GO:0034451]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; phagocytic vesicle membrane [GO:0030670]; TAP complex [GO:0042825] ABC-type peptide antigen transporter activity [GO:0015433]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]; metal ion binding [GO:0046872]; MHC class I protein binding [GO:0042288]; MHC class Ib protein binding [GO:0023029]; peptide antigen binding [GO:0042605]; peptide transmembrane transporter activity [GO:1904680]; protein homodimerization activity [GO:0042803]; TAP1 binding [GO:0046978]; TAP2 binding [GO:0046979] 0.63204 0.40446 AVGSSEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.61486 0 0 0 0 0 0 0 0 0 Q03701 CEBPZ_HUMAN CCAAT/enhancer-binding protein zeta (CCAAT-box-binding transcription factor) (CBF) (CCAAT-binding factor) CEBPZ CBF2 Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944] CCAAT-binding factor complex [GO:0016602]; nucleus [GO:0005634] RNA binding [GO:0003723]; transcription coactivator activity [GO:0003713] 0.21759 0.89368 GVVSGEVER 0 0 0 0 0 0 0 0 0 0 0 0 10.4555 0 0 0 0 10.4272 0 0 0 0 0 0 0 0 0 Q03721 KCNC4_HUMAN Potassium voltage-gated channel subfamily C member 4 (KSHIIIC) (Voltage-gated potassium channel subunit Kv3.4) KCNC4 C1orf30 Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of monoatomic ion transmembrane transport [GO:0034765] axon [GO:0030424]; dendrite membrane [GO:0032590]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; synapse [GO:0045202]; voltage-gated potassium channel complex [GO:0008076] delayed rectifier potassium channel activity [GO:0005251]; potassium channel activity [GO:0005267]; voltage-gated potassium channel activity [GO:0005249] 0.92376 -1.0468 STTRDRNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.73938 0 0 0 0 0 0 0 0 0 0 0 Q03923 ZNF85_HUMAN Zinc finger protein 85 (Zinc finger protein HPF4) (Zinc finger protein HTF1) ZNF85 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.88368 -0.12333 IIHTGEKPYKCK 0 0 0 0 0 0 0 0 0 0 0 0 11.0934 9.73471 0 0 0 0 0 0 0 0 0 0 0 0 0 Q03924 ZN117_HUMAN Zinc finger protein 117 (Provirus-linked krueppel) (h-PLK) (Zinc finger protein HPF9) ZNF117 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; zinc ion binding [GO:0008270]" 0.96136 -2.5639 AFKQFSNLTDHK 0 0 0 0 11.5887 0 0 0 0 0 0 10.6194 0 0 0 0 0 12.8337 0 0 0 0 0 0 0 0 0 Q03936 ZNF92_HUMAN Zinc finger protein 92 (Zinc finger protein HTF12) ZNF92 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; zinc ion binding [GO:0008270]" 0.96111 -2.0561 AFSWSSAFTKHK 8.68776 0 0 0 0 0 0 0 0 0 10.2301 10.4413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q03938 ZNF90_HUMAN Zinc finger protein 90 (Zinc finger protein HTF9) ZNF90 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; zinc ion binding [GO:0008270]" 0.91264 -0.75523 GCESVDEGK 10.1281 10.0727 10.1017 10.5159 10.5832 10.4978 10.5135 10.5844 10.4623 0 0 0 10.3119 10.4116 10.3499 10.2137 9.66114 10.1797 0 0 0 0 0 9.69822 0 0 0 Q04323 UBXN1_HUMAN UBX domain-containing protein 1 (SAPK substrate protein 1) (UBA/UBX 33.3 kDa protein) UBXN1 SAKS1 Homo sapiens (Human) negative regulation of ERAD pathway [GO:1904293]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098] ATPase binding [GO:0051117]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; K6-linked polyubiquitin modification-dependent protein binding [GO:0071796]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome regulatory particle binding [GO:1904855]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625] 0.89829 -0.66898 EALERERQR 0 0 0 0 0 0 0 0 0 0 15.0491 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q04446 GLGB_HUMAN "1,4-alpha-glucan-branching enzyme (EC 2.4.1.18) (Brancher enzyme) (Glycogen-branching enzyme)" GBE1 Homo sapiens (Human) generation of precursor metabolites and energy [GO:0006091]; glycogen biosynthetic process [GO:0005978]; glycogen metabolic process [GO:0005977]; negative regulation of neuron apoptotic process [GO:0043524] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062] "1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; carbohydrate binding [GO:0030246]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]" 0.92187 -1.1226 GNNESYHYAR 0 0 0 0 0 0 0 0 0 0 0 9.81925 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q04637 IF4G1_HUMAN Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220) EIF4G1 EIF4F EIF4G EIF4GI Homo sapiens (Human) behavioral fear response [GO:0001662]; cap-dependent translational initiation [GO:0002191]; cellular response to nutrient levels [GO:0031669]; energy homeostasis [GO:0097009]; lung development [GO:0030324]; macromolecule biosynthetic process [GO:0009059]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of autophagy [GO:0010507]; negative regulation of neuron death [GO:1901215]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; neuron differentiation [GO:0030182]; positive regulation of cell death [GO:0010942]; positive regulation of cell growth [GO:0030307]; positive regulation of eukaryotic translation initiation factor 4F complex assembly [GO:1905537]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of mRNA cap binding [GO:1905612]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of translation in response to endoplasmic reticulum stress [GO:0036493]; regulation of cellular response to stress [GO:0080135]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of polysome binding [GO:1905696]; regulation of presynapse assembly [GO:1905606]; regulation of translational initiation [GO:0006446]; response to ethanol [GO:0045471]; translation [GO:0006412]; translational initiation [GO:0006413] cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; eukaryotic translation initiation factor 4F complex [GO:0016281]; membrane [GO:0016020]; nucleus [GO:0005634]; polysome [GO:0005844]; postsynapse [GO:0098794] "ATP binding [GO:0005524]; eukaryotic initiation factor 4E binding [GO:0008190]; identical protein binding [GO:0042802]; molecular adaptor activity [GO:0060090]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; translation factor activity, RNA binding [GO:0008135]; translation initiation factor activity [GO:0003743]; translation initiation factor binding [GO:0031369]" 0.88891 -0.42474 ALPSEELNR 0 12.1982 0 0 0 0 9.29692 9.22251 0 0 0 0 0 0 0 10.6336 0 0 0 0 0 0 0 0 0 0 9.17597 Q04656 ATP7A_HUMAN Copper-transporting ATPase 1 (EC 7.2.2.8) (Copper pump 1) (Menkes disease-associated protein) ATP7A MC1 MNK Homo sapiens (Human) blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion homeostasis [GO:0055070]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; intracellular copper ion homeostasis [GO:0006878]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of response to wounding [GO:1903036]; positive regulation of tyrosinase activity [GO:0032773]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568] apical plasma membrane [GO:0016324]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; dendrite [GO:0030425]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; melanosome membrane [GO:0033162]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; secretory granule [GO:0030141]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588]; trans-Golgi network transport vesicle [GO:0030140] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper-dependent protein binding [GO:0032767]; cuprous ion binding [GO:1903136]; P-type divalent copper transporter activity [GO:0043682]; P-type monovalent copper transporter activity [GO:0140581]; protein-folding chaperone binding [GO:0051087]; small GTPase binding [GO:0031267]; superoxide dismutase copper chaperone activity [GO:0016532] 0.96728 -2.8073 APIQQFADK 0 0 9.53852 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.50418 0 0 0 0 0 0 0 Q04695 K1C17_HUMAN "Keratin, type I cytoskeletal 17 (39.1) (Cytokeratin-17) (CK-17) (Keratin-17) (K17)" KRT17 Homo sapiens (Human) epithelial cell differentiation [GO:0030855]; hair follicle morphogenesis [GO:0031069]; intermediate filament organization [GO:0045109]; keratinization [GO:0031424]; positive regulation of cell growth [GO:0030307]; positive regulation of hair follicle development [GO:0051798]; positive regulation of translation [GO:0045727] cornified envelope [GO:0001533]; cytosol [GO:0005829]; intermediate filament cytoskeleton [GO:0045111]; keratin filament [GO:0045095] structural molecule activity [GO:0005198] 0 22.784 ALEEANTELEVK 11.9933 11.9545 11.676 0 0 0 10.4737 10.3233 10.6033 10.244 10.2203 10.2372 0 0 0 9.24058 0 8.90228 0 0 0 0 0 0 0 0 0 Q04721 NOTC2_HUMAN Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)] NOTCH2 Homo sapiens (Human) activation of protein kinase B activity [GO:0032148]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; atrioventricular node development [GO:0003162]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cellular response to tumor cell [GO:0071228]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hemopoiesis [GO:0030097]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intracellular signal transduction [GO:0035556]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of osteoclast development [GO:2001204]; wound healing [GO:0042060] cell surface [GO:0009986]; cilium [GO:0005929]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] calcium ion binding [GO:0005509]; enzyme binding [GO:0019899]; NF-kappaB binding [GO:0051059]; signaling receptor activity [GO:0038023] 0.96339 -2.1392 IKRDSQGELMVYPYYGEK 9.56016 9.33858 9.17138 0 0 0 10.7428 0 0 9.05612 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q04724 TLE1_HUMAN Transducin-like enhancer protein 1 (E(Sp1) homolog) (Enhancer of split groucho-like protein 1) (ESG1) TLE1 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; negative regulation of anoikis [GO:2000811]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of gene expression [GO:0010628]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055] beta-catenin-TCF complex [GO:1990907]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] DNA-binding transcription factor binding [GO:0140297]; identical protein binding [GO:0042802]; transcription corepressor activity [GO:0003714] 0.76849 0.26876 SPMVGFDPPPHMR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.3938 9.56624 0 0 0 0 Q04726 TLE3_HUMAN Transducin-like enhancer protein 3 (Enhancer of split groucho-like protein 3) (ESG3) TLE3 KIAA1547 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cold-induced thermogenesis [GO:0120163]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055] beta-catenin-TCF complex [GO:1990907]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] transcription corepressor activity [GO:0003714] 0.95446 -1.5124 VEYDKLANEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.76636 0 0 10.566 0 0 0 Q04727 TLE4_HUMAN Transducin-like enhancer protein 4 (Grg-4) (Groucho-related protein 4) TLE4 GRG4 KIAA1261 Homo sapiens (Human) cellular response to leukemia inhibitory factor [GO:1990830]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Wnt signaling pathway [GO:0016055] beta-catenin-TCF complex [GO:1990907]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] chromatin binding [GO:0003682]; DNA-binding transcription factor binding [GO:0140297]; transcription corepressor activity [GO:0003714] 0.88485 -0.29547 DLSKMYPQTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.65937 0 0 0 0 0 0 9.56946 0 0 0 0 Q04741 EMX1_HUMAN Homeobox protein EMX1 (Empty spiracles homolog 1) (Empty spiracles-like protein 1) EMX1 Homo sapiens (Human) brain development [GO:0007420]; brain morphogenesis [GO:0048854]; central nervous system development [GO:0007417]; cerebral cortex neuron differentiation [GO:0021895]; cerebral cortex regionalization [GO:0021796]; homeostasis of number of cells [GO:0048872]; in utero embryonic development [GO:0001701]; neuroepithelial cell differentiation [GO:0060563]; neuron differentiation [GO:0030182]; neuron projection extension [GO:1990138]; post-embryonic development [GO:0009791]; radial glial cell differentiation [GO:0060019]; regulation of oligodendrocyte progenitor proliferation [GO:0070445]; response to xenobiotic stimulus [GO:0009410] chromatin [GO:0000785]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.47822 0.62477 LEEEGPESEQKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2088 0 0 0 0 0 0 0 0 0 0 Q04743 EMX2_HUMAN Homeobox protein EMX2 (Empty spiracles homolog 2) (Empty spiracles-like protein 2) EMX2 Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; brain development [GO:0007420]; cell proliferation in forebrain [GO:0021846]; central nervous system development [GO:0007417]; cerebral cortex regionalization [GO:0021796]; dentate gyrus development [GO:0021542]; forebrain cell migration [GO:0021885]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; response to xenobiotic stimulus [GO:0009410]; ureter morphogenesis [GO:0072197] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.8844 -0.12754 DPSTFYPWLIHRYRYLGHR 0 0 0 0 0 0 0 0 0 0 0 0 11.5891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q04759 KPCT_HUMAN Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta) PRKCQ PRKCT Homo sapiens (Human) "axon guidance [GO:0007411]; CD4-positive, alpha-beta T cell proliferation [GO:0035739]; cell chemotaxis [GO:0060326]; Fc-epsilon receptor signaling pathway [GO:0038095]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of T cell apoptotic process [GO:0070233]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell activation [GO:0050870]; positive regulation of T-helper 17 type immune response [GO:2000318]; positive regulation of T-helper 2 cell activation [GO:2000570]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein phosphorylation [GO:0006468]; regulation of cell growth [GO:0001558]; regulation of DNA-templated transcription [GO:0006355]; regulation of platelet aggregation [GO:0090330]" aggresome [GO:0016235]; centriolar satellite [GO:0034451]; cytosol [GO:0005829]; immunological synapse [GO:0001772]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; calcium-dependent protein kinase C activity [GO:0004698]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein kinase C activity [GO:0004697]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.95437 -1.5239 VANLCGINQK 0 0 0 9.01519 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q04760 LGUL_HUMAN Lactoylglutathione lyase (EC 4.4.1.5) (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde mutase) (Methylglyoxalase) (S-D-lactoylglutathione methylglyoxal lyase) GLO1 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; glutathione metabolic process [GO:0006749]; methylglyoxal metabolic process [GO:0009438]; negative regulation of apoptotic process [GO:0043066]; osteoclast differentiation [GO:0030316]; regulation of transcription by RNA polymerase II [GO:0006357] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] lactoylglutathione lyase activity [GO:0004462]; zinc ion binding [GO:0008270] 0.86506 0.084485 FSLYFLAYEDKNDIPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4499 9.66461 0 0 0 0 0 Q04828 AK1C1_HUMAN Aldo-keto reductase family 1 member C1 (EC 1.1.1.-) (EC 1.1.1.112) (EC 1.1.1.209) (EC 1.1.1.210) (EC 1.1.1.357) (EC 1.1.1.51) (EC 1.1.1.53) (EC 1.1.1.62) (EC 1.3.1.20) (20-alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (EC 1.1.1.149) (Chlordecone reductase homolog HAKRC) (Dihydrodiol dehydrogenase 1) (DD1) (High-affinity hepatic bile acid-binding protein) (HBAB) AKR1C1 DDH DDH1 Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; bile acid metabolic process [GO:0008206]; cellular response to jasmonic acid stimulus [GO:0071395]; cholesterol homeostasis [GO:0042632]; daunorubicin metabolic process [GO:0044597]; digestion [GO:0007586]; doxorubicin metabolic process [GO:0044598]; epithelial cell differentiation [GO:0030855]; intestinal cholesterol absorption [GO:0030299]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; response to organophosphorus [GO:0046683]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; xenobiotic metabolic process [GO:0006805] cytosol [GO:0005829]; extracellular exosome [GO:0070062] "17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity [GO:0047006]; 17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; 3beta-hydroxy-5beta-steroid dehydrogenase activity [GO:0033703]; 5alpha-androstane-3beta,17beta-diol dehydrogenase activity [GO:0047024]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androstan-3-alpha,17-beta-diol dehydrogenase activity [GO:0047044]; androsterone dehydrogenase (B-specific) activity [GO:0047042]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; dihydrotestosterone 17-beta-dehydrogenase activity [GO:0035410]; estradiol 17-beta-dehydrogenase [NAD(P)] activity [GO:0004303]; indanol dehydrogenase activity [GO:0047718]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0033764]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]; testosterone dehydrogenase [NAD(P)] activity [GO:0030283]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]" 0 16.552 AIDGLNR 9.00619 9.07261 0 0 0 0 11.3313 11.5765 11.3004 11.4054 10.7911 11.6299 12.1982 12.7016 12.6225 13.2925 13.0797 12.5983 0 0 0 0 10.4756 8.66042 0 0 0 Q04837 SSBP_HUMAN "Single-stranded DNA-binding protein, mitochondrial (Mt-SSB) (MtSSB) (PWP1-interacting protein 17)" SSBP1 SSBP Homo sapiens (Human) DNA unwinding involved in DNA replication [GO:0006268]; mitochondrial DNA replication [GO:0006264]; mitochondrion morphogenesis [GO:0070584]; positive regulation of DNA helicase activity [GO:1905776]; positive regulation of helicase activity [GO:0051096]; positive regulation of mitochondrial DNA replication [GO:0090297]; protein homotetramerization [GO:0051289] extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; nucleus [GO:0005634] chromatin binding [GO:0003682]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697] 0.21536 0.90169 DVAYQYVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.15008 0 0 Q04844 ACHE_HUMAN Acetylcholine receptor subunit epsilon CHRNE ACHRE Homo sapiens (Human) "acetylcholine receptor signaling pathway [GO:0095500]; chemical synaptic transmission [GO:0007268]; monoatomic ion transmembrane transport [GO:0034220]; muscle contraction [GO:0006936]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271]" acetylcholine-gated channel complex [GO:0005892]; neuromuscular junction [GO:0031594]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202] acetylcholine receptor activity [GO:0015464]; acetylcholine-gated monoatomic cation-selective channel activity [GO:0022848]; monoatomic cation transmembrane transporter activity [GO:0008324]; transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315] 0.95454 -1.519 GVGKNEELR 0 0 0 0 0 0 0 0 0 0 8.89636 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q04864 REL_HUMAN Proto-oncogene c-Rel REL Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-beta production [GO:0032688]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; response to cytokine [GO:0034097] chromatin [GO:0000785]; cytosol [GO:0005829]; NF-kappaB complex [GO:0071159]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.39516 0.70793 AGINPFNVPEK 0 0 0 0 0 8.67292 0 0 0 0 0 0 0 10.0508 0 0 0 0 0 0 0 9.5815 0 0 0 0 0 Q04912 RON_HUMAN Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain] MST1R PTK8 RON Homo sapiens (Human) cell migration [GO:0016477]; defense response [GO:0006952]; innate immune response [GO:0045087]; nervous system development [GO:0007399]; phagocytosis [GO:0006909]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; protein phosphorylation [GO:0006468]; response to virus [GO:0009615]; signal transduction [GO:0007165]; single fertilization [GO:0007338]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] cell surface [GO:0009986]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; stress fiber [GO:0001725]; vacuole [GO:0005773] ATP binding [GO:0005524]; enzyme binding [GO:0019899]; macrophage colony-stimulating factor receptor activity [GO:0005011]; transmembrane receptor protein tyrosine kinase activity [GO:0004714] 0.7717 0.268 ELVLDCR 0 0 0 0 0 8.4477 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q04941 PLP2_HUMAN Proteolipid protein 2 (Differentiation-dependent protein A4) (Intestinal membrane A4 protein) PLP2 A4 Homo sapiens (Human) chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; monoatomic ion transport [GO:0006811] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886] chemokine binding [GO:0019956]; monoatomic ion transmembrane transporter activity [GO:0015075] 0.31283 0.79282 HTAAPTDPADGPV 0 0 0 0 0 0 0 0 0 0 10.5578 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q05048 CSTF1_HUMAN Cleavage stimulation factor subunit 1 (CF-1 50 kDa subunit) (Cleavage stimulation factor 50 kDa subunit) (CSTF 50 kDa subunit) (CstF-50) CSTF1 Homo sapiens (Human) mRNA 3'-end processing [GO:0031124] mRNA cleavage stimulating factor complex [GO:0005848]; nucleoplasm [GO:0005654] RNA binding [GO:0003723] 0.89015 -0.48709 AFKYIQEAEMLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8553 10.3419 0 0 0 0 0 0 0 0 0 0 Q05084 ICA69_HUMAN Islet cell autoantigen 1 (69 kDa islet cell autoantigen) (ICA69) (Islet cell autoantigen p69) (ICAp69) (p69) ICA1 Homo sapiens (Human) neurotransmitter transport [GO:0006836]; regulation of transport [GO:0051049] cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; secretory granule membrane [GO:0030667]; synaptic vesicle membrane [GO:0030672] membrane curvature sensor activity [GO:0140090]; protein domain specific binding [GO:0019904] 0.96726 -2.8496 KESSSFKTEDGK 16.841 0 0 9.89019 9.41865 8.60047 0 11.5112 10.1158 0 0 0 0 0 0 0 0 0 0 0 0 12.9294 0 0 0 0 0 Q05086 UBE3A_HUMAN Ubiquitin-protein ligase E3A (EC 2.3.2.26) (E6AP ubiquitin-protein ligase) (HECT-type ubiquitin transferase E3A) (Human papillomavirus E6-associated protein) (Oncogenic protein-associated protein E6-AP) (Renal carcinoma antigen NY-REN-54) UBE3A E6AP EPVE6AP HPVE6A Homo sapiens (Human) androgen receptor signaling pathway [GO:0030521]; brain development [GO:0007420]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; locomotory exploration behavior [GO:0035641]; modulation of chemical synaptic transmission [GO:0050804]; motor learning [GO:0061743]; negative regulation of dendritic spine morphogenesis [GO:0061002]; ovarian follicle development [GO:0001541]; positive regulation of Golgi lumen acidification [GO:1905528]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; progesterone receptor signaling pathway [GO:0050847]; prostate gland growth [GO:0060736]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; proteolysis [GO:0006508]; regulation of circadian rhythm [GO:0042752]; regulation of ubiquitin-dependent protein catabolic process [GO:2000058]; response to cocaine [GO:0042220]; response to hydrogen peroxide [GO:0042542]; response to progesterone [GO:0032570]; rhythmic process [GO:0048511]; sperm entry [GO:0035037]; ubiquitin-dependent protein catabolic process [GO:0006511] cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; nucleus [GO:0005634]; proteasome complex [GO:0000502] metal ion binding [GO:0046872]; transcription coactivator activity [GO:0003713]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.93372 -1.2903 RAAAKHLIER 0 13.7161 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q05193 DYN1_HUMAN Dynamin-1 (EC 3.6.5.5) DNM1 DNM Homo sapiens (Human) endocytosis [GO:0006897]; endosome organization [GO:0007032]; modulation of chemical synaptic transmission [GO:0050804]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle endocytosis [GO:0048488]; toxin transport [GO:1901998] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; membrane coat [GO:0030117]; microtubule [GO:0005874]; photoreceptor inner segment [GO:0001917]; photoreceptor ribbon synapse [GO:0098684]; plasma membrane [GO:0005886]; presynaptic endocytic zone membrane [GO:0098835] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723] 0.96388 -2.1096 EYWFVLTAENLSWYKDDEEK 0 0 0 0 0 0 0 9.07601 9.35821 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q05215 EGR4_HUMAN Early growth response protein 4 (EGR-4) (AT133) EGR4 Homo sapiens (Human) positive regulation of cell population proliferation [GO:0008284]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleoplasm [GO:0005654] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.876 -0.0085619 APHSRRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.3077 0 10.2929 0 0 0 0 Q05397 FAK1_HUMAN Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK) PTK2 FAK FAK1 Homo sapiens (Human) angiogenesis [GO:0001525]; axon guidance [GO:0007411]; cell migration [GO:0016477]; cell motility [GO:0048870]; detection of muscle stretch [GO:0035995]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; growth hormone receptor signaling pathway [GO:0060396]; heart morphogenesis [GO:0003007]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion [GO:0022408]; netrin-activated signaling pathway [GO:0038007]; peptidyl-tyrosine phosphorylation [GO:0018108]; placenta development [GO:0001890]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of macrophage proliferation [GO:0120041]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of wound healing [GO:0090303]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of endothelial cell migration [GO:0010594]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of GTPase activity [GO:0043087]; regulation of osteoblast differentiation [GO:0045667]; regulation of protein phosphorylation [GO:0001932]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; signal complex assembly [GO:0007172]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] cell cortex [GO:0005938]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; stress fiber [GO:0001725] actin binding [GO:0003779]; ATP binding [GO:0005524]; integrin binding [GO:0005178]; JUN kinase binding [GO:0008432]; molecular function activator activity [GO:0140677]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; protein tyrosine phosphatase activity [GO:0004725]; SH2 domain binding [GO:0042169] 0.9694 -4.7271 EERFLKPDVR 11.6999 11.98 11.8851 10.2635 10.213 10.2671 11.4451 11.3481 11.4737 13.6495 13.3191 13.2525 8.89482 0 9.69293 0 0 0 0 0 0 0 0 0 0 0 0 Q05481 ZNF91_HUMAN Zinc finger protein 91 (Zinc finger protein HPF7) (Zinc finger protein HTF10) ZNF91 Homo sapiens (Human) retrotransposon silencing [GO:0010526] nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; zinc ion binding [GO:0008270]" 0.96875 -5.7975 CEECGKAFSHSSALAKHK 0 0 0 0 0 0 9.25158 9.4684 0 0 0 0 9.27557 0 0 0 0 0 0 0 0 0 10.3289 0 8.88536 0 0 Q05513 KPCZ_HUMAN Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta) PRKCZ PKC2 Homo sapiens (Human) activation of phospholipase D activity [GO:0031584]; activation of protein kinase B activity [GO:0032148]; cell migration [GO:0016477]; cell surface receptor signaling pathway [GO:0007166]; cellular response to insulin stimulus [GO:0032869]; establishment of cell polarity [GO:0030010]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of apoptotic process [GO:0043066]; negative regulation of hydrolase activity [GO:0051346]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of protein-containing complex assembly [GO:0031333]; neuron projection extension [GO:1990138]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-5 production [GO:0032754]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein transport [GO:0051222]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; protein kinase C signaling [GO:0070528]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; signal transduction [GO:0007165]; vesicle transport along microtubule [GO:0047496] apical cortex [GO:0045179]; apical plasma membrane [GO:0016324]; axon hillock [GO:0043203]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cell leading edge [GO:0031252]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule organizing center [GO:0005815]; myelin sheath abaxonal region [GO:0035748]; nuclear envelope [GO:0005635]; nuclear matrix [GO:0016363]; PAR polarity complex [GO:0120157]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; Schaffer collateral - CA1 synapse [GO:0098685]; stress fiber [GO:0001725]; tight junction [GO:0070160]; vesicle [GO:0031982] 14-3-3 protein binding [GO:0071889]; ATP binding [GO:0005524]; calcium-dependent protein kinase C activity [GO:0004698]; insulin receptor substrate binding [GO:0043560]; metal ion binding [GO:0046872]; phospholipase binding [GO:0043274]; potassium channel regulator activity [GO:0015459]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein kinase C activity [GO:0004697]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein-containing complex binding [GO:0044877] 0.96929 -3.5587 LYRANGHLFQAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.24781 0 0 9.81546 0 0 0 0 0 0 0 Q05516 ZBT16_HUMAN Zinc finger and BTB domain-containing protein 16 (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145) (Zinc finger protein PLZF) ZBTB16 PLZF ZNF145 Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; cartilage development [GO:0051216]; cell population proliferation [GO:0008283]; central nervous system development [GO:0007417]; embryonic digit morphogenesis [GO:0042733]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic pattern specification [GO:0009880]; forelimb morphogenesis [GO:0035136]; hemopoiesis [GO:0030097]; male germ-line stem cell asymmetric division [GO:0048133]; mesonephros development [GO:0001823]; myeloid cell differentiation [GO:0030099]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification involved in bone maturation [GO:0043931]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cartilage development [GO:0061036]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of NK T cell differentiation [GO:0051138]; positive regulation of ossification [GO:0045778]; protein localization to nucleus [GO:0034504]; protein ubiquitination [GO:0016567]; regulation of transcription by RNA polymerase II [GO:0006357] cytosol [GO:0005829]; male germ cell nucleus [GO:0001673]; nuclear body [GO:0016604]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; transcription repressor complex [GO:0017053] "DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; transcription corepressor binding [GO:0001222]; type 2 angiotensin receptor binding [GO:0031703]" 0.51194 0.60157 DYSAMIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.93177 0 0 0 0 0 0 0 0 0 0 Q05586 NMDZ1_HUMAN "Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1)" GRIN1 NMDAR1 Homo sapiens (Human) "brain development [GO:0007420]; calcium ion homeostasis [GO:0055074]; calcium ion transmembrane import into cytosol [GO:0097553]; chemical synaptic transmission [GO:0007268]; excitatory chemical synaptic transmission [GO:0098976]; excitatory postsynaptic potential [GO:0060079]; ionotropic glutamate receptor signaling pathway [GO:0035235]; monoatomic cation transmembrane transport [GO:0098655]; monoatomic cation transport [GO:0006812]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; propylene metabolic process [GO:0018964]; protein heterotetramerization [GO:0051290]; regulation of membrane potential [GO:0042391]; regulation of monoatomic cation transmembrane transport [GO:1904062]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of synaptic plasticity [GO:0048167]; response to ethanol [GO:0045471]; response to glycine [GO:1905429]; visual learning [GO:0008542]" cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; excitatory synapse [GO:0060076]; neuron projection [GO:0043005]; NMDA selective glutamate receptor complex [GO:0017146]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic cleft [GO:0043083]; synaptic membrane [GO:0097060]; synaptic vesicle [GO:0008021]; terminal bouton [GO:0043195] amyloid-beta binding [GO:0001540]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; glutamate binding [GO:0016595]; glutamate-gated calcium ion channel activity [GO:0022849]; glycine binding [GO:0016594]; ligand-gated monoatomic ion channel activity [GO:0015276]; neurotransmitter binding [GO:0042165]; NMDA glutamate receptor activity [GO:0004972]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023] 0.91938 -0.90036 GALQNQK 13.4047 13.4365 13.1121 10.3592 10.6847 11.8523 12.844 12.8889 12.9186 0 0 0 9.90745 10.2888 10.3968 0 10.1902 10.0107 0 10.7332 0 0 0 0 0 0 0 Q05655 KPCD_HUMAN Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) (EC 2.7.10.2) (nPKC-delta) [Cleaved into: Protein kinase C delta type regulatory subunit; Protein kinase C delta type catalytic subunit (Sphingosine-dependent protein kinase-1) (SDK1)] PRKCD PKCD Homo sapiens (Human) activation of protein kinase activity [GO:0032147]; apoptotic process [GO:0006915]; B cell proliferation [GO:0042100]; cell chemotaxis [GO:0060326]; cell cycle [GO:0007049]; cellular response to angiotensin [GO:1904385]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hydroperoxide [GO:0071447]; cellular response to UV [GO:0034644]; cellular senescence [GO:0090398]; defense response to bacterium [GO:0042742]; DNA damage response [GO:0006974]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immunoglobulin mediated immune response [GO:0016064]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of filopodium assembly [GO:0051490]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of inflammatory response [GO:0050728]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of protein binding [GO:0032091]; neutrophil activation [GO:0042119]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of endodeoxyribonuclease activity [GO:0032079]; positive regulation of glucosylceramide catabolic process [GO:2000753]; positive regulation of phospholipid scramblase activity [GO:1900163]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of sphingomyelin catabolic process [GO:2000755]; positive regulation of superoxide anion generation [GO:0032930]; post-translational protein modification [GO:0043687]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of ceramide biosynthetic process [GO:2000303]; regulation of mRNA stability [GO:0043488]; regulation of signaling receptor activity [GO:0010469]; signal transduction [GO:0007165]; termination of signal transduction [GO:0023021] azurophil granule lumen [GO:0035578]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endolysosome [GO:0036019]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; calcium-dependent protein kinase C activity [GO:0004698]; calcium-independent protein kinase C activity [GO:0004699]; enzyme activator activity [GO:0008047]; enzyme binding [GO:0019899]; insulin receptor substrate binding [GO:0043560]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein kinase C activity [GO:0004697]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.92778 -1.224 IADFGMCKENIFGESR 0 0 0 0 0 0 8.97516 0 0 0 8.82715 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q05682 CALD1_HUMAN Caldesmon (CDM) CALD1 CAD CDM Homo sapiens (Human) actin filament bundle assembly [GO:0051017]; angiogenesis [GO:0001525]; muscle contraction [GO:0006936] actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; myofibril [GO:0030016]; plasma membrane [GO:0005886] actin binding [GO:0003779]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; myosin binding [GO:0017022]; tropomyosin binding [GO:0005523] 0.88921 -0.44296 LQEDKPTFK 0 0 0 0 0 0 0 0 9.05243 9.56207 10.1025 9.98726 9.40423 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9077 Q05707 COEA1_HUMAN Collagen alpha-1(XIV) chain (Undulin) COL14A1 UND Homo sapiens (Human) cell-cell adhesion [GO:0098609]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198] collagen trimer [GO:0005581]; collagen type XIV trimer [GO:0005596]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interstitial matrix [GO:0005614] collagen binding [GO:0005518]; extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020]; protein-macromolecule adaptor activity [GO:0030674]; RNA binding [GO:0003723] 0.9203 -0.91746 LMWIPVYGGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.38072 0 Q05823 RN5A_HUMAN 2-5A-dependent ribonuclease (2-5A-dependent RNase) (EC 3.1.26.-) (Ribonuclease 4) (Ribonuclease L) (RNase L) RNASEL RNS4 Homo sapiens (Human) defense response to virus [GO:0051607]; fat cell differentiation [GO:0045444]; mRNA processing [GO:0006397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of glucose import [GO:0046326]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of mRNA stability [GO:0043488]; RNA processing [GO:0006396]; rRNA processing [GO:0006364] cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nuclear matrix [GO:0016363] ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; ribonucleoprotein complex binding [GO:0043021]; RNA binding [GO:0003723]; RNA endonuclease activity [GO:0004521]; RNA nuclease activity [GO:0004540]; rRNA binding [GO:0019843] 0.95141 -1.4307 AAVEDNHLLIK 0 15.0377 14.8156 10.9927 9.86762 11.1899 0 0 14.749 0 15.3902 15.0887 12.6888 0 0 0 9.13443 0 0 0 11.8476 12.9294 11.5481 0 10.3067 0 0 Q05901 ACHB3_HUMAN Neuronal acetylcholine receptor subunit beta-3 CHRNB3 Homo sapiens (Human) "chemical synaptic transmission [GO:0007268]; membrane depolarization [GO:0051899]; monoatomic ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271]" acetylcholine-gated channel complex [GO:0005892]; dopaminergic synapse [GO:0098691]; membrane [GO:0016020]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynapse [GO:0098793]; synapse [GO:0045202] acetylcholine binding [GO:0042166]; acetylcholine-gated monoatomic cation-selective channel activity [GO:0022848]; channel activity [GO:0015267]; heterocyclic compound binding [GO:1901363]; transmembrane signaling receptor activity [GO:0004888] 0.92189 -1.0905 LLCMKDHVDR 0 0 0 0 0 0 10.712 0 0 0 0 0 0 0 0 0 0 0 0 9.6977 0 0 0 0 11.5292 0 0 Q05923 DUS2_HUMAN Dual specificity protein phosphatase 2 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase PAC-1) DUSP2 PAC1 Homo sapiens (Human) endoderm formation [GO:0001706]; negative regulation of MAPK cascade [GO:0043409]; protein dephosphorylation [GO:0006470] cytoplasm [GO:0005737]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] MAP kinase tyrosine phosphatase activity [GO:0033550]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; mitogen-activated protein kinase binding [GO:0051019]; myosin phosphatase activity [GO:0017018]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/threonine phosphatase activity [GO:0008330] 0.80946 0.23349 ELECAALGTLLR 0 0 0 0 0 0 0 0 0 9.21323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q05925 HME1_HUMAN Homeobox protein engrailed-1 (Homeobox protein en-1) (Hu-En-1) EN1 Homo sapiens (Human) adult locomotory behavior [GO:0008344]; anatomical structure morphogenesis [GO:0009653]; cerebellum development [GO:0021549]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral pattern formation [GO:0009953]; drinking behavior [GO:0042756]; embryonic brain development [GO:1990403]; embryonic forelimb morphogenesis [GO:0035115]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; motor learning [GO:0061743]; multicellular organism growth [GO:0035264]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; pigmentation [GO:0043473]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proximal/distal pattern formation [GO:0009954]; regulation of transcription by RNA polymerase II [GO:0006357]; response to cocaine [GO:0042220]; skeletal system development [GO:0001501]; social behavior [GO:0035176] chromatin [GO:0000785]; membrane [GO:0016020]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.65245 0.3957 GGAGGGGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.1047 0 0 0 0 0 0 0 Q05932 FOLC_HUMAN "Folylpolyglutamate synthase, mitochondrial (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolylpolyglutamate synthase) (Tetrahydrofolate synthase)" FPGS Homo sapiens (Human) animal organ regeneration [GO:0031100]; brain development [GO:0007420]; cell population proliferation [GO:0008283]; folic acid metabolic process [GO:0046655]; folic acid-containing compound metabolic process [GO:0006760]; glutamate metabolic process [GO:0006536]; liver development [GO:0001889]; nucleobase-containing compound metabolic process [GO:0006139]; one-carbon metabolic process [GO:0006730]; tetrahydrofolylpolyglutamate biosynthetic process [GO:0046901] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; tetrahydrofolylpolyglutamate synthase activity [GO:0004326] 0.78897 0.25095 AALFLAAASAR 0 0 14.1948 0 0 0 0 0 0 13.2945 0 0 0 0 0 0 0 0 0 0 0 8.36172 0 0 0 0 0 Q05996 ZP2_HUMAN Zona pellucida sperm-binding protein 2 (Zona pellucida glycoprotein 2) (Zp-2) (Zona pellucida protein A) [Cleaved into: Processed zona pellucida sperm-binding protein 2] ZP2 ZPA Homo sapiens (Human) binding of sperm to zona pellucida [GO:0007339]; prevention of polyspermy [GO:0060468] collagen-containing extracellular matrix [GO:0062023]; egg coat [GO:0035805]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886] acrosin binding [GO:0032190]; coreceptor activity [GO:0015026]; identical protein binding [GO:0042802]; structural constituent of egg coat [GO:0035804] 0.88487 -0.24265 VLNRDDPNIK 0 0 0 0 0 0 0 0 0 0 9.0278 0 0 0 0 0 0 9.62394 0 0 0 0 0 0 0 0 0 Q05BV3 EMAL5_HUMAN Echinoderm microtubule-associated protein-like 5 (EMAP-5) EML5 Homo sapiens (Human) cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; microtubule [GO:0005874] microtubule binding [GO:0008017] 0.82335 0.21595 DYVATGQVGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.97528 0 0 0 0 0 0 0 0 0 0 0 0 Q05D32 CTSL2_HUMAN CTD small phosphatase-like protein 2 (CTDSP-like 2) (EC 3.1.3.-) CTDSPL2 HSPC058 HSPC129 Homo sapiens (Human) negative regulation of BMP signaling pathway [GO:0030514]; positive regulation of protein export from nucleus [GO:0046827]; protein dephosphorylation [GO:0006470]; protein export from nucleus [GO:0006611] nucleoplasm [GO:0005654] phosphoprotein phosphatase activity [GO:0004721]; RNA polymerase II CTD heptapeptide repeat phosphatase activity [GO:0008420] 0.55895 0.51933 LEDNPSSGSPPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.35957 10.2454 0 0 0 Q05D60 DEUP1_HUMAN Deuterosome assembly protein 1 (Coiled-coil domain-containing protein 67) DEUP1 CCDC67 Homo sapiens (Human) cell projection organization [GO:0030030]; centriole replication [GO:0007099]; de novo centriole assembly involved in multi-ciliated epithelial cell differentiation [GO:0098535]; multi-ciliated epithelial cell differentiation [GO:1903251] centriole [GO:0005814]; cytoplasm [GO:0005737]; deuterosome [GO:0098536] identical protein binding [GO:0042802] 0.835 0.18787 LSHDCEPNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.27775 0 0 0 0 Q05DH4 FHI1A_HUMAN FHF complex subunit HOOK-interacting protein 1A (FHIP1A) (FTS- and Hook-interacting protein like) (FHIP-L) FHIP1A FAM160A1 Homo sapiens (Human) protein localization to perinuclear region of cytoplasm [GO:1905719] 0.9543 -1.5187 DPIQEASRTGSGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.87447 Q06124 PTN11_HUMAN Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase 2C) (PTP-2C) (SH-PTP2) (SHP-2) (Shp2) (SH-PTP3) PTPN11 PTP2C SHPTP2 Homo sapiens (Human) atrioventricular canal development [GO:0036302]; axonogenesis [GO:0007409]; Bergmann glial cell differentiation [GO:0060020]; brain development [GO:0007420]; cellular response to epidermal growth factor stimulus [GO:0071364]; cerebellar cortex formation [GO:0021697]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage checkpoint signaling [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB signaling pathway [GO:0038127]; face morphogenesis [GO:0060325]; fibroblast growth factor receptor signaling pathway [GO:0008543]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; hormone metabolic process [GO:0042445]; hormone-mediated signaling pathway [GO:0009755]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; intestinal epithelial cell migration [GO:0061582]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organism growth [GO:0035264]; multicellular organismal reproductive process [GO:0048609]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; negative regulation of type I interferon production [GO:0032480]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; peptidyl-tyrosine dephosphorylation [GO:0035335]; platelet formation [GO:0030220]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of ossification [GO:0045778]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of tumor necrosis factor production [GO:0032760]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of protein export from nucleus [GO:0046825]; regulation of protein-containing complex assembly [GO:0043254]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]; triglyceride metabolic process [GO:0006641] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; insulin receptor binding [GO:0005158]; molecular adaptor activity [GO:0060090]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; peptide hormone receptor binding [GO:0051428]; phosphoprotein phosphatase activity [GO:0004721]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor complex adaptor activity [GO:0030159] 0.90998 -0.74626 EKNGDVIELK 0 0 0 0 0 0 10.1677 0 0 0 10.2608 0 9.96078 0 0 0 0 0 0 0 0 0 0 0 0 9.79159 0 Q06187 BTK_HUMAN Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase) BTK AGMX1 ATK BPK Homo sapiens (Human) adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; B cell activation [GO:0042113]; B cell affinity maturation [GO:0002344]; B cell receptor signaling pathway [GO:0050853]; calcium-mediated signaling [GO:0019722]; cell maturation [GO:0048469]; cellular response to interleukin-7 [GO:0098761]; cellular response to molecule of fungal origin [GO:0071226]; cellular response to reactive oxygen species [GO:0034614]; eosinophil homeostasis [GO:1990959]; Fc-epsilon receptor signaling pathway [GO:0038095]; histamine secretion by mast cell [GO:0002553]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; mesoderm development [GO:0007498]; monocyte proliferation [GO:0061516]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil homeostasis [GO:0001780]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of interleukin-17A production [GO:0150153]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227]; positive regulation of phagocytosis [GO:0050766]; positive regulation of synoviocyte proliferation [GO:1901647]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type III hypersensitivity [GO:0001805]; protein phosphorylation [GO:0006468]; proteoglycan catabolic process [GO:0030167]; regulation of B cell apoptotic process [GO:0002902]; regulation of B cell cytokine production [GO:0002721]; response to lipopolysaccharide [GO:0032496]; T cell receptor signaling pathway [GO:0050852] cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; membrane raft [GO:0045121]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] "ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phospholipase activator activity [GO:0016004]; phospholipase binding [GO:0043274]; protein tyrosine kinase activity [GO:0004713]" 0.95176 -1.3838 YPVSQQNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.89075 0 0 0 0 0 0 Q06190 P2R3A_HUMAN Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha (PP2A subunit B isoform PR72/PR130) (PP2A subunit B isoform R3 isoform) (PP2A subunit B isoforms B''-PR72/PR130) (PP2A subunit B isoforms B72/B130) (Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B) PPP2R3A PPP2R3 Homo sapiens (Human) eye photoreceptor cell differentiation [GO:0001754]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of protein catabolic process [GO:0045732]; protein dephosphorylation [GO:0006470]; regulation of cell migration involved in somitogenic axis elongation [GO:0090249]; somatic muscle development [GO:0007525]; somite development [GO:0061053]; Wnt signaling pathway involved in somitogenesis [GO:0090244] protein phosphatase type 2A complex [GO:0000159] calcium ion binding [GO:0005509]; protein phosphatase regulator activity [GO:0019888]; protein-macromolecule adaptor activity [GO:0030674] 0.33672 0.77251 DIAGEAISFASGK 9.7252 0 9.48361 0 0 0 0 9.45658 9.44056 0 0 0 10.8533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q06210 GFPT1_HUMAN Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (EC 2.6.1.16) (D-fructose-6-phosphate amidotransferase 1) (Glutamine:fructose-6-phosphate amidotransferase 1) (GFAT 1) (GFAT1) (Hexosephosphate aminotransferase 1) GFPT1 GFAT GFPT Homo sapiens (Human) circadian regulation of gene expression [GO:0032922]; energy reserve metabolic process [GO:0006112]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047] cytosol [GO:0005829]; extracellular exosome [GO:0070062] carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360] 0.89847 -0.6165 EILETLIK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8633 0 0 0 0 0 0 0 0 0 8.76673 0 9.00983 0 Q06265 EXOS9_HUMAN Exosome complex component RRP45 (Autoantigen PM/Scl 1) (Exosome component 9) (P75 polymyositis-scleroderma overlap syndrome-associated autoantigen) (Polymyositis/scleroderma autoantigen 1) (Polymyositis/scleroderma autoantigen 75 kDa) (PM/Scl-75) EXOSC9 PMSCL1 Homo sapiens (Human) "exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; immune response [GO:0006955]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; positive regulation of cell growth [GO:0030307]; positive regulation of transcription by RNA polymerase II [GO:0045944]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; rRNA processing [GO:0006364]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476]" cytoplasm [GO:0005737]; cytoplasmic exosome (RNase complex) [GO:0000177]; cytosol [GO:0005829]; exosome (RNase complex) [GO:0000178]; extracellular exosome [GO:0070062]; nuclear chromosome [GO:0000228]; nuclear exosome (RNase complex) [GO:0000176]; nucleolar exosome (RNase complex) [GO:0101019]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 3'-5'-RNA exonuclease activity [GO:0000175]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; RNA binding [GO:0003723]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629] 0.87729 0.021488 FGFAESIANQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.0754 0 0 0 0 0 9.3441 0 Q06278 AOXA_HUMAN Aldehyde oxidase (EC 1.2.3.1) (Aldehyde oxidase 1) (Azaheterocycle hydroxylase) (EC 1.17.3.-) AOX1 AO Homo sapiens (Human) lipid metabolic process [GO:0006629]; xenobiotic metabolic process [GO:0006805] cytosol [GO:0005829]; extracellular exosome [GO:0070062] "2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde oxidase activity [GO:0004031]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; molybdopterin cofactor binding [GO:0043546]; NAD binding [GO:0051287]; protein homodimerization activity [GO:0042803]" 0.88967 -0.44648 HWNEQMLDIACR 0 0 0 0 0 8.67292 0 0 0 9.21213 0 12.8365 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q06323 PSME1_HUMAN Proteasome activator complex subunit 1 (11S regulator complex subunit alpha) (REG-alpha) (Activator of multicatalytic protease subunit 1) (Interferon gamma up-regulated I-5111 protein) (IGUP I-5111) (Proteasome activator 28 subunit alpha) (PA28a) (PA28alpha) PSME1 IFI5111 Homo sapiens (Human) antigen processing and presentation of exogenous antigen [GO:0019884]; positive regulation of endopeptidase activity [GO:0010950]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of proteasomal protein catabolic process [GO:0061136] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; proteasome activator complex [GO:0008537]; proteasome complex [GO:0000502] endopeptidase activator activity [GO:0061133] 0.96951 -3.0391 EKEKEER 0 0 0 0 0 0 0 0 0 8.52662 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q06418 TYRO3_HUMAN Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF) TYRO3 BYK DTK RSE SKY TIF Homo sapiens (Human) apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; forebrain cell migration [GO:0021885]; natural killer cell differentiation [GO:0001779]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of lymphocyte activation [GO:0051250]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; nervous system development [GO:0007399]; neuron apoptotic process [GO:0051402]; neuron cellular homeostasis [GO:0070050]; neuron migration [GO:0001764]; neuropeptide signaling pathway [GO:0007218]; ovulation cycle [GO:0042698]; phagocytosis [GO:0006909]; phosphatidylinositol 3-kinase signaling [GO:0014065]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; positive regulation of kinase activity [GO:0033674]; positive regulation of viral life cycle [GO:1903902]; protein autophosphorylation [GO:0046777]; protein kinase B signaling [GO:0043491]; secretion by cell [GO:0032940]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283]; substrate adhesion-dependent cell spreading [GO:0034446]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vagina development [GO:0060068] cell surface [GO:0009986]; endoplasmic reticulum membrane [GO:0005789]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] ATP binding [GO:0005524]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618] 0.94554 -1.3407 KIYSGDYYRQGCASK 0 0 0 0 11.5377 0 0 0 0 0 11.4213 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q06455 MTG8_HUMAN Protein CBFA2T1 (Cyclin-D-related protein) (Eight twenty one protein) (Protein ETO) (Protein MTG8) (Zinc finger MYND domain-containing protein 2) RUNX1T1 AML1T1 CBFA2T1 CDR ETO MTG8 ZMYND2 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of fat cell differentiation [GO:0045599] nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; DNA-binding transcription factor binding [GO:0140297]; metal ion binding [GO:0046872]; transcription corepressor activity [GO:0003714] 0.91541 -0.7704 KKGNFEYCQDR 0 0 0 0 0 0 0 0 0 0 8.38457 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q06546 GABPA_HUMAN GA-binding protein alpha chain (GABP subunit alpha) (Nuclear respiratory factor 2 subunit alpha) (Transcription factor E4TF1-60) GABPA E4TF1A Homo sapiens (Human) blastocyst formation [GO:0001825]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]" 0.93187 -1.2563 AAKVQRAPR 0 0 0 0 0 0 0 0 0 13.2923 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q06732 ZN33B_HUMAN Zinc finger protein 33B (Zinc finger protein 11B) (Zinc finger protein KOX2) ZNF33B KOX2 ZNF11B Homo sapiens (Human) nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.91375 -0.79811 HTGEKPYECNECGK 0 0 0 10.5364 10.4738 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q06787 FMR1_HUMAN Fragile X messenger ribonucleoprotein 1 (Fragile X messenger ribonucleoprotein) (FMRP) (Protein FMR-1) FMR1 Homo sapiens (Human) "cellular response to virus [GO:0098586]; DNA repair [GO:0006281]; glutamate receptor signaling pathway [GO:0007215]; modulation by host of viral RNA genome replication [GO:0044830]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; negative regulation of cytoplasmic translation [GO:2000766]; negative regulation of long-term synaptic depression [GO:1900453]; negative regulation of mRNA catabolic process [GO:1902373]; negative regulation of synaptic vesicle exocytosis [GO:2000301]; negative regulation of translation [GO:0017148]; negative regulation of translational initiation [GO:0045947]; negative regulation of voltage-gated calcium channel activity [GO:1901386]; nervous system development [GO:0007399]; non-membrane-bounded organelle assembly [GO:0140694]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular transport of viral material [GO:1901254]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; positive regulation of mRNA binding [GO:1902416]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of dendritic spine development [GO:0060998]; regulation of filopodium assembly [GO:0051489]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of mRNA stability [GO:0043488]; regulation of neuronal action potential [GO:0098908]; regulation of neurotransmitter secretion [GO:0046928]; RNA splicing [GO:0008380]; RNA-mediated gene silencing [GO:0031047]; stress granule assembly [GO:0034063]" "axon [GO:0030424]; axon terminus [GO:0043679]; Cajal body [GO:0015030]; cell projection [GO:0042995]; chromocenter [GO:0010369]; chromosome [GO:0005694]; chromosome, centromeric region [GO:0000775]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic filopodium [GO:1902737]; dendritic spine [GO:0043197]; dendritic spine neck [GO:0044326]; extrinsic component of plasma membrane [GO:0019897]; filopodium tip [GO:0032433]; glial cell projection [GO:0097386]; growth cone [GO:0030426]; growth cone filopodium [GO:1990812]; intracellular non-membrane-bounded organelle [GO:0043232]; membrane [GO:0016020]; messenger ribonucleoprotein complex [GO:1990124]; mRNA cap binding complex [GO:0005845]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; neuronal ribonucleoprotein granule [GO:0071598]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; polysome [GO:0005844]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynapse [GO:0098793]; presynaptic membrane [GO:0042734]; ribonucleoprotein complex [GO:1990904]; synapse [GO:0045202]" chromatin binding [GO:0003682]; DNA binding [GO:0003677]; dynein complex binding [GO:0070840]; G-quadruplex RNA binding [GO:0002151]; identical protein binding [GO:0042802]; methylated histone binding [GO:0035064]; microtubule binding [GO:0008017]; miRNA binding [GO:0035198]; molecular condensate scaffold activity [GO:0140693]; mRNA 3'-UTR binding [GO:0003730]; mRNA 5'-UTR binding [GO:0048027]; mRNA binding [GO:0003729]; N6-methyladenosine-containing RNA binding [GO:1990247]; poly(G) binding [GO:0034046]; poly(U) RNA binding [GO:0008266]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; ribosome binding [GO:0043022]; RNA binding [GO:0003723]; RNA stem-loop binding [GO:0035613]; RNA strand annealing activity [GO:0033592]; sequence-specific mRNA binding [GO:1990825]; signaling adaptor activity [GO:0035591]; siRNA binding [GO:0035197]; translation initiation factor binding [GO:0031369]; translation regulator activity [GO:0045182]; translation repressor activity [GO:0030371]; transmembrane transporter binding [GO:0044325] 0.95538 -1.5586 EAAHKDFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.1145 Q06828 FMOD_HUMAN Fibromodulin (FM) (Collagen-binding 59 kDa protein) (Keratan sulfate proteoglycan fibromodulin) (KSPG fibromodulin) FMOD FM SLRR2E Homo sapiens (Human) collagen fibril organization [GO:0030199]; transforming growth factor beta receptor complex assembly [GO:0007181] collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; lysosomal lumen [GO:0043202] 0.92164 -1.0914 SLRELHLDHNQISR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3504 0 0 0 0 0 0 0 0 0 9.38748 0 0 0 Q06830 PRDX1_HUMAN Peroxiredoxin-1 (EC 1.11.1.24) (Natural killer cell-enhancing factor A) (NKEF-A) (Proliferation-associated gene protein) (PAG) (Thioredoxin peroxidase 2) (Thioredoxin-dependent peroxide reductase 2) (Thioredoxin-dependent peroxiredoxin 1) PRDX1 PAGA PAGB TDPX2 Homo sapiens (Human) cell population proliferation [GO:0008283]; cell redox homeostasis [GO:0045454]; erythrocyte homeostasis [GO:0034101]; fibroblast proliferation [GO:0048144]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of stress-activated MAPK cascade [GO:0032872]; removal of superoxide radicals [GO:0019430]; response to oxidative stress [GO:0006979]; retina homeostasis [GO:0001895]; skeletal system development [GO:0001501] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; melanosome [GO:0042470]; nucleus [GO:0005634] cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; RNA binding [GO:0003723]; thioredoxin peroxidase activity [GO:0008379] 0 64.698 ADEGISFR 12.1605 12.1042 12.043 9.3215 10.2486 0 12.9532 12.8795 12.6005 14.0688 13.9992 11.5892 12.9659 13.0391 13.2881 14.0474 13.9404 13.7106 12.8961 13.2025 13.009 12.9574 13.3295 12.728 14.8103 14.7741 14.4444 Q06889 EGR3_HUMAN Early growth response protein 3 (EGR-3) (Zinc finger protein pilot) EGR3 PILOT Homo sapiens (Human) cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; circadian rhythm [GO:0007623]; endothelial cell chemotaxis [GO:0035767]; muscle organ development [GO:0007517]; negative regulation of apoptotic process [GO:0043066]; neuromuscular synaptic transmission [GO:0007274]; peripheral nervous system development [GO:0007422]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of T cell differentiation in thymus [GO:0033089]; regulation of gamma-delta T cell differentiation [GO:0045586]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; synapse [GO:0045202] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.86354 0.084132 IHTGHKPFQCRICMR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5468 0 Q07001 ACHD_HUMAN Acetylcholine receptor subunit delta CHRND ACHRD Homo sapiens (Human) acetylcholine receptor signaling pathway [GO:0095500]; chemical synaptic transmission [GO:0007268]; monoatomic ion transmembrane transport [GO:0034220]; muscle contraction [GO:0006936]; musculoskeletal movement [GO:0050881]; nervous system process [GO:0050877]; neuromuscular process [GO:0050905]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165]; skeletal muscle contraction [GO:0003009]; skeletal muscle tissue growth [GO:0048630] acetylcholine-gated channel complex [GO:0005892]; cytosol [GO:0005829]; neuromuscular junction [GO:0031594]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; postsynaptic specialization membrane [GO:0099634]; synapse [GO:0045202] acetylcholine binding [GO:0042166]; acetylcholine-gated monoatomic cation-selective channel activity [GO:0022848]; transmembrane signaling receptor activity [GO:0004888]; transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315] 0.86369 0.088395 DQNNYNEEKDSWNR 0 0 0 0 0 0 0 8.48997 0 0 0 9.51944 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q07002 CDK18_HUMAN Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) (PCTAIRE-motif protein kinase 3) (Serine/threonine-protein kinase PCTAIRE-3) CDK18 PCTAIRE3 PCTK3 Homo sapiens (Human) protein phosphorylation [GO:0006468]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083] cytoplasm [GO:0005737]; nucleus [GO:0005634] ATP binding [GO:0005524]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein serine kinase activity [GO:0106310] 0.78725 0.25821 FSLSVPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.7128 0 0 0 0 0 0 0 0 0 0 0 0 Q07020 RL18_HUMAN Large ribosomal subunit protein eL18 (60S ribosomal protein L18) RPL18 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; endoplasmic reticulum [GO:0005783]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; polysomal ribosome [GO:0042788]; rough endoplasmic reticulum [GO:0005791] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0 50.256 EVYRHFGK 9.94591 0 0 0 8.74819 0 10.4174 10.4522 10.4115 9.31547 0 9.05688 10.0425 10.3823 10.774 11.081 0 10.1473 10.0109 9.57281 9.94213 9.8588 10 9.82903 0 0 10.7993 Q07065 CKAP4_HUMAN Cytoskeleton-associated protein 4 (63-kDa cytoskeleton-linking membrane protein) (Climp-63) (p63) CKAP4 Homo sapiens (Human) azurophil granule membrane [GO:0035577]; cytoskeleton [GO:0005856]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; lamellar body [GO:0042599]; lipid droplet [GO:0005811]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; specific granule membrane [GO:0035579] RNA binding [GO:0003723] 0 50.601 ASVSQVEADLK 0 0 0 0 0 0 10.0336 8.41392 9.21825 10.5432 9.35443 10.969 10.0542 0 0 9.54429 11.6512 9.66796 13.3617 13.1182 12.7193 11.4556 12.3451 11.7805 14.4656 14.2296 13.8013 Q07075 AMPE_HUMAN Glutamyl aminopeptidase (EAP) (EC 3.4.11.7) (Aminopeptidase A) (AP-A) (Differentiation antigen gp160) (CD antigen CD249) ENPEP Homo sapiens (Human) angiogenesis [GO:0001525]; angiotensin maturation [GO:0002003]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cell-cell signaling [GO:0007267]; glomerulus development [GO:0032835]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081] apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; brush border [GO:0005903]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886] aminopeptidase activity [GO:0004177]; metalloaminopeptidase activity [GO:0070006]; peptide binding [GO:0042277]; zinc ion binding [GO:0008270] 0.95182 -1.3976 ETRITRLPELK 0 0 0 0 8.47249 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.49297 0 Q07092 COGA1_HUMAN Collagen alpha-1(XVI) chain COL16A1 FP1572 Homo sapiens (Human) cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cellular response to amino acid stimulus [GO:0071230]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]; positive regulation of focal adhesion assembly [GO:0051894] collagen type IX trimer [GO:0005594]; collagen type XVI trimer [GO:0005597]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020]; integrin binding [GO:0005178] 0.88258 -0.061746 AGERGLKGQK 10.3595 0 9.9737 0 0 0 0 9.92122 0 9.76772 0 0 0 0 0 10.4574 11.6431 0 0 10.1483 0 0 0 0 0 10.5325 10.5828 Q07157 ZO1_HUMAN Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1) TJP1 ZO1 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; adherens junction maintenance [GO:0034334]; cell-cell adhesion [GO:0098609]; cell-cell junction assembly [GO:0007043]; cell-cell junction organization [GO:0045216]; establishment of endothelial intestinal barrier [GO:0090557]; maintenance of blood-brain barrier [GO:0035633]; negative regulation of apoptotic process [GO:0043066]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of blood-brain barrier permeability [GO:1905605]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of sprouting angiogenesis [GO:1903672]; protein localization to adherens junction [GO:0071896]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell-cell junction [GO:0150105]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cell junction assembly [GO:1901888]; regulation of cytoskeleton organization [GO:0051493] adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; gap junction [GO:0005921]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; tight junction [GO:0070160] cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; cell adhesion molecule binding [GO:0050839] 0.88425 -0.20916 EAIQQQQNQLVWVSEGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0547 0 0 0 10.1293 0 Q07283 TRHY_HUMAN Trichohyalin TCHH THH THL TRHY Homo sapiens (Human) intermediate filament organization [GO:0045109]; keratinization [GO:0031424] cornified envelope [GO:0001533]; cytoskeleton [GO:0005856]; cytosol [GO:0005829] calcium ion binding [GO:0005509]; transition metal ion binding [GO:0046914] 0.96944 -7.2836 DNKVYCKGR 0 0 0 10.9069 0 0 0 0 0 10.5412 0 0 9.56136 0 0 10.9979 0 0 11.0211 10.7979 9.7224 0 0 0 10.9449 0 10.9609 Q07343 PDE4B_HUMAN "cAMP-specific 3',5'-cyclic phosphodiesterase 4B (EC 3.1.4.53) (DPDE4) (PDE32)" PDE4B DPDE4 Homo sapiens (Human) cAMP catabolic process [GO:0006198]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to xenobiotic stimulus [GO:0071466]; leukocyte migration [GO:0050900]; negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process [GO:0140199]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of type II interferon production [GO:0032729]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852] centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018] "3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; metal ion binding [GO:0046872]; transmembrane transporter binding [GO:0044325]" 0.85608 0.10409 QNDVEIPSPTQKDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.0964 0 0 0 0 0 0 0 0 Q075Z2 BSPH1_HUMAN Binder of sperm protein homolog 1 (Bovine seminal plasma protein homolog 1) (Bovine seminal plasma protein-like 1) BSPH1 Homo sapiens (Human) single fertilization [GO:0007338]; sperm capacitation [GO:0048240] cell surface [GO:0009986]; extracellular region [GO:0005576] heparin binding [GO:0008201] 0.93297 -1.2849 NFNKDRIWK 0 0 0 0 0 12.4167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q07617 SPAG1_HUMAN Sperm-associated antigen 1 (HSD-3.8) (Infertility-related sperm protein Spag-1) SPAG1 Homo sapiens (Human) axonemal dynein complex assembly [GO:0070286]; protein stabilization [GO:0050821]; single fertilization [GO:0007338] cytoplasm [GO:0005737]; cytosol [GO:0005829]; dynein axonemal particle [GO:0120293]; protein folding chaperone complex [GO:0101031] GTP binding [GO:0005525]; hydrolase activity [GO:0016787] 0.88547 -0.38185 HEDGGGDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.75049 0 9.16267 0 0 0 Q07666 KHDR1_HUMAN "KH domain-containing, RNA-binding, signal transduction-associated protein 1 (GAP-associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p21 Ras GTPase-activating protein-associated p62) (p68)" KHDRBS1 SAM68 Homo sapiens (Human) "G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; mRNA processing [GO:0006397]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of RNA export from nucleus [GO:0046833]; positive regulation of translational initiation [GO:0045948]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of RNA export from nucleus [GO:0046831]; spermatogenesis [GO:0007283]; T cell receptor signaling pathway [GO:0050852]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; Grb2-Sos complex [GO:0070618]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] DNA binding [GO:0003677]; identical protein binding [GO:0042802]; mRNA binding [GO:0003729]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein domain specific binding [GO:0019904]; protein tyrosine kinase binding [GO:1990782]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; signaling adaptor activity [GO:0035591] 0.005848 2.3525 GALVRGTPVR 0 0 0 0 0 0 0 0 8.6606 0 0 0 0 0 9.60235 0 8.9394 13.9546 0 0 0 0 0 0 0 0 0 Q07699 SCN1B_HUMAN Sodium channel subunit beta-1 SCN1B Homo sapiens (Human) axon guidance [GO:0007411]; cardiac conduction [GO:0061337]; cardiac muscle cell action potential involved in contraction [GO:0086002]; cardiac muscle contraction [GO:0060048]; cell adhesion [GO:0007155]; corticospinal neuron axon guidance [GO:0021966]; locomotion [GO:0040011]; membrane depolarization [GO:0051899]; membrane depolarization during cardiac muscle cell action potential [GO:0086012]; membrane depolarization during Purkinje myocyte cell action potential [GO:0086047]; neuronal action potential propagation [GO:0019227]; positive regulation of neuron projection development [GO:0010976]; positive regulation of sodium ion transport [GO:0010765]; regulation of atrial cardiac muscle cell membrane depolarization [GO:0060371]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of sodium ion transmembrane transporter activity [GO:2000649]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; sodium ion transmembrane transport [GO:0035725] extracellular region [GO:0005576]; intercalated disc [GO:0014704]; node of Ranvier [GO:0033268]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; T-tubule [GO:0030315]; voltage-gated sodium channel complex [GO:0001518] sodium channel inhibitor activity [GO:0019871]; sodium channel regulator activity [GO:0017080]; voltage-gated monoatomic ion channel activity [GO:0005244]; voltage-gated sodium channel activity [GO:0005248]; voltage-gated sodium channel activity involved in cardiac muscle cell action potential [GO:0086006]; voltage-gated sodium channel activity involved in Purkinje myocyte action potential [GO:0086062] 0.91617 -0.76809 ILCISCKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4952 0 0 0 0 0 Q07820 MCL1_HUMAN Induced myeloid leukemia cell differentiation protein Mcl-1 (Bcl-2-like protein 3) (Bcl2-L-3) (Bcl-2-related protein EAT/mcl1) (mcl1/EAT) MCL1 BCL2L3 Homo sapiens (Human) cell fate determination [GO:0001709]; cellular homeostasis [GO:0019725]; DNA damage response [GO:0006974]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitochondrial fusion [GO:0008053]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; positive regulation of apoptotic process [GO:0043065]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; regulation of apoptotic process [GO:0042981]; release of cytochrome c from mitochondria [GO:0001836]; response to cytokine [GO:0034097] Bcl-2 family protein complex [GO:0097136]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] BH3 domain binding [GO:0051434]; channel activity [GO:0015267]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein transmembrane transporter activity [GO:0008320] 0.92313 -1.1468 DTKPMGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.43093 0 0 0 0 0 0 0 Q07864 DPOE1_HUMAN DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (3'-5' exodeoxyribonuclease) (EC 3.1.11.-) (DNA polymerase II subunit A) POLE POLE1 Homo sapiens (Human) "base-excision repair, gap-filling [GO:0006287]; DNA replication [GO:0006260]; DNA replication proofreading [GO:0045004]; DNA synthesis involved in DNA repair [GO:0000731]; DNA-templated DNA replication [GO:0006261]; embryonic organ development [GO:0048568]; G1/S transition of mitotic cell cycle [GO:0000082]; leading strand elongation [GO:0006272]; mitotic cell cycle [GO:0000278]; nucleotide-excision repair, DNA gap filling [GO:0006297]" epsilon DNA polymerase complex [GO:0008622]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] "4 iron, 4 sulfur cluster binding [GO:0051539]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; nucleotide binding [GO:0000166]; single-stranded DNA 3'-5' DNA exonuclease activity [GO:0008310]; zinc ion binding [GO:0008270]" 0.96871 -7.6966 LLEKNDVYK 0 0 0 0 0 0 0 0 0 0 9.85574 0 0 0 0 0 0 0 0 0 9.46769 0 8.70477 0 10.7232 0 0 Q07866 KLC1_HUMAN Kinesin light chain 1 (KLC 1) KLC1 KLC KNS2 Homo sapiens (Human) cell adhesion [GO:0007155]; microtubule-based movement [GO:0007018]; stress granule disassembly [GO:0035617] cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; growth cone [GO:0030426]; kinesin complex [GO:0005871]; membrane [GO:0016020]; microtubule [GO:0005874] cytoskeletal motor activity [GO:0003774]; kinesin binding [GO:0019894] 0.93988 -1.3006 KDDESNLVEEK 11.9201 0 0 9.07114 0 0 10.1343 0 0 0 0 0 0 9.66046 0 0 0 0 0 0 0 0 8.77785 0 0 0 9.69697 Q07869 PPARA_HUMAN Peroxisome proliferator-activated receptor alpha (PPAR-alpha) (Nuclear receptor subfamily 1 group C member 1) PPARA NR1C1 PPAR Homo sapiens (Human) behavioral response to nicotine [GO:0035095]; cell differentiation [GO:0030154]; cellular response to starvation [GO:0009267]; circadian regulation of gene expression [GO:0032922]; enamel mineralization [GO:0070166]; epidermis development [GO:0008544]; fatty acid metabolic process [GO:0006631]; gluconeogenesis [GO:0006094]; heart development [GO:0007507]; hormone-mediated signaling pathway [GO:0009755]; lipid localization [GO:0010876]; lipoprotein metabolic process [GO:0042157]; negative regulation of appetite [GO:0032099]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of glycolytic process [GO:0045820]; negative regulation of hepatocyte apoptotic process [GO:1903944]; negative regulation of inflammatory response [GO:0050728]; negative regulation of leukocyte cell-cell adhesion [GO:1903038]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of miRNA transcription [GO:1902894]; negative regulation of neuron death [GO:1901215]; negative regulation of protein binding [GO:0032091]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of sequestering of triglyceride [GO:0010891]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of fatty acid oxidation [GO:0046321]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of viral genome replication [GO:0045070]; regulation of cellular ketone metabolic process [GO:0010565]; regulation of circadian rhythm [GO:0042752]; regulation of fatty acid metabolic process [GO:0019217]; regulation of fatty acid transport [GO:2000191]; regulation of lipid metabolic process [GO:0019216]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to insulin [GO:0032868]; wound healing [GO:0042060] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription factor binding [GO:0140297]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; lipid binding [GO:0008289]; MDM2/MDM4 family protein binding [GO:0097371]; NFAT protein binding [GO:0051525]; nuclear receptor activity [GO:0004879]; nuclear steroid receptor activity [GO:0003707]; phosphatase binding [GO:0019902]; protein domain specific binding [GO:0019904]; protein-containing complex binding [GO:0044877]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific DNA binding [GO:0043565]; transcription coactivator binding [GO:0001223]; ubiquitin conjugating enzyme binding [GO:0031624]; zinc ion binding [GO:0008270]" 0.89887 -0.57519 FGRMPRSEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0612 0 0 0 0 0 0 0 0 0 0 0 0 Q07889 SOS1_HUMAN Son of sevenless homolog 1 (SOS-1) SOS1 Homo sapiens (Human) axon guidance [GO:0007411]; B cell homeostasis [GO:0001782]; B cell receptor signaling pathway [GO:0050853]; blood vessel morphogenesis [GO:0048514]; cardiac atrium morphogenesis [GO:0003209]; cytokine-mediated signaling pathway [GO:0019221]; epidermal growth factor receptor signaling pathway [GO:0007173]; eyelid development in camera-type eye [GO:0061029]; Fc-epsilon receptor signaling pathway [GO:0038095]; fibroblast growth factor receptor signaling pathway [GO:0008543]; hair follicle development [GO:0001942]; heart trabecula morphogenesis [GO:0061384]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; leukocyte migration [GO:0050900]; midbrain morphogenesis [GO:1904693]; multicellular organism growth [GO:0035264]; neurotrophin TRK receptor signaling pathway [GO:0048011]; pericardium morphogenesis [GO:0003344]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of GTPase activity [GO:0043547]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; Ras protein signal transduction [GO:0007265]; regulation of cell population proliferation [GO:0042127]; regulation of MAP kinase activity [GO:0043405]; regulation of pro-B cell differentiation [GO:2000973]; regulation of T cell differentiation in thymus [GO:0033081]; regulation of T cell proliferation [GO:0042129]; regulation of transcription by RNA polymerase II [GO:0006357]; response to ischemia [GO:0002931]; roof of mouth development [GO:0060021]; signal transduction [GO:0007165]; vitellogenesis [GO:0007296] cytoplasm [GO:0005737]; cytosol [GO:0005829]; GTPase complex [GO:1905360]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] epidermal growth factor receptor binding [GO:0005154]; GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; protein heterodimerization activity [GO:0046982]; SH3 domain binding [GO:0017124] 0.96742 -2.8202 NPKPLPRFPK 10.4107 10.4339 0 0 0 0 11.9559 11.948 0 11.3869 11.4751 0 12.3812 12.3054 12.6783 0 0 0 0 10.7774 0 0 10.2229 0 0 0 0 Q07890 SOS2_HUMAN Son of sevenless homolog 2 (SOS-2) SOS2 Homo sapiens (Human) B cell homeostasis [GO:0001782]; insulin receptor signaling pathway [GO:0008286]; positive regulation of GTPase activity [GO:0043547]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; Ras protein signal transduction [GO:0007265]; regulation of pro-B cell differentiation [GO:2000973]; regulation of T cell differentiation in thymus [GO:0033081]; regulation of T cell proliferation [GO:0042129] cytosol [GO:0005829]; plasma membrane [GO:0005886] guanyl-nucleotide exchange factor activity [GO:0005085]; protein heterodimerization activity [GO:0046982] 0.88746 -0.35295 GEQPISADLK 0 0 0 0 0 0 10.0975 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q07912 ACK1_HUMAN Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2) TNK2 ACK1 Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; endocytosis [GO:0006897]; phosphorylation [GO:0016310]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; protein phosphorylation [GO:0006468]; regulation of clathrin-dependent endocytosis [GO:2000369]; small GTPase mediated signal transduction [GO:0007264] adherens junction [GO:0005912]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; cytoophidium [GO:0097268]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; endosome [GO:0005768]; Grb2-EGFR complex [GO:0070436]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; epidermal growth factor receptor binding [GO:0005154]; GTPase inhibitor activity [GO:0005095]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein tyrosine kinase activity [GO:0004713]; ubiquitin protein ligase binding [GO:0031625]; WW domain binding [GO:0050699] 0.92595 -0.96264 IDKEGER 12.085 0 0 0 0 0 10.2457 0 0 0 0 0 0 0 10.7519 0 0 0 8.16646 0 0 0 0 0 0 0 10.456 Q07954 LRP1_HUMAN Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)] LRP1 A2MR APR Homo sapiens (Human) amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta clearance by transcytosis [GO:0150093]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; astrocyte activation involved in immune response [GO:0002265]; cellular response to amyloid-beta [GO:1904646]; enzyme-linked receptor protein signaling pathway [GO:0007167]; lipid metabolic process [GO:0006629]; lipoprotein transport [GO:0042953]; lysosomal transport [GO:0007041]; negative regulation of gene expression [GO:0010629]; negative regulation of metallopeptidase activity [GO:1905049]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of SMAD protein signal transduction [GO:0060392]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; phagocytosis [GO:0006909]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cholesterol transport [GO:0032376]; positive regulation of endocytosis [GO:0045807]; positive regulation of lipid transport [GO:0032370]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of transcytosis [GO:1904300]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of phospholipase A2 activity [GO:0032429]; retinoid metabolic process [GO:0001523]; transcytosis [GO:0045056]; transport across blood-brain barrier [GO:0150104] basolateral plasma membrane [GO:0016323]; clathrin-coated pit [GO:0005905]; cytoskeleton [GO:0005856]; early endosome [GO:0005769]; endocytic vesicle membrane [GO:0030666]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; low-density lipoprotein receptor complex [GO:0062136]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; plasma membrane protein complex [GO:0098797]; receptor complex [GO:0043235] alpha-2 macroglobulin receptor activity [GO:0016964]; amyloid-beta binding [GO:0001540]; apolipoprotein binding [GO:0034185]; apolipoprotein receptor activity [GO:0030226]; calcium ion binding [GO:0005509]; cargo receptor activity [GO:0038024]; clathrin heavy chain binding [GO:0032050]; heparan sulfate proteoglycan binding [GO:0043395]; lipoprotein particle receptor binding [GO:0070325]; low-density lipoprotein particle receptor activity [GO:0005041]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; scavenger receptor activity [GO:0005044]; signaling receptor activity [GO:0038023] 0.9482 -1.3628 DKKEFLCR 0 10.4821 0 0 8.85941 0 0 0 0 0 0 0 12.248 0 10.2388 0 0 10.9386 0 0 0 0 0 0 0 0 11.0266 Q07955 SRSF1_HUMAN "Serine/arginine-rich splicing factor 1 (Alternative-splicing factor 1) (ASF-1) (Splicing factor, arginine/serine-rich 1) (pre-mRNA-splicing factor SF2, P33 subunit)" SRSF1 ASF SF2 SF2P33 SFRS1 OK/SW-cl.3 Homo sapiens (Human) "alternative mRNA splicing, via spliceosome [GO:0000380]; mRNA 5'-splice site recognition [GO:0000395]; mRNA processing [GO:0006397]; mRNA splice site selection [GO:0006376]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; regulation of RNA splicing [GO:0043484]" catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA topoisomerase binding [GO:0044547]; mRNA binding [GO:0003729]; RNA binding [GO:0003723] 0.020179 1.5759 DGTGVVEFVR 0 8.49345 8.43821 0 0 0 8.9712 0 0 0 0 0 0 0 0 9.88443 10.0045 9.65516 10.294 0 0 0 0 0 0 10.6903 10.8671 Q07973 CP24A_HUMAN "1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial (24-OHase) (Vitamin D(3) 24-hydroxylase) (EC 1.14.15.16) (Cytochrome P450 24A1) (Cytochrome P450-CC24)" CYP24A1 CYP24 Homo sapiens (Human) osteoblast differentiation [GO:0001649]; response to vitamin D [GO:0033280]; vitamin D catabolic process [GO:0042369]; vitamin D metabolic process [GO:0042359]; vitamin D receptor signaling pathway [GO:0070561]; vitamin metabolic process [GO:0006766] mitochondrial inner membrane [GO:0005743] "1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity [GO:0062181]; 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity [GO:0030342]; 25-hydroxycholecalciferol-23-hydroxylase activity [GO:0062180]; 25-hydroxycholecalciferol-24-hydroxylase activity [GO:0008403]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; vitamin D 25-hydroxylase activity [GO:0070643]" 0.94731 -1.3585 KQHDTLVEYHKK 0 0 8.2597 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q08043 ACTN3_HUMAN Alpha-actinin-3 (Alpha-actinin skeletal muscle isoform 3) (F-actin cross-linking protein) ACTN3 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; bone morphogenesis [GO:0060349]; focal adhesion assembly [GO:0048041]; muscle cell development [GO:0055001]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of glycolytic process [GO:0045820]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of relaxation of muscle [GO:1901078]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of fast-twitch skeletal muscle fiber contraction [GO:0031448]; positive regulation of glucose catabolic process to lactate via pyruvate [GO:1904025]; positive regulation of skeletal muscle fiber development [GO:0048743]; positive regulation of skeletal muscle tissue growth [GO:0048633]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of the force of skeletal muscle contraction [GO:0014728]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; skeletal muscle atrophy [GO:0014732]; transition between fast and slow fiber [GO:0014883] actin filament [GO:0005884]; brush border [GO:0005903]; cell junction [GO:0030054]; cell projection [GO:0042995]; cortical actin cytoskeleton [GO:0030864]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]; Z disc [GO:0030018] actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; structural constituent of muscle [GO:0008307]; transmembrane transporter binding [GO:0044325] 0.90794 -0.74076 ALDFIASK 0 0 0 0 0 9.64283 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q08170 SRSF4_HUMAN "Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)" SRSF4 SFRS4 SRP75 Homo sapiens (Human) "mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; response to insulin [GO:0032868]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]" nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] RNA binding [GO:0003723]; sequence-specific mRNA binding [GO:1990825] 0.93045 -1.2473 LIVENLSSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6898 Q08174 PCDH1_HUMAN Protocadherin-1 (Cadherin-like protein 1) (Protocadherin-42) (PC42) PCDH1 Homo sapiens (Human) cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399] cell junction [GO:0030054]; cell-cell junction [GO:0005911]; intracellular membrane-bounded organelle [GO:0043231]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.94064 -1.3287 YCRQREAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.15921 0 0 0 Q08188 TGM3_HUMAN Protein-glutamine gamma-glutamyltransferase E (EC 2.3.2.13) (Transglutaminase E) (TG(E)) (TGE) (TGase E) (Transglutaminase-3) (TGase-3) [Cleaved into: Protein-glutamine gamma-glutamyltransferase E 50 kDa catalytic chain; Protein-glutamine gamma-glutamyltransferase E 27 kDa non-catalytic chain] TGM3 Homo sapiens (Human) cell envelope organization [GO:0043163]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein modification process [GO:0036211] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; protein-containing complex [GO:0032991] acyltransferase activity [GO:0016746]; calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; structural molecule activity [GO:0005198] 0.95456 -1.6155 FDILPSRSGTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.616 0 Q08209 PP2BA_HUMAN Protein phosphatase 3 catalytic subunit alpha (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calcineurin A alpha) (Calmodulin-dependent calcineurin A subunit alpha isoform) (CNA alpha) (Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform) PPP3CA CALNA CNA Homo sapiens (Human) aging [GO:0007568]; brain development [GO:0007420]; calcineurin-mediated signaling [GO:0097720]; calcineurin-NFAT signaling cascade [GO:0033173]; calcium ion transport [GO:0006816]; cardiac muscle hypertrophy in response to stress [GO:0014898]; cellular response to glucose stimulus [GO:0071333]; dendrite morphogenesis [GO:0048813]; dephosphorylation [GO:0016311]; epidermis development [GO:0008544]; excitatory postsynaptic potential [GO:0060079]; G1/S transition of mitotic cell cycle [GO:0000082]; keratinocyte differentiation [GO:0030216]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of calcium ion import across plasma membrane [GO:1905949]; negative regulation of chromatin binding [GO:0035562]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of gene expression [GO:0010629]; negative regulation of insulin secretion [GO:0046676]; negative regulation of signaling [GO:0023057]; negative regulation of voltage-gated calcium channel activity [GO:1901386]; peptidyl-serine dephosphorylation [GO:0070262]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of calcium ion import across plasma membrane [GO:1905665]; positive regulation of cardiac muscle hypertrophy in response to stress [GO:1903244]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of connective tissue replacement [GO:1905205]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endocytosis [GO:0045807]; positive regulation of gene expression [GO:0010628]; positive regulation of glomerulus development [GO:0090193]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of saliva secretion [GO:0046878]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein dephosphorylation [GO:0006470]; protein import into nucleus [GO:0006606]; regulation of cell proliferation involved in kidney morphogenesis [GO:0061006]; renal filtration [GO:0097205]; response to amphetamine [GO:0001975]; response to calcium ion [GO:0051592]; skeletal muscle fiber development [GO:0048741]; skeletal muscle tissue regeneration [GO:0043403]; T cell activation [GO:0042110]; transition between fast and slow fiber [GO:0014883]; wound healing [GO:0042060] calcineurin complex [GO:0005955]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extrinsic component of plasma membrane [GO:0019897]; glutamatergic synapse [GO:0098978]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein serine/threonine phosphatase complex [GO:0008287]; sarcolemma [GO:0042383]; Schaffer collateral - CA1 synapse [GO:0098685]; slit diaphragm [GO:0036057]; Z disc [GO:0030018] ATPase binding [GO:0051117]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; calmodulin-dependent protein phosphatase activity [GO:0033192]; cyclosporin A binding [GO:0016018]; enzyme binding [GO:0019899]; molecular function activator activity [GO:0140677]; myosin phosphatase activity [GO:0017018]; protein dimerization activity [GO:0046983]; protein serine/threonine phosphatase activity [GO:0004722]; protein-containing complex binding [GO:0044877] 0.89906 -0.64636 ITSFEEAKGLDR 0 9.49633 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q08211 DHX9_HUMAN ATP-dependent RNA helicase A (EC 3.6.4.13) (DEAH box protein 9) (DExH-box helicase 9) (Leukophysin) (LKP) (Nuclear DNA helicase II) (NDH II) (RNA helicase A) DHX9 DDX9 LKP NDH2 Homo sapiens (Human) "alternative mRNA splicing, via spliceosome [GO:0000380]; cellular response to exogenous dsRNA [GO:0071360]; cellular response to tumor necrosis factor [GO:0071356]; CRD-mediated mRNA stabilization [GO:0070934]; DNA duplex unwinding [GO:0032508]; DNA replication [GO:0006260]; DNA-templated transcription termination [GO:0006353]; DNA-templated viral transcription [GO:0039695]; G-quadruplex DNA unwinding [GO:0044806]; global gene silencing by mRNA cleavage [GO:0098795]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; mRNA transport [GO:0051028]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; osteoblast differentiation [GO:0001649]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity [GO:2000373]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of inflammatory response [GO:0050729]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-18 production [GO:0032741]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of polysome binding [GO:1905698]; positive regulation of response to cytokine stimulus [GO:0060760]; positive regulation of RNA export from nucleus [GO:0046833]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of viral transcription [GO:0050434]; positive regulation of viral translation [GO:1904973]; protein localization to cytoplasmic stress granule [GO:1903608]; protein-containing complex assembly [GO:0065003]; pyroptosis [GO:0070269]; regulation of cytoplasmic translation [GO:2000765]; regulation of defense response to virus by host [GO:0050691]; regulation of mRNA processing [GO:0050684]; regulation of transcription by RNA polymerase II [GO:0006357]; rhythmic process [GO:0048511]; RISC complex assembly [GO:0070922]; RNA secondary structure unwinding [GO:0010501]" actin cytoskeleton [GO:0015629]; centrosome [GO:0005813]; CRD-mediated mRNA stability complex [GO:0070937]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; membrane [GO:0016020]; nuclear body [GO:0016604]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perichromatin fibrils [GO:0005726]; polysomal ribosome [GO:0042788]; polysome [GO:0005844]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; RISC complex [GO:0016442]; RISC-loading complex [GO:0070578] 3'-5' DNA helicase activity [GO:0043138]; 3'-5' DNA/RNA helicase activity [GO:0033679]; 3'-5' RNA helicase activity [GO:0034458]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; DNA replication origin binding [GO:0003688]; double-stranded DNA binding [GO:0003690]; double-stranded RNA binding [GO:0003725]; importin-alpha family protein binding [GO:0061676]; metal ion binding [GO:0046872]; mRNA binding [GO:0003729]; nucleoside triphosphate diphosphatase activity [GO:0047429]; polysome binding [GO:1905538]; promoter-specific chromatin binding [GO:1990841]; regulatory region RNA binding [GO:0001069]; ribonucleoside triphosphate phosphatase activity [GO:0017111]; RISC complex binding [GO:1905172]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA polymerase binding [GO:0070063]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; RNA stem-loop binding [GO:0035613]; sequence-specific mRNA binding [GO:1990825]; single-stranded 3'-5' DNA helicase activity [GO:1990518]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; siRNA binding [GO:0035197]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; triplex DNA binding [GO:0045142] 0 4.182 AAMEALVVEVTK 9.02129 0 0 0 9.46683 0 9.18053 0 0 10.4183 8.63539 10.7478 10.0794 10.2795 0 9.63007 10.602 9.77614 9.11413 9.13486 0 9.18894 0 9.29928 11.3668 10.533 12.0129 Q08257 QOR_HUMAN Quinone oxidoreductase (EC 1.6.5.5) (NADPH:quinone reductase) (Zeta-crystallin) CRYZ Homo sapiens (Human) protein homotetramerization [GO:0051289]; visual perception [GO:0007601]; xenobiotic catabolic process [GO:0042178] cytosol [GO:0005829]; extracellular exosome [GO:0070062] identical protein binding [GO:0042802]; mRNA 3'-UTR binding [GO:0003730]; NADPH binding [GO:0070402]; NADPH:quinone reductase activity [GO:0003960]; zinc ion binding [GO:0008270] 0.11193 1.1223 EVNYIDK 0 0 0 0 0 0 0 0 0 11.5314 11.738 0 0 0 0 0 8.74457 0 9.42727 0 0 0 0 0 0 0 0 Q08334 I10R2_HUMAN Interleukin-10 receptor subunit beta (IL-10 receptor subunit beta) (IL-10R subunit beta) (IL-10RB) (Cytokine receptor class-II member 4) (Cytokine receptor family 2 member 4) (CRF2-4) (Interleukin-10 receptor subunit 2) (IL-10R subunit 2) (IL-10R2) (CD antigen CDw210b) IL10RB CRFB4 D21S58 D21S66 Homo sapiens (Human) cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; immune response [GO:0006955]; inflammatory response [GO:0006954]; positive regulation of cellular respiration [GO:1901857]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; signal transduction [GO:0007165]; type III interferon-mediated signaling pathway [GO:0038196] interleukin-28 receptor complex [GO:0032002]; membrane [GO:0016020]; plasma membrane [GO:0005886] interleukin-10 receptor activity [GO:0004920]; signaling receptor activity [GO:0038023] 0.83094 0.20203 IFQDKCMNTTLTECDFSSLSK 0 0 0 0 0 0 0 0 0 0 0 11.4464 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q08345 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a) DDR1 CAK EDDR1 NEP NTRK4 PTK3A RTK6 TRKE Homo sapiens (Human) "axon development [GO:0061564]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; ear development [GO:0043583]; embryo implantation [GO:0007566]; lactation [GO:0007595]; mammary gland alveolus development [GO:0060749]; negative regulation of cell population proliferation [GO:0008285]; neuron projection extension [GO:1990138]; peptidyl-tyrosine autophosphorylation [GO:0038083]; positive regulation of kinase activity [GO:0033674]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; protein autophosphorylation [GO:0046777]; regulation of cell growth [GO:0001558]; regulation of cell-matrix adhesion [GO:0001952]; regulation of extracellular matrix disassembly [GO:0010715]; smooth muscle cell migration [GO:0014909]; smooth muscle cell-matrix adhesion [GO:0061302]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing, spreading of cells [GO:0044319]" extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] ATP binding [GO:0005524]; collagen binding [GO:0005518]; metal ion binding [GO:0046872]; protein tyrosine kinase collagen receptor activity [GO:0038062]; transmembrane receptor protein tyrosine kinase activity [GO:0004714] 0.064386 1.3108 DLGPPMVAR 0 0 0 0 0 0 0 0 0 0 0 13.453 8.54245 0 0 0 0 0 0 0 0 11.9356 0 0 0 0 0 Q08357 S20A2_HUMAN Sodium-dependent phosphate transporter 2 (Gibbon ape leukemia virus receptor 2) (GLVR-2) (Phosphate transporter 2) (PiT-2) (Pit2) (hPit2) (Solute carrier family 20 member 2) SLC20A2 GLVR2 PIT2 Homo sapiens (Human) monoatomic ion transport [GO:0006811]; phosphate ion transmembrane transport [GO:0035435]; positive regulation of bone mineralization [GO:0030501] apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886] inorganic phosphate transmembrane transporter activity [GO:0005315]; signaling receptor activity [GO:0038023]; sodium:phosphate symporter activity [GO:0005436]; virus receptor activity [GO:0001618] 0.81772 0.22016 VQEAESPVFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.82967 0 0 0 0 0 Q08378 GOGA3_HUMAN Golgin subfamily A member 3 (Golgi complex-associated protein of 170 kDa) (GCP170) (Golgin-160) GOLGA3 Homo sapiens (Human) cytosol [GO:0005829]; extrinsic component of Golgi membrane [GO:0090498]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] cadherin binding [GO:0045296] 0.95924 -1.9141 AQLQLLQK 0 9.30118 0 0 0 0 14.9258 0 0 0 0 8.92985 0 0 8.75786 0 0 0 0 0 0 0 0 0 0 0 0 Q08379 GOGA2_HUMAN Golgin subfamily A member 2 (130 kDa cis-Golgi matrix protein) (GM130) (GM130 autoantigen) (Golgin-95) GOLGA2 Homo sapiens (Human) asymmetric cell division [GO:0008356]; centrosome cycle [GO:0007098]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi disassembly [GO:0090166]; Golgi organization [GO:0007030]; Golgi ribbon formation [GO:0090161]; meiotic spindle assembly [GO:0090306]; microtubule nucleation [GO:0007020]; mitotic spindle assembly [GO:0090307]; negative regulation of autophagy [GO:0010507]; negative regulation of protein binding [GO:0032091]; positive regulation of protein glycosylation [GO:0060050]; protein glycosylation [GO:0006486]; protein homotetramerization [GO:0051289]; protein transport [GO:0015031]; spindle assembly [GO:0051225] cis-Golgi network [GO:0005801]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; Golgi apparatus [GO:0005794]; Golgi cis cisterna [GO:0000137]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; microtubule [GO:0005874]; mitotic spindle [GO:0072686]; spindle pole [GO:0000922] cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; importin-alpha family protein binding [GO:0061676]; microtubule binding [GO:0008017]; protein kinase binding [GO:0019901]; syntaxin binding [GO:0019905] 0.96892 -4.1986 ADLKERVEELEHR 9.36685 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.4567 0 0 10.7093 0 0 0 0 0 Q08380 LG3BP_HUMAN Galectin-3-binding protein (Basement membrane autoantigen p105) (Lectin galactoside-binding soluble 3-binding protein) (Mac-2-binding protein) (MAC2BP) (Mac-2 BP) (Tumor-associated antigen 90K) LGALS3BP M2BP Homo sapiens (Human) cell adhesion [GO:0007155]; cellular defense response [GO:0006968]; signal transduction [GO:0007165] blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet dense granule lumen [GO:0031089] scavenger receptor activity [GO:0005044] 0.16216 0.99979 LADGGATNQGR 8.80407 9.12407 9.27123 0 0 0 9.84532 9.90323 9.92585 0 0 0 0 0 0 10.2079 0 0 0 8.60951 0 8.83267 8.48002 10.2727 10.2377 9.80678 9.84405 Q08397 LOXL1_HUMAN Lysyl oxidase homolog 1 (EC 1.4.3.-) (Lysyl oxidase-like protein 1) (LOL) LOXL1 LOXL Homo sapiens (Human) aorta development [GO:0035904]; collagen fibril organization [GO:0030199]; peptidyl-lysine oxidation [GO:0018057]; protein deamination [GO:0018277]; response to lipopolysaccharide [GO:0032496] acrosomal vesicle [GO:0001669]; basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615] copper ion binding [GO:0005507]; protein-lysine 6-oxidase activity [GO:0004720] 0.91437 -0.78256 CNIHYTGRYVSATNCK 0 0 0 0 0 0 0 0 0 0 12.6967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q08431 MFGM_HUMAN Lactadherin (Breast epithelial antigen BA46) (HMFG) (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) [Cleaved into: Lactadherin short form; Medin] MFGE8 Homo sapiens (Human) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; single fertilization [GO:0007338] acrosomal membrane [GO:0002080]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; membrane [GO:0016020] integrin binding [GO:0005178]; phosphatidylserine binding [GO:0001786] 0.072692 1.276 EFVGNWNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.95536 0 10.1371 0 0 9.50369 0 0 0 0 0 0 0 Q08462 ADCY2_HUMAN Adenylate cyclase type 2 (EC 4.6.1.1) (ATP pyrophosphate-lyase 2) (Adenylate cyclase type II) (Adenylyl cyclase 2) ADCY2 KIAA1060 Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cAMP biosynthetic process [GO:0006171]; cAMP-mediated signaling [GO:0019933]; cellular response to forskolin [GO:1904322] cytoplasm [GO:0005737]; dendrite [GO:0030425]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886] adenylate cyclase activity [GO:0004016]; adenylate cyclase binding [GO:0008179]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145] 0.92747 -1.2173 TYFVINPKGERR 0 0 0 0 0 0 0 0 0 0 0 0 0 16.0788 0 0 0 0 0 0 0 0 0 0 11.0554 0 0 Q08477 CP4F3_HUMAN Cytochrome P450 4F3 (EC 1.14.14.1) (20-hydroxyeicosatetraenoic acid synthase) (20-HETE synthase) (CYPIVF3) (Cytochrome P450-LTB-omega) (Docosahexaenoic acid omega-hydroxylase CYP4F3) (EC 1.14.14.79) (Leukotriene-B(4) 20-monooxygenase 2) (Leukotriene-B(4) omega-hydroxylase 2) (EC 1.14.14.94) CYP4F3 LTB4H Homo sapiens (Human) arachidonic acid metabolic process [GO:0019369]; fatty acid omega-oxidation [GO:0010430]; icosanoid metabolic process [GO:0006690]; leukotriene B4 catabolic process [GO:0036101]; leukotriene metabolic process [GO:0006691]; lipoxin A4 metabolic process [GO:2001302]; lipoxin B4 metabolic process [GO:2001304]; omega-hydroxylase P450 pathway [GO:0097267] endoplasmic reticulum membrane [GO:0005789] 20-aldehyde-leukotriene B4 20-monooxygenase activity [GO:0097259]; 20-hydroxy-leukotriene B4 omega oxidase activity [GO:0097258]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; leukotriene-B4 20-monooxygenase activity [GO:0050051]; long-chain fatty acid omega-1 hydroxylase activity [GO:0120319]; long-chain fatty acid omega-hydroxylase activity [GO:0102033]; monooxygenase activity [GO:0004497]; very long-chain fatty acid omega-hydroxylase activity [GO:0140692] 0.69644 0.37749 LHPPVPAVSR 9.04095 0 0 0 0 0 0 0 0 12.2478 0 0 0 0 11.045 0 0 0 0 0 0 0 0 0 10.4488 0 0 Q08493 PDE4C_HUMAN "cAMP-specific 3',5'-cyclic phosphodiesterase 4C (EC 3.1.4.53) (DPDE1) (PDE21)" PDE4C DPDE1 Homo sapiens (Human) cAMP catabolic process [GO:0006198]; signal transduction [GO:0007165] cilium [GO:0005929]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] "3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]" 0.91361 -0.78338 LSWPVSSCRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.65517 0 0 0 0 0 Q08499 PDE4D_HUMAN "cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.53) (DPDE3) (PDE43)" PDE4D DPDE3 Homo sapiens (Human) adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; establishment of endothelial barrier [GO:0061028]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; positive regulation of type II interferon production [GO:0032729]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; T cell receptor signaling pathway [GO:0050852] apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; cytosol [GO:0005829]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891] "3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; enzyme binding [GO:0019899]; heterocyclic compound binding [GO:1901363]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; transmembrane transporter binding [GO:0044325]" 0.87062 0.03407 EAEGSSAPAR 0 0 0 0 0 0 0 0 0 0 0 9.93496 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q08554 DSC1_HUMAN Desmocollin-1 (Cadherin family member 1) (Desmosomal glycoprotein 2/3) (DG2/DG3) DSC1 CDHF1 Homo sapiens (Human) cell-cell adhesion [GO:0098609]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] cornified envelope [GO:0001533]; desmosome [GO:0030057]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; gap junction [GO:0005921]; membrane [GO:0016020]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.60162 0.44138 HCEDYVCSYNYEGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.588 0 0 0 0 0 0 0 0 Q08629 TICN1_HUMAN Testican-1 (Protein SPOCK) SPOCK1 SPOCK TIC1 TICN1 Homo sapiens (Human) cell adhesion [GO:0007155]; central nervous system neuron differentiation [GO:0021953]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of neuron projection development [GO:0010977]; nervous system development [GO:0007399]; neurogenesis [GO:0022008]; neuron migration [GO:0001764]; regulation of cell growth [GO:0001558] cytoplasm [GO:0005737]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; node of Ranvier [GO:0033268]; postsynaptic density [GO:0014069]; sarcoplasm [GO:0016528] calcium ion binding [GO:0005509]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; metalloendopeptidase inhibitor activity [GO:0008191]; serine-type endopeptidase inhibitor activity [GO:0004867] 0.94633 -1.3517 FDTSILPICKDSLGWMFNK 0 9.45238 9.52195 0 0 0 0 0 0 0 0 10.4389 0 0 0 0 0 0 0 9.38524 0 9.41022 9.37675 9.45818 0 0 0 Q08722 CD47_HUMAN Leukocyte surface antigen CD47 (Antigenic surface determinant protein OA3) (Integrin-associated protein) (IAP) (Protein MER6) (CD antigen CD47) CD47 MER6 Homo sapiens (Human) angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; ATP export [GO:1904669]; cell migration [GO:0016477]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; cellular response to type II interferon [GO:0071346]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [GO:1905450]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of inflammatory response [GO:0050729]; positive regulation of monocyte extravasation [GO:2000439]; positive regulation of phagocytosis [GO:0050766]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell activation [GO:0050870]; regulation of interleukin-10 production [GO:0032653]; regulation of interleukin-12 production [GO:0032655]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]; regulation of type II interferon production [GO:0032649] cell surface [GO:0009986]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821] cell-cell adhesion mediator activity [GO:0098632]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; thrombospondin receptor activity [GO:0070053] 0.33462 0.77599 AVEEPLNAFK 0 0 0 0 0 0 0 0 9.35394 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q08828 ADCY1_HUMAN Adenylate cyclase type 1 (EC 4.6.1.1) (ATP pyrophosphate-lyase 1) (Adenylate cyclase type I) (Adenylyl cyclase 1) (Ca(2+)/calmodulin-activated adenylyl cyclase) ADCY1 Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; axonogenesis [GO:0007409]; brain development [GO:0007420]; cAMP biosynthetic process [GO:0006171]; cAMP-mediated signaling [GO:0019933]; cellular response to calcium ion [GO:0071277]; cellular response to forskolin [GO:1904322]; circadian rhythm [GO:0007623]; long-term memory [GO:0007616]; neuroinflammatory response [GO:0150076]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of long-term synaptic potentiation [GO:1900273]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of circadian rhythm [GO:0042752]; response to lithium ion [GO:0010226]; response to xenobiotic stimulus [GO:0009410] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; membrane raft [GO:0045121]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; presynapse [GO:0098793]; Schaffer collateral - CA1 synapse [GO:0098685] adenylate cyclase activity [GO:0004016]; ATP binding [GO:0005524]; calcium- and calmodulin-responsive adenylate cyclase activity [GO:0008294]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872] 0.88298 -0.29957 AGAPRGGGGGGGGAGEPGGAERAAGTSR 8.7151 8.92855 8.72847 0 0 0 0 0 0 0 0 0 0 10.0382 0 0 0 0 0 9.71641 0 0 0 0 0 8.893 0 Q08881 ITK_HUMAN Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) ITK EMT LYK Homo sapiens (Human) activation of phospholipase C activity [GO:0007202]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular defense response [GO:0006968]; gamma-delta T cell activation [GO:0046629]; intracellular signal transduction [GO:0035556]; NK T cell differentiation [GO:0001865]; positive regulation of cytokine production [GO:0001819]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell receptor signaling pathway [GO:0050852] cell-cell junction [GO:0005911]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715] 0.95572 -1.5401 HYHIKETNDNPK 0 0 0 0 0 0 0 0 10.0908 11.2012 0 0 0 0 0 0 0 0 0 0 0 0 0 9.16267 0 0 0 Q08945 SSRP1_HUMAN FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160) SSRP1 FACT80 Homo sapiens (Human) DNA repair [GO:0006281]; DNA replication [GO:0006260]; nucleosome assembly [GO:0006334]; nucleosome disassembly [GO:0006337]; regulation of chromatin organization [GO:1902275] FACT complex [GO:0035101]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; histone binding [GO:0042393]; nucleosome binding [GO:0031491]; RNA binding [GO:0003723] 0.92435 -1.0249 ASSGLLYPLER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.7681 9.84543 9.96867 0 0 11.5021 0 0 Q08999 RBL2_HUMAN Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (p130) (Retinoblastoma-related protein 2) (RBR-2) (pRb2) RBL2 RB2 Homo sapiens (Human) cell cycle [GO:0007049]; cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression [GO:0010629]; regulation of lipid kinase activity [GO:0043550]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; chromosome [GO:0005694]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; transcription regulator complex [GO:0005667] promoter-specific chromatin binding [GO:1990841]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977] 0.96944 -4.9299 DRTSRDSSPVMR 0 11.98 0 0 0 9.72306 0 0 0 9.66354 0 9.24039 0 0 0 0 0 0 10.0356 0 0 0 0 0 0 0 0 Q08AD1 CAMP2_HUMAN Calmodulin-regulated spectrin-associated protein 2 (Calmodulin-regulated spectrin-associated protein 1-like protein 1) CAMSAP2 CAMSAP1L1 KIAA1078 Homo sapiens (Human) axon development [GO:0061564]; cytoplasmic microtubule organization [GO:0031122]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of microtubule depolymerization [GO:0007026]; regulation of dendrite development [GO:0050773]; regulation of Golgi organization [GO:1903358]; regulation of microtubule polymerization [GO:0031113]; regulation of organelle organization [GO:0033043] ciliary basal body [GO:0036064]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; microtubule end [GO:1990752] calmodulin binding [GO:0005516]; microtubule minus-end binding [GO:0051011]; spectrin binding [GO:0030507] 0.96156 -2.5903 MGDAADPREMRK 0 0 0 0 0 0 0 0 10.1041 0 0 0 0 0 0 0 0 10.435 0 0 0 0 0 0 0 0 0 Q08AF3 SLFN5_HUMAN Schlafen family member 5 SLFN5 Homo sapiens (Human) cell differentiation [GO:0030154] nucleus [GO:0005634] ATP binding [GO:0005524] 0.71328 0.36652 ASEVEKYKDR 0 0 0 0 0 0 0 0 0 0 9.48758 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q08AG5 ZN844_HUMAN Zinc finger protein 844 ZNF844 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.88634 -0.3918 DQNIEDQYKNPRNNLR 0 0 0 0 0 0 0 0 0 0 9.23864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4611 9.60251 Q08AH1 ACSM1_HUMAN "Acyl-coenzyme A synthetase ACSM1, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 1) (Benzoate--CoA ligase) (EC 6.2.1.25) (Butyrate--CoA ligase 1) (Butyryl-coenzyme A synthetase 1) (Lipoate-activating enzyme) (Middle-chain acyl-CoA synthetase 1) (Xenobiotic/medium-chain fatty acid-CoA ligase HXM-B)" ACSM1 BUCS1 LAE MACS1 Homo sapiens (Human) acyl-CoA metabolic process [GO:0006637]; benzoate metabolic process [GO:0018874]; butyrate metabolic process [GO:0019605]; cholesterol homeostasis [GO:0042632]; energy derivation by oxidation of organic compounds [GO:0015980]; fatty acid biosynthetic process [GO:0006633]; fatty acid oxidation [GO:0019395]; xenobiotic metabolic process [GO:0006805] blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759] ATP binding [GO:0005524]; benzoate-CoA ligase activity [GO:0018858]; butyrate-CoA ligase activity [GO:0047760]; CoA-ligase activity [GO:0016405]; decanoate-CoA ligase activity [GO:0102391]; fatty acid ligase activity [GO:0015645]; fatty-acyl-CoA synthase activity [GO:0004321]; GTP binding [GO:0005525]; long-chain fatty acid-CoA ligase activity [GO:0004467]; metal ion binding [GO:0046872] 0.88775 -0.39962 SLSEFGAPR 0 0 0 0 0 0 0 0 0 0 9.90138 9.75266 9.65342 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q08AN1 ZN616_HUMAN Zinc finger protein 616 ZNF616 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96266 -2.1671 CLEPVQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2494 0 0 0 0 0 0 0 0 0 0 0 Q08ER8 ZN543_HUMAN Zinc finger protein 543 ZNF543 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.92716 -1.2195 IGIGPQRGKLLEK 0 0 0 0 0 0 0 0 0 0 0 9.25611 0 0 9.31211 9.08738 8.95594 0 0 0 0 0 0 0 0 0 0 Q08ET2 SIG14_HUMAN Sialic acid-binding Ig-like lectin 14 (Siglec-14) SIGLEC14 UNQ294/PRO333 Homo sapiens (Human) cell adhesion [GO:0007155] ficolin-1-rich granule membrane [GO:0101003]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821] carbohydrate binding [GO:0030246]; sialic acid binding [GO:0033691] 0.49755 0.61634 KNCSLSIGDAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.54913 0 0 0 Q08J23 NSUN2_HUMAN "RNA cytosine C(5)-methyltransferase NSUN2 (EC 2.1.1.-) (Myc-induced SUN domain-containing protein) (Misu) (NOL1/NOP2/Sun domain family member 2) (Substrate of AIM1/Aurora kinase B) (mRNA cytosine C(5)-methyltransferase) (EC 2.1.1.-) (tRNA cytosine C(5)-methyltransferase) (EC 2.1.1.-, EC 2.1.1.203) (tRNA methyltransferase 4 homolog) (hTrm4)" NSUN2 SAKI TRM4 Homo sapiens (Human) cell division [GO:0051301]; hair follicle maturation [GO:0048820]; in utero embryonic development [GO:0001701]; meiotic cell cycle checkpoint signaling [GO:0033313]; mRNA methylation [GO:0080009]; regulation of mRNA export from nucleus [GO:0010793]; regulation of stem cell differentiation [GO:2000736]; spermatid development [GO:0007286]; tRNA methylation [GO:0030488]; tRNA modification [GO:0006400]; tRNA stabilization [GO:0036416] chromatoid body [GO:0033391]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819] mRNA (cytidine-5-)-methyltransferase activity [GO:0062152]; RNA binding [GO:0003723]; tRNA (cytosine-5-)-methyltransferase activity [GO:0016428]; tRNA binding [GO:0000049] 0.83502 0.19196 EILHCLK 0 9.24356 0 0 0 0 0 0 0 0 0 9.80821 11.8298 0 0 0 0 0 10.0464 0 0 0 0 0 0 0 0 Q09013 DMPK_HUMAN Myotonin-protein kinase (MT-PK) (EC 2.7.11.1) (DM-kinase) (DMK) (DM1 protein kinase) (DMPK) (Myotonic dystrophy protein kinase) DMPK DM1PK MDPK Homo sapiens (Human) intracellular calcium ion homeostasis [GO:0006874]; muscle cell apoptotic process [GO:0010657]; nuclear envelope organization [GO:0006998]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]; regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction [GO:0014853]; regulation of heart contraction [GO:0008016]; regulation of myotube differentiation [GO:0010830]; regulation of skeletal muscle contraction by calcium ion signaling [GO:0014722]; regulation of sodium ion transport [GO:0002028]; regulation of synapse structural plasticity [GO:0051823] cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; plasma membrane [GO:0005886]; sarcoplasmic reticulum membrane [GO:0033017] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; myosin phosphatase regulator activity [GO:0017020]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.94783 -1.3602 LLCPPETR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.84928 Q09019 DMWD_HUMAN Dystrophia myotonica WD repeat-containing protein (Dystrophia myotonica-containing WD repeat motif protein) (Protein 59) (Protein DMR-N9) DMWD DM9 Homo sapiens (Human) dendrite [GO:0030425]; nucleus [GO:0005634]; perikaryon [GO:0043204] 0.9691 -3.3761 AGSITYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0331 0 0 0 0 0 0 0 0 Q09161 NCBP1_HUMAN Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit) NCBP1 CBP80 NCBP Homo sapiens (Human) "7-methylguanosine mRNA capping [GO:0006370]; alternative mRNA splicing, via spliceosome [GO:0000380]; cap-dependent translational initiation [GO:0002191]; defense response to virus [GO:0051607]; histone mRNA metabolic process [GO:0008334]; miRNA-mediated gene silencing [GO:0035195]; mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transcription by RNA polymerase II [GO:0042789]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell growth [GO:0030307]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of RNA binding [GO:1905216]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; primary miRNA processing [GO:0031053]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA catabolic process [GO:0006401]; RNA splicing [GO:0008380]; snRNA export from nucleus [GO:0006408]; spliceosomal complex assembly [GO:0000245]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA cap binding complex [GO:0034518] molecular adaptor activity [GO:0060090]; mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339] 0.92183 -1.1355 EVLEKCMRLSYHQR 0 0 0 0 0 0 0 0 0 10.2722 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4502 Q09327 MGAT3_HUMAN "Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase (EC 2.4.1.144) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III) (GNT-III) (GlcNAc-T III) (N-acetylglucosaminyltransferase III)" MGAT3 GGNT3 Homo sapiens (Human) amyloid-beta metabolic process [GO:0050435]; cellular response to oxidative stress [GO:0034599]; cognition [GO:0050890]; N-acetylglucosamine metabolic process [GO:0006044]; negative regulation of lysosomal protein catabolic process [GO:1905166]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization [GO:0008104]; protein N-linked glycosylation [GO:0006487]; regulation of cell migration [GO:0030334] Golgi membrane [GO:0000139]; membrane [GO:0016020] "beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity [GO:0003830]; glycosyltransferase activity [GO:0016757]" 0.96478 -2.2828 RPPRYLLSARER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.61453 0 0 0 0 0 0 0 Q09328 MGT5A_HUMAN "Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (EC 2.4.1.155) (Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase V) (GlcNAc-T V) (GNT-V) (Mannoside acetylglucosaminyltransferase 5) (N-acetylglucosaminyl-transferase V) [Cleaved into: Secreted alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (Secreted beta-1,6-N-acetylglucosaminyltransferase V) (Secreted GNT-V)]" MGAT5 GGNT5 Homo sapiens (Human) negative regulation of protein tyrosine phosphatase activity [GO:1903614]; positive regulation of cell migration [GO:0030335]; positive regulation of receptor signaling pathway via STAT [GO:1904894]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]; viral protein processing [GO:0019082] extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020] "alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity [GO:0030144]; manganese ion binding [GO:0030145]; protein phosphatase inhibitor activity [GO:0004864]" 0.96896 -3.9018 CVLPPMDGYPHCEGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.46624 0 0 0 0 Q09428 ABCC8_HUMAN ATP-binding cassette sub-family C member 8 (Sulfonylurea receptor 1) ABCC8 HRINS SUR SUR1 Homo sapiens (Human) cellular response to organic substance [GO:0071310]; female pregnancy [GO:0007565]; inorganic cation transmembrane transport [GO:0098662]; intracellular glucose homeostasis [GO:0001678]; memory [GO:0007613]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood-brain barrier permeability [GO:1905604]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of insulin secretion [GO:0046676]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of neuroblast migration [GO:0061855]; negative regulation of wound healing [GO:0061045]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of uterine smooth muscle relaxation [GO:1900721]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; response to insulin [GO:0032868]; response to lipopolysaccharide [GO:0032496]; response to pH [GO:0009268]; response to xenobiotic stimulus [GO:0009410]; response to zinc ion [GO:0010043]; transmembrane transport [GO:0055085]; visual learning [GO:0008542] inward rectifying potassium channel [GO:0008282]; membrane [GO:0016020]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; potassium ion-transporting ATPase complex [GO:0031004]; sarcolemma [GO:0042383]; synaptic vesicle membrane [GO:0030672] ABC-type transporter activity [GO:0140359]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-activated inward rectifier potassium channel activity [GO:0015272]; ATPase-coupled monoatomic cation transmembrane transporter activity [GO:0019829]; ATPase-coupled transmembrane transporter activity [GO:0042626]; inward rectifier potassium channel inhibitor activity [GO:0070320]; potassium channel activator activity [GO:0099104]; potassium channel activity [GO:0005267]; sulfonylurea receptor activity [GO:0008281]; transmembrane transporter binding [GO:0044325] 0.95467 -1.5194 ATEPPQGLSR 0 0 0 0 0 0 0 0 9.30672 0 0 0 0 0 0 0 9.78552 0 0 0 0 0 0 0 0 0 0 Q09472 EP300_HUMAN Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-) EP300 P300 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; B cell differentiation [GO:0030183]; behavioral defense response [GO:0002209]; cell cycle [GO:0007049]; cellular response to UV [GO:0034644]; circadian rhythm [GO:0007623]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; histone acetylation [GO:0016573]; internal peptidyl-lysine acetylation [GO:0018393]; internal protein amino acid acetylation [GO:0006475]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; learning or memory [GO:0007611]; lung development [GO:0030324]; macrophage derived foam cell differentiation [GO:0010742]; megakaryocyte development [GO:0035855]; multicellular organism growth [GO:0035264]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; peptidyl-lysine acetylation [GO:0018394]; peptidyl-lysine butyrylation [GO:0140067]; peptidyl-lysine crotonylation [GO:0140066]; peptidyl-lysine propionylation [GO:0061921]; platelet formation [GO:0030220]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1905636]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein stabilization [GO:0050821]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of cellular response to heat [GO:1900034]; regulation of glycolytic process [GO:0006110]; regulation of mitochondrion organization [GO:0010821]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tubulin deacetylation [GO:0090043]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; skeletal muscle tissue development [GO:0007519]; somitogenesis [GO:0001756]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; swimming [GO:0036268]; thigmotaxis [GO:0001966]; transcription by RNA polymerase II [GO:0006366]; transcription initiation-coupled chromatin remodeling [GO:0045815] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; histone acetyltransferase complex [GO:0000123]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; transcription regulator complex [GO:0005667] "acetyltransferase activity [GO:0016407]; acyltransferase activity [GO:0016746]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-binding transcription factor binding [GO:0140297]; enzyme activator activity [GO:0008047]; enzyme inhibitor activity [GO:0004857]; histone acetyltransferase activity [GO:0004402]; histone butyryltransferase activity [GO:0140069]; histone crotonyltransferase activity [GO:0140068]; histone H2B acetyltransferase activity [GO:0044013]; histone H3 acetyltransferase activity [GO:0010484]; histone H3K122 acetyltransferase activity [GO:0140908]; histone H4 acetyltransferase activity [GO:0010485]; histone lactyltransferase activity [GO:0120301]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; NF-kappaB binding [GO:0051059]; nuclear androgen receptor binding [GO:0050681]; nuclear receptor binding [GO:0016922]; p53 binding [GO:0002039]; peptide 2-hydroxyisobutyryltransferase activity [GO:0106226]; peptide butyryltransferase activity [GO:0140065]; peptide N-acetyltransferase activity [GO:0034212]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; pre-mRNA intronic binding [GO:0097157]; protein propionyltransferase activity [GO:0061920]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; STAT family protein binding [GO:0097677]; tau protein binding [GO:0048156]; transcription coactivator activity [GO:0003713]; transcription coactivator binding [GO:0001223]; transcription coregulator binding [GO:0001221]; zinc ion binding [GO:0008270]" 0.95446 -1.5014 AVSERIVHDYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.87573 0 0 9.84444 0 0 0 Q09666 AHNK_HUMAN Neuroblast differentiation-associated protein AHNAK (Desmoyokin) AHNAK PM227 Homo sapiens (Human) positive regulation of plasma membrane repair [GO:1905686]; regulation of RNA splicing [GO:0043484]; regulation of voltage-gated calcium channel activity [GO:1901385] actin cytoskeleton [GO:0015629]; cell-cell contact zone [GO:0044291]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; plasma membrane protein complex [GO:0098797]; sarcolemma [GO:0042383]; T-tubule [GO:0030315]; vesicle [GO:0031982] cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]; structural molecule activity conferring elasticity [GO:0097493] 0.96792 -3.7247 ADIEISGPK 15.744 15.6683 15.8019 14.1625 15.1984 14.9624 15.6419 12.3548 15.4068 15.186 9.17198 13.2072 13.4688 10.3929 10.3611 11.7848 11.0477 13.8279 12.4348 12.0758 10.5389 10.4921 10.2323 11.0493 14.1771 13.3686 11.7056 Q09FC8 ZN415_HUMAN Zinc finger protein 415 ZNF415 Homo sapiens (Human) cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; microtubule cytoskeleton [GO:0015630] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96849 -3.3242 ENLTCRRDQR 0 8.95719 0 0 0 0 0 0 0 0 0 11.011 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q09MP3 R51A2_HUMAN RAD51-associated protein 2 RAD51AP2 Homo sapiens (Human) protein-containing complex [GO:0032991] 0.96982 -4.9927 CMLYLKYPK 0 0 0 10.832 0 0 0 0 12.4288 0 0 0 0 0 0 10.6224 0 0 0 0 0 0 0 0 0 0 0 Q0D2H9 GOG8D_HUMAN Putative golgin subfamily A member 8D GOLGA8DP GOLGA8D Homo sapiens (Human) Golgi organization [GO:0007030]; spindle assembly [GO:0051225] cis-Golgi network [GO:0005801]; Golgi cis cisterna [GO:0000137]; Golgi cisterna membrane [GO:0032580] 0.88444 -0.33428 EWKLEQSMR 0 0 0 0 0 0 0 0 0 0 9.52736 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q0D2I5 IFFO1_HUMAN Non-homologous end joining factor IFFO1 (NHEJ factor IFFO1) (Intermediate filament family orphan 1) (Tumor antigen HOM-TES-103) IFFO1 IFFO Homo sapiens (Human) DNA double-strand break attachment to nuclear envelope [GO:1990683]; double-strand break repair via nonhomologous end joining [GO:0006303]; protein localization to site of double-strand break [GO:1990166] intermediate filament [GO:0005882]; nuclear inner membrane [GO:0005637]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; site of double-strand break [GO:0035861] 0.95502 -1.5198 VIKDTESLFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.44018 0 0 0 0 0 0 Q0IIM8 TBC8B_HUMAN TBC1 domain family member 8B TBC1D8B Homo sapiens (Human) activation of GTPase activity [GO:0090630]; glomerular filtration [GO:0003094]; vesicle-mediated transport [GO:0016192] cytosol [GO:0005829] calcium ion binding [GO:0005509]; GTPase activator activity [GO:0005096] 0.96709 -2.8253 DFEQLVAK 0 0 0 0 0 9.98071 0 0 0 0 9.61706 0 0 9.12977 0 0 0 0 0 0 0 0 0 0 0 0 0 Q0JRZ9 FCHO2_HUMAN F-BAR domain only protein 2 FCHO2 Homo sapiens (Human) clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; membrane invagination [GO:0010324]; protein localization to plasma membrane [GO:0072659]; synaptic vesicle endocytosis [GO:0048488] clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; presynaptic endocytic zone membrane [GO:0098835] "identical protein binding [GO:0042802]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]" 0.88523 -0.22332 ATIEEAYSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.70808 0 0 0 0 0 0 0 0 Q0P6D6 CCD15_HUMAN Coiled-coil domain-containing protein 15 CCDC15 Homo sapiens (Human) centrosome [GO:0005813] 0.96285 -2.0864 LPSSFEKWEIAR 10.893 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q0VAA2 LR74A_HUMAN Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74) LRRC74A C14orf166B LRRC74 Homo sapiens (Human) 0.88185 -0.080983 GLESNESLRVLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.90394 0 0 0 0 0 10.4019 Q0VAA5 PLCX2_HUMAN PI-PLC X domain-containing protein 2 PLCXD2 Homo sapiens (Human) lipid catabolic process [GO:0016042]; signal transduction [GO:0007165] nucleus [GO:0005634] phosphoric diester hydrolase activity [GO:0008081] 0.80137 0.23934 IQEAFGNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.8777 0 Q0VAM2 RGF1B_HUMAN Ras-GEF domain-containing family member 1B (GPI gamma-4) RASGEF1B GPIG4 Homo sapiens (Human) positive regulation of GTPase activity [GO:0043547]; Ras protein signal transduction [GO:0007265] early endosome [GO:0005769]; late endosome [GO:0005770]; midbody [GO:0030496]; plasma membrane [GO:0005886] guanyl-nucleotide exchange factor activity [GO:0005085] 0.91809 -0.86761 DIYFLNEGCANR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6121 10.2561 0 0 0 10.946 Q0VD83 APOBR_HUMAN Apolipoprotein B receptor (Apolipoprotein B-100 receptor) (Apolipoprotein B-48 receptor) (Apolipoprotein B48 receptor) (apoB-48R) APOBR APOB48R Homo sapiens (Human) cholesterol metabolic process [GO:0008203]; lipid transport [GO:0006869]; triglyceride metabolic process [GO:0006641] chylomicron [GO:0042627]; low-density lipoprotein particle [GO:0034362]; membrane [GO:0016020]; plasma membrane [GO:0005886]; very-low-density lipoprotein particle [GO:0034361] very-low-density lipoprotein particle receptor activity [GO:0030229] 0.96157 -2.5603 AGAVGPK 0 8.31102 0 0 0 0 8.20433 8.02978 0 0 9.01176 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q0VDD7 BRME1_HUMAN Break repair meiotic recombinase recruitment factor 1 (Pre-T/NK cell-associated protein 3B3) BRME1 C19orf57 Homo sapiens (Human) double-strand break repair involved in meiotic recombination [GO:1990918]; female meiosis I [GO:0007144]; spermatogenesis [GO:0007283] chromosome [GO:0005694] 0.69691 0.37857 AADGGHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.51369 0 0 0 0 0 0 0 0 0 0 0 Q0VDD8 DYH14_HUMAN Dynein axonemal heavy chain 14 (Axonemal beta dynein heavy chain 14) (Ciliary dynein heavy chain 14) DNAH14 C1orf67 Homo sapiens (Human) microtubule-based movement [GO:0007018] cilium [GO:0005929]; cytoplasm [GO:0005737]; dynein complex [GO:0030286]; microtubule [GO:0005874] ATP binding [GO:0005524]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; minus-end-directed microtubule motor activity [GO:0008569] 0.56472 0.49704 CAYIEFKEVFKK 0 10.8182 10.3172 0 0 9.36543 9.66812 10.0239 0 10.1878 10.3949 10.4665 0 0 10.212 0 0 0 0 0 0 0 0 0 10.3644 0 0 Q0VDF9 HSP7E_HUMAN Heat shock 70 kDa protein 14 (HSP70-like protein 1) (Heat shock protein HSP60) HSPA14 HSP60 HSP70L1 Homo sapiens (Human) 'de novo' cotranslational protein folding [GO:0051083]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein refolding [GO:0042026] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; heat shock protein binding [GO:0031072]; protein folding chaperone [GO:0044183] 0.87616 0.0020183 LTNSAEVAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.92214 0 0 Q0VDG4 SCRN3_HUMAN Secernin-3 SCRN3 Homo sapiens (Human) proteolysis [GO:0006508] cysteine-type exopeptidase activity [GO:0070004]; dipeptidase activity [GO:0016805] 0.93167 -1.2536 IAREHPDMR 0 9.30305 0 0 0 0 8.83058 8.9034 0 0 0 9.30186 0 0 9.53411 0 0 0 10.4613 0 0 0 0 0 0 0 8.99161 Q0VF96 CGNL1_HUMAN Cingulin-like protein 1 (Junction-associated coiled-coil protein) (Paracingulin) CGNL1 JACOP KIAA1749 Homo sapiens (Human) actin filament organization [GO:0007015]; negative regulation of small GTPase mediated signal transduction [GO:0051058]; negative regulation of stress fiber assembly [GO:0051497]; protein localization to cell-cell junction [GO:0150105] bicellular tight junction [GO:0005923]; myosin complex [GO:0016459]; protein-containing complex [GO:0032991] 0.96593 -2.7194 ATATSPDSGAK 0 0 0 0 8.81253 0 0 0 0 0 0 0 0 0 0 0 9.07502 9.5803 0 9.92466 0 0 0 0 0 10.5765 0 Q0VFX4 YL016_HUMAN Putative uncharacterized protein LOC100128554 Homo sapiens (Human) 0.63263 0.39792 LHCGPAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.23525 0 0 Q0VFZ6 CF210_HUMAN Cilia- and flagella- associated protein 210 (Coiled-coil domain-containing protein 173) CFAP210 C2orf77 CCDC173 Homo sapiens (Human) axonemal microtubule [GO:0005879] 0.96907 -4.8338 AELKTIAEYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9326 0 Q0VG06 FP100_HUMAN Fanconi anemia core complex-associated protein 100 (Fanconi anemia-associated protein of 100 kDa) FAAP100 C17orf70 Homo sapiens (Human) interstrand cross-link repair [GO:0036297]; protein monoubiquitination [GO:0006513] chromatin [GO:0000785]; cytosol [GO:0005829]; Fanconi anaemia nuclear complex [GO:0043240]; nucleoplasm [GO:0005654] DNA binding [GO:0003677] 0.96884 -3.3341 ALVTSRSAPGDPNALVK 0 0 0 0 0 0 0 0 0 8.81625 0 0 0 10.2521 0 0 0 0 0 0 8.59846 0 0 0 0 0 0 Q0VGE8 ZN816_HUMAN Zinc finger protein 816 ZNF816 ZNF816A Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.91317 -0.78638 AFTGQSTLIHHQAIHGCR 0 0 0 0 0 0 0 0 0 9.84984 0 0 0 0 13.5997 0 9.41538 0 0 0 0 0 0 0 0 0 0 Q0ZGT2 NEXN_HUMAN Nexilin (F-actin-binding protein) (Nelin) NEXN Homo sapiens (Human) axon guidance [GO:0007411]; dendrite self-avoidance [GO:0070593]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; regulation of cell migration [GO:0030334]; regulation of cytoskeleton organization [GO:0051493] actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; axon [GO:0030424]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; Z disc [GO:0030018] actin filament binding [GO:0051015]; cell-cell adhesion mediator activity [GO:0098632]; structural constituent of muscle [GO:0008307] 0.60133 0.44161 AIDLEIK 0 13.6738 9.3044 0 11.8151 0 0 0 0 13.9077 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q0ZLH3 PJVK_HUMAN Pejvakin (Autosomal recessive deafness type 59 protein) PJVK DFNB59 Homo sapiens (Human) detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; pexophagy [GO:0000425]; programmed cell death in response to reactive oxygen species [GO:0097468]; regulation of peroxisome organization [GO:1900063]; response to reactive oxygen species [GO:0000302]; sensory perception of sound [GO:0007605]; stereocilium maintenance [GO:0120045] ciliary rootlet [GO:0035253]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; peroxisomal membrane [GO:0005778]; stereocilium base [GO:0120044] 0.84984 0.11621 AVLCVVMESIRTTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6051 0 0 Q10471 GALT2_HUMAN Polypeptide N-acetylgalactosaminyltransferase 2 (EC 2.4.1.41) (Polypeptide GalNAc transferase 2) (GalNAc-T2) (pp-GaNTase 2) (Protein-UDP acetylgalactosaminyltransferase 2) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2) [Cleaved into: Polypeptide N-acetylgalactosaminyltransferase 2 soluble form] GALNT2 Homo sapiens (Human) O-glycan processing [GO:0016266]; protein maturation [GO:0051604]; protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via serine [GO:0018242]; protein O-linked glycosylation via threonine [GO:0018243] endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471] carbohydrate binding [GO:0030246]; manganese ion binding [GO:0030145]; polypeptide N-acetylgalactosaminyltransferase activity [GO:0004653] 0.6971 0.3785 DLHHSNGEEK 0 0 0 0 0 0 9.43377 10.3498 9.63205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q10472 GALT1_HUMAN Polypeptide N-acetylgalactosaminyltransferase 1 (EC 2.4.1.41) (Polypeptide GalNAc transferase 1) (GalNAc-T1) (pp-GaNTase 1) (Protein-UDP acetylgalactosaminyltransferase 1) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1) [Cleaved into: Polypeptide N-acetylgalactosaminyltransferase 1 soluble form] GALNT1 Homo sapiens (Human) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via serine [GO:0018242]; protein O-linked glycosylation via threonine [GO:0018243]; viral protein processing [GO:0019082] endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471] carbohydrate binding [GO:0030246]; manganese ion binding [GO:0030145]; polypeptide N-acetylgalactosaminyltransferase activity [GO:0004653] 0.89621 -0.54087 LTLQHVNSNQCLDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1273 0 0 0 0 0 0 0 0 0 Q10567 AP1B1_HUMAN AP-1 complex subunit beta-1 (Adaptor protein complex AP-1 subunit beta-1) (Adaptor-related protein complex 1 subunit beta-1) (Beta-1-adaptin) (Beta-adaptin 1) (Clathrin assembly protein complex 1 beta large chain) (Golgi adaptor HA1/AP1 adaptin beta subunit) AP1B1 ADTB1 BAM22 CLAPB2 Homo sapiens (Human) basolateral protein secretion [GO:0110010]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; intracellular protein transport [GO:0006886]; kidney development [GO:0001822]; melanosome assembly [GO:1903232]; platelet dense granule organization [GO:0060155]; vesicle-mediated transport [GO:0016192] AP-1 adaptor complex [GO:0030121]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; early endosome [GO:0005769]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; trans-Golgi network membrane [GO:0032588] clathrin binding [GO:0030276]; protein kinase binding [GO:0019901] 0.96422 -2.684 AELNSDKK 0 10.6819 11.0612 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q10570 CPSF1_HUMAN Cleavage and polyadenylation specificity factor subunit 1 (Cleavage and polyadenylation specificity factor 160 kDa subunit) (CPSF 160 kDa subunit) CPSF1 CPSF160 Homo sapiens (Human) mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789] mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] enzyme binding [GO:0019899]; mRNA 3'-UTR AU-rich region binding [GO:0035925] 0.11818 1.1054 EAADKEEPPSK 0 0 0 0 0 0 0 0 0 9.88864 0 0 0 0 10.1258 0 0 0 0 10.3268 0 0 0 0 10.2527 0 10.3557 Q10588 BST1_HUMAN ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 (EC 3.2.2.6) (ADP-ribosyl cyclase 2) (Bone marrow stromal cell antigen 1) (BST-1) (Cyclic ADP-ribose hydrolase 2) (cADPR hydrolase 2) (CD antigen CD157) BST1 Homo sapiens (Human) humoral immune response [GO:0006959]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell population proliferation [GO:0008284]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell-matrix adhesion [GO:0001952]; regulation of cellular extravasation [GO:0002691]; regulation of inflammatory response [GO:0050727]; regulation of integrin-mediated signaling pathway [GO:2001044]; regulation of neutrophil chemotaxis [GO:0090022]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of superoxide metabolic process [GO:0090322]; signal transduction [GO:0007165] extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; uropod [GO:0001931] "ADP-ribosyl cyclase activity [GO:0061811]; cyclic ADP-ribose hydrolase [GO:0061812]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]" 0.96024 -1.7964 ALLSPEQRNKNCTAIWEAFK 0 0 0 0 0 0 0 0 0 9.39832 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q10589 BST2_HUMAN Bone marrow stromal antigen 2 (BST-2) (HM1.24 antigen) (Tetherin) (CD antigen CD317) BST2 Homo sapiens (Human) B cell activation [GO:0042113]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of intracellular transport of viral material [GO:1901253]; negative regulation of plasmacytoid dendritic cell cytokine production [GO:0002737]; negative regulation of viral genome replication [GO:0045071]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte proliferation [GO:0070665]; regulation of actin cytoskeleton organization [GO:0032956]; response to interferon-alpha [GO:0035455]; response to interferon-beta [GO:0035456]; response to type II interferon [GO:0034341]; response to virus [GO:0009615] apical plasma membrane [GO:0016324]; azurophil granule membrane [GO:0035577]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886] identical protein binding [GO:0042802]; metalloendopeptidase inhibitor activity [GO:0008191]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723] 0.72983 0.33659 LQDASAEVER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.69902 9.30665 0 Q11130 FUT7_HUMAN "Alpha-(1,3)-fucosyltransferase 7 (EC 2.4.1.-) (Fucosyltransferase 7) (Fucosyltransferase VII) (Fuc-TVII) (FucT-VII) (Galactoside 3-L-fucosyltransferase) (Selectin ligand synthase)" FUT7 Homo sapiens (Human) "CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation [GO:0002361]; ceramide metabolic process [GO:0006672]; embryo implantation [GO:0007566]; fucosylation [GO:0036065]; inflammatory response [GO:0006954]; L-fucose catabolic process [GO:0042355]; leukocyte migration involved in immune response [GO:0002522]; leukocyte migration involved in inflammatory response [GO:0002523]; lymphocyte migration into lymph node [GO:0097022]; oligosaccharide biosynthetic process [GO:0009312]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of neutrophil migration [GO:1902624]; protein glycosylation [GO:0006486]; regulation of cell adhesion molecule production [GO:0060353]; regulation of cell-cell adhesion [GO:0022407]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of leukocyte cell-cell adhesion [GO:1903037]; regulation of leukocyte tethering or rolling [GO:1903236]; regulation of neutrophil extravasation [GO:2000389]; regulation of type IV hypersensitivity [GO:0001807]; T cell migration [GO:0072678]" Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; trans-Golgi network [GO:0005802] 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity [GO:0017083]; alpha-(1->3)-fucosyltransferase activity [GO:0046920]; fucosyltransferase activity [GO:0008417] 0.87083 0.038392 NALVAGTVPVVLGPPR 0 0 0 0 0 0 8.92107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q11203 SIAT6_HUMAN "CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase (EC 2.4.3.6) (Beta-galactoside alpha-2,3-sialyltransferase 3) (Alpha 2,3-ST 3) (Gal beta-1,3(4) GlcNAc alpha-2,3 sialyltransferase) (N-acetyllactosaminide alpha-2,3-sialyltransferase) (ST3Gal III) (ST3GalIII) (ST3N) (Sialyltransferase 6)" ST3GAL3 SIAT6 Homo sapiens (Human) ganglioside biosynthetic process via lactosylceramide [GO:0010706]; keratan sulfate biosynthetic process [GO:0018146]; O-glycan processing [GO:0016266]; oligosaccharide biosynthetic process [GO:0009312]; protein glycosylation [GO:0006486]; viral protein processing [GO:0019082] extracellular region [GO:0005576]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139] "beta-galactoside (CMP) alpha-2,3-sialyltransferase activity [GO:0003836]; N-acetyllactosaminide alpha-2,3-sialyltransferase activity [GO:0008118]; sialyltransferase activity [GO:0008373]" 0.55254 0.56 LTPALDSLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.89688 0 0 9.66374 0 0 0 0 Q11206 SIA4C_HUMAN "CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 (Alpha 2,3-ST 4) (Beta-galactoside alpha-2,3-sialyltransferase 4) (EC 2.4.3.2) (EC 2.4.3.4) (Alpha 2,3-sialyltransferase IV) (Gal-NAc6S) (Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase) (Gal-beta-1,4-GlcNAc-alpha-2,3-sialyltransferase) (N-acetyllactosaminide alpha-2,3-sialyltransferase) (EC 2.4.3.6) (SAT-3) (ST-4) (ST3Gal IV) (ST3GalIV) (ST3GalA.2) (STZ) (Sialyltransferase 4C) (SIAT4-C)" ST3GAL4 CGS23 NANTA3 SIAT4C STZ Homo sapiens (Human) cognition [GO:0050890]; glycolipid biosynthetic process [GO:0009247]; glycoprotein biosynthetic process [GO:0009101]; keratan sulfate biosynthetic process [GO:0018146]; lipid glycosylation [GO:0030259]; O-glycan processing [GO:0016266]; oligosaccharide biosynthetic process [GO:0009312]; positive regulation of blood coagulation [GO:0030194]; positive regulation of leukocyte tethering or rolling [GO:1903238]; protein glycosylation [GO:0006486]; protein sialylation [GO:1990743]; sialylation [GO:0097503]; viral protein processing [GO:0019082] extracellular region [GO:0005576]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; membrane [GO:0016020] "beta-galactoside (CMP) alpha-2,3-sialyltransferase activity [GO:0003836]; monosialoganglioside sialyltransferase activity [GO:0047288]; N-acetyllactosaminide alpha-2,3-sialyltransferase activity [GO:0008118]; neolactotetraosylceramide alpha-2,3-sialyltransferase activity [GO:0004513]; sialyltransferase activity [GO:0008373]" 0.8102 0.22491 TPSAYELPYGTK 0 0 0 0 0 0 0 0 0 9.09703 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q12756 KIF1A_HUMAN Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles) (Microtubule-based motor KIF1A) (Unc-104- and KIF1A-related protein) (hUnc-104) KIF1A ATSV C2orf20 Homo sapiens (Human) anterograde axonal transport [GO:0008089]; anterograde neuronal dense core vesicle transport [GO:1990048]; cytoskeleton-dependent intracellular transport [GO:0030705]; dense core granule cytoskeletal transport [GO:0099519]; microtubule-based movement [GO:0007018]; regulation of dendritic spine development [GO:0060998]; regulation of dendritic spine morphogenesis [GO:0061001]; retrograde neuronal dense core vesicle transport [GO:1990049]; vesicle-mediated transport [GO:0016192] axon [GO:0030424]; axon cytoplasm [GO:1904115]; dendrite [GO:0030425]; extrinsic component of neuronal dense core vesicle membrane [GO:0098674]; kinesin complex [GO:0005871]; microtubule [GO:0005874]; neuronal dense core vesicle [GO:0098992]; perinuclear region of cytoplasm [GO:0048471]; synapse [GO:0045202] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; cytoskeletal motor activity [GO:0003774]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; plus-end-directed microtubule motor activity [GO:0008574] 0.96925 -5.6519 HYLLLREK 0 12.9175 10.8227 10.4676 11.1362 11.2667 9.86231 0 0 9.65812 0 0 9.52205 12.0224 11.5267 0 12.0528 0 0 0 0 0 0 0 13.201 0 10.5772 Q12766 HMGX3_HUMAN HMG domain-containing protein 3 (HMG box-containing protein 3) (Protein SMF) HMGXB3 KIAA0194 SMF Homo sapiens (Human) nucleus [GO:0005634] DNA binding [GO:0003677] 0.89142 -0.50489 GAVVVNTEKDK 0 0 0 0 0 0 8.62611 8.80449 8.988 9.26803 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q12767 TMM94_HUMAN Transmembrane protein 94 TMEM94 KIAA0195 Homo sapiens (Human) membrane [GO:0016020] 0.80352 0.24048 QEETISIIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.6845 0 0 0 0 0 0 0 0 0 0 Q12768 WASC5_HUMAN WASH complex subunit 5 (Strumpellin) (WASH complex subunit strumpellin) WASHC5 KIAA0196 Homo sapiens (Human) actin filament polymerization [GO:0030041]; endosomal transport [GO:0016197]; endosome fission [GO:0140285]; endosome organization [GO:0007032]; lysosome organization [GO:0007040]; meiotic spindle assembly [GO:0090306]; oocyte maturation [GO:0001556]; polar body extrusion after meiotic divisions [GO:0040038]; protein transport [GO:0015031]; protein-containing complex localization [GO:0031503]; regulation of actin nucleation [GO:0051125]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315]; regulation of vesicle size [GO:0097494] cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; WASH complex [GO:0071203] 0.95228 -1.4781 DQILTDSRYNPR 0 8.91301 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.64346 10.4071 0 0 0 10.2601 0 0 0 0 0 Q12769 NU160_HUMAN Nuclear pore complex protein Nup160 (160 kDa nucleoporin) (Nucleoporin Nup160) NUP160 KIAA0197 NUP120 Homo sapiens (Human) mRNA export from nucleus [GO:0006406]; nephron development [GO:0072006]; nucleocytoplasmic transport [GO:0006913]; protein transport [GO:0015031] cytosol [GO:0005829]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nuclear pore outer ring [GO:0031080] structural constituent of nuclear pore [GO:0017056] 0.95965 -1.9476 ALQIFCR 0 0 0 0 0 0 0 0 10.1139 0 11.2611 0 0 0 0 0 0 0 9.51321 0 0 0 0 0 10.596 0 0 Q12770 SCAP_HUMAN Sterol regulatory element-binding protein cleavage-activating protein (SCAP) (SREBP cleavage-activating protein) SCAP KIAA0199 PSEC0227 Homo sapiens (Human) aging [GO:0007568]; cellular lipid metabolic process [GO:0044255]; cholesterol metabolic process [GO:0008203]; COPII-coated vesicle cargo loading [GO:0090110]; immune response [GO:0006955]; negative regulation of cholesterol biosynthetic process [GO:0045541]; positive regulation of cholesterol biosynthetic process [GO:0045542]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of fatty acid biosynthetic process [GO:0042304]; response to hypoxia [GO:0001666]; response to insulin [GO:0032868]; SREBP signaling pathway [GO:0032933] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; SREBP-SCAP complex [GO:0032936] protein-containing complex binding [GO:0044877]; sterol binding [GO:0032934]; unfolded protein binding [GO:0051082] 0.88437 -0.15945 DSPGYDFSCLVQR 0 0 0 0 0 0 0 0 0 11.4801 11.591 11.5059 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q12774 ARHG5_HUMAN Rho guanine nucleotide exchange factor 5 (Ephexin-3) (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (Transforming immortalized mammary oncogene) (p60 TIM) ARHGEF5 TIM Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; activation of GTPase activity [GO:0090630]; hematopoietic stem cell homeostasis [GO:0061484]; intracellular signal transduction [GO:0035556]; myeloid dendritic cell chemotaxis [GO:0002408]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein import [GO:1904591]; positive regulation of stress fiber assembly [GO:0051496]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cytoskeleton organization [GO:0051493]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056] anchoring junction [GO:0070161]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; podosome [GO:0002102] GTP binding [GO:0005525]; guanyl-nucleotide exchange factor activity [GO:0005085]; lipid binding [GO:0008289] 0.91185 -0.75139 EVMGGFSRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.85826 0 0 0 0 0 0 0 0 0 0 0 Q12789 TF3C1_HUMAN General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha) GTF3C1 Homo sapiens (Human) 5S class rRNA transcription by RNA polymerase III [GO:0042791]; rRNA transcription [GO:0009303]; transcription by RNA polymerase III [GO:0006383]; transcription initiation at RNA polymerase III promoter [GO:0006384]; tRNA transcription [GO:0009304]; tRNA transcription by RNA polymerase III [GO:0042797] membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; ribonucleoprotein complex [GO:1990904]; transcription factor TFIIIC complex [GO:0000127] DNA binding [GO:0003677]; RNA polymerase III general transcription initiation factor activity [GO:0000995] 0.96915 -7.4962 ALVGDFMNR 0 0 0 0 0 9.04344 0 10.0775 10.0186 0 0 9.80358 0 0 0 0 0 0 0 0 0 10.2531 9.57355 0 0 9.88148 0 Q12791 KCMA1_HUMAN "Calcium-activated potassium channel subunit alpha-1 (BK channel) (BKCA alpha) (Calcium-activated potassium channel, subfamily M subunit alpha-1) (K(VCA)alpha) (KCa1.1) (Maxi K channel) (MaxiK) (Slo-alpha) (Slo1) (Slowpoke homolog) (Slo homolog) (hSlo)" KCNMA1 KCNMA SLO Homo sapiens (Human) intracellular potassium ion homeostasis [GO:0030007]; micturition [GO:0060073]; negative regulation of cell volume [GO:0045794]; positive regulation of apoptotic process [GO:0043065]; potassium ion transport [GO:0006813]; regulation of membrane potential [GO:0042391]; regulation of monoatomic ion transmembrane transport [GO:0034765]; response to calcium ion [GO:0051592]; response to carbon monoxide [GO:0034465]; response to hypoxia [GO:0001666]; response to osmotic stress [GO:0006970]; smooth muscle contraction involved in micturition [GO:0060083] apical plasma membrane [GO:0016324]; caveola [GO:0005901]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; voltage-gated potassium channel complex [GO:0008076] actin binding [GO:0003779]; calcium-activated potassium channel activity [GO:0015269]; identical protein binding [GO:0042802]; large conductance calcium-activated potassium channel activity [GO:0060072]; metal ion binding [GO:0046872]; voltage-gated potassium channel activity [GO:0005249] 0.96375 -2.2211 EGDDAICLAELK 0 0 0 0 0 0 0 0 0 0 0 9.25153 0 0 0 9.95077 9.35515 0 0 0 0 0 0 0 0 0 0 Q12792 TWF1_HUMAN Twinfilin-1 (Protein A6) (Protein tyrosine kinase 9) TWF1 PTK9 Homo sapiens (Human) actin filament depolymerization [GO:0030042]; barbed-end actin filament capping [GO:0051016]; negative regulation of actin filament polymerization [GO:0030837]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of neuron projection development [GO:0010976]; regulation of actin phosphorylation [GO:0043538]; regulation of lamellipodium assembly [GO:0010591]; sequestering of actin monomers [GO:0042989] actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; myofibril [GO:0030016]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587] "actin binding [GO:0003779]; actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]" 0.15043 1.0198 EAFQALEK 11.3974 11.2763 11.602 0 9.42545 0 10.7782 10.9791 10.936 11.4697 0 0 10.0165 10.1746 10.0229 11.1408 10.9233 10.5872 0 0 0 8.29366 0 0 10.6978 0 0 Q12794 HYAL1_HUMAN Hyaluronidase-1 (Hyal-1) (EC 3.2.1.35) (Hyaluronoglucosaminidase-1) (Lung carcinoma protein 1) (LuCa-1) HYAL1 LUCA1 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; cartilage development [GO:0051216]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interleukin-1 [GO:0071347]; cellular response to pH [GO:0071467]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to UV-B [GO:0071493]; chondroitin sulfate catabolic process [GO:0030207]; embryonic skeletal joint morphogenesis [GO:0060272]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan biosynthetic process [GO:0030213]; hyaluronan catabolic process [GO:0030214]; hyaluronan metabolic process [GO:0030212]; inflammatory response [GO:0006954]; negative regulation of cell growth [GO:0030308]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of growth [GO:0045927]; positive regulation of hyaluranon cable assembly [GO:1900106]; response to antibiotic [GO:0046677]; response to reactive oxygen species [GO:0000302]; response to virus [GO:0009615] cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; hyaluranon cable [GO:0036117]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764] chondroitin hydrolase activity [GO:0052757]; hyaluronan synthase activity [GO:0050501]; hyalurononglucosaminidase activity [GO:0004415] 0.87075 0.05504 ALYPSIYMPAVLEGTGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7152 0 Q12796 PNRC1_HUMAN Proline-rich nuclear receptor coactivator 1 (Proline-rich protein 2) (Protein B4-2) PNRC1 PROL2 Homo sapiens (Human) "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]" nucleus [GO:0005634]; P-body [GO:0000932] 0.61143 0.42816 ENYAGAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.5509 9.02625 8.51487 0 0 0 0 0 0 0 0 0 Q12797 ASPH_HUMAN Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta-hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta-dioxygenase) ASPH BAH Homo sapiens (Human) "activation of cysteine-type endopeptidase activity [GO:0097202]; activation of store-operated calcium channel activity [GO:0032237]; calcium ion homeostasis [GO:0055074]; calcium ion transmembrane transport [GO:0070588]; cell population proliferation [GO:0008283]; cellular response to calcium ion [GO:0071277]; detection of calcium ion [GO:0005513]; face morphogenesis [GO:0060325]; limb morphogenesis [GO:0035108]; muscle contraction [GO:0006936]; negative regulation of cell population proliferation [GO:0008285]; pattern specification process [GO:0007389]; peptidyl-aspartic acid hydroxylation [GO:0042264]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of proteolysis [GO:0045862]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling [GO:0010649]; regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031585]; regulation of protein depolymerization [GO:1901879]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to ATP [GO:0033198]; roof of mouth development [GO:0060021]" calcium channel complex [GO:0034704]; cortical endoplasmic reticulum [GO:0032541]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; junctional sarcoplasmic reticulum membrane [GO:0014701]; plasma membrane [GO:0005886]; sarcoplasmic reticulum lumen [GO:0033018]; sarcoplasmic reticulum membrane [GO:0033017] calcium ion binding [GO:0005509]; electron transfer activity [GO:0009055]; peptidyl-aspartic acid 3-dioxygenase activity [GO:0062101]; structural constituent of muscle [GO:0008307]; structural molecule activity [GO:0005198]; transmembrane transporter binding [GO:0044325] 0.93197 -1.2607 YPQSPRARYGK 9.72067 9.78957 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q12802 AKP13_HUMAN A-kinase anchor protein 13 (AKAP-13) (AKAP-Lbc) (Breast cancer nuclear receptor-binding auxiliary protein) (Guanine nucleotide exchange factor Lbc) (Human thyroid-anchoring protein 31) (Lymphoid blast crisis oncogene) (LBC oncogene) (Non-oncogenic Rho GTPase-specific GTP exchange factor) (Protein kinase A-anchoring protein 13) (PRKA13) (p47) AKAP13 BRX HT31 LBC Homo sapiens (Human) adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process [GO:0086023]; adrenergic receptor signaling pathway [GO:0071875]; bone development [GO:0060348]; cardiac muscle cell differentiation [GO:0055007]; cell growth involved in cardiac muscle cell development [GO:0061049]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; nuclear export [GO:0051168]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of Rho protein signal transduction [GO:0035023]; regulation of sarcomere organization [GO:0060297]; regulation of small GTPase mediated signal transduction [GO:0051056] cell cortex [GO:0005938]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] guanyl-nucleotide exchange factor activity [GO:0005085]; MAP-kinase scaffold activity [GO:0005078]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; protein kinase A binding [GO:0051018]; small GTPase binding [GO:0031267] 0.96899 -8.3204 AETEHNK 9.13453 0 0 0 0 0 9.29845 0 0 8.49362 0 0 9.67964 0 0 0 9.74228 8.52654 0 0 9.64838 8.23261 0 0 0 0 0 Q12815 TROAP_HUMAN Tastin (Trophinin-assisting protein) (Trophinin-associated protein) TROAP Homo sapiens (Human) cell adhesion [GO:0007155] cytoplasm [GO:0005737] 0.96166 -2.5603 ETAGSSR 0 8.83194 0 0 0 0 0 0 0 0 9.57907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q12829 RB40B_HUMAN Ras-related protein Rab-40B (SOCS box-containing protein RAR) (Protein Rar) RAB40B SEC4L Homo sapiens (Human) intracellular signal transduction [GO:0035556]; protein localization to plasma membrane [GO:0072659]; protein ubiquitination [GO:0016567]; toxin transport [GO:1901998] endosome [GO:0005768]; nuclear envelope [GO:0005635]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synaptic vesicle [GO:0008021] GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.94364 -1.3372 IVLLRHGMDRLWRPSK 0 0 0 0 0 0 0 0 0 10.6468 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q12830 BPTF_HUMAN Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen) BPTF FAC1 FALZ Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; brain development [GO:0007420]; chromatin remodeling [GO:0006338]; embryonic placenta development [GO:0001892]; endoderm development [GO:0007492]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] ATPase complex [GO:1904949]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NURF complex [GO:0016589] metal ion binding [GO:0046872]; methylated histone binding [GO:0035064]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565] 0.96916 -7.5168 EQLRAEILK 0 0 0 0 0 0 0 8.21873 0 0 8.35014 0 0 0 0 0 0 0 0 0 0 0 10.1844 9.26259 10.584 0 10.7406 Q12834 CDC20_HUMAN Cell division cycle protein 20 homolog (p55CDC) CDC20 Homo sapiens (Human) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell differentiation [GO:0030154]; cell division [GO:0051301]; mitotic sister chromatid cohesion [GO:0007064]; mitotic spindle assembly [GO:0090307]; mitotic spindle assembly checkpoint signaling [GO:0007094]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; nervous system development [GO:0007399]; positive regulation of anaphase-promoting complex-dependent catabolic process [GO:1905786]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein ubiquitination [GO:0016567]; regulation of dendrite development [GO:0050773]; regulation of meiotic cell cycle [GO:0051445]; regulation of meiotic nuclear division [GO:0040020]; regulation of mitotic cell cycle [GO:0007346] anaphase-promoting complex [GO:0005680]; centrosome [GO:0005813]; cytosol [GO:0005829]; mitotic checkpoint complex [GO:0033597]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; spindle [GO:0005819]; spindle pole [GO:0000922] anaphase-promoting complex binding [GO:0010997]; histone deacetylase binding [GO:0042826]; ubiquitin ligase activator activity [GO:1990757] 0.17308 0.96661 ENQPENSQTPTK 0 0 0 0 0 0 0 0 0 0 10.5052 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.0153 Q12840 KIF5A_HUMAN Kinesin heavy chain isoform 5A (Kinesin heavy chain neuron-specific 1) (Neuronal kinesin heavy chain) (NKHC) KIF5A NKHC1 Homo sapiens (Human) anterograde axonal protein transport [GO:0099641]; anterograde dendritic transport of neurotransmitter receptor complex [GO:0098971]; axon guidance [GO:0007411]; chemical synaptic transmission [GO:0007268]; microtubule-based movement [GO:0007018]; retrograde neuronal dense core vesicle transport [GO:1990049]; synaptic vesicle transport [GO:0048489]; vesicle-mediated transport [GO:0016192] axon cytoplasm [GO:1904115]; ciliary rootlet [GO:0035253]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; kinesin complex [GO:0005871]; membrane [GO:0016020]; microtubule [GO:0005874]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; synapse [GO:0045202] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; cytoskeletal motor activity [GO:0003774]; kinesin binding [GO:0019894]; microtubule binding [GO:0008017]; plus-end-directed microtubule motor activity [GO:0008574] 0.96926 -4.4317 IAPEERQKYEEEIR 0 10.2025 0 0 0 0 0 0 0 0 10.6235 0 0 0 11.2029 0 0 0 0 0 0 9.96867 0 0 0 0 0 Q12846 STX4_HUMAN Syntaxin-4 (Renal carcinoma antigen NY-REN-31) STX4 STX4A Homo sapiens (Human) cellular response to oxidative stress [GO:0034599]; cellular response to type II interferon [GO:0071346]; cornified envelope assembly [GO:1903575]; exocytosis [GO:0006887]; intracellular protein transport [GO:0006886]; long-term synaptic potentiation [GO:0060291]; neurotransmitter transport [GO:0006836]; organelle fusion [GO:0048284]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemotaxis [GO:0050921]; positive regulation of eosinophil degranulation [GO:0043311]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to cell surface [GO:0034394]; regulation of exocytosis [GO:0017157]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; SNARE complex assembly [GO:0035493]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906] basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endomembrane system [GO:0012505]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; membrane [GO:0016020]; myelin sheath adaxonal region [GO:0035749]; neuron projection membrane [GO:0032589]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; SNARE complex [GO:0031201]; somatodendritic compartment [GO:0036477]; specific granule [GO:0042581]; storage vacuole [GO:0000322]; synapse [GO:0045202]; trans-Golgi network [GO:0005802]; vacuole [GO:0005773] SNAP receptor activity [GO:0005484]; SNARE binding [GO:0000149]; sphingomyelin phosphodiesterase activator activity [GO:0016230] 0.88823 -0.39864 NILSSADYVER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2836 0 Q12849 GRSF1_HUMAN G-rich sequence factor 1 (GRSF-1) GRSF1 Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; morphogenesis of embryonic epithelium [GO:0016331]; mRNA polyadenylation [GO:0006378]; positive regulation of mitochondrial RNA catabolic process [GO:0000962]; regulation of RNA splicing [GO:0043484]; tRNA processing [GO:0008033] cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ribonucleoprotein complex [GO:1990904]; ribonucleoprotein granule [GO:0035770] mRNA binding [GO:0003729]; RNA binding [GO:0003723] 0.84574 0.15321 SYSQESK 0 0 0 0 0 0 0 0 0 9.66711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q12851 M4K2_HUMAN Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein) MAP4K2 GCK RAB8IP Homo sapiens (Human) immune response [GO:0006955]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; protein phosphorylation [GO:0006468]; vesicle targeting [GO:0006903] basolateral plasma membrane [GO:0016323]; cytoplasm [GO:0005737]; Golgi membrane [GO:0000139] ATP binding [GO:0005524]; MAP kinase kinase kinase kinase activity [GO:0008349]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.29893 0.81276 ALLTQLLDK 0 0 0 0 9.81826 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q12857 NFIA_HUMAN Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein) NFIA KIAA1439 Homo sapiens (Human) BMP signaling pathway [GO:0030509]; cartilage development [GO:0051216]; cell morphogenesis [GO:0000902]; DNA replication [GO:0006260]; exit from mitosis [GO:0010458]; glial cell fate specification [GO:0021780]; glial cell proliferation [GO:0014009]; limb morphogenesis [GO:0035108]; neural precursor cell proliferation [GO:0061351]; neuron fate specification [GO:0048665]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; response to wounding [GO:0009611]; retina development in camera-type eye [GO:0060041]; synapse maturation [GO:0060074]; ureter development [GO:0072189]; viral genome replication [GO:0019079] cell junction [GO:0030054]; chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription factor binding [GO:0140297]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.95127 -1.3838 YHPQETLK 0 0 9.22378 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q12860 CNTN1_HUMAN Contactin-1 (Glycoprotein gp135) (Neural cell surface protein F3) CNTN1 Homo sapiens (Human) axon guidance [GO:0007411]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; central nervous system myelin formation [GO:0032289]; cerebellum development [GO:0021549]; gene expression [GO:0010467]; locomotory behavior [GO:0007626]; Notch signaling pathway [GO:0007219]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sodium ion transport [GO:0010765] axon [GO:0030424]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734] carbohydrate binding [GO:0030246]; cell-cell adhesion mediator activity [GO:0098632] 0.93206 -1.2682 AVDLIPWMEYEFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.82426 9.83202 Q12870 TCF15_HUMAN Transcription factor 15 (TCF-15) (Class A basic helix-loop-helix protein 40) (bHLHa40) (Paraxis) (Protein bHLH-EC2) TCF15 BHLHA40 BHLHEC2 Homo sapiens (Human) developmental process [GO:0032502]; ear development [GO:0043583]; establishment of epithelial cell apical/basal polarity [GO:0045198]; mesenchymal to epithelial transition [GO:0060231]; mesoderm development [GO:0007498]; muscle organ morphogenesis [GO:0048644]; negative regulation of hematopoietic stem cell differentiation [GO:1902037]; neuromuscular process controlling posture [GO:0050884]; paraxial mesoderm development [GO:0048339]; positive regulation of stem cell differentiation [GO:2000738]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; regulation of extracellular matrix organization [GO:1903053]; regulation of transcription by RNA polymerase II [GO:0006357]; respiratory system process [GO:0003016]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell population maintenance [GO:0019827] chromatin [GO:0000785]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575] "bHLH transcription factor binding [GO:0043425]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; E-box binding [GO:0070888]; protein dimerization activity [GO:0046983]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.88332 -0.12488 QPRSICTFCLSNQRK 0 0 0 0 0 0 0 0 0 0 0 9.44456 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q12872 SFSWA_HUMAN "Splicing factor, suppressor of white-apricot homolog (Splicing factor, arginine/serine-rich 8) (Suppressor of white apricot protein homolog)" SFSWAP SFRS8 SWAP Homo sapiens (Human) "alternative mRNA splicing, via spliceosome [GO:0000380]; mRNA 5'-splice site recognition [GO:0000395]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]" nucleus [GO:0005634] RNA binding [GO:0003723] 0.95965 -1.7499 ITQDLMAK 9.99435 0 7.67186 0 0 0 0 8.13504 0 0 0 0 0 0 9.61123 0 10.0887 0 0 0 0 0 0 0 0 0 0 Q12873 CHD3_HUMAN Chromodomain-helicase-DNA-binding protein 3 (CHD-3) (EC 3.6.4.12) (ATP-dependent helicase CHD3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc finger helicase) (hZFH) CHD3 Homo sapiens (Human) centrosome cycle [GO:0007098]; chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cell fate specification [GO:0042659]; regulation of DNA-templated transcription [GO:0006355]; regulation of stem cell differentiation [GO:2000736]; spindle organization [GO:0007051] centriolar satellite [GO:0034451]; centrosome [GO:0005813]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NuRD complex [GO:0016581]; PML body [GO:0016605] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent chromatin remodeler activity [GO:0140658]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; helicase activity [GO:0004386]; histone binding [GO:0042393]; RNA binding [GO:0003723]; transcription cis-regulatory region binding [GO:0000976]; zinc ion binding [GO:0008270] 0.92322 -1.1638 DSEEEFGSERDEYR 11.2047 0 11.3919 0 0 0 0 0 0 0 0 0 10.1857 0 0 8.93634 0 0 0 0 0 0 0 0 0 0 0 Q12874 SF3A3_HUMAN Splicing factor 3A subunit 3 (SF3a60) (Spliceosome-associated protein 61) (SAP 61) SF3A3 SAP61 Homo sapiens (Human) "mRNA 3'-splice site recognition [GO:0000389]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing, via transesterification reactions [GO:0000375]; U2-type prespliceosome assembly [GO:1903241]" catalytic step 2 spliceosome [GO:0071013]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2 snRNP [GO:0005686]; U2-type precatalytic spliceosome [GO:0071005]; U2-type spliceosomal complex [GO:0005684] RNA binding [GO:0003723]; zinc ion binding [GO:0008270] 0.92284 -1.0553 EEEEEEQISESESEDEENEIIYNPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3818 10.0631 10.0504 Q12882 DPYD_HUMAN Dihydropyrimidine dehydrogenase [NADP(+)] (DHPDHase) (DPD) (EC 1.3.1.2) (Dihydrothymine dehydrogenase) (Dihydrouracil dehydrogenase) DPYD Homo sapiens (Human) beta-alanine biosynthetic process [GO:0019483]; CMP catabolic process [GO:0006248]; dCMP catabolic process [GO:0006249]; dUMP catabolic process [GO:0046079]; purine nucleobase catabolic process [GO:0006145]; pyrimidine nucleobase catabolic process [GO:0006208]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; UMP catabolic process [GO:0046050]; uracil catabolic process [GO:0006212] cytoplasm [GO:0005737]; cytosol [GO:0005829] "4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]" 0.92376 -1.0701 IAELMDKK 0 0 0 0 0 0 0 0 0 0 0 0 9.49482 9.66053 9.6961 0 9.8401 0 0 0 0 0 0 0 0 0 0 Q12884 SEPR_HUMAN "Prolyl endopeptidase FAP (EC 3.4.21.26) (170 kDa melanoma membrane-bound gelatinase) (Dipeptidyl peptidase FAP) (EC 3.4.14.5) (Fibroblast activation protein alpha) (FAPalpha) (Gelatine degradation protease FAP) (EC 3.4.21.-) (Integral membrane serine protease) (Post-proline cleaving enzyme) (Serine integral membrane protease) (SIMP) (Surface-expressed protease) (Seprase) [Cleaved into: Antiplasmin-cleaving enzyme FAP, soluble form (APCE) (EC 3.4.14.5) (EC 3.4.21.-) (EC 3.4.21.26)]" FAP Homo sapiens (Human) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; melanocyte apoptotic process [GO:1902362]; melanocyte proliferation [GO:0097325]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of extracellular matrix organization [GO:1903054]; positive regulation of execution phase of apoptosis [GO:1900119]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of cell cycle [GO:0051726]; regulation of collagen catabolic process [GO:0010710]; regulation of fibrinolysis [GO:0051917] apical part of cell [GO:0045177]; basal part of cell [GO:0045178]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane [GO:0016020]; peptidase complex [GO:1905368]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587] dipeptidyl-peptidase activity [GO:0008239]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activity [GO:0008233]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236] 0.60566 0.43653 FIEMGFIDEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.7084 0 0 0 0 0 12.3502 0 0 Q12888 TP53B_HUMAN TP53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1) TP53BP1 Homo sapiens (Human) cellular response to X-ray [GO:0071481]; DNA damage checkpoint signaling [GO:0000077]; DNA damage response [GO:0006974]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of isotype switching [GO:0045830]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein homooligomerization [GO:0051260] "chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; DNA repair complex [GO:1990391]; kinetochore [GO:0000776]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]" damaged DNA binding [GO:0003684]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; p53 binding [GO:0002039]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; telomeric DNA binding [GO:0042162]; transcription coregulator activity [GO:0003712]; ubiquitin modification-dependent histone binding [GO:0061649] 0.9644 -2.267 EQNPPPARSEDMPFSPK 9.43833 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.37675 0 0 0 0 Q12889 OVGP1_HUMAN Oviduct-specific glycoprotein (Estrogen-dependent oviduct protein) (Mucin-9) (Oviductal glycoprotein) (Oviductin) OVGP1 MUC9 OGP Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; chitin catabolic process [GO:0006032]; female pregnancy [GO:0007565]; negative regulation of binding of sperm to zona pellucida [GO:2000360]; single fertilization [GO:0007338] cytosol [GO:0005829]; egg coat [GO:0035805]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; microtubule cytoskeleton [GO:0015630]; perivitelline space [GO:0098595]; transport vesicle [GO:0030133] chitin binding [GO:0008061]; chitinase activity [GO:0004568] 0.88419 -0.16821 GTTVTPTK 0 0 0 0 0 0 0 0 0 0 0 10.5229 0 0 0 0 0 0 0 0 8.89875 0 0 0 0 0 9.30453 Q12899 TRI26_HUMAN Tripartite motif-containing protein 26 (EC 2.3.2.27) (Acid finger protein) (AFP) (RING finger protein 95) (Zinc finger protein 173) TRIM26 RNF95 ZNF173 Homo sapiens (Human) innate immune response [GO:0045087]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; protein ubiquitination [GO:0016567]; suppression of viral release by host [GO:0044790] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.67788 0.39371 GVGELAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15.0424 0 0 0 0 0 0 14.8194 0 14.6616 Q12901 ZN155_HUMAN Zinc finger protein 155 ZNF155 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.93908 -1.2963 LVHRTYRK 0 0 0 0 0 0 0 0 0 0 12.8039 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q12904 AIMP1_HUMAN Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (Multisynthase complex auxiliary component p43) [Cleaved into: Endothelial monocyte-activating polypeptide 2 (EMAP-2) (Endothelial monocyte-activating polypeptide II) (EMAP-II) (Small inducible cytokine subfamily E member 1)] AIMP1 EMAP2 SCYE1 Homo sapiens (Human) angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of glucagon secretion [GO:0070094]; translation [GO:0006412] aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cell surface [GO:0009986]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleus [GO:0005634] cytokine activity [GO:0005125]; GTPase binding [GO:0051020]; protein homodimerization activity [GO:0042803]; tRNA binding [GO:0000049] 0.86134 0.094242 MVILLCNLKPAKMR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.81543 0 0 0 0 0 0 0 0 Q12905 ILF2_HUMAN Interleukin enhancer-binding factor 2 (Nuclear factor of activated T-cells 45 kDa) ILF2 NF45 PRO3063 Homo sapiens (Human) positive regulation of DNA-templated transcription [GO:0045893] extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724] DNA binding [GO:0003677]; double-stranded RNA binding [GO:0003725]; RNA binding [GO:0003723] 0 13.688 ILITTVPPNLR 0 0 0 0 0 0 0 0 0 9.02937 0 0 0 0 0 0 0 0 0 11.6051 11.1833 10.6188 0 10.478 11.8767 11.6465 11.3768 Q12906 ILF3_HUMAN Interleukin enhancer-binding factor 3 (Double-stranded RNA-binding protein 76) (DRBP76) (M-phase phosphoprotein 4) (MPP4) (Nuclear factor associated with dsRNA) (NFAR) (Nuclear factor of activated T-cells 90 kDa) (NF-AT-90) (Translational control protein 80) (TCP80) ILF3 DRBF MPHOSPH4 NF90 Homo sapiens (Human) defense response to virus [GO:0051607]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of translation [GO:0017148]; negative regulation of viral genome replication [GO:0045071]; positive regulation of DNA-templated transcription [GO:0045893]; protein phosphorylation [GO:0006468] cytoplasm [GO:0005737]; extracellular region [GO:0005576]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] DNA binding [GO:0003677]; double-stranded RNA binding [GO:0003725]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]; virus receptor activity [GO:0001618] 0.0083565 2.2079 AVSDWIDEQEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.24048 0 9.83848 9.06604 0 9.27647 0 0 0 0 10.7883 0 10.9004 Q12907 LMAN2_HUMAN Vesicular integral-membrane protein VIP36 (Glycoprotein GP36b) (Lectin mannose-binding 2) (Vesicular integral-membrane protein 36) (VIP36) LMAN2 C5orf8 Homo sapiens (Human) "endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of phagocytosis [GO:0050766]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]" cell surface [GO:0009986]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886] carbohydrate binding [GO:0030246]; heat shock protein binding [GO:0031072]; mannose binding [GO:0005537]; metal ion binding [GO:0046872] 0.35679 0.75536 DNVDDPTGNFR 0 0 0 0 0 0 8.70134 0 0 0 0 0 10.5645 0 0 0 0 0 11.1572 0 0 0 0 0 0 9.65157 0 Q12912 IRAG2_HUMAN "Inositol 1,4,5-triphosphate receptor associated 2 (Lymphoid-restricted membrane protein) (Protein Jaw1) [Cleaved into: Processed inositol 1,4,5-triphosphate receptor associated 2]" IRAG2 JAW1 LRMP Homo sapiens (Human) immune system process [GO:0002376]; nucleus organization [GO:0006997]; single fertilization [GO:0007338]; vesicle fusion [GO:0006906]; vesicle targeting [GO:0006903] azurophil granule membrane [GO:0035577]; chromosome [GO:0005694]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]; spindle pole [GO:0000922] microtubule binding [GO:0008017] 0.1969 0.92695 HNGPPPV 14.3363 14.2759 14.3987 11.7682 11.6133 11.5553 14.4425 14.4437 14.3855 14.2223 14.5702 14.4132 11.6107 11.857 12.346 12.4347 12.2246 12.9248 0 11.0627 9.8304 10.7169 10.3982 10.5859 12.402 13.0267 0 Q12913 PTPRJ_HUMAN Receptor-type tyrosine-protein phosphatase eta (Protein-tyrosine phosphatase eta) (R-PTP-eta) (EC 3.1.3.48) (Density-enhanced phosphatase 1) (DEP-1) (HPTP eta) (Protein-tyrosine phosphatase receptor type J) (R-PTP-J) (CD antigen CD148) PTPRJ DEP1 Homo sapiens (Human) B cell differentiation [GO:0030183]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; contact inhibition [GO:0060242]; cytokine-mediated signaling pathway [GO:0019221]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of vascular permeability [GO:0043116]; peptidyl-tyrosine dephosphorylation [GO:0035335]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of cell adhesion [GO:0045785]; positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [GO:1905451]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor production [GO:0032760]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; T cell receptor signaling pathway [GO:0050852] cell surface [GO:0009986]; cell-cell junction [GO:0005911]; extracellular exosome [GO:0070062]; immunological synapse [GO:0001772]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; specific granule membrane [GO:0035579] beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; delta-catenin binding [GO:0070097]; gamma-catenin binding [GO:0045295]; mitogen-activated protein kinase binding [GO:0051019]; phosphatase activity [GO:0016791]; platelet-derived growth factor receptor binding [GO:0005161]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725] 0.95436 -1.5337 NRYNNVLPYDISR 0 0 0 0 0 0 0 0 0 0 0 8.91913 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5866 0 Q12923 PTN13_HUMAN Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1) PTPN13 PNP1 PTP1E PTPL1 Homo sapiens (Human) cellular response to toxic substance [GO:0097237]; negative regulation of excitatory synapse assembly [GO:1904890]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein tyrosine phosphatase activity [GO:0004725] 0.96864 -7.813 ASWEEKPREMSK 0 0 0 0 9.21123 0 0 8.79756 0 0 0 10.2303 0 0 0 0 9.58976 0 0 0 0 0 0 0 0 0 0 Q12929 EPS8_HUMAN Epidermal growth factor receptor kinase substrate 8 EPS8 Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin filament bundle assembly [GO:0051017]; actin polymerization-dependent cell motility [GO:0070358]; adult locomotory behavior [GO:0008344]; barbed-end actin filament capping [GO:0051016]; behavioral response to ethanol [GO:0048149]; cellular response to leukemia inhibitory factor [GO:1990830]; dendritic cell migration [GO:0036336]; exit from mitosis [GO:0010458]; positive regulation of ruffle assembly [GO:1900029]; Rac protein signal transduction [GO:0016601]; regulation of actin filament length [GO:0030832]; regulation of cell shape [GO:0008360]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; regulation of Rho protein signal transduction [GO:0035023]; Rho protein signal transduction [GO:0007266] brush border [GO:0005903]; cell cortex [GO:0005938]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; NMDA selective glutamate receptor complex [GO:0017146]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; ruffle membrane [GO:0032587]; stereocilium [GO:0032420]; stereocilium tip [GO:0032426]; vesicle [GO:0031982] actin binding [GO:0003779]; small GTPase binding [GO:0031267] 0.95424 -1.5025 NYEPLKTQPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2417 0 0 0 0 0 0 0 0 0 0 Q12931 TRAP1_HUMAN "Heat shock protein 75 kDa, mitochondrial (HSP 75) (TNFR-associated protein 1) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1)" TRAP1 HSP75 Homo sapiens (Human) chaperone-mediated protein folding [GO:0061077]; negative regulation of cellular respiration [GO:1901856]; negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide [GO:1903751]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; protein folding [GO:0006457]; translational attenuation [GO:0009386] cell periphery [GO:0071944]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; tumor necrosis factor receptor binding [GO:0005164]; unfolded protein binding [GO:0051082] 0.19285 0.92952 ELISNASDALEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1716 0 10.4907 0 0 0 0 0 9.74302 Q12933 TRAF2_HUMAN TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3) TRAF2 TRAP3 Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular response to nitric oxide [GO:0071732]; innate immune response [GO:0045087]; interleukin-17-mediated signaling pathway [GO:0097400]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; mRNA stabilization [GO:0048255]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of immunoglobulin production [GO:0002637]; regulation of protein-containing complex assembly [GO:0043254]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; signal transduction involved in regulation of gene expression [GO:0023019]; tumor necrosis factor-mediated signaling pathway [GO:0033209] CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IRE1-TRAF2-ASK1 complex [GO:1990604]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; TRAF2-GSTP1 complex [GO:0097057]; tumor necrosis factor receptor superfamily complex [GO:0002947]; ubiquitin ligase complex [GO:0000151]; vesicle membrane [GO:0012506] CD40 receptor binding [GO:0005174]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; molecular adaptor activity [GO:0060090]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; protein-macromolecule adaptor activity [GO:0030674]; sphingolipid binding [GO:0046625]; thioesterase binding [GO:0031996]; tumor necrosis factor binding [GO:0043120]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.84064 0.14352 CPLMLTECPACK 0 0 0 0 8.81186 9.36293 0 11.4019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q12934 BFSP1_HUMAN Filensin (Beaded filament structural protein 1) (Lens fiber cell beaded-filament structural protein CP 115) (CP115) (Lens intermediate filament-like heavy) (LIFL-H) [Cleaved into: Filensin C-terminal fragment; Filensin N-terminal fragment] BFSP1 Homo sapiens (Human) cell maturation [GO:0048469]; intermediate filament organization [GO:0045109]; lens fiber cell development [GO:0070307] cell cortex [GO:0005938]; cytoplasm [GO:0005737]; intermediate filament [GO:0005882]; plasma membrane [GO:0005886] structural constituent of cytoskeleton [GO:0005200]; structural constituent of eye lens [GO:0005212] 0.96431 -2.2651 EIEETERVLEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.6288 0 0 0 0 0 0 0 0 0 Q12947 FOXF2_HUMAN Forkhead box protein F2 (Forkhead-related activator 2) (FREAC-2) (Forkhead-related protein FKHL6) (Forkhead-related transcription factor 2) FOXF2 FKHL6 FREAC2 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digestive tract development [GO:0048566]; epithelial to mesenchymal transition [GO:0001837]; establishment of planar polarity of embryonic epithelium [GO:0042249]; extracellular matrix organization [GO:0030198]; genitalia development [GO:0048806]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; regulation of protein polyubiquitination [GO:1902914]; regulation of transcription by RNA polymerase II [GO:0006357]; roof of mouth development [GO:0060021] chromatin [GO:0000785]; intracellular membrane-bounded organelle [GO:0043231]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; general transcription initiation factor binding [GO:0140296]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; TFIIB-class transcription factor binding [GO:0001093]" 0.95426 -1.5125 FPFFRGAYQGWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.26688 0 0 0 0 Q12955 ANK3_HUMAN Ankyrin-3 (ANK-3) (Ankyrin-G) ANK3 Homo sapiens (Human) axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165] axon initial segment [GO:0043194]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; costamere [GO:0043034]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; intercalated disc [GO:0014704]; lateral plasma membrane [GO:0016328]; lysosome [GO:0005764]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; node of Ranvier [GO:0033268]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; sarcolemma [GO:0042383]; sarcoplasmic reticulum [GO:0016529]; spectrin-associated cytoskeleton [GO:0014731]; T-tubule [GO:0030315]; Z disc [GO:0030018] cadherin binding [GO:0045296]; cytoskeletal anchor activity [GO:0008093]; cytoskeletal protein binding [GO:0008092]; protein-macromolecule adaptor activity [GO:0030674]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]; transmembrane transporter binding [GO:0044325] 0.96873 -7.9813 APAVTEATPLK 8.2096 11.437 11.469 10.0015 8.90427 9.08058 11.3193 11.4771 0 10.8981 11.7974 11.9676 0 0 9.95636 0 0 0 0 0 0 0 0 10.2419 0 0 0 Q12959 DLG1_HUMAN Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg) DLG1 Homo sapiens (Human) actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; activation of protein kinase activity [GO:0032147]; amyloid precursor protein metabolic process [GO:0042982]; astral microtubule organization [GO:0030953]; bicellular tight junction assembly [GO:0070830]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; cortical microtubule organization [GO:0043622]; embryonic skeletal system morphogenesis [GO:0048704]; endothelial cell proliferation [GO:0001935]; establishment of centrosome localization [GO:0051660]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; hard palate development [GO:0060022]; immunological synapse formation [GO:0001771]; lens development in camera-type eye [GO:0002088]; membrane raft organization [GO:0031579]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; peristalsis [GO:0030432]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; protein-containing complex localization [GO:0031503]; regulation of cell shape [GO:0008360]; regulation of membrane potential [GO:0042391]; regulation of myelination [GO:0031641]; regulation of potassium ion export across plasma membrane [GO:1903764]; regulation of potassium ion import [GO:1903286]; regulation of protein localization to synapse [GO:1902473]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1903760]; reproductive structure development [GO:0048608]; smooth muscle tissue development [GO:0048745]; T cell proliferation [GO:0042098] adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cell projection membrane [GO:0031253]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; immunological synapse [GO:0001772]; intercalated disc [GO:0014704]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; membrane raft [GO:0045121]; microtubule [GO:0005874]; MPP7-DLG1-LIN7 complex [GO:0097025]; myelin sheath abaxonal region [GO:0035748]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; node of Ranvier [GO:0033268]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; sarcolemma [GO:0042383]; synaptic membrane [GO:0097060] cadherin binding [GO:0045296]; cytoskeletal protein binding [GO:0008092]; guanylate kinase activity [GO:0004385]; kinase binding [GO:0019900]; L27 domain binding [GO:0097016]; molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902]; phosphoprotein phosphatase activity [GO:0004721]; potassium channel regulator activity [GO:0015459]; structural constituent of postsynaptic density [GO:0098919]; transmembrane transporter binding [GO:0044325] 0.96193 -2.0469 LSQTEDRQLR 0 0 0 0 0 0 9.36562 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q12962 TAF10_HUMAN Transcription initiation factor TFIID subunit 10 (STAF28) (Transcription initiation factor TFIID 30 kDa subunit) (TAF(II)30) (TAFII-30) (TAFII30) TAF10 TAF2A TAF2H TAFII30 Homo sapiens (Human) allantois development [GO:1905069]; apoptotic process [GO:0006915]; chromatin remodeling [GO:0006338]; DNA-templated transcription initiation [GO:0006352]; embryonic placenta development [GO:0001892]; G1/S transition of mitotic cell cycle [GO:0000082]; hepatocyte differentiation [GO:0070365]; histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; lateral mesodermal cell differentiation [GO:0048371]; limb development [GO:0060173]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; mRNA transcription by RNA polymerase II [GO:0042789]; multicellular organism growth [GO:0035264]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; protein phosphorylation [GO:0006468]; regulation of DNA binding [GO:0051101]; regulation of DNA repair [GO:0006282]; regulation of DNA-templated transcription [GO:0006355]; regulation of RNA splicing [GO:0043484]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA polymerase II preinitiation complex assembly [GO:0051123]; SAGA complex assembly [GO:0036285]; somitogenesis [GO:0001756]; transcription by RNA polymerase II [GO:0006366]; transcription initiation at RNA polymerase II promoter [GO:0006367] cytoplasm [GO:0005737]; male germ cell nucleus [GO:0001673]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; SAGA complex [GO:0000124]; transcription factor TFIID complex [GO:0005669]; transcription factor TFTC complex [GO:0033276]; transcription preinitiation complex [GO:0097550] DNA binding [GO:0003677]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; nuclear estrogen receptor binding [GO:0030331]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase binding [GO:0070063]; RNA polymerase II general transcription initiation factor activity [GO:0016251] 0.9535 -1.4877 GTASGSSRSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.31667 Q12965 MYO1E_HUMAN Unconventional myosin-Ie (Myosin-Ic) (Unconventional myosin 1E) MYO1E MYO1C Homo sapiens (Human) actin filament organization [GO:0007015]; endocytosis [GO:0006897]; glomerular basement membrane development [GO:0032836]; glomerular filtration [GO:0003094]; in utero embryonic development [GO:0001701]; nitrogen compound metabolic process [GO:0006807]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; podocyte development [GO:0072015]; post-embryonic hemopoiesis [GO:0035166]; vasculogenesis [GO:0001570]; vesicle transport along actin filament [GO:0030050] actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; brush border [GO:0005903]; clathrin-coated vesicle [GO:0030136]; cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; extracellular exosome [GO:0070062]; myosin complex [GO:0016459]; vesicle [GO:0031982] actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; calmodulin binding [GO:0005516]; cytoskeletal motor activity [GO:0003774]; phosphatidylinositol binding [GO:0035091] 0.40924 0.69442 IVCDLIENK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.00904 0 0 0 0 0 0 9.67419 0 0 0 0 0 0 Q12968 NFAC3_HUMAN "Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (NFATx) (T-cell transcription factor NFAT4) (NF-AT4) (NF-AT4c)" NFATC3 NFAT4 Homo sapiens (Human) calcineurin-NFAT signaling cascade [GO:0033173]; inflammatory response [GO:0006954]; negative regulation of miRNA transcription [GO:1902894]; negative regulation of vascular associated smooth muscle cell differentiation [GO:1905064]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.72161 0.36316 DMSQISVSQGAGVSR 0 0 0 0 0 0 0 0 0 10.9349 0 0 0 0 0 0 0 0 0 0 0 9.12151 0 0 0 0 0 Q12979 ABR_HUMAN Active breakpoint cluster region-related protein ABR Homo sapiens (Human) activation of GTPase activity [GO:0090630]; modulation of chemical synaptic transmission [GO:0050804]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264] axon [GO:0030424]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Schaffer collateral - CA1 synapse [GO:0098685] GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085] 0.88436 -0.13372 HQQYDCK 0 0 8.67175 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.67025 0 0 0 0 0 0 0 0 0 Q12980 NPRL3_HUMAN GATOR complex protein NPRL3 (-14 gene protein) (Alpha-globin regulatory element-containing gene protein) (Nitrogen permease regulator 3-like protein) (Protein CGTHBA) NPRL3 C16orf35 CGTHBA MARE Homo sapiens (Human) aorta morphogenesis [GO:0035909]; cardiac muscle tissue development [GO:0048738]; cellular response to amino acid starvation [GO:0034198]; negative regulation of TOR signaling [GO:0032007]; negative regulation of TORC1 signaling [GO:1904262]; positive regulation of autophagy [GO:0010508]; roof of mouth development [GO:0060021]; TORC1 signaling [GO:0038202]; ventricular septum development [GO:0003281] GATOR1 complex [GO:1990130]; lysosomal membrane [GO:0005765] GTPase activator activity [GO:0005096] 0.80927 0.23219 AIRPYHALLLLSDEK 0 0 11.2243 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q12983 BNIP3_HUMAN BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 BNIP3 NIP3 Homo sapiens (Human) autophagic cell death [GO:0048102]; autophagy of mitochondrion [GO:0000422]; brown fat cell differentiation [GO:0050873]; cardiac muscle cell apoptotic process [GO:0010659]; cellular response to cobalt ion [GO:0071279]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to mechanical stimulus [GO:0071260]; cerebral cortex development [GO:0021987]; defense response to virus [GO:0051607]; granzyme-mediated programmed cell death signaling pathway [GO:0140507]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrial outer membrane permeabilization [GO:0097345]; mitochondrial protein catabolic process [GO:0035694]; negative regulation of apoptotic process [GO:0043066]; negative regulation of membrane potential [GO:0045837]; negative regulation of mitochondrial fusion [GO:0010637]; negative regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902109]; negative regulation of mitochondrial membrane potential [GO:0010917]; negative regulation of programmed cell death [GO:0043069]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; neuron apoptotic process [GO:0051402]; oligodendrocyte differentiation [GO:0048709]; positive regulation of apoptotic process [GO:0043065]; positive regulation of autophagy [GO:0010508]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of macroautophagy [GO:0016239]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of necrotic cell death [GO:0010940]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein-containing complex disassembly [GO:0043243]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; reactive oxygen species metabolic process [GO:0072593]; regulation of aerobic respiration [GO:1903715]; regulation of mitochondrial membrane permeability [GO:0046902]; response to axon injury [GO:0048678]; response to bacterium [GO:0009617]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to oxygen-glucose deprivation [GO:0090649]; toxin transport [GO:1901998] cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; mitochondrial membrane [GO:0031966]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic density [GO:0014069] GTPase binding [GO:0051020]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803] 0.90976 -0.74471 HPKRTATLSMR 0 0 0 0 0 0 0 0 0 10.1706 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q12986 NFX1_HUMAN "Transcriptional repressor NF-X1 (EC 2.3.2.-) (Nuclear transcription factor, X box-binding protein 1)" NFX1 NFX2 Homo sapiens (Human) inflammatory response [GO:0006954]; negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; transcription by RNA polymerase II [GO:0006366] chromatin [GO:0000785]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA binding [GO:0003723]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270]" 0.95494 -1.6276 EHSPSESEK 11.57 11.9849 11.895 0 10.2166 10.0949 12.1227 12.6307 11.9732 9.11301 12.1775 11.2451 0 0 0 10.0934 0 0 8.41642 0 0 10.5142 0 9.05861 0 0 0 Q12996 CSTF3_HUMAN Cleavage stimulation factor subunit 3 (CF-1 77 kDa subunit) (Cleavage stimulation factor 77 kDa subunit) (CSTF 77 kDa subunit) (CstF-77) CSTF3 Homo sapiens (Human) mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378]; RNA 3'-end processing [GO:0031123] nucleoplasm [GO:0005654]; nucleus [GO:0005634] mRNA binding [GO:0003729]; RNA binding [GO:0003723] 0.96949 -4.0456 ALGYKDVSR 0 9.41365 0 0 0 0 0 0 0 0 0 0 0 0 0 9.79476 0 0 0 0 0 0 0 0 0 0 0 Q13002 GRIK2_HUMAN "Glutamate receptor ionotropic, kainate 2 (GluK2) (Excitatory amino acid receptor 4) (EAA4) (Glutamate receptor 6) (GluR-6) (GluR6)" GRIK2 GLUR6 Homo sapiens (Human) "behavioral fear response [GO:0001662]; chemical synaptic transmission [GO:0007268]; detection of cold stimulus involved in thermoception [GO:0120169]; glutamate receptor signaling pathway [GO:0007215]; inhibitory postsynaptic potential [GO:0060080]; intracellular calcium ion homeostasis [GO:0006874]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of synaptic transmission [GO:0050806]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]" glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; kainate selective glutamate receptor complex [GO:0032983]; mossy fiber rosette [GO:0097471]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; presynaptic membrane [GO:0042734] extracellularly glutamate-gated ion channel activity [GO:0005234]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315] 0.84722 0.16816 ELSTILGFTYEIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.66924 0 0 0 0 0 0 Q13003 GRIK3_HUMAN "Glutamate receptor ionotropic, kainate 3 (GluK3) (Excitatory amino acid receptor 5) (EAA5) (Glutamate receptor 7) (GluR-7) (GluR7)" GRIK3 GLUR7 Homo sapiens (Human) "G protein-coupled glutamate receptor signaling pathway [GO:0007216]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; synaptic transmission, glutamatergic [GO:0035249]" axon [GO:0030424]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; presynaptic membrane [GO:0042734]; terminal bouton [GO:0043195] adenylate cyclase inhibiting G protein-coupled glutamate receptor activity [GO:0001640]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315] 0.9146 -0.81701 VGVWSPADGLNITEVAKGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3206 0 0 Q13009 TIAM1_HUMAN Rho guanine nucleotide exchange factor TIAM1 (T-lymphoma invasion and metastasis-inducing protein 1) (TIAM-1) TIAM1 Homo sapiens (Human) "activation of GTPase activity [GO:0090630]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; ephrin receptor signaling pathway [GO:0048013]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of protein binding [GO:0032092]; protein-containing complex assembly [GO:0065003]; Rac protein signal transduction [GO:0016601]; regulation of dopaminergic neuron differentiation [GO:1904338]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of non-canonical Wnt signaling pathway [GO:2000050]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" cell-cell contact zone [GO:0044291]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; plasma membrane [GO:0005886]; synapse [GO:0045202] guanyl-nucleotide exchange factor activity [GO:0005085]; kinase binding [GO:0019900]; lipid binding [GO:0008289] 0.96538 -2.2908 AVSAPSKSLGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.20149 0 0 0 0 0 9.32773 0 0 Q13011 ECH1_HUMAN "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (EC 5.3.3.-)" ECH1 Homo sapiens (Human) fatty acid beta-oxidation [GO:0006635] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777] "delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity [GO:0051750]" 0.035165 1.5257 AVVISGAGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.59472 9.63715 0 Q13017 RHG05_HUMAN Rho GTPase-activating protein 5 (Rho-type GTPase-activating protein 5) (p190-B) ARHGAP5 RHOGAP5 Homo sapiens (Human) cell adhesion [GO:0007155]; mammary gland development [GO:0030879]; regulation of cell size [GO:0008361]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; plasma membrane [GO:0005886] GTP binding [GO:0005525]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; SH2 domain binding [GO:0042169] 0.92268 -1.1589 DYHATWKTVSNK 0 0 0 0 10.2003 9.93653 0 9.67315 0 10.3129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.51124 10.3289 Q13018 PLA2R_HUMAN Secretory phospholipase A2 receptor (PLA2-R) (PLA2R) (180 kDa secretory phospholipase A2 receptor) (C-type lectin domain family 13 member C) (M-type receptor) [Cleaved into: Soluble secretory phospholipase A2 receptor (Soluble PLA2-R) (Soluble PLA2R)] PLA2R1 CLEC13C Homo sapiens (Human) "negative regulation of arachidonic acid secretion [GO:1900139]; negative regulation of phospholipase A2 activity [GO:1900138]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of cytokine production [GO:0001819]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; positive regulation of podocyte apoptotic process [GO:1904635]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; replicative senescence [GO:0090399]" cell surface [GO:0009986]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] carbohydrate binding [GO:0030246]; phospholipase binding [GO:0043274]; signaling receptor activity [GO:0038023] 0.92213 -1.1038 LLEWQDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.58871 Q13023 AKAP6_HUMAN A-kinase anchor protein 6 (AKAP-6) (A-kinase anchor protein 100 kDa) (AKAP 100) (Protein kinase A-anchoring protein 6) (PRKA6) (mAKAP) AKAP6 AKAP100 KIAA0311 Homo sapiens (Human) action potential [GO:0001508]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to cytokine stimulus [GO:0071345]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell growth [GO:0030307]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of delayed rectifier potassium channel activity [GO:1902261]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; protein targeting [GO:0006605]; regulation of membrane repolarization [GO:0060306]; regulation of protein kinase A signaling [GO:0010738]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880] calcium channel complex [GO:0034704]; caveola [GO:0005901]; cytoplasm [GO:0005737]; intercalated disc [GO:0014704]; junctional sarcoplasmic reticulum membrane [GO:0014701]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; sarcoplasmic reticulum [GO:0016529]; T-tubule [GO:0030315] adenylate cyclase binding [GO:0008179]; molecular adaptor activity [GO:0060090]; protein kinase A binding [GO:0051018]; protein kinase A regulatory subunit binding [GO:0034237]; protein-membrane adaptor activity [GO:0043495]; transmembrane transporter binding [GO:0044325] 0.92423 -1.0528 DLTYSVQQDSDSK 0 8.57312 0 0 10.3597 0 0 14.1653 0 0 8.4005 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13029 PRDM2_HUMAN PR domain zinc finger protein 2 (EC 2.1.1.355) (GATA-3-binding protein G3B) (Lysine N-methyltransferase 8) (MTB-ZF) (MTE-binding protein) (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc finger protein) (Zinc finger protein RIZ) PRDM2 KMT8 RIZ Homo sapiens (Human) determination of adult lifespan [GO:0008340]; histone methylation [GO:0016571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; histone H3K9 trimethyltransferase activity [GO:0140949]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]" 0.96945 -4.7959 ETVSPPCFDEYK 0 0 0 0 0 9.13681 0 0 0 0 0 0 0 0 11.2804 0 0 0 0 0 0 0 0 0 9.77373 0 0 Q13033 STRN3_HUMAN Striatin-3 (Cell cycle autoantigen SG2NA) (S/G2 antigen) STRN3 GS2NA SG2NA Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to estradiol [GO:0032355] cytoplasm [GO:0005737]; dendrite [GO:0030425]; FAR/SIN/STRIPAK complex [GO:0090443]; Golgi apparatus [GO:0005794]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] armadillo repeat domain binding [GO:0070016]; calmodulin binding [GO:0005516]; protein phosphatase 2A binding [GO:0051721]; protein-containing complex binding [GO:0044877]; small GTPase binding [GO:0031267] 0.83739 0.19315 LWNPQEK 9.14254 0 0 0 0 0 0 0 8.75255 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13042 CDC16_HUMAN Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6) CDC16 ANAPC6 Homo sapiens (Human) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell cycle [GO:0007049]; cell division [GO:0051301]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; protein K11-linked ubiquitination [GO:0070979]; regulation of meiotic cell cycle [GO:0051445]; regulation of mitotic cell cycle [GO:0007346] anaphase-promoting complex [GO:0005680]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitotic spindle [GO:0072686]; nucleoplasm [GO:0005654] 0.87416 0.035778 NIISPPWDFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.47005 0 0 0 0 0 0 0 0 Q13045 FLII_HUMAN Protein flightless-1 homolog FLII FLIL Homo sapiens (Human) actin filament severing [GO:0051014]; actin polymerization or depolymerization [GO:0008154]; barbed-end actin filament capping [GO:0051016]; myofibril assembly [GO:0030239] actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; centriolar satellite [GO:0034451]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "actin binding [GO:0003779]; actin filament binding [GO:0051015]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]" 0.95527 -1.6329 GVDLSGNDFK 0 0 0 0 0 0 0 0 0 11.6487 0 0 0 0 10.5632 0 0 0 0 0 0 0 0 0 11.8572 0 0 Q13057 COASY_HUMAN Bifunctional coenzyme A synthase (CoA synthase) (NBP) (POV-2) [Includes: Phosphopantetheine adenylyltransferase (EC 2.7.7.3) (Dephospho-CoA pyrophosphorylase) (Pantetheine-phosphate adenylyltransferase) (PPAT); Dephospho-CoA kinase (DPCK) (EC 2.7.1.24) (Dephosphocoenzyme A kinase) (DPCOAK)] COASY PSEC0106 Homo sapiens (Human) coenzyme A biosynthetic process [GO:0015937]; phosphorylation [GO:0016310] extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741] ATP binding [GO:0005524]; dephospho-CoA kinase activity [GO:0004140]; pantetheine-phosphate adenylyltransferase activity [GO:0004595] 0.77166 0.26786 LASILTSAAR 0 10.3545 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13077 TRAF1_HUMAN TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6) TRAF1 EBI6 Homo sapiens (Human) apoptotic process [GO:0006915]; positive regulation of JNK cascade [GO:0046330]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of extrinsic apoptotic signaling pathway [GO:2001236]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; tumor necrosis factor-mediated signaling pathway [GO:0033209] cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829] identical protein binding [GO:0042802]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270] 0.80893 0.22928 LQSPKHAYVKDDTMFLK 0 0 0 0 0 0 0 10.1795 0 0 0 0 0 0 0 0 0 0 9.86813 10.176 0 0 10.3572 0 0 0 12.5321 Q13084 RM28_HUMAN "Large ribosomal subunit protein bL28m (39S ribosomal protein L28, mitochondrial) (L28mt) (MRP-L28) (Melanoma antigen p15) (Melanoma-associated antigen recognized by T-lymphocytes)" MRPL28 MAAT1 Homo sapiens (Human) mitochondrial translation [GO:0032543]; translation [GO:0006412] cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial large ribosomal subunit [GO:0005762]; mitochondrial ribosome [GO:0005761]; mitochondrion [GO:0005739] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.88954 -0.44173 EFYSEILDK 0 0 0 0 9.14389 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13085 ACACA_HUMAN Acetyl-CoA carboxylase 1 (ACC1) (EC 6.4.1.2) (Acetyl-Coenzyme A carboxylase alpha) (ACC-alpha) ACACA ACAC ACC1 ACCA Homo sapiens (Human) acetyl-CoA metabolic process [GO:0006084]; cellular response to prostaglandin E stimulus [GO:0071380]; fatty acid biosynthetic process [GO:0006633]; fatty-acyl-CoA biosynthetic process [GO:0046949]; lipid homeostasis [GO:0055088]; malonyl-CoA biosynthetic process [GO:2001295]; protein homotetramerization [GO:0051289]; protein metabolic process [GO:0019538]; tissue homeostasis [GO:0001894] actin cytoskeleton [GO:0015629]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; mitochondrion [GO:0005739] acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872] 0.88396 -0.14328 GVISDILDWKTSR 8.53496 0 0 0 0 0 0 0 11.7178 0 0 0 0 0 0 10.3234 0 0 0 0 0 0 11.0556 9.7364 9.57122 0 0 Q13087 PDIA2_HUMAN Protein disulfide-isomerase A2 (EC 5.3.4.1) (Pancreas-specific protein disulfide isomerase) (PDIp) PDIA2 PDIP Homo sapiens (Human) platelet aggregation [GO:0070527]; protein folding [GO:0006457]; protein folding in endoplasmic reticulum [GO:0034975]; protein retention in ER lumen [GO:0006621]; response to endoplasmic reticulum stress [GO:0034976] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788] disulfide oxidoreductase activity [GO:0015036]; protein disulfide isomerase activity [GO:0003756]; protein-disulfide reductase activity [GO:0015035]; steroid binding [GO:0005496] 0.96877 -3.8881 VGPSAMR 10.6484 0 0 0 0 0 0 0 0 13.9553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13093 PAFA_HUMAN Platelet-activating factor acetylhydrolase (PAF acetylhydrolase) (EC 3.1.1.47) (1-alkyl-2-acetylglycerophosphocholine esterase) (2-acetyl-1-alkylglycerophosphocholine esterase) (Group-VIIA phospholipase A2) (gVIIA-PLA2) (LDL-associated phospholipase A2) (LDL-PLA(2)) (PAF 2-acylhydrolase) PLA2G7 PAFAH Homo sapiens (Human) lipid oxidation [GO:0034440]; low-density lipoprotein particle remodeling [GO:0034374]; peptide hormone processing [GO:0016486]; phosphatidylcholine catabolic process [GO:0034638]; plasma lipoprotein particle oxidation [GO:0034441]; platelet activating factor catabolic process [GO:0062234]; platelet activating factor metabolic process [GO:0046469]; positive regulation of inflammatory response [GO:0050729]; positive regulation of monocyte chemotaxis [GO:0090026] cytoplasm [GO:0005737]; extracellular region [GO:0005576]; high-density lipoprotein particle [GO:0034364]; low-density lipoprotein particle [GO:0034362] "1-alkyl-2-acetylglycerophosphocholine esterase activity [GO:0003847]; calcium-independent phospholipase A2 activity [GO:0047499]; hydrolase activity, acting on ester bonds [GO:0016788]; phospholipid binding [GO:0005543]" 0.75781 0.30063 FDMEQLKDSIDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.131 0 12.0426 0 0 0 0 0 0 0 0 11.8068 Q13094 LCP2_HUMAN Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76) LCP2 Homo sapiens (Human) immune response [GO:0006955]; intracellular signal transduction [GO:0035556]; mast cell activation [GO:0045576]; positive regulation of protein kinase activity [GO:0045860]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] cell-cell junction [GO:0005911]; cytosol [GO:0005829]; plasma membrane raft [GO:0044853]; TCR signalosome [GO:0036398] 0.93328 -1.2796 LSQEINKNEER 0 0 0 0 0 0 0 0 0 0 0 10.3407 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13099 IFT88_HUMAN Intraflagellar transport protein 88 homolog (Recessive polycystic kidney disease protein Tg737 homolog) (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) IFT88 TG737 TTC10 Homo sapiens (Human) cilium assembly [GO:0060271]; inner ear receptor cell stereocilium organization [GO:0060122]; intraciliary anterograde transport [GO:0035720]; intraciliary transport [GO:0042073]; kidney development [GO:0001822]; non-motile cilium assembly [GO:1905515]; positive regulation of cilium assembly [GO:0045724]; regulation of autophagosome assembly [GO:2000785]; regulation of cilium assembly [GO:1902017] centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary base [GO:0097546]; ciliary tip [GO:0097542]; cilium [GO:0005929]; cytosol [GO:0005829]; intraciliary transport particle B [GO:0030992]; motile cilium [GO:0031514]; non-motile cilium [GO:0097730]; sperm flagellum [GO:0036126] kinesin binding [GO:0019894] 0.84886 0.11937 AGYNLTICYFAIGDREK 0 0 0 0 9.96679 0 0 0 0 0 0 0 0 0 0 0 0 0 9.76694 0 10.1716 0 0 0 0 0 0 Q13111 CAF1A_HUMAN Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-I p150) (hp150) CHAF1A CAF CAF1P150 Homo sapiens (Human) cell cycle [GO:0007049]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication-dependent chromatin assembly [GO:0006335]; nucleosome assembly [GO:0006334] CAF-1 complex [GO:0033186]; chromatin [GO:0000785]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] chromatin binding [GO:0003682]; chromo shadow domain binding [GO:0070087]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082] 0.96895 -4.4489 AEKAEITRFFQKPK 11.8177 0 0 0 10.4284 10.1388 0 10.4098 11.9431 8.53426 0 9.1724 8.93425 0 0 0 0 0 9.93278 0 0 0 0 0 0 0 0 Q13112 CAF1B_HUMAN Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-I p60) (M-phase phosphoprotein 7) CHAF1B CAF1A CAF1P60 MPHOSPH7 MPP7 Homo sapiens (Human) cell cycle [GO:0007049]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication-dependent chromatin assembly [GO:0006335]; nucleosome assembly [GO:0006334] CAF-1 complex [GO:0033186]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] chromatin binding [GO:0003682]; histone binding [GO:0042393]; unfolded protein binding [GO:0051082] 0.95113 -1.3838 ISIFNEHK 0 0 0 0 0 0 9.3781 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13114 TRAF3_HUMAN TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein 1) (LAP1) (RING-type E3 ubiquitin transferase TRAF3) TRAF3 CAP-1 CRAF1 TRAFAMN Homo sapiens (Human) apoptotic process [GO:0006915]; defense response to virus [GO:0051607]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of JNK cascade [GO:0046330]; positive regulation of type I interferon production [GO:0032481]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; signal transduction [GO:0007165]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; type I interferon-mediated signaling pathway [GO:0060337] CD40 receptor complex [GO:0035631]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endosome [GO:0005768]; mitochondrion [GO:0005739]; serine/threonine protein kinase complex [GO:1902554]; ubiquitin ligase complex [GO:0000151] identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.95955 -1.7503 DLRDHVEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0193 0 9.96175 9.41705 0 10.1534 0 0 0 Q13115 DUS4_HUMAN Dual specificity protein phosphatase 4 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase hVH2) (Mitogen-activated protein kinase phosphatase 2) (MAP kinase phosphatase 2) (MKP-2) DUSP4 MKP2 VH2 Homo sapiens (Human) dephosphorylation [GO:0016311]; endoderm formation [GO:0001706]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of MAPK cascade [GO:0043409]; protein dephosphorylation [GO:0006470] cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] MAP kinase serine/threonine phosphatase activity [GO:1990439]; MAP kinase tyrosine phosphatase activity [GO:0033550]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; myosin phosphatase activity [GO:0017018]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/threonine phosphatase activity [GO:0008330] 0.88889 -0.45294 LEEAFEFVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0651 0 0 0 0 0 0 Q13118 KLF10_HUMAN Krueppel-like factor 10 (EGR-alpha) (Transforming growth factor-beta-inducible early growth response protein 1) (TGFB-inducible early growth response protein 1) (TIEG-1) KLF10 TIEG TIEG1 Homo sapiens (Human) bone mineralization [GO:0030282]; cell-cell signaling [GO:0007267]; cellular response to starvation [GO:0009267]; circadian rhythm [GO:0007623]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of circadian rhythm [GO:0042752]; regulation of transcription by RNA polymerase II [GO:0006357]; somatic stem cell population maintenance [GO:0035019] chromatin [GO:0000785]; nucleus [GO:0005634] "core promoter sequence-specific DNA binding [GO:0001046]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.88975 -0.47244 ESMYSWNKTAEK 0 0 0 0 0 0 0 0 0 0 11.7855 9.93989 0 0 0 0 0 0 0 0 9.86045 10.6935 0 0 0 0 9.79032 Q13123 RED_HUMAN Protein Red (Cytokine IK) (IK factor) (Protein RER) IK RED RER Homo sapiens (Human) "mitotic cell cycle [GO:0000278]; mitotic spindle assembly checkpoint signaling [GO:0007094]; mRNA splicing, via spliceosome [GO:0000398]; protein localization to kinetochore [GO:0034501]" chromosome [GO:0005694]; cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]; U2-type precatalytic spliceosome [GO:0071005] identical protein binding [GO:0042802] 0.91893 -0.89976 IEFKTRLGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1111 0 0 10.3366 0 0 0 0 0 0 0 0 Q13127 REST_HUMAN RE1-silencing transcription factor (Neural-restrictive silencer factor) (X2 box repressor) REST NRSF XBR Homo sapiens (Human) "auditory receptor cell stereocilium organization [GO:0060088]; cardiac muscle cell myoblast differentiation [GO:0060379]; cellular response to electrical stimulus [GO:0071257]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to xenobiotic stimulus [GO:0071466]; chromatin remodeling [GO:0006338]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hematopoietic progenitor cell differentiation [GO:0002244]; modification of synaptic structure [GO:0099563]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of aldosterone biosynthetic process [GO:0032348]; negative regulation of amniotic stem cell differentiation [GO:2000798]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cortisol biosynthetic process [GO:2000065]; negative regulation of dense core granule biogenesis [GO:2000706]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of insulin secretion [GO:0046676]; negative regulation of mesenchymal stem cell differentiation [GO:2000740]; negative regulation of miRNA transcription [GO:1902894]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; nervous system process [GO:0050877]; neuromuscular process controlling balance [GO:0050885]; neuronal stem cell population maintenance [GO:0097150]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of programmed cell death [GO:0043068]; positive regulation of stem cell population maintenance [GO:1902459]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of DNA-templated transcription [GO:0006355]; regulation of osteoblast differentiation [GO:0045667]; response to hypoxia [GO:0001666]; response to ischemia [GO:0002931]; somatic stem cell population maintenance [GO:0035019]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription repressor complex [GO:0017053] "chromatin binding [GO:0003682]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription cis-regulatory region binding [GO:0000976]" 0.78558 0.25647 EADLPDNITNEK 10.6504 10.6519 0 0 0 0 0 0 0 0 0 10.9873 0 0 0 9.64728 0 0 0 0 0 0 0 0 0 0 0 Q13129 RLF_HUMAN Zinc finger protein Rlf (Rearranged L-myc fusion gene protein) (Zn-15-related protein) RLF Homo sapiens (Human) positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA methylation [GO:0044030]; regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]" 0.91472 -0.82936 ALAKHCSDSHNLDHIEEPK 0 0 0 0 0 0 8.59965 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1293 9.17083 9.58387 8.9882 Q13133 NR1H3_HUMAN Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear receptor subfamily 1 group H member 3) NR1H3 LXRA Homo sapiens (Human) apoptotic cell clearance [GO:0043277]; cell differentiation [GO:0030154]; cellular response to lipopolysaccharide [GO:0071222]; cholesterol homeostasis [GO:0042632]; hormone-mediated signaling pathway [GO:0009755]; lipid homeostasis [GO:0055088]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of inflammatory response [GO:0050728]; negative regulation of lipid transport [GO:0032369]; negative regulation of macrophage activation [GO:0043031]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of pancreatic juice secretion [GO:0090188]; negative regulation of pinocytosis [GO:0048550]; negative regulation of proteolysis [GO:0045861]; negative regulation of response to endoplasmic reticulum stress [GO:1903573]; negative regulation of secretion of lysosomal enzymes [GO:0090341]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type II interferon-mediated signaling pathway [GO:0060336]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cholesterol transport [GO:0032376]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of fatty acid biosynthetic process [GO:0045723]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of lipoprotein lipase activity [GO:0051006]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transporter activity [GO:0032411]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of circadian rhythm [GO:0042752]; response to progesterone [GO:0032570]; sterol homeostasis [GO:0055092]; triglyceride homeostasis [GO:0070328] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; receptor complex [GO:0043235]; RNA polymerase II transcription regulator complex [GO:0090575] "cholesterol binding [GO:0015485]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; nuclear receptor activity [GO:0004879]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sterol response element binding [GO:0032810]; transcription cis-regulatory region binding [GO:0000976]; zinc ion binding [GO:0008270]" 0.7377 0.32576 GAHYICHSGGHCPMDTYMRRK 0 0 0 0 0 0 10.0013 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.021 0 Q13136 LIPA1_HUMAN Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) PPFIA1 LIP1 Homo sapiens (Human) brain development [GO:0007420]; cell-matrix adhesion [GO:0007160]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of stress fiber assembly [GO:0051497]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; signal transduction [GO:0007165]; synapse organization [GO:0050808] axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; membrane [GO:0016020]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; spine apparatus [GO:0097444] 0.95976 -1.9334 AEERHGNIEER 0 0 0 0 0 9.63303 0 0 0 9.42192 0 0 0 11.31 0 0 8.64032 0 0 0 0 9.07919 0 0 10.4485 0 0 Q13144 EI2BE_HUMAN Translation initiation factor eIF-2B subunit epsilon (eIF-2B GDP-GTP exchange factor subunit epsilon) EIF2B5 EIF2BE Homo sapiens (Human) aging [GO:0007568]; astrocyte development [GO:0014002]; astrocyte differentiation [GO:0048708]; hippocampus development [GO:0021766]; myelination [GO:0042552]; oligodendrocyte development [GO:0014003]; ovarian follicle development [GO:0001541]; positive regulation of apoptotic process [GO:0043065]; positive regulation of translational initiation [GO:0045948]; response to endoplasmic reticulum stress [GO:0034976]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to lithium ion [GO:0010226]; response to peptide hormone [GO:0043434]; T cell receptor signaling pathway [GO:0050852]; translational initiation [GO:0006413] cytoplasm [GO:0005737]; cytosol [GO:0005829]; eukaryotic translation initiation factor 2B complex [GO:0005851]; nucleus [GO:0005634] guanyl-nucleotide exchange factor activity [GO:0005085]; translation initiation factor activity [GO:0003743]; translation initiation factor binding [GO:0031369] 0.88275 -0.11231 DVDAKALVR 0 0 0 9.04617 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.7187 0 0 Q13148 TADBP_HUMAN TAR DNA-binding protein 43 (TDP-43) TARDBP TDP43 Homo sapiens (Human) 3'-UTR-mediated mRNA destabilization [GO:0061158]; 3'-UTR-mediated mRNA stabilization [GO:0070935]; amyloid fibril formation [GO:1990000]; mRNA processing [GO:0006397]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of gene expression [GO:0010629]; negative regulation of protein phosphorylation [GO:0001933]; nuclear inner membrane organization [GO:0071765]; positive regulation of protein import into nucleus [GO:0042307]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of circadian rhythm [GO:0042752]; regulation of gene expression [GO:0010468]; regulation of protein stability [GO:0031647]; rhythmic process [GO:0048511]; RNA splicing [GO:0008380] cytoplasmic stress granule [GO:0010494]; intracellular non-membrane-bounded organelle [GO:0043232]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; molecular condensate scaffold activity [GO:0140693]; mRNA 3'-UTR binding [GO:0003730]; pre-mRNA intronic binding [GO:0097157]; RNA binding [GO:0003723]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.88858 -0.42636 DLKTGHSKGFGFVR 0 0 0 0 0 0 0 0 0 0 15.2416 0 0 0 0 0 0 9.38888 0 0 0 10.6921 0 0 0 0 0 Q13151 ROA0_HUMAN Heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0) HNRNPA0 HNRPA0 Homo sapiens (Human) "3'-UTR-mediated mRNA stabilization [GO:0070935]; inflammatory response [GO:0006954]; mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; response to lipopolysaccharide [GO:0032496]" nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; synapse [GO:0045202] mRNA 3'-UTR AU-rich region binding [GO:0035925]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723] 0.84881 0.15779 DQNGLSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6014 0 0 0 0 0 0 0 0 0 0 Q13153 PAK1_HUMAN Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) (PAK-1) (p65-PAK) PAK1 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; apoptotic process [GO:0006915]; branching morphogenesis of an epithelial tube [GO:0048754]; cell migration [GO:0016477]; chromatin remodeling [GO:0006338]; DNA damage response [GO:0006974]; ephrin receptor signaling pathway [GO:0048013]; exocytosis [GO:0006887]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; intracellular signal transduction [GO:0035556]; localization [GO:0051179]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; neuron projection morphogenesis [GO:0048812]; phosphorylation [GO:0016310]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of stress fiber assembly [GO:0051496]; protein autophosphorylation [GO:0046777]; protein localization to cytoplasmic stress granule [GO:1903608]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of axonogenesis [GO:0050770]; regulation of MAPK cascade [GO:0043408]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; wound healing [GO:0042060] actin filament [GO:0005884]; axon [GO:0030424]; cell-cell junction [GO:0005911]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; focal adhesion [GO:0005925]; intercalated disc [GO:0014704]; lamellipodium [GO:0030027]; microtubule organizing center [GO:0005815]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; Z disc [GO:0030018] ATP binding [GO:0005524]; collagen binding [GO:0005518]; gamma-tubulin binding [GO:0043015]; identical protein binding [GO:0042802]; molecular adaptor activity [GO:0060090]; molecular function inhibitor activity [GO:0140678]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0 4.3655 DVATSPISPTENNTTPPDALTR 0 0 0 0 0 0 8.93993 9.22166 8.99464 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13155 AIMP2_HUMAN Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (Multisynthase complex auxiliary component p38) (Protein JTV-1) AIMP2 JTV1 PRO0992 Homo sapiens (Human) apoptotic process [GO:0006915]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of aminoacyl-tRNA ligase activity [GO:1903632]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein ubiquitination [GO:0031398]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; translation [GO:0006412]; type II pneumocyte differentiation [GO:0060510] aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634] molecular adaptor activity [GO:0060090] 0.75344 0.30947 LLCEHFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.11946 0 0 0 0 0 0 0 0 0 0 0 Q13162 PRDX4_HUMAN Peroxiredoxin-4 (EC 1.11.1.24) (Antioxidant enzyme AOE372) (AOE37-2) (Peroxiredoxin IV) (Prx-IV) (Thioredoxin peroxidase AO372) (Thioredoxin-dependent peroxide reductase A0372) (Thioredoxin-dependent peroxiredoxin 4) PRDX4 Homo sapiens (Human) cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774] identical protein binding [GO:0042802]; molecular adaptor activity [GO:0060090]; molecular sequestering activity [GO:0140313]; thioredoxin peroxidase activity [GO:0008379] 0 3.8074 DYGVYLEDSGHTLR 9.21087 8.93602 0 0 0 0 9.72077 9.68787 9.84634 9.37957 9.84699 9.35498 0 0 0 0 0 11.2728 0 0 0 0 0 0 11.9317 0 0 Q13177 PAK2_HUMAN Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) (p21-activated kinase 2) (PAK-2) (p58) [Cleaved into: PAK-2p27 (p27); PAK-2p34 (p34) (C-t-PAK2)] PAK2 Homo sapiens (Human) adherens junction assembly [GO:0034333]; apoptotic process [GO:0006915]; bicellular tight junction assembly [GO:0070830]; cardiac muscle hypertrophy [GO:0003300]; cellular response to organic cyclic compound [GO:0071407]; cellular response to transforming growth factor beta stimulus [GO:0071560]; dendritic spine development [GO:0060996]; intracellular signal transduction [GO:0035556]; localization [GO:0051179]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:2001271]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of stress fiber assembly [GO:0051497]; peptidyl-serine phosphorylation [GO:0018105]; phosphorylation [GO:0016310]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; protein autophosphorylation [GO:0046777]; protein localization to cell-cell junction [GO:0150105]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cytoskeleton organization [GO:0051493]; regulation of MAPK cascade [GO:0043408]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; secretory granule [GO:0030141] ATP binding [GO:0005524]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activator activity [GO:0030296]; small GTPase binding [GO:0031267] 0.93253 -1.2661 LLQTSNITK 0 0 0 0 0 9.35154 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13188 STK3_HUMAN Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)] STK3 KRS1 MST2 Homo sapiens (Human) apoptotic process [GO:0006915]; canonical Wnt signaling pathway [GO:0060070]; cell differentiation involved in embryonic placenta development [GO:0060706]; central nervous system development [GO:0007417]; endocardium development [GO:0003157]; epithelial cell proliferation [GO:0050673]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; hepatocyte apoptotic process [GO:0097284]; hippo signaling [GO:0035329]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of organ growth [GO:0046621]; neural tube formation [GO:0001841]; organ growth [GO:0035265]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase B signaling [GO:0051897]; primitive hemopoiesis [GO:0060215]; protein import into nucleus [GO:0006606]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; regulation of cell differentiation involved in embryonic placenta development [GO:0060800]; regulation of MAPK cascade [GO:0043408]; selective autophagy [GO:0061912]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activator activity [GO:0043539]; protein serine/threonine kinase activity [GO:0004674] 0.72607 0.35404 EQPPAPK 0 0 0 0 0 0 0 0 0 9.31624 0 0 9.2447 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13190 STX5_HUMAN Syntaxin-5 STX5 STX5A Homo sapiens (Human) "early endosome to Golgi transport [GO:0034498]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi disassembly [GO:0090166]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; regulation of Golgi organization [GO:1903358]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906]; vesicle fusion with Golgi apparatus [GO:0048280]" cytosol [GO:0005829]; endomembrane system [GO:0012505]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; SNARE complex [GO:0031201]; vesicle [GO:0031982] cadherin binding [GO:0045296]; SNAP receptor activity [GO:0005484]; SNARE binding [GO:0000149] 0.96355 -2.201 IGKDLSNTFAK 0 9.34649 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13191 CBLB_HUMAN E3 ubiquitin-protein ligase CBL-B (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56) (RING-type E3 ubiquitin transferase CBL-B) (SH3-binding protein CBL-B) (Signal transduction protein CBL-B) CBLB RNF56 Nbla00127 Homo sapiens (Human) "CD4-positive, alpha-beta T cell proliferation [GO:0035739]; immune response [GO:0006955]; intracellular signal transduction [GO:0035556]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of T cell receptor signaling pathway [GO:0050860]; NLS-bearing protein import into nucleus [GO:0006607]; peptidyl-amino acid modification [GO:0018193]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of T cell anergy [GO:0002669]; protein catabolic process [GO:0030163]; protein ubiquitination [GO:0016567]; regulation of GTPase activity [GO:0043087]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; regulation of protein binding [GO:0043393]; signal transduction [GO:0007165]; T cell anergy [GO:0002870]; T cell receptor signaling pathway [GO:0050852]" cytosol [GO:0005829]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.86526 0.078705 ADAAEFWR 0 0 0 0 9.49721 0 0 0 10.3763 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1394 0 0 0 Q13200 PSMD2_HUMAN 26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Protein 55.11) (Tumor necrosis factor type 1 receptor-associated protein 2) PSMD2 TRAP2 Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of protein catabolic process [GO:0042176] "cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome accessory complex [GO:0022624]; proteasome complex [GO:0000502]; proteasome regulatory particle [GO:0005838]; proteasome regulatory particle, base subcomplex [GO:0008540]; proteasome storage granule [GO:0034515]; secretory granule lumen [GO:0034774]" enzyme regulator activity [GO:0030234] 0 3.1622 DKEQELSEEDK 8.52442 8.4953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13202 DUS8_HUMAN Dual specificity protein phosphatase 8 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase hVH-5) DUSP8 C11orf81 VH5 Homo sapiens (Human) dephosphorylation [GO:0016311]; negative regulation of MAPK cascade [GO:0043409]; protein dephosphorylation [GO:0006470] cytoplasm [GO:0005737]; nucleus [GO:0005634] MAP kinase tyrosine phosphatase activity [GO:0033550]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; myosin phosphatase activity [GO:0017018]; phosphatase activity [GO:0016791]; protein tyrosine/threonine phosphatase activity [GO:0008330] 0.93944 -1.3245 KLASLLRGGPGGPLVIDSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.2961 0 0 0 0 0 0 0 0 0 9.27226 0 0 Q13206 DDX10_HUMAN Probable ATP-dependent RNA helicase DDX10 (EC 3.6.4.13) (DEAD box protein 10) DDX10 Homo sapiens (Human) anterior head development [GO:0097065]; rRNA processing [GO:0006364] nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.96858 -3.9261 EARREANK 10.0441 10.1688 9.69537 9.15876 9.28596 0 9.77355 14.7207 9.55298 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7009 0 10.3961 0 8.91196 Q13207 TBX2_HUMAN T-box transcription factor TBX2 (T-box protein 2) TBX2 Homo sapiens (Human) aorta morphogenesis [GO:0035909]; apoptotic process [GO:0006915]; atrioventricular canal development [GO:0036302]; atrioventricular canal morphogenesis [GO:1905222]; cardiac jelly development [GO:1905072]; cardiac muscle cell myoblast differentiation [GO:0060379]; cardiac muscle tissue development [GO:0048738]; cell fate specification [GO:0001708]; cellular senescence [GO:0090398]; cochlea morphogenesis [GO:0090103]; developmental growth involved in morphogenesis [GO:0060560]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic heart tube development [GO:0035050]; endocardial cushion formation [GO:0003272]; endocardial cushion morphogenesis [GO:0003203]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart looping [GO:0001947]; mammary placode formation [GO:0060596]; melanocyte proliferation [GO:0097325]; mesenchymal cell proliferation involved in lung development [GO:0060916]; muscle cell fate determination [GO:0007521]; negative regulation of cardiac chamber formation [GO:1901211]; negative regulation of cellular senescence [GO:2000773]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of heart looping [GO:1901208]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; pharynx development [GO:0060465]; pigment metabolic process involved in pigmentation [GO:0043474]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of heart contraction [GO:0008016]; regulation of transcription by RNA polymerase II [GO:0006357]; response to retinoic acid [GO:0032526]; roof of mouth development [GO:0060021]; smooth muscle cell differentiation [GO:0051145]; ureteric peristalsis [GO:0072105] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription factor binding [GO:0140297]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; histone deacetylase binding [GO:0042826]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.88484 -0.13022 AAGGNSR 0 0 9.79917 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.77517 0 0 0 Q13214 SEM3B_HUMAN Semaphorin-3B (Sema A(V)) (Semaphorin-V) (Sema V) SEMA3B SEMA5 SEMAA Homo sapiens (Human) axon guidance [GO:0007411]; cell-cell signaling [GO:0007267]; chemorepulsion of axon [GO:0061643]; negative chemotaxis [GO:0050919]; negative regulation of axon extension involved in axon guidance [GO:0048843]; neural crest cell migration [GO:0001755]; positive regulation of cell migration [GO:0030335]; semaphorin-plexin signaling pathway [GO:0071526] collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576] chemorepellent activity [GO:0045499]; semaphorin receptor binding [GO:0030215] 0.92727 -1.1886 AERGPRSATHW 0 0 0 9.71339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13216 ERCC8_HUMAN DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA) ERCC8 CKN1 CSA Homo sapiens (Human) DNA damage response [GO:0006974]; double-strand break repair via classical nonhomologous end joining [GO:0097680]; positive regulation of DNA repair [GO:0045739]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of transcription-coupled nucleotide-excision repair [GO:0090262]; response to oxidative stress [GO:0006979]; response to UV [GO:0009411]; response to X-ray [GO:0010165]; single strand break repair [GO:0000012]; transcription-coupled nucleotide-excision repair [GO:0006283] Cul4-RING E3 ubiquitin ligase complex [GO:0080008]; Cul4A-RING E3 ubiquitin ligase complex [GO:0031464]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleotide-excision repair complex [GO:0000109]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] protein-containing complex binding [GO:0044877] 0.92311 -1.1603 ASGCLITLDQHNGK 0 0 0 9.23532 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3083 0 0 0 0 0 0 0 0 Q13217 DNJC3_HUMAN "DnaJ homolog subfamily C member 3 (Endoplasmic reticulum DNA J domain-containing protein 6) (ER-resident protein ERdj6) (ERdj6) (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor of 58 kDa) (Protein kinase inhibitor p58)" DNAJC3 P58IPK PRKRI Homo sapiens (Human) cellular response to cold [GO:0070417]; defense response to virus [GO:0051607]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:1903912]; positive regulation of translation initiation in response to endoplasmic reticulum stress [GO:0036494]; protein folding in endoplasmic reticulum [GO:0034975]; proteolysis involved in protein catabolic process [GO:0051603]; response to unfolded protein [GO:0006986] azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular vesicle [GO:1903561]; membrane [GO:0016020]; smooth endoplasmic reticulum [GO:0005790] misfolded protein binding [GO:0051787]; protein kinase binding [GO:0019901]; protein kinase inhibitor activity [GO:0004860]; protein-folding chaperone binding [GO:0051087] 0.88342 -0.32086 EVLSDPEMRK 11.1032 10.9185 0 9.52337 11.3608 0 10.4067 0 10.1301 12.604 13.116 12.957 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13219 PAPP1_HUMAN Pappalysin-1 (EC 3.4.24.79) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase) (Pregnancy-associated plasma protein A) (PAPP-A) PAPPA Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; female pregnancy [GO:0007565]; protein catabolic process [GO:0030163]; protein metabolic process [GO:0019538]; proteolysis [GO:0006508]; response to dexamethasone [GO:0071548]; response to follicle-stimulating hormone [GO:0032354] extracellular region [GO:0005576]; extracellular space [GO:0005615] metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270] 0.8284 0.20495 GYIEHFSLWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7393 0 0 0 Q13228 SBP1_HUMAN Methanethiol oxidase (MTO) (EC 1.8.3.4) (56 kDa selenium-binding protein) (SBP56) (SP56) (Selenium-binding protein 1) SELENBP1 SBP Homo sapiens (Human) protein transport [GO:0015031] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; fibrillar center [GO:0001650]; membrane [GO:0016020]; nucleolus [GO:0005730] methanethiol oxidase activity [GO:0018549]; selenium binding [GO:0008430] 0 18.671 DGLIPLEIR 9.24041 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7899 10.6286 10.6134 9.99676 11.8741 11.3481 11.8595 11.922 11.0564 11.7037 12.0345 11.5715 Q13233 M3K1_HUMAN Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1) (EC 2.3.2.27) MAP3K1 MAPKKK1 MEKK MEKK1 Homo sapiens (Human) cellular response to mechanical stimulus [GO:0071260]; Fc-epsilon receptor signaling pathway [GO:0038095]; protein phosphorylation [GO:0006468] cytoplasm [GO:0005737]; cytosol [GO:0005829] ATP binding [GO:0005524]; MAP kinase kinase kinase activity [GO:0004709]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; zinc ion binding [GO:0008270] 0.96196 -2.0697 AAAAGNR 0 0 0 0 0 0 0 0 0 0 0 9.22716 0 0 0 0 0 0 0 0 0 0 9.88596 0 0 0 0 Q13237 KGP2_HUMAN cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent protein kinase II) (cGKII) PRKG2 PRKGR2 Homo sapiens (Human) negative regulation of chloride transport [GO:2001226]; peptidyl-serine autophosphorylation [GO:0036289]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of protein localization [GO:1903829]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]; tetrahydrobiopterin metabolic process [GO:0046146] apical plasma membrane [GO:0016324]; cytosol [GO:0005829]; nuclear membrane [GO:0031965] ATP binding [GO:0005524]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; mitogen-activated protein kinase binding [GO:0051019]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310] 0.96066 -2.0139 GIEKMDFPRK 0 0 0 0 0 0 8.58699 0 0 0 13.6405 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13242 SRSF9_HUMAN "Serine/arginine-rich splicing factor 9 (Pre-mRNA-splicing factor SRp30C) (Splicing factor, arginine/serine-rich 9)" SRSF9 SFRS9 SRP30C Homo sapiens (Human) "mRNA processing [GO:0006397]; mRNA splice site selection [GO:0006376]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; response to alkaloid [GO:0043279]; response to toxic substance [GO:0009636]" nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] protein domain specific binding [GO:0019904]; RNA binding [GO:0003723] 0.88541 -0.29534 EIELKNR 0 0 0 0 0 0 0 0 0 0 0 9.28112 0 0 0 0 0 0 0 0 10.07 0 0 0 0 0 0 Q13247 SRSF6_HUMAN "Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6)" SRSF6 SFRS6 SRP55 Homo sapiens (Human) "alternative mRNA splicing, via spliceosome [GO:0000380]; mRNA splice site selection [GO:0006376]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of type B pancreatic cell apoptotic process [GO:2000675]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of keratinocyte proliferation [GO:0010837]; regulation of wound healing [GO:0061041]; response to insulin [GO:0032868]" nuclear speck [GO:0016607]; nucleoplasm [GO:0005654] pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723] 0.21681 0.88579 LIVENLSSR 0 8.83286 0 0 0 0 0 9.86369 0 11.0645 0 0 0 0 9.30232 9.47669 0 0 0 0 0 0 0 0 0 11.5874 10.7939 Q13253 NOGG_HUMAN Noggin NOG Homo sapiens (Human) atrial cardiac muscle tissue morphogenesis [GO:0055009]; axial mesoderm development [GO:0048318]; BMP signaling pathway involved in heart development [GO:0061312]; cartilage development [GO:0051216]; cell differentiation in hindbrain [GO:0021533]; cranial skeletal system development [GO:1904888]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic skeletal joint morphogenesis [GO:0060272]; embryonic skeletal system development [GO:0048706]; endocardial cushion morphogenesis [GO:0003203]; endoderm formation [GO:0001706]; epithelial cell proliferation [GO:0050673]; epithelial to mesenchymal transition [GO:0001837]; exploration behavior [GO:0035640]; face morphogenesis [GO:0060325]; fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation [GO:0060825]; heart trabecula morphogenesis [GO:0061384]; in utero embryonic development [GO:0001701]; limb development [GO:0060173]; long-term synaptic potentiation [GO:0060291]; lung morphogenesis [GO:0060425]; membranous septum morphogenesis [GO:0003149]; mesoderm formation [GO:0001707]; middle ear morphogenesis [GO:0042474]; motor neuron axon guidance [GO:0008045]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cartilage development [GO:0061037]; negative regulation of cell migration [GO:0030336]; negative regulation of cytokine activity [GO:0060302]; negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation [GO:1905006]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; neural plate morphogenesis [GO:0001839]; neural tube closure [GO:0001843]; notochord morphogenesis [GO:0048570]; osteoblast differentiation [GO:0001649]; outflow tract morphogenesis [GO:0003151]; pharyngeal arch artery morphogenesis [GO:0061626]; pituitary gland development [GO:0021983]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of gene expression [GO:0010628]; positive regulation of glomerulus development [GO:0090193]; positive regulation of transcription by RNA polymerase II [GO:0045944]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; prostatic bud formation [GO:0060513]; regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation [GO:2000313]; regulation of neuronal synaptic plasticity [GO:0048168]; short-term synaptic potentiation [GO:1990926]; skeletal system development [GO:0001501]; smoothened signaling pathway [GO:0007224]; somatic stem cell population maintenance [GO:0035019]; somite development [GO:0061053]; spinal cord development [GO:0021510]; stem cell differentiation [GO:0048863]; ureteric bud formation [GO:0060676]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular septum morphogenesis [GO:0060412]; visual learning [GO:0008542]; wound healing [GO:0042060] extracellular region [GO:0005576]; extracellular space [GO:0005615]; presynapse [GO:0098793] cytokine binding [GO:0019955]; protein homodimerization activity [GO:0042803] 0.92532 -0.97157 FWPRYVK 0 0 9.37432 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13255 GRM1_HUMAN Metabotropic glutamate receptor 1 (mGluR1) GRM1 GPRC1A MGLUR1 Homo sapiens (Human) "cellular response to electrical stimulus [GO:0071257]; chemical synaptic transmission [GO:0007268]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; G protein-coupled receptor signaling pathway [GO:0007186]; L-glutamate import across plasma membrane [GO:0098712]; locomotory behavior [GO:0007626]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of MAPK cascade [GO:0043410]; regulation of sensory perception of pain [GO:0051930]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of pain [GO:0019233]" dendrite [GO:0030425]; G protein-coupled receptor dimeric complex [GO:0038037]; G protein-coupled receptor homodimeric complex [GO:0038038]; glutamatergic synapse [GO:0098978]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; Schaffer collateral - CA1 synapse [GO:0098685] adenylate cyclase inhibiting G protein-coupled glutamate receptor activity [GO:0001640]; G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration [GO:0098872]; G protein-coupled receptor activity [GO:0004930]; G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential [GO:0099530]; glutamate receptor activity [GO:0008066]; neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration [GO:0099583] 0.83627 0.18911 AMLDIVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.51566 0 0 0 0 0 0 0 0 0 0 0 0 Q13257 MD2L1_HUMAN Mitotic spindle assembly checkpoint protein MAD2A (HsMAD2) (Mitotic arrest deficient 2-like protein 1) (MAD2-like protein 1) MAD2L1 MAD2 Homo sapiens (Human) cell division [GO:0051301]; establishment of centrosome localization [GO:0051660]; establishment of mitotic spindle orientation [GO:0000132]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint signaling [GO:0007094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of ubiquitin protein ligase activity [GO:1904667]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267] cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; mitotic checkpoint complex [GO:0033597]; mitotic spindle [GO:0072686]; mitotic spindle assembly checkpoint MAD1-MAD2 complex [GO:1990728]; nuclear pore nuclear basket [GO:0044615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; spindle pole [GO:0000922] identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803] 0.92331 -1.1618 WEESGPQFITNSEEVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.75776 0 0 10.138 0 0 0 0 0 0 0 0 0 Q13263 TIF1B_HUMAN Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 2.3.2.27) (KRAB-associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (Nuclear corepressor KAP-1) (RING finger protein 96) (RING-type E3 ubiquitin transferase TIF1-beta) (Tripartite motif-containing protein 28) TRIM28 KAP1 RNF96 TIF1B Homo sapiens (Human) chromatin organization [GO:0006325]; convergent extension involved in axis elongation [GO:0060028]; DNA methylation involved in embryo development [GO:0043045]; DNA repair [GO:0006281]; embryo implantation [GO:0007566]; embryonic placenta morphogenesis [GO:0060669]; epithelial to mesenchymal transition [GO:0001837]; innate immune response [GO:0045087]; negative regulation of DNA demethylation [GO:1901536]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; protein autophosphorylation [GO:0046777]; protein sumoylation [GO:0016925]; regulation of genetic imprinting [GO:2000653]; suppression of viral release by host [GO:0044790] euchromatin [GO:0000791]; heterochromatin [GO:0000792]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; RNA polymerase II transcription regulator complex [GO:0090575] chromatin binding [GO:0003682]; chromo shadow domain binding [GO:0070087]; DNA binding [GO:0003677]; Krueppel-associated box domain binding [GO:0035851]; promoter-specific chromatin binding [GO:1990841]; protein kinase activity [GO:0004672]; RNA binding [GO:0003723]; SUMO transferase activity [GO:0019789]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0 77.533 AASAAAASAAAASAASGSPGPGEGSAGGEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.63423 0 0 0 11.9138 9.95693 8.93949 Q13268 DHRS2_HUMAN "Dehydrogenase/reductase SDR family member 2, mitochondrial (EC 1.1.1.-) (Dicarbonyl reductase HEP27) (Protein D) (Short chain dehydrogenase/reductase family 25C member 1) (Protein SDR25C1)" DHRS2 SDR25C1 Homo sapiens (Human) C21-steroid hormone metabolic process [GO:0008207]; cellular response to oxidative stress [GO:0034599]; electron transport chain [GO:0022900]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; response to toxic substance [GO:0009636] cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "carbonyl reductase (NADPH) activity [GO:0004090]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]" 0.95223 -1.4748 DIRVNCVVPGIIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2398 0 9.60145 Q13275 SEM3F_HUMAN Semaphorin-3F (Sema III/F) (Semaphorin IV) (Sema IV) SEMA3F Homo sapiens (Human) axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; branchiomotor neuron axon guidance [GO:0021785]; facial nerve structural organization [GO:0021612]; negative chemotaxis [GO:0050919]; negative regulation of axon extension involved in axon guidance [GO:0048843]; nerve development [GO:0021675]; neural crest cell migration [GO:0001755]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; positive regulation of cell migration [GO:0030335]; regulation of postsynapse organization [GO:0099175]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; trigeminal nerve structural organization [GO:0021637]; ventral trunk neural crest cell migration [GO:0036486] extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978] chemorepellent activity [GO:0045499]; semaphorin receptor binding [GO:0030215] 0.96716 -2.7986 LYFFFRER 9.82866 0 0 0 0 0 13.0861 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13277 STX3_HUMAN Syntaxin-3 STX3 STX3A Homo sapiens (Human) exocytic insertion of neurotransmitter receptor to postsynaptic membrane [GO:0098967]; intracellular protein transport [GO:0006886]; long-term synaptic potentiation [GO:0060291]; neuron projection development [GO:0031175]; organelle membrane fusion [GO:0090174]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemotaxis [GO:0050921]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of gene expression [GO:0010468]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; vesicle docking [GO:0048278] apical plasma membrane [GO:0016324]; azurophil granule [GO:0042582]; cell-cell junction [GO:0005911]; dendrite [GO:0030425]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; presynaptic active zone membrane [GO:0048787]; Schaffer collateral - CA1 synapse [GO:0098685]; SNARE complex [GO:0031201]; specific granule [GO:0042581]; synaptic vesicle [GO:0008021]; vacuole [GO:0005773]; zymogen granule membrane [GO:0042589] arachidonic acid binding [GO:0050544]; SNAP receptor activity [GO:0005484]; SNARE binding [GO:0000149] 0.89972 -0.68868 ISEHVEEAKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.86448 Q13283 G3BP1_HUMAN Ras GTPase-activating protein-binding protein 1 (G3BP-1) (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent DNA helicase VIII) (hDH VIII) (GAP SH3 domain-binding protein 1) G3BP1 G3BP Homo sapiens (Human) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of stress granule assembly [GO:0062029]; positive regulation of type I interferon production [GO:0032481]; Ras protein signal transduction [GO:0007265]; stress granule assembly [GO:0034063] cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; perikaryon [GO:0043204]; ribonucleoprotein complex [GO:1990904] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; DNA/RNA helicase activity [GO:0033677]; endonuclease activity [GO:0004519]; molecular condensate scaffold activity [GO:0140693]; mRNA binding [GO:0003729]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.45863 0.63894 EAGEQGDIEPR 0 0 0 0 0 0 0 0 0 0 0 9.19967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13287 NMI_HUMAN N-myc-interactor (Nmi) (N-myc and STAT interactor) NMI Homo sapiens (Human) innate immune response [GO:0045087]; macrophage activation involved in immune response [GO:0002281]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; positive regulation of inflammatory response [GO:0050729]; positive regulation of innate immune response [GO:0045089]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein K48-linked ubiquitination [GO:1902524]; protein K48-linked ubiquitination [GO:0070936]; receptor signaling pathway via JAK-STAT [GO:0007259]; response to virus [GO:0009615]; toll-like receptor 4 signaling pathway [GO:0034142] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] identical protein binding [GO:0042802] 0.91749 -0.86694 LELSFSKSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1034 0 0 0 9.69599 0 0 0 0 0 Q13291 SLAF1_HUMAN Signaling lymphocytic activation molecule (CDw150) (IPO-3) (SLAM family member 1) (CD antigen CD150) SLAMF1 SLAM Homo sapiens (Human) adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; innate immune response [GO:0045087]; leukocyte chemotaxis involved in inflammatory response [GO:0002232]; myeloid dendritic cell activation involved in immune response [GO:0002277]; natural killer cell differentiation [GO:0001779]; natural killer cell proliferation [GO:0001787]; negative regulation of CD40 signaling pathway [GO:2000349]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of T cell cytokine production [GO:0002725]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; phagocytosis [GO:0006909]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of type II interferon production [GO:0032729]; regulation of catalytic activity [GO:0050790]; regulation of vesicle fusion [GO:0031338] external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; phagocytic vesicle [GO:0045335] antigen binding [GO:0003823]; identical protein binding [GO:0042802]; SH2 domain binding [GO:0042169]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618] 0.72187 0.3587 SLENSVENK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.61185 0 0 0 0 0 Q13303 KCAB2_HUMAN Voltage-gated potassium channel subunit beta-2 (EC 1.1.1.-) (K(+) channel subunit beta-2) (Kv-beta-2) (hKvbeta2) KCNAB2 KCNA2B KCNK2 Homo sapiens (Human) NADPH oxidation [GO:0070995]; regulation of action potential [GO:0098900]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of protein localization to cell surface [GO:2000008] cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; pinceau fiber [GO:1990031]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; synapse [GO:0045202]; tertiary granule membrane [GO:0070821]; voltage-gated potassium channel complex [GO:0008076] aldo-keto reductase (NADP) activity [GO:0004033]; potassium channel regulator activity [GO:0015459]; transmembrane transporter binding [GO:0044325]; voltage-gated potassium channel activity [GO:0005249] 0.73781 0.3267 YPESTTGSPAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.76653 0 Q13304 GPR17_HUMAN Uracil nucleotide/cysteinyl leukotriene receptor (UDP/CysLT receptor) (G-protein coupled receptor 17) (P2Y-like receptor) (R12) GPR17 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; oligodendrocyte differentiation [GO:0048709]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of Rho protein signal transduction [GO:0035025] plasma membrane [GO:0005886] chemokine receptor activity [GO:0004950]; G protein-coupled receptor activity [GO:0004930]; receptor serine/threonine kinase binding [GO:0033612] 0.96213 -2.6181 MSKRSWWAGSR 0 0 10.2651 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13308 PTK7_HUMAN Inactive tyrosine-protein kinase 7 (Colon carcinoma kinase 4) (CCK-4) (Protein-tyrosine kinase 7) (Pseudo tyrosine kinase receptor 7) (Tyrosine-protein kinase-like 7) PTK7 CCK4 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; axis elongation [GO:0003401]; cell migration [GO:0016477]; cellular response to retinoic acid [GO:0071300]; cochlea morphogenesis [GO:0090103]; convergent extension [GO:0060026]; coronary vasculature development [GO:0060976]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; kidney development [GO:0001822]; lung-associated mesenchyme development [GO:0060484]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of neuron projection development [GO:0010976]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]; synapse organization [GO:0050808]; ventricular septum development [GO:0003281]; wound healing [GO:0042060] axon [GO:0030424]; cell-cell junction [GO:0005911]; focal adhesion [GO:0005925]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886] "ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway [GO:1904929]; protein kinase activity [GO:0004672]" 0.89171 -0.50682 ISKSKDEK 0 0 0 10.7074 0 0 0 0 0 0 0 10.0504 0 0 0 0 0 0 0 8.82563 0 0 0 0 0 0 0 Q13310 PABP4_HUMAN Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP) PABPC4 APP1 PABP4 Homo sapiens (Human) blood coagulation [GO:0007596]; myeloid cell development [GO:0061515]; regulation of mRNA stability [GO:0043488]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; translation [GO:0006412] cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723] 0.96509 -2.2886 AHLTNQYMQR 0 0 0 0 0 0 0 0 0 10.2252 9.25652 0 0 0 11.1525 0 0 10.0031 0 0 0 0 0 0 0 0 0 Q13315 ATM_HUMAN Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T mutated) ATM Homo sapiens (Human) "brain development [GO:0007420]; cellular response to gamma radiation [GO:0071480]; cellular response to nitrosative stress [GO:0071500]; cellular response to reactive oxygen species [GO:0034614]; cellular response to retinoic acid [GO:0071300]; cellular response to X-ray [GO:0071481]; cellular senescence [GO:0090398]; determination of adult lifespan [GO:0008340]; DNA damage checkpoint signaling [GO:0000077]; DNA damage response [GO:0006974]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; establishment of protein-containing complex localization to telomere [GO:0097695]; establishment of RNA localization to telomere [GO:0097694]; female meiotic nuclear division [GO:0007143]; heart development [GO:0007507]; histone mRNA catabolic process [GO:0071044]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lipoprotein catabolic process [GO:0042159]; male meiotic nuclear division [GO:0007140]; meiotic telomere clustering [GO:0045141]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; mitotic spindle assembly checkpoint signaling [GO:0007094]; multicellular organism growth [GO:0035264]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of telomere capping [GO:1904354]; negative regulation of TORC1 signaling [GO:1904262]; neuron apoptotic process [GO:0051402]; oocyte development [GO:0048599]; ovarian follicle development [GO:0001541]; peptidyl-serine autophosphorylation [GO:0036289]; peptidyl-serine phosphorylation [GO:0018105]; pexophagy [GO:0000425]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA catabolic process [GO:1903626]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of telomerase catalytic core complex assembly [GO:1904884]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of telomere maintenance via telomere lengthening [GO:1904358]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; pre-B cell allelic exclusion [GO:0002331]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; reciprocal meiotic recombination [GO:0007131]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of cell cycle [GO:0051726]; regulation of cellular response to gamma radiation [GO:1905843]; regulation of cellular response to heat [GO:1900034]; regulation of microglial cell activation [GO:1903978]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of telomere maintenance via telomerase [GO:0032210]; replicative senescence [GO:0090399]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; signal transduction [GO:0007165]; signal transduction in response to DNA damage [GO:0042770]; somitogenesis [GO:0001756]; telomere maintenance [GO:0000723]; thymus development [GO:0048538]; V(D)J recombination [GO:0033151]" centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; DNA repair complex [GO:1990391]; intracellular membrane-bounded organelle [GO:0043231]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisomal matrix [GO:0005782]; spindle [GO:0005819] 1-phosphatidylinositol-3-kinase activity [GO:0016303]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA-dependent protein kinase activity [GO:0004677]; identical protein binding [GO:0042802]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein-containing complex binding [GO:0044877] 0.96887 -10.997 FLDFFSKAIQCAR 0 0 0 10.6793 0 0 0 0 0 10.74 0 0 0 0 8.42643 0 0 0 0 0 7.88007 0 10.6723 8.65134 13.7225 0 0 Q13322 GRB10_HUMAN Growth factor receptor-bound protein 10 (GRB10 adapter protein) (Insulin receptor-binding protein Grb-IR) GRB10 GRBIR KIAA0207 Homo sapiens (Human) ERK1 and ERK2 cascade [GO:0070371]; gene expression [GO:0010467]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of glucose import [GO:0046325]; negative regulation of glycogen biosynthetic process [GO:0045719]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of phosphorylation [GO:0042326]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of phosphorylation [GO:0042327]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; response to insulin [GO:0032868]; vascular associated smooth muscle cell migration [GO:1904738] cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; signaling receptor complex adaptor activity [GO:0030159] 0.96907 -3.3151 DLCQLLVYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6012 0 0 0 0 0 0 0 0 0 0 0 0 Q13324 CRFR2_HUMAN Corticotropin-releasing factor receptor 2 (CRF-R-2) (CRF-R2) (CRFR-2) (Corticotropin-releasing hormone receptor 2) (CRH-R-2) (CRH-R2) CRHR2 CRF2R CRH2R Homo sapiens (Human) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell surface receptor signaling pathway [GO:0007166]; long-term synaptic potentiation [GO:0060291] axon terminus [GO:0043679]; dendrite [GO:0030425]; plasma membrane [GO:0005886] corticotrophin-releasing factor receptor activity [GO:0015056]; peptide hormone binding [GO:0017046] 0.88448 -0.14244 INYSQCEPILDDKQRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.74863 0 0 0 0 0 0 0 0 Q13325 IFIT5_HUMAN Interferon-induced protein with tetratricopeptide repeats 5 (IFIT-5) (Interferon-induced 58 kDa protein) (Retinoic acid- and interferon-inducible 58 kDa protein) (P58) IFIT5 ISG58 RI58 Homo sapiens (Human) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123] actin cytoskeleton [GO:0015629]; apical part of cell [GO:0045177]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587] double-stranded DNA binding [GO:0003690]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]; single-stranded RNA binding [GO:0003727]; tRNA binding [GO:0000049] 0.88477 -0.19005 SFSLGPLR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.31114 9.18955 0 0 0 0 0 0 0 0 0 0 0 0 Q13326 SGCG_HUMAN Gamma-sarcoglycan (Gamma-SG) (35 kDa dystrophin-associated glycoprotein) (35DAG) SGCG Homo sapiens (Human) cardiac muscle tissue development [GO:0048738]; gene expression [GO:0010467]; heart contraction [GO:0060047]; muscle organ development [GO:0007517] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; plasma membrane [GO:0005886]; sarcoglycan complex [GO:0016012]; sarcolemma [GO:0042383] 0.77155 0.26786 GVHIQAHAGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2353 0 0 0 0 0 0 Q13330 MTA1_HUMAN Metastasis-associated protein MTA1 MTA1 Homo sapiens (Human) chromatin remodeling [GO:0006338]; circadian regulation of gene expression [GO:0032922]; double-strand break repair [GO:0006302]; entrainment of circadian clock by photoperiod [GO:0043153]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; locomotor rhythm [GO:0045475]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein autoubiquitination [GO:1902499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell fate specification [GO:0042659]; regulation of stem cell differentiation [GO:2000736]; response to ionizing radiation [GO:0010212]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NuRD complex [GO:0016581] chromatin binding [GO:0003682]; histone deacetylase binding [GO:0042826]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714] 0.61159 0.42919 AAEAESK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.01978 0 0 0 9.04333 0 0 0 8.93617 0 0 0 Q13332 PTPRS_HUMAN Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma) PTPRS Homo sapiens (Human) cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; corpus callosum development [GO:0022038]; establishment of endothelial intestinal barrier [GO:0090557]; hippocampus development [GO:0021766]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of neuron projection development [GO:0010977]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; spinal cord development [GO:0021510]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling [GO:0099537] axon [GO:0030424]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; presynaptic membrane [GO:0042734]; Schaffer collateral - CA1 synapse [GO:0098685]; synaptic vesicle membrane [GO:0030672] chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine phosphatase activity [GO:0004725] 0.95201 -1.3953 FSVLPPTFHPGDQK 0 0 0 0 0 0 0 0 0 0 8.95841 0 0 0 0 0 0 11.0875 0 0 0 0 0 0 0 0 0 Q13352 CENPR_HUMAN Centromere protein R (CENP-R) (Beta-3-endonexin) (Integrin beta-3-binding protein) (Nuclear receptor-interacting factor 3) ITGB3BP CENPR NRIF3 Homo sapiens (Human) apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; CENP-A containing chromatin assembly [GO:0034080]; regulation of DNA-templated transcription [GO:0006355]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.91998 -0.91277 EMQKTKELMTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6014 0 0 0 0 0 0 0 0 0 0 Q13360 ZN177_HUMAN Zinc finger protein 177 ZNF177 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] blood microparticle [GO:0072562]; nucleus [GO:0005634] "DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.88163 -0.31076 THTGEKPYDCK 0 0 0 9.87851 0 0 0 0 0 0 0 0 0 0 0 0 10.3712 0 0 0 0 0 0 0 0 0 0 Q13362 2A5G_HUMAN Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PP2A B subunit isoform B'-gamma) (PP2A B subunit isoform B56-gamma) (PP2A B subunit isoform PR61-gamma) (PP2A B subunit isoform R5-gamma) (Renal carcinoma antigen NY-REN-29) PPP2R5C KIAA0044 Homo sapiens (Human) "DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; negative regulation of cell population proliferation [GO:0008285]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein dephosphorylation [GO:0006470]; signal transduction [GO:0007165]" "chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein phosphatase type 2A complex [GO:0000159]" protein phosphatase activator activity [GO:0072542]; protein phosphatase regulator activity [GO:0019888] 0.92191 -1.087 ADELASQDGR 13.3109 0 13.1822 0 0 0 12.7918 12.9519 0 0 12.5534 0 0 0 0 12.2538 0 0 0 0 0 0 0 0 0 0 10.4244 Q13363 CTBP1_HUMAN C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-) CTBP1 CTBP Homo sapiens (Human) heterochromatin formation [GO:0031507]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of histone acetylation [GO:0035067]; negative regulation of histone H4 acetylation [GO:0090241]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of histone deacetylation [GO:0031065]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of transcription by RNA polymerase II [GO:0006357]; synaptic vesicle clustering [GO:0097091]; synaptic vesicle endocytosis [GO:0048488]; viral genome replication [GO:0019079]; white fat cell differentiation [GO:0050872] GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; presynaptic active zone cytoplasmic component [GO:0098831]; transcription repressor complex [GO:0017053] "chromatin binding [GO:0003682]; DNA-binding transcription factor binding [GO:0140297]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; protein domain specific binding [GO:0019904]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription coactivator activity [GO:0003713]; transcription coregulator binding [GO:0001221]; transcription corepressor activity [GO:0003714]; transcription corepressor binding [GO:0001222]" 0.95208 -1.4263 EVASGAARIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.0794 0 0 0 0 0 0 Q13367 AP3B2_HUMAN AP-3 complex subunit beta-2 (Adaptor protein complex AP-3 subunit beta-2) (Adaptor-related protein complex 3 subunit beta-2) (Beta-3B-adaptin) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP) AP3B2 Homo sapiens (Human) "anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; clathrin-coated vesicle cargo loading, AP-3-mediated [GO:0035654]; intracellular protein transport [GO:0006886]; intracellular transport [GO:0046907]; synaptic vesicle coating [GO:0016183]; synaptic vesicle recycling [GO:0036465]; vesicle-mediated transport [GO:0016192]" AP-3 adaptor complex [GO:0030123]; axon cytoplasm [GO:1904115]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; Golgi apparatus [GO:0005794]; intracellular vesicle [GO:0097708]; presynapse [GO:0098793] 0.96716 -2.3143 AFYGSEEDEAK 0 0 0 0 0 0 0 9.47145 9.54786 0 0 0 9.92407 9.92102 10.4573 0 0 10.3465 0 0 0 0 0 0 0 0 9.21259 Q13368 MPP3_HUMAN MAGUK p55 subfamily member 3 (Discs large homolog 3) (Protein MPP3) MPP3 DLG3 Homo sapiens (Human) adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell-cell junction [GO:0005911]; plasma membrane [GO:0005886] PDZ domain binding [GO:0030165] 0.96061 -1.9865 AGLIPSK 0 0 0 0 0 0 0 0 0 9.72139 0 0 0 0 0 10.0102 0 0 0 0 8.88258 0 0 0 0 0 0 Q13370 PDE3B_HUMAN "cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (EC 3.1.4.17) (CGIPDE1) (CGIP1) (Cyclic GMP-inhibited phosphodiesterase B) (CGI-PDE B)" PDE3B Homo sapiens (Human) angiogenesis [GO:0001525]; cellular response to insulin stimulus [GO:0032869]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of lipid catabolic process [GO:0050995]; regulation of angiogenesis [GO:0045765]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; guanyl-nucleotide exchange factor complex [GO:0032045]; membrane [GO:0016020] "3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP-inhibited cyclic-nucleotide phosphodiesterase activity [GO:0004119]; metal ion binding [GO:0046872]; protein kinase B binding [GO:0043422]" 0.74681 0.31502 LLVCQVCIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.57809 Q13371 PHLP_HUMAN Phosducin-like protein (PHLP) PDCL PHLOP1 PhLP1 Homo sapiens (Human) cell projection organization [GO:0030030]; heterotrimeric G-protein complex assembly [GO:1902605]; positive regulation of smoothened signaling pathway [GO:0045880]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; signal transduction [GO:0007165]; visual perception [GO:0007601] cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829] 0.41406 0.68633 GPQFKQVFEISSGEGFLDMIDK 0 0 0 0 0 12.5821 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13393 PLD1_HUMAN Phospholipase D1 (PLD 1) (hPLD1) (EC 3.1.4.4) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1) PLD1 Homo sapiens (Human) chemotaxis [GO:0006935]; inositol lipid-mediated signaling [GO:0048017]; phosphatidic acid biosynthetic process [GO:0006654]; phospholipid catabolic process [GO:0009395]; positive regulation of translation [GO:0045727]; Ras protein signal transduction [GO:0007265]; regulation of microvillus assembly [GO:0032534]; regulation of synaptic vesicle cycle [GO:0098693]; regulation of vesicle-mediated transport [GO:0060627]; small GTPase mediated signal transduction [GO:0007264] apical plasma membrane [GO:0016324]; cholinergic synapse [GO:0098981]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821] N-acylphosphatidylethanolamine-specific phospholipase D activity [GO:0070290]; phosphatidylinositol binding [GO:0035091]; phospholipase D activity [GO:0004630] 0.96885 -6.9792 AARDVAR 0 0 0 0 0 0 0 0 0 0 12.1922 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13395 TARB1_HUMAN Probable methyltransferase TARBP1 (EC 2.1.1.-) (TAR RNA-binding protein 1) (TAR RNA-binding protein of 185 kDa) (TRP-185) TARBP1 TRM3 TRP185 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357]; tRNA methylation [GO:0030488] nucleus [GO:0005634] RNA binding [GO:0003723]; tRNA (guanine) methyltransferase activity [GO:0016423] 0.96881 -3.3649 AAGAALR 0 0 0 0 0 0 8.93829 10.6656 0 0 0 11.9345 0 0 0 0 7.96786 11.9186 0 0 0 0 9.71965 0 8.85543 8.34532 0 Q13402 MYO7A_HUMAN Unconventional myosin-VIIa MYO7A USH1B Homo sapiens (Human) actin filament organization [GO:0007015]; actin filament-based movement [GO:0030048]; auditory receptor cell stereocilium organization [GO:0060088]; equilibrioception [GO:0050957]; eye photoreceptor cell development [GO:0042462]; intracellular protein transport [GO:0006886]; lysosome organization [GO:0007040]; mechanoreceptor differentiation [GO:0042490]; phagolysosome assembly [GO:0001845]; pigment granule transport [GO:0051904]; post-embryonic animal organ morphogenesis [GO:0048563]; protein localization [GO:0008104]; sensory organ development [GO:0007423]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; vesicle transport along actin filament [GO:0030050]; visual perception [GO:0007601] actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lysosomal membrane [GO:0005765]; melanosome [GO:0042470]; microvillus [GO:0005902]; myosin complex [GO:0016459]; photoreceptor connecting cilium [GO:0032391]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; stereocilium [GO:0032420]; stereocilium base [GO:0120044]; synapse [GO:0045202]; vesicle [GO:0031982] actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; microfilament motor activity [GO:0000146]; protein domain specific binding [GO:0019904]; spectrin binding [GO:0030507] 0.969 -4.1982 ELCNALADK 9.97169 10.2898 0 0 0 0 0 0 0 0 0 12.4771 0 0 0 0 0 10.1654 0 0 10.3039 0 0 0 11.2413 0 0 Q13404 UB2V1_HUMAN Ubiquitin-conjugating enzyme E2 variant 1 (UEV-1) (CROC-1) (TRAF6-regulated IKK activator 1 beta Uev1A) UBE2V1 CROC1 UBE2V UEV1 P/OKcl.19 Homo sapiens (Human) cell differentiation [GO:0030154]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; regulation of DNA repair [GO:0006282]; regulation of DNA-templated transcription [GO:0006355] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; UBC13-UEV1A complex [GO:0035370]; ubiquitin conjugating enzyme complex [GO:0031371]; ubiquitin ligase complex [GO:0000151] 0.0096852 1.7773 AATTGSGVKVPR 0 0 0 0 0 0 0 0 0 0 9.35863 0 0 0 9.45059 0 0 0 9.67144 0 0 0 9.99986 9.64167 0 9.80053 0 Q13405 RM49_HUMAN "Large ribosomal subunit protein mL49 (39S ribosomal protein L49, mitochondrial) (L49mt) (MRP-L49) (Neighbor of FAU) (NOF) (Protein NOF1)" MRPL49 C11orf4 NOF1 OK/SW-cl.67 Homo sapiens (Human) mitochondrial translation [GO:0032543] mitochondrial inner membrane [GO:0005743]; mitochondrial large ribosomal subunit [GO:0005762]; mitochondrial ribosome [GO:0005761]; mitochondrion [GO:0005739] structural constituent of ribosome [GO:0003735] 0.95454 -1.5117 TGVQRGCGLR 0 0 0 0 0 0 0 0 0 0 9.05444 0 0 0 0 0 0 0 0 9.4957 0 0 0 0 0 0 0 Q13409 DC1I2_HUMAN "Cytoplasmic dynein 1 intermediate chain 2 (Cytoplasmic dynein intermediate chain 2) (Dynein intermediate chain 2, cytosolic) (DH IC-2)" DYNC1I2 DNCI2 DNCIC2 Homo sapiens (Human) microtubule-based movement [GO:0007018]; transport along microtubule [GO:0010970] centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; cytosol [GO:0005829]; dynein complex [GO:0030286]; microtubule [GO:0005874]; vesicle [GO:0031982] dynein heavy chain binding [GO:0045504]; dynein light chain binding [GO:0045503]; microtubule motor activity [GO:0003777] 0.36773 0.73558 TLAEINANR 8.02818 0 0 0 0 0 9.35295 0 9.47982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13410 BT1A1_HUMAN Butyrophilin subfamily 1 member A1 (BT) BTN1A1 BTN Homo sapiens (Human) regulation of cytokine production [GO:0001817]; T cell receptor signaling pathway [GO:0050852] external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102] 0.80772 0.22831 VSDDGEYTCFFR 0 0 0 9.13396 0 0 0 0 0 0 0 0 0 0 0 0 9.17115 0 0 0 0 0 0 0 0 0 0 Q13415 ORC1_HUMAN Origin recognition complex subunit 1 (Replication control protein 1) ORC1 ORC1L PARC1 Homo sapiens (Human) DNA replication initiation [GO:0006270]; mitotic DNA replication checkpoint signaling [GO:0033314] "chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; nuclear origin of replication recognition complex [GO:0005664]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; origin recognition complex [GO:0000808]" ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.89848 -0.65949 VAALSGDARR 0 0 0 0 0 0 0 0 0 9.62339 0 0 0 0 0 0 0 0 0 0 0 9.86414 9.71965 0 0 0 0 Q13418 ILK_HUMAN Integrin-linked protein kinase (EC 2.7.11.1) (59 kDa serine/threonine-protein kinase) (Beta-integrin-linked kinase) (ILK-1) (ILK-2) (p59ILK) ILK ILK1 ILK2 Homo sapiens (Human) branching involved in ureteric bud morphogenesis [GO:0001658]; cell morphogenesis [GO:0000902]; cell projection organization [GO:0030030]; cell-matrix adhesion [GO:0007160]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; fibroblast migration [GO:0010761]; integrin-mediated signaling pathway [GO:0007229]; myelination in peripheral nervous system [GO:0022011]; negative regulation of neural precursor cell proliferation [GO:2000178]; nerve development [GO:0021675]; neural precursor cell proliferation [GO:0061351]; outflow tract morphogenesis [GO:0003151]; peptidyl-serine phosphorylation [GO:0018105]; platelet aggregation [GO:0070527]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of signal transduction [GO:0009967]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; substrate adhesion-dependent cell spreading [GO:0034446]; tumor necrosis factor-mediated signaling pathway [GO:0033209] cytosol [GO:0005829]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; sarcomere [GO:0030017] ATP binding [GO:0005524]; protein kinase binding [GO:0019901]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.55867 0.53787 FDMIVPILEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.91328 0 0 0 0 0 0 0 0 0 0 0 0 Q13421 MSLN_HUMAN "Mesothelin (CAK1 antigen) (Pre-pro-megakaryocyte-potentiating factor) [Cleaved into: Megakaryocyte-potentiating factor (MPF); Mesothelin, cleaved form]" MSLN MPF Homo sapiens (Human) cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; pancreas development [GO:0031016] cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; plasma membrane [GO:0005886] 0.82977 0.20358 QLDVLYPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.2857 0 0 0 0 0 0 0 0 0 Q13423 NNTM_HUMAN "NAD(P) transhydrogenase, mitochondrial (EC 7.1.1.1) (Nicotinamide nucleotide transhydrogenase) (Pyridine nucleotide transhydrogenase)" NNT Homo sapiens (Human) NADPH regeneration [GO:0006740]; proton transmembrane transport [GO:1902600]; reactive oxygen species metabolic process [GO:0072593]; tricarboxylic acid cycle [GO:0006099] membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739] NAD binding [GO:0051287]; NAD(P)+ transhydrogenase (B-specific) activity [GO:0003957]; NAD(P)+ transhydrogenase activity [GO:0008746]; NADP binding [GO:0050661] 0.0058309 2.3453 LLKAISPDKDNFYFDVK 0 0 0 0 0 9.38636 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.08717 0 11.0545 Q13425 SNTB2_HUMAN Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin-3) (SNT3) (Syntrophin-like) (SNTL) SNTB2 D16S2531E SNT2B2 SNTL Homo sapiens (Human) cytoplasm [GO:0005737]; dystrophin-associated glycoprotein complex [GO:0016010]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transport vesicle membrane [GO:0030658] actin binding [GO:0003779]; calmodulin binding [GO:0005516]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198] 0.96805 -2.8766 AGKEVLLEVKFIR 0 0 0 0 8.61021 0 0 0 0 10.7295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13426 XRCC4_HUMAN "DNA repair protein XRCC4 (hXRCC4) (X-ray repair cross-complementing protein 4) [Cleaved into: Protein XRCC4, C-terminus (XRCC4/C)]" XRCC4 Homo sapiens (Human) DNA ligation involved in DNA repair [GO:0051103]; double-strand break repair [GO:0006302]; double-strand break repair via nonhomologous end joining [GO:0006303]; immunoglobulin V(D)J recombination [GO:0033152]; positive regulation of ligase activity [GO:0051351]; positive regulation of phosphatidylserine exposure on apoptotic cell surface [GO:1905782]; protein localization to site of double-strand break [GO:1990166]; response to X-ray [GO:0010165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; DNA ligase IV complex [GO:0032807]; DNA-dependent protein kinase-DNA ligase 4 complex [GO:0005958]; nonhomologous end joining complex [GO:0070419]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861] FHA domain binding [GO:0070975]; identical protein binding [GO:0042802]; molecular adaptor activity [GO:0060090]; nucleic acid binding [GO:0003676] 0.96923 -4.1097 LGSFNLEK 0 0 0 0 0 0 0 0 0 9.29292 0 0 0 0 0 0 0 8.87298 0 0 0 0 0 0 0 0 0 Q13427 PPIG_HUMAN Peptidyl-prolyl cis-trans isomerase G (PPIase G) (Peptidyl-prolyl isomerase G) (EC 5.2.1.8) (CASP10) (Clk-associating RS-cyclophilin) (CARS-Cyp) (CARS-cyclophilin) (SR-cyclophilin) (SR-cyp) (SRcyp) (Cyclophilin G) (Rotamase G) PPIG Homo sapiens (Human) protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; RNA splicing [GO:0008380] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723] 0.96922 -3.2038 DIRRNSEK 0 0 12.0504 0 0 10.295 0 8.81401 12.6908 0 10.1119 8.91292 10.1083 9.0847 10.1064 10.2936 0 10.3692 0 9.38588 0 0 0 0 0 10.9807 0 Q13428 TCOF_HUMAN Treacle protein (Treacher Collins syndrome protein) TCOF1 Homo sapiens (Human) neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; regulation of translation [GO:0006417]; skeletal system development [GO:0001501] cytosol [GO:0005829]; fibrillar center [GO:0001650]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] protein heterodimerization activity [GO:0046982]; protein-macromolecule adaptor activity [GO:0030674]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110] 0.88876 -0.4305 GGALPPAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.90842 8.75666 0 7.92023 0 0 0 0 0 9.24077 11.3565 9.10074 Q13433 S39A6_HUMAN Zinc transporter ZIP6 (Estrogen-regulated protein LIV-1) (Solute carrier family 39 member 6) (Zrt- and Irt-like protein 6) (ZIP-6) SLC39A6 LIV1 ZIP6 Homo sapiens (Human) intracellular monoatomic cation homeostasis [GO:0030003]; intracellular zinc ion homeostasis [GO:0006882]; zinc ion import across plasma membrane [GO:0071578]; zinc ion transmembrane transport [GO:0071577] cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; lamellipodium membrane [GO:0031258]; plasma membrane [GO:0005886] monoatomic cation:bicarbonate symporter activity [GO:0140410]; zinc ion transmembrane transporter activity [GO:0005385] 0.80035 0.24166 KPENDDDVEIK 0 10.1829 10.6679 0 0 0 10.2528 10.4559 10.4328 0 0 0 0 0 0 8.79782 0 0 0 0 0 0 0 0 0 0 0 Q13434 MKRN4_HUMAN Putative E3 ubiquitin-protein ligase makorin-4 (EC 2.3.2.27) (Makorin RING finger protein pseudogene 4) (Makorin RING finger protein pseudogene 5) (RING finger protein 64) (RING-type E3 ubiquitin transferase makorin-4) (Zinc finger protein 127-Xp) (ZNF127-Xp) (Zinc finger protein 127-like 1) MKRN4P MKRN4 MKRNP5 RNF64 ZNF127L1 Homo sapiens (Human) protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630] 0.89893 -0.62282 QKLIQKYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0522 0 0 0 0 0 0 0 0 0 0 0 0 Q13439 GOGA4_HUMAN Golgin subfamily A member 4 (256 kDa golgin) (Golgin-245) (Protein 72.1) (Trans-Golgi p230) GOLGA4 Homo sapiens (Human) Golgi to plasma membrane protein transport [GO:0043001]; Golgi vesicle transport [GO:0048193]; positive regulation of axon extension [GO:0045773]; vesicle-mediated transport [GO:0016192] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802] GTPase binding [GO:0051020]; small GTPase binding [GO:0031267] 0.96923 -7.413 AAFEELEK 10.1292 0 0 0 0 0 8.7654 0 9.24346 0 11.8474 0 9.81152 10.0791 9.41151 0 0 0 8.48091 10.8191 10.3342 0 0 0 9.50162 10.6336 0 Q13442 HAP28_HUMAN 28 kDa heat- and acid-stable phosphoprotein (PDGF-associated protein) (PAP) (PDGFA-associated protein 1) (PAP1) PDAP1 HASPP28 Homo sapiens (Human) signal transduction [GO:0007165] cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; plasma membrane [GO:0005886] RNA binding [GO:0003723] 0.92261 -1.1034 QREEAARK 0 0 0 0 0 0 0 0 0 0 0 9.75995 0 0 0 0 0 0 9.51771 0 0 0 0 0 9.5544 0 0 Q13444 ADA15_HUMAN "Disintegrin and metalloproteinase domain-containing protein 15 (ADAM 15) (EC 3.4.24.-) (Metalloprotease RGD disintegrin protein) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15) (MDC-15) (Metargidin)" ADAM15 MDC15 Homo sapiens (Human) angiogenesis [GO:0001525]; cardiac epithelial to mesenchymal transition [GO:0060317]; cell-matrix adhesion [GO:0007160]; cellular response to phorbol 13-acetate 12-myristate [GO:1904628]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response to tumor cell [GO:0002418]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; male gonad development [GO:0008584]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of receptor binding [GO:1900121]; proteolysis [GO:0006508]; response to hypobaric hypoxia [GO:1990910]; tissue regeneration [GO:0042246] acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; motile cilium [GO:0031514]; plasma membrane [GO:0005886] integrin binding [GO:0005178]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; SH3 domain binding [GO:0017124] 0.96358 -2.2272 ALLARGTK 10.5887 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13451 FKBP5_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP5 (PPIase FKBP5) (EC 5.2.1.8) (51 kDa FK506-binding protein) (51 kDa FKBP) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (Androgen-regulated protein 6) (FF1 antigen) (FK506-binding protein 5) (FKBP-5) (FKBP54) (p54) (HSP90-binding immunophilin) (Rotamase) FKBP5 AIG6 FKBP51 Homo sapiens (Human) chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; response to bacterium [GO:0009617] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654] FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755] 0.89863 -0.61611 NEPFVFSLGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4015 0 11.4982 0 0 0 Q13454 TUSC3_HUMAN Tumor suppressor candidate 3 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3) (Oligosaccharyl transferase subunit TUSC3) (Magnesium uptake/transporter TUSC3) (Protein N33) TUSC3 N33 Homo sapiens (Human) cognition [GO:0050890]; magnesium ion transport [GO:0015693]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]; transmembrane transport [GO:0055085] endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; oligosaccharyltransferase complex [GO:0008250]; plasma membrane [GO:0005886] magnesium ion transmembrane transporter activity [GO:0015095] 0.94089 -1.3115 SIFRMNGDK 0 0 0 0 0 0 0 0 0 0 0 0 9.44857 0 0 0 0 0 9.65485 0 0 0 0 0 0 0 0 Q13459 MYO9B_HUMAN Unconventional myosin-IXb (Unconventional myosin-9b) MYO9B MYR5 Homo sapiens (Human) actin filament-based movement [GO:0030048]; lamellipodium morphogenesis [GO:0072673]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385] actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lamellipodium [GO:0030027]; membrane [GO:0016020]; myosin complex [GO:0016459]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726] actin binding [GO:0003779]; actin filament binding [GO:0051015]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein binding [GO:0043008]; calmodulin binding [GO:0005516]; GTPase activator activity [GO:0005096]; microfilament motor activity [GO:0000146]; Roundabout binding [GO:0048495]; small GTPase binding [GO:0031267]; zinc ion binding [GO:0008270] 0.94129 -1.3126 ITTCVEMLIK 0 0 0 0 0 0 0 0 0 13.0603 0 10.9271 0 0 0 0 0 0 0 0 0 0 9.81298 0 0 9.80119 0 Q13464 ROCK1_HUMAN "Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)" ROCK1 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; aortic valve morphogenesis [GO:0003180]; apical constriction [GO:0003383]; bleb assembly [GO:0032060]; blood vessel diameter maintenance [GO:0097746]; cortical actin cytoskeleton organization [GO:0030866]; embryonic morphogenesis [GO:0048598]; epithelial to mesenchymal transition [GO:0001837]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; membrane to membrane docking [GO:0022614]; mitotic cytokinesis [GO:0000281]; motor neuron apoptotic process [GO:0097049]; mRNA destabilization [GO:0061157]; myoblast migration [GO:0051451]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of angiogenesis [GO:0016525]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of motor neuron apoptotic process [GO:2000672]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of phosphorylation [GO:0042326]; negative regulation of protein binding [GO:0032091]; neuron projection arborization [GO:0140058]; neuron projection development [GO:0031175]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; podocyte cell migration [GO:0090521]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of autophagy [GO:0010508]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of connective tissue replacement [GO:1905205]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatase activity [GO:0010922]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of amyloid-beta formation [GO:1902003]; regulation of angiotensin-activated signaling pathway [GO:0110061]; regulation of autophagy [GO:0010506]; regulation of cell adhesion [GO:0030155]; regulation of cell junction assembly [GO:1901888]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of establishment of cell polarity [GO:2000114]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of focal adhesion assembly [GO:0051893]; regulation of keratinocyte differentiation [GO:0045616]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of neuron differentiation [GO:0045664]; regulation of stress fiber assembly [GO:0051492]; regulation of synapse maturation [GO:0090128]; regulation of synaptic vesicle endocytosis [GO:1900242]; response to angiotensin [GO:1990776]; response to transforming growth factor beta [GO:0071559]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]; smooth muscle contraction [GO:0006939] bleb [GO:0032059]; centriole [GO:0005814]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule lumen [GO:0034774] aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; Rho-dependent protein serine/threonine kinase activity [GO:0072518]; small GTPase binding [GO:0031267]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321] 0.96817 -8.9461 DHLDKKEDLICPCK 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3765 0 0 9.17602 0 9.93886 0 0 8.89406 0 0 9.88769 0 0 Q13469 NFAC2_HUMAN "Nuclear factor of activated T-cells, cytoplasmic 2 (NF-ATc2) (NFATc2) (NFAT pre-existing subunit) (NF-ATp) (T-cell transcription factor NFAT1)" NFATC2 NFAT1 NFATP Homo sapiens (Human) B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; DNA damage response [GO:0006974]; myotube cell development [GO:0014904]; ncRNA transcription [GO:0098781]; negative regulation of vascular associated smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of myoblast fusion [GO:1901741]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; response to xenobiotic stimulus [GO:0009410]; transcription by RNA polymerase II [GO:0006366] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor AP-1 complex [GO:0035976]; transcription regulator complex [GO:0005667] "14-3-3 protein binding [GO:0071889]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.91629 -0.76502 LVFRVHIPESSGR 0 9.8024 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13472 TOP3A_HUMAN DNA topoisomerase 3-alpha (EC 5.6.2.1) (DNA topoisomerase III alpha) TOP3A TOP3 Homo sapiens (Human) chromosome separation [GO:0051304]; DNA topological change [GO:0006265]; double-strand break repair via homologous recombination [GO:0000724]; meiotic cell cycle [GO:0051321]; mitochondrial DNA metabolic process [GO:0032042]; resolution of recombination intermediates [GO:0071139] mitochondrial matrix [GO:0005759]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; RecQ family helicase-topoisomerase III complex [GO:0031422] "DNA binding [GO:0003677]; DNA topoisomerase type I (single strand cut, ATP-independent) activity [GO:0003917]; single-stranded DNA binding [GO:0003697]; zinc ion binding [GO:0008270]" 0.88904 -0.43797 FSGGPPR 9.91286 0 0 0 0 0 0 0 0 0 9.8158 0 0 0 0 0 0 0 0 10.3255 0 10.0153 0 10.1768 0 0 11.6649 Q13474 DRP2_HUMAN Dystrophin-related protein 2 (DRP-2) DRP2 Homo sapiens (Human) central nervous system development [GO:0007417]; synapse organization [GO:0050808]; synaptic signaling [GO:0099536] dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] zinc ion binding [GO:0008270] 0.92915 -1.2295 DTSPKQRIQNLSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.18475 0 0 9.39639 0 0 Q13485 SMAD4_HUMAN Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (SMAD family member 4) (SMAD 4) (Smad4) (hSMAD4) SMAD4 DPC4 MADH4 Homo sapiens (Human) activin receptor signaling pathway [GO:0032924]; adrenal gland development [GO:0030325]; aging [GO:0007568]; anatomical structure morphogenesis [GO:0009653]; atrioventricular canal development [GO:0036302]; atrioventricular valve formation [GO:0003190]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; brainstem development [GO:0003360]; branching involved in ureteric bud morphogenesis [GO:0001658]; cardiac conduction system development [GO:0003161]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to BMP stimulus [GO:0071773]; cellular response to glucose stimulus [GO:0071333]; developmental growth [GO:0048589]; DNA-templated transcription [GO:0006351]; embryonic digit morphogenesis [GO:0042733]; endocardial cell differentiation [GO:0060956]; endoderm development [GO:0007492]; endothelial cell activation [GO:0042118]; epithelial cell migration [GO:0010631]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; ERK1 and ERK2 cascade [GO:0070371]; female gonad morphogenesis [GO:0061040]; formation of anatomical boundary [GO:0048859]; gastrulation with mouth forming second [GO:0001702]; in utero embryonic development [GO:0001701]; interleukin-6-mediated signaling pathway [GO:0070102]; intracellular iron ion homeostasis [GO:0006879]; intracellular signal transduction [GO:0035556]; left ventricular cardiac muscle tissue morphogenesis [GO:0003220]; mesoderm development [GO:0007498]; metanephric mesenchyme morphogenesis [GO:0072133]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of cardiac myofibril assembly [GO:1905305]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nephrogenic mesenchyme morphogenesis [GO:0072134]; neural crest cell differentiation [GO:0014033]; neuron fate commitment [GO:0048663]; osteoblast differentiation [GO:0001649]; outflow tract septum morphogenesis [GO:0003148]; ovarian follicle development [GO:0001541]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell proliferation involved in heart valve morphogenesis [GO:0003251]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of follicle-stimulating hormone secretion [GO:0046881]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of luteinizing hormone secretion [GO:0033686]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; regulation of binding [GO:0051098]; regulation of hair follicle development [GO:0051797]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; regulation of transforming growth factor beta2 production [GO:0032909]; response to hypoxia [GO:0001666]; response to transforming growth factor beta [GO:0071559]; sebaceous gland development [GO:0048733]; secondary palate development [GO:0062009]; seminiferous tubule development [GO:0072520]; single fertilization [GO:0007338]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; somite rostral/caudal axis specification [GO:0032525]; spermatogenesis [GO:0007283]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterus development [GO:0060065]; ventricular septum morphogenesis [GO:0060412]; wound healing [GO:0042060] activin responsive factor complex [GO:0032444]; centrosome [GO:0005813]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; heteromeric SMAD protein complex [GO:0071144]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SMAD protein complex [GO:0071141]; transcription regulator complex [GO:0005667] "chromatin binding [GO:0003682]; collagen binding [GO:0005518]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; filamin binding [GO:0031005]; I-SMAD binding [GO:0070411]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; R-SMAD binding [GO:0070412]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sulfate binding [GO:0043199]; transcription cis-regulatory region binding [GO:0000976]; transcription coactivator binding [GO:0001223]" 0.96823 -2.7789 ETPCWIEIHLHR 0 0 0 9.31637 0 0 0 0 0 0 0 0 0 0 0 0 0 9.64701 0 10.787 0 0 0 0 0 0 0 Q13487 SNPC2_HUMAN snRNA-activating protein complex subunit 2 (SNAPc subunit 2) (Proximal sequence element-binding transcription factor subunit delta) (PSE-binding factor subunit delta) (PTF subunit delta) (Small nuclear RNA-activating complex polypeptide 2) (snRNA-activating protein complex 45 kDa subunit) (SNAPc 45 kDa subunit) SNAPC2 SNAP45 Homo sapiens (Human) snRNA transcription [GO:0009301]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383] cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] RNA polymerase II general transcription initiation factor activity [GO:0016251] 0.89938 -0.6848 APEETPPATEK 10.6786 0 0 0 0 0 10.6415 0 10.456 0 10.4333 0 0 0 0 0 0 9.00068 0 9.83679 0 0 0 0 0 0 0 Q13488 VPP3_HUMAN V-type proton ATPase 116 kDa subunit a 3 (V-ATPase 116 kDa subunit a 3) (Osteoclastic proton pump 116 kDa subunit) (OC-116 kDa) (OC116) (T-cell immune regulator 1) (T-cell immune response cDNA7 protein) (TIRC7) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3) TCIRG1 ATP6N1C ATP6V0A3 Homo sapiens (Human) apoptotic process [GO:0006915]; autophagosome assembly [GO:0000045]; B cell differentiation [GO:0030183]; bone resorption [GO:0045453]; cellular defense response [GO:0006968]; cellular response to cytokine stimulus [GO:0071345]; dentin mineralization [GO:0097188]; enamel mineralization [GO:0070166]; establishment of cell polarity [GO:0030010]; establishment of vesicle localization [GO:0051650]; gene expression [GO:0010467]; hematopoietic stem cell homeostasis [GO:0061484]; immunoglobulin mediated immune response [GO:0016064]; inflammatory response [GO:0006954]; intracellular calcium ion homeostasis [GO:0006874]; lysosomal lumen acidification [GO:0007042]; macroautophagy [GO:0016236]; memory T cell activation [GO:0035709]; optic nerve development [GO:0021554]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; osteoclast proliferation [GO:0002158]; pH reduction [GO:0045851]; phagosome acidification [GO:0090383]; positive regulation of cell population proliferation [GO:0008284]; protein catabolic process in the vacuole [GO:0007039]; protein localization to organelle [GO:0033365]; proton transmembrane transport [GO:1902600]; regulation of gene expression [GO:0010468]; regulation of insulin secretion [GO:0050796]; regulation of osteoblast differentiation [GO:0045667]; regulation of proton transport [GO:0010155]; response to silver ion [GO:0010272]; retina development in camera-type eye [GO:0060041]; ruffle organization [GO:0031529]; T cell differentiation [GO:0030217]; T cell homeostasis [GO:0043029]; T-helper 1 cell activation [GO:0035711]; tooth eruption [GO:0044691]; vacuolar acidification [GO:0007035] "apical plasma membrane [GO:0016324]; endosome membrane [GO:0010008]; ficolin-1-rich granule membrane [GO:0101003]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; nucleus [GO:0005634]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; proton-transporting V-type ATPase complex [GO:0033176]; vacuolar proton-transporting V-type ATPase complex [GO:0016471]; vacuolar proton-transporting V-type ATPase, V0 domain [GO:0000220]" "ATPase binding [GO:0051117]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]" 0.88421 -0.28214 APALERLLWR 0 0 0 0 0 0 0 0 0 0 10.1727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13490 BIRC2_HUMAN Baculoviral IAP repeat-containing protein 2 (EC 2.3.2.27) (Cellular inhibitor of apoptosis 1) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (hIAP-2) (hIAP2) (RING finger protein 48) (RING-type E3 ubiquitin transferase BIRC2) (TNFR2-TRAF-signaling complex protein 2) BIRC2 API1 MIHB RNF48 Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of necroptotic process [GO:0060546]; negative regulation of ripoptosome assembly involved in necroptotic process [GO:1902443]; NIK/NF-kappaB signaling [GO:0038061]; placenta development [GO:0001890]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein K48-linked ubiquitination [GO:1902524]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; regulation of cysteine-type endopeptidase activity [GO:2000116]; regulation of inflammatory response [GO:0050727]; regulation of innate immune response [GO:0045088]; regulation of necroptotic process [GO:0060544]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of RIG-I signaling pathway [GO:0039535]; regulation of toll-like receptor signaling pathway [GO:0034121]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; tumor necrosis factor-mediated signaling pathway [GO:0033209] CD40 receptor complex [GO:0035631]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; membrane raft [GO:0045121]; nucleus [GO:0005634]; XY body [GO:0001741] cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; FBXO family protein binding [GO:0098770]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; protein-folding chaperone binding [GO:0051087]; transcription coactivator activity [GO:0003713]; transferase activity [GO:0016740]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.85041 0.11731 LFPGPSYQNIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3488 0 0 0 0 0 0 0 0 0 0 0 0 Q13492 PICAL_HUMAN Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia protein) PICALM CALM Homo sapiens (Human) amyloid-beta clearance by transcytosis [GO:0150093]; axonogenesis [GO:0007409]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; dendrite morphogenesis [GO:0048813]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; hemopoiesis [GO:0030097]; intracellular iron ion homeostasis [GO:0006879]; learning or memory [GO:0007611]; membrane bending [GO:0097753]; multicellular organismal-level iron ion homeostasis [GO:0060586]; negative regulation of gene expression [GO:0010629]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of receptor-mediated endocytosis [GO:0048261]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron death [GO:1901216]; protein-containing complex assembly [GO:0065003]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902959]; regulation of endocytosis [GO:0030100]; regulation of protein localization [GO:0032880]; regulation of vesicle size [GO:0097494]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle maturation [GO:0016188]; vesicle budding from membrane [GO:0006900]; vesicle cargo loading [GO:0035459]; vesicle-mediated transport [GO:0016192] cell surface [GO:0009986]; clathrin coat of coated pit [GO:0030132]; clathrin-coated endocytic vesicle [GO:0045334]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome to plasma membrane transport vesicle [GO:0070381]; extrinsic component of presynaptic endocytic zone membrane [GO:0098894]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; neurofibrillary tangle [GO:0097418]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synaptic vesicle [GO:0008021]; vesicle [GO:0031982] "1-phosphatidylinositol binding [GO:0005545]; amyloid-beta binding [GO:0001540]; cadherin binding [GO:0045296]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; small GTPase binding [GO:0031267]; SNARE binding [GO:0000149]; tau protein binding [GO:0048156]" 0.95003 -1.3838 FIQYLASR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.85552 0 0 Q13496 MTM1_HUMAN "Myotubularin (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64)" MTM1 CG2 Homo sapiens (Human) autophagosome assembly [GO:0000045]; endosome to lysosome transport [GO:0008333]; intermediate filament organization [GO:0045109]; mitochondrion distribution [GO:0048311]; mitochondrion morphogenesis [GO:0070584]; muscle cell cellular homeostasis [GO:0046716]; negative regulation of autophagosome assembly [GO:1902902]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of skeletal muscle tissue growth [GO:0048633]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein dephosphorylation [GO:0006470]; protein kinase B signaling [GO:0043491]; protein transport [GO:0015031]; regulation of vacuole organization [GO:0044088]; skeletal muscle tissue growth [GO:0048630]; TOR signaling [GO:0031929] cytoplasm [GO:0005737]; cytosol [GO:0005829]; filopodium [GO:0030175]; I band [GO:0031674]; late endosome [GO:0005770]; plasma membrane [GO:0005886]; ruffle [GO:0001726] "intermediate filament binding [GO:0019215]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity [GO:0052629]; phosphatidylinositol-3-phosphate phosphatase activity [GO:0004438]; phosphoprotein phosphatase activity [GO:0004721]" 0.91655 -0.8436 ASASTSK 11.4318 10.5167 10.1232 10.1866 0 0 0 0 9.21546 0 0 0 9.94303 9.94635 8.98687 0 0 0 0 0 0 0 0 0 0 0 0 Q13501 SQSTM_HUMAN Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62) SQSTM1 ORCA OSIL Homo sapiens (Human) aggrephagy [GO:0035973]; apoptotic process [GO:0006915]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; brown fat cell proliferation [GO:0070342]; cell differentiation [GO:0030154]; cellular response to reactive oxygen species [GO:0034614]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; energy homeostasis [GO:0097009]; immune system process [GO:0002376]; intracellular signal transduction [GO:0035556]; macroautophagy [GO:0016236]; mitophagy [GO:0000423]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pexophagy [GO:0000425]; positive regulation of apoptotic process [GO:0043065]; positive regulation of autophagy [GO:0010508]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein catabolic process [GO:0030163]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein localization to perinuclear region of cytoplasm [GO:1905719]; protein phosphorylation [GO:0006468]; protein targeting to vacuole involved in autophagy [GO:0071211]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mitochondrion organization [GO:0010821]; regulation of protein complex stability [GO:0061635]; regulation of Ras protein signal transduction [GO:0046578]; response to ischemia [GO:0002931]; response to mitochondrial depolarisation [GO:0098780]; selective autophagy [GO:0061912]; temperature homeostasis [GO:0001659]; transcription by RNA polymerase II [GO:0006366]; ubiquitin-dependent protein catabolic process [GO:0006511] aggresome [GO:0016235]; amphisome [GO:0044753]; autolysosome [GO:0044754]; autophagosome [GO:0005776]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; Lewy body [GO:0097413]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; phagophore assembly site [GO:0000407]; PML body [GO:0016605]; sarcomere [GO:0030017]; sperm midpiece [GO:0097225] enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; ionotropic glutamate receptor binding [GO:0035255]; K63-linked polyubiquitin modification-dependent protein binding [GO:0070530]; protein kinase binding [GO:0019901]; protein kinase C binding [GO:0005080]; protein serine/threonine kinase activity [GO:0004674]; protein-containing complex binding [GO:0044877]; protein-macromolecule adaptor activity [GO:0030674]; receptor tyrosine kinase binding [GO:0030971]; SH2 domain binding [GO:0042169]; signaling adaptor activity [GO:0035591]; signaling receptor activity [GO:0038023]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-dependent protein binding [GO:0140036]; zinc ion binding [GO:0008270] 0 4.0361 EAALYPHLPPEADPR 8.7344 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13508 NAR3_HUMAN Ecto-ADP-ribosyltransferase 3 (EC 2.4.2.31) (ADP-ribosyltransferase C2 and C3 toxin-like 3) (ARTC3) (Mono(ADP-ribosyl)transferase 3) (NAD(P)(+)--arginine ADP-ribosyltransferase 3) ART3 TMART Homo sapiens (Human) extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; plasma membrane [GO:0005886] NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+-protein-arginine ADP-ribosyltransferase activity [GO:0106274]; nucleotidyltransferase activity [GO:0016779] 0.96803 -3.66 EEKASHQQLDTVWENAK 0 0 0 0 0 10.6855 0 0 0 0 0 9.85077 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13509 TBB3_HUMAN Tubulin beta-3 chain (Tubulin beta-4 chain) (Tubulin beta-III) TUBB3 TUBB4 Homo sapiens (Human) axon guidance [GO:0007411]; dorsal root ganglion development [GO:1990791]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] axon [GO:0030424]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; growth cone [GO:0030426]; intercellular bridge [GO:0045171]; lamellipodium [GO:0030027]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; mitotic spindle [GO:0072686]; neuronal cell body [GO:0043025]; nucleus [GO:0005634] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; netrin receptor binding [GO:1990890]; peptide binding [GO:0042277]; structural constituent of cytoskeleton [GO:0005200] 0.77191 0.27086 AILVDLEPGTMDSVR 0 0 0 0 0 0 0 0 0 9.60359 0 0 11.1541 0 11.2886 0 0 0 0 0 0 0 0 0 0 0 0 Q13523 PRP4B_HUMAN Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing factor 4 homolog) PRPF4B KIAA0536 PRP4 PRP4H PRP4K Homo sapiens (Human) "mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; protein phosphorylation [GO:0006468]; RNA splicing [GO:0008380]" catalytic step 2 spliceosome [GO:0071013]; chromosome [GO:0005694]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; RNA binding [GO:0003723] 0.96949 -4.6338 AKHNLMTVEQNNGSSQK 10.2746 10.0686 14.7089 0 0 0 9.33255 10.5578 0 11.6321 0 9.94314 11.5221 0 11.2081 11.093 11.0624 0 9.90501 9.22971 12.3016 12.9787 0 0 12.3011 12.2937 12.3894 Q13535 ATR_HUMAN Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1) ATR FRP1 Homo sapiens (Human) "cellular response to gamma radiation [GO:0071480]; cellular response to UV [GO:0034644]; DNA damage checkpoint signaling [GO:0000077]; DNA damage response [GO:0006974]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; establishment of protein-containing complex localization to telomere [GO:0097695]; establishment of RNA localization to telomere [GO:0097694]; interstrand cross-link repair [GO:0036297]; negative regulation of DNA replication [GO:0008156]; nucleobase-containing compound metabolic process [GO:0006139]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; positive regulation of telomerase catalytic core complex assembly [GO:1904884]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein autophosphorylation [GO:0046777]; protein localization to chromosome, telomeric region [GO:0070198]; protein phosphorylation [GO:0006468]; regulation of cellular response to heat [GO:1900034]; regulation of double-strand break repair [GO:2000779]; replication fork processing [GO:0031297]; replicative senescence [GO:0090399]; response to arsenic-containing substance [GO:0046685]; response to xenobiotic stimulus [GO:0009410]; telomere maintenance [GO:0000723]" ATR-ATRIP complex [GO:0070310]; chromosome [GO:0005694]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605] ATP binding [GO:0005524]; DNA binding [GO:0003677]; MutLalpha complex binding [GO:0032405]; MutSalpha complex binding [GO:0032407]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.89962 -0.60924 AGRSDRVQMR 0 0 0 0 0 9.2863 0 0 0 10.3999 0 0 8.93056 0 0 10.0545 0 0 0 0 0 0 0 9.78383 0 12.408 0 Q13546 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1) RIPK1 RIP RIP1 Homo sapiens (Human) amyloid fibril formation [GO:1990000]; apoptotic process [GO:0006915]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to tumor necrosis factor [GO:0071356]; extrinsic apoptotic signaling pathway [GO:0097191]; inflammatory response [GO:0006954]; necroptotic process [GO:0070266]; necroptotic signaling pathway [GO:0097527]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of necroptotic process [GO:0060546]; peptidyl-serine autophosphorylation [GO:0036289]; positive regulation of apoptotic process [GO:0043065]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of gene expression [GO:0010628]; positive regulation of hydrogen peroxide-induced cell death [GO:1905206]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-6-mediated signaling pathway [GO:0070105]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of necroptotic process [GO:0060545]; positive regulation of necrotic cell death [GO:0010940]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; regulation of ATP:ADP antiporter activity [GO:0070926]; response to tumor necrosis factor [GO:0034612]; ripoptosome assembly [GO:0097343]; ripoptosome assembly involved in necroptotic process [GO:1901026]; T cell apoptotic process [GO:0070231]; tumor necrosis factor-mediated signaling pathway [GO:0033209] cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; endosome membrane [GO:0010008]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ripoptosome [GO:0097342] ATP binding [GO:0005524]; death domain binding [GO:0070513]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; JUN kinase kinase kinase activity [GO:0004706]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein-containing complex binding [GO:0044877]; ubiquitin protein ligase binding [GO:0031625] 0.92339 -1.0503 QQPRQNVAYNR 0 0 0 0 0 0 0 0 0 9.5558 9.54413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13547 HDAC1_HUMAN Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-) HDAC1 RPD3L1 Homo sapiens (Human) cellular response to platelet-derived growth factor stimulus [GO:0036120]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; circadian regulation of gene expression [GO:0032922]; DNA methylation-dependent heterochromatin formation [GO:0006346]; embryonic digit morphogenesis [GO:0042733]; endoderm development [GO:0007492]; epidermal cell differentiation [GO:0009913]; eyelid development in camera-type eye [GO:0061029]; fungiform papilla formation [GO:0061198]; hair follicle placode formation [GO:0060789]; hippocampus development [GO:0021766]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron differentiation [GO:0030182]; odontogenesis of dentin-containing tooth [GO:0042475]; oligodendrocyte differentiation [GO:0048709]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deacetylation [GO:0006476]; regulation of amyloid-beta clearance [GO:1900221]; regulation of cell fate specification [GO:0042659]; regulation of endopeptidase activity [GO:0052548]; regulation of stem cell differentiation [GO:2000736]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; heterochromatin [GO:0000792]; histone deacetylase complex [GO:0000118]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NuRD complex [GO:0016581]; protein-containing complex [GO:0032991]; Sin3 complex [GO:0016580]; transcription repressor complex [GO:0017053] core promoter sequence-specific DNA binding [GO:0001046]; DNA-binding transcription factor binding [GO:0140297]; E-box binding [GO:0070888]; enzyme binding [GO:0019899]; histone deacetylase activity [GO:0004407]; histone deacetylase binding [GO:0042826]; histone decrotonylase activity [GO:0160009]; Krueppel-associated box domain binding [GO:0035851]; NF-kappaB binding [GO:0051059]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protein lysine deacetylase activity [GO:0033558]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription corepressor activity [GO:0003714]; transcription corepressor binding [GO:0001222] 0.92435 -1.031 DIGAGKGKYYAVNYPLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8118 0 0 0 0 0 0 0 0 0 0 Q13557 KCC2D_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17) CAMK2D CAMKD Homo sapiens (Human) cardiac muscle cell contraction [GO:0086003]; cellular response to calcium ion [GO:0071277]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; negative regulation of sodium ion transmembrane transport [GO:1902306]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1902514]; regulation of cardiac muscle cell action potential [GO:0098901]; regulation of cardiac muscle cell action potential involved in regulation of contraction [GO:0098909]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling [GO:0010649]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cell growth [GO:0001558]; regulation of cellular localization [GO:0060341]; regulation of heart contraction [GO:0008016]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of histone deacetylase activity [GO:1901725]; regulation of membrane depolarization [GO:0003254]; regulation of relaxation of cardiac muscle [GO:1901897]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of the force of heart contraction [GO:0002026]; regulation of transcription by RNA polymerase II [GO:0006357]; relaxation of cardiac muscle [GO:0055119] calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; sarcolemma [GO:0042383]; sarcoplasmic reticulum membrane [GO:0033017] ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; sodium channel inhibitor activity [GO:0019871]; titin binding [GO:0031432]; transmembrane transporter binding [GO:0044325] 0.81436 0.22147 IPTGQEYAAK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.96464 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13563 PKD2_HUMAN Polycystin-2 (PC2) (Autosomal dominant polycystic kidney disease type II protein) (Polycystic kidney disease 2 protein) (Polycystwin) (R48321) (Transient receptor potential cation channel subfamily P member 2) PKD2 TRPP2 Homo sapiens (Human) "aorta development [GO:0035904]; branching involved in ureteric bud morphogenesis [GO:0001658]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell-cell signaling by wnt [GO:0198738]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrostatic pressure [GO:0071464]; cellular response to osmotic stress [GO:0071470]; cellular response to reactive oxygen species [GO:0034614]; centrosome duplication [GO:0051298]; cilium organization [GO:0044782]; cytoplasmic sequestering of transcription factor [GO:0042994]; detection of mechanical stimulus [GO:0050982]; detection of nodal flow [GO:0003127]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; embryonic placenta development [GO:0001892]; establishment of localization in cell [GO:0051649]; heart development [GO:0007507]; heart looping [GO:0001947]; inorganic cation transmembrane transport [GO:0098662]; intracellular calcium ion homeostasis [GO:0006874]; liver development [GO:0001889]; mesonephric duct development [GO:0072177]; mesonephric tubule development [GO:0072164]; metanephric ascending thin limb development [GO:0072218]; metanephric cortex development [GO:0072214]; metanephric cortical collecting duct development [GO:0072219]; metanephric distal tubule development [GO:0072235]; metanephric mesenchyme development [GO:0072075]; metanephric part of ureteric bud development [GO:0035502]; metanephric S-shaped body morphogenesis [GO:0072284]; metanephric smooth muscle tissue development [GO:0072208]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; neural tube development [GO:0021915]; placenta blood vessel development [GO:0060674]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of gene expression [GO:0010628]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of transcription by RNA polymerase II [GO:0045944]; potassium ion transmembrane transport [GO:0071805]; protein heterotetramerization [GO:0051290]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of calcium ion import [GO:0090279]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; release of sequestered calcium ion into cytosol [GO:0051209]; renal artery morphogenesis [GO:0061441]; renal tubule morphogenesis [GO:0061333]; sodium ion transmembrane transport [GO:0035725]; spinal cord development [GO:0021510]; Wnt signaling pathway [GO:0016055]" basal cortex [GO:0045180]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cation channel complex [GO:0034703]; cell-cell junction [GO:0005911]; ciliary basal body [GO:0036064]; ciliary membrane [GO:0060170]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; lamellipodium [GO:0030027]; lumenal side of endoplasmic reticulum membrane [GO:0098553]; membrane [GO:0016020]; mitotic spindle [GO:0072686]; motile cilium [GO:0031514]; non-motile cilium [GO:0097730]; plasma membrane [GO:0005886]; polycystin complex [GO:0002133] actinin binding [GO:0042805]; ATPase binding [GO:0051117]; calcium ion binding [GO:0005509]; calcium-induced calcium release activity [GO:0048763]; cytoskeletal protein binding [GO:0008092]; HLH domain binding [GO:0043398]; identical protein binding [GO:0042802]; monoatomic cation channel activity [GO:0005261]; muscle alpha-actinin binding [GO:0051371]; outward rectifier potassium channel activity [GO:0015271]; phosphoprotein binding [GO:0051219]; potassium channel activity [GO:0005267]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; transmembrane transporter binding [GO:0044325]; voltage-gated calcium channel activity [GO:0005245]; voltage-gated monoatomic cation channel activity [GO:0022843]; voltage-gated monoatomic ion channel activity [GO:0005244]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated sodium channel activity [GO:0005248] 0.96726 -2.7999 IDAVIVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3038 0 0 0 0 0 0 0 Q13568 IRF5_HUMAN Interferon regulatory factor 5 (IRF-5) IRF5 Homo sapiens (Human) cellular response to virus [GO:0098586]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of transcription by RNA polymerase II [GO:0006357]; response to muramyl dipeptide [GO:0032495]; response to peptidoglycan [GO:0032494] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96597 -2.7258 CALNKSRDFR 10.8723 10.5091 10.9319 0 10.1719 0 10.3909 10.4913 10.3712 10.6094 10.5345 10.2469 9.07502 9.07612 9.46023 0 9.2267 0 0 0 0 0 0 0 0 0 0 Q13571 LAPM5_HUMAN Lysosomal-associated transmembrane protein 5 (Lysosomal-associated multitransmembrane protein 5) (Retinoic acid-inducible E3 protein) LAPTM5 KIAA0085 Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; defense response to tumor cell [GO:0002357]; Golgi to lysosome transport [GO:0090160]; induction of programmed cell death [GO:0012502]; intracellular protein transport [GO:0006886]; negative regulation of autophagic cell death [GO:1904093]; negative regulation of B cell activation [GO:0050869]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of T cell activation [GO:0050868]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of type II interferon production [GO:0032689]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of lysosomal membrane permeability [GO:0097214]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of receptor catabolic process [GO:2000646]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein targeting to lysosome [GO:0006622] cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; transport vesicle [GO:0030133] protein sequestering activity [GO:0140311]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-dependent protein binding [GO:0140036] 0.91538 -0.79255 CMNSVEEKR 0 0 0 11.1314 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13572 ITPK1_HUMAN "Inositol-tetrakisphosphate 1-kinase (EC 2.7.1.134) (Inositol 1,3,4-trisphosphate 5/6-kinase) (Inositol-triphosphate 5/6-kinase) (Ins(1,3,4)P(3) 5/6-kinase) (EC 2.7.1.159)" ITPK1 Homo sapiens (Human) blood coagulation [GO:0007596]; inositol trisphosphate metabolic process [GO:0032957]; necroptotic process [GO:0070266]; neural tube development [GO:0021915]; phosphorylation [GO:0016310]; signal transduction [GO:0007165] apical plasma membrane [GO:0016324]; cytosol [GO:0005829] "ATP binding [GO:0005524]; catalytic activity [GO:0003824]; hydrolase activity [GO:0016787]; inositol tetrakisphosphate 1-kinase activity [GO:0047325]; inositol tetrakisphosphate 6-kinase activity [GO:0000825]; inositol-1,3,4-trisphosphate 5-kinase activity [GO:0052726]; inositol-1,3,4-trisphosphate 6-kinase activity [GO:0052725]; isomerase activity [GO:0016853]; magnesium ion binding [GO:0000287]" 0.89759 -0.67837 TLLDRSKSYELIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.72093 0 0 0 0 0 0 0 0 0 10.1353 Q13573 SNW1_HUMAN SNW domain-containing protein 1 (Nuclear protein SkiP) (Nuclear receptor coactivator NCoA-62) (Ski-interacting protein) SNW1 SKIIP SKIP Homo sapiens (Human) "cellular response to retinoic acid [GO:0071300]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of neurogenesis [GO:0050769]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of vitamin D receptor signaling pathway [GO:0070564]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of vitamin D receptor signaling pathway [GO:0070562]; retinoic acid receptor signaling pathway [GO:0048384]" catalytic step 2 spliceosome [GO:0071013]; nuclear body [GO:0016604]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2-type catalytic step 2 spliceosome [GO:0071007] enzyme binding [GO:0019899]; Notch binding [GO:0005112]; nuclear androgen receptor binding [GO:0050681]; nuclear receptor binding [GO:0016922]; nuclear retinoic acid receptor binding [GO:0042974]; nuclear vitamin D receptor binding [GO:0042809]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714] 0.96197 -2.4653 AGIKTHVEK 0 0 0 0 8.93552 8.70089 0 8.35036 8.58105 0 0 0 0 0 0 0 0 0 0 0 0 0 8.41815 0 0 0 0 Q13574 DGKZ_HUMAN Diacylglycerol kinase zeta (DAG kinase zeta) (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) DGKZ DAGK6 Homo sapiens (Human) "cell migration [GO:0016477]; diacylglycerol metabolic process [GO:0046339]; glycerolipid metabolic process [GO:0046486]; intracellular signal transduction [GO:0035556]; lipid phosphorylation [GO:0046834]; mitotic G1 DNA damage checkpoint signaling [GO:0031571]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of T cell receptor signaling pathway [GO:0050860]; phosphatidic acid biosynthetic process [GO:0006654]; platelet activation [GO:0030168]; positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity [GO:0090216]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of synaptic transmission, glutamatergic [GO:0051966]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; lamellipodium [GO:0030027]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; diacylglycerol kinase activity [GO:0004143]; kinase activity [GO:0016301]; lipid kinase activity [GO:0001727]; metal ion binding [GO:0046872] 0.97013 -3.2962 AQDTELAAYLENR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.14756 0 0 0 0 0 0 8.44836 0 0 0 0 Q13576 IQGA2_HUMAN Ras GTPase-activating-like protein IQGAP2 IQGAP2 Homo sapiens (Human) Arp2/3 complex-mediated actin nucleation [GO:0034314]; mitotic actomyosin contractile ring assembly actin filament organization [GO:1903479]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of GTPase activity [GO:0043087]; signal transduction [GO:0007165]; thrombin-activated receptor signaling pathway [GO:0070493] actin cytoskeleton [GO:0015629]; cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; microtubule [GO:0005874]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667] "actin binding [GO:0003779]; actin filament binding [GO:0051015]; Arp2/3 complex binding [GO:0071933]; calmodulin binding [GO:0005516]; GTPase activator activity [GO:0005096]; GTPase inhibitor activity [GO:0005095]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; small GTPase binding [GO:0031267]" 0.96932 -3.5756 FLGVEMEK 0 8.84483 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3094 0 0 0 10.8417 0 0 0 0 Q13585 MTR1L_HUMAN Melatonin-related receptor (G protein-coupled receptor 50) (H9) GPR50 Homo sapiens (Human) cell-cell signaling [GO:0007267]; G protein-coupled receptor signaling pathway [GO:0007186] nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; melatonin receptor activity [GO:0008502] 0.71538 0.36595 TLARARAHAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.75221 0 0 0 0 0 0 0 0 0 0 0 Q13586 STIM1_HUMAN Stromal interaction molecule 1 STIM1 GOK Homo sapiens (Human) activation of store-operated calcium channel activity [GO:0032237]; detection of calcium ion [GO:0005513]; enamel mineralization [GO:0070166]; intracellular calcium ion homeostasis [GO:0006874]; positive regulation of adenylate cyclase activity [GO:0045762]; positive regulation of angiogenesis [GO:0045766]; regulation of calcium ion transport [GO:0051924]; regulation of store-operated calcium entry [GO:2001256]; store-operated calcium entry [GO:0002115] cortical endoplasmic reticulum [GO:0032541]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; microtubule [GO:0005874]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; sarcoplasmic reticulum membrane [GO:0033017] calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; microtubule plus-end binding [GO:0051010]; protease binding [GO:0002020] 0.92327 -1.1571 LHKAQEEHR 0 0 0 0 0 0 0 0 0 0 9.44363 0 0 0 0 0 0 0 9.68096 0 0 0 0 9.0184 0 0 0 Q13595 TRA2A_HUMAN Transformer-2 protein homolog alpha (TRA-2 alpha) (TRA2-alpha) (Transformer-2 protein homolog A) TRA2A Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]" intracellular membrane-bounded organelle [GO:0043231]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681] RNA binding [GO:0003723] 0.91521 -0.79194 SHSPMSNRR 0 0 0 9.06824 0 10.3016 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13596 SNX1_HUMAN Sorting nexin-1 SNX1 Homo sapiens (Human) "early endosome to Golgi transport [GO:0034498]; intracellular protein transport [GO:0006886]; lamellipodium morphogenesis [GO:0072673]; positive regulation of protein catabolic process [GO:0045732]; receptor internalization [GO:0031623]; retrograde transport, endosome to Golgi [GO:0042147]" "cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; lysosome [GO:0005764]; membrane [GO:0016020]; protein-containing complex [GO:0032991]; retromer complex [GO:0030904]; retromer, tubulation complex [GO:0030905]; vesicle [GO:0031982]" cadherin binding [GO:0045296]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; leptin receptor binding [GO:1990460]; phosphatidylinositol binding [GO:0035091]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; transferrin receptor binding [GO:1990459] 0.96181 -2.0453 EVIRFEKEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.70058 0 0 0 0 0 0 0 Q13601 KRR1_HUMAN KRR1 small subunit processome component homolog (HIV-1 Rev-binding protein 2) (KRR-R motif-containing protein 1) (Rev-interacting protein 1) (Rip-1) KRR1 HRB2 Homo sapiens (Human) ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364] chromosome [GO:0005694]; cytoplasm [GO:0005737]; intercellular bridge [GO:0045171]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040] RNA binding [GO:0003723] 0.91603 -0.77342 KTFDPYIIIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.15831 0 0 0 0 Q13608 PEX6_HUMAN Peroxisomal ATPase PEX6 (EC 3.6.4.-) (Peroxin-6) (Peroxisomal biogenesis factor 6) (Peroxisomal-type ATPase 1) (Peroxisome assembly factor 2) (PAF-2) PEX6 PXAAA1 Homo sapiens (Human) "peroxisome organization [GO:0007031]; protein import into peroxisome matrix [GO:0016558]; protein import into peroxisome matrix, receptor recycling [GO:0016562]; protein import into peroxisome matrix, translocation [GO:0016561]; protein stabilization [GO:0050821]; protein targeting to peroxisome [GO:0006625]; protein unfolding [GO:0043335]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; photoreceptor cell cilium [GO:0097733]; photoreceptor outer segment [GO:0001750] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; protein transporter activity [GO:0140318]; protein-containing complex binding [GO:0044877]; ubiquitin-dependent protein binding [GO:0140036] 0.87042 0.039062 LVFVGANEDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.66342 0 0 0 Q13609 DNSL3_HUMAN Deoxyribonuclease gamma (DNase gamma) (EC 3.1.21.-) (DNase I homolog protein DHP2) (Deoxyribonuclease I-like 3) (DNase I-like 3) (Liver and spleen DNase) (LS-DNase) (LSD) DNASE1L3 DHP2 DNAS1L3 Homo sapiens (Human) apoptotic DNA fragmentation [GO:0006309]; DNA catabolic process [GO:0006308]; DNA metabolic process [GO:0006259]; neutrophil activation involved in immune response [GO:0002283]; programmed cell death involved in cell development [GO:0010623]; regulation of acute inflammatory response [GO:0002673]; regulation of neutrophil mediated cytotoxicity [GO:0070948] endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; nucleus [GO:0005634] calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA endonuclease activity [GO:0004520]; DNA nuclease activity [GO:0004536] 0.72455 0.3558 FVWLIGDQEDTTVK 0 0 10.5462 0 10.1261 0 0 11.1438 0 0 0 10.9503 0 0 0 0 0 0 0 0 9.57257 0 0 0 0 0 0 Q13610 PWP1_HUMAN Periodic tryptophan protein 1 homolog (Keratinocyte protein IEF SSP 9502) PWP1 Homo sapiens (Human) DNA-templated transcription [GO:0006351]; negative regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033140]; positive regulation of stem cell differentiation [GO:2000738]; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901838]; rRNA processing [GO:0006364] chromosome [GO:0005694]; Golgi apparatus [GO:0005794]; nucleolus [GO:0005730]; nucleus [GO:0005634] H4K20me3 modified histone binding [GO:1990889]; histone chaperone activity [GO:0140713] 0.92442 -0.99061 MNRSRQVTCVAWVR 0 0 10.1678 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13614 MTMR2_HUMAN "Myotubularin-related protein 2 (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64)" MTMR2 KIAA1073 Homo sapiens (Human) dendritic spine maintenance [GO:0097062]; myelin assembly [GO:0032288]; negative regulation of endocytosis [GO:0045806]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of myelination [GO:0031642]; negative regulation of receptor catabolic process [GO:2000645]; negative regulation of receptor internalization [GO:0002091]; neuron development [GO:0048666]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of early endosome to late endosome transport [GO:2000643]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol dephosphorylation [GO:0060304] axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; synaptic membrane [GO:0097060]; synaptic vesicle [GO:0008021]; vacuolar membrane [GO:0005774] "identical protein binding [GO:0042802]; phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity [GO:0052629]; phosphatidylinositol-3-phosphate phosphatase activity [GO:0004438]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]" 0.43963 0.64743 DVTYICPFTGAVR 0 0 0 0 0 0 0 0 0 0 9.92239 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13615 MTMR3_HUMAN "Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64) (Zinc finger FYVE domain-containing protein 10)" MTMR3 KIAA0371 ZFYVE10 Homo sapiens (Human) cellular response to glucose starvation [GO:0042149]; macroautophagy [GO:0016236]; phosphatidylinositol 5-phosphate metabolic process [GO:1904562]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; protein dephosphorylation [GO:0006470]; regulation of autophagosome assembly [GO:2000785]; regulation of autophagy [GO:0010506]; regulation of phosphatidylinositol dephosphorylation [GO:0060304] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020] "metal ion binding [GO:0046872]; phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity [GO:0052629]; phosphatidylinositol-3-phosphate phosphatase activity [GO:0004438]; protein phosphatase binding [GO:0019903]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]" 0.94742 -1.3546 DIFQLHLTCKDCKVIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.3292 Q13616 CUL1_HUMAN Cullin-1 (CUL-1) CUL1 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell population proliferation [GO:0008283]; G1/S transition of mitotic cell cycle [GO:0000082]; intrinsic apoptotic signaling pathway [GO:0097193]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] cullin-RING ubiquitin ligase complex [GO:0031461]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Parkin-FBXW7-Cul1 ubiquitin ligase complex [GO:1990452]; plasma membrane [GO:0005886]; SCF ubiquitin ligase complex [GO:0019005] protein-macromolecule adaptor activity [GO:0030674]; ubiquitin ligase complex scaffold activity [GO:0160072]; ubiquitin protein ligase binding [GO:0031625] 0.87101 0.064272 GIYEIYSLALVTWR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.10682 0 Q13617 CUL2_HUMAN Cullin-2 (CUL-2) CUL2 Homo sapiens (Human) G1/S transition of mitotic cell cycle [GO:0000082]; intrinsic apoptotic signaling pathway [GO:0097193]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] Cul2-RING ubiquitin ligase complex [GO:0031462]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; SCF ubiquitin ligase complex [GO:0019005]; VCB complex [GO:0030891] protein-containing complex binding [GO:0044877]; protein-macromolecule adaptor activity [GO:0030674]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842] 0.95373 -1.5003 DVFQKFYAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.20215 0 0 0 0 0 Q13618 CUL3_HUMAN Cullin-3 (CUL-3) CUL3 KIAA0617 Homo sapiens (Human) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell migration [GO:0016477]; cell projection organization [GO:0030030]; COPII vesicle coating [GO:0048208]; embryonic cleavage [GO:0040016]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibroblast apoptotic process [GO:0044346]; G1/S transition of mitotic cell cycle [GO:0000082]; gastrulation [GO:0007369]; gene expression [GO:0010467]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway [GO:0097193]; liver morphogenesis [GO:0072576]; mitotic metaphase plate congression [GO:0007080]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon production [GO:0032480]; nuclear protein quality control by the ubiquitin-proteasome system [GO:0071630]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of mitotic cell cycle phase transition [GO:1901992]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of protein ubiquitination [GO:0031398]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein destabilization [GO:0031648]; protein K48-linked ubiquitination [GO:0070936]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation protein catabolic process at postsynapse [GO:0140252]; stem cell division [GO:0017145]; stress fiber assembly [GO:0043149]; trophectodermal cellular morphogenesis [GO:0001831]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055] centrosome [GO:0005813]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; mitotic spindle [GO:0072686]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; polar microtubule [GO:0005827]; postsynapse [GO:0098794]; sperm flagellum [GO:0036126]; spindle pole [GO:0000922] cyclin binding [GO:0030332]; identical protein binding [GO:0042802]; Notch binding [GO:0005112]; POZ domain binding [GO:0031208]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625] 0.96681 -2.842 DQVVRYGCIRDHLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.70482 0 0 0 0 0 0 12.0919 Q13620 CUL4B_HUMAN Cullin-4B (CUL-4B) CUL4B KIAA0695 Homo sapiens (Human) astrocyte differentiation [GO:0048708]; cellular response to UV [GO:0034644]; DNA damage response [GO:0006974]; G1/S transition of mitotic cell cycle [GO:0000082]; gene expression [GO:0010467]; neuron projection development [GO:0031175]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of protein catabolic process [GO:0045732]; proteasomal protein catabolic process [GO:0010498]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; ribosome biogenesis [GO:0042254]; ubiquitin-dependent protein catabolic process [GO:0006511]; UV-damage excision repair [GO:0070914] Cul4-RING E3 ubiquitin ligase complex [GO:0080008]; Cul4A-RING E3 ubiquitin ligase complex [GO:0031464]; Cul4B-RING E3 ubiquitin ligase complex [GO:0031465]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ubiquitin protein ligase binding [GO:0031625] 0.9457 -1.343 DVFEAFYKKDLAK 0 0 0 0 0 0 0 0 0 0 0 0 10.1173 0 9.66256 11.9272 0 0 0 8.99367 0 0 0 0 10.4109 11.4996 0 Q13621 S12A1_HUMAN Solute carrier family 12 member 1 (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2) (Kidney-specific Na-K-Cl symporter) SLC12A1 NKCC2 Homo sapiens (Human) cell volume homeostasis [GO:0006884]; chloride ion homeostasis [GO:0055064]; chloride transmembrane transport [GO:1902476]; monoatomic ion transmembrane transport [GO:0034220]; monoatomic ion transport [GO:0006811]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; sodium ion homeostasis [GO:0055078]; sodium ion transmembrane transport [GO:0035725] apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886] sodium:potassium:chloride symporter activity [GO:0008511] 0.84492 0.13413 ESWKVFEEMIEPYR 12.0419 0 10.4566 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13625 ASPP2_HUMAN Apoptosis-stimulating of p53 protein 2 (Bcl2-binding protein) (Bbp) (Renal carcinoma antigen NY-REN-51) (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2) TP53BP2 ASPP2 BBP Homo sapiens (Human) cell cycle [GO:0007049]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; negative regulation of cell cycle [GO:0045786]; positive regulation of execution phase of apoptosis [GO:1900119]; signal transduction [GO:0007165] cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; p53 binding [GO:0002039]; SH3 domain binding [GO:0017124] 0.96845 -3.6123 ELQLRNK 0 0 0 0 0 0 0 0 9.77525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13634 CAD18_HUMAN Cadherin-18 (Cadherin-14) CDH18 CDH14 Homo sapiens (Human) adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] adherens junction [GO:0005912]; catenin complex [GO:0016342]; plasma membrane [GO:0005886] cadherin binding [GO:0045296]; calcium ion binding [GO:0005509] 0.89763 -0.67859 LHSNSDKGDGSVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2603 0 10.9035 0 0 0 0 0 0 0 0 0 Q13635 PTC1_HUMAN Protein patched homolog 1 (PTC) (PTC1) PTCH1 PTCH Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell differentiation involved in kidney development [GO:0061005]; cell fate determination [GO:0001709]; cell proliferation involved in metanephros development [GO:0072203]; cellular response to cholesterol [GO:0071397]; commissural neuron axon guidance [GO:0071679]; dorsal/ventral neural tube patterning [GO:0021904]; dorsal/ventral pattern formation [GO:0009953]; embryonic limb morphogenesis [GO:0030326]; embryonic organ development [GO:0048568]; epidermal cell fate specification [GO:0009957]; glucose homeostasis [GO:0042593]; heart morphogenesis [GO:0003007]; hindlimb morphogenesis [GO:0035137]; in utero embryonic development [GO:0001701]; keratinocyte proliferation [GO:0043616]; limb morphogenesis [GO:0035108]; liver regeneration [GO:0097421]; mammary gland duct morphogenesis [GO:0060603]; mammary gland epithelial cell differentiation [GO:0060644]; metanephric collecting duct development [GO:0072205]; negative regulation of cell division [GO:0051782]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural plate axis specification [GO:0021997]; neural tube closure [GO:0001843]; neural tube patterning [GO:0021532]; pharyngeal system development [GO:0060037]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epidermal cell differentiation [GO:0045606]; prostate gland development [GO:0030850]; protein localization to plasma membrane [GO:0072659]; protein processing [GO:0016485]; regulation of mitotic cell cycle [GO:0007346]; regulation of protein localization [GO:0032880]; regulation of smoothened signaling pathway [GO:0008589]; response to chlorate [GO:0010157]; response to estradiol [GO:0032355]; response to mechanical stimulus [GO:0009612]; response to retinoic acid [GO:0032526]; response to xenobiotic stimulus [GO:0009410]; smooth muscle tissue development [GO:0048745]; smoothened signaling pathway [GO:0007224]; somite development [GO:0061053]; spermatid development [GO:0007286]; spinal cord motor neuron differentiation [GO:0021522]; stem cell proliferation [GO:0072089] apical part of cell [GO:0045177]; axonal growth cone [GO:0044295]; caveola [GO:0005901]; ciliary membrane [GO:0060170]; dendritic growth cone [GO:0044294]; endocytic vesicle membrane [GO:0030666]; intracellular membrane-bounded organelle [GO:0043231]; midbody [GO:0030496]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] cholesterol binding [GO:0015485]; cyclin binding [GO:0030332]; hedgehog family protein binding [GO:0097108]; hedgehog receptor activity [GO:0008158]; heparin binding [GO:0008201]; patched binding [GO:0005113]; protein-containing complex binding [GO:0044877]; smoothened binding [GO:0005119] 0.95841 -1.8671 ATGRKAPLWLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0938 0 0 0 0 0 0 0 0 0 0 0 Q13642 FHL1_HUMAN Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM-protein 1) (SLIM) (SLIM-1) FHL1 SLIM1 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell differentiation [GO:0030154]; muscle organ development [GO:0007517]; negative regulation of cell growth [GO:0030308]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; positive regulation of potassium ion transport [GO:0043268]; regulation of membrane depolarization [GO:0003254]; regulation of potassium ion transmembrane transporter activity [GO:1901016] cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; plasma membrane [GO:0005886] metal ion binding [GO:0046872]; transmembrane transporter binding [GO:0044325] 0.94556 -1.3411 EVHYKNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.1145 Q13651 I10R1_HUMAN Interleukin-10 receptor subunit alpha (IL-10 receptor subunit alpha) (IL-10R subunit alpha) (IL-10RA) (CDw210a) (Interleukin-10 receptor subunit 1) (IL-10R subunit 1) (IL-10R1) (CD antigen CD210) IL10RA IL10R Homo sapiens (Human) intestinal epithelial structure maintenance [GO:0060729]; negative regulation of autophagy [GO:0010507]; negative regulation of inflammatory response [GO:0050728]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of synapse organization [GO:0050807]; response to lipopolysaccharide [GO:0032496]; ubiquitin-dependent endocytosis [GO:0070086] apical plasma membrane [GO:0016324]; cytosol [GO:0005829]; plasma membrane [GO:0005886] interleukin-10 binding [GO:0019969]; interleukin-10 receptor activity [GO:0004920]; signaling receptor activity [GO:0038023] 0.96888 -3.3761 EYEIAIR 0 0 0 0 0 0 0 0 0 0 8.45376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13671 RIN1_HUMAN Ras and Rab interactor 1 (Ras inhibitor JC99) (Ras interaction/interference protein 1) RIN1 Homo sapiens (Human) endocytosis [GO:0006897]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endocytic vesicle [GO:0030139]; plasma membrane [GO:0005886] GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; small GTPase binding [GO:0031267] 0.84782 0.15748 QCQALCMR 0 0 0 0 0 11.2354 0 0 0 0 0 0 0 0 10.2131 0 0 0 0 0 0 0 0 0 0 0 0 Q13683 ITA7_HUMAN Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form] ITGA7 UNQ406/PRO768 Homo sapiens (Human) cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; endodermal cell differentiation [GO:0035987]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; muscle organ development [GO:0007517]; regulation of cell shape [GO:0008360]; skeletal muscle tissue development [GO:0007519] cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integrin complex [GO:0008305]; plasma membrane [GO:0005886] integrin binding [GO:0005178]; laminin binding [GO:0043236]; metal ion binding [GO:0046872] 0.76301 0.29625 IVTCAHRYEARQR 0 0 0 0 0 0 0 0 0 0 0 10.124 0 0 10.1579 8.65546 0 0 0 0 10.4549 0 0 0 0 0 0 Q13698 CAC1S_HUMAN "Voltage-dependent L-type calcium channel subunit alpha-1S (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle) (Voltage-gated calcium channel subunit alpha Cav1.1)" CACNA1S CACH1 CACN1 CACNL1A3 Homo sapiens (Human) calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cellular response to caffeine [GO:0071313]; endoplasmic reticulum organization [GO:0007029]; extraocular skeletal muscle development [GO:0002074]; muscle contraction [GO:0006936]; myoblast fusion [GO:0007520]; neuromuscular junction development [GO:0007528]; positive regulation of muscle contraction [GO:0045933]; regulation of monoatomic ion transmembrane transport [GO:0034765]; skeletal muscle adaptation [GO:0043501]; skeletal muscle fiber development [GO:0048741]; skeletal system development [GO:0001501]; striated muscle contraction [GO:0006941] cytoplasm [GO:0005737]; I band [GO:0031674]; L-type voltage-gated calcium channel complex [GO:1990454]; plasma membrane [GO:0005886]; sarcoplasmic reticulum [GO:0016529]; T-tubule [GO:0030315]; voltage-gated calcium channel complex [GO:0005891] calmodulin binding [GO:0005516]; high voltage-gated calcium channel activity [GO:0008331]; metal ion binding [GO:0046872]; molecular function activator activity [GO:0140677]; small molecule binding [GO:0036094]; voltage-gated calcium channel activity [GO:0005245] 0.96929 -4.2577 FMKRQEEYYGYRPK 0 0 11.3799 0 0 0 0 8.70394 0 0 0 16.0025 0 15.9615 0 0 0 0 12.8648 0 0 0 12.2782 0 0 11.3653 0 Q13702 RAPSN_HUMAN 43 kDa receptor-associated protein of the synapse (RAPsyn) (43 kDa postsynaptic protein) (Acetylcholine receptor-associated 43 kDa protein) (RING finger protein 205) RAPSN RNF205 Homo sapiens (Human) "chemical synaptic transmission [GO:0007268]; establishment of protein localization to postsynaptic membrane [GO:1903540]; motor neuron apoptotic process [GO:0097049]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; positive regulation of motor neuron apoptotic process [GO:2000673]; positive regulation of neuromuscular synaptic transmission [GO:1900075]; regulation of postsynaptic membrane organization [GO:1901626]; synaptic transmission, cholinergic [GO:0007271]" centrosome [GO:0005813]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; neuromuscular junction [GO:0031594]; plasma membrane [GO:0005886]; postsynaptic specialization membrane [GO:0099634] acetylcholine receptor binding [GO:0033130]; ionotropic glutamate receptor binding [GO:0035255]; metal ion binding [GO:0046872]; protein-membrane adaptor activity [GO:0043495]; structural constituent of postsynaptic specialization [GO:0098879] 0.95116 -1.4133 ALESFEKALR 0 0 0 0 0 0 0 10.9152 0 0 0 0 0 0 0 0 0 0 0 12.8351 0 0 0 0 0 0 0 Q13705 AVR2B_HUMAN Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB) ACVR2B Homo sapiens (Human) activation of protein kinase activity [GO:0032147]; activin receptor signaling pathway [GO:0032924]; anterior/posterior pattern specification [GO:0009952]; artery development [GO:0060840]; blood vessel remodeling [GO:0001974]; BMP signaling pathway [GO:0030509]; cellular response to growth factor stimulus [GO:0071363]; determination of left/right symmetry [GO:0007368]; embryonic foregut morphogenesis [GO:0048617]; gastrulation with mouth forming second [GO:0001702]; heart development [GO:0007507]; insulin secretion [GO:0030073]; kidney development [GO:0001822]; lung development [GO:0030324]; lymphangiogenesis [GO:0001946]; lymphatic endothelial cell differentiation [GO:0060836]; mesoderm development [GO:0007498]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis of dentin-containing tooth [GO:0042475]; organ growth [GO:0035265]; pancreas development [GO:0031016]; positive regulation of activin receptor signaling pathway [GO:0032927]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; post-embryonic development [GO:0009791]; protein phosphorylation [GO:0006468]; regulation of DNA-templated transcription [GO:0006355]; response to glucose [GO:0009749]; retina vasculature development in camera-type eye [GO:0061298]; roof of mouth development [GO:0060021]; signal transduction [GO:0007165]; skeletal system morphogenesis [GO:0048705]; transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178]; venous blood vessel development [GO:0060841] activin receptor complex [GO:0048179]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235] activin binding [GO:0048185]; activin receptor activity [GO:0017002]; ATP binding [GO:0005524]; growth factor binding [GO:0019838]; metal ion binding [GO:0046872]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712] 0.91623 -0.84987 CEGEQDKR 0 0 0 0 0 9.74403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13724 MOGS_HUMAN Mannosyl-oligosaccharide glucosidase (EC 3.2.1.106) (Processing A-glucosidase I) MOGS GCS1 Homo sapiens (Human) oligosaccharide metabolic process [GO:0009311]; protein folding [GO:0006457]; protein N-linked glycosylation [GO:0006487]; viral protein processing [GO:0019082] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; membrane [GO:0016020] Glc3Man9GlcNAc2 oligosaccharide glucosidase activity [GO:0004573]; glucosidase activity [GO:0015926] 0.92403 -1.04 ERFEKTFQLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.99958 0 0 0 0 0 0 0 8.91907 0 Q13733 AT1A4_HUMAN Sodium/potassium-transporting ATPase subunit alpha-4 (Na(+)/K(+) ATPase alpha-4 subunit) (EC 7.2.2.13) (Sodium pump subunit alpha-4) ATP1A4 ATP1AL2 Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; establishment of localization in cell [GO:0051649]; fertilization [GO:0009566]; flagellated sperm motility [GO:0030317]; intracellular potassium ion homeostasis [GO:0030007]; intracellular sodium ion homeostasis [GO:0006883]; monoatomic ion transport [GO:0006811]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; proton transmembrane transport [GO:1902600]; regulation of cellular pH [GO:0030641]; regulation of membrane potential [GO:0042391]; sodium ion export across plasma membrane [GO:0036376]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]; spermatogenesis [GO:0007283]; transport across blood-brain barrier [GO:0150104] cell projection [GO:0042995]; membrane raft [GO:0045121]; photoreceptor cell cilium [GO:0097733]; plasma membrane [GO:0005886]; rod photoreceptor outer segment [GO:0120200]; sodium:potassium-exchanging ATPase complex [GO:0005890]; sperm midpiece [GO:0097225] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled monoatomic cation transmembrane transporter activity [GO:0019829]; kinase binding [GO:0019900]; metal ion binding [GO:0046872]; P-type sodium:potassium-exchanging transporter activity [GO:0005391] 0.8987 -0.58087 IAGLCNRADFK 0 0 0 0 9.10192 0 0 0 0 0 0 0 0 0 0 10.8881 0 0 0 0 0 0 0 0 0 0 0 Q13751 LAMB3_HUMAN Laminin subunit beta-3 (Epiligrin subunit bata) (Kalinin B1 chain) (Kalinin subunit beta) (Laminin B1k chain) (Laminin-5 subunit beta) (Nicein subunit beta) LAMB3 LAMNB1 Homo sapiens (Human) brown fat cell differentiation [GO:0050873]; cell adhesion [GO:0007155]; endodermal cell differentiation [GO:0035987]; epidermis development [GO:0008544] collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; laminin-5 complex [GO:0005610] protein-containing complex binding [GO:0044877]; structural molecule activity [GO:0005198] 0.9598 -1.9401 AGGAFLMAGQVAEQLRGFNAQLQR 0 0 0 0 9.67165 0 0 0 0 0 0 0 0 10.1316 10.0229 11.1807 0 0 0 0 0 0 0 0 0 0 0 Q13753 LAMC2_HUMAN Laminin subunit gamma-2 (Cell-scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Epiligrin subunit gamma) (Kalinin subunit gamma) (Kalinin/nicein/epiligrin 100 kDa subunit) (Ladsin 140 kDa subunit) (Laminin B2t chain) (Laminin-5 subunit gamma) (Large adhesive scatter factor 140 kDa subunit) (Nicein subunit gamma) LAMC2 LAMB2T LAMNB2 Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284] cell cortex [GO:0005938]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; laminin-2 complex [GO:0005607]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471] heparin binding [GO:0008201] 0.92373 -1.0495 EVEGELERK 0 0 0 0 0 0 0 0 0 0 0 10.4414 0 0 0 0 0 0 9.98712 9.4208 0 0 0 0 0 0 0 Q13761 RUNX3_HUMAN Runt-related transcription factor 3 (Acute myeloid leukemia 2 protein) (Core-binding factor subunit alpha-3) (CBF-alpha-3) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEA2-alpha C) (PEBP2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit) RUNX3 AML2 CBFA3 PEBP2A3 Homo sapiens (Human) "hemopoiesis [GO:0030097]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of cell cycle [GO:0045786]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; peripheral nervous system neuron development [GO:0048935]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of DNA-templated transcription [GO:0045893]; protein phosphorylation [GO:0006468]; regulation of cell differentiation [GO:0045595]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; response to transforming growth factor beta [GO:0071559]" chromatin [GO:0000785]; core-binding factor complex [GO:0016513]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "ATP binding [GO:0005524]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription corepressor binding [GO:0001222]" 0.55949 0.51697 IPVDPSTSRR 0 0 0 0 0 0 0 0 0 0 0 10.0711 9.7217 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13769 THOC5_HUMAN THO complex subunit 5 homolog (Functional spliceosome-associated protein 79) (fSAP79) (NF2/meningioma region protein pK1.3) (Placental protein 39.2) (PP39.2) (hTREX90) THOC5 C22orf19 KIAA0983 Homo sapiens (Human) "monocyte differentiation [GO:0030224]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; primitive hemopoiesis [GO:0060215]; RNA splicing [GO:0008380]; viral mRNA export from host cell nucleus [GO:0046784]" cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; THO complex [GO:0000347]; THO complex part of transcription export complex [GO:0000445]; transcription export complex [GO:0000346] mRNA binding [GO:0003729] 0.94493 -1.3417 DQTHEAK 0 0 0 0 0 0 0 0 0 0 0 10.3577 0 0 0 8.88756 0 0 0 0 0 0 0 0 0 0 0 Q13772 NCOA4_HUMAN Nuclear receptor coactivator 4 (NCoA-4) (Androgen receptor coactivator 70 kDa protein) (70 kDa AR-activator) (70 kDa androgen receptor coactivator) (Androgen receptor-associated protein of 70 kDa) (Ret-activating protein ELE1) NCOA4 ARA70 ELE1 RFG Homo sapiens (Human) cellular response to estrogen stimulus [GO:0071391]; cellular response to testosterone stimulus [GO:0071394]; intracellular estrogen receptor signaling pathway [GO:0030520]; intracellular iron ion homeostasis [GO:0006879]; male gonad development [GO:0008584]; protein targeting to lysosome [GO:0006622]; response to hormone [GO:0009725] autolysosome [GO:0044754]; nucleus [GO:0005634] transcription coactivator activity [GO:0003713] 0.8484 0.17129 MNTFQDQSGSSSNR 0 0 0 0 0 0 9.34219 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13796 SHRM2_HUMAN Protein Shroom2 (Apical-like protein) (Protein APXL) SHROOM2 APXL Homo sapiens (Human) actin filament organization [GO:0007015]; apical protein localization [GO:0045176]; brain development [GO:0007420]; camera-type eye development [GO:0043010]; camera-type eye morphogenesis [GO:0048593]; cell migration [GO:0016477]; cellular pigment accumulation [GO:0043482]; ear development [GO:0043583]; establishment of melanosome localization [GO:0032401]; eye pigment granule organization [GO:0008057]; lens morphogenesis in camera-type eye [GO:0002089]; melanosome organization [GO:0032438] adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]; plasma membrane [GO:0005886] actin binding [GO:0003779]; actin filament binding [GO:0051015]; beta-catenin binding [GO:0008013]; ligand-gated sodium channel activity [GO:0015280] 0.96874 -8.1068 AGLGGGTQEGPLAGTYK 0 0 10.5782 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5187 0 9.46084 9.73552 9.87652 10.3067 0 11.3612 Q13797 ITA9_HUMAN Integrin alpha-9 (Integrin alpha-RLC) ITGA9 Homo sapiens (Human) cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; integrin-mediated signaling pathway [GO:0007229]; neutrophil chemotaxis [GO:0030593] basal plasma membrane [GO:0009925]; external side of plasma membrane [GO:0009897]; integrin complex [GO:0008305]; plasma membrane [GO:0005886] integrin binding [GO:0005178]; metal ion binding [GO:0046872] 0.90756 -0.7118 LNDEVIMNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.76623 8.68541 0 0 0 Q13813 SPTN1_HUMAN "Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)" SPTAN1 NEAS SPTA2 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament capping [GO:0051693] cell junction [GO:0030054]; cell projection [GO:0042995]; cortical actin cytoskeleton [GO:0030864]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular vesicle [GO:1903561]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; plasma membrane [GO:0005886]; specific granule lumen [GO:0035580]; spectrin [GO:0008091]; tertiary granule lumen [GO:1904724] actin binding [GO:0003779]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; structural constituent of cytoskeleton [GO:0005200] 0.007874 2.0527 AALLELWELRR 0 9.78341 0 0 0 0 0 8.15122 0 0 0 9.50853 0 0 0 0 0 8.44099 0 10.3996 8.69742 0 0 0 12.8135 0 0 Q13822 ENPP2_HUMAN Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (E-NPP 2) (EC 3.1.4.39) (Autotaxin) (Extracellular lysophospholipase D) (LysoPLD) ENPP2 ATX PDNP2 Homo sapiens (Human) cell motility [GO:0048870]; chemotaxis [GO:0006935]; immune response [GO:0006955]; phosphatidylcholine catabolic process [GO:0034638]; phospholipid catabolic process [GO:0009395]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell migration [GO:0030334]; sphingolipid catabolic process [GO:0030149] extracellular space [GO:0005615]; plasma membrane [GO:0005886] alkylglycerophosphoethanolamine phosphodiesterase activity [GO:0047391]; calcium ion binding [GO:0005509]; hydrolase activity [GO:0016787]; lysophospholipase activity [GO:0004622]; nucleic acid binding [GO:0003676]; phosphodiesterase I activity [GO:0004528]; polysaccharide binding [GO:0030247]; scavenger receptor activity [GO:0005044]; zinc ion binding [GO:0008270] 0.96381 -2.2382 FNHRWWGGQPLWITATK 0 0 0 0 0 0 0 0 9.42666 0 0 0 0 0 0 0 0 0 0 0 0 9.34713 0 0 0 0 0 Q13823 NOG2_HUMAN Nucleolar GTP-binding protein 2 (Autoantigen NGP-1) GNL2 NGP1 Homo sapiens (Human) ribosome biogenesis [GO:0042254] membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; RNA binding [GO:0003723] 0.40919 0.69245 HLIFVLNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.8334 0 0 0 0 0 0 0 0 0 0 0 0 Q13829 BACD2_HUMAN "BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (hBACURD2) (BTB/POZ domain-containing protein TNFAIP1) (Protein B12) (Tumor necrosis factor, alpha-induced protein 1, endothelial)" TNFAIP1 BACURD2 EDP1 Homo sapiens (Human) apoptotic process [GO:0006915]; cell migration [GO:0016477]; immune response [GO:0006955]; negative regulation of Rho protein signal transduction [GO:0035024]; positive regulation of DNA replication [GO:0045740]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; stress fiber assembly [GO:0043149] Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleus [GO:0005634] cyclin binding [GO:0030332]; identical protein binding [GO:0042802]; small GTPase binding [GO:0031267] 0.96946 -7.3979 GGGLGNK 10.8435 10.1226 0 9.04117 9.16862 9.16639 11.1517 11.064 10.8003 10.9454 11.3448 11.3106 11.331 11.2827 10.9799 11.6965 11.9424 11.7055 11.4136 11.355 11.8161 10.8467 10.8543 10.7393 13.4639 13.2933 13.2031 Q13838 DX39B_HUMAN Spliceosome RNA helicase DDX39B (EC 3.6.4.13) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (DEAD box protein UAP56) (HLA-B-associated transcript 1 protein) DDX39B BAT1 UAP56 Homo sapiens (Human) "mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; RNA export from nucleus [GO:0006405]; RNA secondary structure unwinding [GO:0010501]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245]; viral mRNA export from host cell nucleus [GO:0046784]" cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; transcription export complex [GO:0000346]; U4 snRNP [GO:0005687]; U6 snRNP [GO:0005688] "ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent activity, acting on RNA [GO:0008186]; ATP-dependent protein binding [GO:0043008]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; U4 snRNA binding [GO:0030621]; U6 snRNA binding [GO:0017070]" 0.0078534 2.0508 DVQEIFR 0 0 0 0 0 0 0 10.1558 0 0 0 0 0 0 0 0 10.688 0 9.96172 8.58845 0 9.43187 0 0 12.0832 12.6779 0 Q13868 EXOS2_HUMAN Exosome complex component RRP4 (Exosome component 2) (Ribosomal RNA-processing protein 4) EXOSC2 RRP4 Homo sapiens (Human) "CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; positive regulation of cell growth [GO:0030307]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; rRNA processing [GO:0006364]; U4 snRNA 3'-end processing [GO:0034475]" cytoplasm [GO:0005737]; cytoplasmic exosome (RNase complex) [GO:0000177]; cytosol [GO:0005829]; exosome (RNase complex) [GO:0000178]; nuclear exosome (RNase complex) [GO:0000176]; nucleolar exosome (RNase complex) [GO:0101019]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 3'-5'-RNA exonuclease activity [GO:0000175]; 7S RNA binding [GO:0008312]; RNA binding [GO:0003723] 0.78682 0.25775 GHGTYMGEEK 0 0 0 0 0 0 0 8.84266 0 9.42953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13873 BMPR2_HUMAN Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II) BMPR2 PPH1 Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; aortic valve development [GO:0003176]; artery development [GO:0060840]; atrial septum morphogenesis [GO:0060413]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; BMP signaling pathway [GO:0030509]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; cellular response to starvation [GO:0009267]; chondrocyte development [GO:0002063]; endocardial cushion development [GO:0003197]; endochondral bone morphogenesis [GO:0060350]; endothelial cell apoptotic process [GO:0072577]; endothelial cell proliferation [GO:0001935]; limb development [GO:0060173]; lung alveolus development [GO:0048286]; lymphangiogenesis [GO:0001946]; lymphatic endothelial cell differentiation [GO:0060836]; maternal placenta development [GO:0001893]; mesoderm formation [GO:0001707]; mitral valve morphogenesis [GO:0003183]; negative regulation of cell growth [GO:0030308]; negative regulation of cell proliferation involved in heart valve morphogenesis [GO:0003252]; negative regulation of chondrocyte proliferation [GO:1902731]; negative regulation of DNA biosynthetic process [GO:2000279]; negative regulation of muscle cell differentiation [GO:0051148]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of systemic arterial blood pressure [GO:0003085]; negative regulation of vasoconstriction [GO:0045906]; osteoblast differentiation [GO:0001649]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; pharyngeal arch artery morphogenesis [GO:0061626]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cartilage development [GO:0061036]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of gene expression [GO:0010628]; positive regulation of ossification [GO:0045778]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; proteoglycan biosynthetic process [GO:0030166]; pulmonary valve development [GO:0003177]; regulation of cell population proliferation [GO:0042127]; regulation of lung blood pressure [GO:0014916]; retina vasculature development in camera-type eye [GO:0061298]; semi-lunar valve development [GO:1905314]; transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178]; tricuspid valve morphogenesis [GO:0003186]; venous blood vessel development [GO:0060841]; ventricular septum morphogenesis [GO:0060412] adherens junction [GO:0005912]; axon [GO:0030424]; cell body [GO:0044297]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; dendrite [GO:0030425]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; receptor complex [GO:0043235] "activin receptor activity, type II [GO:0016362]; ATP binding [GO:0005524]; BMP binding [GO:0036122]; BMP receptor activity [GO:0098821]; cadherin binding [GO:0045296]; kinase activator activity [GO:0019209]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein tyrosine kinase binding [GO:1990782]; transforming growth factor beta receptor activity [GO:0005024]" 0.95296 -1.4799 LDPKEVDK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.68336 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13875 MOBP_HUMAN Myelin-associated oligodendrocyte basic protein MOBP Homo sapiens (Human) central nervous system myelin formation [GO:0032289]; nervous system development [GO:0007399] mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471] structural constituent of myelin sheath [GO:0019911] 0.80944 0.23259 QQPAAPPAVVR 12.5679 0 12.3204 0 8.62852 0 12.2972 12.467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13882 PTK6_HUMAN Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK) PTK6 BRK Homo sapiens (Human) cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to retinoic acid [GO:0071300]; ERBB2 signaling pathway [GO:0038128]; innate immune response [GO:0045087]; intestinal epithelial cell differentiation [GO:0060575]; negative regulation of growth [GO:0045926]; negative regulation of protein tyrosine kinase activity [GO:0061099]; positive regulation of cell cycle [GO:0045787]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of neuron projection development [GO:0010976]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; tyrosine phosphorylation of STAT protein [GO:0007260] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ruffle [GO:0001726] ATP binding [GO:0005524]; identical protein binding [GO:0042802]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102] 0.87924 0.018151 EDVYLSHDHNIPYK 0 0 0 0 0 0 0 0 8.79435 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13887 KLF5_HUMAN Krueppel-like factor 5 (Basic transcription element-binding protein 2) (BTE-binding protein 2) (Colon krueppel-like factor) (GC-box-binding protein 2) (Intestinal-enriched krueppel-like factor) (Transcription factor BTEB2) KLF5 BTEB2 CKLF IKLF Homo sapiens (Human) angiogenesis [GO:0001525]; cell-cell signaling via exosome [GO:0099156]; cellular response to leukemia inhibitory factor [GO:1990830]; intestinal epithelial cell development [GO:0060576]; microvillus assembly [GO:0030033]; myotube differentiation involved in skeletal muscle regeneration [GO:0014908]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by transcription factor localization [GO:0061586]; regulation of microvillus assembly [GO:0032534]; regulation of transcription by RNA polymerase II [GO:0006357]; satellite cell activation involved in skeletal muscle regeneration [GO:0014901]; skeletal muscle satellite cell differentiation [GO:0014816] chromatin [GO:0000785]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; transcription regulator complex [GO:0005667] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; MRF binding [GO:0043426]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.80095 0.23938 DAALFPGEELK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.22345 0 0 0 0 0 0 0 0 0 0 0 0 Q13889 TF2H3_HUMAN General transcription factor IIH subunit 3 (Basic transcription factor 2 34 kDa subunit) (BTF2 p34) (General transcription factor IIH polypeptide 3) (TFIIH basal transcription factor complex p34 subunit) GTF2H3 Homo sapiens (Human) DNA repair [GO:0006281]; nucleotide-excision repair [GO:0006289]; regulation of DNA-templated transcription [GO:0006355]; transcription by RNA polymerase II [GO:0006366] core TFIIH complex portion of holo TFIIH complex [GO:0000438]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIH core complex [GO:0000439]; transcription factor TFIIH holo complex [GO:0005675]; transcription preinitiation complex [GO:0097550] metal ion binding [GO:0046872]; RNA polymerase II general transcription initiation factor activity [GO:0016251] 0.88558 -0.38478 ALCYIHRMNKEVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2687 0 0 Q13895 BYST_HUMAN Bystin BYSL ENP1 Homo sapiens (Human) "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; regulation of protein localization to nucleolus [GO:1904749]; ribosome biogenesis [GO:0042254]; rRNA processing [GO:0006364]; stem cell proliferation [GO:0072089]; trophectodermal cell differentiation [GO:0001829]" "apical part of cell [GO:0045177]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; preribosome, small subunit precursor [GO:0030688]" RNA binding [GO:0003723]; snoRNA binding [GO:0030515] 0.88373 -0.3285 VRDDVAEYK 0 0 0 0 0 0 0 0 0 0 0 8.89333 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13901 C1D_HUMAN Nuclear nucleic acid-binding protein C1D (hC1D) C1D Homo sapiens (Human) apoptotic process [GO:0006915]; maturation of 5.8S rRNA [GO:0000460]; regulation of gene expression [GO:0010468] cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; nuclear exosome (RNase complex) [GO:0000176]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription repressor complex [GO:0017053] DNA binding [GO:0003677]; nuclear receptor binding [GO:0016922]; RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714] 0.84882 0.16405 LDPLEQAK 0 0 0 0 10.331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13905 RPGF1_HUMAN Rap guanine nucleotide exchange factor 1 (CRK SH3-binding GNRP) (Guanine nucleotide-releasing factor 2) (Protein C3G) RAPGEF1 GRF2 Homo sapiens (Human) cellular response to cAMP [GO:0071320]; cellular response to nerve growth factor stimulus [GO:1990090]; establishment of endothelial barrier [GO:0061028]; nerve growth factor signaling pathway [GO:0038180]; nervous system development [GO:0007399]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron projection development [GO:0010976]; Rap protein signal transduction [GO:0032486]; Ras protein signal transduction [GO:0007265]; regulation of cell junction assembly [GO:1901888]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886] guanyl-nucleotide exchange factor activity [GO:0005085]; SH3 domain binding [GO:0017124] 0.88221 -0.084467 EVVSALRYFKTIVDK 0 0 0 0 0 0 0 0 0 0 0 12.3255 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13907 IDI1_HUMAN Isopentenyl-diphosphate Delta-isomerase 1 (EC 5.3.3.2) (Isopentenyl pyrophosphate isomerase 1) (IPP isomerase 1) (IPPI1) IDI1 Homo sapiens (Human) cholesterol biosynthetic process [GO:0006695]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299] cytoplasm [GO:0005737]; cytosol [GO:0005829]; peroxisome [GO:0005777] isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872] 0.90543 -0.72839 SYCYVSKEELK 0 0 0 0 0 0 0 0 8.95376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13936 CAC1C_HUMAN "Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Voltage-gated calcium channel subunit alpha Cav1.2)" CACNA1C CACH2 CACN2 CACNL1A1 CCHL1A1 Homo sapiens (Human) calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transmembrane transport via high voltage-gated calcium channel [GO:0061577]; calcium ion transport into cytosol [GO:0060402]; calcium-mediated signaling using extracellular calcium source [GO:0035585]; camera-type eye development [GO:0043010]; cardiac conduction [GO:0061337]; cardiac muscle cell action potential involved in contraction [GO:0086002]; cell communication by electrical coupling involved in cardiac conduction [GO:0086064]; embryonic forelimb morphogenesis [GO:0035115]; heart development [GO:0007507]; immune system development [GO:0002520]; membrane depolarization during atrial cardiac muscle cell action potential [GO:0098912]; membrane depolarization during AV node cell action potential [GO:0086045]; membrane depolarization during cardiac muscle cell action potential [GO:0086012]; positive regulation of adenylate cyclase activity [GO:0045762]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ventricular cardiac muscle cell action potential [GO:0098911] cytoplasm [GO:0005737]; dendrite [GO:0030425]; L-type voltage-gated calcium channel complex [GO:1990454]; membrane [GO:0016020]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018] alpha-actinin binding [GO:0051393]; calmodulin binding [GO:0005516]; high voltage-gated calcium channel activity [GO:0008331]; metal ion binding [GO:0046872]; voltage-gated calcium channel activity [GO:0005245]; voltage-gated calcium channel activity involved in AV node cell action potential [GO:0086056]; voltage-gated calcium channel activity involved in cardiac muscle cell action potential [GO:0086007] 0.93907 -1.2962 GAGFDVK 0 0 0 0 0 0 0 0 0 0 0 10.6944 0 0 0 0 0 8.53664 0 0 0 0 0 0 0 0 0 Q13939 CALI_HUMAN Calicin CCIN Homo sapiens (Human) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] cytoskeletal calyx [GO:0033150]; nucleus [GO:0005634] 0.94023 -1.3026 YVSNIYRYDERK 0 0 0 0 0 0 0 0 0 0 0 0 9.96142 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q13972 RGRF1_HUMAN Ras-specific guanine nucleotide-releasing factor 1 (Ras-GRF1) (Guanine nucleotide-releasing protein) (GNRP) (Ras-specific nucleotide exchange factor CDC25) RASGRF1 CDC25 GNRP GRF1 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; long-term memory [GO:0007616]; neuron projection development [GO:0031175]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Ras protein signal transduction [GO:0046579]; Ras protein signal transduction [GO:0007265]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of NMDA receptor activity [GO:2000310]; regulation of Rac protein signal transduction [GO:0035020]; regulation of Ras protein signal transduction [GO:0046578]; regulation of synaptic plasticity [GO:0048167]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; type B pancreatic cell proliferation [GO:0044342] cytosol [GO:0005829]; growth cone [GO:0030426]; neuron projection [GO:0043005]; plasma membrane [GO:0005886] glutamate receptor binding [GO:0035254]; guanyl-nucleotide exchange factor activity [GO:0005085] 0.95822 -1.6841 ALELRTEDAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.5205 0 0 0 0 10.4277 0 Q13976 KGP1_HUMAN cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI) PRKG1 PRKG1B PRKGR1A PRKGR1B Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; collateral sprouting [GO:0048668]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular associated smooth muscle [GO:0060087]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310] 0.96961 -4.0081 GIDMIEFPK 0 11.4412 0 0 0 0 0 10.9574 0 0 0 0 0 0 0 0 10.6304 10.8901 10.0441 0 0 0 0 0 13.201 0 10.2458 Q14004 CDK13_HUMAN Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller) CDK13 CDC2L CDC2L5 CHED KIAA1791 Homo sapiens (Human) "alternative mRNA splicing, via spliceosome [GO:0000380]; hemopoiesis [GO:0030097]; negative regulation of stem cell differentiation [GO:2000737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; protein phosphorylation [GO:0006468]; regulation of signal transduction [GO:0009966]" cyclin K-CDK13 complex [GO:0002945]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; Golgi apparatus [GO:0005794]; nuclear cyclin-dependent protein kinase holoenzyme complex [GO:0019908]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine kinase activity [GO:0106310]; RNA binding [GO:0003723]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353] 0.95912 -1.831 ERHREHR 0 9.78341 0 9.60857 9.40678 9.49679 10.9172 0 11.1537 10.3847 0 0 0 11.5404 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14008 CKAP5_HUMAN Cytoskeleton-associated protein 5 (Colonic and hepatic tumor overexpressed gene protein) (Ch-TOG) CKAP5 KIAA0097 Homo sapiens (Human) cell division [GO:0051301]; centrosome cycle [GO:0007098]; centrosome duplication [GO:0051298]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; microtubule depolymerization [GO:0007019]; microtubule polymerization [GO:0046785]; mitotic spindle organization [GO:0007052]; positive regulation of microtubule nucleation [GO:0090063]; RNA transport [GO:0050658]; spindle organization [GO:0007051] centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; membrane [GO:0016020]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; spindle pole [GO:0000922] cadherin binding [GO:0045296]; microtubule binding [GO:0008017]; microtubule plus end polymerase [GO:0061863]; microtubule plus-end binding [GO:0051010]; ribonucleoprotein complex binding [GO:0043021] 0.96993 -3.2756 AGGPPKK 9.51712 9.59909 10.1459 0 0 0 0 9.48824 9.54115 10.0249 9.93915 9.72223 8.54307 0 0 0 0 0 0 0 0 0 0 0 0 0 8.83434 Q14011 CIRBP_HUMAN Cold-inducible RNA-binding protein (A18 hnRNP) (Glycine-rich RNA-binding protein CIRP) CIRBP A18HNRNP CIRP Homo sapiens (Human) "mRNA stabilization [GO:0048255]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of translation [GO:0045727]; response to cold [GO:0009409]; response to UV [GO:0009411]; stress granule assembly [GO:0034063]" cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681] mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; small ribosomal subunit rRNA binding [GO:0070181]; translation repressor activity [GO:0030371] 0.67191 0.39371 GGSAGGR 0 0 0 0 0 0 0 0 0 0 0 9.77868 0 8.99492 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14012 KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) CAMK1 Homo sapiens (Human) cell cycle [GO:0007049]; cell differentiation [GO:0030154]; negative regulation of protein binding [GO:0032091]; nervous system development [GO:0007399]; nucleocytoplasmic transport [GO:0006913]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of synapse structural plasticity [GO:0051835]; positive regulation of syncytium formation by plasma membrane fusion [GO:0060143]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of muscle cell differentiation [GO:0051147]; regulation of protein binding [GO:0043393]; regulation of protein localization [GO:0032880]; signal transduction [GO:0007165] cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; nucleus [GO:0005634]; postsynaptic density [GO:0014069] ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; protein serine kinase activity [GO:0106310] 0.94793 -1.3598 LGAVEGPRWKQAEDIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2156 0 0 0 0 0 0 Q14019 COTL1_HUMAN Coactosin-like protein COTL1 CLP Homo sapiens (Human) defense response to fungus [GO:0050832]; regulation of actin filament polymerization [GO:0030833] cortical actin cytoskeleton [GO:0030864]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; site of polarized growth [GO:0030427] actin binding [GO:0003779]; actin filament binding [GO:0051015]; enzyme binding [GO:0019899] 0.41574 0.68184 AAYNLVR 0 0 0 0 0 0 0 0 0 10.9568 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14028 CNGB1_HUMAN Cyclic nucleotide-gated cation channel beta-1 (Cyclic nucleotide-gated cation channel 4) (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel gamma) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel beta-1) (CNG channel beta-1) (Glutamic acid-rich protein) (GARP) CNGB1 CNCG2 CNCG3L CNCG4 RCNC2 Homo sapiens (Human) "detection of chemical stimulus involved in sensory perception of smell [GO:0050911]; detection of light stimulus involved in visual perception [GO:0050908]; ion channel modulating, G protein-coupled receptor signaling pathway [GO:0099105]; membrane depolarization [GO:0051899]; monoatomic cation transmembrane transport [GO:0098655]; monoatomic cation transport [GO:0006812]; olfactory nerve maturation [GO:0021630]; photoreceptor cell maintenance [GO:0045494]; photoreceptor cell outer segment organization [GO:0035845]; phototransduction [GO:0007602]; positive regulation of gene expression [GO:0010628]; protein localization to organelle [GO:0033365]; response to odorant [GO:1990834]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]" ciliary membrane [GO:0060170]; Golgi-associated vesicle membrane [GO:0030660]; intracellular cyclic nucleotide activated cation channel complex [GO:0017071]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; transmembrane transporter complex [GO:1902495] cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; intracellular cAMP-activated cation channel activity [GO:0005222]; intracellular cGMP-activated cation channel activity [GO:0005223]; ligand-gated monoatomic ion channel activity [GO:0015276]; protein-containing complex binding [GO:0044877] 0.95733 -1.6563 AKEEAEEVAEEEAEK 9.16141 0 0 0 11.4794 11.7607 0 0 0 0 0 0 9.39354 0 12.5524 0 0 12.7093 0 0 8.67423 0 0 0 9.49444 0 0 Q14031 CO4A6_HUMAN Collagen alpha-6(IV) chain COL4A6 Homo sapiens (Human) cell adhesion [GO:0007155]; cellular response to amino acid stimulus [GO:0071230]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; extracellular matrix organization [GO:0030198] basement membrane [GO:0005604]; collagen type IV trimer [GO:0005587]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615] extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020] 0.96768 -3.6984 AGTPGEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.67303 0 0 0 0 0 0 0 8.38823 0 0 0 Q14032 BAAT_HUMAN Bile acid-CoA:amino acid N-acyltransferase (BACAT) (BAT) (EC 2.3.1.65) (Bile acid-CoA thioesterase) (Choloyl-CoA hydrolase) (EC 3.1.2.27) (Glycine N-choloyltransferase) (Long-chain fatty-acyl-CoA hydrolase) (EC 3.1.2.2) BAAT Homo sapiens (Human) acyl-CoA metabolic process [GO:0006637]; animal organ regeneration [GO:0031100]; bile acid biosynthetic process [GO:0006699]; bile acid conjugation [GO:0002152]; bile acid metabolic process [GO:0008206]; fatty acid metabolic process [GO:0006631]; glycine metabolic process [GO:0006544]; liver development [GO:0001889]; taurine metabolic process [GO:0019530] cytosol [GO:0005829]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777] acyl-CoA hydrolase activity [GO:0047617]; acyltransferase activity [GO:0016746]; carboxylic ester hydrolase activity [GO:0052689]; choloyl-CoA hydrolase activity [GO:0033882]; glycine N-choloyltransferase activity [GO:0047963]; long-chain acyl-CoA hydrolase activity [GO:0052816]; medium-chain acyl-CoA hydrolase activity [GO:0052815]; myristoyl-CoA hydrolase activity [GO:0102991]; N-acyltransferase activity [GO:0016410]; palmitoyl-CoA hydrolase activity [GO:0016290]; very long chain acyl-CoA hydrolase activity [GO:0052817] 0.62955 0.40221 ASLTLER 0 0 0 0 0 0 10.1722 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14050 CO9A3_HUMAN Collagen alpha-3(IX) chain COL9A3 Homo sapiens (Human) extracellular matrix organization [GO:0030198] collagen type IX trimer [GO:0005594]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020]; protein homodimerization activity [GO:0042803] 0.56 0.52093 DGQNGVPGLDGQK 0 10.4841 0 0 0 0 0 0 0 0 0 0 0 0 8.22694 0 0 0 8.44692 8.43354 0 0 8.66245 0 0 0 0 Q14088 RB33A_HUMAN Ras-related protein Rab-33A (Small GTP-binding protein S10) RAB33A RABS10 Homo sapiens (Human) antigen processing and presentation [GO:0019882]; Rab protein signal transduction [GO:0032482] endosome [GO:0005768]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886] GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.92375 -1.0105 FCGGTFPDK 9.50395 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.93814 0 0 0 0 0 0 0 0 0 0 Q14093 CYLC2_HUMAN Cylicin-2 (Cylicin II) (Multiple-band polypeptide II) CYLC2 CYL2 Homo sapiens (Human) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] cytoskeletal calyx [GO:0033150]; nucleus [GO:0005634] structural constituent of cytoskeleton [GO:0005200] 0.91527 -0.79429 DIEKGKEEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.36717 0 0 0 0 0 0 Q14094 CCNI_HUMAN Cyclin-I CCNI Homo sapiens (Human) mitotic cell cycle phase transition [GO:0044772]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; spermatogenesis [GO:0007283] cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; nuclear membrane [GO:0031965]; nucleus [GO:0005634] cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538] 0.92731 -1.2019 AITREAQMWK 9.15294 9.06188 0 9.81242 0 9.56226 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14103 HNRPD_HUMAN Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1) HNRNPD AUF1 HNRPD Homo sapiens (Human) "3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to amino acid stimulus [GO:0071230]; cellular response to estradiol stimulus [GO:0071392]; cellular response to nitric oxide [GO:0071732]; cellular response to putrescine [GO:1904586]; cerebellum development [GO:0021549]; circadian regulation of translation [GO:0097167]; CRD-mediated mRNA stabilization [GO:0070934]; hepatocyte dedifferentiation [GO:1990828]; liver development [GO:0001889]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of telomerase RNA reverse transcriptase activity [GO:1905663]; positive regulation of telomere capping [GO:1904355]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of telomere maintenance [GO:0032204]; response to calcium ion [GO:0051592]; response to electrical stimulus [GO:0051602]; response to rapamycin [GO:1901355]; response to sodium phosphate [GO:1904383]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]" cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; mCRD-mediated mRNA stability complex [GO:0106002]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; ribonucleoprotein complex [GO:1990904] chromatin binding [GO:0003682]; histone deacetylase binding [GO:0042826]; minor groove of adenine-thymine-rich DNA binding [GO:0003680]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; RNA binding [GO:0003723]; telomeric DNA binding [GO:0042162] 0.050314 1.4183 DLKDYFSK 0 0 0 0 0 0 9.06059 0 0 0 9.56352 9.40606 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1366 0 Q14108 SCRB2_HUMAN Lysosome membrane protein 2 (85 kDa lysosomal membrane sialoglycoprotein) (LGP85) (CD36 antigen-like 2) (Lysosome membrane protein II) (LIMP II) (Scavenger receptor class B member 2) (CD antigen CD36) SCARB2 CD36L2 LIMP2 LIMPII Homo sapiens (Human) aminophospholipid transport [GO:0015917]; gene expression [GO:0010467]; positive regulation of neuron projection development [GO:0010976]; protein targeting to lysosome [GO:0006622]; receptor-mediated endocytosis [GO:0006898]; regulation of carbohydrate catabolic process [GO:0043470]; regulation of endosome organization [GO:1904978]; regulation of glucosylceramidase activity [GO:1905123]; regulation of lysosome organization [GO:1905671]; sensory perception of sound [GO:0007605] clathrin-coated endocytic vesicle membrane [GO:0030669]; cytoplasm [GO:0005737]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; late endosome membrane [GO:0031902]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886] cargo receptor activity [GO:0038024]; cholesterol binding [GO:0015485]; enzyme binding [GO:0019899]; phosphatidylcholine binding [GO:0031210]; phosphatidylserine binding [GO:0001786]; protein homodimerization activity [GO:0042803]; protein-folding chaperone binding [GO:0051087]; scavenger receptor activity [GO:0005044]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618] 0.091082 1.2094 VEEVGPYTYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.32012 0 0 9.53004 0 0 0 Q14114 LRP8_HUMAN Low-density lipoprotein receptor-related protein 8 (LRP-8) (Apolipoprotein E receptor 2) LRP8 APOER2 Homo sapiens (Human) ammon gyrus development [GO:0021541]; cellular response to cholesterol [GO:0071397]; cellular response to growth factor stimulus [GO:0071363]; chemical synaptic transmission [GO:0007268]; cytokine-mediated signaling pathway [GO:0019221]; dendrite morphogenesis [GO:0048813]; endocytosis [GO:0006897]; layer formation in cerebral cortex [GO:0021819]; lipid metabolic process [GO:0006629]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of dendrite development [GO:1900006]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein tyrosine kinase activity [GO:0061098]; proteolysis [GO:0006508]; reelin-mediated signaling pathway [GO:0038026]; regulation of apoptotic process [GO:0042981]; regulation of innate immune response [GO:0045088]; response to xenobiotic stimulus [GO:0009410]; retinoid metabolic process [GO:0001523]; signal transduction [GO:0007165]; ventral spinal cord development [GO:0021517] axon [GO:0030424]; caveola [GO:0005901]; cell surface [GO:0009986]; dendrite [GO:0030425]; extracellular space [GO:0005615]; membrane [GO:0016020]; microtubule associated complex [GO:0005875]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; receptor complex [GO:0043235] amyloid-beta binding [GO:0001540]; apolipoprotein binding [GO:0034185]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; cargo receptor activity [GO:0038024]; high-density lipoprotein particle binding [GO:0008035]; kinesin binding [GO:0019894]; low-density lipoprotein particle receptor activity [GO:0005041]; reelin receptor activity [GO:0038025]; transmembrane signaling receptor activity [GO:0004888]; very-low-density lipoprotein particle receptor activity [GO:0030229] 0.96414 -2.2693 CDEDDDCLDHSDEDDCPK 0 0 0 0 0 0 0 0 0 0 8.52113 0 0 0 0 0 0 0 0 0 0 12.8601 0 0 0 0 0 Q14117 DPYS_HUMAN Dihydropyrimidinase (DHP) (DHPase) (EC 3.5.2.2) (Dihydropyrimidine amidohydrolase) (Hydantoinase) DPYS Homo sapiens (Human) CMP catabolic process [GO:0006248]; dCMP catabolic process [GO:0006249]; dUMP catabolic process [GO:0046079]; pyrimidine nucleobase catabolic process [GO:0006208]; thymine catabolic process [GO:0006210]; UMP catabolic process [GO:0046050]; uracil catabolic process [GO:0006212] cytosol [GO:0005829]; extracellular exosome [GO:0070062] dihydropyrimidinase activity [GO:0004157]; identical protein binding [GO:0042802]; phosphoprotein binding [GO:0051219]; zinc ion binding [GO:0008270] 0.91515 -0.79094 DLYMVTDLELYEAFSRCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.703 0 0 0 0 0 0 0 0 Q14119 VEZF1_HUMAN Vascular endothelial zinc finger 1 (Putative transcription factor DB1) (Zinc finger protein 161) VEZF1 DB1 ZNF161 Homo sapiens (Human) angiogenesis [GO:0001525]; cellular defense response [GO:0006968]; endothelial cell development [GO:0001885]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.90523 -0.72091 NHACEMCGK 0 8.51369 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.4177 0 0 0 0 0 0 0 0 Q14123 PDE1C_HUMAN "Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Cam-PDE 1C) (EC 3.1.4.17) (Hcam3)" PDE1C Homo sapiens (Human) signal transduction [GO:0007165] cytosol [GO:0005829]; lysosome [GO:0005764]; neuronal cell body [GO:0043025] "3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calmodulin binding [GO:0005516]; calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity [GO:0048101]; calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004117]; metal ion binding [GO:0046872]" 0.88239 -0.077622 IQNISHNWNRK 9.68998 0 0 0 0 0 0 0 0 0 0 0 0 9.42368 0 0 0 0 0 0 0 0 0 0 0 8.76643 8.45705 Q14126 DSG2_HUMAN Desmoglein-2 (Cadherin family member 5) (HDGC) DSG2 CDHF5 Homo sapiens (Human) bundle of His cell-Purkinje myocyte adhesion involved in cell communication [GO:0086073]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; desmosome organization [GO:0002934]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; Purkinje myocyte development [GO:0003165]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ventricular cardiac muscle cell action potential [GO:0098911] cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; cornified envelope [GO:0001533]; desmosome [GO:0030057]; extracellular exosome [GO:0070062]; intercalated disc [GO:0014704]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication [GO:0086083] 0.96978 -3.1097 IHSDLAEER 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4163 0 0 0 0 0 0 0 0 0 0 0 0 9.72137 Q14134 TRI29_HUMAN Tripartite motif-containing protein 29 (Ataxia telangiectasia group D-associated protein) TRIM29 ATDC Homo sapiens (Human) innate immune response [GO:0045087]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122] adherens junction [GO:0005912]; lysosome [GO:0005764] cadherin binding involved in cell-cell adhesion [GO:0098641]; identical protein binding [GO:0042802]; p53 binding [GO:0002039]; zinc ion binding [GO:0008270] 0.95188 -1.3937 DHQLLEPIRDFEAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.49903 0 0 0 Q14135 VGLL4_HUMAN Transcription cofactor vestigial-like protein 4 (Vgl-4) VGLL4 KIAA0121 Homo sapiens (Human) negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell growth [GO:0030308]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hippo signaling [GO:0035331]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of protein catabolic process [GO:0045732] nucleus [GO:0005634] transcription coactivator binding [GO:0001223] 0.96971 -4.167 DPRERSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.39013 0 0 Q14140 SRTD2_HUMAN SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2) SERTAD2 KIAA0127 TRIPBR2 Homo sapiens (Human) negative regulation of cell growth [GO:0030308] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] transcription coactivator activity [GO:0003713] 0.58127 0.47112 IVSPCDGPSK 8.74113 0 0 0 0 0 10.1923 0 0 0 0 11.9157 10.6219 0 0 0 9.98854 10.1202 0 0 0 0 0 0 0 0 0 Q14141 SEPT6_HUMAN Septin-6 SEPTIN6 KIAA0128 SEP2 SEPT6 Homo sapiens (Human) cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; cytoskeleton-dependent cytokinesis [GO:0061640]; mitotic cytokinesis [GO:0000281]; spermatogenesis [GO:0007283] axon terminus [GO:0043679]; cell division site [GO:0032153]; cleavage furrow [GO:0032154]; kinetochore [GO:0000776]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; septin collar [GO:0032173]; septin complex [GO:0031105]; septin ring [GO:0005940]; sperm annulus [GO:0097227]; spindle [GO:0005819]; synaptic vesicle [GO:0008021] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; molecular adaptor activity [GO:0060090] 0.96903 -6.6572 CKLEEMGFK 0 0 0 0 10.4505 0 0 0 0 0 11.4165 0 0 0 0 0 11.7358 0 0 0 0 0 0 0 10.1166 0 0 Q14145 KEAP1_HUMAN Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (INrf2) (Kelch-like protein 19) KEAP1 INRF2 KIAA0132 KLHL19 Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to oxidative stress [GO:0034599]; cytoplasmic sequestering of transcription factor [GO:0042994]; in utero embryonic development [GO:0001701]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein ubiquitination [GO:0016567]; regulation of autophagy [GO:0010506]; regulation of epidermal cell differentiation [GO:0045604]; ubiquitin-dependent protein catabolic process [GO:0006511] actin filament [GO:0005884]; centriolar satellite [GO:0034451]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; inclusion body [GO:0016234]; midbody [GO:0030496]; nucleoplasm [GO:0005654] disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription regulator inhibitor activity [GO:0140416]; ubiquitin ligase-substrate adaptor activity [GO:1990756] 0.7843 0.25319 AEVTPSQHGNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.296 0 0 0 0 0 0 0 0 0 0 0 Q14147 DHX34_HUMAN Probable ATP-dependent RNA helicase DHX34 (EC 3.6.4.13) (DEAH box protein 34) (DExH-box helicase 34) DHX34 DDX34 KIAA0134 Homo sapiens (Human) "negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of phosphorylation [GO:0042327]" membrane [GO:0016020] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; helicase activity [GO:0004386]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.88813 -0.43306 APSEEEALEK 11.7551 11.6262 11.7645 0 0 0 0 0 11.5269 0 0 0 0 0 0 0 10.6744 0 0 0 0 0 0 0 0 0 0 Q14149 MORC3_HUMAN MORC family CW-type zinc finger protein 3 (Nuclear matrix protein 2) (Zinc finger CW-type coiled-coil domain protein 3) MORC3 KIAA0136 NXP2 ZCWCC3 Homo sapiens (Human) antiviral innate immune response [GO:0140374]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cellular senescence [GO:2000774]; post-embryonic development [GO:0009791]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821] chromatin [GO:0000785]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605] ATP hydrolysis activity [GO:0016887]; DNA binding [GO:0003677]; methylated histone binding [GO:0035064]; protein-macromolecule adaptor activity [GO:0030674]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270] 0.90956 -0.74437 LSALCPK 0 0 0 0 0 0 13.0093 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14151 SAFB2_HUMAN Scaffold attachment factor B2 (SAF-B2) SAFB2 KIAA0138 Homo sapiens (Human) regulation of androgen receptor signaling pathway [GO:0060765]; regulation of mRNA processing [GO:0050684]; regulation of transcription by RNA polymerase II [GO:0006357]; Sertoli cell differentiation [GO:0060008] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] identical protein binding [GO:0042802]; RNA binding [GO:0003723]; sequence-specific DNA binding [GO:0043565] 0.96 -1.8497 LEAFHER 0 0 0 0 0 8.86796 0 0 8.25626 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.7939 0 0 Q14152 EIF3A_HUMAN Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Eukaryotic translation initiation factor 3 subunit 10) (eIF-3-theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) EIF3A EIF3S10 KIAA0139 Homo sapiens (Human) formation of cytoplasmic translation initiation complex [GO:0001732]; IRES-dependent viral translational initiation [GO:0075522]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; translation reinitiation [GO:0002188]; translational initiation [GO:0006413]; viral translational termination-reinitiation [GO:0075525] "cytoplasm [GO:0005737]; cytosol [GO:0005829]; eukaryotic 43S preinitiation complex [GO:0016282]; eukaryotic 48S preinitiation complex [GO:0033290]; eukaryotic translation initiation factor 3 complex [GO:0005852]; eukaryotic translation initiation factor 3 complex, eIF3e [GO:0071540]; eukaryotic translation initiation factor 3 complex, eIF3m [GO:0071541]; membrane [GO:0016020]; microtubule [GO:0005874]; multi-eIF complex [GO:0043614]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; postsynaptic density [GO:0014069]" mRNA binding [GO:0003729]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; translation initiation factor activity [GO:0003743] 0.9691 -7.033 AIVDAAR 0 0 0 0 0 0 0 0 0 11.0325 0 0 9.67152 0 0 8.47249 10.629 0 0 0 0 0 0 0 0 0 9.60875 Q14153 FA53B_HUMAN Protein FAM53B (Protein simplet) FAM53B KIAA0140 SMP Homo sapiens (Human) positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein import into nucleus [GO:0006606]; regulation of canonical Wnt signaling pathway [GO:0060828]; Wnt signaling pathway [GO:0016055] nucleus [GO:0005634] 0.55979 0.54285 EAVTACAVTSLIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3693 0 8.71184 0 0 0 0 0 0 0 0 0 0 Q14154 DELE1_HUMAN "DAP3-binding cell death enhancer 1 (DAP3-binding cell death enhancer 1, long form) (DELE1(L)) (Death ligand signal enhancer) [Cleaved into: DAP3-binding cell death enhancer 1 short form (DELE1(S)) (S-DELE1)]" DELE1 DELE KIAA0141 Homo sapiens (Human) extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; HRI-mediated signaling [GO:0140468]; integrated stress response signaling [GO:0140467]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281] cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] protein kinase binding [GO:0019901]; protein serine/threonine kinase activator activity [GO:0043539] 0.96778 -2.9428 TLGPSLWR 0 10.2077 0 0 0 0 0 9.34804 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14155 ARHG7_HUMAN Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85) ARHGEF7 COOL1 KIAA0142 P85SPR PAK3BP PIXB Nbla10314 Homo sapiens (Human) ephrin receptor signaling pathway [GO:0048013]; focal adhesion assembly [GO:0048041]; Golgi organization [GO:0007030]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; negative regulation of microtubule nucleation [GO:1905833]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of GTPase activity [GO:0043547]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of GTP binding [GO:1904424]; signal transduction [GO:0007165] cell cortex [GO:0005938]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; mitotic spindle pole [GO:0097431]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]; ruffle [GO:0001726] gamma-tubulin binding [GO:0043015]; guanyl-nucleotide exchange factor activity [GO:0005085]; protein kinase binding [GO:0019901] 0.2188 0.88472 HMEDYHTDR 0 0 0 0 0 12.3808 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8125 0 0 0 0 Q14156 EFR3A_HUMAN Protein EFR3 homolog A (Protein EFR3-like) EFR3A KIAA0143 Homo sapiens (Human) phosphatidylinositol phosphate biosynthetic process [GO:0046854]; protein localization to plasma membrane [GO:0072659] cytosol [GO:0005829]; plasma membrane [GO:0005886] 0.79293 0.24578 IIPDVADLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.378 0 0 0 0 0 0 0 0 10.2079 0 Q14157 UBP2L_HUMAN Ubiquitin-associated protein 2-like (Protein NICE-4) (RNA polymerase II degradation factor UBAP2L) UBAP2L KIAA0144 NICE4 Homo sapiens (Human) binding of sperm to zona pellucida [GO:0007339]; hematopoietic stem cell homeostasis [GO:0061484]; positive regulation of stress granule assembly [GO:0062029]; stress granule assembly [GO:0034063] chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; nucleus [GO:0005634]; PcG protein complex [GO:0031519] RNA binding [GO:0003723] 0.63067 0.39886 SGGPSGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0532 0 0 0 0 0 0 10.3647 0 Q14159 SPIDR_HUMAN DNA repair-scaffolding protein (Scaffolding protein involved in DNA repair) SPIDR KIAA0146 Homo sapiens (Human) cellular response to camptothecin [GO:0072757]; cellular response to hydroxyurea [GO:0072711]; cellular response to ionizing radiation [GO:0071479]; DNA damage response [GO:0006974]; double-strand break repair via homologous recombination [GO:0000724]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of protein-containing complex assembly [GO:0031334]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of establishment of protein localization to chromosome [GO:0070202] nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654] 0.80338 0.2374 ERSAISLWRHQCISYQK 0 10.8424 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14160 SCRIB_HUMAN Protein scribble homolog (Scribble) (hScrib) (Protein LAP4) SCRIB CRIB1 KIAA0147 LAP4 SCRB1 VARTUL Homo sapiens (Human) "activation of GTPase activity [GO:0090630]; apoptotic process involved in morphogenesis [GO:0060561]; astrocyte cell migration [GO:0043615]; auditory receptor cell stereocilium organization [GO:0060088]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; cochlear nucleus development [GO:0021747]; establishment of apical/basal cell polarity [GO:0035089]; establishment of T cell polarity [GO:0001768]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; mammary gland duct morphogenesis [GO:0060603]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of mitotic cell cycle [GO:0045930]; neural tube closure [GO:0001843]; neurotransmitter receptor transport postsynaptic membrane to endosome [GO:0098968]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; polarized epithelial cell differentiation [GO:0030859]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; positive regulation of receptor recycling [GO:0001921]; positive regulation of type II interferon production [GO:0032729]; post-anal tail morphogenesis [GO:0036342]; protein localization to adherens junction [GO:0071896]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle targeting [GO:0016080]; wound healing [GO:0042060]" adherens junction [GO:0005912]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell-cell contact zone [GO:0044291]; cell-cell junction [GO:0005911]; extracellular exosome [GO:0070062]; extrinsic component of postsynaptic density membrane [GO:0099147]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; lamellipodium [GO:0030027]; myelin sheath abaxonal region [GO:0035748]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; Scrib-APC-beta-catenin complex [GO:0034750] cadherin binding [GO:0045296]; signaling adaptor activity [GO:0035591] 0.95283 -1.4724 AEEEEASTEEEDK 0 11.723 11.0464 12.9656 0 8.41147 8.83895 11.0934 9.07162 11.4243 9.26083 9.45962 0 9.70077 9.20105 0 0 0 0 0 0 0 0 0 9.78588 0 0 Q14161 GIT2_HUMAN ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2) GIT2 KIAA0148 Homo sapiens (Human) brain development [GO:0007420]; regulation of ARF protein signal transduction [GO:0032012]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; synaptic vesicle recycling [GO:0036465] focal adhesion [GO:0005925]; nucleoplasm [GO:0005654]; presynapse [GO:0098793]; synapse [GO:0045202] GTPase activator activity [GO:0005096]; metal ion binding [GO:0046872]; small GTPase binding [GO:0031267] 0.88491 -0.14653 TSLRLLTSSAYRLQSECK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.4816 0 0 0 0 0 0 0 0 0 0 0 Q14164 IKKE_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i) IKBKE IKKE IKKI KIAA0151 Homo sapiens (Human) cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; gene expression [GO:0010467]; immune response [GO:0006955]; interleukin-17-mediated signaling pathway [GO:0097400]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mRNA stabilization [GO:0048255]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of lipid storage [GO:0010884]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein phosphorylation [GO:0006468]; regulation of protein-containing complex assembly [GO:0043254]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to interferon-beta [GO:0035456]; type I interferon-mediated signaling pathway [GO:0060337] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial membrane [GO:0031966]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; serine/threonine protein kinase complex [GO:1902554] ATP binding [GO:0005524]; identical protein binding [GO:0042802]; IkappaB kinase activity [GO:0008384]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; NF-kappaB-inducing kinase activity [GO:0004704]; protein phosphatase binding [GO:0019903]; protein serine/threonine kinase activity [GO:0004674]; ubiquitin protein ligase binding [GO:0031625] 0.85785 0.1001 FVPKVDLQADYNTAK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0767 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14166 TTL12_HUMAN Tubulin--tyrosine ligase-like protein 12 (Inactive tubulin--tyrosine ligase-like protein 12) TTLL12 KIAA0153 Homo sapiens (Human) innate immune response [GO:0045087]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; protein modification process [GO:0036211]; regulation of mitotic cell cycle [GO:0007346] cytoplasm [GO:0005737]; cytosol [GO:0005829]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; spindle [GO:0005819] ATP binding [GO:0005524]; H4K20me3 modified histone binding [GO:1990889]; tubulin binding [GO:0015631] 0.97012 -3.2836 AGGPEGPPWLPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.43786 0 0 0 0 0 0 0 Q14168 MPP2_HUMAN MAGUK p55 subfamily member 2 (Discs large homolog 2) (Protein MPP2) MPP2 DLG2 Homo sapiens (Human) excitatory postsynaptic potential [GO:0060079]; long-term synaptic potentiation [GO:0060291]; protein homooligomerization [GO:0051260] cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dendrite membrane [GO:0032590]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] 0.47458 0.62649 EGQGYSFVSR 0 0 0 0 0 0 8.53294 0 0 9.8967 0 0 0 0 0 8.50016 8.34345 0 0 0 0 0 0 0 0 0 0 Q14181 DPOA2_HUMAN DNA polymerase alpha subunit B (DNA polymerase alpha 70 kDa subunit) POLA2 Homo sapiens (Human) "DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; DNA replication, synthesis of RNA primer [GO:0006269]; protein import into nucleus [GO:0006606]" alpha DNA polymerase:primase complex [GO:0005658]; cytosol [GO:0005829]; nucleoplasm [GO:0005654] DNA binding [GO:0003677] 0.80306 0.23849 EYSLFPGQVVIMEGINTTGR 15.6511 0 0 14.4031 0 14.4184 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14183 DOC2A_HUMAN Double C2-like domain-containing protein alpha (Doc2) (Doc2-alpha) DOC2A Homo sapiens (Human) calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; chemical synaptic transmission [GO:0007268]; exocytosis [GO:0006887]; nervous system development [GO:0007399]; regulation of calcium ion-dependent exocytosis [GO:0017158]; spontaneous neurotransmitter secretion [GO:0061669] cell junction [GO:0030054]; extrinsic component of synaptic vesicle membrane [GO:0098850]; glutamatergic synapse [GO:0098978]; lysosome [GO:0005764]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; synapse [GO:0045202] calcium-dependent phospholipid binding [GO:0005544]; metal ion binding [GO:0046872] 0.96395 -2.2052 KHFNICLER 0 0 0 0 0 0 0 0 0 0 9.94639 0 0 0 0 0 0 0 0 0 0 0 0 0 11.8042 0 0 Q14184 DOC2B_HUMAN Double C2-like domain-containing protein beta (Doc2-beta) DOC2B DOC2BL Homo sapiens (Human) calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; exocytosis [GO:0006887]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of insulin secretion [GO:0032024]; positive regulation of vesicle fusion [GO:0031340]; protein localization [GO:0008104]; regulation of calcium ion-dependent exocytosis [GO:0017158]; spontaneous neurotransmitter secretion [GO:0061669] cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; synapse [GO:0045202] calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; syntaxin binding [GO:0019905] 0.84026 0.14395 TLNPEFNEEFCYEIK 9.43438 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14185 DOCK1_HUMAN Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180) DOCK1 Homo sapiens (Human) "apoptotic process [GO:0006915]; cell migration [GO:0016477]; integrin-mediated signaling pathway [GO:0007229]; myoblast fusion [GO:0007520]; phagocytosis, engulfment [GO:0006911]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; guanyl-nucleotide exchange factor complex [GO:0032045]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; SH3 domain binding [GO:0017124]; small GTPase binding [GO:0031267] 0.93572 -1.2914 DMWYNLGQHKIK 0 0 0 0 0 0 0 0 0 9.69213 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14188 TFDP2_HUMAN Transcription factor Dp-2 (E2F dimerization partner 2) TFDP2 DP2 Homo sapiens (Human) cell cycle [GO:0007049]; heart development [GO:0007507]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; mitotic spindle [GO:0072686]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575] "DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein domain specific binding [GO:0019904]; transcription factor binding [GO:0008134]" 0.80069 0.23929 TVIDCSISSDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.4177 0 0 0 0 0 0 0 0 Q14190 SIM2_HUMAN Single-minded homolog 2 (Class E basic helix-loop-helix protein 15) (bHLHe15) SIM2 BHLHE15 Homo sapiens (Human) cell differentiation [GO:0030154]; embryonic pattern specification [GO:0009880]; lung development [GO:0030324]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654] "DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.91374 -0.76028 GQVTTKYYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1267 0 0 0 0 0 0 0 0 0 Q14191 WRN_HUMAN "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (DNA helicase, RecQ-like type 3) (RecQ protein-like 2) (Werner syndrome protein) [Includes: 3'-5' exonuclease (EC 3.1.-.-); ATP-dependent helicase (EC 3.6.4.12)]" WRN RECQ3 RECQL2 Homo sapiens (Human) aging [GO:0007568]; base-excision repair [GO:0006284]; brain development [GO:0007420]; cellular response to gamma radiation [GO:0071480]; cellular response to starvation [GO:0009267]; cellular senescence [GO:0090398]; determination of adult lifespan [GO:0008340]; DNA damage response [GO:0006974]; DNA duplex unwinding [GO:0032508]; DNA metabolic process [GO:0006259]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; G-quadruplex DNA unwinding [GO:0044806]; multicellular organism aging [GO:0010259]; positive regulation of hydrolase activity [GO:0051345]; positive regulation of strand invasion [GO:0098530]; protein localization to nucleolus [GO:1902570]; regulation of growth rate [GO:0040009]; replication fork processing [GO:0031297]; replicative senescence [GO:0090399]; response to oxidative stress [GO:0006979]; response to UV-C [GO:0010225]; t-circle formation [GO:0090656]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomeric D-loop disassembly [GO:0061820] "centrosome [GO:0005813]; chromosome [GO:0005694]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; replication fork [GO:0005657]" 3'-5' DNA helicase activity [GO:0043138]; 3'-5' exonuclease activity [GO:0008408]; 3'-flap-structured DNA binding [GO:0070337]; 8-hydroxy-2'-deoxyguanosine DNA binding [GO:1905773]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; bubble DNA binding [GO:0000405]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; exonuclease activity [GO:0004527]; forked DNA-dependent helicase activity [GO:0061749]; four-way junction DNA binding [GO:0000400]; four-way junction helicase activity [GO:0009378]; G-quadruplex DNA binding [GO:0051880]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; MutLalpha complex binding [GO:0032405]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; telomeric D-loop binding [GO:0061821]; telomeric G-quadruplex DNA binding [GO:0061849]; Y-form DNA binding [GO:0000403] 0.95779 -1.6648 HLPHAFSKLENPR 0 0 0 0 0 0 9.86737 0 0 11.0851 0 0 0 10.1784 0 0 0 0 9.03507 0 0 0 10.1903 0 0 0 0 Q14192 FHL2_HUMAN Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3) FHL2 DRAL SLIM3 Homo sapiens (Human) atrial cardiac muscle cell development [GO:0055014]; heart trabecula formation [GO:0060347]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; response to hormone [GO:0009725]; ventricular cardiac muscle cell development [GO:0055015] focal adhesion [GO:0005925]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Z disc [GO:0030018] bHLH transcription factor binding [GO:0043425]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transcription coregulator activity [GO:0003712]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134] 0.89845 -0.6481 QHAMQCVQCK 0 0 0 0 0 0 0 10.2204 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14195 DPYL3_HUMAN Dihydropyrimidinase-related protein 3 (DRP-3) (Collapsin response mediator protein 4) (CRMP-4) (Unc-33-like phosphoprotein 1) (ULIP-1) DPYSL3 CRMP4 DRP3 ULIP ULIP1 Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin filament bundle assembly [GO:0051017]; cellular response to cytokine stimulus [GO:0071345]; negative regulation of cell migration [GO:0030336]; negative regulation of neuron projection development [GO:0010977]; neuron development [GO:0048666]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of neuron projection development [GO:0010976]; response to axon injury [GO:0048678] cell body [GO:0044297]; cytosol [GO:0005829]; exocytic vesicle [GO:0070382]; extracellular space [GO:0005615]; filamentous actin [GO:0031941]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; synapse [GO:0045202] "chondroitin sulfate binding [GO:0035374]; filamin binding [GO:0031005]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [GO:0016812]; identical protein binding [GO:0042802]; SH3 domain binding [GO:0017124]" 0.91565 -0.76343 KNIPRITSDR 0 0 0 0 0 0 0 0 9.62523 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14202 ZMYM3_HUMAN Zinc finger MYM-type protein 3 (Zinc finger protein 261) ZMYM3 DXS6673E KIAA0385 ZNF261 Homo sapiens (Human) cytoskeleton organization [GO:0007010]; regulation of cell morphogenesis [GO:0022604] nucleoplasm [GO:0005654] DNA binding [GO:0003677]; zinc ion binding [GO:0008270] 0.96551 -2.2984 KGRDTGPGK 9.85641 9.40018 0 0 0 0 0 8.30684 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14204 DYHC1_HUMAN "Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic)" DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325 Homo sapiens (Human) cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; establishment of spindle localization [GO:0051293]; mitotic spindle organization [GO:0007052]; nuclear migration [GO:0007097]; P-body assembly [GO:0033962]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of intracellular transport [GO:0032388]; positive regulation of spindle assembly [GO:1905832]; regulation of metaphase plate congression [GO:0090235]; regulation of mitotic spindle organization [GO:0060236]; retrograde axonal transport [GO:0008090]; stress granule assembly [GO:0034063] axon cytoplasm [GO:1904115]; azurophil granule lumen [GO:0035578]; cell cortex [GO:0005938]; centrosome [GO:0005813]; cytoplasmic dynein complex [GO:0005868]; cytoplasmic microtubule [GO:0005881]; cytosol [GO:0005829]; dynein complex [GO:0030286]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; filopodium [GO:0030175]; membrane [GO:0016020]; microtubule [GO:0005874] ATP binding [GO:0005524]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; minus-end-directed microtubule motor activity [GO:0008569]; RNA binding [GO:0003723] 0.96899 -4.8427 AATSPALFNR 0 0 0 0 0 0 8.75024 8.41511 8.53446 11.2054 16.1138 11.5 10.3446 0 0 0 10.4211 0 11.2763 9.54112 11.6834 10.4018 11.7676 9.41754 12.1751 11.524 13.4564 Q14207 NPAT_HUMAN Protein NPAT (Nuclear protein of the ataxia telangiectasia mutated locus) (Nuclear protein of the ATM locus) (p220) NPAT CAND3 E14 Homo sapiens (Human) in utero embryonic development [GO:0001701]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083] Cajal body [GO:0015030]; cytoplasm [GO:0005737]; Gemini of coiled bodies [GO:0097504]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription corepressor activity [GO:0003714] 0.96131 -2.594 DNTQQFRASSRSTTK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.94755 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14209 E2F2_HUMAN Transcription factor E2F2 (E2F-2) E2F2 Homo sapiens (Human) intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; lens fiber cell apoptotic process [GO:1990086]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of sprouting angiogenesis [GO:1903671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; transcription initiation at RNA polymerase II promoter [GO:0006367] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; Rb-E2F complex [GO:0035189]; RNA polymerase II transcription regulator complex [GO:0090575] "cis-regulatory region sequence-specific DNA binding [GO:0000987]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein dimerization activity [GO:0046983]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.56192 0.51597 LDLEGIGRPVVPEFPTPK 0 0 9.09268 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14232 EI2BA_HUMAN Translation initiation factor eIF-2B subunit alpha (eIF-2B GDP-GTP exchange factor subunit alpha) EIF2B1 EIF2BA Homo sapiens (Human) oligodendrocyte development [GO:0014003]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to peptide hormone [GO:0043434]; T cell receptor signaling pathway [GO:0050852]; translational initiation [GO:0006413] cytoplasm [GO:0005737]; cytosol [GO:0005829]; eukaryotic translation initiation factor 2B complex [GO:0005851]; membrane [GO:0016020]; plasma membrane [GO:0005886] identical protein binding [GO:0042802]; translation initiation factor activity [GO:0003743] 0.9545 -1.505 ISLSRNK 0 0 0 0 0 0 0 0 0 9.79606 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14236 EPAG_HUMAN Early lymphoid activation gene protein (DIAPH2 antisense RNA 1) (DIAPH2 antisense gene protein 1) DIAPH2-AS1 EPAG Homo sapiens (Human) signal transduction [GO:0007165] 0.9527 -1.4706 FLRMFYHQK 0 0 0 0 0 0 0 0 0 0 0 12.7099 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14240 IF4A2_HUMAN Eukaryotic initiation factor 4A-II (eIF-4A-II) (eIF4A-II) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-2) EIF4A2 DDX2B EIF4F Homo sapiens (Human) cellular response to leukemia inhibitory factor [GO:1990830]; cytoplasmic translational initiation [GO:0002183]; negative regulation of RNA-dependent RNA polymerase activity [GO:1900260]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413] cytosol [GO:0005829]; eukaryotic translation initiation factor 4F complex [GO:0016281]; perinuclear region of cytoplasm [GO:0048471] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; helicase activity [GO:0004386]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; translation initiation factor activity [GO:0003743] 0.84865 0.15726 ELAQQIQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.91244 0 Q14241 ELOA1_HUMAN Elongin-A (EloA) (Elongin 110 kDa subunit) (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Transcription elongation factor B polypeptide 3) ELOA TCEB3 MSTP059 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357]; transcription elongation by RNA polymerase II [GO:0006368]; transcription initiation at RNA polymerase II promoter [GO:0006367] elongin complex [GO:0070449]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; site of DNA damage [GO:0090734] 0.8982 -0.58183 DLVAQWK 10.0871 0 9.78658 0 0 9.87386 0 0 11.0341 10.7295 10.7791 10.6996 11.3553 11.4921 11.2261 0 8.98579 0 0 0 0 0 0 9.26552 0 0 0 Q14244 MAP7_HUMAN Ensconsin (Epithelial microtubule-associated protein of 115 kDa) (E-MAP-115) (Microtubule-associated protein 7) (MAP-7) MAP7 Homo sapiens (Human) establishment or maintenance of cell polarity [GO:0007163]; microtubule cytoskeleton organization [GO:0000226]; protein localization to plasma membrane [GO:0072659]; response to osmotic stress [GO:0006970] axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; microtubule cytoskeleton [GO:0015630]; perinuclear region of cytoplasm [GO:0048471] signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198] 0.96963 -4.96 AELGAGGDGHRGGDGAVR 0 0 0 0 0 0 0 0 0 0 0 0 8.63292 0 0 0 0 0 10.1933 0 9.77855 9.29999 10.0386 0 0 10.3517 9.60875 Q14246 AGRE1_HUMAN Adhesion G protein-coupled receptor E1 (EGF-like module receptor 1) (EGF-like module-containing mucin-like hormone receptor-like 1) (EMR1 hormone receptor) ADGRE1 EMR1 TM7LN3 Homo sapiens (Human) adaptive immune response [GO:0002250]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] external side of plasma membrane [GO:0009897]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; G protein-coupled receptor activity [GO:0004930] 0.96941 -3.3896 EEYKRWITGK 9.92656 9.74322 0 0 0 0 0 0 0 0 9.21388 9.51258 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14247 SRC8_HUMAN Src substrate cortactin (Amplaxin) (Oncogene EMS1) CTTN EMS1 Homo sapiens (Human) "actin cytoskeleton reorganization [GO:0031532]; cell motility [GO:0048870]; dendritic spine maintenance [GO:0097062]; extrinsic apoptotic signaling pathway [GO:0097191]; focal adhesion assembly [GO:0048041]; intracellular protein transport [GO:0006886]; lamellipodium organization [GO:0097581]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; neuron projection morphogenesis [GO:0048812]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of smooth muscle contraction [GO:0045987]; receptor-mediated endocytosis [GO:0006898]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of axon extension [GO:0030516]; signal transduction [GO:0007165]; substrate-dependent cell migration, cell extension [GO:0006930]" cell cortex [GO:0005938]; clathrin-coated pit [GO:0005905]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; mitotic spindle midzone [GO:1990023]; plasma membrane [GO:0005886]; podosome [GO:0002102]; ruffle [GO:0001726]; voltage-gated potassium channel complex [GO:0008076] cadherin binding [GO:0045296]; profilin binding [GO:0005522] 0.9663 -2.3545 ANFENLAK 0 9.73256 0 11.3265 11.9288 0 0 0 0 10.6963 0 0 8.87747 11.4428 11.6868 9.84403 0 9.87685 0 0 0 0 0 0 0 0 0 Q14258 TRI25_HUMAN E3 ubiquitin/ISG15 ligase TRIM25 (EC 6.3.2.n3) (Estrogen-responsive finger protein) (RING finger protein 147) (RING-type E3 ubiquitin transferase) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM25) (Tripartite motif-containing protein 25) (Ubiquitin/ISG15-conjugating enzyme TRIM25) (Zinc finger protein 147) TRIM25 EFP RNF147 ZNF147 Homo sapiens (Human) antiviral innate immune response [GO:0140374]; cellular response to leukemia inhibitory factor [GO:1990830]; cytosolic pattern recognition receptor signaling pathway [GO:0002753]; innate immune response [GO:0045087]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein K48-linked ubiquitination [GO:0070936]; protein monoubiquitination [GO:0006513]; regulation of protein localization [GO:0032880]; regulation of viral entry into host cell [GO:0046596]; response to estrogen [GO:0043627]; response to oxidative stress [GO:0006979]; response to vitamin D [GO:0033280]; suppression of viral release by host [GO:0044790]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral release from host cell [GO:0019076] cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654] cadherin binding [GO:0045296]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]; molecular function inhibitor activity [GO:0140678]; RIG-I binding [GO:0039552]; RNA binding [GO:0003723]; transcription coactivator activity [GO:0003713]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.95963 -1.7471 ISAWHNNVEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0905 0 0 0 0 9.87334 0 0 0 0 0 0 0 Q14289 FAK2_HUMAN Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK) PTK2B FAK2 PYK2 RAFTK Homo sapiens (Human) "activation of GTPase activity [GO:0090630]; activation of Janus kinase activity [GO:0042976]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; blood vessel endothelial cell migration [GO:0043534]; bone resorption [GO:0045453]; cell surface receptor signaling pathway [GO:0007166]; cellular defense response [GO:0006968]; cellular response to fluid shear stress [GO:0071498]; cellular response to retinoic acid [GO:0071300]; chemokine-mediated signaling pathway [GO:0070098]; endothelin receptor signaling pathway [GO:0086100]; epidermal growth factor receptor signaling pathway [GO:0007173]; focal adhesion assembly [GO:0048041]; glial cell proliferation [GO:0014009]; integrin-mediated signaling pathway [GO:0007229]; ionotropic glutamate receptor signaling pathway [GO:0035235]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; MAPK cascade [GO:0000165]; marginal zone B cell differentiation [GO:0002315]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone mineralization [GO:0030502]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of potassium ion transport [GO:0043267]; neuron projection development [GO:0031175]; oocyte maturation [GO:0001556]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell chemotaxis [GO:2000538]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron projection development [GO:0010976]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of translation [GO:0045727]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein-containing complex assembly [GO:0065003]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell adhesion [GO:0030155]; regulation of cell shape [GO:0008360]; regulation of cGMP-mediated signaling [GO:0010752]; regulation of establishment of cell polarity [GO:2000114]; regulation of inositol trisphosphate biosynthetic process [GO:0032960]; regulation of macrophage chemotaxis [GO:0010758]; regulation of NMDA receptor activity [GO:2000310]; regulation of postsynaptic density assembly [GO:0099151]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of synaptic plasticity [GO:0048167]; regulation of ubiquitin-dependent protein catabolic process [GO:2000058]; response to calcium ion [GO:0051592]; response to cAMP [GO:0051591]; response to cation stress [GO:0043157]; response to cocaine [GO:0042220]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to immobilization stress [GO:0035902]; response to ischemia [GO:0002931]; response to lithium ion [GO:0010226]; response to mechanical stimulus [GO:0009612]; response to xenobiotic stimulus [GO:0009410]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; stress fiber assembly [GO:0043149]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]" "apical dendrite [GO:0097440]; cell body [GO:0044297]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; NMDA selective glutamate receptor complex [GO:0017146]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; presynapse [GO:0098793]; Schaffer collateral - CA1 synapse [GO:0098685]" 3-phosphoinositide-dependent protein kinase binding [GO:0043423]; ATP binding [GO:0005524]; calmodulin-dependent protein kinase activity [GO:0004683]; NMDA glutamate receptor activity [GO:0004972]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein self-association [GO:0043621]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; ubiquitin protein ligase binding [GO:0031625] 0.75971 0.29421 FMSEAVIMK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.09827 0 9.74992 9.17794 0 9.41846 0 9.29857 0 0 0 0 0 0 Q14296 FASTK_HUMAN Fas-activated serine/threonine kinase (FAST kinase) (EC 2.7.11.1) (EC 2.7.11.8) FASTK Homo sapiens (Human) apoptotic signaling pathway [GO:0097190]; mitochondrial RNA processing [GO:0000963]; protein phosphorylation [GO:0006468]; regulation of mitochondrial mRNA stability [GO:0044528]; regulation of RNA splicing [GO:0043484] mitochondrial matrix [GO:0005759]; ribonucleoprotein granule [GO:0035770] ATP binding [GO:0005524]; Fas-activated serine/threonine kinase activity [GO:0033867]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; RNA binding [GO:0003723] 0.95948 -1.8844 ARCKYSHK 8.18646 0 0 0 0 0 0 8.44584 0 10.5283 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14314 FGL2_HUMAN Fibroleukin (Fibrinogen-like protein 2) (pT49) FGL2 Homo sapiens (Human) negative regulation of defense response to virus [GO:0050687]; negative regulation of dendritic cell antigen processing and presentation [GO:0002605]; negative regulation of macrophage antigen processing and presentation [GO:0002617]; negative regulation of memory T cell differentiation [GO:0043381]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291] collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; ficolin-1-rich granule lumen [GO:1904813] 0.96997 -3.3004 EAKMMIRPKHFKP 0 0 0 0 0 0 0 0 0 0 16.9261 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14315 FLNC_HUMAN Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin) FLNC ABPL FLN2 Homo sapiens (Human) sarcomere organization [GO:0045214] costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; intercellular bridge [GO:0045171]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018] actin filament binding [GO:0051015]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802] 0.61119 0.42001 GVAGVPAEFSIWTR 0 0 8.90355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14318 FKBP8_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (38 kDa FK506-binding protein) (38 kDa FKBP) (FKBP-38) (hFKBP38) (FK506-binding protein 8) (FKBP-8) (FKBPR38) (Rotamase) FKBP8 FKBP38 Homo sapiens (Human) apoptotic process [GO:0006915]; BMP signaling pathway [GO:0030509]; camera-type eye development [GO:0043010]; dorsal/ventral neural tube patterning [GO:0021904]; intracellular signal transduction [GO:0035556]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein phosphorylation [GO:0001933]; neuron fate specification [GO:0048665]; positive regulation of BMP signaling pathway [GO:0030513]; protein folding [GO:0006457]; protein localization to mitochondrion [GO:0070585]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of gene expression [GO:0010468]; smoothened signaling pathway [GO:0007224] cytosol [GO:0005829]; endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; mitochondrial envelope [GO:0005740]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991] calmodulin binding [GO:0005516]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding chaperone [GO:0044183] 0.92339 -1.0708 GAWSIPWK 0 0 0 0 0 0 0 0 0 9.0673 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14320 FA50A_HUMAN Protein FAM50A (Protein HXC-26) (Protein XAP-5) FAM50A DXS9928E HXC26 XAP5 Homo sapiens (Human) chromatin organization [GO:0006325]; mRNA processing [GO:0006397]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]; spermatogenesis [GO:0007283] nucleoplasm [GO:0005654]; nucleus [GO:0005634] RNA binding [GO:0003723] 0.92155 -0.93322 DESHAGK 0 0 0 0 0 7.81372 0 9.52244 0 0 0 0 10.6609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14324 MYPC2_HUMAN "Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform)" MYBPC2 MYBPCF Homo sapiens (Human) cell adhesion [GO:0007155] cytosol [GO:0005829]; myosin filament [GO:0032982] actin binding [GO:0003779]; structural constituent of muscle [GO:0008307] 0.95975 -1.8593 EIAEPPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2033 Q14331 FRG1_HUMAN Protein FRG1 (FSHD region gene 1 protein) FRG1 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; muscle organ development [GO:0007517]; rRNA processing [GO:0006364]" Cajal body [GO:0015030]; catalytic step 2 spliceosome [GO:0071013]; nucleolus [GO:0005730]; striated muscle dense body [GO:0055120]; Z disc [GO:0030018] actin filament binding [GO:0051015]; RNA binding [GO:0003723] 0.94026 -1.311 GNVKQCEINYVKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.65882 0 0 0 0 0 Q14344 GNA13_HUMAN Guanine nucleotide-binding protein subunit alpha-13 (G alpha-13) (G-protein subunit alpha-13) GNA13 Homo sapiens (Human) activation of phospholipase D activity [GO:0031584]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; branching involved in blood vessel morphogenesis [GO:0001569]; cell differentiation [GO:0030154]; in utero embryonic development [GO:0001701]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; platelet activation [GO:0030168]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; regulation of blood pressure [GO:0008217]; regulation of cell shape [GO:0008360]; regulation of fibroblast migration [GO:0010762]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165] brush border membrane [GO:0031526]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; heterotrimeric G-protein complex [GO:0005834]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886] D5 dopamine receptor binding [GO:0031752]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; guanyl-nucleotide exchange factor activity [GO:0005085]; metal ion binding [GO:0046872] 0.95016 -1.3838 YFLDNLDK 0 0 0 0 0 0 0 0 0 0 0 9.63615 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14353 GAMT_HUMAN Guanidinoacetate N-methyltransferase (EC 2.1.1.2) GAMT Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; creatine biosynthetic process [GO:0006601]; creatine metabolic process [GO:0006600]; methylation [GO:0032259]; muscle contraction [GO:0006936]; regulation of multicellular organism growth [GO:0040014]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] guanidinoacetate N-methyltransferase activity [GO:0030731]; methyltransferase activity [GO:0008168] 0.69712 0.37555 VQEAPIDEHWIIECNDGVFQR 0 0 0 0 0 0 0 0 0 0 0 0 0 11.6023 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14392 LRC32_HUMAN Transforming growth factor beta activator LRRC32 (Garpin) (Glycoprotein A repetitions predominant) (GARP) (Leucine-rich repeat-containing protein 32) LRRC32 D11S833E Homo sapiens (Human) negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of cytokine production [GO:0001818]; positive regulation of gene expression [GO:0010628]; regulation of transforming growth factor beta activation [GO:1901388]; regulation of transforming growth factor beta3 activation [GO:1901398]; secondary palate development [GO:0062009]; transforming growth factor beta receptor signaling pathway [GO:0007179] cell surface [GO:0009986]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] transforming growth factor beta binding [GO:0050431] 0.96855 -2.7689 LTRHTFR 0 0 10.3121 0 0 0 0 0 0 11.8355 0 11.3235 9.62288 0 8.56255 10.5199 0 0 0 0 0 0 0 0 0 0 0 Q14393 GAS6_HUMAN Growth arrest-specific protein 6 (GAS-6) (AXL receptor tyrosine kinase ligand) GAS6 AXLLG Homo sapiens (Human) activation of protein kinase B activity [GO:0032148]; animal organ regeneration [GO:0031100]; apoptotic cell clearance [GO:0043277]; B cell chemotaxis [GO:0035754]; blood coagulation [GO:0007596]; calcium ion transmembrane transport [GO:0070588]; cell-substrate adhesion [GO:0031589]; cellular response to glucose stimulus [GO:0071333]; cellular response to growth factor stimulus [GO:0071363]; cellular response to interferon-alpha [GO:0035457]; cellular response to starvation [GO:0009267]; cellular response to vitamin K [GO:0071307]; cellular response to xenobiotic stimulus [GO:0071466]; dendritic cell differentiation [GO:0097028]; enzyme-linked receptor protein signaling pathway [GO:0007167]; extracellular matrix assembly [GO:0085029]; fibroblast apoptotic process [GO:0044346]; fusion of virus membrane with host plasma membrane [GO:0019064]; hematopoietic stem cell migration to bone marrow [GO:0097241]; myeloid cell apoptotic process [GO:0033028]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of dendritic cell apoptotic process [GO:2000669]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of fibroblast apoptotic process [GO:2000270]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of myeloid cell apoptotic process [GO:0033033]; negative regulation of oligodendrocyte apoptotic process [GO:1900142]; negative regulation of renal albumin absorption [GO:2000533]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of type II interferon production [GO:0032689]; neuron migration [GO:0001764]; peptidyl-serine phosphorylation [GO:0018105]; phagocytosis [GO:0006909]; positive regulation of cytokine-mediated signaling pathway [GO:0001961]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of glomerular filtration [GO:0003104]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of TOR signaling [GO:0032008]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; receptor-mediated virion attachment to host cell [GO:0046813]; signal transduction [GO:0007165]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079] cytoplasm [GO:0005737]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; platelet alpha granule lumen [GO:0031093] calcium ion binding [GO:0005509]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; phosphatidylserine binding [GO:0001786]; protein tyrosine kinase activator activity [GO:0030296]; protein-macromolecule adaptor activity [GO:0030674]; receptor ligand activity [GO:0048018]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102] 0.72803 0.33944 AFQVFEEAK 0 0 0 8.27044 10.8552 0 0 0 8.46626 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14416 GRM2_HUMAN Metabotropic glutamate receptor 2 (mGluR2) GRM2 GPRC1B MGLUR2 Homo sapiens (Human) "behavioral response to nicotine [GO:0035095]; chemical synaptic transmission [GO:0007268]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gene expression [GO:0010467]; glutamate secretion [GO:0014047]; intracellular glutamate homeostasis [GO:0090461]; long-term synaptic depression [GO:0060292]; negative regulation of adenylate cyclase activity [GO:0007194]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of dopamine secretion [GO:0014059]; regulation of glutamate secretion [GO:0014048]; regulation of protein kinase B signaling [GO:0051896]; regulation of response to drug [GO:2001023]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to cocaine [GO:0042220]" astrocyte projection [GO:0097449]; axon [GO:0030424]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734] calcium channel regulator activity [GO:0005246]; G protein-coupled receptor activity [GO:0004930]; glutamate receptor activity [GO:0008066]; group II metabotropic glutamate receptor activity [GO:0001641]; scaffold protein binding [GO:0097110] 0.90521 -0.72082 APTSRFGSAAAR 9.82866 0 0 0 0 0 0 0 0 10.0988 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3939 0 Q14432 PDE3A_HUMAN "cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A) (cGMP-inhibited cAMP phosphodiesterase) (cGI-PDE)" PDE3A Homo sapiens (Human) apoptotic signaling pathway [GO:0097190]; cAMP-mediated signaling [GO:0019933]; cellular response to cGMP [GO:0071321]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP-mediated signaling [GO:0019934]; G protein-coupled receptor signaling pathway [GO:0007186]; lipid metabolic process [GO:0006629]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of vascular permeability [GO:0043116]; oocyte maturation [GO:0001556]; positive regulation of oocyte development [GO:0060282]; positive regulation of vascular permeability [GO:0043117]; regulation of meiotic nuclear division [GO:0040020]; regulation of ribonuclease activity [GO:0060700]; response to xenobiotic stimulus [GO:0009410] cytosol [GO:0005829]; membrane [GO:0016020] "3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP-inhibited cyclic-nucleotide phosphodiesterase activity [GO:0004119]; estrogen binding [GO:0099130]; metal ion binding [GO:0046872]; nuclear estrogen receptor activity [GO:0030284]" 0.88257 -0.11669 SHRRTSLPCIPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3156 0 0 0 Q14435 GALT3_HUMAN Polypeptide N-acetylgalactosaminyltransferase 3 (EC 2.4.1.41) (Polypeptide GalNAc transferase 3) (GalNAc-T3) (pp-GaNTase 3) (Protein-UDP acetylgalactosaminyltransferase 3) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3) GALNT3 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; fibroblast growth factor receptor signaling pathway [GO:0008543]; O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via serine [GO:0018242]; protein O-linked glycosylation via threonine [GO:0018243]; spermatogenesis [GO:0007283] extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471] calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; manganese ion binding [GO:0030145]; polypeptide N-acetylgalactosaminyltransferase activity [GO:0004653] 0.9051 -0.73109 EIFYRRNTDAAK 0 0 0 8.99687 0 9.36728 0 0 9.87583 0 0 0 0 0 0 0 0 8.92083 0 0 0 0 0 0 0 0 0 Q14444 CAPR1_HUMAN Caprin-1 (Cell cycle-associated protein 1) (Cytoplasmic activation- and proliferation-associated protein 1) (GPI-anchored membrane protein 1) (GPI-anchored protein p137) (GPI-p137) (p137GPI) (Membrane component chromosome 11 surface marker 1) (RNA granule protein 105) CAPRIN1 GPIAP1 GPIP137 M11S1 RNG105 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of translation [GO:0017148]; non-membrane-bounded organelle assembly [GO:0140694]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of stress granule assembly [GO:0062029]; regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0106288] cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; intracellular non-membrane-bounded organelle [GO:0043232]; lamellipodium [GO:0030027]; membrane [GO:0016020]; P-body [GO:0000932]; postsynapse [GO:0098794] ATP binding [GO:0005524]; molecular condensate scaffold activity [GO:0140693]; molecular function activator activity [GO:0140677]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; signaling adaptor activity [GO:0035591]; translation regulator activity [GO:0045182] 0.89922 -0.68496 EQLMREEAEQK 0 0 0 0 0 0 0 0 11.6192 9.08428 0 0 0 0 0 0 9.70266 0 0 0 0 0 0 0 0 0 0 Q14457 BECN1_HUMAN Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197) [Cleaved into: Beclin-1-C 35 kDa; Beclin-1-C 37 kDa] BECN1 GT197 Homo sapiens (Human) aging [GO:0007568]; amyloid-beta metabolic process [GO:0050435]; apoptotic process [GO:0006915]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cell division [GO:0051301]; cellular defense response [GO:0006968]; cellular response to aluminum ion [GO:0071275]; cellular response to amino acid starvation [GO:0034198]; cellular response to copper ion [GO:0071280]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucose starvation [GO:0042149]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitrogen starvation [GO:0006995]; defense response to virus [GO:0051607]; early endosome to late endosome transport [GO:0045022]; engulfment of apoptotic cell [GO:0043652]; late endosome to vacuole transport [GO:0045324]; lysosome organization [GO:0007040]; macroautophagy [GO:0016236]; mitophagy [GO:0000423]; mitotic metaphase plate congression [GO:0007080]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagosome assembly [GO:1902902]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of lysosome organization [GO:1905672]; negative regulation of programmed cell death [GO:0043069]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; neuron development [GO:0048666]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of attachment of mitotic spindle microtubules to kinetochore [GO:1902425]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of autophagy [GO:0010508]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein-containing complex assembly [GO:0065003]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of catalytic activity [GO:0050790]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241]; response to hypoxia [GO:0001666]; response to iron(II) ion [GO:0010040]; response to lead ion [GO:0010288]; response to mitochondrial depolarisation [GO:0098780]; response to vitamin E [GO:0033197]; response to xenobiotic stimulus [GO:0009410]; selective autophagy [GO:0061912]; suppression by virus of host autophagy [GO:0039521] "autophagosome [GO:0005776]; cytoplasm [GO:0005737]; cytoplasmic side of mitochondrial outer membrane [GO:0032473]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; nuclear body [GO:0016604]; phagocytic vesicle [GO:0045335]; phagophore assembly site [GO:0000407]; phosphatidylinositol 3-kinase complex, class III [GO:0035032]; phosphatidylinositol 3-kinase complex, class III, type I [GO:0034271]; phosphatidylinositol 3-kinase complex, class III, type II [GO:0034272]; trans-Golgi network [GO:0005802]" GTPase binding [GO:0051020]; identical protein binding [GO:0042802]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein kinase binding [GO:0019901]; protein-macromolecule adaptor activity [GO:0030674]; ubiquitin protein ligase binding [GO:0031625] 0.92635 -1.2081 ELALEEER 9.31309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.82941 0 0 0 0 Q14498 RBM39_HUMAN RNA-binding protein 39 (CAPER alpha) (CAPERalpha) (Hepatocellular carcinoma protein 1) (RNA-binding motif protein 39) (RNA-binding region-containing protein 2) (Splicing factor HCC1) RBM39 HCC1 RNPC2 Homo sapiens (Human) "mRNA processing [GO:0006397]; regulation of mRNA splicing, via spliceosome [GO:0048024]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]" centriolar satellite [GO:0034451]; microtubule cytoskeleton [GO:0015630]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991] RNA binding [GO:0003723]; RS domain binding [GO:0050733]; U1 snRNP binding [GO:1990446] 0.96795 -3.6633 GRYRSPYSGPK 0 9.62505 0 0 0 0 0 0 10.1123 0 0 0 0 0 0 0 0 0 0 0 0 0 8.68011 0 0 0 0 Q14500 KCJ12_HUMAN "ATP-sensitive inward rectifier potassium channel 12 (Inward rectifier K(+) channel Kir2.2) (IRK-2) (Inward rectifier K(+) channel Kir2.2v) (Potassium channel, inwardly rectifying subfamily J member 12)" KCNJ12 IRK2 KCNJN1 Homo sapiens (Human) muscle contraction [GO:0006936]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transport [GO:0006813]; protein homotetramerization [GO:0051289]; regulation of heart contraction [GO:0008016]; regulation of monoatomic ion transmembrane transport [GO:0034765] membrane [GO:0016020]; plasma membrane [GO:0005886] inward rectifier potassium channel activity [GO:0005242] 0.8777 -0.0028308 TYEVPSTPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.3799 0 0 0 Q14507 EP3A_HUMAN Epididymal secretory protein E3-alpha (Human epididymis-specific protein 3-alpha) (HE3-alpha) EDDM3A FAM12A HE3A Homo sapiens (Human) sperm displacement [GO:0007321] extracellular space [GO:0005615] 0.55041 0.56403 GKSFHMFIYSLWFK 0 0 9.25295 0 0 0 0 8.8352 0 0 0 11.9148 0 8.73617 8.61842 0 0 0 0 0 0 0 0 0 0 0 0 Q14511 CASL_HUMAN Enhancer of filamentation 1 (hEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (Cas scaffolding protein family member 2) (CASS2) (Neural precursor cell expressed developmentally down-regulated protein 9) (NEDD-9) (Renal carcinoma antigen NY-REN-12) (p105) [Cleaved into: Enhancer of filamentation 1 p55] NEDD9 CASL Homo sapiens (Human) actin filament bundle assembly [GO:0051017]; actin filament reorganization [GO:0090527]; activation of GTPase activity [GO:0090630]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell migration [GO:0016477]; cilium disassembly [GO:0061523]; cytoskeleton organization [GO:0007010]; integrin-mediated signaling pathway [GO:0007229]; learning or memory [GO:0007611]; lymphocyte migration into lymphoid organs [GO:0097021]; negative regulation of cell migration [GO:0030336]; positive regulation of cell migration [GO:0030335]; positive regulation of dendritic spine maintenance [GO:1902952]; positive regulation of immunological synapse formation [GO:2000522]; positive regulation of lymphocyte chemotaxis [GO:0140131]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of protein localization [GO:1903829]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of actin cytoskeleton organization [GO:0032956]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] basolateral plasma membrane [GO:0016323]; cell cortex [GO:0005938]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; immunological synapse [GO:0001772]; lamellipodium [GO:0030027]; mitotic spindle [GO:0072686]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; spindle [GO:0005819]; spindle pole [GO:0000922] protein tyrosine kinase binding [GO:1990782] 0.9613 -2.5603 TVPDDAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.67717 0 0 0 0 0 Q14515 SPRL1_HUMAN SPARC-like protein 1 (High endothelial venule protein) (Hevin) (MAST 9) SPARCL1 Homo sapiens (Human) anatomical structure development [GO:0048856]; signal transduction [GO:0007165]; synaptic membrane adhesion [GO:0099560] collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978] calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; extracellular matrix binding [GO:0050840] 0.8628 0.083402 EDMSEPQEK 0 0 0 0 0 0 0 0 0 0 14.1525 9.16669 0 11.971 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14517 FAT1_HUMAN "Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]" FAT1 CDHF7 FAT Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] apical plasma membrane [GO:0016324]; cell-cell junction [GO:0005911]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.95898 -1.7807 ALEKNTNVEAR 0 0 0 0 0 0 0 10.3623 0 0 0 0 0 0 0 0 10.8232 0 0 0 0 0 0 0 10.4485 0 11.1996 Q14524 SCN5A_HUMAN Sodium channel protein type 5 subunit alpha (Sodium channel protein cardiac muscle subunit alpha) (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (hH1) SCN5A Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; AV node cell action potential [GO:0086016]; AV node cell to bundle of His cell communication [GO:0086067]; brainstem development [GO:0003360]; bundle of His cell action potential [GO:0086043]; calcium ion import across plasma membrane [GO:0098703]; cardiac conduction system development [GO:0003161]; cardiac muscle cell action potential involved in contraction [GO:0086002]; cardiac muscle contraction [GO:0060048]; cardiac ventricle development [GO:0003231]; cellular response to calcium ion [GO:0071277]; cerebellum development [GO:0021549]; membrane depolarization [GO:0051899]; membrane depolarization during action potential [GO:0086010]; membrane depolarization during atrial cardiac muscle cell action potential [GO:0098912]; membrane depolarization during AV node cell action potential [GO:0086045]; membrane depolarization during bundle of His cell action potential [GO:0086048]; membrane depolarization during cardiac muscle cell action potential [GO:0086012]; membrane depolarization during Purkinje myocyte cell action potential [GO:0086047]; membrane depolarization during SA node cell action potential [GO:0086046]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of action potential [GO:0045760]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of sodium ion transport [GO:0010765]; regulation of atrial cardiac muscle cell membrane depolarization [GO:0060371]; regulation of atrial cardiac muscle cell membrane repolarization [GO:0060372]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of ventricular cardiac muscle cell membrane depolarization [GO:0060373]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; SA node cell action potential [GO:0086015]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]; telencephalon development [GO:0021537]; ventricular cardiac muscle cell action potential [GO:0086005] caveola [GO:0005901]; cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; intercalated disc [GO:0014704]; lateral plasma membrane [GO:0016328]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; T-tubule [GO:0030315]; voltage-gated calcium channel complex [GO:0005891]; voltage-gated sodium channel complex [GO:0001518]; Z disc [GO:0030018] ankyrin binding [GO:0030506]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; fibroblast growth factor binding [GO:0017134]; high voltage-gated calcium channel activity [GO:0008331]; nitric-oxide synthase binding [GO:0050998]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; scaffold protein binding [GO:0097110]; transmembrane transporter binding [GO:0044325]; ubiquitin protein ligase binding [GO:0031625]; voltage-gated sodium channel activity [GO:0005248]; voltage-gated sodium channel activity involved in AV node cell action potential [GO:0086060]; voltage-gated sodium channel activity involved in bundle of His cell action potential [GO:0086061]; voltage-gated sodium channel activity involved in cardiac muscle cell action potential [GO:0086006]; voltage-gated sodium channel activity involved in Purkinje myocyte action potential [GO:0086062]; voltage-gated sodium channel activity involved in SA node cell action potential [GO:0086063] 0.88422 -0.15376 ESLAAIEKRMAEK 12.4433 0 10.3864 0 0 0 0 11.0219 0 0 8.89266 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14526 HIC1_HUMAN Hypermethylated in cancer 1 protein (Hic-1) (Zinc finger and BTB domain-containing protein 29) HIC1 ZBTB29 Homo sapiens (Human) "intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; Wnt signaling pathway [GO:0016055]" chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; histone deacetylase binding [GO:0042826]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.55885 0.53679 LTAEQLSLK 0 0 0 0 0 0 0 0 0 8.73596 0 11.2576 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14549 GBX1_HUMAN Homeobox protein GBX-1 (Gastrulation and brain-specific homeobox protein 1) GBX1 Homo sapiens (Human) adult walking behavior [GO:0007628]; neuron fate commitment [GO:0048663]; proprioception [GO:0019230]; regulation of nervous system development [GO:0051960]; regulation of transcription by RNA polymerase II [GO:0006357]; sensory neuron axon guidance [GO:0097374]; spinal cord motor neuron differentiation [GO:0021522] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.96207 -2.4872 AGNVSSR 0 0 0 9.31415 0 0 0 0 0 0 0 0 11.7393 0 0 0 0 0 0 0 0 0 0 0 0 0 9.743 Q14554 PDIA5_HUMAN Protein disulfide-isomerase A5 (EC 5.3.4.1) (Protein disulfide isomerase-related protein) PDIA5 PDIR Homo sapiens (Human) electron transport chain [GO:0022900]; protein folding [GO:0006457] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789] oxidoreductase activity [GO:0016491]; protein disulfide isomerase activity [GO:0003756]; protein-disulfide reductase activity [GO:0015035] 0.96957 -4.4197 GYPTFHYYHYGK 0 0 0 0 0 0 9.19803 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0391 0 0 0 0 10.0261 10.4176 Q14562 DHX8_HUMAN ATP-dependent RNA helicase DHX8 (EC 3.6.4.13) (DEAH box protein 8) (RNA helicase HRH1) DHX8 DDX8 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]; spliceosomal complex disassembly [GO:0000390]" catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2-type catalytic step 2 spliceosome [GO:0071007] "ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent activity, acting on RNA [GO:0008186]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]" 0.88594 -0.38391 DKQALADQKK 0 0 13.7316 0 0 0 0 0 0 0 0 0 0 11.1696 0 0 0 0 0 0 11.0144 0 0 0 8.85194 0 0 Q14563 SEM3A_HUMAN Semaphorin-3A (Semaphorin III) (Sema III) SEMA3A SEMAD Homo sapiens (Human) apoptotic process [GO:0006915]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; negative chemotaxis [GO:0050919]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of neuron projection development [GO:0010977]; nerve development [GO:0021675]; neural crest cell migration [GO:0001755]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; neuron migration [GO:0001764]; olfactory bulb development [GO:0021772]; positive regulation of JNK cascade [GO:0046330]; positive regulation of neuron migration [GO:2001224]; regulation of axon extension involved in axon guidance [GO:0048841]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory system development [GO:0048880]; sympathetic ganglion development [GO:0061549]; sympathetic nervous system development [GO:0048485]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491] axon [GO:0030424]; dendrite [GO:0030425]; extracellular region [GO:0005576] chemorepellent activity [GO:0045499]; neuropilin binding [GO:0038191]; semaphorin receptor binding [GO:0030215] 0.93265 -1.2623 NEERKEEIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3932 0 0 0 0 0 0 0 0 0 0 0 Q14566 MCM6_HUMAN DNA replication licensing factor MCM6 (EC 3.6.4.12) (p105MCM) MCM6 Homo sapiens (Human) DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via break-induced replication [GO:0000727]; mitotic DNA replication [GO:1902969]; regulation of DNA-templated DNA replication initiation [GO:0030174] "chromosome, telomeric region [GO:0000781]; CMG complex [GO:0071162]; MCM complex [GO:0042555]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]" ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA helicase activity [GO:0003678]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697] 0.94916 -1.3789 DVEQQFK 0 0 0 0 9.46683 0 9.12324 0 14.2341 0 0 0 16.1451 9.03719 0 0 0 0 0 10.683 9.35196 8.77811 10.9694 0 0 0 0 Q14571 ITPR2_HUMAN "Inositol 1,4,5-trisphosphate receptor type 2 (IP3 receptor isoform 2) (IP3R 2) (InsP3R2) (Type 2 inositol 1,4,5-trisphosphate receptor) (Type 2 InsP3 receptor)" ITPR2 Homo sapiens (Human) cellular response to cAMP [GO:0071320]; cellular response to ethanol [GO:0071361]; release of sequestered calcium ion into cytosol [GO:0051209]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165] cell cortex [GO:0005938]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; platelet dense tubular network membrane [GO:0031095]; receptor complex [GO:0043235]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; secretory granule membrane [GO:0030667] "calcium ion transmembrane transporter activity [GO:0015085]; inositol 1,4,5 trisphosphate binding [GO:0070679]; inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220]; phosphatidylinositol binding [GO:0035091]; scaffold protein binding [GO:0097110]; transmembrane transporter binding [GO:0044325]" 0.96888 -3.9024 APFKEKAGEGSMLR 0 12.0089 0 0 9.85342 9.70297 11.0935 0 0 0 0 0 0 0 10.6959 0 0 11.3713 0 0 0 0 0 9.47565 0 0 0 Q14573 ITPR3_HUMAN "Inositol 1,4,5-trisphosphate receptor type 3 (IP3 receptor isoform 3) (IP3R 3) (InsP3R3) (Type 3 inositol 1,4,5-trisphosphate receptor) (Type 3 InsP3 receptor)" ITPR3 Homo sapiens (Human) calcium ion homeostasis [GO:0055074]; G protein-coupled receptor signaling pathway [GO:0007186]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; response to calcium ion [GO:0051592]; sensory perception of bitter taste [GO:0050913]; sensory perception of sweet taste [GO:0050916]; sensory perception of taste [GO:0050909]; sensory perception of umami taste [GO:0050917] apical part of cell [GO:0045177]; brush border [GO:0005903]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nuclear outer membrane [GO:0005640]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; platelet dense tubular network membrane [GO:0031095]; receptor complex [GO:0043235]; sarcoplasmic reticulum [GO:0016529]; secretory granule membrane [GO:0030667] "calcium-release channel activity [GO:0015278]; inositol 1,3,4,5 tetrakisphosphate binding [GO:0043533]; inositol 1,4,5 trisphosphate binding [GO:0070679]; inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220]; inositol hexakisphosphate binding [GO:0000822]; phosphatidylinositol binding [GO:0035091]" 0.96871 -7.7733 FLTCDEYK 0 0 10.8309 0 0 0 0 0 13.1276 11.7943 10.3311 8.5741 0 0 0 0 0 0 0 0 0 0 0 10.2562 0 0 0 Q14574 DSC3_HUMAN Desmocollin-3 (Cadherin family member 3) (Desmocollin-4) (HT-CP) DSC3 CDHF3 DSC4 Homo sapiens (Human) cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; protein stabilization [GO:0050821] cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; desmosome [GO:0030057]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; gamma-catenin binding [GO:0045295] 0.95279 -1.4904 RSFTIWLSDKR 0 10.6998 0 0 0 0 10.0979 0 10.1482 9.4297 10.0326 0 0 0 0 0 0 0 0 0 0 0 9.51477 0 0 0 0 Q14576 ELAV3_HUMAN ELAV-like protein 3 (Hu-antigen C) (HuC) (Paraneoplastic cerebellar degeneration-associated antigen) (Paraneoplastic limbic encephalitis antigen 21) ELAVL3 HUC PLE21 Homo sapiens (Human) cell differentiation [GO:0030154]; nervous system development [GO:0007399] ribonucleoprotein complex [GO:1990904] mRNA 3'-UTR AU-rich region binding [GO:0035925] 0.89852 -0.66672 AINTLNGLK 0 0 0 0 0 0 11.1859 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14582 MAD4_HUMAN Max dimerization protein 4 (Max dimerizer 4) (Class C basic helix-loop-helix protein 12) (bHLHc12) (Max-associated protein 4) (Max-interacting transcriptional repressor MAD4) MXD4 BHLHC12 MAD4 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleoplasm [GO:0005654] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein dimerization activity [GO:0046983]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.86876 0.045276 LEQLSVQSVER 0 0 0 0 0 0 0 0 0 0 0 0 9.7352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14584 ZN266_HUMAN Zinc finger protein 266 (Zinc finger protein HZF1) ZNF266 KIAA2007 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.80853 0.22756 AFTQNSDLTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.46205 0 0 0 Q14585 ZN345_HUMAN Zinc finger protein 345 (Zinc finger protein HZF10) ZNF345 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription by RNA polymerase III [GO:0006359]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383] nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.64729 0.39623 AFGSGSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5697 9.99251 0 10.2747 0 8.25555 0 0 0 0 0 0 Q14586 ZN267_HUMAN Zinc finger protein 267 (Zinc finger protein HZF2) ZNF267 Homo sapiens (Human) nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.69372 0.38328 HIQHQTIHIRENSYSYNK 0 12.5504 0 0 0 0 0 0 11.6283 9.82254 11.4408 9.42333 0 0 10.0524 0 0 0 0 0 0 0 0 9.73356 0 0 10.9106 Q14587 ZN268_HUMAN Zinc finger protein 268 (Zinc finger protein HZF3) ZNF268 Homo sapiens (Human) cell differentiation [GO:0030154]; cellular response to tumor necrosis factor [GO:0071356]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of DNA-templated transcription [GO:0006355]; regulation of mitotic cell cycle [GO:0007346]; regulation of protein heterodimerization activity [GO:0043497] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.43501 0.65618 AFNTKSNLIVHQRTHTGEKPYSCNECGK 0 0 0 0 0 0 0 0 0 10.1787 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14590 ZN235_HUMAN Zinc finger protein 235 (Zinc finger protein 270) (Zinc finger protein 93 homolog) (Zfp-93) (Zinc finger protein HZF6) ZNF235 ZFP93 ZNF270 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.92065 -1.1423 SCKQTQMK 0 9.79894 0 0 0 0 0 0 9.82171 0 0 9.94873 9.61771 0 0 0 0 0 0 0 9.0542 0 0 0 0 0 0 Q14592 ZN460_HUMAN Zinc finger protein 460 (Zinc finger protein 272) (Zinc finger protein HZF8) ZNF460 ZNF272 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.89851 -0.66013 CLECGKAFNCR 0 0 0 0 0 0 0 0 0 8.41282 0 0 0 0 0 10.1717 0 0 0 11.0575 0 0 0 0 0 0 0 Q14593 ZN273_HUMAN Zinc finger protein 273 (Zinc finger protein HZF9) ZNF273 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.76316 0.29666 IIHPEVNPYKCEECGK 0 0 0 0 0 9.75422 9.40212 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14596 NBR1_HUMAN Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein) (Membrane component chromosome 17 surface marker 2) (Neighbor of BRCA1 gene 1 protein) (Protein 1A1-3B) NBR1 1A13B KIAA0049 M17S2 MIG19 Homo sapiens (Human) macroautophagy [GO:0016236]; negative regulation of osteoblast differentiation [GO:0045668]; regulation of bone mineralization [GO:0030500]; regulation of stress-activated MAPK cascade [GO:0032872] autophagosome [GO:0005776]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosome [GO:0005764]; M band [GO:0031430]; membrane [GO:0016020]; mitochondrial intermembrane space [GO:0005758]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; peroxisomal membrane [GO:0005778]; phagophore assembly site [GO:0000407]; receptor complex [GO:0043235] mitogen-activated protein kinase binding [GO:0051019]; ubiquitin binding [GO:0043130]; zinc ion binding [GO:0008270] 0.96975 -3.5251 GSSGLVNSRQK 0 0 0 0 0 0 0 0 0 0 0 8.72288 0 0 0 0 0 0 0 0 0 0 9.7127 0 0 0 0 Q14623 IHH_HUMAN Indian hedgehog protein (IHH) (EC 3.1.-.-) (HHG-2) [Cleaved into: Indian hedgehog protein N-product] IHH Homo sapiens (Human) bone resorption [GO:0045453]; branching involved in blood vessel morphogenesis [GO:0001569]; camera-type eye photoreceptor cell fate commitment [GO:0060220]; cartilage development [GO:0051216]; cell fate specification [GO:0001708]; cell maturation [GO:0048469]; cell-cell signaling [GO:0007267]; chondrocyte differentiation involved in endochondral bone morphogenesis [GO:0003413]; chondrocyte proliferation [GO:0035988]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic digit morphogenesis [GO:0042733]; embryonic pattern specification [GO:0009880]; embryonic skeletal joint development [GO:0072498]; epithelial cell morphogenesis [GO:0003382]; epithelial cell-cell adhesion [GO:0090136]; head morphogenesis [GO:0060323]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; intein-mediated protein splicing [GO:0016539]; liver regeneration [GO:0097421]; maternal process involved in female pregnancy [GO:0060135]; multicellular organism growth [GO:0035264]; negative regulation of alpha-beta T cell differentiation [GO:0046639]; negative regulation of apoptotic process [GO:0043066]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of eye pigmentation [GO:0048074]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; negative regulation of T cell differentiation in thymus [GO:0033085]; neuron development [GO:0048666]; osteoblast differentiation [GO:0001649]; pancreas development [GO:0031016]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autoprocessing [GO:0016540]; proteoglycan metabolic process [GO:0006029]; regulation of growth [GO:0040008]; response to estradiol [GO:0032355]; response to mechanical stimulus [GO:0009612]; retinal pigment epithelium development [GO:0003406]; self proteolysis [GO:0097264]; skeletal system development [GO:0001501]; smooth muscle tissue development [GO:0048745]; smoothened signaling pathway [GO:0007224]; somite development [GO:0061053]; vitelline membrane formation [GO:0030704] endoplasmic reticulum membrane [GO:0005789]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; cholesterol-protein transferase activity [GO:0140853]; patched binding [GO:0005113]; peptidase activity [GO:0008233]; very-low-density lipoprotein particle binding [GO:0034189] 0.92351 -1.0502 LMTQRCKDR 0 0 0 0 0 9.42267 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0579 0 0 Q14624 ITIH4_HUMAN Inter-alpha-trypsin inhibitor heavy chain H4 (ITI heavy chain H4) (ITI-HC4) (Inter-alpha-inhibitor heavy chain 4) (Inter-alpha-trypsin inhibitor family heavy chain-related protein) (IHRP) (Plasma kallikrein sensitive glycoprotein 120) (Gp120) (PK-120) [Cleaved into: 70 kDa inter-alpha-trypsin inhibitor heavy chain H4; 35 kDa inter-alpha-trypsin inhibitor heavy chain H4] ITIH4 IHRP ITIHL1 PK120 PRO1851 Homo sapiens (Human) acute-phase response [GO:0006953]; hyaluronan metabolic process [GO:0030212]; negative regulation of peptidase activity [GO:0010466]; response to cytokine [GO:0034097] blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; platelet dense granule lumen [GO:0031089] endopeptidase inhibitor activity [GO:0004866]; serine-type endopeptidase inhibitor activity [GO:0004867] 0.92355 -1.0365 IPKPEASFSPR 8.8453 0 9.175 0 0 0 0 0 0 0 9.68331 0 0 0 0 0 0 9.72026 0 0 0 0 0 0 0 0 0 Q14626 I11RA_HUMAN Interleukin-11 receptor subunit alpha (IL-11 receptor subunit alpha) (IL-11R subunit alpha) (IL-11R-alpha) (IL-11RA) [Cleaved into: Soluble interleukin-11 receptor subunit alpha (sIL-11R) (sIL-11RA) (sIL11RA)] IL11RA Homo sapiens (Human) cytokine-mediated signaling pathway [GO:0019221]; developmental process [GO:0032502]; head development [GO:0060322]; interleukin-11-mediated signaling pathway [GO:0038154]; positive regulation of cell population proliferation [GO:0008284] external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] interleukin-11 binding [GO:0019970]; interleukin-11 receptor activity [GO:0004921]; transmembrane signaling receptor activity [GO:0004888] 0.89884 -0.58763 TVLGADSQRR 0 0 0 0 0 0 0 0 0 0 11.5798 11.4465 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14643 ITPR1_HUMAN "Inositol 1,4,5-trisphosphate receptor type 1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)" ITPR1 INSP3R1 Homo sapiens (Human) "calcium ion transport [GO:0006816]; cell morphogenesis [GO:0000902]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; epithelial fluid transport [GO:0042045]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; ion channel modulating, G protein-coupled receptor signaling pathway [GO:0099105]; ligand-gated ion channel signaling pathway [GO:1990806]; negative regulation of calcium-mediated signaling [GO:0050849]; phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway [GO:0007207]; positive regulation of insulin secretion [GO:0032024]; post-embryonic development [GO:0009791]; regulation of autophagy [GO:0010506]; release of sequestered calcium ion into cytosol [GO:0051209]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; voluntary musculoskeletal movement [GO:0050882]" calcineurin complex [GO:0005955]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; nuclear inner membrane [GO:0005637]; nucleolus [GO:0005730]; perinuclear region of cytoplasm [GO:0048471]; platelet dense granule membrane [GO:0031088]; platelet dense tubular network [GO:0031094]; platelet dense tubular network membrane [GO:0031095]; postsynaptic density [GO:0014069]; sarcoplasmic reticulum [GO:0016529]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule membrane [GO:0030667]; transport vesicle membrane [GO:0030658] "calcium channel inhibitor activity [GO:0019855]; calcium ion transmembrane transporter activity [GO:0015085]; calcium-release channel activity [GO:0015278]; inositol 1,4,5 trisphosphate binding [GO:0070679]; inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels [GO:0098695]; inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220]; phosphatidylinositol binding [GO:0035091]; protein domain specific binding [GO:0019904]" 0.9698 -5.2713 AKEPTTQITEEVR 0 0 0 0 10.2114 0 0 0 11.0282 0 0 0 10.3637 9.87549 0 0 0 0 0 0 0 0 0 0 9.97757 0 10.8072 Q14644 RASA3_HUMAN Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) RASA3 Homo sapiens (Human) negative regulation of Ras protein signal transduction [GO:0046580]; regulation of GTPase activity [GO:0043087]; signal transduction [GO:0007165] cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829] calcium-release channel activity [GO:0015278]; GTPase activator activity [GO:0005096]; metal ion binding [GO:0046872] 0.96214 -2.5517 DVFRRDSIIGK 0 0 0 0 0 0 0 0 12.6468 0 0 0 0 0 0 0 0 0 0 0 0 11.8445 0 9.79909 0 0 0 Q14654 KCJ11_HUMAN "ATP-sensitive inward rectifier potassium channel 11 (IKATP) (Inward rectifier K(+) channel Kir6.2) (Potassium channel, inwardly rectifying subfamily J member 11)" KCNJ11 Homo sapiens (Human) glucose metabolic process [GO:0006006]; inorganic cation transmembrane transport [GO:0098662]; negative regulation of insulin secretion [GO:0046676]; nervous system process [GO:0050877]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; regulation of insulin secretion [GO:0050796]; regulation of membrane potential [GO:0042391]; regulation of monoatomic ion transmembrane transport [GO:0034765]; response to ATP [GO:0033198]; response to xenobiotic stimulus [GO:0009410] inward rectifying potassium channel [GO:0008282]; plasma membrane [GO:0005886]; T-tubule [GO:0030315] ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; ATP-activated inward rectifier potassium channel activity [GO:0015272]; ATPase-coupled monoatomic cation transmembrane transporter activity [GO:0019829]; calcium channel inhibitor activity [GO:0019855]; potassium ion binding [GO:0030955]; transmembrane transporter binding [GO:0044325]; voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential [GO:0099508]; voltage-gated potassium channel activity [GO:0005249] 0.95498 -1.5216 SVPMAKAKPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0965 0 Q14656 TM187_HUMAN Transmembrane protein 187 (Protein ITBA1) TMEM187 CXorf12 DXS9878E ITBA1 Homo sapiens (Human) membrane [GO:0016020]; transport vesicle [GO:0030133] 0.58642 0.46795 LCDHQLAR 0 0 0 0 0 0 0 0 0 9.11723 0 8.48123 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14657 LAGE3_HUMAN EKC/KEOPS complex subunit LAGE3 (L antigen family member 3) (Protein ESO-3) (Protein ITBA2) LAGE3 DXS9879E ESO3 ITBA2 Homo sapiens (Human) tRNA processing [GO:0008033]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525] cytoplasm [GO:0005737]; EKC/KEOPS complex [GO:0000408]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.91412 -0.80029 RDADADAGGGADGGDGR 0 0 10.4242 0 0 0 0 10.7782 10.7142 10.9767 11.0782 10.9073 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14667 BLTP2_HUMAN Bridge-like lipid transfer protein family member 2 (Antigen MLAA-22) (Breast cancer-overexpressed gene 1 protein) (Protein hobbit homolog) BLTP2 BCOX1 KIAA0100 Homo sapiens (Human) endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-plasma membrane contact site [GO:0140268]; mitochondrial membrane [GO:0031966]; plasma membrane [GO:0005886] phosphatidylinositol binding [GO:0035091] 0.88334 -0.17686 AFRSENLNLSIK 0 8.95411 0 0 0 0 0 9.24615 0 0 9.09373 0 0 0 0 0 0 9.7468 0 0 0 0 0 0 0 0 0 Q14669 TRIPC_HUMAN E3 ubiquitin-protein ligase TRIP12 (EC 2.3.2.26) (E3 ubiquitin-protein ligase for Arf) (ULF) (HECT-type E3 ubiquitin transferase TRIP12) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12) TRIP12 KIAA0045 ULF Homo sapiens (Human) DNA damage response [GO:0006974]; DNA repair [GO:0006281]; DNA repair-dependent chromatin remodeling [GO:0140861]; heterochromatin boundary formation [GO:0033696]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; regulation of double-strand break repair [GO:2000779]; regulation of embryonic development [GO:0045995]; ubiquitin-dependent protein catabolic process [GO:0006511] cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] nuclear thyroid hormone receptor binding [GO:0046966]; ubiquitin protein ligase activity [GO:0061630] 0.96876 -8.3857 ANTSERQKTGQVPK 0 0 0 0 0 0 0 0 9.1758 12.2948 0 0 0 0 0 11.8807 0 0 0 0 0 0 0 9.08164 11.0051 0 9.10685 Q14671 PUM1_HUMAN Pumilio homolog 1 (HsPUM) (Pumilio-1) PUM1 KIAA0099 PUMH1 Homo sapiens (Human) adult locomotory behavior [GO:0008344]; miRNA processing [GO:0035196]; mRNA destabilization [GO:0061157]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; post-transcriptional gene silencing [GO:0016441]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of cell cycle [GO:0051726]; regulation of chromosome segregation [GO:0051983]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of mRNA stability [GO:0043488]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863] cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932] miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723] 0.91494 -0.78081 DSLTGSSDLYKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3147 0 Q14676 MDC1_HUMAN Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1) MDC1 KIAA0170 NFBD1 Homo sapiens (Human) DNA repair [GO:0006281]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261] chromosome [GO:0005694]; focal adhesion [GO:0005925]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.96985 -5.0404 GLLNCKMPPAEK 0 0 0 0 0 0 0 0 0 0 0 9.81113 0 0 0 0 0 0 0 0 11.1833 10.5696 0 10.799 9.53924 0 0 Q14678 KANK1_HUMAN KN motif and ankyrin repeat domain-containing protein 1 (Ankyrin repeat domain-containing protein 15) (Kidney ankyrin repeat-containing protein) KANK1 ANKRD15 KANK KIAA0172 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell population proliferation [GO:0008283]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of cell migration [GO:0030336]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lamellipodium morphogenesis [GO:2000393]; negative regulation of neuron projection development [GO:0010977]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of ruffle assembly [GO:1900028]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; podocyte cell migration [GO:0090521]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Wnt signaling pathway [GO:0030177]; positive regulation of wound healing [GO:0090303]; regulation of establishment of cell polarity [GO:2000114]; regulation of Rho protein signal transduction [GO:0035023] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587] beta-catenin binding [GO:0008013] 0.95598 -1.5946 ALTSKDMR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.061 0 0 0 9.74359 0 0 0 0 0 0 0 Q14679 TTLL4_HUMAN Tubulin monoglutamylase TTLL4 (EC 6.3.2.-) (Protein monoglutamylase TTLL4) (Tubulin--tyrosine ligase-like protein 4) TTLL4 KIAA0173 Homo sapiens (Human) microtubule cytoskeleton organization [GO:0000226]; peptidyl-glutamic acid modification [GO:0018200]; protein polyglutamylation [GO:0018095]; regulation of blastocyst development [GO:0120222] 9+0 non-motile cilium [GO:0097731]; ciliary basal body [GO:0036064]; cilium [GO:0005929]; cytosol [GO:0005829]; microtubule [GO:0005874] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein-glutamic acid ligase activity [GO:0070739]; tubulin binding [GO:0015631]; tubulin-glutamic acid ligase activity [GO:0070740] 0.96962 -3.1718 IQPVSWHHSGGTGDCAPQPVDHK 12.7525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7845 0 0 Q14680 MELK_HUMAN Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase Eg3) (pEg3 kinase) (Protein kinase PK38) (hPK38) (Tyrosine-protein kinase MELK) (EC 2.7.10.2) MELK KIAA0175 Homo sapiens (Human) apoptotic process [GO:0006915]; cell population proliferation [GO:0008283]; G2/M transition of mitotic cell cycle [GO:0000086]; hemopoiesis [GO:0030097]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; neural precursor cell proliferation [GO:0061351]; positive regulation of apoptotic process [GO:0043065]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468] cell cortex [GO:0005938]; cytoplasm [GO:0005737]; membrane [GO:0016020]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; lipid binding [GO:0008289]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.92692 -1.2197 ENVYTPKSAVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.32238 0 0 Q14681 KCTD2_HUMAN BTB/POZ domain-containing protein KCTD2 (Potassium channel tetramerization domain-containing protein 2) KCTD2 KIAA0176 Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein homooligomerization [GO:0051260] Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737] cullin family protein binding [GO:0097602]; protein-containing complex binding [GO:0044877] 0.86981 0.041164 AGGGGAAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.85699 0 0 0 0 0 0 0 Q14683 SMC1A_HUMAN Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1-alpha) (SMC-1A) (Sb1.8) SMC1A DXS423E KIAA0178 SB1.8 SMC1 SMC1L1 Homo sapiens (Human) cell division [GO:0051301]; DNA repair [GO:0006281]; establishment of meiotic sister chromatid cohesion [GO:0034089]; establishment of mitotic sister chromatid cohesion [GO:0034087]; meiotic cell cycle [GO:0051321]; mitotic sister chromatid cohesion [GO:0007064]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly [GO:0090307]; response to DNA damage checkpoint signaling [GO:0072423]; response to radiation [GO:0009314]; sister chromatid cohesion [GO:0007062]; somatic stem cell population maintenance [GO:0035019] "chromosome [GO:0005694]; chromosome, centromeric region [GO:0000775]; cohesin complex [GO:0008278]; condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; kinetochore [GO:0000776]; meiotic cohesin complex [GO:0030893]; mitotic spindle pole [GO:0097431]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]" ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; mediator complex binding [GO:0036033]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723] 0.96924 -4.8582 AEIMESIK 0 0 0 0 0 0 0 0 0 0 8.84188 0 0 0 10.194 0 10.9219 9.0483 0 9.23513 8.19795 0 8.60766 0 10.3354 0 9.42673 Q14684 RRP1B_HUMAN Ribosomal RNA processing protein 1 homolog B (RRP1-like protein B) RRP1B KIAA0179 Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to virus [GO:0098586]; mRNA processing [GO:0006397]; negative regulation of GTPase activity [GO:0034260]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of apoptotic process [GO:0043065]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]; rRNA processing [GO:0006364] "chromosome [GO:0005694]; cytosol [GO:0005829]; euchromatin [GO:0000791]; granular component [GO:0001652]; heterochromatin [GO:0000792]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; preribosome, small subunit precursor [GO:0030688]" RNA binding [GO:0003723]; transcription coactivator activity [GO:0003713] 0.90797 -0.73932 LLEMTSRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7823 0 0 0 0 0 0 0 0 0 0 0 Q14686 NCOA6_HUMAN "Nuclear receptor coactivator 6 (Activating signal cointegrator 2) (ASC-2) (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Nuclear receptor-activating protein, 250 kDa) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Thyroid hormone receptor-binding protein)" NCOA6 AIB3 KIAA0181 RAP250 TRBP Homo sapiens (Human) brain development [GO:0007420]; DNA damage response [GO:0006974]; DNA-templated transcription initiation [GO:0006352]; heart development [GO:0007507]; histone H3-K4 methylation [GO:0051568]; myeloid cell differentiation [GO:0030099]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to hormone [GO:0009725] cytosol [GO:0005829]; histone methyltransferase complex [GO:0035097]; intracellular membrane-bounded organelle [GO:0043231]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; nuclear estrogen receptor binding [GO:0030331]; nuclear receptor coactivator activity [GO:0030374]; nuclear retinoid X receptor binding [GO:0046965]; nuclear thyroid hormone receptor binding [GO:0046966]; transcription coactivator activity [GO:0003713] 0.96728 -2.8055 AIGQAPSNLTMNPSNFATPQTHK 0 0 0 0 0 0 0 0 10.6674 0 0 0 0 9.87418 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14687 GSE1_HUMAN Genetic suppressor element 1 GSE1 KIAA0182 Homo sapiens (Human) 0.95521 -1.5535 LDLEERR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.95646 Q14689 DIP2A_HUMAN Disco-interacting protein 2 homolog A (DIP2 homolog A) (EC 6.2.1.1) DIP2A C21orf106 DIP2 KIAA0184 Homo sapiens (Human) acetyl-CoA biosynthetic process [GO:0006085]; dendritic spine morphogenesis [GO:0060997]; negative regulation of gene expression [GO:0010629]; positive regulation of peptidyl-lysine acetylation [GO:2000758] cell surface [GO:0009986]; dendritic spine [GO:0043197]; membrane [GO:0016020]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886] acetate-CoA ligase activity [GO:0003987] 0.041215 1.489 AVLSMNGLSYGVIR 17.3161 17.221 16.9916 15.9495 16.2775 16.0586 16.878 17.1783 17.0867 16.3687 16.5905 16.8382 15.85 16.0788 16.1809 16.9372 17.4549 16.7209 12.9051 0 0 12.3493 12.3307 12.402 0 0 9.98684 Q14690 RRP5_HUMAN Protein RRP5 homolog (NF-kappa-B-binding protein) (NFBP) (Programmed cell death protein 11) PDCD11 KIAA0185 Homo sapiens (Human) rRNA processing [GO:0006364] cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; small-subunit processome [GO:0032040] NF-kappaB binding [GO:0051059]; RNA binding [GO:0003723] 0.96994 -5.2402 AEKELSR 18.1614 0 0 15.1633 15.1218 14.2228 18.1907 18.1557 0 11.7727 11.8528 18.6616 14.7404 14.75 14.9697 15.9981 16.3925 16.2693 12.1857 11.1595 11.0383 0 11.2279 11.021 11.8448 0 0 Q14691 PSF1_HUMAN DNA replication complex GINS protein PSF1 (GINS complex subunit 1) GINS1 KIAA0186 PSF1 Homo sapiens (Human) DNA strand elongation involved in mitotic DNA replication [GO:1902983]; DNA unwinding involved in DNA replication [GO:0006268]; inner cell mass cell proliferation [GO:0001833]; positive regulation of DNA primase activity [GO:1903934]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264] CMG complex [GO:0071162]; cytoplasm [GO:0005737]; GINS complex [GO:0000811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.93371 -1.2902 RCTVAYLYDRLLR 9.31309 9.21888 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14692 BMS1_HUMAN Ribosome biogenesis protein BMS1 homolog (Ribosome assembly protein BMS1 homolog) BMS1 BMS1L KIAA0187 Homo sapiens (Human) "endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000479]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosomal small subunit biogenesis [GO:0042274]" 90S preribosome [GO:0030686]; chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040] ATP binding [GO:0005524]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; RNA binding [GO:0003723]; U3 snoRNA binding [GO:0034511] 0.9509 -1.4005 DPIIFSVGWRR 10.3869 0 0 0 0 0 0 9.55038 9.35579 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14697 GANAB_HUMAN Neutral alpha-glucosidase AB (EC 3.2.1.207) (Alpha-glucosidase 2) (Glucosidase II subunit alpha) GANAB G2AN KIAA0088 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; N-glycan processing [GO:0006491] endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; glucosidase II complex [GO:0017177]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020] "alpha-glucosidase activity [GO:0090599]; carbohydrate binding [GO:0030246]; glucan 1,3-alpha-glucosidase activity [GO:0033919]; RNA binding [GO:0003723]" 0 19.68 AFFAGSQR 8.68289 8.64202 8.78454 0 0 0 10.823 10.8376 10.3688 0 11.84 0 9.8961 9.95137 10.1478 10.187 11.0575 0 12.1823 12.4197 12.2883 11.0051 11.514 11.9699 13.0251 12.8715 12.5089 Q14703 MBTP1_HUMAN Membrane-bound transcription factor site-1 protease (EC 3.4.21.112) (Endopeptidase S1P) (Subtilisin/kexin-isozyme 1) (SKI-1) MBTPS1 KIAA0091 S1P SKI1 Homo sapiens (Human) ATF6-mediated unfolded protein response [GO:0036500]; cholesterol metabolic process [GO:0008203]; endoplasmic reticulum unfolded protein response [GO:0030968]; lysosome organization [GO:0007040]; membrane protein intracellular domain proteolysis [GO:0031293]; protein maturation [GO:0051604]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of vesicle-mediated transport [GO:0060627]; response to endoplasmic reticulum stress [GO:0034976] endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795] serine-type endopeptidase activity [GO:0004252] 0.87107 0.030597 IVLYGDSNCLDDSHRQK 0 0 0 0 0 0 0 0 0 0 0 10.36 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14739 LBR_HUMAN Delta(14)-sterol reductase LBR (Delta-14-SR) (EC 1.3.1.70) (3-beta-hydroxysterol Delta (14)-reductase) (C-14 sterol reductase) (C14SR) (Integral nuclear envelope inner membrane protein) (LMN2R) (Lamin-B receptor) (Sterol C14-reductase) LBR Homo sapiens (Human) cholesterol biosynthetic process [GO:0006695]; neutrophil differentiation [GO:0030223] cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nucleus [GO:0005634] chromo shadow domain binding [GO:0070087]; delta14-sterol reductase activity [GO:0050613]; DNA binding [GO:0003677]; lamin binding [GO:0005521]; NADPH binding [GO:0070402]; RNA binding [GO:0003723] 0.96918 -3.4729 EIDSKEEK 0 9.58802 0 0 0 0 0 0 10.0479 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14764 MVP_HUMAN Major vault protein (MVP) (Lung resistance-related protein) MVP LRP Homo sapiens (Human) ERBB signaling pathway [GO:0038127]; mRNA transport [GO:0051028]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein tyrosine kinase activity [GO:0061099]; protein transport [GO:0015031] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nuclear pore [GO:0005643]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774] identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903] 0 8.6772 ATEEFIIR 0 0 0 0 0 0 0 0 0 10.6075 8.88261 9.75171 9.89517 0 0 0 0 8.60544 9.28997 0 0 0 0 0 0 0 0 Q14765 STAT4_HUMAN Signal transducer and activator of transcription 4 STAT4 Homo sapiens (Human) cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; interleukin-12-mediated signaling pathway [GO:0035722]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of cell population proliferation [GO:0042127]; regulation of transcription by RNA polymerase II [GO:0006357]; response to peptide hormone [GO:0043434]; T-helper 1 cell differentiation [GO:0045063] chromatin [GO:0000785]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.95531 -1.6035 DKMPGTFLLR 13.2157 0 0 0 0 0 16.0694 0 0 0 0 0 0 0 0 0 13.7578 0 0 0 0 0 0 0 10.0752 10.0189 0 Q14766 LTBP1_HUMAN Latent-transforming growth factor beta-binding protein 1 (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1) LTBP1 Homo sapiens (Human) regulation of transforming growth factor beta activation [GO:1901388]; sequestering of TGFbeta in extracellular matrix [GO:0035583] collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; microfibril [GO:0001527]; protein-containing complex [GO:0032991] calcium ion binding [GO:0005509]; microfibril binding [GO:0050436]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor activity [GO:0005024] 0.96943 -4.0618 ALPGLSK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1202 0 0 0 0 0 0 0 0 0 0 0 8.76699 0 Q14774 HLX_HUMAN H2.0-like homeobox protein (Homeobox protein HB24) (Homeobox protein HLX1) HLX HLX1 Homo sapiens (Human) embryonic digestive tract morphogenesis [GO:0048557]; enteric nervous system development [GO:0048484]; epithelial cell proliferation [GO:0050673]; liver development [GO:0001889]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; organ growth [GO:0035265]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of organ growth [GO:0046622]; positive regulation of T-helper 1 cell differentiation [GO:0045627]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]; T-helper 1 cell differentiation [GO:0045063]; T-helper 2 cell differentiation [GO:0045064] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific DNA binding [GO:0043565]" 0.78447 0.25372 ILSAEFDPK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.9612 0 0 9.78423 0 0 0 0 0 0 0 0 0 0 Q14781 CBX2_HUMAN Chromobox protein homolog 2 CBX2 Homo sapiens (Human) cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; development of primary sexual characteristics [GO:0045137]; negative regulation of transcription by RNA polymerase II [GO:0000122] euchromatin [GO:0000791]; heterochromatin [GO:0000792]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PcG protein complex [GO:0031519]; PRC1 complex [GO:0035102] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; methylated histone binding [GO:0035064] 0.92394 -1.036 GELGMSPPGSK 0 0 0 0 0 0 0 0 0 0 0 9.62086 0 0 0 0 0 10.1202 0 0 0 0 0 0 0 0 0 Q14789 GOGB1_HUMAN Golgin subfamily B member 1 (372 kDa Golgi complex-associated protein) (GCP372) (Giantin) (Macrogolgin) GOLGB1 Homo sapiens (Human) Golgi organization [GO:0007030]; protein localization to pericentriolar material [GO:1905793]; regulation of DNA-templated transcription [GO:0006355] cis-Golgi network [GO:0005801]; cytosol [GO:0005829]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; membrane [GO:0016020] RNA binding [GO:0003723]; sequence-specific DNA binding [GO:0043565] 0.96893 -7.614 AQLQEYQDK 0 12.8521 0 11.632 12.658 11.3138 11.0711 0 16.1514 9.58959 0 0 12.6665 8.68689 10.5394 9.10221 0 0 0 0 0 0 0 0 12.8415 0 12.7939 Q14790 CASP8_HUMAN Caspase-8 (CASP-8) (EC 3.4.22.61) (Apoptotic cysteine protease) (Apoptotic protease Mch-5) (CAP4) (FADD-homologous ICE/ced-3-like protease) (FADD-like ICE) (FLICE) (ICE-like apoptotic protease 5) (MORT1-associated ced-3 homolog) (MACH) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10] CASP8 MCH5 Homo sapiens (Human) activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; B cell activation [GO:0042113]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; heart development [GO:0007507]; macrophage differentiation [GO:0030225]; natural killer cell activation [GO:0030101]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of necroptotic process [GO:0060546]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of neuron death [GO:1901216]; positive regulation of proteolysis [GO:0045862]; protein maturation [GO:0051604]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; pyroptosis [GO:0070269]; regulation of cytokine production [GO:0001817]; regulation of innate immune response [GO:0045088]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to antibiotic [GO:0046677]; response to cobalt ion [GO:0032025]; response to cold [GO:0009409]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; self proteolysis [GO:0097264]; syncytiotrophoblast cell differentiation involved in labyrinthine layer development [GO:0060715]; T cell activation [GO:0042110]; TRAIL-activated apoptotic signaling pathway [GO:0036462] caspase complex [GO:0008303]; CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ripoptosome [GO:0097342] cysteine-type endopeptidase activity [GO:0004197]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097199]; cysteine-type peptidase activity [GO:0008234]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625] 0.9469 -1.3554 SELRSFKFLLQEEISK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14.3538 0 0 0 Q147U1 ZN846_HUMAN Zinc finger protein 846 ZNF846 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.88411 -0.27981 TKGSPLLQDISAER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.69973 0 0 0 Q147U7 SMCO1_HUMAN Single-pass membrane and coiled-coil domain-containing protein 1 (Single-pass membrane protein with coiled-coil domains 1) SMCO1 C3orf43 Homo sapiens (Human) membrane [GO:0016020] 0.9621 -2.5461 AEHYTAK 0 0 0 8.59861 0 0 0 0 0 0 0 9.63807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14802 FXYD3_HUMAN FXYD domain-containing ion transport regulator 3 (Chloride conductance inducer protein Mat-8) (Mammary tumor 8 kDa protein) (Phospholemman-like) (Sodium/potassium-transporting ATPase subunit FXYD3) FXYD3 MAT8 PLML Homo sapiens (Human) chloride transport [GO:0006821]; potassium ion transport [GO:0006813]; regulation of catalytic activity [GO:0050790]; regulation of sodium ion transmembrane transporter activity [GO:2000649]; sodium ion transport [GO:0006814] endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] ATPase binding [GO:0051117]; chloride channel activity [GO:0005254]; sodium channel regulator activity [GO:0017080] 0.87132 0.062559 SGHHPGETPPLITPGSAQS 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6165 0 0 Q14807 KIF22_HUMAN Kinesin-like protein KIF22 (Kinesin-like DNA-binding protein) (Kinesin-like protein 4) KIF22 KID KNSL4 Homo sapiens (Human) DNA repair [GO:0006281]; metaphase plate congression [GO:0051310]; microtubule-based movement [GO:0007018]; mitotic cell cycle [GO:0000278]; mitotic metaphase plate congression [GO:0007080]; sister chromatid cohesion [GO:0007062] chromatin [GO:0000785]; cytosol [GO:0005829]; kinesin complex [GO:0005871]; kinetochore [GO:0000776]; microtubule [GO:0005874]; mitotic spindle [GO:0072686]; nuclear speck [GO:0016607]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA binding [GO:0003677]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777] 0.96346 -2.1178 DLEIERLK 0 0 10.0739 0 0 0 0 0 0 0 0 13.9762 0 9.14423 0 0 0 0 0 0 0 0 0 0 0 0 9.30608 Q14831 GRM7_HUMAN Metabotropic glutamate receptor 7 (mGluR7) GRM7 GPRC1G MGLUR7 Homo sapiens (Human) "adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway [GO:0007196]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; axon development [GO:0061564]; chemical synaptic transmission [GO:0007268]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; glycosylation [GO:0070085]; negative regulation of glutamate secretion [GO:0014050]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of sound [GO:0007605]" asymmetric synapse [GO:0032279]; axon [GO:0030424]; cell cortex [GO:0005938]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic active zone [GO:0048786]; receptor complex [GO:0043235] adenylate cyclase inhibitor activity [GO:0010855]; calcium ion binding [GO:0005509]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; group III metabotropic glutamate receptor activity [GO:0001642]; PDZ domain binding [GO:0030165]; protein dimerization activity [GO:0046983]; serine binding [GO:0070905] 0.73261 0.32916 GPSGVPCGDIK 0 0 0 0 0 0 9.78782 0 0 0 0 0 0 0 0 0 0 0 10.2167 0 0 0 0 0 0 0 0 Q14832 GRM3_HUMAN Metabotropic glutamate receptor 3 (mGluR3) GRM3 GPRC1C MGLUR3 Homo sapiens (Human) "chemical synaptic transmission [GO:0007268]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gene expression [GO:0010467]; negative regulation of adenylate cyclase activity [GO:0007194]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of synaptic transmission, glutamatergic [GO:0051966]" astrocyte projection [GO:0097449]; axon [GO:0030424]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734] calcium channel regulator activity [GO:0005246]; G protein-coupled receptor activity [GO:0004930]; glutamate receptor activity [GO:0008066]; group II metabotropic glutamate receptor activity [GO:0001641]; scaffold protein binding [GO:0097110] 0.29827 0.81054 EIKIEGDLVLGGLFPINEK 9.67234 0 9.45642 0 0 0 0 0 10.0808 0 0 0 0 9.02287 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14833 GRM4_HUMAN Metabotropic glutamate receptor 4 (mGluR4) GRM4 GPRC1D MGLUR4 Homo sapiens (Human) "adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway [GO:0007196]; chemical synaptic transmission [GO:0007268]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; neurotransmitter secretion [GO:0007269]; positive regulation of MAPK cascade [GO:0043410]; regulation of neuron apoptotic process [GO:0043523]; regulation of synaptic transmission, glutamatergic [GO:0051966]" cytoplasmic vesicle [GO:0031410]; plasma membrane [GO:0005886]; presynapse [GO:0098793] adenylate cyclase inhibiting G protein-coupled glutamate receptor activity [GO:0001640]; G protein-coupled receptor activity [GO:0004930]; glutamate receptor activity [GO:0008066] 0.95212 -1.3863 AVVTAATMSNK 0 0 0 0 0 0 0 0 0 0 11.4272 0 0 0 0 0 0 0 0 0 0 11.514 0 0 0 0 0 Q14839 CHD4_HUMAN Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta) CHD4 Homo sapiens (Human) chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone deacetylation [GO:0016575]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cell fate specification [GO:0042659]; regulation of stem cell differentiation [GO:2000736]; regulation of synapse assembly [GO:0051963]; terminal button organization [GO:0072553] "centrosome [GO:0005813]; cerebellar granule cell to Purkinje cell synapse [GO:0150048]; chromatin [GO:0000785]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NuRD complex [GO:0016581]; protein-containing complex [GO:0032991]; RNA polymerase II transcription regulator complex [GO:0090575]; site of DNA damage [GO:0090734]" ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent chromatin remodeler activity [GO:0140658]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; helicase activity [GO:0004386]; histone binding [GO:0042393]; histone deacetylase binding [GO:0042826]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription coregulator binding [GO:0001221]; transcription corepressor activity [GO:0003714]; zinc ion binding [GO:0008270] 0.96397 -2.2117 AEVKERTEEPMETEPK 0 0 0 0 0 0 9.67119 0 0 0 0 9.99393 0 0 10.3923 10.896 0 0 0 0 0 0 0 0 0 0 0 Q14847 LASP1_HUMAN LIM and SH3 domain protein 1 (LASP-1) (Metastatic lymph node gene 50 protein) (MLN 50) LASP1 MLN50 Homo sapiens (Human) monoatomic ion transport [GO:0006811] cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; focal adhesion [GO:0005925] actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; metal ion binding [GO:0046872]; monoatomic ion transmembrane transporter activity [GO:0015075] 0.065606 1.2944 EPAAPVSIQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5196 0 0 0 0 9.2968 0 0 0 0 Q14849 STAR3_HUMAN StAR-related lipid transfer protein 3 (Metastatic lymph node gene 64 protein) (MLN 64) (Protein CAB1) (START domain-containing protein 3) (StARD3) STARD3 CAB1 MLN64 Homo sapiens (Human) cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; lipid metabolic process [GO:0006629]; mitochondrial transport [GO:0006839]; progesterone biosynthetic process [GO:0006701]; steroid metabolic process [GO:0008202]; vesicle tethering to endoplasmic reticulum [GO:0099044] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum-endosome membrane contact site [GO:0140284]; endosome [GO:0005768]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; organelle membrane contact site [GO:0044232] cholesterol binding [GO:0015485]; cholesterol transfer activity [GO:0120020]; protein homodimerization activity [GO:0042803] 0.95569 -1.5956 ELTRDLER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.19446 0 0 0 0 0 0 0 0 Q14865 ARI5B_HUMAN AT-rich interactive domain-containing protein 5B (ARID domain-containing protein 5B) (MRF1-like protein) (Modulator recognition factor 2) (MRF-2) ARID5B DESRT MRF2 Homo sapiens (Human) adipose tissue development [GO:0060612]; adrenal gland development [GO:0030325]; cell development [GO:0048468]; cellular response to leukemia inhibitory factor [GO:1990830]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; fibroblast migration [GO:0010761]; kidney development [GO:0001822]; liver development [GO:0001889]; male gonad development [GO:0008584]; multicellular organism growth [GO:0035264]; muscle organ morphogenesis [GO:0048644]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; post-embryonic development [GO:0009791]; regulation of transcription by RNA polymerase II [GO:0006357]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705] nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; transcription cis-regulatory region binding [GO:0000976]; transcription coactivator activity [GO:0003713] 0.96962 -5.0481 EALLKYR 0 12.2876 10.0178 0 0 0 0 10.2184 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14894 CRYM_HUMAN Ketimine reductase mu-crystallin (EC 1.5.1.25) (NADP-regulated thyroid-hormone-binding protein) CRYM THBP Homo sapiens (Human) lysine catabolic process [GO:0006554]; negative regulation of transcription by RNA polymerase II [GO:0000122]; sensory perception of sound [GO:0007605]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; peroxisomal matrix [GO:0005782] NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; thiomorpholine-carboxylate dehydrogenase activity [GO:0047127]; thyroid hormone binding [GO:0070324]; transcription corepressor activity [GO:0003714] 0.93931 -1.3185 FADTVQGEVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.57737 0 0 Q14914 PTGR1_HUMAN Prostaglandin reductase 1 (PRG-1) (15-oxoprostaglandin 13-reductase) (EC 1.3.1.48) (Dithiolethione-inducible gene 1 protein) (D3T-inducible gene 1 protein) (DIG-1) (Leukotriene B4 12-hydroxydehydrogenase) (NAD(P)H-dependent alkenal/one oxidoreductase) (EC 1.3.1.74) PTGR1 LTB4DH Homo sapiens (Human) leukotriene B4 metabolic process [GO:0036102]; leukotriene metabolic process [GO:0006691]; lipoxin A4 metabolic process [GO:2001302]; prostaglandin metabolic process [GO:0006693]; response to antineoplastic agent [GO:0097327] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062] 13-lipoxin reductase activity [GO:0036185]; 13-prostaglandin reductase activity [GO:0036132]; 15-oxoprostaglandin 13-oxidase activity [GO:0047522]; 2-alkenal reductase (NADP+) activity [GO:0035798]; leukotriene B4 12-hydroxy dehydrogenase activity [GO:0097257] 0.78793 0.24807 LGFDVVFNYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.72806 9.6862 0 0 0 0 Q14929 ZN169_HUMAN Zinc finger protein 169 ZNF169 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.88995 -0.45675 ISRTFFSPHQGDPVEWVEGNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.89689 0 0 0 Q14934 NFAC4_HUMAN "Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T-cell transcription factor NFAT3) (NF-AT3)" NFATC4 NFAT3 Homo sapiens (Human) brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; branching involved in blood vessel morphogenesis [GO:0001569]; calcineurin-NFAT signaling cascade [GO:0033173]; cellular respiration [GO:0045333]; cellular response to lithium ion [GO:0071285]; cellular response to UV [GO:0034644]; dendrite morphogenesis [GO:0048813]; heart development [GO:0007507]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; negative regulation of chromatin binding [GO:0035562]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of miRNA transcription [GO:1902894]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of synapse maturation [GO:2000297]; negative regulation of Wnt signaling pathway [GO:0030178]; neuron apoptotic process [GO:0051402]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of transcription by RNA polymerase II [GO:0006357]; synapse maturation [GO:0060074]; transcription by RNA polymerase II [GO:0006366]; vascular associated smooth muscle cell development [GO:0097084] chromatin [GO:0000785]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; peroxisome proliferator activated receptor binding [GO:0042975]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.69779 0.3748 GAASCEDEELEFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.29506 Q14938 NFIX_HUMAN Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein) NFIX Homo sapiens (Human) DNA replication [GO:0006260]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.89975 -0.68933 AFSYTWFNLQARK 0 0 0 0 0 0 0 0 11.1634 0 11.47 0 0 0 0 0 0 0 11.454 0 0 0 0 0 0 0 0 Q14940 SL9A5_HUMAN Sodium/hydrogen exchanger 5 (Na(+)/H(+) exchanger 5) (NHE-5) (Solute carrier family 9 member 5) SLC9A5 NHE5 Homo sapiens (Human) monoatomic ion transport [GO:0006811]; potassium ion transmembrane transport [GO:0071805]; regulation of intracellular pH [GO:0051453]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725] dendritic spine membrane [GO:0032591]; focal adhesion [GO:0005925]; membrane [GO:0016020]; neuron spine [GO:0044309]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; recycling endosome membrane [GO:0055038]; synapse [GO:0045202] arrestin family protein binding [GO:1990763]; potassium:proton antiporter activity [GO:0015386]; sodium:proton antiporter activity [GO:0015385] 0.89849 -0.64864 EVFQQNMKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1713 10.4716 0 Q14964 RB39A_HUMAN Ras-related protein Rab-39A (Rab-39) RAB39A RAB39 Homo sapiens (Human) autophagy [GO:0006914]; phagosome acidification [GO:0090383]; phagosome-lysosome fusion [GO:0090385]; protein transport [GO:0015031]; Rab protein signal transduction [GO:0032482]; vesicle-mediated transport [GO:0016192] cytosol [GO:0005829]; Golgi membrane [GO:0000139]; lysosome [GO:0005764]; phagocytic vesicle [GO:0045335]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886] GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.93266 -1.2856 LQLWDTAGQER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2166 0 Q14966 ZN638_HUMAN Zinc finger protein 638 (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL-associated antigen se33-1) (Nuclear protein 220) (Zinc finger matrin-like protein) ZNF638 NP220 ZFML Homo sapiens (Human) regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] double-stranded DNA binding [GO:0003690]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270] 0.968 -2.8867 ALEDVVQR 0 0 10.8411 0 0 0 9.21827 0 0 11.4693 11.1015 11.3865 0 9.96453 11.7303 10.2936 10.401 10.3 0 0 0 8.96495 0 0 0 0 0 Q14974 IMB1_HUMAN Importin subunit beta-1 (Importin-90) (Karyopherin subunit beta-1) (Nuclear factor p97) (Pore targeting complex 97 kDa subunit) (PTAC97) KPNB1 NTF97 Homo sapiens (Human) astral microtubule organization [GO:0030953]; establishment of mitotic spindle localization [GO:0040001]; establishment of protein localization [GO:0045184]; mitotic chromosome movement towards spindle pole [GO:0007079]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus [GO:0006606]; Ran protein signal transduction [GO:0031291]; ribosomal protein import into nucleus [GO:0006610]; RNA import into nucleus [GO:0006404] cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; endoplasmic reticulum tubular network [GO:0071782]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; NLS-dependent protein nuclear import complex [GO:0042564]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; specific granule lumen [GO:0035580] enzyme binding [GO:0019899]; Hsp90 protein binding [GO:0051879]; importin-alpha family protein binding [GO:0061676]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; small GTPase binding [GO:0031267]; zinc ion binding [GO:0008270] 0 5.8622 LELEAAQK 0 0 0 0 0 0 0 9.92865 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14978 NOLC1_HUMAN Nucleolar and coiled-body phosphoprotein 1 (140 kDa nucleolar phosphoprotein) (Nopp140) (Hepatitis C virus NS5A-transactivated protein 13) (HCV NS5A-transactivated protein 13) (Nucleolar 130 kDa protein) (Nucleolar phosphoprotein p130) NOLC1 KIAA0035 NS5ATP13 Homo sapiens (Human) box H/ACA RNA metabolic process [GO:0033979]; mitotic cell cycle [GO:0000278]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; nucleolus organization [GO:0007000]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of protein import into nucleus [GO:0042306]; regulation of translation [GO:0006417]; response to osmotic stress [GO:0006970]; rRNA processing [GO:0006364] box C/D RNP complex [GO:0031428]; box H/ACA snoRNP complex [GO:0031429]; Cajal body [GO:0015030]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] ATP binding [GO:0005524]; box C/D RNA binding [GO:0034512]; box C/D snoRNP complex binding [GO:0062064]; box H/ACA snoRNA binding [GO:0034513]; box H/ACA snoRNP complex binding [GO:0062065]; GTP binding [GO:0005525]; molecular function inhibitor activity [GO:0140678]; nuclear localization sequence binding [GO:0008139]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; protein-macromolecule adaptor activity [GO:0030674]; RNA binding [GO:0003723]; TFIIB-class transcription factor binding [GO:0001093] 0.91753 -0.85885 ANGTSALTAQNGK 0 0 8.98319 0 0 0 0 0 9.87007 0 0 0 0 0 0 0 0 0 0 0 0 9.89532 0 9.74972 15.2435 15.1176 0 Q14980 NUMA1_HUMAN Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen) NUMA1 NMP22 NUMA Homo sapiens (Human) anastral spindle assembly [GO:0055048]; astral microtubule organization [GO:0030953]; cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; meiotic cell cycle [GO:0051321]; microtubule bundle formation [GO:0001578]; nucleus organization [GO:0006997]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of chromosome segregation [GO:0051984]; positive regulation of chromosome separation [GO:1905820]; positive regulation of hair follicle development [GO:0051798]; positive regulation of intracellular transport [GO:0032388]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of mitotic spindle elongation [GO:1902846]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of protein localization to spindle pole body [GO:1902365]; positive regulation of spindle assembly [GO:1905832]; regulation of metaphase plate congression [GO:0090235]; regulation of mitotic spindle organization [GO:0060236] cell cortex [GO:0005938]; cell cortex region [GO:0099738]; centrosome [GO:0005813]; chromosome [GO:0005694]; cortical microtubule [GO:0055028]; cytoplasmic microtubule bundle [GO:1905720]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extrinsic component of plasma membrane [GO:0019897]; lateral cell cortex [GO:0097575]; lateral plasma membrane [GO:0016328]; microtubule bundle [GO:0097427]; microtubule minus-end [GO:0036449]; microtubule plus-end [GO:0035371]; mitotic spindle [GO:0072686]; mitotic spindle astral microtubule [GO:0061673]; mitotic spindle midzone [GO:1990023]; mitotic spindle pole [GO:0097431]; neuronal cell body [GO:0043025]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle [GO:0005819]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; spindle pole centrosome [GO:0031616] disordered domain specific binding [GO:0097718]; dynein complex binding [GO:0070840]; microtubule binding [GO:0008017]; microtubule minus-end binding [GO:0051011]; microtubule plus-end binding [GO:0051010]; phosphatidylinositol binding [GO:0035091]; protein domain specific binding [GO:0019904]; protein-containing complex binding [GO:0044877]; structural molecule activity [GO:0005198]; tubulin binding [GO:0015631] 0.9686 -9.9662 ELEELRDK 0 0 0 0 0 0 8.95428 11.2786 0 10.673 10.5981 0 9.50539 0 8.79074 10.371 10.781 0 8.59474 10.9977 0 9.59783 0 9.37795 0 11.4323 0 Q14993 COJA1_HUMAN Collagen alpha-1(XIX) chain (Collagen alpha-1(Y) chain) COL19A1 Homo sapiens (Human) cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cell-cell adhesion [GO:0098609]; extracellular matrix organization [GO:0030198]; skeletal muscle tissue development [GO:0007519]; skeletal system development [GO:0001501] collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] extracellular matrix structural constituent [GO:0005201]; protein-macromolecule adaptor activity [GO:0030674] 0.9601 -1.9431 DKTEESCPILR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.07911 0 Q14994 NR1I3_HUMAN Nuclear receptor subfamily 1 group I member 3 (Constitutive activator of retinoid response) (Constitutive active response) (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67) NR1I3 CAR Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; positive regulation of transcription by RNA polymerase II [GO:0045944]; signal transduction [GO:0007165] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; nuclear receptor activity [GO:0004879]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]; zinc ion binding [GO:0008270]" 0.94707 -1.3526 QAQRRAQQTPVQLSK 0 0 0 0 0 0 0 0 0 0 11.8623 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14997 PSME4_HUMAN Proteasome activator complex subunit 4 (Proteasome activator PA200) PSME4 KIAA0077 Homo sapiens (Human) DNA damage response [GO:0006974]; DNA repair [GO:0006281]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; sperm DNA condensation [GO:0035092] cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spermatoproteasome complex [GO:1990111] lysine-acetylated histone binding [GO:0070577]; peptidase activator activity [GO:0016504]; proteasome binding [GO:0070628] 0.869 0.045325 LSTSSYSQVR 0 0 0 0 0 0 0 0 0 0 0 10.5103 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q14999 CUL7_HUMAN Cullin-7 (CUL-7) CUL7 KIAA0076 Homo sapiens (Human) epithelial to mesenchymal transition [GO:0001837]; Golgi organization [GO:0007030]; microtubule cytoskeleton organization [GO:0000226]; mitotic cytokinesis [GO:0000281]; placenta development [GO:0001890]; positive regulation of dendrite morphogenesis [GO:0050775]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of mitotic nuclear division [GO:0007088]; ubiquitin-dependent protein catabolic process [GO:0006511]; vasculogenesis [GO:0001570] 3M complex [GO:1990393]; anaphase-promoting complex [GO:0005680]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; perinuclear region of cytoplasm [GO:0048471] ubiquitin protein ligase binding [GO:0031625] 0.96958 -5.5142 EPRSRWDIVR 0 0 0 0 0 0 0 0 0 0 0 0 8.90038 9.26409 0 0 0 0 0 0 0 0 9.95042 0 0 0 0 Q149M9 NWD1_HUMAN NACHT domain- and WD repeat-containing protein 1 NWD1 Homo sapiens (Human) negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of gene expression [GO:0010628] cytosol [GO:0005829]; nucleolus [GO:0005730] ATP binding [GO:0005524] 0.96401 -2.1037 AINCMSLSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.56362 0 0 0 9.13853 0 0 0 Q149N8 SHPRH_HUMAN "E3 ubiquitin-protein ligase SHPRH (EC 2.3.2.27) (EC 3.6.4.-) (RING-type E3 ubiquitin transferase SHPRH) (SNF2, histone-linker, PHD and RING finger domain-containing helicase)" SHPRH KIAA2023 Homo sapiens (Human) DNA damage response [GO:0006974]; DNA repair [GO:0006281]; nucleosome assembly [GO:0006334]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567] nucleoplasm [GO:0005654]; nucleosome [GO:0000786] ATP binding [GO:0005524]; ATP-dependent chromatin remodeler activity [GO:0140658]; DNA binding [GO:0003677]; helicase activity [GO:0004386]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842] 0.9403 -1.3307 AVATSQLQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.99704 0 0 0 0 0 0 0 0 Q14BN4 SLMAP_HUMAN Sarcolemmal membrane-associated protein (Sarcolemmal-associated protein) SLMAP KIAA1601 SLAP UNQ1847/PRO3577 Homo sapiens (Human) muscle contraction [GO:0006936]; protein localization to plasma membrane [GO:0072659]; regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900825]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of voltage-gated sodium channel activity [GO:1905150] microtubule organizing center [GO:0005815]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; smooth endoplasmic reticulum [GO:0005790] 0.69348 0.38202 CQQCEDQQR 0 10.3872 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.0989 0 0 Q14C86 GAPD1_HUMAN GTPase-activating protein and VPS9 domain-containing protein 1 (GAPex-5) (Rab5-activating protein 6) GAPVD1 GAPEX5 KIAA1521 RAP6 Homo sapiens (Human) endocytosis [GO:0006897]; regulation of GTPase activity [GO:0043087]; regulation of protein transport [GO:0051223] cytosol [GO:0005829]; endocytic vesicle [GO:0030139]; endosome [GO:0005768]; plasma membrane [GO:0005886] cadherin binding [GO:0045296]; GTPase activating protein binding [GO:0032794]; GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; small GTPase binding [GO:0031267] 0.96373 -2.1321 FSPSQQEKLFGEK 9.81506 0 8.70605 0 0 0 0 0 8.68046 0 0 9.14812 8.93487 9.41229 0 0 0 0 0 0 0 0 0 0 0 0 8.40067 Q14CM0 FRPD4_HUMAN FERM and PDZ domain-containing protein 4 (PDZ domain-containing protein 10) (PSD-95-interacting regulator of spine morphogenesis) (Preso) FRMPD4 KIAA0316 PDZD10 PDZK10 Homo sapiens (Human) positive regulation of synapse structural plasticity [GO:0051835] cytoskeleton [GO:0005856]; dendritic spine [GO:0043197]; protein-containing complex [GO:0032991] "phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]" 0.92142 -1.1146 LSALQAK 0 0 14.1074 0 14.0401 0 9.07243 9.45937 9.453 10.132 10.542 10.6589 8.69077 8.73081 8.85406 9.18933 11.6014 9.42624 8.99969 8.10722 8.57992 0 0 8.88096 9.57164 9.71106 9.47861 Q14CN2 CLCA4_HUMAN "Calcium-activated chloride channel regulator 4 (EC 3.4.-.-) (Calcium-activated chloride channel family member 4) (hCLCA4) (Calcium-activated chloride channel protein 2) (CaCC-2) (hCaCC-2) (Chloride channel accessory 4) [Cleaved into: Calcium-activated chloride channel regulator 4, 110 kDa form; Calcium-activated chloride channel regulator 4, 30 kDa form]" CLCA4 CaCC2 UNQ562/PRO1124 Homo sapiens (Human) monoatomic ion transmembrane transport [GO:0034220]; proteolysis [GO:0006508] apical plasma membrane [GO:0016324]; extracellular region [GO:0005576]; plasma membrane [GO:0005886] chloride channel activity [GO:0005254]; intracellular calcium activated chloride channel activity [GO:0005229]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222] 0.92312 -1.1503 IEATRCSAGISGRNR 10.2219 10.256 10.2232 0 0 0 10.8496 10.198 10.1466 10.6231 0 10.4867 0 0 0 8.475 10.3692 10.2759 8.75211 9.14295 8.31075 10.1218 0 9.8083 10.2013 9.65338 9.54992 Q14CN4 K2C72_HUMAN "Keratin, type II cytoskeletal 72 (Cytokeratin-72) (CK-72) (Keratin-72) (K72) (Type II inner root sheath-specific keratin-K6irs2) (Type-II keratin Kb35)" KRT72 K6IRS2 KB35 KRT6 KRT6IRS2 Homo sapiens (Human) keratinization [GO:0031424] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; keratin filament [GO:0045095] structural constituent of skin epidermis [GO:0030280] 0.77141 0.27482 DLDLDSIIAEVR 0 0 10.09 0 0 0 0 10.9518 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.98502 0 0 0 Q14CZ7 FAKD3_HUMAN "FAST kinase domain-containing protein 3, mitochondrial" FASTKD3 Homo sapiens (Human) mitochondrial cytochrome c oxidase assembly [GO:0033617]; mitochondrial RNA processing [GO:0000963]; positive regulation of mitochondrial translation [GO:0070131]; regulation of mitochondrial mRNA stability [GO:0044528] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ribonucleoprotein granule [GO:0035770] RNA binding [GO:0003723] 0.89831 -0.65198 LDEEGFVLPSTANEDIHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9259 0 0 Q14CZ8 HECAM_HUMAN Hepatic and glial cell adhesion molecule (glialCAM) (Hepatocyte cell adhesion molecule) (Protein hepaCAM) HEPACAM Homo sapiens (Human) cell adhesion [GO:0007155]; cell cycle [GO:0007049]; protein localization [GO:0008104]; regulation of cell cycle [GO:0051726] axon [GO:0030424]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; membrane [GO:0016020] 0.67005 0.39399 APSSPGR 0 0 0 0 0 0 0 9.0649 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15003 CND2_HUMAN Condensin complex subunit 2 (Barren homolog protein 1) (Chromosome-associated protein H) (hCAP-H) (Non-SMC condensin I complex subunit H) (XCAP-H homolog) NCAPH BRRN BRRN1 CAPH KIAA0074 Homo sapiens (Human) cell division [GO:0051301]; female meiosis chromosome separation [GO:0051309]; meiotic chromosome condensation [GO:0010032]; mitotic chromosome condensation [GO:0007076]; positive regulation of chromosome condensation [GO:1905821]; positive regulation of chromosome segregation [GO:0051984]; positive regulation of chromosome separation [GO:1905820] condensed nuclear chromosome [GO:0000794]; condensin complex [GO:0000796]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654] chromatin binding [GO:0003682] 0.56427 0.51154 VAAGTLDASTK 0 0 0 0 0 0 10.0275 0 0 0 0 10.6546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15006 EMC2_HUMAN ER membrane protein complex subunit 2 (Tetratricopeptide repeat protein 35) (TPR repeat protein 35) EMC2 KIAA0103 TTC35 Homo sapiens (Human) protein insertion into ER membrane by stop-transfer membrane-anchor sequence [GO:0045050]; tail-anchored membrane protein insertion into ER membrane [GO:0071816] cytoplasm [GO:0005737]; EMC complex [GO:0072546]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extrinsic component of endoplasmic reticulum membrane [GO:0042406] 0.5921 0.44926 DNMKYASWAASQINR 13.7947 13.8101 13.3894 14.0099 14.0483 13.8293 13.48 13.5713 0 0 0 0 0 0 0 0 13.7423 12.2183 0 0 0 0 0 0 0 0 8.89014 Q15008 PSMD6_HUMAN 26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit RPN7) (26S proteasome regulatory subunit S10) (Breast cancer-associated protein SGA-113M) (Phosphonoformate immuno-associated protein 4) (Proteasome regulatory particle subunit p44S10) (p42A) PSMD6 KIAA0107 PFAAP4 Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; proteasome accessory complex [GO:0022624]; proteasome complex [GO:0000502]; proteasome regulatory particle [GO:0005838]; secretory granule lumen [GO:0034774] 0.87402 0.035363 SLDWQIDVDLLNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.69928 0 0 0 0 0 Q15013 MD2BP_HUMAN MAD2L1-binding protein (Caught by MAD2 protein) (p31(comet)) MAD2L1BP CMT2 KIAA0110 Homo sapiens (Human) deactivation of mitotic spindle assembly checkpoint [GO:1902426]; regulation of exit from mitosis [GO:0007096] cytoplasm [GO:0005737]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819] 0.88238 -0.071012 AAPEAEVLSSAAVPDLEWYEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.66479 0 0 0 Q15019 SEPT2_HUMAN Septin-2 (Neural precursor cell expressed developmentally down-regulated protein 5) (NEDD-5) SEPTIN2 DIFF6 KIAA0158 NEDD5 SEPT2 Homo sapiens (Human) cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; cytoskeleton-dependent cytokinesis [GO:0061640]; regulation of exocytosis [GO:0017157]; smoothened signaling pathway [GO:0007224]; spermatogenesis [GO:0007283] actin cytoskeleton [GO:0015629]; axoneme [GO:0005930]; cell division site [GO:0032153]; ciliary membrane [GO:0060170]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; kinetochore [GO:0000776]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; non-motile cilium [GO:0097730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; photoreceptor connecting cilium [GO:0032391]; plasma membrane [GO:0005886]; septin complex [GO:0031105]; septin ring [GO:0005940]; sperm annulus [GO:0097227]; spindle [GO:0005819]; synaptic vesicle [GO:0008021] cadherin binding [GO:0045296]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; molecular adaptor activity [GO:0060090] 0.61293 0.42567 ASIPFSVVGSNQLIEAK 0 0 0 0 0 0 0 0 0 10.7725 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15020 SART3_HUMAN Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3) (Tat-interacting protein of 110 kDa) (Tip110) (p110 nuclear RNA-binding protein) SART3 KIAA0156 TIP110 Homo sapiens (Human) "cell morphogenesis [GO:0000902]; hematopoietic stem cell proliferation [GO:0071425]; homeostasis of number of cells [GO:0048872]; mRNA splicing, via spliceosome [GO:0000398]; nucleosome assembly [GO:0006334]; regulation of gene expression [GO:0010468]; spliceosomal snRNP assembly [GO:0000387]; spliceosomal tri-snRNP complex assembly [GO:0000244]; transcription elongation-coupled chromatin remodeling [GO:0140673]" ASAP complex [GO:0061574]; Cajal body [GO:0015030]; cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] deubiquitinase activator activity [GO:0035800]; histone binding [GO:0042393]; RNA binding [GO:0003723]; U4 snRNA binding [GO:0030621]; U6 snRNA binding [GO:0017070]; U6atac snRNA binding [GO:0030624]; ubiquitin-specific protease binding [GO:1990381] 0.76037 0.29475 EELEEICK 0 0 0 0 0 0 0 11.8839 0 0 0 10.129 0 0 0 9.06242 0 9.16513 0 0 0 0 0 0 0 0 0 Q15021 CND1_HUMAN Condensin complex subunit 1 (Chromosome condensation-related SMC-associated protein 1) (Chromosome-associated protein D2) (hCAP-D2) (Non-SMC condensin I complex subunit D2) (XCAP-D2 homolog) NCAPD2 CAPD2 CNAP1 KIAA0159 Homo sapiens (Human) cell division [GO:0051301]; meiotic chromosome condensation [GO:0010032]; mitotic chromosome condensation [GO:0007076]; positive regulation of chromosome condensation [GO:1905821]; positive regulation of chromosome segregation [GO:0051984]; positive regulation of chromosome separation [GO:1905820] "condensed chromosome [GO:0000793]; condensed chromosome, centromeric region [GO:0000779]; condensed nuclear chromosome [GO:0000794]; condensin complex [GO:0000796]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]" histone binding [GO:0042393] 0.96954 -4.0937 CSSVMLLGMMAR 0 0 0 0 0 0 0 0 0 0 9.80478 0 0 0 0 0 0 0 0 0 0 8.04139 0 0 0 10.6456 0 Q15024 EXOS7_HUMAN Exosome complex component RRP42 (Exosome component 7) (Ribosomal RNA-processing protein 42) (p8) EXOSC7 KIAA0116 RRP42 Homo sapiens (Human) "exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; rRNA processing [GO:0006364]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476]" cytoplasmic exosome (RNase complex) [GO:0000177]; cytosol [GO:0005829]; exosome (RNase complex) [GO:0000178]; nuclear exosome (RNase complex) [GO:0000176]; nucleolar exosome (RNase complex) [GO:0101019]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 3'-5'-RNA exonuclease activity [GO:0000175]; RNA binding [GO:0003723] 0.3655 0.74394 GGDDLGTEIANTLYRIFNNK 11.6943 0 0 14.4031 14.6698 10.194 0 0 0 0 14.423 0 11.5624 0 0 0 0 0 11.2285 0 0 0 10.3467 0 0 0 0 Q15025 TNIP1_HUMAN TNFAIP3-interacting protein 1 (A20-binding inhibitor of NF-kappa-B activation 1) (ABIN-1) (HIV-1 Nef-interacting protein) (Nef-associated factor 1) (Naf1) (Nip40-1) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) TNIP1 KIAA0113 NAF1 Homo sapiens (Human) cellular response to lipopolysaccharide [GO:0071222]; defense response [GO:0006952]; glycoprotein biosynthetic process [GO:0009101]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of viral genome replication [GO:0045071]; positive regulation of inflammatory response [GO:0050729]; positive regulation of protein deubiquitination [GO:1903003]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; translation [GO:0006412] cytosol [GO:0005829]; nucleoplasm [GO:0005654] identical protein binding [GO:0042802]; mitogen-activated protein kinase binding [GO:0051019] 0.94051 -1.3173 LFHLPEYTWR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7652 0 0 0 0 0 0 0 0 0 0 9.74749 Q15027 ACAP1_HUMAN "Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 (Centaurin-beta-1) (Cnt-b1)" ACAP1 CENTB1 KIAA0050 Homo sapiens (Human) protein transport [GO:0015031] membrane [GO:0016020]; recycling endosome membrane [GO:0055038] GTPase activator activity [GO:0005096]; metal ion binding [GO:0046872] 0.96801 -2.9234 GGRGRPR 0 8.67186 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.83521 0 0 0 0 0 0 0 0 Q15029 U5S1_HUMAN "116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (SNU114 homolog) (hSNU114) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa)" EFTUD2 KIAA0031 SNRP116 Homo sapiens (Human) "cellular response to xenobiotic stimulus [GO:0071466]; mRNA splicing, via spliceosome [GO:0000398]; response to cocaine [GO:0042220]" Cajal body [GO:0015030]; catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; RNA binding [GO:0003723]; U5 snRNA binding [GO:0030623] 0.50774 0.60722 EGPLCDELIR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8719 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15031 SYLM_HUMAN "Leucine--tRNA ligase, mitochondrial (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)" LARS2 KIAA0028 Homo sapiens (Human) leucyl-tRNA aminoacylation [GO:0006429]; mitochondrial translation [GO:0032543]; tRNA aminoacylation for protein translation [GO:0006418] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; leucine-tRNA ligase activity [GO:0004823] 0.96499 -2.3782 DWLISRQR 11.7452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15034 HERC3_HUMAN Probable E3 ubiquitin-protein ligase HERC3 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 3) (HECT-type E3 ubiquitin transferase HERC3) HERC3 KIAA0032 Homo sapiens (Human) protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410] ubiquitin protein ligase activity [GO:0061630] 0.88541 -0.38513 GQLGHER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.64744 0 0 0 0 0 0 Q15036 SNX17_HUMAN Sorting nexin-17 SNX17 KIAA0064 Homo sapiens (Human) aorta development [GO:0035904]; cardiac septum development [GO:0003279]; cholesterol catabolic process [GO:0006707]; coronary vasculature development [GO:0060976]; endocytic recycling [GO:0032456]; endosomal transport [GO:0016197]; intracellular protein transport [GO:0006886]; kidney development [GO:0001822]; receptor-mediated endocytosis [GO:0006898]; regulation of endocytosis [GO:0030100]; signal transduction [GO:0007165] cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; protein-containing complex [GO:0032991] low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol binding [GO:0035091]; signaling receptor binding [GO:0005102] 0.89052 -0.48156 ESMVKLSSK 0 0 0 0 0 0 0 9.90185 0 0 9.70409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.33546 0 Q15042 RB3GP_HUMAN Rab3 GTPase-activating protein catalytic subunit (RAB3 GTPase-activating protein 130 kDa subunit) (Rab3-GAP p130) (Rab3-GAP) RAB3GAP1 KIAA0066 RAB3GAP Homo sapiens (Human) brain development [GO:0007420]; camera-type eye development [GO:0043010]; establishment of protein localization to endoplasmic reticulum membrane [GO:0097051]; excitatory postsynaptic potential [GO:0060079]; face morphogenesis [GO:0060325]; hypothalamus development [GO:0021854]; lipid droplet organization [GO:0034389]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of endoplasmic reticulum tubular network organization [GO:1903373]; positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization [GO:0061646]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein lipidation [GO:1903061]; regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903233]; regulation of GTPase activity [GO:0043087]; regulation of short-term neuronal synaptic plasticity [GO:0048172] cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum tubular network [GO:0071782]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; lipid droplet [GO:0005811]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991] GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; small GTPase binding [GO:0031267] 0.93105 -1.2498 AGDQLVPDNLKETDK 13.353 0 14.1948 0 0 0 0 0 0 0 0 10.9384 0 0 0 0 0 0 10.8584 0 0 9.61695 0 0 0 0 0 Q15046 SYK_HUMAN Lysine--tRNA ligase (EC 2.7.7.-) (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS) KARS1 KARS KIAA0070 Homo sapiens (Human) basophil activation involved in immune response [GO:0002276]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; ERK1 and ERK2 cascade [GO:0070371]; lysyl-tRNA aminoacylation [GO:0006430]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of inflammatory response to antigenic stimulus [GO:0002863]; positive regulation of macrophage activation [GO:0043032]; response to X-ray [GO:0010165]; tRNA processing [GO:0008033] aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886] amino acid binding [GO:0016597]; ATP adenylyltransferase activity [GO:0003877]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; lysine-tRNA ligase activity [GO:0004824]; protein homodimerization activity [GO:0042803]; tRNA binding [GO:0000049] 0.96759 -2.9861 AVECPPPR 0 0 0 0 0 10.3144 0 0 0 0 11.4751 0 12.3812 0 0 9.94037 0 0 9.80537 0 10.7884 0 0 9.24236 0 0 8.23112 Q15047 SETB1_HUMAN Histone-lysine N-methyltransferase SETDB1 (EC 2.1.1.366) (ERG-associated protein with SET domain) (ESET) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (Lysine N-methyltransferase 1E) (SET domain bifurcated 1) SETDB1 ESET KIAA0067 KMT1E Homo sapiens (Human) heterochromatin organization [GO:0070828]; histone H3-K9 methylation [GO:0051567]; negative regulation of gene expression [GO:0010629]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309] chromosome [GO:0005694]; cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; histone H3K9 methyltransferase activity [GO:0046974]; histone H3K9 monomethyltransferase activity [GO:0140948]; histone H3K9 trimethyltransferase activity [GO:0140949]; histone H3K9me2 methyltransferase activity [GO:0140947]; promoter-specific chromatin binding [GO:1990841]; zinc ion binding [GO:0008270] 0.96695 -2.8343 AGGSRMEAEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.4023 0 Q15048 LRC14_HUMAN Leucine-rich repeat-containing protein 14 LRRC14 KIAA0014 Homo sapiens (Human) negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of toll-like receptor signaling pathway [GO:0034122] cytoplasm [GO:0005737]; cytosol [GO:0005829] kinase binding [GO:0019900] 0.84935 0.1202 ELLRDSVAQAELR 0 0 0 0 0 0 0 0 0 9.0126 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15050 RRS1_HUMAN Ribosome biogenesis regulatory protein homolog RRS1 KIAA0112 RRR Homo sapiens (Human) "endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; hematopoietic progenitor cell differentiation [GO:0002244]; mitotic metaphase plate congression [GO:0007080]; protein localization to nucleolus [GO:1902570]; regulation of signal transduction by p53 class mediator [GO:1901796]; ribosomal large subunit assembly [GO:0000027]; ribosomal large subunit biogenesis [GO:0042273]" "condensed nuclear chromosome [GO:0000794]; endoplasmic reticulum [GO:0005783]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; preribosome, large subunit precursor [GO:0030687]" 5S rRNA binding [GO:0008097]; RNA binding [GO:0003723] 0.93288 -1.2853 GGRQGPGGKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.91437 0 0 0 0 0 0 0 0 Q15051 IQCB1_HUMAN IQ calmodulin-binding motif-containing protein 1 (Nephrocystin-5) (p53 and DNA damage-regulated IQ motif protein) (PIQ) IQCB1 KIAA0036 NPHP5 OK/SW-cl.85 Homo sapiens (Human) cilium assembly [GO:0060271]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494] centriole [GO:0005814]; centrosome [GO:0005813]; cilium [GO:0005929]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; microtubule cytoskeleton [GO:0015630]; mitotic spindle [GO:0072686]; nucleoplasm [GO:0005654]; photoreceptor connecting cilium [GO:0032391]; photoreceptor outer segment [GO:0001750] calmodulin binding [GO:0005516]; enzyme binding [GO:0019899] 0.97016 -5.3546 AALKFLAKCR 8.8205 0 0 0 0 0 0 0 8.54794 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15052 ARHG6_HUMAN Rho guanine nucleotide exchange factor 6 (Alpha-Pix) (COOL-2) (PAK-interacting exchange factor alpha) (Rac/Cdc42 guanine nucleotide exchange factor 6) ARHGEF6 COOL2 KIAA0006 PIXA Homo sapiens (Human) apoptotic process [GO:0006915]; JNK cascade [GO:0007254]; lamellipodium assembly [GO:0030032] cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lamellipodium [GO:0030027] GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085] 0.93034 -1.239 MKQCLEEELK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.40969 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15054 DPOD3_HUMAN DNA polymerase delta subunit 3 (DNA polymerase delta subunit C) (DNA polymerase delta subunit p66) (DNA polymerase delta subunit p68) POLD3 KIAA0039 Homo sapiens (Human) "DNA biosynthetic process [GO:0071897]; DNA strand elongation involved in DNA replication [GO:0006271]; DNA synthesis involved in DNA repair [GO:0000731]; DNA synthesis involved in UV-damage excision repair [GO:1904161]; DNA-templated DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; mismatch repair [GO:0006298]; nucleotide-excision repair, DNA gap filling [GO:0006297]" cytoplasm [GO:0005737]; delta DNA polymerase complex [GO:0043625]; nucleoplasm [GO:0005654]; zeta DNA polymerase complex [GO:0016035] protein-macromolecule adaptor activity [GO:0030674] 0.96968 -4.6692 EPREERK 0 0 0 0 0 0 0 0 9.88646 0 0 11.2242 0 0 0 0 0 10.2893 0 0 0 0 0 0 0 0 0 Q15056 IF4H_HUMAN Eukaryotic translation initiation factor 4H (eIF-4H) (Williams-Beuren syndrome chromosomal region 1 protein) EIF4H KIAA0038 WBSCR1 WSCR1 Homo sapiens (Human) developmental growth [GO:0048589]; regulation of translational initiation [GO:0006446]; sexual reproduction [GO:0019953] cytosol [GO:0005829]; eukaryotic translation initiation factor 4F complex [GO:0016281]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; polysome [GO:0005844] "cadherin binding [GO:0045296]; RNA binding [GO:0003723]; translation factor activity, RNA binding [GO:0008135]; translation initiation factor activity [GO:0003743]" 0 3.9637 ADFDTYDDR 9.27975 0 0 0 0 0 0 0 0 0 0 0 9.95251 9.70119 9.85487 9.5263 10.1933 0 9.4874 9.29439 0 0 0 0 0 9.92679 10.4325 Q15057 ACAP2_HUMAN "Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 (Centaurin-beta-2) (Cnt-b2)" ACAP2 CENTB2 KIAA0041 Homo sapiens (Human) actin filament-based process [GO:0030029]; cellular response to nerve growth factor stimulus [GO:1990090]; endocytic recycling [GO:0032456] endosome membrane [GO:0010008]; membrane [GO:0016020]; ruffle [GO:0001726] GTPase activator activity [GO:0005096]; metal ion binding [GO:0046872] 0.92254 -1.0828 FVSKSSEEK 0 0 0 0 11.6247 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.25941 0 8.14119 0 0 0 0 0 Q15058 KIF14_HUMAN Kinesin-like protein KIF14 KIF14 KIAA0042 Homo sapiens (Human) activation of protein kinase activity [GO:0032147]; cell division [GO:0051301]; cell proliferation in forebrain [GO:0021846]; cerebellar cortex development [GO:0021695]; cerebellar granular layer structural organization [GO:0021685]; cerebellar Purkinje cell layer structural organization [GO:0021693]; cerebral cortex development [GO:0021987]; establishment of protein localization [GO:0045184]; hippocampus development [GO:0021766]; microtubule-based movement [GO:0007018]; mitotic metaphase plate congression [GO:0007080]; negative regulation of apoptotic process [GO:0043066]; negative regulation of integrin activation [GO:0033624]; negative regulation of neuron apoptotic process [GO:0043524]; olfactory bulb development [GO:0021772]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of cell growth [GO:0001558]; regulation of cell maturation [GO:1903429]; regulation of cell migration [GO:0030334]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of myelination [GO:0031641]; regulation of neuron apoptotic process [GO:0043523]; regulation of Rap protein signal transduction [GO:0032487]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; substrate adhesion-dependent cell spreading [GO:0034446] cytosol [GO:0005829]; Flemming body [GO:0090543]; kinesin complex [GO:0005871]; membrane [GO:0016020]; microtubule [GO:0005874]; midbody [GO:0030496]; nucleus [GO:0005634]; spindle midzone [GO:0051233] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777]; PDZ domain binding [GO:0030165]; plus-end-directed microtubule motor activity [GO:0008574]; protein kinase binding [GO:0019901]; tubulin binding [GO:0015631] 0.97 -4.3271 DMAEMQRVWK 13.2311 0 0 0 0 0 0 10.7124 0 10.007 0 0 10.9754 0 0 0 0 0 10.1288 0 0 0 0 9.82799 0 12.3351 10.9077 Q15059 BRD3_HUMAN Bromodomain-containing protein 3 (RING3-like protein) BRD3 KIAA0043 RING3L Homo sapiens (Human) chromatin organization [GO:0006325]; regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577] 0.96989 -4.4079 AKVAPPAKQAQQK 0 0 0 0 0 0 9.69801 0 0 0 0 0 0 9.89292 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15063 POSTN_HUMAN Periostin (PN) (Osteoblast-specific factor 2) (OSF-2) POSTN OSF2 Homo sapiens (Human) cell adhesion [GO:0007155]; cellular response to vitamin K [GO:0071307]; extracellular matrix organization [GO:0030198]; regulation of Notch signaling pathway [GO:0008593]; tissue development [GO:0009888] collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; trans-Golgi network [GO:0005802] cell adhesion molecule binding [GO:0050839]; heparin binding [GO:0008201]; metal ion binding [GO:0046872] 0.88453 -0.21172 EIIKPAEK 0 0 0 0 0 9.44933 9.15249 0 0 0 0 0 0 0 0 9.23867 9.2097 9.27705 0 0 0 0 0 0 9.0785 0 9.0847 Q15067 ACOX1_HUMAN "Peroxisomal acyl-coenzyme A oxidase 1 (AOX) (EC 1.3.3.6) (Palmitoyl-CoA oxidase) (Peroxisomal fatty acyl-CoA oxidase) (Straight-chain acyl-CoA oxidase) (SCOX) [Cleaved into: Peroxisomal acyl-CoA oxidase 1, A chain; Peroxisomal acyl-CoA oxidase 1, B chain; Peroxisomal acyl-CoA oxidase 1, C chain]" ACOX1 ACOX Homo sapiens (Human) cholesterol homeostasis [GO:0042632]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; fatty acid catabolic process [GO:0009062]; fatty acid oxidation [GO:0019395]; generation of precursor metabolites and energy [GO:0006091]; hydrogen peroxide biosynthetic process [GO:0050665]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; peroxisome fission [GO:0016559]; prostaglandin metabolic process [GO:0006693]; spermatogenesis [GO:0007283]; very long-chain fatty acid beta-oxidation [GO:0140493]; very long-chain fatty acid metabolic process [GO:0000038] cytosol [GO:0005829]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777] acyl-CoA oxidase activity [GO:0003997]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]; palmitoyl-CoA oxidase activity [GO:0016401]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803] 0.95185 -1.3907 AEVHESYKHLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.367 0 9.94297 0 0 0 0 10.477 0 0 0 0 Q15070 OXA1L_HUMAN Mitochondrial inner membrane protein OXA1L (Hsa) (OXA1Hs) (Oxidase assembly 1-like protein) (OXA1-like protein) OXA1L Homo sapiens (Human) aerobic respiration [GO:0009060]; mitochondrial proton-transporting ATP synthase complex assembly [GO:0033615]; mitochondrial respiratory chain complex I assembly [GO:0032981]; negative regulation of ATP-dependent activity [GO:0032780]; negative regulation of oxidoreductase activity [GO:0051354]; protein insertion into mitochondrial inner membrane from matrix [GO:0032979]; protein tetramerization [GO:0051262] mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991] membrane insertase activity [GO:0032977]; mitochondrial ribosome binding [GO:0097177]; protein homodimerization activity [GO:0042803] 0.96937 -4.5722 AMGLMCGRR 0 0 0 0 10.8988 8.99966 0 10.0309 0 0 0 0 0 10.5475 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15075 EEA1_HUMAN Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2) EEA1 ZFYVE2 Homo sapiens (Human) "chemical synaptic transmission, postsynaptic [GO:0099565]; early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; modulation by host of viral process [GO:0044788]; synaptic vesicle to endosome fusion [GO:0016189]; vesicle fusion [GO:0006906]" axonal spine [GO:0044308]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; extracellular exosome [GO:0070062]; extrinsic component of plasma membrane [GO:0019897]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; postsynapse [GO:0098794]; Schaffer collateral - CA1 synapse [GO:0098685]; serine-pyruvate aminotransferase complex [GO:0005969] 1-phosphatidylinositol binding [GO:0005545]; calmodulin binding [GO:0005516]; GTP-dependent protein binding [GO:0030742]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270] 0.96933 -5.6501 ADLQNHLDTAQNALQDK 0 0 11.2019 0 12.4747 0 0 0 0 12.0402 12.5312 0 10.6992 14.2088 0 9.22687 15.3003 0 13.3662 11.2393 12.7332 13.6239 11.1945 12.3652 11.0532 0 8.17313 Q15077 P2RY6_HUMAN P2Y purinoceptor 6 (P2Y6) P2RY6 PP2891 Homo sapiens (Human) "activation of phospholipase C activity [GO:0007202]; cellular response to prostaglandin E stimulus [GO:0071380]; cellular response to purine-containing compound [GO:0071415]; cellular response to pyrimidine ribonucleotide [GO:1905835]; G protein-coupled receptor signaling pathway [GO:0007186]; phagocytosis [GO:0006909]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; transepithelial chloride transport [GO:0030321]" apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; plasma membrane [GO:0005886] G protein-coupled ADP receptor activity [GO:0001621]; G protein-coupled receptor activity [GO:0004930]; G protein-coupled UDP receptor activity [GO:0045029]; G protein-coupled UTP receptor activity [GO:0045030] 0.96946 -4.8257 LTAKWQR 0 0 0 0 9.07465 0 0 0 0 10.5643 10.0523 10.0037 10.6371 0 8.43146 9.50078 0 0 0 0 0 0 0 0 0 9.83183 9.78211 Q15078 CD5R1_HUMAN "Cyclin-dependent kinase 5 activator 1 (CDK5 activator 1) (Cyclin-dependent kinase 5 regulatory subunit 1) (TPKII regulatory subunit) [Cleaved into: Cyclin-dependent kinase 5 activator 1, p35 (p35); Cyclin-dependent kinase 5 activator 1, p25 (p25) (Tau protein kinase II 23 kDa subunit) (p23)]" CDK5R1 CDK5R NCK5A Homo sapiens (Human) axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; brain development [GO:0007420]; cerebellum development [GO:0021549]; embryo development ending in birth or egg hatching [GO:0009792]; ephrin receptor signaling pathway [GO:0048013]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G1 to G0 transition involved in cell differentiation [GO:0070315]; hippocampus development [GO:0021766]; ionotropic glutamate receptor signaling pathway [GO:0035235]; layer formation in cerebral cortex [GO:0021819]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of DNA-templated transcription [GO:0045892]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of signaling receptor activity [GO:2000273]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of macroautophagy [GO:0016241]; regulation of neuron differentiation [GO:0045664]; regulation of synaptic vesicle cycle [GO:0098693]; rhythmic process [GO:0048511]; serine phosphorylation of STAT protein [GO:0042501]; superior olivary nucleus maturation [GO:0021722] axon [GO:0030424]; contractile fiber [GO:0043292]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; growth cone [GO:0030426]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; protein kinase 5 complex [GO:0016533] actin filament binding [GO:0051015]; alpha-tubulin binding [GO:0043014]; beta-tubulin binding [GO:0048487]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; ephrin receptor binding [GO:0046875]; ionotropic glutamate receptor binding [GO:0035255]; kinase activity [GO:0016301]; protease binding [GO:0002020]; protein kinase activator activity [GO:0030295]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activator activity [GO:0043539] 0.95901 -1.7646 IVAVSAKKK 9.80565 0 0 0 0 9.26181 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15084 PDIA6_HUMAN Protein disulfide-isomerase A6 (EC 5.3.4.1) (Endoplasmic reticulum protein 5) (ER protein 5) (ERp5) (Protein disulfide isomerase P5) (Thioredoxin domain-containing protein 7) PDIA6 ERP5 P5 TXNDC7 Homo sapiens (Human) protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; melanosome [GO:0042470]; plasma membrane [GO:0005886] protein disulfide isomerase activity [GO:0003756]; protein-disulfide reductase activity [GO:0015035] 0 167.71 DGELPVEDDIDLSDVELDDLGKDEL 11.1807 10.8359 10.393 0 9.1192 0 11.4645 11.6089 11.5126 9.67456 10.679 10.5749 11.2585 11.4353 12.3611 12.6673 12.7659 11.7106 12.4361 12.652 11.9069 11.5428 11.8595 12.3961 13.7364 13.2477 13.6757 Q15102 PA1B3_HUMAN Platelet-activating factor acetylhydrolase IB subunit alpha1 (EC 3.1.1.47) (PAF acetylhydrolase 29 kDa subunit) (PAF-AH 29 kDa subunit) (PAF-AH subunit gamma) (PAFAH subunit gamma) PAFAH1B3 PAFAHG Homo sapiens (Human) brain development [GO:0007420]; lipid catabolic process [GO:0016042]; lipid metabolic process [GO:0006629]; nervous system development [GO:0007399]; spermatogenesis [GO:0007283] 1-alkyl-2-acetylglycerophosphocholine esterase complex [GO:0008247]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020] 1-alkyl-2-acetylglycerophosphocholine esterase activity [GO:0003847]; identical protein binding [GO:0042802]; platelet-activating factor acetyltransferase activity [GO:0047179]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877] 0.0078329 2.0475 AIVQLVNERQPQAR 0 0 0 0 0 0 0 11.5815 14.3081 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.08303 0 10.7875 Q15116 PDCD1_HUMAN Programmed cell death protein 1 (Protein PD-1) (hPD-1) (CD antigen CD279) PDCD1 PD1 Homo sapiens (Human) adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; B cell apoptotic process [GO:0001783]; humoral immune response [GO:0006959]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of T cell apoptotic process [GO:0070234]; regulation of immune response [GO:0050776]; regulatory T cell apoptotic process [GO:1902482] external side of plasma membrane [GO:0009897]; plasma membrane [GO:0005886] 0.962 -2.5603 GSADGPR 0 0 0 0 0 0 8.43692 0 0 0 8.96573 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15119 PDK2_HUMAN "[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2) (PDH kinase 2) (PDKII)" PDK2 PDHK2 Homo sapiens (Human) cellular response to nutrient [GO:0031670]; cellular response to reactive oxygen species [GO:0034614]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; insulin receptor signaling pathway [GO:0008286]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; protein phosphorylation [GO:0006468]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cellular ketone metabolic process [GO:0010565]; regulation of gluconeogenesis [GO:0006111]; regulation of glucose metabolic process [GO:0010906]; regulation of pH [GO:0006885] cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrial pyruvate dehydrogenase complex [GO:0005967]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; pyruvate dehydrogenase (acetyl-transferring) kinase activity [GO:0004740] 0.91476 -0.83053 RWVWALLK 0 0 0 0 0 11.4922 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15120 PDK3_HUMAN "[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 3)" PDK3 PDHK3 Homo sapiens (Human) cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; glucose metabolic process [GO:0006006]; hypoxia-inducible factor-1alpha signaling pathway [GO:0097411]; peptidyl-serine phosphorylation [GO:0018105]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; protein phosphorylation [GO:0006468]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]; regulation of glucose metabolic process [GO:0010906]; regulation of reactive oxygen species metabolic process [GO:2000377] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730] ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; pyruvate dehydrogenase (acetyl-transferring) kinase activity [GO:0004740] 0.96861 -3.608 FGFDPFISTNIQYFLDRFYTNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0541 0 0 9.76759 0 0 0 0 0 0 Q15124 PGM5_HUMAN Phosphoglucomutase-like protein 5 (Aciculin) (Phosphoglucomutase-related protein) (PGM-RP) PGM5 PGMRP Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; cell adhesion [GO:0007155]; myofibril assembly [GO:0030239]; striated muscle tissue development [GO:0014706] adherens junction [GO:0005912]; cell-substrate junction [GO:0030055]; costamere [GO:0043034]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; dystrophin-associated glycoprotein complex [GO:0016010]; focal adhesion [GO:0005925]; intercalated disc [GO:0014704]; sarcolemma [GO:0042383]; spot adherens junction [GO:0005914]; stress fiber [GO:0001725]; Z disc [GO:0030018] "intramolecular transferase activity, phosphotransferases [GO:0016868]; magnesium ion binding [GO:0000287]; structural molecule activity [GO:0005198]" 0.95196 -1.3838 QEFDLENK 0 0 0 0 0 0 0 0 0 0 11.1534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15125 EBP_HUMAN "3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EC 5.3.3.5) (Cholestenol Delta-isomerase) (Delta(8)-Delta(7) sterol isomerase) (D8-D7 sterol isomerase) (Emopamil-binding protein)" EBP Homo sapiens (Human) cholesterol biosynthetic process [GO:0006695]; cholesterol biosynthetic process via desmosterol [GO:0033489]; cholesterol biosynthetic process via lathosterol [GO:0033490]; cholesterol metabolic process [GO:0008203]; hemopoiesis [GO:0030097]; ossification involved in bone maturation [GO:0043931] cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965] C-8 sterol isomerase activity [GO:0000247]; cholestenol delta-isomerase activity [GO:0047750]; identical protein binding [GO:0042802]; steroid delta-isomerase activity [GO:0004769] 0.69666 0.38027 AAVVPLGTWR 0 0 0 0 0 0 9.23079 0 0 9.06835 0 0 0 0 0 0 0 9.49689 0 0 0 0 0 0 0 0 9.19444 Q15126 PMVK_HUMAN Phosphomevalonate kinase (PMKase) (hPMK) (EC 2.7.4.2) PMVK PMKI Homo sapiens (Human) "cholesterol biosynthetic process [GO:0006695]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]; phosphorylation [GO:0016310]; response to cholesterol [GO:0070723]; sterol biosynthetic process [GO:0016126]" cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; peroxisome [GO:0005777] ATP binding [GO:0005524]; phosphomevalonate kinase activity [GO:0004631] 0.072835 1.2765 IVEGISQPIWLVSDTRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.58875 0 0 0 0 0 0 0 0 0 Q15139 KPCD1_HUMAN Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu) PRKD1 PKD PKD1 PRKCM Homo sapiens (Human) angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cellular response to amino acid starvation [GO:0034198]; cellular response to hydroperoxide [GO:0071447]; cellular response to oxidative stress [GO:0034599]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; defense response to Gram-negative bacterium [GO:0050829]; Golgi organization [GO:0007030]; Golgi vesicle transport [GO:0048193]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; negative regulation of endocytosis [GO:0045806]; nervous system development [GO:0007399]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of angiogenesis [GO:0045766]; positive regulation of autophagy [GO:0010508]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autophosphorylation [GO:0046777]; protein kinase D signaling [GO:0089700]; regulation of integrin-mediated signaling pathway [GO:2001044]; regulation of keratinocyte proliferation [GO:0010837]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; signal transduction [GO:0007165]; sphingolipid biosynthetic process [GO:0030148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] autophagosome membrane [GO:0000421]; cell cortex [GO:0005938]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802] ATP binding [GO:0005524]; calcium-dependent protein kinase C activity [GO:0004698]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein kinase C activity [GO:0004697]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.92664 -1.2145 ELECKIGER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.06296 9.3338 0 0 0 0 0 0 0 10.6818 0 0 Q15147 PLCB4_HUMAN "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4)" PLCB4 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; release of sequestered calcium ion into cytosol [GO:0051209] cytosol [GO:0005829] calcium ion binding [GO:0005509]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipase C activity [GO:0004629] 0.959 -1.9567 AISQDKSIK 14.375 0 0 0 0 0 0 0 0 0 0 0 0 0 9.92229 0 0 0 0 0 9.85094 0 0 0 0 0 0 Q15149 PLEC_HUMAN Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1) PLEC PLEC1 Homo sapiens (Human) actomyosin contractile ring assembly actin filament organization [GO:2000689]; adherens junction organization [GO:0034332]; cardiac muscle cell development [GO:0055013]; cell morphogenesis [GO:0000902]; cellular response to extracellular stimulus [GO:0031668]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrostatic pressure [GO:0071464]; cellular response to mechanical stimulus [GO:0071260]; establishment of skin barrier [GO:0061436]; fibroblast migration [GO:0010761]; gene expression [GO:0010467]; hemidesmosome assembly [GO:0031581]; intermediate filament cytoskeleton organization [GO:0045104]; intermediate filament organization [GO:0045109]; keratinocyte development [GO:0003334]; leukocyte migration involved in immune response [GO:0002522]; mitochondrion morphogenesis [GO:0070584]; multicellular organism growth [GO:0035264]; myoblast differentiation [GO:0045445]; negative regulation of protein kinase activity [GO:0006469]; nucleus organization [GO:0006997]; peripheral nervous system myelin maintenance [GO:0032287]; protein localization [GO:0008104]; protein-containing complex organization [GO:0043933]; regulation of ATP citrate synthase activity [GO:2000983]; regulation of vascular permeability [GO:0043114]; respiratory electron transport chain [GO:0022904]; response to food [GO:0032094]; sarcomere organization [GO:0045214]; skeletal muscle fiber development [GO:0048741]; skeletal myofibril assembly [GO:0014866]; T cell chemotaxis [GO:0010818]; tight junction organization [GO:0120193]; transmission of nerve impulse [GO:0019226]; wound healing [GO:0042060] axon [GO:0030424]; brush border [GO:0005903]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; hemidesmosome [GO:0030056]; intermediate filament cytoskeleton [GO:0045111]; mitochondrial outer membrane [GO:0005741]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; Z disc [GO:0030018] actin filament binding [GO:0051015]; ankyrin binding [GO:0030506]; cadherin binding [GO:0045296]; dystroglycan binding [GO:0002162]; protein self-association [GO:0043621]; RNA binding [GO:0003723]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307] 0.9689 -16.188 AAAGKAELELELGRIR 0 0 9.24241 9.04174 0 0 10.151 0 0 10.4535 13.1102 12.6831 0 10.9441 0 9.38729 10.8187 10.4664 10.2228 12.1149 0 10.8066 0 0 9.88087 8.97997 11.8301 Q15154 PCM1_HUMAN Pericentriolar material 1 protein (PCM-1) (hPCM-1) PCM1 Homo sapiens (Human) centrosome cycle [GO:0007098]; cilium assembly [GO:0060271]; cytoplasmic microtubule organization [GO:0031122]; interkinetic nuclear migration [GO:0022027]; intraciliary transport involved in cilium assembly [GO:0035735]; microtubule anchoring [GO:0034453]; microtubule anchoring at centrosome [GO:0034454]; negative regulation of neurogenesis [GO:0050768]; neuron migration [GO:0001764]; neuronal stem cell population maintenance [GO:0097150]; non-motile cilium assembly [GO:1905515]; positive regulation of intracellular protein transport [GO:0090316]; protein localization to centrosome [GO:0071539]; protein-containing complex localization to centriolar satellite [GO:0140706]; regulation of protein complex stability [GO:0061635]; social behavior [GO:0035176] apical part of cell [GO:0045177]; centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary transition zone [GO:0035869]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; pericentriolar material [GO:0000242]; protein-containing complex [GO:0032991] identical protein binding [GO:0042802]; molecular adaptor activity [GO:0060090]; molecular function activator activity [GO:0140677] 0.96991 -3.0794 LLGELHTLR 0 0 0 0 0 0 0 0 10.2975 0 0 0 0 0 0 9.19463 0 11.3602 0 0 0 0 0 0 0 0 0 Q15166 PON3_HUMAN Serum paraoxonase/lactonase 3 (EC 3.1.1.2) (EC 3.1.1.81) (EC 3.1.8.1) PON3 Homo sapiens (Human) aromatic compound catabolic process [GO:0019439]; carboxylic acid catabolic process [GO:0046395]; coumarin catabolic process [GO:0046226]; establishment of localization in cell [GO:0051649]; negative regulation of superoxide anion generation [GO:0032929]; phenylacetate catabolic process [GO:0010124]; renal sodium ion transport [GO:0003096]; response to toxic substance [GO:0009636] endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615] "3,4-dihydrocoumarin hydrolase activity [GO:0018733]; acyl-L-homoserine-lactone lactonohydrolase activity [GO:0102007]; aryldialkylphosphatase activity [GO:0004063]; arylesterase activity [GO:0004064]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]" 0.84823 0.15679 NIHIMEK 0 0 8.84235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15170 TCAL1_HUMAN Transcription elongation factor A protein-like 1 (TCEA-like protein 1) (Nuclear phosphoprotein p21/SIIR) (Transcription elongation factor S-II protein-like 1) TCEAL1 SIIR Homo sapiens (Human) nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.93905 -1.3199 DKPRKENEEEPQSAPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0921 10.3749 0 0 0 Q15181 IPYR_HUMAN Inorganic pyrophosphatase (EC 3.6.1.1) (Pyrophosphate phospho-hydrolase) (PPase) PPA1 IOPPP PP Homo sapiens (Human) phosphate-containing compound metabolic process [GO:0006796] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062] inorganic diphosphate phosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287] 0 3.3113 AAPFSLEYR 0 0 0 0 0 0 0 0 8.5529 9.87676 0 8.67642 0 9.48008 0 0 0 0 0 0 9.48559 0 0 9.28603 0 0 0 Q15185 TEBP_HUMAN Prostaglandin E synthase 3 (EC 5.3.99.3) (Cytosolic prostaglandin E2 synthase) (cPGES) (Hsp90 co-chaperone) (Progesterone receptor complex p23) (Telomerase-binding protein p23) PTGES3 P23 TEBP Homo sapiens (Human) chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; cyclooxygenase pathway [GO:0019371]; fibroblast proliferation [GO:0048144]; glucocorticoid receptor signaling pathway [GO:0042921]; glycogen biosynthetic process [GO:0005978]; lung saccule development [GO:0060430]; positive regulation of phosphorylation [GO:0042327]; positive regulation of telomerase activity [GO:0051973]; prostaglandin biosynthetic process [GO:0001516]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; signal transduction [GO:0007165]; skin development [GO:0043588]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance [GO:0000723]; telomere maintenance via telomerase [GO:0007004] "chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein folding chaperone complex [GO:0101031]; protein-containing complex [GO:0032991]; telomerase holoenzyme complex [GO:0005697]" DNA polymerase binding [GO:0070182]; Hsp90 protein binding [GO:0051879]; prostaglandin-E synthase activity [GO:0050220]; protein-folding chaperone binding [GO:0051087]; telomerase activity [GO:0003720]; unfolded protein binding [GO:0051082] 0.89758 -0.55029 SILCCLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8188 0 0 0 0 0 0 0 Q15198 PGFRL_HUMAN Platelet-derived growth factor receptor-like protein (PDGFR-like protein) (PDGF receptor beta-like tumor suppressor) PDGFRL PRLTS Homo sapiens (Human) extracellular region [GO:0005576] platelet activating factor receptor activity [GO:0004992]; platelet-derived growth factor beta-receptor activity [GO:0005019] 0.88334 -0.10568 RPKEPGENRIKPTNK 0 0 0 0 0 0 0 0 0 0 0 0 0 8.99977 0 10.0119 0 9.99605 0 0 0 0 0 0 0 0 0 Q15233 NONO_HUMAN "Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit)" NONO NRB54 Homo sapiens (Human) activation of innate immune response [GO:0002218]; circadian rhythm [GO:0007623]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; mRNA processing [GO:0006397]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-templated transcription [GO:0006355]; RNA splicing [GO:0008380] chromosome [GO:0005694]; fibrillar center [GO:0001650]; membrane [GO:0016020]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; RNA polymerase II transcription regulator complex [GO:0090575] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; RNA binding [GO:0003723] 0.23044 0.85605 AGEVFIHKDK 0 0 0 0 9.63535 0 9.12055 0 0 0 0 0 0 9.5686 0 10.0697 0 0 0 0 0 10.3753 0 0 11.2475 10.1616 10.3446 Q15256 PTPRR_HUMAN Receptor-type tyrosine-protein phosphatase R (R-PTP-R) (EC 3.1.3.48) (Ch-1PTPase) (NC-PTPCOM1) (Protein-tyrosine phosphatase PCPTP1) PTPRR ECPTP PTPRQ Homo sapiens (Human) ERBB2 signaling pathway [GO:0038128]; in utero embryonic development [GO:0001701]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; signal transduction [GO:0007165] cell junction [GO:0030054]; cytosol [GO:0005829]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001] 0.96936 -3.0563 NEKCVLYWPEK 8.9377 0 0 0 0 0 0 0 0 0 0 0 9.54969 0 0 0 0 0 0 10.224 0 0 9.39928 0 0 0 0 Q15257 PTPA_HUMAN "Serine/threonine-protein phosphatase 2A activator (EC 5.2.1.8) (PP2A, subunit B', PR53 isoform) (Phosphotyrosyl phosphatase activator) (PTPA) (Serine/threonine-protein phosphatase 2A regulatory subunit 4) (Serine/threonine-protein phosphatase 2A regulatory subunit B')" PTPA PPP2R4 Homo sapiens (Human) mitotic spindle organization [GO:0007052]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of protein dephosphorylation [GO:0035308]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of phosphoprotein phosphatase activity [GO:0043666] ATPase complex [GO:1904949]; calcium channel complex [GO:0034704]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein phosphatase type 2A complex [GO:0000159] ATP binding [GO:0005524]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein homodimerization activity [GO:0042803]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase regulator activity [GO:0019888]; protein tyrosine phosphatase activator activity [GO:0008160]; signaling receptor binding [GO:0005102] 0.96612 -2.3573 EIHTVPDMGKWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.46675 0 0 0 0 0 0 0 0 Q15262 PTPRK_HUMAN Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48) PTPRK PTPK Homo sapiens (Human) cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; focal adhesion assembly [GO:0048041]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of keratinocyte proliferation [GO:0010839]; protein dephosphorylation [GO:0006470]; protein localization to cell surface [GO:0034394]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179] adherens junction [GO:0005912]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; intracellular membrane-bounded organelle [GO:0043231]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; plasma membrane [GO:0005886] beta-catenin binding [GO:0008013]; gamma-catenin binding [GO:0045295]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001] 0.85528 0.1034 ADCLDMDPK 0 0 9.37918 0 0 0 0 0 0 0 0 0 0 0 0 9.43192 0 0 10.1173 0 0 0 0 0 0 0 0 Q15276 RABE1_HUMAN Rab GTPase-binding effector protein 1 (Rabaptin-4) (Rabaptin-5) (Rabaptin-5alpha) (Renal carcinoma antigen NY-REN-17) RABEP1 RAB5EP RABPT5 RABPT5A Homo sapiens (Human) apoptotic process [GO:0006915]; endocytosis [GO:0006897]; Golgi to plasma membrane transport [GO:0006893]; membrane fusion [GO:0061025]; protein localization to ciliary membrane [GO:1903441]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endosome [GO:0005768]; intracellular membrane-bounded organelle [GO:0043231]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037] growth factor activity [GO:0008083]; GTPase activator activity [GO:0005096]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803] 0.9147 -0.81593 ALGYNYKAK 10.0371 0 0 0 0 0 0 0 0 9.88981 0 8.87689 0 0 0 9.90576 0 0 0 0 0 0 0 0 0 0 0 Q15287 RNPS1_HUMAN RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2) RNPS1 LDC2 Homo sapiens (Human) "DNA-templated transcription [GO:0006351]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of apoptotic process [GO:0043065]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]" ASAP complex [GO:0061574]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723] 0.962 -2.6097 KSLLGVK 0 0 0 0 0 0 0 0 0 0 0 10.1262 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15291 RBBP5_HUMAN Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3) RBBP5 RBQ3 Homo sapiens (Human) DNA damage response [GO:0006974]; histone H3-K4 methylation [GO:0051568]; response to estrogen [GO:0043627]; transcription initiation-coupled chromatin remodeling [GO:0045815] histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL1/2 complex [GO:0044665]; MLL3/4 complex [GO:0044666]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188] histone binding [GO:0042393]; transcription cis-regulatory region binding [GO:0000976] 0.76373 0.28702 SAPVMLTLSDSK 0 0 0 0 0 0 0 0 0 0 0 8.79951 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15293 RCN1_HUMAN Reticulocalbin-1 RCN1 RCN Homo sapiens (Human) camera-type eye development [GO:0043010]; in utero embryonic development [GO:0001701] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788] calcium ion binding [GO:0005509] 0.60029 0.442 AADLNGDLTATR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.60607 0 0 0 0 0 0 Q15303 ERBB4_HUMAN Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)] ERBB4 HER4 Homo sapiens (Human) cardiac muscle tissue regeneration [GO:0061026]; cell fate commitment [GO:0045165]; cell migration [GO:0016477]; cellular response to epidermal growth factor stimulus [GO:0071364]; central nervous system morphogenesis [GO:0021551]; embryonic pattern specification [GO:0009880]; ERBB2-ERBB4 signaling pathway [GO:0038135]; ERBB4 signaling pathway [GO:0038130]; ERBB4-ERBB4 signaling pathway [GO:0038138]; establishment of planar polarity involved in nephron morphogenesis [GO:0072046]; heart development [GO:0007507]; lactation [GO:0007595]; mammary gland alveolus development [GO:0060749]; mammary gland epithelial cell differentiation [GO:0060644]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neurogenesis [GO:0022008]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; olfactory bulb interneuron differentiation [GO:0021889]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein autophosphorylation [GO:0046777]; regulation of cell migration [GO:0030334]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; extracellular region [GO:0005576]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235] ATP binding [GO:0005524]; epidermal growth factor receptor activity [GO:0005006]; epidermal growth factor receptor binding [GO:0005154]; GABA receptor binding [GO:0050811]; neuregulin receptor activity [GO:0038131]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transcription cis-regulatory region binding [GO:0000976]; transmembrane receptor protein tyrosine kinase activity [GO:0004714] 0.91474 -0.81365 CWGPTENHCQTLTRTVCAEQCDGR 0 0 0 10.0959 0 9.86777 10.3616 0 0 0 0 10.6159 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15311 RBP1_HUMAN "RalA-binding protein 1 (RalBP1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase) (EC 7.6.2.2, EC 7.6.2.3) (Ral-interacting protein 1)" RALBP1 RLIP RLIP1 RLIP76 Homo sapiens (Human) chemotaxis [GO:0006935]; doxorubicin transport [GO:1900753]; endocytosis [GO:0006897]; positive regulation of GTPase activity [GO:0043547]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of protein phosphorylation [GO:0001934]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264]; transmembrane transport [GO:0055085]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961] cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; spindle pole [GO:0000922] ABC-type glutathione S-conjugate transporter activity [GO:0015431]; ABC-type xenobiotic transporter activity [GO:0008559]; ATP binding [GO:0005524]; ATPase-coupled transmembrane transporter activity [GO:0042626]; GTPase activator activity [GO:0005096]; small GTPase binding [GO:0031267]; transmembrane transporter activity [GO:0022857]; xenobiotic transmembrane transporter activity [GO:0042910] 0.96876 -3.9329 DGVLEPKAAK 0 0 0 11.1583 0 0 0 0 0 0 0 0 0 10.658 0 0 0 0 0 0 0 0 0 0 9.90552 0 0 Q15327 ANKR1_HUMAN Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible gene C-193 protein) (Cytokine-inducible nuclear protein) ANKRD1 C193 CARP HA1A2 Homo sapiens (Human) "cardiac muscle tissue morphogenesis [GO:0055008]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to xenobiotic stimulus [GO:0071466]; negative regulation of DNA biosynthetic process [GO:2000279]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; positive regulation of protein secretion [GO:0050714]; protein kinase C signaling [GO:0070528]; regulation of transcription by RNA polymerase II [GO:0006357]; response to muscle stretch [GO:0035994]; sarcomere organization [GO:0045214]; skeletal muscle cell differentiation [GO:0035914]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; I band [GO:0031674]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] DNA binding [GO:0003677]; histone deacetylase binding [GO:0042826]; p53 binding [GO:0002039]; R-SMAD binding [GO:0070412]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; titin binding [GO:0031432]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714] 0.90483 -0.73009 LNRYKMIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.98996 0 0 0 0 0 0 0 Q15329 E2F5_HUMAN Transcription factor E2F5 (E2F-5) E2F5 Homo sapiens (Human) cell projection organization [GO:0030030]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; RNA polymerase II transcription regulator complex [GO:0090575] "DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein dimerization activity [GO:0046983]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.95207 -1.4482 AEIEDLELK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5413 0 0 0 0 0 0 0 Q15334 L2GL1_HUMAN Lethal(2) giant larvae protein homolog 1 (LLGL) (DLG4) (Hugl-1) (Human homolog to the D-lgl gene protein) LLGL1 DLG4 HUGL HUGL1 Homo sapiens (Human) axonogenesis [GO:0007409]; cortical actin cytoskeleton organization [GO:0030866]; establishment of spindle orientation [GO:0051294]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; protein-containing complex assembly [GO:0065003]; regulation of establishment or maintenance of cell polarity [GO:0032878]; regulation of Notch signaling pathway [GO:0008593]; regulation of protein secretion [GO:0050708] adherens junction [GO:0005912]; axon [GO:0030424]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; early endosome membrane [GO:0031901]; Golgi cis cisterna [GO:0000137]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588] GTPase activator activity [GO:0005096]; myosin II binding [GO:0045159]; protein kinase binding [GO:0019901]; structural molecule activity [GO:0005198] 0.95109 -1.3838 LTAHEGCR 0 0 0 0 0 0 0 0 0 0 9.20048 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15349 KS6A2_HUMAN Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (p90RSK2) (MAP kinase-activated protein kinase 1c) (MAPK-activated protein kinase 1c) (MAPKAP kinase 1c) (MAPKAPK-1c) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) RPS6KA2 MAPKAPK1C RSK3 Homo sapiens (Human) brain renin-angiotensin system [GO:0002035]; cardiac muscle cell apoptotic process [GO:0010659]; cellular response to carbohydrate stimulus [GO:0071322]; chemical synaptic transmission [GO:0007268]; heart contraction [GO:0060047]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of meiotic nuclear division [GO:0045835]; oocyte maturation [GO:0001556]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic process [GO:0043065]; positive regulation of gene expression [GO:0010628]; regulation of protein processing [GO:0070613]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; meiotic spindle [GO:0072687]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; synapse [GO:0045202] ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; ribosomal protein S6 kinase activity [GO:0004711] 0.95833 -1.6864 EAIDHDK 0 0 0 0 0 0 12.8114 0 0 0 8.7039 8.63005 8.71235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15361 TTF1_HUMAN Transcription termination factor 1 (TTF-1) (RNA polymerase I termination factor) (Transcription termination factor I) (TTF-I) TTF1 Homo sapiens (Human) DNA-templated transcription termination [GO:0006353]; negative regulation of DNA replication [GO:0008156]; termination of RNA polymerase I transcription [GO:0006363] fibrillar center [GO:0001650]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; DNA binding [GO:0003677] 0.9645 -2.6857 AKKMFDVNNYK 0 0 0 0 0 0 8.98123 0 0 0 0 0 0 0 0 0 0 0 10.1311 0 0 0 0 0 0 0 9.74096 Q15365 PCBP1_HUMAN Poly(rC)-binding protein 1 (Alpha-CP1) (Heterogeneous nuclear ribonucleoprotein E1) (hnRNP E1) (Nucleic acid-binding protein SUB2.3) PCBP1 Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944]; viral RNA genome replication [GO:0039694] cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; ribonucleoprotein complex [GO:1990904] "cadherin binding [GO:0045296]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; sequence-specific single stranded DNA binding [GO:0098847]; single-stranded DNA binding [GO:0003697]" 0 15.679 ESTGAQVQVAGDMLPNSTER 8.95841 8.8415 9.96485 0 0 0 10.5512 11.1798 10.8277 9.85161 10.9369 10.193 10.8708 10.278 10.216 11.1068 11.2744 11.4495 10.5377 9.32314 10.5396 9.86821 9.78532 9.439 11.8217 11.8659 11.3142 Q15366 PCBP2_HUMAN Poly(rC)-binding protein 2 (Alpha-CP2) (Heterogeneous nuclear ribonucleoprotein E2) (hnRNP E2) PCBP2 Homo sapiens (Human) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; IRES-dependent viral translational initiation [GO:0075522]; mRNA metabolic process [GO:0016071]; negative regulation of defense response to virus [GO:0050687]; negative regulation of innate immune response [GO:0045824]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of gene expression [GO:0010468]; regulation of RNA metabolic process [GO:0051252]; viral RNA genome replication [GO:0039694] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; ribonucleoprotein complex [GO:1990904] C-rich single-stranded DNA binding [GO:1990829]; enzyme binding [GO:0019899]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; ubiquitin protein ligase binding [GO:0031625] 0 6.4308 ESTGAQVQVAGDMLPNSTER 0 0 0 0 0 0 0 0 0 0 0 0 0 9.01703 0 9.00135 8.98891 0 0 9.4747 9.52089 9.01661 0 9.25238 10.4626 10.4019 10.7903 Q15370 ELOB_HUMAN Elongin-B (EloB) (Elongin 18 kDa subunit) (RNA polymerase II transcription factor SIII subunit B) (SIII p18) (Transcription elongation factor B polypeptide 2) ELOB TCEB2 Homo sapiens (Human) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; target-directed miRNA degradation [GO:0140958]; transcription elongation by RNA polymerase II [GO:0006368]; transcription initiation at RNA polymerase II promoter [GO:0006367] Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891] transcription corepressor binding [GO:0001222]; ubiquitin protein ligase binding [GO:0031625] 0.93957 -1.3034 RHKTTIFTDAK 0 0 0 0 0 9.98071 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15375 EPHA7_HUMAN Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11) EPHA7 EHK3 HEK11 Homo sapiens (Human) axon guidance [GO:0007411]; brain development [GO:0007420]; branching morphogenesis of a nerve [GO:0048755]; ephrin receptor signaling pathway [GO:0048013]; modulation of chemical synaptic transmission [GO:0050804]; negative chemotaxis [GO:0050919]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of synapse assembly [GO:0051964]; nephric duct morphogenesis [GO:0072178]; neuron apoptotic process [GO:0051402]; phosphorylation [GO:0016310]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein phosphorylation [GO:0001934]; protein phosphorylation [GO:0006468]; regulation of cell-cell adhesion [GO:0022407]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of postsynapse organization [GO:0099175]; regulation of protein autophosphorylation [GO:0031952]; retinal ganglion cell axon guidance [GO:0031290] dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; Schaffer collateral - CA1 synapse [GO:0098685] ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; chemorepellent activity [GO:0045499]; ephrin receptor binding [GO:0046875]; GPI-linked ephrin receptor activity [GO:0005004]; growth factor binding [GO:0019838]; protein tyrosine kinase activity [GO:0004713]; transmembrane-ephrin receptor activity [GO:0005005] 0.89825 -0.68351 FTLRDCNSLPGVLGTCK 11.9439 0 0 0 0 0 10.3057 0 0 0 9.75345 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15386 UBE3C_HUMAN Ubiquitin-protein ligase E3C (EC 2.3.2.26) (HECT-type ubiquitin transferase E3C) (Homologous to E6AP carboxyl terminus homologous protein 2) (HectH2) (RTA-associated ubiquitin ligase) (RAUL) UBE3C KIAA0010 KIAA10 Homo sapiens (Human) protein K29-linked ubiquitination [GO:0035519]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] proteasome complex [GO:0000502] kinase inhibitor activity [GO:0019210]; ubiquitin protein ligase activity [GO:0061630] 0.92266 -0.9411 LSPENEPDLK 0 0 0 0 0 0 0 0 11.1364 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15388 TOM20_HUMAN Mitochondrial import receptor subunit TOM20 homolog (Mitochondrial 20 kDa outer membrane protein) (Outer mitochondrial membrane receptor Tom20) TOMM20 KIAA0016 Homo sapiens (Human) protein import into mitochondrial matrix [GO:0030150]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein targeting to mitochondrion [GO:0006626]; tRNA import into mitochondrion [GO:0016031] cell periphery [GO:0071944]; migrasome [GO:0140494]; mitochondria-associated endoplasmic reticulum membrane [GO:0044233]; mitochondrial outer membrane [GO:0005741]; mitochondrial outer membrane translocase complex [GO:0005742]; mitochondrion [GO:0005739]; sperm midpiece [GO:0097225] mitochondrion targeting sequence binding [GO:0030943]; protein-transporting ATPase activity [GO:0015450]; unfolded protein binding [GO:0051082] 0.1874 0.94373 IVSAQSLAEDDVE 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.3376 0 0 9.58289 10.2656 0 11.3006 0 Q15389 ANGP1_HUMAN Angiopoietin-1 (ANG-1) ANGPT1 KIAA0003 Homo sapiens (Human) activation of transmembrane receptor protein tyrosine kinase activity [GO:0007171]; angiogenesis [GO:0001525]; cell-substrate adhesion [GO:0031589]; glomerulus vasculature development [GO:0072012]; hemopoiesis [GO:0030097]; heparin biosynthetic process [GO:0030210]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cytokine production involved in immune response [GO:0002719]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein import into nucleus [GO:0042308]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of vascular permeability [GO:0043116]; neuron apoptotic process [GO:0051402]; positive chemotaxis [GO:0050918]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood-brain barrier permeability [GO:1905605]; positive regulation of cell adhesion [GO:0045785]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of receptor internalization [GO:0002092]; protein localization to cell surface [GO:0034394]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of macrophage migration inhibitory factor signaling pathway [GO:2000446]; regulation of protein binding [GO:0043393]; regulation of skeletal muscle satellite cell proliferation [GO:0014842]; regulation of tumor necrosis factor production [GO:0032680]; sprouting angiogenesis [GO:0002040]; Tie signaling pathway [GO:0048014] collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane raft [GO:0045121]; microvillus [GO:0005902]; plasma membrane [GO:0005886] identical protein binding [GO:0042802]; receptor tyrosine kinase binding [GO:0030971] 0.86393 0.087153 LNGIKWHYFK 0 0 10.5349 0 0 0 0 0 0 0 0 0 0 9.30615 0 0 0 0 0 0 0 0 0 9.94061 0 0 0 Q15391 P2Y14_HUMAN P2Y purinoceptor 14 (P2Y14) (G-protein coupled receptor 105) (UDP-glucose receptor) P2RY14 GPR105 KIAA0001 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186] membrane [GO:0016020]; plasma membrane [GO:0005886] G protein-coupled purinergic nucleotide receptor activity [GO:0045028]; G protein-coupled UDP receptor activity [GO:0045029] 0.9601 -1.9835 IFKSHLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.31615 0 Q15392 DHC24_HUMAN Delta(24)-sterol reductase (EC 1.3.1.72) (24-dehydrocholesterol reductase) (3-beta-hydroxysterol Delta-24-reductase) (Diminuto/dwarf1 homolog) (Seladin-1) DHCR24 KIAA0018 Homo sapiens (Human) amyloid precursor protein catabolic process [GO:0042987]; apoptotic process [GO:0006915]; cholesterol biosynthetic process [GO:0006695]; cholesterol biosynthetic process via desmosterol [GO:0033489]; cholesterol biosynthetic process via lathosterol [GO:0033490]; male genitalia development [GO:0030539]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; plasminogen activation [GO:0031639]; protein localization [GO:0008104]; Ras protein signal transduction [GO:0007265]; regulation of cell cycle [GO:0051726]; regulation of neuron death [GO:1901214]; response to hormone [GO:0009725]; response to oxidative stress [GO:0006979]; skin development [GO:0043588]; steroid metabolic process [GO:0008202]; tissue development [GO:0009888] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; nucleus [GO:0005634] "delta24(24-1) sterol reductase activity [GO:0000246]; delta24-sterol reductase activity [GO:0050614]; enzyme binding [GO:0019899]; FAD binding [GO:0071949]; oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [GO:0016628]; peptide antigen binding [GO:0042605]" 0 3.4995 EGLEYIPLR 8.96829 9.12166 0 10.3144 0 0 10.0199 9.94916 10.8911 0 0 0 0 9.94436 0 0 0 0 0 0 0 0 0 0 0 10.7579 0 Q15393 SF3B3_HUMAN Splicing factor 3B subunit 3 (Pre-mRNA-splicing factor SF3b 130 kDa subunit) (SF3b130) (STAF130) (Spliceosome-associated protein 130) (SAP 130) SF3B3 KIAA0017 SAP130 Homo sapiens (Human) "histone H3 acetylation [GO:0043966]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of protein catabolic process [GO:0042177]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA repair [GO:0006282]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]; U2-type prespliceosome assembly [GO:1903241]" catalytic step 2 spliceosome [GO:0071013]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SAGA complex [GO:0000124]; spliceosomal complex [GO:0005681]; U12-type spliceosomal complex [GO:0005689]; U2 snRNP [GO:0005686]; U2-type precatalytic spliceosome [GO:0071005]; U2-type spliceosomal complex [GO:0005684] protein-containing complex binding [GO:0044877]; U2 snRNA binding [GO:0030620] 0.96894 -4.4384 ADKRVNEWK 0 0 0 0 11.3035 0 0 0 10.0641 0 0 0 0 0 0 0 0 0 10.5851 0 0 9.58646 0 0 10.1762 0 0 Q15397 PUM3_HUMAN Pumilio homolog 3 (HBV X-transactivated gene 5 protein) (HBV XAg-transactivated protein 5) (Minor histocompatibility antigen HA-8) (HLA-HA8) PUM3 cPERP-C KIAA0020 PUF-A XTP5 Homo sapiens (Human) regulation of protein ADP-ribosylation [GO:0010835]; regulation of translation [GO:0006417] chromosome [GO:0005694]; endoplasmic reticulum [GO:0005783]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] DNA binding [GO:0003677]; mRNA binding [GO:0003729]; RNA binding [GO:0003723] 0.92311 -1.1462 ENGREGCFAK 0 0 0 0 0 0 0 0 0 0 9.43206 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15398 DLGP5_HUMAN Disks large-associated protein 5 (DAP-5) (Discs large homolog 7) (Disks large-associated protein DLG7) (Hepatoma up-regulated protein) (HURP) DLGAP5 DLG7 KIAA0008 Homo sapiens (Human) centrosome localization [GO:0051642]; chromosome segregation [GO:0007059]; kinetochore assembly [GO:0051382]; mitotic chromosome movement towards spindle pole [GO:0007079]; mitotic spindle organization [GO:0007052]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; regulation of mitotic cell cycle [GO:0007346]; signaling [GO:0023052] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitotic spindle [GO:0072686]; nucleus [GO:0005634]; spindle pole centrosome [GO:0031616] microtubule binding [GO:0008017] 0.96917 -3.3962 EVPSLERNEGR 0 0 0 0 0 0 0 0 0 0 11.0476 0 0 0 0 10.0664 0 0 0 0 0 0 0 0 0 0 0 Q15399 TLR1_HUMAN Toll-like receptor 1 (Toll/interleukin-1 receptor-like protein) (TIL) (CD antigen CD281) TLR1 KIAA0012 Homo sapiens (Human) cellular response to triacyl bacterial lipopeptide [GO:0071727]; detection of triacyl bacterial lipopeptide [GO:0042495]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; macrophage activation [GO:0042116]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of toll-like receptor 2 signaling pathway [GO:0034137]; positive regulation of tumor necrosis factor production [GO:0032760]; signal transduction [GO:0007165]; toll-like receptor signaling pathway [GO:0002224] Golgi apparatus [GO:0005794]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; Toll-like receptor 1-Toll-like receptor 2 protein complex [GO:0035354] "identical protein binding [GO:0042802]; lipopeptide binding [GO:0071723]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; signaling receptor activity [GO:0038023]; Toll-like receptor 2 binding [GO:0035663]; transmembrane signaling receptor activity [GO:0004888]" 0.079304 1.2376 IQYLDISVFK 0 0 0 0 0 0 0 0 0 0 0 11.6815 0 0 0 11.7114 0 0 0 0 0 0 0 0 0 0 0 Q15413 RYR3_HUMAN Ryanodine receptor 3 (RYR-3) (RyR3) (Brain ryanodine receptor-calcium release channel) (Brain-type ryanodine receptor) (Type 3 ryanodine receptor) RYR3 HBRR Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cellular response to ATP [GO:0071318]; cellular response to caffeine [GO:0071313]; cellular response to calcium ion [GO:0071277]; cellular response to magnesium ion [GO:0071286]; intracellular calcium ion homeostasis [GO:0006874]; protein homotetramerization [GO:0051289]; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0014808]; striated muscle contraction [GO:0006941] calcium channel complex [GO:0034704]; membrane [GO:0016020]; sarcolemma [GO:0042383]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; smooth endoplasmic reticulum [GO:0005790]; Z disc [GO:0030018] calcium ion binding [GO:0005509]; calcium-induced calcium release activity [GO:0048763]; calcium-release channel activity [GO:0015278]; calmodulin binding [GO:0005516]; ryanodine-sensitive calcium-release channel activity [GO:0005219] 0.96781 -3.6737 ALSMLTEAVQCSGAHIR 0 0 0 0 8.84515 10.3144 9.09149 0 0 0 0 0 0 0 0 11.1377 10.7746 0 9.52017 0 7.88637 0 8.97968 0 0 10.4888 0 Q15417 CNN3_HUMAN "Calponin-3 (Calponin, acidic isoform)" CNN3 Homo sapiens (Human) actin filament organization [GO:0007015]; actomyosin structure organization [GO:0031032]; epithelial cell differentiation [GO:0030855] actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; cytosol [GO:0005829]; focal adhesion [GO:0005925] actin filament binding [GO:0051015]; cadherin binding involved in cell-cell adhesion [GO:0098641]; calmodulin binding [GO:0005516] 0.01 1.8701 DGIILCELINK 12.879 0 12.7912 0 0 10.4722 0 9.09898 0 0 11.8364 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1477 Q15418 KS6A1_HUMAN Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (p90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPK-activated protein kinase 1a) (MAPKAP kinase 1a) (MAPKAPK-1a) (Ribosomal S6 kinase 1) (RSK-1) RPS6KA1 MAPKAPK1A RSK1 Homo sapiens (Human) cell cycle [GO:0007049]; chemical synaptic transmission [GO:0007268]; hepatocyte proliferation [GO:0072574]; intracellular signal transduction [GO:0035556]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of TOR signaling [GO:0032007]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell growth [GO:0030307]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of hepatic stellate cell activation [GO:2000491]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of translation in response to stress [GO:0043555]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; synapse [GO:0045202] ATP binding [GO:0005524]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; magnesium ion binding [GO:0000287]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; ribosomal protein S6 kinase activity [GO:0004711] 0.45026 0.64286 EAIDHEKKAYSFCGTVEYMAPEVVNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.64595 0 0 0 0 0 0 0 0 0 0 Q15424 SAFB1_HUMAN Scaffold attachment factor B1 (SAF-B) (SAF-B1) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE-TATA-binding protein) SAFB HAP HET SAFB1 Homo sapiens (Human) chromatin organization [GO:0006325]; intracellular estrogen receptor signaling pathway [GO:0030520]; regulation of mRNA processing [GO:0050684]; regulation of transcription by RNA polymerase II [GO:0006357] midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565] 0.78923 0.25116 AETLSGLGDSGAAGAAALSSASSETGTR 9.22887 0 0 0 0 0 0 0 0 11.7282 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15431 SYCP1_HUMAN Synaptonemal complex protein 1 (SCP-1) (Cancer/testis antigen 8) (CT8) SYCP1 SCP1 Homo sapiens (Human) cell division [GO:0051301]; chiasma assembly [GO:0051026]; homologous chromosome pairing at meiosis [GO:0007129]; lateral element assembly [GO:0051878]; meiotic DNA repair synthesis [GO:0000711]; protein homotetramerization [GO:0051289]; reciprocal meiotic recombination [GO:0007131]; regulation of protein localization [GO:0032880]; sperm DNA condensation [GO:0035092]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130] "autosome [GO:0030849]; central element [GO:0000801]; chromosome [GO:0005694]; chromosome, centromeric region [GO:0000775]; male germ cell nucleus [GO:0001673]; synaptonemal complex [GO:0000795]; transverse filament [GO:0000802]" DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690] 0.96896 -6.7065 CTEDDFEFPFAK 0 0 0 10.6317 11.0229 10.5828 9.39812 0 9.43804 0 9.08478 0 11.0183 0 0 0 9.97642 11.4772 10.3168 9.46395 9.30483 0 9.75957 10.8113 0 0 0 Q15434 RBMS2_HUMAN "RNA-binding motif, single-stranded-interacting protein 2 (Suppressor of CDC2 with RNA-binding motif 3)" RBMS2 SCR3 Homo sapiens (Human) RNA processing [GO:0006396] cytosol [GO:0005829]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723] 0.66157 0.39471 FADGGPK 0 0 0 8.45409 0 8.72455 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15435 PP1R7_HUMAN Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22) PPP1R7 SDS22 Homo sapiens (Human) positive regulation of protein dephosphorylation [GO:0035307] chromosome [GO:0005694]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleus [GO:0005634] enzyme regulator activity [GO:0030234]; protein phosphatase regulator activity [GO:0019888] 0.91579 -0.77312 LFLVNNK 10.9127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15437 SC23B_HUMAN Protein transport protein Sec23B (hSec23B) (SEC23-related protein B) SEC23B Homo sapiens (Human) COPII-coated vesicle cargo loading [GO:0090110]; intracellular protein transport [GO:0006886] COPII vesicle coat [GO:0030127]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; perinuclear region of cytoplasm [GO:0048471] GTPase activator activity [GO:0005096]; zinc ion binding [GO:0008270] 0.51292 0.60177 ATYLEFIQQNEER 10.3665 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.382 0 0 0 0 0 0 0 9.30453 0 9.3413 Q15459 SF3A1_HUMAN Splicing factor 3A subunit 1 (SF3a120) (Spliceosome-associated protein 114) (SAP 114) SF3A1 SAP114 Homo sapiens (Human) "mRNA 3'-splice site recognition [GO:0000389]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; U2-type prespliceosome assembly [GO:1903241]" catalytic step 2 spliceosome [GO:0071013]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2 snRNP [GO:0005686]; U2-type precatalytic spliceosome [GO:0071005]; U2-type prespliceosome [GO:0071004]; U2-type spliceosomal complex [GO:0005684] RNA binding [GO:0003723] 0.95096 -1.4154 IPASKMQEHMR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0157 0 0 Q15464 SHB_HUMAN SH2 domain-containing adapter protein B SHB Homo sapiens (Human) angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; B cell proliferation [GO:0042100]; hematopoietic stem cell proliferation [GO:0071425]; negative regulation of oocyte maturation [GO:1900194]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of T-helper cell differentiation [GO:0045624]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852] cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] phosphotyrosine residue binding [GO:0001784]; signaling receptor complex adaptor activity [GO:0030159] 0.95548 -1.5583 RPATPAEVRYISPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.695 0 0 0 0 0 0 0 0 0 Q15465 SHH_HUMAN Sonic hedgehog protein (SHH) (EC 3.1.-.-) (HHG-1) (Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains) (ShhNC) [Cleaved into: Sonic hedgehog protein N-product (ShhN) (Shh N-terminal processed signaling domains) (ShhNp)] SHH Homo sapiens (Human) "alpha-beta T cell differentiation [GO:0046632]; alpha-tubulin acetylation [GO:0071929]; androgen metabolic process [GO:0008209]; animal organ formation [GO:0048645]; apoptotic signaling pathway [GO:0097190]; artery development [GO:0060840]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; blood coagulation [GO:0007596]; branching involved in blood vessel morphogenesis [GO:0001569]; branching involved in salivary gland morphogenesis [GO:0060445]; branching involved in ureteric bud morphogenesis [GO:0001658]; branching morphogenesis of an epithelial tube [GO:0048754]; bud outgrowth involved in lung branching [GO:0060447]; camera-type eye development [GO:0043010]; canonical Wnt signaling pathway [GO:0060070]; CD4-positive or CD8-positive, alpha-beta T cell lineage commitment [GO:0043369]; cell development [GO:0048468]; cell fate specification [GO:0001708]; cell-cell signaling [GO:0007267]; cellular response to lithium ion [GO:0071285]; central nervous system development [GO:0007417]; cerebellar granule cell precursor proliferation [GO:0021930]; determination of left/right asymmetry in lateral mesoderm [GO:0003140]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral neural tube patterning [GO:0021904]; dorsal/ventral pattern formation [GO:0009953]; ectoderm development [GO:0007398]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic digit morphogenesis [GO:0042733]; embryonic foregut morphogenesis [GO:0048617]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic skeletal system development [GO:0048706]; endocytosis [GO:0006897]; epithelial cell proliferation involved in prostate gland development [GO:0060767]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial-mesenchymal signaling involved in prostate gland development [GO:0060738]; establishment of epithelial cell polarity [GO:0090162]; forebrain development [GO:0030900]; formation of anatomical boundary [GO:0048859]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; hindbrain development [GO:0030902]; hindgut morphogenesis [GO:0007442]; inner ear development [GO:0048839]; intein-mediated protein splicing [GO:0016539]; intermediate filament organization [GO:0045109]; left lung development [GO:0060459]; limb bud formation [GO:0060174]; lung development [GO:0030324]; lung epithelium development [GO:0060428]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; lymphoid progenitor cell differentiation [GO:0002320]; male genitalia development [GO:0030539]; mesenchymal cell apoptotic process [GO:0097152]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesenchymal smoothened signaling pathway involved in prostate gland development [GO:0060783]; metanephric collecting duct development [GO:0072205]; metanephric mesenchymal cell proliferation involved in metanephros development [GO:0072136]; metanephros development [GO:0001656]; midbrain development [GO:0030901]; myoblast differentiation [GO:0045445]; negative regulation of alpha-beta T cell differentiation [GO:0046639]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell migration [GO:0030336]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of dopaminergic neuron differentiation [GO:1904339]; negative regulation of gene expression [GO:0010629]; negative regulation of kidney smooth muscle cell differentiation [GO:2000357]; negative regulation of mesenchymal cell apoptotic process [GO:2001054]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein binding [GO:0032091]; negative regulation of T cell differentiation in thymus [GO:0033085]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; negative regulation of ureter smooth muscle cell differentiation [GO:2000062]; negative thymic T cell selection [GO:0045060]; neural crest cell migration [GO:0001755]; neuroblast proliferation [GO:0007405]; neuron fate commitment [GO:0048663]; odontogenesis of dentin-containing tooth [GO:0042475]; oligodendrocyte development [GO:0014003]; oligodendrocyte differentiation [GO:0048709]; osteoblast development [GO:0002076]; pancreas development [GO:0031016]; pattern specification process [GO:0007389]; polarity specification of anterior/posterior axis [GO:0009949]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell proliferation involved in prostate gland development [GO:0060769]; positive regulation of gene expression [GO:0010628]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of immature T cell proliferation in thymus [GO:0033092]; positive regulation of kidney smooth muscle cell differentiation [GO:2000358]; positive regulation of mesenchymal cell proliferation involved in ureter development [GO:2000729]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of sclerotome development [GO:0061189]; positive regulation of skeletal muscle cell proliferation [GO:0014858]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of striated muscle cell differentiation [GO:0051155]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ureter smooth muscle cell differentiation [GO:2000063]; positive regulation of Wnt signaling pathway [GO:0030177]; positive thymic T cell selection [GO:0045059]; primary prostatic bud elongation [GO:0060516]; prostate epithelial cord elongation [GO:0060523]; prostate gland development [GO:0030850]; protein autoprocessing [GO:0016540]; protein import into nucleus [GO:0006606]; regulation of cell population proliferation [GO:0042127]; regulation of glial cell proliferation [GO:0060251]; regulation of mesenchymal cell proliferation involved in prostate gland development [GO:0060782]; regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry [GO:1900175]; regulation of odontogenesis [GO:0042481]; regulation of prostatic bud formation [GO:0060685]; regulation of protein localization to nucleus [GO:1900180]; regulation of proteolysis [GO:0030162]; regulation of stem cell proliferation [GO:0072091]; right lung development [GO:0060458]; roof of mouth development [GO:0060021]; salivary gland cavitation [GO:0060662]; self proteolysis [GO:0097264]; skeletal muscle cell proliferation [GO:0014856]; skeletal muscle fiber differentiation [GO:0098528]; smooth muscle tissue development [GO:0048745]; smoothened signaling pathway [GO:0007224]; smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation [GO:0021938]; somite development [GO:0061053]; spinal cord dorsal/ventral patterning [GO:0021513]; spinal cord motor neuron differentiation [GO:0021522]; stem cell development [GO:0048864]; stem cell proliferation [GO:0072089]; striated muscle tissue development [GO:0014706]; T cell differentiation in thymus [GO:0033077]; T cell proliferation [GO:0042098]; telencephalon regionalization [GO:0021978]; thalamus development [GO:0021794]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; trachea morphogenesis [GO:0060439]; tracheoesophageal septum formation [GO:1905327]; trunk neural crest cell migration [GO:0036484]; vasculogenesis [GO:0001570]; ventral midline development [GO:0007418]" cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane raft [GO:0045121]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; cholesterol-protein transferase activity [GO:0140853]; endopeptidase activity [GO:0004175]; glycosaminoglycan binding [GO:0005539]; laminin-1 binding [GO:0043237]; morphogen activity [GO:0016015]; patched binding [GO:0005113]; peptidase activity [GO:0008233]; zinc ion binding [GO:0008270] 0.94834 -1.3619 LLYSDFLTFLDRDDGAKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1746 0 0 Q15468 STIL_HUMAN SCL-interrupting locus protein (TAL-1-interrupting locus protein) STIL SIL Homo sapiens (Human) centrosome duplication [GO:0051298]; determination of left/right symmetry [GO:0007368]; embryonic axis specification [GO:0000578]; floor plate development [GO:0033504]; forebrain development [GO:0030900]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; mitotic spindle organization [GO:0007052]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; notochord development [GO:0030903]; positive regulation of centriole replication [GO:0046601]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of spindle assembly [GO:1905832]; protein localization to centrosome [GO:0071539]; regulation of centriole replication [GO:0046599]; regulation of mitotic spindle organization [GO:0060236]; smoothened signaling pathway [GO:0007224] centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; procentriole replication complex [GO:0120099] identical protein binding [GO:0042802] 0.95909 -1.8651 AEFTQHPEK 0 9.94458 0 0 0 0 0 10.3674 0 9.70989 0 0 0 0 9.66841 0 0 0 0 0 0 0 0 0 0 0 0 Q15477 SKI2_HUMAN Superkiller complex protein 2 (Ski2) (EC 3.6.4.13) (Helicase-like protein) (HLP) SKIC2 DDX13 SKI2W SKIV2 SKIV2L W Homo sapiens (Human) "nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay [GO:0070478]; rescue of stalled ribosome [GO:0072344]" cytosol [GO:0005829]; nucleus [GO:0005634]; Ski complex [GO:0055087] 3'-5' RNA helicase activity [GO:0034458]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.97001 -3.2657 EIVEMLFSR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.95537 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15493 RGN_HUMAN Regucalcin (RC) (Gluconolactonase) (GNL) (EC 3.1.1.17) (Senescence marker protein 30) (SMP-30) RGN SMP30 Homo sapiens (Human) aging [GO:0007568]; intracellular calcium ion homeostasis [GO:0006874]; kidney development [GO:0001822]; L-ascorbic acid biosynthetic process [GO:0019853]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone development [GO:1903011]; negative regulation of calcium-dependent ATPase activity [GO:1903611]; negative regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051344]; negative regulation of DNA biosynthetic process [GO:2000279]; negative regulation of DNA catabolic process [GO:1903625]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of flagellated sperm motility [GO:1901318]; negative regulation of GTPase activity [GO:0034260]; negative regulation of leucine-tRNA ligase activity [GO:1903634]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of RNA biosynthetic process [GO:1902679]; positive regulation of ATP-dependent activity [GO:0032781]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of dUTP diphosphatase activity [GO:1903629]; positive regulation of fatty acid biosynthetic process [GO:0045723]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phosphatase activity [GO:0010922]; positive regulation of proteolysis involved in protein catabolic process [GO:1903052]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of calcium-mediated signaling [GO:0050848]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] calcium ion binding [GO:0005509]; enzyme regulator activity [GO:0030234]; gluconolactonase activity [GO:0004341]; zinc ion binding [GO:0008270] 0.92173 -1.0894 KVCRWDSFTK 0 0 0 0 0 0 0 0 0 0 9.56352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15506 SP17_HUMAN Sperm surface protein Sp17 (Cancer/testis antigen 22) (CT22) (Sp17-1) (Sperm autoantigenic protein 17) (Sperm protein 17) SPA17 SP17 Homo sapiens (Human) binding of sperm to zona pellucida [GO:0007339]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; single fertilization [GO:0007338]; spermatogenesis [GO:0007283] cilium [GO:0005929]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; motile cilium [GO:0031514]; neuron projection [GO:0043005]; sperm fibrous sheath [GO:0035686]; sperm principal piece [GO:0097228] calmodulin binding [GO:0005516] 0.84114 0.17908 EEETSVTILDSSEEDK 0 0 0 0 0 0 0 0 0 10.3015 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15528 MED22_HUMAN Mediator of RNA polymerase II transcription subunit 22 (Mediator complex subunit 22) (Surfeit locus protein 5) (Surf-5) MED22 SURF5 Homo sapiens (Human) positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; RNA polymerase II preinitiation complex assembly [GO:0051123] core mediator complex [GO:0070847]; cytoplasm [GO:0005737]; mediator complex [GO:0016592]; nucleus [GO:0005634] transcription coregulator activity [GO:0003712] 0.96122 -2.5603 AGESLMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.2977 0 0 0 0 0 Q15542 TAF5_HUMAN Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100) TAF5 TAF2D Homo sapiens (Human) DNA-templated transcription initiation [GO:0006352]; histone H3 acetylation [GO:0043966]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription initiation at RNA polymerase II promoter [GO:0006367] actin cytoskeleton [GO:0015629]; chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor TFIID complex [GO:0005669]; transcription factor TFTC complex [GO:0033276] identical protein binding [GO:0042802]; RNA polymerase II general transcription initiation factor activity [GO:0016251] 0.91154 -0.7501 GHTDTVCSLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0091 0 Q15543 TAF13_HUMAN Transcription initiation factor TFIID subunit 13 (Transcription initiation factor TFIID 18 kDa subunit) (TAF(II)18) (TAFII-18) (TAFII18) TAF13 TAF2K TAFII18 Homo sapiens (Human) DNA-templated transcription initiation [GO:0006352]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; protein phosphorylation [GO:0006468]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transcription initiation at RNA polymerase II promoter [GO:0006367] nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor TFIID complex [GO:0005669] DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025] 0.92199 -1.1225 AMSIGRQGR 9.41574 0 0 0 0 0 0 9.99605 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15545 TAF7_HUMAN Transcription initiation factor TFIID subunit 7 (RNA polymerase II TBP-associated factor subunit F) (Transcription initiation factor TFIID 55 kDa subunit) (TAF(II)55) (TAFII-55) (TAFII55) TAF7 TAF2F TAFII55 Homo sapiens (Human) DNA-templated transcription initiation [GO:0006352]; histone H3 acetylation [GO:0043966]; intracellular estrogen receptor signaling pathway [GO:0030520]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of MHC class I biosynthetic process [GO:0045344]; negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA polymerase II preinitiation complex assembly [GO:0051123]; spermine transport [GO:0000296]; transcription by RNA polymerase II [GO:0006366]; transcription initiation at RNA polymerase II promoter [GO:0006367] cytoplasm [GO:0005737]; male germ cell nucleus [GO:0001673]; MLL1 complex [GO:0071339]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor TFIID complex [GO:0005669]; transcription factor TFTC complex [GO:0033276]; transcription regulator complex [GO:0005667] DNA-binding transcription factor binding [GO:0140297]; histone acetyltransferase binding [GO:0035035]; nuclear thyroid hormone receptor binding [GO:0046966]; nuclear vitamin D receptor binding [GO:0042809]; P-TEFb complex binding [GO:0106140]; protein heterodimerization activity [GO:0046982]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TFIIH-class transcription factor complex binding [GO:0001097]; transcription cis-regulatory region binding [GO:0000976] 0.91902 -0.89417 KFIWNHGITLPLKNVR 0 0 0 0 0 0 0 0 0 9.46048 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15560 TCEA2_HUMAN Transcription elongation factor A protein 2 (Testis-specific S-II) (Transcription elongation factor S-II protein 2) (Transcription elongation factor TFIIS.l) TCEA2 Homo sapiens (Human) DNA-templated transcription [GO:0006351]; DNA-templated transcription elongation [GO:0006354]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription elongation [GO:0032784]; transcription elongation by RNA polymerase II [GO:0006368] centrosome [GO:0005813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription elongation factor complex [GO:0008023] DNA binding [GO:0003677]; zinc ion binding [GO:0008270] 0.88395 -0.29722 ISNLKDAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.07044 0 0 0 0 0 Q15562 TEAD2_HUMAN Transcriptional enhancer factor TEF-4 (TEA domain family member 2) (TEAD-2) TEAD2 TEF4 Homo sapiens (Human) cellular response to retinoic acid [GO:0071300]; embryonic heart tube morphogenesis [GO:0003143]; embryonic organ development [GO:0048568]; hippo signaling [GO:0035329]; lateral mesoderm development [GO:0048368]; neural tube closure [GO:0001843]; notochord development [GO:0030903]; paraxial mesoderm development [GO:0048339]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein-containing complex assembly [GO:0065003]; regulation of DNA-templated transcription [GO:0006355]; regulation of stem cell differentiation [GO:2000736]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366]; vasculogenesis [GO:0001570] chromatin [GO:0000785]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; TEAD-YAP complex [GO:0140552]; transcription regulator complex [GO:0005667] "disordered domain specific binding [GO:0097718]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription coactivator binding [GO:0001223]" 0.88309 -0.05863 GAQHHIYR 8.61298 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15569 TESK1_HUMAN Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1) TESK1 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; establishment of vesicle localization [GO:0051650]; negative regulation of cilium assembly [GO:1902018]; negative regulation of phosphorylation [GO:0042326]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; podocyte cell migration [GO:0090521]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of protein localization [GO:0032880]; spermatogenesis [GO:0007283] centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; lamellipodium [GO:0030027]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein tyrosine kinase activity [GO:0004713] 0.93217 -1.2572 GLRYLHSK 0 0 0 0 0 0 0 0 0 9.47782 0 0 8.67751 0 0 8.48035 0 0 0 0 0 0 0 0 0 0 0 Q15572 TAF1C_HUMAN TATA box-binding protein-associated factor RNA polymerase I subunit C (RNA polymerase I-specific TBP-associated factor 110 kDa) (TAFI110) (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (Transcription initiation factor SL1/TIF-IB subunit C) TAF1C Homo sapiens (Human) transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription initiation at RNA polymerase I promoter [GO:0006361] fibrillar center [GO:0001650]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; RNA polymerase transcription factor SL1 complex [GO:0005668] RNA polymerase I core promoter sequence-specific DNA binding [GO:0001164]; RNA polymerase I general transcription initiation factor activity [GO:0001181] 0.96997 -4.2969 DLLFRGGCR 10.1536 10.2377 0 0 0 0 0 9.92345 0 0 0 0 0 0 0 0 9.37623 0 0 0 0 0 0 10.0081 10.0509 0 0 Q15582 BGH3_HUMAN Transforming growth factor-beta-induced protein ig-h3 (Beta ig-h3) (Kerato-epithelin) (RGD-containing collagen-associated protein) (RGD-CAP) TGFBI BIGH3 Homo sapiens (Human) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; chondrocyte differentiation [GO:0002062]; extracellular matrix organization [GO:0030198]; localization [GO:0051179]; negative regulation of cell adhesion [GO:0007162]; response to stimulus [GO:0050896]; visual perception [GO:0007601] basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802] cell adhesion molecule binding [GO:0050839]; collagen binding [GO:0005518]; extracellular matrix binding [GO:0050840]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178] 0.23621 0.85128 EGVYTVFAPTNEAFR 10.4261 0 0 0 0 0 0 9.07911 0 0 0 9.54705 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15583 TGIF1_HUMAN Homeobox protein TGIF1 (5'-TG-3'-interacting factor 1) TGIF1 TGIF Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] chromatin [GO:0000785]; nucleoplasm [GO:0005654] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.73145 0.33722 ALSPELGTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.08738 0 0 0 10.6994 0 0 Q15596 NCOA2_HUMAN Nuclear receptor coactivator 2 (NCoA-2) (Class E basic helix-loop-helix protein 75) (bHLHe75) (Transcriptional intermediary factor 2) (hTIF2) NCOA2 BHLHE75 SRC2 TIF2 Homo sapiens (Human) cellular response to hormone stimulus [GO:0032870]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; circadian regulation of gene expression [GO:0032922]; locomotor rhythm [GO:0045475]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cellular response to insulin stimulus [GO:1900076]; regulation of DNA-templated transcription [GO:0006355]; regulation of glucose metabolic process [GO:0010906]; regulation of lipid metabolic process [GO:0019216]; response to progesterone [GO:0032570] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; RNA polymerase II transcription regulator complex [GO:0090575]; transcription regulator complex [GO:0005667] aryl hydrocarbon receptor binding [GO:0017162]; chromatin binding [GO:0003682]; nuclear receptor binding [GO:0016922]; nuclear receptor coactivator activity [GO:0030374]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding [GO:0001162]; transcription coactivator activity [GO:0003713] 0.91357 -0.75351 DIGLPEITPK 0 9.17203 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q155Q3 DIXC1_HUMAN Dixin (Coiled-coil protein DIX1) (Coiled-coil-DIX1) (DIX domain-containing protein 1) DIXDC1 CCD1 KIAA1735 Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; cerebellar cortex development [GO:0021695]; cerebral cortex radially oriented cell migration [GO:0021799]; forebrain ventricular zone progenitor cell division [GO:0021869]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of axonogenesis [GO:0050772]; positive regulation of JNK cascade [GO:0046330]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of microtubule cytoskeleton organization [GO:0070507] axon terminus [GO:0043679]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; neuronal cell body [GO:0043025]; protein-containing complex [GO:0032991] actin binding [GO:0003779]; gamma-tubulin binding [GO:0043015]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein domain specific binding [GO:0019904] 0.92394 -1.0465 EGNHRYHFK 0 0 0 0 0 0 10.2566 0 10.1022 0 9.94623 0 0 0 0 0 0 0 0 0 0 0 9.51304 9.67354 0 10.9901 0 Q15615 OR4D1_HUMAN Olfactory receptor 4D1 (Olfactory receptor 4D3) (Olfactory receptor TPCR16) OR4D1 OR4D3 Homo sapiens (Human) sensory perception of smell [GO:0007608] membrane [GO:0016020]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.91514 -0.77076 CLVICRE 0 0 0 0 0 0 0 0 0 0 11.3528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15628 TRADD_HUMAN Tumor necrosis factor receptor type 1-associated DEATH domain protein (TNFR1-associated DEATH domain protein) (TNFRSF1A-associated via death domain) TRADD Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to tumor necrosis factor [GO:0071356]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of hair follicle development [GO:0051798]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209] cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; tumor necrosis factor receptor superfamily complex [GO:0002947] death domain binding [GO:0070513]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; molecular adaptor activity [GO:0060090]; protein-containing complex binding [GO:0044877]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]; tumor necrosis factor receptor binding [GO:0005164] 0.96954 -4.9563 AYREGALRAALQR 9.6057 0 0 9.7061 0 0 0 0 0 0 0 0 0 0 0 14.3463 0 0 0 0 9.7775 0 0 0 0 0 0 Q15631 TSN_HUMAN Translin (EC 3.1.-.-) (Component 3 of promoter of RISC) (C3PO) TSN Homo sapiens (Human) DNA recombination [GO:0006310]; siRNA processing [GO:0030422] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoribonuclease complex [GO:1902555]; male germ cell nucleus [GO:0001673]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; sequence-specific DNA binding [GO:0043565]; single-stranded DNA binding [GO:0003697] 0.81265 0.22413 ETAAACVEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.9263 0 0 0 0 0 0 Q15637 SF01_HUMAN Splicing factor 1 (Mammalian branch point-binding protein) (BBP) (mBBP) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Zinc finger protein 162) SF1 ZFM1 ZNF162 Homo sapiens (Human) "Leydig cell differentiation [GO:0033327]; male sex determination [GO:0030238]; mRNA 3'-splice site recognition [GO:0000389]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of smooth muscle cell proliferation [GO:0048662]; nuclear body organization [GO:0030575]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of steroid biosynthetic process [GO:0050810]; spliceosomal complex assembly [GO:0000245]" nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribosome [GO:0005840]; spliceosomal complex [GO:0005681]; U2AF complex [GO:0089701] identical protein binding [GO:0042802]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714]; zinc ion binding [GO:0008270] 0.93244 -1.2638 LNGTLREDDNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.41973 0 11.3862 10.762 10.8072 Q15643 TRIPB_HUMAN Thyroid receptor-interacting protein 11 (TR-interacting protein 11) (TRIP-11) (Clonal evolution-related gene on chromosome 14 protein) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) TRIP11 CEV14 Homo sapiens (Human) cartilage development [GO:0051216]; chondrocyte differentiation involved in endochondral bone morphogenesis [GO:0003413]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; Golgi ribbon formation [GO:0090161]; inner ear receptor cell stereocilium organization [GO:0060122]; protein glycosylation [GO:0006486]; transcription by RNA polymerase II [GO:0006366]; ventricular septum development [GO:0003281]; vesicle tethering to Golgi [GO:0099041] cis-Golgi network [GO:0005801]; cytoskeleton [GO:0005856]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; inner acrosomal membrane [GO:0002079]; outer acrosomal membrane [GO:0002081]; transport vesicle [GO:0030133] small GTPase binding [GO:0031267]; transcription coactivator activity [GO:0003713] 0.96936 -7.1751 DINKKLSSAENDR 0 0 0 0 0 9.13645 0 9.96042 0 0 8.90929 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3426 9.36623 0 Q15645 PCH2_HUMAN Pachytene checkpoint protein 2 homolog (Human papillomavirus type 16 E1 protein-binding protein) (16E1-BP) (HPV16 E1 protein-binding protein) (Thyroid hormone receptor interactor 13) (Thyroid receptor-interacting protein 13) (TR-interacting protein 13) (TRIP-13) TRIP13 PCH2 Homo sapiens (Human) double-strand break repair [GO:0006302]; female meiosis I [GO:0007144]; male meiosis I [GO:0007141]; meiotic recombination checkpoint signaling [GO:0051598]; mitotic spindle assembly checkpoint signaling [GO:0007094]; oocyte maturation [GO:0001556]; oogenesis [GO:0048477]; reciprocal meiotic recombination [GO:0007131]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130]; transcription by RNA polymerase II [GO:0006366] chromosome [GO:0005694]; male germ cell nucleus [GO:0001673]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; identical protein binding [GO:0042802]; transcription coregulator activity [GO:0003712] 0.95387 -1.525 TSLCKALAQK 0 0 0 0 0 0 0 8.81173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15646 OASL_HUMAN 2'-5'-oligoadenylate synthase-like protein (2'-5'-OAS-related protein) (2'-5'-OAS-RP) (59 kDa 2'-5'-oligoadenylate synthase-like protein) (Thyroid receptor-interacting protein 14) (TR-interacting protein 14) (TRIP-14) (p59 OASL) (p59OASL) OASL TRIP14 Homo sapiens (Human) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; interleukin-27-mediated signaling pathway [GO:0070106]; negative regulation of viral genome replication [GO:0045071]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of ribonuclease activity [GO:0060700]; response to virus [GO:0009615] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] DNA binding [GO:0003677]; double-stranded RNA binding [GO:0003725]; nuclear thyroid hormone receptor binding [GO:0046966]; nucleotidyltransferase activity [GO:0016779]; RNA binding [GO:0003723] 0.96781 -3.6736 KGEALFPAS 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.45251 Q15648 MED1_HUMAN Mediator of RNA polymerase II transcription subunit 1 (Activator-recruited cofactor 205 kDa component) (ARC205) (Mediator complex subunit 1) (Peroxisome proliferator-activated receptor-binding protein) (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TR-interacting protein 2) (TRIP-2) (Vitamin D receptor-interacting protein complex component DRIP205) (p53 regulatory protein RB18A) MED1 ARC205 CRSP1 CRSP200 DRIP205 DRIP230 PBP PPARBP PPARGBP RB18A TRAP220 TRIP2 Homo sapiens (Human) androgen biosynthetic process [GO:0006702]; angiogenesis [GO:0001525]; animal organ regeneration [GO:0031100]; brain development [GO:0007420]; cell morphogenesis [GO:0000902]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to steroid hormone stimulus [GO:0071383]; cellular response to thyroid hormone stimulus [GO:0097067]; embryonic heart tube development [GO:0035050]; embryonic hemopoiesis [GO:0035162]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic placenta development [GO:0001892]; enucleate erythrocyte development [GO:0048822]; epithelial cell proliferation involved in mammary gland duct elongation [GO:0060750]; erythrocyte development [GO:0048821]; fat cell differentiation [GO:0045444]; G0 to G1 transition [GO:0045023]; hematopoietic stem cell differentiation [GO:0060218]; intracellular steroid hormone receptor signaling pathway [GO:0030518]; keratinocyte differentiation [GO:0030216]; lactation [GO:0007595]; lens development in camera-type eye [GO:0002088]; liver development [GO:0001889]; mammary gland branching involved in pregnancy [GO:0060745]; mammary gland branching involved in thelarche [GO:0060744]; megakaryocyte development [GO:0035855]; monocyte differentiation [GO:0030224]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of G0 to G1 transition [GO:0070318]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; protein import into nucleus [GO:0006606]; regulation of RNA biosynthetic process [GO:2001141]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of vitamin D receptor signaling pathway [GO:0070562]; retinal pigment epithelium development [GO:0003406]; RNA polymerase II preinitiation complex assembly [GO:0051123]; thyroid hormone generation [GO:0006590]; thyroid hormone mediated signaling pathway [GO:0002154]; ventricular trabecula myocardium morphogenesis [GO:0003222] core mediator complex [GO:0070847]; mediator complex [GO:0016592]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor binding [GO:0140297]; LBD domain binding [GO:0050693]; nuclear estrogen receptor binding [GO:0030331]; nuclear receptor binding [GO:0016922]; nuclear receptor coactivator activity [GO:0030374]; nuclear retinoic acid receptor binding [GO:0042974]; nuclear thyroid hormone receptor binding [GO:0046966]; nuclear vitamin D receptor binding [GO:0042809]; peroxisome proliferator activated receptor binding [GO:0042975]; promoter-specific chromatin binding [GO:1990841]; protein-containing complex binding [GO:0044877]; transcription coactivator activity [GO:0003713]; transcription coactivator binding [GO:0001223]; transcription coregulator activity [GO:0003712]; transcription corepressor activity [GO:0003714] 0.92352 -1.0705 GSPSHSK 0 0 0 0 13.3366 0 17.1666 10.2244 0 0 0 11.4064 16.7787 0 0 0 0 0 0 0 12.314 9.26751 0 0 0 0 0 Q15650 TRIP4_HUMAN Activating signal cointegrator 1 (ASC-1) (Thyroid receptor-interacting protein 4) (TR-interacting protein 4) (TRIP-4) TRIP4 RQT4 Homo sapiens (Human) intracellular estrogen receptor signaling pathway [GO:0030520]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription [GO:0006355]; regulation of myoblast differentiation [GO:0045661]; rescue of stalled ribosome [GO:0072344]; ribosome disassembly [GO:0032790]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116]; toxin transport [GO:1901998] activating signal cointegrator 1 complex [GO:0099053]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; microtubule organizing center [GO:0005815]; neuromuscular junction [GO:0031594]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] histone acetyltransferase binding [GO:0035035]; nuclear estrogen receptor binding [GO:0030331]; nuclear receptor binding [GO:0016922]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; transcription coactivator activity [GO:0003713]; ubiquitin-like protein ligase binding [GO:0044389]; zinc ion binding [GO:0008270] 0.76768 0.2775 DLLPHQELR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5287 0 Q15651 HMGN3_HUMAN High mobility group nucleosome-binding domain-containing protein 3 (Thyroid receptor-interacting protein 7) (TR-interacting protein 7) (TRIP-7) HMGN3 TRIP7 PNAS-24 Homo sapiens (Human) chromatin organization [GO:0006325] chromatin [GO:0000785]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; nuclear thyroid hormone receptor binding [GO:0046966]; nucleosomal DNA binding [GO:0031492] 0.9631 -2.6363 SPENTEGKDGSKVTK 12.3488 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15652 JHD2C_HUMAN Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TR-interacting protein 8) (TRIP-8) JMJD1C JHDM2C KIAA1380 TRIP8 Homo sapiens (Human) blood coagulation [GO:0007596]; histone H3-K9 demethylation [GO:0033169]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654] chromatin DNA binding [GO:0031490]; dioxygenase activity [GO:0051213]; histone H3K9 demethylase activity [GO:0032454]; metal ion binding [GO:0046872]; nuclear thyroid hormone receptor binding [GO:0046966]; transcription coregulator activity [GO:0003712] 0.96895 -7.0727 AVSHRDSR 0 9.44779 0 0 10.8466 0 11.2051 9.00854 0 11.1942 10.4755 0 0 0 10.6157 10.9936 0 0 10.0637 0 0 0 0 0 0 0 0 Q15653 IKBB_HUMAN NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkB-B) (IkB-beta) (IkappaBbeta) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9) (TRIP-9) NFKBIB IKBB TRIP9 Homo sapiens (Human) cellular response to lipopolysaccharide [GO:0071222]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; DNA-templated transcription [GO:0006351]; inflammatory response [GO:0006954]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; signal transduction [GO:0007165] cytosol [GO:0005829]; nucleus [GO:0005634] transcription coactivator activity [GO:0003713] 0.8854 -0.29155 AGANPAARMYGGR 0 0 0 0 0 0 0 0 0 0 0 9.37099 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15654 TRIP6_HUMAN Thyroid receptor-interacting protein 6 (TR-interacting protein 6) (TRIP-6) (Opa-interacting protein 1) (OIP-1) (Zyxin-related protein 1) (ZRP-1) TRIP6 OIP1 Homo sapiens (Human) chordate embryonic development [GO:0043009]; focal adhesion assembly [GO:0048041]; positive regulation of cell migration [GO:0030335]; positive regulation of NIK/NF-kappaB signaling [GO:1901224] cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; plasma membrane [GO:0005886] interleukin-1 receptor binding [GO:0005149]; kinase binding [GO:0019900]; metal ion binding [GO:0046872]; nuclear thyroid hormone receptor binding [GO:0046966]; RNA binding [GO:0003723] 0.87198 0.035095 EEAAGVSGPAGR 0 0 0 0 0 0 0 0 0 0 0 0 9.75826 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15669 RHOH_HUMAN Rho-related GTP-binding protein RhoH (GTP-binding protein TTF) (Translocation three four protein) RHOH ARHH TTF Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell migration [GO:0016477]; mast cell activation [GO:0045576]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; positive regulation of T cell differentiation [GO:0045582]; regulation of DNA-templated transcription [GO:0006355]; small GTPase mediated signal transduction [GO:0007264]; T cell differentiation [GO:0030217] cytoplasm [GO:0005737]; immunological synapse [GO:0001772]; plasma membrane [GO:0005886] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; GTPase inhibitor activity [GO:0005095]; kinase inhibitor activity [GO:0019210]; small GTPase binding [GO:0031267] 0.95458 -1.5086 GVQQVFECAVRTAVNQAR 0 0 0 0 0 10.0038 8.86861 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15678 PTN14_HUMAN Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez) PTPN14 PEZ PTPD2 Homo sapiens (Human) lymphangiogenesis [GO:0001946]; negative regulation of cell population proliferation [GO:0008285]; protein dephosphorylation [GO:0006470]; regulation of protein export from nucleus [GO:0046825] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; transcription coregulator activity [GO:0003712] 0.96837 -3.6127 FKVTTKFR 0 0 0 0 0 0 0 0 0 0 0 0 8.9857 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15696 U2AFM_HUMAN "U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (Renal carcinoma antigen NY-REN-20) (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (U2AF35-related protein) (URP)" ZRSR2 U2AF1-RS2 U2AF1L2 U2AF1RS2 URP Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245]" nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U12-type spliceosomal complex [GO:0005689]; U2AF complex [GO:0089701] identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; pre-mRNA 3'-splice site binding [GO:0030628] 0.67149 0.39371 TGSSFGK 0 0 0 0 0 0 9.26101 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15697 ZN174_HUMAN Zinc finger protein 174 (AW-1) (Zinc finger and SCAN domain-containing protein 8) ZNF174 ZSCAN8 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; fibrillar center [GO:0001650]; nuclear body [GO:0016604]; nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]" 0.88168 -0.30667 NCPDPELCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.54722 0 0 0 0 Q15699 ALX1_HUMAN ALX homeobox protein 1 (Cartilage homeoprotein 1) (CART-1) ALX1 CART1 Homo sapiens (Human) embryonic skeletal system morphogenesis [GO:0048704]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of transcription by RNA polymerase II [GO:0045944] chromatin [GO:0000785]; Golgi apparatus [GO:0005794]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96289 -2.0918 AEHHVRLER 0 0 0 0 0 0 0 0 0 0 0 9.6079 9.26501 0 0 0 0 0 0 0 0 0 10.8717 0 0 10.5533 0 Q15700 DLG2_HUMAN Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93) DLG2 Homo sapiens (Human) anterograde axonal protein transport [GO:0099641]; cellular response to potassium ion [GO:0035865]; chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; retrograde axonal protein transport [GO:0099642] adherens junction [GO:0005912]; axon cytoplasm [GO:1904115]; cytosol [GO:0005829]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839] guanylate kinase activity [GO:0004385]; kinase binding [GO:0019900] 0.96387 -2.1082 DYEVDGRDYHFVISREQMEK 0 0 10.4681 0 0 0 0 10.9636 0 8.96619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.25904 0 0 Q15714 T22D1_HUMAN TSC22 domain family protein 1 (Cerebral protein 2) (Regulatory protein TSC-22) (TGFB-stimulated clone 22 homolog) (Transforming growth factor beta-1-induced transcript 4 protein) TSC22D1 KIAA1994 TGFB1I4 TSC22 hucep-2 Homo sapiens (Human) negative regulation of apoptotic process [GO:0043066]; positive regulation of cell population proliferation [GO:0008284]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] cytosol [GO:0005829]; nucleus [GO:0005634] 0.91466 -0.78223 LDSSSEPFKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5227 0 0 0 0 0 0 0 Q15717 ELAV1_HUMAN ELAV-like protein 1 (Hu-antigen R) (HuR) ELAVL1 HUR Homo sapiens (Human) 3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA stabilization [GO:0048255]; negative regulation of miRNA-mediated gene silencing [GO:0060965]; positive regulation of translation [GO:0045727]; post-transcriptional gene silencing [GO:0016441]; protein homooligomerization [GO:0051260]; protein import into nucleus [GO:0006606]; regulation of stem cell population maintenance [GO:2000036] cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]; sarcoplasm [GO:0016528] double-stranded RNA binding [GO:0003725]; lncRNA binding [GO:0106222]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723] 0.021028 1.6417 AINTLNGLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1472 0 0 0 0 0 0 10.0607 9.73203 10.2064 Q15726 KISS1_HUMAN Metastasis-suppressor KiSS-1 (Kisspeptin-1) [Cleaved into: Metastin (Kisspeptin-54); Kisspeptin-14; Kisspeptin-13; Kisspeptin-10] KISS1 PP5098 Homo sapiens (Human) cytoskeleton organization [GO:0007010]; G protein-coupled receptor signaling pathway [GO:0007186]; generation of ovulation cycle rhythm [GO:0060112]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of growth hormone secretion [GO:0060124]; positive regulation of luteinizing hormone secretion [GO:0033686]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of synaptic transmission [GO:0050806] apical plasma membrane [GO:0016324]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025] kisspeptin receptor binding [GO:0031773] 0.43023 0.65954 DLPNYNWNSFGLR 0 0 0 0 0 10.2025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15735 PI5PA_HUMAN "Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.36) (Inositol polyphosphate 5-phosphatase J) (Phosphatidylinositol 1,3,4,5-tetrakisphosphate 5-phosphatase) (EC 3.1.3.56) (Phosphatidylinositol 1,4,5-trisphosphate 5-phosphatase) (EC 3.1.3.56)" INPP5J PIB5PA PIPP Homo sapiens (Human) inositol phosphate metabolic process [GO:0043647]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of neuron projection development [GO:0010977]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856] cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; growth cone [GO:0030426]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; ruffle membrane [GO:0032587] "inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity [GO:0052659]; inositol-1,4,5-trisphosphate 5-phosphatase activity [GO:0052658]; inositol-polyphosphate 5-phosphatase activity [GO:0004445]; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity [GO:0034485]; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity [GO:0004439]; SH3 domain binding [GO:0017124]" 0.94905 -1.3791 SPSPQSR 0 0 0 0 0 0 9.15507 0 0 10.3222 0 0 0 7.60259 0 0 0 10.45 0 0 0 0 0 0 0 0 0 Q15738 NSDHL_HUMAN "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (EC 1.1.1.170) (Protein H105e3)" NSDHL H105E3 Homo sapiens (Human) cholesterol biosynthetic process [GO:0006695]; cholesterol metabolic process [GO:0008203]; hair follicle development [GO:0001942]; labyrinthine layer blood vessel development [GO:0060716]; smoothened signaling pathway [GO:0007224] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; lipid droplet [GO:0005811] "3-beta-hydroxy-delta5-steroid dehydrogenase activity [GO:0003854]; 3-beta-hydroxysteroid dehydrogenase/C4-decarboxylase activity [GO:0102175]; 4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-oxidoreductase (decarboxylating) activity [GO:0103066]; 4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-dehydrogenase (decarboxylating) activity [GO:0103067]; C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity [GO:0000252]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity [GO:0047012]" 0.96921 -3.0683 FVIGNGK 0 0 0 0 0 0 0 0 0 0 9.31436 0 9.44149 0 9.7627 0 0 0 0 0 0 0 0 0 0 0 0 Q15742 NAB2_HUMAN NGFI-A-binding protein 2 (EGR-1-binding protein 2) (Melanoma-associated delayed early response protein) (Protein MADER) NAB2 MADER Homo sapiens (Human) endochondral ossification [GO:0001958]; myelination [GO:0042552]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of tau-protein kinase activity [GO:1902949]; regulation of DNA-templated transcription [GO:0006355]; regulation of epidermis development [GO:0045682]; Schwann cell differentiation [GO:0014037] nucleoplasm [GO:0005654]; nucleus [GO:0005634] identical protein binding [GO:0042802]; transcription coregulator activity [GO:0003712]; transcription corepressor activity [GO:0003714] 0.93994 -1.3062 KYSIIYGRFDSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.486 0 0 0 0 0 0 0 0 Q15743 OGR1_HUMAN Ovarian cancer G-protein coupled receptor 1 (OGR-1) (G-protein coupled receptor 68) (GPR12A) (Sphingosylphosphorylcholine receptor) GPR68 OGR1 Homo sapiens (Human) cellular response to pH [GO:0071467]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; monocyte differentiation [GO:0030224]; negative regulation of monocyte differentiation [GO:0045656]; osteoclast development [GO:0036035]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of osteoclast development [GO:2001206] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930] 0.91678 -0.84593 RSHGTQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.87662 0 0 0 0 0 0 0 0 0 0 Q15746 MYLK_HUMAN "Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]" MYLK MLCK MLCK1 MYLK1 Homo sapiens (Human) aorta smooth muscle tissue morphogenesis [GO:0060414]; bleb assembly [GO:0032060]; cellular hypotonic response [GO:0071476]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell migration [GO:0030335]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; smooth muscle contraction [GO:0006939]; tonic smooth muscle contraction [GO:0014820] actin cytoskeleton [GO:0015629]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886]; stress fiber [GO:0001725] actin binding [GO:0003779]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; myosin light chain kinase activity [GO:0004687] 0.88502 -0.23316 AGESVELFGK 0 0 0 0 0 0 0 0 0 9.62385 0 9.97714 0 0 0 0 10.3825 0 8.95899 0 0 0 0 0 0 9.68505 0 Q15751 HERC1_HUMAN Probable E3 ubiquitin-protein ligase HERC1 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 1) (HECT-type E3 ubiquitin transferase HERC1) (p532) (p619) HERC1 Homo sapiens (Human) autophagy [GO:0006914]; cerebellar Purkinje cell differentiation [GO:0021702]; corpus callosum development [GO:0022038]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; protein ubiquitination [GO:0016567] cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; membrane [GO:0016020] guanyl-nucleotide exchange factor activity [GO:0005085]; ubiquitin-protein transferase activity [GO:0004842] 0.96923 -4.1774 AVMRSPIK 0 0 9.39034 0 0 0 0 0 9.77717 0 0 0 0 0 0 0 0 0 8.74012 7.47865 10.7639 0 0 8.85776 12.1954 0 0 Q15760 GPR19_HUMAN Probable G-protein coupled receptor 19 (GPR-NGA) GPR19 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186] cilium [GO:0005929]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930] 0.96227 -2.5149 TMNIVPRTK 0 0 0 0 0 0 0 0 0 0 0 0 10.625 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15772 SPEG_HUMAN Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1) SPEG APEG1 KIAA1297 Homo sapiens (Human) muscle cell differentiation [GO:0042692]; muscle organ development [GO:0007517]; negative regulation of cell population proliferation [GO:0008285]; protein phosphorylation [GO:0006468] nucleus [GO:0005634] ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96893 -7.5606 AEAATRHKVLLR 9.41327 9.53904 9.33575 0 0 0 0 0 0 9.51918 0 11.3111 8.67899 11.0005 9.82985 0 0 0 0 0 0 0 0 9.25906 0 0 0 Q15776 ZKSC8_HUMAN Zinc finger protein with KRAB and SCAN domains 8 (LD5-1) (Zinc finger protein 192) ZKSCAN8 ZNF192 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96276 -2.6729 GLEHEEARDLLGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.50512 0 0 0 0 0 0 0 0 0 0 0 0 Q15782 CH3L2_HUMAN Chitinase-3-like protein 2 (Chondrocyte protein 39) (YKL-39) CHI3L2 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; chitin catabolic process [GO:0006032] extracellular region [GO:0005576]; extracellular space [GO:0005615] carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; hydrolase activity [GO:0016787] 0.84925 0.11361 NHNFDGLDVSWIYPDQK 0 0 0 0 0 0 8.93699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15785 TOM34_HUMAN Mitochondrial import receptor subunit TOM34 (hTom34) (Translocase of outer membrane 34 kDa subunit) TOMM34 URCC3 Homo sapiens (Human) protein targeting to mitochondrion [GO:0006626] cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleus [GO:0005634] heat shock protein binding [GO:0031072] 0.81808 0.2198 FPDSVEELR 0 0 0 0 0 0 0 0 0 0 0 0 8.66754 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15788 NCOA1_HUMAN Nuclear receptor coactivator 1 (NCoA-1) (EC 2.3.1.48) (Class E basic helix-loop-helix protein 74) (bHLHe74) (Protein Hin-2) (RIP160) (Renal carcinoma antigen NY-REN-52) (Steroid receptor coactivator 1) (SRC-1) NCOA1 BHLHE74 SRC1 Homo sapiens (Human) cellular response to hormone stimulus [GO:0032870]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; labyrinthine layer morphogenesis [GO:0060713]; mRNA transcription by RNA polymerase II [GO:0042789]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter by galactose [GO:0000435]; regulation of cellular response to insulin stimulus [GO:1900076]; regulation of thyroid hormone mediated signaling pathway [GO:0002155] chromatin [GO:0000785]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; RNA polymerase II transcription regulator complex [GO:0090575]; transcription regulator complex [GO:0005667] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; histone acetyltransferase activity [GO:0004402]; nuclear estrogen receptor binding [GO:0030331]; nuclear receptor binding [GO:0016922]; nuclear receptor coactivator activity [GO:0030374]; protein dimerization activity [GO:0046983]; transcription coactivator activity [GO:0003713] 0.3495 0.7647 DSASTSVSVTGQVQGNSSIKLELDASK 0 0 0 0 0 0 8.66007 8.84273 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15811 ITSN1_HUMAN Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17) ITSN1 ITSN SH3D1A Homo sapiens (Human) clathrin-dependent synaptic vesicle endocytosis [GO:0150007]; endosomal transport [GO:0016197]; exocytosis [GO:0006887]; intracellular signal transduction [GO:0035556]; protein localization [GO:0008104]; protein transport [GO:0015031]; regulation of small GTPase mediated signal transduction [GO:0051056] clathrin-coated pit [GO:0005905]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular vesicle [GO:0097708]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; recycling endosome [GO:0055037] calcium ion binding [GO:0005509]; guanyl-nucleotide exchange factor activity [GO:0005085]; molecular adaptor activity [GO:0060090]; proline-rich region binding [GO:0070064] 0.95511 -1.5624 KDGDWWTGTVGDKAGVFPSNYVR 0 0 0 0 0 0 10.6205 8.93381 12.5243 0 11.9694 0 11.3985 0 0 0 8.69572 11.3365 0 0 0 0 0 0 0 0 0 Q15814 TBCC_HUMAN Tubulin-specific chaperone C (Tubulin-folding cofactor C) (CFC) TBCC Homo sapiens (Human) post-chaperonin tubulin folding pathway [GO:0007023]; protein folding [GO:0006457]; tubulin complex assembly [GO:0007021] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; microtubule [GO:0005874]; photoreceptor connecting cilium [GO:0032391] GTPase activity [GO:0003924]; protein-folding chaperone binding [GO:0051087]; tubulin binding [GO:0015631] 0.61204 0.42028 DLSLVPER 0 0 0 0 0 0 0 0 9.76939 0 0 0 0 0 0 0 0 0 0 10.0334 0 0 0 0 0 0 0 Q15822 ACHA2_HUMAN Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 Homo sapiens (Human) cellular response to nicotine [GO:0071316]; chemical synaptic transmission [GO:0007268]; membrane depolarization [GO:0051899]; modulation of inhibitory postsynaptic potential [GO:0098828]; monoatomic ion transmembrane transport [GO:0034220]; monoatomic ion transport [GO:0006811]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to acetylcholine [GO:1905144]; signal transduction [GO:0007165] acetylcholine-gated channel complex [GO:0005892]; intercellular bridge [GO:0045171]; membrane [GO:0016020]; neuron projection cytoplasm [GO:0120111]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202] acetylcholine receptor activity [GO:0015464]; acetylcholine-gated monoatomic cation-selective channel activity [GO:0022848]; heterocyclic compound binding [GO:1901363]; quaternary ammonium group binding [GO:0050997] 0.92943 -1.2298 IDLEQMEQTVDLK 0 0 0 0 0 0 0 0 0 0 0 0 10.6837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15825 ACHA6_HUMAN Neuronal acetylcholine receptor subunit alpha-6 CHRNA6 Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; membrane depolarization [GO:0051899]; monoatomic ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of dopamine secretion [GO:0014059]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] acetylcholine-gated channel complex [GO:0005892]; dopaminergic synapse [GO:0098691]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202] acetylcholine receptor activity [GO:0015464]; acetylcholine-gated monoatomic cation-selective channel activity [GO:0022848] 0.39839 0.70659 VDMNDFWENSEWEIIDASGYK 0 9.3437 0 0 0 0 0 9.42652 9.22168 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15833 STXB2_HUMAN Syntaxin-binding protein 2 (Protein unc-18 homolog 2) (Unc18-2) (Protein unc-18 homolog B) (Unc-18B) STXBP2 UNC18B Homo sapiens (Human) cellular response to type II interferon [GO:0071346]; intracellular protein transport [GO:0006886]; leukocyte mediated cytotoxicity [GO:0001909]; neurotransmitter secretion [GO:0007269]; neutrophil degranulation [GO:0043312]; regulation of mast cell degranulation [GO:0043304]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192] apical plasma membrane [GO:0016324]; azurophil granule [GO:0042582]; cytolytic granule [GO:0044194]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; secretory granule [GO:0030141]; specific granule [GO:0042581]; tertiary granule [GO:0070820]; zymogen granule membrane [GO:0042589] syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348] 0.92235 -1.0959 FLDDLKALDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.98641 0 0 0 10.2997 0 0 0 Q15836 VAMP3_HUMAN Vesicle-associated membrane protein 3 (VAMP-3) (Cellubrevin) (CEB) (Synaptobrevin-3) VAMP3 SYB3 Homo sapiens (Human) "calcium-ion regulated exocytosis [GO:0017156]; cellular response to type II interferon [GO:0071346]; exocytosis [GO:0006887]; Golgi to plasma membrane protein transport [GO:0043001]; membrane fusion [GO:0061025]; negative regulation of secretion by cell [GO:1903531]; positive regulation of receptor recycling [GO:0001921]; protein-containing complex assembly [GO:0065003]; retrograde transport, endosome to Golgi [GO:0042147]; SNARE complex assembly [GO:0035493]; substrate adhesion-dependent cell spreading [GO:0034446]; vesicle docking involved in exocytosis [GO:0006904]; vesicle fusion [GO:0006906]; vesicle-mediated transport [GO:0016192]" cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; clathrin-coated vesicle [GO:0030136]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; secretory granule [GO:0030141]; SNARE complex [GO:0031201]; synapse [GO:0045202]; trans-Golgi network membrane [GO:0032588]; transport vesicle [GO:0030133] SNAP receptor activity [GO:0005484]; syntaxin-1 binding [GO:0017075] 0.92364 -1.0703 LQQTQNQVDEVVDIMR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.6669 0 0 0 0 Q15842 KCNJ8_HUMAN "ATP-sensitive inward rectifier potassium channel 8 (Inward rectifier K(+) channel Kir6.1) (Potassium channel, inwardly rectifying subfamily J member 8) (uKATP-1)" KCNJ8 Homo sapiens (Human) defense response to virus [GO:0051607]; heart development [GO:0007507]; inorganic cation transmembrane transport [GO:0098662]; kidney development [GO:0001822]; membrane repolarization during ventricular cardiac muscle cell action potential [GO:0098915]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of monoatomic ion transmembrane transport [GO:0034765]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; transport across blood-brain barrier [GO:0150104] glutamatergic synapse [GO:0098978]; inward rectifying potassium channel [GO:0008282]; mitochondrion [GO:0005739]; myofibril [GO:0030016]; plasma membrane [GO:0005886]; potassium ion-transporting ATPase complex [GO:0031004]; presynaptic active zone membrane [GO:0048787]; sarcolemma [GO:0042383]; voltage-gated potassium channel complex [GO:0008076] ATP binding [GO:0005524]; ATP-activated inward rectifier potassium channel activity [GO:0015272]; ATPase-coupled monoatomic cation transmembrane transporter activity [GO:0019829]; inward rectifier potassium channel activity [GO:0005242]; sulfonylurea receptor binding [GO:0017098]; voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential [GO:0099508]; voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1902282] 0.89046 -0.4659 TAQAHRR 0 0 0 0 0 0 10.7008 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.00694 0 Q15849 UT2_HUMAN "Urea transporter 2 (Solute carrier family 14 member 2) (Urea transporter, kidney)" SLC14A2 HUT2 UT2 Homo sapiens (Human) transmembrane transport [GO:0055085]; urea transmembrane transport [GO:0071918]; urea transport [GO:0015840] apical plasma membrane [GO:0016324]; membrane [GO:0016020]; plasma membrane [GO:0005886] cell adhesion molecule binding [GO:0050839]; urea transmembrane transporter activity [GO:0015204] 0.96989 -4.2991 IEKLNER 0 0 0 0 0 0 0 0 0 0 0 0 10.4555 0 0 0 9.19542 0 0 0 0 0 0 0 10.4255 0 10.0622 Q15858 SCN9A_HUMAN Sodium channel protein type 9 subunit alpha (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1) (PN1) (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) SCN9A NENA Homo sapiens (Human) behavioral response to formalin induced pain [GO:0061368]; calcium ion import across plasma membrane [GO:0098703]; circadian rhythm [GO:0007623]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; inflammatory response [GO:0006954]; negative regulation of action potential [GO:0045759]; neuronal action potential [GO:0019228]; post-embryonic development [GO:0009791]; regulation of monoatomic ion transmembrane transport [GO:0034765]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] axon [GO:0030424]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; voltage-gated sodium channel complex [GO:0001518] high voltage-gated calcium channel activity [GO:0008331]; sodium ion binding [GO:0031402]; voltage-gated sodium channel activity [GO:0005248] 0.84106 0.14673 LMTQDYWENLYQQTLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1411 0 0 0 0 0 0 0 0 0 0 0 Q15878 CAC1E_HUMAN "Voltage-dependent R-type calcium channel subunit alpha-1E (Brain calcium channel II) (BII) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Voltage-gated calcium channel subunit alpha Cav2.3)" CACNA1E CACH6 CACNL1A6 Homo sapiens (Human) calcium ion import across plasma membrane [GO:0098703]; chemical synaptic transmission [GO:0007268]; regulation of monoatomic ion transmembrane transport [GO:0034765] neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; synapse [GO:0045202]; voltage-gated calcium channel complex [GO:0005891] calcium ion binding [GO:0005509]; high voltage-gated calcium channel activity [GO:0008331]; voltage-gated calcium channel activity [GO:0005245]; voltage-gated monoatomic cation channel activity [GO:0022843] 0.96769 -2.9943 DEQEEEEAFNQK 12.9691 12.804 12.9099 11.3739 0 0 12.7389 12.6914 0 0 13.3625 0 9.4006 0 9.14458 0 10.7696 0 0 0 0 0 0 0 0 0 0 Q15906 VPS72_HUMAN Vacuolar protein sorting-associated protein 72 homolog (Protein YL-1) (Transcription factor-like 1) VPS72 TCFL1 YL1 Homo sapiens (Human) histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of DNA-templated transcription [GO:0006355]; regulation of double-strand break repair [GO:2000779]; somatic stem cell population maintenance [GO:0035019]; transcription initiation-coupled chromatin remodeling [GO:0045815] NuA4 histone acetyltransferase complex [GO:0035267]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] ATP-dependent H2AZ histone chaperone activity [GO:0140849]; DNA binding [GO:0003677]; histone binding [GO:0042393]; histone chaperone activity [GO:0140713] 0.96944 -3.5427 MSLAGGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.60655 0 0 9.11327 Q15910 EZH2_HUMAN Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6) EZH2 KMT6 Homo sapiens (Human) "B cell differentiation [GO:0030183]; cardiac muscle hypertrophy in response to stress [GO:0014898]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to trichostatin A [GO:0035984]; cerebellar cortex development [GO:0021695]; chromatin organization [GO:0006325]; DNA methylation [GO:0006306]; facultative heterochromatin formation [GO:0140718]; G1 to G0 transition [GO:0070314]; G1/S transition of mitotic cell cycle [GO:0000082]; hepatocyte homeostasis [GO:0036333]; heterochromatin formation [GO:0031507]; hippocampus development [GO:0021766]; histone H3-K27 trimethylation [GO:0098532]; keratinocyte differentiation [GO:0030216]; liver regeneration [GO:0097421]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of retinoic acid receptor signaling pathway [GO:0048387]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of striated muscle cell differentiation [GO:0051154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of dendrite development [GO:1900006]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein localization to chromatin [GO:0071168]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-templated transcription [GO:0006355]; regulation of gliogenesis [GO:0014013]; regulation of kidney development [GO:0090183]; response to estradiol [GO:0032355]; response to tetrachloromethane [GO:1904772]; rhythmic process [GO:0048511]; skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration [GO:0014834]; stem cell differentiation [GO:0048863]; subtelomeric heterochromatin formation [GO:0031509]; synaptic transmission, GABAergic [GO:0051932]" "chromatin [GO:0000785]; chromatin silencing complex [GO:0005677]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; ESC/E(Z) complex [GO:0035098]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; pronucleus [GO:0045120]; synapse [GO:0045202]" chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; histone H3K27 methyltransferase activity [GO:0046976]; histone H3K27 trimethyltransferase activity [GO:0140951]; histone methyltransferase activity [GO:0042054]; lncRNA binding [GO:0106222]; primary miRNA binding [GO:0070878]; promoter-specific chromatin binding [GO:1990841]; protein-lysine N-methyltransferase activity [GO:0016279]; ribonucleoprotein complex binding [GO:0043021]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; transcription corepressor activity [GO:0003714]; transcription corepressor binding [GO:0001222] 0.95521 -1.5532 AQCNTKQCPCYLAVR 0 0 0 0 0 0 0 0 0 0 0 0 9.20139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15911 ZFHX3_HUMAN Zinc finger homeobox protein 3 (AT motif-binding factor 1) (AT-binding transcription factor 1) (Alpha-fetoprotein enhancer-binding protein) (Zinc finger homeodomain protein 3) (ZFH-3) ZFHX3 ATBF1 C16orf47 Homo sapiens (Human) brain development [GO:0007420]; circadian regulation of gene expression [GO:0032922]; muscle organ development [GO:0007517]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell adhesion [GO:0045785]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of DNA-templated transcription [GO:0006355]; regulation of locomotor rhythm [GO:1904059]; regulation of neuron differentiation [GO:0045664]; regulation of transcription by RNA polymerase II [GO:0006357]; response to transforming growth factor beta [GO:0071559] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; transcription cis-regulatory region binding [GO:0000976]; zinc ion binding [GO:0008270]" 0.88719 -0.34278 DVPNNVDLSKFDGFVLYGKR 0 12.1586 11.5273 0 0 0 0 11.3517 9.9357 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1219 0 0 0 Q15928 ZN141_HUMAN Zinc finger protein 141 ZNF141 D4S90 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; limb morphogenesis [GO:0035108]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355]; transcription by RNA polymerase II [GO:0006366] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.93311 -1.288 AFGRSRVLNEHK 0 0 0 0 0 0 8.7149 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q15937 ZNF79_HUMAN Zinc finger protein 79 (ZNFpT7) ZNF79 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.66091 0.39491 SPSPGWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.23384 Q15942 ZYX_HUMAN Zyxin (Zyxin-2) ZYX Homo sapiens (Human) cell-cell signaling [GO:0007267]; cell-matrix adhesion [GO:0007160]; cellular response to type II interferon [GO:0071346]; integrin-mediated signaling pathway [GO:0007229]; regulation of inflammatory response [GO:0050727]; stress fiber assembly [GO:0043149]; transforming growth factor beta receptor signaling pathway [GO:0007179] actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725] metal ion binding [GO:0046872]; RNA binding [GO:0003723] 0.87137 0.061841 VSSGYVPPPVATPFSSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.761 0 0 0 0 0 Q15973 ZN124_HUMAN Zinc finger protein 124 (Zinc finger protein HZF-16) ZNF124 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.96901 -4.2039 AFRYASSLQKHEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.4066 0 10.0926 0 0 0 0 0 0 0 0 0 Q16082 HSPB2_HUMAN Heat shock protein beta-2 (HspB2) (DMPK-binding protein) (MKBP) HSPB2 Homo sapiens (Human) response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; somatic muscle development [GO:0007525] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] enzyme activator activity [GO:0008047]; structural constituent of eye lens [GO:0005212] 0.95444 -1.5117 HGFVSREFCR 0 0 8.90174 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q16099 GRIK4_HUMAN "Glutamate receptor ionotropic, kainate 4 (GluK4) (Excitatory amino acid receptor 1) (EAA1) (Glutamate receptor KA-1) (KA1)" GRIK4 GRIK Homo sapiens (Human) "chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; synaptic transmission, glutamatergic [GO:0035249]" hippocampal mossy fiber to CA3 synapse [GO:0098686]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; presynaptic membrane [GO:0042734] kainate selective glutamate receptor activity [GO:0015277]; ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315] 0.96336 -2.2419 DSEYETAETMCQILPK 0 0 9.22771 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5779 0 0 0 0 0 0 0 9.80502 0 0 Q16181 SEPT7_HUMAN Septin-7 (CDC10 protein homolog) SEPTIN7 CDC10 SEPT7 Homo sapiens (Human) cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; cytoskeleton-dependent cytokinesis [GO:0061640]; positive regulation of non-motile cilium assembly [GO:1902857]; regulation of embryonic cell shape [GO:0016476]; spermatogenesis [GO:0007283] axoneme [GO:0005930]; cell division site [GO:0032153]; cleavage furrow [GO:0032154]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; kinetochore [GO:0000776]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; non-motile cilium [GO:0097730]; nucleus [GO:0005634]; septin complex [GO:0031105]; septin ring [GO:0005940]; sperm annulus [GO:0097227]; spindle [GO:0005819]; stress fiber [GO:0001725] cadherin binding [GO:0045296]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; molecular adaptor activity [GO:0060090]; structural molecule activity [GO:0005198] 0.88098 -0.30772 GQLTKSPLAQMEEER 0 0 0 0 0 0 0 0 0 0 8.91615 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q16186 ADRM1_HUMAN Proteasomal ubiquitin receptor ADRM1 (110 kDa cell membrane glycoprotein) (Gp110) (Adhesion-regulating molecule 1) (ARM-1) (Proteasome regulatory particle non-ATPase 13) (hRpn13) (Rpn13 homolog) ADRM1 GP110 Homo sapiens (Human) proteasome assembly [GO:0043248]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; transcription elongation by RNA polymerase II [GO:0006368] "cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; proteasome complex [GO:0000502]; proteasome regulatory particle, lid subcomplex [GO:0008541]" endopeptidase activator activity [GO:0061133]; molecular function inhibitor activity [GO:0140678]; protease binding [GO:0002020]; proteasome binding [GO:0070628] 0.010256 1.9845 AGKMSLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6977 0 9.03518 0 0 0 0 0 0 0 9.77096 0 Q16204 CCDC6_HUMAN Coiled-coil domain-containing protein 6 (Papillary thyroid carcinoma-encoded protein) (Protein H4) CCDC6 D10S170 TST1 Homo sapiens (Human) cytoskeleton [GO:0005856]; cytosol [GO:0005829] identical protein binding [GO:0042802]; SH3 domain binding [GO:0017124]; structural constituent of cytoskeleton [GO:0005200] 0.96936 -3.5498 ALQEENRDLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.34747 0 0 0 0 0 9.39341 0 0 0 10.0388 0 Q16206 ENOX2_HUMAN Ecto-NOX disulfide-thiol exchanger 2 (APK1 antigen) (Cytosolic ovarian carcinoma antigen 1) (Tumor-associated hydroquinone oxidase) (tNOX) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)] ENOX2 COVA1 Homo sapiens (Human) electron transport chain [GO:0022900]; ultradian rhythm [GO:0007624] cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723] 0.96431 -2.6837 LGSSTDK 0 0 0 0 0 0 0 0 0 0 0 0 8.93846 0 0 0 0 8.90382 0 0 0 0 0 0 0 0 8.71956 Q16222 UAP1_HUMAN UDP-N-acetylhexosamine pyrophosphorylase (Antigen X) (AGX) (Sperm-associated antigen 2) [Includes: UDP-N-acetylgalactosamine pyrophosphorylase (EC 2.7.7.83) (AGX-1); UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) (AGX-2)] UAP1 SPAG2 Homo sapiens (Human) UDP-N-acetylglucosamine biosynthetic process [GO:0006048] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] identical protein binding [GO:0042802]; UDP-N-acetylgalactosamine diphosphorylase activity [GO:0052630]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977] 0.92121 -1.1056 FVFDIFQFAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4825 0 Q16236 NF2L2_HUMAN "Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nrf-2) (HEBP1) (Nuclear factor, erythroid derived 2, like 2)" NFE2L2 NRF2 Homo sapiens (Human) aflatoxin catabolic process [GO:0046223]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to angiotensin [GO:1904385]; cellular response to copper ion [GO:0071280]; cellular response to fluid shear stress [GO:0071498]; cellular response to glucose starvation [GO:0042149]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to laminar fluid shear stress [GO:0071499]; cellular response to oxidative stress [GO:0034599]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to xenobiotic stimulus [GO:0071466]; endoplasmic reticulum unfolded protein response [GO:0030968]; inflammatory response [GO:0006954]; integrated stress response signaling [GO:0140467]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of hematopoietic stem cell differentiation [GO:1902037]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood coagulation [GO:0030194]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903071]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose import [GO:0046326]; positive regulation of glutathione biosynthetic process [GO:1903788]; positive regulation of neuron projection development [GO:0010976]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of embryonic development [GO:0045995]; regulation of innate immune response [GO:0045088]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription by RNA polymerase II [GO:0006357]; response to lithium ion [GO:0010226]; response to oxidative stress [GO:0006979] centrosome [GO:0005813]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription regulator complex [GO:0090575] "DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein domain specific binding [GO:0019904]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific DNA binding [GO:0043565]; transcription cis-regulatory region binding [GO:0000976]; transcription coregulator binding [GO:0001221]; ubiquitin protein ligase binding [GO:0031625]" 0.96376 -2.2258 ERQEQLQKEQEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0283 0 0 0 0 0 0 0 0 0 0 0 0 Q16280 CNGA2_HUMAN Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (Cyclic nucleotide-gated channel alpha-2) (CNG channel alpha-2) (CNG-2) (CNG2) CNGA2 CNCA CNCA1 CNCG2 Homo sapiens (Human) monoatomic cation transmembrane transport [GO:0098655]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608] ciliary membrane [GO:0060170]; Golgi-associated vesicle membrane [GO:0030660]; intracellular cyclic nucleotide activated cation channel complex [GO:0017071]; plasma membrane [GO:0005886] calmodulin binding [GO:0005516]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; intracellular cAMP-activated cation channel activity [GO:0005222]; intracellular cGMP-activated cation channel activity [GO:0005223]; protein-containing complex binding [GO:0044877] 0.9131 -0.78719 LRAEIAINVHLSTLK 0 0 0 0 0 0 8.90545 0 8.97888 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q16281 CNGA3_HUMAN Cyclic nucleotide-gated cation channel alpha-3 (Cone photoreceptor cGMP-gated channel subunit alpha) (Cyclic nucleotide-gated channel alpha-3) (CNG channel alpha-3) (CNG-3) (CNG3) CNGA3 CNCG3 Homo sapiens (Human) inorganic cation import across plasma membrane [GO:0098659]; monoatomic cation transmembrane transport [GO:0098655]; monoatomic cation transport [GO:0006812]; response to cAMP [GO:0051591]; response to corticosteroid [GO:0031960]; response to magnesium ion [GO:0032026]; signal transduction [GO:0007165]; visual perception [GO:0007601] axon initial segment [GO:0043194]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; glial cell projection [GO:0097386]; intracellular cyclic nucleotide activated cation channel complex [GO:0017071]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; transmembrane transporter complex [GO:1902495] cadherin binding [GO:0045296]; cGMP binding [GO:0030553]; intracellular cAMP-activated cation channel activity [GO:0005222]; intracellular cGMP-activated cation channel activity [GO:0005223]; ligand-gated monoatomic ion channel activity [GO:0015276]; myosin binding [GO:0017022]; protein-containing complex binding [GO:0044877] 0.9675 -2.7959 DLETRVIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.357 0 0 0 0 0 0 0 0 0 0 Q16342 PDCD2_HUMAN Programmed cell death protein 2 (Zinc finger MYND domain-containing protein 7) (Zinc finger protein Rp-8) PDCD2 RP8 ZMYND7 Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; regulation of hematopoietic progenitor cell differentiation [GO:1901532] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleus [GO:0005634] DNA binding [GO:0003677]; enzyme binding [GO:0019899]; metal ion binding [GO:0046872] 0.96758 -2.8187 CHKAYYCSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2812 0 0 0 0 0 0 10.8917 0 0 Q16348 S15A2_HUMAN "Solute carrier family 15 member 2 (Kidney H(+)/peptide cotransporter) (Oligopeptide transporter, kidney isoform) (Peptide transporter 2)" SLC15A2 PEPT2 Homo sapiens (Human) dipeptide import across plasma membrane [GO:0140206]; dipeptide transport [GO:0042938]; innate immune response [GO:0045087]; monoatomic ion transport [GO:0006811]; peptidoglycan transport [GO:0015835]; protein transport [GO:0015031]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424]; renal absorption [GO:0070293]; transport across blood-brain barrier [GO:0150104]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961]; xenobiotic transport [GO:0042908] apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886] dipeptide transmembrane transporter activity [GO:0071916]; peptide:proton symporter activity [GO:0015333] 0.7583 0.29954 HIPHIQGNMIK 12.879 12.8625 12.7112 10.2999 10.5862 10.4722 12.1899 12.4629 12.5767 8.32953 12.7454 12.6611 10.485 10.5796 10.5741 11.398 11.1083 10.8761 0 0 0 0 0 0 0 0 0 Q16352 AINX_HUMAN Alpha-internexin (Alpha-Inx) (66 kDa neurofilament protein) (NF-66) (Neurofilament-66) (Neurofilament 5) INA NEF5 Homo sapiens (Human) cell differentiation [GO:0030154]; cellular response to leukemia inhibitory factor [GO:1990830]; intermediate filament organization [GO:0045109]; neurofilament cytoskeleton organization [GO:0060052]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; substantia nigra development [GO:0021762] cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; extracellular space [GO:0005615]; intermediate filament [GO:0005882]; neurofilament [GO:0005883]; postsynaptic intermediate filament cytoskeleton [GO:0099160]; Schaffer collateral - CA1 synapse [GO:0098685] structural constituent of cytoskeleton [GO:0005200]; structural constituent of postsynaptic intermediate filament cytoskeleton [GO:0099184] 0.96998 -5.1456 CEEESRGR 0 0 13.0188 9.97885 9.13175 9.25505 0 0 10.3155 10.8039 0 0 10.4742 0 10.4503 0 0 0 0 0 0 10.938 0 0 0 0 0 Q16363 LAMA4_HUMAN Laminin subunit alpha-4 (Laminin-14 subunit alpha) (Laminin-8 subunit alpha) (Laminin-9 subunit alpha) LAMA4 Homo sapiens (Human) cell adhesion [GO:0007155]; negative regulation of cold-induced thermogenesis [GO:0120163]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995] basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576] extracellular matrix structural constituent [GO:0005201]; signaling receptor binding [GO:0005102] 0.96065 -1.9952 CERCAPGYYGDAR 0 0 0 0 0 0 11.2437 0 0 0 0 0 0 0 9.69444 0 11.1075 0 0 0 0 0 9.80106 0 0 0 0 Q16384 SSX1_HUMAN "Protein SSX1 (Cancer/testis antigen 5.1) (CT5.1) (Synovial sarcoma, X breakpoint 1)" SSX1 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] transcription corepressor activity [GO:0003714] 0.88466 -0.20411 INKRSGPK 9.72969 9.74861 9.76762 0 0 0 0 0 0 9.91792 10.0217 0 0 0 0 0 0 0 0 0 0 0 0 0 9.41794 0 0 Q16385 SSX2_HUMAN "Protein SSX2 (Cancer/testis antigen 5.2) (CT5.2) (Synovial sarcoma, X breakpoint 2) (Tumor antigen HOM-MEL-40)" SSX2 SSX2A; SSX2B Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] 0.91533 -0.79606 GEHAWTHRLRER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.93528 0 10.3326 0 0 Q16394 EXT1_HUMAN Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 1) (Putative tumor suppressor protein EXT1) EXT1 Homo sapiens (Human) "antigen processing and presentation [GO:0019882]; axon guidance [GO:0007411]; basement membrane organization [GO:0071711]; blood vessel remodeling [GO:0001974]; BMP signaling pathway [GO:0030509]; bone resorption [GO:0045453]; canonical Wnt signaling pathway [GO:0060070]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; cell adhesion mediated by integrin [GO:0033627]; cell fate commitment [GO:0045165]; cellular response to virus [GO:0098586]; chondrocyte hypertrophy [GO:0003415]; chondrocyte proliferation [GO:0035988]; chondroitin sulfate metabolic process [GO:0030204]; collagen fibril organization [GO:0030199]; cranial skeletal system development [GO:1904888]; dendrite self-avoidance [GO:0070593]; dendritic cell migration [GO:0036336]; developmental growth involved in morphogenesis [GO:0060560]; embryonic skeletal joint development [GO:0072498]; endochondral bone growth [GO:0003416]; endochondral ossification [GO:0001958]; endoderm development [GO:0007492]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; fear response [GO:0042596]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fluid transport [GO:0042044]; gastrulation [GO:0007369]; gene expression [GO:0010467]; glandular epithelial cell differentiation [GO:0002067]; glomerular basement membrane development [GO:0032836]; glycosaminoglycan biosynthetic process [GO:0006024]; hair follicle morphogenesis [GO:0031069]; heart contraction [GO:0060047]; heart field specification [GO:0003128]; hematopoietic stem cell differentiation [GO:0060218]; hematopoietic stem cell homeostasis [GO:0061484]; hematopoietic stem cell migration to bone marrow [GO:0097241]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; heparin biosynthetic process [GO:0030210]; hypersensitivity [GO:0002524]; leukocyte tethering or rolling [GO:0050901]; limb joint morphogenesis [GO:0036022]; lymphocyte adhesion to endothelial cell of high endothelial venule [GO:0036339]; lymphocyte migration into lymphoid organs [GO:0097021]; mesenchymal cell differentiation involved in bone development [GO:1901706]; mesoderm development [GO:0007498]; motor behavior [GO:0061744]; multicellular organism growth [GO:0035264]; multicellular organismal-level water homeostasis [GO:0050891]; neural crest cell differentiation [GO:0014033]; olfactory bulb development [GO:0021772]; optic nerve development [GO:0021554]; ossification [GO:0001503]; ossification involved in bone maturation [GO:0043931]; perichondral bone morphogenesis [GO:0061974]; podocyte differentiation [GO:0072112]; polysaccharide biosynthetic process [GO:0000271]; protein catabolic process [GO:0030163]; protein glycosylation [GO:0006486]; protein-containing complex assembly [GO:0065003]; regulation of blood pressure [GO:0008217]; response to heparin [GO:0071503]; response to leukemia inhibitory factor [GO:1990823]; response to light intensity [GO:0009642]; sebaceous gland development [GO:0048733]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; smoothened signaling pathway involved in lung development [GO:0060506]; social behavior [GO:0035176]; sodium ion homeostasis [GO:0055078]; stem cell division [GO:0017145]; stomach development [GO:0062094]; sulfation [GO:0051923]; sweat gland development [GO:0060792]; synaptic transmission, glutamatergic [GO:0035249]; tight junction organization [GO:0120193]; TNFSF11-mediated signaling pathway [GO:0071847]; vacuole organization [GO:0007033]; vasodilation [GO:0042311]; vocalization behavior [GO:0071625]; wound healing [GO:0042060]" endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; synapse [GO:0045202] acetylglucosaminyltransferase activity [GO:0008375]; glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity [GO:0050508]; glucuronosyltransferase activity [GO:0015020]; glycosyltransferase activity [GO:0016757]; heparan sulfate N-acetylglucosaminyltransferase activity [GO:0042328]; metal ion binding [GO:0046872]; N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity [GO:0050509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803] 0.81981 0.21926 YLTGIGSDTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5664 0 0 0 0 Q16478 GRIK5_HUMAN "Glutamate receptor ionotropic, kainate 5 (GluK5) (Excitatory amino acid receptor 2) (EAA2) (Glutamate receptor KA-2) (KA2)" GRIK5 GRIK2 Homo sapiens (Human) "cellular response to glucose stimulus [GO:0071333]; establishment of localization in cell [GO:0051649]; excitatory postsynaptic potential [GO:0060079]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of neuron apoptotic process [GO:0043525]; protein retention in ER lumen [GO:0006621]; receptor clustering [GO:0043113]; regulation of synaptic vesicle fusion to presynaptic active zone membrane [GO:0031630]; synaptic transmission, glutamatergic [GO:0035249]" dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; kainate selective glutamate receptor complex [GO:0032983]; nucleoplasm [GO:0005654]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; presynaptic membrane [GO:0042734]; terminal bouton [GO:0043195] identical protein binding [GO:0042802]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; SH3 domain binding [GO:0017124]; transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315] 0.93181 -1.2545 DSQYETTDTMCQILPK 0 0 0 0 9.81826 0 0 0 0 0 10.6384 10.5189 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q16512 PKN1_HUMAN Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein kinase C-like 1) (Protein kinase C-like PKN) (Protein kinase PKN-alpha) (Protein-kinase C-related kinase 1) (Serine-threonine protein kinase N) PKN1 PAK1 PKN PRK1 PRKCL1 Homo sapiens (Human) B cell apoptotic process [GO:0001783]; B cell homeostasis [GO:0001782]; epithelial cell migration [GO:0010631]; hyperosmotic response [GO:0006972]; intracellular signal transduction [GO:0035556]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of protein kinase activity [GO:0006469]; peptidyl-serine phosphorylation [GO:0018105]; post-translational protein modification [GO:0043687]; protein phosphorylation [GO:0006468]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of cell motility [GO:2000145]; regulation of germinal center formation [GO:0002634]; regulation of immunoglobulin production [GO:0002637]; regulation of transcription by RNA polymerase II [GO:0006357]; renal system process [GO:0003014]; signal transduction [GO:0007165]; spleen development [GO:0048536] cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] ATP binding [GO:0005524]; calcium-dependent protein kinase C activity [GO:0004698]; chromatin binding [GO:0003682]; histone binding [GO:0042393]; histone deacetylase binding [GO:0042826]; histone H3T11 kinase activity [GO:0035402]; nuclear androgen receptor binding [GO:0050681]; nuclear receptor coactivator activity [GO:0030374]; protein kinase activity [GO:0004672]; protein kinase C activity [GO:0004697]; protein kinase C binding [GO:0005080]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; small GTPase binding [GO:0031267] 0.87675 -0.007475 ELELAVFWR 9.00065 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2668 0 Q16513 PKN2_HUMAN Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2) PKN2 PRK2 PRKCL2 Homo sapiens (Human) apical junction assembly [GO:0043297]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell projection organization [GO:0030030]; epithelial cell migration [GO:0010631]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cytokinesis [GO:0032467]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of viral genome replication [GO:0045070]; protein phosphorylation [GO:0006468]; regulation of cell motility [GO:2000145]; signal transduction [GO:0007165] apical junction complex [GO:0043296]; centrosome [GO:0005813]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; intermediate filament cytoskeleton [GO:0045111]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calcium-dependent protein kinase C activity [GO:0004698]; histone deacetylase binding [GO:0042826]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; RNA binding [GO:0003723]; RNA polymerase binding [GO:0070063]; small GTPase binding [GO:0031267] 0.96916 -3.0387 EGAENLRKVTTDK 0 0 0 0 0 0 0 8.80019 0 0 0 10.0751 0 0 0 16.0045 0 0 9.85848 0 11.1676 0 0 12.3696 9.60615 0 0 Q16520 BATF_HUMAN Basic leucine zipper transcriptional factor ATF-like (B-cell-activating transcription factor) (B-ATF) (SF-HT-activated gene 2 protein) (SFA-2) BATF Homo sapiens (Human) "defense response to protozoan [GO:0042832]; DNA damage response [GO:0006974]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; hematopoietic stem cell differentiation [GO:0060218]; integrated stress response signaling [GO:0140467]; isotype switching [GO:0045190]; lymphoid progenitor cell differentiation [GO:0002320]; myeloid dendritic cell differentiation [GO:0043011]; positive regulation of cytokine production [GO:0001819]; regulation of T-helper 17 cell differentiation [GO:2000319]; regulation of transcription by RNA polymerase II [GO:0006357]; T-helper 17 cell differentiation [GO:0072539]; T-helper 17 cell lineage commitment [GO:0072540]; T-helper 2 cell differentiation [GO:0045064]" chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.8835 -0.26977 EIKQLTEELK 0 0 0 0 0 0 0 0 11.8612 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q16531 DDB1_HUMAN DNA damage-binding protein 1 (DDB p127 subunit) (DNA damage-binding protein a) (DDBa) (Damage-specific DNA-binding protein 1) (HBV X-associated protein 1) (XAP-1) (UV-damaged DNA-binding factor) (UV-damaged DNA-binding protein 1) (UV-DDB 1) (XPE-binding factor) (XPE-BF) (Xeroderma pigmentosum group E-complementing protein) (XPCe) DDB1 XAP1 Homo sapiens (Human) apoptotic process [GO:0006915]; biological process involved in interaction with symbiont [GO:0051702]; cellular response to UV [GO:0034644]; DNA damage response [GO:0006974]; DNA repair [GO:0006281]; ectopic germ cell programmed cell death [GO:0035234]; negative regulation of apoptotic process [GO:0043066]; negative regulation of developmental process [GO:0051093]; negative regulation of reproductive process [GO:2000242]; nucleotide-excision repair [GO:0006289]; positive regulation by virus of viral protein levels in host cell [GO:0046726]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of viral genome replication [GO:0045070]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of circadian rhythm [GO:0042752]; regulation of mitotic cell cycle phase transition [GO:1901990]; rhythmic process [GO:0048511]; ubiquitin-dependent protein catabolic process [GO:0006511]; UV-damage excision repair [GO:0070914]; viral release from host cell [GO:0019076]; Wnt signaling pathway [GO:0016055] "chromosome, telomeric region [GO:0000781]; Cul4-RING E3 ubiquitin ligase complex [GO:0080008]; Cul4A-RING E3 ubiquitin ligase complex [GO:0031464]; Cul4B-RING E3 ubiquitin ligase complex [GO:0031465]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]" cullin family protein binding [GO:0097602]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; protein-containing complex binding [GO:0044877]; protein-macromolecule adaptor activity [GO:0030674]; WD40-repeat domain binding [GO:0071987] 0.91296 -0.82228 EATADDLIK 8.05767 0 0 9.90127 9.12866 9.30367 10.6715 9.25368 10.0627 9.83873 14.95 0 0 9.09376 0 0 0 9.07178 9.46675 9.75682 0 0 10.6684 0 0 9.60268 0 Q16533 SNPC1_HUMAN snRNA-activating protein complex subunit 1 (SNAPc subunit 1) (Proximal sequence element-binding transcription factor subunit gamma) (PSE-binding factor subunit gamma) (PTF subunit gamma) (Small nuclear RNA-activating complex polypeptide 1) (snRNA-activating protein complex 43 kDa subunit) (SNAPc 43 kDa subunit) SNAPC1 SNAP43 Homo sapiens (Human) snRNA transcription by RNA polymerase II [GO:0042795]; snRNA transcription by RNA polymerase III [GO:0042796] nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; snRNA-activating protein complex [GO:0019185] RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; sequence-specific DNA binding [GO:0043565] 0.96392 -2.4078 AEVTEEFKDPSDRVMK 0 0 9.86797 0 0 0 0 0 0 0 0 0 0 0 0 0 13.1242 0 0 0 0 0 0 0 0 0 0 Q16534 HLF_HUMAN Hepatic leukemia factor HLF Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; rhythmic process [GO:0048511]; skeletal muscle cell differentiation [GO:0035914] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575] "DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; double-stranded DNA binding [GO:0003690]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.84792 0.1705 SLLENPLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.2363 0 0 0 0 0 0 0 0 0 0 0 Q16538 GP162_HUMAN Probable G-protein coupled receptor 162 (Gene-rich cluster gene A protein) GPR162 GRCA Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930] 0.090737 1.2056 LSLGSPESR 0 0 11.4977 0 0 0 0 0 0 0 0 0 0 0 0 0 12.1782 11.5102 0 0 0 0 0 0 9.14499 8.52888 0 Q16543 CDC37_HUMAN "Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) [Cleaved into: Hsp90 co-chaperone Cdc37, N-terminally processed]" CDC37 CDC37A Homo sapiens (Human) positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; post-transcriptional regulation of gene expression [GO:0010608]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; protein targeting [GO:0006605]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; regulation of type II interferon-mediated signaling pathway [GO:0060334] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; HSP90-CDC37 chaperone complex [GO:1990565]; protein folding chaperone complex [GO:0101031] heat shock protein binding [GO:0031072]; Hsp90 protein binding [GO:0051879]; kinase binding [GO:0019900]; protein kinase binding [GO:0019901]; protein kinase regulator activity [GO:0019887]; protein-folding chaperone binding [GO:0051087]; scaffold protein binding [GO:0097110]; unfolded protein binding [GO:0051082] 0 6.5259 ACFRQFFTK 0 0 0 0 0 0 0 0 0 11.493 9.33559 9.17993 0 0 0 0 9.07802 0 0 0 0 0 9.27079 9.24987 0 0 0 Q16548 B2LA1_HUMAN Bcl-2-related protein A1 (Bcl-2-like protein 5) (Bcl2-L-5) (Hemopoietic-specific early response protein) (Protein BFL-1) (Protein GRS) BCL2A1 BCL2L5 BFL1 GRS HBPA1 Homo sapiens (Human) extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitochondrial fusion [GO:0008053]; negative regulation of apoptotic process [GO:0043066]; positive regulation of apoptotic process [GO:0043065]; release of cytochrome c from mitochondria [GO:0001836] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741] channel activity [GO:0015267]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803] 0.5749 0.47864 QQIAPDVDTYK 0 9.29476 0 0 0 0 0 0 0 0 0 0 0 9.52834 0 0 0 0 0 0 0 0 0 0 0 0 0 Q16555 DPYL2_HUMAN Dihydropyrimidinase-related protein 2 (DRP-2) (Collapsin response mediator protein 2) (CRMP-2) (N2A3) (Unc-33-like phosphoprotein 2) (ULIP-2) DPYSL2 CRMP2 ULIP2 Homo sapiens (Human) cell differentiation [GO:0030154]; cytoskeleton organization [GO:0007010]; endocytosis [GO:0006897]; nervous system development [GO:0007399]; nucleobase-containing compound metabolic process [GO:0006139]; signal transduction [GO:0007165] cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] "dihydropyrimidinase activity [GO:0004157]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [GO:0016812]; identical protein binding [GO:0042802]" 0.88391 -0.17395 KNIPRITSDR 0 0 0 0 0 0 0 0 0 10.5218 0 0 9.06706 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q16566 KCC4_HUMAN Calcium/calmodulin-dependent protein kinase type IV (CaMK IV) (EC 2.7.11.17) (CaM kinase-GR) CAMK4 CAMK CAMK-GR CAMKIV Homo sapiens (Human) adaptive immune response [GO:0002250]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; long-term memory [GO:0007616]; myeloid dendritic cell differentiation [GO:0043011]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of DNA-templated transcription [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of osteoclast differentiation [GO:0045670]; regulation of T cell differentiation in thymus [GO:0033081]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; glutamatergic synapse [GO:0098978]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794] ATP binding [GO:0005524]; calcium-dependent protein serine/threonine kinase activity [GO:0009931]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; protein serine kinase activity [GO:0106310] 0.93298 -1.2851 DAADAVK 0 0 0 0 9.02644 0 0 8.91719 0 8.68387 10.1609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q16576 RBBP7_HUMAN Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) RBBP7 RBAP46 Homo sapiens (Human) brain development [GO:0007420]; cellular heat acclimation [GO:0070370]; chromatin remodeling [GO:0006338]; DNA replication [GO:0006260]; histone deacetylation [GO:0016575]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of stem cell population maintenance [GO:1902459]; regulation of cell fate specification [GO:0042659]; regulation of DNA-templated transcription [GO:0006355]; regulation of stem cell differentiation [GO:2000736]; response to steroid hormone [GO:0048545] "ATPase complex [GO:1904949]; chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; ESC/E(Z) complex [GO:0035098]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NuRD complex [GO:0016581]; NURF complex [GO:0016589]; Sin3 complex [GO:0016580]" histone binding [GO:0042393]; RNA binding [GO:0003723] 0.92414 -1.0057 TVALWDLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.65703 0 0 0 0 0 0 0 0 0 Q16584 M3K11_HUMAN Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) MAP3K11 MLK3 PTK1 SPRK Homo sapiens (Human) cell cycle G1/S phase transition [GO:0044843]; cell death [GO:0008219]; JNK cascade [GO:0007254]; MAPK cascade [GO:0000165]; microtubule-based process [GO:0007017]; positive regulation of apoptotic process [GO:0043065]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron apoptotic process [GO:0043525]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468] centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; microtubule [GO:0005874] ATP binding [GO:0005524]; identical protein binding [GO:0042802]; JUN kinase kinase kinase activity [GO:0004706]; MAP kinase kinase kinase activity [GO:0004709]; mitogen-activated protein kinase kinase binding [GO:0031434]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; small GTPase binding [GO:0031267] 0.87233 0.037111 EIQGLFDELR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.67848 0 0 0 0 0 0 0 Q16585 SGCB_HUMAN Beta-sarcoglycan (Beta-SG) (43 kDa dystrophin-associated glycoprotein) (43DAG) (A3b) SGCB Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; gene expression [GO:0010467]; glucose homeostasis [GO:0042593]; glucose import in response to insulin stimulus [GO:0044381]; muscle organ development [GO:0007517]; response to glucose [GO:0009749]; vascular associated smooth muscle cell development [GO:0097084] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dystrophin-associated glycoprotein complex [GO:0016010]; plasma membrane [GO:0005886]; sarcoglycan complex [GO:0016012]; sarcolemma [GO:0042383] 0.95324 -1.501 SVNKEHNSNFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.24401 0 0 0 Q16587 ZNF74_HUMAN Zinc finger protein 74 (Zinc finger protein 520) (hZNF7) ZNF74 ZNF520 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] actin cytoskeleton [GO:0015629]; nucleoplasm [GO:0005654] metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.34304 0.77096 IHSGEKSFKCEK 0 0 0 0 0 0 0 9.63815 10.2057 0 0 0 0 0 0 0 0 0 0 0 9.45812 0 0 9.41428 10.7292 0 0 Q16594 TAF9_HUMAN Transcription initiation factor TFIID subunit 9 (RNA polymerase II TBP-associated factor subunit G) (STAF31/32) (Transcription initiation factor TFIID 31 kDa subunit) (TAFII-31) (TAFII31) (Transcription initiation factor TFIID 32 kDa subunit) (TAFII-32) (TAFII32) TAF9 TAF2G TAFII31 Homo sapiens (Human) box C/D snoRNP assembly [GO:0000492]; chromatin remodeling [GO:0006338]; DNA damage response [GO:0006974]; histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of response to cytokine stimulus [GO:0060760]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of DNA repair [GO:0006282]; regulation of DNA-templated transcription [GO:0006355]; regulation of RNA splicing [GO:0043484]; regulation of transcription by RNA polymerase II [GO:0006357]; response to interleukin-1 [GO:0070555]; response to L-glutamate [GO:1902065]; RNA polymerase II preinitiation complex assembly [GO:0051123] MLL1 complex [GO:0071339]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pre-snoRNP complex [GO:0070761]; SAGA complex [GO:0000124]; transcription factor TFIID complex [GO:0005669]; transcription factor TFTC complex [GO:0033276] ATPase binding [GO:0051117]; C2H2 zinc finger domain binding [GO:0070742]; DNA binding [GO:0003677]; DNA-binding transcription factor binding [GO:0140297]; p53 binding [GO:0002039]; protein heterodimerization activity [GO:0046982]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; transcription cis-regulatory region binding [GO:0000976]; transcription coactivator activity [GO:0003713] 0.89009 -0.48492 ATVDADDVR 9.83744 0 0 0 0 0 0 0 0 0 0 0 0 0 9.73162 0 0 0 0 0 0 0 0 0 0 0 0 Q16595 FRDA_HUMAN "Frataxin, mitochondrial (EC 1.16.3.1) (Friedreich ataxia protein) (Fxn) [Cleaved into: Frataxin intermediate form (i-FXN); Frataxin(56-210) (m56-FXN); Frataxin(78-210) (d-FXN) (m78-FXN); Frataxin mature form (Frataxin(81-210)) (m81-FXN); Extramitochondrial frataxin]" FXN FRDA X25 Homo sapiens (Human) [2Fe-2S] cluster assembly [GO:0044571]; [4Fe-4S] cluster assembly [GO:0044572]; adult walking behavior [GO:0007628]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; intracellular iron ion homeostasis [GO:0006879]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron ion transmembrane transport [GO:0034755]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; muscle cell cellular homeostasis [GO:0046716]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; organ growth [GO:0035265]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039] cytosol [GO:0005829]; iron-sulfur cluster assembly complex [GO:1990229]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial iron-sulfur cluster assembly complex [GO:0099128]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] "2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]" 0.95184 -1.3903 QIWLSSPSSGPKRYDWTGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7819 0 10.8417 0 0 0 0 Q16612 NREP_HUMAN Neuronal regeneration-related protein (Neuronal protein 3.1) (Protein p311) NREP C5orf13 P311 Homo sapiens (Human) axon regeneration [GO:0031103]; regulation of neuron differentiation [GO:0045664]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015] cytoplasm [GO:0005737]; nucleus [GO:0005634] 0.95151 -1.4236 ISYLHFF 0 0 0 0 0 0 0 0 0 12.3311 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q16613 SNAT_HUMAN Serotonin N-acetyltransferase (Serotonin acetylase) (EC 2.3.1.87) (Aralkylamine N-acetyltransferase) (AA-NAT) AANAT SNAT Homo sapiens (Human) cellular response to cAMP [GO:0071320]; circadian rhythm [GO:0007623]; indolalkylamine biosynthetic process [GO:0046219]; melatonin biosynthetic process [GO:0030187]; N-terminal protein amino acid acetylation [GO:0006474]; photoperiodism [GO:0009648]; response to calcium ion [GO:0051592]; response to copper ion [GO:0046688]; response to corticosterone [GO:0051412]; response to cytokine [GO:0034097]; response to insulin [GO:0032868]; response to light stimulus [GO:0009416]; response to prostaglandin E [GO:0034695]; response to zinc ion [GO:0010043] cytoplasm [GO:0005737]; cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471] 14-3-3 protein binding [GO:0071889]; aralkylamine N-acetyltransferase activity [GO:0004059]; arylamine N-acetyltransferase activity [GO:0004060] 0.90749 -0.74092 ERLMQESLTLHR 0 0 0 0 0 0 0 0 0 0 11.0935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q16619 CTF1_HUMAN Cardiotrophin-1 (CT-1) CTF1 Homo sapiens (Human) cell-cell signaling [GO:0007267]; leukemia inhibitory factor signaling pathway [GO:0048861]; muscle organ development [GO:0007517]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531] extracellular region [GO:0005576]; extracellular space [GO:0005615] cytokine activity [GO:0005125]; leukemia inhibitory factor receptor binding [GO:0005146] 0.89827 -0.56905 ALGAAVEALLAALGAANR 0 0 0 0 0 0 0 10.9865 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q16620 NTRK2_HUMAN BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Tropomyosin-related kinase B) NTRK2 TRKB Homo sapiens (Human) "brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; cellular response to amino acid stimulus [GO:0071230]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; central nervous system neuron development [GO:0021954]; cerebral cortex development [GO:0021987]; circadian rhythm [GO:0007623]; feeding behavior [GO:0007631]; glutamate secretion [GO:0014047]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; mechanoreceptor differentiation [GO:0042490]; myelination in peripheral nervous system [GO:0022011]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of anoikis [GO:2000811]; negative regulation of neuron apoptotic process [GO:0043524]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; neuronal action potential propagation [GO:0019227]; oligodendrocyte differentiation [GO:0048709]; peptidyl-serine phosphorylation [GO:0018105]; peripheral nervous system neuron development [GO:0048935]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of GTPase activity [GO:0043087]; regulation of protein kinase B signaling [GO:0051896]; retinal rod cell development [GO:0046548]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]; trans-synaptic signaling by neuropeptide, modulating synaptic transmission [GO:0099551]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]" axon [GO:0030424]; axon terminus [GO:0043679]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; receptor complex [GO:0043235]; terminal bouton [GO:0043195] ATP binding [GO:0005524]; brain-derived neurotrophic factor binding [GO:0048403]; brain-derived neurotrophic factor receptor activity [GO:0060175]; neurotrophin binding [GO:0043121]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803] 0.8839 -0.051695 GIHTLLQNLAK 0 0 0 0 0 0 0 9.02749 0 0 0 0 0 9.67442 0 0 0 0 0 0 0 0 0 9.28316 0 0 0 Q16621 NFE2_HUMAN "Transcription factor NF-E2 45 kDa subunit (Leucine zipper protein NF-E2) (Nuclear factor, erythroid-derived 2 45 kDa subunit) (p45 NF-E2)" NFE2 Homo sapiens (Human) hemostasis [GO:0007599]; integrated stress response signaling [GO:0140467]; nucleosome disassembly [GO:0006337]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription regulator complex [GO:0090575] "DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; WW domain binding [GO:0050699]" 0.9241 -1.053 GEAGSRDER 0 0 0 8.35821 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.002 0 Q16629 SRSF7_HUMAN "Serine/arginine-rich splicing factor 7 (Splicing factor 9G8) (Splicing factor, arginine/serine-rich 7)" SRSF7 SFRS7 Homo sapiens (Human) "cellular response to leukemia inhibitory factor [GO:1990830]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; RNA splicing [GO:0008380]" cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270] 0.9691 -3.9966 AFSYYGPLR 0 0 0 10.3592 0 9.49705 0 0 0 0 0 0 0 0 0 12.2384 0 0 0 0 0 0 0 0 9.1728 10.6234 8.75519 Q16630 CPSF6_HUMAN Cleavage and polyadenylation specificity factor subunit 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Cleavage factor Im complex 68 kDa subunit) (CFIm68) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII-4/7) CPSF6 CFIM68 Homo sapiens (Human) localization [GO:0051179]; messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA 3'-end processing [GO:0031124]; mRNA alternative polyadenylation [GO:0110104]; mRNA processing [GO:0006397]; positive regulation of RNA export from nucleus [GO:0046833]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262] cytoplasm [GO:0005737]; interchromatin granule [GO:0035061]; membrane [GO:0016020]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904] exon-exon junction complex binding [GO:1990448]; mRNA binding [GO:0003729]; ribosomal large subunit binding [GO:0043023]; RNA binding [GO:0003723] 0.59125 0.45755 GAAPNVVYTYTGK 0 0 0 0 0 0 0 0 0 0 0 9.12926 0 0 0 0 0 0 0 0 0 8.70207 0 0 0 0 0 Q16635 TAZ_HUMAN Tafazzin (Taz) (EC 2.3.1.-) (Protein G4.5) TAFAZZIN EFE2 G4.5 TAZ Homo sapiens (Human) cardiac muscle contraction [GO:0060048]; cardiac muscle tissue development [GO:0048738]; cardiolipin acyl-chain remodeling [GO:0035965]; cardiolipin biosynthetic process [GO:0032049]; cardiolipin metabolic process [GO:0032048]; cristae formation [GO:0042407]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; hemopoiesis [GO:0030097]; inner mitochondrial membrane organization [GO:0007007]; mitochondrial ATP synthesis coupled electron transport [GO:0042775]; mitochondrial respiratory chain complex I assembly [GO:0032981]; mitochondrion organization [GO:0007005]; mitophagy [GO:0000423]; muscle contraction [GO:0006936]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of cardiolipin metabolic process [GO:1900210]; skeletal muscle tissue development [GO:0007519]; spermatocyte division [GO:0048137] mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739] 1-acylglycerol-3-phosphate O-acyltransferase activity [GO:0003841]; 1-acylglycerophosphocholine O-acyltransferase activity [GO:0047184]; O-acyltransferase activity [GO:0008374] 0.86972 0.047485 ALTDFIQEEFQHLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.144 0 Q16643 DREB_HUMAN Drebrin (Developmentally-regulated brain protein) DBN1 D0S117E Homo sapiens (Human) actin filament organization [GO:0007015]; cell communication by chemical coupling [GO:0010643]; cell communication by electrical coupling [GO:0010644]; cytoplasmic sequestering of protein [GO:0051220]; generation of neurons [GO:0048699]; in utero embryonic development [GO:0001701]; maintenance of protein location in cell [GO:0032507]; neural precursor cell proliferation [GO:0061351]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of receptor localization to synapse [GO:1902685]; positive regulation of synaptic plasticity [GO:0031915]; regulation of dendrite development [GO:0050773]; regulation of neuronal synaptic plasticity [GO:0048168] actin cytoskeleton [GO:0015629]; actomyosin [GO:0042641]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dendrite [GO:0030425]; gap junction [GO:0005921]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211] actin binding [GO:0003779]; cadherin binding [GO:0045296]; profilin binding [GO:0005522] 0.94621 -1.3444 EQFWEQAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.32854 0 0 0 0 0 0 0 0 0 0 Q16647 PTGIS_HUMAN Prostacyclin synthase (EC 5.3.99.4) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152) (Prostaglandin I2 synthase) PTGIS CYP8 CYP8A1 Homo sapiens (Human) apoptotic signaling pathway [GO:0097190]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cyclooxygenase pathway [GO:0019371]; icosanoid metabolic process [GO:0006690]; NAD biosynthesis via nicotinamide riboside salvage pathway [GO:0034356]; negative regulation of inflammatory response [GO:0050728]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; positive regulation of angiogenesis [GO:0045766]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360]; prostaglandin biosynthetic process [GO:0001516] caveola [GO:0005901]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; nucleus [GO:0005634] "heme binding [GO:0020037]; hydroperoxy icosatetraenoate dehydratase activity [GO:0106256]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; prostaglandin-I synthase activity [GO:0008116]" 0.88121 -0.30275 DAASFLTRMK 0 0 0 0 0 0 0 8.58177 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q16649 NFIL3_HUMAN Nuclear factor interleukin-3-regulated protein (E4 promoter-binding protein 4) (Interleukin-3 promoter transcriptional activator) (Interleukin-3-binding protein 1) (Transcriptional activator NF-IL3A) NFIL3 E4BP4 IL3BP1 Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; circadian rhythm [GO:0007623]; immune response [GO:0006955]; natural killer cell differentiation [GO:0001779]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] chromatin [GO:0000785]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.95812 -1.6843 LSSPIDMTSK 0 0 0 0 0 0 0 0 0 0 0 9.69658 0 0 0 0 0 9.45629 0 0 0 0 0 0 0 0 0 Q16654 PDK4_HUMAN "[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 4)" PDK4 PDHK4 Homo sapiens (Human) cellular response to fatty acid [GO:0071398]; cellular response to starvation [GO:0009267]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; insulin receptor signaling pathway [GO:0008286]; negative regulation of anoikis [GO:2000811]; protein phosphorylation [GO:0006468]; reactive oxygen species metabolic process [GO:0072593]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]; regulation of bone resorption [GO:0045124]; regulation of cellular ketone metabolic process [GO:0010565]; regulation of fatty acid biosynthetic process [GO:0042304]; regulation of fatty acid oxidation [GO:0046320]; regulation of glucose metabolic process [GO:0010906]; regulation of pH [GO:0006885]; response to starvation [GO:0042594] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; pyruvate dehydrogenase (acetyl-transferring) kinase activity [GO:0004740] 0.91455 -0.7777 ALSSESIEKLPVFNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.69898 0 11.8991 0 0 0 0 0 0 0 0 0 0 Q16658 FSCN1_HUMAN Fascin (55 kDa actin-bundling protein) (Singed-like protein) (p55) FSCN1 FAN1 HSN SNL Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; cell migration [GO:0016477]; cell motility [GO:0048870]; cell-cell junction assembly [GO:0007043]; establishment of apical/basal cell polarity [GO:0035089]; establishment or maintenance of cell polarity [GO:0007163]; microspike assembly [GO:0030035]; parallel actin filament bundle assembly [GO:0030046]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of podosome assembly [GO:0071803]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of microvillus assembly [GO:0032534] actin cytoskeleton [GO:0015629]; cell cortex [GO:0005938]; cell projection membrane [GO:0031253]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; microspike [GO:0044393]; microvillus [GO:0005902]; podosome [GO:0002102]; ruffle [GO:0001726]; stress fiber [GO:0001725] actin binding [GO:0003779]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; protein-macromolecule adaptor activity [GO:0030674]; RNA binding [GO:0003723] 0.89902 -0.63704 DTKKCAFR 0 0 0 0 0 0 0 0 0 0 10.1118 9.03408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q16659 MK06_HUMAN Mitogen-activated protein kinase 6 (MAP kinase 6) (MAPK 6) (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97-MAPK) MAPK6 ERK3 PRKM6 Homo sapiens (Human) cell cycle [GO:0007049]; intracellular signal transduction [GO:0035556]; positive regulation of dendritic spine development [GO:0060999]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; septin cytoskeleton [GO:0032156] ATP binding [GO:0005524]; MAP kinase activity [GO:0004707]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.89853 -0.62523 GHLSEGLVTKWYR 0 0 0 0 0 9.1221 0 0 0 9.40967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q16665 HIF1A_HUMAN Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein) (Basic-helix-loop-helix-PAS protein MOP1) (Class E basic helix-loop-helix protein 78) (bHLHe78) (Member of PAS protein 1) (PAS domain-containing protein 8) HIF1A BHLHE78 MOP1 PASD8 Homo sapiens (Human) angiogenesis [GO:0001525]; axonal transport of mitochondrion [GO:0019896]; B-1 B cell homeostasis [GO:0001922]; bone mineralization [GO:0030282]; cardiac ventricle morphogenesis [GO:0003208]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to virus [GO:0098586]; cerebral cortex development [GO:0021987]; chondrocyte differentiation [GO:0002062]; collagen metabolic process [GO:0032963]; connective tissue replacement involved in inflammatory response wound healing [GO:0002248]; digestive tract morphogenesis [GO:0048546]; dopaminergic neuron differentiation [GO:0071542]; elastin metabolic process [GO:0051541]; embryonic hemopoiesis [GO:0035162]; embryonic placenta development [GO:0001892]; epithelial cell differentiation involved in mammary gland alveolus development [GO:0061030]; epithelial to mesenchymal transition [GO:0001837]; glandular epithelial cell maturation [GO:0002071]; heart looping [GO:0001947]; hemoglobin biosynthetic process [GO:0042541]; hypoxia-inducible factor-1alpha signaling pathway [GO:0097411]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; intestinal epithelial cell maturation [GO:0060574]; intracellular glucose homeostasis [GO:0001678]; intracellular iron ion homeostasis [GO:0006879]; intracellular oxygen homeostasis [GO:0032364]; iris morphogenesis [GO:0061072]; lactate metabolic process [GO:0006089]; lactation [GO:0007595]; mesenchymal cell apoptotic process [GO:0097152]; muscle cell cellular homeostasis [GO:0046716]; negative regulation of bone mineralization [GO:0030502]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of mesenchymal cell apoptotic process [GO:2001054]; negative regulation of miRNA transcription [GO:1902894]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of TOR signaling [GO:0032007]; neural crest cell migration [GO:0001755]; neural fold elevation formation [GO:0021502]; neuroblast proliferation [GO:0007405]; neuron apoptotic process [GO:0051402]; outflow tract morphogenesis [GO:0003151]; positive regulation of angiogenesis [GO:0045766]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine-mediated signaling pathway [GO:0070101]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of hormone biosynthetic process [GO:0046886]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of macroautophagy [GO:0016239]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of aerobic respiration [GO:1903715]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of glycolytic process [GO:0006110]; regulation of protein neddylation [GO:2000434]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; regulation of transforming growth factor beta2 production [GO:0032909]; response to hypoxia [GO:0001666]; response to iron ion [GO:0010039]; response to muscle activity [GO:0014850]; response to reactive oxygen species [GO:0000302]; retina vasculature development in camera-type eye [GO:0061298]; signal transduction [GO:0007165]; TOR signaling [GO:0031929]; vascular endothelial growth factor production [GO:0010573]; visual learning [GO:0008542] axon cytoplasm [GO:1904115]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; motile cilium [GO:0031514]; nuclear body [GO:0016604]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; RNA polymerase II transcription regulator complex [GO:0090575] "cis-regulatory region sequence-specific DNA binding [GO:0000987]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity [GO:0001217]; E-box binding [GO:0070888]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; Hsp90 protein binding [GO:0051879]; nuclear receptor binding [GO:0016922]; p53 binding [GO:0002039]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription coactivator binding [GO:0001223]; transcription regulator activator activity [GO:0140537]; ubiquitin protein ligase binding [GO:0031625]" 0.93313 -1.2654 TVTKDRMEDIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7702 0 Q16666 IF16_HUMAN Gamma-interferon-inducible protein 16 (Ifi-16) (Interferon-inducible myeloid differentiation transcriptional activator) IFI16 IFNGIP1 Homo sapiens (Human) activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; epigenetic regulation of gene expression [GO:0040029]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of AIM2 inflammasome complex assembly [GO:0140972]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of autophagy [GO:0010506] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; transcription factor binding [GO:0008134] 0.89745 -0.55142 AGPKGSK 0 11.0419 12.709 0 0 0 12.8837 0 0 0 0 0 0 0 11.1047 0 0 0 0 0 0 0 0 0 0 0 0 Q16670 ZSC26_HUMAN Zinc finger and SCAN domain-containing protein 26 (Protein SRE-ZBP) (Zinc finger protein 187) ZSCAN26 ZNF187 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.95151 -1.3982 GVQEQQVR 0 9.40535 0 0 0 10.1652 0 0 0 0 0 0 9.47454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q16671 AMHR2_HUMAN Anti-Muellerian hormone type-2 receptor (EC 2.7.11.30) (Anti-Muellerian hormone type II receptor) (AMH type II receptor) (MIS type II receptor) (MISRII) (MRII) AMHR2 AMHR MISR2 Homo sapiens (Human) anti-Mullerian hormone signaling pathway [GO:1990262]; blood vessel development [GO:0001568]; BMP signaling pathway [GO:0030509]; cellular response to growth factor stimulus [GO:0071363]; female gonad development [GO:0008585]; male gonad development [GO:0008584]; Mullerian duct regression [GO:0001880]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; protein phosphorylation [GO:0006468]; sex differentiation [GO:0007548]; transforming growth factor beta receptor signaling pathway [GO:0007179] plasma membrane [GO:0005886]; receptor complex [GO:0043235] "anti-Mullerian hormone receptor activity [GO:1990272]; ATP binding [GO:0005524]; hormone binding [GO:0042562]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; transforming growth factor beta receptor activity [GO:0005024]; transforming growth factor beta receptor activity, type II [GO:0005026]" 0.87429 0.024143 NPQPACTLSPV 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.88255 0 0 0 0 0 0 Q16674 MIA_HUMAN Melanoma-derived growth regulatory protein (Melanoma inhibitory activity protein) MIA Homo sapiens (Human) extracellular matrix organization [GO:0030198] extracellular space [GO:0005615] growth factor activity [GO:0008083] 0.84836 0.12411 LFWGGSVQGDYYGDLAAR 0 0 0 0 0 0 0 0 0 9.8534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q16678 CP1B1_HUMAN Cytochrome P450 1B1 (EC 1.14.14.1) (CYPIB1) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152) CYP1B1 Homo sapiens (Human) adrenal gland development [GO:0030325]; angiogenesis [GO:0001525]; arachidonic acid metabolic process [GO:0019369]; benzene-containing compound metabolic process [GO:0042537]; blood vessel endothelial cell migration [GO:0043534]; blood vessel morphogenesis [GO:0048514]; cell adhesion [GO:0007155]; cellular response to cAMP [GO:0071320]; cellular response to cortisol stimulus [GO:0071387]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to luteinizing hormone stimulus [GO:0071373]; cellular response to organic cyclic compound [GO:0071407]; cellular response to progesterone stimulus [GO:0071393]; cellular response to tumor necrosis factor [GO:0071356]; collagen fibril organization [GO:0030199]; DNA modification [GO:0006304]; endothelial cell migration [GO:0043542]; endothelial cell-cell adhesion [GO:0071603]; epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; estrous cycle [GO:0044849]; ganglion development [GO:0061548]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; male gonad development [GO:0008584]; membrane lipid catabolic process [GO:0046466]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; nitric oxide biosynthetic process [GO:0006809]; omega-hydroxylase P450 pathway [GO:0097267]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of translation [GO:0045727]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of reactive oxygen species metabolic process [GO:2000377]; response to arsenic-containing substance [GO:0046685]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to follicle-stimulating hormone [GO:0032354]; response to indole-3-methanol [GO:0071680]; response to nutrient [GO:0007584]; response to toxic substance [GO:0009636]; retinal blood vessel morphogenesis [GO:0061304]; retinal metabolic process [GO:0042574]; retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202]; sterol metabolic process [GO:0016125]; toxin metabolic process [GO:0009404]; trabecular meshwork development [GO:0002930]; xenobiotic metabolic process [GO:0006805] endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; nucleus [GO:0005634] "aromatase activity [GO:0070330]; estrogen 16-alpha-hydroxylase activity [GO:0101020]; heme binding [GO:0020037]; hydroperoxy icosatetraenoate dehydratase activity [GO:0106256]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]" 0.54629 0.57132 RCIGEELSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.81479 0 0 0 0 Q16698 DECR_HUMAN "2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial (EC 1.3.1.124) (2,4-dienoyl-CoA reductase [NADPH]) (4-enoyl-CoA reductase [NADPH]) (Short chain dehydrogenase/reductase family 18C member 1)" DECR1 DECR SDR18C1 Homo sapiens (Human) fatty acid beta-oxidation [GO:0006635]; positive regulation of cold-induced thermogenesis [GO:0120162] catalytic complex [GO:1902494]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "2,4-dienoyl-CoA reductase (NADPH) activity [GO:0008670]; identical protein binding [GO:0042802]; NADPH binding [GO:0070402]" 0.14751 1.023 LDPTGTFEK 0 0 0 0 0 0 9.16531 9.20587 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q16706 MA2A1_HUMAN "Alpha-mannosidase 2 (EC 3.2.1.114) (Golgi alpha-mannosidase II) (AMan II) (Man II) (Mannosidase alpha class 2A member 1) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)" MAN2A1 MANA2 Homo sapiens (Human) in utero embryonic development [GO:0001701]; liver development [GO:0001889]; lung alveolus development [GO:0048286]; mannose metabolic process [GO:0006013]; mitochondrion organization [GO:0007005]; N-glycan processing [GO:0006491]; positive regulation of neurogenesis [GO:0050769]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; respiratory gaseous exchange by respiratory system [GO:0007585]; retina morphogenesis in camera-type eye [GO:0060042]; vacuole organization [GO:0007033]; viral protein processing [GO:0019082] cis-Golgi network [GO:0005801]; extracellular exosome [GO:0070062]; Golgi medial cisterna [GO:0005797]; Golgi membrane [GO:0000139]; membrane [GO:0016020] "alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing N-glycosyl compounds [GO:0016799]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]" 0.92441 -1.0658 EIAMKISSDIKSQNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.97794 0 0 0 0 0 0 0 0 0 0 0 0 Q16719 KYNU_HUMAN Kynureninase (EC 3.7.1.3) (L-kynurenine hydrolase) KYNU Homo sapiens (Human) 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; L-kynurenine catabolic process [GO:0097053]; NAD biosynthetic process [GO:0009435]; quinolinate biosynthetic process [GO:0019805]; response to type II interferon [GO:0034341]; response to vitamin B6 [GO:0034516]; tryptophan catabolic process [GO:0006569]; tryptophan catabolic process to kynurenine [GO:0019441] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] 3-hydroxykynureninase activity [GO:0061981]; kynureninase activity [GO:0030429]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170] 0 16.285 IEDILEVIEK 0 0 0 0 0 0 0 8.90641 8.65768 9.70496 9.49452 9.37495 0 0 0 10.0945 10.6594 9.24203 0 0 9.72508 0 0 0 0 0 0 Q16720 AT2B3_HUMAN Plasma membrane calcium-transporting ATPase 3 (PMCA3) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3) ATP2B3 Homo sapiens (Human) calcium ion export across plasma membrane [GO:1990034]; monoatomic ion transmembrane transport [GO:0034220]; regulation of cardiac conduction [GO:1903779]; regulation of cytosolic calcium ion concentration [GO:0051480] extracellular vesicle [GO:1903561]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; parallel fiber [GO:1990032]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; calcium ion transmembrane transporter activity [GO:0015085]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; P-type calcium transporter activity [GO:0005388]; P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration [GO:1905056]; PDZ domain binding [GO:0030165] 0.9165 -0.83864 GLNRIQTQIR 0 0 0 0 10.3726 0 0 0 0 10.751 10.69 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q16740 CLPP_HUMAN "ATP-dependent Clp protease proteolytic subunit, mitochondrial (EC 3.4.21.92) (Endopeptidase Clp)" CLPP Homo sapiens (Human) membrane protein proteolysis [GO:0033619]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603] endopeptidase Clp complex [GO:0009368]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252] 0.95004 -1.3838 QLYNIYAK 9.0271 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q16760 DGKD_HUMAN Diacylglycerol kinase delta (DAG kinase delta) (EC 2.7.1.107) (130 kDa diacylglycerol kinase) (Diglyceride kinase delta) (DGK-delta) DGKD KIAA0145 Homo sapiens (Human) diacylglycerol metabolic process [GO:0046339]; endocytosis [GO:0006897]; epidermal growth factor receptor signaling pathway [GO:0007173]; intracellular signal transduction [GO:0035556]; lipid phosphorylation [GO:0046834]; negative regulation of protein kinase C signaling [GO:0090038]; phosphatidic acid biosynthetic process [GO:0006654]; platelet activation [GO:0030168]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; protein transport [GO:0015031]; response to organic substance [GO:0010033]; signal transduction [GO:0007165] clathrin-coated pit [GO:0005905]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; diacylglycerol binding [GO:0019992]; diacylglycerol kinase activity [GO:0004143]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803] 0.92158 -0.93406 IAQCRTVK 10.3498 0 0 0 0 0 0 0 0 0 0 0 10.4969 0 0 0 0 0 0 0 9.45734 0 0 0 0 0 10.4864 Q16778 H2B2E_HUMAN Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q) H2BC21 H2BFQ HIST2H2BE Homo sapiens (Human) antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response in mucosa [GO:0002227]; nucleosome assembly [GO:0006334] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634] DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; structural constituent of chromatin [GO:0030527] 0.053942 1.3985 AMGIMNSFVNDIFER 0 9.08281 10.1454 0 0 0 0 0 0 0 0 8.86375 0 0 0 0 0 0 0 0 0 0 0 0 10.438 0 0 Q16787 LAMA3_HUMAN Laminin subunit alpha-3 (Epiligrin 170 kDa subunit) (E170) (Epiligrin subunit alpha) (Kalinin subunit alpha) (Laminin-5 subunit alpha) (Laminin-6 subunit alpha) (Laminin-7 subunit alpha) (Nicein subunit alpha) LAMA3 LAMNA Homo sapiens (Human) cell-cell adhesion [GO:0098609]; endodermal cell differentiation [GO:0035987]; epidermis development [GO:0008544]; hemidesmosome assembly [GO:0031581]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995] adherens junction [GO:0005912]; basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; hemidesmosome [GO:0030056]; laminin-3 complex [GO:0005608]; laminin-5 complex [GO:0005610] signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198] 0.96864 -3.3569 CKPCSCGRR 0 0 0 9.61478 10.4269 9.30367 9.91666 8.53236 0 11.6285 12.2374 10.6574 0 9.09376 0 0 0 0 0 0 0 0 0 0 0 10.7479 0 Q16795 NDUA9_HUMAN "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (Complex I-39kD) (CI-39kD) (NADH-ubiquinone oxidoreductase 39 kDa subunit)" NDUFA9 NDUFS2L Homo sapiens (Human) "aerobic respiration [GO:0009060]; circadian rhythm [GO:0007623]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]; sodium ion transport [GO:0006814]; ubiquinone-6 biosynthetic process [GO:1901006]" mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex I [GO:0005747]; mitochondrion [GO:0005739]; nucleus [GO:0005634] NADH dehydrogenase (ubiquinone) activity [GO:0008137]; NADH dehydrogenase activity [GO:0003954]; protein-containing complex binding [GO:0044877] 0.92392 -1.0457 MGSQVIIPYRCDK 0 0 0 0 8.68342 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q16799 RTN1_HUMAN Reticulon-1 (Neuroendocrine-specific protein) RTN1 NSP Homo sapiens (Human) brain development [GO:0007420]; endoplasmic reticulum tubular network formation [GO:0071787]; negative regulation of amyloid-beta formation [GO:1902430]; neuron differentiation [GO:0030182] dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; postsynaptic density [GO:0014069] 0.49658 0.61591 SVLQAVQK 0 0 0 0 0 0 0 0 0 0 0 0 0 11.6554 0 0 0 0 0 0 0 0 0 0 0 0 0 Q16819 MEP1A_HUMAN Meprin A subunit alpha (EC 3.4.24.18) (Endopeptidase-2) (N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha) MEP1A Homo sapiens (Human) epidermal growth factor receptor ligand maturation [GO:0038004]; signaling receptor ligand precursor processing [GO:0140448] extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; meprin A complex [GO:0017090]; plasma membrane [GO:0005886] metallodipeptidase activity [GO:0070573]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270] 0.57443 0.47515 STCILFFTLLFAHIAAVPIK 0 0 8.85639 0 0 0 0 0 9.03969 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q16820 MEP1B_HUMAN Meprin A subunit beta (EC 3.4.24.63) (Endopeptidase-2) (Meprin B) (N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta) MEP1B Homo sapiens (Human) inflammatory response [GO:0006954]; proteolysis [GO:0006508]; toxin transport [GO:1901998] extracellular region [GO:0005576]; meprin A complex [GO:0017090]; plasma membrane [GO:0005886] identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270] 0.84898 0.1133 GSGCWSSVGNR 9.0731 0 0 0 0 0 0 0 0 0 10.5945 0 0 0 0 0 0 9.60368 0 0 0 0 0 0 0 0 0 Q16821 PPR3A_HUMAN Protein phosphatase 1 regulatory subunit 3A (Protein phosphatase 1 glycogen-associated regulatory subunit) (Protein phosphatase type-1 glycogen targeting subunit) (RG1) PPP1R3A PP1G Homo sapiens (Human) glycogen metabolic process [GO:0005977]; regulation of glycogen biosynthetic process [GO:0005979] membrane [GO:0016020]; protein phosphatase type 1 complex [GO:0000164] glycogen binding [GO:2001069]; protein phosphatase 1 binding [GO:0008157] 0.96893 -3.8786 DVNREHDEHNEK 0 0 0 12.351 0 0 0 0 0 9.55564 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q16822 PCKGM_HUMAN "Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PEPCK-M) (EC 4.1.1.32)" PCK2 PEPCK2 Homo sapiens (Human) cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; NADH oxidation [GO:0006116]; oxaloacetate metabolic process [GO:0006107]; positive regulation of insulin secretion [GO:0032024]; propionate catabolic process [GO:0019543]; response to lipopolysaccharide [GO:0032496]; response to starvation [GO:0042594] cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] GTP binding [GO:0005525]; manganese ion binding [GO:0030145]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611] 0.9627 -2.0921 SESTAAAEHKGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.40501 0 0 0 0 0 0 Q16832 DDR2_HUMAN "Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)" DDR2 NTRKR3 TKT TYRO10 Homo sapiens (Human) biomineral tissue development [GO:0031214]; cell adhesion [GO:0007155]; cellular response to angiotensin [GO:1904385]; cellular response to hypoxia [GO:0071456]; cellular response to transforming growth factor beta stimulus [GO:0071560]; chondrocyte proliferation [GO:0035988]; collagen fibril organization [GO:0030199]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; endochondral bone growth [GO:0003416]; negative regulation of apoptotic process [GO:0043066]; negative regulation of hydrogen peroxide-mediated programmed cell death [GO:1901299]; negative regulation of kinase activity [GO:0033673]; negative regulation of necrotic cell death [GO:0060547]; ossification [GO:0001503]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of hepatic stellate cell activation [GO:2000491]; positive regulation of hepatic stellate cell proliferation [GO:1904899]; positive regulation of kinase activity [GO:0033674]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron projection development [GO:0010976]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; positive regulation of wound healing [GO:0090303]; protein autophosphorylation [GO:0046777]; regulation of bone mineralization [GO:0030500]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of tissue remodeling [GO:0034103]; response to muscle stretch [GO:0035994]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] ATP binding [GO:0005524]; collagen binding [GO:0005518]; protein tyrosine kinase collagen receptor activity [GO:0038062]; transmembrane receptor protein tyrosine kinase activity [GO:0004714] 0.95539 -1.5964 DLEPPIVAR 0 0 0 0 0 0 8.39348 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q16836 HCDH_HUMAN "Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HCDH) (EC 1.1.1.35) (Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase) (Short-chain 3-hydroxyacyl-CoA dehydrogenase)" HADH HAD HAD1 HADHSC SCHAD Homo sapiens (Human) fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of insulin secretion [GO:0050796]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to xenobiotic stimulus [GO:0009410] cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; transferase activity [GO:0016740] 0.95249 -1.4921 LYERGDASK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.22156 0 0 0 0 0 0 Q16842 SIA4B_HUMAN "CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 (Alpha 2,3-ST 2) (Beta-galactoside alpha-2,3-sialyltransferase 2) (EC 2.4.3.4) (Gal-NAc6S) (Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase) (Monosialoganglioside sialyltransferase) (EC 2.4.3.2) (ST3Gal II) (ST3GalII) (ST3GalA.2) (Sialyltransferase 4B) (SIAT4-B)" ST3GAL2 SIAT4B Homo sapiens (Human) ganglioside biosynthetic process via lactosylceramide [GO:0010706]; globoside biosynthetic process via lactosylceramide [GO:0010707]; glycolipid biosynthetic process [GO:0009247]; glycoprotein biosynthetic process [GO:0009101]; keratan sulfate biosynthetic process [GO:0018146]; lipid glycosylation [GO:0030259]; O-glycan processing [GO:0016266]; oligosaccharide biosynthetic process [GO:0009312]; protein glycosylation [GO:0006486]; protein sialylation [GO:1990743]; sialylation [GO:0097503]; viral protein processing [GO:0019082] extracellular region [GO:0005576]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; membrane [GO:0016020] "beta-galactoside (CMP) alpha-2,3-sialyltransferase activity [GO:0003836]; monosialoganglioside sialyltransferase activity [GO:0047288]; protein homodimerization activity [GO:0042803]; sialyltransferase activity [GO:0008373]" 0.56584 0.49054 GNWHHYWENNR 8.65342 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3749 0 Q16849 PTPRN_HUMAN Receptor-type tyrosine-protein phosphatase-like N (R-PTP-N) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3) (PTP IA-2) [Cleaved into: ICA512-N-terminal fragment (ICA512-NTF); ICA512-transmembrane fragment (ICA512-TMF); ICA512-cleaved cytosolic fragment (ICA512-CCF)] PTPRN ICA3 ICA512 Homo sapiens (Human) dense core granule maturation [GO:1990502]; insulin secretion [GO:0030073]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; luteinization [GO:0001553]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type B pancreatic cell proliferation [GO:1904692]; regulation of secretion [GO:0051046]; response to reactive oxygen species [GO:0000302] axon terminus [GO:0043679]; endosome [GO:0005768]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; synapse [GO:0045202]; transport vesicle membrane [GO:0030658] spectrin binding [GO:0030507]; transcription factor binding [GO:0008134]; ubiquitin-like protein ligase binding [GO:0044389] 0.848 0.15775 VESSPSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4211 0 0 Q16851 UGPA_HUMAN UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (UDP-glucose pyrophosphorylase) (UDPGP) (UGPase) UGP2 UGP1 Homo sapiens (Human) brain development [GO:0007420]; glucose 1-phosphate metabolic process [GO:0019255]; glycogen biosynthetic process [GO:0005978]; glycogen metabolic process [GO:0005977]; UDP-glucose metabolic process [GO:0006011] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634] glucose binding [GO:0005536]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; pyrimidine ribonucleotide binding [GO:0032557]; UTP:glucose-1-phosphate uridylyltransferase activity [GO:0003983] 0 3.0318 EFPTVPLVK 0 0 0 11.4246 11.7401 11.7583 0 0 0 0 0 0 0 0 0 12.4079 0 11.9367 0 0 0 8.19052 0 0 0 0 10.7891 Q16875 F263_HUMAN "6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (6PF-2-K/Fru-2,6-P2ase 3) (PFK/FBPase 3) (6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme) (Renal carcinoma antigen NY-REN-56) (iPFK-2) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]" PFKFB3 Homo sapiens (Human) "brain development [GO:0007420]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]" cytosol [GO:0005829]; nucleoplasm [GO:0005654] "6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]" 0.84732 0.13077 IVYYLMNIHVQPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.77198 0 0 0 Q16877 F264_HUMAN "6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (6PF-2-K/Fru-2,6-P2ase 4) (PFK/FBPase 4) (6PF-2-K/Fru-2,6-P2ase testis-type isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]" PFKFB4 Homo sapiens (Human) "fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]" cytosol [GO:0005829] "6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]" 0.96829 -3.6132 DLKVWTSQMK 0 0 0 0 0 0 0 0 16.1514 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q16878 CDO1_HUMAN Cysteine dioxygenase type 1 (EC 1.13.11.20) (Cysteine dioxygenase type I) (CDO) (CDO-I) CDO1 Homo sapiens (Human) cysteine metabolic process [GO:0006534]; inflammatory response [GO:0006954]; L-cysteine catabolic process [GO:0019448]; lactation [GO:0007595]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; sulfur amino acid biosynthetic process [GO:0000097]; taurine biosynthetic process [GO:0042412] cytosol [GO:0005829] cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; nickel cation binding [GO:0016151]; zinc ion binding [GO:0008270] 0.87657 -0.0013147 NLVDQGNGK 0 0 0 0 0 0 0 11.5901 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q16880 CGT_HUMAN 2-hydroxyacylsphingosine 1-beta-galactosyltransferase (EC 2.4.1.47) (Ceramide UDP-galactosyltransferase) (Cerebroside synthase) (UDP-galactose-ceramide galactosyltransferase) UGT8 CGT UGT4 Homo sapiens (Human) central nervous system development [GO:0007417]; cytoskeleton organization [GO:0007010]; galactosylceramide biosynthetic process [GO:0006682]; glycosphingolipid metabolic process [GO:0006687]; neuron projection morphogenesis [GO:0048812]; paranodal junction assembly [GO:0030913]; peripheral nervous system development [GO:0007422]; protein localization to paranode region of axon [GO:0002175] endoplasmic reticulum [GO:0005783]; plasma membrane [GO:0005886] "2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity [GO:0003851]; N-acylsphingosine galactosyltransferase activity [GO:0047263]; UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity [GO:0008489]" 0.96188 -2.4661 AQKLSEIHK 0 0 0 8.76378 8.88503 9.07898 8.89376 8.87086 0 9.34988 9.08044 8.99588 9.00739 9.07577 0 0 0 0 0 0 0 0 0 0 0 0 0 Q16881 TRXR1_HUMAN "Thioredoxin reductase 1, cytoplasmic (TR) (EC 1.8.1.9) (Gene associated with retinoic and interferon-induced mortality 12 protein) (GRIM-12) (Gene associated with retinoic and IFN-induced mortality 12 protein) (KM-102-derived reductase-like factor) (Peroxidase TXNRD1) (EC 1.11.1.2) (Thioredoxin reductase TR1)" TXNRD1 GRIM12 KDRF Homo sapiens (Human) cell population proliferation [GO:0008283]; cell redox homeostasis [GO:0045454]; mesoderm formation [GO:0001707]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] FAD binding [GO:0071949]; identical protein binding [GO:0042802]; NADPH peroxidase activity [GO:0050137]; thioredoxin-disulfide reductase activity [GO:0004791] 0.96901 -3.477 EAAQYGK 8.68131 0 8.49773 0 0 0 8.89797 9.16247 9.07256 9.19219 9.0549 9.26629 0 0 0 8.1333 0 0 8.31642 0 0 0 0 0 0 0 8.05707 Q16891 MIC60_HUMAN MICOS complex subunit MIC60 (Cell proliferation-inducing gene 4/52 protein) (Mitochondrial inner membrane protein) (Mitofilin) (p87/89) IMMT HMP MIC60 MINOS2 PIG4 PIG52 Homo sapiens (Human) cristae formation [GO:0042407]; inner mitochondrial membrane organization [GO:0007007]; mitochondrial calcium ion homeostasis [GO:0051560]; neuron cellular homeostasis [GO:0070050] membrane [GO:0016020]; MIB complex [GO:0140275]; MICOS complex [GO:0061617]; mitochondrial crista junction [GO:0044284]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; SAM complex [GO:0001401] RNA binding [GO:0003723] 0 4.4755 AVDEAADALLK 0 0 10.5894 0 0 0 0 0 0 0 0 0 0 9.21011 0 0 0 0 10.2717 0 0 0 0 9.91677 0 10.0712 10.269 Q17R31 TATD3_HUMAN Putative deoxyribonuclease TATDN3 (EC 3.1.21.-) TATDN3 Homo sapiens (Human) nucleus [GO:0005634] metal ion binding [GO:0046872]; nuclease activity [GO:0004518] 0.86918 0.04481 AGYFFSIPPSIIR 0 0 0 0 9.61489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q17R55 F187B_HUMAN Protein FAM187B (Transmembrane protein 162) FAM187B TMEM162 Homo sapiens (Human) membrane [GO:0016020] 0.87099 0.063566 ANDTPLTWESQLSGQDFTTFLDPSTGGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6085 10.6494 0 0 0 0 0 0 0 0 0 Q17R60 IMPG1_HUMAN Interphotoreceptor matrix proteoglycan 1 (Interphotoreceptor matrix proteoglycan of 150 kDa) (IPM-150) (Sialoprotein associated with cones and rods) IMPG1 IPM150 SPACR Homo sapiens (Human) extracellular matrix organization [GO:0030198]; visual perception [GO:0007601] extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; interphotoreceptor matrix [GO:0033165]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750] chondroitin sulfate binding [GO:0035374]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; hyaluronic acid binding [GO:0005540] 0.75832 0.30058 DISINIYHSETK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.24517 0 0 0 0 0 9.12482 0 0 0 Q17R89 RHG44_HUMAN Rho GTPase-activating protein 44 (NPC-A-10) (Rho-type GTPase-activating protein RICH2) (RhoGAP interacting with CIP4 homologs protein 2) (RICH-2) ARHGAP44 KIAA0672 RICH2 Homo sapiens (Human) "exocytosis [GO:0006887]; modification of dendritic spine [GO:0098886]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of filopodium assembly [GO:0051490]; negative regulation of Rac protein signal transduction [GO:0035021]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive regulation of GTPase activity [GO:0043547]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of GTPase activity [GO:0043087]; regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0099152]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]" cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; leading edge membrane [GO:0031256]; postsynaptic density [GO:0014069]; presynaptic active zone [GO:0048786]; recycling endosome [GO:0055037] GTPase activator activity [GO:0005096]; phospholipid binding [GO:0005543]; small GTPase binding [GO:0031267] 0.93206 -1.2663 IQSMGVRVMDTNWVARR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.3516 0 0 0 0 0 0 0 0 Q17R98 ZN827_HUMAN Zinc finger protein 827 ZNF827 Homo sapiens (Human) chromatin remodeling [GO:0006338]; establishment of protein localization to telomere [GO:0070200]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of shelterin complex assembly [GO:1904791]; regulation of gene expression [GO:0010468]; telomere maintenance [GO:0000723] "chromatin [GO:0000785]; chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]" DNA binding [GO:0003677]; metal ion binding [GO:0046872]; NuRD complex binding [GO:0120325] 0.89931 -0.6878 LAEKQEQNDQYTPSNR 0 0 0 0 0 0 0 0 0 9.90025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4617 Q17RC7 EX3L4_HUMAN Exocyst complex component 3-like protein 4 EXOC3L4 C14orf73 Homo sapiens (Human) exocyst localization [GO:0051601]; exocytosis [GO:0006887] exocyst [GO:0000145] SNARE binding [GO:0000149] 0.88424 -0.12214 DGTRLGLGSLRQAFSR 0 0 0 0 0 0 0 0 0 10.4266 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q17RD7 SYT16_HUMAN Synaptotagmin-16 (Chr14Syt) (Synaptotagmin 14-like protein) (Synaptotagmin XIV-related protein) SYT16 STREP14 SYT14L SYT14R Homo sapiens (Human) identical protein binding [GO:0042802]; phospholipid binding [GO:0005543] 0.92218 -1.1283 NLAVNRAPDTYGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2235 0 0 0 0 0 0 0 0 Q17RN3 FA98C_HUMAN Protein FAM98C FAM98C Homo sapiens (Human) tRNA-splicing ligase complex [GO:0072669] 0.96245 -2.5417 ADLSCLVPATSVAVRR 10.0669 0 0 0 0 0 10.2439 0 0 0 0 9.96346 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q17RP2 TIGD6_HUMAN Tigger transposable element-derived protein 6 TIGD6 Homo sapiens (Human) nucleus [GO:0005634] DNA binding [GO:0003677] 0.91443 -0.7816 VVGAVDSGKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.57338 0 0 0 0 0 0 0 0 Q17RQ9 NKPD1_HUMAN NTPase KAP family P-loop domain-containing protein 1 NKPD1 Homo sapiens (Human) membrane [GO:0016020] 0.88393 -0.20629 IDDEAARR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6691 0 9.1145 Q17RR3 LIPR3_HUMAN Pancreatic lipase-related protein 3 (PL-RP3) (EC 3.1.1.3) PNLIPRP3 Homo sapiens (Human) lipid catabolic process [GO:0016042] extracellular region [GO:0005576] triglyceride lipase activity [GO:0004806] 0.77459 0.26553 LGAEMVINTSGK 0 0 0 0 0 0 0 0 0 0 9.05607 0 0 0 0 0 0 0 0 0 0 9.40137 0 0 0 0 0 Q17RS7 GEN_HUMAN Flap endonuclease GEN homolog 1 (EC 3.1.-.-) GEN1 Homo sapiens (Human) double-strand break repair via homologous recombination [GO:0000724]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; regulation of centrosome duplication [GO:0010824]; replication fork processing [GO:0031297]; resolution of mitotic recombination intermediates [GO:0071140]; resolution of recombination intermediates [GO:0071139] centrosome [GO:0005813]; nucleoplasm [GO:0005654] 5'-flap endonuclease activity [GO:0017108]; crossover junction DNA endonuclease activity [GO:0008821]; four-way junction DNA binding [GO:0000400]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803] 0.91497 -0.77754 KVDMQTTRK 0 0 0 0 0 0 0 0 0 0 0 12.0404 0 0 0 0 0 9.81844 0 0 0 0 0 0 0 0 0 Q17RW2 COOA1_HUMAN Collagen alpha-1(XXIV) chain COL24A1 Homo sapiens (Human) extracellular matrix organization [GO:0030198] collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] extracellular matrix structural constituent [GO:0005201] 0.96216 -2.5541 GAQGDQGPCGDPGLK 0 0 0 0 0 0 0 0 9.34753 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.63679 0 Q17RY0 CPEB4_HUMAN Cytoplasmic polyadenylation element-binding protein 4 (CPE-BP4) (CPE-binding protein 4) (hCPEB-4) CPEB4 KIAA1673 Homo sapiens (Human) cellular response to amino acid stimulus [GO:0071230]; cellular response to decreased oxygen levels [GO:0036294]; cellular response to glucose starvation [GO:0042149]; ionotropic glutamate receptor signaling pathway [GO:0035235]; negative regulation of cytoplasmic translation [GO:2000766]; negative regulation of neuron apoptotic process [GO:0043524]; response to ischemia [GO:0002931] cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; growth cone [GO:0030426]; messenger ribonucleoprotein complex [GO:1990124]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; synapse [GO:0045202] "metal ion binding [GO:0046872]; mRNA 3'-UTR binding [GO:0003730]; mRNA regulatory element binding translation repressor activity [GO:0000900]; ribosome binding [GO:0043022]; RNA binding [GO:0003723]; translation factor activity, RNA binding [GO:0008135]" 0.8906 -0.47952 AKSQQQEQQDPLEK 10.5316 0 10.4829 0 0 0 9.32701 0 0 0 0 0 0 8.81826 0 0 9.88417 0 0 0 0 0 0 0 0 0 0 Q19T08 ECSCR_HUMAN Endothelial cell-specific chemotaxis regulator (Apoptosis regulator through modulating IAP expression) (ARIA) (Endothelial cell-specific molecule 2) ECSCR ECSM2 Homo sapiens (Human) angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; negative regulation of angiogenesis [GO:0016525]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of proteasomal protein catabolic process [GO:1901800] cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] 0.91362 -0.75393 NINMNNGKQSLSAEK 0 0 11.0451 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q1A5X7 WHAL1_HUMAN "Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1 (WAS protein homolog associated with actin, Golgi membranes and microtubules pseudogene 3) (WAS protein homology region 2 domain-containing protein 1-like protein 1) (WH2 domain-containing protein 1-like protein 1) (WHDC1-like protein 1)" WHAMMP3 WHAMML1 WHDC1L1 Homo sapiens (Human) 0.91384 -0.801 HLPQLGMQKEMEQDVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.3233 0 0 0 0 0 0 0 0 0 0 0 Q1AE95 T183B_HUMAN Putative transmembrane protein 183BP (Transmembrane protein 183B pseudogene) TMEM183BP C1orf37-dup TMEM183B Homo sapiens (Human) regulation of protein stability [GO:0031647] membrane [GO:0016020]; SCF ubiquitin ligase complex [GO:0019005] 0.88218 -0.07138 AVANAVR 0 0 10.3081 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.54144 0 9.2078 0 0 0 0 0 0 0 Q1ED39 KNOP1_HUMAN Lysine-rich nucleolar protein 1 (Protein FAM191A) (Testis-specific gene 118 protein) KNOP1 C16orf88 FAM191A TSG118 Homo sapiens (Human) nucleolus [GO:0005730] RNA binding [GO:0003723] 0.96692 -2.3233 EPETRYSVLNNDDYFADVSPLR 0 0 0 0 0 0 9.60838 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.18225 0 0 0 0 Q1KMD3 HNRL2_HUMAN Heterogeneous nuclear ribonucleoprotein U-like protein 2 (Scaffold-attachment factor A2) (SAF-A2) HNRNPUL2 HNRPUL2 Homo sapiens (Human) membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; synapse [GO:0045202] RNA binding [GO:0003723] 0.9564 -1.5426 ANFSLPEK 0 10.451 10.338 0 0 0 0 10.1936 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q1L5Z9 LONF2_HUMAN LON peptidase N-terminal domain and RING finger protein 2 (Neuroblastoma apoptosis-related protease) (RING finger protein 192) LONRF2 RNF192 Homo sapiens (Human) cytoplasm [GO:0005737] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630] 0.61099 0.43285 LGDALAR 12.0642 0 0 0 0 0 0 0 0 0 0 0 0 10.7044 0 11.2764 0 10.5113 0 0 0 0 0 0 0 0 0 Q1MSJ5 CSPP1_HUMAN Centrosome and spindle pole-associated protein 1 CSPP1 CSPP Homo sapiens (Human) positive regulation of cell division [GO:0051781]; positive regulation of cytokinesis [GO:0032467] centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; microtubule [GO:0005874]; spindle [GO:0005819]; spindle pole [GO:0000922] 0.96977 -5.3946 EEKEEYEAK 0 0 0 0 0 0 0 0 9.33405 8.78342 0 0 0 0 9.83542 0 8.25404 0 0 0 0 0 0 0 0 9.25293 0 Q1MX18 INSC_HUMAN Protein inscuteable homolog INSC Homo sapiens (Human) apical protein localization [GO:0045176]; asymmetric cell division [GO:0008356]; cell differentiation [GO:0030154]; establishment of mitotic spindle orientation [GO:0000132]; nervous system development [GO:0007399]; regulation of asymmetric cell division [GO:0009786]; regulation of protein stability [GO:0031647] apical cortex [GO:0045179]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] cytoskeletal anchor activity [GO:0008093]; protein domain specific binding [GO:0019904]; protein-macromolecule adaptor activity [GO:0030674] 0.96179 -2.4663 EMGEIEK 0 0 0 0 0 0 0 0 0 0 0 8.81006 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q1RMZ1 SAMTR_HUMAN S-adenosylmethionine sensor upstream of mTORC1 (Probable methyltransferase BMT2 homolog) (EC 2.1.1.-) BMT2 C7orf60 SAMTOR Homo sapiens (Human) cellular response to amino acid starvation [GO:0034198]; methylation [GO:0032259]; negative regulation of TORC1 signaling [GO:1904262] cytosol [GO:0005829] methyltransferase activity [GO:0008168]; S-adenosyl-L-methionine binding [GO:1904047] 0.36923 0.73289 EHCEDEETLCEYAVAMKNLADNHWAK 10.1173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q1X8D7 LRC36_HUMAN Leucine-rich repeat-containing protein 36 (ROR gamma-binding protein 70) LRRC36 RORBP70 Homo sapiens (Human) 0.35985 0.75001 ALLPPEK 0 0 0 0 0 0 0 0 11.7568 0 0 0 10.2417 0 0 0 0 0 11.2956 12.0027 0 0 0 0 0 0 0 Q1XH10 SKDA1_HUMAN SKI/DACH domain-containing protein 1 (Protein DLN-1) SKIDA1 C10orf140 DLN1 Homo sapiens (Human) 0.93222 -1.2642 NIPRTTVHKR 9.07767 8.86223 8.61839 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q24JQ0 TM241_HUMAN Transmembrane protein 241 TMEM241 C18orf45 Homo sapiens (Human) Golgi apparatus [GO:0005794]; membrane [GO:0016020] antiporter activity [GO:0015297] 0.87903 0.018983 SLVGLTFCTCYLASYLTNK 0 0 0 0 14.6698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q29980 MICB_HUMAN MHC class I polypeptide-related sequence B (MIC-B) MICB PERB11.2 Homo sapiens (Human) "adaptive immune response [GO:0002250]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent [GO:0002486]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; gamma-delta T cell activation [GO:0046629]; immune response [GO:0006955]; immune response-activating cell surface receptor signaling pathway [GO:0002429]; killing of cells of another organism [GO:0031640]; negative regulation of defense response to virus by host [GO:0050689]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to retinoic acid [GO:0032526]" cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] natural killer cell lectin-like receptor binding [GO:0046703]; peptide antigen binding [GO:0042605]; signaling receptor binding [GO:0005102] 0.9396 -1.3195 AQTLAMNVTNFWK 0 10.4728 0 9.8955 9.91916 9.90548 0 0 0 0 0 0 10.0393 10.1192 0 11.1653 0 0 0 0 0 0 0 0 0 0 0 Q29983 MICA_HUMAN MHC class I polypeptide-related sequence A (MIC-A) MICA PERB11.1 Homo sapiens (Human) "antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent [GO:0002486]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; DNA damage response [GO:0006974]; gamma-delta T cell activation [GO:0046629]; immune response [GO:0006955]; immune response to tumor cell [GO:0002418]; killing of cells of another organism [GO:0031640]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; response to heat [GO:0009408]; T cell mediated cytotoxicity [GO:0001913]" cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] natural killer cell lectin-like receptor binding [GO:0046703]; peptide antigen binding [GO:0042605]; signaling receptor binding [GO:0005102] 0.8825 -0.10248 DLRMTLAHIKDQK 0 0 0 0 0 0 0 0 0 0 9.94481 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q29RF7 PDS5A_HUMAN Sister chromatid cohesion protein PDS5 homolog A (Cell proliferation-inducing gene 54 protein) (Sister chromatid cohesion protein 112) (SCC-112) PDS5A KIAA0648 PDS5 PIG54 Homo sapiens (Human) cell division [GO:0051301]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of DNA replication [GO:0008156] "chromatin [GO:0000785]; chromosome [GO:0005694]; chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]" 0.96939 -3.1362 FFTQPEKDFCNDK 0 0 0 0 0 0 0 0 0 0 0 0 9.01153 0 0 0 0 0 0 9.47135 0 0 0 0 0 0 0 Q2I0M5 RSPO4_HUMAN R-spondin-4 (Roof plate-specific spondin-4) (hRspo4) RSPO4 C20orf182 Homo sapiens (Human) nail development [GO:0035878]; positive regulation of Wnt signaling pathway [GO:0030177]; Wnt signaling pathway [GO:0016055] extracellular region [GO:0005576] heparin binding [GO:0008201] 0.94674 -1.3513 AGHEEAATCQVLSESR 10.7708 9.3384 0 9.258 0 0 9.38137 9.33965 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q2KHR2 RFX7_HUMAN DNA-binding protein RFX7 (Regulatory factor X 7) (Regulatory factor X domain-containing protein 2) RFX7 RFXDC2 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.78699 0.25803 NTLEEHPETSLPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.87015 0 0 0 9.98584 0 0 0 0 0 0 0 Q2KHR3 QSER1_HUMAN Glutamine and serine-rich protein 1 QSER1 Homo sapiens (Human) chromosome [GO:0005694] 0.95984 -1.7493 GHFSETNQHDSK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9259 0 0 0 0 0 0 0 0 0 9.13681 0 0 0 Q2KHT3 CL16A_HUMAN Protein CLEC16A (C-type lectin domain family 16 member A) CLEC16A KIAA0350 Homo sapiens (Human) autophagy [GO:0006914]; cellular response to starvation [GO:0009267]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; negative regulation of autophagosome maturation [GO:1901097]; positive regulation of TORC1 signaling [GO:1904263]; regulation of autophagosome maturation [GO:1901096] cytosol [GO:0005829]; endolysosome membrane [GO:0036020]; Golgi apparatus [GO:0005794]; vesicle [GO:0031982] 0.91986 -0.90122 NMFVFFLNILR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1472 Q2KHT4 GSG1_HUMAN Germ cell-specific gene 1 protein GSG1 UNQ709/PRO1360 Homo sapiens (Human) endoplasmic reticulum membrane [GO:0005789]; plasma membrane [GO:0005886] 0.95912 -1.7161 MAKMELSK 0 0 0 0 0 0 0 0 0 0 0 0 0 8.29416 0 0 0 0 0 0 0 0 0 0 0 0 0 Q2KJY2 KI26B_HUMAN Kinesin-like protein KIF26B KIF26B Homo sapiens (Human) establishment of cell polarity [GO:0030010]; microtubule-based movement [GO:0007018]; positive regulation of cell-cell adhesion [GO:0022409]; ureteric bud invasion [GO:0072092] cytoplasm [GO:0005737]; microtubule [GO:0005874] ATP binding [GO:0005524]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777] 0.95924 -1.7116 EGPELPASK 0 0 11.4436 0 0 0 0 0 0 0 9.12601 0 0 0 0 0 0 0 8.63514 8.41083 8.59081 0 8.50934 0 10.2662 0 0 Q2LD37 BLTP1_HUMAN Bridge-like lipid transfer protein family member 1 (Fragile site-associated protein) BLTP1 FSA KIAA1109 KIAA1371 TWEEK Homo sapiens (Human) endocytic recycling [GO:0032456]; endosomal transport [GO:0016197]; intermembrane lipid transfer [GO:0120009]; phagocytosis [GO:0006909]; regulation of cell growth [GO:0001558]; regulation of epithelial cell differentiation [GO:0030856]; synaptic vesicle endocytosis [GO:0048488] endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-plasma membrane contact site [GO:0140268]; membrane [GO:0016020]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; presynapse [GO:0098793] phosphatidylethanolamine transfer activity [GO:1904121] 0.96921 -5.7674 AEYKMGRMR 0 0 0 0 0 11.5868 0 9.75674 0 0 11.9844 0 0 0 0 13.1152 0 0 0 0 0 0 0 0 0 0 0 Q2M1K9 ZN423_HUMAN Zinc finger protein 423 (Olf1/EBF-associated zinc finger protein) (hOAZ) (Smad- and Olf-interacting zinc finger protein) ZNF423 KIAA0760 NPHP14 OAZ Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of DNA-templated transcription [GO:0045892]; nervous system development [GO:0007399]; Notch signaling pathway [GO:0007219]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of DNA-templated transcription [GO:0045893]; protein localization to cilium [GO:0061512]; regulation of DNA-templated transcription [GO:0006355] nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]" 0.88477 -0.14103 TSRALEDRNSVTSQEER 10.9654 0 0 0 0 0 0 0 0 0 10.6162 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q2M1P5 KIF7_HUMAN Kinesin-like protein KIF7 KIF7 UNQ340/PRO539 Homo sapiens (Human) microtubule-based movement [GO:0007018]; negative regulation of smoothened signaling pathway [GO:0045879]; positive regulation of smoothened signaling pathway [GO:0045880] ciliary basal body [GO:0036064]; ciliary tip [GO:0097542]; cilium [GO:0005929]; cytoplasm [GO:0005737]; kinesin complex [GO:0005871]; microtubule [GO:0005874] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777] 0.96714 -3.7583 ALLCKYFDK 0 0 9.51045 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.00977 0 0 9.92773 10.3437 0 0 Q2M243 CCD27_HUMAN Coiled-coil domain-containing protein 27 CCDC27 Homo sapiens (Human) 0.96911 -3.0614 EALKMQLKCLLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.93614 9.96838 0 0 0 0 10.2648 10.3157 Q2M296 MTHSD_HUMAN Methenyltetrahydrofolate synthase domain-containing protein MTHFSD Homo sapiens (Human) cytoplasm [GO:0005737] RNA binding [GO:0003723] 0.59019 0.45779 ELGSVPLR 0 0 11.5234 0 0 0 10.1283 0 10.272 11.9832 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q2M2D7 TBC28_HUMAN TBC1 domain family member 28 TBC1D28 Homo sapiens (Human) 0.87028 0.041488 IIHCIQLDVSHTLQK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8412 0 0 0 0 0 0 0 0 0 0 0 0 0 Q2M2H8 MGAL_HUMAN "Probable maltase-glucoamylase 2 (Maltase-glucoamylase (alpha-glucosidase) pseudogene) [Includes: Glucoamylase (EC 3.2.1.3) (Glucan 1,4-alpha-glucosidase)]" MGAM2 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975] membrane [GO:0016020] "alpha-1,4-glucosidase activity [GO:0004558]; carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]" 0.93976 -1.3006 EIEELYANPR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.85488 0 0 0 0 0 0 0 0 0 0 9.52718 9.94821 0 Q2M2I3 FA83E_HUMAN Protein FAM83E FAM83E Homo sapiens (Human) signal transduction [GO:0007165] protein kinase binding [GO:0019901] 0.4162 0.68282 AGLGGQP 0 0 0 10.4032 10.3085 10.6745 0 0 8.23525 0 10.8701 0 0 0 0 0 8.9909 9.6667 0 0 10.9895 0 0 0 0 0 0 Q2M2I5 K1C24_HUMAN "Keratin, type I cytoskeletal 24 (Cytokeratin-24) (CK-24) (Keratin-24) (K24) (Type I keratin-24)" KRT24 KA24 Homo sapiens (Human) epithelial cell differentiation [GO:0030855]; intermediate filament organization [GO:0045109] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882] structural molecule activity [GO:0005198] 0.87199 0.030678 LAADDFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.53469 0 0 0 0 0 0 0 0 Q2M2W7 CQ058_HUMAN UPF0450 protein C17orf58 C17orf58 Homo sapiens (Human) collagen-containing extracellular matrix [GO:0062023] 0.95187 -1.4279 DAEPGAEPCARACRSDLDER 0 9.00442 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q2M2Z5 KIZ_HUMAN Centrosomal protein kizuna (Polo-like kinase 1 substrate 1) KIZ C20orf19 NCRNA00153 PLK1S1 HT013 Homo sapiens (Human) spindle organization [GO:0007051] cell projection [GO:0042995]; centrosome [GO:0005813]; cytoplasm [GO:0005737] protein kinase binding [GO:0019901] 0.62921 0.40162 EHDNSVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.71679 0 0 0 0 0 0 0 0 0 0 Q2M389 WASC4_HUMAN WASH complex subunit 4 (Strumpellin and WASH-interacting protein) (SWIP) (WASH complex subunit SWIP) WASHC4 KIAA1033 Homo sapiens (Human) endosomal transport [GO:0016197]; endosome organization [GO:0007032]; nuclear envelope budding [GO:0140591]; protein transport [GO:0015031]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315] early endosome membrane [GO:0031901]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; WASH complex [GO:0071203] 0.96279 -2.4435 LIKDIRFFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.64663 0 0 0 0 0 0 0 0 0 0 Q2M3C6 TM266_HUMAN Transmembrane protein 266 (hTMEM266) (HV1-related protein 1) (HsHVRP1) TMEM266 C15orf27 HVRP1 Homo sapiens (Human) cytosol [GO:0005829]; dendrite [GO:0030425]; perikaryon [GO:0043204]; plasma membrane [GO:0005886] protein homodimerization activity [GO:0042803] 0.95923 -1.7161 SLESKEQK 0 0 0 0 0 0 0 0 0 0 10.2174 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q2M3C7 SPKAP_HUMAN A-kinase anchor protein SPHKAP (SPHK1-interactor and AKAP domain-containing protein) (Sphingosine kinase type 1-interacting protein) SPHKAP KIAA1678 SKIP Homo sapiens (Human) cytoplasm [GO:0005737]; mitochondrion [GO:0005739] protein kinase A binding [GO:0051018] 0.90583 -0.72379 GNRPNSTNCIIFEINK 10.925 0 0 0 10.5147 0 0 0 0 0 0 10.8598 0 0 0 0 9.6386 0 0 0 0 0 0 10.3098 0 0 0 Q2M3D2 EX3L2_HUMAN Exocyst complex component 3-like protein 2 (HBV X-transactivated gene 7 protein) (HBV XAg-transactivated protein 7) EXOC3L2 XTP7 Homo sapiens (Human) exocytosis [GO:0006887] exocyst [GO:0000145] 0.91345 -0.76148 QKHVAALLDIRGLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6709 0 0 0 0 9.94818 0 0 Q2M3G0 ABCB5_HUMAN ATP-binding cassette sub-family B member 5 (ABCB5 P-gp) (P-glycoprotein ABCB5) (EC 7.6.2.2) ABCB5 Homo sapiens (Human) cell differentiation [GO:0030154]; eye development [GO:0001654]; regulation of membrane potential [GO:0042391]; transmembrane transport [GO:0055085] plasma membrane [GO:0005886] ABC-type xenobiotic transporter activity [GO:0008559]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]; efflux transmembrane transporter activity [GO:0015562] 0.95918 -1.7615 DAKDFGIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0257 0 Q2M3G4 SHRM1_HUMAN Protein Shroom1 (Apical protein 2) SHROOM1 APXL2 KIAA1960 Homo sapiens (Human) actin filament bundle assembly [GO:0051017]; cell morphogenesis [GO:0000902] adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical plasma membrane [GO:0016324]; cortical actin cytoskeleton [GO:0030864]; microtubule [GO:0005874] actin filament binding [GO:0051015]; myosin II binding [GO:0045159] 0.92172 -0.93758 KELRMSLPAR 0 0 0 0 0 0 0 0 0 0 8.87209 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q2M3T9 HYAL4_HUMAN Hyaluronidase-4 (Hyal-4) (EC 3.2.1.35) (Chondroitin sulfate endo-beta-N-acetylgalactosaminidase) (Chondroitin sulfate hydrolase) (CSHY) (Hyaluronoglucosaminidase-4) HYAL4 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate catabolic process [GO:0030207]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214] cell surface [GO:0009986]; membrane [GO:0016020] hyalurononglucosaminidase activity [GO:0004415] 0.9695 -3.0929 AFMKETIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8433 0 9.0091 0 0 0 Q2M3V2 SWAHA_HUMAN Ankyrin repeat domain-containing protein SOWAHA (Ankyrin repeat domain-containing protein 43) (Protein sosondowah homolog A) SOWAHA ANKRD43 Homo sapiens (Human) 0.80881 0.23129 GPPQQKPCMLPVR 0 0 0 10.1866 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q2M3W8 ZN181_HUMAN Zinc finger protein 181 (HHZ181) ZNF181 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.81106 0.22463 LSKGMIPDWESR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.5644 0 0 0 0 0 9.21026 0 0 8.87437 0 0 0 0 Q2M5E4 RGS21_HUMAN Regulator of G-protein signaling 21 (RGS21) RGS21 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; sensory perception of bitter taste [GO:0050913]; sensory perception of sweet taste [GO:0050916]; sensory perception of umami taste [GO:0050917]; transmission of nerve impulse [GO:0019226] plasma membrane [GO:0005886] GTPase activity [GO:0003924] 0.8006 0.23912 LIYCLMAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.259 Q2MJR0 SPRE3_HUMAN "Sprouty-related, EVH1 domain-containing protein 3 (Spred-3)" SPRED3 EVE-3 Homo sapiens (Human) negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of lens fiber cell differentiation [GO:1902747]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512] plasma membrane [GO:0005886] protein kinase binding [GO:0019901] 0.88098 0.01366 ADGRGGR 0 0 0 0 0 0 0 10.6897 0 0 0 0 0 8.37595 0 0 0 0 0 0 8.48398 0 0 0 0 8.61091 0 Q2MKA7 RSPO1_HUMAN R-spondin-1 (Roof plate-specific spondin-1) (hRspo1) RSPO1 Homo sapiens (Human) positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of receptor internalization [GO:0002090]; Wnt signaling pathway [GO:0016055] extracellular region [GO:0005576]; nucleus [GO:0005634] G protein-coupled receptor binding [GO:0001664]; heparin binding [GO:0008201]; signaling receptor binding [GO:0005102] 0.67397 0.39371 EAGAGSR 0 0 0 0 0 0 0 0 0 9.48055 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q2NKX8 ERC6L_HUMAN DNA excision repair protein ERCC-6-like (EC 3.6.4.12) (ATP-dependent helicase ERCC6-like) (PLK1-interacting checkpoint helicase) (Tumor antigen BJ-HCC-15) ERCC6L PICH Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301] cytosol [GO:0005829]; kinetochore [GO:0000776]; membrane [GO:0016020] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent chromatin remodeler activity [GO:0140658]; DNA binding [GO:0003677]; DNA translocase activity [GO:0015616]; helicase activity [GO:0004386] 0.96857 -3.8544 DIFPNEK 9.78013 12.389 12.1429 9.52282 9.47515 0 8.56769 11.7814 11.8207 10.2432 11.4203 9.57262 0 0 0 0 0 9.74621 10.2717 0 0 0 9.4765 0 0 0 0 Q2NKX9 CB068_HUMAN UPF0561 protein C2orf68 C2orf68 Homo sapiens (Human) 0.36722 0.73892 LDMNHGFVHHIRR 0 0 0 0 0 8.88926 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q2NL67 PARP6_HUMAN Protein mono-ADP-ribosyltransferase PARP6 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 17) (ARTD17) (Poly [ADP-ribose] polymerase 6) (PARP-6) PARP6 Homo sapiens (Human) endoplasmic reticulum unfolded protein response [GO:0030968]; positive regulation of dendrite morphogenesis [GO:0050775]; protein auto-ADP-ribosylation [GO:0070213] endoplasmic reticulum tubular network [GO:0071782]; nuclear envelope [GO:0005635] kinase binding [GO:0019900]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+- protein-aspartate ADP-ribosyltransferase activity [GO:0140806]; NAD+- protein-cysteine ADP-ribosyltransferase activity [GO:0140803]; nucleotidyltransferase activity [GO:0016779]; protein serine/threonine kinase activator activity [GO:0043539] 0.5599 0.51953 AALESPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1029 Q2NL68 PRSR3_HUMAN Proline and serine-rich protein 3 PROSER3 C19orf55 Homo sapiens (Human) centrosome [GO:0005813]; cytoplasm [GO:0005737] 0.96539 -2.291 AELSRQKR 0 0 0 10.0897 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q2NL82 TSR1_HUMAN Pre-rRNA-processing protein TSR1 homolog TSR1 KIAA1401 Homo sapiens (Human) "endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000479]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]" "cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; preribosome, small subunit precursor [GO:0030688]" GTP binding [GO:0005525]; GTPase activity [GO:0003924]; RNA binding [GO:0003723]; U3 snoRNA binding [GO:0034511] 0.9696 -4.9184 EAVLAEK 11.6241 0 8.92914 0 0 0 0 11.7417 0 11.208 9.03251 11.485 11.1755 0 0 0 0 10.6375 8.74012 0 9.5724 0 0 8.92351 0 0 0 Q2PPJ7 RGPA2_HUMAN Ral GTPase-activating protein subunit alpha-2 (250 kDa substrate of Akt) (AS250) (p220) RALGAPA2 C20orf74 KIAA1272 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886] GTPase activator activity [GO:0005096]; protein heterodimerization activity [GO:0046982] 0.87096 0.055153 ELKNLDSRQCR 0 0 0 0 0 0 0 10.9342 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4285 0 0 0 Q2PZI1 D19L1_HUMAN Probable C-mannosyltransferase DPY19L1 (EC 2.4.1.-) (Dpy-19-like protein 1) (Protein dpy-19 homolog 1) DPY19L1 GA0500 KIAA0877 Homo sapiens (Human) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan [GO:0018406] membrane [GO:0016020]; nuclear inner membrane [GO:0005637] mannosyltransferase activity [GO:0000030] 0.92114 -1.0915 ETPLRYTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0232 0 0 0 0 0 0 0 0 0 0 0 0 Q2QD12 RPEL1_HUMAN Ribulose-phosphate 3-epimerase-like protein 1 (EC 5.1.3.1) (Ribulose-5-phosphate-3-epimerase-like protein 1) RPEL1 Homo sapiens (Human) "carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]" cytosol [GO:0005829] D-ribulose-phosphate 3-epimerase activity [GO:0004750]; metal ion binding [GO:0046872] 0.94927 -1.3788 NICSEAAQKRSLDR 0 0 11.0451 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q2QGD7 ZXDC_HUMAN Zinc finger protein ZXDC (ZXD-like zinc finger protein) ZXDC ZXDL Homo sapiens (Human) positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] C2H2 zinc finger domain binding [GO:0070742]; LRR domain binding [GO:0030275]; metal ion binding [GO:0046872]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712] 0.88509 -0.33334 HSMKAHMVR 0 0 0 0 0 0 0 0 9.34361 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q2T9J0 TYSD1_HUMAN "Peroxisomal leader peptide-processing protease (EC 3.4.21.-) (Trypsin domain-containing protein 1) [Cleaved into: Peroxisomal leader peptide-processing protease, 15 kDa form; Peroxisomal leader peptide-processing protease, 45 kDa form]" TYSND1 Homo sapiens (Human) protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of fatty acid beta-oxidation [GO:0031998] cytosol [GO:0005829]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777] identical protein binding [GO:0042802]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252] 0.93218 -1.2601 LFGDEAAEQWRFSSAAR 0 0 0 0 0 0 0 0 0 0 9.65478 0 0 0 0 0 0 11.0211 0 0 0 0 0 0 0 0 0 Q2T9L4 INSY1_HUMAN Inhibitory synaptic factor 1 (InSyn1) INSYN1 C15orf59 Homo sapiens (Human) inhibitory postsynaptic potential [GO:0060080] postsynaptic density [GO:0014069] 0.89838 -0.64951 MNIRGAPDLGQPSDDPSSGGER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2508 0 0 0 0 0 0 0 0 0 0 Q2TAA5 ALG11_HUMAN "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (EC 2.4.1.131) (Asparagine-linked glycosylation protein 11 homolog) (Glycolipid 2-alpha-mannosyltransferase)" ALG11 GT8 Homo sapiens (Human) oligosaccharide-lipid intermediate biosynthetic process [GO:0006490]; protein N-linked glycosylation [GO:0006487] endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] "alpha-1,2-mannosyltransferase activity [GO:0000026]; GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity [GO:0004377]" 0.96884 -3.3761 VLWCALR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.044 0 0 0 0 0 0 0 0 0 0 0 0 0 Q2TAA8 TXIP1_HUMAN Translin-associated factor X-interacting protein 1 (Trax-interacting protein 1) TSNAXIP1 TXI1 Homo sapiens (Human) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; perinuclear region of cytoplasm [GO:0048471] 0.60553 0.43688 DLQEQLDTLR 0 0 0 0 0 0 0 12.1548 0 10.2024 0 0 0 0 12.3845 0 0 0 0 0 0 9.7354 0 0 0 10.6278 0 Q2TAC2 CCD57_HUMAN Coiled-coil domain-containing protein 57 CCDC57 Homo sapiens (Human) centriole replication [GO:0007099]; cilium assembly [GO:0060271]; G2/M transition of mitotic cell cycle [GO:0000086]; microtubule nucleation [GO:0007020]; positive regulation of mitotic cell cycle [GO:0045931] centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; spindle microtubule [GO:0005876] 0.40965 0.69312 DAAIDQLR 0 0 0 0 0 0 0 0 0 0 0 0 11.2614 0 0 0 0 0 0 9.70482 0 0 0 0 0 0 0 Q2TAC6 KIF19_HUMAN Kinesin-like protein KIF19 KIF19 Homo sapiens (Human) axonemal microtubule depolymerization [GO:0060404]; microtubule-based movement [GO:0007018]; plus-end specific microtubule depolymerization [GO:0070462] axoneme [GO:0005930]; cilium [GO:0005929]; kinesin complex [GO:0005871]; microtubule [GO:0005874] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; microtubule binding [GO:0008017]; plus-end-directed microtubule motor activity [GO:0008574] 0.80146 0.23941 SLCDEIIQGQR 0 0 0 0 0 0 0 0 0 0 0 11.011 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q2TAL8 QRIC1_HUMAN Transcriptional regulator QRICH1 (Glutamine-rich protein 1) QRICH1 Homo sapiens (Human) endoplasmic reticulum unfolded protein response [GO:0030968]; integrated stress response signaling [GO:0140467]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-templated transcription [GO:0045893]; response to endoplasmic reticulum stress [GO:0034976] cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] DNA binding [GO:0003677] 0.92726 -1.1934 NAELEKDAQNR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0311 0 0 0 0 0 0 0 10.0232 9.65091 0 11.3908 0 0 Q2TAY7 SMU1_HUMAN "WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog) [Cleaved into: WD40 repeat-containing protein SMU1, N-terminally processed]" SMU1 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]" cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; precatalytic spliceosome [GO:0071011]; U2-type precatalytic spliceosome [GO:0071005] 0.54428 0.57644 IQSGQCLRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.00846 0 0 0 0 0 0 0 0 Q2TAZ0 ATG2A_HUMAN Autophagy-related protein 2 homolog A ATG2A KIAA0404 Homo sapiens (Human) autophagosome assembly [GO:0000045]; autophagy of mitochondrion [GO:0000422]; late nucleophagy [GO:0044805]; piecemeal microautophagy of the nucleus [GO:0034727]; positive regulation of autophagosome assembly [GO:2000786]; reticulophagy [GO:0061709] endoplasmic reticulum membrane [GO:0005789]; lipid droplet [GO:0005811]; organelle membrane contact site [GO:0044232]; phagophore assembly site [GO:0000407]; phagophore assembly site membrane [GO:0034045] lipid transfer activity [GO:0120013]; phosphatidylinositol-3-phosphate binding [GO:0032266] 0.95492 -1.5632 DGPFGSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.97985 0 0 0 0 0 0 0 0 Q2TB10 ZN800_HUMAN Zinc finger protein 800 ZNF800 PP902 Homo sapiens (Human) acinar cell differentiation [GO:0090425]; endocrine pancreas development [GO:0031018] nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.87071 0.050067 STSPSAAGGQQK 0 0 0 0 0 0 8.64526 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q2TB90 HKDC1_HUMAN Hexokinase HKDC1 (EC 2.7.1.1) (Hexokinase domain-containing protein 1) HKDC1 Homo sapiens (Human) carbohydrate phosphorylation [GO:0046835]; glucose 6-phosphate metabolic process [GO:0051156]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; intracellular glucose homeostasis [GO:0001678] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; photoreceptor inner segment [GO:0001917] ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536] 0.96983 -5.9571 AELEYGLK 18.169 18.392 17.9736 15.2057 15.185 15.2892 18.2159 18.1819 18.1902 18.8701 18.7519 18.6811 14.8874 14.8251 14.9252 15.9976 16.466 16.2938 12.1857 12.0771 11.0383 0 11.2279 12.0146 11.8448 0 10.1311 Q2TBA0 KLH40_HUMAN Kelch-like protein 40 (Kelch repeat and BTB domain-containing protein 5) (Sarcosynapsin) KLHL40 KBTBD5 SRYP Homo sapiens (Human) negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; skeletal muscle fiber development [GO:0048741]; skeletal muscle fiber differentiation [GO:0098528] A band [GO:0031672]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; I band [GO:0031674] 0.89878 -0.64755 CLDSVMCYDR 0 10.1491 10.0027 0 0 0 0 0 0 0 0 0 0 0 0 0 8.47013 0 0 0 0 0 0 9.72289 0 0 0 Q2TBE0 C19L2_HUMAN CWF19-like protein 2 CWF19L2 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]" nucleoplasm [GO:0005654]; post-mRNA release spliceosomal complex [GO:0071014] 0.9692 -3.0666 AIAEHRSLAAQMEK 0 0 0 0 0 0 0 8.67599 0 0 9.62857 9.49229 0 0 0 9.90444 0 0 0 0 0 0 0 0 0 0 0 Q2TBF2 WSCD2_HUMAN Sialate:O-sulfotransferase 2 (WSC domain-containing protein 2) WSCD2 KIAA0789 Homo sapiens (Human) Golgi membrane [GO:0000139] sulfotransferase activity [GO:0008146] 0.96789 -2.8804 AKLGDYGGAWSR 9.90284 12.9883 0 9.47257 0 0 0 0 0 0 11.8603 0 0 0 0 0 0 0 0 0 0 0 10.0775 0 0 0 0 Q2UY09 COSA1_HUMAN Collagen alpha-1(XXVIII) chain COL28A1 COL28 Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198]; negative regulation of peptidase activity [GO:0010466] basement membrane [GO:0005604]; collagen type V trimer [GO:0005588]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] extracellular matrix structural constituent [GO:0005201]; serine-type endopeptidase inhibitor activity [GO:0004867] 0.96923 -6.0924 GEIGEPGSPGKQGLQGPK 0 0 0 0 0 0 0 0 0 9.27235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q2V2M9 FHOD3_HUMAN FH1/FH2 domain-containing protein 3 (Formactin-2) (Formin homolog overexpressed in spleen 2) (hFHOS2) FHOD3 FHOS2 KIAA1695 Homo sapiens (Human) cardiac myofibril assembly [GO:0055003]; cortical actin cytoskeleton organization [GO:0030866]; negative regulation of actin filament polymerization [GO:0030837]; sarcomere organization [GO:0045214] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; Z disc [GO:0030018] actin filament binding [GO:0051015] 0.96982 -5.0022 CREFLWSK 0 0 0 0 0 0 0 0 0 9.74312 0 0 0 0 0 0 0 0 0 0 9.637 0 0 0 0 0 0 Q2VIQ3 KIF4B_HUMAN Chromosome-associated kinesin KIF4B (Chromokinesin-B) KIF4B Homo sapiens (Human) microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle midzone assembly [GO:0051256]; mitotic spindle organization [GO:0007052]; spindle elongation [GO:0051231] cytosol [GO:0005829]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654] ATP binding [GO:0005524]; DNA binding [GO:0003677]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777] 0.96931 -4.1083 ELQTAKKNVNQAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.69897 0 0 0 0 0 0 0 0 0 0 0 0 Q2VIR3 IF2GL_HUMAN Eukaryotic translation initiation factor 2 subunit 3B (EC 3.6.5.3) (Eukaryotic translation initiation factor 2 subunit gamma A) (eIF-2-gamma A) (eIF-2gA) EIF2S3B Homo sapiens (Human) formation of translation preinitiation complex [GO:0001731] eukaryotic translation initiation factor 2 complex [GO:0005850] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation initiation factor activity [GO:0003743]; tRNA binding [GO:0000049] 0.84544 0.15382 GVTIKPTVDDD 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.75129 8.77195 0 0 0 0 Q2VPB7 AP5B1_HUMAN AP-5 complex subunit beta-1 (Adaptor-related protein complex 5 beta subunit) (Beta5) AP5B1 PP1030 Homo sapiens (Human) endosomal transport [GO:0016197]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] AP-5 adaptor complex [GO:0044599]; AP-type membrane coat adaptor complex [GO:0030119]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765] 0.95885 -1.7742 EHSPEEARELR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0336 Q2VPJ9 LR75B_HUMAN Leucine-rich repeat-containing protein 75B (Leucine-rich repeat-containing protein FAM211B) LRRC75B C22orf36 FAM211B Homo sapiens (Human) 0.96431 -2.2679 EIQSTLRER 0 0 0 0 0 0 0 0 0 0 0 0 10.7021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q2VWP7 PRTG_HUMAN Protogenin (Protein Shen-Dan) PRTG Homo sapiens (Human) cell-cell adhesion [GO:0098609]; negative regulation of neurogenesis [GO:0050768] extracellular space [GO:0005615]; plasma membrane [GO:0005886] identical protein binding [GO:0042802]; signaling receptor activity [GO:0038023] 0.84765 0.16911 DLLYTLSGLDPR 10.6647 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q2WGJ6 KLH38_HUMAN Kelch-like protein 38 KLHL38 C8orfK36 Homo sapiens (Human) 0.9244 -1.0092 ILAYDPQSNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.62092 0 0 10.6611 Q2WGJ9 FR1L6_HUMAN Fer-1-like protein 6 FER1L6 C8orfK23 Homo sapiens (Human) positive regulation of gene expression [GO:0010628]; response to bacterium [GO:0009617] membrane [GO:0016020] metal ion binding [GO:0046872] 0.87799 -0.00469 AFVGDSK 0 0 0 0 0 9.36543 0 8.38336 0 0 0 0 0 0 0 9.82804 0 0 0 0 0 0 0 9.89251 0 0 0 Q2WGN9 GAB4_HUMAN GRB2-associated-binding protein 4 (GRB2-associated binder 2-like) (GAB2-like) (GRB2-associated binder 4) (GRB2-associated-binding protein 2-like) (Growth factor receptor bound protein 2-associated protein 4) GAB4 Homo sapiens (Human) signal transduction [GO:0007165] cytoplasm [GO:0005737] transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068] 0.89657 -0.54442 LRLFAWRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3006 0 Q2Y0W8 S4A8_HUMAN Electroneutral sodium bicarbonate exchanger 1 (Electroneutral Na(+)-driven Cl-HCO3 exchanger) (Solute carrier family 4 member 8) (k-NBC3) SLC4A8 KIAA0739 NBC NBC3 NDCBE1 Homo sapiens (Human) bicarbonate transport [GO:0015701]; chloride transmembrane transport [GO:1902476]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic vesicle exocytosis [GO:2000302]; regulation of intracellular pH [GO:0051453]; regulation of membrane potential [GO:0042391]; sodium ion transmembrane transport [GO:0035725]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104] apical plasma membrane [GO:0016324]; asymmetric synapse [GO:0032279]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; dendrite [GO:0030425]; glial cell projection [GO:0097386]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber [GO:0097457]; membrane [GO:0016020]; neuron projection [GO:0043005]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; presynaptic membrane [GO:0042734]; symmetric synapse [GO:0032280]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195] "bicarbonate transmembrane transporter activity [GO:0015106]; chloride transmembrane transporter activity [GO:0015108]; identical protein binding [GO:0042802]; sodium ion transmembrane transporter activity [GO:0015081]; sodium,bicarbonate:chloride antiporter activity [GO:0140892]; sodium:bicarbonate symporter activity [GO:0008510]; solute:inorganic anion antiporter activity [GO:0005452]; zinc ion binding [GO:0008270]" 0.95502 -1.52 ALSMNSGNAKEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4297 0 Q2YD98 UVSSA_HUMAN UV-stimulated scaffold protein A UVSSA KIAA1530 Homo sapiens (Human) protein ubiquitination [GO:0016567]; response to UV [GO:0009411]; transcription-coupled nucleotide-excision repair [GO:0006283] chromosome [GO:0005694]; nucleoplasm [GO:0005654] RNA polymerase II complex binding [GO:0000993] 0.8846 -0.13012 RQLQKQERPEWQDPELMR 0 0 0 0 0 0 9.95774 9.92028 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q30154 DRB5_HUMAN "HLA class II histocompatibility antigen, DR beta 5 chain (DR beta-5) (DR2-beta-2) (Dw2) (MHC class II antigen DRB5)" HLA-DRB5 Homo sapiens (Human) adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; positive regulation of T cell activation [GO:0050870] clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; late endosome membrane [GO:0031902]; lumenal side of endoplasmic reticulum membrane [GO:0098553]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658] MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605] 0.96257 -2.5491 DFLEDRR 0 0 0 0 0 0 0 10.3806 0 10.5214 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q30201 HFE_HUMAN Hereditary hemochromatosis protein (HLA-H) HFE HLAH Homo sapiens (Human) "antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent [GO:0002486]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; BMP signaling pathway [GO:0030509]; cellular response to iron ion [GO:0071281]; hormone biosynthetic process [GO:0042446]; intracellular iron ion homeostasis [GO:0006879]; iron ion transmembrane transport [GO:0034755]; multicellular organismal-level iron ion homeostasis [GO:0060586]; negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:1904283]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of receptor binding [GO:1900121]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of T cell cytokine production [GO:0002725]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of gene expression [GO:0010628]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein-containing complex assembly [GO:0065003]; regulation of iron ion transport [GO:0034756]; regulation of protein localization to cell surface [GO:2000008]; response to iron ion [GO:0010039]; response to iron ion starvation [GO:1990641]" apical part of cell [GO:0045177]; basal part of cell [GO:0045178]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; HFE-transferrin receptor complex [GO:1990712]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037] beta-2-microglobulin binding [GO:0030881]; co-receptor binding [GO:0039706]; signaling receptor binding [GO:0005102]; transferrin receptor binding [GO:1990459] 0.96326 -2.2407 CRALNYYPQNITMK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3387 0 0 0 11.8751 0 0 0 0 0 0 0 0 0 Q32M45 ANO4_HUMAN Anoctamin-4 (Transmembrane protein 16D) ANO4 TMEM16D Homo sapiens (Human) calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; calcium activated phosphatidylserine scrambling [GO:0061589]; chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; establishment of localization in cell [GO:0051649]; monoatomic ion transmembrane transport [GO:0034220] plasma membrane [GO:0005886] intracellular calcium activated chloride channel activity [GO:0005229]; phospholipid scramblase activity [GO:0017128]; protein dimerization activity [GO:0046983] 0.89773 -0.58257 MNPISGKPEPYQAFTDK 0 11.7146 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q32M84 BTBDG_HUMAN BTB/POZ domain-containing protein 16 BTBD16 C10orf87 Homo sapiens (Human) 0.95448 -1.5088 ELEELLR 0 0 0 0 0 9.49133 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q32M88 PGGHG_HUMAN Protein-glucosylgalactosylhydroxylysine glucosidase (EC 3.2.1.107) (Acid trehalase-like protein 1) PGGHG ATHL1 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975] cytosol [GO:0005829] protein-glucosylgalactosylhydroxylysine glucosidase activity [GO:0047402] 0.86331 0.080092 LPGSSSSEFPGRTFSDVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1513 0 0 0 0 0 0 0 0 0 0 0 Q32MH5 ATOSA_HUMAN Atos homolog protein A ATOSA FAM214A KIAA1370 Homo sapiens (Human) nucleus [GO:0005634] 0.96961 -4.0123 SVNKENIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2833 0 0 0 0 0 0 0 0 0 0 0 Q32MK0 MYLK3_HUMAN Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) (Cardiac-MLCK) MYLK3 MLCK Homo sapiens (Human) cardiac myofibril assembly [GO:0055003]; cellular response to interleukin-1 [GO:0071347]; positive regulation of sarcomere organization [GO:0060298]; protein phosphorylation [GO:0006468]; regulation of vascular permeability involved in acute inflammatory response [GO:0002528]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829] ATP binding [GO:0005524]; calmodulin-dependent protein kinase activity [GO:0004683]; myosin light chain kinase activity [GO:0004687] 0.91615 -0.8405 HFYVVTAANR 0 0 0 0 0 0 0 0 0 9.53171 0 0 0 0 0 8.70224 9.47669 0 0 0 0 0 0 0 0 0 0 Q32MZ4 LRRF1_HUMAN Leucine-rich repeat flightless-interacting protein 1 (LRR FLII-interacting protein 1) (GC-binding factor 2) (TAR RNA-interacting protein) LRRFIP1 GCF2 TRIP Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886] "cadherin binding [GO:0045296]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded RNA binding [GO:0003725]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.93903 -1.3214 EMKDSLAEVEEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7361 0 0 Q32NB8 PGPS1_HUMAN "CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial (EC 2.7.8.5) (Phosphatidylglycerophosphate synthase 1) (PGP synthase 1)" PGS1 Homo sapiens (Human) cardiolipin biosynthetic process [GO:0032049]; diacylglycerol metabolic process [GO:0046339]; phosphatidylglycerol biosynthetic process [GO:0006655] endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity [GO:0008444] 0.95823 -1.6711 GWTFHAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.36691 0 0 0 0 0 0 Q32NC0 CR021_HUMAN UPF0711 protein C18orf21 (HBV X-transactivated gene 13 protein) (HBV XAg-transactivated protein 13) C18orf21 XTP13 PNAS-124 PNAS-131 Homo sapiens (Human) 0.96107 -2.0029 LSLKTPER 0 0 0 0 0 0 0 0 0 0 8.5766 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q32P28 P3H1_HUMAN Prolyl 3-hydroxylase 1 (EC 1.14.11.7) (Growth suppressor 1) (Leucine- and proline-enriched proteoglycan 1) (Leprecan-1) P3H1 GROS1 LEPRE1 PSEC0109 Homo sapiens (Human) bone development [GO:0060348]; chaperone-mediated protein folding [GO:0061077]; collagen metabolic process [GO:0032963]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of post-translational protein modification [GO:1901874]; positive regulation of neuron projection development [GO:0010976]; protein folding [GO:0006457]; protein hydroxylation [GO:0018126]; protein stabilization [GO:0050821]; regulation of protein secretion [GO:0050708] cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] iron ion binding [GO:0005506]; L-ascorbic acid binding [GO:0031418]; procollagen-proline 3-dioxygenase activity [GO:0019797] 0.95621 -1.5502 DLETQPHMQEFRLGVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.34926 0 Q32P44 EMAL3_HUMAN Echinoderm microtubule-associated protein-like 3 (EMAP-3) EML3 Homo sapiens (Human) cell division [GO:0051301]; microtubule cytoskeleton organization [GO:0000226]; mitotic metaphase plate congression [GO:0007080]; regulation of mitotic spindle assembly [GO:1901673] cytoplasm [GO:0005737]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; mitotic spindle microtubule [GO:1990498]; nucleus [GO:0005634]; spindle [GO:0005819]; spindle microtubule [GO:0005876] microtubule binding [GO:0008017]; protein self-association [GO:0043621] 0.77133 0.26796 GTQTETEVELK 9.29133 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q330K2 NDUF6_HUMAN "NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 (Putative phytoene synthase)" NDUFAF6 C8orf38 Homo sapiens (Human) biosynthetic process [GO:0009058]; mitochondrial respiratory chain complex I assembly [GO:0032981] cytoplasm [GO:0005737]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; nucleus [GO:0005634] 0.91803 -0.87027 IVDEREKNLDDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.90189 0 0 Q38SD2 LRRK1_HUMAN Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1) LRRK1 KIAA1790 Homo sapiens (Human) bone resorption [GO:0045453]; intracellular signal transduction [GO:0035556]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; osteoclast development [GO:0036035]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; protein phosphorylation [GO:0006468] cytosol [GO:0005829]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.92399 -1.0154 GEEVVWCLDDK 0 0 0 0 0 0 0 0 0 15.5185 10.0275 0 0 0 0 0 0 10.9743 0 0 0 0 0 0 0 0 11.4596 Q3B7S5 SMI21_HUMAN Small integral membrane protein 21 SMIM21 C18orf62 Homo sapiens (Human) membrane [GO:0016020] 0.9144 -0.78396 IQGVSEDWKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8271 0 0 0 0 0 0 0 0 Q3B7T1 EDRF1_HUMAN Erythroid differentiation-related factor 1 EDRF1 C10orf137 Homo sapiens (Human) positive regulation of DNA-templated transcription [GO:0045893] nucleus [GO:0005634] 0.89886 -0.6037 EAGAEGPPAGAAAR 11.1786 11.5203 11.2207 0 0 0 10.4574 10.9504 11.0048 10.8868 0 10.8858 0 9.07743 9.11769 10.6182 0 0 10.1557 0 0 0 0 0 0 0 12.3894 Q3B820 F161A_HUMAN Protein FAM161A FAM161A Homo sapiens (Human) cilium assembly [GO:0060271]; cilium organization [GO:0044782]; positive regulation of protein acetylation [GO:1901985]; response to stimulus [GO:0050896]; visual perception [GO:0007601] astral microtubule [GO:0000235]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; mitotic spindle [GO:0072686]; mitotic spindle pole [GO:0097431]; photoreceptor connecting cilium [GO:0032391]; photoreceptor inner segment [GO:0001917]; spindle microtubule [GO:0005876] identical protein binding [GO:0042802]; microtubule binding [GO:0008017] 0.88423 -0.16182 CPTPDFEDLPERYQKHLSEHK 0 0 0 8.87391 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q3BBV0 NBPF1_HUMAN Neuroblastoma breakpoint family member 1 NBPF1 KIAA1693 Homo sapiens (Human) cytoplasm [GO:0005737] 0.58869 0.46431 VGWALDMDEIEK 0 0 0 0 0 0 9.3612 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6547 Q3BBV2 NBPF8_HUMAN Putative neuroblastoma breakpoint family member 8 NBPF8 NBPF8P Homo sapiens (Human) cytoplasm [GO:0005737] 0.85732 0.10009 LPGQPTEEIQQYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.40703 0 0 0 0 0 0 0 0 Q3C1V9 YK041_HUMAN Putative uncharacterized protein ENSP00000334305 Homo sapiens (Human) intracellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826] external side of plasma membrane [GO:0009897] 0.96387 -2.3941 APAVGCR 0 0 0 0 8.16088 0 0 0 0 8.81372 0 0 0 9.02486 0 0 0 0 0 0 0 9.11121 0 8.95423 0 0 0 Q3KNS1 PTHD3_HUMAN Patched domain-containing protein 3 (Patched-related protein) PTCHD3 PTR Homo sapiens (Human) endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886]; sperm midpiece [GO:0097225] 0.9641 -2.2612 DVRQKLENCTK 8.93643 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.62244 0 0 0 Q3KNS6 ZN829_HUMAN Zinc finger protein 829 ZNF829 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.87 0.057951 GLCSDLESMCETK 0 0 0 0 0 11.0899 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q3KNV8 PCGF3_HUMAN Polycomb group RING finger protein 3 (RING finger protein 3A) PCGF3 RNF3 RNF3A Homo sapiens (Human) histone H2A-K119 monoubiquitination [GO:0036353]; inactivation of X chromosome by genomic imprinting [GO:0060819]; regulation of transcription by RNA polymerase II [GO:0006357] nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PcG protein complex [GO:0031519]; PRC1 complex [GO:0035102]; X chromosome [GO:0000805] metal ion binding [GO:0046872] 0.95102 -1.4342 APLLLHYRPK 0 0 0 0 10.0283 10.0787 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.13896 9.22149 0 0 0 0 Q3KP31 ZN791_HUMAN Zinc finger protein 791 ZNF791 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.96975 -4.1278 AFRCSTSIQIHER 0 0 0 0 0 0 0 0 9.81372 9.67673 0 10.7629 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0729 Q3KP66 INAVA_HUMAN Innate immunity activator protein INAVA C1orf106 Homo sapiens (Human) adherens junction maintenance [GO:0034334]; innate immune response [GO:0045087]; intestinal epithelial structure maintenance [GO:0060729]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; reactive oxygen species biosynthetic process [GO:1903409]; response to muramyl dipeptide [GO:0032495]; response to peptidoglycan [GO:0032494] cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.88472 -0.14653 EARGEGRWPGQTGPEAAR 0 0 0 0 0 0 9.67331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q3KQU3 MA7D1_HUMAN MAP7 domain-containing protein 1 (Arginine/proline-rich coiled-coil domain-containing protein 1) (Proline/arginine-rich coiled-coil domain-containing protein 1) MAP7D1 KIAA1187 PARCC1 RPRC1 PP2464 Homo sapiens (Human) microtubule cytoskeleton organization [GO:0000226] cytoplasm [GO:0005737]; microtubule cytoskeleton [GO:0015630]; spindle [GO:0005819] 0.96919 -4.7658 EEAERQR 0 0 0 0 8.94254 0 0 0 0 10.4329 10.4216 10.481 0 0 0 0 0 0 9.38321 0 0 0 9.40911 9.27263 0 0 0 Q3KQV3 ZN792_HUMAN Zinc finger protein 792 ZNF792 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96776 -2.8181 FFSRSSNLIQHK 0 0 0 0 0 8.69418 0 0 0 0 0 0 0 0 0 0 0 0 11.522 0 0 0 0 0 0 0 0 Q3KRA6 CB076_HUMAN UPF0538 protein C2orf76 C2orf76 Homo sapiens (Human) 0.8843 -0.13731 TNLPPPFRNYK 0 0 0 0 0 9.08124 0 0 0 0 0 0 10.3464 0 0 0 0 11.1293 0 0 0 0 0 0 0 0 0 Q3L8U1 CHD9_HUMAN Chromodomain-helicase-DNA-binding protein 9 (CHD-9) (EC 3.6.4.12) (ATP-dependent helicase CHD9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin-remodeling factor CHROM1) (Kismet homolog 2) (PPAR-alpha-interacting complex protein 320 kDa) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) CHD9 KIAA0308 KISH2 PRIC320 AD-013 x0008 Homo sapiens (Human) cytosol [GO:0005829]; nucleoplasm [GO:0005654] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent chromatin remodeler activity [GO:0140658]; DNA binding [GO:0003677]; helicase activity [GO:0004386] 0.96972 -5.2717 ALLAYCLVHYR 0 0 0 0 0 0 9.17173 11.0928 0 11.1812 0 10.6944 0 0 0 9.7912 10.8163 0 0 0 0 0 0 0 0 0 0 Q3LI62 KR204_HUMAN Putative keratin-associated protein 20-4 KRTAP20-4 KAP20.4 Homo sapiens (Human) intermediate filament [GO:0005882] 0.9145 -0.77983 CRHGCHSSYSAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.16887 0 0 0 0 0 Q3LI77 KR134_HUMAN Keratin-associated protein 13-4 KRTAP13-4 KAP13.4 Homo sapiens (Human) cytosol [GO:0005829]; intermediate filament [GO:0005882] 0.90692 -0.74146 CCYSLGNGSSGFRFLK 0 0 0 0 0 9.34678 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q3LIE5 ADPRM_HUMAN Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase (EC 3.6.1.13) (EC 3.6.1.16) (EC 3.6.1.53) (ADPRibase-Mn) (CDP-choline phosphohydrolase) ADPRM C17orf48 MDS006 Nbla03831 Homo sapiens (Human) cytosol [GO:0005829] "2',3'-cyclic-nucleotide 2'-phosphodiesterase activity [GO:0008663]; ADP-ribose diphosphatase activity [GO:0047631]; CDP-glycerol diphosphatase activity [GO:0047734]; manganese ion binding [GO:0030145]" 0.95526 -1.6315 IMNYKKER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.99237 0 0 0 0 0 0 0 0 0 11.1431 0 0 Q3MIN7 RGL3_HUMAN Ral guanine nucleotide dissociation stimulator-like 3 (RalGDS-like 3) RGL3 Homo sapiens (Human) positive regulation of GTPase activity [GO:0043547]; Ras protein signal transduction [GO:0007265] cytosol [GO:0005829]; plasma membrane [GO:0005886] guanyl-nucleotide exchange factor activity [GO:0005085] 0.73301 0.32946 IAQRCRELR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.99472 0 0 0 0 Q3MIP1 IPIL2_HUMAN "Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2" ITPRIPL2 Homo sapiens (Human) membrane [GO:0016020] 0.92196 -1.1236 GLDSAAATQWGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7094 0 0 0 0 0 0 0 0 Q3MIS6 ZN528_HUMAN Zinc finger protein 528 ZNF528 KIAA1827 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96259 -2.5064 LFSSNSNLSQHQR 0 0 0 0 11.4471 11.4873 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.85801 0 0 Q3MIT2 PUS10_HUMAN tRNA pseudouridine synthase Pus10 (Hup10) (EC 5.4.99.25) (Coiled-coil domain-containing protein 139) (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA pseudouridylate synthase) (tRNA-uridine isomerase) PUS10 CCDC139 DOBI Homo sapiens (Human) primary miRNA processing [GO:0031053]; tRNA pseudouridine synthesis [GO:0031119] cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nucleus [GO:0005634] metal ion binding [GO:0046872]; primary miRNA binding [GO:0070878]; pseudouridine synthase activity [GO:0009982]; tRNA pseudouridine synthase activity [GO:0106029] 0.96949 -4.7338 EAIGHMK 0 0 0 0 0 0 0 0 0 0 11.53 0 8.67324 8.72707 0 8.45586 0 10.4019 0 0 0 10.1165 0 9.99081 9.56881 0 0 Q3MIW9 MUCL3_HUMAN Mucin-like protein 3 (Diffuse panbronchiolitis critical region protein 1) MUCL3 C6orf37 DPCR1 PBLT Homo sapiens (Human) cytoplasm [GO:0005737]; plasma membrane [GO:0005886] 0.96247 -2.4987 ITAASKTTYK 0 0 0 0 0 0 0 0 0 0 9.59908 9.3794 0 0 0 0 10.5029 0 0 0 0 0 0 0 0 0 0 Q3MJ62 ZSC23_HUMAN Zinc finger and SCAN domain-containing protein 23 (Zinc finger protein 390) (Zinc finger protein 453) ZSCAN23 ZNF390 ZNF453 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.42812 0.6632 QNGNITQIPEYGDTCDREGRLEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.871 0 0 Q3SXM5 HSDL1_HUMAN Inactive hydroxysteroid dehydrogenase-like protein 1 (Short chain dehydrogenase/reductase family 12C member 3) HSDL1 SDR12C3 Homo sapiens (Human) intermediate filament cytoskeleton [GO:0045111]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739] 0.86798 0.071133 AAVDSFYLLYR 0 0 0 0 0 0 0 0 0 8.27952 0 0 0 0 0 0 0 9.82955 0 0 0 0 9.42696 0 0 0 0 Q3SXZ3 ZN718_HUMAN Zinc finger protein 718 ZNF718 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.95918 -1.8649 INQCLLTTQK 0 0 0 0 0 0 0 0 0 0 0 9.1058 0 0 0 0 0 0 0 9.93979 0 0 0 0 0 11.6165 10.2774 Q3SXZ7 TTLL9_HUMAN Probable tubulin polyglutamylase TTLL9 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 9) TTLL9 C20orf125 Homo sapiens (Human) flagellated sperm motility [GO:0030317]; microtubule cytoskeleton organization [GO:0000226]; protein polyglutamylation [GO:0018095] ciliary basal body [GO:0036064]; cilium [GO:0005929]; cytoplasm [GO:0005737]; microtubule [GO:0005874]; motile cilium [GO:0031514] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; tubulin binding [GO:0015631]; tubulin-glutamic acid ligase activity [GO:0070740] 0.96773 -2.9651 DIVDWRKDTR 0 0 0 0 0 0 0 0 9.35167 0 0 0 0 0 0 0 0 0 0 0 9.35905 0 9.63214 9.46646 0 0 0 Q3SY00 T10IP_HUMAN Testis-specific protein 10-interacting protein (Tsga10-interacting protein) TSGA10IP Homo sapiens (Human) cilium organization [GO:0044782] photoreceptor connecting cilium [GO:0032391] 0.88333 -0.26646 AAFQASKRNGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.76471 9.57945 0 0 0 0 0 0 9.95697 0 Q3SY52 ZIK1_HUMAN Zinc finger protein interacting with ribonucleoprotein K (Zinc finger protein 762) ZIK1 ZNF762 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96115 -2.5603 AGSSTQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.56381 8.57281 0 0 9.14705 0 0 0 Q3SY69 AL1L2_HUMAN Mitochondrial 10-formyltetrahydrofolate dehydrogenase (Mitochondrial 10-FTHFDH) (mtFDH) (EC 1.5.1.6) (Aldehyde dehydrogenase family 1 member L2) ALDH1L2 Homo sapiens (Human) 10-formyltetrahydrofolate catabolic process [GO:0009258]; biosynthetic process [GO:0009058]; fatty acid beta-oxidation [GO:0006635]; folic acid metabolic process [GO:0046655]; NADPH regeneration [GO:0006740]; one-carbon metabolic process [GO:0006730] extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] "aldehyde dehydrogenase (NAD+) activity [GO:0004029]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]" 0.89804 -0.58228 ANSTEYGLASGVFTR 0 0 0 0 0 10.0591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q3SY77 UD3A2_HUMAN UDP-glucuronosyltransferase 3A2 (UDPGT 3A2) (EC 2.4.1.17) UGT3A2 PSEC0073 UNQ842/PRO1780 Homo sapiens (Human) cellular response to genistein [GO:0071412] UDP-N-acetylglucosamine transferase complex [GO:0043541] glucuronosyltransferase activity [GO:0015020]; UDP-glycosyltransferase activity [GO:0008194] 0.80777 0.22718 LLGMAVWWLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.09893 Q3SY84 K2C71_HUMAN "Keratin, type II cytoskeletal 71 (Cytokeratin-71) (CK-71) (Keratin-71) (K71) (Type II inner root sheath-specific keratin-K6irs1) (Keratin 6 irs) (hK6irs) (hK6irs1) (Type-II keratin Kb34)" KRT71 K6IRS1 KB34 KRT6IRS1 Homo sapiens (Human) hair follicle morphogenesis [GO:0031069]; intermediate filament organization [GO:0045109]; keratinization [GO:0031424] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; keratin filament [GO:0045095] structural constituent of skin epidermis [GO:0030280] 0.87549 0.0009225 FASFIDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.9448 0 0 0 0 0 Q3SYA9 P12L1_HUMAN Putative POM121-like protein 1 POM121L1P POM121L1 Homo sapiens (Human) 0.93776 -1.2937 DPRVQENPGDQRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3439 Q3SYC2 MOGT2_HUMAN 2-acylglycerol O-acyltransferase 2 (EC 2.3.1.22) (Acyl-CoA:monoacylglycerol acyltransferase 2) (MGAT2) (hMGAT2) (Diacylglycerol O-acyltransferase candidate 5) (hDC5) (Diacylglycerol acyltransferase 2-like protein 5) (Monoacylglycerol O-acyltransferase 2) MOGAT2 DC5 DGAT2L5 Homo sapiens (Human) diacylglycerol biosynthetic process [GO:0006651]; glycerol metabolic process [GO:0006071]; intestinal absorption [GO:0050892]; monoacylglycerol biosynthetic process [GO:0006640]; triglyceride biosynthetic process [GO:0019432] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; perinuclear endoplasmic reticulum membrane [GO:1990578] 2-acylglycerol O-acyltransferase activity [GO:0003846]; acetyltransferase activity [GO:0016407]; diacylglycerol O-acyltransferase activity [GO:0004144] 0.16162 0.99769 VEFAPLFMPWER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3869 0 0 0 0 0 0 0 Q3SYG4 PTHB1_HUMAN Protein PTHB1 (Bardet-Biedl syndrome 9 protein) (Parathyroid hormone-responsive B1 gene protein) BBS9 PTHB1 Homo sapiens (Human) cilium assembly [GO:0060271]; fat cell differentiation [GO:0045444]; protein localization to cilium [GO:0061512]; protein transport [GO:0015031]; response to stimulus [GO:0050896]; visual perception [GO:0007601] BBSome [GO:0034464]; centriolar satellite [GO:0034451]; ciliary membrane [GO:0060170]; ciliary transition zone [GO:0035869]; cilium [GO:0005929]; cytosol [GO:0005829]; membrane [GO:0016020]; pericentriolar material [GO:0000242] 0.95313 -1.4973 DNGQIRFMK 0 0 0 0 0 0 0 0 0 9.34179 0 0 0 9.82822 0 0 0 0 0 0 0 0 0 9.06499 0 0 0 Q3T8J9 GON4L_HUMAN GON-4-like protein (GON-4 homolog) GON4L GON4 KIAA1606 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] transcription coregulator activity [GO:0003712] 0.96971 -5.0648 ASPRLQKER 0 0 0 0 0 0 0 0 0 0 10.5691 0 9.6783 8.6466 0 0 0 0 0 0 10.1197 0 0 0 0 8.9788 0 Q3T906 GNPTA_HUMAN N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (EC 2.7.8.17) (GlcNAc-1-phosphotransferase subunits alpha/beta) (Stealth protein GNPTAB) (UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta) [Cleaved into: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta] GNPTAB GNPTA KIAA1208 Homo sapiens (Human) carbohydrate phosphorylation [GO:0046835]; lysosome organization [GO:0007040]; N-glycan processing to lysosome [GO:0016256]; secretion of lysosomal enzymes [GO:0033299] Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complex [GO:0070622] calcium ion binding [GO:0005509]; UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity [GO:0003976] 0.96939 -3.3094 DAQTVKAVLR 0 0 0 0 0 0 8.62253 0 0 0 0 0 0 0 0 0 0 0 0 0 9.26576 0 8.68748 0 0 0 0 Q3V6T2 GRDN_HUMAN Girdin (Akt phosphorylation enhancer) (APE) (Coiled-coil domain-containing protein 88A) (G alpha-interacting vesicle-associated protein) (GIV) (Girders of actin filament) (Hook-related protein 1) (HkRP1) CCDC88A APE GRDN KIAA1212 Homo sapiens (Human) activation of protein kinase activity [GO:0032147]; activation of protein kinase B activity [GO:0032148]; cell migration [GO:0016477]; cytoplasmic microtubule organization [GO:0031122]; cytoskeleton-dependent intracellular transport [GO:0030705]; DNA replication [GO:0006260]; lamellipodium assembly [GO:0030032]; maintenance of protein location in plasma membrane [GO:0072660]; membrane organization [GO:0061024]; nervous system development [GO:0007399]; positive regulation of cilium assembly [GO:0045724]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of protein localization to cilium [GO:1903566]; positive regulation of stress fiber assembly [GO:0051496]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell population proliferation [GO:0042127]; regulation of DNA replication [GO:0006275]; regulation of neuron projection development [GO:0010975]; regulation of protein phosphorylation [GO:0001932]; small GTPase mediated signal transduction [GO:0007264]; TOR signaling [GO:0031929] centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; lamellipodium [GO:0030027]; membrane [GO:0016020]; plasma membrane [GO:0005886] actin binding [GO:0003779]; dynein light intermediate chain binding [GO:0051959]; epidermal growth factor receptor binding [GO:0005154]; G-protein alpha-subunit binding [GO:0001965]; GDP-dissociation inhibitor activity [GO:0005092]; guanyl-nucleotide exchange factor activity [GO:0005085]; insulin receptor binding [GO:0005158]; microtubule binding [GO:0008017]; phosphatidylinositol binding [GO:0035091]; protein homodimerization activity [GO:0042803]; protein kinase B binding [GO:0043422]; protein kinase C binding [GO:0005080]; SH2 domain binding [GO:0042169]; vascular endothelial growth factor receptor 2 binding [GO:0043184] 0.9692 -7.2103 DLFHVEQR 0 0 9.54695 0 0 0 11.7209 13.6131 0 9.39528 11.5995 10.2875 10.4656 0 0 0 0 10.4865 0 10.8967 9.9226 11.2215 9.89418 0 0 11.0657 0 Q3YBM2 T176B_HUMAN Transmembrane protein 176B (Protein LR8) TMEM176B LR8 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; dendritic cell differentiation [GO:0097028]; negative regulation of dendritic cell differentiation [GO:2001199] nuclear membrane [GO:0031965] 0.96162 -2.0771 AYMQMLRK 0 12.8455 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q3YBR2 TBRG1_HUMAN Transforming growth factor beta regulator 1 (Nuclear interactor of ARF and Mdm2) TBRG1 NIAM Homo sapiens (Human) cell cycle [GO:0007049]; DNA replication [GO:0006260]; negative regulation of cell population proliferation [GO:0008285]; protein localization to nucleoplasm [GO:1990173]; protein stabilization [GO:0050821]; regulation of cell cycle [GO:0051726] nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.96893 -3.8774 APLQSSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.3458 0 0 0 0 0 0 9.52918 0 0 0 9.24982 Q3ZCN5 OTOGL_HUMAN Otogelin-like protein OTOGL C12orf64 Homo sapiens (Human) L-arabinose metabolic process [GO:0046373] extracellular matrix [GO:0031012]; extracellular space [GO:0005615] alpha-L-arabinofuranosidase activity [GO:0046556] 0.51573 0.59995 ILFAIDGER 10.1231 11.2137 0 0 0 0 8.9672 10.0305 0 9.73611 10.0214 9.74732 0 0 9.91834 0 0 0 0 0 0 9.4495 0 9.69523 0 0 0 Q3ZCQ8 TIM50_HUMAN Mitochondrial import inner membrane translocase subunit TIM50 TIMM50 TIM50 PRO1512 Homo sapiens (Human) intracellular protein transport [GO:0006886]; mitochondrial membrane organization [GO:0007006]; protein dephosphorylation [GO:0006470]; protein import into mitochondrial matrix [GO:0030150]; release of cytochrome c from mitochondria [GO:0001836] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; TIM23 mitochondrial import inner membrane translocase complex [GO:0005744] interleukin-2 receptor binding [GO:0005134]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine phosphatase activity [GO:0004725]; ribonucleoprotein complex binding [GO:0043021]; RNA binding [GO:0003723] 0.92113 -1.1401 LEQEEQQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.68963 9.98854 0 0 0 0 0 0 0 0 0 0 Q3ZCT1 ZN260_HUMAN Zinc finger protein 260 (Zfp-260) ZNF260 ZFP260 Homo sapiens (Human) cytosol [GO:0005829]; nucleoplasm [GO:0005654] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.89188 -0.51085 HHTGEKPYECEK 0 0 10.2999 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q3ZCT8 KBTBC_HUMAN Kelch repeat and BTB domain-containing protein 12 (Kelch domain-containing protein 6) KBTBD12 KLHDC6 Homo sapiens (Human) 0.92199 -1.1359 NQYLITNCVDKYSVER 0 0 0 0 0 0 0 0 0 10.4144 0 0 0 0 0 0 0 0 0 0 0 0 10.0221 0 0 0 0 Q3ZCV2 LEXM_HUMAN Lymphocyte expansion molecule LEXM LEM C1orf177 Homo sapiens (Human) 0.95037 -1.4025 EQKLGPGSYNLK 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2524 11.34 0 0 0 0 0 0 0 8.67617 0 0 0 0 Q401N2 ZACN_HUMAN Zinc-activated ligand-gated ion channel (Ligand-gated ion channel zinc-activated 1) (Ligand-gated ion-channel receptor L2) ZACN L2 LGICZ LGICZ1 ZAC Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; monoatomic ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to zinc ion [GO:0010043]; signal transduction [GO:0007165] plasma membrane [GO:0005886]; synapse [GO:0045202] extracellular ligand-gated monoatomic ion channel activity [GO:0005230]; ligand-gated monoatomic ion channel activity [GO:0015276]; neurotransmitter receptor activity [GO:0030594]; transmembrane signaling receptor activity [GO:0004888]; zinc ion binding [GO:0008270] 0.83615 0.18924 EYVVYDLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9504 Q460N3 PAR15_HUMAN Protein mono-ADP-ribosyltransferase PARP15 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 7) (ARTD7) (B-aggressive lymphoma protein 3) (Poly [ADP-ribose] polymerase 15) (PARP-15) PARP15 BAL3 Homo sapiens (Human) negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein poly-ADP-ribosylation [GO:0070212] cytoplasm [GO:0005737]; nucleus [GO:0005634] NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD+-protein ADP-ribosyltransferase activity [GO:1990404]; nucleotidyltransferase activity [GO:0016779]; transcription corepressor activity [GO:0003714] 0.88448 -0.13123 EAGSVLPAGNRGARK 0 0 8.62198 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1978 0 0 Q460N5 PAR14_HUMAN Protein mono-ADP-ribosyltransferase PARP14 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2) (Poly [ADP-ribose] polymerase 14) (PARP-14) PARP14 BAL2 KIAA1268 Homo sapiens (Human) innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; negative regulation of type II interferon-mediated signaling pathway [GO:0060336]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; positive regulation of interleukin-4-mediated signaling pathway [GO:1902216]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein poly-ADP-ribosylation [GO:0070212] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886] enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD+-protein ADP-ribosyltransferase activity [GO:1990404]; nucleotidyltransferase activity [GO:0016779]; transcription corepressor activity [GO:0003714] 0.96183 -2.4544 DDRILIEFDTLK 0 0 0 0 0 0 8.73637 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.60415 0 9.44659 0 Q494R4 CC153_HUMAN Coiled-coil domain-containing protein 153 CCDC153 Homo sapiens (Human) identical protein binding [GO:0042802] 0.96185 -2.6152 GLRGQLEACQREAAAAR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6604 0 13.3718 13.623 0 0 0 0 0 0 0 0 0 0 Q494U1 PKHN1_HUMAN Pleckstrin homology domain-containing family N member 1 (PH domain-containing family N member 1) (Cardiolipin and phosphatidic acid-binding protein) PLEKHN1 CLPABP Homo sapiens (Human) 3'-UTR-mediated mRNA destabilization [GO:0061158]; positive regulation of apoptotic process [GO:0043065]; response to hypoxia [GO:0001666] cytoskeleton [GO:0005856]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886] cardiolipin binding [GO:1901612]; phosphatidic acid binding [GO:0070300]; phosphatidylinositol phosphate binding [GO:1901981]; phosphatidylserine binding [GO:0001786] 0.89026 -0.47985 AELDRWLYHLEK 0 10.4975 0 0 0 0 0 12.2382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q494X3 ZN404_HUMAN Zinc finger protein 404 ZNF404 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.96705 -2.8402 ECGKAFGHR 0 0 0 0 0 8.92585 0 0 0 0 0 0 0 0 0 0 10.2244 0 0 0 0 0 0 0 0 0 0 Q495B1 AKD1A_HUMAN Ankyrin repeat and death domain-containing protein 1A ANKDD1A Homo sapiens (Human) signal transduction [GO:0007165] 0.9544 -1.5185 DLAGWSTMAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.56415 0 0 0 Q495C1 RN212_HUMAN Probable E3 SUMO-protein ligase RNF212 (EC 2.3.2.-) (Probable E3 SUMO-protein transferase RNF212) (RING finger protein 212) RNF212 Homo sapiens (Human) chiasma assembly [GO:0051026]; homologous chromosome pairing at meiosis [GO:0007129]; meiotic gene conversion [GO:0006311]; protein sumoylation [GO:0016925]; reciprocal meiotic recombination [GO:0007131] synaptonemal complex [GO:0000795] metal ion binding [GO:0046872]; SUMO transferase activity [GO:0019789] 0.51649 0.5943 KSVLQIEQLQSMR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.60659 0 0 0 0 0 0 0 0 0 0 0 Q495M3 S36A2_HUMAN Proton-coupled amino acid transporter 2 (Proton/amino acid transporter 2) (Solute carrier family 36 member 2) (Transmembrane domain rich protein 1) (Tramdorin-1) SLC36A2 PAT2 TRAMD1 Homo sapiens (Human) amino acid transport [GO:0006865]; glycine transport [GO:0015816]; L-alanine transport [GO:0015808]; monoatomic ion transport [GO:0006811]; proline transmembrane transport [GO:0035524]; proline transport [GO:0015824]; proton transmembrane transport [GO:1902600] endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; vacuolar membrane [GO:0005774] amino acid transmembrane transporter activity [GO:0015171]; amino acid:proton symporter activity [GO:0005280]; glycine transmembrane transporter activity [GO:0015187]; L-alanine transmembrane transporter activity [GO:0015180]; L-proline transmembrane transporter activity [GO:0015193]; proline:proton symporter activity [GO:0005297] 0.34552 0.77027 DSTFLDESPSESAGLKK 0 0 0 0 0 0 0 0 0 0 0 10.4882 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q495M9 USH1G_HUMAN pre-mRNA splicing regulator USH1G (Scaffold protein containing ankyrin repeats and SAM domain) (Usher syndrome type-1G protein) USH1G SANS Homo sapiens (Human) equilibrioception [GO:0050957]; inner ear morphogenesis [GO:0042472]; inner ear receptor cell stereocilium organization [GO:0060122]; photoreceptor cell maintenance [GO:0045494]; regulation of clathrin-dependent endocytosis [GO:2000369]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605] actin cytoskeleton [GO:0015629]; Cajal body [GO:0015030]; ciliary basal body [GO:0036064]; ciliary base [GO:0097546]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; photoreceptor cell cilium [GO:0097733]; photoreceptor connecting cilium [GO:0032391]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886] identical protein binding [GO:0042802]; spectrin binding [GO:0030507] 0.93936 -1.304 EDGGLDGVGAPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.06329 0 0 0 Q495T6 MMEL1_HUMAN "Membrane metallo-endopeptidase-like 1 (EC 3.4.24.11) (Membrane metallo-endopeptidase-like 2) (NEP2(m)) (Neprilysin II) (NEPII) (Neprilysin-2) (NEP2) (NL2) [Cleaved into: Membrane metallo-endopeptidase-like 1, soluble form (Neprilysin-2 secreted) (NEP2(s))]" MMEL1 MELL1 MMEL2 NEP2 Homo sapiens (Human) protein processing [GO:0016485]; proteolysis [GO:0006508] extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886] endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270] 0.96405 -2.108 ATVPQEER 0 0 0 0 0 0 0 0 0 0 0 0 0 16.2062 8.66242 0 0 0 0 0 0 0 0 0 9.01681 0 0 Q496H8 NRN1L_HUMAN Neuritin-like protein NRN1L UNQ2446/PRO5725 Homo sapiens (Human) neuron projection extension [GO:1990138] axon [GO:0030424]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] identical protein binding [GO:0042802] 0.6328 0.39808 LGDSMGR 0 0 0 0 0 0 0 0 0 0 0 0 9.37267 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q496J9 SV2C_HUMAN Synaptic vesicle glycoprotein 2C SV2C KIAA1054 Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; neurotransmitter transport [GO:0006836]; regulation of synaptic vesicle exocytosis [GO:2000300] dopaminergic synapse [GO:0098691]; plasma membrane [GO:0005886]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672] transmembrane transporter activity [GO:0022857] 0.94411 -1.3356 RELESERR 0 0 0 0 8.46687 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q499Z3 SLNL1_HUMAN Schlafen-like protein 1 SLFNL1 Homo sapiens (Human) ATP binding [GO:0005524] 0.91947 -0.90994 LEEKMKALMMEK 9.21169 9.01302 0 0 0 0 9.47141 9.44294 0 10.4901 0 0 0 0 0 0 0 0 0 0 0 0 0 9.90606 0 0 0 Q499Z4 ZN672_HUMAN Zinc finger protein 672 ZNF672 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]" 0.96351 -2.1 AFSVASKLALHRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.50108 0 0 0 0 0 0 0 8.23463 0 8.641 9.69818 0 Q49A17 GLTL6_HUMAN Polypeptide N-acetylgalactosaminyltransferase-like 6 (EC 2.4.1.41) (Polypeptide GalNAc transferase 17) (GalNAc-T17) (pp-GaNTase 17) (Protein-UDP acetylgalactosaminyltransferase 17) (Putative polypeptide N-acetylgalactosaminyltransferase 17) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 17) GALNTL6 GALNT17 Homo sapiens (Human) protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via threonine [GO:0018243] Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139] carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; polypeptide N-acetylgalactosaminyltransferase activity [GO:0004653] 0.9632 -2.6382 EHLKDKLEEYMAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.06356 0 0 0 9.82378 0 0 0 0 Q49A26 GLYR1_HUMAN Cytokine-like nuclear factor N-PAC (NPAC) (3-hydroxyisobutyrate dehydrogenase-like protein) (Glyoxylate reductase 1 homolog) (Nuclear protein NP60) (Nuclear protein of 60 kDa) (Nucleosome-destabilizing factor) (hNDF) (Putative oxidoreductase GLYR1) GLYR1 HIBDL NDF NP60 NPAC Homo sapiens (Human) positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase II [GO:0045944]; transcription initiation-coupled chromatin remodeling [GO:0045815] chromatin [GO:0000785]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786] chromatin binding [GO:0003682]; chromatin-protein adaptor activity [GO:0140463]; DNA binding [GO:0003677]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; nucleosome binding [GO:0031491]; oxidoreductase activity [GO:0016491] 0.89831 -0.55694 DEKDLTIPESSTVK 0 0 0 0 0 0 10.6038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q49A33 Z876P_HUMAN Putative zinc finger protein 876 ZNF876P Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.74451 0.32035 NAAKPLLNPHPLINK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.80692 0 0 0 0 Q49A88 CCD14_HUMAN Coiled-coil domain-containing protein 14 CCDC14 Homo sapiens (Human) protein localization to centrosome [GO:0071539]; substantia nigra development [GO:0021762] centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytoplasm [GO:0005737] 0.96423 -2.2693 DENKKFSSIFK 8.78087 0 11.6013 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.86672 9.28771 0 0 8.85944 0 0 0 11.0639 Q49A92 CH034_HUMAN Uncharacterized protein C8orf34 (Protein VEST-1) C8orf34 Homo sapiens (Human) 0.91472 -0.81343 QQQQQHKK 0 0 11.437 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q49AA0 ZFP69_HUMAN Zinc finger protein 69 homolog (Zinc finger protein 642) ZFP69 ZNF642 Homo sapiens (Human) lipid metabolic process [GO:0006629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of lipid metabolic process [GO:0019216] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.78565 0.25685 AYLTHHQR 0 0 0 9.46117 0 9.37443 0 0 0 12.7857 13.5333 13.4737 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q49AG3 ZBED5_HUMAN Zinc finger BED domain-containing protein 5 (Transposon-derived Buster1 transposase-like protein) ZBED5 Buster1 Homo sapiens (Human) DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.89864 -0.66602 FISNSNKITFSK 0 0 0 0 0 0 0 0 0 0 0 12.1772 0 0 0 0 0 0 0 0 0 8.54971 0 0 0 0 0 Q49AJ0 F135B_HUMAN Protein FAM135B FAM135B C8orfK32 Homo sapiens (Human) cellular lipid metabolic process [GO:0044255] 0.88987 -0.42099 ETPARAGFSSK 0 10.0573 0 0 0 0 0 0 0 11.652 0 0 9.50815 0 9.89197 0 0 10.3802 0 0 0 0 0 0 0 0 0 Q49AM1 MTEF2_HUMAN "Transcription termination factor 2, mitochondrial (Mitochondrial transcription termination factor 2) (mTERF2) (Mitochondrial transcription termination factor-like protein) (mTERF-like) (mTERFL) (mTERF domain-containing protein 3, mitochondrial)" MTERF2 MTERFD3 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; termination of mitochondrial transcription [GO:0006393] mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739] DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; nucleic acid binding [GO:0003676] 0.9337 -1.2901 LYKCSVDIRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.20296 0 0 0 0 0 0 Q49AS3 L37A5_HUMAN Putative protein LRRC37A5P (Leucine-rich repeat-containing 37 member A5 pseudogene) LRRC37A5P C9orf29 Homo sapiens (Human) 0.80238 0.24048 LLSEQQELR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.52918 0 0 0 0 Q49MG5 MAP9_HUMAN Microtubule-associated protein 9 (Aster-associated protein) MAP9 ASAP Homo sapiens (Human) mitotic cytokinesis [GO:0000281]; mitotic spindle assembly [GO:0090307]; regulation of mitotic centrosome separation [GO:0046602]; regulation of mitotic cytokinesis [GO:1902412]; regulation of mitotic spindle organization [GO:0060236] astral microtubule [GO:0000235]; axon [GO:0030424]; cytoplasm [GO:0005737]; mitotic spindle [GO:0072686]; mitotic spindle midzone [GO:1990023]; spindle midzone [GO:0051233] microtubule binding [GO:0008017] 0.95264 -1.4597 DEEFEKDKIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2536 11.497 0 0 0 0 0 0 0 9.13945 0 Q49MI3 CERKL_HUMAN Ceramide kinase-like protein CERKL Homo sapiens (Human) negative regulation of apoptotic process [GO:0043066]; phosphorylation [GO:0016310]; sphingolipid biosynthetic process [GO:0030148]; sphingolipid metabolic process [GO:0006665] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750] lipid kinase activity [GO:0001727]; sphingolipid binding [GO:0046625] 0.96683 -2.8261 RCSVKQQR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.95884 0 0 0 0 0 0 0 0 0 10.6874 0 0 0 Q4AC94 C2CD3_HUMAN C2 domain-containing protein 3 C2CD3 Homo sapiens (Human) brain development [GO:0007420]; centriole elongation [GO:0061511]; cilium assembly [GO:0060271]; embryonic digit morphogenesis [GO:0042733]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; neural plate axis specification [GO:0021997]; neural tube development [GO:0021915]; non-motile cilium assembly [GO:1905515]; protein localization to centrosome [GO:0071539]; protein processing [GO:0016485]; regulation of proteolysis [GO:0030162]; regulation of smoothened signaling pathway [GO:0008589] centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytosol [GO:0005829] 0.88427 -0.15554 DALQTEPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1226 0 Q4AC99 1A1L2_HUMAN Probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2 (ACC synthase-like protein 2) ACCSL Homo sapiens (Human) amino acid metabolic process [GO:0006520]; biosynthetic process [GO:0009058] pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483] 0.92118 -1.1054 LLYCRFLDNK 0 0 0 0 0 0 0 0 0 0 0 0 8.435 9.7912 0 0 0 9.61475 0 0 9.47978 0 0 0 0 9.04519 0 Q4AE62 GTDC1_HUMAN Glycosyltransferase-like domain-containing protein 1 (Mannosyltransferase-like protein Xa) (Mat-Xa) GTDC1 Homo sapiens (Human) glycosyltransferase activity [GO:0016757] 0.86033 0.093256 LQNFCKRPDIIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.62172 0 0 0 Q4FZB7 KMT5B_HUMAN Histone-lysine N-methyltransferase KMT5B (Lysine N-methyltransferase 5B) (Lysine-specific methyltransferase 5B) (Suppressor of variegation 4-20 homolog 1) (Su(var)4-20 homolog 1) (Suv4-20h1) ([histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B) (EC 2.1.1.362) ([histone H4]-lysine20 N-methyltransferase KMT5B) (EC 2.1.1.361) KMT5B SUV420H1 CGI-85 Homo sapiens (Human) DNA repair [GO:0006281]; histone H4-K20 dimethylation [GO:0034772]; muscle organ development [GO:0007517]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; positive regulation of isotype switching [GO:0045830] "condensed chromosome, centromeric region [GO:0000779]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]" chromatin binding [GO:0003682]; histone H4K20 methyltransferase activity [GO:0042799]; histone H4K20 monomethyltransferase activity [GO:0140944]; histone H4K20me methyltransferase activity [GO:0140941]; histone methyltransferase activity [GO:0042054]; metal ion binding [GO:0046872]; S-adenosyl-L-methionine binding [GO:1904047] 0.96704 -2.838 GAHSQGESSPCTYITRRSVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1765 0 0 0 0 0 10.2397 0 0 0 0 0 Q4G0A6 MINY4_HUMAN Probable ubiquitin carboxyl-terminal hydrolase MINDY-4 (EC 3.4.19.12) (Probable deubiquitinating enzyme MINDY-4) MINDY4 C7orf67 FAM188B Homo sapiens (Human) protein K48-linked deubiquitination [GO:0071108] cysteine-type deubiquitinase activity [GO:0004843]; K48-linked deubiquitinase activity [GO:1990380] 0.92324 -1.0767 LEDVEDELIR 0 0 0 0 9.16862 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.75912 0 0 0 0 0 0 0 Q4G0J3 LARP7_HUMAN La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S) LARP7 HDCMA18P Homo sapiens (Human) "box C/D RNA 3'-end processing [GO:0000494]; cell differentiation [GO:0030154]; mRNA processing [GO:0006397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; negative regulation of viral transcription [GO:0032897]; positive regulation of protein localization to Cajal body [GO:1904871]; positive regulation of snRNA transcription by RNA polymerase II [GO:1905382]; regulation of mRNA splicing, via spliceosome [GO:0048024]; RNA splicing [GO:0008380]; spermatogenesis [GO:0007283]; U6 2'-O-snRNA methylation [GO:1990438]" 7SK snRNP [GO:0120259]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; polysome [GO:0005844]; ribonucleoprotein complex [GO:1990904] 7SK snRNA binding [GO:0097322]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; U6 snRNA binding [GO:0017070] 0.9655 -2.3663 ETESGNQEK 0 0 8.53329 0 0 10.5918 0 0 0 0 0 0 9.85471 0 0 0 0 0 0 0 11.8019 0 0 0 0 0 0 Q4G0M1 ERFE_HUMAN Erythroferrone (Complement C1q tumor necrosis factor-related protein 15) (Myonectin) ERFE C1QTNF15 CTRP15 FAM132B Homo sapiens (Human) establishment of localization in cell [GO:0051649]; fatty acid transport [GO:0015908]; intracellular iron ion homeostasis [GO:0006879]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of fatty acid transport [GO:2000193]; positive regulation of glucose import [GO:0046326]; positive regulation of insulin receptor signaling pathway [GO:0046628]; regulation of fatty acid metabolic process [GO:0019217] extracellular region [GO:0005576]; extracellular space [GO:0005615] hormone activity [GO:0005179]; identical protein binding [GO:0042802] 0.90654 -0.7124 DAWMLFVRQSDK 0 0 0 0 0 0 0 0 0 0 0 10.3634 0 0 0 0 0 0 0 0 0 0 0 0 11.3215 0 9.15957 Q4G0N4 NAKD2_HUMAN "NAD kinase 2, mitochondrial (EC 2.7.1.23) (Mitochondrial NAD kinase) (NAD kinase domain-containing protein 1, mitochondrial)" NADK2 C5orf33 MNADK NADKD1 Homo sapiens (Human) NAD metabolic process [GO:0019674]; NADP biosynthetic process [GO:0006741]; phosphorylation [GO:0016310] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; NAD+ kinase activity [GO:0003951]; protein homodimerization activity [GO:0042803] 0.63169 0.40388 LGGDGGGR 0 0 0 0 0 0 0 0 0 11.1219 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q4G0N8 SL9C1_HUMAN Sodium/hydrogen exchanger 10 (Na(+)/H(+) exchanger 10) (NHE-10) (Solute carrier family 9 member 10) (Solute carrier family 9 member C1) (Sperm-specific Na(+)/H(+) exchanger) (sNHE) SLC9C1 SLC9A10 Homo sapiens (Human) cell differentiation [GO:0030154]; flagellated sperm motility [GO:0030317]; potassium ion transmembrane transport [GO:0071805]; regulation of intracellular pH [GO:0051453]; sodium ion import across plasma membrane [GO:0098719]; spermatogenesis [GO:0007283] motile cilium [GO:0031514]; plasma membrane [GO:0005886] monoatomic ion channel activity [GO:0005216]; potassium:proton antiporter activity [GO:0015386]; sodium:proton antiporter activity [GO:0015385] 0.89701 -0.54556 TKEEINVMLNMATEILK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.93097 0 0 0 0 0 0 0 0 10.2184 Q4G0P3 HYDIN_HUMAN Hydrocephalus-inducing protein homolog HYDIN HYDIN1 KIAA1864 Homo sapiens (Human) axonemal central apparatus assembly [GO:1904158]; cilium movement [GO:0003341]; epithelial cell development [GO:0002064]; trachea development [GO:0060438]; ventricular system development [GO:0021591] axonemal central apparatus [GO:1990716]; axonemal central pair projection [GO:1990718]; axoneme [GO:0005930] 0.96242 -2.5074 ARFKISNVGK 0 10.3285 0 0 0 0 0 0 0 0 0 0 0 0 11.8056 0 15.014 0 9.48844 8.70401 0 0 0 0 11.9917 0 0 Q4G0S4 C27C1_HUMAN "Cytochrome P450 27C1 (EC 1.14.19.53) (All-trans retinol 3,4-desaturase)" CYP27C1 Homo sapiens (Human) retinal metabolic process [GO:0042574]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572] intracellular membrane-bounded organelle [GO:0043231]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739] "11-cis retinal binding [GO:0005502]; 11-cis-retinal 3,4-desaturase activity [GO:0061899]; all-trans retinal 3,4-desaturase activity [GO:0061897]; all-trans retinal binding [GO:0005503]; all-trans retinoic acid 3,4-desaturase activity [GO:0061898]; all-trans retinol 3,4-desaturase activity [GO:0061896]; all-trans-retinol binding [GO:1904768]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; retinoic acid binding [GO:0001972]" 0.92381 -1.0361 EIVKNLGER 0 0 0 0 0 0 0 0 0 0 0 0 0 12.2572 0 0 0 11.7493 0 0 0 0 0 0 0 0 10.262 Q4G0S7 CC152_HUMAN Coiled-coil domain-containing protein 152 CCDC152 Chr5_400 Homo sapiens (Human) 0.96783 -3.6873 LSVGKDSHLK 0 0 0 0 0 0 0 9.25368 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q4G0T1 SRCRM_HUMAN Scavenger receptor cysteine-rich domain-containing protein SCART1 (Scavenger receptor family member expressed on T cells 1) SCART1 Homo sapiens (Human) T cell mediated immunity [GO:0002456] brush border [GO:0005903]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886] scavenger receptor activity [GO:0005044] 0.92152 -1.1045 VLDDAWDLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4476 0 0 0 0 0 Q4G0X4 KCD21_HUMAN BTB/POZ domain-containing protein KCTD21 (KCASH2 protein) (Potassium channel tetramerization domain-containing protein 21) KCTD21 Homo sapiens (Human) negative regulation of smoothened signaling pathway [GO:0045879]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] cullin family protein binding [GO:0097602]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802] 0.87077 0.052636 DGKVFRYILNFLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.53611 0 0 8.6799 0 0 0 0 0 0 Q4G0X9 CCD40_HUMAN Coiled-coil domain-containing protein 40 CCDC40 KIAA1640 Homo sapiens (Human) axonemal dynein complex assembly [GO:0070286]; axoneme assembly [GO:0035082]; cilium movement [GO:0003341]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; flagellated sperm motility [GO:0030317]; heart looping [GO:0001947]; inner dynein arm assembly [GO:0036159]; lung development [GO:0030324]; motile cilium assembly [GO:0044458]; regulation of cilium beat frequency [GO:0003356] axoneme [GO:0005930]; cilium [GO:0005929]; cytoplasm [GO:0005737]; extracellular region [GO:0005576] 0.93828 -1.2942 KLNMLMNK 0 0 8.55371 0 0 9.74403 8.70404 8.44415 0 0 0 9.33217 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q4G148 GXLT1_HUMAN Glucoside xylosyltransferase 1 (EC 2.4.2.42) (Glycosyltransferase 8 domain-containing protein 3) GXYLT1 GLT8D3 Homo sapiens (Human) O-glycan processing [GO:0016266] membrane [GO:0016020] "UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase activity [GO:0140563]; UDP-xylosyltransferase activity [GO:0035252]" 0.95574 -1.5475 KLFKPCASQR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4206 0 0 0 0 0 0 0 0 0 0 0 0 0 Q4G176 ACSF3_HUMAN "Malonate--CoA ligase ACSF3, mitochondrial (EC 6.2.1.76) (Acyl-CoA synthetase family member 3)" ACSF3 PSEC0197 Homo sapiens (Human) fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; malonate catabolic process [GO:0090410] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] acid-thiol ligase activity [GO:0016878]; ATP binding [GO:0005524]; malonyl-CoA synthetase activity [GO:0090409]; very long-chain fatty acid-CoA ligase activity [GO:0031957] 0.95516 -1.5657 ELKEWAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.049 0 0 9.91722 0 0 0 0 0 0 Q4J6C6 PPCEL_HUMAN Prolyl endopeptidase-like (EC 3.4.21.-) (Prolylendopeptidase-like) PREPL KIAA0436 Homo sapiens (Human) "Golgi to plasma membrane protein transport [GO:0043001]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; retrograde transport, endosome to Golgi [GO:0042147]" cytoskeleton [GO:0005856]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; trans-Golgi network [GO:0005802] peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252] 0.96895 -3.3436 FLYEELGLDSTSVFEDLK 9.96636 11.0449 10.8542 12.055 0 0 0 0 0 0 10.068 11.8736 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q4JDL3 PTN20_HUMAN Tyrosine-protein phosphatase non-receptor type 20 (hPTPN20) (EC 3.1.3.48) PTPN20 PTPN20A PTPN20B Homo sapiens (Human) protein dephosphorylation [GO:0006470] centriolar satellite [GO:0034451]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; microtubule [GO:0005874]; nucleoplasm [GO:0005654] phosphoprotein phosphatase activity [GO:0004721] 0.89831 -0.55393 DILPYDSTRVPLGK 0 0 0 0 0 0 0 0 0 0 0 0 9.58318 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q4KMG9 TM52B_HUMAN Transmembrane protein 52B TMEM52B C12orf59 UNQ5927/PRO19821 Homo sapiens (Human) extracellular exosome [GO:0070062]; membrane [GO:0016020] 0.17175 0.96745 APDLPPVPEEK 11.8169 11.6157 11.3545 11.5376 11.6473 11.5118 11.24 11.2033 10.9937 12.819 13.1399 12.8275 10.3383 10.2851 10.522 10.8165 10.9733 10.8659 0 0 0 0 0 0 0 0 0 Q4KMP7 TB10B_HUMAN TBC1 domain family member 10B (Rab27A-GAP-beta) TBC1D10B FP2461 Homo sapiens (Human) "activation of GTPase activity [GO:0090630]; regulation of GTPase activity [GO:0043087]; retrograde transport, endosome to Golgi [GO:0042147]" cytosol [GO:0005829]; plasma membrane [GO:0005886] GTPase activator activity [GO:0005096] 0.95968 -1.9225 AIHEERRR 0 0 0 0 0 0 0 0 0 0 0 9.53249 0 8.49305 0 0 0 0 0 0 0 0 0 0 0 10.4976 9.02276 Q4KMQ1 TPRN_HUMAN Taperin TPRN C9orf75 Homo sapiens (Human) auditory receptor cell stereocilium organization [GO:0060088]; sensory perception of sound [GO:0007605]; stereocilium maintenance [GO:0120045] stereocilium [GO:0032420]; stereocilium base [GO:0120044] phosphatase binding [GO:0019902] 0.92607 -1.1799 ALASLRANSR 0 0 0 0 9.12866 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.455 0 0 0 Q4KMQ2 ANO6_HUMAN Anoctamin-6 (Small-conductance calcium-activated nonselective cation channel) (SCAN channel) (Transmembrane protein 16F) ANO6 TMEM16F Homo sapiens (Human) "activation of blood coagulation via clotting cascade [GO:0002543]; bleb assembly [GO:0032060]; blood coagulation [GO:0007596]; calcium activated phosphatidylcholine scrambling [GO:0061590]; calcium activated phosphatidylserine scrambling [GO:0061589]; calcium ion transmembrane transport [GO:0070588]; chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; monoatomic cation transport [GO:0006812]; monoatomic ion transmembrane transport [GO:0034220]; negative regulation of cell volume [GO:0045794]; phosphatidylserine exposure on blood platelet [GO:0097045]; plasma membrane phospholipid scrambling [GO:0017121]; pore complex assembly [GO:0046931]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of monoatomic ion transmembrane transport [GO:0034767]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of potassium ion export across plasma membrane [GO:1903766]; purinergic nucleotide receptor signaling pathway [GO:0035590]; sodium ion transmembrane transport [GO:0035725]" cell surface [GO:0009986]; chloride channel complex [GO:0034707]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821] calcium activated cation channel activity [GO:0005227]; chloride channel activity [GO:0005254]; intracellular calcium activated chloride channel activity [GO:0005229]; metal ion binding [GO:0046872]; phospholipid scramblase activity [GO:0017128]; protein dimerization activity [GO:0046983]; voltage-gated chloride channel activity [GO:0005247]; voltage-gated monoatomic ion channel activity [GO:0005244] 0.96949 -3.4596 ETNKKGTNEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7103 0 0 9.90591 0 0 0 Q4KMZ1 IQCC_HUMAN IQ domain-containing protein C IQCC Homo sapiens (Human) 0.96371 -2.6518 KQRTIPWR 0 0 0 0 0 0 0 0 0 9.1172 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q4KWH8 PLCH1_HUMAN "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-eta-1) (Phospholipase C-eta-1) (PLC-eta-1) (Phospholipase C-like protein 3) (PLC-L3)" PLCH1 KIAA1069 PLCL3 Homo sapiens (Human) lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; release of sequestered calcium ion into cytosol [GO:0051209] cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; calcium-dependent phospholipase C activity [GO:0050429]; phosphatidylinositol phospholipase C activity [GO:0004435] 0.95999 -1.9069 DIEGKENSLAEDK 0 0 0 0 0 0 0 0 0 10.4525 0 10.7175 10.0963 0 0 0 0 0 0 9.21434 0 0 0 8.29696 0 0 0 Q4L180 FIL1L_HUMAN Filamin A-interacting protein 1-like (130 kDa GPBP-interacting protein) (90 kDa GPBP-interacting protein) (Protein down-regulated in ovarian cancer 1) (DOC-1) FILIP1L COL4A3BPIP DOC1 GIP90 Homo sapiens (Human) cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleus [GO:0005634] 0.96931 -4.1768 EVDALKEK 0 0 0 0 0 0 0 9.97799 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q4L235 ACSF4_HUMAN Beta-alanine-activating enzyme (EC 6.2.1.-) (Acyl-CoA synthetase family member 4) (Protein NRPS998) AASDH ACSF4 U26 HSPC318 Homo sapiens (Human) amino acid activation for nonribosomal peptide biosynthetic process [GO:0043041]; beta-alanine metabolic process [GO:0019482]; fatty acid metabolic process [GO:0006631] acid-thiol ligase activity [GO:0016878]; ATP binding [GO:0005524] 0.90526 -0.72108 LHWKNTEVNLMLNDGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.50472 0 0 0 9.13661 0 0 0 Q4LDG9 DNAL1_HUMAN Dynein axonemal light chain 1 (LC1) DNAL1 C14orf168 Homo sapiens (Human) outer dynein arm assembly [GO:0036158] cytoplasm [GO:0005737]; microtubule [GO:0005874]; outer dynein arm [GO:0036157] alpha-tubulin binding [GO:0043014]; dynein heavy chain binding [GO:0045504] 0.87229 0.037161 LYAQIPPIEK 0 0 0 0 0 0 0 0 0 0 8.95716 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q4LE39 ARI4B_HUMAN AT-rich interactive domain-containing protein 4B (ARID domain-containing protein 4B) (180 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p180) (Breast cancer-associated antigen BRCAA1) (Histone deacetylase complex subunit SAP180) (Retinoblastoma-binding protein 1-like 1) ARID4B BRCAA1 RBBP1L1 RBP1L1 SAP180 Homo sapiens (Human) DNA methylation [GO:0006306]; establishment of Sertoli cell barrier [GO:0097368]; negative regulation of cell migration [GO:0030336]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression by genomic imprinting [GO:0006349]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; transcription by RNA polymerase II [GO:0006366] cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Sin3 complex [GO:0016580] transcription cis-regulatory region binding [GO:0000976] 0.96971 -4.1628 DKDEKYSPK 0 0 0 0 0 0 0 0 0 10.3108 9.31793 9.13111 0 0 0 0 0 0 0 0 0 9.47547 0 10.3226 0 11.385 0 Q4UJ75 A20A4_HUMAN Putative ankyrin repeat domain-containing protein 20A4 (Ankyrin repeat domain-containing protein 20A4 pseudogene) ANKRD20A4P ANKRD20A4 Homo sapiens (Human) 0.96431 -2.3893 CLARRSGELDALDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.88801 0 0 0 0 0 0 0 0 0 0 Q4V328 GRAP1_HUMAN GRIP1-associated protein 1 (GRASP-1) [Cleaved into: GRASP-1 C-terminal chain (30kDa C-terminus form)] GRIPAP1 KIAA1167 Homo sapiens (Human) "negative regulation of receptor clustering [GO:1903910]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; regulation of modification of synaptic structure [GO:1905244]; regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0099152]; regulation of recycling endosome localization within postsynapse [GO:0099158]" axon [GO:0030424]; blood microparticle [GO:0072562]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of postsynaptic early endosome membrane [GO:0098998]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; postsynaptic density [GO:0014069]; postsynaptic recycling endosome [GO:0098837]; presynaptic membrane [GO:0042734]; recycling endosome membrane [GO:0055038] guanyl-nucleotide exchange factor activity [GO:0005085]; identical protein binding [GO:0042802]; ionotropic glutamate receptor binding [GO:0035255] 0.96921 -4.5769 ETLFNDSR 0 11.1818 0 0 0 0 0 10.4228 0 0 0 0 0 0 0 0 0 0 10.0105 0 0 0 0 0 10.4762 0 0 Q4VC44 FWCH1_HUMAN FLYWCH-type zinc finger-containing protein 1 FLYWCH1 KIAA1552 Homo sapiens (Human) DNA damage response [GO:0006974]; negative regulation of transcription by RNA polymerase II [GO:0000122] cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; pericentric heterochromatin [GO:0005721]; transcription regulator complex [GO:0005667] DNA binding [GO:0003677]; metal ion binding [GO:0046872]; transcription coactivator binding [GO:0001223]; transcription corepressor activity [GO:0003714] 0.9617 -2.6035 AVGDKVYWK 0 13.4579 13.1616 9.87791 0 0 11.6408 10.4625 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q4VCS5 AMOT_HUMAN Angiomotin AMOT KIAA1071 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; angiogenesis [GO:0001525]; blood vessel endothelial cell migration [GO:0043534]; cell migration involved in gastrulation [GO:0042074]; cell-cell junction assembly [GO:0007043]; chemotaxis [GO:0006935]; establishment of cell polarity involved in ameboidal cell migration [GO:0003365]; establishment of epithelial cell polarity [GO:0090162]; gastrulation with mouth forming second [GO:0001702]; hippo signaling [GO:0035329]; in utero embryonic development [GO:0001701]; negative regulation of angiogenesis [GO:0016525]; negative regulation of GTPase activity [GO:0034260]; negative regulation of vascular permeability [GO:0043116]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell size [GO:0045793]; positive regulation of embryonic development [GO:0040019]; positive regulation of stress fiber assembly [GO:0051496]; protein localization [GO:0008104]; regulation of cell migration [GO:0030334]; regulation of small GTPase mediated signal transduction [GO:0051056]; vasculogenesis [GO:0001570] actin filament [GO:0005884]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endocytic vesicle [GO:0030139]; external side of plasma membrane [GO:0009897]; lamellipodium [GO:0030027]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stress fiber [GO:0001725] angiostatin binding [GO:0043532]; signaling receptor activity [GO:0038023] 0.92443 -1.0666 LEAELATAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.93403 0 0 0 0 11.2999 0 0 10.4547 0 Q4VNC0 AT135_HUMAN Probable cation-transporting ATPase 13A5 (EC 7.2.2.-) (P5-ATPase isoform 5) ATP13A5 UNQ488/PRO1004 Homo sapiens (Human) intracellular calcium ion homeostasis [GO:0006874]; monoatomic ion transmembrane transport [GO:0034220]; polyamine transmembrane transport [GO:1902047] late endosome membrane [GO:0031902]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled monoatomic cation transmembrane transporter activity [GO:0019829]; metal ion binding [GO:0046872]; P-type transmembrane transporter activity [GO:0140358]; polyamine transmembrane transporter activity [GO:0015203] 0.89809 -0.68365 SQYRTWQK 0 0 0 0 0 0 9.21827 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q4VNC1 AT134_HUMAN Probable cation-transporting ATPase 13A4 (EC 7.2.2.-) (P5-ATPase isoform 4) ATP13A4 UNQ3052/PRO9871 Homo sapiens (Human) intracellular calcium ion homeostasis [GO:0006874]; monoatomic ion transmembrane transport [GO:0034220]; polyamine transmembrane transport [GO:1902047] early endosome membrane [GO:0031901]; endoplasmic reticulum membrane [GO:0005789]; late endosome membrane [GO:0031902]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled monoatomic cation transmembrane transporter activity [GO:0019829]; metal ion binding [GO:0046872]; P-type transmembrane transporter activity [GO:0140358]; polyamine transmembrane transporter activity [GO:0015203] 0.87678 -0.006142 GIFCISPQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.11056 0 Q4VX76 SYTL3_HUMAN Synaptotagmin-like protein 3 (Exophilin-6) SYTL3 SLP3 Homo sapiens (Human) exocytosis [GO:0006887]; intracellular protein transport [GO:0006886] exocytic vesicle [GO:0070382]; plasma membrane [GO:0005886] calcium-dependent phospholipid binding [GO:0005544]; neurexin family protein binding [GO:0042043]; small GTPase binding [GO:0031267] 0.87122 0.052934 GTHAWKCTVCFEDR 0 0 0 0 0 0 0 0 0 13.5275 0 0 0 0 0 0 12.5566 12.1364 0 0 0 0 0 0 0 10.4978 0 Q4VXA5 KHDC1_HUMAN KH homology domain-containing protein 1 KHDC1 C6orf147 C6orf148 Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919] cytoplasm [GO:0005737]; membrane [GO:0016020] RNA binding [GO:0003723] 0.85135 0.16103 SEQSMDMGTSALSK 0 0 0 9.27233 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q4VXU2 PAP1L_HUMAN Polyadenylate-binding protein 1-like PABPC1L C20orf119 Homo sapiens (Human) cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266] 0.97001 -3.267 AVVHMNGK 0 0 0 0 0 0 9.36337 0 0 0 9.65796 0 0 9.47861 0 0 0 0 9.12717 0 0 0 0 0 0 0 0 Q4W4Y0 CN028_HUMAN Uncharacterized protein C14orf28 (Dopamine receptor-interacting protein 1) C14orf28 DRIP1 Homo sapiens (Human) 0.81804 0.22016 LAVNELFCSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.6331 0 0 0 0 Q4ZG55 GREB1_HUMAN Protein GREB1 (Gene regulated in breast cancer 1 protein) GREB1 KIAA0575 Homo sapiens (Human) extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654] 0.88484 -0.21523 AEGRVDGFHPR 11.5313 0 10.4211 0 0 0 9.96996 9.96411 0 0 9.68657 10.0641 0 0 0 0 0 0 10.5473 0 0 0 0 0 0 0 0 Q4ZHG4 FNDC1_HUMAN Fibronectin type III domain-containing protein 1 (Activation-associated cDNA protein) (Expressed in synovial lining protein) FNDC1 FNDC2 KIAA1866 MEL4B3 Homo sapiens (Human) extracellular region [GO:0005576] 0.96862 -6.5619 ARMPALPR 0 0 0 11.1583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3132 9.9397 0 Q502W6 VWA3B_HUMAN von Willebrand factor A domain-containing protein 3B (VWA domain-containing protein 3B) VWA3B Homo sapiens (Human) cytosol [GO:0005829]; nucleoplasm [GO:0005654] 0.96899 -6.8435 ALSQEEK 0 8.63655 9.30975 0 0 0 0 0 0 0 0 0 8.53002 0 0 0 0 0 0 9.70127 0 0 0 0 8.43738 0 0 Q502W7 CCD38_HUMAN Coiled-coil domain-containing protein 38 CCDC38 Homo sapiens (Human) centrosome [GO:0005813]; cytoplasm [GO:0005737] 0.9596 -1.827 AQASKSKANIILPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5022 0 0 0 0 0 Q504Q3 PAN2_HUMAN PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (EC 3.1.13.4) (Inactive ubiquitin carboxyl-terminal hydrolase 52) (PAB1P-dependent poly(A)-specific ribonuclease) (Poly(A)-nuclease deadenylation complex subunit 2) (PAN deadenylation complex subunit 2) PAN2 KIAA0710 USP52 Homo sapiens (Human) mRNA processing [GO:0006397]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606] cytosol [GO:0005829]; nucleus [GO:0005634]; P-body [GO:0000932]; PAN complex [GO:0031251] 3'-5'-RNA exonuclease activity [GO:0000175]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; poly(A)-specific ribonuclease activity [GO:0004535] 0.9637 -2.2354 FLKVYDLR 0 9.55334 9.60099 0 9.03304 0 12.275 0 0 0 0 0 0 0 9.24888 10.7999 12.2951 0 0 0 0 0 0 0 0 0 0 Q504T8 MIDN_HUMAN Midnolin (Midbrain nucleolar protein) MIDN Homo sapiens (Human) negative regulation of glucokinase activity [GO:0033132]; negative regulation of insulin secretion [GO:0046676] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleus [GO:0005634] kinase binding [GO:0019900] 0.91641 -0.77443 GDPSIASPVSSPCRPVSSAAR 0 0 0 9.50609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q504Y3 ZCPW2_HUMAN Zinc finger CW-type PWWP domain protein 2 ZCWPW2 Homo sapiens (Human) nucleus [GO:0005634] methylated histone binding [GO:0035064]; zinc ion binding [GO:0008270] 0.55919 0.54209 AGECIEDITNK 10.6554 0 0 0 0 0 0 0 10.6345 0 0 11.5821 0 0 0 8.96443 0 0 0 0 0 0 0 0 0 0 0 Q50LG9 LRC24_HUMAN Leucine-rich repeat-containing protein 24 LRRC24 Homo sapiens (Human) positive regulation of synapse assembly [GO:0051965] cell surface [GO:0009986]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; membrane [GO:0016020] 0.91471 -0.82905 EALQPLASLQVLRLTENPWR 0 9.49551 0 0 10.7617 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q52LC2 VAS1L_HUMAN V-type proton ATPase subunit S1-like protein (Vacuolar proton pump subunit S1-like protein) ATP6AP1L Homo sapiens (Human) regulation of cellular pH [GO:0030641] proton-transporting V-type ATPase complex [GO:0033176] 0.23688 0.85171 VLKLVLKTAK 11.4485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q52LD8 RFTN2_HUMAN Raftlin-2 (Raft-linking protein 2) RFTN2 C2orf11 Homo sapiens (Human) dsRNA transport [GO:0033227]; response to exogenous dsRNA [GO:0043330] plasma membrane [GO:0005886] 0.95104 -1.413 HDSEGNLATK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.56276 0 0 0 0 0 Q52LJ0 FA98B_HUMAN Protein FAM98B FAM98B Homo sapiens (Human) "positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; protein methylation [GO:0006479]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]" cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tRNA-splicing ligase complex [GO:0072669] identical protein binding [GO:0042802]; protein methyltransferase activity [GO:0008276]; RNA binding [GO:0003723] 0.96973 -5.1322 INDALSCEYECR 0 0 0 0 0 0 0 0 0 8.30816 8.26922 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q52LW3 RHG29_HUMAN Rho GTPase-activating protein 29 (PTPL1-associated RhoGAP protein 1) (Rho-type GTPase-activating protein 29) ARHGAP29 PARG1 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266] cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991] GTPase activator activity [GO:0005096]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165] 0.96932 -4.5138 KQNALGK 0 0 0 0 0 0 0 0 0 0 8.96359 0 0 0 0 0 10.0796 10.5308 0 9.38769 0 0 9.60392 0 9.73091 9.69573 0 Q52M75 CE027_HUMAN Putative uncharacterized protein encoded by LINC01554 (Protein FIS) LINC01554 C5orf27 Homo sapiens (Human) 0.8721 0.029992 LASRPQGGR 8.94187 0 0 0 0 9.9993 0 0 0 10.5366 10.469 0 0 0 0 0 0 0 0 9.95054 0 0 0 0 0 0 0 Q52MB2 CC184_HUMAN Coiled-coil domain-containing protein 184 CCDC184 C12orf68 Homo sapiens (Human) cytoplasm [GO:0005737] 0.59571 0.4445 DPEDEEEEEEEK 13.568 13.4423 13.8823 8.4045 8.36014 8.49574 13.7359 14.0219 14.1116 11.9658 11.9543 11.8414 9.08329 10.0396 10.2627 10.4397 10.5226 10.4291 0 0 0 0 0 0 0 0 0 Q53EL9 SEZ6_HUMAN Seizure protein 6 homolog (SEZ-6) (hSEZ-6) SEZ6 Homo sapiens (Human) adult locomotory behavior [GO:0008344]; cerebellar Purkinje cell layer development [GO:0021680]; excitatory postsynaptic potential [GO:0060079]; regulation of dendrite development [GO:0050773]; regulation of protein kinase C signaling [GO:0090036]; synapse maturation [GO:0060074] apical dendrite [GO:0097440]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] 0.78135 0.26136 FHCATGYQLK 0 0 0 0 9.33481 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.9806 0 0 0 0 Q53EV4 LRC23_HUMAN Leucine-rich repeat-containing protein 23 (Leucine-rich protein B7) LRRC23 LRPB7 Homo sapiens (Human) cytoplasm [GO:0005737]; cytosol [GO:0005829] 0.78406 0.26008 NLYLAQNMLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.97656 Q53EZ4 CEP55_HUMAN Centrosomal protein of 55 kDa (Cep55) (Up-regulated in colon cancer 6) CEP55 C10orf3 URCC6 Homo sapiens (Human) cranial skeletal system development [GO:1904888]; establishment of protein localization [GO:0045184]; midbody abscission [GO:0061952]; mitotic cytokinesis [GO:0000281]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] centriole [GO:0005814]; centrosome [GO:0005813]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; Flemming body [GO:0090543]; intercellular bridge [GO:0045171]; membrane [GO:0016020]; midbody [GO:0030496] identical protein binding [GO:0042802] 0.96811 -2.7716 ADVQHLEDDR 0 0 0 0 0 0 0 0 0 0 0 9.20406 0 10.6519 0 0 0 0 0 0 0 0 10.0937 0 0 0 0 Q53F19 NCBP3_HUMAN Nuclear cap-binding protein subunit 3 (Protein ELG) NCBP3 C17orf85 Homo sapiens (Human) 7-methylguanosine mRNA capping [GO:0006370]; defense response to virus [GO:0051607]; mRNA export from nucleus [GO:0006406]; mRNA transcription by RNA polymerase II [GO:0042789]; snRNA export from nucleus [GO:0006408] cytoplasm [GO:0005737]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; RNA cap binding complex [GO:0034518] mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339] 0.9603 -1.8066 AFSSNPVVRR 0 0 0 0 0 0 0 11.0636 0 0 8.96359 0 10.9671 0 0 0 0 0 12.3278 0 0 0 0 0 0 0 0 Q53F39 MPPE1_HUMAN Metallophosphoesterase 1 (EC 3.1.-.-) (Post-GPI attachment to proteins factor 5) MPPE1 PGAP5 PP579 Homo sapiens (Human) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; GPI anchor biosynthetic process [GO:0006506] cis-Golgi network [GO:0005801]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654] GPI anchor binding [GO:0034235]; GPI-mannose ethanolamine phosphate phosphodiesterase activity [GO:0062050]; manganese ion binding [GO:0030145] 0.16134 0.99768 EARGSSR 0 0 0 12.0612 8.45418 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.69627 0 9.28033 0 0 0 0 Q53FA7 QORX_HUMAN Quinone oxidoreductase PIG3 (EC 1.6.5.5) (NADPH:quinone reductase PIG3) (Tumor protein p53-inducible protein 3) (Protein PIG3) (p53-induced gene 3 protein) TP53I3 PIG3 Homo sapiens (Human) NADP metabolic process [GO:0006739] cytosol [GO:0005829] NADPH binding [GO:0070402]; NADPH:quinone reductase activity [GO:0003960]; protein homodimerization activity [GO:0042803]; quinone binding [GO:0048038] 0.83248 0.20172 GAGVNLILDCIGGSYWEK 0 0 0 0 11.5451 0 0 0 0 12.5819 0 12.6075 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q53FD0 ZC21C_HUMAN Zinc finger C2HC domain-containing protein 1C ZC2HC1C C14orf140 FAM164C Homo sapiens (Human) metal ion binding [GO:0046872] 0.76497 0.28418 DPVSEPSVEK 15.9521 16.011 0 11.3286 11.7892 0 15.6155 15.9668 15.8637 15.3799 15.5053 15.3857 13.4997 13.6251 13.7205 14.2299 0 14.6588 0 0 0 0 0 0 0 0 0 Q53FZ2 ACSM3_HUMAN "Acyl-coenzyme A synthetase ACSM3, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 3) (Butyrate--CoA ligase 3) (Butyryl-coenzyme A synthetase 3) (Middle-chain acyl-CoA synthetase 3) (Propionate--CoA ligase) (EC 6.2.1.17) (Protein SA homolog)" ACSM3 SAH Homo sapiens (Human) acyl-CoA metabolic process [GO:0006637]; cholesterol homeostasis [GO:0042632]; fatty acid biosynthetic process [GO:0006633]; regulation of blood pressure [GO:0008217] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; butyrate-CoA ligase activity [GO:0047760]; fatty acid ligase activity [GO:0015645]; fatty-acyl-CoA synthase activity [GO:0004321]; metal ion binding [GO:0046872]; methylbutanoate-CoA ligase activity [GO:0043759]; propionate CoA-transferase activity [GO:0018729]; propionate-CoA ligase activity [GO:0050218] 0.94699 -1.3571 LAIFGSVRALHKDNR 0 0 0 0 0 0 11.9618 0 12.1617 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q53G44 IF44L_HUMAN Interferon-induced protein 44-like IFI44L C1orf29 GS3686 Homo sapiens (Human) defense response to virus [GO:0051607]; immune response [GO:0006955] cytoplasm [GO:0005737] GTP binding [GO:0005525] 0.95344 -1.4966 GCMPDRYQFNSR 0 0 0 0 0 0 0 0 0 0 0 0 9.80195 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q53GI3 ZN394_HUMAN Zinc finger protein 394 (Zinc finger protein with KRAB and SCAN domains 14) ZNF394 ZKSCAN14 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96874 -3.32 DAAPSQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.64865 0 0 0 0 0 Q53GL7 PAR10_HUMAN Protein mono-ADP-ribosyltransferase PARP10 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 10) (ARTD10) (Poly [ADP-ribose] polymerase 10) (PARP-10) PARP10 Homo sapiens (Human) chromatin organization [GO:0006325]; NAD biosynthesis via nicotinamide riboside salvage pathway [GO:0034356]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of gene expression [GO:0010629]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein K63-linked ubiquitination [GO:1900045]; protein auto-ADP-ribosylation [GO:0070213]; protein poly-ADP-ribosylation [GO:0070212]; translesion synthesis [GO:0019985]; viral protein processing [GO:0019082] cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleolus [GO:0005730]; nucleus [GO:0005634] DNA-binding transcription factor binding [GO:0140297]; K63-linked polyubiquitin modification-dependent protein binding [GO:0070530]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+- protein-lysine ADP-ribosyltransferase activity [GO:0140804]; NAD+-protein ADP-ribosyltransferase activity [GO:1990404]; nucleotidyltransferase activity [GO:0016779]; transcription corepressor activity [GO:0003714] 0.86958 0.041011 VAMAEAEAGVAVEVR 10.8483 0 0 0 0 0 0 0 0 0 0 10.2125 0 0 0 0 0 0 0 9.52797 0 0 0 0 0 0 0 Q53GQ0 DHB12_HUMAN Very-long-chain 3-oxoacyl-CoA reductase (EC 1.1.1.330) (17-beta-hydroxysteroid dehydrogenase 12) (17-beta-HSD 12) (3-ketoacyl-CoA reductase) (KAR) (Estradiol 17-beta-dehydrogenase 12) (EC 1.1.1.62) (Short chain dehydrogenase/reductase family 12C member 1) HSD17B12 SDR12C1 Homo sapiens (Human) estrogen biosynthetic process [GO:0006703]; extracellular matrix organization [GO:0030198]; fatty acid biosynthetic process [GO:0006633]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; positive regulation of cell-substrate adhesion [GO:0010811] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular matrix [GO:0031012]; fatty acid elongase complex [GO:0009923] 17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; 3-oxo-arachidoyl-CoA reductase activity [GO:0102339]; 3-oxo-behenoyl-CoA reductase activity [GO:0102340]; 3-oxo-cerotoyl-CoA reductase activity [GO:0102342]; 3-oxo-lignoceroyl-CoA reductase activity [GO:0102341]; collagen binding [GO:0005518]; estradiol 17-beta-dehydrogenase [NAD(P)] activity [GO:0004303]; fibronectin binding [GO:0001968]; heparin binding [GO:0008201]; long-chain-3-hydroxyacyl-CoA dehydrogenase activity [GO:0016509]; long-chain-fatty-acyl-CoA reductase activity [GO:0050062]; oxidoreductase activity [GO:0016491] 0.56055 0.53262 IVMNMNK 0 0 0 0 0 0 0 0 0 0 9.43731 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q53GS7 GLE1_HUMAN mRNA export factor GLE1 (hGLE1) (GLE1 RNA export mediator) (GLE1-like protein) (Nucleoporin GLE1) GLE1 GLE1L Homo sapiens (Human) mRNA export from nucleus [GO:0006406]; nucleocytoplasmic transport [GO:0006913]; poly(A)+ mRNA export from nucleus [GO:0016973]; protein transport [GO:0015031] centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear pore cytoplasmic filaments [GO:0044614]; nucleolus [GO:0005730] identical protein binding [GO:0042802]; inositol hexakisphosphate binding [GO:0000822]; phospholipid binding [GO:0005543]; translation initiation factor binding [GO:0031369] 0.96908 -4.1874 DSQAKKIK 0 0 0 0 0 0 0 0 0 10.9126 0 0 9.94867 0 0 0 10.0753 0 0 0 0 0 0 0 0 0 0 Q53H12 AGK_HUMAN "Acylglycerol kinase, mitochondrial (hAGK) (EC 2.7.1.107) (EC 2.7.1.138) (EC 2.7.1.94) (Multiple substrate lipid kinase) (HsMuLK) (MuLK) (Multi-substrate lipid kinase)" AGK MULK Homo sapiens (Human) ceramide biosynthetic process [GO:0046513]; glycerolipid metabolic process [GO:0046486]; protein insertion into mitochondrial inner membrane [GO:0045039] cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial membrane [GO:0031966]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; TIM22 mitochondrial import inner membrane insertion complex [GO:0042721] acylglycerol kinase activity [GO:0047620]; ATP binding [GO:0005524]; ceramide kinase activity [GO:0001729]; diacylglycerol kinase activity [GO:0004143]; dihydroceramide kinase activity [GO:0102773] 0.84875 0.15702 HCDNLLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.39583 0 0 0 0 0 0 0 0 0 0 0 Q53H47 SETMR_HUMAN Histone-lysine N-methyltransferase SETMAR (SET domain and mariner transposase fusion protein) (Metnase) [Includes: Histone-lysine N-methyltransferase (EC 2.1.1.357); Transposon Hsmar1 transposase (EC 3.1.-.-)] SETMAR Homo sapiens (Human) cell population proliferation [GO:0008283]; DNA catabolic process [GO:0006308]; DNA double-strand break processing [GO:0000729]; DNA integration [GO:0015074]; double-strand break repair via nonhomologous end joining [GO:0006303]; histone lysine methylation [GO:0034968]; mitotic DNA integrity checkpoint signaling [GO:0044774]; negative regulation of chromosome organization [GO:2001251]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity [GO:2000373]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; replication fork processing [GO:0031297] nucleolus [GO:0005730]; nucleus [GO:0005634]; site of double-strand break [GO:0035861] DNA binding [GO:0003677]; DNA topoisomerase binding [GO:0044547]; double-stranded DNA binding [GO:0003690]; endonuclease activity [GO:0004519]; histone H3K36 dimethyltransferase activity [GO:0140954]; histone H3K36 methyltransferase activity [GO:0046975]; histone H3K4 methyltransferase activity [GO:0042800]; protein homodimerization activity [GO:0042803]; single-stranded DNA binding [GO:0003697]; single-stranded DNA endodeoxyribonuclease activity [GO:0000014]; zinc ion binding [GO:0008270] 0.9588 -1.8656 DIGSGGK 0 0 0 0 0 0 11.0885 14.3154 0 0 0 9.83543 0 0 0 0 0 0 0 0 9.08813 8.82598 9.33559 8.84037 9.88655 0 9.38193 Q53H54 TYW2_HUMAN tRNA wybutosine-synthesizing protein 2 homolog (tRNA-yW-synthesizing protein 2) (EC 2.5.1.114) (tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase) TRMT12 TRM12 TYW2 Homo sapiens (Human) tRNA methylation [GO:0030488]; wybutosine biosynthetic process [GO:0031591] cytoplasm [GO:0005737] tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity [GO:0102522]; tRNA methyltransferase activity [GO:0008175] 0.79393 0.24483 AQGCSPAQK 0 0 0 0 8.09344 0 0 0 0 0 0 8.97367 0 0 0 0 0 0 0 0 0 0 0 9.64643 0 0 0 Q53H76 PLA1A_HUMAN Phospholipase A1 member A (EC 3.1.1.111) (Phosphatidylserine-specific phospholipase A1) (PS-PLA1) PLA1A NMD PSPLA1 Homo sapiens (Human) lipid catabolic process [GO:0016042]; lipid metabolic process [GO:0006629]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phosphatidylserine metabolic process [GO:0006658] acrosomal membrane [GO:0002080]; extracellular region [GO:0005576]; extracellular space [GO:0005615] lipase activity [GO:0016298]; phosphatidylserine 1-acylhydrolase activity [GO:0052739]; phospholipase A1 activity [GO:0008970] 0.93585 -1.2918 FCTALLPVNDR 0 0 0 0 0 0 0 0 11.3037 0 0 0 0 0 0 0 0 0 0 0 0 10.8258 0 0 0 0 0 Q53H80 AKIR2_HUMAN Akirin-2 AKIRIN2 C6orf166 Homo sapiens (Human) adaptive immune response [GO:0002250]; cerebral cortex development [GO:0021987]; defense response to bacterium [GO:0042742]; embryo development ending in birth or egg hatching [GO:0009792]; innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear protein quality control by the ubiquitin-proteasome system [GO:0071630]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of B cell activation [GO:0050871]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endopeptidase activity [GO:0010950]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome localization [GO:0031144]; protein import into nucleus [GO:0006606]; regulation of muscle cell differentiation [GO:0051147]; response to lipopolysaccharide [GO:0032496] chromatin [GO:0000785]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription repressor complex [GO:0017053] enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; molecular function activator activity [GO:0140677]; protein-macromolecule adaptor activity [GO:0030674]; transcription coregulator activity [GO:0003712] 0.14286 1.0267 QVGMICERLLK 0 10.6803 0 0 0 11.3216 0 0 9.48806 13.2084 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q53H82 LACB2_HUMAN Endoribonuclease LACTB2 (EC 3.1.27.-) (Beta-lactamase-like protein 2) LACTB2 CGI-83 Homo sapiens (Human) "RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]" mitochondrial matrix [GO:0005759] RNA endonuclease activity [GO:0004521]; single-stranded RNA binding [GO:0003727]; zinc ion binding [GO:0008270] 0.63193 0.39921 MAAVLQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.1875 0 0 0 0 0 0 0 0 0 0 0 Q53HC5 KLH26_HUMAN Kelch-like protein 26 KLHL26 Homo sapiens (Human) 0.86321 0.088075 AAVRWLQHDPAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.4261 0 0 0 Q53HI1 UNC50_HUMAN Protein unc-50 homolog (Periodontal ligament-specific protein 22) (PDLs22) (Protein GMH1 homolog) (hGMH1) (Uncoordinated-like protein) UNC50 UNCL HSD-23 HSD23 Homo sapiens (Human) protein localization to cell surface [GO:0034394] Golgi membrane [GO:0000139]; nuclear inner membrane [GO:0005637] RNA binding [GO:0003723] 0.88227 -0.035312 QMDFEFAAWQMLYLFTSPQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5436 0 0 0 0 Q53QW1 TEX44_HUMAN Testis-expressed protein 44 TEX44 C2orf57 Homo sapiens (Human) cytoplasm [GO:0005737] 0.95197 -1.4264 SAEEKAEHPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.35493 0 0 0 0 Q53QZ3 RHG15_HUMAN Rho GTPase-activating protein 15 (ArhGAP15) (Rho-type GTPase-activating protein 15) ARHGAP15 BM-024 BM-030 BM-046 Homo sapiens (Human) regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020] GTPase activator activity [GO:0005096] 0.91563 -0.76876 IEFYKESK 0 0 0 0 0 0 8.82518 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q53R41 FAKD1_HUMAN "FAST kinase domain-containing protein 1, mitochondrial" FASTKD1 KIAA1800 Homo sapiens (Human) mitochondrial RNA metabolic process [GO:0000959]; mitochondrial RNA processing [GO:0000963]; regulation of mitochondrial mRNA stability [GO:0044528] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ribonucleoprotein granule [GO:0035770] RNA binding [GO:0003723] 0.96058 -1.8028 GIGGMDGTQQQIFK 0 0 0 0 0 0 11.8632 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.79219 10.9893 0 0 10.4723 Q53RT3 APRV1_HUMAN Retroviral-like aspartic protease 1 (EC 3.4.23.-) (Skin-specific retroviral-like aspartic protease) (SASPase) (Skin aspartic protease) (TPA-inducible aspartic proteinase-like protein) (TAPS) ASPRV1 SASP Homo sapiens (Human) protein processing [GO:0016485]; skin development [GO:0043588] membrane [GO:0016020] aspartic-type endopeptidase activity [GO:0004190] 0.82997 0.20794 EIVFANSMGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.26887 0 0 0 0 0 Q53RY4 KCP3_HUMAN Keratinocyte-associated protein 3 (KCP-3) KRTCAP3 KCP3 UNQ3066/PRO9898 Homo sapiens (Human) membrane [GO:0016020] 0.87285 0.035204 DGLQGQLEEMTELESPK 0 0 0 0 0 0 0 0 9.81372 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q53S58 TM177_HUMAN Transmembrane protein 177 TMEM177 Homo sapiens (Human) mitochondrial inner membrane [GO:0005743] 0.96206 -2.5603 ASLTLSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.75704 0 0 0 0 0 0 0 0 0 Q53SF7 COBL1_HUMAN Cordon-bleu protein-like 1 COBLL1 KIAA0977 Homo sapiens (Human) extracellular exosome [GO:0070062] actin monomer binding [GO:0003785]; cadherin binding [GO:0045296] 0.9699 -5.2981 DDQDMHALGKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.96112 0 0 9.313 0 10.0206 0 Q53T94 TAF1B_HUMAN TATA box-binding protein-associated factor RNA polymerase I subunit B (RNA polymerase I-specific TBP-associated factor 63 kDa) (TAFI63) (TATA box-binding protein-associated factor 1B) (TBP-associated factor 1B) (Transcription initiation factor SL1/TIF-IB subunit B) TAF1B Homo sapiens (Human) DNA-templated transcription [GO:0006351]; nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase I preinitiation complex assembly [GO:0001188] nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I core factor complex [GO:0070860]; RNA polymerase transcription factor SL1 complex [GO:0005668] metal ion binding [GO:0046872]; RNA polymerase I core promoter sequence-specific DNA binding [GO:0001164]; TBP-class protein binding [GO:0017025] 0.93031 -1.2383 QKWEEARAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1762 0 0 Q53TN4 CYBR1_HUMAN Plasma membrane ascorbate-dependent reductase CYBRD1 (EC 7.2.1.3) (Cytochrome b reductase 1) (Duodenal cytochrome b) (Ferric-chelate reductase 3) CYBRD1 DCYTB FRRS3 Homo sapiens (Human) ascorbate homeostasis [GO:0140576]; intracellular iron ion homeostasis [GO:0006879]; multicellular organismal-level iron ion homeostasis [GO:0060586]; reductive iron assimilation [GO:0033215]; response to iron ion [GO:0010039] apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; extracellular exosome [GO:0070062]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886] "identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on metal ions [GO:0016722]; transmembrane ascorbate ferrireductase activity [GO:0140571]; transmembrane monodehydroascorbate reductase activity [GO:0140575]" 0.76722 0.27839 NLALDEAGQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1538 0 Q53TQ3 IN80D_HUMAN INO80 complex subunit D INO80D Homo sapiens (Human) chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of telomere maintenance in response to DNA damage [GO:1904507]; regulation of cell cycle [GO:0051726]; regulation of chromosome organization [GO:0033044]; regulation of DNA repair [GO:0006282]; regulation of DNA replication [GO:0006275]; regulation of DNA strand elongation [GO:0060382]; regulation of embryonic development [GO:0045995]; telomere maintenance [GO:0000723] Ino80 complex [GO:0031011]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.96126 -2.5629 EPECTGQLIQELR 0 0 0 11.3265 9.509 9.42893 9.41037 0 10.2264 0 0 0 0 9.21917 0 0 10.092 0 0 0 0 0 0 0 0 10.2866 0 Q53TS8 CTSRT_HUMAN Cation channel sperm-associated targeting subunit tau (CatSper-tau) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein) (C2 calcium-dependent domain-containing protein 6) C2CD6 ALS2CR11 CATSPERT Homo sapiens (Human) flagellated sperm motility [GO:0030317]; sperm capacitation [GO:0048240]; spermatogenesis [GO:0007283]; vesicle-mediated transport to the plasma membrane [GO:0098876] CatSper complex [GO:0036128]; sperm principal piece [GO:0097228] 0.96951 -3.5315 DDCHFVEKHSEK 9.04718 0 0 0 0 0 8.5865 0 0 0 0 0 0 0 0 0 0 0 0 0 8.84734 0 0 0 0 0 0 Q562E7 WDR81_HUMAN WD repeat-containing protein 81 WDR81 Homo sapiens (Human) aggrephagy [GO:0035973]; early endosome to late endosome transport [GO:0045022]; mitochondrion organization [GO:0007005]; protein stabilization [GO:0050821]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; ubiquitin-dependent protein catabolic process [GO:0006511] autophagosome membrane [GO:0000421]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; extrinsic component of endosome membrane [GO:0031313]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; mitochondrion [GO:0005739] K63-linked polyubiquitin modification-dependent protein binding [GO:0070530]; phosphatidylinositol 3-kinase regulator activity [GO:0035014] 0.9678 -3.6716 ALLESREVSR 0 0 0 8.11093 0 0 9.32964 0 0 0 0 0 9.27708 0 0 0 10.1204 0 10.1387 0 10.5362 0 0 0 10.227 0 0 Q562F6 SGO2_HUMAN Shugoshin 2 (Shugoshin-2) (Shugoshin-like 2) (Tripin) SGO2 SGOL2 Homo sapiens (Human) cell division [GO:0051301]; chromosome segregation [GO:0007059]; meiotic cell cycle [GO:0051321]; meiotic sister chromatid cohesion [GO:0051177] "chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; kinetochore [GO:0000776]; mitotic cohesin complex [GO:0030892]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]" 0.87759 -0.0053815 DLPFVEEIK 8.71084 0 0 0 0 0 0 0 10.8881 0 0 0 9.02004 0 9.19729 0 0 0 0 0 0 0 0 0 0 0 0 Q562R1 ACTBL_HUMAN Beta-actin-like protein 2 (Kappa-actin) ACTBL2 Homo sapiens (Human) cell motility [GO:0048870] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; NuA4 histone acetyltransferase complex [GO:0035267] ATP binding [GO:0005524]; protein kinase binding [GO:0019901]; structural constituent of postsynaptic actin cytoskeleton [GO:0098973] 0.02069 1.6259 DLTDYLMK 9.51783 9.63052 0 12.1015 12.2684 0 0 14.0586 0 0 0 14.2021 0 14.0689 14.2248 14.4547 14.4265 0 14.9593 14.8544 14.8335 14.4261 14.3602 14.3538 15.838 15.6429 15.4803 Q569H4 LARGN_HUMAN Protein Largen (Mesenchymal stem cell protein DSC54) (Proline-rich protein 16) PRR16 Homo sapiens (Human) positive regulation of cell size [GO:0045793]; positive regulation of translation [GO:0045727] 0.93218 -1.2663 LTPVKCEDPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.38657 Q569K6 CC157_HUMAN Coiled-coil domain-containing protein 157 CCDC157 KIAA1656 Homo sapiens (Human) 0.92133 -1.0934 AGPVRFPSWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5221 0 0 0 0 9.30665 0 Q56P03 EAPP_HUMAN E2F-associated phosphoprotein (EAPP) EAPP C14orf11 BM-036 Homo sapiens (Human) negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968] cytoplasm [GO:0005737]; nucleus [GO:0005634] 0.63201 0.40621 VATAPTR 0 0 0 0 0 0 0 0 0 0 0 0 9.11437 0 0 0 0 10.5113 0 0 0 0 0 0 0 0 0 Q56UN5 M3K19_HUMAN "Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in COPD, protein kinase) (SPS1/STE20-related protein kinase YSK4)" MAP3K19 RCK YSK4 Homo sapiens (Human) protein phosphorylation [GO:0006468] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96955 -5.6009 EDAPHFLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.39506 0 0 0 0 0 Q56VL3 OCAD2_HUMAN OCIA domain-containing protein 2 (Ovarian carcinoma immunoreactive antigen-like protein) OCIAD2 Homo sapiens (Human) endocytosis [GO:0006897]; hematopoietic stem cell homeostasis [GO:0061484]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; response to bacterium [GO:0009617] endosome [GO:0005768]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764] 0.67152 0.39376 GDSQPSAS 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.34833 0 0 0 0 0 0 0 0 0 0 0 Q587I9 SFT2C_HUMAN Vesicle transport protein SFT2C (SFT2 domain-containing protein 3) SFT2D3 Homo sapiens (Human) protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] membrane [GO:0016020] 0.81991 0.21881 QLQEYLAQGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1922 0 0 0 0 0 Q587J7 TDR12_HUMAN Putative ATP-dependent RNA helicase TDRD12 (EC 3.6.4.13) (ES cell-associated transcript 8 protein) (Tudor domain-containing protein 12) TDRD12 ECAT8 Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; fertilization [GO:0009566]; germ-line stem cell division [GO:0042078]; male meiotic nuclear division [GO:0007140]; piRNA processing [GO:0034587]; retrotransposon silencing [GO:0010526]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] PET complex [GO:1990923] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; nucleic acid binding [GO:0003676]; RNA helicase activity [GO:0003724] 0.96208 -2.5603 SAPSFNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.88573 0 0 0 0 0 0 0 0 0 Q587J8 KHDC3_HUMAN KH domain-containing protein 3 (ES cell-associated transcript 1 protein) (KHDC3-like protein) KHDC3L C6orf221 ECAT1 Homo sapiens (Human) actin filament organization [GO:0007015]; establishment of organelle localization [GO:0051656]; negative regulation of apoptotic process [GO:0043066]; positive regulation of dendrite development [GO:1900006]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of embryonic development [GO:0040019]; positive regulation of neurogenesis [GO:0050769]; regulation of protein localization [GO:0032880]; replication fork processing [GO:0031297] cell cortex [GO:0005938]; centrosome [GO:0005813]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; subcortical maternal complex [GO:0106333] RNA binding [GO:0003723] 0.7696 0.26893 RFSWFHSEFLK 0 0 0 0 0 0 0 0 0 0 0 0 9.3853 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q58A45 PAN3_HUMAN PAN2-PAN3 deadenylation complex subunit PAN3 (PAB1P-dependent poly(A)-specific ribonuclease) (Poly(A)-nuclease deadenylation complex subunit 3) (PAN deadenylation complex subunit 3) PAN3 Homo sapiens (Human) "mRNA processing [GO:0006397]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; protein phosphorylation [GO:0006468]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]" cytosol [GO:0005829]; P-body [GO:0000932]; PAN complex [GO:0031251] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; poly(A) binding [GO:0008143]; protein kinase activity [GO:0004672] 0.87107 0.062526 LVPMGSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.12267 0 0 0 0 Q58DX5 NADL2_HUMAN Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2 (NAALADase L2) NAALADL2 Homo sapiens (Human) response to bacterium [GO:0009617] membrane [GO:0016020]; nucleoplasm [GO:0005654] 0.57535 0.4787 KDSSQDLLYSYAAYSAK 0 0 0 0 0 0 0 0 0 0 0 8.78506 0 0 0 0 0 0 0 0 0 0 0 0 10.0968 0 0 Q58EX2 SDK2_HUMAN Protein sidekick-2 SDK2 KIAA1514 Homo sapiens (Human) camera-type eye photoreceptor cell differentiation [GO:0060219]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] plasma membrane [GO:0005886]; synapse [GO:0045202] 0.88392 -0.27987 MWGLLIWTLLALHQIRAAR 0 0 0 0 0 0 0 0 10.6595 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q58F21 BRDT_HUMAN Bromodomain testis-specific protein (Cancer/testis antigen 9) (CT9) (RING3-like protein) BRDT Homo sapiens (Human) chromatin remodeling [GO:0006338]; male meiosis I [GO:0007141]; male meiotic nuclear division [GO:0007140]; mRNA processing [GO:0006397]; positive regulation of transcription involved in meiotic cell cycle [GO:0051039]; regulation of DNA-templated transcription [GO:0006355]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]; sperm DNA condensation [GO:0035092] nucleus [GO:0005634] histone binding [GO:0042393]; histone reader activity [GO:0140566]; lysine-acetylated histone binding [GO:0070577]; transcription coactivator activity [GO:0003713] 0.95161 -1.423 DIKIKNADSWK 14.0551 13.8785 14.2036 0 9.54661 0 11.3856 0 0 0 12.2688 0 9.45886 0 11.943 0 10.8404 0 0 0 0 0 0 0 0 0 0 Q58FF3 ENPLL_HUMAN Putative endoplasmin-like protein (Putative heat shock protein 90 kDa beta member 2) HSP90B2P GRP94B GRP94P1 TRAP1 Homo sapiens (Human) protein folding [GO:0006457] mitochondrial inner membrane [GO:0005743] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; protein kinase binding [GO:0019901]; unfolded protein binding [GO:0051082] 0.96064 -2.0127 ESTAEKDEL 9.86281 0 0 0 9.04851 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q58FF6 H90B4_HUMAN Putative heat shock protein HSP 90-beta 4 HSP90AB4P Homo sapiens (Human) cellular response to heat [GO:0034605]; protein folding [GO:0006457]; protein stabilization [GO:0050821] cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; unfolded protein binding [GO:0051082] 0.9691 -3.4766 EDQTEYLEER 0 0 0 0 0 10.147 0 9.60765 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q58FF7 H90B3_HUMAN Putative heat shock protein HSP 90-beta-3 (Heat shock protein 90-beta c) (Heat shock protein 90Bc) HSP90AB3P HSP90BC Homo sapiens (Human) cellular response to heat [GO:0034605]; protein folding [GO:0006457]; protein stabilization [GO:0050821] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; unfolded protein binding [GO:0051082] 0.96781 -2.964 ADLINNLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.71864 8.43696 0 0 0 0 0 0 0 Q58FG0 HS905_HUMAN Putative heat shock protein HSP 90-alpha A5 (Heat shock protein 90-alpha E) (Heat shock protein 90Ae) HSP90AA5P HSP90AE Homo sapiens (Human) cytoplasm [GO:0005737] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; unfolded protein binding [GO:0051082] 0.96446 -2.3831 DQVANSAFVECLQK 0 0 0 0 0 0 8.91013 0 0 0 13.6306 0 8.76716 0 0 0 0 0 0 0 0 0 0 10.0204 0 0 0 Q58G82 SY14L_HUMAN Putative synaptotagmin-14-like protein (Synaptotagmin XIV protein pseudogene 1) (Synaptotagmin XIV-derived protein) (Synaptotagmin XIV-like protein) SYT14P1 SYT14L SYT14LP1 SYTDEP Homo sapiens (Human) cell differentiation [GO:0030154]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of dendrite extension [GO:1903861]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] phospholipid binding [GO:0005543] 0.96284 -2.6704 LSAEVIKGSHLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.582 Q58WW2 DCAF6_HUMAN DDB1- and CUL4-associated factor 6 (Androgen receptor complex-associated protein) (ARCAP) (IQ motif and WD repeat-containing protein 1) (Nuclear receptor interaction protein) (NRIP) DCAF6 IQWD1 MSTP055 Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944]; protein ubiquitination [GO:0016567] Cul4-RING E3 ubiquitin ligase complex [GO:0080008]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] nuclear receptor coactivator activity [GO:0030374] 0.88417 -0.15047 SEGSGQENENEDEE 0 9.24296 0 0 0 0 0 0 0 9.34731 9.28251 9.09706 0 0 0 0 0 9.01436 0 0 0 0 0 0 0 0 0 Q59EK9 RUN3A_HUMAN RUN domain-containing protein 3A (Rap2-interacting protein 8) (RPIP-8) RUNDC3A RAP2IP RPIP8 Homo sapiens (Human) positive regulation of cGMP-mediated signaling [GO:0010753]; small GTPase mediated signal transduction [GO:0007264] cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886] GTPase regulator activity [GO:0030695] 0.96083 -2.0123 MEQKFRIVYAQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.8489 0 Q59H18 TNI3K_HUMAN Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac troponin I-interacting kinase) (TNNI3-interacting kinase) TNNI3K CARK Homo sapiens (Human) bundle of His cell to Purkinje myocyte communication [GO:0086069]; protein phosphorylation [GO:0006468]; regulation of cardiac conduction [GO:1903779]; regulation of cardiac muscle contraction [GO:0055117]; regulation of heart rate [GO:0002027] cytoplasm [GO:0005737]; nucleus [GO:0005634] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.89867 -0.57925 LEDDLQIK 0 0 0 0 0 0 0 9.47703 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5BJE1 CC178_HUMAN Coiled-coil domain-containing protein 178 CCDC178 C18orf34 Homo sapiens (Human) ciliary basal body [GO:0036064] 0.9659 -2.3009 EEEVTEAIRETK 0 0 0 0 0 0 12.8473 0 13.2356 0 0 0 0 0 0 0 9.05561 8.86771 0 0 0 0 0 9.4079 0 10.5198 0 Q5BJF2 SGMR2_HUMAN Sigma intracellular receptor 2 (Sigma-2 receptor) (Sigma2 receptor) (Meningioma-associated protein 30) (Transmembrane protein 97) TMEM97 MAC30 S2R Homo sapiens (Human) cholesterol homeostasis [GO:0042632]; regulation of cell growth [GO:0001558] endoplasmic reticulum [GO:0005783]; lysosome [GO:0005764]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; rough endoplasmic reticulum membrane [GO:0030867] 0.92231 -1.1212 NLLKWYAKEFK 14.4149 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5BJF6 ODFP2_HUMAN Outer dense fiber protein 2 (Cenexin) (Outer dense fiber of sperm tails protein 2) ODF2 Homo sapiens (Human) cell differentiation [GO:0030154]; centriole-centriole cohesion [GO:0010457]; cilium organization [GO:0044782]; protein localization [GO:0008104]; regulation of cilium assembly [GO:1902017]; spermatogenesis [GO:0007283] centriolar subdistal appendage [GO:0120103]; centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cilium [GO:0005929]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; nucleus [GO:0005634]; sperm flagellum [GO:0036126]; spindle pole [GO:0000922] small GTPase binding [GO:0031267]; structural molecule activity [GO:0005198] 0.92188 -1.1111 AIRAQKER 0 0 0 9.19059 0 0 0 8.99356 0 9.71205 10.5354 9.84057 0 0 9.70042 0 10.2789 0 0 0 0 0 0 0 0 0 0 Q5BJH2 TM128_HUMAN Transmembrane protein 128 TMEM128 Homo sapiens (Human) membrane [GO:0016020] 0.93237 -1.2865 DSSRARQQLR 0 0 0 0 8.79675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5BKX5 ACTMP_HUMAN Actin maturation protease (EC 3.4.11.-) (Actin aminopeptidase ACTMAP) ACTMAP C19orf54 Homo sapiens (Human) protein initiator methionine removal involved in protein maturation [GO:0035551] cytoplasm [GO:0005737] cysteine-type aminopeptidase activity [GO:0070005] 0.87773 0.021047 LAQEVLGCQAK 0 0 0 0 0 0 0 0 0 0 0 10.4865 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5BKZ1 ZN326_HUMAN DBIRD complex subunit ZNF326 (Zinc finger protein 326) (Zinc finger protein interacting with mRNPs and DBC1) ZNF326 ZIRD Homo sapiens (Human) mRNA processing [GO:0006397]; regulation of DNA-templated transcription elongation [GO:0032784]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] DBIRD complex [GO:0044609]; intracellular membrane-bounded organelle [GO:0043231]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA polymerase II complex binding [GO:0000993] 0.94914 -1.3777 DFEDDYTHSACR 10.3529 0 0 0 0 0 0 0 0 0 9.07023 9.22106 8.69561 0 0 10.405 0 9.33063 0 0 0 10.0432 0 0 0 0 0 Q5C9Z4 NOM1_HUMAN Nucleolar MIF4G domain-containing protein 1 (SGD1 homolog) NOM1 C7orf3 Homo sapiens (Human) hair follicle maturation [GO:0048820]; ribosomal small subunit biogenesis [GO:0042274] nucleolus [GO:0005730] RNA binding [GO:0003723] 0.93713 -1.2926 KFDAIYKYGSEGK 0 0 0 0 0 0 0 9.34027 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5CZ79 AN20B_HUMAN Ankyrin repeat domain-containing protein 20B (Ankyrin repeat domain-containing protein 20A pseudogene) ANKRD20A8P ANKRD20B Homo sapiens (Human) 0.96705 -2.8387 AEGVVSIKEDKYFQTSR 0 0 0 11.1365 8.92354 8.7003 9.66012 0 0 0 0 0 10.0982 0 0 0 10.4339 0 9.97957 9.84475 0 0 0 0 0 0 0 Q5CZA5 ZN805_HUMAN Zinc finger protein 805 ZNF805 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.61327 0.42305 ECGKAFSNRADLIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.12063 0 0 0 0 0 Q5CZC0 FSIP2_HUMAN Fibrous sheath-interacting protein 2 FSIP2 Homo sapiens (Human) flagellated sperm motility [GO:0030317]; protein localization to cilium [GO:0061512]; sperm axoneme assembly [GO:0007288] sperm connecting piece [GO:0097224]; sperm end piece [GO:0097229]; sperm midpiece [GO:0097225]; sperm principal piece [GO:0097228] 0.96833 -9.2248 DLIQMVLNK 0 12.6984 0 0 0 9.65152 0 10.1536 0 0 8.8282 10.3378 10.6837 12.0508 9.38409 10.9821 0 0 9.95187 9.39397 0 9.58404 9.81189 9.63963 11.0782 0 0 Q5D0E6 DALD3_HUMAN DALR anticodon-binding domain-containing protein 3 DALRD3 Homo sapiens (Human) arginyl-tRNA aminoacylation [GO:0006420]; tRNA C3-cytosine methylation [GO:0106217] arginine-tRNA ligase activity [GO:0004814]; ATP binding [GO:0005524]; tRNA binding [GO:0000049] 0.78894 0.25147 LDLLWQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.84991 Q5D1E8 ZC12A_HUMAN Endoribonuclease ZC3H12A (EC 3.1.-.-) (Monocyte chemotactic protein-induced protein 1) (MCP-induced protein 1) (MCPIP-1) (Regnase-1) (Reg1) (Zinc finger CCCH domain-containing protein 12A) ZC3H12A MCPIP MCPIP1 Homo sapiens (Human) "3'-UTR-mediated mRNA destabilization [GO:0061158]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cellular response to chemokine [GO:1990869]; cellular response to glucose starvation [GO:0042149]; cellular response to interleukin-1 [GO:0071347]; cellular response to ionomycin [GO:1904637]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cellular response to sodium arsenite [GO:1903936]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; DNA damage response [GO:0006974]; immune response-activating signaling pathway [GO:0002757]; inflammatory response [GO:0006954]; miRNA catabolic process [GO:0010587]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of gene expression [GO:0010629]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of macrophage activation [GO:0043031]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T-helper 17 cell differentiation [GO:2000320]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; nervous system development [GO:0007399]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nuclear-transcribed mRNA catabolic process, RNase MRP-dependent [GO:0000294]; positive regulation of angiogenesis [GO:0045766]; positive regulation of autophagy [GO:0010508]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of gene expression [GO:0010628]; positive regulation of lipid storage [GO:0010884]; positive regulation of miRNA catabolic process [GO:2000627]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of protein deubiquitination [GO:1903003]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein complex oligomerization [GO:0051259]; protein deubiquitination [GO:0016579]; regulation of gene expression [GO:0010468]; RNA phosphodiester bond hydrolysis [GO:0090501]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; T cell receptor signaling pathway [GO:0050852]" cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoskeleton [GO:0005856]; extrinsic component of endoplasmic reticulum membrane [GO:0042406]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; protein-containing complex [GO:0032991]; rough endoplasmic reticulum [GO:0005791]; rough endoplasmic reticulum membrane [GO:0030867] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; ribosome binding [GO:0043022]; RNA binding [GO:0003723]; RNA endonuclease activity [GO:0004521]; RNA exonuclease activity [GO:0004532]; RNA nuclease activity [GO:0004540]; RNA stem-loop binding [GO:0035613] 0.82251 0.21714 LGAQASPGSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4941 0 0 0 0 0 0 0 0 0 0 Q5D862 FILA2_HUMAN Filaggrin-2 (FLG-2) (Intermediate filament-associated and psoriasis-susceptibility protein) (Ifapsoriasin) FLG2 IFPS Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis morphogenesis [GO:0048730]; establishment of skin barrier [GO:0061436] cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; keratohyalin granule [GO:0036457]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724] calcium ion binding [GO:0005509]; structural molecule activity [GO:0005198]; transition metal ion binding [GO:0046914] 0.87044 0.054 ENGQPQNCGGQWR 0 0 0 10.7233 0 10.7571 0 14.8446 0 0 0 0 9.80195 0 0 0 0 0 0 0 0 0 0 0 0 9.10079 0 Q5DID0 UROL1_HUMAN Uromodulin-like 1 (Olfactorin) UMODL1 Homo sapiens (Human) adipose tissue development [GO:0060612]; cellular response to gonadotropin-releasing hormone [GO:0097211]; multicellular organismal reproductive process [GO:0048609]; regulation of gene expression [GO:0010468]; regulation of granulosa cell apoptotic process [GO:1904708]; regulation of ovarian follicle development [GO:2000354]; single fertilization [GO:0007338] cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615] calcium ion binding [GO:0005509]; peptidase inhibitor activity [GO:0030414] 0.22911 0.86747 GDTFIQDYDECERK 0 0 0 9.38629 9.20528 9.39184 0 0 0 0 0 0 0 9.61117 0 0 0 0 0 0 0 0 0 0 9.42381 0 0 Q5DX21 IGS11_HUMAN Immunoglobulin superfamily member 11 (IgSF11) (Brain and testis-specific immunoglobulin superfamily protein) (Bt-IGSF) (V-set and immunoglobulin domain-containing protein 3) IGSF11 BTIGSF CXADRL1 VSIG3 Homo sapiens (Human) cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; maintenance of protein location [GO:0045185]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of mini excitatory postsynaptic potential [GO:0061885] cell-cell junction [GO:0005911]; excitatory synapse [GO:0060076]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] ionotropic glutamate receptor binding [GO:0035255] 0.59132 0.46193 LPPTATQDQVQGTVTIR 9.56278 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8333 0 0 0 Q5EBL4 RIPL1_HUMAN RILP-like protein 1 (Rab-interacting lysosomal-like protein 1) RILPL1 RLP1 Homo sapiens (Human) cilium assembly [GO:0060271]; epithelial cell morphogenesis [GO:0003382]; nitric oxide mediated signal transduction [GO:0007263]; protein transport from ciliary membrane to plasma membrane [GO:1903445]; regulation of neuron death [GO:1901214] centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] dynein light intermediate chain binding [GO:0051959]; protein dimerization activity [GO:0046983]; small GTPase binding [GO:0031267] 0.92377 -1.1666 EVVDKQRDEIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4135 0 0 0 0 0 0 10.5886 0 10.4028 Q5EBM0 CMPK2_HUMAN "UMP-CMP kinase 2, mitochondrial (EC 2.7.4.14) (Nucleoside-diphosphate kinase) (EC 2.7.4.6)" CMPK2 Homo sapiens (Human) cellular response to lipopolysaccharide [GO:0071222]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; phosphorylation [GO:0016310] cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] ATP binding [GO:0005524]; CMP kinase activity [GO:0036430]; cytidylate kinase activity [GO:0004127]; dCMP kinase activity [GO:0036431]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; UMP kinase activity [GO:0033862]; uridylate kinase activity [GO:0009041] 0.96931 -3.1369 GVCAGAMAPPR 0 0 0 0 0 0 15.5978 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.13976 0 Q5EBN2 TRI61_HUMAN Putative tripartite motif-containing protein 61 (RING finger protein 35) TRIM61 RNF35 Homo sapiens (Human) protein ubiquitination [GO:0016567] cytoplasm [GO:0005737] ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.94345 -1.3377 VITMQTRKSLELK 0 9.51124 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5FBB7 SGO1_HUMAN Shugoshin 1 (Serologically defined breast cancer antigen NY-BR-85) (Shugoshin-like 1) SGO1 SGOL1 Homo sapiens (Human) "attachment of spindle microtubules to kinetochore [GO:0008608]; cell division [GO:0051301]; centriole-centriole cohesion [GO:0010457]; chromosome segregation [GO:0007059]; meiotic chromosome segregation [GO:0045132]; mitotic sister chromatid cohesion, centromeric [GO:0071962]; mitotic sister chromatid segregation [GO:0000070]" "centrosome [GO:0005813]; chromosome, centromeric region [GO:0000775]; condensed chromosome, centromeric region [GO:0000779]; cytosol [GO:0005829]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; spindle pole [GO:0000922]" kinase binding [GO:0019900] 0.96943 -3.1577 EDILESKSEQTKSK 0 0 0 0 9.23993 0 0 0 0 0 0 0 0 0 0 0 0 0 8.84615 0 8.96645 0 0 0 0 0 0 Q5FWF5 ESCO1_HUMAN N-acetyltransferase ESCO1 (EC 2.3.1.-) (CTF7 homolog 1) (Establishment factor-like protein 1) (EFO1) (EFO1p) (hEFO1) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) ESCO1 EFO1 KIAA1911 Homo sapiens (Human) mitotic sister chromatid cohesion [GO:0007064]; peptidyl-lysine acetylation [GO:0018394]; post-translational protein acetylation [GO:0034421]; regulation of DNA replication [GO:0006275] chromatin [GO:0000785]; chromosome [GO:0005694]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] acetyltransferase activity [GO:0016407]; identical protein binding [GO:0042802]; N-acetyltransferase activity [GO:0008080]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; zinc ion binding [GO:0008270] 0.95145 -1.4407 LDSQVSPK 0 0 0 0 0 8.92585 0 0 0 0 0 0 0 0 0 0 9.96867 0 0 0 0 0 0 0 0 0 0 Q5FWF6 ZN789_HUMAN Zinc finger protein 789 ZNF789 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleoplasm [GO:0005654] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.82891 0.20384 LTFPTSGDEYSR 0 0 0 0 0 0 0 0 0 10.2911 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5FYA8 ARSH_HUMAN Arylsulfatase H (ASH) (EC 3.1.6.-) ARSH Homo sapiens (Human) endoplasmic reticulum lumen [GO:0005788]; membrane [GO:0016020] arylsulfatase activity [GO:0004065]; metal ion binding [GO:0046872] 0.8974 -0.53014 EDDILPMAP 0 0 8.84059 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5GAN4 RNS12_HUMAN Probable inactive ribonuclease-like protein 12 RNASE12 Homo sapiens (Human) defense response to Gram-positive bacterium [GO:0050830] extracellular region [GO:0005576] nucleic acid binding [GO:0003676]; RNA nuclease activity [GO:0004540] 0.80172 0.23934 MTVCQLIEGTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.83202 Q5GAN6 RNS10_HUMAN Inactive ribonuclease-like protein 10 RNASE10 Homo sapiens (Human) defense response to Gram-positive bacterium [GO:0050830]; heterotypic cell-cell adhesion [GO:0034113]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of flagellated sperm motility [GO:1902093]; regulation of fertilization [GO:0080154]; single fertilization [GO:0007338] extracellular region [GO:0005576] nucleic acid binding [GO:0003676] 0.89886 -0.64215 MLRASALFQSNK 0 0 0 0 0 0 0 0 0 13.1631 0 0 11.7794 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5GFL6 VWA2_HUMAN von Willebrand factor A domain-containing protein 2 (A domain-containing protein similar to matrilin and collagen) (AMACO) (Colon cancer secreted protein 2) (CCSP-2) VWA2 AMACO Homo sapiens (Human) calcium-independent cell-matrix adhesion [GO:0007161]; regulation of insulin receptor signaling pathway [GO:0046626] basement membrane [GO:0005604]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615] calcium ion binding [GO:0005509]; identical protein binding [GO:0042802] 0.95758 -1.664 GARPGVPKAVVVLTGGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.76578 0 0 Q5GH72 XKR7_HUMAN XK-related protein 7 XKR7 C20orf159 XRG7 Homo sapiens (Human) apoptotic process involved in development [GO:1902742]; engulfment of apoptotic cell [GO:0043652]; phosphatidylserine exposure on apoptotic cell surface [GO:0070782] plasma membrane [GO:0005886] 0.95487 -1.5072 SLPRTTGAER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4045 0 0 0 0 0 0 0 Q5GH77 XKR3_HUMAN XK-related protein 3 (X Kell blood group-related 3) (XTES) XKR3 XRG3 Homo sapiens (Human) plasma membrane [GO:0005886] 0.9696 -3.5392 CLHTIRNYHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.91097 0 0 0 0 0 12.3721 0 0 Q5GLZ8 HERC4_HUMAN Probable E3 ubiquitin-protein ligase HERC4 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 4) (HECT-type E3 ubiquitin transferase HERC4) HERC4 KIAA1593 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of smoothened signaling pathway [GO:0045879]; protein ubiquitination [GO:0016567]; spermatogenesis [GO:0007283]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737]; cytosol [GO:0005829]; fibrillar center [GO:0001650] ubiquitin protein ligase activity [GO:0061630] 0.88041 -0.030302 EFFLLIMRELLDPK 0 0 0 9.96824 10.851 0 0 0 0 0 0 0 9.99322 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5H8C1 FREM1_HUMAN FRAS1-related extracellular matrix protein 1 (Protein QBRICK) FREM1 C9orf143 C9orf145 C9orf154 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; cell communication [GO:0007154]; cell-matrix adhesion [GO:0007160]; craniofacial suture morphogenesis [GO:0097094] basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; membrane [GO:0016020] carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872] 0.96941 -3.3866 DLFNGIIYYR 0 0 0 0 0 10.8743 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1707 0 Q5H9I0 TFDP3_HUMAN Transcription factor Dp family member 3 (Cancer/testis antigen 30) (CT30) (Hepatocellular carcinoma-associated antigen 661) TFDP3 DP4 HCA661 Homo sapiens (Human) DNA damage response [GO:0006974]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] DNA binding [GO:0003677]; DNA-binding transcription factor binding [GO:0140297]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription regulator inhibitor activity [GO:0140416] 0.92784 -1.2252 KGEKNGMGLCR 0 0 0 0 0 0 0 0 0 9.13227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5H9K5 ZMAT1_HUMAN Zinc finger matrin-type protein 1 ZMAT1 KIAA1789 Homo sapiens (Human) nucleus [GO:0005634] DNA binding [GO:0003677]; zinc ion binding [GO:0008270] 0.49951 0.61418 EVVDSRPR 0 0 0 0 0 0 0 0 0 9.74499 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3519 0 0 Q5H9L4 TAF7L_HUMAN Transcription initiation factor TFIID subunit 7-like (Cancer/testis antigen 40) (CT40) (RNA polymerase II TBP-associated factor subunit Q) (TATA box-binding protein-associated factor 50 kDa) (Transcription initiation factor TFIID 50 kDa subunit) TAF7L TAF2Q Homo sapiens (Human) cell differentiation [GO:0030154]; RNA polymerase II preinitiation complex assembly [GO:0051123]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; transcription factor TFIID complex [GO:0005669] 0.93231 -1.2868 LLRSDAEAVSTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.943 0 0 0 0 0 0 0 0 0 10.1029 0 9.42204 Q5H9M0 PWP3B_HUMAN PWWP domain-containing DNA repair factor 3B (PWWP3B) (Mutated melanoma-associated antigen 1-like protein 1) (MUM1-like protein 1) (PWWP domain-containing protein MUM1L1) PWWP3B MUM1L1 Homo sapiens (Human) extracellular exosome [GO:0070062] 0.96567 -2.7199 EESACVKDEK 0 0 0 11.8042 0 0 0 0 0 0 0 0 9.40689 0 9.21471 10.2936 0 0 9.80658 0 10.1113 0 0 0 0 0 0 Q5H9R4 ARMX4_HUMAN Armadillo repeat-containing X-linked protein 4 ARMCX4 Homo sapiens (Human) membrane [GO:0016020] 0.91817 -0.87026 EQVVGDSRLGLR 0 0 0 0 0 0 0 9.47543 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5H9R7 PP6R3_HUMAN Serine/threonine-protein phosphatase 6 regulatory subunit 3 (SAPS domain family member 3) (Sporulation-induced transcript 4-associated protein SAPL) PPP6R3 C11orf23 KIAA1558 PP6R3 SAPL SAPS3 Homo sapiens (Human) regulation of phosphoprotein phosphatase activity [GO:0043666] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] protein phosphatase binding [GO:0019903]; protein phosphatase regulator activity [GO:0019888] 0.88472 -0.29581 GRLGSFHELLLEPPK 9.03262 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5H9S7 DCA17_HUMAN DDB1- and CUL4-associated factor 17 DCAF17 C2orf37 Homo sapiens (Human) protein ubiquitination [GO:0016567] Cul4-RING E3 ubiquitin ligase complex [GO:0080008]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] 0.96325 -2.1521 ALGCFSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.92346 0 0 0 Q5H9T9 FSCB_HUMAN Fibrous sheath CABYR-binding protein FSCB C14orf155 Homo sapiens (Human) negative regulation of protein sumoylation [GO:0033234] sperm fibrous sheath [GO:0035686]; sperm principal piece [GO:0097228] calcium ion binding [GO:0005509] 0.88386 -0.056157 VASAEIEPPSTEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.05845 0 0 0 0 0 0 0 0 0 Q5H9U9 DDX6L_HUMAN Probable ATP-dependent RNA helicase DDX60-like (EC 3.6.4.13) (DEAD box protein 60-like) DDX60L Homo sapiens (Human) defense response to virus [GO:0051607] cytoplasm [GO:0005737] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; double-stranded RNA binding [GO:0003725]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727] 0.96344 -2.1141 CHVDEQSRDPHVLDFLKK 11.211 0 0 9.16857 0 0 9.72632 9.53461 0 9.00183 10.5605 0 0 0 0 0 11.1237 0 0 10.1579 0 0 0 0 10.8602 0 0 Q5HY98 ZN766_HUMAN Zinc finger protein 766 ZNF766 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.89007 -0.48444 IRTGEKPYKCK 11.595 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4941 0 0 0 10.6392 Q5HYA8 MKS3_HUMAN Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67) TMEM67 MKS3 Homo sapiens (Human) cilium assembly [GO:0060271]; negative regulation of centrosome duplication [GO:0010826]; non-canonical Wnt signaling pathway [GO:0035567]; ubiquitin-dependent ERAD pathway [GO:0030433] centrosome [GO:0005813]; ciliary membrane [GO:0060170]; ciliary transition zone [GO:0035869]; cytoplasmic vesicle membrane [GO:0030659]; endoplasmic reticulum membrane [GO:0005789]; MKS complex [GO:0036038] filamin binding [GO:0031005]; unfolded protein binding [GO:0051082] 0.40632 0.69556 GGAGVAMAVWSLLSAR 9.72787 0 0 9.26329 0 9.1221 0 0 0 0 0 10.0144 0 0 0 0 0 0 0 0 0 0 0 0 10.5438 0 0 Q5HYC2 K2026_HUMAN Uncharacterized protein KIAA2026 KIAA2026 Homo sapiens (Human) 0.72216 0.36081 EGKAVAKEVPPLQQK 0 0 9.11928 0 0 0 8.61574 0 0 0 0 0 0 12.9336 8.72503 0 0 0 0 0 0 11.1883 0 0 0 0 0 Q5HYI7 MTX3_HUMAN Metaxin-3 MTX3 Homo sapiens (Human) inner mitochondrial membrane organization [GO:0007007]; mitochondrion organization [GO:0007005]; protein transport [GO:0015031] cytoplasm [GO:0005737]; MIB complex [GO:0140275]; SAM complex [GO:0001401] 0.91805 -0.87643 EVEAQIYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0101 0 0 0 0 0 0 0 0 Q5HYI8 RABL3_HUMAN Rab-like protein 3 RABL3 Homo sapiens (Human) B cell differentiation [GO:0030183]; intracellular protein transport [GO:0006886]; natural killer cell differentiation [GO:0001779]; protein stabilization [GO:0050821]; regulation of protein lipidation [GO:1903059]; regulation of Ras protein signal transduction [GO:0046578]; T cell differentiation in thymus [GO:0033077] endomembrane system [GO:0012505] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein homodimerization activity [GO:0042803] 0.95024 -1.4091 LDQIHETK 0 0 0 11.0723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.51335 0 0 Q5HYJ1 TECRL_HUMAN "Trans-2,3-enoyl-CoA reductase-like (EC 1.3.1.-) (Steroid 5-alpha-reductase 2-like 2 protein)" TECRL SRD5A2L2 Homo sapiens (Human) very long-chain fatty acid biosynthetic process [GO:0042761] endoplasmic reticulum [GO:0005783]; membrane [GO:0016020] "oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]" 0.59053 0.46373 IPCIYDGK 0 0 0 0 0 0 0 0 0 0 8.71143 0 0 0 0 0 0 9.84541 0 0 0 0 0 0 0 0 0 Q5HYK7 SH319_HUMAN SH3 domain-containing protein 19 (ADAM-binding protein Eve-1) (EEN-binding protein) (EBP) SH3D19 Homo sapiens (Human) cytoskeleton organization [GO:0007010]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; regulation of cell morphogenesis [GO:0022604] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] proline-rich region binding [GO:0070064] 0.84404 0.13836 NLESNHPGQTGGFVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.95603 0 0 0 0 0 0 0 0 Q5HYK9 ZN667_HUMAN Zinc finger protein 667 ZNF667 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96415 -2.1079 IHAGEKIPENAK 0 8.61923 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.66391 0 0 0 0 0 0 Q5HYM0 ZC12B_HUMAN Probable ribonuclease ZC3H12B (EC 3.1.-.-) (MCP-induced protein 2) (Zinc finger CCCH domain-containing protein 12B) ZC3H12B CXorf32 MCPIP2 Homo sapiens (Human) "RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]" cytoplasmic ribonucleoprotein granule [GO:0036464]; nucleus [GO:0005634] metal ion binding [GO:0046872]; mRNA binding [GO:0003729]; RNA endonuclease activity [GO:0004521] 0.9153 -0.81048 KEMHSKPHR 0 0 0 0 0 0 0 0 0 0 9.40941 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5HYW2 NHSL2_HUMAN NHS-like protein 2 NHSL2 Homo sapiens (Human) cell differentiation [GO:0030154] 0.87363 0.024684 TIIGFSNFSQR 0 0 0 0 0 0 0 9.72344 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5HYW3 RTL5_HUMAN Retrotransposon Gag-like protein 5 (Retrotransposon gag domain-containing protein 4) RTL5 KIAA2001 RGAG4 Homo sapiens (Human) 0.96946 -4.0884 EEEEEIRNK 0 11.9743 0 9.43296 0 0 9.12678 11.9234 12.0793 0 0 0 0 0 10.4922 0 11.1449 0 0 0 0 0 0 0 0 0 0 Q5I0G3 MDH1B_HUMAN Putative malate dehydrogenase 1B (EC 1.1.1.-) MDH1B Homo sapiens (Human) malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099] L-malate dehydrogenase activity [GO:0030060] 0.41921 0.67515 GIVFSMPVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3382 0 0 0 0 0 0 0 Q5IJ48 CRUM2_HUMAN Protein crumbs homolog 2 (Crumbs-like protein 2) CRB2 Homo sapiens (Human) circulatory system development [GO:0072359]; establishment of cell polarity [GO:0030010]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; ingression involved in gastrulation with mouth forming second [GO:0055111]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; mesoderm formation [GO:0001707]; negative regulation of endopeptidase activity [GO:0010951]; notochord formation [GO:0014028]; photoreceptor cell maintenance [GO:0045494]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; regulation of gastrulation [GO:0010470]; response to stimulus [GO:0050896]; retina homeostasis [GO:0001895]; retinal cone cell development [GO:0046549]; somitogenesis [GO:0001756]; visual perception [GO:0007601] apical junction complex [GO:0043296]; apical plasma membrane [GO:0016324]; apicolateral plasma membrane [GO:0016327]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; subapical complex [GO:0035003] aspartic-type endopeptidase inhibitor activity [GO:0019828]; calcium ion binding [GO:0005509]; protein-containing complex binding [GO:0044877] 0.92152 -1.1142 CHTHPDGRFECR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.63214 0 0 0 0 Q5JNZ3 ZN311_HUMAN Zinc finger protein 311 (Zinc finger protein zfp-31) ZNF311 ZFP31 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96244 -2.6274 DFSIKAELTK 0 0 0 0 0 0 0 0 0 0 15.9296 9.97599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5JPB2 ZN831_HUMAN Zinc finger protein 831 ZNF831 C20orf174 Homo sapiens (Human) metal ion binding [GO:0046872] 0.95994 -1.7492 AGEPPRPEGR 0 0 8.33972 0 0 0 8.91785 8.84718 9.91358 9.73887 0 9.40776 0 0 0 0 0 0 0 9.95591 0 0 0 0 0 9.47472 0 Q5JPE7 NOMO2_HUMAN BOS complex subunit NOMO2 (Nodal modulator 2) (pM5 protein 2) NOMO2 Homo sapiens (Human) multi-pass transmembrane protein insertion into ER membrane [GO:0160063] endoplasmic reticulum membrane [GO:0005789]; multi-pass translocon complex [GO:0160064]; protein-containing complex [GO:0032991] carbohydrate binding [GO:0030246]; ribosome binding [GO:0043022] 0.56566 0.48491 AKPGTYKVQVMVPEAETR 0 11.8517 0 0 0 0 0 0 0 0 0 0 0 10.4653 0 0 0 0 0 0 0 0 0 0 0 8.78437 10.8059 Q5JPF3 AN36C_HUMAN Ankyrin repeat domain-containing protein 36C (Protein immuno-reactive with anti-PTH polyclonal antibodies) ANKRD36C Homo sapiens (Human) ion channel inhibitor activity [GO:0008200] 0.96939 -4.9668 CELNLCDREDR 0 0 0 0 10.4446 0 0 0 0 0 0 0 0 10.2822 0 10.5583 0 0 8.5343 0 9.64832 8.83235 0 10.2819 0 9.92404 0 Q5JQC9 AKAP4_HUMAN A-kinase anchor protein 4 (AKAP-4) (A-kinase anchor protein 82 kDa) (AKAP 82) (hAKAP82) (Major sperm fibrous sheath protein) (HI) (Protein kinase A-anchoring protein 4) (PRKA4) AKAP4 AKAP82 Homo sapiens (Human) establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; flagellated sperm motility [GO:0030317]; protein localization [GO:0008104]; signal transduction [GO:0007165]; single fertilization [GO:0007338]; sperm flagellum assembly [GO:0120316]; transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178] cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; motile cilium [GO:0031514]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; sperm connecting piece [GO:0097224]; sperm end piece [GO:0097229]; sperm fibrous sheath [GO:0035686]; sperm midpiece [GO:0097225]; sperm principal piece [GO:0097228]; Z disc [GO:0030018] protein kinase A binding [GO:0051018] 0.96181 -2.5574 AGSHDPK 0 0 0 0 0 0 0 0 10.6176 9.43661 9.26618 0 10.0353 0 9.28306 10.41 9.98413 0 0 8.62048 0 9.28887 8.69832 0 0 0 0 Q5JR12 PPM1J_HUMAN Protein phosphatase 1J (EC 3.1.3.16) (Protein phosphatase 2C isoform zeta) (PP2C-zeta) PPM1J PPP2CZ Homo sapiens (Human) positive regulation of pyruvate dehydrogenase activity [GO:1904184]; protein dephosphorylation [GO:0006470] [pyruvate dehydrogenase (lipoamide)] phosphatase activity [GO:0004741]; myosin phosphatase activity [GO:0017018] 0.95225 -1.3876 ADDHAGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.7619 0 0 0 Q5JR59 MTUS2_HUMAN Microtubule-associated tumor suppressor candidate 2 (Cardiac zipper protein) (Microtubule plus-end tracking protein TIP150) (Tracking protein of 150 kDa) MTUS2 CAZIP KIAA0774 TIP150 Homo sapiens (Human) cytoplasm [GO:0005737]; intercellular bridge [GO:0045171]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; nucleus [GO:0005634] microtubule binding [GO:0008017]; protein homodimerization activity [GO:0042803] 0.96373 -2.4059 ASLPSKDTPK 0 0 0 0 0 0 0 9.88044 10.2057 10.1272 0 0 12.6665 0 0 10.2758 0 14.938 9.03089 10.2879 0 10.1218 0 0 0 0 10.4463 Q5JRA6 TGO1_HUMAN Transport and Golgi organization protein 1 homolog (TANGO1) (C219-reactive peptide) (D320) (Melanoma inhibitory activity protein 3) MIA3 KIAA0268 TANGO UNQ6077/PRO20088 Homo sapiens (Human) cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to oxidised low-density lipoprotein particle stimulus [GO:0140052]; COPII-coated vesicle cargo loading [GO:0090110]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; lipoprotein transport [GO:0042953]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell migration [GO:0030336]; negative regulation of leukocyte cell-cell adhesion [GO:1903038]; negative regulation of lymphocyte migration [GO:2000402]; positive regulation of leukocyte migration [GO:0002687]; protein localization to endoplasmic reticulum exit site [GO:0070973]; protein secretion [GO:0009306]; protein transport [GO:0015031]; vesicle cargo loading [GO:0035459]; wound healing [GO:0042060] endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020] cargo receptor activity [GO:0038024] 0.96941 -5.4969 AGLEDECKTLR 8.44074 11.1994 12.836 0 0 8.98741 10.7309 0 9.08138 10.0814 0 9.84987 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5JRC9 FA47A_HUMAN Protein FAM47A FAM47A Homo sapiens (Human) 0.96938 -3.9664 APCEGREK 0 0 0 0 0 0 0 0 0 0 9.47857 10.4205 0 0 0 10.3706 0 0 8.50132 0 0 9.6037 0 8.56484 0 0 0 Q5JRK9 GGEE3_HUMAN Putative G antigen family E member 3 (Prostate-associated gene 2B protein) (PAGE-2B) PAGE2B GAGEE3 Homo sapiens (Human) 0.84197 0.14208 EGIMPTFDLTK 0 0 9.36975 0 0 0 0 0 0 0 0 0 10.5028 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5JRX3 PREP_HUMAN "Presequence protease, mitochondrial (hPreP) (EC 3.4.24.-) (Pitrilysin metalloproteinase 1) (Metalloprotease 1) (hMP1)" PITRM1 KIAA1104 MP1 PREP Homo sapiens (Human) protein processing [GO:0016485]; protein targeting to mitochondrion [GO:0006626]; proteolysis [GO:0006508] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] enzyme activator activity [GO:0008047]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270] 0.96668 -2.3091 ACERALQYKLGDK 0 8.53718 0 0 10.0081 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.358 0 0 Q5JS13 RGPS1_HUMAN Ras-specific guanine nucleotide-releasing factor RalGPS1 (Ral GEF with PH domain and SH3-binding motif 1) (Ral guanine nucleotide exchange factor 2) (RalGEF 2) (RalA exchange factor RalGPS1) RALGPS1 KIAA0351 RALGEF2 Homo sapiens (Human) intracellular signal transduction [GO:0035556]; positive regulation of GTPase activity [GO:0043547]; Ras protein signal transduction [GO:0007265]; regulation of Ral protein signal transduction [GO:0032485] cytoplasm [GO:0005737]; plasma membrane [GO:0005886] guanyl-nucleotide exchange factor activity [GO:0005085] 0.88965 -0.4191 ARHLLDDSVLESR 0 0 0 0 0 0 0 0 0 0 11.7087 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5JSH3 WDR44_HUMAN WD repeat-containing protein 44 (Rabphilin-11) WDR44 RPH11 Homo sapiens (Human) cytosol [GO:0005829]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; perinuclear region of cytoplasm [GO:0048471] 0.96864 -3.9104 AKHLAEEYGER 0 0 0 0 0 8.44559 11.2805 0 0 0 0 0 0 0 9.65301 0 0 0 0 0 0 0 0 0 0 0 8.7651 Q5JSL3 DOC11_HUMAN Dedicator of cytokinesis protein 11 (Activated Cdc42-associated guanine nucleotide exchange factor) (ACG) (Zizimin-2) DOCK11 ZIZ2 Homo sapiens (Human) B cell homeostasis [GO:0001782]; marginal zone B cell differentiation [GO:0002315]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; small GTPase mediated signal transduction [GO:0007264] cytosol [GO:0005829] guanyl-nucleotide exchange factor activity [GO:0005085]; small GTPase binding [GO:0031267] 0.090909 1.2062 ELTERKTEFER 0 0 0 0 9.55882 0 0 0 0 0 0 0 0 0 9.8381 0 0 0 0 0 0 0 0 0 0 9.90941 0 Q5JSP0 FGD3_HUMAN "FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5)" FGD3 ZFYVE5 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cytoskeleton organization [GO:0007010]; filopodium assembly [GO:0046847]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; lamellipodium [GO:0030027]; ruffle [GO:0001726] guanyl-nucleotide exchange factor activity [GO:0005085]; metal ion binding [GO:0046872]; small GTPase binding [GO:0031267] 0.92666 -1.1852 LSSKTRR 0 0 0 0 0 0 0 9.80927 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5JST6 EFHC2_HUMAN EF-hand domain-containing family member C2 EFHC2 Homo sapiens (Human) cellular response to leukemia inhibitory factor [GO:1990830]; regulation of neuron projection development [GO:0010975] axonemal microtubule [GO:0005879]; ciliary basal body [GO:0036064] calcium ion binding [GO:0005509] 0.34994 0.76501 ELLPHSSGR 0 10.7106 0 0 0 0 0 0 0 0 0 9.44491 11.0808 0 11.3434 0 0 0 9.79084 0 0 0 0 0 0 0 0 Q5JSZ5 PRC2B_HUMAN Protein PRRC2B (HLA-B-associated transcript 2-like 1) (Proline-rich coiled-coil protein 2B) PRRC2B BAT2L BAT2L1 KIAA0515 Homo sapiens (Human) cell differentiation [GO:0030154] RNA binding [GO:0003723] 0.96902 -4.4382 AAGGQDK 12.9899 0 0 0 0 0 11.5984 0 0 0 13.8181 0 0 0 0 11.0042 0 0 0 9.64724 0 0 0 7.79448 8.49645 0 0 Q5JTC6 AMER1_HUMAN APC membrane recruitment protein 1 (Amer1) (Protein FAM123B) (Wilms tumor gene on the X chromosome protein) AMER1 FAM123B WTX Homo sapiens (Human) adipose tissue development [GO:0060612]; bone development [GO:0060348]; mesenchymal cell differentiation involved in kidney development [GO:0072161]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein ubiquitination [GO:0031398]; regulation of canonical Wnt signaling pathway [GO:0060828]; Wnt signaling pathway [GO:0016055] cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nuclear body [GO:0016604]; plasma membrane [GO:0005886] "beta-catenin binding [GO:0008013]; beta-catenin destruction complex binding [GO:1904713]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]" 0.95966 -1.82 EAHAREAYTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.40111 0 0 0 0 8.87685 0 0 0 0 0 0 0 Q5JTD0 TJAP1_HUMAN Tight junction-associated protein 1 (Protein incorporated later into tight junctions) (Tight junction protein 4) TJAP1 PILT TJP4 Homo sapiens (Human) Golgi organization [GO:0007030] bicellular tight junction [GO:0005923]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802] 0.9519 -1.4285 SHFRNHKFADLPCELQDMVR 9.5452 11.5985 11.4436 11.1365 11.2203 0 11.1898 11.0174 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5JTH9 RRP12_HUMAN RRP12-like protein RRP12 KIAA0690 Homo sapiens (Human) rRNA processing [GO:0006364] cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; plasma membrane [GO:0005886] RNA binding [GO:0003723] 0.93935 -1.3036 FIRKFGFELVK 0 0 0 0 0 0 0 0 0 0 0 0 0 8.85633 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5JTV8 TOIP1_HUMAN Torsin-1A-interacting protein 1 (Lamin-associated protein 1B) (LAP1B) TOR1AIP1 LAP1 Homo sapiens (Human) nuclear membrane organization [GO:0071763]; positive regulation of ATP-dependent activity [GO:0032781]; protein localization to nuclear envelope [GO:0090435]; protein localization to nucleus [GO:0034504] nuclear envelope [GO:0005635]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nucleus [GO:0005634] ATPase activator activity [GO:0001671]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; lamin binding [GO:0005521] 0.96921 -3.3761 SQTFLEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.01357 0 0 0 0 0 0 0 0 0 0 Q5JTW2 CEP78_HUMAN Centrosomal protein of 78 kDa (Cep78) CEP78 C9orf81 Homo sapiens (Human) cilium organization [GO:0044782] centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytosol [GO:0005829] 0.81678 0.22118 QNALGQMQNIQFQK 0 0 0 0 0 0 9.92945 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5JTZ9 SYAM_HUMAN "Alanine--tRNA ligase, mitochondrial (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)" AARS2 AARSL KIAA1270 Homo sapiens (Human) alanyl-tRNA aminoacylation [GO:0006419]; mitochondrial alanyl-tRNA aminoacylation [GO:0070143]; tRNA modification [GO:0006400] mitochondrion [GO:0005739] alanine-tRNA ligase activity [GO:0004813]; amino acid binding [GO:0016597]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270] 0.93751 -1.2932 AGLDPDLETR 0 0 0 0 0 0 11.1901 11.1067 0 0 0 0 0 0 0 0 9.77243 0 0 0 0 10.4072 0 0 0 0 0 Q5JU00 DRC5_HUMAN Dynein regulatory complex subunit 5 (T-complex-associated testis-expressed protein 1) (Tcte-1) TCTE1 DRC5 Homo sapiens (Human) flagellated sperm motility [GO:0030317]; microtubule-based movement [GO:0007018] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; sperm flagellum [GO:0036126] 0.34387 0.77084 GARGAAK 0 0 0 0 0 0 0 12.4611 12.5332 0 0 0 0 0 0 10.0729 0 0 0 0 0 0 0 0 0 0 0 Q5JU67 CF157_HUMAN Cilia- and flagella-associated protein 157 CFAP157 C9orf117 Homo sapiens (Human) sperm axoneme assembly [GO:0007288] ciliary basal body [GO:0036064]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886] microtubule binding [GO:0008017] 0.88452 -0.19612 EIIQRVNLVANEFHK 0 0 0 0 0 0 0 0 0 0 0 9.17976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5JU85 IQEC2_HUMAN IQ motif and SEC7 domain-containing protein 2 IQSEC2 KIAA0522 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; modulation of chemical synaptic transmission [GO:0050804]; regulation of ARF protein signal transduction [GO:0032012]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696] cytoplasm [GO:0005737]; Schaffer collateral - CA1 synapse [GO:0098685] guanyl-nucleotide exchange factor activity [GO:0005085] 0.96376 -2.4114 GPGCLECRDFR 0 0 0 0 0 0 0 0 0 0 9.92475 11.4991 0 0 0 0 0 0 9.539 0 0 0 0 8.84806 0 0 0 Q5JUK3 KCNT1_HUMAN Potassium channel subfamily T member 1 (KCa4.1) KCNT1 KIAA1422 Homo sapiens (Human) plasma membrane [GO:0005886] intracellular sodium activated potassium channel activity [GO:0005228]; outward rectifier potassium channel activity [GO:0015271] 0.92462 -1.0081 ITEGDLWIR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.93151 0 0 0 0 0 0 0 0 0 0 0 10.5721 0 Q5JUR7 TEX30_HUMAN Testis-expressed protein 30 TEX30 C13orf27 Homo sapiens (Human) 0.96752 -2.3331 LRDEDLFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4262 0 10.0301 0 0 0 0 0 0 0 0 Q5JV73 FRPD3_HUMAN FERM and PDZ domain-containing protein 3 FRMPD3 KIAA1817 Homo sapiens (Human) cytoskeleton [GO:0005856]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; tertiary granule membrane [GO:0070821] 0.96988 -4.4026 AVQSQEQGRHLR 0 0 10.9951 9.49825 0 10.0591 0 0 0 0 0 0 0 0 0 10.6409 0 0 0 0 0 0 0 0 0 0 0 Q5JVF3 PCID2_HUMAN PCI domain-containing protein 2 (CSN12-like protein) PCID2 HT004 Homo sapiens (Human) heterochromatin organization [GO:0070828]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lymphoid progenitor cell differentiation [GO:1905457]; negative regulation of transcription initiation by RNA polymerase II [GO:0060633]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; protein transport [GO:0015031]; regulation of mRNA stability [GO:0043488]; spleen development [GO:0048536]; transcription elongation by RNA polymerase II [GO:0006368] cytoplasm [GO:0005737]; nuclear pore nuclear basket [GO:0044615]; nucleus [GO:0005634]; transcription export complex 2 [GO:0070390] double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723] 0.78588 0.25954 VGDMLEKAAELLMSCFR 0 0 0 0 0 0 0 0 0 0 0 0 9.34574 0 0 0 0 0 0 0 0 9.40212 0 0 0 0 0 Q5JVG8 ZN506_HUMAN Zinc finger protein 506 ZNF506 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleolus [GO:0005730] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96961 -3.1121 HKRIHTGDVPYK 0 10.9767 0 0 0 0 0 0 0 0 0 10.0857 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5JVX7 CA141_HUMAN Uncharacterized protein C1orf141 C1orf141 Homo sapiens (Human) 0.88451 -0.28419 SPQMNDFNIKENK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.08036 0 0 0 0 0 0 0 0 0 0 0 Q5JW98 CAHM4_HUMAN Calcium homeostasis modulator protein 4 (Protein FAM26D) CALHM4 C6orf78 FAM26D UNQ6481/PRO21277 Homo sapiens (Human) membrane [GO:0016020] monoatomic cation channel activity [GO:0005261] 0.95203 -1.4462 ISPLECKLACLR 0 0 0 0 0 0 0 11.8722 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.58729 0 0 Q5JWR5 DOP1_HUMAN Protein dopey-1 DOP1A DOPEY1 KIAA1117 Homo sapiens (Human) Golgi to endosome transport [GO:0006895]; protein transport [GO:0015031] cytosol [GO:0005829]; endosome [GO:0005768]; Golgi membrane [GO:0000139]; trans-Golgi network [GO:0005802] 0.92447 -1.0079 LENHKPCSSK 0 0 0 0 0 0 0 9.57696 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5995 Q5JXB2 UE2NL_HUMAN Putative ubiquitin-conjugating enzyme E2 N-like (Epididymis tissue protein Li 174) UBE2NL Homo sapiens (Human) protein polyubiquitination [GO:0000209] extracellular exosome [GO:0070062]; nucleus [GO:0005634] ubiquitin conjugating enzyme activity [GO:0061631] 0 3.4349 IYHPNVDK 0 0 0 0 0 0 8.58909 0 0 0 9.43317 9.15261 0 0 11.5149 11.1862 0 0 9.15041 9.03419 8.73339 0 0 0 11.0579 10.9819 10.1235 Q5JXC2 MIIP_HUMAN Migration and invasion-inhibitory protein (IGFBP2-binding protein) (Invasion-inhibitory protein 45) (IIp45) MIIP IIP45 Homo sapiens (Human) negative regulation of cell migration [GO:0030336]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972] 0.14211 1.0301 VEAEELAQLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0295 0 0 0 0 0 0 0 0 0 0 0 Q5JY77 GASP1_HUMAN G-protein coupled receptor-associated sorting protein 1 (GASP-1) GPRASP1 GASP KIAA0443 Homo sapiens (Human) endosome to lysosome transport [GO:0008333]; G protein-coupled receptor catabolic process [GO:1990172] cytosol [GO:0005829]; nucleus [GO:0005634] 0.96909 -5.8808 DKTNTWSGPR 0 0 0 0 0 0 0 0 9.83078 9.87948 9.29106 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7432 0 9.19372 Q5K651 SAMD9_HUMAN Sterile alpha motif domain-containing protein 9 (SAM domain-containing protein 9) SAMD9 C7orf5 DRIF1 KIAA2004 OEF1 Homo sapiens (Human) endosomal vesicle fusion [GO:0034058]; innate immune response [GO:0045087] cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231] 0.97009 -5.2108 CHPDQTKHLDFLK 13.6364 13.843 11.57 11.9251 11.8886 12.4853 11.9637 12.1339 13.2275 11.6949 14.3731 14.4964 0 0 0 0 0 0 0 0 0 0 0 0 0 9.6824 0 Q5KSL6 DGKK_HUMAN Diacylglycerol kinase kappa (DAG kinase kappa) (DGK-kappa) (EC 2.7.1.107) (142 kDa diacylglycerol kinase) (Diglyceride kinase kappa) DGKK Homo sapiens (Human) diacylglycerol metabolic process [GO:0046339]; intracellular signal transduction [GO:0035556]; lipid phosphorylation [GO:0046834]; platelet activation [GO:0030168]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; response to oxidative stress [GO:0006979] plasma membrane [GO:0005886] ATP binding [GO:0005524]; diacylglycerol kinase activity [GO:0004143]; metal ion binding [GO:0046872] 0.84314 0.17592 IINLHHHR 0 0 0 0 0 0 9.02973 8.94295 0 0 0 0 0 9.20787 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5KU26 COL12_HUMAN Collectin-12 (Collectin placenta protein 1) (CL-P1) (hCL-P1) (Nurse cell scavenger receptor 2) (Scavenger receptor class A member 4) (Scavenger receptor with C-type lectin) COLEC12 CLP1 NSR2 SCARA4 SRCL Homo sapiens (Human) "carbohydrate mediated signaling [GO:0009756]; cellular response to exogenous dsRNA [GO:0071360]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, recognition [GO:0006910]; plasma membrane raft organization [GO:0044857]; toll-like receptor 3 signaling pathway [GO:0034138]" collagen trimer [GO:0005581]; endocytic vesicle membrane [GO:0030666]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886] galactose binding [GO:0005534]; low-density lipoprotein particle binding [GO:0030169]; metal ion binding [GO:0046872]; pattern recognition receptor activity [GO:0038187]; scavenger receptor activity [GO:0005044] 0.95142 -1.3997 EEQQWIKKQMVGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.225 0 0 8.99059 9.98641 0 0 0 0 0 0 0 Q5M775 CYTSB_HUMAN Cytospin-B (Nuclear structure protein 5) (NSP5) (Sperm antigen HCMOGT-1) (Sperm antigen with calponin homology and coiled-coil domains 1) SPECC1 CYTSB NSP5 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; associative learning [GO:0008306]; blastocyst development [GO:0001824] apical part of cell [GO:0045177]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; filamentous actin [GO:0031941]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; nucleoplasm [GO:0005654] 0.96963 -4.7064 ANGEIKHVSSLLAKVEK 0 0 0 0 0 0 10.7309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7.72744 0 0 0 0 0 Q5M7Z0 RNFT1_HUMAN E3 ubiquitin-protein ligase RNFT1 (EC 2.3.2.27) (Protein PTD016) (RING finger and transmembrane domain-containing protein 1) RNFT1 PTD016 Homo sapiens (Human) positive regulation of ERAD pathway [GO:1904294]; protein autoubiquitination [GO:0051865] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789] metal ion binding [GO:0046872]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630] 0.96281 -2.6298 ECAENASSR 0 0 12.4413 0 0 0 0 0 0 9.98726 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5M9N0 CD158_HUMAN Coiled-coil domain-containing protein 158 CCDC158 Homo sapiens (Human) 0.8973 -0.62744 DAMADIR 0 8.71273 0 0 0 0 10.6077 10.64 10.423 0 0 0 9.64135 0 0 0 0 10.2873 0 10.7591 0 0 0 0 10.0199 0 10.5122 Q5M9Q1 NKAPL_HUMAN NKAP-like protein NKAPL C6orf194 Homo sapiens (Human) cell differentiation [GO:0030154]; regulation of gene expression [GO:0010468]; spermatogenesis [GO:0007283] nucleus [GO:0005634] chromatin binding [GO:0003682] 0.44753 0.64419 GEIGLTSEEIGSFECSGYVMSGSR 0 9.50333 0 0 0 10.9205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5MAI5 CDKL4_HUMAN Cyclin-dependent kinase-like 4 (EC 2.7.11.22) CDKL4 Homo sapiens (Human) protein phosphorylation [GO:0006468] cytoplasm [GO:0005737]; nucleus [GO:0005634] ATP binding [GO:0005524]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein serine kinase activity [GO:0106310] 0.9138 -0.78275 RQQQAPK 0 10.2159 0 0 0 0 0 0 0 10.0823 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5MIZ7 P4R3B_HUMAN Serine/threonine-protein phosphatase 4 regulatory subunit 3B (SMEK homolog 2) PPP4R3B KIAA1387 PP4R3B SMEK2 Homo sapiens (Human) DNA damage response [GO:0006974]; gluconeogenesis [GO:0006094]; positive regulation of gluconeogenesis [GO:0045722]; protein dephosphorylation [GO:0006470]; regulation of double-strand break repair [GO:2000779] centrosome [GO:0005813]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; protein phosphatase 4 complex [GO:0030289] protein phosphatase activator activity [GO:0072542] 0.66049 0.39487 AKESEDKENLPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.60679 0 0 0 0 0 0 0 0 Q5MJ07 SPXN5_HUMAN Sperm protein associated with the nucleus on the X chromosome N5 (Nuclear-associated protein SPAN-Xn5) (SPANX-N5) (SPANX family member N5) SPANXN5 Homo sapiens (Human) 0.80166 0.23982 EKPTSSTNGEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.56609 0 Q5MJ09 SPXN3_HUMAN Sperm protein associated with the nucleus on the X chromosome N3 (Nuclear-associated protein SPAN-Xn3) (SPANX-N3) (SPANX family member N3) SPANXN3 Homo sapiens (Human) 0.90328 -0.70507 VLAPEQSLK 12.9899 12.8506 12.8119 11.61 11.6434 11.5034 13.3146 13.2447 13.2 13.5656 13.533 13.3483 10.5348 10.9753 12.3323 11.2204 11.2465 11.3424 0 0 0 0 0 0 0 0 0 Q5MJ70 SPDYA_HUMAN Speedy protein A (Rapid inducer of G2/M progression in oocytes A) (RINGO A) (hSpy/Ringo A) (Speedy-1) (Spy1) SPDYA SPDY1 SPY1 Homo sapiens (Human) DNA damage response [GO:0006974]; establishment of protein localization to telomere [GO:0070200]; G1/S transition of mitotic cell cycle [GO:0000082]; male meiotic nuclear division [GO:0007140]; meiotic attachment of telomere to nuclear envelope [GO:0070197]; oogenesis [GO:0048477]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of protein kinase activity [GO:0045860]; spermatogenesis [GO:0007283]; telomere capping [GO:0016233] "chromosome, telomeric region [GO:0000781]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; XY body [GO:0001741]" protein kinase activator activity [GO:0030295]; protein kinase binding [GO:0019901] 0.96965 -4.0442 NYNRDEVQLPR 9.92995 0 0 0 0 0 0 9.25581 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5MNV8 FBX47_HUMAN F-box only protein 47 FBXO47 Homo sapiens (Human) 0.92362 -1.0107 AVNGRTIELAR 0 0 0 0 0 0 0 0 0 10.5218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5MNZ6 WIPI3_HUMAN WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat-containing protein 45-like) (WDR45-like protein) (WD repeat-containing protein 45B) (WIPI49-like protein) WDR45B WDR45L WIPI3 Homo sapiens (Human) autophagosome assembly [GO:0000045]; autophagy of mitochondrion [GO:0000422]; autophagy of nucleus [GO:0044804]; cellular response to starvation [GO:0009267]; protein lipidation [GO:0006497]; protein localization to phagophore assembly site [GO:0034497] cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; lysosome [GO:0005764]; phagophore assembly site [GO:0000407]; phagophore assembly site membrane [GO:0034045] "phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; TSC1-TSC2 complex binding [GO:0062078]" 0.83303 0.19884 VMIWDDLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.453 0 0 0 0 0 0 0 0 Q5NDL2 EOGT_HUMAN EGF domain-specific O-linked N-acetylglucosamine transferase (EC 2.4.1.255) (Extracellular O-linked N-acetylglucosamine transferase) EOGT AER61 C3orf64 EOGT1 Homo sapiens (Human) protein O-GlcNAcylation via threonine [GO:0097370]; protein O-linked glycosylation [GO:0006493] endoplasmic reticulum lumen [GO:0005788] protein O-acetylglucosaminyltransferase activity [GO:0097363] 0.96331 -2.6773 CYLDLARLR 0 0 0 0 0 9.3087 0 0 0 0 0 0 0 0 0 0 10.1977 0 0 8.35478 0 0 0 9.52925 0 0 0 Q5NUL3 FFAR4_HUMAN Free fatty acid receptor 4 (G-protein coupled receptor 120) (G-protein coupled receptor 129) (G-protein coupled receptor GT01) (G-protein coupled receptor PGR4) (Omega-3 fatty acid receptor 1) FFAR4 GPR120 GPR129 O3FAR1 PGR4 Homo sapiens (Human) brown fat cell differentiation [GO:0050873]; cellular response to hormone stimulus [GO:0032870]; G protein-coupled receptor signaling pathway [GO:0007186]; ghrelin secretion [GO:0036321]; hormone secretion [GO:0046879]; inflammatory response [GO:0006954]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cytokine production [GO:0001818]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of somatostatin secretion [GO:0090275]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucagon secretion [GO:0070094]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of glucose transmembrane transport [GO:0010827]; white fat cell differentiation [GO:0050872] ciliary membrane [GO:0060170]; cilium [GO:0005929]; endocytic vesicle [GO:0030139]; endosome membrane [GO:0010008]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886] arrestin family protein binding [GO:1990763]; fatty acid binding [GO:0005504]; G protein-coupled receptor activity [GO:0004930]; peptide binding [GO:0042277]; taste receptor activity [GO:0008527] 0.96426 -2.4021 GAILTDTSVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9218 Q5PSV4 BRM1L_HUMAN Breast cancer metastasis-suppressor 1-like protein (BRMS1-homolog protein p40) (BRMS1-like protein p40) BRMS1L Homo sapiens (Human) histone deacetylation [GO:0016575]; negative regulation of cell migration [GO:0030336]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of stem cell population maintenance [GO:1902459] nucleus [GO:0005634]; Sin3 complex [GO:0016580]; Sin3-type complex [GO:0070822] histone deacetylase binding [GO:0042826] 0.96833 -3.6413 ELCLESVKNK 0 0 0 11.8042 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5QGS0 NEXMI_HUMAN Neurite extension and migration factor (XLMR protein related to neurite extension) (XPN) NEXMIF KIAA2022 Homo sapiens (Human) negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of neuron migration [GO:2001223]; nervous system development [GO:0007399] cytosol [GO:0005829]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.96949 -4.639 ETLMYPR 0 11.1002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.20149 0 0 0 0 0 0 0 Q5QJ38 TCHL1_HUMAN Trichohyalin-like protein 1 (Basalin) (Protein S100-A17) (S100 calcium-binding protein A17) TCHHL1 S100A17 THHL1 Homo sapiens (Human) transition metal ion binding [GO:0046914] 0.95058 -1.4116 DQFGEQEGNLATQSSPPK 0 0 9.6466 10.1012 0 0 10.1255 0 0 0 0 0 0 10.5191 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5QJE6 TDIF2_HUMAN Deoxynucleotidyltransferase terminal-interacting protein 2 (Estrogen receptor-binding protein) (LPTS-interacting protein 2) (LPTS-RP2) (Terminal deoxynucleotidyltransferase-interacting factor 2) (TdIF2) (TdT-interacting factor 2) DNTTIP2 ERBP TDIF2 Homo sapiens (Human) ribosomal small subunit biogenesis [GO:0042274]; RNA processing [GO:0006396] chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040] RNA binding [GO:0003723] 0.92175 -1.138 AANAAGK 12.5486 11.4229 10.4145 11.0819 0 0 10.3906 12.4663 12.3104 12.2154 12.4185 12.2693 9.37145 10.7094 11.171 0 0 11.8747 0 9.66244 0 0 0 0 0 0 0 Q5R387 PA2GC_HUMAN Putative inactive group IIC secretory phospholipase A2 (Phosphatidylcholine 2-acylhydrolase-like protein GIIC) PLA2G2C Homo sapiens (Human) arachidonic acid secretion [GO:0050482]; fatty acid biosynthetic process [GO:0006633]; lipid catabolic process [GO:0016042]; phosphatidylcholine metabolic process [GO:0046470]; phospholipid metabolic process [GO:0006644]; positive regulation of fibroblast proliferation [GO:0048146] extracellular region [GO:0005576] calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; phospholipid binding [GO:0005543]; signaling receptor binding [GO:0005102] 0.95495 -1.5204 QFSSQPRCGR 0 0 0 0 0 0 0 0 0 8.74943 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5R3F8 PPR29_HUMAN Protein phosphatase 1 regulatory subunit 29 (Extracellular leucine-rich repeat and fibronectin type III domain-containing protein 2) (Leucine-rich repeat and fibronectin type-III domain-containing protein 6) (Leucine-rich repeat-containing protein 62) ELFN2 KIAA1904 LRRC62 PPP1R29 Homo sapiens (Human) extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; membrane [GO:0016020] protein phosphatase inhibitor activity [GO:0004864] 0.81764 0.22072 DSTYSQLSPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.946 Q5RGS3 F74A1_HUMAN Protein FAM74A1 FAM74A1 Homo sapiens (Human) membrane [GO:0016020] 0.88244 -0.11518 QLRRCLQEDVER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.90325 0 0 0 0 0 0 0 0 0 0 0 Q5RHP9 ERIC3_HUMAN Glutamate-rich protein 3 ERICH3 C1orf173 Homo sapiens (Human) 0.9696 -3.5403 EDVEGEEMVTEAEANR 8.9926 0 0 9.3971 9.31354 0 8.58113 8.81471 0 0 0 0 0 0 0 0 0 0 0 9.72738 0 0 9.56624 0 0 9.38657 0 Q5RL73 RBM48_HUMAN RNA-binding protein 48 RBM48 C7orf64 HSPC304 Homo sapiens (Human) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681] RNA binding [GO:0003723] 0.95272 -1.4933 TQINSLKNSVACPGAQK 0 0 0 0 0 0 0 9.31759 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5S007 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin) LRRK2 PARK8 Homo sapiens (Human) "autophagy [GO:0006914]; calcium-mediated signaling [GO:0019722]; canonical Wnt signaling pathway [GO:0060070]; cellular response to dopamine [GO:1903351]; cellular response to manganese ion [GO:0071287]; cellular response to oxidative stress [GO:0034599]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; determination of adult lifespan [GO:0008340]; endocytosis [GO:0006897]; endoplasmic reticulum organization [GO:0007029]; excitatory postsynaptic potential [GO:0060079]; exploration behavior [GO:0035640]; Golgi organization [GO:0007030]; GTP metabolic process [GO:0046039]; intracellular distribution of mitochondria [GO:0048312]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; locomotory exploration behavior [GO:0035641]; lysosome organization [GO:0007040]; MAPK cascade [GO:0000165]; mitochondrion localization [GO:0051646]; mitochondrion organization [GO:0007005]; negative regulation of autophagosome assembly [GO:1902902]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of GTPase activity [GO:0034260]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of late endosome to lysosome transport [GO:1902823]; negative regulation of macroautophagy [GO:0016242]; negative regulation of neuron projection development [GO:0010977]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein binding [GO:0032091]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein processing [GO:0010955]; negative regulation of protein processing involved in protein targeting to mitochondrion [GO:1903217]; negative regulation of protein targeting to mitochondrion [GO:1903215]; negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation [GO:1903125]; neuromuscular junction development [GO:0007528]; neuron projection arborization [GO:0140058]; neuron projection morphogenesis [GO:0048812]; olfactory bulb development [GO:0021772]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphorylation [GO:0016310]; positive regulation of autophagy [GO:0010508]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of dopamine receptor signaling pathway [GO:0060161]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of programmed cell death [GO:0043068]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein autoubiquitination [GO:1902499]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; positive regulation of tumor necrosis factor production [GO:0032760]; protein autophosphorylation [GO:0046777]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein localization to endoplasmic reticulum exit site [GO:0070973]; protein localization to mitochondrion [GO:0070585]; protein phosphorylation [GO:0006468]; reactive oxygen species metabolic process [GO:0072593]; regulation of autophagy [GO:0010506]; regulation of branching morphogenesis of a nerve [GO:2000172]; regulation of CAMKK-AMPK signaling cascade [GO:1905289]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of dopamine receptor signaling pathway [GO:0060159]; regulation of ER to Golgi vesicle-mediated transport [GO:0060628]; regulation of kidney size [GO:0035564]; regulation of locomotion [GO:0040012]; regulation of lysosomal lumen pH [GO:0035751]; regulation of membrane potential [GO:0042391]; regulation of mitochondrial depolarization [GO:0051900]; regulation of mitochondrial fission [GO:0090140]; regulation of neuroblast proliferation [GO:1902692]; regulation of neuron death [GO:1901214]; regulation of neuron maturation [GO:0014041]; regulation of protein kinase A signaling [GO:0010738]; regulation of protein stability [GO:0031647]; regulation of retrograde transport, endosome to Golgi [GO:1905279]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of synaptic vesicle transport [GO:1902803]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]; striatum development [GO:0021756]; tangential migration from the subventricular zone to the olfactory bulb [GO:0022028]; Wnt signalosome assembly [GO:1904887]" "amphisome [GO:0044753]; autolysosome [GO:0044754]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; caveola neck [GO:0099400]; cytoplasm [GO:0005737]; cytoplasmic side of mitochondrial outer membrane [GO:0032473]; cytoplasmic vesicle [GO:0031410]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle [GO:0005798]; growth cone [GO:0030426]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; microvillus [GO:0005902]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; multivesicular body, internal vesicle [GO:0097487]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; presynaptic cytosol [GO:0099523]; ribonucleoprotein complex [GO:1990904]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; trans-Golgi network [GO:0005802]; Wnt signalosome [GO:1990909]" actin binding [GO:0003779]; ATP binding [GO:0005524]; beta-catenin destruction complex binding [GO:1904713]; clathrin binding [GO:0030276]; co-receptor binding [GO:0039706]; GTP binding [GO:0005525]; GTP-dependent protein kinase activity [GO:0034211]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; JUN kinase kinase kinase activity [GO:0004706]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; MAP kinase kinase kinase activity [GO:0004709]; microtubule binding [GO:0008017]; peroxidase inhibitor activity [GO:0036479]; protein homodimerization activity [GO:0042803]; protein kinase A binding [GO:0051018]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; signaling receptor binding [GO:0005102]; signaling receptor complex adaptor activity [GO:0030159]; small GTPase binding [GO:0031267]; SNARE binding [GO:0000149]; syntaxin-1 binding [GO:0017075]; transmembrane transporter binding [GO:0044325]; tubulin binding [GO:0015631] 0.89727 -0.54766 ALHVLFER 12.9899 0 0 0 11.6434 0 9.97685 0 10.0395 0 0 0 0 0 10.9837 0 0 0 0 8.23812 0 0 0 0 0 0 0 Q5SGD2 PPM1L_HUMAN Protein phosphatase 1L (EC 3.1.3.16) (Protein phosphatase 1-like) (Protein phosphatase 2C isoform epsilon) (PP2C-epsilon) PPM1L PP2CE Homo sapiens (Human) MAPK cascade [GO:0000165]; protein dephosphorylation [GO:0006470]; sphingolipid biosynthetic process [GO:0030148]; transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178] endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062] metal ion binding [GO:0046872]; myosin phosphatase activity [GO:0017018]; protein serine/threonine phosphatase activity [GO:0004722] 0.92066 -0.92084 FEVLTDLANK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.95809 0 0 0 0 0 0 Q5SNT2 TM201_HUMAN Transmembrane protein 201 (Spindle-associated membrane protein 1) TMEM201 NET5 SAMP1 Homo sapiens (Human) centrosome localization [GO:0051642]; fibroblast migration [GO:0010761]; nuclear envelope organization [GO:0006998]; nuclear migration along microtubule [GO:0030473]; protein localization to nuclear envelope [GO:0090435] cytoplasm [GO:0005737]; nuclear envelope [GO:0005635]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; spindle pole [GO:0000922] actin filament binding [GO:0051015]; lamin binding [GO:0005521] 0.95243 -1.46 QLAAFAPREEGRYDEEVEVYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.8847 0 0 0 0 0 0 0 0 0 0 0 0 Q5SNV9 CA167_HUMAN Uncharacterized protein C1orf167 C1orf167 Homo sapiens (Human) 0.88441 -0.20876 CQAPQEPPAWGVSPK 0 0 0 0 0 0 0 0 0 0 0 9.96362 0 10.3929 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5SQ64 LY66F_HUMAN Lymphocyte antigen 6 complex locus protein G6f LY6G6F C6orf21 G6F LY6G6D NG32 Homo sapiens (Human) plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092] 0.95301 -1.4911 IIRCLMTHNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.76233 0 Q5SQI0 ATAT_HUMAN Alpha-tubulin N-acetyltransferase 1 (Alpha-TAT) (Alpha-TAT1) (TAT) (EC 2.3.1.108) (Acetyltransferase mec-17 homolog) ATAT1 C6orf134 MEC17 Nbla00487 Homo sapiens (Human) alpha-tubulin acetylation [GO:0071929]; cilium assembly [GO:0060271]; dentate gyrus development [GO:0021542]; microtubule cytoskeleton organization [GO:0000226]; neuron development [GO:0048666]; NLRP3 inflammasome complex assembly [GO:0044546]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227]; regulation of fat cell differentiation [GO:0045598]; regulation of microtubule cytoskeleton organization [GO:0070507]; response to mechanical stimulus [GO:0009612]; response to pain [GO:0048265]; spermatogenesis [GO:0007283] axon [GO:0030424]; clathrin-coated pit [GO:0005905]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; microtubule [GO:0005874]; microtubule bundle [GO:0097427]; mitotic spindle [GO:0072686] "lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; tubulin N-acetyltransferase activity [GO:0019799]" 0.95434 -1.5024 ELFQYMLQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.51712 0 0 0 0 0 0 0 0 Q5SQN1 SNP47_HUMAN Synaptosomal-associated protein 47 (SNAP-47) (Epididymis luminal protein 170) (Synaptosomal-associated 47 kDa protein) SNAP47 C1orf142 HEL170 SVAP1 Homo sapiens (Human) exocytosis [GO:0006887]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle priming [GO:0016082] endomembrane system [GO:0012505]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; SNARE complex [GO:0031201] SNAP receptor activity [GO:0005484]; syntaxin binding [GO:0019905] 0.92552 -0.96844 EDVSMTSCEPFGK 0 8.67814 0 0 0 0 0 0 9.77525 0 9.64933 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8482 12.1184 Q5SQS7 SH24B_HUMAN SH2 domain-containing protein 4B SH2D4B Homo sapiens (Human) cytoplasm [GO:0005737] 0.9617 -2.5811 EWEEQLRRSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.6789 0 0 0 0 0 0 0 Q5SQS8 CJ120_HUMAN Uncharacterized protein C10orf120 C10orf120 Homo sapiens (Human) 0.85349 0.10644 LLAYKQEEECRMLK 0 0 11.3112 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1033 0 0 11.1877 0 Q5SRE5 NU188_HUMAN Nucleoporin NUP188 (hNup188) NUP188 KIAA0169 Homo sapiens (Human) mRNA transport [GO:0051028]; nucleocytoplasmic transport [GO:0006913]; protein import into nucleus [GO:0006606]; RNA export from nucleus [GO:0006405] cytosol [GO:0005829]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nuclear pore inner ring [GO:0044611] structural constituent of nuclear pore [GO:0017056] 0.96798 -2.755 AAIAFLHALWQDRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.47812 0 0 0 0 0 0 0 Q5SRH9 TT39A_HUMAN Tetratricopeptide repeat protein 39A (TPR repeat protein 39A) (Differentially expressed in MCF-7 with estradiol protein 6) (DEME-6) TTC39A C1orf34 KIAA0452 Homo sapiens (Human) centrosome [GO:0005813] 0.92272 -1.1033 LLESAKQNYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2564 0 0 0 8.87394 0 0 0 0 0 0 0 0 Q5SRN2 TSBP1_HUMAN Testis-expressed basic protein 1 (Uncharacterized protein C6orf10) TSBP1 C6orf10 Homo sapiens (Human) membrane [GO:0016020]; nucleus [GO:0005634] 0.96907 -4.491 DKIGMEVK 0 8.80035 0 0 0 0 0 0 0 0 11.3788 0 8.83958 0 9.55827 0 0 0 0 0 0 0 0 0 0 0 0 Q5SSJ5 HP1B3_HUMAN Heterochromatin protein 1-binding protein 3 (Protein HP1-BP74) HP1BP3 Homo sapiens (Human) cellular response to hypoxia [GO:0071456]; heterochromatin organization [GO:0070828]; nucleosome assembly [GO:0006334]; regulation of cell population proliferation [GO:0042127]; regulation of DNA-templated transcription [GO:0006355]; regulation of nucleus size [GO:0097298] chromosome [GO:0005694]; nuclear speck [GO:0016607]; nucleosome [GO:0000786]; nucleus [GO:0005634] DNA binding [GO:0003677]; nucleosome binding [GO:0031491] 0.95963 -1.7282 EASYSLIRKYVSQYYPK 0 0 0 0 0 0 0 0 0 0 0 10.7601 0 0 0 0 0 10.9665 10.9244 0 10.6931 0 0 10.2036 0 9.91631 10.3638 Q5SV97 PERM1_HUMAN PGC-1 and ERR-induced regulator in muscle protein 1 (PPARGC1 and ESRR-induced regulator in muscle 1) (Peroxisome proliferator-activated receptor gamma coactivator 1 and estrogen-related receptor-induced regulator in muscle 1) PERM1 C1orf170 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; response to muscle activity [GO:0014850] cytoplasm [GO:0005737]; nucleus [GO:0005634] 0.2726 0.84124 QVGQGRR 14.6688 14.5106 14.5667 0 0 0 14.6733 14.631 0 15.0724 0 14.7975 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5SVQ8 ZBT41_HUMAN Zinc finger and BTB domain-containing protein 41 ZBTB41 FRBZ1 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96923 -6.0495 IHSGEKAHQCEECGKCFGR 15.1318 15.2082 14.1335 12.2091 12.3558 12.0769 14.0851 14.4719 14.7589 12.6134 12.656 13.066 13.3681 14.2046 13.7743 13.673 13.9042 12.9942 0 10.1728 10.7921 0 9.90466 9.79752 9.38694 0 0 Q5SVZ6 ZMYM1_HUMAN Zinc finger MYM-type protein 1 ZMYM1 Homo sapiens (Human) nucleus [GO:0005634] protein dimerization activity [GO:0046983]; zinc ion binding [GO:0008270] 0.96341 -2.0986 DNMKSMKISDELCHPK 11.0912 0 9.58916 10.358 10.6189 8.45837 0 0 0 10.9496 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5SW24 DACT2_HUMAN Dapper homolog 2 (Dapper antagonist of catenin 2) DACT2 C6orf116 PP13671 Homo sapiens (Human) epithelial cell morphogenesis [GO:0003382]; hematopoietic progenitor cell differentiation [GO:0002244]; inner medullary collecting duct development [GO:0072061]; negative regulation of cell adhesion [GO:0007162]; negative regulation of nodal signaling pathway [GO:1900108]; skin development [GO:0043588] cytoplasm [GO:0005737] beta-catenin binding [GO:0008013]; delta-catenin binding [GO:0070097]; protein kinase A binding [GO:0051018]; protein kinase C binding [GO:0005080]; transcription factor binding [GO:0008134] 0.96183 -2.5603 AGGPLAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.19928 0 0 0 0 0 0 0 0 0 Q5SW79 CE170_HUMAN Centrosomal protein of 170 kDa (Cep170) (KARP-1-binding protein) (KARP1-binding protein) CEP170 FAM68A KAB KIAA0470 Homo sapiens (Human) centriolar subdistal appendage [GO:0120103]; centriole [GO:0005814]; centrosome [GO:0005813]; cytosol [GO:0005829]; microtubule [GO:0005874]; spindle [GO:0005819] 0.9693 -3.1925 DRCSTGSPSK 0 0 10.363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5SWL7 PRA14_HUMAN PRAME family member 14 PRAMEF14 Homo sapiens (Human) negative regulation of apoptotic process [GO:0043066]; negative regulation of cell differentiation [GO:0045596]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of cell population proliferation [GO:0008284] cytoplasm [GO:0005737] 0.8034 0.2385 DLLCHTSGLSK 0 0 8.3856 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.36606 0 0 0 0 0 0 0 0 0 Q5SWL8 PRA19_HUMAN PRAME family member 19 PRAMEF19 Homo sapiens (Human) negative regulation of apoptotic process [GO:0043066]; negative regulation of cell differentiation [GO:0045596]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of cell population proliferation [GO:0008284] cytoplasm [GO:0005737] 0.9552 -1.579 EVREPNR 0 0 0 9.74907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5SWX8 ODR4_HUMAN Protein odr-4 homolog (hODR-4) (LAG1-interacting protein) (Transactivated by transforming growth factor beta protein 1) ODR4 C1orf27 TTG1 TTG1A Homo sapiens (Human) protein localization [GO:0008104] membrane [GO:0016020] 0.8153 0.22134 VTLHICASTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0942 0 0 0 0 0 0 0 0 0 Q5SXM1 ZN678_HUMAN Zinc finger protein 678 ZNF678 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.83551 0.19366 CKECGKGFYQSSIHSK 0 0 0 0 10.2186 11.9681 0 14.0448 0 0 0 0 9.28418 0 0 12.8799 10.3228 0 11.241 11.4307 10.6755 0 10.9694 0 0 0 0 Q5SXM2 SNPC4_HUMAN snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha) (snRNA-activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) SNAPC4 SNAP190 Homo sapiens (Human) snRNA transcription by RNA polymerase II [GO:0042795]; snRNA transcription by RNA polymerase III [GO:0042796] nucleoplasm [GO:0005654]; nucleus [GO:0005634]; snRNA-activating protein complex [GO:0019185] DNA binding [GO:0003677]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III type 3 promoter sequence-specific DNA binding [GO:0001006] 0.96893 -4.2125 ATQSGQR 0 0 0 0 0 0 0 0 0 0 9.04486 0 0 0 0 9.57187 0 0 9.30711 0 0 0 0 0 0 0 0 Q5SY68 S1A7B_HUMAN Protein S100-A7-like 2 (S100 calcium-binding protein A7-like 2) S100A7L2 S100A7B Homo sapiens (Human) cytoplasm [GO:0005737]; extracellular space [GO:0005615] calcium ion binding [GO:0005509] 0 2.921 ENFPNFLSGCEK 0 0 0 0 0 0 0 0 0 0 0 0 9.73551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5SY80 CTSRE_HUMAN Cation channel sperm-associated auxiliary subunit epsilon (CatSper-epsilon) (CatSperepsilon) CATSPERE C1orf101 Homo sapiens (Human) flagellated sperm motility [GO:0030317]; sperm capacitation [GO:0048240] CatSper complex [GO:0036128]; sperm principal piece [GO:0097228] 0.92519 -0.97255 IVVPMTK 0 0 0 0 0 0 9.14965 0 0 0 0 0 0 0 0 9.51724 0 0 0 0 0 0 0 0 0 0 0 Q5SYB0 FRPD1_HUMAN FERM and PDZ domain-containing protein 1 (FERM domain-containing protein 2) FRMPD1 FRMD2 KIAA0967 Homo sapiens (Human) establishment of protein localization to membrane [GO:0090150]; regulation of G protein-coupled receptor signaling pathway [GO:0008277] cytoskeleton [GO:0005856]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] 0.95961 -1.964 AISFHMKR 0 9.11447 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5SYE7 NHSL1_HUMAN NHS-like protein 1 NHSL1 C6orf63 KIAA1357 Homo sapiens (Human) cell differentiation [GO:0030154] 0.96269 -2.5071 ANIQSLEPR 0 12.3509 0 0 0 0 0 12.9108 0 0 0 0 0 0 0 0 8.62388 0 0 0 0 0 0 0 0 0 0 Q5SZD1 CF141_HUMAN Uncharacterized protein C6orf141 C6orf141 Homo sapiens (Human) 0.96157 -2.5603 DAADPPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.68375 0 0 0 0 0 Q5SZJ8 BEND6_HUMAN BEN domain-containing protein 6 BEND6 C6orf65 Homo sapiens (Human) negative regulation of Notch signaling pathway [GO:0045746]; nervous system development [GO:0007399]; positive regulation of neuron differentiation [GO:0045666] nucleus [GO:0005634] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; transcription corepressor activity [GO:0003714] 0.36647 0.73969 IVQTDEITNTQAFR 0 0 0 0 0 11.5868 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0791 0 0 0 0 Q5SZK8 FREM2_HUMAN FRAS1-related extracellular matrix protein 2 (ECM3 homolog) FREM2 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell communication [GO:0007154]; embryonic digit morphogenesis [GO:0042733]; eye development [GO:0001654]; heart development [GO:0007507]; inner ear development [GO:0048839]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009] basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] metal ion binding [GO:0046872] 0.96848 -3.8515 EPVTFDLDIR 0 0 0 0 0 10.3821 8.53025 0 0 0 11.129 0 0 0 0 0 0 0 0 0 0 0 0 9.62143 0 0 0 Q5SZL2 CE85L_HUMAN Centrosomal protein of 85 kDa-like (Serologically defined breast cancer antigen NY-BR-15) CEP85L C6orf204 Homo sapiens (Human) neuron migration [GO:0001764] centrosome [GO:0005813]; cytoplasm [GO:0005737]; pericentriolar material [GO:0000242] 0.94396 -1.3368 AKALTSQLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1997 0 0 0 0 0 Q5SZQ8 CELF3_HUMAN CUGBP Elav-like family member 3 (CELF-3) (Bruno-like protein 1) (CAG repeat protein 4) (CUG-BP- and ETR-3-like factor 3) (ELAV-type RNA-binding protein 1) (ETR-1) (Expanded repeat domain protein CAG/CTG 4) (RNA-binding protein BRUNOL-1) (Trinucleotide repeat-containing gene 4 protein) CELF3 BRUNOL1 CAGH4 ERDA4 TNRC4 Homo sapiens (Human) "flagellated sperm motility [GO:0030317]; mRNA splice site selection [GO:0006376]; ncRNA transcription [GO:0098781]; nuclear body organization [GO:0030575]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]; spermatogenesis [GO:0007283]" cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] 7SK snRNA binding [GO:0097322]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723] 0.64055 0.39653 GPDGTSK 0 0 0 0 0 0 0 0 0 8.88258 8.74265 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5T011 SZT2_HUMAN KICSTOR complex protein SZT2 (Seizure threshold 2 protein homolog) SZT2 C1orf84 KIAA0467 Homo sapiens (Human) cellular response to amino acid starvation [GO:0034198]; cellular response to glucose starvation [GO:0042149]; central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; negative regulation of TORC1 signaling [GO:1904262]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; protein localization to lysosome [GO:0061462]; regulation of superoxide dismutase activity [GO:1901668] KICSTOR complex [GO:0140007]; lysosomal membrane [GO:0005765]; peroxisome [GO:0005777] 0.96862 -3.3453 APGSDSGAQRQK 0 12.4152 0 0 0 0 0 0 0 0 0 11.929 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5T036 F120S_HUMAN Uncharacterized protein FAM120AOS (FAM120A opposite strand protein) FAM120AOS C9orf10OS Homo sapiens (Human) 0.88803 -0.40741 AGGTRCPQRR 0 0 0 0 0 0 8.78018 0 0 9.65476 0 0 0 0 0 10.4536 9.24817 0 10.1387 0 0 0 0 9.74012 0 0 0 Q5T089 MORN1_HUMAN MORN repeat-containing protein 1 MORN1 Homo sapiens (Human) 0.8132 0.2215 AGGCYEGEVSHGMR 0 0 0 0 0 0 0 0 0 9.13656 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5T0F9 C2D1B_HUMAN Coiled-coil and C2 domain-containing protein 1B (Five prime repressor element under dual repression-binding protein 2) (FRE under dual repression-binding protein 2) (Freud-2) CC2D1B KIAA1836 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] intracellular membrane-bounded organelle [GO:0043231]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.89905 -0.56805 GQGVAAAK 0 0 0 0 0 0 8.36632 0 0 8.92659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5T0J3 CA220_HUMAN Putative uncharacterized protein C1orf220 C1orf220 Homo sapiens (Human) 0.78662 0.25799 GLWYCYLQVK 0 11.0641 0 0 0 0 0 0 0 0 0 11.314 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5T0J7 TEX35_HUMAN Testis-expressed protein 35 TEX35 C1orf49 Homo sapiens (Human) microtubule cytoskeleton [GO:0015630]; nucleus [GO:0005634] 0.92768 -1.2248 MDILINTQK 0 8.73444 0 0 0 0 9.84262 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5T0N5 FBP1L_HUMAN Formin-binding protein 1-like (Transducer of Cdc42-dependent actin assembly protein 1) (Toca-1) FNBP1L C1orf39 TOCA1 Homo sapiens (Human) autophagy [GO:0006914]; cilium assembly [GO:0060271]; clathrin-dependent endocytosis [GO:0072583]; membrane invagination [GO:0010324]; plasma membrane tubulation [GO:0097320]; positive regulation of filopodium assembly [GO:0051491]; signal transduction [GO:0007165]; vesicle budding from membrane [GO:0006900]; vesicle organization [GO:0016050]; vesicle transport along actin filament [GO:0030050] cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; plasma membrane [GO:0005886] cadherin binding [GO:0045296]; GTPase binding [GO:0051020]; lipid binding [GO:0008289] 0.42082 0.67151 GFADSER 0 0 0 0 0 0 0 0 0 0 0 0 8.77142 0 0 8.68895 0 0 0 0 0 0 9.95053 0 10.5041 0 0 Q5T0U0 CC122_HUMAN Coiled-coil domain-containing protein 122 CCDC122 Homo sapiens (Human) 0.63042 0.40953 KSQGFPK 12.8034 11.3243 0 9.21447 9.65885 9.48702 11.6566 11.023 0 0 0 0 9.99492 10.0541 0 10.389 10.8581 0 0 0 0 0 0 0 0 0 0 Q5T0W9 FA83B_HUMAN Protein FAM83B FAM83B C6orf143 Homo sapiens (Human) cell population proliferation [GO:0008283]; epidermal growth factor receptor signaling pathway [GO:0007173]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742] cytoplasm [GO:0005737]; membrane [GO:0016020] epidermal growth factor receptor binding [GO:0005154]; phosphatidylinositol 3-kinase catalytic subunit binding [GO:0036313]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein kinase binding [GO:0019901] 0.55993 0.52568 AGDASAPR 0 0 0 0 8.07687 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.63996 0 0 0 0 Q5T0Z8 CF132_HUMAN Uncharacterized protein C6orf132 C6orf132 Homo sapiens (Human) 0.75278 0.31021 EVAVVMPTLAR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0543 0 0 0 0 0 0 10.5009 9.90679 0 0 0 10.3409 0 Q5T160 SYRM_HUMAN "Probable arginine--tRNA ligase, mitochondrial (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS)" RARS2 RARSL Homo sapiens (Human) arginyl-tRNA aminoacylation [GO:0006420]; mitochondrial translation [GO:0032543]; tRNA aminoacylation for protein translation [GO:0006418] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] arginine-tRNA ligase activity [GO:0004814]; ATP binding [GO:0005524]; RNA binding [GO:0003723] 0.95915 -1.7724 DLSIEEYIRVYKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1599 11.2011 0 0 0 Q5T197 DCST1_HUMAN E3 ubiquitin-protein ligase DCST1 (EC 2.3.2.27) (DC-STAMP domain-containing protein 1) (RING-type E3 ubiquitin transferase) DCST1 Homo sapiens (Human) fusion of sperm to egg plasma membrane involved in single fertilization [GO:0007342]; innate immune response [GO:0045087]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; protein ubiquitination [GO:0016567]; sperm-egg recognition [GO:0035036]; ubiquitin-dependent protein catabolic process [GO:0006511] acrosomal membrane [GO:0002080]; plasma membrane [GO:0005886] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630] 0.96767 -2.7933 EGRLFVLGYALAAIYVGPVANLR 0 0 0 0 0 0 11.2256 11.2831 9.66085 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5T1B0 AXDN1_HUMAN Axonemal dynein light chain domain-containing protein 1 AXDND1 C1orf125 Homo sapiens (Human) 0.96897 -6.7131 ELCLVRAHDVKLTK 10.8638 11.0265 10.7105 9.61298 9.64423 9.71586 0 10.6054 10.5952 12.0894 11.9201 12.2067 8.68032 10.1558 0 0 9.60642 9.1532 0 0 0 0 0 0 0 0 13.6725 Q5T1C6 THEM4_HUMAN Acyl-coenzyme A thioesterase THEM4 (Acyl-CoA thioesterase THEM4) (EC 3.1.2.2) (Carboxyl-terminal modulator protein) (Thioesterase superfamily member 4) THEM4 CTMP Homo sapiens (Human) fatty acid metabolic process [GO:0006631]; protein kinase B signaling [GO:0043491]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108] cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587] myristoyl-CoA hydrolase activity [GO:0102991]; palmitoyl-CoA hydrolase activity [GO:0016290] 0.89877 -0.57294 LLFDQFMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14.0276 0 0 9.85437 9.81324 11.36 0 0 0 0 0 Q5T1H1 EYS_HUMAN Protein eyes shut homolog (Epidermal growth factor-like protein 10) (EGF-like protein 10) (Epidermal growth factor-like protein 11) (EGF-like protein 11) (Protein spacemaker homolog) EYS C6orf178 C6orf179 C6orf180 EGFL10 EGFL11 SPAM UNQ9424/PRO34591 Homo sapiens (Human) detection of light stimulus involved in visual perception [GO:0050908]; skeletal muscle tissue regeneration [GO:0043403] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; interphotoreceptor matrix [GO:0033165]; microtubule organizing center [GO:0005815]; photoreceptor outer segment [GO:0001750] calcium ion binding [GO:0005509] 0.95962 -1.9661 AGRVGAEGYLDLDGINVTEKASTK 9.56297 0 0 0 0 0 0 0 9.44456 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.43302 Q5T1M5 FKB15_HUMAN FK506-binding protein 15 (FKBP-15) (133 kDa FK506-binding protein) (133 kDa FKBP) (FKBP-133) (WASP- and FKBP-like protein) (WAFL) FKBP15 KIAA0674 Homo sapiens (Human) endocytosis [GO:0006897] actin cytoskeleton [GO:0015629]; early endosome [GO:0005769]; growth cone [GO:0030426]; membrane [GO:0016020] actin binding [GO:0003779]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755] 0.92499 -1.1761 SGEPALRTK 0 0 0 0 0 0 0 0 0 0 11.4322 11.3194 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5T1N1 AKND1_HUMAN Protein AKNAD1 AKNAD1 C1orf62 Homo sapiens (Human) 0.92688 -1.2178 ISGSKSLCDFDSTEEIK 0 0 0 0 0 0 0 9.73074 0 0 0 0 0 0 0 0 0 12.7545 0 0 0 0 0 0 0 0 0 Q5T1R4 ZEP3_HUMAN Transcription factor HIVEP3 (Human immunodeficiency virus type I enhancer-binding protein 3) (Kappa-B and V(D)J recombination signal sequences-binding protein) (Kappa-binding protein 1) (KBP-1) (Zinc finger protein ZAS3) HIVEP3 KBP1 KIAA1555 KRC ZAS3 Homo sapiens (Human) positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal muscle cell differentiation [GO:0035914] cytoplasm [GO:0005737]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96231 -2.033 AEGSPRK 0 0 0 0 0 0 0 0 0 0 0 9.82998 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5T200 ZC3HD_HUMAN Zinc finger CCCH domain-containing protein 13 ZC3H13 KIAA0853 Homo sapiens (Human) mRNA methylation [GO:0080009]; mRNA processing [GO:0006397]; regulation of stem cell population maintenance [GO:2000036]; RNA splicing [GO:0008380] nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA N6-methyladenosine methyltransferase complex [GO:0036396] metal ion binding [GO:0046872]; RNA binding [GO:0003723] 0.9689 -16.369 DADKDWPR 0 0 9.84731 0 0 11.2178 8.90421 9.65966 0 0 12.0514 0 11.1847 9.13042 0 9.13054 0 0 0 11.0995 0 0 9.2075 0 9.51625 0 0 Q5T2D2 TRML2_HUMAN Trem-like transcript 2 protein (TLT-2) (Triggering receptor expressed on myeloid cells-like protein 2) TREML2 C6orf76 TLT2 UNQ6268/PRO20473 Homo sapiens (Human) T cell activation [GO:0042110] cell surface [GO:0009986]; plasma membrane [GO:0005886] signaling receptor activity [GO:0038023] 0.95964 -1.8149 HMASYSMCSDPSTR 0 0 0 0 0 9.26388 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5T2D3 OTUD3_HUMAN OTU domain-containing protein 3 (EC 3.4.19.12) OTUD3 KIAA0459 Homo sapiens (Human) cellular response to nutrient levels [GO:0031669]; negative regulation of protein kinase B signaling [GO:0051898]; protein deubiquitination [GO:0016579]; protein K11-linked deubiquitination [GO:0035871]; protein K27-linked deubiquitination [GO:1990167]; protein K48-linked deubiquitination [GO:0071108]; protein K6-linked deubiquitination [GO:0044313]; protein stabilization [GO:0050821] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] cysteine-type deubiquitinase activity [GO:0004843] 0.92577 -0.98284 QETVDYMIK 0 0 0 0 0 0 0 10.5471 0 0 10.9803 0 10.9159 0 0 0 0 0 0 10.2796 0 0 0 0 12.1954 0 11.6109 Q5T2R2 DPS1_HUMAN All trans-polyprenyl-diphosphate synthase PDSS1 (All-trans-decaprenyl-diphosphate synthase subunit 1) (EC 2.5.1.91) (Decaprenyl pyrophosphate synthase subunit 1) (Decaprenyl-diphosphate synthase subunit 1) (Solanesyl-diphosphate synthase subunit 1) (Trans-prenyltransferase 1) (TPT 1) PDSS1 DPS1 TPRT Homo sapiens (Human) isoprenoid biosynthetic process [GO:0008299]; ubiquinone biosynthetic process [GO:0006744] mitochondrial matrix [GO:0005759]; transferase complex [GO:1990234] all-trans-decaprenyl-diphosphate synthase activity [GO:0097269]; all-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) activity [GO:0052923]; metal ion binding [GO:0046872]; prenyltransferase activity [GO:0004659]; protein heterodimerization activity [GO:0046982]; trans-hexaprenyltranstransferase activity [GO:0000010] 0.96993 -5.382 FAHYLEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.30492 0 Q5T2S8 ODAD2_HUMAN Outer dynein arm-docking complex subunit 2 (Armadillo repeat-containing protein 4) ODAD2 ARMC4 Homo sapiens (Human) cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; outer dynein arm assembly [GO:0036158]; regulation of cilium beat frequency [GO:0003356]; ventricular system development [GO:0021591] axoneme [GO:0005930]; ciliary base [GO:0097546] 0.55122 0.56093 DDDPESEIK 0 0 0 0 0 0 0 9.75674 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5T2W1 NHRF3_HUMAN Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (NHERF-3) (CFTR-associated protein of 70 kDa) (Na(+)/H(+) exchanger regulatory factor 3) (Na/Pi cotransporter C-terminal-associated protein 1) (NaPi-Cap1) (PDZ domain-containing protein 1) (Sodium-hydrogen exchanger regulatory factor 3) PDZK1 CAP70 NHERF3 PDZD1 Homo sapiens (Human) carnitine transport [GO:0015879]; positive regulation of cation transmembrane transport [GO:1904064]; positive regulation of ion transmembrane transporter activity [GO:0032414]; positive regulation of protein localization to membrane [GO:1905477]; positive regulation of protein targeting to membrane [GO:0090314]; protein localization to plasma membrane [GO:0072659]; regulation of monoatomic anion transport [GO:0044070]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961] apical plasma membrane [GO:0016324]; brush border [GO:0005903]; brush border membrane [GO:0031526]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886] PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; protein-membrane adaptor activity [GO:0043495]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102] 0.88494 -0.21749 AGLQDGDR 0 0 0 0 0 0 0 12.2775 0 0 0 0 0 0 0 10.6945 0 0 9.34631 0 0 0 0 0 0 0 0 Q5T319 F182B_HUMAN Protein FAM182B FAM182B Homo sapiens (Human) 0.95427 -1.5241 LLVWQKSVHK 0 0 0 0 0 0 0 0 0 0 0 0 0 12.1768 0 0 0 0 0 0 10.7152 0 0 0 0 0 0 Q5T3I0 GPTC4_HUMAN G patch domain-containing protein 4 GPATCH4 GPATC4 Homo sapiens (Human) nucleolus [GO:0005730] RNA binding [GO:0003723] 0.84892 0.16405 AGVSTVQK 0 0 0 9.87367 0 0 0 0 0 0 0 0 11.9792 0 12.0476 0 0 0 0 0 0 0 0 0 0 0 0 Q5T3J3 LRIF1_HUMAN Ligand-dependent nuclear receptor-interacting factor 1 (HP1-binding protein enriched in inactive X chromosome protein 1) (HBiX1) (Receptor-interacting factor 1) LRIF1 C1orf103 RIF1 Homo sapiens (Human) dosage compensation by inactivation of X chromosome [GO:0009048]; regulation of DNA-templated transcription [GO:0006355] Barr body [GO:0001740]; centriolar satellite [GO:0034451]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654] nuclear retinoic acid receptor binding [GO:0042974] 0.88786 -0.4082 GAQGRNDKK 0 0 0 0 0 0 0 0 10.2363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5T3U5 MRP7_HUMAN ATP-binding cassette sub-family C member 10 (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 7) ABCC10 MRP7 SIMRP7 Homo sapiens (Human) leukotriene metabolic process [GO:0006691]; leukotriene transport [GO:0071716]; lipid transport [GO:0006869]; transmembrane transport [GO:0055085] basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886] ABC-type glutathione S-conjugate transporter activity [GO:0015431]; ABC-type transporter activity [GO:0140359]; ABC-type xenobiotic transporter activity [GO:0008559]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled inorganic anion transmembrane transporter activity [GO:0043225]; ATPase-coupled transmembrane transporter activity [GO:0042626] 0.36175 0.74878 ALWQALK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.26097 0 0 0 0 0 0 10.8741 0 Q5T447 HECD3_HUMAN E3 ubiquitin-protein ligase HECTD3 (EC 2.3.2.26) (HECT domain-containing protein 3) (HECT-type E3 ubiquitin transferase HECTD3) HECTD3 Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567] perinuclear region of cytoplasm [GO:0048471] syntaxin binding [GO:0019905]; ubiquitin-protein transferase activity [GO:0004842] 0.96894 -4.219 DPAGPSR 0 0 0 0 0 0 0 0 9.67756 9.10305 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.21813 0 0 Q5T481 RBM20_HUMAN RNA-binding protein 20 (RNA-binding motif protein 20) RBM20 Homo sapiens (Human) "heart formation [GO:0060914]; mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of RNA splicing [GO:0033120]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]" cytoplasmic ribonucleoprotein granule [GO:0036464]; nucleus [GO:0005634] mRNA binding [GO:0003729]; pre-mRNA intronic binding [GO:0097157]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]; zinc ion binding [GO:0008270] 0.95263 -1.4591 ASPPIETDLQNQACQEVLTPENSRYVEMK 0 0 0 0 0 0 0 10.58 0 0 0 10.7231 0 0 0 9.50144 0 0 0 0 0 0 0 0 0 0 0 Q5T4B2 GT253_HUMAN Inactive glycosyltransferase 25 family member 3 (Cerebral endothelial cell adhesion molecule) CERCAM CEECAM1 GLT25D3 KIAA1502 Homo sapiens (Human) cell adhesion [GO:0007155]; leukocyte cell-cell adhesion [GO:0007159] endoplasmic reticulum lumen [GO:0005788]; plasma membrane [GO:0005886] identical protein binding [GO:0042802] 0.78767 0.2479 FYPDEEGPKHWTKER 0 0 0 0 0 0 0 0 0 0 12.1052 9.87664 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5T4D3 TMTC4_HUMAN Protein O-mannosyl-transferase TMTC4 (EC 2.4.1.109) (Transmembrane and TPR repeat-containing protein 4) TMTC4 Homo sapiens (Human) endoplasmic reticulum unfolded protein response [GO:0030968]; outer hair cell apoptotic process [GO:1905584]; positive regulation of endoplasmic reticulum calcium ion concentration [GO:0032470]; protein O-linked mannosylation [GO:0035269]; sensory perception of sound [GO:0007605] endoplasmic reticulum [GO:0005783]; membrane [GO:0016020] ATPase binding [GO:0051117]; dolichyl-phosphate-mannose-protein mannosyltransferase activity [GO:0004169]; mannosyltransferase activity [GO:0000030] 0.91474 -0.82941 HVDALNAWR 0 0 0 0 9.54386 9.6893 0 11.3375 0 10.808 0 10.8512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5T4F7 SFRP5_HUMAN Secreted frizzled-related protein 5 (sFRP-5) (Frizzled-related protein 1b) (FRP-1b) (Secreted apoptosis-related protein 3) (SARP-3) SFRP5 FRP1B SARP3 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; apoptotic process [GO:0006915]; canonical Wnt signaling pathway [GO:0060070]; cell differentiation [GO:0030154]; establishment or maintenance of cell polarity [GO:0007163]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of Wnt signaling pathway [GO:0030178]; negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis [GO:2000057]; non-canonical Wnt signaling pathway [GO:0035567]; signal transduction [GO:0007165]; visual perception [GO:0007601] extracellular space [GO:0005615] Wnt-protein binding [GO:0017147] 0.91607 -0.77298 VDGQLLLMAVYRWDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3048 0 Q5T4S7 UBR4_HUMAN E3 ubiquitin-protein ligase UBR4 (EC 2.3.2.27) (600 kDa retinoblastoma protein-associated factor) (N-recognin-4) (RING-type E3 ubiquitin transferase UBR4) (Retinoblastoma-associated factor of 600 kDa) (RBAF600) (p600) (Zinc finger UBR1-type protein 1) UBR4 KIAA0462 KIAA1307 RBAF600 ZUBR1 Homo sapiens (Human) negative regulation of fatty acid biosynthetic process [GO:0045717]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] centrosome [GO:0005813]; cytosol [GO:0005829]; ficolin-1-rich granule membrane [GO:0101003]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821] calmodulin binding [GO:0005516]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.96997 -5.2909 DLHTLDSHVR 0 8.98761 9.89698 8.92062 9.29928 9.2274 10.0353 10.0076 12.2637 9.74569 8.7936 0 0 9.4887 8.96437 10.8449 10.0974 0 12.4292 0 8.28272 10.3175 0 10.732 10.401 0 0 Q5T4T6 SYC2L_HUMAN Synaptonemal complex protein 2-like (SCP-2-like) (145 kDa nucleolar protein homolog) (hsNO145) SYCP2L C6orf177 NO145 Homo sapiens (Human) meiotic nuclear division [GO:0140013]; negative regulation of programmed cell death [GO:0043069] "condensed chromosome, centromeric region [GO:0000779]; female germ cell nucleus [GO:0001674]; lateral element [GO:0000800]; nucleoplasm [GO:0005654]" 0.60863 0.43122 EVLEFWGK 0 0 0 0 0 0 0 0 0 0 10.332 0 0 0 12.6178 0 13.2704 13.0451 0 10.3416 0 9.59358 10.0312 0 0 0 0 Q5T4W7 ARTN_HUMAN Artemin (Enovin) (Neublastin) ARTN EVN Homo sapiens (Human) axon guidance [GO:0007411]; induction of positive chemotaxis [GO:0050930]; lymphocyte migration into lymphoid organs [GO:0097021]; neuroblast proliferation [GO:0007405]; peripheral nervous system development [GO:0007422]; Peyer's patch morphogenesis [GO:0061146]; signal transduction [GO:0007165] extracellular region [GO:0005576]; extracellular space [GO:0005615] glial cell-derived neurotrophic factor receptor binding [GO:0030116]; growth factor activity [GO:0008083]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102] 0.96383 -2.4085 AGGPGSR 0 0 0 0 8.87529 10.1053 0 0 0 0 10.5967 0 0 0 0 0 8.93987 0 0 0 0 0 0 0 0 0 0 Q5T5B0 LCE3E_HUMAN Late cornified envelope protein 3E (Late envelope protein 17) LCE3E LEP17 Homo sapiens (Human) keratinization [GO:0031424] 0.9477 -1.3537 QCQPPPKCPSPKCPPK 0 0 0 0 0 0 9.71217 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5T5C0 STXB5_HUMAN Syntaxin-binding protein 5 (Lethal(2) giant larvae protein homolog 3) (Tomosyn-1) STXBP5 LLGL3 Homo sapiens (Human) exocytosis [GO:0006887]; positive regulation of exocytosis [GO:0045921]; protein transport [GO:0015031]; regulation of exocytosis [GO:0017157]; regulation of protein secretion [GO:0050708]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of synaptic vesicle priming [GO:0010807] acetylcholine-gated channel complex [GO:0005892]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of neuronal dense core vesicle membrane [GO:0098674]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; plasma membrane [GO:0005886]; SNARE complex [GO:0031201]; synaptic vesicle [GO:0008021] GTPase activator activity [GO:0005096]; myosin II binding [GO:0045159]; syntaxin binding [GO:0019905]; syntaxin-1 binding [GO:0017075] 0.95324 -1.4848 EPEIQETLQSEHFQLCKTVR 0 0 0 0 0 16.342 0 17.9666 18.0053 16.8612 0 0 0 0 0 0 0 16.272 0 0 0 0 0 0 0 12.3572 0 Q5T5D7 ZN684_HUMAN Zinc finger protein 684 ZNF684 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.94733 -1.3589 AYSRKAHLATHQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.54382 0 0 0 0 0 0 0 0 0 0 0 0 Q5T5J6 SWT1_HUMAN Transcriptional protein SWT1 SWT1 C1orf26 Homo sapiens (Human) nucleus [GO:0005634] 0.9692 -4.5616 AETTPLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.79834 0 0 0 0 0 9.66897 0 0 0 0 Q5T5M9 CCNJ_HUMAN Cyclin-J CCNJ Homo sapiens (Human) mitotic cell cycle phase transition [GO:0044772]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079] cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; nucleus [GO:0005634] cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538] 0.95465 -1.5068 IILRLSPTWPTR 0 0 9.20931 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5T5N4 CF118_HUMAN Uncharacterized protein C6orf118 C6orf118 Homo sapiens (Human) 0.97013 -3.2387 CEILSKWDEIQALEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4996 0 0 0 Q5T5P2 SKT_HUMAN Sickle tail protein homolog KIAA1217 SKT Homo sapiens (Human) embryonic skeletal system development [GO:0048706] centrosome [GO:0005813]; cytoplasm [GO:0005737] 0.51601 0.59394 GPITSYSK 0 13.7381 13.5503 12.8473 12.9228 0 0 13.3959 13.2356 0 0 10.0562 12.2063 0 0 12.7892 12.6478 0 0 0 0 0 0 7.80116 0 10.8487 9.52105 Q5T5S1 CC183_HUMAN Coiled-coil domain-containing protein 183 CCDC183 KIAA1984 Homo sapiens (Human) 0.96978 -4.6955 EASFIEER 0 0 0 0 0 10.5974 0 0 0 9.24022 0 10.6833 0 10.3147 0 8.99769 0 0 0 0 0 0 8.60648 0 0 0 10.7365 Q5T5U3 RHG21_HUMAN Rho GTPase-activating protein 21 (Rho GTPase-activating protein 10) (Rho-type GTPase-activating protein 21) ARHGAP21 ARHGAP10 KIAA1424 Homo sapiens (Human) establishment of Golgi localization [GO:0051683]; Golgi localization [GO:0051645]; Golgi organization [GO:0007030]; maintenance of Golgi location [GO:0051684]; organelle transport along microtubule [GO:0072384]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] actin cytoskeleton [GO:0015629]; anchoring junction [GO:0070161]; cell junction [GO:0030054]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886] GTPase activator activity [GO:0005096] 0.96812 -2.7745 APADDMFGVGNHK 0 0 0 0 8.7962 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3033 9.15294 8.92656 0 10.196 0 0 0 Q5T5Y3 CAMP1_HUMAN Calmodulin-regulated spectrin-associated protein 1 CAMSAP1 Homo sapiens (Human) cytoskeleton organization [GO:0007010]; microtubule cytoskeleton organization [GO:0000226]; neuron projection development [GO:0031175]; regulation of cell morphogenesis [GO:0022604]; regulation of microtubule polymerization [GO:0031113] cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule organizing center [GO:0005815] calmodulin binding [GO:0005516]; microtubule binding [GO:0008017]; microtubule minus-end binding [GO:0051011]; spectrin binding [GO:0030507] 0.96894 -4.2149 AAAEGWRK 11.5407 11.6057 0 10.3996 10.4157 10.4468 11.3144 0 0 0 9.85298 0 0 0 10.9709 10.0841 10.0885 0 11.4305 10.5862 0 10.603 0 9.74012 0 0 0 Q5T655 CFA58_HUMAN Cilia- and flagella-associated protein 58 (Coiled-coil domain-containing protein 147) CFAP58 C10orf80 CCDC147 Homo sapiens (Human) cilium assembly [GO:0060271]; flagellated sperm motility [GO:0030317]; Notch signaling pathway [GO:0007219]; protein localization to motile cilium [GO:0120229]; sperm axoneme assembly [GO:0007288]; sperm flagellum assembly [GO:0120316]; sperm mitochondrial sheath assembly [GO:0120317] centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; extracellular space [GO:0005615]; sperm flagellum [GO:0036126]; sperm midpiece [GO:0097225] 0.96873 -3.3198 EKETLKAELQK 11.2668 0 0 0 0 0 0 0 9.43804 10.7851 0 0 0 0 9.44118 11.9759 11.1437 9.5328 0 0 0 0 0 0 0 0 0 Q5T681 CJ062_HUMAN Uncharacterized protein C10orf62 C10orf62 Homo sapiens (Human) 0.96847 -3.8467 DKSPESHK 0 0 0 0 0 0 0 0 0 0 0 0 9.44684 0 0 0 0 10.5069 0 0 0 9.12531 0 0 0 0 0 Q5T6C5 AT7L2_HUMAN Ataxin-7-like protein 2 ATXN7L2 Homo sapiens (Human) 0.69377 0.38363 DGVEVEAPSRKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6041 0 0 0 0 0 0 0 0 0 0 0 Q5T6F0 DCA12_HUMAN DDB1- and CUL4-associated factor 12 (Centrosome-related protein TCC52) (Testis cancer centrosome-related protein) (WD repeat-containing protein 40A) DCAF12 KIAA1892 TCC52 WDR40A Homo sapiens (Human) protein ubiquitination [GO:0016567]; regulation of autophagy [GO:0010506]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] centrosome [GO:0005813]; Cul4-RING E3 ubiquitin ligase complex [GO:0080008]; cytoplasm [GO:0005737]; nucleus [GO:0005634] ubiquitin ligase-substrate adaptor activity [GO:1990756] 0.89867 -0.61744 ALKDIPK 9.40374 9.29237 0 0 0 0 9.46146 0 9.23668 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5T6F2 UBAP2_HUMAN Ubiquitin-associated protein 2 (UBAP-2) (RNA polymerase II degradation factor UBAP2) UBAP2 KIAA1491 Homo sapiens (Human) regulation of gene expression [GO:0010468] chromosome [GO:0005694]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; P-body [GO:0000932] cadherin binding [GO:0045296]; RNA binding [GO:0003723] 0.40678 0.69618 GVSVSSSTTGLPDMTGSVYNK 0 0 0 0 0 0 0 0 0 0 0 0 8.68559 10.2971 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5T6L9 EMARD_HUMAN Endoplasmic reticulum membrane-associated RNA degradation protein (ER membrane-associated RNA degradation protein) ERMARD C6orf70 Homo sapiens (Human) endoplasmic reticulum membrane [GO:0005789] 0.84207 0.17841 ELCSTPVPTLFCPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.39549 0 0 0 0 0 0 0 0 0 0 Q5T749 KPRP_HUMAN Keratinocyte proline-rich protein (hKPRP) KPRP C1orf45 Homo sapiens (Human) cytoplasm [GO:0005737]; extracellular exosome [GO:0070062] 0.80254 0.23984 SEPIYNSR 0 0 0 0 0 0 0 0 0 8.84464 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5T764 IFT1B_HUMAN Interferon-induced protein with tetratricopeptide repeats 1B (Interferon-induced protein with tetratricopeptide repeats 1-like protein) IFIT1B IFIT1L Homo sapiens (Human) defense response to virus [GO:0051607] cytosol [GO:0005829] RNA binding [GO:0003723] 0.96621 -2.3548 AEEHFQKGLRMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5586 0 0 Q5T7B8 KIF24_HUMAN Kinesin-like protein KIF24 KIF24 C9orf48 Homo sapiens (Human) cilium assembly [GO:0060271]; microtubule depolymerization [GO:0007019]; microtubule-based movement [GO:0007018]; negative regulation of cilium assembly [GO:1902018] centriole [GO:0005814]; centrosome [GO:0005813]; cytosol [GO:0005829]; microtubule [GO:0005874]; protein-containing complex [GO:0032991] ATP binding [GO:0005524]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777] 0.93414 -1.2896 CCTSVTSRNRTSGNSSPK 0 0 8.75004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.3773 0 0 10.3202 11.3633 Q5T7M9 DIK1A_HUMAN Divergent protein kinase domain 1A (Protein FAM69A) DIPK1A FAM69A Homo sapiens (Human) endoplasmic reticulum membrane [GO:0005789] 0.89047 -0.49449 GAPSEIREELEK 15.0194 14.9017 14.929 13.6061 13.341 13.4824 15.2989 15.2489 15.2254 15.5185 15.3086 15.2481 12.73 0 13.805 13.3851 13.4193 13.3898 0 0 0 11.9356 11.9226 11.8655 10.3429 10.7759 0 Q5T7N3 KANK4_HUMAN KN motif and ankyrin repeat domain-containing protein 4 (Ankyrin repeat domain-containing protein 38) KANK4 ANKRD38 Homo sapiens (Human) negative regulation of actin filament polymerization [GO:0030837] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; microtubule cytoskeleton [GO:0015630] 0.67968 0.39218 AGGNGTK 9.33755 0 8.30615 0 0 0 10.0741 9.92867 9.63668 0 0 10.4573 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5T7N8 F27D1_HUMAN Protein FAM27D1 FAM27D1 Homo sapiens (Human) 0.84783 0.16697 LTPTNTVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0937 Q5T7V8 GORAB_HUMAN RAB6-interacting golgin (N-terminal kinase-like-binding protein 1) (NTKL-BP1) (NTKL-binding protein 1) (hNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-BP1) (SCYL1-binding protein 1) GORAB NTKLBP1 SCYL1BP1 Homo sapiens (Human) hair follicle morphogenesis [GO:0031069]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901622] cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] 0.87177 0.064961 LLHEQEVESR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.40442 0 0 0 0 9.84928 0 0 0 0 0 0 0 Q5T7W7 TSTD2_HUMAN Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2 (Rhodanese domain-containing protein 2) TSTD2 C9orf97 PP4189 Homo sapiens (Human) 0.94715 -1.3557 FSDLDLK 0 0 0 0 0 0 0 0 0 9.86538 0 0 0 0 0 0 0 0 0 0 0 9.22337 0 0 0 0 0 Q5T890 ER6L2_HUMAN DNA excision repair protein ERCC-6-like 2 (EC 3.6.4.-) (DNA repair and recombination protein RAD26-like) ERCC6L2 C9orf102 RAD26L Homo sapiens (Human) cellular response to reactive oxygen species [GO:0034614]; interstrand cross-link repair [GO:0036297] cytoplasm [GO:0005737]; microtubule organizing center [GO:0005815]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] ATP binding [GO:0005524]; ATP-dependent chromatin remodeler activity [GO:0140658]; DNA binding [GO:0003677]; helicase activity [GO:0004386]; hydrolase activity [GO:0016787]; protein kinase binding [GO:0019901] 0.95121 -1.4315 QFEEMASYFNSSSVNEFAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5892 0 0 0 0 0 0 Q5T8A7 PPR26_HUMAN Protein phosphatase 1 regulatory subunit 26 PPP1R26 KIAA0649 Homo sapiens (Human) negative regulation of phosphatase activity [GO:0010923] nucleolus [GO:0005730] protein phosphatase inhibitor activity [GO:0004864] 0.96911 -4.7665 AAGGGSR 0 0 0 10.2097 10.1924 10.3184 0 0 0 0 0 0 0 0 8.19061 0 0 10.3156 0 0 10.1856 10.6916 0 10.6165 0 0 9.3718 Q5T8D3 ACBD5_HUMAN Acyl-CoA-binding domain-containing protein 5 ACBD5 KIAA1996 Homo sapiens (Human) autophagy of peroxisome [GO:0030242]; fatty acid metabolic process [GO:0006631] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777] fatty-acyl-CoA binding [GO:0000062] 0.80103 0.23932 GGETDEFSNVR 0 0 0 0 0 0 0 8.65567 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5T8I3 EEIG2_HUMAN EEIG family member 2 (EEIG2) EEIG2 FAM102B Homo sapiens (Human) 0.87663 -0.00080224 QDSVESQLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.81178 0 0 Q5T8I9 HENMT_HUMAN Small RNA 2'-O-methyltransferase (EC 2.1.1.386) (HEN1 methyltransferase homolog 1) HENMT1 C1orf59 Homo sapiens (Human) piRNA processing [GO:0034587]; RNA methylation [GO:0001510]; siRNA processing [GO:0030422] cytoplasm [GO:0005737]; nucleus [GO:0005634]; P granule [GO:0043186] metal ion binding [GO:0046872]; O-methyltransferase activity [GO:0008171]; RNA binding [GO:0003723]; RNA methyltransferase activity [GO:0008173]; small RNA 2'-O-methyltransferase activity [GO:0090486] 0.69555 0.37634 AKIENSPTPFCVGDK 0 0 0 10.831 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.76183 0 0 0 0 Q5T8P6 RBM26_HUMAN RNA-binding protein 26 (CTCL tumor antigen se70-2) (RNA-binding motif protein 26) RBM26 C13orf10 PRO1777 Homo sapiens (Human) mRNA processing [GO:0006397] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA binding [GO:0003723] 0.969 -7.5376 AASPGRCLPK 13.2311 12.8944 0 0 0 13.2479 0 10.5585 0 8.43538 9.15008 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5T9C9 PI5L1_HUMAN Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 (PI(4)P 5-kinase-like protein 1) (PtdIns(4)P-5-kinase-like protein 1) (EC 2.7.1.68) PIP5KL1 Homo sapiens (Human) negative regulation of cell migration [GO:0030336]; negative regulation of mitochondrial membrane potential [GO:0010917]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of apoptotic process [GO:0043065] cell projection [GO:0042995]; cytosol [GO:0005829]; membrane [GO:0016020] 1-phosphatidylinositol-4-phosphate 5-kinase activity [GO:0016308]; ATP binding [GO:0005524] 0.92405 -1.0353 AAPSPGPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.70586 8.80742 0 0 0 0 0 0 Q5T9L3 WLS_HUMAN Protein wntless homolog (Integral membrane protein GPR177) (Protein evenness interrupted homolog) (EVI) (Putative NF-kappa-B-activating protein 373) WLS C1orf139 GPR177 UNQ85/PRO18667 Homo sapiens (Human) anterior/posterior axis specification [GO:0009948]; cementum mineralization [GO:0071529]; exocrine pancreas development [GO:0031017]; hindbrain development [GO:0030902]; intracellular protein transport [GO:0006886]; mesoderm formation [GO:0001707]; midbrain development [GO:0030901]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of Wnt protein secretion [GO:0061357]; positive regulation of Wnt signaling pathway [GO:0030177]; Wnt protein secretion [GO:0061355]; Wnt signaling pathway [GO:0016055] cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endocytic vesicle membrane [GO:0030666]; endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802] identical protein binding [GO:0042802]; Wnt-protein binding [GO:0017147] 0.84296 0.15187 FYLLNIR 0 0 0 8.69648 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5T9S5 CCD18_HUMAN Coiled-coil domain-containing protein 18 (Sarcoma antigen NY-SAR-24) CCDC18 Homo sapiens (Human) centriolar satellite [GO:0034451]; cytoplasm [GO:0005737] 0.96974 -5.9282 EDRCIGCCEANK 0 9.39412 0 0 0 0 0 10.3422 10.3736 11.3133 0 0 9.48941 0 0 11.2572 10.7978 0 0 10.6993 10.1467 9.83494 0 0 0 0 0 Q5TAA0 TTC22_HUMAN Tetratricopeptide repeat protein 22 (TPR repeat protein 22) TTC22 Homo sapiens (Human) 0.81255 0.22406 LGQEEEEEACAAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.7921 0 0 0 9.22156 0 0 0 0 0 0 Q5TAP6 UT14C_HUMAN U3 small nucleolar RNA-associated protein 14 homolog C UTP14C KIAA0266 Homo sapiens (Human) cell differentiation [GO:0030154]; meiotic cell cycle [GO:0051321]; rRNA processing [GO:0006364]; spermatogenesis [GO:0007283] cytosol [GO:0005829]; nucleolus [GO:0005730]; small-subunit processome [GO:0032040] 0.80035 0.23951 AEDVGYQSSSR 0 0 0 0 0 0 0 0 0 0 8.22448 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5TAT6 CODA1_HUMAN Collagen alpha-1(XIII) chain (COLXIIIA1) COL13A1 Homo sapiens (Human) cell differentiation [GO:0030154]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; morphogenesis of a branching structure [GO:0001763]; skeletal system development [GO:0001501] cell-cell junction [GO:0005911]; collagen type XIII trimer [GO:0005600]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211] extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201] 0.91655 -0.76739 GKPGDMGPPGPQGPPGKDGPPGVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1439 0 0 Q5TAX3 TUT4_HUMAN Terminal uridylyltransferase 4 (TUTase 4) (EC 2.7.7.52) (Zinc finger CCHC domain-containing protein 11) TUT4 KIAA0191 ZCCHC11 Homo sapiens (Human) miRNA catabolic process [GO:0010587]; miRNA metabolic process [GO:0010586]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; oocyte maturation [GO:0001556]; polyuridylation-dependent mRNA catabolic process [GO:1990074]; pre-miRNA processing [GO:0031054]; retrotransposon silencing by mRNA destabilization [GO:0141008]; RNA 3' uridylation [GO:0071076]; RNA 3'-end processing [GO:0031123]; stem cell population maintenance [GO:0019827] cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleolus [GO:0005730] miRNA binding [GO:0035198]; RNA binding [GO:0003723]; RNA uridylyltransferase activity [GO:0050265]; zinc ion binding [GO:0008270] 0.95246 -1.4617 DLGLVLRDQSHCK 0 13.1077 0 11.224 10.851 10.7973 0 10.0307 8.50196 0 0 0 0 9.96867 0 10.6795 10.8011 10.8077 0 0 0 0 0 0 10.7969 0 0 Q5TB30 DEP1A_HUMAN DEP domain-containing protein 1A DEPDC1 DEPDC1A Homo sapiens (Human) intracellular signal transduction [GO:0035556]; negative regulation of DNA-templated transcription [GO:0045892] nucleus [GO:0005634]; transcription repressor complex [GO:0017053] GTPase activator activity [GO:0005096] 0.89911 -0.63849 EYPLIYQK 0 8.44547 0 0 0 0 0 8.82839 10.756 0 0 0 0 9.0847 0 0 0 0 13.1897 0 0 0 0 0 0 0 0 Q5TB80 CE162_HUMAN Centrosomal protein of 162 kDa (Cep162) (Protein QN1 homolog) CEP162 C6orf84 KIAA1009 QN1 Homo sapiens (Human) cilium assembly [GO:0060271] axonemal microtubule [GO:0005879]; centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; spindle [GO:0005819] 0.9688 -7.9224 ALEKELDDIK 9.13147 8.84219 8.80587 10.872 0 0 10.612 8.28757 0 9.87434 10.0751 10.1567 9.94084 0 0 0 0 0 0 0 10.8138 0 9.88425 9.56615 0 9.45457 0 Q5TBA9 FRY_HUMAN Protein furry homolog FRY C13orf14 Homo sapiens (Human) cell morphogenesis [GO:0000902]; negative regulation of tubulin deacetylation [GO:1904428]; neuron projection development [GO:0031175] cell cortex [GO:0005938]; microtubule organizing center [GO:0005815]; site of polarized growth [GO:0030427]; spindle pole [GO:0000922] enzyme inhibitor activity [GO:0004857] 0.89892 -0.65753 GVVPRDMPLNIFVK 0 0 9.58896 0 0 0 0 9.56908 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5TBB1 RNH2B_HUMAN Ribonuclease H2 subunit B (RNase H2 subunit B) (Aicardi-Goutieres syndrome 2 protein) (AGS2) (Deleted in lymphocytic leukemia 8) (Ribonuclease HI subunit B) RNASEH2B DLEU8 Homo sapiens (Human) fibroblast proliferation [GO:0048144]; gene expression [GO:0010467]; in utero embryonic development [GO:0001701]; mismatch repair [GO:0006298]; negative regulation of gene expression [GO:0010629]; positive regulation of fibroblast proliferation [GO:0048146]; regulation of DNA damage checkpoint [GO:2000001]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; ribonucleotide metabolic process [GO:0009259]; RNA catabolic process [GO:0006401] nucleoplasm [GO:0005654]; ribonuclease H2 complex [GO:0032299] 0.91565 -0.77195 LLHHVTEEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.01511 0 0 0 0 Q5TBK1 N42L1_HUMAN NEDD4-binding protein 2-like 1 N4BP2L1 CG081 Homo sapiens (Human) 0.91538 -0.81165 EDSFLQSFGR 0 0 0 0 0 0 0 0 0 10.1907 0 9.3289 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5TC63 GRTP1_HUMAN Growth hormone-regulated TBC protein 1 (TBC1 domain family member 6) GRTP1 TBC1D6 Homo sapiens (Human) activation of GTPase activity [GO:0090630] GTPase activator activity [GO:0005096] 0.92621 -1.1815 LEDAIRTDLNR 0 0 0 0 0 0 0 0 0 0 9.95418 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5TC79 ZBT37_HUMAN Zinc finger and BTB domain-containing protein 37 ZBTB37 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of cytokine production [GO:0001817]; regulation of immune system process [GO:0002682] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96798 -2.7832 EQEVSERWFR 0 0 0 0 0 0 0 0 0 0 0 11.0322 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5TC82 RC3H1_HUMAN Roquin-1 (Roquin) (EC 2.3.2.27) (RING finger and C3H zinc finger protein 1) (RING finger and CCCH-type zinc finger domain-containing protein 1) (RING finger protein 198) RC3H1 KIAA2025 RNF198 Homo sapiens (Human) "3'-UTR-mediated mRNA destabilization [GO:0061158]; B cell homeostasis [GO:0001782]; cellular response to interleukin-1 [GO:0071347]; lymph node development [GO:0048535]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of germinal center formation [GO:0002635]; negative regulation of T-helper 17 cell differentiation [GO:2000320]; negative regulation of T-helper cell differentiation [GO:0045623]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; P-body assembly [GO:0033962]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; post-transcriptional regulation of gene expression [GO:0010608]; protein polyubiquitination [GO:0000209]; regulation of germinal center formation [GO:0002634]; regulation of miRNA metabolic process [GO:2000628]; regulation of mRNA stability [GO:0043488]; regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900151]; regulation of T cell receptor signaling pathway [GO:0050856]; spleen development [GO:0048536]; T cell homeostasis [GO:0043029]; T cell proliferation [GO:0042098]; T cell receptor signaling pathway [GO:0050852]; T follicular helper cell differentiation [GO:0061470]; ubiquitin-dependent protein catabolic process [GO:0006511]" cytoplasmic stress granule [GO:0010494]; P-body [GO:0000932] CCR4-NOT complex binding [GO:1905762]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; RNA stem-loop binding [GO:0035613]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.88212 0.010202 VVNSQYGTQPQQYPPIYPSHYDGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4371 0 0 0 0 0 0 0 0 Q5TC84 OGRL1_HUMAN Opioid growth factor receptor-like protein 1 OGFRL1 Homo sapiens (Human) membrane [GO:0016020] opioid growth factor receptor activity [GO:0140625] 0.933 -1.2789 QSALEYFVYTIR 0 0 0 0 0 0 0 0 0 0 0 0 9.44135 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5TCH4 CP4AM_HUMAN Cytochrome P450 4A22 (CYPIVA22) (Fatty acid omega-hydroxylase) (Lauric acid omega-hydroxylase) (Long-chain fatty acid omega-monooxygenase) (EC 1.14.14.80) CYP4A22 Homo sapiens (Human) arachidonic acid metabolic process [GO:0019369]; icosanoid biosynthetic process [GO:0046456]; kidney development [GO:0001822]; lauric acid metabolic process [GO:0048252]; linoleic acid metabolic process [GO:0043651]; lipid hydroxylation [GO:0002933] endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231] 16-hydroxypalmitate dehydrogenase activity [GO:0103002]; alkane 1-monooxygenase activity [GO:0018685]; arachidonic acid monooxygenase activity [GO:0008391]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; long-chain fatty acid omega-hydroxylase activity [GO:0102033]; medium-chain fatty acid omega-hydroxylase activity [GO:0140981] 0.96973 -3.3056 AAQLYLHRQWLLK 0 0 0 0 0 0 0 0 0 0 0 8.99373 0 10.9753 0 0 11.4274 0 0 0 0 0 0 0 0 0 0 Q5TCQ9 MAGI3_HUMAN "Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (Membrane-associated guanylate kinase inverted 3) (MAGI-3)" MAGI3 KIAA1634 Homo sapiens (Human) apoptotic process [GO:0006915]; intracellular signal transduction [GO:0035556]; signal transduction [GO:0007165] bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; guanylate kinase activity [GO:0004385] 0.96954 -3.1805 DETLEPLPK 0 0 0 0 0 0 10.3147 0 10.7832 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5TCS8 KAD9_HUMAN Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2) AK9 AKD1 AKD2 C6orf199 C6orf224 Homo sapiens (Human) AMP phosphorylation [GO:0006756]; phosphorylation [GO:0016310] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; nucleoside monophosphate kinase activity [GO:0050145] 0.96926 -5.6863 EKLQKFLR 0 9.43734 0 0 9.58011 9.50857 0 9.50736 0 11.1679 11.3002 10.2525 0 0 0 0 10.3279 0 0 9.29092 0 9.47547 10.0749 0 0 9.45744 0 Q5TCX8 M3K21_HUMAN Mitogen-activated protein kinase kinase kinase 21 (EC 2.7.11.25) (Mitogen-activated protein kinase kinase kinase MLK4) (Mixed lineage kinase 4) MAP3K21 KIAA1804 MLK4 Homo sapiens (Human) protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] cytoplasm [GO:0005737] ATP binding [GO:0005524]; JUN kinase kinase kinase activity [GO:0004706]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310] 0.8296 0.20758 EIDVLER 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3515 0 0 0 11.086 0 0 0 0 0 0 0 0 0 Q5TCY1 TTBK1_HUMAN Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase) TTBK1 BDTK KIAA1855 Homo sapiens (Human) learning or memory [GO:0007611]; negative regulation of gene expression [GO:0010629]; negative regulation of protein binding [GO:0032091]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of astrocyte activation [GO:0061890]; positive regulation of cyclin-dependent protein kinase activity [GO:1904031]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of gene expression [GO:0010628]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of protein polymerization [GO:0032273]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]; substantia nigra development [GO:0021762] cytosol [GO:0005829]; microtubule associated complex [GO:0005875]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321] 0.54738 0.57204 AVPLSLPYQDFK 0 11.8988 10.9037 0 12.0547 11.8874 0 0 0 13.9316 14.0245 13.7732 10.3484 0 0 9.60971 12.3289 12.0987 10.3774 0 0 9.40299 0 8.7095 10.6342 12.1925 12.3022 Q5TCZ1 SPD2A_HUMAN SH3 and PX domain-containing protein 2A (Adapter protein TKS5) (Five SH3 domain-containing protein) (SH3 multiple domains protein 1) (Tyrosine kinase substrate with five SH3 domains) SH3PXD2A FISH KIAA0418 SH3MD1 TKS5 Homo sapiens (Human) in utero embryonic development [GO:0001701]; osteoclast fusion [GO:0072675]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801] anchoring junction [GO:0070161]; cell projection [GO:0042995]; cytosol [GO:0005829]; podosome [GO:0002102] "phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protease binding [GO:0002020]; superoxide-generating NADPH oxidase activator activity [GO:0016176]" 0.96758 -2.8163 EGWAPASYLKK 0 0 10.9025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5TDH0 DDI2_HUMAN Protein DDI1 homolog 2 (EC 3.4.23.-) DDI2 Homo sapiens (Human) cellular response to hydroxyurea [GO:0072711]; proteasomal protein catabolic process [GO:0010498]; protein processing [GO:0016485]; regulation of DNA stability [GO:0097752]; regulation of protein stability [GO:0031647] chromosome [GO:0005694]; cytosol [GO:0005829]; nucleoplasm [GO:0005654] aspartic-type endopeptidase activity [GO:0004190]; identical protein binding [GO:0042802]; ubiquitin binding [GO:0043130] 0.92161 -1.1088 HQCSIDLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.02503 0 0 0 0 0 0 0 0 0 0 0 Q5TDP6 LGSN_HUMAN Lengsin (Glutamate-ammonia ligase domain-containing protein 1) (Lens glutamine synthase-like) LGSN GLULD1 LGS Homo sapiens (Human) nitrogen compound metabolic process [GO:0006807] cytoplasm [GO:0005737]; membrane [GO:0016020]; plasma membrane [GO:0005886] catalytic activity [GO:0003824] 0.92291 -1.0786 TGVKEVARK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2189 0 0 0 9.44232 0 0 0 0 0 Q5TEA3 DAAF9_HUMAN Dynein axonemal assembly factor 9 (DNAAF9) DNAAF9 C20orf194 Homo sapiens (Human) 0.58512 0.46567 IVPLDSEDSLSFVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6304 0 0 0 0 0 9.36606 Q5TEA6 SE1L2_HUMAN Protein sel-1 homolog 2 (Suppressor of lin-12-like protein 2) (Sel-1L2) SEL1L2 C20orf50 Homo sapiens (Human) ERAD pathway [GO:0036503] endoplasmic reticulum membrane [GO:0005789] 0.95483 -1.6071 DILFFNFTTR 9.65388 0 0 0 0 0 0 0 0 0 0 10.6004 0 0 0 0 0 0 0 0 0 0 9.48985 0 0 0 0 Q5TEC3 ZN697_HUMAN Zinc finger protein 697 ZNF697 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96207 -2.6246 EGDPEER 0 0 0 0 0 0 0 0 0 9.2132 9.22632 9.15793 0 8.62165 0 0 0 0 0 0 0 0 0 0 10.2242 9.27736 0 Q5TEZ5 CF163_HUMAN Uncharacterized protein C6orf163 C6orf163 Homo sapiens (Human) 0.92325 -1.1526 IIPPAPFGKTFKR 0 0 0 0 0 9.94575 9.49572 0 9.69942 0 0 0 9.44754 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5TF21 SOGA3_HUMAN Protein SOGA3 SOGA3 C6orf174 Homo sapiens (Human) regulation of autophagy [GO:0010506] extracellular space [GO:0005615]; membrane [GO:0016020] 0.9677 -2.7462 DIRSEAER 9.57609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.35753 11.3069 0 0 0 0 0 0 Q5TG30 RHG40_HUMAN Rho GTPase-activating protein 40 (Rho-type GTPase-activating protein 40) ARHGAP40 C20orf95 Homo sapiens (Human) regulation of actin filament polymerization [GO:0030833]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829] GTPase activator activity [GO:0005096] 0.87917 0.0048237 DKAGDGLEATPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.8875 0 0 0 0 0 0 0 0 Q5TGL8 PXDC1_HUMAN PX domain-containing protein 1 PXDC1 C6orf145 Homo sapiens (Human) phosphatidylinositol binding [GO:0035091] 0.82063 0.21952 TIISMPCK 10.1262 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5TGP6 MROH9_HUMAN Maestro heat-like repeat-containing protein family member 9 MROH9 C1orf129 Homo sapiens (Human) 0.16415 0.99226 CQNDIGTNKPTNGK 0 0 0 0 0 0 0 0 0 0 0 0 9.23376 0 0 0 0 0 0 0 0 0 0 0 0 0 9.53737 Q5TGU0 TSPO2_HUMAN Translocator protein 2 (Peripheral-type benzodiazepine receptor-like protein 1) TSPO2 BZRPL1 Homo sapiens (Human) 5-aminolevulinic acid import across plasma membrane [GO:0140484]; enucleate erythrocyte differentiation [GO:0043353]; import across plasma membrane [GO:0098739]; intracellular cholesterol transport [GO:0032367]; lipid droplet organization [GO:0034389] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; organelle membrane [GO:0031090]; plasma membrane [GO:0005886] 5-aminolevulinic acid transmembrane transporter activity [GO:0140485]; cholesterol binding [GO:0015485] 0.80947 0.22658 MLSWCPFYK 0 0 0 0 0 0 0 0 0 8.70943 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5TGY1 TMCO4_HUMAN Transmembrane and coiled-coil domain-containing protein 4 TMCO4 Homo sapiens (Human) membrane [GO:0016020] 0.82037 0.2188 MAMWNRPCQR 0 10.1401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5TGY3 AHDC1_HUMAN Transcription factor Gibbin (AT-hook DNA-binding motif-containing protein 1) AHDC1 Homo sapiens (Human) cell differentiation [GO:0030154]; mesoderm formation [GO:0001707]; skin morphogenesis [GO:0043589] chromosome [GO:0005694]; nucleus [GO:0005634] DNA-binding transcription factor activity [GO:0003700]; promoter-enhancer loop anchoring activity [GO:0140585] 0.33461 0.77449 AGGFGGR 11.1525 11.0999 11.0415 0 11.0551 11.0507 11.4364 11.1051 9.46614 0 0 0 0 0 0 0 0 0 0 0 0 9.56071 8.89439 0 0 0 0 Q5TH69 BIG3_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF family member 3) ARFGEF3 BIG3 C6orf92 KIAA1244 Homo sapiens (Human) regulation of ARF protein signal transduction [GO:0032012] Golgi apparatus [GO:0005794]; transport vesicle membrane [GO:0030658] guanyl-nucleotide exchange factor activity [GO:0005085] 0.88198 -0.099285 EFDTSPGLK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.58918 0 0 0 0 0 0 0 0 0 0 0 9.1553 0 Q5THJ4 VP13D_HUMAN Intermembrane lipid transfer protein VPS13D (Vacuolar protein sorting-associated protein 13D) VPS13D KIAA0453 Homo sapiens (Human) lipid transport [GO:0006869]; mitochondrion organization [GO:0007005]; positive regulation of mitophagy [GO:1901526]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898] 0.96992 -4.1388 ALLQALEEKWKNDR 0 10.908 10.0051 9.258 9.03546 9.28091 0 10.8643 0 0 12.8932 0 0 0 9.45976 10.2663 0 0 0 10.0737 0 0 0 0 9.69763 9.96511 0 Q5THK1 PR14L_HUMAN Protein PRR14L (Proline rich 14-like protein) PRR14L C22orf30 Homo sapiens (Human) 0.8848 -0.24825 ASNLLDCGAR 0 0 0 0 0 11.6749 0 0 0 0 0 10.4175 0 0 0 11.541 0 10.0642 0 0 0 0 0 0 0 0 0 Q5THR3 EFCB6_HUMAN EF-hand calcium-binding domain-containing protein 6 (CAP-binding protein complex-interacting protein 1) (DJ-1-binding protein) (DJBP) EFCAB6 DJBP KIAA1672 Homo sapiens (Human) cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; nucleoplasm [GO:0005654] calcium ion binding [GO:0005509] 0.96914 -6.7983 AVENSKSTGAQPK 0 0 13.0077 0 0 0 0 0 0 0 0 0 0 0 10.388 11.6862 11.0044 0 0 0 9.87573 0 0 9.84444 0 10.0747 12.0047 Q5TID7 CC181_HUMAN Coiled-coil domain-containing protein 181 CCDC181 C1orf114 Homo sapiens (Human) cytoplasm [GO:0005737]; manchette [GO:0002177]; microtubule [GO:0005874]; sperm flagellum [GO:0036126] microtubule binding [GO:0008017] 0.94625 -1.3449 DLEWLINENEK 0 0 0 0 0 0 0 0 0 0 0 10.3982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5TKA1 LIN9_HUMAN Protein lin-9 homolog (HuLin-9) (hLin-9) (Beta subunit-associated regulator of apoptosis) (TUDOR gene similar protein) (Type I interferon receptor beta chain-associated protein) (pRB-associated protein) LIN9 BARA TGS Homo sapiens (Human) cell cycle [GO:0007049]; DNA biosynthetic process [GO:0071897]; DNA-templated transcription [GO:0006351]; regulation of cell cycle [GO:0051726]; regulation of transcription by RNA polymerase II [GO:0006357]; reproduction [GO:0000003] nucleoplasm [GO:0005654]; transcription repressor complex [GO:0017053] DNA binding [GO:0003677] 0.96719 -2.8067 LREMNTEAEK 0 0 0 0 0 0 0 0 0 0 10.8119 0 0 0 0 0 0 9.48999 0 0 0 0 0 0 0 0 0 Q5TYW1 ZN658_HUMAN Zinc finger protein 658 ZNF658 Homo sapiens (Human) cellular response to zinc ion [GO:0071294]; negative regulation of DNA-templated transcription [GO:0045892]; ribosome biogenesis [GO:0042254] nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; transcription cis-regulatory region binding [GO:0000976]" 0.96165 -2.4548 EEWQHLGPVER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.21522 0 0 0 0 0 0 10.1727 Q5TZA2 CROCC_HUMAN Rootletin (Ciliary rootlet coiled-coil protein) CROCC KIAA0445 Homo sapiens (Human) cellular homeostasis [GO:0019725]; centriole-centriole cohesion [GO:0010457]; centrosome cycle [GO:0007098]; ciliary basal body organization [GO:0032053]; epithelial structure maintenance [GO:0010669]; establishment of localization in cell [GO:0051649]; establishment of organelle localization [GO:0051656]; photoreceptor cell maintenance [GO:0045494]; positive regulation of cilium assembly [GO:0045724]; positive regulation of protein localization to cilium [GO:1903566]; protein localization [GO:0008104]; protein localization to organelle [GO:0033365] 9+2 motile cilium [GO:0097729]; actin cytoskeleton [GO:0015629]; centriole [GO:0005814]; centrosome [GO:0005813]; ciliary rootlet [GO:0035253]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; subapical part of cell [GO:0120219] actin binding [GO:0003779]; kinesin binding [GO:0019894]; structural constituent of cytoskeleton [GO:0005200]; structural molecule activity [GO:0005198] 0.96853 -10.037 ALEEQLQRLR 0 9.20146 0 0 0 0 0 0 9.24968 0 0 0 0 0 10.3829 10.9402 10.0816 0 11.453 9.55244 0 9.7623 9.99986 9.12135 0 0 0 Q5U3C3 TM164_HUMAN Transmembrane protein 164 TMEM164 Homo sapiens (Human) positive regulation of ferroptosis [GO:0160020] membrane [GO:0016020] 0.91407 -0.78134 LPAKKID 0 0 0 0 0 0 0 0 0 0 8.99325 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5U4N7 GDAS1_HUMAN "Protein GDF5-AS1, mitochondrial (GDF5 antisense RNA 1) (Growth/differentiation factor 5 opposite strand transcript protein)" GDF5-AS1 GDF5OS Homo sapiens (Human) mitochondrion [GO:0005739] 0.96181 -2.5581 FLVRPNTR 0 0 0 0 0 0 0 0 10.1158 0 0 0 0 0 0 0 9.2833 0 0 0 0 0 0 0 0 0 0 Q5U4P2 ASPH1_HUMAN Aspartate beta-hydroxylase domain-containing protein 1 (EC 1.14.11.-) ASPHD1 Homo sapiens (Human) peptidyl-amino acid modification [GO:0018193] membrane [GO:0016020] dioxygenase activity [GO:0051213] 0.96182 -2.5882 GSFSVER 0 0 0 10.0171 0 10.04 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5U5R9 HECD2_HUMAN Probable E3 ubiquitin-protein ligase HECTD2 (EC 2.3.2.26) (HECT domain-containing protein 2) (HECT-type E3 ubiquitin transferase HECTD2) HECTD2 Homo sapiens (Human) protein polyubiquitination [GO:0000209] cytosol [GO:0005829] ubiquitin protein ligase activity [GO:0061630] 0.96789 -2.7833 DFQEDVEK 0 0 8.76421 0 0 0 0 0 0 0 0 0 10.625 0 0 0 10.9287 0 0 0 0 0 0 0 0 0 0 Q5U5X8 F222A_HUMAN Protein FAM222A FAM222A C12orf34 Homo sapiens (Human) 0.81793 0.21995 CEAVASAMHSSR 0 0 0 0 0 0 0 0 0 0 0 8.60025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5U5Z8 CBPC2_HUMAN Cytosolic carboxypeptidase 2 (EC 3.4.17.-) (ATP/GTP-binding protein-like 2) (Protein deglutamylase CCP2) AGBL2 CCP2 Homo sapiens (Human) protein side chain deglutamylation [GO:0035610]; proteolysis [GO:0006508] centriole [GO:0005814]; ciliary basal body [GO:0036064]; cytosol [GO:0005829] metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270] 0.91687 -0.86079 GCAAMAAYPSLHIYTYP 0 0 0 9.47257 0 0 0 9.90168 0 0 0 10.1307 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5U623 MCAF2_HUMAN Activating transcription factor 7-interacting protein 2 (ATF7-interacting protein 2) (MBD1-containing chromatin-associated factor 2) ATF7IP2 MCAF2 Homo sapiens (Human) positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309]; regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634]; transcription regulator complex [GO:0005667] transcription coregulator activity [GO:0003712] 0.87414 0.031673 SIPGFSENLT 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6757 0 0 Q5U649 CL060_HUMAN Uncharacterized protein C12orf60 C12orf60 Homo sapiens (Human) 0.95444 -1.5022 TEDSKNPTK 0 0 0 0 0 0 0 0 0 10.3774 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5UAW9 GP157_HUMAN G-protein coupled receptor 157 GPR157 Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; circadian behavior [GO:0048512]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; radial glial cell differentiation [GO:0060019] ciliary membrane [GO:0060170]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930] 0.6129 0.42039 SPAGTPK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.19387 0 0 0 0 0 0 8.88197 0 0 9.86859 0 0 0 Q5UE93 PI3R6_HUMAN Phosphoinositide 3-kinase regulatory subunit 6 (Phosphoinositide 3-kinase gamma adapter protein of 87 kDa) (p84 PI3K adapter protein) (p84 PIKAP) (p87 PI3K adapter protein) (p87PIKAP) PIK3R6 C17orf38 Homo sapiens (Human) angiogenesis [GO:0001525]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; positive regulation of angiogenesis [GO:0045766]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of T cell differentiation [GO:0045582]; regulation of natural killer cell mediated cytotoxicity [GO:0042269] "cytosol [GO:0005829]; membrane [GO:0016020]; phosphatidylinositol 3-kinase complex [GO:0005942]; phosphatidylinositol 3-kinase complex, class IA [GO:0005943]; phosphatidylinositol 3-kinase complex, class IB [GO:0005944]; plasma membrane [GO:0005886]" "1-phosphatidylinositol-3-kinase regulator activity [GO:0046935]; phosphatidylinositol-4,5-bisphosphate 3-kinase activity [GO:0046934]" 0.84207 0.14503 ATGITEELYQR 0 0 12.6404 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5UIP0 RIF1_HUMAN Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) RIF1 Homo sapiens (Human) "cell cycle [GO:0007049]; cellular response to leukemia inhibitory factor [GO:1990830]; DNA damage response [GO:0006974]; DNA repair [GO:0006281]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; positive regulation of histone H3-K9 methylation [GO:0051574]; positive regulation of isotype switching [GO:0045830]; somatic stem cell population maintenance [GO:0035019]; subtelomeric heterochromatin formation [GO:0031509]; telomere maintenance [GO:0000723]; telomere maintenance in response to DNA damage [GO:0043247]" "chromatin [GO:0000785]; chromosome, telomeric repeat region [GO:0140445]; condensed chromosome [GO:0000793]; cytoplasm [GO:0005737]; female pronucleus [GO:0001939]; male pronucleus [GO:0001940]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of double-strand break [GO:0035861]; spindle midzone [GO:0051233]" 0.9693 -3.1915 ENTMQESLPSGIVNFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1935 0 0 0 0 10.0218 10.1844 0 0 0 0 Q5VIR6 VPS53_HUMAN Vacuolar protein sorting-associated protein 53 homolog VPS53 PP13624 Homo sapiens (Human) "endocytic recycling [GO:0032456]; lysosomal transport [GO:0007041]; protein targeting to lysosome [GO:0006622]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle-mediated cholesterol transport [GO:0090119]" cytosol [GO:0005829]; EARP complex [GO:1990745]; endosome membrane [GO:0010008]; GARP complex [GO:0000938]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; trans-Golgi network membrane [GO:0032588] 0.96424 -2.2702 DKAEKSEQMVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.16118 0 0 0 0 0 0 0 0 0 11.686 11.863 Q5VIY5 ZN468_HUMAN Zinc finger protein 468 ZNF468 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.89036 -0.49679 EKSFECIQSFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1648 10.54 10.4614 0 0 0 0 10.1021 0 10.584 10.3067 10.1787 Q5VSD8 YI029_HUMAN Putative uncharacterized protein LOC401522 Homo sapiens (Human) 0.88351 -0.069612 GLLGCVGSGHCPLPTPAQFPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8417 0 0 0 0 Q5VST9 OBSCN_HUMAN Obscurin (EC 2.7.11.1) (Obscurin-RhoGEF) (Obscurin-myosin light chain kinase) (Obscurin-MLCK) OBSCN KIAA1556 KIAA1639 Homo sapiens (Human) protein localization to M-band [GO:0036309]; protein phosphorylation [GO:0006468]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214] cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018] "ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; guanyl-nucleotide exchange factor activity [GO:0005085]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]" 0.96844 -9.7751 ASSLKVSTSARLEVR 8.41193 0 8.66558 0 0 0 10.9028 8.74315 0 0 11.345 0 0 12.0594 0 9.40216 0 0 12.1136 0 11.2502 0 12.6316 10.6874 10.7525 0 10.7439 Q5VT03 NTM2D_HUMAN NUT family member 2D NUTM2D FAM22D Homo sapiens (Human) 0.67065 0.39371 LDSSSSK 0 0 0 0 0 0 0 0 0 0 8.67175 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5VT06 CE350_HUMAN Centrosome-associated protein 350 (Cep350) (Centrosome-associated protein of 350 kDa) CEP350 CAP350 KIAA0480 GM133 Homo sapiens (Human) microtubule anchoring [GO:0034453]; non-motile cilium assembly [GO:1905515]; protein localization to centrosome [GO:0071539] cell projection [GO:0042995]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleus [GO:0005634]; spindle [GO:0005819] microtubule binding [GO:0008017] 0.8905 -0.4683 FTMEMVR 10.214 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.214 10.1435 0 0 12.2349 Q5VT25 MRCKA_HUMAN Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (DMPK-like alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha) CDC42BPA KIAA0451 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; actomyosin structure organization [GO:0031032]; cell migration [GO:0016477]; peptidyl-threonine phosphorylation [GO:0018107]; protein phosphorylation [GO:0006468] actomyosin [GO:0042641]; cell leading edge [GO:0031252]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lamellipodium [GO:0030027] ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96924 -6.5454 GIGTAYEGHVR 0 9.35975 9.27188 0 0 0 9.67918 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.79858 0 0 0 0 Q5VT33 CX031_HUMAN Putative uncharacterized protein encoded by LINC01545 LINC01545 CXorf31 Homo sapiens (Human) 0.94836 -1.3641 LIPEHWEKWEDVKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.526 0 0 Q5VT40 FA78B_HUMAN Protein FAM78B FAM78B Homo sapiens (Human) 0.92224 -1.1203 EKIILQTIKWR 0 0 0 0 0 0 0 9.52105 9.59626 9.3256 9.54346 9.54537 0 0 0 0 8.94843 0 0 0 0 0 0 0 0 0 10.3828 Q5VT79 AXA81_HUMAN Annexin A8-like protein 1 ANXA8L1 ANXA8L2 Homo sapiens (Human) endosomal transport [GO:0016197]; endosome organization [GO:0007032]; negative regulation of phospholipase A2 activity [GO:1900138]; negative regulation of serine-type endopeptidase activity [GO:1900004] cytoplasm [GO:0005737] calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544] 0.79939 0.23975 EGVIIEILASR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.123 0 0 0 0 0 Q5VT97 SYDE2_HUMAN Rho GTPase-activating protein SYDE2 (Synapse defective protein 1 homolog 2) (Protein syd-1 homolog 2) SYDE2 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; cell migration [GO:0016477]; regulation of Ras protein signal transduction [GO:0046578]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] cytosol [GO:0005829]; synaptic membrane [GO:0097060] GTPase activator activity [GO:0005096] 0.91636 -0.83869 DLQESIDTLIGNLER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.73439 0 0 0 0 8.487 0 0 0 0 0 0 0 Q5VT98 PRA20_HUMAN PRAME family member 20 PRAMEF20 PRAMEF21 Homo sapiens (Human) negative regulation of apoptotic process [GO:0043066]; negative regulation of cell differentiation [GO:0045596]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of cell population proliferation [GO:0008284] cytoplasm [GO:0005737] 0.879 0.011633 LVLSDIDSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.66274 0 0 0 0 0 0 Q5VTA0 PRA17_HUMAN PRAME family member 17 PRAMEF17 Homo sapiens (Human) negative regulation of apoptotic process [GO:0043066]; negative regulation of cell differentiation [GO:0045596]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of cell population proliferation [GO:0008284] cytoplasm [GO:0005737] 0.76355 0.29669 QTVEDYPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.93232 0 0 Q5VTB9 RN220_HUMAN E3 ubiquitin-protein ligase RNF220 (EC 2.3.2.27) (RING finger protein 220) (RING-type E3 ubiquitin transferase RNF220) RNF220 C1orf164 Homo sapiens (Human) dorsal/ventral neural tube patterning [GO:0021904]; noradrenergic neuron development [GO:0003358]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; protein autoubiquitination [GO:0051865]; protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]; regulation of transcription regulatory region DNA binding [GO:2000677] cytoplasm [GO:0005737]; nuclear lamina [GO:0005652]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] beta-catenin binding [GO:0008013]; metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.96312 -2.1889 DLHRAAFK 0 10.8379 0 0 0 0 10.712 0 0 9.76739 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5VTH2 FLTOP_HUMAN Protein Flattop (Cilia- and flagella-associated protein 126) CFAP126 C1orf192 FLTP Homo sapiens (Human) cilium organization [GO:0044782] apical plasma membrane [GO:0016324]; axonemal microtubule [GO:0005879]; ciliary basal body [GO:0036064]; cilium [GO:0005929] 0.86765 0.071523 YLQNWSPTKPTK 0 0 0 0 9.51981 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5VTH9 DNAI4_HUMAN Dynein axonemal intermediate chain 4 (WD repeat-containing protein 78) DNAI4 WDR78 Homo sapiens (Human) axonemal dynein complex assembly [GO:0070286]; cilium movement [GO:0003341]; hematopoietic progenitor cell differentiation [GO:0002244] axonemal dynein complex [GO:0005858]; axoneme [GO:0005930]; dynein axonemal particle [GO:0120293]; motile cilium [GO:0031514] dynein heavy chain binding [GO:0045504]; dynein light chain binding [GO:0045503] 0.29947 0.8114 GTTGDGK 0 0 0 0 0 0 0 0 0 0 0 9.49731 0 0 0 0 11.1286 0 10.5386 0 9.64683 0 0 0 0 11.6165 0 Q5VTL7 FNDC7_HUMAN Fibronectin type III domain-containing protein 7 FNDC7 Homo sapiens (Human) extracellular region [GO:0005576] 0.84424 0.13696 AYAWNANR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.8631 0 0 0 0 0 0 0 0 Q5VTL8 PR38B_HUMAN Pre-mRNA-splicing factor 38B (Sarcoma antigen NY-SAR-27) PRPF38B Homo sapiens (Human) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] precatalytic spliceosome [GO:0071011] RNA binding [GO:0003723] 0.5721 0.48073 TAGQTGMCGGVR 0 10.1126 0 10.3792 0 10.295 10.633 10.7593 0 0 11.1857 0 0 0 0 0 0 0 0 0 0 0 0 0 10.204 0 0 Q5VTR2 BRE1A_HUMAN E3 ubiquitin-protein ligase BRE1A (BRE1-A) (hBRE1) (EC 2.3.2.27) (RING finger protein 20) (RING-type E3 ubiquitin transferase BRE1A) RNF20 BRE1A Homo sapiens (Human) histone H2B conserved C-terminal lysine ubiquitination [GO:0071894]; histone monoubiquitination [GO:0010390]; negative regulation of cell migration [GO:0030336]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]; regulation of DNA-templated transcription [GO:0006355]; ubiquitin-dependent protein catabolic process [GO:0006511] HULC complex [GO:0033503]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151] chromatin binding [GO:0003682]; histone binding [GO:0042393]; histone H2B C-terminal K residue ubiquitin ligase activity [GO:0140850]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; transcription coactivator activity [GO:0003713]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842] 0.96895 -6.6317 AELEDLRQR 0 0 0 0 0 0 0 0 0 0 0 9.62104 0 0 8.91663 0 0 0 9.80726 11.827 0 0 0 0 0 0 0 Q5VTT5 MYOM3_HUMAN Myomesin-3 (Myomesin family member 3) MYOM3 Homo sapiens (Human) M band [GO:0031430] protein homodimerization activity [GO:0042803] 0.14777 1.0233 EIFSSPNR 12.6686 0 0 0 0 0 0 0 0 0 0 0 10.4555 0 0 0 0 10.2511 0 0 0 0 0 0 0 0 0 Q5VU36 S31A5_HUMAN Spermatogenesis-associated protein 31A5 (Protein FAM75A5) SPATA31A5 FAM75A5 Homo sapiens (Human) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] membrane [GO:0016020] 0.96951 -4.0608 IQESLDLMQLR 0 0 0 0 0 0 0 8.85343 0 9.52597 0 0 0 0 0 0 0 0 0 10.5862 0 0 8.98442 0 0 0 0 Q5VU43 MYOME_HUMAN Myomegalin (Cardiomyopathy-associated protein 2) (Phosphodiesterase 4D-interacting protein) PDE4DIP CMYA2 KIAA0454 KIAA0477 MMGL Homo sapiens (Human) astral microtubule organization [GO:0030953]; centrosome cycle [GO:0007098]; positive regulation of microtubule nucleation [GO:0090063]; protein-containing complex assembly [GO:0065003]; regulation of Golgi organization [GO:1903358] centrosome [GO:0005813]; cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; myofibril [GO:0030016]; nucleus [GO:0005634] enzyme binding [GO:0019899]; molecular adaptor activity [GO:0060090] 0.8851 -0.23602 AESNSNPISLPTPQNTPK 10.189 0 0 0 9.28817 0 0 12.3975 0 0 9.31836 0 12.5811 0 0 0 0 0 0 0 0 10.1542 10.2868 9.09022 0 0 8.56837 Q5VU57 CBPC6_HUMAN Cytosolic carboxypeptidase 6 (EC 3.4.17.24) (ATP/GTP-binding protein-like 4) (Protein deglutamylase CCP6) AGBL4 CCP6 Homo sapiens (Human) anterograde axonal transport of mitochondrion [GO:0098957]; C-terminal protein deglutamylation [GO:0035609]; central nervous system neuron development [GO:0021954]; defense response to virus [GO:0051607]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein deglutamylation [GO:0035608]; protein side chain deglutamylation [GO:0035610]; proteolysis [GO:0006508]; regulation of blastocyst development [GO:0120222]; retrograde axonal transport of mitochondrion [GO:0098958] axon cytoplasm [GO:1904115]; centriole [GO:0005814]; ciliary basal body [GO:0036064]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794] metallocarboxypeptidase activity [GO:0004181]; tubulin binding [GO:0015631]; zinc ion binding [GO:0008270] 0.87338 0.036426 CSLMGFDLNR 0 0 0 0 0 0 0 0 0 0 0 9.0634 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5VU97 CAHD1_HUMAN VWFA and cache domain-containing protein 1 (Cache domain-containing protein 1) CACHD1 KIAA1573 VWCD1 Homo sapiens (Human) voltage-gated calcium channel complex [GO:0005891] voltage-gated calcium channel activity [GO:0005245] 0.77218 0.27168 NLNTVPSSK 0 0 0 0 0 7.93852 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5VUA4 ZN318_HUMAN Zinc finger protein 318 (Endocrine regulatory protein) ZNF318 HRIHFB2436 Homo sapiens (Human) meiotic cell cycle [GO:0051321]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of DNA-templated transcription [GO:0045893] cytosol [GO:0005829]; nucleoplasm [GO:0005654] nucleic acid binding [GO:0003676]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270] 0.96867 -8.147 EDGKTEAGK 0 11.2042 0 10.5055 0 0 0 0 11.1318 0 0 0 0 0 0 0 0 0 10.4739 0 0 0 0 9.44896 0 0 0 Q5VUB5 F1711_HUMAN Protein FAM171A1 (Astroprincin) (APCN) FAM171A1 APCN C10orf38 Homo sapiens (Human) regulation of cell shape [GO:0008360]; stress fiber assembly [GO:0043149] plasma membrane [GO:0005886] 0.84187 0.14277 LTIQEHLYPAPSSPEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.864 0 0 0 0 0 0 0 0 Q5VUG0 SMBT2_HUMAN Scm-like with four MBT domains protein 2 (Scm-like with 4 MBT domains protein 2) SFMBT2 KIAA1617 Homo sapiens (Human) negative regulation of gene expression [GO:0010629] aggresome [GO:0016235]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nuclear body [GO:0016604]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] histone binding [GO:0042393]; transcription corepressor activity [GO:0003714] 0.94753 -1.3483 RGRGAPAASSAEEGEK 11.4001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5VUJ6 LRCH2_HUMAN Leucine-rich repeat and calponin homology domain-containing protein 2 LRCH2 KIAA1495 Homo sapiens (Human) 0.92342 -1.0366 LVSIPEEIGK 0 0 0 0 0 8.47683 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3023 0 0 0 0 0 0 0 Q5VUJ9 DRC8_HUMAN Dynein regulatory complex protein 8 (EF-hand calcium-binding domain-containing protein 2) EFCAB2 DRC8 Homo sapiens (Human) cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; sperm principal piece [GO:0097228] calcium ion binding [GO:0005509] 0.41499 0.68653 AFEVLDSAK 11.5464 11.4862 11.4341 10.5837 0 11.5988 10.9791 10.9427 11.3036 14.227 14.1882 13.6847 0 9.43454 0 9.82804 0 10.6573 0 0 0 0 0 0 0 0 0 Q5VUY0 ADCL3_HUMAN Arylacetamide deacetylase-like 3 (EC 3.1.1.-) AADACL3 Homo sapiens (Human) membrane [GO:0016020] carboxylic ester hydrolase activity [GO:0052689] 0.84756 0.12683 LCKESDSVVLAVGYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.45175 0 0 0 9.44601 0 0 0 0 0 Q5VUY2 ADCL4_HUMAN Arylacetamide deacetylase-like 4 (EC 3.1.1.-) AADACL4 Homo sapiens (Human) membrane [GO:0016020] carboxylic ester hydrolase activity [GO:0052689] 0.18454 0.94596 ALETYGVDPSR 0 0 0 0 0 0 0 0 0 0 0 0 9.27903 9.2593 0 0 9.89949 0 0 0 0 10.2501 0 0 0 0 0 Q5VV17 OTUD1_HUMAN OTU domain-containing protein 1 (EC 3.4.19.12) (DUBA-7) OTUD1 DUBA7 OTDC1 Homo sapiens (Human) protein K63-linked deubiquitination [GO:0070536] cysteine-type deubiquitinase activity [GO:0004843] 0.96155 -2.5603 QALAAAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.0065 0 0 0 Q5VV41 ARHGG_HUMAN Rho guanine nucleotide exchange factor 16 (Ephexin-4) ARHGEF16 EPHEXIN4 NBR Homo sapiens (Human) activation of GTPase activity [GO:0090630]; cell chemotaxis [GO:0060326]; positive regulation of protein localization to plasma membrane [GO:1903078] cytosol [GO:0005829] cadherin binding [GO:0045296]; guanyl-nucleotide exchange factor activity [GO:0005085]; PDZ domain binding [GO:0030165]; receptor tyrosine kinase binding [GO:0030971]; small GTPase binding [GO:0031267] 0.9645 -2.6873 EALREIER 0 0 0 0 0 0 0 0 0 0 0 0 0 8.48748 0 0 0 0 0 0 0 0 0 0 0 9.49637 10.6079 Q5VV43 K0319_HUMAN Dyslexia-associated protein KIAA0319 KIAA0319 Homo sapiens (Human) multicellular organismal response to stress [GO:0033555]; negative regulation of axon extension [GO:0030517]; negative regulation of axon extension involved in regeneration [GO:0048692]; negative regulation of dendrite development [GO:2000171]; neuron migration [GO:0001764]; positive regulation of SMAD protein signal transduction [GO:0060391]; response to auditory stimulus [GO:0010996] clathrin-coated endocytic vesicle membrane [GO:0030669]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886] 0.75708 0.30459 HVLVLPNNSITLDGSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.378 0 0 0 0 0 0 0 0 0 Q5VV52 ZN691_HUMAN Zinc finger protein 691 ZNF691 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.87151 0.06097 VDDSEGSWIPPGEK 0 0 0 0 0 0 0 0 0 10.9646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5VV63 ATRN1_HUMAN Attractin-like protein 1 ATRNL1 KIAA0534 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186] membrane [GO:0016020] carbohydrate binding [GO:0030246]; Notch binding [GO:0005112] 0.9698 -5.1009 AFRDEELCK 0 0 0 0 0 0 0 0 0 9.32524 10.4283 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5VV67 PPRC1_HUMAN Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 (PGC-1-related coactivator) (PRC) PPRC1 KIAA0595 Homo sapiens (Human) positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription by RNA polymerase II [GO:0045944] nucleoplasm [GO:0005654]; nucleus [GO:0005634] nuclear receptor coactivator activity [GO:0030374]; RNA binding [GO:0003723] 0.96294 -2.5255 EGPLDLYPK 0 0 0 0 0 0 0 0 9.41147 0 0 12.5068 0 0 0 0 9.84815 0 0 0 0 0 0 9.95471 0 0 0 Q5VVJ2 MYSM1_HUMAN "Deubiquitinase MYSM1 (2A-DUB) (EC 3.4.19.-) (Myb-like, SWIRM and MPN domain-containing protein 1)" MYSM1 KIAA1915 Homo sapiens (Human) chromatin remodeling [GO:0006338]; immune system process [GO:0002376]; pigmentation [GO:0043473]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteolysis [GO:0006508]; regulation of cell migration [GO:0030334]; regulation of hair follicle development [GO:0051797]; regulation of hemopoiesis [GO:1903706] cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] DNA binding [GO:0003677]; histone binding [GO:0042393]; histone H2A deubiquitinase activity [GO:0140950]; metal ion binding [GO:0046872]; metal-dependent deubiquitinase activity [GO:0140492]; transcription coactivator activity [GO:0003713] 0.96963 -3.1244 GTKAWTPSCLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.476 0 0 0 0 0 0 0 0 Q5VVM6 CCD30_HUMAN Coiled-coil domain-containing protein 30 (Prefoldin subunit 6-like protein) CCDC30 PFDN6L Homo sapiens (Human) 0.96891 -8.3596 EGSFPREGQKEEGSQQNR 9.68013 0 0 0 0 0 0 9.20989 0 0 0 10.1272 0 0 9.36012 10.2952 0 0 0 0 10.7726 0 9.92665 0 0 0 0 Q5VVP1 S31A6_HUMAN Spermatogenesis-associated protein 31A6 (Protein FAM75A6) SPATA31A6 FAM75A6 Homo sapiens (Human) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] membrane [GO:0016020] 0.75066 0.31376 IQESLDLMQLR 14.1979 14.3311 0 0 11.9355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5VVS0 CA140_HUMAN Putative uncharacterized protein C1orf140 C1orf140 Homo sapiens (Human) 0.91437 -0.79606 TSEGLMRK 0 0 0 0 0 0 9.19461 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5VVW2 GARL3_HUMAN GTPase-activating Rap/Ran-GAP domain-like protein 3 GARNL3 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056] cytoplasm [GO:0005737] GTPase activator activity [GO:0005096] 0.96971 -4.7057 GPREIFHPEIQK 15.5106 15.5116 0 14.7399 0 14.8087 14.6853 15.6329 10.3832 14.0045 13.8222 14.7936 0 13.9796 15.5865 14.3447 14.2671 12.9932 0 0 11.2366 10.8022 0 0 0 0 0 Q5VVX9 UBE2U_HUMAN Ubiquitin-conjugating enzyme E2 U (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme U) (Ubiquitin carrier protein U) (Ubiquitin-protein ligase U) UBE2U Homo sapiens (Human) protein ubiquitination [GO:0016567] ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631] 0.88442 -0.29875 IATSKATEYYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.70719 0 0 0 Q5VVY1 NTM1B_HUMAN N-terminal Xaa-Pro-Lys N-methyltransferase 2 (EC 2.1.1.299) (Alpha N-terminal protein methyltransferase 1B) (Methyltransferase-like protein 11B) (X-Pro-Lys N-terminal protein methyltransferase 1B) (NTM1B) NTMT2 C1orf184 METTL11B NRMT2 Homo sapiens (Human) N-terminal protein amino acid methylation [GO:0006480] cytoplasm [GO:0005737]; nucleus [GO:0005634] N-terminal protein N-methyltransferase activity [GO:0071885] 0.96134 -2.5603 FVGGPGR 0 0 0 0 0 0 0 0 0 0 0 0 11.7685 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5VW00 DC122_HUMAN DDB1- and CUL4-associated factor 12-like protein 2 (WD repeat-containing protein 40C) DCAF12L2 WDR40C Homo sapiens (Human) Cul4-RING E3 ubiquitin ligase complex [GO:0080008] 0.95224 -1.4753 LVHYLKGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1572 10.3424 0 Q5VW32 BROX_HUMAN BRO1 domain-containing protein BROX (BRO1 domain- and CAAX motif-containing protein) BROX BROFTI C1orf58 Homo sapiens (Human) mitotic nuclear membrane reassembly [GO:0007084] extracellular exosome [GO:0070062]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965] 0.85457 0.10354 ENITEDEAK 0 0 0 0 0 0 0 12.0838 0 0 0 9.7219 9.36988 10.1312 10.1774 11.2083 0 10.865 0 0 0 0 0 0 0 0 0 Q5VW36 FOCAD_HUMAN Focadhesin FOCAD KIAA1797 Homo sapiens (Human) regulation of post-transcriptional gene silencing [GO:0060147] cytosol [GO:0005829]; focal adhesion [GO:0005925] 0.96952 -3.0428 AASIRDICK 0 0 9.18753 0 0 0 9.76172 0 0 9.95123 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5VWG9 TAF3_HUMAN Transcription initiation factor TFIID subunit 3 (140 kDa TATA box-binding protein-associated factor) (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (TAF(II)140) (TAF140) (TAFII-140) (TAFII140) TAF3 Homo sapiens (Human) maintenance of protein location in nucleus [GO:0051457]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; protein phosphorylation [GO:0006468]; RNA polymerase II preinitiation complex assembly [GO:0051123] male germ cell nucleus [GO:0001673]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor TFIID complex [GO:0005669] metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein heterodimerization activity [GO:0046982]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; transcription regulator inhibitor activity [GO:0140416] 0.96976 -6.0007 ETKYPWK 0 0 0 0 0 0 0 9.83468 0 10.0539 0 9.29547 0 0 0 0 0 0 0 8.1264 0 0 0 0 0 0 0 Q5VWJ9 SNX30_HUMAN Sorting nexin-30 SNX30 Homo sapiens (Human) autophagy of mitochondrion [GO:0000422]; endocytic recycling [GO:0032456]; piecemeal microautophagy of the nucleus [GO:0034727]; positive regulation of autophagosome assembly [GO:2000786]; protein transport [GO:0015031]; reticulophagy [GO:0061709] early endosome [GO:0005769]; early endosome membrane [GO:0031901]; phagophore assembly site [GO:0000407] phosphatidylinositol binding [GO:0035091] 0.96775 -2.9266 FSEEFVETR 0 0 8.99172 9.33521 0 0 9.01895 0 0 0 0 0 0 0 0 0 0 8.63963 0 0 0 0 0 0 0 0 0 Q5VWK0 NBPF6_HUMAN Neuroblastoma breakpoint family member 6 NBPF6 Homo sapiens (Human) cytoplasm [GO:0005737] 0.92605 -0.95956 APVPPRHHDK 0 0 8.50886 0 0 0 9.19832 9.77648 9.83477 0 0 0 0 0 0 0 0 0 0 0 0 9.50418 0 0 0 0 0 Q5VWK5 IL23R_HUMAN Interleukin-23 receptor (IL-23 receptor) (IL-23R) IL23R Homo sapiens (Human) cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-23-mediated signaling pathway [GO:0038155]; negative regulation of interleukin-10 production [GO:0032693]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of memory T cell differentiation [GO:0043382]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of NK T cell activation [GO:0051135]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 type immune response [GO:0002827]; positive regulation of T-helper 17 cell lineage commitment [GO:2000330]; positive regulation of T-helper 17 type immune response [GO:2000318]; positive regulation of type II interferon production [GO:0032729]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of tyrosine phosphorylation of STAT protein [GO:0042509]; response to lipopolysaccharide [GO:0032496]; response to type II interferon [GO:0034341] external side of plasma membrane [GO:0009897]; interleukin-23 receptor complex [GO:0072536]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896] 0.84918 0.11526 CQETGKRYWQPWSSLFFHK 0 0 0 0 0 0 0 0 0 9.72797 0 0 0 0 0 0 9.99661 0 0 0 0 0 0 0 0 0 0 Q5VWN6 TASO2_HUMAN Protein TASOR 2 TASOR2 C10orf18 FAM208B KIAA2006 Homo sapiens (Human) "negative regulation of gene expression, epigenetic [GO:0045814]" cytosol [GO:0005829]; nucleoplasm [GO:0005654] 0.96937 -5.5661 ELIKQVSPAASLR 0 0 0 0 0 0 0 0 9.32609 0 0 9.12443 0 0 0 0 0 0 8.8661 0 0 0 0 0 0 0 9.94427 Q5VWP2 TET5C_HUMAN Terminal nucleotidyltransferase 5C (EC 2.7.7.19) (Non-canonical poly(A) polymerase FAM46C) TENT5C FAM46C Homo sapiens (Human) in utero embryonic development [GO:0001701]; mRNA stabilization [GO:0048255]; negative regulation of cell differentiation [GO:0045596] centrosome [GO:0005813]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] poly(A) RNA polymerase activity [GO:1990817]; RNA binding [GO:0003723] 0.93972 -1.3248 LETYLQNHFAEEERSK 9.90061 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0554 0 0 0 0 0 0 0 0 0 0 0 0 Q5VWP3 MLIP_HUMAN Muscular LMNA-interacting protein (Cardiac Isl1-interacting protein) (CIP) (Muscular-enriched A-type laminin-interacting protein) MLIP C6orf142 Cip Homo sapiens (Human) negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of cardiac muscle hypertrophy in response to stress [GO:1903243]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944] cytosol [GO:0005829]; nuclear envelope [GO:0005635]; nuclear lumen [GO:0031981]; nucleus [GO:0005634]; PML body [GO:0016605]; sarcolemma [GO:0042383] 0.89758 -0.58318 ATFSSSEK 0 0 0 0 7.99904 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.62954 8.54689 9.2318 0 0 8.73352 Q5VWQ0 RSBN1_HUMAN Lysine-specific demethylase 9 (KDM9) (EC 1.14.11.-) (Round spermatid basic protein 1) RSBN1 Homo sapiens (Human) nucleus [GO:0005634] histone H4K20 demethylase activity [GO:0035575]; metal ion binding [GO:0046872] 0.89659 -0.53249 EVQTVCAGLTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.5499 0 0 0 0 0 10.645 0 0 0 0 0 0 Q5VWQ8 DAB2P_HUMAN Disabled homolog 2-interacting protein (DAB2 interaction protein) (DAB2-interacting protein) (ASK-interacting protein 1) (AIP-1) (DOC-2/DAB-2 interactive protein) DAB2IP AF9Q34 AIP1 KIAA1743 Homo sapiens (Human) angiogenesis [GO:0001525]; cell cycle [GO:0007049]; cell motility involved in cerebral cortex radial glia guided migration [GO:0021814]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to unfolded protein [GO:0034620]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; endothelial cell apoptotic process [GO:0072577]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; I-kappaB phosphorylation [GO:0007252]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; layer formation in cerebral cortex [GO:0021819]; negative regulation of angiogenesis [GO:0016525]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of GTPase activity [GO:0034260]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of phosphatidylinositol 3-kinase activity [GO:0043553]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; negative regulation of vascular endothelial growth factor signaling pathway [GO:1900747]; neuron projection morphogenesis [GO:0048812]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of dendrite development [GO:1900006]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron migration [GO:2001224]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of protein-containing complex assembly [GO:0031334]; positive regulation of synapse maturation [GO:0090129]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein catabolic process [GO:0030163]; regulation of cell cycle [GO:0051726]; regulation of GTPase activity [GO:0043087]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of p38MAPK cascade [GO:1900744]; regulation of protein-containing complex assembly [GO:0043254]; tube formation [GO:0035148]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324] AIP1-IRE1 complex [GO:1990597]; axon [GO:0030424]; cerebellar mossy fiber [GO:0044300]; climbing fiber [GO:0044301]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endocytic vesicle [GO:0030139]; neuronal cell body [GO:0043025]; neuronal cell body membrane [GO:0032809]; parallel fiber [GO:1990032]; plasma membrane [GO:0005886] 14-3-3 protein binding [GO:0071889]; cadherin binding [GO:0045296]; death receptor binding [GO:0005123]; GTPase activator activity [GO:0005096]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; mitogen-activated protein kinase kinase binding [GO:0031434]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein serine/threonine kinase activator activity [GO:0043539]; protein-containing complex binding [GO:0044877]; SH3 domain binding [GO:0017124]; signaling adaptor activity [GO:0035591]; vascular endothelial growth factor receptor 2 binding [GO:0043184] 0.96392 -2.2189 AVHPNKDNSRR 0 0 0 0 0 9.35652 0 0 0 0 0 0 0 9.59984 0 11.387 0 11.0208 0 0 0 0 0 8.86706 10.2359 0 10.3488 Q5VWT5 FYB2_HUMAN "FYN-binding protein 2 (Activation-dependent, raft-recruited ADAP-like phosphoprotein)" FYB2 ARAP C1orf168 Homo sapiens (Human) cell adhesion mediated by integrin [GO:0033627]; integrin-mediated signaling pathway [GO:0007229]; protein localization to plasma membrane [GO:0072659]; T cell receptor signaling pathway [GO:0050852] immunological synapse [GO:0001772]; membrane raft [GO:0045121]; plasma membrane [GO:0005886] 0.96995 -5.261 GAQTLPSQK 0 0 0 0 0 0 8.92077 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.68433 0 0 0 Q5VWZ2 LYPL1_HUMAN Lysophospholipase-like protein 1 (EC 3.1.2.22) LYPLAL1 Homo sapiens (Human) protein depalmitoylation [GO:0002084] cytoplasm [GO:0005737]; cytosol [GO:0005829] carboxylic ester hydrolase activity [GO:0052689]; lysophospholipase activity [GO:0004622]; palmitoyl-(protein) hydrolase activity [GO:0008474] 0.8808 0.009555 AAASGSVLQR 0 0 0 0 0 0 0 9.39253 0 0 0 0 0 0 0 0 10.5317 0 0 0 8.69307 0 0 0 0 0 0 Q5VX52 SPAT1_HUMAN Spermatogenesis-associated protein 1 (Sperm-specific protein SP-2) SPATA1 Homo sapiens (Human) acrosomal vesicle [GO:0001669] 0.96117 -2.0211 EKIIKQMK 0 0 0 0 0 0 0 11.3375 11.2912 0 0 0 0 0 0 0 10.5687 0 0 0 0 0 0 9.79988 0 0 0 Q5VXH4 PRAM6_HUMAN PRAME family member 6 PRAMEF6 Homo sapiens (Human) negative regulation of apoptotic process [GO:0043066]; negative regulation of cell differentiation [GO:0045596]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567] Cul2-RING ubiquitin ligase complex [GO:0031462]; cytoplasm [GO:0005737] ubiquitin ligase-substrate adaptor activity [GO:1990756] 0.96963 -3.1256 AELMKRVR 0 0 0 0 0 15.3589 0 0 11.0171 10.1687 0 0 0 0 14.5524 15.0963 15.0285 15.1341 0 10.0293 0 0 0 0 0 11.8066 0 Q5VXU3 CHIC1_HUMAN Cysteine-rich hydrophobic domain-containing protein 1 (Brain X-linked protein) CHIC1 BRX Homo sapiens (Human) cytoplasmic vesicle [GO:0031410]; plasma membrane [GO:0005886] 0.88078 -0.027874 ALPVNVK 0 0 0 0 0 0 0 0 0 0 12.0885 0 0 0 0 0 0 0 0 0 0 11.2316 0 0 0 0 0 Q5VXU9 SHOC1_HUMAN Protein shortage in chiasmata 1 ortholog (EC 3.6.-.-) (Protein ZIP2 homolog) (MZIP2) SHOC1 C9orf84 ZIP2 Homo sapiens (Human) reciprocal meiotic recombination [GO:0007131]; resolution of meiotic recombination intermediates [GO:0000712]; synaptonemal complex assembly [GO:0007130] chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794] ATP hydrolysis activity [GO:0016887]; single-stranded DNA binding [GO:0003697] 0.95923 -1.7086 ASFFVEDFLEK 0 0 0 0 0 0 0 0 0 0 0 0 8.88072 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5VYJ5 MALR1_HUMAN MAM and LDL-receptor class A domain-containing protein 1 MALRD1 C10orf112 DIET1 Homo sapiens (Human) cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858] cytoplasmic vesicle membrane [GO:0030659]; Golgi apparatus [GO:0005794] 0.96942 -3.5891 CDFKYDCPDK 0 12.8503 0 0 0 0 0 0 0 12.9423 0 11.3045 11.0163 9.46091 0 11.1665 11.5702 12.9587 0 0 0 0 0 0 0 0 0 Q5VYK3 ECM29_HUMAN Proteasome adapter and scaffold protein ECM29 (Ecm29 proteasome adapter and scaffold) (Proteasome-associated protein ECM29 homolog) ECPAS ECM29 KIAA0368 Homo sapiens (Human) proteasome assembly [GO:0043248]; ubiquitin-dependent ERAD pathway [GO:0030433] centrosome [GO:0005813]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; late endosome [GO:0005770]; membrane [GO:0016020]; multivesicular body [GO:0005771]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502] molecular adaptor activity [GO:0060090]; proteasome binding [GO:0070628] 0.96765 -3.712 AAMDSARLSAAK 0 0 0 0 10.0812 0 0 0 0 0 0 0 0 0 0 0 10.9733 0 0 0 0 0 0 0 0 0 0 Q5VYM1 CI131_HUMAN Uncharacterized protein C9orf131 C9orf131 Homo sapiens (Human) 0.91545 -0.76435 GVTCPGVKAEAPLSQR 0 0 0 0 0 0 0 0 8.26852 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5VYS4 MEDAG_HUMAN Mesenteric estrogen-dependent adipogenesis protein (Activated in W/Wv mouse stomach 3 homolog) (hAWMS3) (Mesenteric estrogen-dependent adipose 4) (MEDA-4) MEDAG AWMS3 C13orf33 MEDA4 Homo sapiens (Human) positive regulation of fat cell differentiation [GO:0045600] cytoplasm [GO:0005737] 0.87206 0.02719 VLNLSSTSPEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.81099 0 0 0 0 0 0 0 0 0 0 0 0 Q5VYS8 TUT7_HUMAN Terminal uridylyltransferase 7 (TUTase 7) (EC 2.7.7.52) (Zinc finger CCHC domain-containing protein 6) TUT7 HS2 KIAA1711 ZCCHC6 Homo sapiens (Human) miRNA metabolic process [GO:0010586]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; oocyte maturation [GO:0001556]; polyuridylation-dependent mRNA catabolic process [GO:1990074]; pre-miRNA processing [GO:0031054]; retrotransposon silencing by mRNA destabilization [GO:0141008]; RNA 3' uridylation [GO:0071076]; RNA 3'-end processing [GO:0031123] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654] miRNA binding [GO:0035198]; RNA binding [GO:0003723]; RNA uridylyltransferase activity [GO:0050265]; uridylyltransferase activity [GO:0070569]; zinc ion binding [GO:0008270] 0.96915 -7.4143 DCIDRLK 0 0 0 0 0 9.51909 0 9.1844 0 9.38614 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0051 0 0 0 Q5VZ46 K1614_HUMAN Uncharacterized protein KIAA1614 KIAA1614 Homo sapiens (Human) centrosome cycle [GO:0007098]; establishment or maintenance of cell polarity [GO:0007163]; regulation of cellular localization [GO:0060341] apical plasma membrane [GO:0016324]; cell cortex [GO:0005938]; nucleus [GO:0005634] 0.91477 -0.78195 FEDESAREAEFR 9.95565 9.78789 9.87498 0 10.213 0 9.79978 11.4991 0 0 11.3531 0 0 0 0 0 0 0 0 0 0 0 0 9.70501 0 0 0 Q5VZ52 MORN5_HUMAN MORN repeat-containing protein 5 MORN5 C9orf113 C9orf18 Homo sapiens (Human) 0.94332 -1.3345 YIGEYVDGRMEGK 0 8.90746 0 0 0 0 0 0 9.21298 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5VZ66 JKIP3_HUMAN Janus kinase and microtubule-interacting protein 3 (Neuroendocrine long coiled-coil protein 2) JAKMIP3 C10orf14 C10orf39 JAMIP3 NECC2 Homo sapiens (Human) Golgi apparatus [GO:0005794] kinase binding [GO:0019900]; microtubule binding [GO:0008017] 0.96927 -4.7646 AVFVLER 0 0 9.03103 0 0 10.7336 0 0 0 0 0 0 10.5714 0 0 0 0 0 0 0 8.9143 0 0 0 0 0 0 Q5VZ89 DEN4C_HUMAN DENN domain-containing protein 4C DENND4C C9orf55 C9orf55B Homo sapiens (Human) cellular response to insulin stimulus [GO:0032869]; protein localization to plasma membrane [GO:0072659]; protein transport [GO:0015031]; regulation of Rab protein signal transduction [GO:0032483] cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; insulin-responsive compartment [GO:0032593]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; retromer complex [GO:0030904] guanyl-nucleotide exchange factor activity [GO:0005085] 0.9595 -1.8273 IEDKGPR 0 0 13.7157 0 0 0 0 0 0 0 14.2301 14.1835 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5VZB9 DMRTA_HUMAN Doublesex- and mab-3-related transcription factor A1 DMRTA1 DMO Homo sapiens (Human) male mating behavior [GO:0060179]; ovarian follicle development [GO:0001541]; regulation of transcription by RNA polymerase II [GO:0006357]; sex differentiation [GO:0007548] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.065737 1.2967 ASGGGGR 13.4868 13.3604 13.5962 10.1825 9.9536 10.0083 13.5714 13.6805 13.6517 13.7524 13.81 13.4387 10.5095 10.1677 9.25611 11.225 10.2776 11.446 0 0 0 0 0 0 0 0 0 Q5VZE5 NAA35_HUMAN "N-alpha-acetyltransferase 35, NatC auxiliary subunit (Embryonic growth-associated protein homolog) (Protein MAK10 homolog)" NAA35 EGAP MAK10 Homo sapiens (Human) N-terminal peptidyl-methionine acetylation [GO:0017196]; N-terminal protein amino acid acetylation [GO:0006474]; negative regulation of apoptotic process [GO:0043066]; smooth muscle cell proliferation [GO:0048659] cytoplasm [GO:0005737]; cytosol [GO:0005829]; NatC complex [GO:0031417]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] 0.91425 -0.77874 DVEDDMQR 0 0 0 0 0 0 0 10.8965 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5VZI3 TM268_HUMAN Transmembrane protein 268 TMEM268 C9orf91 Homo sapiens (Human) membrane [GO:0016020] 0.95089 -1.3838 TSQESLLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.75736 0 0 0 0 0 0 0 0 0 Q5VZK9 CARL1_HUMAN "F-actin-uncapping protein LRRC16A (CARMIL homolog) (Capping protein regulator and myosin 1 linker protein 1) (Capping protein, Arp2/3 and myosin-I linker homolog 1) (Capping protein, Arp2/3 and myosin-I linker protein 1) (Leucine-rich repeat-containing protein 16A)" CARMIL1 CARMIL LRRC16 LRRC16A Homo sapiens (Human) actin filament network formation [GO:0051639]; actin filament organization [GO:0007015]; barbed-end actin filament uncapping [GO:0051638]; cell migration [GO:0016477]; lamellipodium assembly [GO:0030032]; macropinocytosis [GO:0044351]; negative regulation of barbed-end actin filament capping [GO:2000813]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell migration [GO:0030335]; positive regulation of lamellipodium organization [GO:1902745]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315]; ruffle organization [GO:0031529]; urate metabolic process [GO:0046415] cell leading edge [GO:0031252]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; filamentous actin [GO:0031941]; lamellipodium [GO:0030027]; macropinosome [GO:0044354]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] protein-containing complex binding [GO:0044877] 0.88563 -0.36683 IENYLLR 0 0 0 9.61842 9.5215 9.57824 10.3572 0 10.5417 0 0 0 8.73373 0 0 0 0 0 0 9.44429 0 0 0 0 10.0293 0 0 Q5VZL5 ZMYM4_HUMAN Zinc finger MYM-type protein 4 (Zinc finger protein 262) ZMYM4 KIAA0425 ZNF262 Homo sapiens (Human) cytoskeleton organization [GO:0007010]; regulation of cell morphogenesis [GO:0022604] DNA binding [GO:0003677]; zinc ion binding [GO:0008270] 0.96952 -3.4015 AEREVESGPR 0 10.604 0 0 0 0 0 0 0 11.9832 12.5587 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.44925 Q5VZP5 STYL2_HUMAN Serine/threonine/tyrosine-interacting-like protein 2 (Inactive dual specificity phosphatase 27) STYXL2 DUSP27 Homo sapiens (Human) negative regulation of MAPK cascade [GO:0043409]; protein dephosphorylation [GO:0006470] cytoplasm [GO:0005737]; sarcomere [GO:0030017] MAP kinase phosphatase activity [GO:0033549]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138] 0.96948 -4.6249 DKLTALERWK 0 0 0 0 0 0 0 0 0 9.18078 9.43041 9.83395 9.57962 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5VZR2 NTM2G_HUMAN NUT family member 2G NUTM2G FAM22G Homo sapiens (Human) 0.83624 0.19447 EVPDPQQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7.7896 0 0 0 Q5VZV1 MT21C_HUMAN Protein-lysine methyltransferase METTL21C (EC 2.1.1.-) (Methyltransferase-like protein 21C) METTL21C C13orf39 Homo sapiens (Human) cellular response to dexamethasone stimulus [GO:0071549]; hormone-mediated apoptotic signaling pathway [GO:0008628]; peptidyl-lysine methylation [GO:0018022]; protein methylation [GO:0006479]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; skeletal muscle tissue development [GO:0007519] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] heat shock protein binding [GO:0031072]; protein-lysine N-methyltransferase activity [GO:0016279] 0.76178 0.29816 ELVWGEDLDK 0 0 0 0 0 0 10.6468 10.5562 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5W041 ARMC3_HUMAN Armadillo repeat-containing protein 3 (Beta-catenin-like protein) (Cancer/testis antigen 81) (CT81) (KU-CT-1) ARMC3 Homo sapiens (Human) extracellular exosome [GO:0070062] 0.88339 -0.17912 LFHEQEVEK 0 0 0 0 0 0 0 0 0 0 0 0 9.62288 0 0 0 0 0 0 0 0 0 0 9.74012 0 0 0 Q5W0B7 TM236_HUMAN Transmembrane protein 236 TMEM236 FAM23A FAM23B Homo sapiens (Human) membrane [GO:0016020] 0.86382 0.076482 NILVTLSYIYFNYLTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2063 0 Q5W0N0 CI057_HUMAN Uncharacterized protein C9orf57 C9orf57 Homo sapiens (Human) membrane [GO:0016020] 0.63062 0.40055 ILQLHELVTTHCCNHSLCNF 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9317 0 0 0 0 0 0 0 0 0 0 0 0 0 Q5W0Q7 USPL1_HUMAN SUMO-specific isopeptidase USPL1 (EC 3.4.22.-) (Ubiquitin-specific peptidase-like protein 1) (USP-like 1) USPL1 C13orf22 D13S106 Homo sapiens (Human) Cajal body organization [GO:0030576]; cell population proliferation [GO:0008283]; protein desumoylation [GO:0016926]; snRNA transcription [GO:0009301] Cajal body [GO:0015030]; extracellular space [GO:0005615] deSUMOylase activity [GO:0016929]; SUMO binding [GO:0032183] 0.85462 0.10347 NTITDLQPSVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.94527 0 0 0 0 0 0 0 0 0 0 Q5W0V3 FHI2A_HUMAN FHF complex subunit HOOK interacting protein 2A (FHIP2A) FHIP2A FAM160B1 KIAA1600 Homo sapiens (Human) 0.95576 -1.5487 VLFDRMGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6915 0 0 0 0 0 0 Q5W0Z9 ZDH20_HUMAN Palmitoyltransferase ZDHHC20 (EC 2.3.1.225) (Acyltransferase ZDHHC20) (EC 2.3.1.-) (DHHC domain-containing cysteine-rich protein 20) (DHHC20) (Zinc finger DHHC domain-containing protein 20) ZDHHC20 Homo sapiens (Human) peptidyl-L-cysteine S-palmitoylation [GO:0018230]; positive regulation by host of viral process [GO:0044794]; protein palmitoylation [GO:0018345]; protein targeting to membrane [GO:0006612]; synaptic vesicle maturation [GO:0016188] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] palmitoyltransferase activity [GO:0016409]; protein-cysteine S-myristoyltransferase activity [GO:0019705]; protein-cysteine S-palmitoyltransferase activity [GO:0019706]; protein-cysteine S-stearoyltransferase activity [GO:0140439]; zinc ion binding [GO:0008270] 0.96934 -3.3723 AHHCSACDSCILK 0 0 0 0 0 0 0 0 8.12588 0 9.39466 0 0 0 0 0 0 9.61629 0 0 0 0 0 0 0 0 0 Q5W186 CST9_HUMAN Cystatin-9 (Cystatin-like molecule) CST9 CLM CTES7A Homo sapiens (Human) antimicrobial humoral response [GO:0019730]; negative regulation of peptidase activity [GO:0010466] extracellular space [GO:0005615] cysteine-type endopeptidase inhibitor activity [GO:0004869] 0.88195 -0.023522 LLRVLSSWREDSMDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.45477 0 0 0 0 0 0 0 Q5W188 CST9P_HUMAN Putative cystatin-9-like protein CST9LP1 (Cystatin-9-like pseudogene 1) CST9LP1 Homo sapiens (Human) antimicrobial humoral response [GO:0019730]; negative regulation of peptidase activity [GO:0010466] extracellular space [GO:0005615] cysteine-type endopeptidase inhibitor activity [GO:0004869] 0.96179 -2.0281 EQGYDKMTFSMNLQLGRTMCGK 0 0 0 0 8.85941 0 0 11.6742 0 0 0 0 0 0 0 10.2451 9.92495 0 0 0 0 9.29066 0 0 0 0 0 Q5XG92 EST4A_HUMAN Carboxylesterase 4A (EC 3.1.1.-) CES4A CES8 UNQ440/PRO873 Homo sapiens (Human) extracellular region [GO:0005576] carboxylic ester hydrolase activity [GO:0052689] 0.88516 -0.37597 FAPPEPPEPWKGIR 0 0 0 0 0 0 0 0 0 0 0 0 9.74014 0 9.91588 0 0 0 9.96636 0 0 0 0 0 0 0 0 Q5XKE5 K2C79_HUMAN "Keratin, type II cytoskeletal 79 (Cytokeratin-79) (CK-79) (Keratin-6-like) (Keratin-6L) (Keratin-79) (K79) (Type-II keratin Kb38)" KRT79 K6L KB38 KRT6L Homo sapiens (Human) keratinization [GO:0031424] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; keratin filament [GO:0045095] enzyme binding [GO:0019899]; structural constituent of skin epidermis [GO:0030280] 0.060606 1.3244 AEAEAWYQTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2141 10.3921 11.1037 11.8645 0 Q5XKL5 BTBD8_HUMAN BTB/POZ domain-containing protein 8 (AP2-interacting clathrin-endocytosis) (APache) BTBD8 KIAA1107 Homo sapiens (Human) axon [GO:0030424]; clathrin-coated vesicle [GO:0030136]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; presynapse [GO:0098793] 0.9693 -4.0984 EMGFTCKIQALRDK 0 8.85184 0 0 0 0 0 0 0 10.1223 0 10.4146 0 0 0 12.4217 0 0 0 0 0 0 0 0 0 9.94808 0 Q5XKP0 MIC13_HUMAN MICOS complex subunit MIC13 (Protein P117) MICOS13 C19orf70 MIC13 QIL1 Homo sapiens (Human) cristae formation [GO:0042407]; inner mitochondrial membrane organization [GO:0007007] MIB complex [GO:0140275]; MICOS complex [GO:0061617]; mitochondrial crista junction [GO:0044284]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; SAM complex [GO:0001401] 0.84846 0.157 SQAALQK 9.91577 9.98299 9.83406 0 0 0 10.1364 9.92102 9.90961 10.8897 11.0702 10.8722 0 0 0 0 0 0 0 0 13.1679 0 0 0 0 0 0 Q5XPI4 RN123_HUMAN E3 ubiquitin-protein ligase RNF123 (EC 2.3.2.27) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123) RNF123 KPC1 FP1477 Homo sapiens (Human) protein ubiquitination [GO:0016567]; proteolysis involved in protein catabolic process [GO:0051603] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear membrane [GO:0031965] metal ion binding [GO:0046872]; ubiquitin-protein transferase activity [GO:0004842] 0.92193 -1.1251 ESSKWRLR 0 0 0 0 0 0 0 13.3072 0 0 0 0 0 0 0 0 0 9.66635 0 0 0 0 0 0 0 0 0 Q5XUX0 FBX31_HUMAN F-box only protein 31 FBXO31 FBX14 FBX31 PP2386 Homo sapiens (Human) anaphase-promoting complex-dependent catabolic process [GO:0031145]; DNA damage response [GO:0006974]; mitotic G1 DNA damage checkpoint signaling [GO:0031571]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of neuron migration [GO:2001224]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] centrosome [GO:0005813]; cytosol [GO:0005829]; neuronal cell body [GO:0043025]; SCF ubiquitin ligase complex [GO:0019005] cyclin binding [GO:0030332] 0.92388 -1.1724 ESQPSPAQPR 0 11.6148 11.5142 0 0 12.3473 0 11.9502 0 0 0 0 0 9.90061 0 0 0 0 0 0 0 0 9.01789 0 0 0 0 Q5XX13 FBW10_HUMAN F-box/WD repeat-containing protein 10 (F-box and WD-40 domain-containing protein 10) (Ubiquitin ligase-specificity factor) FBXW10 Homo sapiens (Human) cytosol [GO:0005829] 0.96948 -3.3088 AQKQGQLETPGK 0 0 0 0 0 10.2232 0 0 0 10.5897 0 0 8.71421 0 9.19493 0 0 0 0 0 0 0 0 0 0 0 0 Q5XXA6 ANO1_HUMAN Anoctamin-1 (Discovered on gastrointestinal stromal tumors protein 1) (Oral cancer overexpressed protein 2) (Transmembrane protein 16A) (Tumor-amplified and overexpressed sequence 2) ANO1 DOG1 ORAOV2 TAOS2 TMEM16A Homo sapiens (Human) cellular response to heat [GO:0034605]; cellular response to peptide [GO:1901653]; chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; glial cell projection elongation [GO:0106091]; iodide transport [GO:0015705]; monoatomic cation transport [GO:0006812]; monoatomic ion transmembrane transport [GO:0034220]; mucus secretion [GO:0070254]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein localization to membrane [GO:0072657] apical plasma membrane [GO:0016324]; cell projection [GO:0042995]; chloride channel complex [GO:0034707]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; presynapse [GO:0098793] calcium activated cation channel activity [GO:0005227]; chloride channel activity [GO:0005254]; identical protein binding [GO:0042802]; intracellular calcium activated chloride channel activity [GO:0005229]; iodide transmembrane transporter activity [GO:0015111]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; voltage-gated chloride channel activity [GO:0005247] 0.88494 -0.24456 ITDPIQPK 9.1874 0 0 10.3144 0 0 0 0 0 10.1174 10.3491 10.4133 0 0 0 0 0 0 0 0 0 0 0 0 0 9.83223 0 Q60I27 AL2CL_HUMAN ALS2 C-terminal-like protein ALS2CL Homo sapiens (Human) endosomal transport [GO:0016197]; regulation of GTPase activity [GO:0043087] cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829] GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; small GTPase binding [GO:0031267] 0.97003 -4.3684 DLQEALLGFDVQSSR 0 0 10.5934 0 0 0 0 0 0 0 11.8399 0 0 0 0 10.8354 0 0 0 0 0 0 9.80184 0 0 0 0 Q629K1 TRIQK_HUMAN Triple QxxK/R motif-containing protein (Triple repetitive-sequence of QXXK/R protein homolog) TRIQK C8orf83 Homo sapiens (Human) endoplasmic reticulum membrane [GO:0005789] 0.91357 -0.75923 DAATIKLPVDQYR 0 0 9.87949 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q63HK3 ZKSC2_HUMAN Zinc finger protein with KRAB and SCAN domains 2 (Zinc finger protein 694) ZKSCAN2 ZNF694 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.60907 0.4313 IAGVHWSYEETK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.73278 0 0 0 0 0 Q63HK5 TSH3_HUMAN Teashirt homolog 3 (Zinc finger protein 537) TSHZ3 KIAA1474 TSH3 ZNF537 Homo sapiens (Human) "long-term synaptic potentiation [GO:0060291]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; regulation of respiratory gaseous exchange by nervous system process [GO:0002087]; regulation of transcription by RNA polymerase II [GO:0006357]" chromatin [GO:0000785]; growth cone [GO:0030426]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] "chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]" 0.060852 1.336 AAAYVSEELK 14.4549 14.3517 14.4539 11.7415 12.2388 12.0747 14.2819 13.981 14.2045 13.9562 14.1525 14.0763 11.7213 11.971 11.9372 12.6698 12.5673 12.4682 9.68278 0 0 0 0 0 9.70926 0 0 Q63HN8 RN213_HUMAN E3 ubiquitin-protein ligase RNF213 (EC 2.3.2.27) (EC 3.6.4.-) (ALK lymphoma oligomerization partner on chromosome 17) (E3 ubiquitin-lipopolysaccharide ligase RNF213) (EC 2.3.2.-) (Mysterin) (RING finger protein 213) RNF213 ALO17 C17orf27 KIAA1554 KIAA1618 MYSTR Homo sapiens (Human) angiogenesis [GO:0001525]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] cytoplasm [GO:0005737]; cytosol [GO:0005829]; lipid droplet [GO:0005811]; membrane [GO:0016020]; nucleolus [GO:0005730] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.96934 -5.6701 AYSPASR 0 0 0 15.8831 15.635 15.509 0 0 9.42057 8.93148 0 10.9553 9.61686 0 0 0 0 0 0 0 10.258 12.4202 0 10.3416 10.3617 11.8343 0 Q63HQ0 AP1AR_HUMAN AP-1 complex-associated regulatory protein (2c18) (Adaptor-related protein complex 1-associated regulatory protein) (Gamma-1-adaptin brefeldin A resistance protein) (GBAR) (Gamma-BAR) (Gamma-A1-adaptin and kinesin interactor) (Gadkin) AP1AR C4orf16 PRO0971 Homo sapiens (Human) "negative regulation of cell motility [GO:2000146]; negative regulation of receptor recycling [GO:0001920]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; protein transport [GO:0015031]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315]; substrate adhesion-dependent cell spreading [GO:0034446]; vesicle targeting, trans-Golgi to endosome [GO:0048203]" cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; transport vesicle [GO:0030133] AP-1 adaptor complex binding [GO:0035650]; kinesin binding [GO:0019894] 0.79042 0.24614 LEEEALYAAQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.686 0 Q63HQ2 EGFLA_HUMAN "Pikachurin (Agrin-like protein) (EGF-like, fibronectin type-III and laminin G-like domain-containing protein)" EGFLAM AGRINL AGRNL PIKA Homo sapiens (Human) extracellular matrix organization [GO:0030198]; peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan [GO:0019800]; positive regulation of cell-substrate adhesion [GO:0010811] basement membrane [GO:0005604]; cell projection [GO:0042995]; interstitial matrix [GO:0005614]; photoreceptor ribbon synapse [GO:0098684]; presynaptic active zone [GO:0048786]; synaptic cleft [GO:0043083] calcium ion binding [GO:0005509]; glycosaminoglycan binding [GO:0005539] 0.29867 0.8109 IVEGMAEGGFTQIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.728 0 0 Q63HR2 TENS2_HUMAN Tensin-2 (EC 3.1.3.48) (C1 domain-containing phosphatase and tensin homolog) (C1-TEN) (Tensin-like C1 domain-containing phosphatase) TNS2 KIAA1075 TENC1 Homo sapiens (Human) cellular homeostasis [GO:0019725]; collagen metabolic process [GO:0032963]; kidney development [GO:0001822]; multicellular organism growth [GO:0035264]; multicellular organismal-level homeostasis [GO:0048871]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of insulin receptor signaling pathway [GO:0046627]; peptidyl-tyrosine dephosphorylation [GO:0035335]; response to muscle activity [GO:0014850] cytoplasm [GO:0005737]; dendrite [GO:0030425]; focal adhesion [GO:0005925]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynapse [GO:0098794] identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; protein tyrosine phosphatase activity [GO:0004725] 0.51898 0.59807 LSYEIPTEEGGDR 0 0 0 0 0 0 0 0 0 0 9.07417 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q63ZE4 S22AA_HUMAN Solute carrier family 22 member 10 (Organic anion transporter 5) SLC22A10 OAT5 Homo sapiens (Human) organic anion transport [GO:0015711] membrane [GO:0016020] transmembrane transporter activity [GO:0022857] 0.40873 0.69085 CLALLTLNHMGRR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.65285 0 0 0 0 0 0 0 0 0 0 0 0 0 Q641Q2 WAC2A_HUMAN WASH complex subunit 2A WASHC2A FAM21A FAM21B Homo sapiens (Human) "endosomal transport [GO:0016197]; protein localization to endosome [GO:0036010]; protein transport [GO:0015031]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315]; retrograde transport, endosome to Golgi [GO:0042147]" cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; intracellular membrane-bounded organelle [GO:0043231]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; WASH complex [GO:0071203] phosphatidylinositol phosphate binding [GO:1901981]; retromer complex binding [GO:1905394] 0.96378 -2.23 AARRLAAQESSETEDMSVPR 0 13.3432 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q643R3 LPCT4_HUMAN Lysophospholipid acyltransferase LPCAT4 (1-acylglycerol-3-phosphate O-acyltransferase 7) (1-AGP acyltransferase 7) (1-AGPAT 7) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoserine O-acyltransferase) (EC 2.3.1.n6) (1-alkenylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.121) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acyltransferase-like 3) (Lysophosphatidylcholine acyltransferase 4) (Lysophosphatidylethanolamine acyltransferase 2) (EC 2.3.1.n7) (Plasmalogen synthase) LPCAT4 AGPAT7 AYTL3 LPEAT2 Homo sapiens (Human) phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid metabolic process [GO:0006644] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] 1-acylglycerol-3-phosphate O-acyltransferase activity [GO:0003841]; 1-acylglycerophosphocholine O-acyltransferase activity [GO:0047184]; 1-acylglycerophosphoethanolamine O-acyltransferase activity [GO:0106262]; 1-acylglycerophosphoserine O-acyltransferase activity [GO:0106263]; 1-alkenylglycerophosphoethanolamine O-acyltransferase activity [GO:0047166]; 1-alkylglycerophosphocholine O-acetyltransferase activity [GO:0047192]; 2-acylglycerol-3-phosphate O-acyltransferase activity [GO:0047144]; lysophosphatidic acid acyltransferase activity [GO:0042171]; lysophospholipid acyltransferase activity [GO:0071617] 0.87005 0.046429 VALEPQLWELGK 0 0 0 0 0 0 0 0 0 0 0 0 0 8.55301 0 0 0 0 0 0 0 0 0 0 0 0 0 Q64ET8 FRG2_HUMAN Protein FRG2 (FSHD region gene 2 protein) FRG2 FRG2A Homo sapiens (Human) nucleus [GO:0005634] 0.89693 -0.58436 ACTGHSKRHR 0 9.64153 9.69862 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q64LD2 WDR25_HUMAN WD repeat-containing protein 25 WDR25 C14orf67 Homo sapiens (Human) 0.9617 -2.0429 DSADRTIIAWDFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.7273 0 0 0 0 0 0 0 0 0 0 Q658L1 SAXO2_HUMAN Stabilizer of axonemal microtubules 2 SAXO2 FAM154B Homo sapiens (Human) axonemal microtubule [GO:0005879]; centriole [GO:0005814]; ciliary basal body [GO:0036064]; cytoskeleton [GO:0005856]; sperm flagellum [GO:0036126] microtubule binding [GO:0008017] 0.88634 -0.36499 LDTVPTYKDDYRAWDLHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.26611 0 0 0 0 9.42815 10.4795 0 0 Q658N2 WSCD1_HUMAN Sialate:O-sulfotransferase 1 (WSC domain-containing protein 1) WSCD1 KIAA0523 Homo sapiens (Human) Golgi membrane [GO:0000139] sulfotransferase activity [GO:0008146] 0.92118 -0.93456 GEKDHWR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.91588 0 10.5704 0 0 0 0 0 9.68271 10.5962 0 9.52689 0 Q658Y4 F91A1_HUMAN Protein FAM91A1 FAM91A1 Homo sapiens (Human) intracellular protein transport [GO:0006886]; vesicle tethering to Golgi [GO:0099041] cytoplasmic vesicle [GO:0031410]; trans-Golgi network [GO:0005802] 0.84809 0.12398 ICTLPEK 0 0 0 0 0 0 0 0 0 0 9.51068 0 0 0 0 0 10.5951 0 0 0 0 0 0 9.68626 0 0 0 Q659A1 ICE2_HUMAN Little elongation complex subunit 2 (Interactor of little elongator complex ELL subunit 2) (NMDA receptor-regulated protein 2) ICE2 BRCC1 NARG2 UNQ3101/PRO10100 Homo sapiens (Human) positive regulation of transcription by RNA polymerase III [GO:0045945]; snRNA transcription by RNA polymerase II [GO:0042795]; snRNA transcription by RNA polymerase III [GO:0042796] Cajal body [GO:0015030]; cytosol [GO:0005829]; euchromatin [GO:0000791]; histone locus body [GO:0035363]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; transcription elongation factor complex [GO:0008023] 0.95945 -1.7161 VPYPRFSR 0 9.2833 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q659C4 LAR1B_HUMAN La-related protein 1B (La ribonucleoprotein domain family member 1B) (La ribonucleoprotein domain family member 2) (La-related protein 2) LARP1B LARP2 Homo sapiens (Human) positive regulation of translation [GO:0045727] cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleus [GO:0005634] RNA binding [GO:0003723] 0.9701 -4.3456 HSSTSGEESNR 9.45278 0 9.55585 0 0 0 9.75832 0 0 12.7135 9.63949 9.87288 10.1032 10.0898 10.158 10.4086 10.1591 10.8348 0 0 0 0 0 0 0 0 0 Q66GS9 CP135_HUMAN Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4) CEP135 CEP4 KIAA0635 Homo sapiens (Human) centriole replication [GO:0007099]; centriole-centriole cohesion [GO:0010457]; positive regulation of establishment of protein localization [GO:1904951]; positive regulation of non-motile cilium assembly [GO:1902857] centriole [GO:0005814]; centrosome [GO:0005813]; cytosol [GO:0005829] 0.9693 -5.5721 DKEFHSHLTSHEK 0 0 0 0 0 0 0 0 0 10.3216 8.88634 0 10.413 0 9.65066 0 0 10.5232 0 12.0976 0 0 0 0 0 0 0 Q66K14 TBC9B_HUMAN TBC1 domain family member 9B TBC1D9B KIAA0676 Homo sapiens (Human) activation of GTPase activity [GO:0090630] membrane [GO:0016020] calcium ion binding [GO:0005509]; GTPase activator activity [GO:0005096] 0.9695 -3.4602 ANPFFVLQR 0 0 0 10.6245 0 0 0 0 0 0 0 0 10.1046 0 0 0 0 10.0764 0 0 0 0 0 0 0 0 9.67145 Q66K41 Z385C_HUMAN Zinc finger protein 385C ZNF385C Homo sapiens (Human) nucleus [GO:0005634] nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270] 0.079457 1.2389 KLFISCNICHLR 0 0 0 0 0 11.5868 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q66K89 E4F1_HUMAN Transcription factor E4F1 (EC 2.3.2.27) (E4F transcription factor 1) (Putative E3 ubiquitin-protein ligase E4F1) (RING-type E3 ubiquitin transferase E4F1) (Transcription factor E4F) (p120E4F) (p50E4F) E4F1 E4F Homo sapiens (Human) "cell cycle [GO:0007049]; cell division [GO:0051301]; DNA replication [GO:0006260]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; regulation of cell cycle process [GO:0010564]; regulation of mitotic cell cycle, embryonic [GO:0009794]; regulation of transcription by RNA polymerase II [GO:0006357]" cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; spindle [GO:0005819] "cAMP response element binding [GO:0035497]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transferase activity [GO:0016740]" 0.92383 -1.0213 DVVVSKEDAR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1334 0 0 0 0 0 0 0 0 0 0 0 0 10.7198 Q66LE6 2ABD_HUMAN Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (PP2A subunit B isoform B55-delta) (PP2A subunit B isoform PR55-delta) (PP2A subunit B isoform R2-delta) (PP2A subunit B isoform delta) PPP2R2D KIAA1541 Homo sapiens (Human) cell division [GO:0051301]; exit from mitosis [GO:0010458]; mitotic cell cycle [GO:0000278] cytosol [GO:0005829]; protein phosphatase type 2A complex [GO:0000159] protein phosphatase regulator activity [GO:0019888] 0.90526 -0.73106 ISERDKR 0 0 0 0 0 0 0 0 0 0 0 10.1936 0 0 0 0 0 0 9.80932 0 0 0 0 0 0 0 0 Q674X7 KAZRN_HUMAN Kazrin KAZN C1orf196 KAZ KIAA1026 HRIHFB2003 Homo sapiens (Human) keratinization [GO:0031424] cornified envelope [GO:0001533]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; desmosome [GO:0030057]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654] 0.93841 -1.2943 EALQERR 0 0 0 0 0 0 0 8.79607 8.86654 0 0 0 0 0 0 0 10.3484 0 10.6524 0 9.74197 0 0 0 0 0 0 Q684P5 RPGP2_HUMAN Rap1 GTPase-activating protein 2 (Rap1GAP2) (GTPase-activating Rap/Ran-GAP domain-like protein 4) RAP1GAP2 GARNL4 KIAA1039 RAP1GA2 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; adaptive immune response [GO:0002250]; regulation of cell size [GO:0008361]; regulation of small GTPase mediated signal transduction [GO:0051056] centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] GTPase activator activity [GO:0005096] 0.90296 -0.699 LKENGRAISR 0 12.558 0 0 0 0 0 0 8.74329 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.42725 0 0 0 Q687X5 STEA4_HUMAN "Metalloreductase STEAP4 (EC 1.16.1.9) (Six-transmembrane epithelial antigen of prostate 4) (SixTransMembrane protein of prostate 2) (Tumor necrosis factor, alpha-induced protein 9)" STEAP4 STAMP2 TNFAIP9 Homo sapiens (Human) copper ion import [GO:0015677]; fat cell differentiation [GO:0045444]; iron import into cell [GO:0033212]; iron ion transmembrane transport [GO:0034755]; protein homotrimerization [GO:0070207] early endosome membrane [GO:0031901]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] cupric reductase activity [GO:0008823]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; ferric-chelate reductase (NADPH) activity [GO:0052851]; heme binding [GO:0020037]; metal ion binding [GO:0046872] 0.40991 0.69411 FLSPSNLR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.63396 9.78599 9.41308 9.80589 9.87828 0 0 0 0 0 0 0 0 0 Q68BL7 OLM2A_HUMAN Olfactomedin-like protein 2A (Photomedin-1) OLFML2A UNQ9394/PRO34319 Homo sapiens (Human) extracellular matrix organization [GO:0030198]; signal transduction [GO:0007165] extracellular matrix [GO:0031012]; extracellular space [GO:0005615] extracellular matrix binding [GO:0050840]; identical protein binding [GO:0042802] 0.92992 -1.2438 HHSYGRHEGAWMK 9.01511 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q68BL8 OLM2B_HUMAN Olfactomedin-like protein 2B (Photomedin-2) OLFML2B Homo sapiens (Human) extracellular matrix organization [GO:0030198]; signal transduction [GO:0007165] extracellular matrix [GO:0031012]; extracellular space [GO:0005615] extracellular matrix binding [GO:0050840]; identical protein binding [GO:0042802] 0.95403 -1.5234 NLTKENEQIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.92665 0 0 0 0 Q68CJ6 SLIP_HUMAN Nuclear GTPase SLIP-GC (EC 3.6.1.-) (Speckled-like pattern in the germinal center) NUGGC C8orf80 HMFN0672 Homo sapiens (Human) cellular response to lipopolysaccharide [GO:0071222]; negative regulation of apoptotic process [GO:0043066]; regulation of nuclear cell cycle DNA replication [GO:0033262] nuclear speck [GO:0016607] GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.88952 -0.44122 AGPPGTSL 0 0 0 0 0 0 0 0 0 0 0 8.89794 0 0 0 0 0 9.56285 0 0 0 0 8.30606 9.34339 0 0 0 Q68CK6 ACS2B_HUMAN "Acyl-coenzyme A synthetase ACSM2B, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 2B) (Benzoate--CoA ligase) (EC 6.2.1.25) (Butyrate--CoA ligase 2B) (Butyryl-coenzyme A synthetase 2B) (Middle-chain acyl-CoA synthetase 2B) (Xenobiotic/medium-chain fatty acid-CoA ligase HXM-A)" ACSM2B ACSM2 HYST1046 Homo sapiens (Human) acyl-CoA metabolic process [GO:0006637]; fatty acid biosynthetic process [GO:0006633]; xenobiotic metabolic process [GO:0006805] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; benzoate-CoA ligase activity [GO:0018858]; butyrate-CoA ligase activity [GO:0047760]; CoA-ligase activity [GO:0016405]; decanoate-CoA ligase activity [GO:0102391]; fatty acid ligase activity [GO:0015645]; fatty-acyl-CoA synthase activity [GO:0004321]; metal ion binding [GO:0046872] 0.95483 -1.5734 LQMSKAK 11.3974 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q68CP4 HGNAT_HUMAN Heparan-alpha-glucosaminide N-acetyltransferase (EC 2.3.1.78) (Transmembrane protein 76) HGSNAT TMEM76 Homo sapiens (Human) heparan sulfate proteoglycan catabolic process [GO:0030200]; lysosomal transport [GO:0007041]; protein complex oligomerization [GO:0051259] lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821] acyltransferase activity [GO:0016746]; heparan-alpha-glucosaminide N-acetyltransferase activity [GO:0015019] 0.95463 -1.574 DAQAAPPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4613 0 0 0 0 0 0 0 0 Q68CP9 ARID2_HUMAN AT-rich interactive domain-containing protein 2 (ARID domain-containing protein 2) (BRG1-associated factor 200) (BAF200) (Zinc finger protein with activation potential) (Zipzap/p200) ARID2 BAF200 KIAA1557 Homo sapiens (Human) cardiac muscle cell proliferation [GO:0060038]; chromatin remodeling [GO:0006338]; coronary artery morphogenesis [GO:0060982]; embryonic organ development [GO:0048568]; heart morphogenesis [GO:0003007]; homeostatic process [GO:0042592]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; nucleosome disassembly [GO:0006337]; positive regulation of cell differentiation [GO:0045597]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of T cell differentiation [GO:0045582]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; kinetochore [GO:0000776]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; RSC-type complex [GO:0016586]; SWI/SNF complex [GO:0016514] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.96181 -2.5869 CLYELNFTVQSKEQEK 10.2075 9.36715 10.0703 0 0 0 9.47748 0 0 0 11.0557 9.56444 0 9.09814 0 0 0 0 0 0 0 10.9347 10.0967 0 0 0 0 Q68CQ1 MROH7_HUMAN Maestro heat-like repeat-containing protein family member 7 (HEAT repeat-containing protein 8) MROH7 C1orf175 HEATR8 Homo sapiens (Human) cytoplasm [GO:0005737]; extracellular space [GO:0005615]; membrane [GO:0016020] 0.4867 0.62085 DLLDLLLGSLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1267 0 0 0 0 0 0 0 0 0 0 0 Q68CQ4 UTP25_HUMAN U3 small nucleolar RNA-associated protein 25 homolog (Digestive organ expansion factor homolog) (UTP25 small subunit processor component) UTP25 C1orf107 DEF DIEXF Homo sapiens (Human) "embryonic organ development [GO:0048568]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; positive regulation of embryonic development [GO:0040019]; protein catabolic process [GO:0030163]; protein destabilization [GO:0031648]; protein localization to nucleolus [GO:1902570]" nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040] RNA binding [GO:0003723]; rRNA binding [GO:0019843]; U3 snoRNA binding [GO:0034511] 0.91445 -0.81996 ASQDPFLQHVNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1352 0 0 0 0 0 0 0 0 0 0 9.5636 Q68CZ1 FTM_HUMAN Protein fantom (Nephrocystin-8) (RPGR-interacting protein 1-like protein) (RPGRIP1-like protein) RPGRIP1L FTM KIAA1005 NPHP8 Homo sapiens (Human) cerebellum development [GO:0021549]; cochlea development [GO:0090102]; corpus callosum development [GO:0022038]; determination of left/right symmetry [GO:0007368]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; establishment of planar polarity [GO:0001736]; establishment or maintenance of cell polarity [GO:0007163]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lateral ventricle development [GO:0021670]; liver development [GO:0001889]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; neural tube patterning [GO:0021532]; non-motile cilium assembly [GO:1905515]; nose development [GO:0043584]; olfactory bulb development [GO:0021772]; pericardium development [GO:0060039]; regulation of smoothened signaling pathway [GO:0008589]; retinal rod cell development [GO:0046548] axonemal microtubule [GO:0005879]; axoneme [GO:0005930]; bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary rootlet [GO:0035253]; ciliary transition zone [GO:0035869]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; photoreceptor connecting cilium [GO:0032391]; plasma membrane [GO:0005886] thromboxane A2 receptor binding [GO:0031870] 0.91541 -0.77676 EQQATDQRSNIR 0 8.75245 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.7224 0 0 0 0 0 0 Q68CZ2 TENS3_HUMAN Tensin-3 (EC 3.1.3.-) (Tensin-like SH2 domain-containing protein 1) (Tumor endothelial marker 6) TNS3 TEM6 TENS1 TPP Homo sapiens (Human) dephosphorylation [GO:0016311] cell projection [GO:0042995]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; podosome [GO:0002102] phosphoprotein phosphatase activity [GO:0004721] 0.96367 -2.439 ERTFGSREPK 0 0 0 0 0 0 0 0 0 0 9.66569 0 0 0 9.05246 0 0 0 0 0 0 0 0 0 0 0 0 Q68D06 SLN13_HUMAN Schlafen family member 13 (EC 3.1.-.-) (Schlafen-13) (hSLFN13) SLFN13 Homo sapiens (Human) defense response to virus [GO:0051607]; rRNA catabolic process [GO:0016075]; tRNA catabolic process [GO:0016078] cytoplasm [GO:0005737] ATP binding [GO:0005524]; RNA endonuclease activity [GO:0004521]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270] 0.96058 -1.804 AETRETFLR 8.69773 0 0 0 0 0 0 0 0 9.98726 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q68D10 SPT2_HUMAN Protein SPT2 homolog (Protein KU002155) (SPT2 domain-containing protein 1) SPTY2D1 Homo sapiens (Human) heterochromatin formation [GO:0031507]; nucleosome assembly [GO:0006334]; regulation of DNA-templated transcription [GO:0006355]; transcription by RNA polymerase I [GO:0006360] nucleolus [GO:0005730]; nucleoplasm [GO:0005654] DNA binding [GO:0003677]; histone binding [GO:0042393]; histone chaperone activity [GO:0140713]; RNA polymerase I core binding [GO:0001042] 0.89844 -0.57739 EIFGYDRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.34687 9.53986 0 0 Q68D42 TM215_HUMAN Transmembrane protein 215 TMEM215 Homo sapiens (Human) negative regulation of retinal cell programmed cell death [GO:0046671]; sprouting angiogenesis [GO:0002040] membrane [GO:0016020] 0.76956 0.26849 MRPDDINPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2656 Q68D51 DEN2C_HUMAN DENN domain-containing protein 2C DENND2C Homo sapiens (Human) nucleoplasm [GO:0005654] guanyl-nucleotide exchange factor activity [GO:0005085] 0.95269 -1.4631 LHSYTGK 0 0 0 0 9.35903 0 8.97189 10.4021 10.5014 0 0 10.7548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q68D85 NR3L1_HUMAN Natural cytotoxicity triggering receptor 3 ligand 1 (B7 homolog 6) (B7-H6) NCR3LG1 B7H6 Homo sapiens (Human) plasma membrane [GO:0005886] 0.92388 -1.0497 SGDASLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.88264 0 0 11.0033 Q68D91 MBLC2_HUMAN Acyl-coenzyme A thioesterase MBLAC2 (Acyl-CoA thioesterase MBLAC2) (EC 3.1.2.2) (Beta-lactamase MBLAC2) (EC 3.5.2.6) (Metallo-beta-lactamase domain-containing protein 2) (Palmitoyl-coenzyme A thioesterase MBLAC2) MBLAC2 Homo sapiens (Human) fatty acid metabolic process [GO:0006631] endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] beta-lactamase activity [GO:0008800]; metal ion binding [GO:0046872]; myristoyl-CoA hydrolase activity [GO:0102991]; palmitoyl-CoA hydrolase activity [GO:0016290] 0.87133 0.064881 VLPGHFNTFGAER 0 0 0 0 0 0 0 0 0 0 0 0 0 9.6374 0 0 0 0 0 0 0 0 0 0 0 0 0 Q68DA7 FMN1_HUMAN Formin-1 (Limb deformity protein homolog) FMN1 FMN LD Homo sapiens (Human) actin nucleation [GO:0045010]; forelimb morphogenesis [GO:0035136]; gene expression [GO:0010467]; hindlimb morphogenesis [GO:0035137]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of actin nucleation [GO:0051127]; positive regulation of focal adhesion assembly [GO:0051894]; skeletal system morphogenesis [GO:0048705]; ureteric bud invasion [GO:0072092] actin filament [GO:0005884]; adherens junction [GO:0005912]; cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; nucleus [GO:0005634]; plasma membrane [GO:0005886] actin binding [GO:0003779]; microtubule binding [GO:0008017]; SH3 domain binding [GO:0017124] 0.96876 -3.333 LPSPQQHHR 9.91286 10.0238 9.94637 0 0 0 0 0 0 11.7607 11.6815 11.3629 0 8.84254 0 0 0 0 9.539 0 11.0144 0 0 0 0 10.5256 0 Q68DC2 ANKS6_HUMAN Ankyrin repeat and SAM domain-containing protein 6 (Ankyrin repeat domain-containing protein 14) (SamCystin) (Sterile alpha motif domain-containing protein 6) (SAM domain-containing protein 6) ANKS6 ANKRD14 PKDR1 SAMD6 Homo sapiens (Human) determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822] ciliary inversin compartment [GO:0097543]; cytoplasm [GO:0005737] 0.96337 -2.1364 HNGKADPMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.41022 0 0 0 0 0 0 0 Q68DD2 PA24F_HUMAN Cytosolic phospholipase A2 zeta (cPLA2-zeta) (EC 3.1.1.4) (Phospholipase A2 group IVF) PLA2G4F Homo sapiens (Human) arachidonic acid secretion [GO:0050482]; cellular response to antibiotic [GO:0071236]; cellular response to organic cyclic compound [GO:0071407]; glycerophospholipid catabolic process [GO:0046475]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; prostaglandin biosynthetic process [GO:0001516] cytosol [GO:0005829]; mitochondrion [GO:0005739]; ruffle membrane [GO:0032587]; vesicle [GO:0031982] calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; calcium-dependent phospholipid binding [GO:0005544]; lysophospholipase activity [GO:0004622]; phospholipase A1 activity [GO:0008970] 0.95244 -1.4747 LLQLQPEPR 0 0 0 0 8.84515 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q68DE3 USF3_HUMAN Basic helix-loop-helix domain-containing protein USF3 (Upstream transcription factor 3) USF3 KIAA2018 Homo sapiens (Human) negative regulation of epithelial to mesenchymal transition [GO:0010719]; positive regulation of transcription by RNA polymerase II [GO:0045944] nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; protein dimerization activity [GO:0046983]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.88515 -0.37094 NKSLAIHNMQGR 0 0 0 0 0 0 0 0 0 0 0 0 9.67647 0 0 0 0 0 0 0 0 9.25826 0 9.18827 0 0 0 Q68DI1 ZN776_HUMAN Zinc finger protein 776 ZNF776 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96963 -4.1682 GNLIKHQR 0 0 0 0 0 0 0 0 0 0 0 10.2194 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q68DK2 ZFY26_HUMAN Zinc finger FYVE domain-containing protein 26 (FYVE domain-containing centrosomal protein) (FYVE-CENT) (Spastizin) ZFYVE26 KIAA0321 Homo sapiens (Human) autophagosome organization [GO:1905037]; double-strand break repair via homologous recombination [GO:0000724]; lysosome organization [GO:0007040]; mitotic cytokinesis [GO:0000281]; regulation of cytokinesis [GO:0032465] centrosome [GO:0005813]; early endosome [GO:0005769]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; midbody [GO:0030496] metal ion binding [GO:0046872]; phosphatidylinositol-3-phosphate binding [GO:0032266]; protein kinase binding [GO:0019901] 0.95161 -1.3977 AYLICCK 11.372 11.1346 11.112 0 0 0 11.1706 0 11.2241 9.55215 0 11.3555 0 10.2312 10.9459 0 0 10.5069 0 0 0 0 0 0 0 9.38933 0 Q68DK7 MSL1_HUMAN Male-specific lethal 1 homolog (MSL-1) (Male-specific lethal 1-like 1) (MSL1-like 1) (Male-specific lethal-1 homolog 1) MSL1 MSL1L1 Homo sapiens (Human) chromatin remodeling [GO:0006338]; histone H4-K16 acetylation [GO:0043984]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of dosage compensation by inactivation of X chromosome [GO:1900095] MSL complex [GO:0072487]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682] 0.9643 -2.2794 EETELSEKIK 0 0 0 0 8.53356 0 0 0 0 0 0 0 9.8435 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q68DL7 CR063_HUMAN Uncharacterized protein C18orf63 C18orf63 Homo sapiens (Human) 0.75855 0.29917 EVGTSDHR 11.7272 11.5246 0 11.2183 0 0 11.7397 11.8336 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2077 0 0 0 10.3055 0 Q68DN1 CB016_HUMAN Uncharacterized protein C2orf16 C2orf16 Homo sapiens (Human) extracellular exosome [GO:0070062]; nucleus [GO:0005634] 0.9695 -3.4633 GPSERTRHNPSWR 0 0 0 0 8.852 0 0 0 0 0 11.6573 11.2716 0 0 0 0 0 0 0 0 10.936 0 10.3741 0 0 0 0 Q68DQ2 CRBG3_HUMAN Very large A-kinase anchor protein (vlAKAP) (Beta/gamma crystallin domain-containing protein 3) CRYBG3 Homo sapiens (Human) lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601] protein-containing complex [GO:0032991] carbohydrate binding [GO:0030246]; protein kinase A binding [GO:0051018]; structural constituent of eye lens [GO:0005212] 0.96966 -5.9144 EGLIAHENRLPTYFR 0 10.1085 0 0 0 0 0 10.0322 10.5286 13.5394 12.8669 15.1381 0 0 0 0 0 0 10.1824 0 0 10.6284 0 0 8.93472 0 0 Q68DU8 KCD16_HUMAN BTB/POZ domain-containing protein KCTD16 (Potassium channel tetramerization domain-containing protein 16) KCTD16 KIAA1317 Homo sapiens (Human) protein homooligomerization [GO:0051260]; regulation of G protein-coupled receptor signaling pathway [GO:0008277] cell projection [GO:0042995]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235] 0.91561 -0.76865 DGFLFRYILDYLR 0 0 0 0 0 9.05867 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q68DY1 ZN626_HUMAN Zinc finger protein 626 ZNF626 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.9268 -1.2064 AFKCSSNLTTHK 0 0 0 0 0 0 0 0 0 9.34283 0 0 0 0 0 9.20198 0 0 0 0 0 0 0 0 0 0 0 Q68DY9 ZN772_HUMAN Zinc finger protein 772 ZNF772 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.53122 0.58261 KDSLVQHQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.90718 0 Q68E01 INT3_HUMAN Integrator complex subunit 3 (Int3) (SOSS complex subunit A) (Sensor of single-strand DNA complex subunit A) (SOSS-A) (Sensor of ssDNA subunit A) INTS3 C1orf193 C1orf60 Homo sapiens (Human) DNA damage response [GO:0006974]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; mitotic G2/M transition checkpoint [GO:0044818]; regulation of transcription elongation by RNA polymerase II [GO:0034243]; response to ionizing radiation [GO:0010212]; snRNA processing [GO:0016180] cytoplasm [GO:0005737]; integrator complex [GO:0032039]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]; SOSS complex [GO:0070876] 0.92016 -0.92922 KAALSSPRSR 0 0 18.1394 0 0 0 0 0 12.4116 0 0 0 0 0 0 11.6835 0 12.1868 0 0 0 0 0 0 0 0 0 Q68EA5 ZNF57_HUMAN Zinc finger protein 57 (Zinc finger protein 424) ZNF57 ZNF424 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.70137 0.37213 IHTQEQLYK 0 0 0 10.9699 11.2212 11.0464 0 0 0 0 0 12.8871 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q68G74 LHX8_HUMAN LIM/homeobox protein Lhx8 (LIM homeobox protein 8) LHX8 Homo sapiens (Human) female gonad development [GO:0008585]; forebrain neuron development [GO:0021884]; learning or memory [GO:0007611]; neuron differentiation [GO:0030182]; odontogenesis of dentin-containing tooth [GO:0042475]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; female germ cell nucleus [GO:0001674]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96788 -3.6688 DIFCKLDYFR 0 0 0 0 0 0 0 0 0 0 10.9395 0 9.93114 0 0 0 0 0 0 0 9.33546 0 0 0 0 0 10.3365 Q68G75 LEMD1_HUMAN LEM domain-containing protein 1 (Cancer/testis antigen 50) (CT50) (LEM domain protein 1) (LEMP-1) LEMD1 Homo sapiens (Human) membrane [GO:0016020] 0.96367 -2.2267 APSTRITYGTITK 0 10.8897 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q69YH5 CDCA2_HUMAN Cell division cycle-associated protein 2 (Recruits PP1 onto mitotic chromatin at anaphase protein) (Repo-Man) CDCA2 Homo sapiens (Human) cell division [GO:0051301]; chromosome segregation [GO:0007059]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of chromosome segregation [GO:0051983]; regulation of mitotic nuclear division [GO:0007088] chromosome [GO:0005694]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.96144 -2.6038 AKNKSESENEPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1506 0 0 10.4229 0 0 0 0 0 Q69YL0 NCAS2_HUMAN Protein NCBP2AS2 (Hypoxia-induced angiogenesis regulator) (NCBP2 antisense gene protein 2) NCBP2AS2 HIAR Homo sapiens (Human) 0.95472 -1.5015 GRSGPPPGSQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1613 0 0 0 0 0 0 0 Q69YN2 C19L1_HUMAN CWF19-like protein 1 (C19L1) CWF19L1 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]" post-mRNA release spliceosomal complex [GO:0071014] RNA lariat debranching enzyme activator activity [GO:0061632] 0.80936 0.23267 GVDILLTSPWPK 8.69808 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q69YN4 VIR_HUMAN Protein virilizer homolog VIRMA KIAA1429 MSTP054 Homo sapiens (Human) mRNA alternative polyadenylation [GO:0110104]; mRNA methylation [GO:0080009]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380] cytosol [GO:0005829]; nuclear body [GO:0016604]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA N6-methyladenosine methyltransferase complex [GO:0036396] RNA binding [GO:0003723] 0.96337 -2.653 FFTPPASKGNYSRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.9404 0 0 0 0 0 0 0 10.3302 0 0 0 0 Q69YQ0 CYTSA_HUMAN Cytospin-A (Renal carcinoma antigen NY-REN-22) (Sperm antigen with calponin homology and coiled-coil domains 1-like) (SPECC1-like protein) SPECC1L CYTSA KIAA0376 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; gap junction [GO:0005921]; microtubule organizing center [GO:0005815]; spindle [GO:0005819] 0.88621 -0.33971 IIESEQKGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.89025 0 0 0 0 0 Q69YW2 STUM_HUMAN Protein stum homolog STUM C1orf95 Homo sapiens (Human) membrane [GO:0016020] 0.90713 -0.73802 GASSSSGVVVQVREK 10.1029 9.92078 0 0 0 0 0 0 10.5496 0 0 9.68661 0 9.92939 0 10.0896 10.0088 9.41922 0 0 0 0 0 0 0 0 0 Q6A163 K1C39_HUMAN "Keratin, type I cytoskeletal 39 (Cytokeratin-39) (CK-39) (Keratin-39) (K39) (Type I hair keratin Ka35)" KRT39 KA35 Homo sapiens (Human) epithelial cell differentiation [GO:0030855]; intermediate filament organization [GO:0045109] cytosol [GO:0005829]; intermediate filament [GO:0005882] structural molecule activity [GO:0005198] 0.96021 -1.8101 ILCTKAENSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.94822 0 10.6703 0 0 Q6A1A2 PDPK2_HUMAN Putative 3-phosphoinositide-dependent protein kinase 2 (EC 2.7.11.1) (3-phosphoinositide-dependent protein kinase 2 pseudogene) PDPK2P PDPK2 Homo sapiens (Human) intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105] cytoplasm [GO:0005737]; membrane [GO:0016020] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.86138 0.093723 VSVPLRQACWWL 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.765 0 0 0 0 0 Q6AHZ1 Z518A_HUMAN Zinc finger protein 518A ZNF518A KIAA0335 ZNF518 Homo sapiens (Human) chromatin organization [GO:0006325]; regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.96882 -5.7821 EKAKPEDVR 0 0 0 0 0 0 0 0 0 10.8576 10.4634 10.4387 0 0 0 0 0 0 9.89542 9.43225 0 0 0 9.7417 0 0 9.59046 Q6AW86 Z324B_HUMAN Zinc finger protein 324B ZNF324B Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.9198 -0.93016 AFRERPALLHHQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2011 0 0 0 0 0 0 0 0 0 0 0 0 Q6AWC2 WWC2_HUMAN Protein WWC2 (BH-3-only member B) (WW domain-containing protein 2) WWC2 BOMB Homo sapiens (Human) cell migration [GO:0016477]; negative regulation of hippo signaling [GO:0035331]; negative regulation of organ growth [GO:0046621]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355]; regulation of hippo signaling [GO:0035330] cytoplasm [GO:0005737]; cytosol [GO:0005829] kinase binding [GO:0019900]; molecular adaptor activity [GO:0060090] 0.97006 -3.2453 AISSGEK 0 0 0 0 10.467 10.5423 0 8.91274 0 9.8324 9.58239 9.42143 10.6805 10.9126 10.2154 9.65793 9.93874 0 0 0 0 0 0 0 0 9.33121 0 Q6AZY7 SCAR3_HUMAN Scavenger receptor class A member 3 (Cellular stress response gene protein) SCARA3 CSR Homo sapiens (Human) response to oxidative stress [GO:0006979]; UV protection [GO:0009650] collagen trimer [GO:0005581]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139] scavenger receptor activity [GO:0005044] 0.51653 0.5955 GDPGSLGPLGPQGPQGQPGEAGPVGER 0 0 0 0 9.22016 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6AZZ1 TRI68_HUMAN E3 ubiquitin-protein ligase TRIM68 (EC 2.3.2.27) (RING finger protein 137) (RING-type E3 ubiquitin transferase TRIM68) (SSA protein SS-56) (SS-56) (Tripartite motif-containing protein 68) TRIM68 GC109 RNF137 SS56 Homo sapiens (Human) innate immune response [GO:0045087]; positive regulation of autophagy [GO:0010508]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of protein localization [GO:0032880]; regulation of viral entry into host cell [GO:0046596] cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; nuclear androgen receptor binding [GO:0050681]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.88976 -0.50043 LHPGMGLKGDLCERHGEK 0 13.1248 0 0 0 13.3112 13.7718 13.7225 0 9.38517 0 0 13.3386 13.5535 0 0 0 13.1675 0 0 10.5917 0 0 0 0 0 0 Q6B0I6 KDM4D_HUMAN Lysine-specific demethylase 4D (EC 1.14.11.66) (JmjC domain-containing histone demethylation protein 3D) (Jumonji domain-containing protein 2D) ([histone H3]-trimethyl-L-lysine(9) demethylase 4D) KDM4D JHDM3D JMJD2D Homo sapiens (Human) cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932] blood microparticle [GO:0072562]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861] chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; histone demethylase activity [GO:0032452]; histone H3K9 demethylase activity [GO:0032454]; histone H3K9me2/H3K9me3 demethylase activity [GO:0140684]; metal ion binding [GO:0046872] 0.95905 -1.9146 IIPPKEWKAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.96495 0 0 0 10.7152 0 0 0 0 0 0 Q6B0K9 HBM_HUMAN Hemoglobin subunit mu (Hemoglobin mu chain) (Mu-globin) HBM HBAP2 Homo sapiens (Human) cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744] haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833] heme binding [GO:0020037]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344] 0.85811 0.10011 FLTGVAVVLTEKYR 0 9.40825 0 0 0 0 0 0 9.04221 0 0 9.67046 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6B8I1 DS13A_HUMAN Dual specificity protein phosphatase 13 isoform A (DUSP13A) (EC 3.1.3.16) (EC 3.1.3.48) (Branching-enzyme interacting DSP) (Muscle-restricted DSP) (MDSP) DUSP13 BEDP DUSP13A MDSP Homo sapiens (Human) dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470] cytoplasm [GO:0005737] myosin phosphatase activity [GO:0017018]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138] 0.95485 -1.566 FELWKLGITHVLNAAHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2478 0 0 0 0 0 0 0 0 0 0 0 Q6BCY4 NB5R2_HUMAN NADH-cytochrome b5 reductase 2 (b5R.2) (EC 1.6.2.2) CYB5R2 Homo sapiens (Human) bicarbonate transport [GO:0015701]; sterol biosynthetic process [GO:0016126] endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleus [GO:0005634] "cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]" 0.84087 0.18388 IDNELVVR 0 0 0 0 0 0 0 0 0 0 0 0 10.2981 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6BDS2 BLT3A_HUMAN Bridge-like lipid transfer protein family member 3A (ICBP90-binding protein 1) (UHRF1-binding protein 1) (Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1) BLTP3A C6orf107 UHRF1BP1 Homo sapiens (Human) late endosome [GO:0005770] histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802] 0.96972 -3.4319 FTKNLSPDK 0 0 0 0 0 0 0 0 0 0 10.9564 0 0 0 0 0 0 0 0 0 10.936 0 0 0 0 0 10.5067 Q6BEB4 SP5_HUMAN Transcription factor Sp5 SP5 Homo sapiens (Human) bone morphogenesis [GO:0060349]; cellular response to organic cyclic compound [GO:0071407]; post-anal tail morphogenesis [GO:0036342]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.88458 -0.29867 SFTRSDELQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6348 0 Q6DCA0 AMERL_HUMAN AMMECR1-like protein AMMECR1L Homo sapiens (Human) 0.93318 -1.2656 IEFINEKGVKR 0 0 0 0 0 0 0 8.97814 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6DD88 ATLA3_HUMAN Atlastin-3 (EC 3.6.5.-) ATL3 Homo sapiens (Human) endoplasmic reticulum organization [GO:0007029]; Golgi organization [GO:0007030]; positive regulation of endoplasmic reticulum tubular network organization [GO:1903373]; protein homooligomerization [GO:0051260] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum tubular network [GO:0071782]; endoplasmic reticulum tubular network membrane [GO:0098826]; membrane [GO:0016020] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802] 0.96328 -2.6535 DAVVGRPSMDKKAQ 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2365 0 0 0 0 0 0 0 0 0 0 0 0 Q6DHV5 C2D2B_HUMAN Protein CC2D2B CC2D2B C10orf130 C10orf131 Homo sapiens (Human) non-motile cilium assembly [GO:1905515]; protein localization to ciliary transition zone [GO:1904491] ciliary transition zone [GO:0035869] 0.96965 -3.0757 EDSNEQNLK 9.83843 9.13376 10.7097 9.34818 0 0 10.0293 10.8981 10.4353 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6DHV7 ADAL_HUMAN Adenosine deaminase-like protein (EC 3.5.4.-) (Adenosine deaminase-like protein isoform 1) (N6-mAMP deaminase) (HsMAPDA) (N6-methyl-AMP aminohydrolase) ADAL ADAL1 Homo sapiens (Human) adenosine catabolic process [GO:0006154]; inosine biosynthetic process [GO:0046103]; nucleotide metabolic process [GO:0009117] cytosol [GO:0005829] adenosine deaminase activity [GO:0004000]; metal ion binding [GO:0046872]; N6-methyl-AMP deaminase activity [GO:0062154] 0.92598 -1.2131 TDFYSELPKVELHAHLNGSISSHTMKK 0 0 0 0 0 0 0 0 0 0 9.79722 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6DKI1 RL7L_HUMAN Ribosomal protein uL30-like (60S ribosomal protein L7-like 1) (Large ribosomal subunit protein uL30-like 1) RPL7L1 Homo sapiens (Human) "blastocyst formation [GO:0001825]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]" cytosolic large ribosomal subunit [GO:0022625]; nucleolus [GO:0005730] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.36683 0.74436 IVEPYVTWGFPNLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2613 0 0 Q6DKJ4 NXN_HUMAN Nucleoredoxin (EC 1.8.1.8) NXN NRX Homo sapiens (Human) cell differentiation [GO:0030154]; circulatory system development [GO:0072359]; in utero embryonic development [GO:0001701]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055] cytosol [GO:0005829]; nucleus [GO:0005634] thioredoxin-disulfide reductase activity [GO:0004791] 0.89876 -0.62306 QGRVEVLNDEDCR 0 0 0 0 0 0 0 0 11.4253 0 0 0 0 0 0 9.32508 0 0 0 0 0 0 0 0 0 0 0 Q6DKK2 TTC19_HUMAN "Tetratricopeptide repeat protein 19, mitochondrial (TPR repeat protein 19)" TTC19 Homo sapiens (Human) mitochondrial respiratory chain complex III assembly [GO:0034551]; mitotic cytokinesis [GO:0000281] centrosome [GO:0005813]; midbody [GO:0030496]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469] 0.80982 0.23185 LASIYAAQNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.66245 0 0 0 0 0 0 Q6DN12 MCTP2_HUMAN Multiple C2 and transmembrane domain-containing protein 2 MCTP2 Homo sapiens (Human) calcium-mediated signaling [GO:0019722]; regulation of neurotransmitter secretion [GO:0046928] cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; synaptic vesicle membrane [GO:0030672] calcium ion binding [GO:0005509] 0.96877 -3.5996 DNKKHEER 0 0 0 0 0 0 0 0 0 0 0 9.98042 0 0 0 0 0 9.93427 0 9.4873 10.7607 0 0 9.981 0 0 0 Q6DN14 MCTP1_HUMAN Multiple C2 and transmembrane domain-containing protein 1 MCTP1 Homo sapiens (Human) calcium-mediated signaling [GO:0019722]; negative regulation of cell migration [GO:0030336]; negative regulation of endocytosis [GO:0045806]; negative regulation of response to oxidative stress [GO:1902883]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of neurotransmitter secretion [GO:0046928] endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; recycling endosome [GO:0055037]; synaptic vesicle membrane [GO:0030672] calcium ion binding [GO:0005509] 0.96972 -5.1016 AEQGSTLRR 12.0234 0 9.33776 0 10.623 9.93764 9.37838 9.57323 0 0 0 0 0 0 9.13052 0 0 0 0 9.68946 0 0 0 0 0 10.2943 10.3232 Q6DN90 IQEC1_HUMAN IQ motif and SEC7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein) (BRAG2) IQSEC1 ARFGEP100 BRAG2 KIAA0763 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; dendritic spine development [GO:0060996]; positive regulation of focal adhesion disassembly [GO:0120183]; positive regulation of keratinocyte migration [GO:0051549]; regulation of ARF protein signal transduction [GO:0032012] intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleolus [GO:0005730]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021] guanyl-nucleotide exchange factor activity [GO:0005085]; lipid binding [GO:0008289] 0.21778 0.88782 ARDTEPQTALHGMDHRK 0 0 0 0 0 0 0 0 0 10.3103 0 0 0 8.63176 0 8.80713 0 0 8.54624 0 0 0 0 0 12.1878 0 9.86448 Q6DT37 MRCKG_HUMAN Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42-binding protein kinase gamma) (DMPK-like gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (MRCK gamma) (MRCKG) (Myotonic dystrophy protein kinase-like gamma) (Myotonic dystrophy protein kinase-like alpha) CDC42BPG DMPK2 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; actomyosin structure organization [GO:0031032]; peptidyl-threonine phosphorylation [GO:0018107]; protein phosphorylation [GO:0006468] cell leading edge [GO:0031252]; centriolar satellite [GO:0034451]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829] ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.92604 -0.95918 LPEMLRDK 0 11.7309 0 0 0 0 9.51993 0 9.45674 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6E213 AWAT2_HUMAN Acyl-CoA wax alcohol acyltransferase 2 (EC 2.3.1.75) (11-cis-specific retinyl-ester synthase) (11-cis-RE-synthase) (Acyl-CoA retinol O-fatty-acyltransferase) (ARAT) (Retinol O-fatty-acyltransferase) (EC 2.3.1.76) (Diacylglycerol O-acyltransferase 2-like protein 4) (Diacylglycerol O-acyltransferase candidate 4) (hDC4) (Long-chain-alcohol O-fatty-acyltransferase 2) (Multifunctional O-acyltransferase) (Wax synthase) (hWS) AWAT2 DC4 DGAT2L4 MFAT WS Homo sapiens (Human) acylglycerol acyl-chain remodeling [GO:0036155]; lipid metabolic process [GO:0006629]; monoacylglycerol biosynthetic process [GO:0006640]; retinoid metabolic process [GO:0001523]; wax biosynthetic process [GO:0010025] endoplasmic reticulum membrane [GO:0005789] 2-acylglycerol O-acyltransferase activity [GO:0003846]; arachidoyl-CoA:1-dodecanol O-acyltransferase activity [GO:0102966]; long-chain-alcohol O-fatty-acyltransferase activity [GO:0047196]; retinol O-fatty-acyltransferase activity [GO:0050252] 0.90822 -0.74029 HYSDYFPLK 0 0 0 0 0 0 0 0 0 0 0 10.6129 0 0 0 0 0 0 0 0 0 10.4843 0 0 0 0 0 Q6ECI4 ZN470_HUMAN Zinc finger protein 470 (Chondrogenesis zinc finger protein 1) (CZF-1) ZNF470 CZF1 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nuclear body [GO:0016604]; nucleoplasm [GO:0005654] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96934 -3.995 AFTDHIGLIQHK 0 0 0 0 0 0 10.796 0 0 0 10.3908 9.34638 0 0 10.7399 0 0 0 0 0 0 0 0 0 0 0 0 Q6EEV6 SUMO4_HUMAN Small ubiquitin-related modifier 4 (SUMO-4) (Small ubiquitin-like protein 4) SUMO4 SMT3H4 Homo sapiens (Human) cellular response to oxidative stress [GO:0034599]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of DNA binding [GO:0043388]; protein sumoylation [GO:0016925]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of protein localization to nucleus [GO:1900180] nucleus [GO:0005634]; SUMO ligase complex [GO:0106068] protein tag [GO:0031386]; ubiquitin-like protein ligase binding [GO:0044389] 0.0097561 1.8092 VAGQDGSVVQFK 0 0 0 0 0 0 9.46397 9.51019 9.63797 0 0 10.0189 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6EMB2 TTLL5_HUMAN Tubulin polyglutamylase TTLL5 (EC 6.3.2.-) (SRC1 and TIF2-associated modulatory protein) (STAMP protein) (Tubulin--tyrosine ligase-like protein 5) TTLL5 KIAA0998 STAMP Homo sapiens (Human) microtubule cytoskeleton organization [GO:0000226]; protein polyglutamylation [GO:0018095]; retina development in camera-type eye [GO:0060041] centrosome [GO:0005813]; cilium [GO:0005929]; cytosol [GO:0005829]; microtubule [GO:0005874]; nucleus [GO:0005634]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; tubulin binding [GO:0015631]; tubulin-glutamic acid ligase activity [GO:0070740] 0.95278 -1.4682 NLVGSAREK 0 0 0 0 0 0 0 0 0 9.62273 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6F5E7 TR3N_HUMAN Putative uncharacterized protein TXNRD3NB (Thioredoxin reductase 2 intronic transcript 1) (Thioredoxin reductase 3 intronic transcript 1) (Thioredoxin reductase 3 neighbor gene protein) (TXNRD3 neighbor gene protein) (Thioredoxin reductase 3 new transcript 1) TXNRD3NB TR2IT1 TXNRD3IT1 TXNRD3NT1 Homo sapiens (Human) 0.93155 -1.254 AKCLSGEPGQPEGKGQETYPGPGK 17.8768 0 17.5946 16.0129 16.4219 0 17.9807 0 18.0053 16.8612 0 0 0 16.1473 0 16.4214 16.4977 0 0 0 12.9541 0 0 13.0594 12.5824 0 0 Q6GPH4 XAF1_HUMAN XIAP-associated factor 1 (BIRC4-binding protein) XAF1 BIRC4BP XIAPAF1 Homo sapiens (Human) apoptotic process [GO:0006915]; negative regulation of type I interferon production [GO:0032480]; response to interferon-beta [GO:0035456] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] molecular sequestering activity [GO:0140313]; zinc ion binding [GO:0008270] 0.67988 0.39198 ETMEEHCKLEHQQVGCTMCQQSMQK 13.1589 13.0951 13.2698 9.9617 10.7575 9.98897 0 13.5068 13.8483 0 13.7872 0 9.57094 8.65051 8.83229 9.59662 0 9.68266 0 0 0 0 0 0 0 0 0 Q6GQQ9 OTU7B_HUMAN OTU domain-containing protein 7B (EC 3.4.19.12) (Cellular zinc finger anti-NF-kappa-B protein) (Cezanne) (Zinc finger A20 domain-containing protein 1) (Zinc finger protein Cezanne) OTUD7B ZA20D1 Homo sapiens (Human) adaptive immune response [GO:0002250]; in utero embryonic development [GO:0001701]; mucosal immune response [GO:0002385]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein deubiquitination [GO:0016579]; protein deubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0071947]; protein K11-linked deubiquitination [GO:0035871]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] cysteine-type deubiquitinase activity [GO:0004843]; cysteine-type peptidase activity [GO:0008234]; DNA binding [GO:0003677]; K48-linked deubiquitinase activity [GO:1990380]; K63-linked polyubiquitin modification-dependent protein binding [GO:0070530]; zinc ion binding [GO:0008270] 0.95534 -1.5559 EPDGELLVHRF 0 0 0 0 0 0 0 0 0 10.1012 0 0 0 0 0 0 0 0 10.1355 0 0 0 0 0 9.89854 0 0 Q6GTS8 P20D1_HUMAN N-fatty-acyl-amino acid synthase/hydrolase PM20D1 (EC 3.5.1.114) (EC 3.5.1.14) (Peptidase M20 domain-containing protein 1) PM20D1 Homo sapiens (Human) adaptive thermogenesis [GO:1990845]; amide biosynthetic process [GO:0043604]; amide catabolic process [GO:0043605]; amino acid metabolic process [GO:0006520]; cellular lipid metabolic process [GO:0044255]; energy homeostasis [GO:0097009]; fatty acid metabolic process [GO:0006631]; proteolysis [GO:0006508] extracellular exosome [GO:0070062]; extracellular region [GO:0005576] "aminoacylase activity [GO:0004046]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; peptidase activity [GO:0008233]" 0.84933 0.16221 FYPIYIQPEDFK 0 0 9.45648 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6GYQ0 RGPA1_HUMAN Ral GTPase-activating protein subunit alpha-1 (GAP-related-interacting partner to E12) (GRIPE) (GTPase-activating Rap/Ran-GAP domain-like 1) (Tuberin-like protein 1) (p240) RALGAPA1 GARNL1 KIAA0884 TULIP1 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056] cytoplasm [GO:0005737]; nucleus [GO:0005634] GTPase activator activity [GO:0005096]; protein heterodimerization activity [GO:0046982] 0.2861 0.82609 DEPSGPAR 0 0 0 10.5557 9.69883 13.5864 0 0 0 0 0 0 11.0314 11.2346 10.631 12.3657 12.1897 8.52654 0 0 0 9.71937 0 0 10.4937 0 0 Q6H3X3 ULBP5_HUMAN UL-16 binding protein 5 (Retinoic acid early transcript 1G protein) RAET1G ULBP5 Homo sapiens (Human) "antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent [GO:0002486]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; immune response [GO:0006955]; natural killer cell mediated cytotoxicity [GO:0042267]; positive regulation of natural killer cell cytokine production [GO:0002729]; positive regulation of T cell mediated cytotoxicity [GO:0001916]" endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886] natural killer cell lectin-like receptor binding [GO:0046703] 0.87019 0.053959 VLWSDSYQIAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3005 0 0 Q6H8Q1 ABLM2_HUMAN Actin-binding LIM protein 2 (abLIM-2) (Actin-binding LIM protein family member 2) ABLIM2 KIAA1808 Homo sapiens (Human) cytoskeleton organization [GO:0007010]; lamellipodium assembly [GO:0030032] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737] actin filament binding [GO:0051015]; metal ion binding [GO:0046872] 0.86969 0.052082 SPQHYSRPGSESGR 0 0 0 0 0 0 0 0 0 0 0 9.93702 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6H9L7 ISM2_HUMAN Isthmin-2 (Thrombospondin and AMOP domain-containing isthmin-like protein 1) (Thrombospondin type-1 domain-containing protein 3) ISM2 TAIL1 THSD3 PSEC0137 Homo sapiens (Human) extracellular region [GO:0005576] 0.92367 -1.1617 APGEKGEEK 0 11.2089 0 0 0 0 11.5524 0 0 9.78578 0 0 0 10.2889 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6I9Y2 THOC7_HUMAN THO complex subunit 7 homolog (Functional spliceosome-associated protein 24) (fSAP24) (Ngg1-interacting factor 3-like protein 1-binding protein 1) (NIF3L1-binding protein 1) (hTREX30) THOC7 NIF3L1BP1 Homo sapiens (Human) mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380]; viral mRNA export from host cell nucleus [GO:0046784] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; THO complex [GO:0000347]; THO complex part of transcription export complex [GO:0000445]; transcription export complex [GO:0000346] RNA binding [GO:0003723] 0.018868 1.6517 GAVTDDEVIRK 0 0 0 0 0 0 0 0 0 0 10.0264 9.69798 0 0 9.64295 0 0 0 0 0 0 0 0 0 0 0 0 Q6IA69 NADE_HUMAN Glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing]) (NAD(+) synthetase) NADSYN1 Homo sapiens (Human) 'de novo' NAD biosynthetic process [GO:0034627]; NAD biosynthetic process [GO:0009435] cytoplasm [GO:0005737]; cytosol [GO:0005829] ATP binding [GO:0005524]; glutaminase activity [GO:0004359]; NAD+ synthase (glutamine-hydrolyzing) activity [GO:0003952] 0.8976 -0.62695 ILTTCYMASK 0 0 0 0 0 0 0 0 12.8925 11.7507 0 9.6989 0 0 0 0 0 0 9.93278 0 0 0 0 8.48236 0 0 0 Q6IAN0 DRS7B_HUMAN Dehydrogenase/reductase SDR family member 7B (EC 1.1.-.-) (Short-chain dehydrogenase/reductase family 32C member 1) (Protein SDR32C1) DHRS7B SDR32C1 CGI-93 UNQ212/PRO238 Homo sapiens (Human) adipose tissue development [GO:0060612]; brown fat cell differentiation [GO:0050873]; ether lipid biosynthetic process [GO:0008611]; inflammatory response [GO:0006954]; negative regulation of protein binding [GO:0032091]; neutrophil differentiation [GO:0030223]; phosphatidylcholine biosynthetic process [GO:0006656]; regulation of cold-induced thermogenesis [GO:0120161] endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; nucleus [GO:0005634]; peroxisomal membrane [GO:0005778]; transcription regulator complex [GO:0005667] acylglycerone-phosphate reductase activity [GO:0000140]; DNA-binding transcription factor binding [GO:0140297]; transcription corepressor activity [GO:0003714] 0.96893 -3.8841 LLQWVRGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.04193 8.8041 0 0 0 0 0 0 Q6IB77 GLYAT_HUMAN Glycine N-acyltransferase (EC 2.3.1.13) (Acyl-CoA:glycine N-acyltransferase) (AAc) (Aralkyl acyl-CoA N-acyltransferase) (Aralkyl acyl-CoA:amino acid N-acyltransferase) (Benzoyl-coenzyme A:glycine N-acyltransferase) (Glycine N-benzoyltransferase) (EC 2.3.1.71) (HRP-1(CLP)) GLYAT ACGNAT CAT GAT Homo sapiens (Human) acyl-CoA metabolic process [GO:0006637]; benzoyl-CoA metabolic process [GO:1901787]; glycine metabolic process [GO:0006544]; monocarboxylic acid metabolic process [GO:0032787]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] acyltransferase activity [GO:0016746]; glycine N-acyltransferase activity [GO:0047961]; glycine N-benzoyltransferase activity [GO:0047962] 0.84821 0.1542 MMLPLQGAQMLQMLEK 0 0 0 0 0 0 10.9307 0 11.245 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6IC98 GRAM4_HUMAN GRAM domain-containing protein 4 (Death-inducing protein) GRAMD4 DIP KIAA0767 Homo sapiens (Human) apoptotic process [GO:0006915]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280] endoplasmic reticulum membrane [GO:0005789]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739] 0.83584 0.18813 TEEQMAQQPPK 0 0 0 0 10.2219 0 0 0 0 0 0 0 0 8.87587 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ICB0 DESI1_HUMAN Desumoylating isopeptidase 1 (DeSI-1) (EC 3.4.-.-) (PPPDE peptidase domain-containing protein 2) (Polyubiquitinated substrate transporter) (POST) DESI1 FAM152B PPPDE2 Homo sapiens (Human) protein desumoylation [GO:0016926]; protein export from nucleus [GO:0006611]; protein modification by small protein removal [GO:0070646]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434] cytosol [GO:0005829]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] deSUMOylase activity [GO:0016929]; identical protein binding [GO:0042802]; importin-alpha family protein binding [GO:0061676] 0.91537 -0.80611 MEPPNLYPVKLYVYDLSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3425 0 0 0 0 0 0 0 0 0 0 Q6IE37 OVOS1_HUMAN Ovostatin homolog 1 OVOS1 Homo sapiens (Human) negative regulation of peptidase activity [GO:0010466] extracellular space [GO:0005615] serine-type endopeptidase inhibitor activity [GO:0004867] 0.95918 -1.8637 GGGLAAADDFLYLECCK 0 0 0 9.77075 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6IE81 JADE1_HUMAN Protein Jade-1 (Jade family PHD finger protein 1) (PHD finger protein 17) JADE1 KIAA1807 PHF17 Homo sapiens (Human) apoptotic process [GO:0006915]; chromatin remodeling [GO:0006338]; histone H4-K12 acetylation [GO:0043983]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; histone modification [GO:0016570]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; regulation of cell cycle [GO:0051726]; regulation of cell growth [GO:0001558]; regulation of DNA biosynthetic process [GO:2000278]; regulation of DNA replication [GO:0006275]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; histone acetyltransferase complex [GO:0000123]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] metal ion binding [GO:0046872]; transcription coactivator activity [GO:0003713] 0.92446 -1.0406 EQDVLFRR 0 0 0 0 0 0 0 0 0 0 0 0 0 8.94875 8.84706 0 0 0 0 0 0 0 0 9.47373 0 0 8.94799 Q6IEY1 OR4F3_HUMAN Olfactory receptor 4F3/4F16/4F29 (Olfactory receptor OR1-1) OR4F3; OR4F16; OR4F29 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.93947 -1.3234 QLVIYKRIS 0 0 0 0 0 0 0 0 0 0 0 10.5818 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6IF82 O4A47_HUMAN Olfactory receptor 4A47 (Olfactory receptor OR11-113) OR4A47 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.6766 0.39371 DLISSST 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7.87744 0 8.44083 8.59738 0 0 0 0 Q6IMN6 CAPR2_HUMAN Caprin-2 (C1q domain-containing protein 1) (Cytoplasmic activation/proliferation-associated protein 2) (Gastric cancer multidrug resistance-associated protein) (Protein EEG-1) (RNA granule protein 140) CAPRIN2 C1QDC1 EEG1 KIAA1873 RNG140 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of cell growth [GO:0030308]; negative regulation of translation [GO:0017148]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription by RNA polymerase II [GO:0045944] centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] metal ion binding [GO:0046872]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102] 0.96211 -2.4759 AGYVQEEQK 0 0 0 0 0 0 0 0 10.7936 0 10.9878 0 0 0 0 0 0 0 0 0 10.6755 9.50339 0 0 0 0 0 Q6IN85 P4R3A_HUMAN Serine/threonine-protein phosphatase 4 regulatory subunit 3A (SMEK homolog 1) PPP4R3A KIAA2010 PP4R3A SMEK1 MSTP033 Homo sapiens (Human) DNA damage response [GO:0006974]; protein dephosphorylation [GO:0006470] cytosol [GO:0005829]; microtubule organizing center [GO:0005815]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; protein phosphatase 4 complex [GO:0030289] protein phosphatase activator activity [GO:0072542] 0.95917 -1.7371 ALEDVDYVQTFK 0 0 9.80071 0 0 0 0 0 0 8.71802 11.4557 0 0 0 10.056 10.895 0 0 0 0 0 0 0 0 0 0 0 Q6IPM2 IQCE_HUMAN IQ domain-containing protein E IQCE KIAA1023 Homo sapiens (Human) limb morphogenesis [GO:0035108] ciliary membrane [GO:0060170]; cilium [GO:0005929] 0.96906 -4.4859 DLKEERTALQEQLLQR 0 0 0 0 0 0 0 0 0 0 15.4905 0 0 10.2406 0 0 0 10.5308 0 0 0 0 0 0 0 9.06907 0 Q6IPT4 NB5R5_HUMAN NADH-cytochrome b5 reductase-like (EC 1.6.2.2) CYB5RL Homo sapiens (Human) bicarbonate transport [GO:0015701] endoplasmic reticulum membrane [GO:0005789]; nucleoplasm [GO:0005654] "cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]" 0.8602 0.092597 TFLQEQARFWNVR 8.87461 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6IPX3 TCAL6_HUMAN Transcription elongation factor A protein-like 6 (TCEA-like protein 6) (Transcription elongation factor S-II protein-like 6) TCEAL6 Homo sapiens (Human) nucleus [GO:0005634] 0.026549 1.5397 GGGRGQR 0 10.151 0 0 9.69406 0 10.1088 10.1904 10.2105 10.5185 0 10.2181 0 12.5824 0 0 9.76183 9.78903 0 9.53269 0 0 0 0 0 0 10.2204 Q6IQ19 CCSAP_HUMAN "Centriole, cilia and spindle-associated protein" CCSAP C1orf96 CSAP Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; mitotic spindle microtubule depolymerization [GO:1990755]; regulation of embryonic development [GO:0045995]; regulation of mitotic spindle assembly [GO:1901673] axon [GO:0030424]; axoneme [GO:0005930]; centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary transition zone [GO:0035869]; cilium [GO:0005929]; mitotic spindle [GO:0072686]; mitotic spindle astral microtubule [GO:0061673]; spindle [GO:0005819] microtubule binding [GO:0008017] 0.76494 0.27982 DVEDKPEQQTR 0 0 0 0 0 0 0 0 0 9.82512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6IQ20 NAPEP_HUMAN N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (N-acyl phosphatidylethanolamine phospholipase D) (NAPE-PLD) (NAPE-hydrolyzing phospholipase D) (EC 3.1.4.54) NAPEPLD C7orf18 Homo sapiens (Human) host-mediated regulation of intestinal microbiota composition [GO:0048874]; N-acylethanolamine metabolic process [GO:0070291]; N-acylphosphatidylethanolamine metabolic process [GO:0070292]; phospholipid catabolic process [GO:0009395]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of inflammatory response [GO:0050729]; retinoid metabolic process [GO:0001523]; temperature homeostasis [GO:0001659] cytoplasm [GO:0005737]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane-bounded organelle [GO:0043227]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; photoreceptor outer segment membrane [GO:0042622] bile acid binding [GO:0032052]; identical protein binding [GO:0042802]; N-acetylphosphatidylethanolamine-hydrolysing phospholipase activity [GO:0102200]; N-acylphosphatidylethanolamine-specific phospholipase D activity [GO:0070290]; zinc ion binding [GO:0008270] 0.90927 -0.74599 NPSIPNVLRWLIMEK 0 0 0 0 0 0 0 0 0 10.2158 0 10.4977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6IQ21 ZN770_HUMAN Zinc finger protein 770 ZNF770 Homo sapiens (Human) nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.88533 -0.33761 ENIRTRHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0161 0 0 0 0 0 0 0 0 10.0325 Q6IQ23 PKHA7_HUMAN Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7) PLEKHA7 Homo sapiens (Human) cell-cell adhesion mediated by cadherin [GO:0044331]; epithelial cell-cell adhesion [GO:0090136]; pore complex assembly [GO:0046931]; zonula adherens maintenance [GO:0045218] cell junction [GO:0030054]; centrosome [GO:0005813]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; pore complex [GO:0046930]; zonula adherens [GO:0005915] delta-catenin binding [GO:0070097] 0.96894 -4.5457 DLEYLDLK 10.1195 10.0385 9.76456 0 0 0 0 0 0 9.4651 9.33235 0 0 0 0 0 0 0 0 11.4184 11.3514 0 0 11.5631 0 0 11.5913 Q6IQ26 DEN5A_HUMAN DENN domain-containing protein 5A (Rab6-interacting protein 1) (Rab6IP1) DENND5A KIAA1091 RAB6IP1 Homo sapiens (Human) "negative regulation of neuron projection development [GO:0010977]; retrograde transport, endosome to Golgi [GO:0042147]" cytosol [GO:0005829]; Golgi membrane [GO:0000139]; trans-Golgi network [GO:0005802] guanyl-nucleotide exchange factor activity [GO:0005085]; small GTPase binding [GO:0031267] 0.96734 -2.824 IGQGKYEPGFFPK 0 0 0 0 0 0 9.01589 0 9.14957 0 0 0 0 0 0 9.95559 0 0 0 0 0 0 0 0 0 0 0 Q6IQ49 SDE2_HUMAN Splicing regulator SDE2 (Replication stress response regulator SDE2) SDE2 C1orf55 Homo sapiens (Human) "cell division [GO:0051301]; cellular response to UV [GO:0034644]; DNA replication [GO:0006260]; endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000479]; mitotic G1 DNA damage checkpoint signaling [GO:0031571]; mRNA cis splicing, via spliceosome [GO:0045292]; protein processing [GO:0016485]; protein ubiquitination [GO:0016567]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] damaged DNA binding [GO:0003684]; snoRNA binding [GO:0030515] 0.96321 -2.6407 SQTDRGASAGKR 0 0 0 0 0 0 0 0 0 12.1788 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6IQ55 TTBK2_HUMAN Tau-tubulin kinase 2 (EC 2.7.11.1) TTBK2 KIAA0847 Homo sapiens (Human) cerebellar granular layer development [GO:0021681]; cerebellar granule cell precursor tangential migration [GO:0021935]; cerebellum development [GO:0021549]; cilium assembly [GO:0060271]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of microtubule binding [GO:1904527]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of protein localization to microtubule [GO:1902817]; peptidyl-serine phosphorylation [GO:0018105]; regulation of cell migration [GO:0030334]; signal transduction [GO:0007165]; smoothened signaling pathway [GO:0007224] centriole [GO:0005814]; ciliary basal body [GO:0036064]; ciliary transition zone [GO:0035869]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634] ATP binding [GO:0005524]; kinesin binding [GO:0019894]; microtubule plus-end binding [GO:0051010]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321] 0.96117 -2.0235 AGRPHHDQRSSSPHLGR 0 0 0 0 0 0 0 0 0 0 16.0758 0 0 0 0 0 0 0 0 0 0 0 12.2782 0 9.60105 12.1925 0 Q6ISU1 PTCRA_HUMAN Pre T-cell antigen receptor alpha (pT-alpha) (pTa) (pT-alpha-TCR) PTCRA Homo sapiens (Human) negative regulation of thymocyte apoptotic process [GO:0070244] membrane [GO:0016020] 0.84397 0.13681 LHPATETGGREATSSPRPQPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.51029 0 0 0 0 0 0 Q6IV72 ZN425_HUMAN Zinc finger protein 425 ZNF425 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122] cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.96148 -2.5707 EFPCGECKK 0 0 0 0 0 0 10.8315 0 0 0 8.14797 9.44849 0 0 0 0 0 0 0 0 0 0 0 0 0 10.159 0 Q6JBY9 CPZIP_HUMAN CapZ-interacting protein (Protein kinase substrate CapZIP) (RCSD domain-containing protein 1) RCSD1 CAPZIP Homo sapiens (Human) "cellular hyperosmotic response [GO:0071474]; protein localization to endosome [GO:0036010]; retrograde transport, endosome to Golgi [GO:0042147]; skeletal muscle contraction [GO:0003009]" actin filament [GO:0005884]; cytosol [GO:0005829]; early endosome [GO:0005769]; WASH complex [GO:0071203] actin filament binding [GO:0051015]; phosphatidylinositol phosphate binding [GO:1901981]; retromer complex binding [GO:1905394] 0.96969 -3.9538 ATEEAKNGEK 0 0 0 0 0 0 0 0 0 0 10.0794 0 0 0 0 0 9.24781 0 0 0 0 0 0 0 0 0 0 Q6JQN1 ACD10_HUMAN Acyl-CoA dehydrogenase family member 10 (ACAD-10) (EC 1.3.99.-) ACAD10 Homo sapiens (Human) fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539] cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660] 0.95406 -1.5175 AEITAEGFLR 11.6969 0 0 0 0 0 0 0 8.46773 10.8762 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5029 0 0 Q6JVE6 LCN10_HUMAN Epididymal-specific lipocalin-10 LCN10 Homo sapiens (Human) extracellular region [GO:0005576] small molecule binding [GO:0036094] 0.92261 -0.94484 KLGASVVKVNK 0 0 0 10.3026 0 10.5493 0 0 14.2136 0 0 0 0 0 0 0 9.59634 0 0 0 0 0 0 0 0 0 0 Q6K0P9 IFIX_HUMAN Pyrin and HIN domain-containing protein 1 (Interferon-inducible protein X) PYHIN1 IFIX Homo sapiens (Human) "activation of innate immune response [GO:0002218]; cell cycle [GO:0007049]; cellular response to interferon-alpha [GO:0035457]; cellular response to interferon-beta [GO:0035458]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:1902164]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein destabilization [GO:0031648]; protein stabilization [GO:0050821]" nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991] double-stranded DNA binding [GO:0003690]; ubiquitin protein ligase binding [GO:0031625] 0.93015 -1.2373 GAEETLGPQK 0 0 0 0 0 0 0 10.3376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6KB66 K2C80_HUMAN "Keratin, type II cytoskeletal 80 (Cytokeratin-80) (CK-80) (Keratin-80) (K80) (Type-II keratin Kb20)" KRT80 KB20 Homo sapiens (Human) keratinization [GO:0031424] cytoplasm [GO:0005737]; cytosol [GO:0005829]; intermediate filament [GO:0005882]; intermediate filament cytoskeleton [GO:0045111]; keratin filament [GO:0045095] structural constituent of skin epidermis [GO:0030280] 0.91614 -0.80952 LDPAVQQLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.63465 0 0 0 0 0 0 0 Q6KC79 NIPBL_HUMAN Nipped-B-like protein (Delangin) (SCC2 homolog) NIPBL IDN3 SCC2 Homo sapiens (Human) brain development [GO:0007420]; cellular response to X-ray [GO:0071481]; cognition [GO:0050890]; developmental growth [GO:0048589]; digestive tract development [GO:0048565]; DNA damage response [GO:0006974]; ear morphogenesis [GO:0042471]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic forelimb morphogenesis [GO:0035115]; embryonic viscerocranium morphogenesis [GO:0048703]; establishment of mitotic sister chromatid cohesion [GO:0034087]; establishment of protein localization to chromatin [GO:0071169]; external genitalia morphogenesis [GO:0035261]; eye morphogenesis [GO:0048592]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forelimb morphogenesis [GO:0035136]; gallbladder development [GO:0061010]; heart morphogenesis [GO:0003007]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; metanephros development [GO:0001656]; mitotic cohesin loading [GO:0061780]; mitotic sister chromatid cohesion [GO:0007064]; mitotic sister chromatid segregation [GO:0000070]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; outflow tract morphogenesis [GO:0003151]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of neuron migration [GO:2001224]; positive regulation of ossification [GO:0045778]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization [GO:0008104]; regulation of developmental growth [GO:0048638]; regulation of embryonic development [GO:0045995]; regulation of hair cycle [GO:0042634]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; sensory perception of sound [GO:0007605]; somatic stem cell population maintenance [GO:0035019]; uterus morphogenesis [GO:0061038] chromatin [GO:0000785]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; integrator complex [GO:0032039]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Scc2-Scc4 cohesin loading complex [GO:0090694]; SMC loading complex [GO:0032116] chromatin binding [GO:0003682]; chromo shadow domain binding [GO:0070087]; cohesin loader activity [GO:0061775]; histone deacetylase binding [GO:0042826]; mediator complex binding [GO:0036033]; promoter-specific chromatin binding [GO:1990841] 0.96949 -4.6328 AEFPSYLLGGR 0 0 0 0 0 0 0 8.85428 10.9259 0 9.97757 0 0 0 0 9.92864 9.29767 0 8.24474 9.6451 0 0 0 0 11.1493 14.2519 0 Q6KCM7 SCMC2_HUMAN Mitochondrial adenyl nucleotide antiporter SLC25A25 (Mitochondrial ATP-Mg/Pi carrier protein 3) (Mitochondrial Ca(2+)-dependent solute carrier protein 3) (Short calcium-binding mitochondrial carrier protein 2) (SCaMC-2) (Solute carrier family 25 member 25) SLC25A25 APC3 KIAA1896 MCSC3 SCAMC2 UNQ549/PRO1106 Homo sapiens (Human) adipose tissue development [GO:0060612]; ADP transport [GO:0015866]; ATP metabolic process [GO:0046034]; ATP transport [GO:0015867]; calcium ion transmembrane transport [GO:0070588]; camera-type eye development [GO:0043010]; cellular respiration [GO:0045333]; multicellular organism growth [GO:0035264]; response to activity [GO:0014823]; response to dietary excess [GO:0002021]; response to food [GO:0032094] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] ATP transmembrane transporter activity [GO:0005347]; ATP:inorganic phosphate antiporter activity [GO:0140987]; calcium ion binding [GO:0005509] 0.89869 -0.62488 ISEQQAEKILKSMDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.07149 0 0 0 0 0 0 10.5637 0 0 0 0 Q6KF10 GDF6_HUMAN Growth/differentiation factor 6 (GDF-6) (Bone morphogenetic protein 13) (BMP-13) (Growth/differentiation factor 16) GDF6 BMP13 GDF16 Homo sapiens (Human) activin receptor signaling pathway [GO:0032924]; apoptotic process [GO:0006915]; BMP signaling pathway [GO:0030509]; cell migration involved in metanephros development [GO:0035788]; fat cell differentiation [GO:0045444]; metanephros development [GO:0001656]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; retinal cell apoptotic process [GO:1990009]; SMAD protein signal transduction [GO:0060395] extracellular space [GO:0005615] cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802] 0.89744 -0.54762 NLFAEMR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.78051 8.74457 0 0 0 0 0 0 0 0 0 12.8062 Q6L8Q7 PDE12_HUMAN "2',5'-phosphodiesterase 12 (2'-PDE) (2-PDE) (EC 3.1.4.-) (Mitochondrial deadenylase) (EC 3.1.13.4)" PDE12 Homo sapiens (Human) "antiviral innate immune response [GO:0140374]; cellular response to dsRNA [GO:0071359]; cellular response to interferon-alpha [GO:0035457]; cellular response to type II interferon [GO:0071346]; defense response to virus [GO:0051607]; mitochondrial mRNA catabolic process [GO:0000958]; mRNA processing [GO:0006397]; negative regulation of oxidative phosphorylation [GO:0090324]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of viral genome replication [GO:0045070]; regulation of mitochondrial mRNA stability [GO:0044528]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]" cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] 3'-5'-RNA exonuclease activity [GO:0000175]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; oligoribonucleotidase activity [GO:0034611]; poly(A)-specific ribonuclease activity [GO:0004535] 0.22812 0.86371 LSLSFALADGSHK 0 0 0 0 9.63385 0 0 0 0 0 0 12.4983 0 0 10.6794 11.0856 0 11.8633 10.9943 11.455 0 0 10.6035 10.3347 0 0 0 Q6L9W6 B4GN3_HUMAN "Beta-1,4-N-acetylgalactosaminyltransferase 3 (B4GalNAcT3) (Beta4GalNAc-T3) (Beta4GalNAcT3) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase III) (N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2) (NGalNAc-T2)" B4GALNT3 Homo sapiens (Human) Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; intracellular membrane-bounded organelle [GO:0043231] acetylgalactosaminyltransferase activity [GO:0008376]; N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity [GO:0033842] 0.94038 -1.3086 CFYQENAYYQDR 0 12.8503 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6MZM0 HPHL1_HUMAN Ferroxidase HEPHL1 (EC 1.16.3.1) (Hephaestin-like protein 1) HEPHL1 Homo sapiens (Human) copper ion transport [GO:0006825]; intracellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826] plasma membrane [GO:0005886] copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322] 0.85054 0.15882 ILWDYAPQGYNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.21924 0 Q6MZP7 LIN54_HUMAN Protein lin-54 homolog (CXC domain-containing protein 1) LIN54 CXCDC1 KIAA2037 Homo sapiens (Human) cell cycle [GO:0007049]; nucleosome organization [GO:0034728]; regulation of DNA-templated transcription [GO:0006355] nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription repressor complex [GO:0090571] metal ion binding [GO:0046872]; minor groove of adenine-thymine-rich DNA binding [GO:0003680]; transcription regulatory region nucleic acid binding [GO:0001067] 0.020595 1.6176 EVAEATCNCLLAQAEQADKK 0 0 0 0 0 0 0 10.8195 0 0 0 0 0 0 0 0 0 10.132 0 0 12.0851 0 0 0 0 0 0 Q6MZZ7 CAN13_HUMAN Calpain-13 (EC 3.4.22.-) (Calcium-activated neutral proteinase 13) (CANP 13) CAPN13 Homo sapiens (Human) proteolysis [GO:0006508] cytoplasm [GO:0005737] calcium-dependent cysteine-type endopeptidase activity [GO:0004198] 0.8979 -0.55283 CLFVRPR 0 0 0 0 0 8.97777 0 0 0 0 0 0 0 0 10.6162 0 0 0 0 0 0 0 0 0 0 0 0 Q6N021 TET2_HUMAN Methylcytosine dioxygenase TET2 (EC 1.14.11.80) TET2 KIAA1546 Nbla00191 Homo sapiens (Human) 5-methylcytosine catabolic process [GO:0006211]; cell cycle [GO:0007049]; chromatin organization [GO:0006325]; DNA demethylation [GO:0080111]; leukocyte differentiation [GO:0002521]; myeloid cell differentiation [GO:0030099]; oxidative demethylation [GO:0070989]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein O-linked glycosylation [GO:0006493]; response to organic cyclic compound [GO:0014070] chromosome [GO:0005694]; nucleus [GO:0005634] DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; methylcytosine dioxygenase activity [GO:0070579]; zinc ion binding [GO:0008270] 0.92434 -0.95136 EGSFFGQTK 0 0 0 0 0 0 10.4919 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.86658 0 Q6N022 TEN4_HUMAN Teneurin-4 (Ten-4) (Protein Odd Oz/ten-m homolog 4) (Tenascin-M4) (Ten-m4) (Teneurin transmembrane protein 4) TENM4 KIAA1302 ODZ4 TNM4 Homo sapiens (Human) cardiac cell fate specification [GO:0060912]; cardiac muscle cell proliferation [GO:0060038]; central nervous system myelin formation [GO:0032289]; gastrulation with mouth forming second [GO:0001702]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; neuron development [GO:0048666]; positive regulation of gastrulation [GO:2000543]; positive regulation of myelination [GO:0031643]; positive regulation of oligodendrocyte differentiation [GO:0048714]; regulation of myelination [GO:0031641]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886] cell adhesion molecule binding [GO:0050839]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803] 0.96895 -6.6276 AYNRAGSWSVR 0 9.50526 0 0 0 0 10.2207 0 0 0 12.883 11.005 0 0 0 0 9.78046 11.2263 0 0 0 0 0 9.74265 0 0 8.4402 Q6N043 Z280D_HUMAN Zinc finger protein 280D (Suppressor of hairy wing homolog 4) (Zinc finger protein 634) ZNF280D KIAA1584 SUHW4 ZNF634 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.95991 -1.7266 FSSKNIKDLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1833 0 0 0 0 0 0 Q6N069 NAA16_HUMAN "N-alpha-acetyltransferase 16, NatA auxiliary subunit (NMDA receptor-regulated 1-like protein) (NARG1-like protein)" NAA16 NARG1L NAT2 Homo sapiens (Human) N-terminal peptidyl-methionine acetylation [GO:0017196]; N-terminal protein amino acid acetylation [GO:0006474]; negative regulation of apoptotic process [GO:0043066]; positive regulation of DNA-templated transcription [GO:0045893]; protein stabilization [GO:0050821] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; NatA complex [GO:0031415]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] ribosome binding [GO:0043022] 0.47865 0.62505 LLVEEIKGEILLKLGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.526 0 0 0 0 0 0 0 0 0 0 0 Q6NSI1 AR26L_HUMAN Putative ankyrin repeat domain-containing protein 26-like protein ANKRD26P1 Homo sapiens (Human) 0.88015 0.012957 ATEPANGK 0 0 0 0 0 0 0 0 0 9.30574 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.25091 8.14832 Q6NSI3 FA53A_HUMAN Protein FAM53A (Dorsal neural-tube nuclear protein) FAM53A Homo sapiens (Human) protein import into nucleus [GO:0006606] nucleus [GO:0005634] 0.95909 -1.7625 RSSGDPR 0 0 0 0 0 10.1034 0 0 0 0 0 0 0 0 0 9.6717 0 0 10.1387 0 0 0 0 0 0 0 0 Q6NSI4 RADX_HUMAN "RPA-related protein RADX (RPA-related and RAD51-antagonist, X-chromosome)" RADX CXorf57 Homo sapiens (Human) negative regulation of double-strand break repair via homologous recombination [GO:2000042]; regulation of DNA repair [GO:0006282] nuclear speck [GO:0016607]; replication fork [GO:0005657] RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697] 0.96775 -2.7926 EIEDLQYR 0 0 0 0 11.0156 0 0 9.51653 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6NSI8 SANBR_HUMAN SANT and BTB domain regulator of class switch recombination (SANT and BTB domain regulator of CSR) SANBR KIAA1841 Homo sapiens (Human) isotype switching [GO:0045190] identical protein binding [GO:0042802] 0.96924 -4.5011 EKALEKSASR 0 0 0 0 0 0 0 0 0 0 0 10.6523 0 0 0 0 0 9.3291 0 10.1101 0 0 0 0 0 0 0 Q6NSJ0 MYORG_HUMAN Myogenesis-regulating glycosidase (EC 3.2.1.-) (Uncharacterized family 31 glucosidase KIAA1161) MYORG KIAA1161 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of protein kinase B signaling [GO:0051897]; skeletal muscle fiber development [GO:0048741] endoplasmic reticulum membrane [GO:0005789]; nuclear membrane [GO:0031965] "hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]" 0.46185 0.63685 DPIWSTWALYGRAVDQDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.88762 0 0 0 0 0 0 10.2808 Q6NSJ2 PHLB3_HUMAN Pleckstrin homology-like domain family B member 3 PHLDB3 Homo sapiens (Human) enzyme binding [GO:0019899] 0.96391 -2.216 EQEQRRLSQER 0 0 0 0 0 0 0 0 0 8.99591 0 0 0 0 0 0 0 0 0 9.86405 0 11.2137 0 0 0 0 0 Q6NSJ5 LRC8E_HUMAN Volume-regulated anion channel subunit LRRC8E (Leucine-rich repeat-containing protein 8E) LRRC8E Homo sapiens (Human) aspartate transmembrane transport [GO:0015810]; cell volume homeostasis [GO:0006884]; cellular response to osmotic stress [GO:0071470]; cyclic-GMP-AMP transmembrane import across plasma membrane [GO:0140361]; monoatomic anion transmembrane transport [GO:0098656] cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; lysosomal membrane [GO:0005765]; monoatomic ion channel complex [GO:0034702]; plasma membrane [GO:0005886] volume-sensitive anion channel activity [GO:0005225] 0.57266 0.47977 ALSEVSGENQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.476 0 0 9.43767 0 0 9.8275 0 0 Q6NSX1 CCD70_HUMAN Coiled-coil domain-containing protein 70 CCDC70 Homo sapiens (Human) mitochondrion [GO:0005739]; plasma membrane [GO:0005886] 0.96917 -3.3747 AFWKEDNALWER 0 0 0 0 0 0 0 10.5502 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.41756 0 0 0 0 Q6NSZ9 ZSC25_HUMAN Zinc finger and SCAN domain-containing protein 25 (Zinc finger protein 498) ZSCAN25 ZNF498 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.91447 -0.82663 ELQELCRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.42524 0 0 0 Q6NT04 TIGD7_HUMAN Tigger transposable element-derived protein 7 TIGD7 Homo sapiens (Human) nucleus [GO:0005634] DNA binding [GO:0003677] 0.96454 -2.6995 QKLSMIIK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.38582 0 0 0 0 0 0 0 0 8.6405 0 10.9866 0 0 Q6NT32 EST5A_HUMAN Carboxylesterase 5A (EC 3.1.1.1) (Carboxylesterase-like urinary excreted protein homolog) (Cauxin) CES5A CES7 Homo sapiens (Human) extracellular region [GO:0005576] carboxylesterase activity [GO:0106435] 0.71074 0.36799 LGIFGFFTTWDQHAPGNWAFK 0 0 0 0 0 10.9576 0 0 0 0 0 0 0 0 0 0 10.9335 0 0 0 0 0 0 0 0 0 0 Q6NT55 CP4FN_HUMAN Ultra-long-chain fatty acid omega-hydroxylase (EC 1.14.14.177) (Cytochrome P450 4F22) CYP4F22 Homo sapiens (Human) ceramide biosynthetic process [GO:0046513]; icosanoid metabolic process [GO:0006690] endoplasmic reticulum membrane [GO:0005789] "heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]" 0.84169 0.14971 CVFSYNSNCQEK 0 0 0 0 0 0 0 0 0 10.9817 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6NT76 HMBX1_HUMAN Homeobox-containing protein 1 (Homeobox telomere-binding protein 1) (Telomere-associated homeobox-containing protein 1) HMBOX1 HOT1 TAH1 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of chromatin binding [GO:0035563]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of telomerase activity [GO:0051972] "Cajal body [GO:0015030]; centrosome [GO:0005813]; chromatin [GO:0000785]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]" double-stranded telomeric DNA binding [GO:0003691]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; telomeric DNA binding [GO:0042162] 0.84199 0.17802 QTPPPVSATSGTFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.51341 0 0 0 0 Q6NT89 TRNP1_HUMAN TMF-regulated nuclear protein 1 TRNP1 C1orf225 TRNP Homo sapiens (Human) cell cycle [GO:0007049]; cerebellar cortex morphogenesis [GO:0021696]; neural precursor cell proliferation [GO:0061351]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127] euchromatin [GO:0000791]; nucleus [GO:0005634] DNA binding [GO:0003677] 0.88869 -0.40479 ALELAEARR 0 0 0 0 0 0 9.97083 0 0 0 0 0 0 8.65585 0 0 11.524 0 0 0 0 0 0 0 0 0 0 Q6NTE8 MRNIP_HUMAN MRN complex-interacting protein (MRN-interacting protein) MRNIP C5orf45 Homo sapiens (Human) DNA damage response [GO:0006974]; DNA repair [GO:0006281]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of protein kinase activity [GO:0045860]; protein localization to chromatin [GO:0071168]; regulation of double-strand break repair via nonhomologous end joining [GO:2001032]; response to ionizing radiation [GO:0010212] nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682] 0.96542 -2.7204 QPSSKMEEPGPRFSQDLPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.70267 0 Q6NTF7 ABC3H_HUMAN DNA dC->dU-editing enzyme APOBEC-3H (EC 3.5.4.38) (APOBEC-related protein 10) (ARP-10) (Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3H) (A3H) APOBEC3H Homo sapiens (Human) cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral process [GO:0048525]; retrotransposon silencing [GO:0010526] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932] cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270] 0.9151 -0.79024 AQGRYMDILCDAEV 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3194 0 0 Q6NUI2 GPAT2_HUMAN "Glycerol-3-phosphate acyltransferase 2, mitochondrial (GPAT-2) (EC 2.3.1.15) (1-acylglycerol-3-phosphate O-acyltransferase GPAT2) (EC 2.3.1.51) (xGPAT1)" GPAT2 Homo sapiens (Human) CDP-diacylglycerol biosynthetic process [GO:0016024]; fatty acid metabolic process [GO:0006631]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphatidic acid biosynthetic process [GO:0006654]; piRNA processing [GO:0034587]; triglyceride biosynthetic process [GO:0019432] mitochondrial membrane [GO:0031966]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739] 1-acylglycerol-3-phosphate O-acyltransferase activity [GO:0003841]; glycerol-3-phosphate O-acyltransferase activity [GO:0004366]; sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity [GO:0102420] 0.44742 0.6453 ACSPALR 0 0 0 0 0 0 0 0 0 11.6487 0 0 10.6609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6NUI6 CHADL_HUMAN Chondroadherin-like protein CHADL SLRR4B Homo sapiens (Human) negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of collagen fibril organization [GO:1904027] cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615] collagen binding [GO:0005518]; collagen fibril binding [GO:0098633]; extracellular matrix structural constituent conferring compression resistance [GO:0030021] 0.84822 0.15563 AAAAVFEDCPGWAAR 11.8623 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.75345 0 0 0 0 0 0 0 0 0 0 0 Q6NUJ1 SAPL1_HUMAN Proactivator polypeptide-like 1 [Cleaved into: Saposin A-like; Saposin B-Val-like; Saposin B-like; Saposin C-like; Saposin D-like] PSAPL1 Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; epithelial cell differentiation involved in prostate gland development [GO:0060742]; prostate gland growth [GO:0060736]; regulation of lipid metabolic process [GO:0019216]; sphingolipid metabolic process [GO:0006665] cytosol [GO:0005829]; extracellular region [GO:0005576]; lysosome [GO:0005764] 0.95498 -1.5676 FIRLCGNR 0 0 0 0 0 0 0 0 0 0 0 9.52859 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6NUJ5 PWP2B_HUMAN PWWP domain-containing protein 2B PWWP2B PWWP2 Homo sapiens (Human) chromatin remodeling [GO:0006338]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; regulation of cold-induced thermogenesis [GO:0120161] nucleoplasm [GO:0005654]; nucleus [GO:0005634] NuRD complex binding [GO:0120325] 0.76105 0.29611 LSPFSEFFK 0 9.15964 0 0 0 0 0 0 0 0 0 0 0 0 8.7924 0 0 0 0 8.7659 0 0 0 0 0 0 0 Q6NUK1 SCMC1_HUMAN Mitochondrial adenyl nucleotide antiporter SLC25A24 (Mitochondrial ATP-Mg/Pi carrier protein 1) (Mitochondrial Ca(2+)-dependent solute carrier protein 1) (Short calcium-binding mitochondrial carrier protein 1) (SCaMC-1) (Solute carrier family 25 member 24) SLC25A24 APC1 MCSC1 SCAMC1 Homo sapiens (Human) adenine nucleotide transport [GO:0051503]; ADP transport [GO:0015866]; ATP transport [GO:0015867]; cellular response to calcium ion [GO:0071277]; cellular response to oxidative stress [GO:0034599]; mitochondrial ATP transmembrane transport [GO:1990544]; mitochondrial transport [GO:0006839] membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] adenine nucleotide transmembrane transporter activity [GO:0000295]; ADP:inorganic phosphate antiporter activity [GO:0140988]; ATP transmembrane transporter activity [GO:0005347]; ATP:inorganic phosphate antiporter activity [GO:0140987]; calcium ion binding [GO:0005509]; ion binding [GO:0043167] 0.92712 -1.2041 DGKLDFEEFMK 11.544 0 0 0 9.14389 0 0 0 0 0 0 9.38836 0 0 0 0 0 0 0 0 11.0144 0 0 0 0 0 0 Q6NUK4 REEP3_HUMAN Receptor expression-enhancing protein 3 REEP3 C10orf74 Homo sapiens (Human) cell division [GO:0051301]; endoplasmic reticulum tubular network organization [GO:0071786]; mitotic nuclear membrane reassembly [GO:0007084]; nuclear envelope organization [GO:0006998] cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum tubular network [GO:0071782] microtubule binding [GO:0008017] 0.95439 -1.5348 EVRYGSLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.87593 0 0 0 0 0 0 Q6NUN0 ACSM5_HUMAN "Acyl-coenzyme A synthetase ACSM5, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 5)" ACSM5 MACS3 Homo sapiens (Human) acyl-CoA metabolic process [GO:0006637]; fatty acid biosynthetic process [GO:0006633] mitochondrial matrix [GO:0005759] ATP binding [GO:0005524]; butyrate-CoA ligase activity [GO:0047760]; fatty acid ligase activity [GO:0015645]; fatty-acyl-CoA synthase activity [GO:0004321]; GTP binding [GO:0005525]; medium-chain fatty acid-CoA ligase activity [GO:0031956]; metal ion binding [GO:0046872] 0.92429 -0.9487 TVSGKIQR 0 0 0 0 0 9.10991 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6NUN7 JHY_HUMAN Jhy protein homolog JHY C11orf63 Homo sapiens (Human) axoneme assembly [GO:0035082]; brain development [GO:0007420]; cell differentiation [GO:0030154]; cerebrospinal fluid circulation [GO:0090660]; establishment of localization in cell [GO:0051649]; motile cilium assembly [GO:0044458]; regulation of establishment of planar polarity [GO:0090175] extracellular region [GO:0005576] 0.96842 -3.6476 KQCKHQNGLK 0 0 0 0 0 0 0 9.49929 0 0 0 0 0 0 9.80972 0 0 0 0 0 0 0 0 0 0 0 0 Q6NUN9 ZN746_HUMAN Zinc finger protein 746 (Parkin-interacting substrate) (PARIS) ZNF746 PARIS Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; transcription cis-regulatory region binding [GO:0000976]; ubiquitin protein ligase binding [GO:0031625]" 0.92614 -0.96449 ELYKHVMR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.28873 0 0 0 0 0 Q6NUP7 PP4R4_HUMAN Serine/threonine-protein phosphatase 4 regulatory subunit 4 PPP4R4 KIAA1622 PP4R4 Homo sapiens (Human) blastocyst hatching [GO:0001835]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; regulation of protein serine/threonine phosphatase activity [GO:0080163] cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein serine/threonine phosphatase complex [GO:0008287] protein phosphatase regulator activity [GO:0019888] 0.96935 -4.5601 DEGSSVR 10.6648 0 0 0 0 0 0 0 0 0 8.74705 0 0 0 0 0 0 0 10.127 0 0 0 0 0 0 0 0 Q6NUQ1 RINT1_HUMAN RAD50-interacting protein 1 (RAD50 interactor 1) (HsRINT-1) (RINT-1) RINT1 Homo sapiens (Human) "endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; protein transport [GO:0015031]; regulation of ER to Golgi vesicle-mediated transport [GO:0060628]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]" cytosol [GO:0005829]; Dsl1/NZR complex [GO:0070939]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789] 0.96957 -4.0447 GLMMLVLEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.18237 0 0 0 0 0 Q6NUQ4 TM214_HUMAN Transmembrane protein 214 TMEM214 PP446 Homo sapiens (Human) apoptotic process [GO:0006915] cytoplasmic microtubule [GO:0005881]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794] 0.82932 0.20505 ALGEANGVWK 0 0 0 0 0 0 0 0 8.65885 0 0 0 9.84594 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6NUT2 D19L2_HUMAN Probable C-mannosyltransferase DPY19L2 (EC 2.4.1.-) (Dpy-19-like protein 2) (Protein dpy-19 homolog 2) DPY19L2 UNQ3127/PRO10284 Homo sapiens (Human) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan [GO:0018406]; spermatid development [GO:0007286] nuclear inner membrane [GO:0005637]; nucleus [GO:0005634] mannosyltransferase activity [GO:0000030] 0.32166 0.78601 LQSSGRSQSKGR 0 11.0978 0 0 0 0 12.7698 0 13.2025 0 0 0 0 0 0 12.6543 0 0 0 0 0 9.26059 0 0 0 0 0 Q6NV74 CRCDL_HUMAN CRACD-like protein CRACDL C2orf55 KIAA1211L Homo sapiens (Human) 0.9601 -1.8497 EAETEPER 0 0 0 0 8.97565 0 11.2256 0 0 0 0 0 0 0 0 0 0 9.54363 0 0 0 0 0 0 0 0 0 Q6NVH7 SWAP1_HUMAN ATPase SWSAP1 (SWIM-type zinc finger 7-associated protein 1) (SWS1-associated protein 1) (ZSWIM7-associated protein 1) (ZSWIM7AP1) SWSAP1 C19orf39 Homo sapiens (Human) double-strand break repair via homologous recombination [GO:0000724]; protein stabilization [GO:0050821] nucleus [GO:0005634]; Shu complex [GO:0097196] ATP hydrolysis activity [GO:0016887]; single-stranded DNA binding [GO:0003697] 0.95064 -1.3838 TEWWVTFR 0 0 0 0 0 0 0 0 0 9.52186 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6NVV7 CDPF1_HUMAN Cysteine-rich DPF motif domain-containing protein 1 CDPF1 C22orf40 Homo sapiens (Human) 0.89872 -0.56805 TPSQPGSR 0 0 0 0 0 0 0 0 0 0 0 0 0 8.35878 0 0 0 0 0 0 0 0 0 0 0 0 8.2133 Q6NVV9 ADAM5_HUMAN "Putative disintegrin and metalloproteinase domain-containing protein 5 (Putative transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein II) (tMDC II)" ADAM5 ADAM5P TMDC2 Homo sapiens (Human) 0.89818 -0.55807 DQTCVSTYLPRR 0 0 0 0 0 9.28091 0 0 10.9234 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6NVY1 HIBCH_HUMAN "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (EC 3.1.2.4) (3-hydroxyisobutyryl-coenzyme A hydrolase) (HIB-CoA hydrolase) (HIBYL-CoA-H)" HIBCH Homo sapiens (Human) branched-chain amino acid catabolic process [GO:0009083]; valine catabolic process [GO:0006574] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] 3-hydroxyisobutyryl-CoA hydrolase activity [GO:0003860] 0.96691 -2.3203 LMSRFNAFKR 0 0 0 0 10.215 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6NW29 RWDD4_HUMAN RWD domain-containing protein 4 (Protein FAM28A) RWDD4 FAM28A RWDD4A Homo sapiens (Human) 0.88241 -0.094518 GWNWVDVVK 17.2872 17.2179 16.9887 15.9658 16.2673 16.0586 16.8824 17.1783 17.0588 16.3687 16.5905 16.8382 15.85 16.0788 16.1809 16.9372 17.2544 16.7133 12.9711 12.524 12.537 0 12.3307 12.402 13.233 0 0 Q6NW34 NEPRO_HUMAN Nucleolus and neural progenitor protein NEPRO C3orf17 Homo sapiens (Human) negative regulation of neuron differentiation [GO:0045665]; positive regulation of Notch signaling pathway [GO:0045747] nucleolus [GO:0005730]; nucleus [GO:0005634] 0.94837 -1.3645 LSHCTVHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.73129 0 0 0 0 0 0 0 0 0 0 0 Q6NWY9 PR40B_HUMAN Pre-mRNA-processing factor 40 homolog B (Huntingtin yeast partner C) (Huntingtin-interacting protein C) PRPF40B HYPC Homo sapiens (Human) "mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]" nuclear speck [GO:0016607]; U1 snRNP [GO:0005685]; U2-type prespliceosome [GO:0071004] RNA binding [GO:0003723] 0.96285 -2.1277 AQREKEEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.05 0 0 0 0 0 0 0 0 0 0 0 Q6NXG1 ESRP1_HUMAN Epithelial splicing regulatory protein 1 (RNA-binding motif protein 35A) (RNA-binding protein 35A) ESRP1 RBM35A Homo sapiens (Human) mRNA processing [GO:0006397]; regulation of inner ear auditory receptor cell fate specification [GO:0042669]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] mRNA binding [GO:0003729] 0.95993 -1.9696 GGAALCLNAQGRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.57493 0 0 0 0 0 0 0 0 0 Q6NXT1 ANR54_HUMAN Ankyrin repeat domain-containing protein 54 (Lyn-interacting ankyrin repeat protein) ANKRD54 LIAR Homo sapiens (Human) nucleocytoplasmic transport [GO:0006913]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of intracellular signal transduction [GO:1902531]; regulation of protein kinase activity [GO:0045859] cytoplasm [GO:0005737]; midbody [GO:0030496]; nucleus [GO:0005634] protein kinase regulator activity [GO:0019887]; protein-containing complex binding [GO:0044877] 0.94818 -1.3655 EYLERLGQHEQRER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0428 0 0 Q6NXT6 TAPT1_HUMAN Transmembrane anterior posterior transformation protein 1 homolog (Cytomegalovirus partial fusion receptor) TAPT1 CMVFR Homo sapiens (Human) cartilage development [GO:0051216]; cell projection organization [GO:0030030]; embryonic skeletal system development [GO:0048706]; neural crest cell development [GO:0014032]; ossification [GO:0001503]; positive regulation of bone development [GO:1903012]; positive regulation of cartilage development [GO:0061036]; positive regulation of cilium assembly [GO:0045724] centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654] growth hormone-releasing hormone receptor activity [GO:0016520] 0.91428 -0.81989 KDLLEIDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2379 0 0 0 0 0 0 0 0 0 0 Q6NY19 KANK3_HUMAN KN motif and ankyrin repeat domain-containing protein 3 (Ankyrin repeat domain-containing protein 47) KANK3 ANKRD47 Homo sapiens (Human) negative regulation of actin filament polymerization [GO:0030837] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856] 0.92176 -1.1227 LATSERGGRAR 0 0 0 9.01229 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3421 0 0 0 0 0 0 Q6NYC1 JMJD6_HUMAN Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (EC 1.14.11.-) (Histone arginine demethylase JMJD6) (JmjC domain-containing protein 6) (Jumonji domain-containing protein 6) (Lysyl-hydroxylase JMJD6) (Peptide-lysine 5-dioxygenase JMJD6) (Phosphatidylserine receptor) (Protein PTDSR) JMJD6 KIAA0585 PSR PTDSR Homo sapiens (Human) "cell surface receptor signaling pathway [GO:0007166]; erythrocyte development [GO:0048821]; heart development [GO:0007507]; histone H3-R2 demethylation [GO:0070078]; histone H4-R3 demethylation [GO:0070079]; kidney development [GO:0001822]; lung development [GO:0030324]; macrophage activation [GO:0042116]; mRNA processing [GO:0006397]; oxidative RNA demethylation [GO:0035513]; peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine [GO:0018395]; phagocytosis [GO:0006909]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein homooligomerization [GO:0051260]; recognition of apoptotic cell [GO:0043654]; regulation of mRNA splicing, via spliceosome [GO:0048024]; retina development in camera-type eye [GO:0060041]; RNA splicing [GO:0008380]; sprouting angiogenesis [GO:0002040]; T cell differentiation in thymus [GO:0033077]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904] histone demethylase activity [GO:0032452]; histone H3R2 demethylase activity [GO:0033746]; histone H3R3 demethylase activity [GO:0033749]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidative RNA demethylase activity [GO:0035515]; P-TEFb complex binding [GO:0106140]; peptidyl-lysine 5-dioxygenase activity [GO:0070815]; protein demethylase activity [GO:0140457]; RNA binding [GO:0003723]; signaling receptor activity [GO:0038023]; single-stranded RNA binding [GO:0003727]; transcription regulator activator activity [GO:0140537] 0.95552 -1.5405 CGEDNDGYSVKMK 0 0 0 0 0 9.98897 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6NYC8 PPR18_HUMAN Phostensin (Protein phosphatase 1 F-actin cytoskeleton-targeting subunit) (Protein phosphatase 1 regulatory subunit 18) PPP1R18 HKMT1098 KIAA1949 Homo sapiens (Human) cytoplasm [GO:0005737]; cytoskeleton [GO:0005856] actin binding [GO:0003779]; phosphatase binding [GO:0019902] 0.96329 -2.6553 ALIVDESCRR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9756 0 0 0 10.6009 0 0 0 0 0 9.14277 0 0 0 Q6NZI2 CAVN1_HUMAN Caveolae-associated protein 1 (Cavin-1) (Polymerase I and transcript release factor) CAVIN1 PTRF FKSG13 Homo sapiens (Human) positive regulation of cell motility [GO:2000147]; protein secretion [GO:0009306]; rRNA transcription [GO:0009303]; termination of RNA polymerase I transcription [GO:0006363]; transcription initiation at RNA polymerase I promoter [GO:0006361] caveola [GO:0005901]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] identical protein binding [GO:0042802]; RNA binding [GO:0003723]; rRNA primary transcript binding [GO:0042134] 0.83536 0.18681 GEAGDLR 10.4592 0 0 0 0 0 0 0 0 0 0 0 0 10.0889 10.1957 0 0 0 0 0 0 0 0 0 0 0 0 Q6NZY4 ZCHC8_HUMAN Zinc finger CCHC domain-containing protein 8 (TRAMP-like complex RNA-binding factor ZCCHC8) ZCCHC8 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; ncRNA processing [GO:0034470]; snRNA catabolic process [GO:0016076]" catalytic step 2 spliceosome [GO:0071013]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; TRAMP complex [GO:0031499] RNA binding [GO:0003723]; zinc ion binding [GO:0008270] 0.69602 0.37749 LFPADTSPSTATK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2711 10.0887 0 0 9.98627 0 Q6NZY7 BORG3_HUMAN Cdc42 effector protein 5 (Binder of Rho GTPases 3) CDC42EP5 BORG3 CEP5 Homo sapiens (Human) JNK cascade [GO:0007254]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of pseudopodium assembly [GO:0031274]; regulation of cell shape [GO:0008360]; Rho protein signal transduction [GO:0007266] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; membrane [GO:0016020]; plasma membrane [GO:0005886] small GTPase binding [GO:0031267] 0.89807 -0.56805 APPAGAPR 0 0 9.84293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6P047 CH074_HUMAN Uncharacterized protein C8orf74 C8orf74 Homo sapiens (Human) 0.95106 -1.4148 DLWIHEQQVATLTEAEAQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.5065 0 0 0 0 0 0 0 0 0 11.2231 Q6P050 FXL22_HUMAN F-box and leucine-rich protein 22 FBXL22 Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567] cytosol [GO:0005829]; nucleolus [GO:0005730]; Z disc [GO:0030018] ubiquitin protein ligase activity [GO:0061630] 0.96183 -2.6108 HESLVNDFLLR 0 0 0 0 0 0 10.033 8.85431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6P0N0 M18BP_HUMAN Mis18-binding protein 1 (Kinetochore-associated protein KNL-2 homolog) (HsKNL-2) (P243) MIS18BP1 C14orf106 KIAA1903 KNL2 M18BP1 Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301] "chromosome, centromeric region [GO:0000775]; nucleoplasm [GO:0005654]" DNA binding [GO:0003677] 0.96878 -7.6956 AVTDFVIPECQK 0 13.233 12.836 0 0 11.2684 11.3745 0 0 9.78393 0 0 0 0 0 0 0 0 11.7365 0 0 0 0 0 0 0 0 Q6P0Q8 MAST2_HUMAN Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1) MAST2 KIAA0807 MAST205 Homo sapiens (Human) cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]; regulation of interleukin-12 production [GO:0032655]; spermatid differentiation [GO:0048515] cytoplasm [GO:0005737]; microtubule cytoskeleton [GO:0015630]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; phosphatase binding [GO:0019902]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96251 -2.5072 ALGTLRQDR 0 0 0 9.53125 0 0 0 0 0 0 0 0 0 0 8.84251 0 0 0 0 0 12.0794 11.0615 0 0 10.2554 0 0 Q6P158 DHX57_HUMAN Putative ATP-dependent RNA helicase DHX57 (EC 3.6.4.13) (DEAH box protein 57) DHX57 Homo sapiens (Human) ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; helicase activity [GO:0004386]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.92412 -1.0543 INNPACHK 0 0 0 0 0 0 0 0 0 0 0 0 9.98428 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4157 Q6P161 RM54_HUMAN "Large ribosomal subunit protein mL54 (39S ribosomal protein L54, mitochondrial) (L54mt) (MRP-L54)" MRPL54 Homo sapiens (Human) mitochondrial translation [GO:0032543] mitochondrial inner membrane [GO:0005743]; mitochondrial large ribosomal subunit [GO:0005762]; mitochondrion [GO:0005739] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.94494 -1.34 DPDVCTDPVQLTTYAMGVNIYK 0 0 0 11.1365 11.2203 11.2161 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6P179 ERAP2_HUMAN Endoplasmic reticulum aminopeptidase 2 (EC 3.4.11.-) (Leukocyte-derived arginine aminopeptidase) (L-RAP) ERAP2 LRAP Homo sapiens (Human) adaptive immune response [GO:0002250]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217] cytoplasm [GO:0005737]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789] aminopeptidase activity [GO:0004177]; endopeptidase activity [GO:0004175]; metalloaminopeptidase activity [GO:0070006]; metallopeptidase activity [GO:0008237]; peptide binding [GO:0042277]; zinc ion binding [GO:0008270] 0.96964 -3.4363 ELKVLSYPAHEQIALLVPEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.153 11.3082 0 0 0 0 0 0 Q6P1A2 MBOA5_HUMAN Lysophospholipid acyltransferase 5 (LPLAT 5) (EC 2.3.1.-) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.n7) (1-acylglycerophosphoserine O-acyltransferase) (EC 2.3.1.n6) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lyso-PC acyltransferase) (Lysophosphatidylcholine acyltransferase 3) (Lyso-PC acyltransferase 3) (Lysophosphatidylserine acyltransferase) (LPSAT) (Lyso-PS acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 5) (O-acyltransferase domain-containing protein 5) LPCAT3 MBOAT5 OACT5 Homo sapiens (Human) chylomicron assembly [GO:0034378]; endoplasmic reticulum membrane organization [GO:0090158]; intestinal stem cell homeostasis [GO:0036335]; lipid modification [GO:0030258]; negative regulation of inflammatory response [GO:0050728]; negative regulation of response to endoplasmic reticulum stress [GO:1903573]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylcholine biosynthetic process [GO:0006656]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylserine acyl-chain remodeling [GO:0036150]; positive regulation of intestinal cholesterol absorption [GO:0045797]; positive regulation of triglyceride transport [GO:1905885]; regulation of cholesterol biosynthetic process [GO:0045540]; very-low-density lipoprotein particle assembly [GO:0034379] endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] 1-acylglycerol-3-phosphate O-acyltransferase activity [GO:0003841]; 1-acylglycerophosphocholine O-acyltransferase activity [GO:0047184]; 1-acylglycerophosphoethanolamine O-acyltransferase activity [GO:0106262]; 1-acylglycerophosphoserine O-acyltransferase activity [GO:0106263]; 2-acylglycerol-3-phosphate O-acyltransferase activity [GO:0047144]; lysophospholipid acyltransferase activity [GO:0071617] 0.89788 -0.67961 AKWDACANMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.29609 0 0 0 0 0 0 0 0 0 0 0 Q6P1J6 PLB1_HUMAN "Phospholipase B1, membrane-associated (Phospholipase B) (hPLB) (Lysophospholipase) (EC 3.1.1.5) (Phospholipase A2) (EC 3.1.1.4) (Phospholipase B/lipase) (PLB/LIP) (Triacylglycerol lipase) (EC 3.1.1.3)" PLB1 PLB Homo sapiens (Human) diacylglycerol catabolic process [GO:0046340]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylcholine catabolic process [GO:0034638]; phosphatidylethanolamine catabolic process [GO:0046338]; phosphatidylglycerol catabolic process [GO:0034478]; phospholipid metabolic process [GO:0006644]; positive regulation of acrosome reaction [GO:2000344]; retinoid metabolic process [GO:0001523]; triglyceride catabolic process [GO:0019433] apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; plasma membrane [GO:0005886] calcium-independent phospholipase A2 activity [GO:0047499]; lysophospholipase activity [GO:0004622]; phosphatidyl phospholipase B activity [GO:0102545]; phospholipase A2 activity [GO:0004623]; retinyl-palmitate esterase activity [GO:0050253]; triglyceride lipase activity [GO:0004806] 0.9235 -1.0176 IHFQEDWK 0 0 0 0 0 0 0 0 0 0 0 11.66 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6P1L5 F117B_HUMAN Protein FAM117B (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 13 protein) FAM117B ALS2CR13 Homo sapiens (Human) 0.96803 -3.6602 LRQQLQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1925 0 0 Q6P1M0 S27A4_HUMAN Long-chain fatty acid transport protein 4 (FATP-4) (Fatty acid transport protein 4) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 4) (Very long-chain acyl-CoA synthetase 4) (ACSVL4) (EC 6.2.1.-) SLC27A4 ACSVL4 FATP4 Homo sapiens (Human) "activation of GTPase activity [GO:0090630]; establishment of localization in cell [GO:0051649]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; glucose import in response to insulin stimulus [GO:0044381]; lipid transport across blood-brain barrier [GO:1990379]; long-chain fatty acid import into cell [GO:0044539]; long-chain fatty acid metabolic process [GO:0001676]; long-chain fatty acid transport [GO:0015909]; medium-chain fatty acid transport [GO:0001579]; negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity [GO:0062003]; negative regulation of insulin receptor signaling pathway [GO:0046627]; positive regulation of apoptotic process [GO:0043065]; response to nutrient [GO:0007584]; skin development [GO:0043588]; transport across blood-brain barrier [GO:0150104]; very long-chain fatty acid catabolic process [GO:0042760]" brush border membrane [GO:0031526]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; microvillus [GO:0005902]; plasma membrane [GO:0005886] arachidonate-CoA ligase activity [GO:0047676]; fatty acid transmembrane transporter activity [GO:0015245]; long-chain fatty acid transporter activity [GO:0005324]; long-chain fatty acid-CoA ligase activity [GO:0004467]; nucleotide binding [GO:0000166]; oleate transmembrane transporter activity [GO:1901480]; oleoyl-CoA ligase activity [GO:0090434]; palmitoyl-CoA ligase activity [GO:0090433]; very long-chain fatty acid-CoA ligase activity [GO:0031957] 0.96335 -2.1142 DPLRRFDGYLNQGANNK 0 0 0 0 10.7622 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6P1M9 ARMX5_HUMAN Armadillo repeat-containing X-linked protein 5 ARMCX5 Homo sapiens (Human) 0.96896 -3.9013 MVDSGTEAR 0 11.357 0 11.6055 0 0 0 0 0 9.21476 9.85435 0 0 0 0 11.3943 0 0 0 0 0 0 0 0 0 0 0 Q6P1N0 C2D1A_HUMAN Coiled-coil and C2 domain-containing protein 1A (Akt kinase-interacting protein 1) (Five prime repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1) (Putative NF-kappa-B-activating protein 023N) CC2D1A AKI1 Homo sapiens (Human) negative regulation of snRNA transcription by RNA polymerase II [GO:1905381]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of transcription by RNA polymerase II [GO:0006357] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; plasma membrane [GO:0005886] "cadherin binding [GO:0045296]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.87737 -0.0032952 QAKGLEPMLEASR 0 0 0 0 0 0 0 0 0 0 0 10.1638 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6P1N9 TATD1_HUMAN Deoxyribonuclease TATDN1 (EC 3.1.21.-) (Hepatocarcinoma high expression protein) TATDN1 CDA11 Homo sapiens (Human) nucleoplasm [GO:0005654] 3'-5'-DNA exonuclease activity [GO:0008296]; metal ion binding [GO:0046872] 0.67766 0.39371 STHAGSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.1234 0 0 0 0 0 Q6P1Q0 LTMD1_HUMAN LETM1 domain-containing protein 1 (Cervical cancer 1 proto-oncogene protein p40) (Cervical cancer proto-oncogene 2 protein) (HCCR-1) (HCRR-2) LETMD1 Homo sapiens (Human) intracellular monoatomic cation homeostasis [GO:0030003]; mitochondrion organization [GO:0007005]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of inflammatory response [GO:0050727]; regulation of phagocytosis [GO:0050764] mitochondrial inner membrane [GO:0005743]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATPase activator activity [GO:0001671]; enzyme activator activity [GO:0008047]; molecular adaptor activity [GO:0060090]; ribosome binding [GO:0043022] 0.93292 -1.2655 IKTNMWKHNIK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.70077 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6P1S2 CC033_HUMAN Protein C3orf33 (Protein AC3-33) C3orf33 MSTP052 Homo sapiens (Human) negative regulation of ERK1 and ERK2 cascade [GO:0070373]; regulation of DNA-binding transcription factor activity [GO:0051090] extracellular space [GO:0005615]; membrane [GO:0016020] 0.96995 -4.3816 AELTALK 0 13.3712 0 0 11.4646 11.3373 12.7918 0 12.8259 12.3949 0 12.6813 0 9.53411 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6P1W5 CA094_HUMAN Uncharacterized protein C1orf94 C1orf94 Homo sapiens (Human) 0.92509 -0.97524 QKVAMPVISSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.58665 0 Q6P1X5 TAF2_HUMAN Transcription initiation factor TFIID subunit 2 (150 kDa cofactor of initiator function) (RNA polymerase II TBP-associated factor subunit B) (TBP-associated factor 150 kDa) (Transcription initiation factor TFIID 150 kDa subunit) (TAF(II)150) (TAFII-150) (TAFII150) TAF2 CIF150 TAF2B Homo sapiens (Human) G2/M transition of mitotic cell cycle [GO:0000086]; histone H3 acetylation [GO:0043966]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of transcription by RNA polymerase II [GO:0006357]; response to organic cyclic compound [GO:0014070]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription initiation at RNA polymerase II promoter [GO:0006367] nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor TFIID complex [GO:0005669]; transcription factor TFTC complex [GO:0033276] chromatin binding [GO:0003682]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; transcription cis-regulatory region binding [GO:0000976] 0.9647 -2.6918 HKILNMLTKNPPFTK 11.627 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.266 0 0 0 0 0 0 9.86152 0 0 0 Q6P1X6 CH082_HUMAN UPF0598 protein C8orf82 C8orf82 Homo sapiens (Human) 0.90947 -0.74609 TREYFYYVDHQGQLFLDDSK 0 0 0 0 0 0 0 10.8846 10.6862 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6P280 ZN529_HUMAN Zinc finger protein 529 ZNF529 KIAA1615 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.96359 -2.1422 AFGVCRELAR 0 0 0 0 9.23077 0 0 0 0 0 0 0 10.3691 0 0 0 12.0972 0 0 0 10.1815 0 0 0 0 0 0 Q6P2C0 WDR93_HUMAN WD repeat-containing protein 93 WDR93 Homo sapiens (Human) electron transport chain [GO:0022900] mitochondrial respiratory chain complex I [GO:0005747] 0.93148 -1.2557 LEKNPEKEEEHWAR 9.53181 9.68219 9.30982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6P2D8 XRRA1_HUMAN X-ray radiation resistance-associated protein 1 XRRA1 Homo sapiens (Human) response to X-ray [GO:0010165] cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.97009 -4.1433 DQKKPPTAPREVK 0 9.45238 11.3158 10.4786 0 0 0 0 0 0 10.2748 0 0 0 0 0 0 0 0 0 0 0 9.8963 0 0 0 0 Q6P2E9 EDC4_HUMAN Enhancer of mRNA-decapping protein 4 (Autoantigen Ge-1) (Autoantigen RCD-8) (Human enhancer of decapping large subunit) (Hedls) EDC4 HEDLS Homo sapiens (Human) deadenylation-independent decapping of nuclear-transcribed mRNA [GO:0031087] cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932] 0.94018 -1.3174 IVKGEVSVALK 0 0 0 0 0 13.0842 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6P2H3 CEP85_HUMAN Centrosomal protein of 85 kDa (Cep85) (Coiled-coil domain-containing protein 21) CEP85 CCDC21 Homo sapiens (Human) chromosome segregation [GO:0007059]; negative regulation of protein kinase activity [GO:0006469]; regulation of mitotic centrosome separation [GO:0046602] centrosome [GO:0005813]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleolus [GO:0005730]; pericentriolar material [GO:0000242]; spindle pole [GO:0000922] 0.9406 -1.3312 CQKESEQNR 10.9674 10.793 11.128 0 0 0 10.3533 10.5647 10.3664 0 0 11.2089 0 0 0 0 0 9.64505 0 0 0 0 0 0 0 0 0 Q6P2P2 ANM9_HUMAN Protein arginine N-methyltransferase 9 (Protein arginine N-methyltransferase 10) (EC 2.1.1.320) PRMT9 PRMT10 Homo sapiens (Human) mRNA processing [GO:0006397]; peptidyl-arginine methylation [GO:0018216] cytoplasm [GO:0005737] protein-arginine N-methyltransferase activity [GO:0016274]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]; protein-arginine omega-N symmetric methyltransferase activity [GO:0035243] 0.8739 0.031653 LTAIPFWYHMYLDEEIR 0 0 0 0 0 0 0 0 8.79617 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6P2Q9 PRP8_HUMAN Pre-mRNA-processing-splicing factor 8 (220 kDa U5 snRNP-specific protein) (PRP8 homolog) (Splicing factor Prp8) (p220) PRPF8 PRPC8 Homo sapiens (Human) "cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal tri-snRNP complex assembly [GO:0000244]" catalytic step 2 spliceosome [GO:0071013]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type catalytic step 1 spliceosome [GO:0071006]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682] K63-linked polyubiquitin modification-dependent protein binding [GO:0070530]; pre-mRNA intronic binding [GO:0097157]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U2 snRNA binding [GO:0030620]; U5 snRNA binding [GO:0030623]; U6 snRNA binding [GO:0017070] 0.95931 -1.9598 ASGFEESMKWKK 0 0 10.7147 0 0 0 0 10.3623 0 0 0 11.8164 11.1541 0 0 0 0 0 10.6584 0 0 0 10.4466 0 0 0 0 Q6P2S7 TTC41_HUMAN Putative tetratricopeptide repeat protein 41 (TPR repeat protein 41) (Grp94-neighboring nucleotidase) TTC41P GNN Homo sapiens (Human) cytoplasm [GO:0005737] 0.13191 1.0629 CAPGKGK 0 0 0 0 0 0 10.7462 10.7791 10.8636 0 13.8896 0 9.38241 10.8919 9.59356 0 0 0 0 0 0 0 12.4671 0 0 0 10.0844 Q6P3R8 NEK5_HUMAN Serine/threonine-protein kinase Nek5 (EC 2.7.11.1) (Never in mitosis A-related kinase 5) (NimA-related protein kinase 5) NEK5 Homo sapiens (Human) protein phosphorylation [GO:0006468] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.95819 -1.6802 AGAPASR 0 0 0 9.56792 0 0 0 0 0 0 0 0 0 0 0 9.81429 0 0 0 11.1845 0 0 0 0 0 10.9389 0 Q6P3S6 FBX42_HUMAN F-box only protein 42 (Just one F-box and Kelch domain-containing protein) FBXO42 FBX42 JFK KIAA1332 Homo sapiens (Human) SCF ubiquitin ligase complex [GO:0019005] ubiquitin ligase-substrate adaptor activity [GO:1990756] 0.60132 0.44108 TVGGSMR 0 8.61974 0 0 0 0 0 8.25162 0 9.32688 0 0 0 0 0 0 0 0 0 0 0 10.3907 0 9.29524 0 0 0 Q6P3V2 Z585A_HUMAN Zinc finger protein 585A ZNF585A Homo sapiens (Human) nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.92062 -1.1169 AFVQKPEFIIHQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.72 0 0 0 0 9.47464 0 0 0 0 Q6P3W7 SCYL2_HUMAN SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa) SCYL2 CVAK104 KIAA1360 Homo sapiens (Human) brain development [GO:0007420]; endosome to lysosome transport [GO:0008333]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of receptor internalization [GO:0002092]; protein phosphorylation [GO:0006468]; pyramidal neuron development [GO:0021860]; receptor internalization involved in canonical Wnt signaling pathway [GO:2000286] clathrin-coated vesicle [GO:0030136]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794] ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; signaling receptor binding [GO:0005102] 0.96854 -2.7655 LGSSSLTNIPEEVR 0 0 10.2818 0 0 0 0 10.3576 10.6199 0 0 0 0 0 10.0188 9.93783 0 9.85786 0 0 0 0 9.49079 0 0 0 0 Q6P3X8 PGBD2_HUMAN PiggyBac transposable element-derived protein 2 PGBD2 Homo sapiens (Human) sequence-specific DNA binding [GO:0043565] 0.96944 -6.3595 AVVKPQRIWTK 0 0 0 0 0 0 0 0 0 0 10.615 0 0 0 0 0 0 0 9.22035 0 0 10.4229 0 0 0 0 0 Q6P461 ACSM6_HUMAN "Acyl-coenzyme A synthetase ACSM6, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 6)" ACSM6 C10orf129 Homo sapiens (Human) acyl-CoA metabolic process [GO:0006637]; fatty acid biosynthetic process [GO:0006633] mitochondrial matrix [GO:0005759] ATP binding [GO:0005524]; butyrate-CoA ligase activity [GO:0047760]; fatty acid ligase activity [GO:0015645]; fatty-acyl-CoA synthase activity [GO:0004321]; GTP binding [GO:0005525]; medium-chain fatty acid-CoA ligase activity [GO:0031956]; metal ion binding [GO:0046872] 0.88238 -0.061947 GHMLYLTGDR 0 0 0 0 0 0 0 0 0 0 0 0 9.1228 0 8.96976 0 0 0 0 0 0 9.31639 9.22212 9.20709 9.51402 0 0 Q6P4A7 SFXN4_HUMAN Sideroflexin-4 (Breast cancer resistance marker 1) SFXN4 BCRM1 Homo sapiens (Human) amino acid transport [GO:0006865]; mitochondrial transmembrane transport [GO:1990542] intracellular membrane-bounded organelle [GO:0043231]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] monoatomic ion transmembrane transporter activity [GO:0015075]; transmembrane transporter activity [GO:0022857] 0.84605 0.1745 GIAVMDK 0 0 0 0 0 0 8.88059 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6P4A8 PLBL1_HUMAN Phospholipase B-like 1 (EC 3.1.1.-) (LAMA-like protein 1) (Lamina ancestor homolog 1) (Phospholipase B domain-containing protein 1) [Cleaved into: Phospholipase B-like 1 chain A; Phospholipase B-like 1 chain B; Phospholipase B-like 1 chain C] PLBD1 Homo sapiens (Human) phospholipid catabolic process [GO:0009395] cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764] phospholipase activity [GO:0004620] 0.95306 -1.4797 VTDTASMKYIMR 11.6241 0 0 0 11.6303 11.3432 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6P4F1 FUT10_HUMAN "Alpha-(1,3)-fucosyltransferase 10 (EC 2.4.1.-) (Fucosyltransferase X) (Fuc-TX) (FucT-X) (Galactoside 3-L-fucosyltransferase 10) (Fucosyltransferase 10)" FUT10 Homo sapiens (Human) cerebral cortex radially oriented cell migration [GO:0021799]; fertilization [GO:0009566]; fucosylation [GO:0036065]; hemopoiesis [GO:0030097]; L-fucose catabolic process [GO:0042355]; N-glycan fucosylation [GO:0036071]; nervous system development [GO:0007399]; neuroblast migration [GO:0097402]; neuronal stem cell division [GO:0036445]; neuronal stem cell population maintenance [GO:0097150]; oligosaccharide biosynthetic process [GO:0009312]; protein folding [GO:0006457]; protein glycosylation [GO:0006486]; protein targeting [GO:0006605]; wound healing [GO:0042060] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; lysosome [GO:0005764]; nucleoplasm [GO:0005654] alpha-(1->3)-fucosyltransferase activity [GO:0046920]; fucosyltransferase activity [GO:0008417] 0.9693 -4.8279 GEISNQR 9.65313 0 0 0 0 0 0 0 0 0 0 0 0 8.56932 0 0 9.98854 0 0 0 0 0 0 0 0 0 0 Q6P4F7 RHGBA_HUMAN Rho GTPase-activating protein 11A (Rho-type GTPase-activating protein 11A) ARHGAP11A KIAA0013 Homo sapiens (Human) positive regulation of GTPase activity [GO:0043547]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] cytosol [GO:0005829]; nucleus [GO:0005634] GTPase activator activity [GO:0005096] 0.96887 -3.3438 AFYGIKVKGVR 0 0 0 0 0 0 0 0 0 9.77304 0 11.2044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6P4I2 WDR73_HUMAN WD repeat-containing protein 73 WDR73 HSPC264 Homo sapiens (Human) cytoplasmic microtubule organization [GO:0031122]; negative regulation of apoptotic process [GO:0043066]; nucleus organization [GO:0006997] cleavage furrow [GO:0032154]; cytosol [GO:0005829]; spindle pole [GO:0000922] 0.94396 -1.3353 GVFVAGYESLK 0 9.89271 0 0 0 0 0 0 0 9.57031 0 8.95507 0 0 0 0 0 9.48625 0 0 0 0 0 0 0 0 0 Q6P4Q7 CNNM4_HUMAN Metal transporter CNNM4 (Ancient conserved domain-containing protein 4) (Cyclin-M4) CNNM4 ACDP4 KIAA1592 Homo sapiens (Human) enamel mineralization [GO:0070166]; intracellular monoatomic cation homeostasis [GO:0030003]; magnesium ion homeostasis [GO:0010960]; magnesium ion transport [GO:0015693]; response to stimulus [GO:0050896]; visual perception [GO:0007601] basolateral plasma membrane [GO:0016323]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] magnesium ion transmembrane transporter activity [GO:0015095]; sodium ion transmembrane transporter activity [GO:0015081] 0.96051 -1.9872 GQGSPQQGTIVGMR 11.6241 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6P575 BGP11_HUMAN Putative inactive beta-glucuronidase protein GUSBP11 (Beta-glucuronidase pseudogene 11) GUSBP11 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975] "hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]" 0.88402 -0.31561 TAAETGRGKPR 0 0 0 0 0 0 0 0 0 9.27137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6P587 FAHD1_HUMAN "Acylpyruvase FAHD1, mitochondrial (EC 3.7.1.5) (Fumarylacetoacetate hydrolase domain-containing protein 1) (FAH domain-containing protein 1) (Oxaloacetate decarboxylase) (OAA decarboxylase) (EC 4.1.1.112) (YisK-like protein)" FAHD1 C16orf36 YISKL Homo sapiens (Human) pyruvate metabolic process [GO:0006090] cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] acetylpyruvate hydrolase activity [GO:0018773]; acylpyruvate hydrolase activity [GO:0047621]; fumarylpyruvate hydrolase activity [GO:0034545]; metal ion binding [GO:0046872]; oxaloacetate decarboxylase activity [GO:0008948] 0.8796 0.018433 GIMAASRPLSR 0 0 0 0 0 0 0 0 0 8.19081 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6P597 KLC3_HUMAN Kinesin light chain 3 (KLC2-like) (kinesin light chain 2) KLC3 KLC2 KLC2L Homo sapiens (Human) axo-dendritic transport [GO:0008088]; microtubule-based movement [GO:0007018]; sperm mitochondrial sheath assembly [GO:0120317]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283] ciliary rootlet [GO:0035253]; cytoplasm [GO:0005737]; kinesin complex [GO:0005871]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; motile cilium [GO:0031514]; neuron projection [GO:0043005] kinesin binding [GO:0019894]; microtubule binding [GO:0008017] 0.78485 0.25614 VLGADHPDVAK 0 0 0 0 0 0 0 0 0 9.91358 8.93519 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6P5Q4 LMOD2_HUMAN Leiomodin-2 (Cardiac leiomodin) (C-LMOD) (Leiomodin) LMOD2 Homo sapiens (Human) actin filament polymerization [GO:0030041]; actin nucleation [GO:0045010]; muscle contraction [GO:0006936]; myofibril assembly [GO:0030239]; pointed-end actin filament capping [GO:0051694]; positive regulation of actin filament polymerization [GO:0030838]; sarcomere organization [GO:0045214] actin filament [GO:0005884]; M band [GO:0031430]; myofibril [GO:0030016]; sarcomere [GO:0030017] actin binding [GO:0003779]; actin monomer binding [GO:0003785]; tropomyosin binding [GO:0005523] 0.83554 0.18807 EALMAYWEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1169 0 0 0 0 0 0 0 0 0 0 10.5583 Q6P5S2 LEG1H_HUMAN Protein LEG1 homolog LEG1 C6orf58 Homo sapiens (Human) extracellular exosome [GO:0070062]; extracellular space [GO:0005615] 0.78166 0.26113 SIGYLCTEK 0 9.4591 9.47863 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6P5S7 RNK_HUMAN Ribonuclease kappa (RNase K) (RNase kappa) (EC 3.1.-.-) (V-type proton ATPase subunit f) (V-ATPase subunit f) RNASEK Homo sapiens (Human) endosomal lumen acidification [GO:0048388]; Golgi lumen acidification [GO:0061795]; intracellular pH reduction [GO:0051452]; lysosomal lumen acidification [GO:0007042]; proton transmembrane transport [GO:1902600]; receptor-mediated endocytosis [GO:0006898]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; vacuolar acidification [GO:0007035] "clathrin-coated vesicle membrane [GO:0030665]; endomembrane system [GO:0012505]; membrane [GO:0016020]; proton-transporting V-type ATPase complex [GO:0033176]; vacuolar proton-transporting V-type ATPase, V0 domain [GO:0000220]" RNA endonuclease activity [GO:0004521] 0.41967 0.67562 RSPTPFFMASLLCCGPK 0 9.11405 0 0 9.05254 0 0 9.06985 0 0 0 9.68373 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6P5Z2 PKN3_HUMAN Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN-beta) (Protein-kinase C-related kinase 3) PKN3 PKNBETA Homo sapiens (Human) epithelial cell migration [GO:0010631]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] ATP binding [GO:0005524]; calcium-dependent protein kinase C activity [GO:0004698]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; small GTPase binding [GO:0031267] 0.9656 -2.2968 AKHQRGR 0 0 0 0 0 0 0 0 0 0 0 10.3681 0 9.1362 0 0 0 0 0 0 0 0 0 0 0 0 9.65648 Q6P656 CF161_HUMAN Cilia- and flagella-associated protein 161 CFAP161 C15orf26 Homo sapiens (Human) cilium assembly [GO:0060271] axonemal microtubule [GO:0005879]; motile cilium [GO:0031514] 0.86279 0.08996 AMEQAMGLDTQ 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2936 10.6293 0 0 0 0 0 0 0 0 0 0 Q6P6B1 ERIC5_HUMAN Glutamate-rich protein 5 ERICH5 C8orf47 Homo sapiens (Human) 0.71712 0.36469 VETDMENEK 8.68089 8.5821 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6P6C2 ALKB5_HUMAN RNA demethylase ALKBH5 (EC 1.14.11.53) (Alkylated DNA repair protein alkB homolog 5) (Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5) ALKBH5 ABH5 OFOXD1 Homo sapiens (Human) cell differentiation [GO:0030154]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; oxidative single-stranded RNA demethylation [GO:0035553]; regulation of mRNA stability [GO:0043488]; response to hypoxia [GO:0001666]; spermatogenesis [GO:0007283] cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 2-oxoglutarate-dependent dioxygenase activity [GO:0016706]; metal ion binding [GO:0046872]; mRNA N6-methyladenosine dioxygenase activity [GO:1990931]; oxidative RNA demethylase activity [GO:0035515]; RNA binding [GO:0003723] 0.88759 -0.39687 GLYNEHTVDR 0 0 0 0 0 0 0 10.2353 0 0 0 0 0 0 0 0 0 0 9.15881 0 9.11538 0 0 0 0 0 0 Q6P988 NOTUM_HUMAN Palmitoleoyl-protein carboxylesterase NOTUM (EC 3.1.1.98) (hNOTUM) NOTUM OK/SW-CL.30 Homo sapiens (Human) bone development [GO:0060348]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of Wnt signaling pathway [GO:0030178]; protein depalmitoleylation [GO:1990697]; regulation of bone mineralization [GO:0030500]; Wnt signaling pathway [GO:0016055] endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576] palmitoleyl hydrolase activity [GO:1990699]; phospholipase C activity [GO:0004629] 0.88698 -0.35456 LMSSRDWPR 0 0 8.09545 0 0 0 8.66242 0 8.77545 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6P996 PDXD1_HUMAN Pyridoxal-dependent decarboxylase domain-containing protein 1 (EC 4.1.1.-) PDXDC1 KIAA0251 Homo sapiens (Human) carboxylic acid metabolic process [GO:0019752] Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231] cadherin binding [GO:0045296]; carboxy-lyase activity [GO:0016831]; pyridoxal phosphate binding [GO:0030170] 0.89939 -0.64617 EAVKMLEDSQR 0 0 8.96792 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5929 0 9.6851 0 8.82435 0 Q6P9A3 ZN549_HUMAN Zinc finger protein 549 ZNF549 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.32558 0.78435 IHTGEKPYECGK 0 0 0 0 0 0 0 0 0 0 0 8.7255 0 0 0 0 0 0 0 0 0 0 0 9.69674 0 0 0 Q6P9B6 MEAK7_HUMAN "MTOR-associated protein MEAK7 (MEAK7) (MTOR associated protein, eak-7 homolog) (TBC/LysM-associated domain-containing protein 1) (TLD domain-containing protein 1)" MEAK7 KIAA1609 TLDC1 Homo sapiens (Human) negative regulation of oxidative stress-induced neuron death [GO:1903204]; positive regulation of protein localization to lysosome [GO:0150032]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127]; response to amino acid [GO:0043200]; response to insulin [GO:0032868]; response to nutrient levels [GO:0031667]; TOR signaling [GO:0031929] cytoplasm [GO:0005737]; cytosol [GO:0005829]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] 0.8984 -0.56805 EAPGPNPR 0 0 0 0 0 0 0 0 0 8.42719 0 0 0 0 0 0 0 0 0 8.51013 0 0 8.39111 0 0 0 0 Q6P9B9 INT5_HUMAN Integrator complex subunit 5 (Int5) INTS5 KIAA1698 Homo sapiens (Human) regulation of transcription elongation by RNA polymerase II [GO:0034243]; snRNA 3'-end processing [GO:0034472]; snRNA processing [GO:0016180] cytoplasm [GO:0005737]; cytosol [GO:0005829]; integrator complex [GO:0032039]; membrane [GO:0016020]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.84879 0.11459 GLLAALLGHWEASR 0 0 0 0 9.81826 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2081 0 0 0 0 0 0 Q6P9F0 CCD62_HUMAN Coiled-coil domain-containing protein 62 (Protein TSP-NY) (Protein aaa) CCDC62 Homo sapiens (Human) blastocyst hatching [GO:0001835]; cellular response to estradiol stimulus [GO:0071392]; positive regulation of transcription by RNA polymerase II [GO:0045944]; spermatid development [GO:0007286] acrosomal vesicle [GO:0001669]; nucleus [GO:0005634] nuclear estrogen receptor binding [GO:0030331]; nuclear receptor coactivator activity [GO:0030374] 0.8849 -0.29571 VLTLEERCSK 0 0 0 0 0 0 0 0 0 10.5709 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6P9F5 TRI40_HUMAN E3 ubiquitin ligase TRIM40 (EC 2.3.2.27) (Probable E3 NEDD8-protein ligase) (RING finger protein 35) TRIM40 RNF35 Homo sapiens (Human) innate immune response [GO:0045087]; negative regulation of cell growth [GO:0030308]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein localization to nucleus [GO:1900181]; protein neddylation [GO:0045116]; protein ubiquitination [GO:0016567] cytoplasm [GO:0005737]; IkappaB kinase complex [GO:0008385] ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.88525 -0.33322 DIAELQRLK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.30415 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6P9F7 LRC8B_HUMAN Volume-regulated anion channel subunit LRRC8B (Leucine-rich repeat-containing protein 8B) (T-cell activation leucine repeat-rich protein) (TA-LRRP) LRRC8B KIAA0231 UNQ6413/PRO21207 Homo sapiens (Human) monoatomic anion transmembrane transport [GO:0098656] cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; monoatomic ion channel complex [GO:0034702]; plasma membrane [GO:0005886] 0.92583 -0.96337 LPSAVSQLVNLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.66617 0 0 0 0 0 0 0 Q6P9G9 ZN449_HUMAN Zinc finger protein 449 (Zinc finger and SCAN domain-containing protein 19) ZNF449 ZSCAN19 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357]; spermatogonial cell division [GO:0007284] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96268 -2.5283 CTHCSKSFR 0 0 10.5149 0 0 0 10.5718 0 0 12.4181 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6P9H4 CNKR3_HUMAN Connector enhancer of kinase suppressor of ras 3 (Connector enhancer of KSR 3) (CNK homolog protein 3) (CNK3) (CNKSR family member 3) (Maguin-like protein) CNKSR3 MAGI1 Homo sapiens (Human) negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765] apical plasma membrane [GO:0016324]; cytoplasm [GO:0005737] 0.96122 -2.5603 GSESPNSFLDQESRRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.33805 9.27722 0 0 0 0 0 0 0 0 0 Q6PCB5 RSBNL_HUMAN Lysine-specific demethylase RSBN1L (EC 1.14.11.-) (Round spermatid basic protein 1-like protein) RSBN1L Homo sapiens (Human) nucleus [GO:0005634] dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872] 0.89716 -0.6734 KHKENEK 0 0 0 11.0723 0 0 0 12.7585 0 0 0 0 0 12.0508 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6PCB6 AB17C_HUMAN Alpha/beta hydrolase domain-containing protein 17C (Abhydrolase domain-containing protein 17C) (EC 3.1.2.22) ABHD17C FAM108C1 Homo sapiens (Human) negative regulation of protein localization to microtubule [GO:1902817]; positive regulation of protein localization to endosome [GO:1905668]; protein depalmitoylation [GO:0002084]; regulation of postsynapse organization [GO:0099175] dendritic spine [GO:0043197]; endosome membrane [GO:0010008]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; recycling endosome membrane [GO:0055038] palmitoyl-(protein) hydrolase activity [GO:0008474] 0.89927 -0.61525 ELDAVEVFFSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.56274 0 0 0 0 0 0 0 0 Q6PCB7 S27A1_HUMAN Long-chain fatty acid transport protein 1 (Arachidonate--CoA ligase) (EC 6.2.1.15) (Fatty acid transport protein 1) (FATP-1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 1) (Very long-chain acyl-CoA synthetase) (EC 6.2.1.-) SLC27A1 ACSVL5 FATP1 Homo sapiens (Human) adiponectin-activated signaling pathway [GO:0033211]; biotin import across plasma membrane [GO:1905135]; biotin transport [GO:0015878]; cardiolipin biosynthetic process [GO:0032049]; export across plasma membrane [GO:0140115]; glucose import in response to insulin stimulus [GO:0044381]; lipid transport across blood-brain barrier [GO:1990379]; long-chain fatty acid import across plasma membrane [GO:0015911]; long-chain fatty acid import into cell [GO:0044539]; long-chain fatty acid transport [GO:0015909]; medium-chain fatty acid transport [GO:0001579]; negative regulation of phospholipid biosynthetic process [GO:0071072]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylcholine biosynthetic process [GO:0006656]; phosphatidylethanolamine biosynthetic process [GO:0006646]; phosphatidylglycerol biosynthetic process [GO:0006655]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylserine biosynthetic process [GO:0006659]; positive regulation of heat generation [GO:0031652]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of triglyceride biosynthetic process [GO:0010867]; response to cold [GO:0009409]; response to insulin [GO:0032868]; transport across blood-brain barrier [GO:0150104] basal plasma membrane [GO:0009925]; endoplasmic reticulum [GO:0005783]; membrane [GO:0016020]; plasma membrane [GO:0005886] arachidonate-CoA ligase activity [GO:0047676]; biotin transmembrane transporter activity [GO:0015225]; efflux transmembrane transporter activity [GO:0015562]; fatty acid transmembrane transporter activity [GO:0015245]; identical protein binding [GO:0042802]; long-chain fatty acid transporter activity [GO:0005324]; long-chain fatty acid-CoA ligase activity [GO:0004467]; nucleotide binding [GO:0000166]; oleate transmembrane transporter activity [GO:1901480]; oleoyl-CoA ligase activity [GO:0090434]; very long-chain fatty acid-CoA ligase activity [GO:0031957] 0.92995 -1.2409 MAAFGHHAYR 0 9.29735 0 0 0 0 0 0 10.1165 0 0 9.77569 0 0 10.9709 11.5621 0 0 0 0 0 0 0 0 0 0 0 Q6PCD5 RFWD3_HUMAN E3 ubiquitin-protein ligase RFWD3 (EC 2.3.2.27) (RING finger and WD repeat domain-containing protein 3) (RING finger protein 201) RFWD3 RNF201 Homo sapiens (Human) DNA damage response [GO:0006974]; double-strand break repair via homologous recombination [GO:0000724]; interstrand cross-link repair [GO:0036297]; mitotic G1 DNA damage checkpoint signaling [GO:0031571]; protein ubiquitination [GO:0016567]; regulation of DNA damage checkpoint [GO:2000001]; replication fork processing [GO:0031297]; response to ionizing radiation [GO:0010212] cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; site of DNA damage [GO:0090734] MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; ubiquitin protein ligase activity [GO:0061630] 0.92001 -1.1429 AASAAFPYGGVLAGTLEDASFWEQK 0 10.8976 0 0 0 0 0 0 0 10.3157 0 10.925 0 10.7533 0 0 0 0 0 0 9.79022 0 0 0 0 0 0 Q6PCT2 FXL19_HUMAN F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19) FBXL19 FBL19 Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein demethylation [GO:0006482]; regulation of transcription by RNA polymerase II [GO:0006357] cytoplasm [GO:0005737]; cytosol [GO:0005829]; SCF ubiquitin ligase complex [GO:0019005] histone demethylase activity [GO:0032452]; transcription coregulator activity [GO:0003712]; ubiquitin ligase-substrate adaptor activity [GO:1990756]; unmethylated CpG binding [GO:0045322]; zinc ion binding [GO:0008270] 0.96778 -2.8968 AAWLRVFQHLGPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0415 0 0 0 0 0 0 0 Q6PD62 CTR9_HUMAN RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) CTR9 KIAA0155 SH2BP1 Homo sapiens (Human) blastocyst growth [GO:0001832]; blastocyst hatching [GO:0001835]; cellular response to lipopolysaccharide [GO:0071222]; endodermal cell fate commitment [GO:0001711]; histone modification [GO:0016570]; inner cell mass cell differentiation [GO:0001826]; interleukin-6-mediated signaling pathway [GO:0070102]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of genetic imprinting [GO:2000653]; regulation of histone H3-K4 methylation [GO:0051569]; stem cell population maintenance [GO:0019827]; transcription elongation by RNA polymerase II [GO:0006368]; trophectodermal cell differentiation [GO:0001829]; Wnt signaling pathway [GO:0016055] Cdc73/Paf1 complex [GO:0016593]; euchromatin [GO:0000791]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654] RNA polymerase II complex binding [GO:0000993]; SH2 domain binding [GO:0042169] 0.91394 -0.78272 DYRGALAYYK 0 0 8.69905 0 0 0 8.68011 0 0 0 0 8.68243 0 0 0 0 0 0 0 0 0 9.78707 10.289 0 0 0 10.6349 Q6PDB4 ZN880_HUMAN Zinc finger protein 880 ZNF880 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.92386 -1.0494 LGSNAGNKSLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.72197 0 0 Q6PEX7 TEX38_HUMAN Testis-expressed protein 38 (ATPAF1 antisense RNA 1) (ATPAF1 antisense gene protein 1) TEX38 ATPAF1-AS1 C1orf223 Homo sapiens (Human) membrane [GO:0016020] 0.87074 0.059747 AATFTYSPLLYWINK 0 0 0 0 0 0 0 0 11.5967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6PEY0 CXB7_HUMAN Gap junction beta-7 protein (Connexin-25) (Cx25) GJB7 CX25 Homo sapiens (Human) cell-cell signaling [GO:0007267]; transmembrane transport [GO:0055085] connexin complex [GO:0005922] gap junction channel activity [GO:0005243] 0.96919 -3.3761 EFECNSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.38965 0 0 0 0 0 0 0 Q6PEZ8 PONL1_HUMAN Podocan-like protein 1 PODNL1 SLRR5B Homo sapiens (Human) extracellular space [GO:0005615] 0.95472 -1.5713 VPPALPR 0 0 0 0 11.4851 0 0 0 0 0 12.3579 0 0 0 0 0 0 0 0 0 0 0 11.4367 0 0 0 0 Q6PF05 TT23L_HUMAN Tetratricopeptide repeat protein 23-like TTC23L Homo sapiens (Human) response to endoplasmic reticulum stress [GO:0034976] cytoplasm [GO:0005737]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; spindle [GO:0005819] 0.92219 -1.1354 EKMNTQANKELIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3876 0 0 Q6PF06 TM10B_HUMAN tRNA methyltransferase 10 homolog B (EC 2.1.1.221) (RNA (guanine-9-)-methyltransferase domain-containing protein 3) (tRNA (guanine(9)-N(1))-methyltransferase TRMT10B) TRMT10B RG9MTD3 Homo sapiens (Human) protein insertion into mitochondrial inner membrane [GO:0045039]; tRNA N1-guanine methylation [GO:0002939] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; TIM22 mitochondrial import inner membrane insertion complex [GO:0042721] tRNA (guanine(9)-N(1))-methyltransferase activity [GO:0052905]; tRNA (guanine-N1-)-methyltransferase activity [GO:0009019]; tRNA binding [GO:0000049] 0.91543 -0.79052 AENPGICPQHSKR 0 0 0 0 0 0 0 0 8.69978 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6PFW1 VIP1_HUMAN Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 (EC 2.7.4.24) (Diphosphoinositol pentakisphosphate kinase 1) (Histidine acid phosphatase domain-containing protein 2A) (IP6 kinase) (Inositol pyrophosphate synthase 1) (InsP6 and PP-IP5 kinase 1) (VIP1 homolog) (hsVIP1) PPIP5K1 HISPPD2A IP6K IPS1 KIAA0377 VIP1 Homo sapiens (Human) inositol metabolic process [GO:0006020]; inositol phosphate biosynthetic process [GO:0032958]; inositol phosphate metabolic process [GO:0043647]; phosphorylation [GO:0016310] cytosol [GO:0005829]; plasma membrane [GO:0005886] "ATP binding [GO:0005524]; diphosphoinositol-pentakisphosphate kinase activity [GO:0033857]; inositol heptakisphosphate kinase activity [GO:0000829]; inositol hexakisphosphate 1-kinase activity [GO:0052723]; inositol hexakisphosphate 3-kinase activity [GO:0052724]; inositol hexakisphosphate 5-kinase activity [GO:0000832]; inositol hexakisphosphate kinase activity [GO:0000828]; inositol-1,3,4,5,6-pentakisphosphate kinase activity [GO:0000827]" 0.95186 -1.3838 QVSEFLSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.2042 0 0 0 0 0 0 0 0 0 0 0 0 Q6PG37 ZN790_HUMAN Zinc finger protein 790 ZNF790 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.88371 -0.16412 AFSCGSDLTRHQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.6153 0 0 0 0 0 0 0 0 0 Q6PGN9 PSRC1_HUMAN Proline/serine-rich coiled-coil protein 1 PSRC1 DDA3 FP3214 Homo sapiens (Human) cell division [GO:0051301]; microtubule bundle formation [GO:0001578]; mitotic metaphase plate congression [GO:0007080]; negative regulation of cell growth [GO:0030308]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of microtubule polymerization [GO:0031116]; regulation of mitotic spindle organization [GO:0060236] cytoplasm [GO:0005737]; cytosol [GO:0005829]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; spindle [GO:0005819]; spindle pole [GO:0000922] microtubule binding [GO:0008017] 0.94432 -1.3389 GRAGPSGRAAASEETR 0 11.4325 0 0 0 11.1597 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6PGP7 SKI3_HUMAN Superkiller complex protein 3 (Ski3) (Tetratricopeptide repeat protein 37) (TPR repeat protein 37) (Tricho-hepatic-enteric syndrome protein) (Thespin) SKIC3 KIAA0372 TTC37 Homo sapiens (Human) "nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay [GO:0070478]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; rescue of stalled ribosome [GO:0072344]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Ski complex [GO:0055087] 0.96713 -3.7529 AARLDTYMGKVFCYLGHYYR 0 9.85384 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6PGQ7 BORA_HUMAN Protein aurora borealis (HsBora) BORA C13orf34 Homo sapiens (Human) activation of protein kinase activity [GO:0032147]; cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic nuclear division [GO:0007088]; regulation of mitotic spindle organization [GO:0060236]; regulation of protein localization [GO:0032880] cytoplasm [GO:0005737]; cytosol [GO:0005829]; meiotic spindle [GO:0072687]; nucleus [GO:0005634] protein kinase binding [GO:0019901] 0.96808 -2.8861 CWMKTASPFQCSSP 0 0 0 0 0 9.07756 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.71153 0 0 0 0 Q6PHR2 ULK3_HUMAN Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3) ULK3 Homo sapiens (Human) autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; cellular senescence [GO:0090398]; fibroblast activation [GO:0072537]; late nucleophagy [GO:0044805]; negative regulation of smoothened signaling pathway [GO:0045879]; peptidyl-serine phosphorylation [GO:0018105]; piecemeal microautophagy of the nucleus [GO:0034727]; positive regulation of smoothened signaling pathway [GO:0045880]; protein autophosphorylation [GO:0046777]; regulation of autophagy [GO:0010506]; reticulophagy [GO:0061709]; smoothened signaling pathway [GO:0007224] autophagosome [GO:0005776]; ciliary tip [GO:0097542]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; phagophore assembly site [GO:0000407] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.88283 -0.27192 LGSGTYATVYK 10.2303 0 10.2788 0 0 0 0 0 0 0 0 8.97688 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6PI26 SHQ1_HUMAN Protein SHQ1 homolog SHQ1 Homo sapiens (Human) box H/ACA snoRNP assembly [GO:0000493]; negative regulation of rRNA processing [GO:2000233]; positive regulation of apoptotic process [GO:0043065]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; ribonucleoprotein complex assembly [GO:0022618] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654] unfolded protein binding [GO:0051082] 0.77182 0.27315 CLLDIHK 0 0 0 0 0 0 12.5065 0 12.3763 0 0 0 0 11.5757 11.6814 0 0 0 0 0 0 0 0 0 0 0 0 Q6PI47 KCD18_HUMAN BTB/POZ domain-containing protein KCTD18 KCTD18 Homo sapiens (Human) protein homooligomerization [GO:0051260] 0.9565 -1.5424 AAQRSAPSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.85123 0 0 0 0 Q6PI98 IN80C_HUMAN INO80 complex subunit C (IES6 homolog) (hIes6) INO80C C18orf37 Homo sapiens (Human) chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of telomere maintenance in response to DNA damage [GO:1904507]; regulation of cell cycle [GO:0051726]; regulation of chromosome organization [GO:0033044]; regulation of DNA repair [GO:0006282]; regulation of DNA replication [GO:0006275]; regulation of DNA strand elongation [GO:0060382]; regulation of embryonic development [GO:0045995]; telomere maintenance [GO:0000723] Ino80 complex [GO:0031011]; MLL1 complex [GO:0071339]; nucleoplasm [GO:0005654] 0.49068 0.61771 KRPASPSHNGSSGGGYGASK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.78516 0 0 Q6PIF2 SYCE2_HUMAN Synaptonemal complex central element protein 2 (Central element synaptonemal complex protein 1) SYCE2 CESC1 Homo sapiens (Human) cell division [GO:0051301]; synaptonemal complex assembly [GO:0007130] central element [GO:0000801]; chromosome [GO:0005694]; nucleoplasm [GO:0005654] 0.72096 0.36399 LQEFTQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.84024 0 0 0 0 0 Q6PIF6 MYO7B_HUMAN Unconventional myosin-VIIb MYO7B Homo sapiens (Human) actin filament organization [GO:0007015]; brush border assembly [GO:1904970]; cell differentiation [GO:0030154]; sensory organ development [GO:0007423]; sensory perception of sound [GO:0007605]; vesicle transport along actin filament [GO:0030050] actin cytoskeleton [GO:0015629]; apical cytoplasm [GO:0090651]; brush border [GO:0005903]; cytoplasm [GO:0005737]; microvillus [GO:0005902]; myosin complex [GO:0016459]; vesicle [GO:0031982] actin filament binding [GO:0051015]; ATP binding [GO:0005524]; cytoskeletal motor activity [GO:0003774] 0.96993 -5.2204 EVSDWVKK 0 0 0 10.044 0 10.3079 0 0 0 0 0 0 0 0 0 0 10.8612 0 0 0 8.59511 0 0 0 0 10.8187 0 Q6PIJ6 FBX38_HUMAN F-box only protein 38 FBXO38 SP329 Homo sapiens (Human) adaptive immune response [GO:0002250]; positive regulation of neuron projection development [GO:0010976]; positive regulation of T cell mediated immune response to tumor cell [GO:0002842]; protein K48-linked ubiquitination [GO:0070936]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005] 0.89742 -0.68041 GSSQPESCDVQSNEDYPR 0 0 0 0 8.49753 9.24213 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6PIL6 KCIP4_HUMAN Kv channel-interacting protein 4 (KChIP4) (A-type potassium channel modulatory protein 4) (Calsenilin-like protein) (Potassium channel-interacting protein 4) KCNIP4 CALP KCHIP4 Homo sapiens (Human) protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transmembrane transport [GO:1901379] cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; neuronal cell body [GO:0043025]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076] calcium ion binding [GO:0005509]; potassium channel activity [GO:0005267]; potassium channel regulator activity [GO:0015459]; voltage-gated monoatomic ion channel activity [GO:0005244] 0.91582 -0.769 GLSILLRGTVQEK 0 9.75647 0 0 9.81144 0 0 0 11.2929 0 0 10.8789 0 0 11.421 0 0 0 0 0 0 0 0 0 0 0 0 Q6PIU1 KCNV1_HUMAN Potassium voltage-gated channel subfamily V member 1 (Neuronal potassium channel alpha subunit HNKA) (Voltage-gated potassium channel subunit Kv8.1) KCNV1 Homo sapiens (Human) potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of monoatomic ion transmembrane transport [GO:0034765] intercellular bridge [GO:0045171]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076] ion channel inhibitor activity [GO:0008200]; potassium channel regulator activity [GO:0015459]; voltage-gated potassium channel activity [GO:0005249] 0.96909 -4.8602 FLCVRDR 0 0 0 0 0 0 0 0 0 0 0 0 0 8.98695 0 0 0 0 0 0 0 0 9.11207 0 0 0 0 Q6PIV2 FOXR1_HUMAN Forkhead box protein R1 (Forkhead box protein N5) FOXR1 FOXN5 DLNB13 Homo sapiens (Human) brain development [GO:0007420]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.93224 -1.2864 LEVSGRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.0474 0 0 Q6PIW4 FIGL1_HUMAN Fidgetin-like protein 1 (EC 3.6.4.-) FIGNL1 Homo sapiens (Human) ATP metabolic process [GO:0046034]; cellular response to ionizing radiation [GO:0071479]; male meiotic nuclear division [GO:0007140]; negative regulation of apoptotic process [GO:0043066]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; regulation of cell cycle [GO:0051726]; regulation of double-strand break repair via homologous recombination [GO:0010569] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nuclear chromosome [GO:0000228]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; hydrolase activity [GO:0016787]; magnesium ion binding [GO:0000287]; microtubule severing ATPase activity [GO:0008568] 0.87402 0.026722 ENIGLNVFLSNQSCFPAACENPQR 0 0 0 0 0 9.2559 0 0 0 0 0 0 0 0 0 0 0 0 9.83883 0 0 0 0 0 0 0 0 Q6PIY7 GLD2_HUMAN Poly(A) RNA polymerase GLD2 (hGLD-2) (EC 2.7.7.19) (PAP-associated domain-containing protein 4) (Terminal nucleotidyltransferase 2) (Terminal uridylyltransferase 2) (TUTase 2) TENT2 GLD2 PAPD4 Homo sapiens (Human) dark adaptation [GO:1990603]; hematopoietic progenitor cell differentiation [GO:0002244]; hippocampus development [GO:0021766]; histone mRNA catabolic process [GO:0071044]; mRNA polyadenylation [GO:0006378]; negative regulation of miRNA catabolic process [GO:2000626]; neuron differentiation [GO:0030182]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of translation at postsynapse [GO:0140245]; retina development in camera-type eye [GO:0060041]; RNA polyadenylation [GO:0043631]; RNA polyadenylation at postsynapse [GO:0140235] cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; nuclear RNA-directed RNA polymerase complex [GO:0031380]; perforant pathway to dendrate granule cell synapse [GO:0140240]; postsynapse [GO:0098794] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; poly(A) RNA polymerase activity [GO:1990817]; translation regulator activity [GO:0045182] 0.96847 -6.5748 DQFLKSWHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3415 0 10.9194 0 0 0 0 0 0 Q6PJ61 FBX46_HUMAN F-box only protein 46 (F-box only protein 34-like) FBXO46 FBX46 FBXO34L Homo sapiens (Human) 0.96307 -2.6619 DDPCKQCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.58256 0 0 0 Q6PJE2 POZP3_HUMAN POM121 and ZP3 fusion protein (POM-ZP3) POMZP3 Homo sapiens (Human) nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654] 0.7637 0.2972 NMIYITCHLK 0 0 8.70591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6PJF5 RHDF2_HUMAN Inactive rhomboid protein 2 (iRhom2) (Rhomboid 5 homolog 2) (Rhomboid family member 2) (Rhomboid veinlet-like protein 5) (Rhomboid veinlet-like protein 6) RHBDF2 IRHOM2 RHBDL5 RHBDL6 Homo sapiens (Human) negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of protein secretion [GO:0050709]; protein localization to plasma membrane [GO:0072659]; protein transport [GO:0015031]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of metalloendopeptidase activity [GO:1904683]; regulation of protein secretion [GO:0050708] endoplasmic reticulum membrane [GO:0005789]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886] growth factor binding [GO:0019838]; protein transporter activity [GO:0140318]; serine-type endopeptidase activity [GO:0004252] 0.80094 0.23921 GVYESVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.66828 Q6PJG2 MDEAS_HUMAN Mitotic deacetylase-associated SANT domain protein (ELM2 and SANT domain-containing protein 1) MIDEAS C14orf117 C14orf43 ELMSAN1 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; regulation of transcription by RNA polymerase II [GO:0006357] histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; transcription regulator complex [GO:0005667] DNA binding [GO:0003677]; transcription corepressor activity [GO:0003714] 0.95886 -1.7761 DGSGSEEK 8.55459 9.18093 0 0 0 0 12.6389 0 0 0 0 10.4323 0 0 0 12.0746 0 12.4742 0 0 0 0 0 0 0 0 0 Q6PJG9 LRFN4_HUMAN Leucine-rich repeat and fibronectin type-III domain-containing protein 4 LRFN4 SALM3 Homo sapiens (Human) regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]; synaptic membrane adhesion [GO:0099560] cell surface [GO:0009986]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839] 0.58984 0.46048 GVGGSAER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.56685 7.82839 0 8.73779 8.6709 8.64339 0 0 Q6PJP8 DCR1A_HUMAN DNA cross-link repair 1A protein (Beta-lactamase DCLRE1A) (EC 3.5.2.6) (SNM1 homolog A) (hSNM1) (hSNM1A) DCLRE1A KIAA0086 SNM1 SNM1A Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; double-strand break repair via nonhomologous end joining [GO:0006303]; interstrand cross-link repair [GO:0036297] fibrillar center [GO:0001650]; nucleoplasm [GO:0005654] 5'-3' DNA exonuclease activity [GO:0035312]; beta-lactamase activity [GO:0008800]; damaged DNA binding [GO:0003684]; metal ion binding [GO:0046872] 0.92007 -0.92726 EEKLLGESALEGINLNPVPSPNQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6578 0 0 0 8.98826 0 9.34341 0 0 0 0 10.2807 10.706 Q6PJQ5 FOXR2_HUMAN Forkhead box protein R2 (Forkhead box protein N6) FOXR2 FOXN6 Homo sapiens (Human) chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.88313 -0.26997 CYQSQKLWQINNQEK 0 0 0 0 0 0 0 0 0 0 0 10.0843 0 0 0 0 0 0 0 10.0251 0 0 0 0 0 0 0 Q6PJT7 ZC3HE_HUMAN Zinc finger CCCH domain-containing protein 14 (Mammalian suppressor of tau pathology-2) (MSUT-2) (Renal carcinoma antigen NY-REN-37) ZC3H14 Homo sapiens (Human) negative regulation of mRNA polyadenylation [GO:1900364]; regulation of mRNA stability [GO:0043488] axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; dendrite cytoplasm [GO:0032839]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] metal ion binding [GO:0046872]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723] 0.89752 -0.53737 AISEAQESVTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.30209 0 0 0 0 0 0 0 0 0 0 Q6PJW8 CNST_HUMAN Consortin CNST C1orf71 Homo sapiens (Human) positive regulation of Golgi to plasma membrane protein transport [GO:0042998] intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; trans-Golgi network [GO:0005802]; transport vesicle [GO:0030133] connexin binding [GO:0071253]; phosphatase binding [GO:0019902] 0.6231 0.4137 CSTQLLVSEDPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.98905 0 0 0 0 0 0 0 0 0 0 9.14736 Q6PK04 CC137_HUMAN Coiled-coil domain-containing protein 137 CCDC137 cPERP-B Homo sapiens (Human) chromosome [GO:0005694]; fibrillar center [GO:0001650]; nucleolus [GO:0005730]; nucleus [GO:0005634] RNA binding [GO:0003723] 0.96856 -7.8522 EIMRSRQEMK 0 0 11.8099 0 0 0 0 0 0 0 0 0 0 0 9.22617 11.8315 0 0 0 0 0 0 0 9.07692 0 0 0 Q6PKC3 TXD11_HUMAN Thioredoxin domain-containing protein 11 (EF-hand-binding protein 1) TXNDC11 EFP1 Homo sapiens (Human) endoplasmic reticulum membrane [GO:0005789] 0.69892 0.3738 DEHRLRQQQR 0 0 0 0 0 0 0 0 0 9.28981 9.15709 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6PKG0 LARP1_HUMAN La-related protein 1 (La ribonucleoprotein domain family member 1) LARP1 KIAA0731 LARP Homo sapiens (Human) cell population proliferation [GO:0008283]; cellular response to rapamycin [GO:0072752]; mRNA stabilization [GO:0048255]; negative regulation of translation [GO:0017148]; negative regulation of translational initiation [GO:0045947]; positive regulation of macroautophagy [GO:0016239]; positive regulation of translation [GO:0045727]; positive regulation of translational initiation [GO:0045948]; positive regulation of viral genome replication [GO:0045070]; post-transcriptional regulation of gene expression [GO:0010608]; response to amino acid starvation [GO:1990928]; TOR signaling [GO:0031929]; TORC1 signaling [GO:0038202]; translational initiation [GO:0006413] cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; membrane [GO:0016020] cadherin binding [GO:0045296]; eukaryotic initiation factor 4E binding [GO:0008190]; mRNA 3'-UTR binding [GO:0003730]; mRNA 5'-UTR binding [GO:0048027]; ribosomal small subunit binding [GO:0043024]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]; translation activator activity [GO:0008494]; translation initiation factor binding [GO:0031369] 0.9682 -9.5709 FEPEYSQIKQEVENFKK 0 9.71886 0 0 0 0 0 0 0 0 0 0 10.625 10.9156 0 0 0 0 0 0 0 10.0296 0 0 0 0 10.4262 Q6PKX4 DOK6_HUMAN Docking protein 6 (Downstream of tyrosine kinase 6) DOK6 DOK5L Homo sapiens (Human) positive regulation of MAPK cascade [GO:0043410]; Ras protein signal transduction [GO:0007265]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] cytoplasm [GO:0005737]; cytosol [GO:0005829] 0.96771 -3.6664 LEKFPDEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.9418 0 0 0 0 0 0 Q6PL18 ATAD2_HUMAN ATPase family AAA domain-containing protein 2 (EC 3.6.1.-) (AAA nuclear coregulator cancer-associated protein) (ANCCA) ATAD2 L16 PRO2000 Homo sapiens (Human) positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944] extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; chromatin binding [GO:0003682]; histone binding [GO:0042393] 0.96422 -2.2684 DIDLICSNALEYNPDR 9.83883 0 0 0 0 0 10.2279 0 0 0 0 0 0 0 0 0 9.18735 0 0 8.61342 0 0 0 0 0 0 9.15008 Q6PML9 ZNT9_HUMAN "Proton-coupled zinc antiporter SLC30A9, mitochondrial (Human embryonic lung protein) (HuEL) (Solute carrier family 30 member 9) (Zinc transporter 9) (ZnT-9)" SLC30A9 C4orf1 HUEL Homo sapiens (Human) intracellular zinc ion homeostasis [GO:0006882]; nucleotide-excision repair [GO:0006289]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of mitochondrion organization [GO:0010821]; zinc ion transport [GO:0006829] cytoplasmic vesicle [GO:0031410]; cytoskeleton [GO:0005856]; endoplasmic reticulum [GO:0005783]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634] antiporter activity [GO:0015297]; chromatin binding [GO:0003682]; nuclear receptor binding [GO:0016922]; nuclear receptor coactivator activity [GO:0030374]; zinc ion transmembrane transporter activity [GO:0005385] 0.96039 -1.8066 GMSFYKYVMESR 0 0 0 0 0 0 0 0 0 9.68004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3167 Q6PRD1 GP179_HUMAN Probable G-protein coupled receptor 179 (Probable G-protein coupled receptor 158-like 1) (GPR158-like) GPR179 GPR158L GPR158L1 Homo sapiens (Human) visual perception [GO:0007601] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930] 0.96943 -5.7154 AGPGGTEEHFSK 0 0 0 0 0 0 0 0 0 0 0 0 9.06633 0 0 0 0 8.97625 0 10.5511 0 0 0 0 0 0 0 Q6PRD7 CEMP1_HUMAN Cementoblastoma-derived protein 1 (Cementum protein 1) (Cementum protein 23) (CP-23) CEMP1 Homo sapiens (Human) biomineral tissue development [GO:0031214]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; odontogenesis [GO:0042476] cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] hydroxyapatite binding [GO:0046848] 0.80893 0.23219 AEVGIPAPHTSQEVR 0 0 0 0 0 0 0 0 0 0 0 0 9.59362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6PUV4 CPLX2_HUMAN Complexin-2 (Complexin II) (CPX II) (Synaphin-1) CPLX2 Homo sapiens (Human) cell differentiation [GO:0030154]; mast cell degranulation [GO:0043303]; nervous system development [GO:0007399]; positive regulation of synaptic plasticity [GO:0031915]; regulation of exocytosis [GO:0017157]; regulation of neurotransmitter secretion [GO:0046928]; regulation of synaptic vesicle fusion to presynaptic active zone membrane [GO:0031630]; synaptic vesicle exocytosis [GO:0016079]; vesicle docking involved in exocytosis [GO:0006904] calyx of Held [GO:0044305]; cytosol [GO:0005829]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; nucleus [GO:0005634]; perikaryon [GO:0043204]; postsynapse [GO:0098794]; SNARE complex [GO:0031201]; synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex [GO:0070033]; synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex [GO:0070554]; terminal bouton [GO:0043195] calcium-dependent protein binding [GO:0048306]; SNARE binding [GO:0000149]; syntaxin-1 binding [GO:0017075] 0.95216 -1.4769 QEALRQQEEER 0 0 0 0 0 0 11.625 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6Q0C1 S2547_HUMAN Solute carrier family 25 member 47 (Hepatocellular carcinoma down-regulated mitochondrial carrier protein) SLC25A47 C14orf68 HDMCP HMFN1655 Homo sapiens (Human) mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] transmembrane transporter activity [GO:0022857] 0.40092 0.70363 AFPVNMVVFVAYEAVLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.9767 0 15.1176 0 Q6Q4G3 AMPQ_HUMAN Aminopeptidase Q (AP-Q) (APQ) (EC 3.4.11.-) (CHL2 antigen) (Laeverin) LVRN AQPEP Homo sapiens (Human) peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] cytoplasm [GO:0005737]; membrane [GO:0016020] metalloaminopeptidase activity [GO:0070006]; peptide binding [GO:0042277]; zinc ion binding [GO:0008270] 0.78604 0.25468 DLEAESSPPLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.75183 0 0 10.6703 Q6Q759 SPG17_HUMAN Sperm-associated antigen 17 (Projection protein PF6 homolog) SPAG17 Homo sapiens (Human) axonemal central apparatus assembly [GO:1904158]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; intramanchette transport [GO:1990953]; manchette assembly [GO:1905198]; motile cilium assembly [GO:0044458]; spermatogenesis [GO:0007283] acrosomal vesicle [GO:0001669]; axonemal central apparatus [GO:1990716]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; manchette [GO:0002177]; microtubule [GO:0005874]; motile cilium [GO:0031514] 0.96905 -13.074 DYINYILK 0 0 0 0 0 0 9.5751 0 0 9.03988 0 0 0 0 0 0 10.3708 0 11.8548 9.13096 12.4953 0 0 0 0 0 0 Q6Q788 APOA5_HUMAN Apolipoprotein A-V (Apo-AV) (ApoA-V) (Apolipoprotein A5) (Regeneration-associated protein 3) APOA5 RAP3 UNQ411/PRO773 Homo sapiens (Human) acylglycerol homeostasis [GO:0055090]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; lipid transport [GO:0006869]; lipoprotein metabolic process [GO:0042157]; phospholipid efflux [GO:0033700]; positive regulation of fatty acid biosynthetic process [GO:0045723]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of lipoprotein lipase activity [GO:0051006]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of triglyceride catabolic process [GO:0010898]; positive regulation of very-low-density lipoprotein particle remodeling [GO:0010902]; tissue regeneration [GO:0042246]; triglyceride catabolic process [GO:0019433]; triglyceride homeostasis [GO:0070328]; triglyceride metabolic process [GO:0006641]; very-low-density lipoprotein particle remodeling [GO:0034372] chylomicron [GO:0042627]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; high-density lipoprotein particle [GO:0034364]; late endosome [GO:0005770]; very-low-density lipoprotein particle [GO:0034361] enzyme activator activity [GO:0008047]; enzyme binding [GO:0019899]; heparin binding [GO:0008201]; lipase activator activity [GO:0060229]; lipase binding [GO:0035473]; lipid binding [GO:0008289]; lipoprotein lipase activator activity [GO:0060230]; lipoprotein particle receptor binding [GO:0070325]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylcholine binding [GO:0031210]; phosphatidylcholine-sterol O-acyltransferase activator activity [GO:0060228]; phospholipid binding [GO:0005543] 0.8428 0.15 IQQNLDQLR 0 0 0 0 0 0 0 0 0 8.7129 0 0 0 0 0 0 0 0 0 9.13235 0 0 0 0 0 0 0 Q6Q795 VBPC1_HUMAN Putative viral protein-binding protein C1 Homo sapiens (Human) protein-containing complex [GO:0032991] 0.89842 -0.56805 GLALPWDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.2565 0 0 0 0 0 0 0 0 0 0 0 0 Q6QHF9 PAOX_HUMAN Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (EC 1.5.3.13) (Polyamine oxidase) PAOX PAO UNQ1923/PRO4398 Homo sapiens (Human) polyamine catabolic process [GO:0006598]; positive regulation of spermidine biosynthetic process [GO:1901307]; putrescine biosynthetic process [GO:0009446]; putrescine catabolic process [GO:0009447]; spermidine catabolic process [GO:0046203]; spermine catabolic process [GO:0046208] cytosol [GO:0005829]; peroxisomal matrix [GO:0005782] "N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity [GO:0052899]; N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity [GO:0052904]; N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity [GO:0052903]; polyamine oxidase activity [GO:0046592]; spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity [GO:0052902]; spermine:oxygen oxidoreductase (spermidine-forming) activity [GO:0052901]" 0.89007 -0.47548 EIGQHVAGWTEDEETRK 0 0 0 0 0 0 0 0 0 0 9.59591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6QNK2 AGRD1_HUMAN Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) (G-protein coupled receptor PGR25) ADGRD1 GPR133 PGR25 Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930] 0.54729 0.57144 GVTLLYYGR 0 0 9.92567 0 0 0 10.719 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6QNY1 BL1S2_HUMAN Biogenesis of lysosome-related organelles complex 1 subunit 2 (BLOC-1 subunit 2) (Centrosome-associated protein) BLOC1S2 BLOS2 CEAP Homo sapiens (Human) anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; endosomal transport [GO:0016197]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; lysosome localization [GO:0032418]; melanosome organization [GO:0032438]; microtubule nucleation [GO:0007020]; mitochondrial outer membrane permeabilization [GO:0097345]; neuron projection development [GO:0031175]; organelle transport along microtubule [GO:0072384]; platelet dense granule organization [GO:0060155]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of endosome size [GO:0051036]; regulation of lysosome size [GO:0062196] axon cytoplasm [GO:1904115]; BLOC-1 complex [GO:0031083]; BORC complex [GO:0099078]; centrosome [GO:0005813]; cytoplasmic side of lysosomal membrane [GO:0098574]; cytosol [GO:0005829]; gamma-tubulin complex [GO:0000930]; mitochondrion [GO:0005739]; nucleus [GO:0005634] gamma-tubulin binding [GO:0043015] 0.87046 0.050067 DDAAVETAEEAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.18021 0 0 0 0 0 0 0 0 Q6R2W3 SCND3_HUMAN SCAN domain-containing protein 3 (Transposon-derived Buster4 transposase-like protein) (Zinc finger BED domain-containing protein 9) SCAND3 Buster4 KIAA1925 ZBED9 ZNF305P2 ZNF452 Homo sapiens (Human) DNA integration [GO:0015074]; positive regulation of cell cycle [GO:0045787]; positive regulation of epithelial cell proliferation [GO:0050679] cytoplasm [GO:0005737]; nucleus [GO:0005634] nucleic acid binding [GO:0003676] 0.96937 -3.4153 KRHAFSEHSSSNK 0 0 0 9.09719 0 0 0 0 0 0 0 0 0 8.95452 0 0 0 0 0 9.00756 0 0 0 0 0 11.4969 0 Q6R327 RICTR_HUMAN Rapamycin-insensitive companion of mTOR (AVO3 homolog) (hAVO3) RICTOR KIAA1999 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; cellular response to nutrient levels [GO:0031669]; cytoskeleton organization [GO:0007010]; embryo development ending in birth or egg hatching [GO:0009792]; negative regulation of apoptotic process [GO:0043066]; peptidyl-serine phosphorylation [GO:0018105]; phosphorylation [GO:0016310]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell growth [GO:0030307]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of TOR signaling [GO:0032008]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of establishment of cell polarity [GO:2000114]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of inflammatory response [GO:0050727]; regulation of peptidyl-serine phosphorylation [GO:0033135]; regulation of protein kinase B signaling [GO:0051896]; TORC2 signaling [GO:0038203] cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; TORC2 complex [GO:0031932] molecular adaptor activity [GO:0060090]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activator activity [GO:0043539]; ribosome binding [GO:0043022] 0.96877 -3.8869 ALRYLIQDSSILQKVLK 0 0 0 0 10.3726 0 8.73637 0 0 0 0 0 0 10.0294 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6RFH8 DUX4C_HUMAN "Double homeobox protein 4C (Double homeobox protein 4, centromeric) (DUX4c) (Double homeobox protein 4-like protein 9)" DUX4L9 DUX4C Homo sapiens (Human) cell population proliferation [GO:0008283]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] transcription cis-regulatory region binding [GO:0000976] 0.96958 -4.0502 ARHPGQGGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.46062 0 9.58018 0 0 0 Q6RI45 BRWD3_HUMAN Bromodomain and WD repeat-containing protein 3 BRWD3 Homo sapiens (Human) cytoskeleton organization [GO:0007010]; regulation of cell shape [GO:0008360]; regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] 0.96199 -2.4909 AYTSNKK 0 0 0 8.94723 0 0 0 0 0 0 9.11941 0 0 0 0 0 0 0 9.60027 0 0 0 0 9.49179 0 0 0 Q6RSH7 VHLL_HUMAN von Hippel-Lindau-like protein (VHL-like protein) (VLP) VHLL VLP Homo sapiens (Human) 0.92699 -1.2178 IIICNHSPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.82107 0 0 0 0 0 0 0 0 Q6S545 POTEH_HUMAN "POTE ankyrin domain family member H (ANKRD26-like family C member 3) (Prostate, ovary, testis-expressed protein on chromosome 22) (POTE-22)" POTEH A26C3 ACTBL1 POTE22 Homo sapiens (Human) 0.89045 -0.48972 DTDMNKKDK 0 0 0 0 0 0 0 0 0 0 0 9.89987 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6S5L8 SHC4_HUMAN SHC-transforming protein 4 (Rai-like protein) (RaLP) (SHC-transforming protein D) (hShcD) (Src homology 2 domain-containing-transforming protein C4) (SH2 domain protein C4) SHC4 SHCD UNQ6438/PRO21364 Homo sapiens (Human) apoptotic process [GO:0006915]; intracellular signal transduction [GO:0035556]; positive regulation of cell population proliferation [GO:0008284]; regulation of gene expression [GO:0010468]; stem cell differentiation [GO:0048863]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211] protein domain specific binding [GO:0019904]; receptor tyrosine kinase binding [GO:0030971] 0.91961 -0.90962 AIGNVHPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.67172 0 0 0 0 0 0 Q6S8J3 POTEE_HUMAN "POTE ankyrin domain family member E (ANKRD26-like family C member 1A) (Prostate, ovary, testis-expressed protein on chromosome 2) (POTE-2)" POTEE A26C1A POTE2 Homo sapiens (Human) cell motility [GO:0048870]; retina homeostasis [GO:0001895]; substantia nigra development [GO:0021762] blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; NuA4 histone acetyltransferase complex [GO:0035267]; synapse [GO:0045202] protein kinase binding [GO:0019901]; structural constituent of postsynaptic actin cytoskeleton [GO:0098973] 0.95541 -1.6016 AGFAGDDAPR 0 0 0 9.07428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6S9Z5 ZN474_HUMAN Zinc finger protein 474 (Testis-specific zinc finger protein) (TSZFP) ZNF474 Homo sapiens (Human) metal ion binding [GO:0046872] 0.95198 -1.4271 EYTNSKQQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1821 0 0 0 0 0 10.946 Q6SA08 TSSK4_HUMAN Testis-specific serine/threonine-protein kinase 4 (TSK-4) (TSSK-4) (Testis-specific kinase 4) (EC 2.7.11.1) (Serine/threonine-protein kinase 22E) TSSK4 C14orf20 STK22E TSSK5 Homo sapiens (Human) fertilization [GO:0009566]; flagellated sperm motility [GO:0030317]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine autophosphorylation [GO:1990443]; positive regulation of CREB transcription factor activity [GO:0032793]; protein phosphorylation [GO:0006468]; spermatid development [GO:0007286] acrosomal vesicle [GO:0001669]; sperm flagellum [GO:0036126] ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein-containing complex binding [GO:0044877] 0.93271 -1.2784 VLRHKYLINFYR 0 11.923 0 0 12.4011 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6SJ93 F111B_HUMAN Serine protease FAM111B (EC 3.4.21.-) (Cancer-associated nucleoprotein) FAM111B CANP Homo sapiens (Human) DNA replication [GO:0006260]; proteolysis [GO:0006508] chromatin [GO:0000785]; nucleus [GO:0005634] peptidase activity [GO:0008233] 0.91967 -0.90834 KDGETKDVEHSR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.78864 0 0 0 0 0 0 0 0 0 0 0 10.8227 0 Q6SPF0 SAMD1_HUMAN Sterile alpha motif domain-containing protein 1 (SAM domain-containing protein 1) (Atherin) SAMD1 Homo sapiens (Human) chromatin organization [GO:0006325]; foam cell differentiation [GO:0090077]; lipoprotein lipid oxidation [GO:0034439]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein homooligomerization [GO:0051260]; regulation of DNA methylation-dependent heterochromatin formation [GO:0090308] chromosome [GO:0005694]; extracellular space [GO:0005615]; nucleus [GO:0005634] chromatin binding [GO:0003682]; low-density lipoprotein particle binding [GO:0030169] 0.84821 0.17112 IYEHHIK 0 0 0 0 9.4633 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6STE5 SMRD3_HUMAN SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 (60 kDa BRG-1/Brm-associated factor subunit C) (BRG1-associated factor 60C) (BAF60C) SMARCD3 BAF60C Homo sapiens (Human) cardiac right ventricle formation [GO:0003219]; chromatin remodeling [GO:0006338]; muscle cell differentiation [GO:0042692]; nervous system development [GO:0007399]; neural retina development [GO:0003407]; nucleosome disassembly [GO:0006337]; positive regulation of cell differentiation [GO:0045597]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of T cell differentiation [GO:0045582]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of protein binding [GO:0043393]; regulation of transcription by RNA polymerase II [GO:0006357]; secondary heart field specification [GO:0003139] brahma complex [GO:0035060]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; nBAF complex [GO:0071565]; npBAF complex [GO:0071564]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SWI/SNF complex [GO:0016514] DNA-binding transcription factor binding [GO:0140297]; nuclear receptor binding [GO:0016922]; nuclear receptor coactivator activity [GO:0030374]; signaling receptor binding [GO:0005102]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription coregulator binding [GO:0001221] 0.9617 -2.5803 LLDDPSKQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.83603 0 0 0 0 0 Q6SZW1 SARM1_HUMAN NAD(+) hydrolase SARM1 (NADase SARM1) (hSARM1) (EC 3.2.2.6) (NADP(+) hydrolase SARM1) (EC 3.2.2.-) (Sterile alpha and Armadillo repeat protein) (Sterile alpha and TIR motif-containing protein 1) (Sterile alpha motif domain-containing protein 2) (MyD88-5) (SAM domain-containing protein 2) (Tir-1 homolog) (HsTIR) SARM1 KIAA0524 SAMD2 SARM Homo sapiens (Human) cell differentiation [GO:0030154]; innate immune response [GO:0045087]; NAD catabolic process [GO:0019677]; negative regulation of MyD88-independent toll-like receptor signaling pathway [GO:0034128]; nervous system development [GO:0007399]; positive regulation of neuron death [GO:1901216]; protein localization to mitochondrion [GO:0070585]; regulation of dendrite morphogenesis [GO:0048814]; regulation of neuron apoptotic process [GO:0043523]; regulation of neuron death [GO:1901214]; response to axon injury [GO:0048678]; response to glucose [GO:0009749]; signal transduction [GO:0007165] axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; microtubule [GO:0005874]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; synapse [GO:0045202] "identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; signaling adaptor activity [GO:0035591]" 0.16299 1.0054 EAEVQTWLQQIGFSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1436 0 0 0 0 0 0 0 0 10.0373 8.56102 Q6T4P5 PLPR3_HUMAN Phospholipid phosphatase-related protein type 3 (Inactive phospholipid phosphatase PLPPR3) (Lipid phosphate phosphatase-related protein type 3) (PAP-2-like protein 2) (Plasticity-related gene 2 protein) (PRG-2) PLPPR3 LPPR3 PHP2 PRG2 Homo sapiens (Human) phospholipid dephosphorylation [GO:0046839]; phospholipid metabolic process [GO:0006644]; signal transduction [GO:0007165] membrane [GO:0016020] lipid phosphatase activity [GO:0042577]; phosphatidate phosphatase activity [GO:0008195] 0.95757 -1.6635 AAGGGAK 9.88278 0 9.87374 0 0 9.12358 10.5313 10.1063 0 0 11.0626 0 0 0 0 10.8558 10.2939 11.1329 11.1467 0 8.85991 0 0 0 9.04505 8.54017 0 Q6T4R5 NHS_HUMAN Actin remodeling regulator NHS (Congenital cataracts and dental anomalies protein) (Nance-Horan syndrome protein) NHS Homo sapiens (Human) cell differentiation [GO:0030154]; lens development in camera-type eye [GO:0002088] apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; lamellipodium [GO:0030027]; nuclear body [GO:0016604] 0.9675 -2.8194 AKPTPPKR 13.6898 0 0 11.1624 0 0 0 0 0 0 0 0 0 0 0 0 0 12.0987 9.49783 0 11.3861 0 0 0 10.6342 0 12.3022 Q6TCH4 PAQR6_HUMAN Membrane progestin receptor delta (mPR delta) (Membrane progesterone P4 receptor delta) (Membrane progesterone receptor delta) (Progesterone and adipoQ receptor family member 6) (Progestin and adipoQ receptor family member 6) PAQR6 Homo sapiens (Human) plasma membrane [GO:0005886] signaling receptor activity [GO:0038023]; steroid binding [GO:0005496] 0.86831 0.068935 LPQLLQVHQVPR 0 0 0 0 0 0 9.4488 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2328 0 Q6TDU7 DNAI7_HUMAN Dynein axonemal intermediate chain 7 (Cancer susceptibility candidate gene 1 protein) (Protein CASC1) (Cilia and flagella associated protein 94) (Lung adenoma susceptibility 1-like protein) (Protein phosphatase 1 regulatory subunit 54) DNAI7 CASC1 CFAP94 LAS1 PPP1R54 Homo sapiens (Human) axonemal dynein complex [GO:0005858]; axoneme [GO:0005930]; cilium [GO:0005929] beta-tubulin binding [GO:0048487]; microtubule binding [GO:0008017] 0.96761 -3.7418 EEMERLEIQRIEK 14.3902 12.8539 13.9315 0 0 0 0 0 0 10.0176 11.2397 9.98014 0 0 0 0 12.1489 13.3666 9.98954 9.67932 9.46029 0 11.2999 0 9.93678 9.33213 9.57952 Q6TFL3 CC171_HUMAN Coiled-coil domain-containing protein 171 CCDC171 C9orf93 Homo sapiens (Human) 0.85532 0.10461 DHSNLSIPSR 0 0 0 0 0 0 0 0 0 0 0 10.1973 0 0 0 0 0 0 0 0 0 9.494 0 0 0 10.9814 0 Q6U736 OPN5_HUMAN Opsin-5 (G-protein coupled receptor 136) (G-protein coupled receptor PGR12) (Neuropsin) (Transmembrane protein 13) OPN5 GPR136 PGR12 TMEM13 Homo sapiens (Human) "cellular response to light stimulus [GO:0071482]; cellular response to UV-A [GO:0071492]; entrainment of circadian clock by photoperiod [GO:0043153]; G protein-coupled receptor signaling pathway [GO:0007186]; hyaloid vascular plexus regression [GO:1990384]; phototransduction [GO:0007602]; phototransduction, UV [GO:0007604]; visual perception [GO:0007601]" cytoplasm [GO:0005737]; plasma membrane [GO:0005886] 11-cis retinal binding [GO:0005502]; G protein-coupled photoreceptor activity [GO:0008020] 0.59177 0.46222 IHSSHVLEMK 0 0 0 0 0 0 0 0 0 0 10.3613 0 0 9.30065 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6U7Q0 ZN322_HUMAN Zinc finger protein 322 (Zinc finger protein 322A) (Zinc finger protein 388) (Zinc finger protein 489) ZNF322 ZNF322A ZNF388 ZNF489 Homo sapiens (Human) positive regulation of stem cell population maintenance [GO:1902459]; regulation of transcription by RNA polymerase II [GO:0006357] centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.88574 -0.29057 CLECMRSFTRSANLIR 0 0 11.3545 11.4048 0 0 0 0 0 0 0 0 11.0346 0 0 10.465 0 0 0 0 0 0 0 0 0 0 0 Q6U841 S4A10_HUMAN Sodium-driven chloride bicarbonate exchanger (Solute carrier family 4 member 10) SLC4A10 NBCN2 NCBE Homo sapiens (Human) bicarbonate transport [GO:0015701]; brain morphogenesis [GO:0048854]; chloride transport [GO:0006821]; locomotory exploration behavior [GO:0035641]; multicellular organism growth [GO:0035264]; post-embryonic development [GO:0009791]; proton transmembrane transport [GO:1902600]; pyramidal neuron development [GO:0021860]; regulation of intracellular pH [GO:0051453]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to light stimulus [GO:0009416]; transmembrane transport [GO:0055085]; visual perception [GO:0007601] apical dendrite [GO:0097440]; apical plasma membrane [GO:0016324]; axon terminus [GO:0043679]; basal dendrite [GO:0097441]; basolateral plasma membrane [GO:0016323]; CA3 pyramidal cell dendrite [GO:0097442]; dendrite [GO:0030425]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; somatodendritic compartment [GO:0036477]; synapse [GO:0045202] "sodium,bicarbonate:chloride antiporter activity [GO:0140892]; sodium:bicarbonate symporter activity [GO:0008510]; solute:inorganic anion antiporter activity [GO:0005452]" 0.96053 -1.9899 EVDLHFMKK 0 0 0 0 0 0 9.09587 0 0 0 0 0 0 0 0 0 0 11.3927 0 0 0 0 0 0 0 0 0 Q6U949 IG2AS_HUMAN Putative insulin-like growth factor 2 antisense gene protein (IGF2 antisense RNA 1) (IGF2 antisense gene protein 1) (PEG8/IGF2AS protein) (Putative insulin-like growth factor 2 antisense gene protein 1) (IGF2-AS1) IGF2-AS IGF2-AS1 IGF2AS Homo sapiens (Human) 0.93219 -1.2868 AESRSGAQRR 0 0 0 0 0 0 0 0 0 0 9.9173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6UB28 MAP12_HUMAN "Methionine aminopeptidase 1D, mitochondrial (MAP 1D) (MetAP 1D) (EC 3.4.11.18) (Methionyl aminopeptidase type 1D, mitochondrial) (Peptidase M 1D)" METAP1D MAP1D Homo sapiens (Human) N-terminal protein amino acid modification [GO:0031365]; peptidyl-methionine modification [GO:0018206]; protein initiator methionine removal [GO:0070084]; proteolysis [GO:0006508] mitochondrion [GO:0005739] aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]; metalloexopeptidase activity [GO:0008235] 0.84863 0.164 AAPSGVHLLVR 0 13.7303 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4973 0 0 0 0 0 0 0 0 0 0 0 Q6UB35 C1TM_HUMAN "Monofunctional C1-tetrahydrofolate synthase, mitochondrial (EC 6.3.4.3) (Formyltetrahydrofolate synthetase)" MTHFD1L FTHFSDC1 Homo sapiens (Human) 10-formyltetrahydrofolate biosynthetic process [GO:0009257]; embryonic neurocranium morphogenesis [GO:0048702]; embryonic viscerocranium morphogenesis [GO:0048703]; folic acid-containing compound metabolic process [GO:0006760]; formate metabolic process [GO:0015942]; neural tube closure [GO:0001843]; tetrahydrofolate interconversion [GO:0035999] cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; formate-tetrahydrofolate ligase activity [GO:0004329]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; protein homodimerization activity [GO:0042803] 0.87121 0.05527 GSMTMSIQWKTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1472 0 11.4201 0 0 0 9.18061 0 0 11.0289 0 Q6UB98 ANR12_HUMAN Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein) ANKRD12 ANCO2 KIAA0874 Homo sapiens (Human) cytosol [GO:0005829]; nucleoplasm [GO:0005654] 0.96936 -5.5266 DKIASYSKTPK 0 8.2556 0 0 0 0 9.30463 9.337 0 0 0 0 8.95609 9.0663 0 0 0 0 0 11.3023 0 0 10.056 0 0 0 8.72468 Q6UB99 ANR11_HUMAN Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1) ANKRD11 ANCO1 Homo sapiens (Human) face morphogenesis [GO:0060325]; odontogenesis of dentin-containing tooth [GO:0042475]; skeletal system morphogenesis [GO:0048705] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.96907 -7.4191 AEKKHAAEDK 8.66025 0 0 0 0 8.87918 0 8.58015 0 0 0 0 0 0 0 10.8126 10.5282 0 0 0 0 0 0 9.53091 12.6848 9.81463 0 Q6UDR6 SPIT4_HUMAN Kunitz-type protease inhibitor 4 SPINT4 C20orf137 Homo sapiens (Human) negative regulation of peptidase activity [GO:0010466] extracellular region [GO:0005576] serine-type endopeptidase inhibitor activity [GO:0004867] 0.96288 -2.1764 DPCKLDMNFGSCYEVHFR 0 9.00442 0 0 0 0 0 0 0 0 0 0 11.0921 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ULP2 AFTIN_HUMAN Aftiphilin AFTPH AFTH Homo sapiens (Human) intracellular transport [GO:0046907]; protein transport [GO:0015031] AP-1 adaptor complex [GO:0030121]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; trans-Golgi network membrane [GO:0032588] clathrin binding [GO:0030276] 0.9516 -1.4294 KEAWQSHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2466 11.0347 0 0 0 0 0 0 0 Q6UN15 FIP1_HUMAN Pre-mRNA 3'-end-processing factor FIP1 (hFip1) (FIP1-like 1 protein) (Factor interacting with PAP) (Rearranged in hypereosinophilia) FIP1L1 FIP1 RHE Homo sapiens (Human) mRNA processing [GO:0006397] cytosol [GO:0005829]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleoplasm [GO:0005654] RNA binding [GO:0003723] 0.88152 -0.30224 YGRAESPDLR 0 0 0 0 0 0 0 0 0 0 0 9.17073 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6UVJ0 SAS6_HUMAN Spindle assembly abnormal protein 6 homolog (HsSAS-6) SASS6 SAS6 Homo sapiens (Human) centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; positive regulation of centriole replication [GO:0046601]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of spindle assembly [GO:1905832]; regulation of mitotic spindle organization [GO:0060236] centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; deuterosome [GO:0098536]; procentriole replication complex [GO:0120099] 0.96766 -2.8143 EAFDTIQEQKVVLEENGEK 9.69213 0 0 0 0 0 0 0 0 10.2902 0 0 0 0 0 0 0 10.8176 0 0 9.98783 10.633 0 0 0 11.8976 0 Q6UVK1 CSPG4_HUMAN Chondroitin sulfate proteoglycan 4 (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan) CSPG4 MCSP Homo sapiens (Human) angiogenesis [GO:0001525]; glial cell migration [GO:0008347]; intracellular signal transduction [GO:0035556]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; ruffle assembly [GO:0097178]; substrate-dependent cell migration [GO:0006929]; tissue remodeling [GO:0048771] apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; Golgi lumen [GO:0005796]; lamellipodium membrane [GO:0031258]; lysosomal lumen [GO:0043202]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; ruffle [GO:0001726] coreceptor activity [GO:0015026]; protein kinase binding [GO:0019901] 0.92325 -1.1467 GSLLLGGLDAEASR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.486 0 0 8.76961 0 0 Q6UVM3 KCNT2_HUMAN Potassium channel subfamily T member 2 (Sequence like an intermediate conductance potassium channel subunit) (Sodium and chloride-activated ATP-sensitive potassium channel Slo2.1) KCNT2 SLICK Homo sapiens (Human) potassium ion export across plasma membrane [GO:0097623] plasma membrane [GO:0005886] ATP binding [GO:0005524]; chloride-activated potassium channel activity [GO:0070089]; intracellular sodium activated potassium channel activity [GO:0005228]; outward rectifier potassium channel activity [GO:0015271] 0.81581 0.22116 TIVNVQTLFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.95997 0 0 0 0 Q6UVY6 MOXD1_HUMAN DBH-like monooxygenase protein 1 (EC 1.14.17.-) (Monooxygenase X) MOXD1 MOX UNQ2493/PRO5780 Homo sapiens (Human) dopamine catabolic process [GO:0042420]; norepinephrine biosynthetic process [GO:0042421]; octopamine biosynthetic process [GO:0006589] endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; secretory granule membrane [GO:0030667] copper ion binding [GO:0005507]; dopamine beta-monooxygenase activity [GO:0004500] 0.95474 -1.5371 IPVFQEK 9.30083 0 0 0 0 0 0 9.19103 0 0 0 15.2934 12.9265 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6UW02 CP20A_HUMAN Cytochrome P450 20A1 (EC 1.14.-.-) CYP20A1 UNQ667/PRO1301 Homo sapiens (Human) membrane [GO:0016020] "heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]" 0.80471 0.23575 EEAWITVSK 0 0 0 0 0 0 0 0 0 0 0 10.1922 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3259 0 Q6UW49 SPESP_HUMAN Sperm equatorial segment protein 1 (SP-ESP) (Equatorial segment protein) (ESP) (Glycosylated 38 kDa sperm protein C-7/8) SPESP1 UNQ732/PRO1418 Homo sapiens (Human) acrosome reaction [GO:0007340]; fertilization [GO:0009566]; fusion of sperm to egg plasma membrane involved in single fertilization [GO:0007342]; sperm-egg recognition [GO:0035036] acrosomal vesicle [GO:0001669]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654] 0.60511 0.43832 HPESWNNDDILK 0 0 0 0 0 0 0 0 0 0 0 9.1724 0 0 0 0 0 0 0 0 0 0 9.56624 0 0 0 0 Q6UW60 PCSK4_HUMAN Proprotein convertase subtilisin/kexin type 4 (EC 3.4.21.-) (Proprotein convertase 4) (PC4) PCSK4 PC4 UNQ2757/PRO6496 Homo sapiens (Human) acrosome reaction [GO:0007340]; binding of sperm to zona pellucida [GO:0007339]; fertilization [GO:0009566]; peptide hormone processing [GO:0016486]; protein processing [GO:0016485]; reproductive process [GO:0022414]; sperm capacitation [GO:0048240] acrosomal membrane [GO:0002080]; acrosomal vesicle [GO:0001669]; membrane [GO:0016020]; trans-Golgi network [GO:0005802] serine-type endopeptidase activity [GO:0004252] 0.91824 -0.8823 LHLKKNPK 0 0 0 0 0 0 0 0 8.90488 9.24201 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6UW63 PLGT2_HUMAN Protein O-glucosyltransferase 2 (EC 2.4.1.-) (Endoplasmic reticulum resident protein 58) (ER protein 58) (ERp58) (KDEL motif-containing protein 1) (Protein O-xylosyltransferase POGLUT2) (EC 2.4.2.-) POGLUT2 EP58 KDELC1 UNQ1910/PRO4357 Homo sapiens (Human) protein O-linked glycosylation via serine [GO:0018242] cytosol [GO:0005829]; endomembrane system [GO:0012505]; endoplasmic reticulum lumen [GO:0005788]; nucleoplasm [GO:0005654] EGF-domain serine glucosyltransferase activity [GO:0140561]; EGF-domain serine xylosyltransferase activity [GO:0140562]; glucosyltransferase activity [GO:0046527]; UDP-glucosyltransferase activity [GO:0035251]; UDP-xylosyltransferase activity [GO:0035252] 0.96877 -3.0178 AGQEFAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.34753 0 0 0 0 0 0 0 0 0 Q6UW68 TM205_HUMAN Transmembrane protein 205 TMEM205 UNQ501/PRO1018 Homo sapiens (Human) membrane [GO:0016020] 0.94107 -1.3129 QLREKDPK 0 0 0 9.71339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6UWE0 LRSM1_HUMAN E3 ubiquitin-protein ligase LRSAM1 (EC 2.3.2.27) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (RING-type E3 ubiquitin transferase LRSAM1) (Tsg101-associated ligase) (hTAL) LRSAM1 TAL UNQ6496/PRO21356 Homo sapiens (Human) autophagy [GO:0006914]; negative regulation of endocytosis [GO:0045806]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of xenophagy [GO:1904417]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent endocytosis [GO:0070086]; viral budding [GO:0046755] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.8796 0.012283 LEYQMCLAK 0 0 0 0 0 0 0 0 0 0 0 11.5139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6UWF7 NXPE4_HUMAN NXPE family member 4 (Protein FAM55D) NXPE4 C11orf33 FAM55D UNQ3018/PRO9799 Homo sapiens (Human) extracellular exosome [GO:0070062] 0.91563 -0.77602 NTWNPVSCSLATVKMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.52642 0 0 0 Q6UWH4 GAK1B_HUMAN Golgi-associated kinase 1B (Expressed in nerve and epithelium during development) (Protein FAM198B) GASK1B C4orf18 ENED FAM198B AD021 UNQ2512/PRO6001 Homo sapiens (Human) Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139] 0.95389 -1.5224 IGERPWRLVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.345 0 0 0 0 0 0 0 0 Q6UWJ1 TMCO3_HUMAN Transmembrane and coiled-coil domain-containing protein 3 (Putative LAG1-interacting protein) TMCO3 C13orf11 UNQ2419/PRO4976 Homo sapiens (Human) membrane [GO:0016020] potassium:proton antiporter activity [GO:0015386] 0.72687 0.34084 HQVEALKNMQHQNQSLSMLDEILEDVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2386 0 0 0 0 0 0 0 0 0 0 Q6UWL2 SUSD1_HUMAN Sushi domain-containing protein 1 SUSD1 UNQ2438/PRO4999 Homo sapiens (Human) membrane [GO:0016020] calcium ion binding [GO:0005509] 0.94734 -1.3535 EGKKICICNYGFVGNGR 0 0 10.2116 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6UWM7 LCTL_HUMAN Lactase-like protein (Klotho/lactase-phlorizin hydrolase-related protein) LCTL KLPH UNQ3022/PRO9820 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; response to stimulus [GO:0050896]; visual perception [GO:0007601] endoplasmic reticulum membrane [GO:0005789] beta-glucosidase activity [GO:0008422] 0.95978 -1.9377 IQYLKGYINEMLK 0 0 0 0 0 0 0 8.99616 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.05393 Q6UWN5 LYPD5_HUMAN Ly6/PLAUR domain-containing protein 5 LYPD5 UNQ1908/PRO4356 Homo sapiens (Human) extracellular region [GO:0005576]; plasma membrane [GO:0005886] 0.84304 0.15187 MAMGVPR 0 0 0 0 0 0 0 0 10.2713 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6UWP2 DHR11_HUMAN Dehydrogenase/reductase SDR family member 11 (17-beta-hydroxysteroid dehydrogenase) (3-beta-hydroxysteroid 3-dehydrogenase) (EC 1.1.1.270) (Estradiol 17-beta-dehydrogenase) (EC 1.1.1.62) (Short-chain dehydrogenase/reductase family 24C member 1) DHRS11 SDR24C1 UNQ836/PRO1774 Homo sapiens (Human) estrogen biosynthetic process [GO:0006703]; steroid biosynthetic process [GO:0006694] extracellular region [GO:0005576] 17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; 17-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0072582]; 17-beta-ketosteroid reductase activity [GO:0072555]; 3-keto sterol reductase activity [GO:0000253]; cycloeucalenone reductase activity [GO:0102176]; estradiol 17-beta-dehydrogenase [NAD(P)] activity [GO:0004303]; nucleotide binding [GO:0000166] 0.89904 -0.66411 ALVQQGLK 0 0 0 0 0 0 0 0 0 0 14.5702 0 0 0 0 0 0 0 0 0 0 0 0 0 9.84068 9.72446 9.72635 Q6UWP7 LCLT1_HUMAN Lysocardiolipin acyltransferase 1 (EC 2.3.1.-) (1-acylglycerol-3-phosphate O-acyltransferase 8) (1-AGP acyltransferase 8) (1-AGPAT 8) (EC 2.3.1.51) (Acyl-CoA:lysocardiolipin acyltransferase 1) LCLAT1 AGPAT8 ALCAT1 LYCAT UNQ1849/PRO3579 Homo sapiens (Human) cardiolipin acyl-chain remodeling [GO:0035965]; CDP-diacylglycerol biosynthetic process [GO:0016024]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylinositol acyl-chain remodeling [GO:0036149] cytosol [GO:0005829]; endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] 1-acylglycerol-3-phosphate O-acyltransferase activity [GO:0003841]; acyltransferase activity [GO:0016746]; O-acyltransferase activity [GO:0008374] 0.96991 -3.2576 EERLRSFYQGEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.97977 0 0 Q6UWP8 SBSN_HUMAN Suprabasin SBSN UNQ698/PRO1343 Homo sapiens (Human) extracellular exosome [GO:0070062] 0.95125 -1.4351 ALDGINSGITHAGR 0 0 0 0 0 0 0 12.5639 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6UWR7 ENPP6_HUMAN Glycerophosphocholine cholinephosphodiesterase ENPP6 (GPC-Cpde) (EC 3.1.4.-) (EC 3.1.4.38) (Choline-specific glycerophosphodiester phosphodiesterase) (Ectonucleotide pyrophosphatase/phosphodiesterase family member 6) (E-NPP 6) (NPP-6) ENPP6 UNQ1889/PRO4334 Homo sapiens (Human) choline metabolic process [GO:0019695]; glycerophospholipid catabolic process [GO:0046475]; lipid metabolic process [GO:0006629] extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; plasma membrane [GO:0005886] glycerophosphocholine cholinephosphodiesterase activity [GO:0047390]; glycerophosphodiester phosphodiesterase activity [GO:0008889]; metal ion binding [GO:0046872]; phosphoric diester hydrolase activity [GO:0008081] 0.81549 0.22109 ADLAAIYHER 0 0 0 8.54512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.227 0 0 Q6UWU2 GLB1L_HUMAN Beta-galactosidase-1-like protein (EC 3.2.1.-) GLB1L UNQ229/PRO262 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975] extracellular region [GO:0005576]; lysosome [GO:0005764]; vacuole [GO:0005773] beta-galactosidase activity [GO:0004565] 0.74947 0.31303 LDILVENMGR 0 8.84837 0 0 0 0 0 9.22598 0 0 0 0 11.5507 11.7187 0 13.7281 0 0 0 0 0 0 0 0 0 0 0 Q6UWX4 HIPL2_HUMAN HHIP-like protein 2 HHIPL2 HHIP3 KIAA1822L UNQ841/PRO1779 Homo sapiens (Human) extracellular region [GO:0005576] 0.89823 -0.56805 LASPTSSK 0 0 12.0755 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6UWZ7 ABRX1_HUMAN BRCA1-A complex subunit Abraxas 1 (Coiled-coil domain-containing protein 98) (Protein FAM175A) ABRAXAS1 ABRA1 CCDC98 FAM175A UNQ496/PRO1013 Homo sapiens (Human) attachment of spindle microtubules to kinetochore [GO:0008608]; chromatin organization [GO:0006325]; double-strand break repair [GO:0006302]; histone H2A K63-linked deubiquitination [GO:0070537]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; mitotic G2/M transition checkpoint [GO:0044818]; mitotic spindle assembly [GO:0090307]; positive regulation of DNA repair [GO:0045739]; protein K63-linked deubiquitination [GO:0070536]; regulation of DNA repair [GO:0006282]; response to ionizing radiation [GO:0010212] BRCA1-A complex [GO:0070531]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] microtubule binding [GO:0008017]; polyubiquitin modification-dependent protein binding [GO:0031593] 0.9601 -1.9419 ADTGSSNQDK 0 0 0 0 0 0 0 0 0 0 0 0 9.86211 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6UX01 LMBRL_HUMAN Protein LMBR1L (Limb region 1 protein homolog-like) (Lipocalin-1-interacting membrane receptor) (LIMR) LMBR1L KIAA1174 LIMR UNQ458/PRO783 Homo sapiens (Human) hematopoietic stem cell differentiation [GO:0060218]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; receptor-mediated endocytosis [GO:0006898]; signal transduction [GO:0007165]; T cell apoptotic process [GO:0070231]; T cell differentiation [GO:0030217]; T cell proliferation [GO:0042098]; Wnt signaling pathway [GO:0016055] endoplasmic reticulum membrane [GO:0005789]; plasma membrane [GO:0005886] transmembrane signaling receptor activity [GO:0004888] 0.78555 0.25203 EAPDYEVLSVR 9.34921 9.29476 8.94477 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6UX06 OLFM4_HUMAN Olfactomedin-4 (OLM4) (Antiapoptotic protein GW112) (G-CSF-stimulated clone 1 protein) (hGC-1) (hOLfD) OLFM4 GW112 UNQ362/PRO698 Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; signal transduction [GO:0007165] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intercellular bridge [GO:0045171]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724] cadherin binding [GO:0045296]; structural molecule activity [GO:0005198] 0.96306 -2.442 LKECEASK 0 0 0 0 0 0 0 0 0 0 0 9.73234 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6UX07 DHR13_HUMAN Dehydrogenase/reductase SDR family member 13 (EC 1.1.-.-) (Short chain dehydrogenase/reductase family 7C member 5) (Protein SDR7C5) DHRS13 SDR7C5 UNQ419/PRO853 Homo sapiens (Human) extracellular region [GO:0005576]; membrane [GO:0016020] oxidoreductase activity [GO:0016491] 0.95497 -1.5192 GEAAAFDLR 0 0 0 0 0 9.17255 0 0 0 0 0 0 0 0 0 0 0 0 0 9.33588 0 0 0 0 0 0 0 Q6UX41 BTNL8_HUMAN Butyrophilin-like protein 8 BTNL8 UNQ702/PRO1347 Homo sapiens (Human) adaptive immune response [GO:0002250]; regulation of cytokine production [GO:0001817]; T cell receptor signaling pathway [GO:0050852] external side of plasma membrane [GO:0009897]; plasma membrane [GO:0005886] signaling receptor binding [GO:0005102] 0.87131 0.048619 LNGEHLYFTLNPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.212 0 0 0 0 0 0 0 0 0 0 0 0 Q6UX65 DRAM2_HUMAN DNA damage-regulated autophagy modulator protein 2 (Transmembrane protein 77) DRAM2 TMEM77 PSEC0031 UNQ154/PRO180 Homo sapiens (Human) apoptotic process [GO:0006915]; autophagy [GO:0006914]; photoreceptor cell maintenance [GO:0045494]; regulation of autophagy [GO:0010506]; visual perception [GO:0007601] apical plasma membrane [GO:0016324]; cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; photoreceptor inner segment [GO:0001917] 0.94392 -1.336 TRLLSRDI 0 0 0 0 0 0 0 0 10.9039 0 0 10.4389 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6UX71 PXDC2_HUMAN Plexin domain-containing protein 2 (Tumor endothelial marker 7-related protein) PLXDC2 TEM7R UNQ2514/PRO6003 Homo sapiens (Human) membrane [GO:0016020] 0.9628 -2.1781 NLDFLKAVDTNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.58018 0 0 0 Q6UX73 CP089_HUMAN UPF0764 protein C16orf89 C16orf89 UNQ904/PRO1925 Homo sapiens (Human) cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020] protein homodimerization activity [GO:0042803] 0.87387 0.023424 AEAIGYAYPTR 0 0 0 0 0 0 0 0 0 0 0 9.13006 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6UXB2 CXL17_HUMAN C-X-C motif chemokine 17 (6-Cys CXCL17) (Dendritic cell and monocyte chemokine-like protein) (DMC) (VEGF coregulated chemokine 1) [Cleaved into: 4-Cys CXCL17] CXCL17 VCC1 UNQ473/PRO842 Homo sapiens (Human) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; macrophage chemotaxis [GO:0048246]; negative regulation of inflammatory response [GO:0050728]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of vascular endothelial growth factor production [GO:0010575] extracellular space [GO:0005615] 0.96955 -5.0817 DWFLRAPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.07095 0 0 0 0 0 0 0 Q6UXB4 CLC4G_HUMAN C-type lectin domain family 4 member G (Liver and lymph node sinusoidal endothelial cell C-type lectin) (LSECtin) CLEC4G UNQ431/PRO792 Homo sapiens (Human) alpha-beta T cell proliferation [GO:0046633]; immature T cell proliferation in thymus [GO:0033080]; immune response [GO:0006955]; negative regulation of alpha-beta T cell proliferation [GO:0046642]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; negative regulation of T cell mediated immunity [GO:0002710]; positive regulation of viral life cycle [GO:1903902]; T cell mediated immunity [GO:0002456]; viral entry into host cell [GO:0046718] external side of plasma membrane [GO:0009897]; plasma membrane [GO:0005886] carbohydrate binding [GO:0030246]; carbohydrate derivative binding [GO:0097367]; fructose binding [GO:0070061]; glycosylated region protein binding [GO:0140081]; mannose binding [GO:0005537]; polysaccharide binding [GO:0030247]; virus coreceptor activity [GO:0120274]; virus receptor activity [GO:0001618] 0.94025 -1.3301 VTQGLAEAGRGREDVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6456 0 Q6UXB8 PI16_HUMAN Peptidase inhibitor 16 (PI-16) (Cysteine-rich secretory protein 9) (CRISP-9) (PSP94-binding protein) (CD antigen CD364) PI16 CRISP9 PSPBP PSEC0164 UNQ289/PRO328 Homo sapiens (Human) negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; negative regulation of peptidase activity [GO:0010466] extracellular space [GO:0005615] peptidase inhibitor activity [GO:0030414] 0.96488 -2.2824 ALPAVETQAPTSLATK 0 0 0 0 0 0 0 0 0 0 0 0 8.21096 8.19972 8.43075 0 0 0 0 0 0 8.59141 0 0 0 0 0 Q6UXC1 AEGP_HUMAN Apical endosomal glycoprotein (MAM domain-containing protein 4) MAMDC4 AEGP UNQ3001/PRO9742 Homo sapiens (Human) protein transport [GO:0015031] Golgi apparatus [GO:0005794]; membrane [GO:0016020] 0.9561 -1.5436 LGSMDVQAER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.50331 0 0 0 0 0 0 0 0 0 0 0 0 Q6UXG2 ELAP1_HUMAN Endosome/lysosome-associated apoptosis and autophagy regulator 1 (Estrogen-induced gene 121 protein) ELAPOR1 EIG121 KIAA1324 UNQ2426/PRO4985 Homo sapiens (Human) autophagosome assembly [GO:0000045]; cellular response to starvation [GO:0009267]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of vacuole organization [GO:0044090] endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886] RNA binding [GO:0003723] 0.86982 0.052373 QGSSFCKLCPANSYSNK 0 0 0 0 0 0 0 10.1485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6UXH8 CCBE1_HUMAN Collagen and calcium-binding EGF domain-containing protein 1 (Full of fluid protein homolog) CCBE1 KIAA1983 UNQ1921/PRO4395 Homo sapiens (Human) lung development [GO:0030324]; lymphangiogenesis [GO:0001946]; lymphatic endothelial cell migration [GO:1904977]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of lymphangiogenesis [GO:1901492]; positive regulation of protein processing [GO:0010954]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; respiratory system process [GO:0003016]; sprouting angiogenesis [GO:0002040]; venous blood vessel morphogenesis [GO:0048845] collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615] calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; protease binding [GO:0002020] 0.8711 0.048518 IALLPNNAADLGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.79918 0 Q6UXH9 PAMR1_HUMAN Inactive serine protease PAMR1 (Peptidase domain-containing protein associated with muscle regeneration 1) (Regeneration-associated muscle protease homolog) PAMR1 RAMP FP938 UNQ699/PRO1344 Homo sapiens (Human) extracellular region [GO:0005576] calcium ion binding [GO:0005509] 0.9316 -1.2557 ISTRVQPICLAASR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.5281 0 0 0 0 0 0 0 0 Q6UXI9 NPNT_HUMAN Nephronectin (Preosteoblast EGF-like repeat protein with MAM domain) (Protein EGFL6-like) NPNT EGFL6L POEM UNQ295/PRO334 Homo sapiens (Human) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion mediated by integrin [GO:0033631]; cell-matrix adhesion [GO:0007160]; cellular response to tumor necrosis factor [GO:0071356]; establishment of protein localization [GO:0045184]; extracellular matrix organization [GO:0030198]; pilomotor reflex [GO:0097195]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; smooth muscle cell differentiation [GO:0051145]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ureteric bud development [GO:0001657] basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; smooth muscle contractile fiber [GO:0030485] calcium ion binding [GO:0005509]; integrin binding [GO:0005178] 0.89798 -0.55767 CKCHPGYAGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2066 0 0 0 0 0 0 0 0 0 0 Q6UXL0 I20RB_HUMAN Interleukin-20 receptor subunit beta (IL-20 receptor subunit beta) (IL-20R-beta) (IL-20RB) (Fibronectin type III domain containing 6) (FNDC6) (IL-20R2) IL20RB DIRS1 UNQ557/PRO1114 Homo sapiens (Human) homeostasis of number of cells within a tissue [GO:0048873]; immune response-inhibiting signal transduction [GO:0002765]; inflammatory response to antigenic stimulus [GO:0002437]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of type II interferon production [GO:0032689]; negative regulation of type IV hypersensitivity [GO:0001808]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-4 production [GO:0032753]; T cell homeostasis [GO:0043029]; T cell proliferation [GO:0042098] plasma membrane [GO:0005886] interleukin-20 binding [GO:0042015] 0.91003 -0.74738 REPGAEEHVKMVR 0 0 8.70888 0 0 0 0 0 0 0 11.7669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6UXM1 LRIG3_HUMAN Leucine-rich repeats and immunoglobulin-like domains protein 3 (LIG-3) LRIG3 LIG3 UNQ287/PRO326/PRO335 Homo sapiens (Human) otolith morphogenesis [GO:0032474] cytoplasmic vesicle membrane [GO:0030659]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] 0.38702 0.71265 KLQQLHLNTSSLLCDCQLK 0 9.68384 0 11.8042 0 0 0 0 12.289 0 0 0 0 0 0 13.3784 0 0 0 0 0 0 0 0 0 0 0 Q6UXN9 WDR82_HUMAN WD repeat-containing protein 82 WDR82 SWD2 TMEM113 WDR82A UNQ9342/PRO34047 Homo sapiens (Human) "DNA-templated transcription termination [GO:0006353]; histone H3-K4 methylation [GO:0051568]; lncRNA catabolic process [GO:0110064]; negative regulation of DNA-templated transcription, elongation [GO:0032785]; negative regulation of lncRNA transcription [GO:0140744]; nuclear RNA surveillance [GO:0071027]" chromatin [GO:0000785]; histone methyltransferase complex [GO:0035097]; nucleolus [GO:0005730]; PTW/PP1 phosphatase complex [GO:0072357]; Set1C/COMPASS complex [GO:0048188] chromatin binding [GO:0003682] 0.89891 -0.57587 GVVMHTFGGYANSK 0 0 0 0 0 9.40154 0 0 0 0 0 0 0 0 0 10.1195 0 0 0 0 0 0 0 0 0 0 0 Q6UXR4 SPA13_HUMAN Putative serpin A13 SERPINA13P SERPINA13 UNQ6121/PRO20043 Homo sapiens (Human) negative regulation of endopeptidase activity [GO:0010951] extracellular space [GO:0005615] serine-type endopeptidase inhibitor activity [GO:0004867] 0.89847 -0.64453 FSGLGAR 9.53045 0 9.27195 0 0 0 0 0 0 0 8.79993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6UXT8 ALKL1_HUMAN ALK and LTK ligand 1 (Augmentor beta) (AUG-beta) ALKAL1 FAM150A UNQ9433/PRO34745 Homo sapiens (Human) positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of ERK5 cascade [GO:0070378]; positive regulation of neuron projection development [GO:0010976]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] extracellular space [GO:0005615]; plasma membrane [GO:0005886] cytokine activity [GO:0005125]; receptor signaling protein tyrosine kinase activator activity [GO:0030298]; receptor tyrosine kinase binding [GO:0030971]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297] 0.91545 -0.80501 HFTGPVTFSPECSKHFHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.946 0 0 0 0 0 0 0 0 0 0 0 Q6UXU0 YS002_HUMAN Putative uncharacterized protein UNQ9165/PRO28630 UNQ9165/PRO28630 Homo sapiens (Human) extracellular region [GO:0005576] 0.95222 -1.4535 SHMGKLKEPQPQDHKPGLGAS 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1165 0 0 0 0 0 Q6UXU4 GSG1L_HUMAN Germ cell-specific gene 1-like protein (GSG1-like protein) GSG1L UNQ5831/PRO19651 Homo sapiens (Human) regulation of AMPA receptor activity [GO:2000311]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149] glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; Schaffer collateral - CA1 synapse [GO:0098685] 0.96152 -2.6038 TVIEFRHK 11.7829 0 0 0 0 0 0 0 0 0 0 9.41939 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6UXV4 MIC27_HUMAN MICOS complex subunit MIC27 (Apolipoprotein O-like) (Protein FAM121A) APOOL CXorf33 FAM121A MIC27 UNQ8193/PRO23204 Homo sapiens (Human) cristae formation [GO:0042407]; inner mitochondrial membrane organization [GO:0007007] extracellular region [GO:0005576]; MIB complex [GO:0140275]; MICOS complex [GO:0061617]; mitochondrial crista junction [GO:0044284]; mitochondrion [GO:0005739]; platelet alpha granule lumen [GO:0031093]; SAM complex [GO:0001401] 0.95386 -1.5243 NPPRDFLPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.17615 0 0 0 0 0 0 0 0 0 0 Q6UXX9 RSPO2_HUMAN R-spondin-2 (Roof plate-specific spondin-2) (hRspo2) RSPO2 UNQ9384/PRO34209 Homo sapiens (Human) bone mineralization [GO:0030282]; canonical Wnt signaling pathway [GO:0060070]; dopaminergic neuron differentiation [GO:0071542]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; limb development [GO:0060173]; lung growth [GO:0060437]; negative regulation of odontogenesis of dentin-containing tooth [GO:0042489]; osteoblast differentiation [GO:0001649]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Wnt signaling pathway [GO:0030177]; trachea cartilage morphogenesis [GO:0060535] cell surface [GO:0009986]; extracellular region [GO:0005576] heparin binding [GO:0008201]; signaling receptor binding [GO:0005102] 0.96254 -2.4477 DTILCPTIAESRR 0 9.76411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5227 0 0 0 0 0 0 0 Q6UXY8 TMC5_HUMAN Transmembrane channel-like protein 5 TMC5 UNQ8238/PRO33604 Homo sapiens (Human) extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] mechanosensitive monoatomic ion channel activity [GO:0008381] 0.93231 -1.2634 LIFCWDFTVTHEKAVKLK 0 0 9.69799 9.67476 0 9.36599 0 0 0 10.0403 0 0 0 0 0 0 0 12.1827 0 0 0 0 0 0 0 0 11.4744 Q6UXZ0 TMIG1_HUMAN Transmembrane and immunoglobulin domain-containing protein 1 TMIGD1 TMIGD UNQ9372/PRO34164 Homo sapiens (Human) brush border assembly [GO:1904970]; cell aggregation [GO:0098743]; cell migration [GO:0016477]; cell-cell junction organization [GO:0045216]; cellular response to hydroperoxide [GO:0071447]; intestinal epithelial cell maturation [GO:0060574]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epithelial cell proliferation [GO:0050680]; protein localization [GO:0008104]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127]; regulation of membrane permeability [GO:0090559]; response to nutrient [GO:0007584] cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; plasma membrane [GO:0005886] cell-cell adhesion mediator activity [GO:0098632]; protein homodimerization activity [GO:0042803] 0.81334 0.22149 EMTSSVLTVNGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.94845 0 0 0 0 0 0 0 0 0 0 0 0 Q6UXZ3 CLM5_HUMAN CMRF35-like molecule 5 (CLM-5) (CD300 antigen-like family member D) (CMRF35-A4) (CD antigen CD300d) CD300LD CD300D CMRF35A4 UNQ9218/PRO28686 Homo sapiens (Human) immune system process [GO:0002376] plasma membrane [GO:0005886] transmembrane signaling receptor activity [GO:0004888] 0.9558 -1.5439 KNRVSIR 0 0 0 0 0 0 0 0 0 0 0 8.65367 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6UY11 DLK2_HUMAN Protein delta homolog 2 (DLK-2) (Epidermal growth factor-like protein 9) (EGF-like protein 9) DLK2 EGFL9 UNQ2903/PRO28633 Homo sapiens (Human) negative regulation of Notch signaling pathway [GO:0045746]; regulation of fat cell differentiation [GO:0045598] membrane [GO:0016020] calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; Notch binding [GO:0005112] 0.95013 -1.3838 DLPPEPGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.58609 0 0 0 0 0 0 0 0 0 Q6UY14 ATL4_HUMAN ADAMTS-like protein 4 (ADAMTSL-4) (Thrombospondin repeat-containing protein 1) ADAMTSL4 TSRC1 PP1396 UNQ2803/PRO34012 Homo sapiens (Human) apoptotic process [GO:0006915]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; pigment cell development [GO:0070285]; positive regulation of apoptotic process [GO:0043065] collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; interstitial matrix [GO:0005614] identical protein binding [GO:0042802]; protease binding [GO:0002020] 0.78502 0.25656 TPLGSPAAYWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0771 0 0 0 0 0 0 Q6UYE1 LEU7_HUMAN Leukemia-associated protein 7 (Deleted in lymphocytic leukemia 7) DLEU7 LEU7 Homo sapiens (Human) 0.56365 0.51393 DLNAAHQCLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.8661 0 0 0 Q6V0I7 FAT4_HUMAN Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) FAT4 CDHF14 FATJ Nbla00548 Homo sapiens (Human) cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.95152 -1.4305 AGSFVGKVSAVDKDFGPNGEVR 0 0 0 0 0 0 0 0 0 12.7069 0 13.4387 8.17901 10.1677 9.25611 10.6908 9.98911 9.92649 0 0 0 9.49025 9.70409 0 0 0 0 Q6V0L0 CP26C_HUMAN Cytochrome P450 26C1 (CYP26C1) (EC 1.14.14.1) CYP26C1 Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; central nervous system development [GO:0007417]; negative regulation of retinoic acid receptor signaling pathway [GO:0048387]; neural crest cell development [GO:0014032]; organelle fusion [GO:0048284]; retinoic acid catabolic process [GO:0034653]; sterol metabolic process [GO:0016125]; vitamin metabolic process [GO:0006766] endoplasmic reticulum membrane [GO:0005789] heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; retinoic acid 4-hydroxylase activity [GO:0008401]; retinoic acid binding [GO:0001972] 0.95111 -1.4332 FGAAREDSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.90064 0 0 0 0 0 Q6V1P9 PCD23_HUMAN Protocadherin-23 (Cadherin-27) (Cadherin-like protein CDHJ) (Cadherin-like protein VR8) (Protein dachsous homolog 2) (Protocadherin PCDHJ) DCHS2 CDH27 CDHJ PCDH23 PCDHJ Homo sapiens (Human) condensed mesenchymal cell proliferation [GO:0072137]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nephron development [GO:0072006] plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.9519 -1.3944 EEAAAHR 0 0 9.31179 0 0 0 14.1154 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.4108 Q6V1X1 DPP8_HUMAN Dipeptidyl peptidase 8 (DP8) (EC 3.4.14.5) (Dipeptidyl peptidase IV-related protein 1) (DPRP-1) (Dipeptidyl peptidase VIII) (DPP VIII) (Prolyl dipeptidase DPP8) DPP8 DPRP1 MSTP097 MSTP135 MSTP141 Homo sapiens (Human) apoptotic process [GO:0006915]; immune response [GO:0006955]; negative regulation of programmed cell death [GO:0043069]; proteolysis [GO:0006508] cytoplasm [GO:0005737]; cytosol [GO:0005829] aminopeptidase activity [GO:0004177]; dipeptidyl-peptidase activity [GO:0008239]; serine-type peptidase activity [GO:0008236] 0.88307 -0.10532 AGWTPEGK 9.35865 0 0 0 0 0 0 0 0 0 0 9.57043 0 0 0 0 0 8.5472 0 0 0 0 0 0 0 0 0 Q6V702 CF299_HUMAN Cilia- and flagella-associated protein 299 CFAP299 C4orf22 Homo sapiens (Human) cytoplasm [GO:0005737]; nucleus [GO:0005634] 0.90067 -0.6929 AQPGDNSTR 0 0 0 0 0 0 12.2289 0 0 0 9.00324 0 0 11.8655 11.899 0 11.5465 0 0 0 0 0 0 0 0 0 0 Q6VAB6 KSR2_HUMAN Kinase suppressor of Ras 2 (hKSR2) (EC 2.7.11.1) KSR2 Homo sapiens (Human) calcium-mediated signaling [GO:0019722]; positive regulation of cold-induced thermogenesis [GO:0120162]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265] cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96984 -3.2719 EIRTLESK 0 0 0 0 0 0 0 11.4148 0 0 0 0 0 0 0 0 11.1967 0 0 0 0 0 0 0 0 0 0 Q6VMQ6 MCAF1_HUMAN Activating transcription factor 7-interacting protein 1 (ATF-interacting protein) (ATF-IP) (ATF7-interacting protein) (ATFa-associated modulator) (hAM) (MBD1-containing chromatin-associated factor 1) (P621) ATF7IP MCAF MCAF1 Homo sapiens (Human) DNA methylation [GO:0006306]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309]; positive regulation of DNA-templated transcription [GO:0045893]; protein stabilization [GO:0050821]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein stability [GO:0031647]; regulation of RNA polymerase II transcription preinitiation complex assembly [GO:0045898] cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] ATP hydrolysis activity [GO:0016887]; transcription coregulator activity [GO:0003712]; transcription corepressor activity [GO:0003714] 0.95035 -1.4091 DSLEEPQKK 0 0 0 0 8.87295 0 0 0 0 0 10.4213 9.18926 0 0 0 0 0 0 0 0 0 9.67234 0 0 0 0 0 Q6VN20 RBP10_HUMAN Ran-binding protein 10 (RanBP10) RANBP10 KIAA1464 Homo sapiens (Human) cytoskeleton organization [GO:0007010] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151] 0.90558 -0.72829 CRQFVEMVNGTDSEVR 9.43833 0 0 0 0 0 0 8.77142 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6W2J9 BCOR_HUMAN BCL-6 corepressor (BCoR) BCOR KIAA1575 Homo sapiens (Human) blastocyst hatching [GO:0001835]; chromatin remodeling [GO:0006338]; heart development [GO:0007507]; negative regulation of bone mineralization [GO:0030502]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of tooth mineralization [GO:0070171]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; roof of mouth development [GO:0060021]; specification of axis polarity [GO:0065001] BCOR complex [GO:0140261]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA-binding transcription factor binding [GO:0140297]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; transcription cis-regulatory region binding [GO:0000976]; transcription corepressor activity [GO:0003714] 0.83011 0.20628 DGSSPPLLEK 0 12.7084 0 0 0 0 0 0 0 0 11.12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6WCQ1 MPRIP_HUMAN Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip) MPRIP KIAA0864 MRIP RHOIP3 Homo sapiens (Human) actin cytoskeleton [GO:0015629]; cytosol [GO:0005829]; focal adhesion [GO:0005925] actin filament binding [GO:0051015]; cadherin binding [GO:0045296] 0.85763 0.10086 EGYVLQATCERGFAAMEETHQK 0 13.3945 0 8.67062 0 0 0 9.5636 0 0 0 0 0 0 9.43565 0 0 0 0 9.82564 0 0 0 0 0 0 0 Q6WKZ4 RFIP1_HUMAN Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein) RAB11FIP1 RCP Homo sapiens (Human) negative regulation of adiponectin secretion [GO:0070164]; protein transport [GO:0015031]; regulated exocytosis [GO:0045055] cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; phagocytic vesicle membrane [GO:0030670]; recycling endosome [GO:0055037] small GTPase binding [GO:0031267] 0.89815 -0.55705 ATAEGSAGR 10.0445 0 10.0498 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.84119 9.87575 0 0 0 0 0 0 Q6WRI0 IGS10_HUMAN Immunoglobulin superfamily member 10 (IgSF10) (Calvaria mechanical force protein 608) (CMF608) IGSF10 CMF608 Homo sapiens (Human) cell differentiation [GO:0030154]; ossification [GO:0001503]; regulation of neuron migration [GO:2001222] extracellular region [GO:0005576] 0.96367 -2.4379 ENRRHFPPSAR 0 0 0 0 0 0 0 10.5911 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5599 Q6WRX3 ZY11A_HUMAN Protein zyg-11 homolog A ZYG11A ZYG11 Homo sapiens (Human) Cul2-RING ubiquitin ligase complex [GO:0031462] 0.85039 0.15967 ISTAAFIKAFCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.80642 0 0 0 0 0 0 0 0 0 0 Q6X9E4 FBW12_HUMAN F-box/WD repeat-containing protein 12 (F-box and WD-40 domain-containing protein 12) (F-box only protein 35) FBXW12 FBW12 FBXO12 FBXO35 Homo sapiens (Human) cytosol [GO:0005829] 0.75252 0.31086 LTVDEQEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3642 0 0 Q6XE24 RBMS3_HUMAN "RNA-binding motif, single-stranded-interacting protein 3" RBMS3 Homo sapiens (Human) defense response to tumor cell [GO:0002357]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of gene expression [GO:0010629]; positive regulation of gene expression [GO:0010628] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266] 0.95521 -1.6038 AILDKNTNQCK 0 0 0 0 0 0 0 0 0 0 0 0 9.25333 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6XPR3 RPTN_HUMAN Repetin RPTN Homo sapiens (Human) cornified envelope [GO:0001533]; cytosol [GO:0005829]; extracellular region [GO:0005576] calcium ion binding [GO:0005509]; transition metal ion binding [GO:0046914] 0.96817 -2.7598 FPGNTGRQHR 0 0 0 0 0 0 0 0 0 9.5144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6XPS3 TPTE2_HUMAN "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (Lipid phosphatase TPIP) (TPTE and PTEN homologous inositol lipid phosphatase)" TPTE2 TPIP Homo sapiens (Human) dephosphorylation [GO:0016311]; phosphatidylinositol biosynthetic process [GO:0006661] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139] "phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [GO:0051800]" 0.91473 -0.81354 IFHLLHQK 0 0 0 0 0 0 0 11.4106 11.5608 0 0 0 0 0 0 10.6329 0 10.5284 9.79237 0 10.9009 0 0 0 0 0 0 Q6XQN6 PNCB_HUMAN Nicotinate phosphoribosyltransferase (NAPRTase) (EC 6.3.4.21) (FHA-HIT-interacting protein) (Nicotinate phosphoribosyltransferase domain-containing protein 1) NAPRT FHIP NAPRT1 Homo sapiens (Human) NAD salvage [GO:0034355]; response to oxidative stress [GO:0006979] azurophil granule lumen [GO:0035578]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576] metal ion binding [GO:0046872]; nicotinate phosphoribosyltransferase activity [GO:0004516]; transferase activity [GO:0016740] 0.96891 -4.843 FLRAFRLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.44452 0 0 10.1784 0 0 0 0 0 0 0 0 Q6XR72 ZNT10_HUMAN Calcium/manganese antiporter SLC30A10 (Solute carrier family 30 member 10) (Zinc transporter 10) (ZnT-10) SLC30A10 ZNT10 ZNT8 Homo sapiens (Human) cellular response to angiotensin [GO:1904385]; detoxification of zinc ion [GO:0010312]; epidermal growth factor receptor signaling pathway [GO:0007173]; intracellular manganese ion homeostasis [GO:0030026]; intracellular zinc ion homeostasis [GO:0006882]; manganese ion export across plasma membrane [GO:0140048]; manganese ion transport [GO:0006828]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; zinc ion import into organelle [GO:0062111]; zinc ion transmembrane transport [GO:0071577] early endosome [GO:0005769]; early endosome membrane [GO:0031901]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038] calcium:manganese antiporter activity [GO:0140983]; manganese ion transmembrane transporter activity [GO:0005384]; zinc ion transmembrane transporter activity [GO:0005385] 0.92265 -1.0852 GVNMEELMSK 0 0 0 0 0 0 0 0 0 0 0 0 0 8.81944 0 0 0 0 0 0 0 0 8.92784 0 0 0 0 Q6XUX3 DUSTY_HUMAN Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase) (Receptor-interacting serine/threonine-protein kinase 5) (Sugen kinase 496) (SgK496) DSTYK KIAA0472 RIP5 RIPK5 SGK496 HDCMD38P Homo sapiens (Human) cellular response to fibroblast growth factor stimulus [GO:0044344]; negative regulation of apoptotic process [GO:0043066]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743]; positive regulation of kinase activity [GO:0033674]; protein phosphorylation [GO:0006468] anchoring junction [GO:0070161]; apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cytoplasm [GO:0005737] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein tyrosine kinase activity [GO:0004713] 0.96744 -2.852 AQSMLVEQSEK 9.86949 0 0 0 0 0 0 0 0 0 9.80753 9.27738 0 0 0 0 0 10.312 0 0 0 0 0 0 0 0 0 Q6XYB7 LBX2_HUMAN Transcription factor LBX2 (Ladybird homeobox 2) (Ladybird homeobox protein homolog 2) LBX2 LP3727 Homo sapiens (Human) muscle cell differentiation [GO:0042692]; positive regulation of convergent extension involved in gastrulation [GO:1904105]; positive regulation of non-canonical Wnt signaling pathway [GO:2000052] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.89822 -0.62571 MNSGREPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.3018 0 0 0 0 0 0 0 0 0 0 0 0 Q6XZB0 LIPI_HUMAN Lipase member I (LIPI) (EC 3.1.1.-) (Cancer/testis antigen 17) (CT17) (LPD lipase) (Membrane-associated phosphatidic acid-selective phospholipase A1-beta) (mPA-PLA1 beta) LIPI LPDL PRED5 Homo sapiens (Human) lipid catabolic process [GO:0016042]; phosphatidic acid biosynthetic process [GO:0006654] extracellular space [GO:0005615]; plasma membrane [GO:0005886] carboxylic ester hydrolase activity [GO:0052689]; heparin binding [GO:0008201]; phospholipase activity [GO:0004620] 0.92224 -1.1225 EEVFLNPNTCTPKNT 0 0 0 0 0 0 0 0 0 0 0 9.44995 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6XZF7 DNMBP_HUMAN Dynamin-binding protein (Scaffold protein Tuba) DNMBP ARHGEF36 KIAA1010 TUBA Homo sapiens (Human) aging [GO:0007568]; cilium assembly [GO:0060271]; intracellular signal transduction [GO:0035556]; regulation of cell shape [GO:0008360]; regulation of small GTPase mediated signal transduction [GO:0051056] cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi stack [GO:0005795]; presynapse [GO:0098793]; synapse [GO:0045202] guanyl-nucleotide exchange factor activity [GO:0005085] 0.95898 -1.7378 GIFPEGFVELLGPLR 0 0 0 0 0 0 0 15.7141 0 0 0 0 0 0 0 9.04139 8.91552 0 0 0 0 0 0 0 0 0 0 Q6Y1H2 HACD2_HUMAN Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase 2) (HACD2) (Protein-tyrosine phosphatase-like member B) HACD2 PTPLB Homo sapiens (Human) fatty acid elongation [GO:0030497]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; sphingolipid biosynthetic process [GO:0030148]; very long-chain fatty acid biosynthetic process [GO:0042761] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789] 3-hydroxyacyl-CoA dehydratase activity [GO:0018812]; enzyme binding [GO:0019899] 0.01023 1.9573 GNGGGGGR 0 0 0 0 0 0 0 0 8.75559 0 0 0 0 0 0 0 0 0 0 10.1757 0 0 0 0 0 0 0 Q6Y288 B3GLT_HUMAN "Beta-1,3-glucosyltransferase (Beta3Glc-T) (EC 2.4.1.-) (Beta 3-glucosyltransferase) (Beta-3-glycosyltransferase-like)" B3GLCT B3GALTL B3GTL Homo sapiens (Human) fucose metabolic process [GO:0006004]; protein O-linked fucosylation [GO:0036066] endoplasmic reticulum membrane [GO:0005789] acetylglucosaminyltransferase activity [GO:0008375]; glycosyltransferase activity [GO:0016757] 0.96385 -2.2221 FLNRSQDK 0 0 0 0 0 0 0 0 0 10.3812 0 10.9536 0 0 0 0 0 0 0 0 10.2071 0 0 0 0 0 0 Q6Y2X3 DJC14_HUMAN DnaJ homolog subfamily C member 14 (DnaJ protein homolog 3) (Dopamine receptor-interacting protein of 78 kDa) (DRIP78) (Human DnaJ protein 3) (hDj-3) DNAJC14 DRIP78 HDJ3 Homo sapiens (Human) protein transport [GO:0015031] endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] dopamine receptor binding [GO:0050780] 0.9162 -0.84969 EPKSARYCAECNR 0 0 0 0 0 0 9.74808 10.0034 10.0827 10.3393 0 0 0 0 0 0 0 0 0 0 0 10.9347 0 0 0 0 0 Q6Y7W6 GGYF2_HUMAN GRB10-interacting GYF protein 2 (PERQ amino acid-rich with GYF domain-containing protein 2) (Trinucleotide repeat-containing gene 15 protein) GIGYF2 KIAA0642 PERQ2 TNRC15 Homo sapiens (Human) adult locomotory behavior [GO:0008344]; feeding behavior [GO:0007631]; homeostasis of number of cells within a tissue [GO:0048873]; insulin-like growth factor receptor signaling pathway [GO:0048009]; mitotic G1 DNA damage checkpoint signaling [GO:0031571]; mRNA destabilization [GO:0061157]; multicellular organism growth [GO:0035264]; musculoskeletal movement [GO:0050881]; negative regulation of translation [GO:0017148]; neuromuscular process controlling balance [GO:0050885]; post-embryonic development [GO:0009791]; post-transcriptional gene silencing [GO:0016441]; protein metabolic process [GO:0019538]; spinal cord motor neuron differentiation [GO:0021522] cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; perikaryon [GO:0043204]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]; vesicle [GO:0031982] cadherin binding [GO:0045296]; proline-rich region binding [GO:0070064]; RNA binding [GO:0003723] 0.96093 -2.0584 EEQNGEDEDGGWR 0 0 0 0 0 0 0 0 0 0 0 10.3577 0 0 0 0 0 0 0 0 9.80292 0 0 0 0 0 10.6009 Q6YHK3 CD109_HUMAN CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109) CD109 CPAMD7 Homo sapiens (Human) hair follicle development [GO:0001942]; keratinocyte proliferation [GO:0043616]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of peptidase activity [GO:0010466]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; osteoclast fusion [GO:0072675]; protein phosphorylation [GO:0006468]; regulation of keratinocyte differentiation [GO:0045616]; stem cell proliferation [GO:0072089] cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092] serine-type endopeptidase inhibitor activity [GO:0004867]; transforming growth factor beta binding [GO:0050431] 0.96312 -2.126 KVEYDHGK 11.2632 0 10.8584 9.15821 9.07762 9.09011 0 0 10.5039 0 0 11.0924 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6YHU6 THADA_HUMAN Thyroid adenoma-associated protein (Gene inducing thyroid adenomas protein) THADA GITA KIAA1767 Homo sapiens (Human) adaptive thermogenesis [GO:1990845]; lipid homeostasis [GO:0055088]; negative regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901895]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; tRNA methylation [GO:0030488]; tRNA nucleoside ribose methylation [GO:0002128] cytoplasmic side of endoplasmic reticulum membrane [GO:0098554] enzyme regulator activity [GO:0030234] 0.59196 0.44853 HLFCLLSK 0 0 11.6522 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6YN16 HSDL2_HUMAN Hydroxysteroid dehydrogenase-like protein 2 (EC 1.-.-.-) (Short chain dehydrogenase/reductase family 13C member 1) HSDL2 C9orf99 SDR13C1 Homo sapiens (Human) membrane [GO:0016020]; mitochondrion [GO:0005739]; peroxisome [GO:0005777] oxidoreductase activity [GO:0016491] 0.96185 -2.4568 GEIAVNALWPK 12.671 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0934 11.9799 12.7402 0 0 0 0 0 0 0 10.3437 0 0 Q6ZMG9 CERS6_HUMAN Ceramide synthase 6 (CerS6) (LAG1 longevity assurance homolog 6) (Sphingoid base N-palmitoyltransferase CERS6) (EC 2.3.1.291) CERS6 LASS6 Homo sapiens (Human) ceramide biosynthetic process [GO:0046513]; inflammatory response [GO:0006954]; sphingolipid biosynthetic process [GO:0030148] endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] DNA binding [GO:0003677]; sphingosine N-acyltransferase activity [GO:0050291] 0.74437 0.32062 FSFYLYVFTYGVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.76258 0 9.85758 0 0 0 0 0 0 Q6ZMI0 PPR21_HUMAN Protein phosphatase 1 regulatory subunit 21 (Coiled-coil domain-containing protein 128) (KLRAQ motif-containing protein 1) PPP1R21 CCDC128 KLRAQ1 Homo sapiens (Human) early endosome [GO:0005769]; membrane [GO:0016020] 0.94063 -1.3285 KPLLESVPYEEALANR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6829 10.7917 Q6ZMI3 GLDN_HUMAN Gliomedin [Cleaved into: Gliomedin shedded ectodomain] GLDN COLM UNQ9339/PRO34011 Homo sapiens (Human) clustering of voltage-gated sodium channels [GO:0045162]; microvillus organization [GO:0032528]; signal transduction [GO:0007165] axon [GO:0030424]; cell surface [GO:0009986]; collagen trimer [GO:0005581]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] protein binding involved in heterotypic cell-cell adhesion [GO:0086080] 0.96341 -2.0992 ARGAEGGRGDAGWGLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.58768 0 0 0 0 0 0 0 0 0 9.85123 Q6ZMJ2 SCAR5_HUMAN Scavenger receptor class A member 5 (Scavenger receptor hlg) SCARA5 UNQ2938/PRO28700 Homo sapiens (Human) cellular response to heat [GO:0034605]; endocytosis [GO:0006897]; intracellular iron ion homeostasis [GO:0006879]; iron ion transmembrane transport [GO:0034755]; protein homotrimerization [GO:0070207] cell surface [GO:0009986]; plasma membrane [GO:0005886] ferritin receptor activity [GO:0070287]; scavenger receptor activity [GO:0005044] 0.23077 0.85614 RWGTVCDDGWDK 0 0 0 0 0 0 0 0 0 0 10.4216 0 0 0 0 0 10.1266 0 0 0 0 0 0 0 0 0 0 Q6ZMM2 ATL5_HUMAN ADAMTS-like protein 5 (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6) ADAMTSL5 THSD6 Homo sapiens (Human) extracellular matrix organization [GO:0030198] extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; microfibril [GO:0001527] heparin binding [GO:0008201]; microfibril binding [GO:0050436] 0.95467 -1.5075 IQLVYKNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7998 0 0 0 0 0 0 0 0 0 0 0 Q6ZMN7 PZRN4_HUMAN PDZ domain-containing RING finger protein 4 (Ligand of Numb protein X 4) (SEMACAP3-like protein) PDZRN4 LNX4 SEMCAP3L Homo sapiens (Human) metal ion binding [GO:0046872] 0.92023 -0.90311 CSEPKMEWK 17.7157 0 0 13.2304 0 13.2894 0 0 0 0 12.5202 0 13.0144 12.7782 10.3997 0 0 0 0 0 0 8.79133 0 0 0 0 0 Q6ZMN8 CCNI2_HUMAN Cyclin-I2 CCNI2 Homo sapiens (Human) mitotic cell cycle phase transition [GO:0044772]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079] cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; nucleus [GO:0005634] cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538] 0.96427 -2.4234 GTAPAGK 0 0 0 0 0 0 0 0 0 0 11.1155 0 0 0 0 0 0 0 0 0 9.3526 0 0 0 10.1262 0 0 Q6ZMP0 THSD4_HUMAN Thrombospondin type-1 domain-containing protein 4 (A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6) (ADAMTS-like protein 6) (ADAMTSL-6) THSD4 UNQ9334/PRO34005 Homo sapiens (Human) elastic fiber assembly [GO:0048251]; extracellular matrix organization [GO:0030198]; microfibril assembly [GO:0160054] collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; microfibril [GO:0001527] hydrolase activity [GO:0016787] 0.96256 -2.1672 GTIGPGK 0 0 0 9.12606 9.40303 9.33602 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4583 0 10.3453 0 0 Q6ZMQ8 LMTK1_HUMAN Serine/threonine-protein kinase LMTK1 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (Lemur tyrosine kinase 1) (p35-binding protein) (p35BP) AATK AATYK KIAA0641 LMR1 LMTK1 Homo sapiens (Human) brain development [GO:0007420]; peptidyl-tyrosine autophosphorylation [GO:0038083] membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713] 0.96785 -2.9341 EIGRGWFGK 0 0 0 0 0 0 0 0 0 0 0 0 10.2329 0 0 0 0 0 0 0 0 0 0 0 9.51592 0 0 Q6ZMR5 TM11A_HUMAN Transmembrane protease serine 11A (EC 3.4.21.-) (Airway trypsin-like protease 1) (Epidermal type-II transmembrane serine protease) (Esophageal cancer-susceptibility gene 1 protein) TMPRSS11A ECRG1 HATL1 HESP Homo sapiens (Human) cell cycle [GO:0007049]; proteolysis [GO:0006508] extracellular region [GO:0005576]; plasma membrane [GO:0005886] serine-type endopeptidase activity [GO:0004252] 0.96364 -2.1322 EYDIAVVQVSSRVTFSDDIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.0905 0 0 0 11.0963 0 9.19643 13.9248 0 0 Q6ZMS4 ZN852_HUMAN Zinc finger protein 852 ZNF852 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.78094 0.26189 LHTSEKPYK 0 0 0 0 0 0 0 8.85265 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZMS7 ZN783_HUMAN Zinc finger protein 783 ZNF783 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] DNA binding [GO:0003677]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872] 0.96067 -1.8027 ELYKHVMR 0 0 0 0 0 0 0 0 0 9.17515 0 9.08252 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZMT1 STAC2_HUMAN SH3 and cysteine-rich domain-containing protein 2 (24b2/STAC2) (Src homology 3 and cysteine-rich domain-containing protein 2) STAC2 Homo sapiens (Human) positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; skeletal muscle contraction [GO:0003009] cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; sarcolemma [GO:0042383] metal ion binding [GO:0046872] 0.95478 -1.5076 DADGFIRVSSGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3329 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZMT4 KDM7A_HUMAN Lysine-specific demethylase 7A (JmjC domain-containing histone demethylation protein 1D) (Lysine-specific demethylase 7) ([histone H3]-dimethyl-L-lysine9 demethylase 7A) (EC 1.14.11.65) KDM7A JHDM1D KDM7 KIAA1718 Homo sapiens (Human) midbrain development [GO:0030901]; positive regulation of DNA-templated transcription [GO:0045893]; protein demethylation [GO:0006482]; regulation of transcription by RNA polymerase II [GO:0006357] nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 2-oxoglutarate-dependent dioxygenase activity [GO:0016706]; histone demethylase activity [GO:0032452]; histone H3K27me2/H3K27me3 demethylase activity [GO:0071558]; histone H3K36 demethylase activity [GO:0051864]; histone H3K9 demethylase activity [GO:0032454]; histone H3K9me/H3K9me2 demethylase activity [GO:0140683]; histone H4K20 demethylase activity [GO:0035575]; iron ion binding [GO:0005506]; methylated histone binding [GO:0035064]; transcription coregulator activity [GO:0003712]; zinc ion binding [GO:0008270] 0.90215 -0.70288 HLQPSSTVPEWRAK 0 0 0 0 0 0 0 9.19867 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8486 Q6ZMT9 DTHD1_HUMAN Death domain-containing protein 1 DTHD1 Homo sapiens (Human) signal transduction [GO:0007165] 0.88986 -0.47043 ENNTSLNGRVLGQEESQNK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.63192 0 0 0 0 0 10.1445 9.44593 0 9.55865 0 10.275 0 0 Q6ZMU1 C3P1_HUMAN Putative protein C3P1 C3P1 Homo sapiens (Human) extracellular space [GO:0005615] endopeptidase inhibitor activity [GO:0004866] 0.84289 0.15187 SFFVDLK 0 0 0 0 0 0 0 0 0 0 10.8338 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZMU5 TRI72_HUMAN Tripartite motif-containing protein 72 (Mitsugumin-53) (Mg53) TRIM72 MG53 Homo sapiens (Human) exocytosis [GO:0006887]; muscle organ development [GO:0007517]; muscle system process [GO:0003012]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of insulin-like growth factor receptor signaling pathway [GO:0043569]; negative regulation of myotube differentiation [GO:0010832]; plasma membrane repair [GO:0001778]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567] cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; sarcolemma [GO:0042383] identical protein binding [GO:0042802]; phosphatidylserine binding [GO:0001786]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.95429 -1.5305 SPERRPTR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.71498 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZMV7 LEKR1_HUMAN Protein LEKR1 LEKR1 Homo sapiens (Human) 0.87001 0.066001 VCKYCGVSYLILHEFK 0 0 0 10.6546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZMV9 KIF6_HUMAN Kinesin-like protein KIF6 KIF6 C6orf102 Homo sapiens (Human) microtubule-based movement [GO:0007018] cytoplasm [GO:0005737]; kinesin complex [GO:0005871]; microtubule [GO:0005874] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777] 0.94014 -1.3302 ALGESINEAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.71642 0 0 0 0 0 Q6ZMW2 ZN782_HUMAN Zinc finger protein 782 ZNF782 Homo sapiens (Human) nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.88032 0.014402 NSPEDSQPDEISEK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.72238 9.97212 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZMW3 EMAL6_HUMAN Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like) EML6 EML5L Homo sapiens (Human) cytoplasm [GO:0005737]; microtubule [GO:0005874] microtubule binding [GO:0008017] 0.10866 1.1358 AHDGPVFAMYALDK 0 0 0 9.258 0 0 0 0 0 0 0 0 0 0 9.76658 10.6137 0 10.5335 0 0 0 0 0 0 0 0 0 Q6ZMZ3 SYNE3_HUMAN Nesprin-3 (KASH domain-containing protein 3) (KASH3) (Nuclear envelope spectrin repeat protein 3) SYNE3 C14orf139 C14orf49 LINC00341 Homo sapiens (Human) cytoskeleton organization [GO:0007010]; establishment of protein localization to membrane [GO:0090150]; nuclear migration [GO:0007097]; regulation of cell shape [GO:0008360] cytoplasm [GO:0005737]; meiotic nuclear membrane microtubule tethering complex [GO:0034993]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; rough endoplasmic reticulum [GO:0005791] actin filament binding [GO:0051015]; cytoskeleton-nuclear membrane anchor activity [GO:0140444] 0.96894 -3.3379 DFGAAFEPLQRK 0 0 0 0 0 0 0 0 0 0 0 9.65939 0 0 0 9.82225 0 0 0 0 0 0 0 0 0 0 0 Q6ZN06 ZN813_HUMAN Zinc finger protein 813 ZNF813 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.9697 -5.4246 CNECGKGFNR 0 0 0 0 0 0 0 0 0 0 0 0 8.91319 0 0 0 0 0 0 0 0 9.14583 0 0 0 0 0 Q6ZN08 ZNF66_HUMAN Putative zinc finger protein 66 (Zinc finger protein 66 pseudogene) ZNF66 ZNF66P Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.94612 -1.3445 AFSRSSILTTHK 8.92083 0 0 0 0 0 0 0 0 10.0908 10.3348 0 0 0 0 11.6529 0 0 0 0 0 0 0 0 0 0 0 Q6ZN11 ZN793_HUMAN Zinc finger protein 793 ZNF793 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.95549 -1.6357 CRECGKSFSQK 0 0 0 0 0 0 0 0 0 0 9.46365 0 0 0 0 0 0 0 0 9.22125 0 0 0 0 0 0 0 Q6ZN16 M3K15_HUMAN Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 3) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15) MAP3K15 ASK3 Homo sapiens (Human) protein phosphorylation [GO:0006468] ATP binding [GO:0005524]; MAP kinase kinase kinase activity [GO:0004709]; metal ion binding [GO:0046872]; protein serine kinase activity [GO:0106310] 0.96903 -4.4423 DQGLFLLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.89197 0 0 0 9.15515 0 0 0 0 Q6ZN17 LN28B_HUMAN Protein lin-28 homolog B (Lin-28B) LIN28B CSDD2 Homo sapiens (Human) miRNA catabolic process [GO:0010587]; negative regulation of pre-miRNA processing [GO:2000632]; negative regulation of primary miRNA processing [GO:2000635]; positive regulation of miRNA catabolic process [GO:2000627]; pre-miRNA processing [GO:0031054]; RNA 3'-end processing [GO:0031123]; RNA destabilization [GO:0050779] cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] RNA binding [GO:0003723]; sequence-specific double-stranded DNA binding [GO:1990837]; zinc ion binding [GO:0008270] 0.90254 -0.6979 GGGEEPGK 0 0 0 0 0 0 0 0 0 8.81865 0 11.9083 0 0 0 0 0 0 11.1673 0 0 0 0 0 0 0 0 Q6ZN19 ZN841_HUMAN Zinc finger protein 841 ZNF841 Homo sapiens (Human) nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.92373 -1.0289 HSQGDVENK 0 0 0 0 0 0 0 0 0 0 8.68482 0 0 0 0 0 0 0 0 0 0 0 10.0686 0 0 0 0 Q6ZN28 MACC1_HUMAN Metastasis-associated in colon cancer protein 1 (SH3 domain-containing protein 7a5) MACC1 Homo sapiens (Human) positive regulation of cell division [GO:0051781]; positive regulation of transcription by RNA polymerase II [GO:0045944] cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nucleus [GO:0005634] growth factor activity [GO:0008083] 0.96259 -2.172 IGLVHCKNVK 0 9.04396 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0333 9.75072 0 9.75129 0 0 0 0 0 Q6ZN44 UNC5A_HUMAN Netrin receptor UNC5A (Protein unc-5 homolog 1) (Protein unc-5 homolog A) UNC5A KIAA1976 UNC5H1 Homo sapiens (Human) anterior/posterior axon guidance [GO:0033564]; apoptotic process [GO:0006915]; netrin-activated signaling pathway [GO:0038007]; neuron projection development [GO:0031175] membrane raft [GO:0045121]; neuron projection membrane [GO:0032589]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886] netrin receptor activity [GO:0005042] 0.89837 -0.58181 AYIRIAYLR 10.1239 0 0 0 0 0 0 0 0 0 0 12.0015 0 0 0 0 0 0 0 0 0 0 0 0 8.40062 0 0 Q6ZN55 ZN574_HUMAN Zinc finger protein 574 ZNF574 Homo sapiens (Human) nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96139 -2.0545 LREHRCAAAAAQAPR 0 0 0 0 0 0 9.65834 0 12.4647 0 0 0 0 0 0 11.9799 0 0 0 0 0 0 0 0 0 0 0 Q6ZN66 GBP6_HUMAN Guanylate-binding protein 6 (EC 3.6.5.-) (GTP-binding protein 6) (GBP-6) (Guanine nucleotide-binding protein 6) GBP6 Homo sapiens (Human) cellular response to type II interferon [GO:0071346]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; defense response to protozoan [GO:0042832]; immune response [GO:0006955] cytoplasmic vesicle [GO:0031410]; extracellular exosome [GO:0070062] GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.88551 -0.37479 IEQDYWQVPRK 0 0 0 0 0 0 15.4566 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZN68 D19P2_HUMAN Putative C-mannosyltransferase DPY19L2P2 (EC 2.4.1.-) (Dpy-19-like protein 2 pseudogene 2) (Protein dpy-19 homolog 2-like 2) DPY19L2P2 Homo sapiens (Human) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan [GO:0018406]; spermatid development [GO:0007286] nuclear inner membrane [GO:0005637] mannosyltransferase activity [GO:0000030] 0.84716 0.16822 IEPLNEVQSCEGLR 11.2916 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZN84 CCD81_HUMAN Coiled-coil domain-containing protein 81 CCDC81 Homo sapiens (Human) centrosome [GO:0005813]; cytoplasm [GO:0005737] 0.96831 -2.7776 AGQEMCYVCLQR 13.009 12.8762 13.1805 9.72204 10.2348 9.85301 12.5024 9.76625 12.4991 12.1548 12.6466 12.6214 10.8312 10.9555 10.9555 11.8411 11.5292 11.6845 0 0 0 0 0 0 9.41325 0 0 Q6ZNA1 ZN836_HUMAN Zinc finger protein 836 ZNF836 Homo sapiens (Human) nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.92601 -0.96498 QNSNLVNHQR 0 0 0 0 0 0 0 0 9.7118 0 0 0 0 0 0 10.9637 0 0 0 0 0 0 0 0 0 0 0 Q6ZNA4 RN111_HUMAN E3 ubiquitin-protein ligase Arkadia (EC 2.3.2.27) (RING finger protein 111) (hRNF111) (RING-type E3 ubiquitin transferase Arkadia) RNF111 Homo sapiens (Human) global genome nucleotide-excision repair [GO:0070911]; pattern specification process [GO:0007389]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; ubiquitin-dependent SMAD protein catabolic process [GO:0030579] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991] metal ion binding [GO:0046872]; SMAD binding [GO:0046332]; SUMO polymer binding [GO:0032184]; ubiquitin protein ligase activity [GO:0061630] 0.87069 0.056713 KVTTDWFSQR 0 0 0 0 0 0 10.4646 9.82279 0 0 0 0 0 0 0 0 0 0 0 10.8864 9.75664 0 9.84428 0 0 0 0 Q6ZNB6 NFXL1_HUMAN NF-X1-type zinc finger protein NFXL1 (Ovarian zinc finger protein) (hOZFP) NFXL1 OZFP Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] chromatin [GO:0000785]; membrane [GO:0016020]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; zinc ion binding [GO:0008270]" 0.1338 1.0579 CNCGNTK 10.223 10.2282 10.1678 0 10.1625 0 10.1614 10.2758 10.1866 10.5317 10.6359 10.8304 0 9.39313 9.31268 9.8596 0 0 0 9.56362 8.21922 0 0 0 0 0 0 Q6ZNC4 ZN704_HUMAN Zinc finger protein 704 ZNF704 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837] 0.43053 0.65799 KMSHQHVFSLAMEEDVK 0 0 0 0 10.8035 10.572 0 0 0 0 0 0 0 0 11.1652 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZNC8 MBOA1_HUMAN Lysophospholipid acyltransferase 1 (LPLAT 1) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.n7) (1-acylglycerophosphoserine O-acyltransferase MBOAT1) (EC 2.3.1.n6) (Lysophosphatidylserine acyltransferase) (LPSAT) (Lyso-PS acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 1) (O-acyltransferase domain-containing protein 1) MBOAT1 OACT1 Homo sapiens (Human) lipid modification [GO:0030258]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid biosynthetic process [GO:0008654]; regulation of neuron projection development [GO:0010975] endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] 1-acylglycerol-3-phosphate O-acyltransferase activity [GO:0003841]; 1-acylglycerophosphocholine O-acyltransferase activity [GO:0047184]; 1-acylglycerophosphoethanolamine O-acyltransferase activity [GO:0106262]; 1-acylglycerophosphoserine O-acyltransferase activity [GO:0106263]; 2-acylglycerol-3-phosphate O-acyltransferase activity [GO:0047144]; acyltransferase activity [GO:0016746] 0.91411 -0.8001 LLEVNWKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.38489 0 0 0 0 Q6ZNE9 RUFY4_HUMAN RUN and FYVE domain-containing protein 4 RUFY4 Homo sapiens (Human) autophagosome assembly [GO:0000045]; cellular response to interleukin-4 [GO:0071353]; positive regulation of macroautophagy [GO:0016239] autophagosome [GO:0005776]; cytoplasmic vesicle [GO:0031410] metal ion binding [GO:0046872]; phosphatidylinositol-3-phosphate binding [GO:0032266] 0.96974 -4.7508 DLVQAMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4864 9.19832 0 0 0 0 0 0 9.08513 0 0 0 0 Q6ZNF0 ACP7_HUMAN Acid phosphatase type 7 (EC 3.1.3.2) (Purple acid phosphatase long form) ACP7 PAPL PAPL1 Homo sapiens (Human) extracellular region [GO:0005576] acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872] 0.96931 -3.5707 LYIHRVTLR 0 0 0 9.61298 0 0 0 0 0 0 0 0 10.4949 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZNG0 ZN620_HUMAN Zinc finger protein 620 ZNF620 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.95597 -1.5931 AFSSSSVFLQHQRFHTGEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.26256 0 0 0 0 0 0 0 0 0 0 0 Q6ZNG2 DBX2_HUMAN Homeobox protein DBX2 (Developing brain homeobox protein 2) DBX2 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]" 0.95056 -1.4084 AVFSEDQRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.72804 0 0 0 9.63517 0 Q6ZNG9 KRBA2_HUMAN KRAB-A domain-containing protein 2 KRBA2 Homo sapiens (Human) DNA integration [GO:0015074]; regulation of DNA-templated transcription [GO:0006355] nucleic acid binding [GO:0003676] 0.96974 -3.4509 EKYFQTIKEVK 0 0 0 0 0 0 0 0 0 9.59928 0 0 0 0 9.85435 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZNJ1 NBEL2_HUMAN Neurobeachin-like protein 2 NBEAL2 KIAA0540 UNQ253/PRO290 Homo sapiens (Human) platelet formation [GO:0030220]; protein localization [GO:0008104] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; ficolin-1-rich granule membrane [GO:0101003]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821] protein kinase binding [GO:0019901] 0.96199 -2.5858 GLLSVVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.8662 0 0 0 0 0 0 0 0 0 Q6ZNW5 GDPP1_HUMAN GDP-D-glucose phosphorylase 1 (EC 2.7.7.78) GDPGP1 C15orf58 Homo sapiens (Human) glucose metabolic process [GO:0006006] cytoplasm [GO:0005737] GDP-D-glucose phosphorylase activity [GO:0080048]; guanyl-nucleotide exchange factor activity [GO:0005085]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166] 0.77539 0.26496 GPGPDLESLISR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0374 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZP01 RBM44_HUMAN RNA-binding protein 44 (RNA-binding motif protein 44) RBM44 Homo sapiens (Human) cytoplasm [GO:0005737]; intercellular bridge [GO:0045171] protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723] 0.89825 -0.59434 ACFTTSR 9.64153 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.71855 0 0 0 0 Q6ZP68 ATPUN_HUMAN Putative protein ATP11AUN (Putative ATP11A upstream neighbor protein) ATP11AUN C13orf35 Homo sapiens (Human) 0.57199 0.48048 VTVQTDDSNK 0 0 0 0 0 0 8.57928 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZP82 CC141_HUMAN Coiled-coil domain-containing protein 141 (Coiled-coil protein associated with myosin II and DISC1) CCDC141 CAMDI Homo sapiens (Human) centrosome localization [GO:0051642]; cerebral cortex radially oriented cell migration [GO:0021799] centrosome [GO:0005813]; cytoplasm [GO:0005737] 0.96705 -2.7357 ERIQDYEDILYK 0 9.8603 12.0334 0 9.58278 0 10.9028 0 0 0 0 10.373 0 0 0 10.308 10.2186 9.35277 0 0 0 8.6762 0 0 10.4407 10.166 10.4008 Q6ZPD9 D19L3_HUMAN Probable C-mannosyltransferase DPY19L3 (EC 2.4.1.-) (Dpy-19-like protein 3) (Protein dpy-19 homolog 3) DPY19L3 Homo sapiens (Human) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan [GO:0018406] nuclear inner membrane [GO:0005637] mannosyltransferase activity [GO:0000030] 0.94894 -1.372 MMSIRQRR 0 0 0 0 0 9.65085 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6188 0 0 Q6ZQQ2 S31D1_HUMAN Spermatogenesis-associated protein 31D1 (Protein FAM75D1) SPATA31D1 FAM75D1 Homo sapiens (Human) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] membrane [GO:0016020] 0.96837 -2.7696 ATADIQQLLSWESLK 0 0 0 0 0 0 0 0 0 0 0 10.145 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZQQ6 WDR87_HUMAN WD repeat-containing protein 87 (Testis development protein NYD-SP11) WDR87 Homo sapiens (Human) 0.96897 -6.7345 AWKEEWEK 0 0 12.0911 11.2824 0 0 12.3236 9.78126 10.8489 0 13.5412 0 10.3705 0 0 11.3518 0 0 0 10.857 9.46701 9.0959 0 0 0 0 0 Q6ZQT0 YD023_HUMAN Putative uncharacterized protein FLJ45035 Homo sapiens (Human) 0.72753 0.34655 LSPVSEMFGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1922 0 0 0 0 0 0 9.8298 0 0 0 Q6ZQY2 LR74B_HUMAN Leucine-rich repeat-containing protein 74B LRRC74B Homo sapiens (Human) 0.56653 0.5019 ALASSLSSNPYVK 0 0 0 0 9.13175 0 0 0 0 0 0 0 0 0 9.12265 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZQY3 GADL1_HUMAN Acidic amino acid decarboxylase GADL1 (Aspartate 1-decarboxylase) (ADC) (HuADC) (EC 4.1.1.11) (Cysteine sulfinic acid decarboxylase) (CSADC) (HuCSADC) (EC 4.1.1.29) (Glutamate decarboxylase-like protein 1) GADL1 Homo sapiens (Human) carboxylic acid metabolic process [GO:0019752] cytoplasm [GO:0005737]; cytosol [GO:0005829] aspartate 1-decarboxylase activity [GO:0004068]; carboxy-lyase activity [GO:0016831]; pyridoxal phosphate binding [GO:0030170]; sulfinoalanine decarboxylase activity [GO:0004782] 0.96984 -3.087 LNLVAPAIKER 0 0 0 11.3286 0 0 0 0 0 9.39433 0 0 0 0 0 0 9.59781 0 0 0 9.77136 0 0 0 0 0 0 Q6ZR08 DYH12_HUMAN Dynein axonemal heavy chain 12 (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12) (Dynein axonemal heavy chain 7-like) (Dynein heavy chain domain-containing protein 2) DNAH12 DHC3 DLP12 DNAH12L DNAH7L DNAHC3 DNHD2 HDHC3 HL19 Homo sapiens (Human) microtubule-based movement [GO:0007018] axonemal dynein complex [GO:0005858]; microtubule [GO:0005874] ATP binding [GO:0005524]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; minus-end-directed microtubule motor activity [GO:0008569] 0.969 -4.1974 ARTVGIEELILR 0 13.9596 9.57854 8.85891 9.99972 9.05645 9.05322 9.23795 0 9.4368 11.3028 0 0 0 0 9.79006 0 0 0 10.0367 0 0 0 11.631 0 0 9.79888 Q6ZR37 PKHG7_HUMAN Pleckstrin homology domain-containing family G member 7 (PH domain-containing family G member 7) PLEKHG7 C12orf74 Homo sapiens (Human) Rho protein signal transduction [GO:0007266] guanyl-nucleotide exchange factor activity [GO:0005085] 0.96261 -2.5367 DLEGKVKWLDNFQK 0 0 0 0 0 0 9.25831 0 0 0 0 0 0 0 0 0 11.1228 0 0 0 0 0 0 9.58237 0 0 0 Q6ZRF7 ZN818_HUMAN Putative zinc finger protein 818 ZNF818P ZNF818 Homo sapiens (Human) nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.1642 0.98521 NHMNMTYMAK 0 0 0 0 8.47249 0 0 0 0 0 0 0 0 0 0 0 10.3318 0 0 0 0 0 0 0 0 0 0 Q6ZRF8 RN207_HUMAN RING finger protein 207 RNF207 C1orf188 Homo sapiens (Human) cell-cell signaling involved in cardiac conduction [GO:0086019]; positive regulation of delayed rectifier potassium channel activity [GO:1902261]; positive regulation of gene expression [GO:0010628]; positive regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization [GO:1903954]; positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1903762]; regulation of cardiac muscle contraction [GO:0055117]; regulation of heart looping [GO:1901207] perinuclear region of cytoplasm [GO:0048471] Hsp70 protein binding [GO:0030544]; protein-folding chaperone binding [GO:0051087]; transmembrane transporter binding [GO:0044325]; zinc ion binding [GO:0008270] 0.92171 -1.1335 NMDHHRSKQK 13.0645 0 0 9.04442 0 9.14919 11.7106 0 0 0 0 0 0 0 0 11.5982 0 0 0 0 0 0 0 0 0 0 0 Q6ZRH7 CTSRG_HUMAN Cation channel sperm-associated auxiliary subunit gamma CATSPERG C19orf15 Homo sapiens (Human) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] CatSper complex [GO:0036128]; motile cilium [GO:0031514]; plasma membrane [GO:0005886]; sperm principal piece [GO:0097228] 0.96907 -3.3135 AEPKEAVER 0 0 0 0 0 0 0 0 0 10.8392 10.2797 0 0 0 0 0 0 0 10.0474 0 0 0 0 9.11634 0 0 0 Q6ZRI0 OTOG_HUMAN Otogelin OTOG OTGN Homo sapiens (Human) L-arabinose metabolic process [GO:0046373] apical plasma membrane [GO:0016324]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615] alpha-L-arabinofuranosidase activity [GO:0046556] 0.95473 -1.5736 AQGHGLCGICDGDAANDLTLK 0 0 0 8.76039 9.21888 0 0 11.6958 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZRI6 CO039_HUMAN Uncharacterized protein C15orf39 C15orf39 FP6578 Homo sapiens (Human) cytosol [GO:0005829] 0.95989 -1.9806 AEKRPLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0136 0 0 0 0 0 0 0 Q6ZRI8 RHG36_HUMAN Rho GTPase-activating protein 36 ARHGAP36 Homo sapiens (Human) signal transduction [GO:0007165] GTPase activator activity [GO:0005096] 0.69686 0.37749 EKEAKTGVSYFFP 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1316 0 Q6ZRK6 CCD73_HUMAN Coiled-coil domain-containing protein 73 (Sarcoma antigen NY-SAR-79) CCDC73 Homo sapiens (Human) 0.96233 -2.4866 ENNQTLERDNELQREK 0 10.1581 0 9.53125 10.8035 10.4915 0 0 0 0 0 0 0 0 0 0 10.9976 0 0 0 10.9913 0 0 0 0 0 0 Q6ZRN7 YP029_HUMAN Putative uncharacterized protein FLJ46214 Homo sapiens (Human) 0.84278 0.15187 LCRPPGR 0 0 0 0 0 0 0 9.84389 10.0627 10.7299 10.8338 10.8809 0 0 0 0 0 10.5572 0 0 0 0 0 0 0 0 0 Q6ZRQ5 MMS22_HUMAN Protein MMS22-like (Methyl methanesulfonate-sensitivity protein 22-like) MMS22L C6orf167 Homo sapiens (Human) chromatin organization [GO:0006325]; double-strand break repair via homologous recombination [GO:0000724]; protein localization to chromatin [GO:0071168]; replication fork processing [GO:0031297] cytosol [GO:0005829]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861] single-stranded DNA binding [GO:0003697] 0.95975 -1.9714 QLVKLTR 11.3202 11.557 0 8.47889 0 8.45837 11.4902 11.6826 0 0 0 0 0 0 10.1113 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZRR7 LRRC9_HUMAN Leucine-rich repeat-containing protein 9 LRRC9 Homo sapiens (Human) cytoplasm [GO:0005737] 0.969 -3.3756 DLKFDDEVIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.623 10.713 9.24631 0 9.44636 0 0 0 0 0 0 Q6ZRS2 SRCAP_HUMAN Helicase SRCAP (EC 3.6.4.-) (Domino homolog 2) (Snf2-related CBP activator) SRCAP KIAA0309 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] Golgi apparatus [GO:0005794]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; Swr1 complex [GO:0000812] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent chromatin remodeler activity [GO:0140658]; DNA binding [GO:0003677]; helicase activity [GO:0004386]; histone acetyltransferase activity [GO:0004402]; histone binding [GO:0042393]; transcription coactivator activity [GO:0003713] 0.97017 -4.1428 CHRIGQTR 0 0 0 0 12.4011 0 0 0 0 0 0 0 0 0 0 9.65548 0 0 0 0 0 0 10.3327 9.42436 10.4441 0 0 Q6ZRS4 ITPI1_HUMAN Protein ITPRID1 (Coiled-coil domain-containing protein 129) (ITPR-interacting domain-containing protein 1) ITPRID1 CCDC129 Homo sapiens (Human) signaling receptor binding [GO:0005102] 0.83005 0.20641 MSPSSSAWAK 0 0 10.3971 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZRU5 YQ032_HUMAN Putative uncharacterized protein FLJ46089 Homo sapiens (Human) extracellular region [GO:0005576] 0.89731 -0.62857 ITPSACL 0 10.167 0 0 0 0 0 0 0 11.1935 11.3921 11.2153 0 0 0 10.7809 0 0 0 10.1518 0 0 0 0 0 0 0 Q6ZRV2 FA83H_HUMAN Protein FAM83H FAM83H Homo sapiens (Human) biomineral tissue development [GO:0031214]; intermediate filament cytoskeleton organization [GO:0045104]; positive regulation of cell migration [GO:0030335]; protein localization to cytoskeleton [GO:0044380]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856] keratin filament binding [GO:1990254]; protein kinase binding [GO:0019901] 0.95955 -1.9486 GSPTTGFIEQKGSPTSAYPER 0 0 0 0 0 0 0 0 0 0 0 0 9.46005 0 0 0 12.5065 0 0 0 0 10.1739 0 0 10.6964 0 0 Q6ZRY4 RBPS2_HUMAN "RNA-binding protein with multiple splicing 2 (RNA binding protein, mRNA processing factor 2)" RBPMS2 Homo sapiens (Human) embryonic digestive tract morphogenesis [GO:0048557]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of smooth muscle cell proliferation [GO:0048661] cytoplasm [GO:0005737] identical protein binding [GO:0042802]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803] 0.72995 0.332 AGAEAAK 0 0 9.50353 0 0 0 0 0 0 0 8.84969 8.45783 0 0 0 0 0 9.69579 10.6364 0 0 0 0 8.38297 0 10.3621 0 Q6ZS02 DMP46_HUMAN Putative GED domain-containing protein DNM1P46 (DNM1 pseudogene 46) DNM1P46 C15orf51 Homo sapiens (Human) 0.94359 -1.3363 RDSRGNEK 0 0 0 0 0 0 0 0 0 0 11.5543 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZS11 RINL_HUMAN Ras and Rab interactor-like protein RINL Homo sapiens (Human) endocytosis [GO:0006897]; protein transport [GO:0015031] actin cytoskeleton [GO:0015629]; cytosol [GO:0005829]; endocytic vesicle [GO:0030139]; ruffle [GO:0001726] GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; small GTPase binding [GO:0031267] 0.90573 -0.72259 GLSSEAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.68342 Q6ZS30 NBEL1_HUMAN Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein) NBEAL1 ALS2CR16 ALS2CR17 Homo sapiens (Human) protein localization [GO:0008104] cytosol [GO:0005829]; membrane [GO:0016020] protein kinase binding [GO:0019901] 0.92179 -1.1102 EAKTNPVTAENAFR 0 0 0 0 0 0 0 0 0 0 10.5083 0 0 0 0 0 0 9.26139 0 0 0 0 0 9.05515 0 0 9.27561 Q6ZS46 YF009_HUMAN Putative uncharacterized protein FLJ45840 Homo sapiens (Human) 0.9614 -2.5603 AGLPEGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.79077 Q6ZS49 YQ050_HUMAN Putative uncharacterized protein FLJ45831 Homo sapiens (Human) extracellular space [GO:0005615] 0.88301 -0.27388 LGPATALGNSGRVE 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.76155 0 0 0 0 0 0 0 0 0 0 0 Q6ZS62 COLC1_HUMAN Colorectal cancer-associated protein 1 COLCA1 C11orf92 Homo sapiens (Human) membrane [GO:0016020] 0.87025 0.034255 EASLWFVAQH 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.62044 0 0 0 0 0 0 0 0 0 0 0 Q6ZS72 PEAK3_HUMAN Protein PEAK3 PEAK3 C19orf35 Homo sapiens (Human) protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360] actin cytoskeleton [GO:0015629]; focal adhesion [GO:0005925] protein kinase activity [GO:0004672]; protein self-association [GO:0043621] 0.73024 0.33692 TIYARLRAR 0 0 0 0 10.7928 0 0 0 0 0 0 0 0 0 0 0 0 10.1165 0 0 0 0 0 0 0 0 0 Q6ZS81 WDFY4_HUMAN WD repeat- and FYVE domain-containing protein 4 WDFY4 C10orf64 KIAA1607 Homo sapiens (Human) "antigen processing and presentation [GO:0019882]; autophagy [GO:0006914]; CD8-positive, alpha-beta T cell activation [GO:0036037]; cellular response to virus [GO:0098586]" early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783] 0.96933 -3.3876 DSLDAMLQWLLQR 0 9.46536 0 0 11.546 0 0 0 12.0754 0 0 0 0 0 0 8.79539 0 0 8.96783 0 0 11.6631 0 0 0 0 8.68106 Q6ZS82 R9BP_HUMAN Regulator of G-protein signaling 9-binding protein (RGS9-anchoring protein) RGS9BP R9AP Homo sapiens (Human) detection of light stimulus involved in visual perception [GO:0050908]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968] membrane [GO:0016020]; neuron projection [GO:0043005] 0.77656 0.26457 TGVAGASSGVAAR 0 0 9.1185 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.77038 0 0 0 0 Q6ZS86 GLPK5_HUMAN Putative glycerol kinase 5 (GK 5) (Glycerokinase 5) (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase 5) GK5 Homo sapiens (Human) glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate biosynthetic process [GO:0046167]; phosphorylation [GO:0016310]; triglyceride metabolic process [GO:0006641] mitochondrion [GO:0005739] ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370] 0.96147 -2.5603 ADGGVCK 0 0 0 0 0 0 0 0 0 0 8.93455 8.18294 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZS92 YD022_HUMAN Putative uncharacterized protein FLJ45721 Homo sapiens (Human) 0.95469 -1.5198 YCREGSVIGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.29751 0 0 0 0 0 0 0 0 Q6ZSA8 YS025_HUMAN Putative uncharacterized protein FLJ45684 Homo sapiens (Human) 0.87938 0.018379 LPPSALHHTLHCVPR 0 0 0 0 0 9.55555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZSB9 ZBT49_HUMAN Zinc finger and BTB domain-containing protein 49 (Zinc finger protein 509) ZBTB49 ZNF509 Homo sapiens (Human) cell cycle [GO:0007049]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of cytokine production [GO:0001817]; regulation of immune system process [GO:0002682] cytoplasm [GO:0005737]; cytosol [GO:0005829]; microtubule cytoskeleton [GO:0015630]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA-binding transcription factor binding [GO:0140297]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription coactivator binding [GO:0001223] 0.9697 -4.6996 KLNFLKSQK 0 0 0 0 0 0 0 0 0 9.20596 11.5767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZSC3 RBM43_HUMAN RNA-binding protein 43 (RNA-binding motif protein 43) RBM43 C2orf38 Homo sapiens (Human) RNA binding [GO:0003723] 0.9219 -1.0865 ACEQLSSR 0 8.59526 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0934 0 0 0 0 0 0 0 0 0 0 Q6ZSG1 ARK2C_HUMAN E3 ubiquitin-protein ligase ARK2C (EC 2.3.2.27) (RING finger protein 165) (RNF165) ARK2C RNF165 Homo sapiens (Human) forelimb morphogenesis [GO:0035136]; innervation [GO:0060384]; motor neuron axon guidance [GO:0008045]; muscle structure development [GO:0061061]; positive regulation of BMP signaling pathway [GO:0030513]; protein catabolic process [GO:0030163]; protein polyubiquitination [GO:0000209] nucleus [GO:0005634]; protein-containing complex [GO:0032991] ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.81167 0.22413 GAVQNTIER 0 9.22381 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.895 0 Q6ZSI9 CAN12_HUMAN Calpain-12 (EC 3.4.22.-) (Calcium-activated neutral proteinase 12) (CANP 12) CAPN12 Homo sapiens (Human) proteolysis [GO:0006508] cytoplasm [GO:0005737] calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198] 0.91547 -0.76336 KEDGEFWMELR 0 0 0 0 0 0 10.4808 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZSM3 MOT12_HUMAN Monocarboxylate transporter 12 (MCT 12) (Creatine transporter 2) (CRT2) (Solute carrier family 16 member 12) SLC16A12 MCT12 Homo sapiens (Human) creatine transmembrane transport [GO:0015881]; creatinine metabolic process [GO:0046449]; monocarboxylic acid transport [GO:0015718]; transport across blood-brain barrier [GO:0150104] basolateral plasma membrane [GO:0016323]; plasma membrane [GO:0005886] creatine transmembrane transporter activity [GO:0005308]; monocarboxylic acid transmembrane transporter activity [GO:0008028]; uniporter activity [GO:0015292] 0.93391 -1.2897 KTMAKVNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.6115 0 0 0 0 0 0 0 0 0 0 Q6ZSN1 YI023_HUMAN Putative uncharacterized protein FLJ45355 Homo sapiens (Human) 0.8839 -0.10915 CLHPFRWGSQDRGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2685 0 Q6ZSR9 YJ005_HUMAN Uncharacterized protein FLJ45252 Homo sapiens (Human) 0.84866 0.15532 IVSQTNK 10.3301 10.0386 10.0992 0 0 0 10.1722 0 0 0 11.0898 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZSS3 ZN621_HUMAN Zinc finger protein 621 ZNF621 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.9322 -1.2607 CKECWKAFGCR 0 0 0 0 0 0 0 0 0 0 0 10.7768 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZST4 LCNL1_HUMAN Lipocalin-like 1 protein LCNL1 Homo sapiens (Human) small molecule binding [GO:0036094] 0.76117 0.29595 MAVVLVTPLGNGDLALK 15.6648 15.4871 15.4233 13.2587 13.4602 13.4497 14.9258 15.1523 15.2166 15.2445 15.1781 15.3134 14.0663 14.0697 14.1699 14.9726 15.0677 0 0 0 11.7677 0 0 0 0 0 0 Q6ZSZ5 ARHGI_HUMAN Rho guanine nucleotide exchange factor 18 (114 kDa Rho-specific guanine nucleotide exchange factor) (p114-Rho-GEF) (p114RhoGEF) (Septin-associated RhoGEF) (SA-RhoGEF) ARHGEF18 KIAA0521 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; negative regulation of stress fiber assembly [GO:0051497]; protein localization to cell-cell junction [GO:0150105]; regulation of cell shape [GO:0008360]; regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264] apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] guanyl-nucleotide exchange factor activity [GO:0005085]; metal ion binding [GO:0046872] 0.96965 -4.9826 DSAPTENRLAK 0 0 0 0 8.61021 0 0 0 9.13443 0 0 0 0 0 10.8347 0 0 11.6064 9.56786 0 0 0 0 0 9.53924 0 0 Q6ZSZ6 TSH1_HUMAN Teashirt homolog 1 (Antigen NY-CO-33) (Serologically defined colon cancer antigen 33) TSHZ1 SDCCAG33 TSH1 Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; middle ear morphogenesis [GO:0042474]; regulation of transcription by RNA polymerase II [GO:0006357]; soft palate development [GO:0060023] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]" 0.61238 0.42596 EGPLDVHTPNGTEPLK 0 0 10.1396 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZT07 TBCD9_HUMAN TBC1 domain family member 9 (TBC1 domain family member 9A) TBC1D9 KIAA0882 TBC1D9A Homo sapiens (Human) activation of GTPase activity [GO:0090630] calcium ion binding [GO:0005509]; GTPase activator activity [GO:0005096] 0.96559 -2.3661 EFLKEQAWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.44995 0 0 0 0 Q6ZT21 TMPPE_HUMAN Transmembrane protein with metallophosphoesterase domain (EC 3.1.-.-) TMPPE Homo sapiens (Human) membrane [GO:0016020] hydrolase activity [GO:0016787]; metal ion binding [GO:0046872] 0.87052 0.03865 IVLLSDIHLGPTVGR 9.2391 0 0 0 0 0 0 10.295 0 0 0 0 0 0 0 0 0 0 9.35147 0 0 0 0 0 0 0 0 Q6ZT89 S2548_HUMAN Solute carrier family 25 member 48 SLC25A48 Homo sapiens (Human) mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] transmembrane transporter activity [GO:0022857] 0.95444 -1.5152 VFFRGITVNAVR 0 0 0 0 0 0 0 0 0 0 11.2108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZT98 TTLL7_HUMAN Tubulin polyglutamylase TTLL7 (EC 6.3.2.-) (Testis development protein NYD-SP30) (Tubulin--tyrosine ligase-like protein 7) TTLL7 Homo sapiens (Human) cell differentiation [GO:0030154]; microtubule cytoskeleton organization [GO:0000226]; nervous system development [GO:0007399]; protein polyglutamylation [GO:0018095] cilium [GO:0005929]; cytosol [GO:0005829]; dendrite [GO:0030425]; microtubule [GO:0005874]; perikaryon [GO:0043204] alpha-tubulin binding [GO:0043014]; ATP binding [GO:0005524]; beta-tubulin binding [GO:0048487]; metal ion binding [GO:0046872]; tubulin binding [GO:0015631]; tubulin-glutamic acid ligase activity [GO:0070740] 0.90701 -0.71228 LKPWLLEINR 0 0 0 0 0 0 0 0 0 0 0 0 11.8237 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZTA4 TRI67_HUMAN Tripartite motif-containing protein 67 (TRIM9-like protein) TRIM67 TNL Homo sapiens (Human) negative regulation of Ras protein signal transduction [GO:0046580]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; regulation of protein localization [GO:0032880] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856] zinc ion binding [GO:0008270] 0.94764 -1.3663 AWAMYVDNNR 0 0 0 0 0 0 0 0 0 9.82485 11.2423 9.3388 0 0 0 0 0 0 0 0 0 0 9.91355 0 0 0 0 Q6ZTI0 YK032_HUMAN Putative uncharacterized protein FLJ44636 Homo sapiens (Human) 0.67665 0.39371 GSGGSAR 8.60433 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZTN6 AN13D_HUMAN Ankyrin repeat domain-containing protein 13D ANKRD13D Homo sapiens (Human) negative regulation of receptor internalization [GO:0002091] cytoplasm [GO:0005737]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] ubiquitin-dependent protein binding [GO:0140036] 0.92315 -1.0607 DYQRATQR 0 0 0 8.86242 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.46974 10.2718 9.69125 0 Q6ZTQ3 RASF6_HUMAN Ras association domain-containing protein 6 RASSF6 Homo sapiens (Human) apoptotic process [GO:0006915]; signal transduction [GO:0007165] 0.93325 -1.2882 NARIFLMDK 0 0 0 0 0 0 0 0 0 0 12.4253 0 0 0 9.46657 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZTQ4 CDHR3_HUMAN Cadherin-related family member 3 (Cadherin-like protein 28) CDHR3 CDH28 Homo sapiens (Human) "adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; synaptic transmission, glutamatergic [GO:0035249]" adherens junction [GO:0005912]; axon terminus [GO:0043679]; catenin complex [GO:0016342]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083] cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; virus receptor activity [GO:0001618] 0.88368 -0.32765 EPLTKKGETK 0 0 10.8143 0 0 0 0 0 0 8.59048 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZTR5 CFA47_HUMAN Cilia- and flagella-associated protein 47 CFAP47 CHDC2 CXorf22 CXorf30 CXorf59 Homo sapiens (Human) cilium assembly [GO:0060271]; sperm axoneme assembly [GO:0007288] cilium [GO:0005929]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; sperm connecting piece [GO:0097224] 0.79778 0.24311 ADHQACINFYCTQFTEWK 11.4001 0 10.5152 10.6245 12.3819 11.4841 11.4114 9.83682 9.80793 13.1865 0 11.6245 0 0 0 0 11.6537 0 0 0 0 0 0 0 9.65319 0 0 Q6ZTU2 E400N_HUMAN Putative EP400-like protein (EP400 pseudogene 1) EP400P1 EP400NL Homo sapiens (Human) 0.81562 0.22134 LYGPLQAYLR 0 0 0 9.64938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZTZ1 MSD1_HUMAN Myb/SANT-like DNA-binding domain-containing protein 1 MSANTD1 C4orf44 Homo sapiens (Human) positive regulation of DNA-templated transcription [GO:0045893] nuclear body [GO:0016604] 0.8058 0.23511 LLEAMVEEQR 0 0 0 0 9.13175 0 0 0 0 0 0 0 0 0 0 0 12.5474 0 0 0 0 0 0 0 0 0 0 Q6ZU15 SEP14_HUMAN Septin-14 SEPTIN14 SEPT14 Homo sapiens (Human) cytoskeleton-dependent cytokinesis [GO:0061640]; neuron migration [GO:0001764]; protein localization to perinuclear region of cytoplasm [GO:1905719]; spermatid development [GO:0007286] acrosomal vesicle [GO:0001669]; axon [GO:0030424]; cell division site [GO:0032153]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dendrite [GO:0030425]; microtubule cytoskeleton [GO:0015630]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; septin complex [GO:0031105]; septin ring [GO:0005940] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; molecular adaptor activity [GO:0060090] 0.95967 -1.8231 NDLQTFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.09627 0 8.97106 Q6ZU35 CRACD_HUMAN Capping protein-inhibiting regulator of actin dynamics (Cancer-related regulator of actin dynamics) CRACD CRAD KIAA1211 Homo sapiens (Human) epithelial structure maintenance [GO:0010669]; maintenance of gastrointestinal epithelium [GO:0030277]; negative regulation of barbed-end actin filament capping [GO:2000813]; positive regulation of actin filament polymerization [GO:0030838] cytosol [GO:0005829] 0.42162 0.66978 LQAQAQAEERR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0933 0 0 0 0 0 9.24653 0 0 0 Q6ZU64 CFA65_HUMAN Cilia- and flagella-associated protein 65 (Coiled-coil domain-containing protein 108) CFAP65 CCDC108 Homo sapiens (Human) flagellated sperm motility [GO:0030317]; sperm axoneme assembly [GO:0007288] acrosomal membrane [GO:0002080]; acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; sperm flagellum [GO:0036126]; sperm midpiece [GO:0097225] RNA binding [GO:0003723] 0.93325 -1.2839 EEQEQDEKEAIR 0 0 0 0 0 0 0 0 0 0 0 11.645 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZU65 UBN2_HUMAN Ubinuclein-2 UBN2 KIAA2030 Homo sapiens (Human) extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.95946 -1.9494 CAKLQTDEEREK 0 0 10.2229 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZU69 S31F1_HUMAN Protein SPATA31F1 (Protein FAM205A) SPATA31F1 C9orf144B FAM205A Homo sapiens (Human) membrane [GO:0016020]; nucleus [GO:0005634] 0.95424 -1.5159 CGQIHQGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.677 0 0 0 0 0 0 0 10.5215 9.7057 0 0 Q6ZU80 CE128_HUMAN Centrosomal protein of 128 kDa (Cep128) CEP128 C14orf145 C14orf61 Homo sapiens (Human) protein localization [GO:0008104] centriolar subdistal appendage [GO:0120103]; centriole [GO:0005814]; centrosome [GO:0005813]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; spindle pole [GO:0000922] 0.96832 -8.8583 ALEKQSETVDELTGK 10.3898 0 13.1896 11.7142 0 0 0 0 10.2907 0 0 0 0 11.1424 0 0 0 0 0 0 9.47208 0 0 10.0438 0 0 0 Q6ZUA9 MROH5_HUMAN Maestro heat-like repeat family member 5 MROH5 Homo sapiens (Human) cytoplasm [GO:0005737] 0.63125 0.40735 LALENMTK 0 0 0 0 0 8.33307 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.09075 0 0 Q6ZUB0 S31D4_HUMAN Spermatogenesis-associated protein 31D4 (Protein FAM75D4) SPATA31D4 FAM75D4 Homo sapiens (Human) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] membrane [GO:0016020] 0.95187 -1.3838 FEEINEGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.71239 0 0 0 0 0 0 0 0 0 0 Q6ZUB1 S31E1_HUMAN Spermatogenesis-associated protein 31E1 (Protein FAM75E1) SPATA31E1 C9orf79 FAM75E1 Homo sapiens (Human) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] membrane [GO:0016020] 0.92735 -1.2176 ADHPHMTSLGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.85714 0 0 0 0 0 0 0 0 10.9431 0 0 Q6ZUG5 YC006_HUMAN Uncharacterized protein FLJ43738 Homo sapiens (Human) 0.82947 0.20875 IIFVFDFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.21604 0 0 0 0 0 10.0541 0 0 0 Q6ZUI0 TPRG1_HUMAN Tumor protein p63-regulated gene 1 protein (Protein FAM79B) TPRG1 FAM79B Homo sapiens (Human) cytoplasm [GO:0005737] 0.96115 -2.5603 LSGFMSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.96264 0 0 0 0 Q6ZUJ8 BCAP_HUMAN Phosphoinositide 3-kinase adapter protein 1 (B-cell adapter for phosphoinositide 3-kinase) (B-cell phosphoinositide 3-kinase adapter protein 1) PIK3AP1 BCAP Homo sapiens (Human) positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of inflammatory response [GO:0050727]; toll-like receptor 2 signaling pathway [GO:0034134]; toll-like receptor 4 signaling pathway [GO:0034142]; toll-like receptor 7 signaling pathway [GO:0034154]; toll-like receptor 9 signaling pathway [GO:0034162] cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886] identical protein binding [GO:0042802]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; signaling receptor binding [GO:0005102] 0.96774 -2.3454 AASGVPR 0 0 0 0 0 0 0 0 0 15.215 8.32957 9.63023 0 0 0 0 0 0 0 0 0 0 0 0 0 14.9557 0 Q6ZUL3 CH086_HUMAN Uncharacterized protein LINC03042 (Long intergenic non-protein coding RNA 3042) LINC03042 C8orf86 Homo sapiens (Human) 0.968 -3.7246 GLLPAEELIRSNLGVGR 9.46483 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9238 9.53101 0 0 0 0 Q6ZUM4 RHG27_HUMAN Rho GTPase-activating protein 27 (CIN85-associated multi-domain-containing Rho GTPase-activating protein 1) (Rho-type GTPase-activating protein 27) (SH3 domain-containing protein 20) ARHGAP27 CAMGAP1 SH3D20 PP905 Homo sapiens (Human) positive regulation of GTPase activity [GO:0043547]; receptor-mediated endocytosis [GO:0006898]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020] GTPase activator activity [GO:0005096]; SH3 domain binding [GO:0017124] 0.91539 -0.7936 VDFGSSERLGSWQEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.30868 0 0 0 0 0 0 0 Q6ZUS5 CC121_HUMAN Coiled-coil domain-containing protein 121 CCDC121 Homo sapiens (Human) 0.76059 0.29371 LQGSHNQCLNRQDVPK 0 0 0 0 0 0 0 0 0 0 0 0 14.8411 10.6662 0 0 0 10.9546 0 0 0 0 0 0 0 0 0 Q6ZUS6 CC149_HUMAN Coiled-coil domain-containing protein 149 CCDC149 Homo sapiens (Human) 0.96227 -2.5431 EERSSYQDK 0 0 0 0 0 0 0 0 0 0 0 10.8682 0 0 0 0 0 0 0 0 0 0 0 0 0 8.58124 0 Q6ZUT3 FRMD7_HUMAN FERM domain-containing protein 7 FRMD7 Homo sapiens (Human) negative regulation of protein binding [GO:0032091]; negative regulation of stress fiber assembly [GO:0051497]; nervous system development [GO:0007399]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; regulation of neuron projection development [GO:0010975] cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] guanyl-nucleotide exchange factor activity [GO:0005085] 0.90655 -0.71842 EELTRYLFTLQIKK 0 0 0 0 9.44555 0 0 0 0 0 0 0 0 9.9455 0 0 0 0 0 10.541 0 0 10.4801 0 0 0 0 Q6ZUT6 CCD9B_HUMAN Coiled-coil domain-containing protein 9B CCDC9B C15orf52 Homo sapiens (Human) RNA binding [GO:0003723] 0.78655 0.25734 GAGLPEPGEDR 0 0 0 0 0 0 0 0 0 0 0 0 9.87981 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZUX3 TGRM2_HUMAN TOG array regulator of axonemal microtubules protein 2 (Crescerin-2) TOGARAM2 FAM179A Homo sapiens (Human) microtubule cytoskeleton organization [GO:0000226]; regulation of cellular component organization [GO:0051128] cilium [GO:0005929]; cytoplasmic microtubule [GO:0005881] microtubule binding [GO:0008017] 0.96934 -3.5932 ELTRLLEAKDFR 0 0 0 0 12.2156 0 10.3866 10.4056 0 0 0 0 8.82547 9.50785 0 0 0 0 0 0 9.67774 0 0 0 0 0 0 Q6ZUX7 LHPL2_HUMAN LHFPL tetraspan subfamily member 2 protein (Lipoma HMGIC fusion partner-like 2 protein) LHFPL2 KIAA0206 Homo sapiens (Human) development of primary female sexual characteristics [GO:0046545]; development of primary male sexual characteristics [GO:0046546]; positive regulation of fertilization [GO:1905516]; single fertilization [GO:0007338] membrane [GO:0016020]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092] 0.82954 0.20763 MCHVIVTCR 0 0 0 0 0 0 0 0 0 9.78139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZV29 PLPL7_HUMAN Patatin-like phospholipase domain-containing protein 7 (EC 3.1.1.-) (EC 3.1.1.5) PNPLA7 C9orf111 Homo sapiens (Human) phosphatidylcholine catabolic process [GO:0034638] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; lipid droplet [GO:0005811] lysophospholipase activity [GO:0004622]; phosphatidyl phospholipase B activity [GO:0102545] 0.94011 -1.3005 ARVFLHSDEHPGSSVASKSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1392 Q6ZV60 YL023_HUMAN Putative uncharacterized protein encoded by LINC00173 LINC00173 NCRNA00173 Homo sapiens (Human) 0.9471 -1.3531 GVCQGWHCVKKWACK 0 0 0 0 0 0 0 9.88623 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZV65 FA47E_HUMAN Protein FAM47E FAM47E Homo sapiens (Human) positive regulation of histone methylation [GO:0031062]; protein localization to chromatin [GO:0071168]; transcription initiation-coupled chromatin remodeling [GO:0045815] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleus [GO:0005634] enzyme activator activity [GO:0008047] 0.34465 0.77006 EPTKLLK 0 0 0 0 0 0 0 0 0 9.49651 9.48259 9.51757 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZV70 LANC3_HUMAN LanC-like protein 3 LANCL3 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; peptide modification [GO:0031179] plasma membrane [GO:0005886] 0.94361 -1.3383 YIYRAQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.91437 0 9.32414 0 0 0 0 0 0 Q6ZV73 FGD6_HUMAN "FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24)" FGD6 KIAA1362 ZFYVE24 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cytoskeleton organization [GO:0007010]; filopodium assembly [GO:0046847]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; Golgi apparatus [GO:0005794]; lamellipodium [GO:0030027]; ruffle [GO:0001726] guanyl-nucleotide exchange factor activity [GO:0005085]; metal ion binding [GO:0046872]; small GTPase binding [GO:0031267] 0.97023 -4.3236 AASEELLEK 9.09231 8.78735 0 0 0 0 0 10.2803 0 0 0 11.6777 9.67707 9.85706 8.61842 10.3623 9.82869 0 0 0 0 0 0 0 0 0 0 Q6ZVD8 PHLP2_HUMAN PH domain leucine-rich repeat-containing protein phosphatase 2 (EC 3.1.3.16) (PH domain leucine-rich repeat-containing protein phosphatase-like) (PHLPP-like) PHLPP2 KIAA0931 PHLPPL Homo sapiens (Human) hippocampus development [GO:0021766]; protein dephosphorylation [GO:0006470] cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; intracellular membrane-bounded organelle [GO:0043231]; mitotic spindle [GO:0072686]; nucleoplasm [GO:0005654]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment membrane [GO:0042622] metal ion binding [GO:0046872]; myosin phosphatase activity [GO:0017018]; protein serine/threonine phosphatase activity [GO:0004722] 0.96958 -3.5215 EQMKQHQDSR 0 0 0 11.6542 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.61397 Q6ZVH6 YK004_HUMAN Putative uncharacterized protein FLJ42569 Homo sapiens (Human) 0.82497 0.2126 HGAPNPAQSHLHVQAR 0 0 0 0 0 9.08058 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZVH7 ESPNL_HUMAN Espin-like protein ESPNL Homo sapiens (Human) actin filament bundle assembly [GO:0051017]; sensory perception of sound [GO:0007605] cytoplasm [GO:0005737]; stereocilium tip [GO:0032426] actin filament binding [GO:0051015] 0.88132 -0.3073 EQMTSPAPPR 0 0 0 0 0 0 0 0 0 0 0 0 9.85471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZVL6 K154L_HUMAN UPF0606 protein KIAA1549L KIAA1549L C11orf41 C11orf69 Homo sapiens (Human) membrane [GO:0016020] 0.96979 -4.1619 LAQLFMMSQQQGR 0 0 0 0 0 0 0 0 0 0 0 10.274 0 10.1268 0 0 0 0 9.79237 9.50289 0 0 0 0 0 0 11.7049 Q6ZVT6 CF20D_HUMAN Protein CFAP20DC (Uncharacterized protein C3orf67) CFAP20DC C3orf67 Homo sapiens (Human) 0.96007 -1.9789 LRLKSTSR 0 0 0 0 0 0 0 9.65327 0 0 0 15.891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZVW7 I17EL_HUMAN Putative interleukin-17 receptor E-like (IL-17 receptor E-like) (IL-17RE-like) IL17REL Homo sapiens (Human) interleukin-17 receptor activity [GO:0030368] 0.8484 0.15608 LSYWVDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.44346 0 0 Q6ZVZ8 ASB18_HUMAN Ankyrin repeat and SOCS box protein 18 (ASB-18) ASB18 Homo sapiens (Human) intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567] cytosol [GO:0005829] 0.96961 -4.0831 GAHVDAR 0 0 0 0 0 0 0 0 0 0 0 8.43288 0 0 0 0 0 0 0 0 0 0 0 0 10.1594 0 0 Q6ZW13 CP086_HUMAN Uncharacterized protein C16orf86 C16orf86 Homo sapiens (Human) 0.882 0.01071 GTQSEDQRPAGAASESELQEEGPK 0 10.2119 0 0 0 10.2621 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZW31 SYDE1_HUMAN Rho GTPase-activating protein SYDE1 (Synapse defective protein 1 homolog 1) (Protein syd-1 homolog 1) SYDE1 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; activation of GTPase activity [GO:0090630]; cell migration [GO:0016477]; positive regulation of trophoblast cell migration [GO:1901165]; regulation of cytoskeleton organization [GO:0051493]; regulation of Ras protein signal transduction [GO:0046578]; signal transduction [GO:0007165] synaptic membrane [GO:0097060] GTPase activator activity [GO:0005096]; GTPase regulator activity [GO:0030695] 0.91323 -0.76236 YHLDSSVGGPGPAAGPGGTRSPR 0 0 0 0 0 0 0 0 0 0 9.68536 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZW49 PAXI1_HUMAN PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein) PAXIP1 PAXIP1L PTIP CAGF28 Homo sapiens (Human) "adipose tissue development [GO:0060612]; chorion development [GO:0060717]; chromatin remodeling [GO:0006338]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; endothelial cell migration [GO:0043542]; histone H3-K4 methylation [GO:0051568]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of isotype switching [GO:0045830]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; regulation of cell cycle G2/M phase transition [GO:1902749]; response to ionizing radiation [GO:0010212]; vasculogenesis [GO:0001570]" chromosome [GO:0005694]; histone methyltransferase complex [GO:0035097]; MLL3/4 complex [GO:0044666]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.052192 1.4071 AIVECAGGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1186 0 0 0 0 0 10.6701 0 0 0 10.5401 0 Q6ZW61 BBS12_HUMAN Bardet-Biedl syndrome 12 protein BBS12 C4orf24 Homo sapiens (Human) chaperone-mediated protein complex assembly [GO:0051131]; eating behavior [GO:0042755]; fat cell differentiation [GO:0045444]; intraciliary transport [GO:0042073]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of stem cell differentiation [GO:2000737]; photoreceptor cell maintenance [GO:0045494]; stem cell differentiation [GO:0048863] cilium [GO:0005929] ATP binding [GO:0005524] 0.56664 0.50218 SSPLDVVDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.89341 0 0 0 Q6ZW76 ANKS3_HUMAN Ankyrin repeat and SAM domain-containing protein 3 ANKS3 KIAA1977 Homo sapiens (Human) cilium [GO:0005929]; cytoplasm [GO:0005737] 0.95491 -1.5691 SLYRSPEK 0 10.0063 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZWB6 KCTD8_HUMAN BTB/POZ domain-containing protein KCTD8 KCTD8 Homo sapiens (Human) protein homooligomerization [GO:0051260]; regulation of G protein-coupled receptor signaling pathway [GO:0008277] cell projection [GO:0042995]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235] 0.72852 0.33347 RGELPRDSR 0 0 0 0 0 0 0 0 0 0 0 0 9.65503 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q6ZWH5 NEK10_HUMAN Serine/threonine-protein kinase Nek10 (EC 2.7.11.1) (Never in mitosis A-related kinase 10) (NimA-related protein kinase 10) NEK10 Homo sapiens (Human) mucociliary clearance [GO:0120197]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein autophosphorylation [GO:0031954]; protein phosphorylation [GO:0006468]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of ERK1 and ERK2 cascade [GO:0070372] extracellular region [GO:0005576]; protein kinase complex [GO:1902911] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96945 -4.5712 ESTFNILKRSFSASGGER 0 0 0 0 0 0 0 0 12.4884 0 0 0 0 0 0 0 10.8334 11.8648 0 0 0 11.5896 11.0373 0 0 0 0 Q6ZWI9 RFPLB_HUMAN Ret finger protein-like 4B (RING finger protein 211) RFPL4B RNF211 Homo sapiens (Human) protein ubiquitination [GO:0016567]; regulation of gene expression [GO:0010468] cytoplasm [GO:0005737] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630] 0.61004 0.42996 AGAIHANTHLER 0 0 0 0 0 0 0 0 0 0 0 0 9.92813 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q702N8 XIRP1_HUMAN Xin actin-binding repeat-containing protein 1 (Cardiomyopathy-associated protein 1) XIRP1 CMYA1 XIN Homo sapiens (Human) actin filament organization [GO:0007015]; negative regulation of protein binding [GO:0032091] anchoring junction [GO:0070161] actin filament binding [GO:0051015]; RNA binding [GO:0003723] 0.96191 -2.61 ELEATVR 0 0 0 0 0 0 0 0 0 11.1909 9.07818 0 0 0 0 0 0 0 0 0 0 0 0 10.7366 0 0 0 Q709C8 VP13C_HUMAN Intermembrane lipid transfer protein VPS13C (Vacuolar protein sorting-associated protein 13C) VPS13C KIAA1421 Homo sapiens (Human) Golgi to endosome transport [GO:0006895]; lipid transport [GO:0006869]; mitochondrion organization [GO:0007005]; negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:1905090]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; response to insulin [GO:0032868] cytoplasm [GO:0005737]; cytosol [GO:0005829]; dense core granule membrane [GO:0032127]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lipid droplet [GO:0005811]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; mitochondrial outer membrane [GO:0005741] 0.96938 -7.4114 ENALSELDVPFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5269 0 0 0 10.0287 9.95646 0 10.7166 0 Q709F0 ACD11_HUMAN Acyl-CoA dehydrogenase family member 11 (ACAD-11) (EC 1.3.8.-) ACAD11 Homo sapiens (Human) fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539] cytoplasm [GO:0005737]; mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; peroxisome [GO:0005777] acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; long-chain-acyl-CoA dehydrogenase activity [GO:0004466]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]; very-long-chain-acyl-CoA dehydrogenase activity [GO:0017099] 0.94844 -1.3617 GFEISQGRLGPGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.85845 9.52025 0 0 0 0 10.0572 0 0 0 0 0 Q70CQ1 UBP49_HUMAN Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.4.19.12) (Deubiquitinating enzyme 49) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) USP49 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]" cytoplasm [GO:0005737]; nucleoplasm [GO:0005654] cysteine-type deubiquitinase activity [GO:0004843]; cysteine-type endopeptidase activity [GO:0004197]; histone binding [GO:0042393]; histone H2B deubiquitinase activity [GO:0140936]; zinc ion binding [GO:0008270] 0.94826 -1.3645 ILIPFSQR 0 0 0 0 0 0 0 0 0 9.40075 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q70CQ2 UBP34_HUMAN Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.4.19.12) (Deubiquitinating enzyme 34) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) USP34 KIAA0570 KIAA0729 Homo sapiens (Human) positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055] cytosol [GO:0005829]; nucleus [GO:0005634] cysteine-type deubiquitinase activity [GO:0004843]; cysteine-type endopeptidase activity [GO:0004197] 0.97003 -5.2593 AAGDHAK 0 9.69566 11.9287 0 11.4471 8.72291 0 0 12.7163 9.42968 0 8.62917 0 0 0 0 0 0 0 0 0 10.3167 0 0 0 11.2604 0 Q70CQ3 UBP30_HUMAN Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.4.19.12) (Deubiquitinating enzyme 30) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Ub-specific protease 30) USP30 Homo sapiens (Human) autophagy of mitochondrion [GO:0000422]; mitochondrial fusion [GO:0008053]; negative regulation of mitophagy [GO:1901525]; pexophagy [GO:0000425]; protein deubiquitination [GO:0016579]; protein K11-linked deubiquitination [GO:0035871]; protein K6-linked deubiquitination [GO:0044313]; ubiquitin-dependent protein catabolic process [GO:0006511] cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; peroxisomal membrane [GO:0005778] cysteine-type deubiquitinase activity [GO:0004843]; cysteine-type endopeptidase activity [GO:0004197]; deubiquitinase activity [GO:0101005] 0.96803 -3.6612 GTLNGEKVEHQRTTFVK 10.9346 0 0 0 0 0 0 0 0 0 9.47942 0 0 0 0 0 0 11.7578 0 0 0 0 0 0 0 0 0 Q70CQ4 UBP31_HUMAN Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.4.19.12) (Deubiquitinating enzyme 31) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) USP31 KIAA1203 Homo sapiens (Human) protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] nucleus [GO:0005634] cysteine-type deubiquitinase activity [GO:0004843] 0.96726 -2.8252 KPESTTK 0 0 0 0 0 0 0 12.1767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.26639 0 10.3769 0 0 Q70E73 RAPH1_HUMAN Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) RAPH1 ALS2CR18 ALS2CR9 KIAA1681 LPD PREL2 RMO1 Homo sapiens (Human) axon extension [GO:0048675]; signal transduction [GO:0007165] cytoskeleton [GO:0005856]; cytosol [GO:0005829]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; nuclear body [GO:0016604]; plasma membrane [GO:0005886] 0.96288 -2.1755 DLVCFLQLDHVNVYYGQDYR 0 10.1392 0 0 0 0 0 9.668 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.79273 0 0 0 Q70EK8 UBP53_HUMAN Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin-specific peptidase 53) USP53 KIAA1350 Homo sapiens (Human) action potential [GO:0001508]; epithelial cell apoptotic process [GO:1904019]; outer hair cell apoptotic process [GO:1905584]; protein deubiquitination [GO:0016579]; response to auditory stimulus [GO:0010996]; sensory perception of sound [GO:0007605] bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911] 0.96956 -3.441 DLEKGQRK 0 0 0 9.68435 0 0 10.1746 0 0 0 0 0 0 0 0 0 0 0 9.96209 0 0 0 0 0 0 0 0 Q70EL1 UBP54_HUMAN Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin-specific peptidase 54) USP54 C10orf29 Homo sapiens (Human) protein deubiquitination [GO:0016579] cysteine-type deubiquitinase activity [GO:0004843] 0.96724 -3.7808 EFIPDEPSKPPSYDIK 0 0 9.27687 0 0 0 0 0 0 12.694 0 0 0 0 0 0 0 0 0 0 9.33938 0 0 0 0 0 0 Q70EL2 UBP45_HUMAN Ubiquitin carboxyl-terminal hydrolase 45 (EC 3.4.19.12) (Deubiquitinating enzyme 45) (Ubiquitin thioesterase 45) (Ubiquitin-specific-processing protease 45) USP45 Homo sapiens (Human) cell migration [GO:0016477]; DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; neural retina development [GO:0003407]; photoreceptor cell maintenance [GO:0045494]; protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; photoreceptor inner segment [GO:0001917] cysteine-type deubiquitinase activity [GO:0004843]; zinc ion binding [GO:0008270] 0.20821 0.90988 ALSAQAYLLFYER 0 0 0 0 0 9.33983 12.6571 0 0 0 0 0 0 11.8071 0 0 0 0 0 0 9.47123 0 0 10.2334 0 0 0 Q70EL4 UBP43_HUMAN Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.4.19.12) (Deubiquitinating enzyme 43) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) USP43 Homo sapiens (Human) protein deubiquitination [GO:0016579]; translesion synthesis [GO:0019985]; ubiquitin-dependent protein catabolic process [GO:0006511] nucleoplasm [GO:0005654] cysteine-type deubiquitinase activity [GO:0004843]; ISG15-specific peptidase activity [GO:0019785] 0.91975 -0.89202 ASRAPRGSALGMSQR 0 0 0 0 0 0 0 0 0 0 0 11.3106 0 8.75649 10.9799 0 0 0 0 0 0 10.8467 0 10.7393 0 0 0 Q70HW3 SAMC_HUMAN Mitochondrial S-adenosylmethionine carrier protein (SAM carrier) (Solute carrier family 25 member 26) SLC25A26 SAMC Homo sapiens (Human) macromolecule methylation [GO:0043414]; mitochondrial S-adenosyl-L-methionine transmembrane transport [GO:1990543]; monoatomic ion transport [GO:0006811]; S-adenosyl-L-methionine transport [GO:0015805] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] S-adenosyl-L-methionine transmembrane transporter activity [GO:0000095]; S-adenosyl-L-methionine:S-adenosyl-L-homocysteine antiporter activity [GO:0180003] 0.95434 -1.5153 VPSEVVKQR 0 0 0 0 0 0 0 0 11.7874 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q70IA8 MOB3C_HUMAN MOB kinase activator 3C (Mob1 homolog 2C) (Mps one binder kinase activator-like 2C) MOB3C MOBKL2C Homo sapiens (Human) positive regulation of protein phosphorylation [GO:0001934]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; nucleus [GO:0005634] metal ion binding [GO:0046872]; protein kinase activator activity [GO:0030295] 0.43469 0.65509 EFSLVDQR 0 0 0 0 0 0 13.4705 13.7041 0 0 0 0 12.9487 0 0 0 0 0 12.4569 0 0 11.6927 0 9.83654 0 0 0 Q70J99 UN13D_HUMAN Protein unc-13 homolog D (Munc13-4) UNC13D Homo sapiens (Human) defense response to virus [GO:0051607]; germinal center formation [GO:0002467]; granuloma formation [GO:0002432]; natural killer cell degranulation [GO:0043320]; phagocytosis [GO:0006909]; positive regulation of exocytosis [GO:0045921]; positive regulation of regulated secretory pathway [GO:1903307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of mast cell degranulation [GO:0043304]; secretion [GO:0046903] azurophil granule lumen [GO:0035578]; cytosol [GO:0005829]; exocytic vesicle [GO:0070382]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; recycling endosome [GO:0055037]; Weibel-Palade body [GO:0033093] metal ion binding [GO:0046872]; small GTPase binding [GO:0031267] 0.95594 -1.6425 ASYRASEQK 0 0 0 0 0 0 0 0 0 0 8.78418 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q70SY1 CR3L2_HUMAN Cyclic AMP-responsive element-binding protein 3-like protein 2 (cAMP-responsive element-binding protein 3-like protein 2) (BBF2 human homolog on chromosome 7) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 2] CREB3L2 BBF2H7 Homo sapiens (Human) cartilage development [GO:0051216]; chondrocyte differentiation [GO:0002062]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron projection development [GO:0010976]; regulation of transcription by RNA polymerase II [GO:0006357]; response to endoplasmic reticulum stress [GO:0034976]; response to unfolded protein [GO:0006986]; response to wounding [GO:0009611] chromatin [GO:0000785]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum [GO:0097038] "cAMP response element binding [GO:0035497]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; transcription cis-regulatory region binding [GO:0000976]" 0.89936 -0.61275 EVLESGEQGVLQWDRK 0 11.6314 0 0 0 0 0 0 0 0 9.42867 0 10.1852 0 0 0 0 0 0 0 0 0 0 0 0 10.265 0 Q70Z35 PREX2_HUMAN "Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (P-Rex2) (PtdIns(3,4,5)-dependent Rac exchanger 2) (DEP domain-containing protein 2)" PREX2 DEPDC2 Homo sapiens (Human) adult locomotory behavior [GO:0008344]; dendrite morphogenesis [GO:0048813]; G protein-coupled receptor signaling pathway [GO:0007186]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of GTPase activity [GO:0043547]; regulation of signaling [GO:0023051]; regulation of small GTPase mediated signal transduction [GO:0051056] cytosol [GO:0005829]; plasma membrane [GO:0005886] GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085] 0.92219 -1.1213 GVRLYCR 0 0 0 0 0 0 0 0 0 0 0 0 9.52205 0 0 11.019 0 0 0 0 0 0 0 0 0 0 0 Q70Z44 5HT3D_HUMAN 5-hydroxytryptamine receptor 3D (5-HT3-D) (5-HT3D) (Serotonin receptor 3D) HTR3D Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; inorganic cation transmembrane transport [GO:0098662]; monoatomic ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; serotonin receptor signaling pathway [GO:0007210]; signal transduction [GO:0007165] plasma membrane [GO:0005886]; serotonin-activated cation-selective channel complex [GO:1904602]; synapse [GO:0045202] neurotransmitter receptor activity [GO:0030594]; serotonin-gated monoatomic cation-selective channel activity [GO:0022850] 0.93977 -1.3242 MSRSFQIHHRTSFR 0 0 0 0 0 0 0 0 0 0 0 0 0 8.75556 0 0 0 0 0 0 0 0 0 0 0 0 0 Q70Z53 F10C1_HUMAN Protein FRA10AC1 FRA10AC1 C10orf4 PRO2972 Homo sapiens (Human) "dephosphorylation [GO:0016311]; mRNA splicing, via spliceosome [GO:0000398]" nucleus [GO:0005634] phosphatase activity [GO:0016791] 0.96978 -4.6993 ENKFGFRWR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9811 10.4062 0 0 Q719I0 AHSA2_HUMAN Putative activator of 90 kDa heat shock protein ATPase homolog 2 (Activator of HSP90 ATPase homolog 2 pseudogene) AHSA2P AHSA2 Homo sapiens (Human) positive regulation of ATP-dependent activity [GO:0032781]; protein folding [GO:0006457] cytosol [GO:0005829] ATPase activator activity [GO:0001671]; protein-folding chaperone binding [GO:0051087] 0.91399 -0.7789 MAKWGQGNPHWIVEER 0 0 0 0 10.2783 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q71DI3 H32_HUMAN Histone H3.2 (H3-clustered histone 13) (H3-clustered histone 14) (H3-clustered histone 15) (Histone H3/m) (Histone H3/o) H3C15 HIST2H3A; H3C14 H3F2 H3FM HIST2H3C; H3C13 HIST2H3D Homo sapiens (Human) nucleosome assembly [GO:0006334] extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634] DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; structural constituent of chromatin [GO:0030527] 0 3.0493 EIAQDFK 10.0668 10.0455 10.2293 0 0 0 0 9.3748 9.67756 0 10.455 11.328 0 0 0 0 0 0 10.5871 0 9.08874 0 0 0 0 0 0 Q71H61 ILDR2_HUMAN Immunoglobulin-like domain-containing receptor 2 (Angulin-3) ILDR2 C1orf32 Homo sapiens (Human) cell differentiation [GO:0030154]; homeostasis of number of cells within a tissue [GO:0048873]; insulin secretion [GO:0030073]; negative regulation of T cell activation [GO:0050868]; pancreas development [GO:0031016]; regulation of RNA splicing [GO:0043484]; response to glucose [GO:0009749] bicellular tight junction [GO:0005923]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; nucleus [GO:0005634]; tight junction [GO:0070160] 0.95895 -1.7731 ELAQFDPARR 0 9.01212 9.22944 0 10.331 0 8.78718 9.14873 8.94287 0 8.74049 9.5215 0 0 0 0 0 0 0 9.50263 0 0 0 0 0 0 9.49743 Q71RC2 LARP4_HUMAN La-related protein 4 (La ribonucleoprotein domain family member 4) LARP4 PP13296 Homo sapiens (Human) cytoskeleton organization [GO:0007010]; positive regulation of translation [GO:0045727]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of cell morphogenesis [GO:0022604]; translation [GO:0006412] cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; membrane [GO:0016020] mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723] 0.96938 -3.1891 DLIEDSSVQK 9.68463 0 0 0 0 0 0 0 0 9.34988 0 0 0 10.1513 0 0 0 0 0 9.19815 0 10.8234 0 0 10.2527 0 0 Q71SY5 MED25_HUMAN Mediator of RNA polymerase II transcription subunit 25 (Activator interaction domain-containing protein 1) (Activator-recruited cofactor 92 kDa component) (ARC92) (Mediator complex subunit 25) (p78) MED25 ACID1 ARC92 PTOV2 TCBAP0758 Homo sapiens (Human) negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of chromatin binding [GO:0035563]; positive regulation of mediator complex assembly [GO:2001178]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; RNA polymerase II preinitiation complex assembly [GO:0051123] core mediator complex [GO:0070847]; mediator complex [GO:0016592]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] nuclear retinoic acid receptor binding [GO:0042974]; nuclear retinoid X receptor binding [GO:0046965]; transcription coactivator binding [GO:0001223] 0.95369 -1.5225 DLESLKGLYR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2438 0 0 0 0 0 0 0 0 0 0 0 0 0 Q71U36 TBA1A_HUMAN Tubulin alpha-1A chain (EC 3.6.5.-) (Alpha-tubulin 3) (Tubulin B-alpha-1) (Tubulin alpha-3 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain] TUBA1A TUBA3 Homo sapiens (Human) adult locomotory behavior [GO:0008344]; cell division [GO:0051301]; cellular response to calcium ion [GO:0071277]; centrosome cycle [GO:0007098]; cerebellar cortex morphogenesis [GO:0021696]; cerebral cortex development [GO:0021987]; cytoskeleton-dependent intracellular transport [GO:0030705]; dentate gyrus development [GO:0021542]; forebrain morphogenesis [GO:0048853]; gene expression [GO:0010467]; glial cell differentiation [GO:0010001]; homeostasis of number of cells within a tissue [GO:0048873]; intracellular protein transport [GO:0006886]; memory [GO:0007613]; microtubule cytoskeleton organization [GO:0000226]; microtubule polymerization [GO:0046785]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; motor behavior [GO:0061744]; neuron apoptotic process [GO:0051402]; neuron migration [GO:0001764]; neuron projection arborization [GO:0140058]; organelle transport along microtubule [GO:0072384]; regulation of synapse organization [GO:0050807]; response to L-glutamate [GO:1902065]; response to mechanical stimulus [GO:0009612]; response to tumor necrosis factor [GO:0034612]; smoothened signaling pathway [GO:0007224]; startle response [GO:0001964]; synapse organization [GO:0050808]; visual learning [GO:0008542] condensed chromosome [GO:0000793]; cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; neuromuscular junction [GO:0031594]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037] GTP binding [GO:0005525]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; structural constituent of cytoskeleton [GO:0005200]; structural molecule activity [GO:0005198] 0 190.56 AVFVDLEPTVIDEVR 13.5427 13.2406 13.2708 12.5739 11.3547 12.1778 14.1801 14.4824 14.2922 12.6619 12.5357 13.075 13.7514 13.7422 14.1356 13.9182 14.1698 13.3585 14.1139 14.24 14.1243 13.7858 13.787 13.928 15.0275 14.9822 14.4859 Q71UI9 H2AV_HUMAN Histone H2A.V (H2A.F/Z) (H2A.Z variant histone 2) H2AZ2 H2AFV H2AV Homo sapiens (Human) extracellular exosome [GO:0070062]; nucleosome [GO:0000786]; nucleus [GO:0005634] DNA binding [GO:0003677]; molecular adaptor activity [GO:0060090]; protein heterodimerization activity [GO:0046982]; structural constituent of chromatin [GO:0030527] 0.92011 -1.1426 AGGKAGK 0 0 0 0 0 0 0 0 9.17283 0 0 9.01594 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q75N03 HAKAI_HUMAN E3 ubiquitin-protein ligase Hakai (EC 2.3.2.27) (Casitas B-lineage lymphoma-transforming sequence-like protein 1) (c-Cbl-like protein 1) (RING finger protein 188) (RING-type E3 ubiquitin transferase Hakai) CBLL1 HAKAI RNF188 Homo sapiens (Human) cell-cell adhesion [GO:0098609]; mRNA methylation [GO:0080009]; negative regulation of cell adhesion [GO:0007162]; positive regulation of cell migration [GO:0030335]; positive regulation of endocytosis [GO:0045807]; protein ubiquitination [GO:0016567]; regulation of cell adhesion [GO:0030155] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; RNA N6-methyladenosine methyltransferase complex [GO:0036396]; ubiquitin ligase complex [GO:0000151] identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.96517 -2.378 DDTPVHFCDKCGLPIK 0 0 0 0 0 0 0 0 10.6488 0 0 0 0 0 8.56255 0 9.73322 0 0 0 0 0 0 0 0 0 0 Q75N90 FBN3_HUMAN Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] FBN3 KIAA1776 Homo sapiens (Human) extracellular region [GO:0005576]; microfibril [GO:0001527] calcium ion binding [GO:0005509]; extracellular matrix structural constituent [GO:0005201] 0.92038 -0.91601 CSCGQGYSLMPDGR 0 0 0 0 0 0 10.2922 0 0 11.8669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q75T13 PGAP1_HUMAN GPI inositol-deacylase (EC 3.1.-.-) (Post-GPI attachment to proteins factor 1) (hPGAP1) PGAP1 UNQ3024/PRO9822 Homo sapiens (Human) anterior/posterior axis specification [GO:0009948]; attachment of GPI anchor to protein [GO:0016255]; embryonic pattern specification [GO:0009880]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; forebrain regionalization [GO:0021871]; GPI anchor metabolic process [GO:0006505]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; protein transport [GO:0015031]; sensory perception of sound [GO:0007605] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789] "hydrolase activity, acting on ester bonds [GO:0016788]; phosphatidylinositol deacylase activity [GO:0050185]" 0.92412 -1.0148 QLQLTTVR 0 0 0 0 0 0 11.4637 0 0 10.687 0 0 9.92813 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q75WM6 H1FNT_HUMAN Testis-specific H1 histone (Haploid germ cell-specific nuclear protein 1) (Histone H1.7) (Histone H1t2) H1-7 H1FNT HANP1 Homo sapiens (Human) chromosome condensation [GO:0030261]; negative regulation of DNA recombination [GO:0045910]; sperm DNA condensation [GO:0035092]; spermatid nucleus elongation [GO:0007290] chromatin [GO:0000785]; nucleus [GO:0005634] ATP binding [GO:0005524]; double-stranded DNA binding [GO:0003690]; nucleosomal DNA binding [GO:0031492] 0.96882 -3.3185 EPPCARAKEEAGATAADEGR 0 9.80187 0 0 0 0 9.72824 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q76B58 BRNP3_HUMAN BMP/retinoic acid-inducible neural-specific protein 3 (DBCCR1-like protein 1) BRINP3 DBCCR1L DBCCR1L1 FAM5C Homo sapiens (Human) cell cycle [GO:0007049]; cellular response to retinoic acid [GO:0071300]; central nervous system neuron differentiation [GO:0021953]; negative regulation of cell cycle [GO:0045786]; negative regulation of mitotic cell cycle [GO:0045930]; nervous system development [GO:0007399]; positive regulation of neuron differentiation [GO:0045666] cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025] 0.96413 -2.2685 LNSWFDPSWR 0 0 0 0 10.0283 0 0 0 0 0 0 0 0 11.386 0 0 0 0 0 0 0 0 0 0 0 0 0 Q76FK4 NOL8_HUMAN Nucleolar protein 8 (Nucleolar protein Nop132) NOL8 C9orf34 NOP132 Homo sapiens (Human) protein localization to nucleolus [GO:1902570]; rRNA processing [GO:0006364] chromosome [GO:0005694]; nucleolus [GO:0005730] RNA binding [GO:0003723] 0.9697 -4.7044 DIIHYDPTK 0 0 0 12.0612 0 0 0 0 0 11.337 0 0 11.5507 0 11.7446 0 0 0 0 0 0 0 0 0 9.97025 0 0 Q76KP1 B4GN4_HUMAN "N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4)" B4GALNT4 Homo sapiens (Human) Golgi cisterna membrane [GO:0032580] acetylgalactosaminyltransferase activity [GO:0008376]; N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity [GO:0033842] 0.16391 0.9882 AARPLPLFLGR 9.32233 0 0 0 0 0 0 0 0 0 0 0 0 0 9.12689 0 0 0 0 0 0 0 0 0 0 0 0 Q76L83 ASXL2_HUMAN Putative Polycomb group protein ASXL2 (Additional sex combs-like protein 2) ASXL2 ASXH2 KIAA1685 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360]; positive regulation of transcription by RNA polymerase II [GO:0045944] nucleoplasm [GO:0005654]; PR-DUB complex [GO:0035517] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; peroxisome proliferator activated receptor binding [GO:0042975] 0.96727 -3.7037 LDNEKLNPTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.69723 0 0 8.66775 0 0 Q76M96 CCD80_HUMAN Coiled-coil domain-containing protein 80 (Down-regulated by oncogenes protein 1) (Up-regulated in BRS-3 deficient mouse homolog) CCDC80 DRO1 URB HBE245 Homo sapiens (Human) extracellular matrix organization [GO:0030198]; positive regulation of cell-substrate adhesion [GO:0010811]; response to bacterium [GO:0009617] basement membrane [GO:0005604]; extracellular region [GO:0005576]; interstitial matrix [GO:0005614] fibronectin binding [GO:0001968]; heparin binding [GO:0008201] 0.96786 -2.9933 EMIRDEGSSAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.62443 0 0 0 8.86731 0 0 9.1134 0 0 0 Q76N89 HECW1_HUMAN "E3 ubiquitin-protein ligase HECW1 (EC 2.3.2.26) (HECT, C2 and WW domain-containing protein 1) (HECT-type E3 ubiquitin transferase HECW1) (NEDD4-like E3 ubiquitin-protein ligase 1) (hNEDL1)" HECW1 KIAA0322 NEDL1 Homo sapiens (Human) negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; protein ubiquitination [GO:0016567]; regulation of dendrite morphogenesis [GO:0048814] cytoplasm [GO:0005737]; cytosol [GO:0005829] ubiquitin protein ligase activity [GO:0061630] 0.50771 0.60617 EYIERMVK 0 8.82228 0 0 0 0 0 13.9206 0 8.71884 10.3567 10.5113 0 0 0 0 13.5398 0 10.3463 0 9.16284 0 0 0 0 11.4629 0 Q76NI1 KNDC1_HUMAN Kinase non-catalytic C-lobe domain-containing protein 1 (KIND domain-containing protein 1) (Cerebral protein 9) (Protein very KIND) (v-KIND) (Ras-GEF domain-containing family member 2) KNDC1 C10orf23 KIAA1768 RASGEF2 VKIND hucep-9 Homo sapiens (Human) cerebellar granule cell differentiation [GO:0021707]; positive regulation of protein phosphorylation [GO:0001934]; regulation of dendrite development [GO:0050773]; regulation of dendrite morphogenesis [GO:0048814]; small GTPase mediated signal transduction [GO:0007264] dendrite [GO:0030425]; guanyl-nucleotide exchange factor complex [GO:0032045]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204] guanyl-nucleotide exchange factor activity [GO:0005085] 0.88357 -0.31988 ALLSTPVR 0 0 14.3987 12.0078 11.6133 11.8151 14.4425 14.4437 14.3855 14.2223 0 14.4132 11.6107 11.857 11.9728 12.4347 12.2246 12.9248 9.37171 11.3785 10.3124 11.3127 10.3982 11.3166 12.402 13.0267 0 Q7KYR7 BT2A1_HUMAN Butyrophilin subfamily 2 member A1 BTN2A1 BT2.1 BTF1 Homo sapiens (Human) lipid metabolic process [GO:0006629]; regulation of cytokine production [GO:0001817]; T cell receptor signaling pathway [GO:0050852] external side of plasma membrane [GO:0009897]; plasma membrane [GO:0005886] signaling receptor binding [GO:0005102] 0.95202 -1.3962 EKLQEELRWR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.6805 9.14183 8.4731 Q7KZ85 SPT6H_HUMAN Transcription elongation factor SPT6 (hSPT6) (Histone chaperone suppressor of Ty6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein) SUPT6H KIAA0162 SPT6H Homo sapiens (Human) blastocyst formation [GO:0001825]; mRNA processing [GO:0006397]; mRNA transcription by RNA polymerase II [GO:0042789]; mRNA transport [GO:0051028]; nucleosome organization [GO:0034728]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; regulation of isotype switching [GO:0045191]; regulation of mRNA export from nucleus [GO:0010793]; regulation of mRNA processing [GO:0050684]; regulation of muscle cell differentiation [GO:0051147]; RNA splicing [GO:0008380]; transcription elongation by RNA polymerase II [GO:0006368]; transcription elongation-coupled chromatin remodeling [GO:0140673] nucleoplasm [GO:0005654]; transcription elongation factor complex [GO:0008023] DNA binding [GO:0003677]; histone binding [GO:0042393]; nucleosome binding [GO:0031491]; RNA binding [GO:0003723] 0.96903 -7.1239 DAQMLIEDVK 0 0 0 0 0 0 0 0 10.0942 9.22415 0 0 0 12.0508 0 0 0 0 0 0 0 0 9.32166 0 0 0 11.35 Q7KZF4 SND1_HUMAN Staphylococcal nuclease domain-containing protein 1 (EC 3.1.31.1) (100 kDa coactivator) (EBNA2 coactivator p100) (Tudor domain-containing protein 11) (p100 co-activator) SND1 TDRD11 Homo sapiens (Human) miRNA catabolic process [GO:0010587]; mRNA catabolic process [GO:0006402]; osteoblast differentiation [GO:0001649]; regulation of cell cycle process [GO:0010564]; RNA-mediated gene silencing [GO:0031047] cytosol [GO:0005829]; dense body [GO:0097433]; extracellular exosome [GO:0070062]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleus [GO:0005634]; RISC complex [GO:0016442] "cadherin binding [GO:0045296]; endonuclease activity [GO:0004519]; endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters [GO:0016894]; nuclease activity [GO:0004518]; RISC complex binding [GO:1905172]; RNA binding [GO:0003723]; RNA endonuclease activity [GO:0004521]; transcription coregulator activity [GO:0003712]" 0 6.6861 LEGENTQDK 0 0 0 0 0 0 0 10.5389 8.98741 9.73569 9.24719 0 0 0 0 0 10.1501 0 0 0 0 0 0 0 10.7449 11.5773 11.3934 Q7KZI7 MARK2_HUMAN Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2) (PAR1 homolog) (PAR1 homolog b) (Par-1b) (Par1b) MARK2 EMK1 Homo sapiens (Human) activation of protein kinase activity [GO:0032147]; autophagy of mitochondrion [GO:0000422]; axon development [GO:0061564]; establishment of cell polarity [GO:0030010]; establishment or maintenance of cell polarity regulating cell shape [GO:0071963]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular signal transduction [GO:0035556]; microtubule cytoskeleton organization [GO:0000226]; mitochondrion localization [GO:0051646]; neuron migration [GO:0001764]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of neuron projection development [GO:0010976]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule binding [GO:1904526]; regulation of microtubule cytoskeleton organization [GO:0070507]; Wnt signaling pathway [GO:0016055] actin filament [GO:0005884]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; lateral plasma membrane [GO:0016328]; membrane [GO:0016020]; microtubule bundle [GO:0097427]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; cadherin binding [GO:0045296]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; protein kinase activator activity [GO:0030295]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321] 0.96927 -5.7182 FIVHRDLK 0 0 0 10.0897 0 9.77403 0 0 0 0 0 0 0 9.86462 0 0 0 0 0 0 0 0 0 0 0 0 9.81984 Q7KZN9 COX15_HUMAN Cytochrome c oxidase assembly protein COX15 homolog COX15 Homo sapiens (Human) "cellular respiration [GO:0045333]; heme A biosynthetic process [GO:0006784]; heme biosynthetic process [GO:0006783]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; proton transmembrane transport [GO:1902600]; respiratory chain complex IV assembly [GO:0008535]; respiratory gaseous exchange by respiratory system [GO:0007585]" cytochrome complex [GO:0070069]; mitochondrial inner membrane [GO:0005743]; mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] "cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; molecular adaptor activity [GO:0060090]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]" 0.79105 0.24614 LPETHQLLQLR 0 0 0 0 0 0 8.53317 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7L014 DDX46_HUMAN Probable ATP-dependent RNA helicase DDX46 (EC 3.6.4.13) (DEAD box protein 46) (PRP5 homolog) DDX46 KIAA0801 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; U2-type prespliceosome assembly [GO:1903241]" Cajal body [GO:0015030]; fibrillar center [GO:0001650]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2 snRNP [GO:0005686] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.96961 -3.95 AGRTGRAGNK 0 0 0 0 8.29655 9.64169 0 0 0 9.55273 14.14 0 9.81511 0 0 0 7.76082 0 0 9.77375 9.85354 11.3226 0 10.7075 0 12.9494 0 Q7L099 RUFY3_HUMAN Protein RUFY3 (RUN and FYVE domain-containing protein 3) (Rap2-interacting protein x) (RIPx) (Single axon-regulated protein) (Singar) RUFY3 KIAA0871 Homo sapiens (Human) actin filament organization [GO:0007015]; cell differentiation [GO:0030154]; negative regulation of axonogenesis [GO:0050771]; nervous system development [GO:0007399]; positive regulation of axon extension [GO:0045773]; positive regulation of cell migration [GO:0030335]; positive regulation of intracellular protein transport [GO:0090316]; regulation of axonogenesis [GO:0050770]; regulation of establishment of cell polarity [GO:2000114] anchoring junction [GO:0070161]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endomembrane system [GO:0012505]; filopodium [GO:0030175]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204] 0.9574 -1.6513 MNLMNMAKLSIK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.53976 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7L0X2 ERIP6_HUMAN Glutamate-rich protein 6 (Protein FAM194A) ERICH6 C3orf44 FAM194A Homo sapiens (Human) 0.92313 -1.0808 EKAEPECLASK 0 0 0 0 0 9.43033 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7L0Y3 TM10C_HUMAN tRNA methyltransferase 10 homolog C (HBV pre-S2 trans-regulated protein 2) (Mitochondrial ribonuclease P protein 1) (Mitochondrial RNase P protein 1) (RNA (guanine-9-)-methyltransferase domain-containing protein 1) (Renal carcinoma antigen NY-REN-49) (mRNA methyladenosine-N(1)-methyltransferase) (EC 2.1.1.-) (tRNA (adenine(9)-N(1))-methyltransferase) (EC 2.1.1.218) (tRNA (guanine(9)-N(1))-methyltransferase) (EC 2.1.1.221) TRMT10C MRPP1 RG9MTD1 Homo sapiens (Human) mitochondrial RNA 5'-end processing [GO:0000964]; mitochondrial tRNA 3'-end processing [GO:1990180]; mitochondrial tRNA 5'-end processing [GO:0097745]; mitochondrial tRNA methylation [GO:0070901]; mitochondrial tRNA processing [GO:0090646]; mRNA methylation [GO:0080009]; positive regulation of mitochondrial translation [GO:0070131] mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrial ribonuclease P complex [GO:0030678]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tRNA methyltransferase complex [GO:0043527] identical protein binding [GO:0042802]; mRNA (adenine-N1-)-methyltransferase activity [GO:0061953]; RNA binding [GO:0003723]; tRNA (adenine-N1-)-methyltransferase activity [GO:0016429]; tRNA (guanine(9)-N(1))-methyltransferase activity [GO:0052905]; tRNA (guanine-N1-)-methyltransferase activity [GO:0009019]; tRNA binding [GO:0000049] 0.91514 -0.79084 FLVPFTLHRKR 0 0 9.36761 0 0 0 0 0 0 0 9.15947 0 0 0 0 9.42501 0 0 0 0 0 0 0 0 0 0 0 Q7L1Q6 5MP2_HUMAN eIF5-mimic protein 2 (Basic leucine zipper and W2 domain-containing protein 1) (Protein Orf) BZW1 5MP2 BZAP45 KIAA0005 Homo sapiens (Human) regulation of translational initiation [GO:0006446] cytoplasm [GO:0005737]; membrane [GO:0016020] cadherin binding [GO:0045296]; RNA binding [GO:0003723] 0.79456 0.24456 DINAVAASLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.83709 0 0 0 0 0 0 Q7L1S5 CHST9_HUMAN Carbohydrate sulfotransferase 9 (EC 2.8.2.-) (GalNAc-4-O-sulfotransferase 2) (GalNAc-4-ST2) (GalNAc4ST-2) (N-acetylgalactosamine-4-O-sulfotransferase 2) CHST9 UNQ2549/PRO6175 Homo sapiens (Human) carbohydrate biosynthetic process [GO:0016051]; chondroitin sulfate biosynthetic process [GO:0030206]; glycosaminoglycan metabolic process [GO:0030203]; hormone biosynthetic process [GO:0042446]; proteoglycan biosynthetic process [GO:0030166]; sulfur compound metabolic process [GO:0006790] extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; membrane [GO:0016020] chondroitin 4-sulfotransferase activity [GO:0047756]; N-acetylgalactosamine 4-O-sulfotransferase activity [GO:0001537]; sulfotransferase activity [GO:0008146] 0.84439 0.1357 FHMPEDVREK 0 0 0 0 0 0 0 0 0 0 0 8.49422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7L1T6 NB5R4_HUMAN Cytochrome b5 reductase 4 (EC 1.6.2.2) (Flavohemoprotein b5/b5R) (b5+b5R) (N-terminal cytochrome b5 and cytochrome b5 oxidoreductase domain-containing protein) (cb5/cb5R) CYB5R4 NCB5OR Homo sapiens (Human) bicarbonate transport [GO:0015701]; cell development [GO:0048468]; detection of oxygen [GO:0003032]; generation of precursor metabolites and energy [GO:0006091]; glucose homeostasis [GO:0042593]; insulin secretion [GO:0030073]; reactive oxygen species metabolic process [GO:0072593]; response to antibiotic [GO:0046677]; superoxide metabolic process [GO:0006801] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; perinuclear region of cytoplasm [GO:0048471] "cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NAD(P)H oxidase H2O2-forming activity [GO:0016174]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]" 0.96205 -2.6211 DINLDSIIVDHQNDSFR 0 0 0 0 0 9.2124 0 0 0 0 0 0 0 0 0 11.2262 0 0 0 0 0 0 0 0 0 0 0 Q7L1V2 MON1B_HUMAN Vacuolar fusion protein MON1 homolog B (HSV-1 stimulation-related gene 1 protein) (HSV-I stimulating-related protein) MON1B HSRG1 KIAA0872 SAND2 Homo sapiens (Human) early viral transcription [GO:0019085]; late viral transcription [GO:0019086]; protein targeting to vacuole [GO:0006623]; vesicle-mediated transport [GO:0016192] cytoplasm [GO:0005737]; Mon1-Ccz1 complex [GO:0035658] 0.96092 -2.0106 LFIRYPPK 9.91577 0 0 0 0 0 0 8.73762 0 0 0 8.61504 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7L211 ABHDD_HUMAN Protein ABHD13 (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 13) (Abhydrolase domain-containing protein 13) ABHD13 C13orf6 Homo sapiens (Human) protein depalmitoylation [GO:0002084] dendrite cytoplasm [GO:0032839]; membrane [GO:0016020] palmitoyl-(protein) hydrolase activity [GO:0008474] 0.89834 -0.59258 YLPLWCYKNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3165 0 0 0 0 0 0 Q7L273 KCTD9_HUMAN BTB/POZ domain-containing protein KCTD9 KCTD9 Homo sapiens (Human) intracellular signal transduction [GO:0035556]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567] cullin family protein binding [GO:0097602]; identical protein binding [GO:0042802]; protein self-association [GO:0043621] 0.86387 0.076271 QDHRGAFLIDR 0 0 0 0 0 0 0 0 0 0 0 9.67214 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7L2E3 DHX30_HUMAN ATP-dependent RNA helicase DHX30 (EC 3.6.4.13) (DEAH box protein 30) DHX30 DDX30 KIAA0890 Homo sapiens (Human) central nervous system development [GO:0007417]; mitochondrial large ribosomal subunit assembly [GO:1902775] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; ribonucleoprotein granule [GO:0035770] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; chromatin binding [GO:0003682]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; G-quadruplex RNA binding [GO:0002151]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.88371 -0.12396 ALGISHAK 0 0 0 0 0 0 0 0 9.44332 0 0 0 0 0 0 0 0 0 0 0 0 0 7.59619 0 10.0151 10.0171 0 Q7L2H7 EIF3M_HUMAN Eukaryotic translation initiation factor 3 subunit M (eIF3m) (Fetal lung protein B5) (hFL-B5) (PCI domain-containing protein 1) EIF3M HFLB5 PCID1 GA17 PNAS-125 Homo sapiens (Human) cytoplasmic translational initiation [GO:0002183]; formation of cytoplasmic translation initiation complex [GO:0001732]; translational initiation [GO:0006413] "cytosol [GO:0005829]; eukaryotic 43S preinitiation complex [GO:0016282]; eukaryotic 48S preinitiation complex [GO:0033290]; eukaryotic translation initiation factor 3 complex [GO:0005852]; eukaryotic translation initiation factor 3 complex, eIF3m [GO:0071541]" translation initiation factor activity [GO:0003743]; translation initiation factor binding [GO:0031369] 0.71311 0.36699 EGERPSLR 0 10.7016 0 0 0 9.06676 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.91664 0 0 Q7L2J0 MEPCE_HUMAN 7SK snRNA methylphosphate capping enzyme (MePCE) (EC 2.1.1.-) (Bicoid-interacting protein 3 homolog) (Bin3 homolog) MEPCE BCDIN3 Homo sapiens (Human) negative regulation of chromatin binding [GO:0035562]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of protein localization to Cajal body [GO:1904871]; positive regulation of snRNA transcription by RNA polymerase II [GO:1905382]; RNA methylation [GO:0001510]; snRNA metabolic process [GO:0016073]; snRNA modification [GO:0040031] 7SK snRNP [GO:0120259]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] 7SK snRNA binding [GO:0097322]; O-methyltransferase activity [GO:0008171]; RNA 5'-methyltransferase activity [GO:1990276]; RNA binding [GO:0003723]; RNA methyltransferase activity [GO:0008173]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; snRNA binding [GO:0017069] 0.36735 0.74036 GGGQGSK 0 0 0 0 0 0 0 0 0 0 8.98279 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7L311 ARMX2_HUMAN Armadillo repeat-containing X-linked protein 2 (ARM protein lost in epithelial cancers on chromosome X 2) (Protein ALEX2) ARMCX2 ALEX2 KIAA0512 Homo sapiens (Human) mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739] 0.96771 -2.3351 GVTRSRNGGK 0 0 0 0 0 0 0 9.19177 9.13296 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.36269 Q7L3B6 CD37L_HUMAN Hsp90 co-chaperone Cdc37-like 1 (Hsp90-associating relative of Cdc37) CDC37L1 CDC37B HARC Homo sapiens (Human) protein folding [GO:0006457]; protein stabilization [GO:0050821] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; platelet dense granule lumen [GO:0031089] heat shock protein binding [GO:0031072]; protein-folding chaperone binding [GO:0051087]; unfolded protein binding [GO:0051082] 0.91848 -0.88053 LFFQKAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.41502 Q7L3S4 ZN771_HUMAN Zinc finger protein 771 (Mesenchymal stem cell protein DSC43) ZNF771 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.88593 -0.29455 LYICAGCGRDFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.67066 0 10.0318 9.586 0 0 0 0 0 0 0 0 0 Q7L3T8 SYPM_HUMAN "Probable proline--tRNA ligase, mitochondrial (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS)" PARS2 Homo sapiens (Human) prolyl-tRNA aminoacylation [GO:0006433] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; identical protein binding [GO:0042802]; proline-tRNA ligase activity [GO:0004827] 0.88452 -0.14657 CRALPALATCSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0773 0 0 0 0 Q7L4E1 MIGA2_HUMAN Mitoguardin 2 (Protein FAM73B) MIGA2 C9orf54 FAM73B PSEC0112 Homo sapiens (Human) bone development [GO:0060348]; mitochondrial fusion [GO:0008053] mitochondrial outer membrane [GO:0005741]; plasma membrane [GO:0005886] protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803] 0.88367 -0.27902 VGRQMVTGLMTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2336 0 0 Q7L4I2 RSRC2_HUMAN Arginine/serine-rich coiled-coil protein 2 RSRC2 Homo sapiens (Human) RNA binding [GO:0003723] 0.96963 -3.1252 DGLAPEKTSPDR 13.333 12.999 0 0 0 0 12.5454 0 0 9.92689 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7L4P6 BEND5_HUMAN BEN domain-containing protein 5 BEND5 C1orf165 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892] Golgi apparatus [GO:0005794] DNA binding [GO:0003677] 0.89865 -0.59229 DFSPRSRLDFDNQK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.68583 0 0 0 0 0 0 0 0 0 0 10.4786 11.3006 9.9112 Q7L4S7 ARMX6_HUMAN Protein ARMCX6 ARMCX6 Homo sapiens (Human) mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739] 0.84854 0.17174 MYINEVCR 0 0 0 0 0 0 0 0 9.00927 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7L513 FCRLA_HUMAN Fc receptor-like A (Fc receptor homolog expressed in B-cells) (Fc receptor-like and mucin-like protein 1) (Fc receptor-like protein) (Fc receptor-related protein X) (FcRX) FCRLA FCRL FCRL1 FCRLM1 FCRX FREB UNQ291/PRO329 Homo sapiens (Human) cell differentiation [GO:0030154]; cell surface receptor signaling pathway [GO:0007166] cytoplasm [GO:0005737] transmembrane signaling receptor activity [GO:0004888] 0.7614 0.29072 LLFSFYK 9.01898 0 0 0 0 0 0 0 0 0 0 0 0 10.1727 0 0 0 0 0 0 0 0 10.149 9.93858 0 0 0 Q7L576 CYFP1_HUMAN Cytoplasmic FMR1-interacting protein 1 (Specifically Rac1-associated protein 1) (Sra-1) (p140sra-1) CYFIP1 KIAA0068 Homo sapiens (Human) "axon extension [GO:0048675]; axon guidance [GO:0007411]; cell morphogenesis [GO:0000902]; cellular response to insulin stimulus [GO:0032869]; cognition [GO:0050890]; dendrite extension [GO:0097484]; lamellipodium assembly [GO:0030032]; modification of synaptic structure [GO:0099563]; negative regulation of synaptic vesicle recycling [GO:1903422]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; positive regulation of axon extension [GO:0045773]; positive regulation of dendrite development [GO:1900006]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neurotrophin TRK receptor signaling pathway [GO:0051388]; positive regulation of ruffle assembly [GO:1900029]; Rac protein signal transduction [GO:0016601]; regulation of actin filament polymerization [GO:0030833]; regulation of cell shape [GO:0008360]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of myelination [GO:0031641]; regulation of translation [GO:0006417]; regulation of translation at postsynapse, modulating synaptic transmission [GO:0099578]; response to electrical stimulus [GO:0051602]; ruffle organization [GO:0031529]" axonal growth cone [GO:0044295]; central region of growth cone [GO:0090724]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; filopodium tip [GO:0032433]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; mRNA cap binding complex [GO:0005845]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471]; peripheral region of growth cone [GO:0090725]; ruffle [GO:0001726]; SCAR complex [GO:0031209]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]; synapse [GO:0045202]; terminal bouton [GO:0043195]; tertiary granule lumen [GO:1904724] actin filament binding [GO:0051015]; RNA 7-methylguanosine cap binding [GO:0000340]; small GTPase binding [GO:0031267]; translation regulator activity [GO:0045182] 0.58674 0.46787 DIVEYAELK 0 0 0 0 0 0 9.49392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1844 0 0 0 0 Q7L590 MCM10_HUMAN Protein MCM10 homolog (HsMCM10) MCM10 PRO2249 Homo sapiens (Human) cell population proliferation [GO:0008283]; DNA damage response [GO:0006974]; DNA replication initiation [GO:0006270] nuclear replication fork [GO:0043596]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA replication origin binding [GO:0003688]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697] 0.96324 -2.4412 ASPPDPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.80426 0 0 0 0 0 0 0 Q7L591 DOK3_HUMAN Docking protein 3 (Downstream of tyrosine kinase 3) DOK3 Homo sapiens (Human) positive regulation of MAPK cascade [GO:0043410]; Ras protein signal transduction [GO:0007265]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] cytoplasm [GO:0005737]; ficolin-1-rich granule membrane [GO:0101003]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667] 0.93235 -1.2863 SAGPGRRGER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4662 0 0 0 Q7L592 NDUF7_HUMAN "Protein arginine methyltransferase NDUFAF7, mitochondrial (EC 2.1.1.320) (NADH dehydrogenase [ubiquinone] complex I, assembly factor 7) (Protein midA homolog)" NDUFAF7 C2orf56 PRO1853 Homo sapiens (Human) "mitochondrial respiratory chain complex I assembly [GO:0032981]; peptidyl-arginine methylation, to symmetrical-dimethyl arginine [GO:0019918]" extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] enzyme binding [GO:0019899]; methyltransferase activity [GO:0008168]; protein-arginine omega-N symmetric methyltransferase activity [GO:0035243] 0.8708 0.063885 EVFVDIDPQVSDK 0 9.83663 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7L5A8 FA2H_HUMAN Fatty acid 2-hydroxylase (EC 1.14.18.-) (Fatty acid alpha-hydroxylase) (Fatty acid hydroxylase domain-containing protein 1) FA2H FAAH FAXDC1 Homo sapiens (Human) central nervous system myelin maintenance [GO:0032286]; ceramide biosynthetic process [GO:0046513]; establishment of skin barrier [GO:0061436]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]; galactosylceramide biosynthetic process [GO:0006682]; glucosylceramide biosynthetic process [GO:0006679]; lipid modification [GO:0030258]; peripheral nervous system myelin maintenance [GO:0032287]; plasma membrane raft organization [GO:0044857]; regulation of acinar cell proliferation [GO:1904697]; regulation of hair cycle [GO:0042634]; regulation of sebum secreting cell proliferation [GO:1904002]; sebaceous gland cell differentiation [GO:0001949]; sphingolipid biosynthetic process [GO:0030148] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] fatty acid alpha-hydroxylase activity [GO:0080132]; heme binding [GO:0020037]; iron ion binding [GO:0005506] 0.90209 -0.7026 LAAGACWVRR 0 0 0 10.9699 0 11.0464 0 0 0 0 0 0 0 11.1625 0 11.8801 0 0 0 0 0 0 0 0 0 0 0 Q7L5Y9 MAEA_HUMAN E3 ubiquitin-protein transferase MAEA (EC 2.3.2.27) (Cell proliferation-inducing gene 5 protein) (Erythroblast macrophage protein) (Human lung cancer oncogene 10 protein) (HLC-10) (Macrophage erythroblast attacher) (P44EMLP) MAEA EMP HLC10 PIG5 Homo sapiens (Human) cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; cytoskeleton organization [GO:0007010]; enucleate erythrocyte development [GO:0048822]; erythrocyte maturation [GO:0043249]; negative regulation of myeloid cell apoptotic process [GO:0033033]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of mitotic cell cycle [GO:0007346] actomyosin contractile ring [GO:0005826]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; GID complex [GO:0034657]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; spindle [GO:0005819]; ubiquitin ligase complex [GO:0000151] actin binding [GO:0003779]; metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630] 0.92295 -1.0623 ETATCLAWCHDNK 0 0 0 0 0 0 9.16128 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.64366 0 0 0 0 0 Q7L622 G2E3_HUMAN G2/M phase-specific E3 ubiquitin-protein ligase (EC 2.3.2.26) (G2/M phase-specific HECT-type E3 ubiquitin transferase) G2E3 KIAA1333 Homo sapiens (Human) apoptotic process [GO:0006915]; protein ubiquitination [GO:0016567] cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; nucleolus [GO:0005730]; nucleus [GO:0005634] metal ion binding [GO:0046872]; ubiquitin-protein transferase activity [GO:0004842] 0.91336 -0.82166 ASKLKCCVCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.5244 0 0 0 0 9.97226 0 Q7L7X3 TAOK1_HUMAN Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) (hKFC-B) (MARK Kinase) (MARKK) (Prostate-derived sterile 20-like kinase 2) (PSK-2) (PSK2) (Prostate-derived STE20-like kinase 2) (Thousand and one amino acid protein kinase 1) (TAOK1) (hTAOK1) TAOK1 KIAA1361 MAP3K16 MARKK Homo sapiens (Human) central nervous system neuron development [GO:0021954]; DNA damage response [GO:0006974]; DNA repair [GO:0006281]; execution phase of apoptosis [GO:0097194]; microtubule cytoskeleton organization [GO:0000226]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of microtubule depolymerization [GO:0007026]; neuron cellular homeostasis [GO:0070050]; phosphorylation [GO:0016310]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein acetylation [GO:1901985]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule cytoskeleton organization [GO:0070507] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule cytoskeleton [GO:0015630]; perinuclear region of cytoplasm [GO:0048471] alpha-tubulin binding [GO:0043014]; ATP binding [GO:0005524]; beta-tubulin binding [GO:0048487]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activator activity [GO:0043539]; protein serine/threonine kinase activity [GO:0004674]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321]; transferase activity [GO:0016740] 0.96743 -2.7991 AGNILLTEPGQVK 0 0 11.703 0 0 0 11.7934 10.9418 9.59546 10.4638 0 0 0 0 0 10.5237 0 0 0 0 0 0 0 0 8.92276 0 9.31164 Q7L804 RFIP2_HUMAN Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11) RAB11FIP2 KIAA0941 Homo sapiens (Human) establishment of cell polarity [GO:0030010]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; phagocytosis [GO:0006909]; positive regulation of GTPase activity [GO:0043547]; regulated exocytosis [GO:0045055]; TRAM-dependent toll-like receptor 4 signaling pathway [GO:0035669] cell projection [GO:0042995]; cytoplasmic vesicle membrane [GO:0030659]; endosome [GO:0005768]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; phagocytic cup [GO:0001891]; recycling endosome membrane [GO:0055038] identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; small GTPase binding [GO:0031267] 0.89843 -0.58658 LESKQGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.7652 0 0 0 0 0 0 12.701 10.9212 0 Q7L8A9 VASH1_HUMAN Tubulinyl-Tyr carboxypeptidase 1 (EC 3.4.17.17) (Tubulin carboxypeptidase 1) (Tyrosine carboxypeptidase 1) (TTCP 1) (Vasohibin-1) VASH1 KIAA1036 VASH Homo sapiens (Human) angiogenesis [GO:0001525]; cell cycle [GO:0007049]; labyrinthine layer blood vessel development [GO:0060716]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of lymphangiogenesis [GO:1901491]; proteolysis [GO:0006508]; regulation of angiogenesis [GO:0045765]; regulation of cell cycle [GO:0051726]; regulation of cellular senescence [GO:2000772]; response to wounding [GO:0009611] apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615] actin binding [GO:0003779]; metallocarboxypeptidase activity [GO:0004181]; tubulin-tyrosine carboxypeptidase [GO:0106423] 0.92461 -1.0013 LGQSVSHDPHSVEQIEWK 0 0 9.13489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7L8J4 3BP5L_HUMAN SH3 domain-binding protein 5-like (SH3BP-5-like) SH3BP5L KIAA1720 UNQ2766/PRO7133 Homo sapiens (Human) intracellular signal transduction [GO:0035556]; negative regulation of protein tyrosine kinase activity [GO:0061099] cytoplasm [GO:0005737] guanyl-nucleotide exchange factor activity [GO:0005085]; protein kinase inhibitor activity [GO:0004860] 0.9617 -2.4663 ARPYYEARRLAK 0 0 0 0 0 0 0 11.9816 0 0 0 0 0 0 0 9.77862 0 0 0 0 0 0 0 0 0 0 9.04262 Q7L8L6 FAKD5_HUMAN "FAST kinase domain-containing protein 5, mitochondrial" FASTKD5 KIAA1792 Homo sapiens (Human) mitochondrial RNA processing [GO:0000963]; mRNA processing [GO:0006397]; regulation of mitochondrial mRNA stability [GO:0044528] mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; ribonucleoprotein granule [GO:0035770] RNA binding [GO:0003723]; rRNA binding [GO:0019843] 0.95497 -1.5191 EATPAENVAKLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.05805 0 0 0 0 0 0 0 0 0 0 0 0 Q7L8W6 DPH6_HUMAN Diphthine--ammonia ligase (EC 6.3.1.14) (ATP-binding domain-containing protein 4) (Diphthamide synthase) (Diphthamide synthetase) (Protein DPH6 homolog) DPH6 ATPBD4 Homo sapiens (Human) peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183] cytosol [GO:0005829] ATP binding [GO:0005524]; diphthine-ammonia ligase activity [GO:0017178] 0.87642 -0.0084778 VSSVPDNYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0611 0 0 0 0 Q7L945 ZN627_HUMAN Zinc finger protein 627 ZNF627 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.97007 -5.3405 HTGNGPYKCK 0 0 0 0 0 0 0 0 0 10.1795 0 0 0 0 0 0 9.54747 0 0 0 0 0 0 0 0 0 0 Q7L985 LIGO2_HUMAN Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 (Leucine-rich repeat neuronal protein 3) (Leucine-rich repeat neuronal protein 6C) LINGO2 LERN3 LRRN6C UNQ9234/PRO31993 Homo sapiens (Human) extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; membrane [GO:0016020] 0.82389 0.21519 NSIDLEYVPR 0 0 0 0 0 8.62724 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7L9B9 EEPD1_HUMAN Endonuclease/exonuclease/phosphatase family domain-containing protein 1 EEPD1 KIAA1706 Homo sapiens (Human) DNA repair [GO:0006281]; positive regulation of cholesterol efflux [GO:0010875] plasma membrane [GO:0005886] DNA binding [GO:0003677] 0.90323 -0.70439 DPSDLSHSR 15.3858 15.4896 15.4348 0 0 0 0 0 15.0809 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7LBC6 KDM3B_HUMAN Lysine-specific demethylase 3B (EC 1.14.11.65) (JmjC domain-containing histone demethylation protein 2B) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA) ([histone H3]-dimethyl-L-lysine(9) demethylase 3B) KDM3B C5orf7 JHDM2B JMJD1B KIAA1082 Homo sapiens (Human) histone H3-K9 demethylation [GO:0033169]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654] chromatin DNA binding [GO:0031490]; histone H3K9 demethylase activity [GO:0032454]; histone H3K9me/H3K9me2 demethylase activity [GO:0140683]; metal ion binding [GO:0046872]; transcription coregulator activity [GO:0003712] 0.96982 -4.9994 AGSSVDR 0 0 0 8.64551 0 0 0 0 0 0 0 0 9.24693 9.83232 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7LC44 ARC_HUMAN Activity-regulated cytoskeleton-associated protein (hArc) (Activity-regulated gene 3.1 protein homolog) (ARC/ARG3.1) (Arg3.1) ARC KIAA0278 Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; endoderm development [GO:0007492]; learning [GO:0007612]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; modulation of chemical synaptic transmission [GO:0050804]; mRNA transport [GO:0051028]; positive regulation of AMPA receptor activity [GO:2000969]; protein homooligomerization [GO:0051260]; regulation of cell morphogenesis [GO:0022604]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of long-term synaptic depression [GO:1900452]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; vesicle-mediated intercellular transport [GO:0110077] acrosomal vesicle [GO:0001669]; actin cytoskeleton [GO:0015629]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; extracellular vesicle [GO:1903561]; glutamatergic synapse [GO:0098978]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; neuronal ribonucleoprotein granule [GO:0071598]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic endosome [GO:0098845] mRNA binding [GO:0003729] 0.90783 -0.74234 EFLSHLEEYLR 0 0 0 10.6287 0 0 0 11.078 0 0 0 0 0 10.6165 0 10.2615 10.9635 0 0 9.98996 0 0 0 0 0 0 0 Q7LFL8 CXXC5_HUMAN CXXC-type zinc finger protein 5 (CF5) (Putative MAPK-activating protein PM08) (Putative NF-kappa-B-activating protein 102) (Retinoid-inducible nuclear factor) (RINF) CXXC5 HSPC195 TCCCIA00297 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA-binding transcription factor binding [GO:0140297]; methyl-CpG binding [GO:0008327]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270] 0.94057 -1.3274 RRINCEQCSSCR 0 0 0 0 0 9.26132 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7LGA3 HS2ST_HUMAN Heparan sulfate 2-O-sulfotransferase 1 (2-O-sulfotransferase) (2OST) (EC 2.8.2.-) HS2ST1 HS2ST KIAA0448 Homo sapiens (Human) "gene expression [GO:0010467]; heparan sulfate proteoglycan biosynthetic process, enzymatic modification [GO:0015015]; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; heparin metabolic process [GO:0030202]; ureteric bud formation [GO:0060676]" Golgi membrane [GO:0000139]; membrane [GO:0016020] heparan sulfate 2-O-sulfotransferase activity [GO:0004394] 0.55997 0.53145 FGDDYRPGLR 9.72848 9.77824 0 0 0 0 9.16154 9.3137 0 0 0 0 0 0 0 0 0 0 0 10.0415 0 0 0 0 0 0 0 Q7LGC8 CHST3_HUMAN Carbohydrate sulfotransferase 3 (EC 2.8.2.17) (EC 2.8.2.21) (Chondroitin 6-O-sulfotransferase 1) (C6ST-1) (Chondroitin 6-sulfotransferase) (C6ST) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0) (GST-0) CHST3 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate biosynthetic process [GO:0030206]; N-acetylglucosamine metabolic process [GO:0006044]; sulfur compound metabolic process [GO:0006790]; T cell homeostasis [GO:0043029] Golgi membrane [GO:0000139] chondroitin 6-sulfotransferase activity [GO:0008459]; N-acetylglucosamine 6-O-sulfotransferase activity [GO:0001517]; proteoglycan sulfotransferase activity [GO:0050698] 0.96821 -2.7719 CGPLNVTLAAEACRR 0 0 0 0 0 0 0 0 0 0 0 0 9.69954 9.84839 0 0 9.95316 0 0 0 0 0 0 0 0 0 0 Q7RTM1 OTOP1_HUMAN Proton channel OTOP1 (Otopetrin-1) (hOtop1) OTOP1 Homo sapiens (Human) biomineral tissue development [GO:0031214]; cellular response to insulin stimulus [GO:0032869]; detection of gravity [GO:0009590]; inner ear morphogenesis [GO:0042472]; negative regulation of type II interferon-mediated signaling pathway [GO:0060336]; proton transmembrane transport [GO:1902600] plasma membrane [GO:0005886] proton channel activity [GO:0015252] 0.95469 -1.5198 IDEKSLDESK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0455 0 0 0 0 0 0 0 0 0 0 0 Q7RTP6 MICA3_HUMAN [F-actin]-monooxygenase MICAL3 (EC 1.14.13.225) (Molecule interacting with CasL protein 3) (MICAL-3) MICAL3 KIAA0819 KIAA1364 Homo sapiens (Human) actin filament depolymerization [GO:0030042]; cell cycle [GO:0007049]; cell division [GO:0051301]; cytoskeleton organization [GO:0007010]; exocytosis [GO:0006887]; localization [GO:0051179] cell cortex [GO:0005938]; cell projection [GO:0042995]; cytosol [GO:0005829]; Flemming body [GO:0090543]; intercellular bridge [GO:0045171]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; spindle [GO:0005819] "actin binding [GO:0003779]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]" 0.9687 -6.5609 AFQELCDHLELKPKDYR 0 0 9.67666 0 0 9.93497 0 0 0 0 0 0 10.2423 0 0 0 0 0 0 0 0 0 0 0 10.0003 0 10.7188 Q7RTR0 NLRP9_HUMAN "NACHT, LRR and PYD domains-containing protein 9 (Nucleotide-binding oligomerization domain protein 6) (PYRIN and NACHT-containing protein 12)" NLRP9 NALP9 NOD6 PAN12 Homo sapiens (Human) defense response to virus [GO:0051607]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; positive regulation of interleukin-18 production [GO:0032741]; pyroptosis [GO:0070269]; regulation of inflammatory response [GO:0050727] canonical inflammasome complex [GO:0061702]; cytoplasm [GO:0005737] ATP binding [GO:0005524] 0.9698 -4.4038 ALKVFNFVR 0 0 0 9.65632 0 0 9.9544 10.3881 10.1482 9.4297 0 10.932 0 10.3947 10.0229 10.1075 0 9.99393 0 9.72272 0 9.49025 9.51477 0 0 0 0 Q7RTR2 NLRC3_HUMAN "NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3)" NLRC3 NOD3 Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] centriolar satellite [GO:0034451]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; perinuclear region of cytoplasm [GO:0048471] ATP binding [GO:0005524]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312] 0.63876 0.39685 GGGHPAR 0 0 0 0 0 0 9.31651 0 9.39774 0 8.47994 0 9.14428 0 0 0 0 0 0 0 0 0 9.22646 0 0 0 0 Q7RTR8 T2R42_HUMAN Taste receptor type 2 member 42 (T2R42) (Taste receptor type 2 member 55) (T2R55) TAS2R42 TAS2R55 Homo sapiens (Human) sensory perception of taste [GO:0050909] membrane [GO:0016020]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930] 0.96549 -2.2926 LSSLGSRDSSTEAHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0548 0 0 0 0 0 0 0 11.0443 0 Q7RTS6 OTOP2_HUMAN Proton channel OTOP2 (Otopetrin-2) OTOP2 Homo sapiens (Human) proton transmembrane transport [GO:1902600] plasma membrane [GO:0005886] proton channel activity [GO:0015252] 0.82946 0.20928 GPPGAEPHSTHPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.29561 0 0 0 0 Q7RTS7 K2C74_HUMAN "Keratin, type II cytoskeletal 74 (Cytokeratin-74) (CK-74) (Keratin-5c) (K5C) (Keratin-74) (K74) (Type II inner root sheath-specific keratin-K6irs4) (Type-II keratin Kb37)" KRT74 K6IRS4 KB37 KRT5C KRT6IRS4 Homo sapiens (Human) intermediate filament cytoskeleton organization [GO:0045104]; keratinization [GO:0031424] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; keratin filament [GO:0045095] keratin filament binding [GO:1990254]; structural constituent of skin epidermis [GO:0030280] 0.95265 -1.467 DLDLDSIIAEVR 0 0 0 0 0 0 0 0 0 0 10.2149 0 0 0 0 0 0 0 0 0 9.6985 0 0 0 0 0 0 Q7RTS9 DYM_HUMAN Dymeclin (Dyggve-Melchior-Clausen syndrome protein) DYM Homo sapiens (Human) bone development [GO:0060348]; Golgi organization [GO:0007030] cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; membrane [GO:0016020] enzyme binding [GO:0019899] 0.95869 -1.7841 QGVVALPKDR 0 0 0 0 0 0 0 0 0 0 10.028 9.54805 0 0 0 0 0 0 0 0 0 0 0 0 0 9.90851 0 Q7RTT3 SSX9_HUMAN Putative protein SSX9 SSX9P SSX9 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] 0.95299 -1.4821 SSEKIIYVYMK 0 0 0 0 0 0 0 0 0 9.74546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7RTT6 SSX6_HUMAN Putative protein SSX6 SSX6P SSX6 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] 0.59254 0.44937 IMPEKPAEEGSDSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1513 0 0 0 0 Q7RTU3 OLIG3_HUMAN Oligodendrocyte transcription factor 3 (Oligo3) (Class B basic helix-loop-helix protein 7) (bHLHb7) (Class E basic helix-loop-helix protein 20) (bHLHe20) OLIG3 BHLHB7 BHLHE20 Homo sapiens (Human) axon development [GO:0061564]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; sensory organ development [GO:0007423]; spinal cord motor neuron cell fate specification [GO:0021520]; spinal cord motor neuron migration [GO:0097476] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; E-box binding [GO:0070888]; protein dimerization activity [GO:0046983]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.67461 0.39371 AAGESSK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.55396 0 0 0 0 0 0 9.80126 0 0 0 0 0 9.62877 Q7RTU4 BHA09_HUMAN Class A basic helix-loop-helix protein 9 (bHLHa9) (Class F basic helix-loop-helix factor 42) (bHLHf42) BHLHA9 BHLHF42 Homo sapiens (Human) developmental process [GO:0032502]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.76409 0.28058 ILDYNEAFNALR 0 0 0 0 0 0 0 0 0 0 0 8.50962 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7RTY0 MOT13_HUMAN Monocarboxylate transporter 13 (MCT 13) (Solute carrier family 16 member 13) SLC16A13 MCT13 Homo sapiens (Human) monocarboxylic acid transport [GO:0015718] cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886] monocarboxylic acid transmembrane transporter activity [GO:0008028]; symporter activity [GO:0015293] 0.95474 -1.5017 VPLPKEGLEED 0 0 0 0 0 0 0 0 0 10.1163 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7RTY1 MOT9_HUMAN Monocarboxylate transporter 9 (MCT 9) (Solute carrier family 16 member 9) SLC16A9 C10orf36 MCT9 Homo sapiens (Human) carnitine transmembrane transport [GO:1902603]; creatine transmembrane transport [GO:0015881]; monocarboxylic acid transport [GO:0015718]; urate metabolic process [GO:0046415] plasma membrane [GO:0005886] carnitine transmembrane transporter activity [GO:0015226]; creatine transmembrane transporter activity [GO:0005308]; monocarboxylic acid transmembrane transporter activity [GO:0008028]; symporter activity [GO:0015293] 0.91753 -0.85316 IAPEDLPDKYSIYNEK 9.75659 0 0 0 0 0 0 0 9.01209 0 0 10.9374 0 0 0 0 0 10.9607 0 0 13.0004 0 0 0 0 10.6456 0 Q7RTY7 OVCH1_HUMAN Ovochymase-1 (EC 3.4.21.-) OVCH1 Homo sapiens (Human) proteolysis [GO:0006508] extracellular region [GO:0005576] metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252] 0.84759 0.16941 ACNTVLK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0755 10.2331 9.42253 9.58295 9.31234 0 0 0 0 0 0 0 0 9.40333 Q7RTY8 TMPS7_HUMAN Transmembrane protease serine 7 (EC 3.4.21.-) (Matriptase-3) TMPRSS7 Homo sapiens (Human) proteolysis [GO:0006508] plasma membrane [GO:0005886] serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236] 0.84192 0.18287 FQTSLSTLGIALK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1625 0 0 0 0 0 0 0 0 0 Q7RTY9 PRS41_HUMAN Serine protease 41 (EC 3.4.21.-) (Testis serine protease 1) (TESSP-1) PRSS41 TESSP1 Homo sapiens (Human) proteolysis [GO:0006508] extracellular region [GO:0005576]; intracellular organelle [GO:0043229]; plasma membrane [GO:0005886] serine-type endopeptidase activity [GO:0004252] 0.61742 0.41805 RPGGGGR 0 0 8.94597 9.10659 8.87184 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7RTZ1 OVCH2_HUMAN Ovochymase-2 (EC 3.4.21.-) (Oviductin) OVCH2 OVTN Homo sapiens (Human) fertilization [GO:0009566]; proteolysis [GO:0006508] extracellular region [GO:0005576] metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252] 0.87324 0.031535 KPMDYDIALLK 0 0 0 0 0 0 0 0 0 9.08868 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z2D5 PLPR4_HUMAN Phospholipid phosphatase-related protein type 4 (Brain-specific phosphatidic acid phosphatase-like protein 1) (Inactive 2-lysophosphatidate phosphatase PLPPR4) (Lipid phosphate phosphatase-related protein type 4) (Plasticity-related gene 1 protein) (PRG-1) PLPPR4 KIAA0455 LPPR4 PHP1 PRG1 Homo sapiens (Human) "axonogenesis [GO:0007409]; G protein-coupled receptor signaling pathway [GO:0007186]; inner ear development [GO:0048839]; lipid import into cell [GO:0140354]; phospholipid metabolic process [GO:0006644]; regulation of synaptic transmission, glutamatergic [GO:0051966]; signal transduction [GO:0007165]" glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839] lipid phosphatase activity [GO:0042577]; phosphatidate phosphatase activity [GO:0008195] 0.56448 0.49847 AGSSGGR 0 0 0 0 0 0 0 7.72683 0 0 8.95152 0 0 0 0 8.7148 0 0 0 0 0 0 0 0 0 0 0 Q7Z2E3 APTX_HUMAN Aprataxin (EC 3.6.1.71) (EC 3.6.1.72) (Forkhead-associated domain histidine triad-like protein) (FHA-HIT) APTX AXA1 Homo sapiens (Human) DNA ligation [GO:0006266]; regulation of protein stability [GO:0031647]; single strand break repair [GO:0000012] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; DNA 5'-adenosine monophosphate hydrolase activity [GO:0033699]; DNA-3'-diphospho-5'-guanosine diphosphatase [GO:0120108]; double-stranded DNA binding [GO:0003690]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mismatched DNA binding [GO:0030983]; phosphoglycolate phosphatase activity [GO:0008967]; phosphoprotein binding [GO:0051219]; polynucleotide 3'-phosphatase activity [GO:0046403]; single-strand break-containing DNA binding [GO:1990165]; single-stranded DNA binding [GO:0003697] 0.89878 -0.55932 ITDKKCSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0312 0 9.8334 9.56198 0 Q7Z2K6 ERMP1_HUMAN Endoplasmic reticulum metallopeptidase 1 (EC 3.4.-.-) (Felix-ina) ERMP1 FXNA KIAA1815 Homo sapiens (Human) cellular response to oxidative stress [GO:0034599]; endoplasmic reticulum unfolded protein response [GO:0030968]; proteolysis [GO:0006508] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] metal ion binding [GO:0046872]; metalloexopeptidase activity [GO:0008235] 0.96409 -2.4241 FLQPKHKTGNYK 0 0 0 0 0 0 0 0 0 10.874 0 9.22113 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z2K8 GRIN1_HUMAN G protein-regulated inducer of neurite outgrowth 1 (GRIN1) GPRIN1 KIAA1893 Homo sapiens (Human) neuron projection development [GO:0031175] growth cone [GO:0030426]; plasma membrane [GO:0005886] phosphoprotein binding [GO:0051219] 0.9636 -2.1445 ALGSARSPEGAR 0 0 0 0 0 0 0 0 0 9.2499 0 0 0 0 0 0 10.1204 0 0 0 8.48635 0 0 0 0 0 0 Q7Z2Q7 LRR70_HUMAN Leucine-rich repeat-containing protein 70 (Synleurin) LRRC70 UNQ1891/PRO4337 Homo sapiens (Human) positive regulation of response to cytokine stimulus [GO:0060760] plasma membrane [GO:0005886] 0.91766 -0.85869 LKASENSRENR 12.8235 12.6771 0 10.56 0 0 12.1038 12.4083 12.3558 0 11.4375 0 0 0 0 0 12.3129 0 0 0 0 0 0 0 0 0 0 Q7Z2T5 TRM1L_HUMAN TRMT1-like protein (EC 2.1.1.-) TRMT1L C1orf25 TRM1L MSTP070 Homo sapiens (Human) behavior [GO:0007610]; tRNA N2-guanine methylation [GO:0002940] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA binding [GO:0003723]; tRNA (guanine-N2-)-methyltransferase activity [GO:0004809]; tRNA binding [GO:0000049] 0.95937 -1.8627 FLCYLSQAGFRVSR 0 0 0 0 0 0 10.0425 11.3481 0 0 0 12.4334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z2W4 ZCCHV_HUMAN Zinc finger CCCH-type antiviral protein 1 (ADP-ribosyltransferase diphtheria toxin-like 13) (ARTD13) (Inactive Poly [ADP-ribose] polymerase 13) (PARP13) (Zinc finger CCCH domain-containing protein 2) (Zinc finger antiviral protein) (ZAP) ZC3HAV1 ZC3HDC2 PRO1677 Homo sapiens (Human) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of RIG-I signaling pathway [GO:1900246]; response to virus [GO:0009615] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] cadherin binding [GO:0045296]; metal ion binding [GO:0046872]; RNA binding [GO:0003723] 0.92017 -0.91401 ASLEDAPVDDLTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.85114 0 0 0 0 0 0 0 11.2574 Q7Z2W7 TRPM8_HUMAN Transient receptor potential cation channel subfamily M member 8 (Long transient receptor potential channel 6) (LTrpC-6) (LTrpC6) (Transient receptor potential p8) (Trp-p8) TRPM8 LTRPC6 TRPP8 Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; intracellular calcium ion homeostasis [GO:0006874]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to cold [GO:0009409]; thermoception [GO:0050955] endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; membrane raft [GO:0045121]; plasma membrane [GO:0005886] calcium channel activity [GO:0005262]; identical protein binding [GO:0042802]; ligand-gated calcium channel activity [GO:0099604] 0.9201 -1.1426 MSFRAAR 0 0 0 0 0 0 0 0 0 9.08783 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z2W9 RM21_HUMAN "Large ribosomal subunit protein bL21m (39S ribosomal protein L21, mitochondrial) (L21mt) (MRP-L21)" MRPL21 Homo sapiens (Human) mitochondrial translation [GO:0032543] mitochondrial inner membrane [GO:0005743]; mitochondrial large ribosomal subunit [GO:0005762]; mitochondrion [GO:0005739] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.89721 -0.67067 IIMRFRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4594 10.3334 10.353 0 9.13211 0 0 0 0 Q7Z2Y5 NRK_HUMAN Nik-related protein kinase (EC 2.7.11.1) NRK Homo sapiens (Human) protein phosphorylation [GO:0006468] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96986 -5.2242 DIKNERHVVESLTR 9.06026 9.66736 0 0 0 11.5501 0 9.34769 0 11.0825 0 9.88464 8.59712 8.41397 0 0 11.7074 0 0 0 0 0 0 0 0 0 0 Q7Z2Y8 GVIN1_HUMAN Interferon-induced very large GTPase 1 (Interferon-induced very large GTPase pseudogene 1) GVINP1 GVIN1 VLIG1 Homo sapiens (Human) cytosol [GO:0005829]; nucleus [GO:0005634] GTP binding [GO:0005525] 0.96965 -5.1079 EARVFLEDVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.9853 0 0 0 0 0 0 11.2267 0 10.1635 Q7Z2Z1 TICRR_HUMAN "Treslin (TopBP1-interacting checkpoint and replication regulator) (TopBP1-interacting, replication-stimulating protein)" TICRR C15orf42 Homo sapiens (Human) DNA repair [GO:0006281]; DNA replication [GO:0006260]; mitotic DNA replication checkpoint signaling [GO:0033314]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; regulation of DNA-templated DNA replication initiation [GO:0030174]; response to ionizing radiation [GO:0010212] cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682] 0.96955 -5.6151 AEEPAQK 0 0 0 0 0 10.3821 0 0 0 0 0 9.37569 0 0 0 0 0 0 9.38321 9.34693 9.40035 11.374 9.70025 8.19957 0 0 0 Q7Z2Z2 EFL1_HUMAN Elongation factor-like GTPase 1 (Elongation factor Tu GTP-binding domain-containing protein 1) (Elongation factor-like 1) (Protein FAM42A) EFL1 EFTUD1 FAM42A Homo sapiens (Human) cytosolic ribosome assembly [GO:0042256]; GTP metabolic process [GO:0046039] cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746] 0.93183 -1.2685 EARHSDPK 0 0 0 0 0 0 0 8.52841 0 0 0 0 0 8.92342 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z333 SETX_HUMAN Probable helicase senataxin (EC 3.6.4.-) (Amyotrophic lateral sclerosis 4 protein) (SEN1 homolog) (Senataxin) SETX ALS4 KIAA0625 SCAR1 Homo sapiens (Human) "cell differentiation [GO:0030154]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; cellular response to retinoic acid [GO:0071300]; circadian rhythm [GO:0007623]; DNA damage response [GO:0006974]; DNA recombination [GO:0006310]; DNA-templated transcription termination [GO:0006353]; double-strand break repair [GO:0006302]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; mRNA splice site selection [GO:0006376]; negative regulation of apoptotic process [GO:0043066]; nervous system development [GO:0007399]; positive regulation of DNA-templated transcription initiation [GO:2000144]; positive regulation of neuron projection development [GO:0010976]; positive regulation of RNA splicing [GO:0033120]; positive regulation of termination of DNA-templated transcription [GO:0060566]; positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled [GO:2000806]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein kinase B signaling [GO:0043491]; RNA processing [GO:0006396]; spermatogenesis [GO:0007283]; termination of RNA polymerase II transcription [GO:0006369]" "axon [GO:0030424]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; growth cone [GO:0030426]; intercellular bridge [GO:0045171]; nuclear body [GO:0016604]; nuclear chromosome [GO:0000228]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]" ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; transcription termination site sequence-specific DNA binding [GO:0001147] 0.9692 -3.0595 ALCRGGREIQR 10.6209 0 0 9.04174 9.27237 11.3288 0 10.6924 0 10.6784 0 10.8327 8.71812 0 0 0 0 9.71706 8.86833 9.04333 9.07395 9.55607 10.8636 9.79264 0 9.03521 0 Q7Z353 HDX_HUMAN Highly divergent homeobox HDX CXorf43 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.92386 -1.0221 AENQSTTLPGPGR 0 0 0 0 0 0 0 8.94014 0 0 0 0 0 0 0 0 0 0 0 0 0 9.5255 0 0 0 0 0 Q7Z392 TPC11_HUMAN Trafficking protein particle complex subunit 11 TRAPPC11 C4orf41 Homo sapiens (Human) constitutive secretory pathway [GO:0045054]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; regulation of protein complex stability [GO:0061635]; vesicle tethering [GO:0099022] cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; TRAPP complex [GO:0030008]; TRAPPIII protein complex [GO:1990072] 0.9697 -5.0476 CRPKRTSYEWYIPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0639 0 0 0 10.8254 0 0 Q7Z398 ZN550_HUMAN Zinc finger protein 550 ZNF550 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.89967 -0.69044 HNRTHTGEKPFECK 0 0 0 0 0 0 0 0 0 0 0 10.0171 0 0 0 0 11.0843 0 0 0 0 0 0 0 0 0 0 Q7Z3B0 SIM15_HUMAN Small integral membrane protein 15 SMIM15 C5orf43 Homo sapiens (Human) membrane [GO:0016020] 0.95592 -1.5878 LAKMIEAR 0 10.957 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z3B3 KANL1_HUMAN KAT8 regulatory NSL complex subunit 1 (MLL1/MLL complex subunit KANSL1) (MSL1 homolog 1) (hMSL1v1) (NSL complex protein NSL1) (Non-specific lethal 1 homolog) KANSL1 CENP-36 KIAA1267 MSL1V1 NSL1 Homo sapiens (Human) chromatin organization [GO:0006325]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of histone H3-K4 methylation [GO:0051571]; regulation of dosage compensation by inactivation of X chromosome [GO:1900095] histone acetyltransferase complex [GO:0000123]; kinetochore [GO:0000776]; MLL1 complex [GO:0071339]; NSL complex [GO:0044545]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] histone acetyltransferase binding [GO:0035035] 0.8125 0.22263 LPNLESLRPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4315 0 0 0 0 0 0 0 0 0 0 0 Q7Z3C6 ATG9A_HUMAN Autophagy-related protein 9A (APG9-like 1) (mATG9) ATG9A APG9L1 Homo sapiens (Human) autophagosome assembly [GO:0000045]; autophagy of mitochondrion [GO:0000422]; bone morphogenesis [GO:0060349]; late nucleophagy [GO:0044805]; positive regulation of necrotic cell death [GO:0010940]; protein localization to phagophore assembly site [GO:0034497] autophagosome [GO:0005776]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; membrane [GO:0016020]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; phagophore assembly site [GO:0000407]; phagophore assembly site membrane [GO:0034045]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; trans-Golgi network [GO:0005802] phospholipid scramblase activity [GO:0017128] 0.88867 -0.40338 ELTELDIYHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.63008 0 0 10.3318 0 Q7Z3D6 GLUCM_HUMAN "D-glutamate cyclase, mitochondrial (EC 4.2.1.48)" DGLUCY C14orf159 UNQ2439/PRO5000 Homo sapiens (Human) glutamate metabolic process [GO:0006536] mitochondrial matrix [GO:0005759] D-glutamate cyclase activity [GO:0047820] 0.90745 -0.73658 APGDQAWTQALPSVIK 0 0 0 9.42465 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z3E1 PARPT_HUMAN Protein mono-ADP-ribosyltransferase TIPARP (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (Poly [ADP-ribose] polymerase 7) (PARP-7) (TCDD-inducible poly [ADP-ribose] polymerase) TIPARP PARP7 Homo sapiens (Human) androgen metabolic process [GO:0008209]; cellular response to organic cyclic compound [GO:0071407]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; kidney development [GO:0001822]; negative regulation of gene expression [GO:0010629]; nitrogen compound metabolic process [GO:0006807]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of protein catabolic process [GO:0045732]; post-embryonic development [GO:0009791]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; smooth muscle tissue development [GO:0048745]; vasculogenesis [GO:0001570] nucleus [GO:0005634] cis-regulatory region sequence-specific DNA binding [GO:0000987]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+- protein-cysteine ADP-ribosyltransferase activity [GO:0140803]; NAD+-protein ADP-ribosyltransferase activity [GO:1990404]; nucleotidyltransferase activity [GO:0016779] 0.92739 -1.2048 GVHFMFLAK 9.14853 0 0 9.49825 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7896 0 9.98085 0 0 0 0 11.902 0 0 Q7Z3E2 CC186_HUMAN Coiled-coil domain-containing protein 186 (CTCL tumor antigen HD-CL-01/L14-2) CCDC186 C10orf118 Homo sapiens (Human) insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; response to bacterium [GO:0009617]; vesicle cytoskeletal trafficking [GO:0099518] trans-Golgi network [GO:0005802] small GTPase binding [GO:0031267] 0.96157 -2.5922 ALSTQVEELK 0 0 10.691 0 0 0 0 10.667 0 0 0 0 0 0 0 0 0 10.3172 0 9.84119 9.71959 0 0 0 0 10.0779 0 Q7Z3E5 ARMC9_HUMAN LisH domain-containing protein ARMC9 (Armadillo repeat-containing protein 9) (Melanoma/melanocyte-specific tumor antigen KU-MEL-1) (NS21) ARMC9 KIAA1868 Homo sapiens (Human) cilium assembly [GO:0060271]; positive regulation of smoothened signaling pathway [GO:0045880] centriole [GO:0005814]; ciliary basal body [GO:0036064]; ciliary tip [GO:0097542]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062] 0.92042 -0.92198 IKGKPLCK 10.9703 10.881 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.02934 0 9.637 0 0 8.99016 0 0 0 Q7Z3G6 PRIC2_HUMAN Prickle-like protein 2 PRICKLE2 Homo sapiens (Human) "Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" cytoplasm [GO:0005737]; nuclear membrane [GO:0031965] zinc ion binding [GO:0008270] 0.76517 0.28319 CAACDEIIFADECTEAEGR 10.7289 0 0 0 0 0 0 11.0741 0 0 0 0 0 0 0 0 10.0885 0 0 0 0 0 0 0 0 0 0 Q7Z3I7 ZN572_HUMAN Zinc finger protein 572 ZNF572 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of cytokine production [GO:0001817]; regulation of immune system process [GO:0002682] nucleus [GO:0005634] DNA binding [GO:0003677]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872] 0.96489 -2.2848 ADKLKEKPSEWSK 0 10.4841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z3J2 VP35L_HUMAN VPS35 endosomal protein-sorting factor-like (Esophageal cancer-associated protein) VPS35L C16orf62 101F10.2 Homo sapiens (Human) endocytic recycling [GO:0032456]; Golgi to plasma membrane transport [GO:0006893]; protein transport [GO:0015031] endosome [GO:0005768]; ficolin-1-rich granule membrane [GO:0101003]; plasma membrane [GO:0005886] 0.96733 -2.797 AVFPWHSRNR 0 0 0 0 0 0 0 0 8.6074 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z3K3 POGZ_HUMAN Pogo transposable element with ZNF domain (Suppressor of hairy wing homolog 5) (Zinc finger protein 280E) (Zinc finger protein 635) POGZ KIAA0461 SUHW5 ZNF280E ZNF635 Nbla00003 Homo sapiens (Human) cell division [GO:0051301]; double-strand break repair via homologous recombination [GO:0000724]; kinetochore assembly [GO:0051382]; mitotic sister chromatid cohesion [GO:0007064]; regulation of gene expression [GO:0010468] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.96767 -2.89 AVRKMSVMGR 10.9346 0 0 0 0 0 9.58118 0 12.163 0 11.6874 0 0 0 0 10.5483 0 0 0 0 0 8.39571 0 9.702 0 11.7674 0 Q7Z3S7 CA2D4_HUMAN Voltage-dependent calcium channel subunit alpha-2/delta-4 (Voltage-gated calcium channel subunit alpha-2/delta-4) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-4; Voltage-dependent calcium channel subunit delta-4] CACNA2D4 Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; detection of light stimulus involved in visual perception [GO:0050908]; regulation of monoatomic ion transmembrane transport [GO:0034765] voltage-gated calcium channel complex [GO:0005891] metal ion binding [GO:0046872]; voltage-gated calcium channel activity [GO:0005245] 0.95406 -1.5243 MKWIACNNK 0 0 0 0 0 0 9.72945 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z3S9 NT2NA_HUMAN Notch homolog 2 N-terminal-like protein A (Notch homolog 2 N-terminal-like protein) NOTCH2NLA N2N NOTCH2NL Homo sapiens (Human) cell differentiation [GO:0030154]; cerebral cortex development [GO:0021987]; Notch signaling pathway [GO:0007219]; positive regulation of Notch signaling pathway [GO:0045747] cytoplasm [GO:0005737]; extracellular region [GO:0005576] calcium ion binding [GO:0005509]; Notch binding [GO:0005112] 0.38435 0.7191 CVTYHNGTGYCK 10.5826 10.4683 10.8207 0 0 0 10.2291 10.3806 10.268 11.4394 11.3346 11.2659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z3U7 MON2_HUMAN Protein MON2 homolog (Protein SF21) MON2 KIAA1040 SF21 Homo sapiens (Human) Golgi to endosome transport [GO:0006895]; protein transport [GO:0015031] cytosol [GO:0005829]; early endosome membrane [GO:0031901]; extracellular exosome [GO:0070062] 0.88317 -0.07062 AVAVESIHR 0 13.8785 0 0 10.4609 10.0937 12.7653 0 0 0 0 11.2099 0 11.7943 11.943 13.2228 13.577 0 0 0 9.95497 0 0 0 0 11.0651 0 Q7Z3V4 UBE3B_HUMAN Ubiquitin-protein ligase E3B (EC 2.3.2.26) (HECT-type ubiquitin transferase E3B) UBE3B Homo sapiens (Human) protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] ubiquitin protein ligase activity [GO:0061630] 0.96947 -3.5001 ERERAAVVIQAHVR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2755 0 10.6277 0 0 0 0 0 9.11803 0 0 9.0413 11.6595 10.5539 Q7Z3Y8 K1C27_HUMAN "Keratin, type I cytoskeletal 27 (Cytokeratin-27) (CK-27) (Keratin-25C) (K25C) (Keratin-27) (K27) (Type I inner root sheath-specific keratin-K25irs3)" KRT27 KRT25C Homo sapiens (Human) epithelial cell differentiation [GO:0030855]; hair follicle morphogenesis [GO:0031069]; intermediate filament organization [GO:0045109] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882] structural molecule activity [GO:0005198] 0.96959 -3.0923 ALEEANADLEQK 0 11.6736 0 0 0 0 8.9002 0 0 0 0 0 0 0 0 0 0 0 0 0 9.24358 0 0 0 0 0 0 Q7Z3Z0 K1C25_HUMAN "Keratin, type I cytoskeletal 25 (Cytokeratin-25) (CK-25) (Keratin-25) (K25) (Keratin-25A) (K25A) (Type I inner root sheath-specific keratin-K25irs1)" KRT25 KRT25A Homo sapiens (Human) cytoskeleton organization [GO:0007010]; epithelial cell differentiation [GO:0030855]; hair cycle [GO:0042633]; hair follicle morphogenesis [GO:0031069]; intermediate filament organization [GO:0045109] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; keratin filament [GO:0045095] protein heterodimerization activity [GO:0046982]; structural molecule activity [GO:0005198] 0.84795 0.17174 DAEAWFNEK 0 0 0 0 0 0 0 10.8605 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z3Z3 PIWL3_HUMAN Piwi-like protein 3 PIWIL3 Homo sapiens (Human) cell differentiation [GO:0030154]; meiotic cell cycle [GO:0051321]; regulation of translation [GO:0006417]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; nucleus [GO:0005634]; P granule [GO:0043186] piRNA binding [GO:0034584]; RNA endonuclease activity [GO:0004521] 0.95447 -1.6161 ELEICLK 0 0 9.71917 0 0 0 0 0 0 11.7607 0 0 0 0 0 0 0 0 0 0 0 0 0 9.26959 0 0 9.95997 Q7Z3Z4 PIWL4_HUMAN Piwi-like protein 4 PIWIL4 HIWI2 PIWI Homo sapiens (Human) cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; epithelial structure maintenance [GO:0010669]; meiotic cell cycle [GO:0051321]; negative regulation of transposition [GO:0010529]; regulation of translation [GO:0006417]; RNA-mediated gene silencing [GO:0031047]; secondary piRNA processing [GO:0140965]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P granule [GO:0043186]; piP-body [GO:0071547] piRNA binding [GO:0034584]; RNA endonuclease activity [GO:0004521] 0.80357 0.23829 SLMVVGIDVCK 0 0 0 0 0 0 10.9535 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z401 MYCPP_HUMAN C-myc promoter-binding protein (DENN domain-containing protein 4A) DENND4A IRLB MYCPBP Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of Rab protein signal transduction [GO:0032483] cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; nucleus [GO:0005634] DNA binding [GO:0003677]; guanyl-nucleotide exchange factor activity [GO:0005085] 0.96866 -8.0139 EYKMAYDR 0 0 0 0 0 0 0 0 0 9.71223 8.49269 0 0 0 0 8.58116 0 0 0 0 0 0 0 0 0 0 0 Q7Z402 TMC7_HUMAN Transmembrane channel-like protein 7 TMC7 Homo sapiens (Human) plasma membrane [GO:0005886] mechanosensitive monoatomic ion channel activity [GO:0008381] 0.92617 -0.95906 IAERTSEETIRIYSLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.84583 0 0 0 0 0 0 0 0 Q7Z403 TMC6_HUMAN Transmembrane channel-like protein 6 (Epidermodysplasia verruciformis protein 1) (Protein LAK-4) TMC6 EVER1 EVIN1 Homo sapiens (Human) cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821] mechanosensitive monoatomic ion channel activity [GO:0008381] 0.96403 -2.4372 IFLINKLHSIYER 12.576 12.2295 12.3897 0 0 0 11.7221 11.9253 12.0565 12.2765 12.5063 12.5837 0 0 0 0 11.6711 0 0 9.78111 0 0 0 0 0 0 0 Q7Z404 TMC4_HUMAN Transmembrane channel-like protein 4 TMC4 Homo sapiens (Human) extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] mechanosensitive monoatomic ion channel activity [GO:0008381] 0.89165 -0.50593 AVALTSTKPAL 0 0 9.32771 0 0 0 0 0 0 0 0 9.86569 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z406 MYH14_HUMAN "Myosin-14 (Myosin heavy chain 14) (Myosin heavy chain, non-muscle IIc) (Non-muscle myosin heavy chain IIc) (NMHC II-C)" MYH14 KIAA2034 FP17425 Homo sapiens (Human) actin filament-based movement [GO:0030048]; actomyosin structure organization [GO:0031032]; mitochondrion morphogenesis [GO:0070584]; neuronal action potential [GO:0019228]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal muscle contraction [GO:0003009]; skeletal muscle tissue development [GO:0007519]; vocalization behavior [GO:0071625] actomyosin [GO:0042641]; brush border [GO:0005903]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; growth cone [GO:0030426]; membrane [GO:0016020]; myosin filament [GO:0032982]; myosin II complex [GO:0016460]; myosin II filament [GO:0097513]; stress fiber [GO:0001725] actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; microfilament motor activity [GO:0000146] 0.96839 -8.8262 AAREAEALTQR 0 0 11.7045 0 10.5307 0 9.52393 12.0887 9.6339 9.70094 0 10.2712 0 0 9.41971 0 0 9.52953 0 0 0 0 10.3982 10.5859 11.0204 0 9.02589 Q7Z407 CSMD3_HUMAN CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3) CSMD3 KIAA1894 Homo sapiens (Human) regulation of dendrite development [GO:0050773] plasma membrane [GO:0005886] 0.91986 -0.91291 ESCFDPGNIMNGTRLGMDYK 0 0 9.78251 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z408 CSMD2_HUMAN CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2) CSMD2 KIAA1884 Homo sapiens (Human) plasma membrane [GO:0005886] 0.95989 -1.9825 GFDLSELER 10.2143 0 0 0 9.04985 9.21822 8.48127 9.88199 0 0 10.393 0 0 10.8951 0 0 0 9.98783 8.87958 0 0 9.28566 0 0 0 0 0 Q7Z417 NUFP2_HUMAN FMR1-interacting protein NUFIP2 (82 kDa FMRP-interacting protein) (82-FIP) (Cell proliferation-inducing gene 1 protein) (FMRP-interacting protein 2) (Nuclear FMR1-interacting protein 2) NUFIP2 KIAA1321 PIG1 Homo sapiens (Human) cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; membrane [GO:0016020]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; polysomal ribosome [GO:0042788] RNA binding [GO:0003723] 0.96345 -2.6527 ISYASKVK 0 0 0 0 0 9.63303 0 0 0 11.2992 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z429 LFG1_HUMAN Protein lifeguard 1 (Glutamate [NMDA] receptor-associated protein 1) (NMDA receptor glutamate-binding subunit) (Putative MAPK-activating protein PM02) (Transmembrane BAX inhibitor motif-containing protein 3) GRINA LFG1 NMDARA1 TMBIM3 Homo sapiens (Human) endoplasmic reticulum calcium ion homeostasis [GO:0032469]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236] endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; membrane [GO:0016020] transmembrane transporter binding [GO:0044325] 0.95925 -1.7161 SIRQAFIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.07858 0 0 0 0 0 0 Q7Z434 MAVS_HUMAN Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Putative NF-kappa-B-activating protein 031N) (Virus-induced-signaling adapter) (VISA) MAVS IPS1 KIAA1271 VISA Homo sapiens (Human) activation of innate immune response [GO:0002218]; antiviral innate immune response [GO:0140374]; cellular response to exogenous dsRNA [GO:0071360]; cytosolic pattern recognition receptor signaling pathway [GO:0002753]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; positive regulation of chemokine (C-C motif) ligand 5 production [GO:0071651]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of IP-10 production [GO:0071660]; positive regulation of myeloid dendritic cell cytokine production [GO:0002735]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of response to cytokine stimulus [GO:0060760]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein localization to mitochondrion [GO:0070585]; regulation of peroxisome organization [GO:1900063]; signal transduction [GO:0007165]; type I interferon-mediated signaling pathway [GO:0060337] mitochondrial membrane [GO:0031966]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; peroxisomal membrane [GO:0005778]; ubiquitin ligase complex [GO:0000151] CARD domain binding [GO:0050700]; identical protein binding [GO:0042802]; molecular adaptor activity [GO:0060090]; molecular condensate scaffold activity [GO:0140693]; molecular function activator activity [GO:0140677]; protein kinase binding [GO:0019901]; RIG-I binding [GO:0039552]; signaling adaptor activity [GO:0035591] 0.91143 -0.75164 AGMVPSKVPTSMVLTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7392 0 0 Q7Z442 PK1L2_HUMAN Polycystin-1-like protein 2 (Polycystin-1L2) (PC1-like 2 protein) (Polycystic kidney disease protein 1-like 2) PKD1L2 KIAA1879 PC1L2 Homo sapiens (Human) detection of mechanical stimulus [GO:0050982] membrane [GO:0016020] calcium channel activity [GO:0005262]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246] 0.38246 0.72019 AGDTQQTQAMAK 8.66406 0 0 8.55639 0 0 8.3137 8.23998 0 0 9.29827 0 0 0 0 0 0 10.6919 12.0466 0 11.143 0 0 9.33675 0 10.0466 10.7915 Q7Z460 CLAP1_HUMAN CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) (Multiple asters homolog 1) (Protein Orbit homolog 1) (hOrbit1) CLASP1 KIAA0622 MAST1 Homo sapiens (Human) "astral microtubule organization [GO:0030953]; cell division [GO:0051301]; establishment of epithelial cell polarity [GO:0090162]; establishment of mitotic spindle localization [GO:0040001]; establishment of spindle orientation [GO:0051294]; establishment or maintenance of cell polarity [GO:0007163]; exit from mitosis [GO:0010458]; Golgi organization [GO:0007030]; microtubule anchoring [GO:0034453]; microtubule bundle formation [GO:0001578]; microtubule cytoskeleton organization [GO:0000226]; microtubule nucleation [GO:0007020]; microtubule organizing center organization [GO:0031023]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of exocytosis [GO:0045921]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of microtubule polymerization [GO:0031116]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of focal adhesion assembly [GO:0051893]; regulation of gastrulation [GO:0010470]; regulation of microtubule cytoskeleton organization [GO:0070507]; vesicle targeting [GO:0006903]" basal cortex [GO:0045180]; cell cortex [GO:0005938]; centrosomal corona [GO:0031592]; centrosome [GO:0005813]; cortical microtubule cytoskeleton [GO:0030981]; cytoplasmic microtubule [GO:0005881]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; kinetochore [GO:0000776]; kinetochore microtubule [GO:0005828]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; microtubule plus-end [GO:0035371]; mitotic spindle [GO:0072686]; spindle microtubule [GO:0005876] dystroglycan binding [GO:0002162]; kinetochore binding [GO:0043515]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010] 0.91527 -0.8072 EAEHLYHTLESSYQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4467 10.7883 0 0 0 0 0 0 0 0 11.0609 Q7Z465 BNIPL_HUMAN Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein BNIPL Homo sapiens (Human) apoptotic process [GO:0006915]; negative regulation of cell population proliferation [GO:0008285]; regulation of growth rate [GO:0040009] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] identical protein binding [GO:0042802] 0.66115 0.39465 DLHGSGGT 0 0 0 0 0 7.81372 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z478 DHX29_HUMAN ATP-dependent RNA helicase DHX29 (EC 3.6.4.13) (DEAH box protein 29) (Nucleic acid helicase DDXx) DHX29 DDX29 Homo sapiens (Human) formation of translation preinitiation complex [GO:0001731]; positive regulation of translational initiation [GO:0045948]; ribosome assembly [GO:0042255] cytosolic small ribosomal subunit [GO:0022627]; eukaryotic 43S preinitiation complex [GO:0016282] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; cadherin binding [GO:0045296]; helicase activity [GO:0004386]; ribonucleoside triphosphate phosphatase activity [GO:0017111]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; translation activator activity [GO:0008494]; translation initiation factor activity [GO:0003743] 0.9582 -1.681 ISHQQNER 0 0 0 0 0 0 0 0 9.56923 0 0 0 0 0 0 0 8.59025 0 0 0 0 0 9.79219 0 0 0 0 Q7Z494 NPHP3_HUMAN Nephrocystin-3 NPHP3 KIAA2000 Homo sapiens (Human) "atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055]" ciliary base [GO:0097546]; ciliary inversin compartment [GO:0097543]; cilium [GO:0005929]; cytosol [GO:0005829]; extracellular region [GO:0005576] 0.96866 -5.7903 EAKLDTENKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8364 9.52644 0 0 0 0 0 0 0 0 0 0 Q7Z4G1 COMD6_HUMAN COMM domain-containing protein 6 COMMD6 MSTP076 Homo sapiens (Human) negative regulation of NF-kappaB transcription factor activity [GO:0032088] cytoplasm [GO:0005737]; nucleus [GO:0005634] NF-kappaB binding [GO:0051059] 0.56542 0.48684 EASSEPPLDAK 0 0 0 0 0 0 0 0 0 0 0 11.4055 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z4G4 TRM11_HUMAN tRNA (guanine(10)-N2)-methyltransferase homolog (EC 2.1.1.-) (tRNA guanosine-2'-O-methyltransferase TRM11 homolog) TRMT11 C6orf75 MDS024 Homo sapiens (Human) cytoplasm [GO:0005737] tRNA (guanine-N2-)-methyltransferase activity [GO:0004809]; tRNA binding [GO:0000049] 0.96283 -2.1646 LSSHTSRR 0 0 0 12.2813 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z4H4 ADM2_HUMAN Protein ADM2 (Intermedin) [Cleaved into: Adrenomedullin-2 (AM2) (Intermedin-long) (IMDL); Intermedin-short (IMDS)] ADM2 AM2 Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; angiogenesis [GO:0001525]; digestion [GO:0007586]; feeding behavior [GO:0007631]; negative regulation of blood pressure [GO:0045776]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of heart rate [GO:0010460]; protein phosphorylation [GO:0006468]; regulation of systemic arterial blood pressure [GO:0003073] extracellular region [GO:0005576] hormone activity [GO:0005179]; protein-containing complex binding [GO:0044877] 0.88296 -0.29928 DGGRQHSGPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4668 0 0 Q7Z4H7 HAUS6_HUMAN HAUS augmin-like complex subunit 6 HAUS6 DGT6 FAM29A KIAA1574 Homo sapiens (Human) cell division [GO:0051301]; centrosome cycle [GO:0007098]; microtubule cytoskeleton organization [GO:0000226]; spindle assembly [GO:0051225] centrosome [GO:0005813]; cytosol [GO:0005829]; HAUS complex [GO:0070652]; mitotic spindle microtubule [GO:1990498] microtubule binding [GO:0008017] 0.95476 -1.6135 KAIEMEENR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5022 0 0 0 0 0 Q7Z4H8 PLGT3_HUMAN Protein O-glucosyltransferase 3 (EC 2.4.1.-) (KDEL motif-containing protein 2) (Protein O-xylosyltransferase POGLUT3) (EC 2.4.2.-) POGLUT3 KDELC2 UNQ1904/PRO4350 Homo sapiens (Human) protein O-linked glycosylation via serine [GO:0018242] endomembrane system [GO:0012505]; endoplasmic reticulum lumen [GO:0005788] EGF-domain serine glucosyltransferase activity [GO:0140561]; EGF-domain serine xylosyltransferase activity [GO:0140562]; glucosyltransferase activity [GO:0046527]; UDP-glucosyltransferase activity [GO:0035251]; UDP-xylosyltransferase activity [GO:0035252] 0.9638 -2.2136 SLSPKELVR 0 0 0 9.4165 0 9.54469 0 0 0 0 0 0 0 0 0 11.2052 0 0 0 0 0 0 0 0 0 0 0 Q7Z4I7 LIMS2_HUMAN LIM and senescent cell antigen-like-containing domain protein 2 (LIM-like protein 2) (Particularly interesting new Cys-His protein 2) (PINCH-2) LIMS2 PINCH2 Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cell-cell junction organization [GO:0045216]; cholangiocyte proliferation [GO:1990705]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cholangiocyte proliferation [GO:1904055]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of neural precursor cell proliferation [GO:2000178]; neural precursor cell proliferation [GO:0061351]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026] cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; plasma membrane [GO:0005886] metal ion binding [GO:0046872] 0.93167 -1.2721 HLCRPCHNR 0 0 0 0 0 0 0 0 0 11.1679 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z4J2 GL6D1_HUMAN Putative glycosyltransferase 6 domain-containing protein 1 (EC 2.4.1.-) (Galactosyltransferase family 6 domain-containing 1) GLT6D1 GLTDC1 GT6M7 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259] Golgi apparatus [GO:0005794]; membrane [GO:0016020]; vesicle [GO:0031982] glycosyltransferase activity [GO:0016757]; hexosyltransferase activity [GO:0016758] 0.95954 -1.7294 LSDWFHPRK 11.9968 0 0 0 0 0 11.5896 0 11.5081 0 0 0 9.16232 11.2851 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z4K8 TRI46_HUMAN "Tripartite motif-containing protein 46 (Gene Y protein) (GeneY) (Tripartite, fibronectin type-III and C-terminal SPRY motif protein)" TRIM46 TRIFIC Homo sapiens (Human) anterograde synaptic vesicle transport [GO:0048490]; axonogenesis [GO:0007409]; microtubule bundle formation [GO:0001578]; negative regulation of axon extension [GO:0030517]; neuron migration [GO:0001764]; positive regulation of anterograde dense core granule transport [GO:1901953]; protein localization to axon [GO:0099612]; regulation of protein localization [GO:0032880] axon cytoplasm [GO:1904115]; axon initial segment [GO:0043194]; cytoskeleton [GO:0005856]; main axon [GO:0044304]; proximal neuron projection [GO:1990769] zinc ion binding [GO:0008270] 0.92041 -0.9216 GLGAVLEEK 0 0 0 0 9.4223 0 0 0 0 0 0 0 0 0 0 0 9.44272 9.07079 0 0 0 0 0 0 0 0 0 Q7Z4L5 TT21B_HUMAN Tetratricopeptide repeat protein 21B (TPR repeat protein 21B) (Intraflagellar transport 139 homolog) TTC21B IFT139 KIAA1992 Nbla10696 Homo sapiens (Human) Bergmann glial cell differentiation [GO:0060020]; cerebellar Purkinje cell differentiation [GO:0021702]; cilium assembly [GO:0060271]; forebrain dorsal/ventral pattern formation [GO:0021798]; intraciliary retrograde transport [GO:0035721]; negative regulation of eating behavior [GO:1903999]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; protein localization to cilium [GO:0061512]; protein localization to non-motile cilium [GO:0097499]; regulation of intraciliary retrograde transport [GO:1905799]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription by RNA polymerase II [GO:0006357]; smoothened signaling pathway [GO:0007224]; ventricular system development [GO:0021591] ciliary tip [GO:0097542]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; intraciliary transport particle A [GO:0030991] chromatin binding [GO:0003682] 0.96968 -3.1032 DGTLASKMGK 0 0 0 0 0 0 0 0 0 0 0 9.91284 0 0 0 0 0 0 0 0 0 0 10.2596 8.87101 10.2448 0 0 Q7Z4L9 PPR42_HUMAN Protein phosphatase 1 regulatory subunit 42 (Leucine-rich repeat-containing protein 67) PPP1R42 LRRC67 Homo sapiens (Human) centrosome [GO:0005813]; cytoplasm [GO:0005737]; manchette [GO:0002177]; microtubule cytoskeleton [GO:0015630]; microtubule organizing center [GO:0005815] actin binding [GO:0003779]; dynein complex binding [GO:0070840]; tubulin binding [GO:0015631] 0.58237 0.47063 ITHINFSDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0183 0 9.84119 0 0 0 0 0 0 0 Q7Z4M0 RE114_HUMAN Meiotic recombination protein REC114 REC114 C15orf60 Homo sapiens (Human) DNA recombination [GO:0006310]; meiotic cell cycle [GO:0051321] 0.95436 -1.5014 ATESQGKDSAK 0 0 0 0 9.27237 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z4N2 TRPM1_HUMAN Transient receptor potential cation channel subfamily M member 1 (Long transient receptor potential channel 1) (LTrpC1) (Melastatin-1) TRPM1 LTRPC1 MLSN MLSN1 Homo sapiens (Human) calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; cellular response to light stimulus [GO:0071482]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; monoatomic cation transmembrane transport [GO:0098655]; protein tetramerization [GO:0051262]; visual perception [GO:0007601] axon [GO:0030424]; endoplasmic reticulum membrane [GO:0005789]; plasma membrane [GO:0005886] calcium channel activity [GO:0005262] 0.93982 -1.3015 EEVEEETDPR 0 0 11.7148 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z4N8 P4HA3_HUMAN "Prolyl 4-hydroxylase subunit alpha-3 (4-PH alpha-3) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3)" P4HA3 UNQ711/PRO1374 Homo sapiens (Human) peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788] iron ion binding [GO:0005506]; L-ascorbic acid binding [GO:0031418]; procollagen-proline 4-dioxygenase activity [GO:0004656] 0.96332 -2.661 AGNVSCALSLSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.7057 0 9.62494 0 0 11.1367 0 Q7Z4S6 KI21A_HUMAN Kinesin-like protein KIF21A (Kinesin-like protein KIF2) (Renal carcinoma antigen NY-REN-62) KIF21A KIAA1708 KIF2 Homo sapiens (Human) microtubule-based movement [GO:0007018] axon [GO:0030424]; cytosol [GO:0005829]; dendrite [GO:0030425]; kinesin complex [GO:0005871]; microtubule [GO:0005874]; plasma membrane [GO:0005886] ankyrin repeat binding [GO:0071532]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777] 0.96867 -3.0126 AYEKAEKSK 0 0 0 0 9.84721 0 9.32551 0 0 0 0 14.0067 0 0 11.7128 8.34833 0 0 0 0 0 0 0 10.3614 0 0 9.44321 Q7Z4V0 ZN438_HUMAN Zinc finger protein 438 ZNF438 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; regulation of transcription by RNA polymerase II [GO:0006357] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]" 0.86986 0.057627 IKSDANIAGFSLPGPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.41316 0 0 Q7Z4V5 HDGR2_HUMAN Hepatoma-derived growth factor-related protein 2 (HDGF-related protein 2) (HRP-2) (Hepatoma-derived growth factor 2) (HDGF-2) HDGFL2 HDGF2 HDGFRP2 HRP2 UNQ785/PRO1604 Homo sapiens (Human) chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA repair-dependent chromatin remodeling [GO:0140861]; muscle cell differentiation [GO:0042692]; muscle organ development [GO:0007517]; positive regulation of cell growth [GO:0030307]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; skeletal muscle tissue regeneration [GO:0043403] cytoplasm [GO:0005737]; nucleus [GO:0005634] H3K27me3 modified histone binding [GO:0061628]; H3K9me3 modified histone binding [GO:0062072]; histone reader activity [GO:0140566]; methylated histone binding [GO:0035064] 0.97007 -4.3242 DLFPYDK 0 13.9498 0 0 0 0 0 0 0 0 0 0 0 0 11.7796 12.9609 0 0 0 0 9.27598 0 0 0 0 0 0 Q7Z4W1 DCXR_HUMAN L-xylulose reductase (XR) (EC 1.1.1.10) (Carbonyl reductase II) (Dicarbonyl/L-xylulose reductase) (Kidney dicarbonyl reductase) (kiDCR) (Short chain dehydrogenase/reductase family 20C member 1) (Sperm surface protein P34H) DCXR SDR20C1 Homo sapiens (Human) D-xylose metabolic process [GO:0042732]; glucose metabolic process [GO:0006006]; glucuronate catabolic process to xylulose 5-phosphate [GO:0019640]; NADP metabolic process [GO:0006739]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; xylulose metabolic process [GO:0005997] brush border [GO:0005903]; cytoplasmic microtubule [GO:0005881]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886] "carbonyl reductase (NADPH) activity [GO:0004090]; identical protein binding [GO:0042802]; L-xylulose reductase (NADP+) activity [GO:0050038]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]" 0.72119 0.36271 TQADLDSLVR 0 0 0 0 0 0 0 0 0 0 9.59595 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.96953 10.4875 Q7Z553 MDGA2_HUMAN MAM domain-containing glycosylphosphatidylinositol anchor protein 2 (MAM domain-containing protein 1) MDGA2 MAMDC1 UNQ8188/PRO23197 Homo sapiens (Human) nervous system development [GO:0007399]; spinal cord motor neuron differentiation [GO:0021522] extracellular region [GO:0005576]; plasma membrane [GO:0005886] 0.82599 0.21217 ITNIQRHQGGRYYCK 0 0 0 10.215 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z569 BRAP_HUMAN BRCA1-associated protein (EC 2.3.2.27) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (RING-type E3 ubiquitin transferase BRAP2) (Renal carcinoma antigen NY-REN-63) BRAP RNF52 Homo sapiens (Human) MAPK cascade [GO:0000165]; negative regulation of signal transduction [GO:0009968]; protein ubiquitination [GO:0016567]; Ras protein signal transduction [GO:0007265] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; ubiquitin ligase complex [GO:0000151] identical protein binding [GO:0042802]; nuclear localization sequence binding [GO:0008139]; nucleic acid binding [GO:0003676]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.96907 -4.8406 CDNLEHKLNDLLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5324 0 0 0 0 0 0 0 0 Q7Z570 Z804A_HUMAN Zinc finger protein 804A ZNF804A C2orf10 Homo sapiens (Human) positive regulation of dendritic spine maintenance [GO:1902952]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron projection development [GO:0010976]; regulation of neuron projection development [GO:0010975] cytoplasm [GO:0005737]; dendritic microtubule [GO:1901588]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; presynapse [GO:0098793] metal ion binding [GO:0046872] 0.9702 -3.2817 ALEDLKANFYCELCDKQYYK 12.3488 12.6587 12.3028 12.8627 13.017 12.9347 12.2289 0 12.5149 13.3254 12.8152 10.8191 0 0 11.899 0 0 0 9.87666 0 0 0 0 0 0 0 0 Q7Z572 SPT21_HUMAN Spermatogenesis-associated protein 21 SPATA21 Homo sapiens (Human) calcium ion binding [GO:0005509] 0.95187 -1.4396 LYQNREK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.5598 0 0 0 Q7Z589 EMSY_HUMAN BRCA2-interacting transcriptional repressor EMSY EMSY C11orf30 GL002 Homo sapiens (Human) chromatin organization [GO:0006325]; DNA repair [GO:0006281]; regulation of DNA-templated transcription [GO:0006355] nucleoplasm [GO:0005654] 0.89821 -0.59327 GIGSTVQPAAK 0 0 0 0 0 0 0 0 0 0 11.9894 9.97699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z591 AKNA_HUMAN Microtubule organization protein AKNA (AT-hook-containing transcription factor) AKNA KIAA1968 Homo sapiens (Human) delamination [GO:0060232]; epithelial to mesenchymal transition [GO:0001837]; neuroblast delamination [GO:0060234]; neuroblast division in subventricular zone [GO:0021849]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of inflammatory response [GO:0050727] centriole [GO:0005814]; centrosome [GO:0005813]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; microtubule [GO:0005874]; nucleoplasm [GO:0005654] DNA binding [GO:0003677] 0.88737 -0.34225 SLPEAMR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0653 0 8.31958 8.33918 0 0 0 Q7Z5B4 RIC3_HUMAN Protein RIC-3 (Resistant to inhibitor of cholinesterase 3) RIC3 UNQ720/PRO1385 Homo sapiens (Human) "positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of protein localization to cell surface [GO:2000010]; protein localization to cell surface [GO:0034394]; protein-containing complex assembly [GO:0065003]; synaptic transmission, cholinergic [GO:0007271]" endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; synapse [GO:0045202] acetylcholine receptor binding [GO:0033130]; protein folding chaperone [GO:0044183] 0.69023 0.38625 LSKGKTTAEDGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.56014 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z5D8 NANGN_HUMAN NANOG neighbor homeobox (Homeobox protein C14) NANOGNB Homo sapiens (Human) nucleus [GO:0005634] DNA binding [GO:0003677] 0.92704 -1.2195 ARWLTPVIPALWEAEAGRSR 0 0 8.30547 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.70364 9.8873 0 0 0 0 0 0 0 Q7Z5G4 GOGA7_HUMAN Golgin subfamily A member 7 (Golgi complex-associated protein of 16 kDa) GOLGA7 GCP16 HDCKB03P HSPC041 Homo sapiens (Human) Golgi to plasma membrane protein transport [GO:0043001]; Golgi to plasma membrane transport [GO:0006893]; peptidyl-L-cysteine S-palmitoylation [GO:0018230]; protein stabilization [GO:0050821]; protein targeting to membrane [GO:0006612] extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; palmitoyltransferase complex [GO:0002178]; tertiary granule lumen [GO:1904724] 0.78864 0.2501 YIQEQNEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.83637 0 0 9.69491 0 10.6755 0 10.9694 0 0 0 0 Q7Z5H3 RHG22_HUMAN Rho GTPase-activating protein 22 (Rho-type GTPase-activating protein 22) ARHGAP22 RHOGAP2 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; regulation of postsynapse organization [GO:0099175]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] cytosol [GO:0005829]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; nucleus [GO:0005634] GTPase activator activity [GO:0005096] 0.95814 -1.6882 AELCRQR 0 0 10.1152 0 0 9.25852 0 0 0 11.6321 0 0 0 0 0 12.007 0 0 0 0 0 0 0 0 0 0 0 Q7Z5H4 VN1R5_HUMAN Vomeronasal type-1 receptor 5 (G-protein coupled receptor GPCR26) (hGPCR26) (V1r-like receptor 5) VN1R5 V1RL5 Homo sapiens (Human) response to pheromone [GO:0019236] plasma membrane [GO:0005886] pheromone receptor activity [GO:0016503] 0.89038 -0.49814 LHGDYFIQTIR 0 0 0 0 11.7635 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z5J4 RAI1_HUMAN Retinoic acid-induced protein 1 RAI1 KIAA1820 Homo sapiens (Human) circadian regulation of gene expression [GO:0032922]; negative regulation of multicellular organism growth [GO:0040015]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501] cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] metal ion binding [GO:0046872] 0.95319 -1.4879 AKNTTSSPCK 9.20136 12.6339 12.7103 11.0977 12.0526 10.4148 0 9.78807 0 13.0437 8.63608 11.4073 11.6657 11.9732 0 12.5558 12.1401 12.3566 0 0 9.48718 0 0 0 0 0 0 Q7Z5K2 WAPL_HUMAN Wings apart-like protein homolog (Friend of EBNA2 protein) (WAPL cohesin release factor) WAPL FOE KIAA0261 WAPAL Homo sapiens (Human) cell division [GO:0051301]; mitotic sister chromatid segregation [GO:0000070]; negative regulation of chromatin binding [GO:0035562]; negative regulation of DNA replication [GO:0008156]; negative regulation of sister chromatid cohesion [GO:0045875]; protein localization to chromatin [GO:0071168]; regulation of cohesin loading [GO:0071922] "chromatin [GO:0000785]; chromosome [GO:0005694]; chromosome, centromeric region [GO:0000775]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; intracellular membrane-bounded organelle [GO:0043231]; mitotic spindle [GO:0072686]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]" ATP-dependent protein-DNA unloader activity [GO:0140083] 0.91981 -0.90823 AGDWFKEELR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.97327 0 0 0 9.73679 0 0 0 Q7Z5L2 R3HCL_HUMAN Coiled-coil domain-containing protein R3HCC1L (Growth inhibition and differentiation-related protein 88) (Putative mitochondrial space protein 32.1) (R3H and coiled-coil domain-containing protein 1-like) R3HCC1L C10orf28 GIDRP88 Homo sapiens (Human) 0.9633 -2.1401 LNINPDRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.0769 0 0 0 0 0 0 0 10.6964 0 0 Q7Z5L7 PODN_HUMAN Podocan PODN SLRR5A UNQ293/PRO332 Homo sapiens (Human) negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285] collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular space [GO:0005615] collagen binding [GO:0005518] 0.61281 0.42603 VPSGLPR 9.93965 10.0735 9.98925 0 0 0 10.0786 9.99393 9.85969 10.3872 10.5603 10.2629 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z5L9 I2BP2_HUMAN Interferon regulatory factor 2-binding protein 2 (IRF-2-binding protein 2) (IRF-2BP2) IRF2BP2 Homo sapiens (Human) immature B cell differentiation [GO:0002327]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] metal ion binding [GO:0046872]; transcription corepressor activity [GO:0003714] 0.86428 0.075908 AAAVAVAAASR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1789 0 0 0 0 0 0 0 0 0 0 0 Q7Z5M5 TMC3_HUMAN Transmembrane channel-like protein 3 TMC3 Homo sapiens (Human) plasma membrane [GO:0005886] mechanosensitive monoatomic ion channel activity [GO:0008381] 0.96198 -2.5553 MQIQNARSEDKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.31685 0 0 0 0 0 0 10.4801 0 10.0967 10.3222 0 Q7Z5N4 SDK1_HUMAN Protein sidekick-1 SDK1 Homo sapiens (Human) behavioral response to cocaine [GO:0048148]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; regulation of dendritic spine development [GO:0060998]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] plasma membrane [GO:0005886]; synapse [GO:0045202] identical protein binding [GO:0042802] 0.96784 -3.7319 DLTKGVTYFFR 11.3021 11.3639 10.9973 0 9.71764 9.28958 10.8683 11.0955 11.0385 10.2367 10.1162 10.1808 0 0 0 0 0 9.4761 0 0 0 10.761 0 0 0 0 0 Q7Z5P9 MUC19_HUMAN Mucin-19 (MUC-19) MUC19 Homo sapiens (Human) extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886] 0.96387 -2.4149 AWAVRKCEILR 0 0 11.2641 8.94518 9.04985 9.21822 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.07957 0 9.6861 0 0 0 Q7Z5Q5 DPOLN_HUMAN DNA polymerase nu (EC 2.7.7.7) POLN Homo sapiens (Human) DNA-templated DNA replication [GO:0006261]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; interstrand cross-link repair [GO:0036297]; translesion synthesis [GO:0019985] nucleoplasm [GO:0005654]; nucleus [GO:0005634] cyclin binding [GO:0030332]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887] 0.9673 -2.3512 DDVFSTLTSQWKDVPVEQVTHADR 0 0 0 0 0 0 0 0 0 0 9.52138 0 0 0 0 12.2996 0 0 0 0 0 0 8.91262 10.8032 0 0 0 Q7Z5W3 BN3D2_HUMAN RNA 5'-monophosphate methyltransferase (EC 2.1.1.-) (BCDIN3 domain-containing protein) BCDIN3D Homo sapiens (Human) miRNA metabolic process [GO:0010586]; negative regulation of pre-miRNA processing [GO:2000632]; pre-miRNA processing [GO:0031054]; RNA methylation [GO:0001510]; tRNA methylation [GO:0030488] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654] O-methyltransferase activity [GO:0008171]; pre-miRNA binding [GO:0070883]; RNA methyltransferase activity [GO:0008173]; small RNA 2'-O-methyltransferase activity [GO:0090486]; tRNA methyltransferase activity [GO:0008175] 0.82568 0.21213 ETAAEEESR 0 0 0 0 0 9.74403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z5Y6 BMP8A_HUMAN Bone morphogenetic protein 8A (BMP-8A) BMP8A Homo sapiens (Human) cartilage development [GO:0051216]; cell differentiation [GO:0030154]; diet induced thermogenesis [GO:0002024]; energy homeostasis [GO:0097009]; negative regulation of insulin secretion [GO:0046676]; ossification [GO:0001503]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; SMAD protein signal transduction [GO:0060395] extracellular space [GO:0005615] cytokine activity [GO:0005125]; growth factor activity [GO:0008083] 0.91424 -0.78136 ALGHQEPHWKEFR 0 0 0 0 0 8.95571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z5Y7 KCD20_HUMAN BTB/POZ domain-containing protein KCTD20 (Potassium channel tetramerization domain containing 20) KCTD20 C6orf69 Homo sapiens (Human) positive regulation of phosphorylation [GO:0042327] cytoplasm [GO:0005737] 0.85058 0.16019 TVLDYYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0497 0 0 0 0 0 Q7Z601 GP142_HUMAN Probable G-protein coupled receptor 142 (G-protein coupled receptor PGR2) GPR142 PGR2 Homo sapiens (Human) cell junction [GO:0030054]; cytosol [GO:0005829]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930] 0.88713 -0.34761 ATAGQPR 0 0 0 0 0 0 8.44236 0 0 0 0 0 0 9.59156 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z602 GP141_HUMAN Probable G-protein coupled receptor 141 (G-protein coupled receptor PGR13) GPR141 PGR13 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; oxysterol binding [GO:0008142] 0.85025 0.15869 ELAYTYVK 0 0 0 0 0 0 0 0 0 0 12.2432 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z614 SNX20_HUMAN Sorting nexin-20 (Selectin ligand-interactor cytoplasmic 1) (SLIC-1) SNX20 SLIC1 Homo sapiens (Human) protein transport [GO:0015031] early endosome membrane [GO:0031901]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] "phosphatidylinositol phosphate binding [GO:1901981]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]" 0.95131 -1.3998 ELTVREYLH 0 0 0 0 0 0 0 0 0 0 0 12.8871 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z692 CEA19_HUMAN Carcinoembryonic antigen-related cell adhesion molecule 19 (Carcinoembryonic antigen-like 1) CEACAM19 CEAL1 UNQ2973/PRO7436 Homo sapiens (Human) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157] cell surface [GO:0009986]; membrane [GO:0016020] 0.76468 0.27941 MEIPMGTQGCFSK 8.86261 0 0 0 0 0 0 0 0 13.6495 13.3191 13.2525 0 0 8.76858 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z695 ADCK2_HUMAN Uncharacterized aarF domain-containing protein kinase 2 (EC 2.7.11.-) ADCK2 AARF Homo sapiens (Human) phosphorylation [GO:0016310] membrane [GO:0016020] ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674] 0.59057 0.45282 ADLVGSNAGVSR 0 0 0 0 0 0 0 0 0 0 0 7.83143 0 0 0 0 0 0 0 0 0 0 0 0 10.1762 0 0 Q7Z6A9 BTLA_HUMAN B- and T-lymphocyte attenuator (B- and T-lymphocyte-associated protein) (CD antigen CD272) BTLA Homo sapiens (Human) adaptive immune response [GO:0002250]; immune response-regulating cell surface receptor signaling pathway [GO:0002768] plasma membrane [GO:0005886] signaling receptor activity [GO:0038023] 0.95731 -1.6523 LEDRQTSWK 0 0 0 0 0 0 0 0 0 9.75303 0 0 0 0 0 0 0 0 10.1253 0 0 0 0 0 0 0 0 Q7Z6B7 SRGP1_HUMAN SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho GTPase-activating protein 13) SRGAP1 ARHGAP13 KIAA1304 Homo sapiens (Human) negative regulation of cell migration [GO:0030336]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829] GTPase activator activity [GO:0005096] 0.86708 0.072609 CLEQQTEMR 0 0 0 0 10.703 10.295 0 0 0 12.0392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z6E9 RBBP6_HUMAN E3 ubiquitin-protein ligase RBBP6 (EC 2.3.2.27) (Proliferation potential-related protein) (Protein P2P-R) (RING-type E3 ubiquitin transferase RBBP6) (Retinoblastoma-binding Q protein 1) (RBQ-1) (Retinoblastoma-binding protein 6) (p53-associated cellular protein of testis) RBBP6 P2PR PACT RBQ1 My038 Homo sapiens (Human) DNA damage response [GO:0006974]; DNA replication [GO:0006260]; embryonic organ development [GO:0048568]; in utero embryonic development [GO:0001701]; mRNA processing [GO:0006397]; multicellular organism growth [GO:0035264]; protein ubiquitination [GO:0016567]; regulation of DNA replication [GO:0006275]; somite development [GO:0061053]; ubiquitin-dependent protein catabolic process [GO:0006511] chromosome [GO:0005694]; cytosol [GO:0005829]; microtubule organizing center [GO:0005815]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.96853 -10.215 DLKDKIVEK 9.20789 9.05279 0 0 0 0 0 9.67876 0 12.8773 10.5061 8.77873 9.9074 9.81134 0 0 0 9.99478 0 0 0 8.63125 0 0 11.5474 0 0 Q7Z6G3 NECA2_HUMAN N-terminal EF-hand calcium-binding protein 2 (EF-hand calcium-binding protein 2) (Neuronal calcium-binding protein 2) (Synaptotagmin-interacting protein 2) (Stip-2) NECAB2 EFCBP2 Homo sapiens (Human) negative regulation of G protein-coupled receptor internalization [GO:1904021]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glutamate receptor signaling pathway [GO:1900451]; positive regulation of protein localization to membrane [GO:1905477]; regulation of amyloid precursor protein biosynthetic process [GO:0042984] axon [GO:0030424]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; plasma membrane [GO:0005886] A2A adenosine receptor binding [GO:0031687]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; type 5 metabotropic glutamate receptor binding [GO:0031802] 0.95245 -1.4616 ALWFDLQQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1387 0 0 0 0 0 0 0 0 Q7Z6G8 ANS1B_HUMAN Ankyrin repeat and sterile alpha motif domain-containing protein 1B (Amyloid-beta protein intracellular domain-associated protein 1) (AIDA-1) (E2A-PBX1-associated protein) (EB-1) ANKS1B Homo sapiens (Human) ephrin receptor signaling pathway [GO:0048013] Cajal body [GO:0015030]; centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] ephrin receptor binding [GO:0046875] 0.95462 -1.5016 ANCQKSTEQMK 0 0 0 0 0 0 0 9.34842 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z6I6 RHG30_HUMAN Rho GTPase-activating protein 30 (Rho-type GTPase-activating protein 30) ARHGAP30 Homo sapiens (Human) regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264] cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231] GTPase activator activity [GO:0005096] 0.91475 -0.77827 ERESGDGEAEGDQR 0 0 0 0 0 0 0 0 0 0 11.5877 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z6J0 SH3R1_HUMAN E3 ubiquitin-protein ligase SH3RF1 (EC 2.3.2.27) (Plenty of SH3s) (Protein POSH) (RING finger protein 142) (RING-type E3 ubiquitin transferase SH3RF1) (SH3 domain-containing RING finger protein 1) (SH3 multiple domains protein 2) SH3RF1 KIAA1494 POSH POSH1 RNF142 SH3MD2 Homo sapiens (Human) "negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; neuron migration [GO:0001764]; positive regulation of JNK cascade [GO:0046330]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043370]; regulation of CD8-positive, alpha-beta T cell proliferation [GO:2000564]" cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; lamellipodium [GO:0030027]; perinuclear region of cytoplasm [GO:0048471] MAP-kinase scaffold activity [GO:0005078]; metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630] 0.87367 0.031991 VLPCQHTFCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.88634 0 0 0 0 0 0 Q7Z6J2 GRASP_HUMAN Protein TAMALIN (General receptor for phosphoinositides 1-associated scaffold protein) (GRP1-associated scaffold protein) TAMALIN GRASP Homo sapiens (Human) "protein localization [GO:0008104]; regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0099152]; signal transduction [GO:0007165]" glutamatergic synapse [GO:0098978]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; Schaffer collateral - CA1 synapse [GO:0098685] identical protein binding [GO:0042802]; PDZ domain binding [GO:0030165]; small GTPase binding [GO:0031267] 0.80316 0.24048 VEMVTFVCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.33646 0 0 0 0 0 7.96399 0 0 Q7Z6J4 FGD2_HUMAN "FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4)" FGD2 ZFYVE4 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cytoskeleton organization [GO:0007010]; filopodium assembly [GO:0046847]; positive regulation of JUN kinase activity [GO:0043507]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; Golgi apparatus [GO:0005794]; lamellipodium [GO:0030027]; nucleus [GO:0005634]; ruffle [GO:0001726]; ruffle membrane [GO:0032587] guanyl-nucleotide exchange factor activity [GO:0005085]; metal ion binding [GO:0046872]; phosphatidylinositol phosphate binding [GO:1901981]; small GTPase binding [GO:0031267] 0.72737 0.34181 CQEPFNALTR 0 0 0 0 0 0 0 0 0 9.3347 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z6J6 FRMD5_HUMAN FERM domain-containing protein 5 FRMD5 Homo sapiens (Human) actomyosin structure organization [GO:0031032]; negative regulation of cell motility [GO:2000146]; positive regulation of cell adhesion [GO:0045785]; regulation of cell migration [GO:0030334] adherens junction [GO:0005912]; cytoskeleton [GO:0005856]; membrane [GO:0016020] cytoskeletal protein binding [GO:0008092]; integrin binding [GO:0005178]; protein kinase binding [GO:0019901] 0.96932 -4.1128 AGMVPSR 0 0 0 0 0 0 0 0 0 0 0 13.6657 0 0 0 0 0 0 0 0 0 0 9.43538 0 0 0 0 Q7Z6J8 UBE3D_HUMAN E3 ubiquitin-protein ligase E3D (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase E3D) (UbcH10-binding protein with a HECT-like domain) (Ubiquitin-conjugating enzyme E2C-binding protein) UBE3D C6orf157 H10BH UBE2CBP Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209] cytosol [GO:0005829]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151] cyclin binding [GO:0030332]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-like protein conjugating enzyme binding [GO:0044390] 0.83401 0.19982 FTIQGQDDK 9.35511 0 0 0 0 8.71905 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z6J9 SEN54_HUMAN tRNA-splicing endonuclease subunit Sen54 (SEN54 homolog) (HsSEN54) (tRNA-intron endonuclease Sen54) TSEN54 SEN54 Homo sapiens (Human) "mRNA processing [GO:0006397]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]; tRNA-type intron splice site recognition and cleavage [GO:0000379]" nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; tRNA-intron endonuclease complex [GO:0000214] 0.83472 0.19191 ALDNSLQPK 0 0 0 0 0 0 9.67258 9.85457 9.65349 8.71394 8.8653 8.70522 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z6K5 ARPIN_HUMAN Arpin (Arp2/3 inhibition protein) ARPIN C15orf38 Homo sapiens (Human) directional locomotion [GO:0033058]; negative regulation of actin nucleation [GO:0051126]; negative regulation of cell migration [GO:0030336]; negative regulation of lamellipodium morphogenesis [GO:2000393] lamellipodium [GO:0030027] 0.84046 0.18413 EQGDGAEDEEWDD 9.22624 0 0 0 0 0 0 9.62013 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z6L0 PRRT2_HUMAN Proline-rich transmembrane protein 2 (Dispanin subfamily B member 3) (DSPB3) PRRT2 Homo sapiens (Human) negative regulation of short-term synaptic potentiation [GO:1905513]; negative regulation of SNARE complex assembly [GO:0035544]; neuromuscular process controlling posture [GO:0050884]; regulation of calcium-dependent activation of synaptic vesicle fusion [GO:0150037]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629] axon terminus [GO:0043679]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; presynapse [GO:0098793]; presynaptic membrane [GO:0042734]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; vesicle [GO:0031982] syntaxin-1 binding [GO:0017075] 0.65399 0.3955 GVEESPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.32085 0 0 0 10.4029 Q7Z6L1 TCPR1_HUMAN Tectonin beta-propeller repeat-containing protein 1 TECPR1 KIAA1358 Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; macroautophagy [GO:0016236]; regulation of autophagosome maturation [GO:1901096] autophagosome membrane [GO:0000421]; cytoplasmic vesicle [GO:0031410]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991] phosphatidylinositol-3-phosphate binding [GO:0032266] 0.96425 -2.3971 EGINRSNPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.54622 0 0 0 0 0 0 Q7Z6M1 RABEK_HUMAN Rab9 effector protein with kelch motifs (40 kDa Rab9 effector protein) (p40) RABEPK RAB9P40 Homo sapiens (Human) receptor-mediated endocytosis [GO:0006898]; vesicle docking involved in exocytosis [GO:0006904] cytosol [GO:0005829]; endosome [GO:0005768]; endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; trans-Golgi network membrane [GO:0032588]; transport vesicle [GO:0030133] 0.56142 0.50712 HQWDLDTCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3415 0 0 0 0 0 0 0 0 Q7Z6M4 MTEF4_HUMAN "Transcription termination factor 4, mitochondrial (Mitochondrial transcription termination factor 4) (mTERF domain-containing protein 2) [Cleaved into: mTERF domain-containing protein 2 processed]" MTERF4 MTERFD2 HSPC096 Homo sapiens (Human) camera-type eye development [GO:0043010]; heart development [GO:0007507]; mitochondrial ribosome assembly [GO:0061668]; mitochondrial transcription [GO:0006390]; protein targeting to mitochondrion [GO:0006626]; regulation of DNA-templated transcription [GO:0006355]; rRNA processing [GO:0006364] cytosol [GO:0005829]; mitochondrial large ribosomal subunit [GO:0005762]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] double-stranded DNA binding [GO:0003690]; rRNA binding [GO:0019843] 0.95423 -1.5154 FQYAYFRMGIK 0 0 0 0 0 0 0 0 9.657 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z6P3 RAB44_HUMAN Ras-related protein Rab-44 RAB44 Homo sapiens (Human) histamine secretion by mast cell [GO:0002553]; histamine secretion mediated by IgE immunoglobulin [GO:0097279]; vesicle-mediated transport [GO:0016192] azurophil granule membrane [GO:0035577]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579] calcium ion binding [GO:0005509]; GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.92046 -0.92311 EDLAVAKFSFLGSKEESEMIFDWVDVER 0 0 12.4976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.44232 0 0 0 0 0 Q7Z6R9 AP2D_HUMAN Transcription factor AP-2-delta (AP2-delta) (Activating enhancer-binding protein 2-delta) (Transcription factor AP-2-beta-like 1) TFAP2D TFAP2BL1 Homo sapiens (Human) anatomical structure development [GO:0048856]; inferior colliculus development [GO:0061379]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell population proliferation [GO:0042127]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] chromatin [GO:0000785]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.94093 -1.3311 AVGEHLARQHMEQK 0 0 0 0 0 0 0 0 0 0 10.0518 9.81671 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z6W7 DNJB7_HUMAN DnaJ homolog subfamily B member 7 DNAJB7 HSC3 Homo sapiens (Human) chaperone-mediated protein folding [GO:0061077] cytoplasm [GO:0005737]; nucleus [GO:0005634] Hsp70 protein binding [GO:0030544]; protein folding chaperone [GO:0044183]; protein-folding chaperone binding [GO:0051087]; unfolded protein binding [GO:0051082] 0.77187 0.27022 IIESDQER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4332 0 0 0 0 0 0 9.30659 Q7Z6Z7 HUWE1_HUMAN "E3 ubiquitin-protein ligase HUWE1 (EC 2.3.2.26) (ARF-binding protein 1) (ARF-BP1) (HECT, UBA and WWE domain-containing protein 1) (HECT-type E3 ubiquitin transferase HUWE1) (Homologous to E6AP carboxyl terminus homologous protein 9) (HectH9) (Large structure of UREB1) (LASU1) (Mcl-1 ubiquitin ligase E3) (Mule) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1)" HUWE1 KIAA0312 KIAA1578 UREB1 HSPC272 Homo sapiens (Human) base-excision repair [GO:0006284]; cell differentiation [GO:0030154]; circadian regulation of gene expression [GO:0032922]; negative regulation of mitochondrial fusion [GO:0010637]; positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774] DNA binding [GO:0003677]; histone ubiquitin ligase activity [GO:0140852]; RNA binding [GO:0003723]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.96893 -4.5275 AGTTQGGK 0 0 0 0 0 0 8.27598 0 0 0 0 0 0 0 9.71077 0 0 0 0 9.16531 0 0 9.26315 0 0 0 0 Q7Z713 ANR37_HUMAN Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp) ANKRD37 LPR2BP Homo sapiens (Human) cytoplasm [GO:0005737]; cytosol [GO:0005829]; male germ cell nucleus [GO:0001673]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] 0.8863 -0.36266 SLGSVENTSGKR 0 0 0 0 0 0 0 0 0 0 0 10.3697 0 0 0 0 0 0 0 0 0 0 0 9.95646 11.0104 0 0 Q7Z736 PKHH3_HUMAN Pleckstrin homology domain-containing family H member 3 (PH domain-containing family H member 3) PLEKHH3 Homo sapiens (Human) signal transduction [GO:0007165] cytoskeleton [GO:0005856]; extracellular space [GO:0005615] 0.94704 -1.358 LQSLQRDFSPRVPLPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0007 0 Q7Z745 MRO2B_HUMAN Maestro heat-like repeat-containing protein family member 2B (HEAT repeat-containing protein 7B2) (Sperm PKA-interacting factor) (SPIF) MROH2B HEATR7B2 Homo sapiens (Human) cell differentiation [GO:0030154]; protein kinase A signaling [GO:0010737]; spermatogenesis [GO:0007283] acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; sperm flagellum [GO:0036126]; sperm midpiece [GO:0097225] 0.89826 -0.60636 CLQAQAMR 0 9.3552 0 0 0 0 0 0 0 0 9.62503 0 10.0593 0 0 0 0 0 0 0 9.49229 0 0 0 0 0 0 Q7Z794 K2C1B_HUMAN "Keratin, type II cytoskeletal 1b (Cytokeratin-1B) (CK-1B) (Keratin-77) (K77) (Type-II keratin Kb39)" KRT77 KRT1B Homo sapiens (Human) keratinization [GO:0031424] cornified envelope [GO:0001533]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; keratin filament [GO:0045095] structural constituent of skin epidermis [GO:0030280] 0.88843 -0.43168 EQIMVLNNK 0 8.69439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1895 0 9.8463 0 0 9.11938 0 Q7Z7A1 CNTRL_HUMAN Centriolin (Centrosomal protein 1) (Centrosomal protein of 110 kDa) (Cep110) CNTRL CEP1 CEP110 Homo sapiens (Human) aorta development [GO:0035904]; cell cycle [GO:0007049]; cell division [GO:0051301]; coronary vasculature development [GO:0060976]; kidney development [GO:0001822]; ventricular septum development [GO:0003281] centriolar satellite [GO:0034451]; centriolar subdistal appendage [GO:0120103]; centrosome [GO:0005813]; cytosol [GO:0005829]; Flemming body [GO:0090543]; meiotic spindle pole [GO:0090619]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; mitotic spindle pole [GO:0097431]; perinuclear region of cytoplasm [GO:0048471] 0.96846 -10.244 ADQQLRSLQADAKDLEQHK 10.9807 10.978 10.3563 9.56693 9.77671 9.4188 11.6836 9.99605 10.7551 12.5273 0 0 0 11.0549 11.4502 9.60992 9.82539 0 0 10.0612 0 0 0 9.54361 9.10525 0 8.98188 Q7Z7A3 CTU1_HUMAN Cytoplasmic tRNA 2-thiolation protein 1 (EC 2.7.7.-) (ATP-binding domain-containing protein 3) (Cancer-associated gene protein) (Cytoplasmic tRNA adenylyltransferase 1) CTU1 ATPBD3 NCS6 Homo sapiens (Human) protein urmylation [GO:0032447]; tRNA thio-modification [GO:0034227]; tRNA wobble position uridine thiolation [GO:0002143]; tRNA wobble uridine modification [GO:0002098] cytosol [GO:0005829]; cytosolic tRNA wobble base thiouridylase complex [GO:0002144] nucleotidyltransferase activity [GO:0016779]; tRNA binding [GO:0000049] 0.64951 0.39598 STAGSGR 9.32233 8.78584 8.88023 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z7A4 PXK_HUMAN "PX domain-containing protein kinase-like protein (Modulator of Na,K-ATPase) (MONaKA)" PXK Homo sapiens (Human) early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; inflammatory response [GO:0006954]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of ATP-dependent activity [GO:0032780]; negative regulation of monoatomic ion transport [GO:0043271]; protein targeting to lysosome [GO:0006622] centriolar satellite [GO:0034451]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; extrinsic component of endosome membrane [GO:0031313]; late endosome [GO:0005770]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] actin binding [GO:0003779]; phosphatidylinositol binding [GO:0035091] 0.9548 -1.62 AKTCDHSAPK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.04625 0 10.9918 0 8.24759 0 0 0 0 0 0 0 10.7152 0 Q7Z7B0 FLIP1_HUMAN Filamin-A-interacting protein 1 (FILIP) FILIP1 KIAA1275 Homo sapiens (Human) actin cytoskeleton [GO:0015629]; cytosol [GO:0005829]; nucleolus [GO:0005730]; plasma membrane [GO:0005886] 0.96509 -2.7053 EDDVMASGTVKR 9.51412 9.37955 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.99534 9.24263 0 0 0 0 9.9186 0 0 Q7Z7B1 PIGW_HUMAN Phosphatidylinositol-glycan biosynthesis class W protein (PIG-W) (EC 2.3.-.-) PIGW Homo sapiens (Human) GPI anchor biosynthetic process [GO:0006506]; GPI anchor metabolic process [GO:0006505]; preassembly of GPI anchor in ER membrane [GO:0016254]; protein localization to plasma membrane [GO:0072659] endoplasmic reticulum membrane [GO:0005789] glucosaminyl-phosphatidylinositol O-acyltransferase activity [GO:0032216]; O-acyltransferase activity [GO:0008374] 0.87756 -0.0056403 GALVPCSWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.78705 0 0 0 0 0 Q7Z7B8 DB128_HUMAN "Beta-defensin 128 (Beta-defensin 28) (DEFB-28) (Defensin, beta 128)" DEFB128 DEFB28 Homo sapiens (Human) defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; killing of cells of another organism [GO:0031640] extracellular region [GO:0005576] 0.95276 -1.4811 VGERYEIGCLSGK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7084 10.582 0 10.3981 0 0 0 0 0 0 0 0 0 0 Q7Z7C8 TAF8_HUMAN Transcription initiation factor TFIID subunit 8 (Protein taube nuss) (TBP-associated factor 43 kDa) (TBP-associated factor 8) (Transcription initiation factor TFIID 43 kDa subunit) (TAFII-43) (TAFII43) (hTAFII43) TAF8 TAFII43 TBN Homo sapiens (Human) cell differentiation [GO:0030154]; DNA-templated transcription open complex formation [GO:0001112]; inner cell mass cell proliferation [GO:0001833]; maintenance of protein location in nucleus [GO:0051457]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; protein phosphorylation [GO:0006468]; regulation of fat cell differentiation [GO:0045598]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription initiation at RNA polymerase II promoter [GO:0006367] nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; transcription factor TFIID complex [GO:0005669] protein heterodimerization activity [GO:0046982]; RNA polymerase II general transcription initiation factor activity [GO:0016251] 0.962 -2.4519 RSQRMVITAPPVTNQPVTPK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.91132 0 0 0 0 0 0 0 0 0 0 0 11.2339 0 Q7Z7D3 VTCN1_HUMAN V-set domain-containing T-cell activation inhibitor 1 (B7 homolog 4) (B7-H4) (B7h.5) (Immune costimulatory protein B7-H4) (Protein B7S1) (T-cell costimulatory molecule B7x) VTCN1 B7H4 UNQ659/PRO1291 Homo sapiens (Human) adaptive immune response [GO:0002250]; negative regulation of apoptotic process [GO:0043066]; negative regulation of T cell activation [GO:0050868]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of T cell proliferation [GO:0042102]; regulation of cytokine production [GO:0001817]; response to protozoan [GO:0001562]; T cell receptor signaling pathway [GO:0050852] external side of plasma membrane [GO:0009897] signaling receptor binding [GO:0005102] 0.96991 -3.2599 EGVLGLVHEFKEGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.99718 0 0 8.94298 0 Q7Z7E8 UB2Q1_HUMAN Ubiquitin-conjugating enzyme E2 Q1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme Q1) (Protein NICE-5) (Ubiquitin carrier protein Q1) (Ubiquitin-protein ligase Q1) UBE2Q1 NICE5 UBE2Q PRO3094 Homo sapiens (Human) embryo implantation [GO:0007566]; fertilization [GO:0009566]; mating behavior [GO:0007617]; prolactin secretion [GO:0070459]; protein polyubiquitination [GO:0000209]; reproductive system development [GO:0061458]; suckling behavior [GO:0001967] cytosol [GO:0005829]; filopodium [GO:0030175]; nucleus [GO:0005634] ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631] 0.85032 0.11753 QDYLNGAVSGSVQATDR 0 0 0 0 0 0 9.71569 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z7F7 RM55_HUMAN "Large ribosomal subunit protein mL55 (39S ribosomal protein L55, mitochondrial) (L55mt) (MRP-L55) (Mitochondrial large ribosomal subunit protein bL31m)" MRPL55 UNQ5835/PRO19675 Homo sapiens (Human) mitochondrial translation [GO:0032543]; translation [GO:0006412] mitochondrial inner membrane [GO:0005743]; mitochondrial large ribosomal subunit [GO:0005762]; mitochondrion [GO:0005739]; synapse [GO:0045202] structural constituent of ribosome [GO:0003735] 0.96106 -2.5603 ATGPALR 0 0 0 0 0 0 0 0 0 9.26271 8.93661 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z7G1 CLNK_HUMAN Cytokine-dependent hematopoietic cell linker (Mast cell immunoreceptor signal transducer) CLNK MIST Homo sapiens (Human) intracellular signal transduction [GO:0035556]; mast cell degranulation [GO:0043303]; negative regulation of natural killer cell activation [GO:0032815]; positive regulation of natural killer cell cytokine production [GO:0002729]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] cytoplasm [GO:0005737]; mast cell granule [GO:0042629]; protein-containing complex [GO:0032991] protein-containing complex binding [GO:0044877] 0.94128 -1.3163 DVRSQNIKGDASVR 0 0 0 9.04117 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z7G8 VP13B_HUMAN Intermembrane lipid transfer protein VPS13B (Cohen syndrome protein 1) (Vacuolar protein sorting-associated protein 13B) VPS13B CHS1 COH1 KIAA0532 Homo sapiens (Human) acrosome assembly [GO:0001675]; adipose tissue development [GO:0060612]; central nervous system development [GO:0007417]; Golgi organization [GO:0007030]; Golgi reassembly [GO:0090168]; lipid transport [GO:0006869]; maintenance of lens transparency [GO:0036438]; nervous system development [GO:0007399]; neuron projection development [GO:0031175]; slow endocytic recycling [GO:0032458]; vesicle-mediated transport [GO:0016192] acrosomal membrane [GO:0002080]; cis-Golgi network membrane [GO:0033106]; early endosome membrane [GO:0031901]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; Golgi membrane [GO:0000139]; lysosomal membrane [GO:0005765]; recycling endosome membrane [GO:0055038]; trans-Golgi network membrane [GO:0032588] phosphatidylinositol-3-phosphate binding [GO:0032266] 0.96954 -3.9659 DFEENMNR 0 0 0 0 0 0 0 0 0 0 0 9.64969 9.64369 0 0 0 0 0 11.4744 0 9.5878 0 0 0 0 0 0 Q7Z7H3 CATIP_HUMAN Ciliogenesis-associated TTC17-interacting protein CATIP C2orf62 Homo sapiens (Human) actin filament polymerization [GO:0030041]; cilium organization [GO:0044782] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886] 0.56678 0.50004 LGHASYLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.65319 0 0 0 0 0 0 0 0 0 9.24167 0 0 Q7Z7H5 TMED4_HUMAN Transmembrane emp24 domain-containing protein 4 (Endoplasmic reticulum stress-response protein 25) (ERS25) (GMP25iso) (Putative NF-kappa-B-activating protein 156) (p24 family protein alpha-3) (p24alpha3) TMED4 ERS25 Homo sapiens (Human) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123] COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794] 0.76535 0.28424 QLLDQVEQIQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.541 10.6844 Q7Z7K2 ZN467_HUMAN Zinc finger protein 467 ZNF467 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96197 -2.6236 DQLTLRLHQR 9.50861 0 0 9.80972 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q7Z7L1 SLN11_HUMAN Schlafen family member 11 (EC 3.6.-.-) SLFN11 Homo sapiens (Human) chromatin remodeling [GO:0006338]; defense response to virus [GO:0051607]; DNA damage response [GO:0006974]; immune system process [GO:0002376]; negative regulation of DNA replication [GO:0008156]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; replication fork arrest [GO:0043111] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of DNA damage [GO:0090734] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; helicase activity [GO:0004386]; tRNA binding [GO:0000049] 0.77217 0.27489 IEQAIYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.74819 10.1109 Q7Z7L8 CK096_HUMAN Uncharacterized protein C11orf96 (Protein Ag2 homolog) C11orf96 AG2 Homo sapiens (Human) 0.906 -0.72794 GAGEGDLRPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0576 0 0 0 0 0 0 0 0 Q7Z7M0 MEGF8_HUMAN Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4) MEGF8 C19orf49 EGFL4 KIAA0817 Homo sapiens (Human) BMP signaling pathway [GO:0030509]; cell migration involved in gastrulation [GO:0042074]; coronary vasculature development [GO:0060976]; craniofacial suture morphogenesis [GO:0097094]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of heart left/right asymmetry [GO:0061371]; embryonic heart tube left/right pattern formation [GO:0060971]; embryonic heart tube morphogenesis [GO:0003143]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; epiboly involved in gastrulation with mouth forming second [GO:0055113]; fasciculation of sensory neuron axon [GO:0097155]; left/right pattern formation [GO:0060972]; limb morphogenesis [GO:0035108]; negative regulation of smoothened signaling pathway [GO:0045879]; positive regulation of axon extension involved in axon guidance [GO:0048842]; regulation of gene expression [GO:0010468] extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634] calcium ion binding [GO:0005509] 0.92581 -1.2119 ETRRLQRPGSAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1941 0 0 0 0 0 Q7Z7M9 GALT5_HUMAN Polypeptide N-acetylgalactosaminyltransferase 5 (EC 2.4.1.41) (Polypeptide GalNAc transferase 5) (GalNAc-T5) (pp-GaNTase 5) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5) GALNT5 Homo sapiens (Human) glycosaminoglycan biosynthetic process [GO:0006024]; O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139] carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; polypeptide N-acetylgalactosaminyltransferase activity [GO:0004653] 0.9695 -4.0533 CISIENTTVILEDCDGSKELQQFNYTWLR 0 0 0 0 0 0 0 0 12.0565 0 10.2439 12.835 10.1687 0 0 10.0573 0 0 0 10.8686 10.6162 9.86885 0 0 10.088 8.94178 0 Q86SF2 GALT7_HUMAN N-acetylgalactosaminyltransferase 7 (EC 2.4.1.41) (Polypeptide GalNAc transferase 7) (GalNAc-T7) (pp-GaNTase 7) (Protein-UDP acetylgalactosaminyltransferase 7) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7) GALNT7 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020] carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; polypeptide N-acetylgalactosaminyltransferase activity [GO:0004653] 0.7541 0.30841 LLFVPCSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.93981 0 0 0 0 0 0 0 0 Q86SG2 ANR23_HUMAN Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3) ANKRD23 DARP Homo sapiens (Human) fatty acid metabolic process [GO:0006631]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of sarcomere organization [GO:0060297]; response to muscle stretch [GO:0035994] actin cytoskeleton [GO:0015629]; cytosol [GO:0005829]; I band [GO:0031674]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] titin binding [GO:0031432]; transcription cis-regulatory region binding [GO:0000976] 0.80026 0.2392 IGSTPLHVAVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9476 0 0 0 0 0 0 0 Q86SG4 DPCA2_HUMAN Putative Dresden prostate carcinoma protein 2 (D-PCa-2) (High mobility group nucleosome-binding domain-containing protein 2 pseudogene 46) HMGN2P46 C15orf21 Homo sapiens (Human) chromatin organization [GO:0006325] nucleus [GO:0005634] chromatin binding [GO:0003682] 0.93983 -1.3247 GITLQKMEMPKQTR 0 0 0 0 9.49434 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86SG6 NEK8_HUMAN Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8) (Nima-related protein kinase 12a) NEK8 JCK NEK12A Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; protein phosphorylation [GO:0006468]; regulation of hippo signaling [GO:0035330] ciliary base [GO:0097546]; ciliary inversin compartment [GO:0097543]; cilium [GO:0005929]; cytoplasm [GO:0005737]; microtubule organizing center [GO:0005815] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.88264 -0.30001 QIPVEQMTK 0 0 0 9.23537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1933 0 0 0 0 0 0 0 0 Q86SH2 ZAR1_HUMAN Zygote arrest protein 1 ZAR1 Homo sapiens (Human) mRNA stabilization [GO:0048255]; negative regulation of translation [GO:0017148]; non-membrane-bounded organelle assembly [GO:0140694]; oocyte maturation [GO:0001556]; translation [GO:0006412] cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; intracellular non-membrane-bounded organelle [GO:0043232] metal ion binding [GO:0046872]; molecular condensate scaffold activity [GO:0140693]; mRNA 3'-UTR binding [GO:0003730]; RNA sequestering activity [GO:0140610]; translation regulator activity [GO:0045182] 0.89043 -0.47968 EAAVAGEGPSPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.9461 0 10.4739 0 0 0 0 0 0 0 0 Q86SJ2 AMGO2_HUMAN Amphoterin-induced protein 2 (AMIGO-2) (Alivin-1) (Differentially expressed in gastric adenocarcinomas) (DEGA) AMIGO2 ALI1 Homo sapiens (Human) brain development [GO:0007420]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of programmed cell death [GO:0043069]; positive regulation of synapse assembly [GO:0051965] nucleus [GO:0005634]; plasma membrane [GO:0005886] 0.59087 0.4618 LDLSYNR 0 0 0 0 10.3405 0 10.8083 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86SJ6 DSG4_HUMAN Desmoglein-4 (Cadherin family member 13) DSG4 CDHF13 Homo sapiens (Human) BMP signaling pathway [GO:0030509]; cell-cell adhesion [GO:0098609]; hair follicle development [GO:0001942]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte differentiation [GO:0030216] cornified envelope [GO:0001533]; desmosome [GO:0030057]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.84224 0.14975 IVSQEPSGAPMFILNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.452 Q86SP6 GP149_HUMAN Probable G-protein coupled receptor 149 (G-protein coupled receptor PGR10) GPR149 PGR10 Homo sapiens (Human) antral ovarian follicle growth [GO:0001547]; negative regulation of ovulation [GO:0060280]; neuropeptide signaling pathway [GO:0007218]; preantral ovarian follicle growth [GO:0001546] neuron projection [GO:0043005]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930] 0.91561 -0.80803 GINKCTNTDITEAK 0 0 0 9.2775 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86SQ0 PHLB2_HUMAN Pleckstrin homology-like domain family B member 2 (Protein LL5-beta) PHLDB2 LL5B Homo sapiens (Human) "cell migration [GO:0016477]; establishment of cell polarity [GO:0030010]; establishment of protein localization [GO:0045184]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of microtubule cytoskeleton organization [GO:0070507]" basal cortex [GO:0045180]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; intermediate filament cytoskeleton [GO:0045111]; plasma membrane [GO:0005886] cadherin binding [GO:0045296] 0.96857 -3.3218 DSESRRMLR 0 0 0 9.48154 0 9.09587 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86SQ4 AGRG6_HUMAN Adhesion G-protein coupled receptor G6 (Developmentally regulated G-protein-coupled receptor) (G-protein coupled receptor 126) (Vascular inducible G protein-coupled receptor) [Cleaved into: ADGRG6 N-terminal fragment (ADGRG6-NTF); ADGRG6 C-terminal fragment (ADGRG6-CTF)] ADGRG6 DREG GPR126 VIGR Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP-mediated signaling [GO:0019933]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186]; heart trabecula formation [GO:0060347]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; nervous system development [GO:0007399]; Schwann cell differentiation [GO:0014037] cell surface [GO:0009986]; cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886] collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; extracellular matrix binding [GO:0050840]; G protein-coupled receptor activity [GO:0004930]; laminin binding [GO:0043236] 0.96771 -2.9055 ILSNLSCNVK 0 13.3019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.0659 0 0 9.49671 0 0 0 0 11.029 0 0 Q86SQ7 SDCG8_HUMAN Serologically defined colon cancer antigen 8 (Antigen NY-CO-8) (Centrosomal colon cancer autoantigen protein) (hCCCAP) SDCCAG8 CCCAP NPHP10 HSPC085 Homo sapiens (Human) cell projection organization [GO:0030030]; centrosome cycle [GO:0007098]; establishment of cell polarity [GO:0030010]; microtubule organizing center organization [GO:0031023]; neuron migration [GO:0001764]; regulation of cilium assembly [GO:1902017]; tube formation [GO:0035148] cell-cell junction [GO:0005911]; centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytosol [GO:0005829]; photoreceptor cell cilium [GO:0097733] 0.96964 -4.0333 DLEIKDQEIEK 0 0 0 0 0 0 0 0 9.42057 0 0 0 9.25238 0 0 10.8701 0 10.1998 0 0 0 0 0 0 10.5901 10.4152 12.2146 Q86SQ9 DHDDS_HUMAN Dehydrodolichyl diphosphate synthase complex subunit DHDDS (EC 2.5.1.87) (Cis-isoprenyltransferase) (CIT) (Cis-IPTase) (Cis-prenyltransferase subunit hCIT) (Epididymis tissue protein Li 189m) DHDDS HDS Homo sapiens (Human) dolichyl diphosphate biosynthetic process [GO:0006489]; polyprenol biosynthetic process [GO:0016094] dehydrodolichyl diphosphate synthase complex [GO:1904423]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789] dehydrodolichyl diphosphate synthase activity [GO:0045547]; metal ion binding [GO:0046872] 0.96928 -3.4179 FSRLMEEK 0 0 0 0 9.26155 0 0 9.17185 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.96665 0 0 Q86SS6 SYT9_HUMAN Synaptotagmin-9 (Synaptotagmin IX) (SytIX) SYT9 Homo sapiens (Human) calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of insulin secretion [GO:0050796] clathrin-coated endocytic vesicle membrane [GO:0030669]; dense core granule [GO:0031045]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; synaptic vesicle membrane [GO:0030672] "calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; SNARE binding [GO:0000149]" 0.88708 -0.34655 AVNLPAK 0 0 0 9.59421 0 0 11.3787 0 11.2912 0 11.4753 0 0 0 0 11.354 0 0 0 0 0 0 0 0 0 0 0 Q86SX3 TEDC1_HUMAN Tubulin epsilon and delta complex protein 1 TEDC1 C14orf80 Homo sapiens (Human) positive regulation of smoothened signaling pathway [GO:0045880] centriole [GO:0005814]; cilium [GO:0005929]; cytoplasm [GO:0005737] 0.92156 -1.0879 LEAVLAWR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.71831 0 0 0 Q86T03 PP4P1_HUMAN "Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase (Type 1 PtdIns-4,5-P2 4-Ptase) (EC 3.1.3.78) (PtdIns-4,5-P2 4-Ptase I) (Transmembrane protein 55B)" PIP4P1 C14orf9 TMEM55B Homo sapiens (Human) cholesterol metabolic process [GO:0008203]; lysosome localization [GO:0032418]; phosphatidylinositol dephosphorylation [GO:0046856]; phospholipid metabolic process [GO:0006644]; positive regulation of TORC1 signaling [GO:1904263]; proton-transporting V-type ATPase complex assembly [GO:0070070]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to sterol depletion [GO:0006991] late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; nucleoplasm [GO:0005654]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886] "phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity [GO:0034597]" 0.78215 0.25282 IACPRPYCK 0 0 0 0 0 0 10.5836 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6205 Q86T13 CLC14_HUMAN C-type lectin domain family 14 member A (Epidermal growth factor receptor 5) (EGFR-5) CLEC14A C14orf27 EGFR5 UNQ236/PRO269 Homo sapiens (Human) cell migration [GO:0016477]; cell migration involved in sprouting angiogenesis [GO:0002042]; lymphangiogenesis [GO:0001946]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324]; vascular endothelial growth factor receptor-3 signaling pathway [GO:0036325] collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897] carbohydrate binding [GO:0030246]; extracellular matrix binding [GO:0050840]; extracellular matrix protein binding [GO:1990430] 0.49951 0.61136 DLLFWVALERR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4338 0 Q86T23 CROL1_HUMAN Putative ciliary rootlet coiled-coil protein-like 1 protein (Ciliary rootlet coiled-coil protein pseudogene 2) CROCCP2 CROCCL1 Homo sapiens (Human) 0.87016 0.046048 LDLNCLVTQLEEEK 0 0 0 0 0 0 0 0 0 0 10.6746 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86T24 KAISO_HUMAN Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33) ZBTB33 KAISO ZNF348 Homo sapiens (Human) intracellular signal transduction [GO:0035556]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of cytokine production [GO:0001817]; regulation of immune system process [GO:0002682]; Wnt signaling pathway [GO:0016055] chromatin [GO:0000785]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; methyl-CpG binding [GO:0008327]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.46457 0.63292 DDPDEGEAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.25382 0 0 0 Q86T65 DAAM2_HUMAN Disheveled-associated activator of morphogenesis 2 DAAM2 KIAA0381 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; determination of left/right symmetry [GO:0007368]; dorsal spinal cord development [GO:0021516]; negative regulation of oligodendrocyte differentiation [GO:0048715]; podocyte cell migration [GO:0090521]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin filament polymerization [GO:0030833]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of filopodium assembly [GO:0051489]; regulation of non-canonical Wnt signaling pathway [GO:2000050]; Wnt signaling pathway [GO:0016055] extracellular exosome [GO:0070062] actin binding [GO:0003779]; small GTPase binding [GO:0031267] 0.96832 -8.834 AINRLNY 0 0 0 0 0 0 0 0 0 8.18036 10.2722 11.0242 0 0 9.94797 9.33847 0 11.6684 0 0 11.4355 0 0 8.73101 0 8.50363 0 Q86T82 UBP37_HUMAN Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.4.19.12) (Deubiquitinating enzyme 37) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) USP37 KIAA1594 Homo sapiens (Human) cell division [GO:0051301]; G1/S transition of mitotic cell cycle [GO:0000082]; protein deubiquitination [GO:0016579]; protein K11-linked deubiquitination [GO:0035871]; protein K48-linked deubiquitination [GO:0071108]; regulation of DNA replication [GO:0006275]; ubiquitin-dependent protein catabolic process [GO:0006511] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] cysteine-type deubiquitinase activity [GO:0004843]; cysteine-type endopeptidase activity [GO:0004197]; protein kinase binding [GO:0019901] 0.76091 0.29167 FSGYMQNDAHEFLSQCLDQLKEDMEK 0 10.2374 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86T90 K1328_HUMAN Protein hinderin KIAA1328 Homo sapiens (Human) 0.96857 -3.8609 LDYNCLLK 0 0 0 0 0 0 0 0 8.51554 10.1808 0 10.5011 0 0 0 11.2771 0 0 0 11.1862 9.22156 0 0 9.87828 0 0 0 Q86T96 RN180_HUMAN E3 ubiquitin-protein ligase RNF180 (EC 2.3.2.27) (RING finger protein 180) (RING-type E3 ubiquitin transferase RNF180) RNF180 Homo sapiens (Human) adult behavior [GO:0030534]; norepinephrine metabolic process [GO:0042415]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; protein polyubiquitination [GO:0000209]; regulation of catalytic activity [GO:0050790]; serotonin metabolic process [GO:0042428] endoplasmic reticulum membrane [GO:0005789]; nuclear envelope [GO:0005635] metal ion binding [GO:0046872]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630] 0.88095 -0.027608 LNCPFCGAR 0 0 0 0 0 0 10.1003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86TA1 MOB3B_HUMAN MOB kinase activator 3B (Mob1 homolog 2b) (Mps one binder kinase activator-like 2B) (MOB kinase activator-like 2B) MOB3B C9orf35 MOBKL2B Homo sapiens (Human) positive regulation of protein phosphorylation [GO:0001934]; regulation of hippo signaling [GO:0035330]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; nucleus [GO:0005634] metal ion binding [GO:0046872]; protein kinase activator activity [GO:0030295] 0.94736 -1.3473 KILCRLFR 0 0 0 0 0 0 0 0 0 0 0 0 12.3632 0 0 0 0 0 0 0 0 0 0 10.206 0 0 0 Q86TB3 ALPK2_HUMAN Alpha-protein kinase 2 (EC 2.7.11.1) (Heart alpha-protein kinase) ALPK2 HAK Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; epicardium morphogenesis [GO:1905223]; establishment of cell polarity [GO:0030010]; heart morphogenesis [GO:0003007]; negative regulation of Wnt signaling pathway involved in heart development [GO:0003308]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468] basolateral plasma membrane [GO:0016323] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96946 -6.0408 EEFASDNLLNMDESVRETEMK 0 0 0 0 9.40013 0 0 0 0 10.5377 0 10.1039 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86TB9 PATL1_HUMAN Protein PAT1 homolog 1 (PAT1-like protein 1) (Protein PAT1 homolog b) (Pat1b) (hPat1b) PATL1 OK/KNS-cl.5 Homo sapiens (Human) deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; P-body assembly [GO:0033962] cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; P-body [GO:0000932]; PML body [GO:0016605] poly(G) binding [GO:0034046]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723] 0.63082 0.4072 NLNGAGDR 0 0 8.7038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86TC9 MYPN_HUMAN Myopalladin (145 kDa sarcomeric protein) MYPN MYOP Homo sapiens (Human) axon guidance [GO:0007411]; dendrite self-avoidance [GO:0070593]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; sarcomere organization [GO:0045214] axon [GO:0030424]; cytosol [GO:0005829]; I band [GO:0031674]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; Z disc [GO:0030018] actin binding [GO:0003779]; cell-cell adhesion mediator activity [GO:0098632]; cytoskeletal protein binding [GO:0008092]; muscle alpha-actinin binding [GO:0051371]; SH3 domain binding [GO:0017124] 0.96931 -3.0279 FTQKLRSR 0 0 0 0 0 14.1886 15.4713 0 0 15.018 9.38511 0 12.6166 12.7217 12.8092 0 0 13.6176 0 9.82303 0 0 0 0 0 0 10.4427 Q86TE4 LUZP2_HUMAN Leucine zipper protein 2 LUZP2 UNQ2566/PRO6246 Homo sapiens (Human) extracellular region [GO:0005576] 0.88223 -0.07293 DLQNENKSLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4199 0 0 0 0 0 0 0 0 0 0 Q86TG7 PEG10_HUMAN Retrotransposon-derived protein PEG10 (Embryonal carcinoma differentiation-regulated protein) (Mammalian retrotransposon-derived protein 2) (Myelin expression factor 3-like protein 1) (MEF3-like protein 1) (Paternally expressed gene 10 protein) (Retrotransposon gag domain-containing protein 3) (Retrotransposon-derived gag-like polyprotein) (Ty3/Gypsy-like protein) PEG10 EDR KIAA1051e MAR2 MART2 MEF3L1 RGAG3 Homo sapiens (Human) apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; mRNA transport [GO:0051028]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; protein homooligomerization [GO:0051260]; vesicle-mediated intercellular transport [GO:0110077] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular vesicle [GO:1903561]; membrane [GO:0016020]; nucleoplasm [GO:0005654] DNA binding [GO:0003677]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270] 0.93243 -1.2634 AARWASAK 0 0 0 0 0 0 0 0 0 0 0 0 8.05121 8.33302 0 0 10.1864 0 0 0 0 0 0 0 0 0 0 Q86TH1 ATL2_HUMAN ADAMTS-like protein 2 (ADAMTSL-2) ADAMTSL2 KIAA0605 Homo sapiens (Human) extracellular matrix organization [GO:0030198]; lobar bronchus epithelium development [GO:0060481]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512] extracellular matrix [GO:0031012]; extracellular region [GO:0005576] microfibril binding [GO:0050436] 0.92031 -0.91791 GVCVSGK 0 0 0 0 0 0 9.09154 0 0 0 0 0 0 0 0 0 0 0 0 9.00073 8.7708 0 0 8.86583 0 0 9.57907 Q86TI0 TBCD1_HUMAN TBC1 domain family member 1 TBC1D1 KIAA1108 Homo sapiens (Human) activation of GTPase activity [GO:0090630] nucleus [GO:0005634] GTPase activator activity [GO:0005096] 0.91322 -0.76235 CLYEEKQK 0 0 0 10.9559 0 0 0 10.6466 0 0 0 0 0 10.8612 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86TI4 WDR86_HUMAN WD repeat-containing protein 86 WDR86 Homo sapiens (Human) 0.77146 0.26975 GAPRPPPPMR 0 0 0 9.19712 9.34014 0 0 0 0 0 8.95977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86TJ5 ZN554_HUMAN Zinc finger protein 554 ZNF554 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleolus [GO:0005730]; nucleoplasm [GO:0005654] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.96944 -3.4032 EALWIEEK 0 0 0 0 0 0 0 0 0 0 0 0 8.83958 0 0 0 0 9.21914 0 9.86405 0 0 0 0 0 0 0 Q86TL2 STIMA_HUMAN Store-operated calcium entry regulator STIMATE (STIM-activating enhancer encoded by TMEM110) (Transmembrane protein 110) STIMATE TMEM110 Homo sapiens (Human) activation of store-operated calcium channel activity [GO:0032237]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886] cortical endoplasmic reticulum [GO:0032541]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-plasma membrane contact site [GO:0140268]; membrane [GO:0016020] calcium channel regulator activity [GO:0005246] 0.70006 0.37127 EPKHERRPWR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.03612 0 0 0 0 0 0 0 0 0 0 0 0 Q86TM3 DDX53_HUMAN Probable ATP-dependent RNA helicase DDX53 (EC 3.6.4.13) (Cancer-associated gene protein) (Cancer/testis antigen 26) (CT26) (DEAD box protein 53) (DEAD box protein CAGE) DDX53 CAGE Homo sapiens (Human) cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.94117 -1.3163 SICIYGGRNR 9.28061 9.30834 9.1165 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86TN4 TRPT1_HUMAN tRNA 2'-phosphotransferase 1 (EC 2.7.1.160) TRPT1 Homo sapiens (Human) "regulation of protein kinase activity [GO:0045859]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]" tRNA 2'-phosphotransferase activity [GO:0000215] 0.89968 -0.68811 QEAAGSRGRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7803 0 0 0 0 Q86TS9 RM52_HUMAN "Large ribosomal subunit protein mL52 (39S ribosomal protein L52, mitochondrial) (L52mt) (MRP-L52)" MRPL52 Homo sapiens (Human) mitochondrial translation [GO:0032543]; translation [GO:0006412] mitochondrial inner membrane [GO:0005743]; mitochondrial large ribosomal subunit [GO:0005762]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] structural constituent of ribosome [GO:0003735] 0.93359 -1.2809 AERETFAR 0 0 0 0 0 0 0 0 0 0 0 0 9.95411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86TU6 CN070_HUMAN Putative uncharacterized protein encoded by LINC00523 LINC00523 C14orf70 Homo sapiens (Human) 0.96406 -2.4194 DEEKLRYIK 0 0 0 0 0 0 0 0 0 0 9.15899 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86TU7 SETD3_HUMAN Actin-histidine N-methyltransferase (EC 2.1.1.85) (Protein-L-histidine N-tele-methyltransferase) (SET domain-containing protein 3) (hSETD3) SETD3 C14orf154 Homo sapiens (Human) actin modification [GO:0030047]; peptidyl-histidine methylation [GO:0018021]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of uterine smooth muscle contraction [GO:0070472] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654] actin binding [GO:0003779]; histone H3K36 methyltransferase activity [GO:0046975]; histone H3K4 methyltransferase activity [GO:0042800]; protein-L-histidine N-tele-methyltransferase activity [GO:0018064]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription coactivator activity [GO:0003713] 0.80993 0.22589 LLMTVESAK 0 9.58082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86TV6 TTC7B_HUMAN Tetratricopeptide repeat protein 7B (TPR repeat protein 7B) (Tetratricopeptide repeat protein 7-like-1) (TPR repeat protein 7-like-1) TTC7B TTC7L1 Homo sapiens (Human) phosphatidylinositol phosphate biosynthetic process [GO:0046854]; protein localization to plasma membrane [GO:0072659] cytosol [GO:0005829]; plasma membrane [GO:0005886] 0.88565 -0.29213 HLTAALDRGNLK 0 0 0 0 0 0 0 0 0 0 0 8.56079 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86TW2 ADCK1_HUMAN AarF domain-containing protein kinase 1 (EC 2.7.-.-) ADCK1 Homo sapiens (Human) lipid homeostasis [GO:0055088]; mitochondrion organization [GO:0007005]; negative regulation of mitochondrial fusion [GO:0010637]; phosphorylation [GO:0016310]; positive regulation of cristae formation [GO:1903852] extracellular region [GO:0005576]; mitochondrial inner membrane [GO:0005743] ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674] 0.96471 -2.6948 AVLHDGRTVAVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.04232 0 10.5022 0 0 0 0 0 Q86TZ1 TTC6_HUMAN Tetratricopeptide repeat protein 6 (TPR repeat protein 6) TTC6 C14orf25 NCRNA00291 Homo sapiens (Human) 0.96371 -2.6512 AITNTILKKYEEAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4389 0 0 0 0 11.1635 0 10.6434 0 Q86U06 RBM23_HUMAN Probable RNA-binding protein 23 (CAPER beta) (CAPERbeta) (RNA-binding motif protein 23) (RNA-binding region-containing protein 4) (Splicing factor SF2) RBM23 RNPC4 PP239 Homo sapiens (Human) "mRNA processing [GO:0006397]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of mRNA splicing, via spliceosome [GO:0048024]; RNA splicing [GO:0008380]" membrane [GO:0016020]; nucleus [GO:0005634] RNA binding [GO:0003723]; U1 snRNP binding [GO:1990446] 0.94095 -1.3164 EPVDNLSPEER 0 0 0 8.74413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86U42 PABP2_HUMAN Polyadenylate-binding protein 2 (PABP-2) (Poly(A)-binding protein 2) (Nuclear poly(A)-binding protein 1) (Poly(A)-binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) PABPN1 PAB2 PABP2 Homo sapiens (Human) cellular response to lipopolysaccharide [GO:0071222]; MAPK cascade [GO:0000165]; mRNA processing [GO:0006397]; muscle contraction [GO:0006936]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of polynucleotide adenylyltransferase activity [GO:1904247]; RNA processing [GO:0006396] cytoplasm [GO:0005737]; nuclear inclusion body [GO:0042405]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; RNA polymerase binding [GO:0070063] 0 18.612 AAAAAAAAAAGAAGGR 0 0 0 9.55538 0 0 0 9.20667 9.29554 0 0 0 0 0 0 0 0 0 0 0 0 10.097 8.7137 8.60933 0 0 0 Q86U44 MTA70_HUMAN N6-adenosine-methyltransferase catalytic subunit (EC 2.1.1.348) (Methyltransferase-like protein 3) (hMETTL3) (N6-adenosine-methyltransferase 70 kDa subunit) (MT-A70) METTL3 MTA70 Homo sapiens (Human) "adenosine to inosine editing [GO:0006382]; cellular response to UV [GO:0034644]; circadian rhythm [GO:0007623]; DNA damage response [GO:0006974]; dosage compensation by inactivation of X chromosome [GO:0009048]; endothelial to hematopoietic transition [GO:0098508]; forebrain radial glial cell differentiation [GO:0021861]; gliogenesis [GO:0042063]; innate immune response [GO:0045087]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; mRNA methylation [GO:0080009]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; oogenesis [GO:0048477]; positive regulation of cap-independent translational initiation [GO:1903679]; positive regulation of translation [GO:0045727]; primary miRNA processing [GO:0031053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of meiotic cell cycle [GO:0051445]; regulation of T cell differentiation [GO:0045580]; RNA methylation [GO:0001510]; spermatogenesis [GO:0007283]; stem cell population maintenance [GO:0019827]" cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nuclear body [GO:0016604]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA N6-methyladenosine methyltransferase complex [GO:0036396] mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity [GO:0016422]; mRNA (N6-adenosine)-methyltransferase activity [GO:0001734]; mRNA binding [GO:0003729]; protein heterodimerization activity [GO:0046982]; RNA methyltransferase activity [GO:0008173]; S-adenosyl-L-methionine binding [GO:1904047] 0.96205 -2.5534 LSAMMGAVAEKK 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4115 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86U86 PB1_HUMAN Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D) PBRM1 BAF180 PB1 Homo sapiens (Human) chromatin remodeling [GO:0006338]; mitotic cell cycle [GO:0000278]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cell differentiation [GO:0045597]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of T cell differentiation [GO:0045582]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription elongation by RNA polymerase II [GO:0006368] chromatin [GO:0000785]; kinetochore [GO:0000776]; nuclear chromosome [GO:0000228]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RSC-type complex [GO:0016586]; SWI/SNF complex [GO:0016514] chromatin binding [GO:0003682]; DNA binding [GO:0003677] 0.96408 -2.4033 AEYEERAAK 0 0 0 0 0 0 12.6389 10.6884 0 9.07836 0 0 11.8298 0 0 0 9.91924 0 9.1815 9.33517 0 9.97427 10.0133 0 10.5033 11.6435 10.4454 Q86UA1 PRP39_HUMAN Pre-mRNA-processing factor 39 (PRP39 homolog) PRPF39 Homo sapiens (Human) mRNA 5'-splice site recognition [GO:0000395] commitment complex [GO:0000243]; U1 snRNP [GO:0005685]; U2-type prespliceosome [GO:0071004] 0.77693 0.2648 LLNAYDEHQTLLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5436 0 9.50535 Q86UA6 RIP_HUMAN RPA-interacting protein (hRIP) RPAIN RIP Homo sapiens (Human) protein import into nucleus [GO:0006606]; response to UV [GO:0009411] cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605] metal ion binding [GO:0046872] 0.95099 -1.3838 LVGSPPWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.17105 0 Q86UB2 BIVM_HUMAN Basic immunoglobulin-like variable motif-containing protein BIVM Homo sapiens (Human) cytoplasm [GO:0005737]; extracellular space [GO:0005615]; nucleus [GO:0005634] 0.58988 0.45831 FGPFTGNTTLMR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.92704 0 0 Q86UB9 TM135_HUMAN Transmembrane protein 135 (Peroxisomal membrane protein 52) (PMP52) TMEM135 Homo sapiens (Human) mitochondrion morphogenesis [GO:0070584]; peroxisome organization [GO:0007031]; regulation of mitochondrial fission [GO:0090140]; regulation of oxidative phosphorylation [GO:0002082]; response to cold [GO:0009409]; response to food [GO:0032094]; retinal pigment epithelium development [GO:0003406] lipid droplet [GO:0005811]; mitochondrial membrane [GO:0031966]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777] 0.91349 -0.76208 REQHEEKPGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2953 0 0 0 0 0 0 0 0 0 0 0 0 Q86UC2 RSPH3_HUMAN Radial spoke head protein 3 homolog (A-kinase anchor protein RSPH3) (Radial spoke head-like protein 2) RSPH3 RSHL2 RSP3 Homo sapiens (Human) cilium [GO:0005929]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; motile cilium [GO:0031514] 0.92174 -1.0898 AASLARNLAK 10.0626 0 0 0 16.2025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86UD3 MARH3_HUMAN E3 ubiquitin-protein ligase MARCHF3 (EC 2.3.2.27) (Membrane-associated RING finger protein 3) (Membrane-associated RING-CH protein III) (MARCH-III) (RING finger protein 173) (RING-type E3 ubiquitin transferase MARCHF3) MARCHF3 MARCH3 RNF173 Homo sapiens (Human) endocytosis [GO:0006897]; protein ubiquitination [GO:0016567] early endosome membrane [GO:0031901]; endosome [GO:0005768]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764] ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.9169 -0.7664 LYNEWRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1098 0 0 0 0 0 0 0 0 Q86UE6 LRRT1_HUMAN Leucine-rich repeat transmembrane neuronal protein 1 LRRTM1 UNQ675/PRO1309 Homo sapiens (Human) establishment of localization in cell [GO:0051649]; exploration behavior [GO:0035640]; locomotory behavior [GO:0007626]; long-term synaptic potentiation [GO:0060291]; negative regulation of receptor internalization [GO:0002091]; positive regulation of synapse assembly [GO:0051965]; protein localization to synapse [GO:0035418]; receptor internalization [GO:0031623]; synapse organization [GO:0050808] axon [GO:0030424]; endoplasmic reticulum [GO:0005783]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; GABA-ergic synapse [GO:0098982]; growth cone [GO:0030426]; postsynaptic specialization membrane [GO:0099634] 0.87923 -0.015135 VNFAHFPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.91525 0 0 0 0 Q86UE8 TLK2_HUMAN Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (HsHPK) (PKU-alpha) (Tousled-like kinase 2) TLK2 Homo sapiens (Human) cellular response to gamma radiation [GO:0071480]; chromatin organization [GO:0006325]; chromosome segregation [GO:0007059]; DNA damage response [GO:0006974]; intracellular signal transduction [GO:0035556]; localization [GO:0051179]; negative regulation of autophagy [GO:0010507]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]; regulation of chromatin organization [GO:1902275] intermediate filament [GO:0005882]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] ATP binding [GO:0005524]; identical protein binding [GO:0042802]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96001 -1.9433 ELKRIHNEDNSQFK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4437 0 0 0 0 0 0 0 0 0 0 0 9.3168 0 Q86UF4 CC190_HUMAN Coiled-coil domain-containing protein 190 CCDC190 C1orf110 Homo sapiens (Human) 0.62998 0.40258 LLTWEQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.533 0 0 0 11.0329 0 0 0 0 0 0 0 0 Q86UG4 SO6A1_HUMAN Solute carrier organic anion transporter family member 6A1 (Cancer/testis antigen 48) (CT48) (Gonad-specific transporter) (GST) (Organic anion-transporting polypeptide 6A1) (Organic anion-transporting polypeptide I) (OATP-I) (Solute carrier family 21 member 19) SLCO6A1 OATP6A1 SLC21A19 Homo sapiens (Human) sodium-independent organic anion transport [GO:0043252] plasma membrane [GO:0005886] sodium-independent organic anion transmembrane transporter activity [GO:0015347] 0.93022 -1.2358 GVEPLEAAR 0 10.2875 0 9.59872 0 0 0 0 0 9.63456 0 0 0 0 0 9.00121 0 0 0 9.32425 0 0 0 0 0 0 0 Q86UK5 LBN_HUMAN Limbin (Ellis-van Creveld syndrome protein 2) (EVC2) EVC2 LBN Homo sapiens (Human) smoothened signaling pathway [GO:0007224] ciliary membrane [GO:0060170]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; nucleus [GO:0005634]; plasma membrane protein complex [GO:0098797] 0.92573 -0.9578 LASYLAR 0 0 0 0 0 10.438 0 12.0436 0 0 0 0 0 0 0 0 9.96245 10.1594 0 0 0 0 0 0 0 0 0 Q86UK7 ZN598_HUMAN E3 ubiquitin-protein ligase ZNF598 (EC 2.3.2.27) (Zinc finger protein 598) ZNF598 Homo sapiens (Human) protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]; regulation of translation [GO:0006417]; rescue of stalled ribosome [GO:0072344]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] cytosol [GO:0005829]; cytosolic ribosome [GO:0022626] metal ion binding [GO:0046872]; ribosome binding [GO:0043022]; RNA binding [GO:0003723]; stalled ribosome sensor activity [GO:0170011]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activator activity [GO:0097027] 0.29515 0.81715 CDHPVCYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5514 0 0 0 0 0 0 0 0 0 Q86UL8 MAGI2_HUMAN "Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Atrophin-1-interacting protein 1) (AIP-1) (Atrophin-1-interacting protein A) (Membrane-associated guanylate kinase inverted 2) (MAGI-2)" MAGI2 ACVRINP1 AIP1 KIAA0705 Homo sapiens (Human) cellular response to nerve growth factor stimulus [GO:1990090]; clathrin-dependent endocytosis [GO:0072583]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase B signaling [GO:0051898]; nerve growth factor signaling pathway [GO:0038180]; nervous system development [GO:0007399]; planar cell polarity pathway involved in axis elongation [GO:0003402]; podocyte development [GO:0072015]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of receptor internalization [GO:0002092]; receptor clustering [GO:0043113]; signal transduction [GO:0007165]; SMAD protein signal transduction [GO:0060395] bicellular tight junction [GO:0005923]; centriole [GO:0005814]; ciliary base [GO:0097546]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; late endosome [GO:0005770]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; slit diaphragm [GO:0036057]; synapse [GO:0045202] beta-1 adrenergic receptor binding [GO:0031697]; phosphatase binding [GO:0019902]; signaling receptor complex adaptor activity [GO:0030159]; SMAD binding [GO:0046332]; type II activin receptor binding [GO:0070699] 0.88477 -0.28541 EGEVPGVDYIFITVEDFMELEK 0 0 0 0 0 0 10.2194 0 0 0 10.1352 0 0 0 0 0 0 0 0 0 0 0 8.78738 0 10.3987 0 0 Q86UP2 KTN1_HUMAN Kinectin (CG-1 antigen) (Kinesin receptor) KTN1 CG1 KIAA0004 Homo sapiens (Human) microtubule-based movement [GO:0007018]; protein transport [GO:0015031] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886] cadherin binding [GO:0045296]; kinesin binding [GO:0019894]; RNA binding [GO:0003723] 0.96934 -6.2473 CIQEKDEK 9.61862 0 12.4054 9.60021 9.68785 0 11.1901 11.1067 10.9569 0 0 0 0 0 11.4296 0 0 0 0 10.0293 0 0 0 0 8.08561 9.34139 0 Q86UP3 ZFHX4_HUMAN Zinc finger homeobox protein 4 (Zinc finger homeodomain protein 4) (ZFH-4) ZFHX4 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; zinc ion binding [GO:0008270]" 0.9693 -7.4126 ASGSVASNYGISGK 8.87879 0 8.8867 0 0 0 11.2778 10.2754 10.3417 9.91163 12.8646 9.70962 11.0717 0 0 0 11.482 10.237 0 0 0 0 0 0 0 0 0 Q86UP8 GTD2A_HUMAN General transcription factor II-I repeat domain-containing protein 2A (GTF2I repeat domain-containing protein 2A) (Transcription factor GTF2IRD2-alpha) GTF2IRD2 GTF2IRD2A Homo sapiens (Human) nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]" 0.96949 -3.9816 DEKLHELK 9.86412 0 0 0 0 0 0 0 0 0 11.5383 0 0 0 0 10.9335 0 0 0 0 0 0 0 0 0 0 0 Q86UQ4 ABCAD_HUMAN ATP-binding cassette sub-family A member 13 (EC 7.6.2.-) ABCA13 Homo sapiens (Human) ceramide transport [GO:0035627]; lipid transport [GO:0006869]; positive regulation of cholesterol transport [GO:0032376]; positive regulation of synaptic vesicle endocytosis [GO:1900244] azurophil granule membrane [GO:0035577]; intracellular membrane-bounded organelle [GO:0043231]; intracellular vesicle [GO:0097708]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667] ABC-type transporter activity [GO:0140359]; ATP binding [GO:0005524]; ATPase-coupled transmembrane transporter activity [GO:0042626]; lipid transporter activity [GO:0005319] 0.8845 -0.14059 DILCATLSCK 10.1252 0 0 0 8.88667 0 0 9.9714 11.1917 0 11.3921 0 0 0 0 0 0 0 0 0 9.78436 0 9.34775 0 0 0 0 Q86UR1 NOXA1_HUMAN NADPH oxidase activator 1 (NOX activator 1) (Antigen NY-CO-31) (NCF2-like protein) (P67phox-like factor) (p51-nox) NOXA1 P51NOX Homo sapiens (Human) regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of respiratory burst [GO:0060263]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801] cytosol [GO:0005829]; NADPH oxidase complex [GO:0043020] enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; SH3 domain binding [GO:0017124]; small GTPase binding [GO:0031267]; superoxide-generating NADPH oxidase activator activity [GO:0016176] 0.96217 -2.5603 MSGAPGR 0 0 0 0 0 0 0 0 0 9.34793 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86UR5 RIMS1_HUMAN Regulating synaptic membrane exocytosis protein 1 (Rab-3-interacting molecule 1) (RIM 1) (Rab-3-interacting protein 2) RIMS1 KIAA0340 RAB3IP2 RIM1 Nbla00761 Homo sapiens (Human) acrosomal vesicle exocytosis [GO:0060478]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; protein-containing complex assembly [GO:0065003]; regulated exocytosis [GO:0045055]; regulation of membrane potential [GO:0042391]; regulation of neurotransmitter secretion [GO:0046928]; regulation of synaptic plasticity [GO:0048167]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to stimulus [GO:0050896]; secretion [GO:0046903]; synaptic vesicle exocytosis [GO:0016079]; visual perception [GO:0007601] cell projection [GO:0042995]; cytoskeleton of presynaptic active zone [GO:0048788]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; presynaptic active zone [GO:0048786]; presynaptic membrane [GO:0042734] GTPase regulator activity [GO:0030695]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; small GTPase binding [GO:0031267]; transmembrane transporter binding [GO:0044325] 0.91974 -0.9015 ATDQPVIR 9.85103 0 0 0 0 0 0 0 9.30193 0 0 11.3863 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86US8 EST1A_HUMAN Telomerase-binding protein EST1A (EC 3.1.-.-) (Ever shorter telomeres 1A) (hEST1A) (Nonsense mediated mRNA decay factor SMG6) (Smg-6 homolog) (hSmg5/7a) SMG6 C17orf31 EST1A KIAA0732 Homo sapiens (Human) "mRNA export from nucleus [GO:0006406]; negative regulation of telomere capping [GO:1904354]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of dephosphorylation [GO:0035303]; regulation of telomerase activity [GO:0051972]; regulation of telomere maintenance [GO:0032204]; regulation of telomere maintenance via telomerase [GO:0032210]" "chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleus [GO:0005634]; telomerase holoenzyme complex [GO:0005697]" DNA polymerase binding [GO:0070182]; metal ion binding [GO:0046872]; ribonucleoprotein complex binding [GO:0043021]; RNA binding [GO:0003723]; RNA endonuclease activity [GO:0004521]; telomerase RNA binding [GO:0070034]; telomeric DNA binding [GO:0042162] 0.95541 -1.5408 DFMPASKEEPIR 0 0 0 0 0 0 0 0 9.43336 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5533 10.0823 8.42072 0 Q86UT5 NHRF4_HUMAN Na(+)/H(+) exchange regulatory cofactor NHE-RF4 (NHERF-4) (Intestinal and kidney-enriched PDZ protein) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (Na/Pi cotransporter C-terminal-associated protein 2) (NaPi-Cap2) (PDZ domain-containing protein 2) (PDZ domain-containing protein 3) (Sodium-hydrogen exchanger regulatory factor 4) NHERF4 IKEPP PDZD3 PDZK2 DLNB27 Homo sapiens (Human) monoatomic ion transport [GO:0006811]; negative regulation of cGMP-mediated signaling [GO:0010754]; protein localization to plasma membrane [GO:0072659]; receptor guanylyl cyclase signaling pathway [GO:0007168]; response to toxic substance [GO:0009636]; water transport [GO:0006833] apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; brush border [GO:0005903]; cytosol [GO:0005829]; plasma membrane [GO:0005886] guanylate cyclase inhibitor activity [GO:0030251]; ion channel inhibitor activity [GO:0008200]; protein-membrane adaptor activity [GO:0043495]; signaling receptor binding [GO:0005102]; ubiquitin-specific protease binding [GO:1990381] 0.84747 0.15662 LQQLPEAEPPLCLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9347 0 0 0 0 0 Q86UT6 NLRX1_HUMAN NLR family member X1 (Caterpiller protein 11.3) (CLR11.3) (Nucleotide-binding oligomerization domain protein 5) (Nucleotide-binding oligomerization domain protein 9) NLRX1 NOD5 NOD9 Homo sapiens (Human) innate immune response [GO:0045087]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of RIG-I signaling pathway [GO:0039536] cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886] ATP binding [GO:0005524] 0.22967 0.85892 FFLAPCVEPGR 0 0 0 0 0 0 0 0 0 0 0 8.32166 0 0 0 0 0 0 0 0 10.0968 0 0 0 0 0 0 Q86UT8 CATAC_HUMAN Centrosomal AT-AC splicing factor (Coiled-coil domain-containing protein 84) CENATAC CCDC84 DLNB14 Homo sapiens (Human) "chromosome separation [GO:0051304]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of centrosome duplication [GO:0010826]; regulation of protein catabolic process [GO:0042176]" centrosome [GO:0005813]; cytoplasm [GO:0005737] 0.7747 0.2655 GLDSYEEK 8.55225 0 8.5129 0 0 0 0 8.33445 0 9.3583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86UU0 BCL9L_HUMAN B-cell CLL/lymphoma 9-like protein (B-cell lymphoma 9-like protein) (BCL9-like protein) (Protein BCL9-2) BCL9L DLNB11 Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; myoblast differentiation [GO:0045445]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell morphogenesis [GO:0022604]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell population maintenance [GO:0035019]; transcription by RNA polymerase II [GO:0006366] beta-catenin-TCF complex [GO:1990907]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] beta-catenin binding [GO:0008013]; transcription coactivator activity [GO:0003713] 0.92268 -1.0585 SLQTLRDIER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4491 0 9.26718 0 0 0 0 Q86UU1 PHLB1_HUMAN Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha) PHLDB1 KIAA0638 LL5A DLNB07 Homo sapiens (Human) positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of microtubule cytoskeleton organization [GO:0070507] basal cortex [GO:0045180]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886] 0.96794 -3.8178 EKLTVLER 0 0 0 11.6055 9.84515 0 0 9.79385 0 0 0 0 0 0 0 0 0 11.1792 0 0 0 10.2947 0 10.1819 0 10.0933 0 Q86UV5 UBP48_HUMAN Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.4.19.12) (Deubiquitinating enzyme 48) (Ubiquitin thioesterase 48) (Ubiquitin-specific peptidase 48) (Ubiquitin-specific protease 48) (Ubiquitin-specific-processing protease 48) USP48 USP31 Homo sapiens (Human) protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] cysteine-type deubiquitinase activity [GO:0004843]; cysteine-type endopeptidase activity [GO:0004197]; deubiquitinase activity [GO:0101005] 0.96799 -3.6841 DPQSGEWYK 0 0 0 0 0 0 0 0 10.0585 10.9817 0 0 9.90654 0 0 0 8.81973 0 0 0 0 0 0 0 0 0 0 Q86UV7 TRI73_HUMAN Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B) TRIM73 TRIM50B Homo sapiens (Human) protein ubiquitination [GO:0016567] cytoplasm [GO:0005737]; cytosol [GO:0005829] ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.88384 -0.10884 IVNESDVFSWVIRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.69087 Q86UW6 N4BP2_HUMAN NEDD4-binding protein 2 (N4BP2) (EC 3.-.-.-) (BCL-3-binding protein) N4BP2 B3BP KIAA1413 Homo sapiens (Human) cytosol [GO:0005829] ATP binding [GO:0005524]; DNA endonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; polydeoxyribonucleotide 5'-hydroxyl-kinase activity [GO:0046404]; ubiquitin binding [GO:0043130] 0.96257 -2.1703 SQCDDASEPLNSYK 0 9.68038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86UW7 CAPS2_HUMAN Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2) CADPS2 CAPS2 KIAA1591 Homo sapiens (Human) dense core granule exocytosis [GO:1990504]; exocytosis [GO:0006887]; positive regulation of exocytosis [GO:0045921]; protein transport [GO:0015031]; synaptic vesicle exocytosis [GO:0016079] cytoplasmic vesicle membrane [GO:0030659]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; presynapse [GO:0098793] lipid binding [GO:0008289]; metal ion binding [GO:0046872] 0.96929 -3.5524 AGGGGAAR 0 0 0 10.6119 10.8541 0 0 9.10852 0 0 0 0 11.1228 11.5317 0 0 0 0 9.65102 0 0 0 0 0 0 0 11.4539 Q86UX2 ITIH5_HUMAN Inter-alpha-trypsin inhibitor heavy chain H5 (ITI heavy chain H5) (ITI-HC5) (Inter-alpha-inhibitor heavy chain 5) ITIH5 KIAA1953 PP14776 UNQ311/PRO354 Homo sapiens (Human) hyaluronan metabolic process [GO:0030212]; negative regulation of peptidase activity [GO:0010466] collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576] serine-type endopeptidase inhibitor activity [GO:0004867] 0.89917 -0.63684 KLDHLHVEVTASNSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.3653 0 0 0 0 0 0 0 0 0 0 Q86UX7 URP2_HUMAN Fermitin family homolog 3 (Kindlin-3) (MIG2-like protein) (Unc-112-related protein 2) FERMT3 KIND3 MIG2B URP2 Homo sapiens (Human) cell-matrix adhesion [GO:0007160]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; platelet aggregation [GO:0070527]; positive regulation of cell migration [GO:0030335]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; substrate adhesion-dependent cell spreading [GO:0034446] cell projection [GO:0042995]; cell-substrate junction [GO:0030055]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; podosome [GO:0002102] integrin binding [GO:0005178]; lipid binding [GO:0008289] 0.89951 -0.64117 IVEQINRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5195 Q86UY8 NT5D3_HUMAN 5'-nucleotidase domain-containing protein 3 (EC 3.1.3.-) (GRP94-neighboring nucleotidase) NT5DC3 GNN TU12B1-TY Homo sapiens (Human) cytosol [GO:0005829]; receptor complex [GO:0043235] 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872] 0.95566 -1.5835 DAESQLVLQEWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.693 0 0 0 0 0 Q86UZ6 ZBT46_HUMAN Zinc finger and BTB domain-containing protein 46 (BTB-ZF protein expressed in effector lymphocytes) (BZEL) (BTB/POZ domain-containing protein 4) (Zinc finger protein 340) ZBTB46 BTBD4 ZNF340 Homo sapiens (Human) granulocyte differentiation [GO:0030851]; macrophage differentiation [GO:0030225]; negative regulation of dendritic cell differentiation [GO:2001199]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of leukocyte activation [GO:0002695]; negative regulation of macrophage differentiation [GO:0045650]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of transcription by RNA polymerase II [GO:0000122]; plasmacytoid dendritic cell differentiation [GO:0002273]; positive regulation of dendritic cell differentiation [GO:2001200]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; transcription cis-regulatory region binding [GO:0000976]" 0.88416 -0.16721 HGVCTDCAGR 9.68452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.18254 0 8.39571 Q86V15 CASZ1_HUMAN Zinc finger protein castor homolog 1 (Castor-related protein) (Putative survival-related protein) (Zinc finger protein 693) CASZ1 CST SRG ZNF693 Homo sapiens (Human) positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of neuron differentiation [GO:0045664] chromatin [GO:0000785]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.96934 -3.159 DGGALEEKDSDGAASK 0 0 0 0 0 0 0 0 0 0 9.57624 0 0 0 10.2011 0 0 0 0 0 9.22289 0 9.68676 0 0 0 0 Q86V20 SHLD2_HUMAN Shieldin complex subunit 2 (Protein FAM35A) (RINN1-REV7-interacting novel NHEJ regulator 2) (Shield complex subunit 2) SHLD2 FAM35A RINN2 Homo sapiens (Human) DNA repair [GO:0006281]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; positive regulation of isotype switching [GO:0045830]; regulation of double-strand break repair via homologous recombination [GO:0010569]; somatic diversification of immunoglobulins involved in immune response [GO:0002208]; telomere maintenance in response to DNA damage [GO:0043247] actin cytoskeleton [GO:0015629]; chromatin [GO:0000785]; chromosome [GO:0005694]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861] 0.89854 -0.55453 NVSEFKSIK 0 0 0 0 0 0 0 0 0 0 0 9.50615 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86V21 AACS_HUMAN Acetoacetyl-CoA synthetase (EC 6.2.1.16) (Acyl-CoA synthetase family member 1) (Protein sur-5 homolog) AACS ACSF1 Homo sapiens (Human) fatty acid metabolic process [GO:0006631]; ketone body biosynthetic process [GO:0046951]; positive regulation of insulin secretion [GO:0032024] cytosol [GO:0005829] acetoacetate-CoA ligase activity [GO:0030729]; ATP binding [GO:0005524] 0.9692 -3.4831 EGKEEIVKVTFEELR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.19805 0 0 8.88344 0 0 0 0 0 0 0 0 Q86V24 PAQR2_HUMAN Adiponectin receptor protein 2 (Progestin and adipoQ receptor family member 2) (Progestin and adipoQ receptor family member II) ADIPOR2 PAQR2 Homo sapiens (Human) adiponectin-activated signaling pathway [GO:0033211]; fatty acid oxidation [GO:0019395]; glucose homeostasis [GO:0042593]; hormone-mediated signaling pathway [GO:0009755]; positive regulation of cold-induced thermogenesis [GO:0120162]; vascular wound healing [GO:0061042] plasma membrane [GO:0005886] adipokinetic hormone receptor activity [GO:0097003]; adiponectin binding [GO:0055100]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; signaling receptor activity [GO:0038023] 0.91858 -0.87899 DNDFLLHGHRPPMPSFRACFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3372 0 0 10.2235 0 0 0 Q86V25 VASH2_HUMAN Tubulinyl-Tyr carboxypeptidase 2 (EC 3.4.17.17) (Vasohibin-2) (Vasohibin-like protein) VASH2 VASHL Homo sapiens (Human) axon development [GO:0061564]; cell-cell fusion [GO:0140253]; labyrinthine layer blood vessel development [GO:0060716]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell proliferation [GO:0001938]; proteolysis [GO:0006508]; regulation of angiogenesis [GO:0045765]; syncytium formation by plasma membrane fusion [GO:0000768] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576] actin binding [GO:0003779]; metallocarboxypeptidase activity [GO:0004181]; microtubule binding [GO:0008017]; tubulin-tyrosine carboxypeptidase [GO:0106423] 0.94358 -1.3348 KVADLSTLNEVGYQIRI 9.45068 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86V48 LUZP1_HUMAN Leucine zipper protein 1 LUZP1 Homo sapiens (Human) artery development [GO:0060840]; neural fold bending [GO:0021503]; ventricular septum development [GO:0003281] centrosome [GO:0005813]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634] 0.96942 -4.7603 AIIKPVIVDK 0 12.1792 0 0 0 0 0 0 0 0 0 9.32035 0 0 0 0 0 10.9838 0 0 0 9.72339 0 9.46314 0 10.049 0 Q86V71 ZN429_HUMAN Zinc finger protein 429 ZNF429 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.91652 -0.84623 RIYVGEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.03144 0 0 0 0 0 Q86V81 THOC4_HUMAN THO complex subunit 4 (Tho4) (Ally of AML-1 and LEF-1) (Aly/REF export factor) (Transcriptional coactivator Aly/REF) (bZIP-enhancing factor BEF) ALYREF ALY BEF THOC4 Homo sapiens (Human) "mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; osteoblast differentiation [GO:0001649]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; regulation of DNA recombination [GO:0000018]; replication fork processing [GO:0031297]; RNA export from nucleus [GO:0006405]; viral mRNA export from host cell nucleus [GO:0046784]" catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription export complex [GO:0000346] C5-methylcytidine-containing RNA binding [GO:0062153]; mRNA binding [GO:0003729]; RNA binding [GO:0003723] 0.63116 0.39866 AGSQGGR 0 0 0 11.1903 11.1311 11.0763 0 0 0 0 0 9.69784 9.27708 0 11.7465 0 0 0 0 0 0 0 9.29655 0 9.85047 0 0 Q86V86 PIM3_HUMAN Serine/threonine-protein kinase pim-3 (EC 2.7.11.1) PIM3 Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; negative regulation of apoptotic process [GO:0043066]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of mitotic cell cycle [GO:0007346] cytoplasm [GO:0005737]; cytosol [GO:0005829] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.5814 0.47182 IADGLPVAVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2929 0 10.3589 0 0 Q86V87 FHI2B_HUMAN FHF complex subunit HOOK-interacting protein 2B (FHIP2B) (Retinoic acid-induced protein 16) FHIP2B FAM160B2 RAI16 FP13191 Homo sapiens (Human) 0.36627 0.74345 ILETLCTLGK 0 0 10.2788 0 0 0 9.64088 0 9.66085 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86V97 KBTB6_HUMAN Kelch repeat and BTB domain-containing protein 6 KBTBD6 Homo sapiens (Human) negative regulation of signal transduction [GO:0009968]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; regulation of Rac protein signal transduction [GO:0035020]; response to unfolded protein [GO:0006986] Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] 0.94015 -1.3015 TPQWKKNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7716 0 0 Q86VB7 C163A_HUMAN Scavenger receptor cysteine-rich type 1 protein M130 (Hemoglobin scavenger receptor) (CD antigen CD163) [Cleaved into: Soluble CD163 (sCD163)] CD163 M130 Homo sapiens (Human) acute-phase response [GO:0006953] cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; plasma membrane [GO:0005886] scaffold protein binding [GO:0097110]; scavenger receptor activity [GO:0005044] 0.96942 -3.1519 EAILSHTEK 0 0 0 0 0 0 0 12.0441 0 0 0 0 0 0 0 0 0 0 0 9.86118 0 0 0 0 0 0 8.75746 Q86VD1 MORC1_HUMAN MORC family CW-type zinc finger protein 1 (Cancer/testis antigen 33) (CT33) MORC1 MORC Homo sapiens (Human) behavioral fear response [GO:0001662]; cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; epigenetic regulation of gene expression [GO:0040029]; negative regulation of DNA-templated transcription initiation [GO:2000143]; negative regulation of transposition [GO:0010529]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283]; transposition [GO:0032196] male germ cell nucleus [GO:0001673]; nucleus [GO:0005634] zinc ion binding [GO:0008270] 0.9697 -5.4194 GAFKDEVK 0 0 0 0 0 0 0 0 0 0 10.8348 9.9928 9.2447 0 0 0 0 0 0 0 0 0 0 0 0 9.61162 0 Q86VD7 S2542_HUMAN Mitochondrial coenzyme A transporter SLC25A42 (Solute carrier family 25 member 42) SLC25A42 Homo sapiens (Human) ADP transport [GO:0015866]; AMP transport [GO:0080121]; ATP transport [GO:0015867]; coenzyme A transmembrane transport [GO:0035349] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; nucleus [GO:0005634] ADP phosphatase activity [GO:0043262]; ADP transmembrane transporter activity [GO:0015217]; AMP transmembrane transporter activity [GO:0080122]; ATP transmembrane transporter activity [GO:0005347]; coenzyme A transmembrane transporter activity [GO:0015228] 0.9541 -1.5143 SLHREYSGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0385 0 Q86VE9 SERC5_HUMAN Serine incorporator 5 SERINC5 C5orf12 Homo sapiens (Human) defense response to virus [GO:0051607]; detection of virus [GO:0009597]; innate immune response [GO:0045087]; L-serine biosynthetic process [GO:0006564]; myelination [GO:0042552]; phosphatidylserine metabolic process [GO:0006658]; phospholipid biosynthetic process [GO:0008654]; positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity [GO:1904219]; positive regulation of serine C-palmitoyltransferase activity [GO:1904222] centrosome [GO:0005813]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] L-serine transmembrane transporter activity [GO:0015194] 0.80505 0.23575 CCFCFSPGGEDTEEQQPGK 0 12.7228 12.8545 0 0 0 0 0 0 12.215 0 0 0 0 0 10.4923 0 0 9.95686 0 0 0 0 0 0 0 0 Q86VF2 IGFN1_HUMAN Immunoglobulin-like and fibronectin type III domain-containing protein 1 (EEF1A2-binding protein 1) (KY-interacting protein 1) IGFN1 EEF1A2BP1 KYIP1 Homo sapiens (Human) nucleus [GO:0005634]; Z disc [GO:0030018] 0.9139 -0.82102 EPQEDLRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.06595 0 0 0 0 Q86VF7 NRAP_HUMAN Nebulin-related-anchoring protein (N-RAP) NRAP Homo sapiens (Human) cardiac muscle thin filament assembly [GO:0071691] fascia adherens [GO:0005916]; muscle tendon junction [GO:0005927]; Z disc [GO:0030018] actin binding [GO:0003779]; actin filament binding [GO:0051015]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]; vinculin binding [GO:0017166] 0.96971 -4.1623 ISCIDQIWHK 0 0 0 0 0 0 0 0 0 9.88518 9.35625 0 0 10.5628 9.60235 10.7048 0 0 0 0 0 0 9.52671 0 10.8922 0 10.4266 Q86VH2 KIF27_HUMAN Kinesin-like protein KIF27 KIF27 Homo sapiens (Human) cilium assembly [GO:0060271]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; microtubule-based movement [GO:0007018]; ventricular system development [GO:0021591] cilium [GO:0005929]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; kinesin complex [GO:0005871]; microtubule [GO:0005874] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777] 0.9695 -4.423 EDEKGNTVIVGAK 0 0 0 0 8.24332 0 0 0 0 0 0 0 0 11.4115 0 0 0 0 0 11.7724 0 9.87823 0 0 0 0 0 Q86VI3 IQGA3_HUMAN Ras GTPase-activating-like protein IQGAP3 IQGAP3 Homo sapiens (Human) cellular response to organic substance [GO:0071310]; ERK1 and ERK2 cascade [GO:0070371]; G1/S transition of mitotic cell cycle [GO:0000082]; gene expression [GO:0010467]; mammary gland epithelial cell proliferation [GO:0033598]; mitotic actomyosin contractile ring assembly actin filament organization [GO:1903479]; negative regulation of gene expression [GO:0010629]; positive regulation of gene expression [GO:0010628]; positive regulation of mammary gland epithelial cell proliferation [GO:0033601]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein phosphorylation [GO:0001934]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087] cell cortex [GO:0005938]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; lateral plasma membrane [GO:0016328] actin filament binding [GO:0051015]; calmodulin binding [GO:0005516]; GTPase activator activity [GO:0005096]; myosin VI light chain binding [GO:0070856]; small GTPase binding [GO:0031267] 0.95313 -1.4849 AQVTGDPGAVLWLEEIR 9.66224 0 9.5434 0 0 0 0 0 0 9.05183 0 0 0 0 0 10.0193 0 0 0 0 9.95517 0 0 0 0 0 0 Q86VK4 ZN410_HUMAN Zinc finger protein 410 (Another partner for ARF 1) ZNF410 APA1 Homo sapiens (Human) negative regulation of gene expression [GO:0010629]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] chromosome [GO:0005694]; nucleus [GO:0005634] DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription coregulator activity [GO:0003712]; transcription regulator activator activity [GO:0140537] 0.91226 -0.75094 DSGPLPQVEKK 0 0 0 0 0 0 0 0 11.598 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86VM9 ZCH18_HUMAN Zinc finger CCCH domain-containing protein 18 (Nuclear protein NHN1) ZC3H18 NHN1 Homo sapiens (Human) RNA destabilization [GO:0050779] nuclear speck [GO:0016607]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904] metal ion binding [GO:0046872]; mRNA cap binding complex binding [GO:0140262]; protein-macromolecule adaptor activity [GO:0030674]; RNA binding [GO:0003723] 0.96372 -2.2389 GEGTPREEGK 0 0 0 0 0 0 0 0 0 11.0804 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86VN1 VPS36_HUMAN Vacuolar protein-sorting-associated protein 36 (ELL-associated protein of 45 kDa) (ESCRT-II complex subunit VPS36) VPS36 C13orf9 EAP45 CGI-145 Homo sapiens (Human) macroautophagy [GO:0016236]; membrane fission [GO:0090148]; multivesicular body assembly [GO:0036258]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328] cytosol [GO:0005829]; endosome [GO:0005768]; ESCRT II complex [GO:0000814]; extracellular exosome [GO:0070062]; late endosome membrane [GO:0031902]; lysosome [GO:0005764]; nucleus [GO:0005634] phosphatidylinositol-3-phosphate binding [GO:0032266]; ubiquitin binding [GO:0043130] 0.83484 0.19171 EPGPFQSSKNSYIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.41382 0 0 0 0 0 0 9.56894 0 0 0 0 10.719 Q86VP1 TAXB1_HUMAN Tax1-binding protein 1 (TRAF6-binding protein) TAX1BP1 T6BP PRO0105 Homo sapiens (Human) apoptotic process [GO:0006915]; autophagy [GO:0006914]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of NF-kappaB transcription factor activity [GO:0032088] autophagosome [GO:0005776]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; phagophore assembly site [GO:0000407] kinase binding [GO:0019900]; metal ion binding [GO:0046872] 0.86647 0.074596 ETELDSLKDKLK 0 0 0 0 0 11.0464 0 0 0 0 0 0 0 9.16664 9.71196 0 0 9.63092 0 0 8.68755 0 0 0 0 0 0 Q86VP3 PACS2_HUMAN Phosphofurin acidic cluster sorting protein 2 (PACS-2) (PACS1-like protein) PACS2 KIAA0602 PACS1L Homo sapiens (Human) apoptotic process [GO:0006915]; autophagosome assembly [GO:0000045]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; mitochondrion-endoplasmic reticulum membrane tethering [GO:1990456]; protein localization to phagophore assembly site [GO:0034497]; protein localization to plasma membrane [GO:0072659] endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739] transmembrane transporter binding [GO:0044325] 0.95161 -1.4234 LICTARQQQNMLR 0 0 0 0 0 0 12.3 10.5133 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.13817 0 0 0 Q86VP6 CAND1_HUMAN Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (TBP-interacting protein of 120 kDa A) (TBP-interacting protein 120A) (p120 CAND1) CAND1 KIAA0829 TIP120 TIP120A Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of catalytic activity [GO:0043086]; positive regulation of RNA polymerase II transcription preinitiation complex assembly [GO:0045899]; protein ubiquitination [GO:0016567]; SCF complex assembly [GO:0010265] cullin-RING ubiquitin ligase complex [GO:0031461]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; ubiquitin ligase complex [GO:0000151] TBP-class protein binding [GO:0017025] 0 9.8329 ALHKQMK 0 0 11.2556 0 0 0 0 0 0 0 0 0 0 0 0 10.2132 0 0 0 9.94481 0 0 0 0 10.3401 12.0611 12.3634 Q86VQ0 LCA5_HUMAN Lebercilin (Leber congenital amaurosis 5 protein) LCA5 C6orf152 Homo sapiens (Human) intraciliary transport [GO:0042073]; photoreceptor cell maintenance [GO:0045494]; protein transport [GO:0015031] axoneme [GO:0005930]; ciliary basal body [GO:0036064]; cilium [GO:0005929]; photoreceptor connecting cilium [GO:0032391] protein-containing complex binding [GO:0044877] 0.96907 -4.1824 EEKPEWETGR 9.75694 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.50791 12.6002 0 0 0 0 0 0 0 0 0 9.59046 Q86VQ3 TXND2_HUMAN Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) TXNDC2 SPTRX SPTRX1 Homo sapiens (Human) cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737] thioredoxin-disulfide reductase activity [GO:0004791] 0.9255 -0.98318 EEKVDELCGALKEK 0 0 0 0 11.2132 0 0 0 0 0 0 0 9.29896 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86VQ6 TRXR3_HUMAN Thioredoxin reductase 3 (EC 1.8.1.9) (Thioredoxin and glutathione reductase) (Thioredoxin reductase TR2) TXNRD3 TGR TRXR3 Homo sapiens (Human) cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] flavin adenine dinucleotide binding [GO:0050660]; thioredoxin-disulfide reductase activity [GO:0004791] 0.88405 -0.29884 ELFSSLGVECNVLELDQVDDGAR 0 9.80386 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.35837 0 0 0 0 0 Q86VR7 VS10L_HUMAN V-set and immunoglobulin domain-containing protein 10-like (VSIG10-like protein) VSIG10L Homo sapiens (Human) membrane [GO:0016020]; nucleoplasm [GO:0005654] 0.96322 -2.1897 APETEEGAAELRLR 0 0 8.61062 0 0 0 0 0 0 0 10.2875 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86VR8 FJX1_HUMAN Four-jointed box protein 1 (Four-jointed protein homolog) FJX1 Homo sapiens (Human) cell-cell signaling [GO:0007267]; retina layer formation [GO:0010842] extracellular space [GO:0005615] 0.63238 0.39808 GQDAAAR 0 0 0 0 0 0 0 0 0 0 0 11.0808 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86VS3 IQCH_HUMAN IQ domain-containing protein H (Testis development protein NYD-SP5) IQCH Homo sapiens (Human) 0.89203 -0.51021 AAPLHSFDEARK 0 0 0 0 0 0 0 0 0 15.4002 15.3902 0 0 0 12.8713 12.8751 12.8605 0 12.1494 12.6557 0 10.7122 0 0 0 0 0 Q86VS8 HOOK3_HUMAN Protein Hook homolog 3 (h-hook3) (hHK3) HOOK3 Homo sapiens (Human) cytoplasmic microtubule organization [GO:0031122]; cytoskeleton-dependent intracellular transport [GO:0030705]; early endosome to late endosome transport [GO:0045022]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; Golgi localization [GO:0051645]; interkinetic nuclear migration [GO:0022027]; lysosome organization [GO:0007040]; microtubule anchoring at centrosome [GO:0034454]; negative regulation of neurogenesis [GO:0050768]; neuronal stem cell population maintenance [GO:0097150]; protein localization to centrosome [GO:0071539]; protein localization to perinuclear region of cytoplasm [GO:1905719]; protein transport [GO:0015031] centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cis-Golgi network [GO:0005801]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; FHF complex [GO:0070695]; microtubule [GO:0005874]; pericentriolar material [GO:0000242] dynactin binding [GO:0034452]; dynein intermediate chain binding [GO:0045505]; dynein light chain binding [GO:0045503]; dynein light intermediate chain binding [GO:0051959]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017] 0.96731 -2.9761 ANAARSQLETYKR 0 10.5167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8108 9.4565 11.3114 11.5225 0 0 0 0 0 Q86VW0 SESD1_HUMAN SEC14 domain and spectrin repeat-containing protein 1 (Huntingtin-interacting protein-like protein) (Protein Solo) SESTD1 SOLO Homo sapiens (Human) negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1904878] intermediate filament cytoskeleton [GO:0045111] "phosphatidic acid binding [GO:0070300]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]" 0.91448 -0.78455 KVTHFCFWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.17562 0 0 0 0 0 Q86VW1 S22AG_HUMAN Solute carrier family 22 member 16 (Carnitine transporter 2) (CT2) (Fly-like putative transporter 2) (FLIPT2) (Flipt 2) (Organic cation transporter OKB1) (Organic cation/carnitine transporter 6) SLC22A16 OCT6 Homo sapiens (Human) acid secretion [GO:0046717]; carnitine transport [GO:0015879]; cell differentiation [GO:0030154]; flagellated sperm motility [GO:0030317]; monoatomic ion transport [GO:0006811]; organic cation transport [GO:0015695]; single fertilization [GO:0007338]; spermatogenesis [GO:0007283] cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886] amine transmembrane transporter activity [GO:0005275]; carnitine transmembrane transporter activity [GO:0015226]; organic cation transmembrane transporter activity [GO:0015101] 0.94335 -1.338 IVDIMAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7985 12.4645 0 0 0 0 0 0 0 10.4465 0 0 Q86VW2 ARHGP_HUMAN Rho guanine nucleotide exchange factor 25 (Guanine nucleotide exchange factor GEFT) (Rac/Cdc42/Rho exchange factor GEFT) (RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT) (p63RhoGEF) ARHGEF25 GEFT Homo sapiens (Human) axon guidance [GO:0007411]; regulation of small GTPase mediated signal transduction [GO:0051056] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; myofibril [GO:0030016]; plasma membrane [GO:0005886]; sarcomere [GO:0030017] guanyl-nucleotide exchange factor activity [GO:0005085] 0.96884 -3.872 DPDWLAQLFIK 0 0 0 0 0 0 0 10.5346 0 0 0 0 9.92655 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86VY9 T200A_HUMAN Transmembrane protein 200A TMEM200A KIAA1913 HBE61 Homo sapiens (Human) membrane [GO:0016020] 0.92248 -1.0841 LENKEDPMDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.06 0 0 0 Q86VZ1 P2RY8_HUMAN P2Y purinoceptor 8 (P2Y8) P2RY8 Homo sapiens (Human) positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of Rho protein signal transduction [GO:0035025] plasma membrane [GO:0005886] G protein-coupled purinergic nucleotide receptor activity [GO:0045028]; G protein-coupled receptor activity [GO:0004930] 0.92932 -1.2303 TEEAHGREQRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.7269 0 0 0 0 0 0 Q86VZ5 SMS1_HUMAN Phosphatidylcholine:ceramide cholinephosphotransferase 1 (EC 2.7.8.27) (Medulla oblongata-derived protein) (Protein Mob) (Sphingomyelin synthase 1) (Transmembrane protein 23) SGMS1 MOB SMS1 TMEM23 Homo sapiens (Human) apoptotic process [GO:0006915]; ceramide biosynthetic process [GO:0046513]; phosphorylation [GO:0016310]; regulation of intrinsic apoptotic signaling pathway [GO:2001242]; sphingolipid biosynthetic process [GO:0030148]; sphingomyelin biosynthetic process [GO:0006686] endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886] ceramide cholinephosphotransferase activity [GO:0047493]; ceramide phosphoethanolamine synthase activity [GO:0002950]; kinase activity [GO:0016301]; sphingomyelin synthase activity [GO:0033188] 0.42827 0.66263 EVVYWSPK 12.2096 0 0 0 0 0 0 0 0 0 0 10.2784 0 0 12.6178 0 0 0 0 10.3416 10.2071 9.64324 10.0312 0 0 0 0 Q86W11 ZSC30_HUMAN Zinc finger and SCAN domain-containing protein 30 (ZNF-WYM) (Zinc finger protein 397 opposite strand) (Zinc finger protein 397OS) ZSCAN30 ZNF397OS Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.9618 -2.0417 GNAAGNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2561 11.428 0 0 0 0 0 0 8.43079 0 0 0 Q86W26 NAL10_HUMAN "NACHT, LRR and PYD domains-containing protein 10 (Nucleotide-binding oligomerization domain protein 8)" NLRP10 NALP10 NOD8 PYNOD Homo sapiens (Human) adaptive immune response [GO:0002250]; defense response to fungus [GO:0050832]; defense response to Gram-negative bacterium [GO:0050829]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 alpha production [GO:0032730]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of T-helper 1 type immune response [GO:0002827]; positive regulation of T-helper 17 type immune response [GO:2000318] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of plasma membrane [GO:0019897]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; GTPase activity [GO:0003924] 0.95921 -1.8277 EASTGKGRGTEETPK 0 0 0 0 0 0 0 9.22195 0 0 8.10743 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6287 Q86W28 NALP8_HUMAN "NACHT, LRR and PYD domains-containing protein 8 (Nucleotide-binding oligomerization domain protein 16) (PYRIN and NACHT-containing protein 4)" NLRP8 NALP8 NOD16 PAN4 Homo sapiens (Human) regulation of inflammatory response [GO:0050727] cytoplasm [GO:0005737] ATP binding [GO:0005524] 0.9669 -2.3178 RPQGRQPK 0 0 10.7456 8.00489 0 0 0 0 0 0 10.4324 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86W33 TPRA1_HUMAN Transmembrane protein adipocyte-associated 1 (Integral membrane protein GPR175) (Transmembrane protein 227) TPRA1 GPR175 TMEM227 PP6566 Homo sapiens (Human) aging [GO:0007568]; embryonic cleavage [GO:0040016]; G protein-coupled receptor signaling pathway [GO:0007186]; lipid metabolic process [GO:0006629]; negative regulation of mitotic cell cycle phase transition [GO:1901991] membrane [GO:0016020]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930] 0.83315 0.19947 ILWEITR 0 0 0 0 0 0 0 9.23707 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86W42 THOC6_HUMAN THO complex subunit 6 homolog (Functional spliceosome-associated protein 35) (fSAP35) (WD repeat-containing protein 58) THOC6 WDR58 PSEC0006 Homo sapiens (Human) apoptotic process [GO:0006915]; central nervous system development [GO:0007417]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; negative regulation of apoptotic process [GO:0043066]; RNA splicing [GO:0008380]; viral mRNA export from host cell nucleus [GO:0046784] nuclear body [GO:0016604]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; THO complex [GO:0000347]; THO complex part of transcription export complex [GO:0000445]; transcription export complex [GO:0000346] RNA binding [GO:0003723] 0.0096154 1.7726 VDVFTNLGYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8583 0 Q86W54 SPA24_HUMAN Spermatogenesis-associated protein 24 (Testis protein T6441 homolog) SPATA24 Homo sapiens (Human) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; cytosol [GO:0005829]; male germ cell nucleus [GO:0001673]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; identical protein binding [GO:0042802] 0.96821 -3.6135 ENEIKELQQVISQQK 0 0 0 0 0 0 0 0 0 0 9.71442 0 0 0 0 0 0 0 9.3025 0 0 0 0 0 0 0 0 Q86W56 PARG_HUMAN Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143) PARG Homo sapiens (Human) "ATP generation from poly-ADP-D-ribose [GO:1990966]; base-excision repair, gap-filling [GO:0006287]; carbohydrate metabolic process [GO:0005975]; nucleotide-sugar metabolic process [GO:0009225]; regulation of DNA repair [GO:0006282]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] poly(ADP-ribose) glycohydrolase activity [GO:0004649] 0.89483 -0.51901 DNFYQHNVEK 9.21515 0 0 0 0 0 0 0 0 0 0 0 0 9.55921 0 0 0 0 0 0 0 0 0 0 10.019 0 0 Q86W92 LIPB1_HUMAN Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2) PPFIBP1 KIAA1230 Homo sapiens (Human) cell adhesion [GO:0007155]; neuromuscular junction development [GO:0007528] cytosol [GO:0005829]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; presynaptic active zone [GO:0048786] cadherin binding [GO:0045296] 0.96945 -3.4917 GGTRATAGPR 9.50434 0 0 0 10.2333 0 0 0 0 0 9.50118 8.92294 0 10.6997 0 0 0 0 0 0 8.535 0 0 0 0 0 0 Q86WA8 LONP2_HUMAN "Lon protease homolog 2, peroxisomal (EC 3.4.21.53) (Lon protease-like protein 2) (Lon protease 2) (Peroxisomal Lon protease) (pLon)" LONP2 LONP Homo sapiens (Human) peroxisome organization [GO:0007031]; protein import into peroxisome matrix [GO:0016558]; protein processing [GO:0016485]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein targeting to peroxisome [GO:0006625]; regulation of fatty acid beta-oxidation [GO:0031998]; response to organic cyclic compound [GO:0014070] cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent peptidase activity [GO:0004176]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252] 0.96942 -3.5885 AVAVKVAEGQHK 0 10.5203 10.1248 0 8.89394 0 0 0 0 0 0 0 0 0 0 11.1405 0 0 0 0 0 0 0 0 0 0 0 Q86WA9 S2611_HUMAN Sodium-independent sulfate anion transporter (Solute carrier family 26 member 11) SLC26A11 Homo sapiens (Human) monoatomic ion transport [GO:0006811]; sulfate transport [GO:0008272] endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] monoatomic anion transmembrane transporter activity [GO:0008509]; secondary active sulfate transmembrane transporter activity [GO:0008271]; sulfate transmembrane transporter activity [GO:0015116] 0.77153 0.27471 PSSVTALGQAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.15203 0 10.3868 0 0 0 Q86WD7 SPA9_HUMAN Serpin A9 (Centerin) (Germinal center B-cell-expressed transcript 1 protein) SERPINA9 GCET1 SERPINA11 UNQ692/PRO1337 Homo sapiens (Human) negative regulation of endopeptidase activity [GO:0010951] cytoplasm [GO:0005737]; extracellular space [GO:0005615]; membrane [GO:0016020] serine-type endopeptidase inhibitor activity [GO:0004867] 0.92168 -1.0877 MGSALFVK 9.58459 0 0 0 0 0 0 0 0 0 0 9.03461 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86WG5 MTMRD_HUMAN Myotubularin-related protein 13 (Inactive phosphatidylinositol 3-phosphatase 13) (SET-binding factor 2) SBF2 CMT4B2 KIAA1766 MTMR13 Homo sapiens (Human) autophagy [GO:0006914]; myelination [GO:0042552] axon [GO:0030424]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; vacuolar membrane [GO:0005774] guanyl-nucleotide exchange factor activity [GO:0005085]; identical protein binding [GO:0042802]; phosphatase binding [GO:0019902]; phosphatase regulator activity [GO:0019208]; phosphatidylinositol binding [GO:0035091] 0.96205 -2.553 ELAEQLFK 0 0 8.89915 0 0 0 0 0 0 0 11.7503 9.10431 8.96913 0 0 0 0 10.842 9.37239 0 0 0 0 0 0 0 0 Q86WH2 RASF3_HUMAN Ras association domain-containing protein 3 RASSF3 Homo sapiens (Human) signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; microtubule [GO:0005874]; plasma membrane [GO:0005886] identical protein binding [GO:0042802] 0.69549 0.3811 FLVTESPAK 0 0 0 0 0 0 0 10.6037 10.5284 0 10.3388 0 10.4728 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86WI1 PKHL1_HUMAN Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) PKHD1L1 Homo sapiens (Human) immune response [GO:0006955]; sensory perception of sound [GO:0007605] cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; stereocilium coat [GO:0120234]; stereocilium tip [GO:0032426] signaling receptor activity [GO:0038023] 0.96351 -2.2321 AGFRWEHEMVMIDVDGSLTGHK 0 0 0 0 0 0 0 0 0 0 0 9.69464 0 0 0 0 9.64346 9.03202 0 9.65071 10.5071 0 0 0 0 11.8976 0 Q86WJ1 CHD1L_HUMAN Chromodomain-helicase-DNA-binding protein 1-like (EC 3.6.4.-) (Amplified in liver cancer protein 1) CHD1L ALC1 Homo sapiens (Human) chromatin remodeling [GO:0006338]; DNA damage response [GO:0006974]; DNA repair [GO:0006281] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent chromatin remodeler activity [GO:0140658]; DNA helicase activity [GO:0003678]; histone reader activity [GO:0140566]; nucleosome binding [GO:0031491]; nucleotide binding [GO:0000166]; poly-ADP-D-ribose modification-dependent protein binding [GO:0160004] 0.97006 -5.1399 DYSKEPSK 0 0 0 0 0 0 0 0 0 0 12.2931 0 0 0 0 0 0 0 10.1127 0 0 0 0 0 0 0 0 Q86WK6 AMGO1_HUMAN Amphoterin-induced protein 1 (AMIGO-1) (Alivin-2) AMIGO1 ALI2 AMIGO KIAA1163 Homo sapiens (Human) axonal fasciculation [GO:0007413]; axonogenesis [GO:0007409]; brain development [GO:0007420]; cellular response to L-glutamate [GO:1905232]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; myelination [GO:0042552]; positive regulation of axonogenesis [GO:0050772]; positive regulation of neuron projection development [GO:0010976]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of synapse assembly [GO:0051965]; positive regulation of voltage-gated potassium channel activity [GO:1903818] dendrite [GO:0030425]; neuronal cell body membrane [GO:0032809]; pericellular basket [GO:1990030]; perikaryon [GO:0043204]; voltage-gated potassium channel complex [GO:0008076] potassium channel regulator activity [GO:0015459] 0.87086 0.03407 YLDLSSNQLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3968 0 0 0 0 Q86WK7 AMGO3_HUMAN Amphoterin-induced protein 3 (AMIGO-3) (Alivin-3) AMIGO3 ALI3 KIAA1851 UNQ6084/PRO20089 Homo sapiens (Human) brain development [GO:0007420]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of neuron projection development [GO:0010977]; positive regulation of synapse assembly [GO:0051965] membrane [GO:0016020] protein-containing complex binding [GO:0044877] 0.88968 -0.47086 ALGRHDLDGLGALEK 14.4149 0 0 13.3424 0 0 0 12.4839 12.6347 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86WN1 FCSD1_HUMAN F-BAR and double SH3 domains protein 1 (Protein nervous wreck 2) (NWK2) FCHSD1 UNQ737/PRO1431 Homo sapiens (Human) membrane organization [GO:0061024]; neuromuscular synaptic transmission [GO:0007274]; positive regulation of actin filament polymerization [GO:0030838]; regulation of actin filament polymerization [GO:0030833] cell projection [GO:0042995]; cuticular plate [GO:0032437]; neuromuscular junction [GO:0031594]; perikaryon [GO:0043204]; recycling endosome [GO:0055037] lipid binding [GO:0008289] 0.91499 -0.78012 AAIEREYGQALQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.24693 Q86WN2 IFNE_HUMAN Interferon epsilon (IFN-epsilon) (Interferon epsilon-1) IFNE IFNE1 UNQ360/PRO655 Homo sapiens (Human) adaptive immune response [GO:0002250]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; cellular response to virus [GO:0098586]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; natural killer cell activation involved in immune response [GO:0002323]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon-mediated signaling pathway [GO:0060337] extracellular space [GO:0005615] cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132] 0.91583 -0.77616 CLFFVFSLTEK 11.39 11.357 11.3112 0 0 0 11.7268 11.7249 0 0 0 0 0 0 0 0 11.5961 0 0 0 0 0 0 0 0 12.3351 0 Q86WP2 GPBP1_HUMAN Vasculin (GC-rich promoter-binding protein 1) (Vascular wall-linked protein) GPBP1 GPBP SSH6 Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355] cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; plasma membrane [GO:0005886] DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; RNA binding [GO:0003723] 0.56071 0.51644 ECNRSNSSSPVDK 0 0 0 0 0 0 0 0 0 0 12.7421 0 0 0 0 0 0 8.52482 0 0 0 0 0 0 0 0 0 Q86WR0 CCD25_HUMAN Coiled-coil domain-containing protein 25 CCDC25 Homo sapiens (Human) positive regulation of cell motility [GO:2000147] endomembrane system [GO:0012505]; plasma membrane [GO:0005886] DNA binding [GO:0003677] 0.050847 1.4236 LSSAHVYLR 9.05978 0 0 0 0 0 0 0 0 0 0 16.2196 0 13.9103 13.0919 0 0 0 0 0 0 0 0 0 0 0 0 Q86WR6 CHCT1_HUMAN CHD1 helical C-terminal domain containing protein 1 CHCT1 C17orf64 Homo sapiens (Human) cytoplasm [GO:0005737] 0.88423 -0.29875 DSLRELSQKPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.6606 0 0 0 0 0 0 Q86WS4 CL040_HUMAN Uncharacterized protein C12orf40 C12orf40 Homo sapiens (Human) 0.92692 -1.2059 DIKMPLRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.39695 0 Q86WT1 IT70A_HUMAN Intraflagellar transport protein 70A (Tetratricopeptide repeat protein 30A) (TPR repeat protein 30A) IFT70A TTC30A Homo sapiens (Human) intraciliary transport [GO:0042073] axonemal microtubule [GO:0005879]; intraciliary transport particle B [GO:0030992] intraciliary transport particle B binding [GO:0120170] 0.88582 -0.33698 KAVNEYDETMEKYIPVLMAQAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1561 0 0 0 Q86WT6 TRI69_HUMAN E3 ubiquitin-protein ligase TRIM69 (EC 2.3.2.27) (RFP-like domain-containing protein trimless) (RING finger protein 36) (RING-type E3 ubiquitin transferase TRIM69) (Tripartite motif-containing protein 69) TRIM69 RNF36 HSD-34 HSD34 Homo sapiens (Human) apoptotic process [GO:0006915]; protein ubiquitination [GO:0016567] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleus [GO:0005634] identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.8299 0.20925 WYWEVEVAK 0 0 0 0 0 0 0 0 0 0 10.148 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86WU2 LDHD_HUMAN "Probable D-lactate dehydrogenase, mitochondrial (DLD) (Lactate dehydrogenase D) (EC 1.1.2.4)" LDHD Homo sapiens (Human) lactate catabolic process [GO:1903457] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] D-lactate dehydrogenase (cytochrome) activity [GO:0004458]; D-lactate dehydrogenase activity [GO:0008720]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660] 0.9279 -1.2237 AKGELCRDFVEALK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7793 0 0 0 0 0 0 10.5111 0 0 0 0 0 0 Q86WV1 SKAP1_HUMAN Src kinase-associated phosphoprotein 1 (Src family-associated phosphoprotein 1) (Src kinase-associated phosphoprotein of 55 kDa) (SKAP-55) (pp55) SKAP1 SCAP1 SKAP55 Homo sapiens (Human) adaptive immune response [GO:0002250]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of integrin activation [GO:0033625]; positive regulation of leukocyte cell-cell adhesion [GO:1903039]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; T cell receptor signaling pathway [GO:0050852] cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; immunological synapse [GO:0001772]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; T cell receptor complex [GO:0042101] protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124] 0.51689 0.59215 DWVDQISFLLK 10.9218 11.0353 11.0016 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86WV6 STING_HUMAN Stimulator of interferon genes protein (hSTING) (Endoplasmic reticulum interferon stimulator) (ERIS) (Mediator of IRF3 activation) (hMITA) (Transmembrane protein 173) STING1 ERIS MITA STING TMEM173 Homo sapiens (Human) activation of innate immune response [GO:0002218]; antiviral innate immune response [GO:0140374]; autophagosome assembly [GO:0000045]; cellular response to exogenous dsRNA [GO:0071360]; cellular response to interferon-beta [GO:0035458]; cellular response to organic cyclic compound [GO:0071407]; cytosolic pattern recognition receptor signaling pathway [GO:0002753]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of macroautophagy [GO:0016239]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein complex oligomerization [GO:0051259]; regulation of inflammatory response [GO:0050727]; reticulophagy [GO:0061709] autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endosome [GO:0005768]; Golgi membrane [GO:0000139]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; serine/threonine protein kinase complex [GO:1902554]; STING complex [GO:1990231] "2',3'-cyclic GMP-AMP binding [GO:0061507]; cyclic-di-GMP binding [GO:0035438]; identical protein binding [GO:0042802]; molecular function activator activity [GO:0140677]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activator activity [GO:0043539]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; signaling adaptor activity [GO:0035591]; ubiquitin protein ligase binding [GO:0031625]" 0.9528 -1.4696 TVRACLGCPLR 0 0 0 0 0 0 0 0 0 9.50641 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86WX3 AROS_HUMAN Active regulator of SIRT1 (40S ribosomal protein S19-binding protein 1) (RPS19-binding protein 1) (S19BP) RPS19BP1 AROS Homo sapiens (Human) ribosomal small subunit biogenesis [GO:0042274] cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040] enzyme binding [GO:0019899]; RNA binding [GO:0003723] 0.90217 -0.70208 SALDEYRK 0 0 0 0 0 0 0 0 0 10.5541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86WZ0 HEAT4_HUMAN HEAT repeat-containing protein 4 HEATR4 Homo sapiens (Human) oxidoreductase activity [GO:0016491] 0.92327 -1.0776 AWEATVLEK 10.1294 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86WZ6 ZN227_HUMAN Zinc finger protein 227 ZNF227 Homo sapiens (Human) nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.90728 -0.73347 CEECGKGFGRSLNLR 9.5273 0 0 9.14366 8.7184 10.4114 0 0 0 0 0 8.83684 0 0 0 0 0 0 0 0 0 9.4274 0 0 0 0 0 Q86X02 CDR2L_HUMAN Cerebellar degeneration-related protein 2-like (Paraneoplastic 62 kDa antigen) CDR2L HUMPPA Homo sapiens (Human) Golgi to secretory granule transport [GO:0055107]; vesicle transport along microtubule [GO:0047496] cytoplasm [GO:0005737] identical protein binding [GO:0042802] 0.87127 0.064272 EYTAVLQEYSELER 9.41306 0 9.28778 0 0 0 0 0 8.79435 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86X10 RLGPB_HUMAN Ral GTPase-activating protein subunit beta (p170) RALGAPB KIAA1219 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056] GTPase activator activity [GO:0005096]; protein heterodimerization activity [GO:0046982] 0.96862 -3.348 LESDSYSPPHVRR 0 0 0 0 0 0 0 0 0 0 9.97757 0 0 0 0 0 0 0 0 9.49506 0 9.50339 0 0 0 0 0 Q86X19 TMM17_HUMAN Transmembrane protein 17 TMEM17 Homo sapiens (Human) cilium assembly [GO:0060271]; non-motile cilium assembly [GO:1905515]; smoothened signaling pathway [GO:0007224] ciliary membrane [GO:0060170]; ciliary transition zone [GO:0035869]; MKS complex [GO:0036038] 0.91322 -0.78702 AVFSDSNR 0 9.72514 0 0 0 0 0 0 0 0 10.5605 0 0 0 0 0 0 0 0 9.26545 0 0 0 0 0 0 0 Q86X24 HORM1_HUMAN HORMA domain-containing protein 1 (Cancer/testis antigen 46) (CT46) (Newborn ovary HORMA protein) HORMAD1 NOHMA Homo sapiens (Human) blastocyst development [GO:0001824]; meiotic cell cycle [GO:0051321]; meiotic DNA double-strand break formation [GO:0042138]; meiotic recombination checkpoint signaling [GO:0051598]; meiotic sister chromatid cohesion [GO:0051177]; oogenesis [GO:0048477]; regulation of homologous chromosome segregation [GO:0060629]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130] chromosome [GO:0005694]; nucleus [GO:0005634]; synaptonemal complex [GO:0000795] 0.84183 0.14731 IVLHHFDSSSQESVPK 0 0 0 0 0 0 0 0 0 0 0 9.79666 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86X29 LSR_HUMAN Lipolysis-stimulated lipoprotein receptor (Angulin-1) LSR ILDR3 LISCH Homo sapiens (Human) epithelial structure maintenance [GO:0010669]; establishment of blood-brain barrier [GO:0060856]; establishment of skin barrier [GO:0061436]; liver development [GO:0001889]; maintenance of blood-brain barrier [GO:0035633]; protein localization to tricellular tight junction [GO:0061833]; tricellular tight junction assembly [GO:1904274] bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; chylomicron [GO:0042627]; extracellular exosome [GO:0070062]; low-density lipoprotein particle [GO:0034362]; plasma membrane [GO:0005886]; tight junction [GO:0070160]; tricellular tight junction [GO:0061689]; very-low-density lipoprotein particle [GO:0034361] 0.0098765 1.8278 AATSGVPSIYAPSTYAHLSPAK 0 0 0 0 0 0 0 0 0 15.4002 0 0 0 0 0 0 0 0 0 0 0 0 0 8.50458 0 10.2855 0 Q86X40 LRC28_HUMAN Leucine-rich repeat-containing protein 28 LRRC28 UNQ436/PRO867 Homo sapiens (Human) 0.84495 0.15301 NLFLNYR 0 0 0 0 9.4633 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86X45 DAA11_HUMAN Dynein axonemal assembly factor 11 (DNAAF11) (Leucine-rich repeat-containing protein 6) (Leucine-rich testis-specific protein) (Protein tilB homolog) (Testis-specific leucine-rich repeat protein) DNAAF11 LRRC6 LRTP TSLRP Homo sapiens (Human) axonemal dynein complex assembly [GO:0070286]; cerebrospinal fluid circulation [GO:0090660]; cilium movement [GO:0003341]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; inner dynein arm assembly [GO:0036159]; male gonad development [GO:0008584]; motile cilium assembly [GO:0044458]; outer dynein arm assembly [GO:0036158]; protein localization to cilium [GO:0061512]; protein localization to motile cilium [GO:0120229]; regulation of protein binding [GO:0043393]; reproductive system development [GO:0061458] apical cytoplasm [GO:0090651]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dynein axonemal particle [GO:0120293]; extracellular region [GO:0005576]; motile cilium [GO:0031514] 0.70533 0.37 SREQTNTRSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.13684 0 0 0 0 0 0 0 0 0 0 0 0 Q86X51 EZHIP_HUMAN EZH inhibitory protein EZHIP CXorf67 Homo sapiens (Human) chromatin organization [GO:0006325]; epigenetic regulation of gene expression [GO:0040029]; negative regulation of histone H3-K27 trimethylation [GO:1902465] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] histone methyltransferase inhibitor activity [GO:0180000] 0.86089 0.092271 ATQSDMEKEQK 0 14.6681 0 11.187 0 0 15.064 15.1282 0 0 0 14.2761 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86X52 CHSS1_HUMAN Chondroitin sulfate synthase 1 (EC 2.4.1.175) (EC 2.4.1.226) (Chondroitin glucuronyltransferase 1) (Chondroitin synthase 1) (ChSy-1) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1) (N-acetylgalactosaminyltransferase 1) CHSY1 CHSY CSS1 KIAA0990 UNQ756/PRO1487 Homo sapiens (Human) bone morphogenesis [GO:0060349]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; negative regulation of ossification [GO:0030279]; positive regulation of smoothened signaling pathway [GO:0045880]; proximal/distal pattern formation [GO:0009954]; response to nutrient levels [GO:0031667]; sulfation [GO:0051923] extracellular region [GO:0005576]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; membrane [GO:0016020] glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity [GO:0047238]; metal ion binding [GO:0046872]; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity [GO:0050510] 0.96926 -3.5935 AVAAYRTWSK 10.7629 10.2192 0 0 0 0 11.9103 9.83769 0 0 13.9003 9.11863 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86X53 ERIC1_HUMAN Glutamate-rich protein 1 ERICH1 HSPC319 Homo sapiens (Human) 0.95463 -1.5017 QQSLLQEKSQR 0 0 0 0 0 0 0 10.721 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86X95 CIR1_HUMAN Corepressor interacting with RBPJ 1 (CBF1-interacting corepressor) (Recepin) CIR1 CIR Homo sapiens (Human) in utero embryonic development [GO:0001701]; mRNA processing [GO:0006397]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; RNA splicing [GO:0008380] cytoplasm [GO:0005737]; microtubule organizing center [GO:0005815]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] histone deacetylase binding [GO:0042826]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; transcription corepressor activity [GO:0003714] 0.96187 -2.0704 KLHEELSSSHHNREK 10.9369 0 0 0 0 0 0 0 0 0 0 0 11.8375 0 0 0 0 0 0 0 0 10.0639 0 0 0 0 0 Q86XA9 HTR5A_HUMAN HEAT repeat-containing protein 5A HEATR5A C14orf125 KIAA1316 Homo sapiens (Human) "endocytosis [GO:0006897]; protein localization [GO:0008104]; retrograde transport, endosome to Golgi [GO:0042147]" cytosol [GO:0005829]; endocytic vesicle [GO:0030139] 0.94608 -1.3437 AEFIFEWLR 0 0 0 0 0 0 0 10.2819 0 0 0 0 0 0 0 0 0 0 0 8.48692 0 0 0 0 0 0 8.9695 Q86XD8 ZFAN4_HUMAN AN1-type zinc finger protein 4 (AN1-type zinc finger and ubiquitin domain-containing protein-like 1) ZFAND4 ANUBL1 Homo sapiens (Human) zinc ion binding [GO:0008270] 0.95102 -1.4202 MAEYLDSSR 0 0 11.6149 0 0 0 0 11.7889 0 0 0 11.8505 0 0 0 0 10.0824 9.51546 0 0 0 0 0 0 0 0 10.5784 Q86XE3 MICU3_HUMAN "Calcium uptake protein 3, mitochondrial (EF-hand domain-containing family member A2)" MICU3 EFHA2 Homo sapiens (Human) calcium import into the mitochondrion [GO:0036444]; mitochondrial calcium ion homeostasis [GO:0051560] mitochondrial inner membrane [GO:0005743]; uniplex complex [GO:1990246] calcium ion binding [GO:0005509] 0.96302 -2.1644 DDQLSYK 10.7204 10.5588 10.73 0 0 0 0 10.8436 10.927 11.0851 0 10.8755 0 0 0 14.0591 14.0797 14.0592 0 0 0 0 0 0 13.6373 0 0 Q86XE5 HOGA1_HUMAN "4-hydroxy-2-oxoglutarate aldolase, mitochondrial (EC 4.1.3.16) (Dihydrodipicolinate synthase-like) (DHDPS-like protein) (Probable 2-keto-4-hydroxyglutarate aldolase) (Probable KHG-aldolase) (Protein 569272)" HOGA1 C10orf65 DHDPSL Homo sapiens (Human) 4-hydroxyproline catabolic process [GO:0019470]; glyoxylate catabolic process [GO:0009436]; glyoxylate metabolic process [GO:0046487]; N-acetylneuraminate catabolic process [GO:0019262]; oxalate metabolic process [GO:0033609]; pyruvate biosynthetic process [GO:0042866] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] (4S)-4-hydroxy-2-oxoglutarate aldolase activity [GO:0106009]; 4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]; N-acetylneuraminate lyase activity [GO:0008747]; protein homodimerization activity [GO:0042803] 0.90039 -0.69344 LCCTGQWEDAQK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.08042 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86XF0 DYR2_HUMAN "Dihydrofolate reductase 2, mitochondrial (Dihydrofolate reductase, mitochondrial) (EC 1.5.1.3) (Dihydrofolate reductase-like protein 1)" DHFR2 DHFRL1 DHFRP4 Homo sapiens (Human) dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]; thymidine biosynthetic process [GO:0046105] cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] dihydrofolate reductase activity [GO:0004146]; folate reductase activity [GO:0033560]; mRNA binding [GO:0003729]; NADP binding [GO:0050661] 0.95429 -1.5303 YKFEVCEK 0 0 0 0 0 0 0 0 0 0 11.9149 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86XH1 DRC11_HUMAN Dynein regulatory complex protein 11 (IQ and AAA domain-containing protein 1) IQCA1 DRC11 IQCA Homo sapiens (Human) cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; motile cilium [GO:0031514] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; microtubule severing ATPase activity [GO:0008568] 0.96983 -4.1266 DESWNFSQDYDPELIKEEKR 0 9.31594 0 0 0 0 0 0 0 9.45843 0 0 0 0 0 0 0 11.2757 0 0 0 0 0 0 0 0 0 Q86XJ1 GA2L3_HUMAN GAS2-like protein 3 (Growth arrest-specific protein 2-like 3) GAS2L3 Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton organization [GO:0030036]; microtubule cytoskeleton organization [GO:0000226] actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630] actin binding [GO:0003779]; actin filament binding [GO:0051015]; cytoskeletal anchor activity [GO:0008093]; microtubule binding [GO:0008017] 0.95235 -1.4618 CISSPNTPKAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.69572 0 0 0 0 0 Q86XK2 FBX11_HUMAN F-box only protein 11 (Protein arginine N-methyltransferase 9) (Vitiligo-associated protein 1) (VIT-1) FBXO11 FBX11 PRMT9 VIT1 UG063H01 Homo sapiens (Human) negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1904878]; positive regulation of protein catabolic process [GO:0045732]; protein modification process [GO:0036211]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; sensory perception of sound [GO:0007605]; ubiquitin-dependent protein catabolic process [GO:0006511] chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151] protein-arginine N-methyltransferase activity [GO:0016274]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.78612 0.2584 FGGLFLASGVNVTMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.47131 0 0 0 0 0 9.96476 Q86XK3 SFR1_HUMAN Swi5-dependent recombination DNA repair protein 1 homolog (Meiosis protein 5 homolog) SFR1 C10orf78 MEI5 MEIR5 Homo sapiens (Human) cellular response to estrogen stimulus [GO:0071391]; double-strand break repair via homologous recombination [GO:0000724]; positive regulation of DNA-templated transcription [GO:0045893] centrosome [GO:0005813]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Swi5-Sfr1 complex [GO:0032798] nuclear receptor coactivator activity [GO:0030374] 0.8901 -0.50001 FSFNSSYNVVK 0 0 0 8.3319 8.61574 8.69919 0 0 0 11.2523 11.1639 0 0 0 0 0 0 8.82572 0 0 0 10.4909 10.4688 0 0 0 0 Q86XK7 VSIG1_HUMAN V-set and immunoglobulin domain-containing protein 1 (Cell surface A33 antigen) (Glycoprotein A34) VSIG1 GPA34 Homo sapiens (Human) epithelial cell morphogenesis [GO:0003382]; maintenance of gastrointestinal epithelium [GO:0030277] basolateral plasma membrane [GO:0016323] 0.41556 0.68422 EQLSIQWSFFHKK 0 0 0 10.7003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86XL3 ANKL2_HUMAN Ankyrin repeat and LEM domain-containing protein 2 (LEM domain-containing protein 4) ANKLE2 KIAA0692 LEM4 Homo sapiens (Human) cell division [GO:0051301]; central nervous system development [GO:0007417]; mitotic nuclear membrane reassembly [GO:0007084]; negative regulation of apoptotic process [GO:0043066]; negative regulation of phosphorylation [GO:0042326]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of catalytic activity [GO:0050790] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] protein phosphatase 2A binding [GO:0051721]; protein phosphatase regulator activity [GO:0019888] 0.92285 -1.1032 ANSYKNPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6939 0 0 0 0 0 0 0 9.95629 0 0 0 Q86XN6 ZN761_HUMAN Zinc finger protein 761 ZNF761 KIAA2033 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96909 -3.3752 KSYLTCHHR 0 0 0 0 0 0 0 0 11.403 0 0 0 0 0 0 0 9.73178 0 0 0 0 0 0 0 0 0 0 Q86XN7 PRSR1_HUMAN Proline and serine-rich protein 1 PROSER1 C13orf23 KIAA2032 Homo sapiens (Human) 0.8768 0.0021361 AIEYVHGYFSSEQVVDLLR 0 0 0 0 0 10.0164 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86XP0 PA24D_HUMAN Cytosolic phospholipase A2 delta (cPLA2-delta) (EC 3.1.1.4) (Phospholipase A2 group IVD) PLA2G4D Homo sapiens (Human) fatty acid metabolic process [GO:0006631]; glycerophospholipid catabolic process [GO:0046475]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149] cytosol [GO:0005829]; membrane [GO:0016020] calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; calcium-dependent phospholipid binding [GO:0005544]; phospholipase A1 activity [GO:0008970] 0.95537 -1.5576 YAREHLAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7188 Q86XP1 DGKH_HUMAN Diacylglycerol kinase eta (DAG kinase eta) (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) DGKH Homo sapiens (Human) diacylglycerol metabolic process [GO:0046339]; intracellular signal transduction [GO:0035556]; lipid phosphorylation [GO:0046834]; negative regulation of catalytic activity [GO:0043086]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidic acid metabolic process [GO:0046473]; platelet activation [GO:0030168]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; endosome [GO:0005768]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] ATP binding [GO:0005524]; diacylglycerol kinase activity [GO:0004143]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; metal ion binding [GO:0046872]; SAM domain binding [GO:0032093] 0.92604 -1.211 DIFIRHDIR 0 0 0 0 0 0 0 0 0 0 10.844 0 0 0 0 0 0 0 0 0 0 0 0 0 8.92947 0 0 Q86XP3 DDX42_HUMAN ATP-dependent RNA helicase DDX42 (EC 3.6.4.13) (DEAD box protein 42) (RNA helicase-like protein) (RHELP) (RNA helicase-related protein) (RNAHP) (SF3b DEAD box protein) (Splicing factor 3B-associated 125 kDa protein) (SF3b125) DDX42 Homo sapiens (Human) protein localization [GO:0008104]; regulation of apoptotic process [GO:0042981] Cajal body [GO:0015030]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.96331 -2.4396 ELLDLAMQNAWFR 8.02259 11.8147 7.93776 0 0 0 12.3778 0 10.0497 0 0 8.86102 0 0 0 0 0 0 0 8.81618 9.24914 0 0 0 0 0 0 Q86XQ3 CTSR3_HUMAN Cation channel sperm-associated protein 3 (CatSper3) (Ca(v)-like protein) (One-repeat calcium channel-like protein) CATSPER3 Homo sapiens (Human) establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; regulation of monoatomic ion transmembrane transport [GO:0034765]; sodium ion transport [GO:0006814]; sperm capacitation [GO:0048240] acrosomal vesicle [GO:0001669]; CatSper complex [GO:0036128]; endoplasmic reticulum [GO:0005783]; motile cilium [GO:0031514]; plasma membrane [GO:0005886] voltage-gated calcium channel activity [GO:0005245] 0.9408 -1.3297 VIMSRFFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.49185 0 0 0 0 0 0 0 0 0 Q86XR8 CEP57_HUMAN Centrosomal protein of 57 kDa (Cep57) (FGF2-interacting protein) (Testis-specific protein 57) (Translokin) CEP57 KIAA0092 TSP57 Homo sapiens (Human) fibroblast growth factor receptor signaling pathway [GO:0008543]; protein homooligomerization [GO:0051260]; spermatid development [GO:0007286] centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; microtubule [GO:0005874]; nucleus [GO:0005634] fibroblast growth factor binding [GO:0017134]; gamma-tubulin binding [GO:0043015]; microtubule binding [GO:0008017]; protein homodimerization activity [GO:0042803] 0.96546 -2.7106 AIFSALKNLQDK 0 9.96996 9.78591 0 0 0 0 0 0 0 0 0 0 8.97062 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86XS5 ANGL5_HUMAN Angiopoietin-related protein 5 (Angiopoietin-like protein 5) ANGPTL5 UNQ5795/PRO19600 Homo sapiens (Human) collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615] signaling receptor binding [GO:0005102] 0.96737 -3.7504 EDCEESCDVKTK 0 0 0 0 0 0 0 0 0 11.1679 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86XS8 GOLI_HUMAN E3 ubiquitin-protein ligase RNF130 (EC 2.3.2.27) (Goliath homolog) (H-Goliath) (RING finger protein 130) (RING-type E3 ubiquitin transferase RNF130) RNF130 Homo sapiens (Human) apoptotic process [GO:0006915]; programmed cell death [GO:0012501]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737]; membrane [GO:0016020] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.89024 -0.4752 LTRTQAVNR 0 0 10.1731 0 0 0 0 0 0 0 0 0 9.43888 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86XT2 VP37D_HUMAN Vacuolar protein sorting-associated protein 37D (ESCRT-I complex subunit VPS37D) (Williams-Beuren syndrome chromosomal region 24 protein) VPS37D WBSCR24 Homo sapiens (Human) macroautophagy [GO:0016236]; membrane fission [GO:0090148]; multivesicular body assembly [GO:0036258]; protein targeting to membrane [GO:0006612]; protein targeting to vacuole [GO:0006623]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding via host ESCRT complex [GO:0039702] endosome membrane [GO:0010008]; ESCRT I complex [GO:0000813]; extracellular exosome [GO:0070062]; late endosome membrane [GO:0031902] 0.93762 -1.2929 DLLQDEPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.0285 0 0 0 0 0 0 0 0 0 0 0 0 Q86XT4 TRI50_HUMAN E3 ubiquitin-protein ligase TRIM50 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM50) (Tripartite motif-containing protein 50) TRIM50 TRIM50A Homo sapiens (Human) protein ubiquitination [GO:0016567] cytoplasm [GO:0005737]; cytosol [GO:0005829] identical protein binding [GO:0042802]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.88136 -0.027103 IVNESDVFSWVIRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.761 0 0 0 0 0 Q86XU0 ZN677_HUMAN Zinc finger protein 677 ZNF677 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96156 -2.5684 AFTQFANLTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2026 10.1701 0 0 0 0 10.9571 10.7768 Q86XW9 TXND6_HUMAN Thioredoxin domain-containing protein 6 (Thioredoxin-like protein 2) (Txl-2) NME9 TXL2 TXNDC6 Homo sapiens (Human) CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228] cell projection [GO:0042995]; cytoskeleton [GO:0005856]; dynein axonemal particle [GO:0120293] nucleoside diphosphate kinase activity [GO:0004550] 0.56437 0.49746 NNGEDEDMVSSER 0 0 0 0 0 0 0 0 9.25188 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8061 0 0 Q86XX4 FRAS1_HUMAN Extracellular matrix organizing protein FRAS1 (Fraser syndrome 1 protein) FRAS1 KIAA1500 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; protein transport [GO:0015031]; roof of mouth development [GO:0060021]; skin development [GO:0043588] basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; plasma membrane [GO:0005886] extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872] 0.92564 -0.96726 CGEGFYSDHGVCK 0 0 0 0 0 0 0 0 9.55488 0 0 0 0 0 8.53045 9.62207 8.82397 10.9586 0 0 0 0 0 0 0 0 0 Q86XZ4 SPAS2_HUMAN Spermatogenesis-associated serine-rich protein 2 (Serine-rich spermatocytes and round spermatid 59 kDa protein) (p59scr) SPATS2 SCR59 SPATA10 Nbla00526 Homo sapiens (Human) cytoplasm [GO:0005737]; cytosol [GO:0005829] RNA binding [GO:0003723] 0.80883 0.2252 SIDSFGQVSHPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.79225 0 0 0 0 0 Q86Y13 DZIP3_HUMAN E3 ubiquitin-protein ligase DZIP3 (EC 2.3.2.27) (DAZ-interacting protein 3) (RING-type E3 ubiquitin transferase DZIP3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138) DZIP3 KIAA0675 Homo sapiens (Human) protein polyubiquitination [GO:0000209] cytoplasm [GO:0005737] metal ion binding [GO:0046872]; phosphatase binding [GO:0019902]; polyubiquitin modification-dependent protein binding [GO:0031593]; RNA binding [GO:0003723]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.89 -0.48782 HLNVFPAPKK 0 10.9904 0 0 10.7329 0 0 0 0 0 0 10.2019 0 11.2289 11.5442 12.1675 0 0 0 0 0 0 0 0 0 0 0 Q86Y22 CONA1_HUMAN Collagen alpha-1(XXIII) chain COL23A1 Homo sapiens (Human) extracellular matrix organization [GO:0030198] basement membrane [GO:0005604]; cell surface [GO:0009986]; collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802] 0.88529 -0.21624 AGGGGDAGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.88667 0 0 0 Q86Y25 Z354C_HUMAN "Zinc finger protein 354C (Kidney, ischemia, and developmentally-regulated protein 3) (hKID3)" ZNF354C KID3 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleoplasm [GO:0005654] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96363 -2.1997 AFNQYSSFNEHR 0 0 0 0 0 0 0 0 0 9.71713 9.87533 0 0 0 0 0 0 9.29361 0 0 0 0 0 0 0 0 0 Q86Y26 NUTM1_HUMAN NUT family member 1 (Nuclear protein in testis) NUTM1 C15orf55 NUT Homo sapiens (Human) cytoplasm [GO:0005737]; nucleus [GO:0005634] 0.80308 0.24052 VDPDLSKPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1703 0 0 Q86Y34 AGRG3_HUMAN Adhesion G protein-coupled receptor G3 (G-protein coupled receptor 97) (G-protein coupled receptor PGR26) ADGRG3 GPR97 PGR26 Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; B cell differentiation [GO:0030183]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of CREB transcription factor activity [GO:0032792]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; regulation of cell migration [GO:0030334] membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579] G protein-coupled receptor activity [GO:0004930] 0.96932 -3.1456 ALCFTKCR 0 0 12.0647 8.46185 0 0 10.8893 0 0 0 0 0 0 0 0 0 10.1204 9.98356 0 0 9.84023 0 0 0 0 0 0 Q86Y37 CACL1_HUMAN CDK2-associated and cullin domain-containing protein 1 (Cdk-associated cullin 1) CACUL1 C10orf46 CAC1 Homo sapiens (Human) G1/S transition of mitotic cell cycle [GO:0000082]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein kinase activity [GO:0045860]; ubiquitin-dependent protein catabolic process [GO:0006511] protein kinase binding [GO:0019901]; ubiquitin protein ligase binding [GO:0031625] 0.95214 -1.4758 DLKDDLIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.71303 0 0 0 0 0 0 Q86Y38 XYLT1_HUMAN Xylosyltransferase 1 (EC 2.4.2.26) (Peptide O-xylosyltransferase 1) (Xylosyltransferase I) (XT-I) (XylT-I) XYLT1 XT1 Homo sapiens (Human) chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate proteoglycan biosynthetic process [GO:0050650]; embryonic skeletal system development [GO:0048706]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan metabolic process [GO:0030203]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; ossification involved in bone maturation [GO:0043931]; proteoglycan biosynthetic process [GO:0030166] extracellular space [GO:0005615]; Golgi cis cisterna [GO:0000137]; Golgi membrane [GO:0000139] metal ion binding [GO:0046872]; protein xylosyltransferase activity [GO:0030158] 0.96883 -3.8697 GHTFPGK 0 10.6602 10.5437 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.61725 Q86Y56 DAAF5_HUMAN Dynein axonemal assembly factor 5 (HEAT repeat-containing protein 2) DNAAF5 HEATR2 Homo sapiens (Human) cilium movement [GO:0003341]; inner dynein arm assembly [GO:0036159]; outer dynein arm assembly [GO:0036158] cytoplasm [GO:0005737]; dynein axonemal particle [GO:0120293] dynein intermediate chain binding [GO:0045505] 0.82183 0.21772 TSGGMTDPEK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.34285 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86Y79 PTH_HUMAN Peptidyl-tRNA hydrolase (PTH) (EC 3.1.1.29) PTRH1 C9orf115 Homo sapiens (Human) rescue of stalled ribosome [GO:0072344] aminoacyl-tRNA hydrolase activity [GO:0004045]; RNA binding [GO:0003723] 0.88415 -0.25472 LGVAESWTRDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.61467 0 0 0 0 0 0 0 0 0 0 0 0 Q86Y82 STX12_HUMAN Syntaxin-12 STX12 Homo sapiens (Human) autophagosome assembly [GO:0000045]; cholesterol efflux [GO:0033344]; endocytic recycling [GO:0032456]; intracellular protein transport [GO:0006886]; protein stabilization [GO:0050821]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906] early endosome membrane [GO:0031901]; endomembrane system [GO:0012505]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; phagocytic vesicle [GO:0045335]; phagophore assembly site [GO:0000407]; postsynaptic recycling endosome [GO:0098837]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; SNARE complex [GO:0031201]; synaptic vesicle [GO:0008021]; vesicle [GO:0031982] SNAP receptor activity [GO:0005484]; SNARE binding [GO:0000149] 0.90917 -0.74506 AGSRLSAEERQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.39481 0 0 0 0 Q86Y91 KI18B_HUMAN Kinesin-like protein KIF18B KIF18B Homo sapiens (Human) cell division [GO:0051301]; microtubule depolymerization [GO:0007019]; microtubule-based movement [GO:0007018]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; regulation of cell division [GO:0051302] astral microtubule [GO:0000235]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinesin complex [GO:0005871]; microtubule end [GO:1990752]; microtubule plus-end [GO:0035371]; mitotic spindle astral microtubule [GO:0061673]; mitotic spindle midzone [GO:1990023]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; cytoskeletal motor activity [GO:0003774]; kinesin binding [GO:0019894]; microtubule binding [GO:0008017]; plus-end-directed microtubule motor activity [GO:0008574] 0.93284 -1.2657 KGKDLTFVFDR 0 0 0 0 0 8.67009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86YA3 ZGRF1_HUMAN Protein ZGRF1 (GRF-type zinc finger domain-containing protein 1) ZGRF1 C4orf21 Homo sapiens (Human) double-strand break repair [GO:0006302] membrane [GO:0016020]; site of double-strand break [GO:0035861] helicase activity [GO:0004386]; zinc ion binding [GO:0008270] 0.88438 -0.19771 FTGFQGPR 0 0 0 0 0 0 11.8632 0 0 0 0 0 0 10.1752 0 0 0 0 0 0 9.39795 0 0 0 0 0 9.3544 Q86YB7 ECHD2_HUMAN "Enoyl-CoA hydratase domain-containing protein 2, mitochondrial" ECHDC2 Homo sapiens (Human) fatty acid beta-oxidation [GO:0006635] mitochondrion [GO:0005739] lyase activity [GO:0016829] 0.96165 -2.5683 DRLEGMAAFR 0 0 0 0 0 0 0 0 0 0 9.56468 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3387 0 Q86YB8 ERO1B_HUMAN ERO1-like protein beta (ERO1-L-beta) (EC 1.8.4.-) (Endoplasmic reticulum oxidoreductase beta) (Endoplasmic reticulum oxidoreductin-1-like protein B) (Oxidoreductin-1-L-beta) ERO1B ERO1LB Homo sapiens (Human) insulin processing [GO:0030070]; protein folding [GO:0006457]; protein folding in endoplasmic reticulum [GO:0034975] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789] FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]; protein-disulfide reductase activity [GO:0015035]; thiol oxidase activity [GO:0016972]; unfolded protein binding [GO:0051082] 0.95192 -1.3966 EAFIDWAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.25934 0 0 0 9.46921 0 0 0 0 Q86YC2 PALB2_HUMAN Partner and localizer of BRCA2 PALB2 FANCN Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; double-strand break repair via homologous recombination [GO:0000724]; embryonic organ development [GO:0048568]; inner cell mass cell proliferation [GO:0001833]; mesoderm development [GO:0007498]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; post-anal tail morphogenesis [GO:0036342]; somitogenesis [GO:0001756] DNA repair complex [GO:1990391]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] DNA binding [GO:0003677] 0.92302 -1.1471 DASKNLNLSNEETDQSEIR 0 0 0 0 0 0 0 10.559 0 0 0 0 0 0 0 0 8.98108 0 0 0 0 0 0 0 0 0 0 Q86YC3 LRC33_HUMAN Transforming growth factor beta activator LRRC33 (Leucine-rich repeat-containing protein 33) (Negative regulator of reactive oxygen species) NRROS LRRC33 UNQ3030/PRO9833 Homo sapiens (Human) immune response [GO:0006955]; inflammatory response [GO:0006954]; microglia development [GO:0014005]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; superoxide metabolic process [GO:0006801]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transforming growth factor beta1 activation [GO:0036364] cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; plasma membrane [GO:0005886] transforming growth factor beta binding [GO:0050431] 0.91364 -0.78523 RNSLTALPQK 0 0 0 0 0 0 0 0 0 9.10617 9.03757 8.82868 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86YD1 PTOV1_HUMAN Prostate tumor-overexpressed gene 1 protein (PTOV-1) (Activator interaction domain-containing protein 2) PTOV1 ACID2 PP642 UNQ6127/PRO20092 Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944] nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; transcription regulator complex [GO:0005667] 0.84277 0.14095 IFMGLIPYDQSGFVSAIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.96142 0 0 0 0 0 0 0 0 0 0 0 Q86YE8 ZN573_HUMAN Zinc finger protein 573 ZNF573 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.92431 -0.95055 LFECKQCGKTYTTGSK 0 0 0 0 12.7826 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86YF9 DZIP1_HUMAN Cilium assembly protein DZIP1 (DAZ-interacting protein 1/2) (DAZ-interacting zinc finger protein 1) DZIP1 DZIP DZIP2 KIAA0996 Homo sapiens (Human) ciliary basal body organization [GO:0032053]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; germ cell development [GO:0007281]; heart development [GO:0007507]; maintenance of protein location in cell [GO:0032507]; positive regulation of cilium assembly [GO:0045724]; positive regulation of protein localization to cilium [GO:1903566]; protein localization to cilium [GO:0061512]; protein-containing complex localization to centriolar satellite [GO:0140706]; regulation of protein binding [GO:0043393]; smoothened signaling pathway [GO:0007224]; sperm flagellum assembly [GO:0120316]; spermatogenesis [GO:0007283] centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary base [GO:0097546]; ciliary transition fiber [GO:0097539]; cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] BBSome binding [GO:0062063]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090] 0.96771 -2.9013 AFMNQAFLQSHIQR 0 0 0 0 0 0 0 13.5492 13.5303 0 0 13.5233 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.57918 Q86YH2 Z280B_HUMAN Zinc finger protein 280B (5'OY11.1) (Suppressor of hairy wing homolog 2) (Zinc finger protein 279) (Zinc finger protein 632) ZNF280B SUHW2 ZNF279 ZNF632 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.89018 -0.47774 VTPGSWSRR 0 0 0 0 0 0 0 16.2626 0 0 0 0 0 0 0 0 0 0 0 0 0 13.021 0 12.9767 0 0 15.0832 Q86YI8 PHF13_HUMAN PHD finger protein 13 (Survival time-associated PHD finger protein in ovarian cancer 1) (SPOC1) PHF13 Homo sapiens (Human) cell division [GO:0051301]; chromatin organization [GO:0006325]; chromosome segregation [GO:0007059]; mitotic cell cycle [GO:0000278]; mitotic chromosome condensation [GO:0007076] nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; metal ion binding [GO:0046872]; methylated histone binding [GO:0035064] 0.95391 -1.5012 DSDAPGKEGYR 0 0 0 10.3792 0 0 0 0 10.756 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86YJ6 THNS2_HUMAN Threonine synthase-like 2 (TSH2) (EC 4.2.3.-) (Secreted osteoclastogenic factor of activated T-cells) (SOFAT) THNSL2 Homo sapiens (Human) 2-oxobutyrate biosynthetic process [GO:0046360]; dephosphorylation [GO:0016311]; serine family amino acid catabolic process [GO:0009071] extracellular space [GO:0005615] cytokine activity [GO:0005125]; lyase activity [GO:0016829]; pyridoxal phosphate binding [GO:0030170]; serine binding [GO:0070905] 0.8033 0.23763 ALMEQFER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.82847 Q86YJ7 AN13B_HUMAN Ankyrin repeat domain-containing protein 13B ANKRD13B Homo sapiens (Human) negative regulation of receptor internalization [GO:0002091] cytoplasm [GO:0005737]; early endosome [GO:0005769]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] ubiquitin-dependent protein binding [GO:0140036] 0.89632 -0.54272 AQDFYVEMK 0 0 0 0 0 0 0 0 0 0 11.1652 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86YM7 HOME1_HUMAN Homer protein homolog 1 (Homer-1) HOMER1 SYN47 Homo sapiens (Human) "behavioral response to cocaine [GO:0048148]; chemical synaptic transmission [GO:0007268]; circadian rhythm [GO:0007623]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; phospholipase C-activating G protein-coupled glutamate receptor signaling pathway [GO:0007206]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of signal transduction [GO:0009967]; protein localization to synapse [GO:0035418]; protein tetramerization [GO:0051262]; regulation of calcium ion import [GO:0090279]; regulation of cation channel activity [GO:2001257]; regulation of dendritic spine maintenance [GO:1902950]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of store-operated calcium entry [GO:2001256]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to calcium ion [GO:0051592]; response to nicotine [GO:0035094]; skeletal muscle contraction [GO:0003009]; skeletal muscle fiber development [GO:0048741]" apical part of cell [GO:0045177]; axon [GO:0030424]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; glutamatergic synapse [GO:0098978]; neuron spine [GO:0044309]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; Z disc [GO:0030018] G protein-coupled glutamate receptor binding [GO:0035256]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; signaling adaptor activity [GO:0035591]; structural constituent of postsynapse [GO:0099186]; transmembrane transporter binding [GO:0044325]; type 5 metabotropic glutamate receptor binding [GO:0031802] 0.41943 0.67957 AHVFQIDPNTK 0 0 0 0 0 0 0 0 0 0 0 12.7099 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86YP4 P66A_HUMAN Transcriptional repressor p66-alpha (Hp66alpha) (GATA zinc finger domain-containing protein 2A) GATAD2A Homo sapiens (Human) chromatin remodeling [GO:0006338]; DNA methylation [GO:0006306]; histone deacetylation [GO:0016575]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cell fate specification [GO:0042659]; regulation of stem cell differentiation [GO:2000736] nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NuRD complex [GO:0016581] metal ion binding [GO:0046872]; protein-macromolecule adaptor activity [GO:0030674]; sequence-specific DNA binding [GO:0043565] 0.32905 0.78024 KALKVEHTSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.99531 0 Q86YR5 GPSM1_HUMAN G-protein-signaling modulator 1 (Activator of G-protein signaling 3) GPSM1 AGS3 Homo sapiens (Human) cell differentiation [GO:0030154]; establishment of mitotic spindle orientation [GO:0000132]; negative regulation of GTPase activity [GO:0034260]; negative regulation of guanyl-nucleotide exchange factor activity [GO:1905098]; nervous system development [GO:0007399]; positive regulation of macroautophagy [GO:0016239] cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] G-protein alpha-subunit binding [GO:0001965]; GDP-dissociation inhibitor activity [GO:0005092] 0.9515 -1.4296 TIGDRMGEAKASGNLGNTLK 10.503 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86YR7 MF2L2_HUMAN Probable guanine nucleotide exchange factor MCF2L2 (Dbs-related Rho family guanine nucleotide exchange factor) (MCF2-transforming sequence-like protein 2) MCF2L2 ARHGEF22 DRG KIAA0861 Homo sapiens (Human) regulation of response to stimulus [GO:0048583] cytoplasm [GO:0005737] guanyl-nucleotide exchange factor activity [GO:0005085] 0.29787 0.81004 AGASTGR 0 0 0 0 0 0 0 0 0 8.80135 9.68996 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3323 0 0 Q86YS3 RFIP4_HUMAN Rab11 family-interacting protein 4 (FIP4-Rab11) (Rab11-FIP4) (Arfophilin-2) RAB11FIP4 ARFO2 KIAA1821 Homo sapiens (Human) endocytic recycling [GO:0032456]; regulation of cytokinesis [GO:0032465] cleavage furrow [GO:0032154]; endocytic vesicle [GO:0030139]; endosome [GO:0005768]; extracellular space [GO:0005615]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; recycling endosome membrane [GO:0055038]; spindle [GO:0005819] calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; small GTPase binding [GO:0031267] 0.96992 -3.0862 ANSPNRKISSTAFGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4109 0 0 9.10766 0 0 0 0 0 0 Q86YS7 C2CD5_HUMAN C2 domain-containing protein 5 (C2 domain-containing phosphoprotein of 138 kDa) C2CD5 CDP138 KIAA0528 Homo sapiens (Human) cellular response to insulin stimulus [GO:0032869]; insulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028]; intracellular protein transmembrane transport [GO:0065002]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of vesicle fusion [GO:0031340]; protein localization to plasma membrane [GO:0072659] cell cortex [GO:0005938]; centriolar satellite [GO:0034451]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587] calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544] 0.56714 0.48436 AIGTACTLDK 0 0 9.27687 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.14736 Q86YT6 MIB1_HUMAN E3 ubiquitin-protein ligase MIB1 (EC 2.3.2.27) (DAPK-interacting protein 1) (DIP-1) (Mind bomb homolog 1) (RING-type E3 ubiquitin transferase MIB1) (Zinc finger ZZ type with ankyrin repeat domain protein 2) MIB1 DIP1 KIAA1323 ZZANK2 Homo sapiens (Human) blood vessel development [GO:0001568]; endocytosis [GO:0006897]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; negative regulation of neuron differentiation [GO:0045665]; neural tube formation [GO:0001841]; neuron differentiation [GO:0030182]; Notch signaling pathway [GO:0007219]; positive regulation of endocytosis [GO:0045807]; protein ubiquitination [GO:0016567]; somitogenesis [GO:0001756]; ubiquitin-dependent protein catabolic process [GO:0006511] centrosome [GO:0005813]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.93421 -1.2905 NNRVMVEGVGAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.96513 0 0 0 10.0779 10.067 Q86YT9 JAML_HUMAN Junctional adhesion molecule-like (Adhesion molecule interacting with CXADR antigen 1) (Dendritic cell-specific protein CREA7-1) JAML AMICA1 UNQ722/PRO1387 Homo sapiens (Human) gamma-delta T cell activation [GO:0046629]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; monocyte extravasation [GO:0035696]; neutrophil chemotaxis [GO:0030593]; neutrophil extravasation [GO:0072672]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054] bicellular tight junction [GO:0005923]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; protein homodimerization activity [GO:0042803] 0.88465 -0.1305 IDWTLSPGEHAK 0 0 0 0 0 0 0 0 0 0 0 10.0447 0 11.1737 0 0 0 0 0 0 9.44878 0 8.84273 0 0 9.89842 0 Q86YV0 RASL3_HUMAN RAS protein activator like-3 RASAL3 Homo sapiens (Human) negative regulation of Ras protein signal transduction [GO:0046580]; positive regulation of NK T cell proliferation [GO:0051142]; regulation of GTPase activity [GO:0043087] cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020] GTPase activator activity [GO:0005096]; identical protein binding [GO:0042802] 0.96896 -6.6786 DPPSPSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.97571 0 0 0 0 0 0 0 0 10.3748 8.4654 Q86YV5 PRAG1_HUMAN Inactive tyrosine-protein kinase PRAG1 (PEAK1-related kinase-activating pseudokinase 1) (Pragmin) (Sugen kinase 223) (SgK223) PRAG1 SGK223 Homo sapiens (Human) cell migration [GO:0016477]; negative regulation of neuron projection development [GO:0010977]; positive regulation of Rho protein signal transduction [GO:0035025]; protein phosphorylation [GO:0006468]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of Notch signaling pathway [GO:0008593] cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634] identical protein binding [GO:0042802]; protein kinase activity [GO:0004672] 0.96209 -2.4938 DCSPTCWEQGKCSGPAEQEK 0 9.06334 8.86746 0 0 0 8.88899 0 8.42614 15.522 0 0 0 0 0 9.03155 0 0 0 0 10.4225 0 0 8.29476 0 0 9.96896 Q86YW9 MD12L_HUMAN Mediator of RNA polymerase II transcription subunit 12-like protein (Mediator complex subunit 12-like protein) (Thyroid hormone receptor-associated-like protein) (Trinucleotide repeat-containing gene 11 protein-like) MED12L KIAA1635 TNRC11L TRALP TRALPUSH PRO0314 Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944] mediator complex [GO:0016592] beta-catenin binding [GO:0008013]; transcription coactivator activity [GO:0003713] 0.95224 -1.475 AYMNLVKKLK 0 0 0 0 0 0 0 0 0 11.2954 0 0 0 11.7582 10.1098 0 0 10.5681 0 0 0 9.5775 0 0 0 0 0 Q86YZ3 HORN_HUMAN Hornerin HRNR S100A18 Homo sapiens (Human) cell envelope organization [GO:0043163]; establishment of skin barrier [GO:0061436]; keratinization [GO:0031424] azurophil granule lumen [GO:0035578]; collagen-containing extracellular matrix [GO:0062023]; cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; keratohyalin granule [GO:0036457]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] calcium ion binding [GO:0005509]; transition metal ion binding [GO:0046914] 0 3.2801 GPYESGSGHSSGLGHR 0 0 0 0 0 0 9.01809 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q86Z14 KLOTB_HUMAN Beta-klotho (BKL) (BetaKlotho) (Klotho beta-like protein) KLB Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway [GO:0090080] plasma membrane [GO:0005886] "fibroblast growth factor binding [GO:0017134]; fibroblast growth factor receptor binding [GO:0005104]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]" 0.93895 -1.3221 AKSSIQFYNK 0 0 0 0 0 0 0 0 0 0 0 12.6631 0 0 0 0 8.60626 0 0 0 0 0 0 0 0 0 0 Q86Z20 CC125_HUMAN Coiled-coil domain-containing protein 125 (Protein kenae) CCDC125 KENAE Homo sapiens (Human) activation of GTPase activity [GO:0090630]; negative regulation of cell motility [GO:2000146]; negative regulation of Rho protein signal transduction [GO:0035024] cytoplasm [GO:0005737] identical protein binding [GO:0042802] 0.96181 -2.5864 NIEESWIQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1591 0 11.1634 0 0 0 0 0 0 0 0 0 11.6492 Q86Z23 C1QL4_HUMAN Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11) C1QL4 CTRP11 Homo sapiens (Human) ERK1 and ERK2 cascade [GO:0070371]; fibroblast proliferation [GO:0048144]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of fibroblast proliferation [GO:0048147] collagen trimer [GO:0005581]; extracellular space [GO:0005615] identical protein binding [GO:0042802] 0.29853 0.81252 GPPGPPGPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.86901 0 0 0 0 0 0 0 0 0 0 0 0 Q8IU60 DCP2_HUMAN m7GpppN-mRNA hydrolase (EC 3.6.1.62) (Nucleoside diphosphate-linked moiety X motif 20) (Nudix motif 20) (mRNA-decapping enzyme 2) (hDpc) DCP2 NUDT20 Homo sapiens (Human) "deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; histone mRNA catabolic process [GO:0071044]; mRNA catabolic process [GO:0006402]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of mRNA stability [GO:0043488]; regulation of telomerase RNA localization to Cajal body [GO:1904872]" cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; RISC complex [GO:0016442] "5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity [GO:0140933]; 5'-3' RNA exonuclease activity [GO:0004534]; manganese ion binding [GO:0030145]; RNA exonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; telomerase RNA binding [GO:0070034]" 0.96967 -4.0573 DTKFNPK 0 0 0 0 0 11.1671 0 0 0 0 10.1433 0 10.5304 0 0 0 0 0 0 9.39397 0 10.5236 9.09816 0 0 9.9319 0 Q8IU68 TMC8_HUMAN Transmembrane channel-like protein 8 (Epidermodysplasia verruciformis protein 2) TMC8 EVER2 EVIN2 Homo sapiens (Human) intracellular zinc ion homeostasis [GO:0006882]; negative regulation of protein binding [GO:0032091]; negative regulation of protein-containing complex assembly [GO:0031333]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041] cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886] mechanosensitive monoatomic ion channel activity [GO:0008381]; protein sequestering activity [GO:0140311]; tumor necrosis factor binding [GO:0043120] 0.86368 0.081751 FQLMQQQTRAQTACR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0702 0 0 Q8IU81 I2BP1_HUMAN Interferon regulatory factor 2-binding protein 1 (IRF-2-binding protein 1) (IRF-2BP1) (Probable E3 ubiquitin-protein ligase IRF2BP1) (EC 2.3.2.27) (Probable RING-type E3 ubiquitin transferase IRF2BP1) IRF2BP1 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; protein polyubiquitination [GO:0000209]; regulation of transcription by RNA polymerase II [GO:0006357] nucleoplasm [GO:0005654]; nucleus [GO:0005634] metal ion binding [GO:0046872]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase activity [GO:0061630] 0.9465 -1.3494 ALASSGFKYLEYERR 0 0 0 0 0 0 0 0 0 0 10.6235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IU85 KCC1D_HUMAN Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I delta) (CaM kinase ID) (CaM-KI delta) (CaMKI delta) (CaMKID) (CaMKI-like protein kinase) (CKLiK) CAMK1D CAMKID Homo sapiens (Human) inflammatory response [GO:0006954]; negative regulation of apoptotic process [GO:0043066]; nervous system development [GO:0007399]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of neuron projection development [GO:0010976]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of phagocytosis [GO:0050766]; positive regulation of respiratory burst [GO:0060267]; regulation of dendrite development [GO:0050773]; regulation of granulocyte chemotaxis [GO:0071622] cytoplasm [GO:0005737]; nucleus [GO:0005634] ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; protein serine kinase activity [GO:0106310] 0.92437 -1.042 RYTCEQAARHPWIAGDTALNK 0 0 0 0 0 10.2025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IUA7 ABCA9_HUMAN ATP-binding cassette sub-family A member 9 (EC 7.6.2.-) ABCA9 Homo sapiens (Human) lipid transport [GO:0006869] intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020] ABC-type transporter activity [GO:0140359]; ATP binding [GO:0005524]; ATPase-coupled transmembrane transporter activity [GO:0042626]; lipid transporter activity [GO:0005319] 0.9183 -0.88474 LFAKIKGILPHEVEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1063 0 0 0 0 0 0 0 0 0 0 0 Q8IUB2 WFDC3_HUMAN WAP four-disulfide core domain protein 3 (Putative protease inhibitor WAP14) WFDC3 WAP14 Homo sapiens (Human) antibacterial humoral response [GO:0019731]; innate immune response [GO:0045087]; negative regulation of peptidase activity [GO:0010466] extracellular region [GO:0005576] serine-type endopeptidase inhibitor activity [GO:0004867] 0.88489 -0.2429 LTMNPNWTVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2804 0 Q8IUB3 WF10B_HUMAN Protein WFDC10B WFDC10B WAP12 Homo sapiens (Human) antibacterial humoral response [GO:0019731]; innate immune response [GO:0045087] extracellular region [GO:0005576] peptidase inhibitor activity [GO:0030414] 0.83254 0.20159 RPSIDLCIHHCSYFQKCETNK 0 0 0 10.9559 0 0 0 9.8305 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IUC6 TCAM1_HUMAN "TIR domain-containing adapter molecule 1 (TICAM-1) (Proline-rich, vinculin and TIR domain-containing protein B) (Putative NF-kappa-B-activating protein 502H) (Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta) (MyD88-3) (TIR domain-containing adapter protein inducing IFN-beta)" TICAM1 PRVTIRB TRIF Homo sapiens (Human) apoptotic signaling pathway [GO:0097190]; B cell proliferation [GO:0042100]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidised low-density lipoprotein particle stimulus [GO:0140052]; defense response to virus [GO:0051607]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage activation involved in immune response [GO:0002281]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of autophagy [GO:0010508]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of myeloid dendritic cell cytokine production [GO:0002735]; positive regulation of natural killer cell activation [GO:0032816]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon production [GO:0032481]; regulation of protein-containing complex assembly [GO:0043254]; response to exogenous dsRNA [GO:0043330]; toll-like receptor signaling pathway [GO:0002224]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666] autophagosome [GO:0005776]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; endosome membrane [GO:0010008]; mitochondrion [GO:0005739]; ripoptosome [GO:0097342] molecular adaptor activity [GO:0060090]; protein kinase binding [GO:0019901]; ubiquitin-protein transferase activator activity [GO:0097027] 0.96786 -2.8955 GSQAPEDKTQEAE 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.6227 0 0 0 0 0 0 0 0 0 0 0 0 Q8IUD2 RB6I2_HUMAN ELKS/Rab6-interacting/CAST family member 1 (ERC-1) (Rab6-interacting protein 2) ERC1 ELKS KIAA1081 RAB6IP2 Homo sapiens (Human) "I-kappaB phosphorylation [GO:0007252]; maintenance of presynaptic active zone structure [GO:0048790]; neuromuscular synaptic transmission [GO:0007274]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein transport [GO:0015031]; regulation of DNA-templated transcription [GO:0006355]; regulation of synaptic plasticity [GO:0048167]; retrograde transport, endosome to Golgi [GO:0042147]" centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; cytoskeleton of presynaptic active zone [GO:0048788]; Golgi membrane [GO:0000139]; IkappaB kinase complex [GO:0008385]; presynaptic membrane [GO:0042734]; synapse [GO:0045202] cadherin binding [GO:0045296]; PDZ domain binding [GO:0030165]; small GTPase binding [GO:0031267]; structural constituent of presynaptic active zone [GO:0098882] 0.96977 -5.0406 EEEMKQMEVYR 0 0 0 0 0 0 0 0 0 0 0 0 9.57962 0 13.2445 0 0 0 0 12.2849 0 0 0 0 10.5614 0 0 Q8IUG5 MY18B_HUMAN Unconventional myosin-XVIIIb MYO18B Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; in utero embryonic development [GO:0001701]; vasculogenesis [GO:0001570] cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; myosin filament [GO:0032982]; myosin II complex [GO:0016460]; nucleus [GO:0005634]; unconventional myosin complex [GO:0016461]; Z disc [GO:0030018] actin filament binding [GO:0051015]; ATP binding [GO:0005524]; cytoskeletal motor activity [GO:0003774] 0.96902 -3.595 AGESWDKKEK 0 8.72663 0 0 0 0 0 0 0 9.55273 12.0514 11.5151 0 0 0 10.1115 0 0 0 0 9.87593 0 0 0 10.2554 0 0 Q8IUH3 RBM45_HUMAN RNA-binding protein 45 (Developmentally-regulated RNA-binding protein 1) (RB-1) (RNA-binding motif protein 45) RBM45 DRB1 DRBP1 Homo sapiens (Human) cell differentiation [GO:0030154]; nervous system development [GO:0007399] cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] identical protein binding [GO:0042802]; RNA binding [GO:0003723] 0.55853 0.54748 IFVMIPK 0 14.6026 0 0 10.6264 0 14.0905 0 0 0 0 14.6321 0 0 12.7063 13.4605 13.3723 0 0 0 0 0 0 0 0 0 0 Q8IUK5 PLDX1_HUMAN Plexin domain-containing protein 1 (Tumor endothelial marker 3) (Tumor endothelial marker 7) PLXDC1 TEM3 TEM7 Homo sapiens (Human) angiogenesis [GO:0001525]; spinal cord development [GO:0021510] bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] 0.89699 -0.53301 ELWVDVAEANR 0 0 0 0 0 0 0 0 0 9.36359 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IUM7 NPAS4_HUMAN Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (Class E basic helix-loop-helix protein 79) (bHLHe79) (HLH-PAS transcription factor NXF) (PAS domain-containing protein 10) NPAS4 BHLHE79 NXF PASD10 Homo sapiens (Human) "cell differentiation [GO:0030154]; cellular response to corticosterone stimulus [GO:0071386]; excitatory postsynaptic potential [GO:0060079]; inhibitory postsynaptic potential [GO:0060080]; inhibitory synapse assembly [GO:1904862]; learning [GO:0007612]; long-term memory [GO:0007616]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of synaptic plasticity [GO:0048167]; regulation of synaptic transmission, GABAergic [GO:0032228]; regulation of transcription by RNA polymerase II [GO:0006357]; short-term memory [GO:0007614]; social behavior [GO:0035176]" chromatin [GO:0000785]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; postsynapse [GO:0098794]; transcription regulator complex [GO:0005667] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.86425 0.079923 LLAESGDIQAEMVVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6986 0 0 0 0 0 0 0 0 0 0 Q8IUQ0 CLVS1_HUMAN Clavesin-1 (Cellular retinaldehyde-binding protein-like) (Retinaldehyde-binding protein 1-like 1) (clathrin vesicle-associated Sec14 protein 1) CLVS1 CRALBPL RLBP1L1 Homo sapiens (Human) lysosome organization [GO:0007040] clathrin-coated vesicle [GO:0030136]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588] "phosphatidylinositol bisphosphate binding [GO:1902936]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]" 0.94055 -1.3098 QASKLTPSILK 0 0 0 0 0 9.35154 0 10.5133 0 0 0 9.95707 0 9.16805 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IUR5 TMTC1_HUMAN Protein O-mannosyl-transferase TMTC1 (EC 2.4.1.109) (Transmembrane and TPR repeat-containing protein 1) TMTC1 ARG99 Homo sapiens (Human) protein O-linked mannosylation [GO:0035269]; RNA processing [GO:0006396] endoplasmic reticulum [GO:0005783]; membrane [GO:0016020] dolichyl-phosphate-mannose-protein mannosyltransferase activity [GO:0004169]; mannosyltransferase activity [GO:0000030] 0.94764 -1.3584 MVVTTSARGGGGDR 0 0 0 0 0 0 0 0 8.81372 0 0 0 10.473 0 0 11.9965 0 11.9616 0 9.4113 0 0 0 0 0 0 0 Q8IUR6 CRERF_HUMAN CREB3 regulatory factor (Luman recruitment factor) (LRF) CREBRF C5orf41 Homo sapiens (Human) negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of intracellular transport [GO:0032388]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein transport [GO:0051222]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; response to endoplasmic reticulum stress [GO:0034976]; response to unfolded protein [GO:0006986] cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.95436 -1.5125 ASKPTSSTQIMVK 0 0 0 0 0 0 9.00149 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IUR7 ARMC8_HUMAN Armadillo repeat-containing protein 8 ARMC8 S863-2 Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; GID complex [GO:0034657]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; ubiquitin ligase complex [GO:0000151] 0.88254 -0.068065 DKPIEMQLTSAK 0 0 0 0 0 0 0 0 0 0 0 0 0 8.85449 0 0 0 0 0 9.46526 0 0 0 0 0 0 0 Q8IUW3 SPA2L_HUMAN Spermatogenesis-associated protein 2-like protein (SPATA2-like protein) SPATA2L C16orf76 Homo sapiens (Human) cytoplasm [GO:0005737] 0.90617 -0.73183 ELSRPGDLATPESSAAASPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.0179 0 0 0 0 0 0 0 0 0 0 Q8IUX4 ABC3F_HUMAN DNA dC->dU-editing enzyme APOBEC-3F (EC 3.5.4.38) (Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F) (A3F) APOBEC3F Homo sapiens (Human) base conversion or substitution editing [GO:0016553]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; positive regulation of defense response to virus by host [GO:0002230]; retrotransposon silencing [GO:0010526] apolipoprotein B mRNA editing enzyme complex [GO:0030895]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; P-body [GO:0000932]; ribonucleoprotein complex [GO:1990904] cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270] 0.94705 -1.3559 NTVERMYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3263 0 0 0 0 0 Q8IUX8 EGFL6_HUMAN Epidermal growth factor-like protein 6 (EGF-like protein 6) (MAM and EGF domains-containing gene protein) EGFL6 MAEG PP648 UNQ281/PRO320 Homo sapiens (Human) cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; extracellular matrix organization [GO:0030198]; positive regulation of cell-substrate adhesion [GO:0010811] basement membrane [GO:0005604]; extracellular space [GO:0005615]; membrane [GO:0016020] calcium ion binding [GO:0005509]; integrin binding [GO:0005178] 0.96944 -5.5469 ALKNDIEER 0 0 0 0 0 8.67867 0 0 0 0 0 0 0 0 0 0 0 0 0 9.64953 10.1473 10.7447 0 9.42913 0 0 10.6526 Q8IUZ0 LRC49_HUMAN Leucine-rich repeat-containing protein 49 (Centriolar satellite-associated tubulin polyglutamylase complex regulator 2) (Tubulin polyglutamylase complex subunit 4) (PGs4) LRRC49 CSTPP2 Homo sapiens (Human) centriolar satellite [GO:0034451]; cytoplasm [GO:0005737]; microtubule [GO:0005874] 0.96842 -3.6456 IKFPNSLHLKFK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.19296 9.17198 0 0 0 0 0 0 0 0 0 0 0 0 Q8IUZ5 AT2L2_HUMAN 5-phosphohydroxy-L-lysine phospho-lyase (EC 4.2.3.134) (Alanine--glyoxylate aminotransferase 2-like 2) PHYKPL AGXT2L2 PP9286 Homo sapiens (Human) mitochondrial matrix [GO:0005759] identical protein binding [GO:0042802]; lyase activity [GO:0016829]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483] 0.965 -2.7056 SCETLRLQP 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.99152 0 0 0 0 0 0 10.597 0 Q8IV04 TB10C_HUMAN Carabin (TBC1 domain family member 10C) TBC1D10C Homo sapiens (Human) "activation of GTPase activity [GO:0090630]; B cell activation [GO:0042113]; calcineurin-NFAT signaling cascade [GO:0033173]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of B cell activation [GO:0050869]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; retrograde transport, endosome to Golgi [GO:0042147]" cytosol [GO:0005829]; ficolin-1-rich granule membrane [GO:0101003]; filopodium membrane [GO:0031527]; membrane [GO:0016020]; plasma membrane [GO:0005886] GTPase activator activity [GO:0005096] 0.90735 -0.71044 GSTSFLDTR 0 0 0 0 0 0 0 9.31188 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IV32 CCD71_HUMAN Coiled-coil domain-containing protein 71 CCDC71 Homo sapiens (Human) 0.91819 -0.87035 AQAKVAR 0 0 0 0 0 0 0 0 10.5726 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IV33 K0825_HUMAN Uncharacterized protein KIAA0825 KIAA0825 C5orf36 Homo sapiens (Human) 0.51598 0.59302 DSNLDVIAHGYQSTMLK 0 0 0 0 0 0 9.60125 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.75069 0 0 9.02264 0 0 Q8IV35 WDR49_HUMAN WD repeat-containing protein 49 WDR49 Homo sapiens (Human) 0.90585 -0.72593 EILHHERK 12.266 0 0 0 9.38236 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IV36 HID1_HUMAN Protein HID1 (Down-regulated in multiple cancers 1) (HID1 domain-containing protein) (Protein hid-1 homolog) HID1 C17orf28 DMC1 Homo sapiens (Human) cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of Golgi membrane [GO:0090498]; Golgi apparatus [GO:0005794]; Golgi medial cisterna [GO:0005797]; Golgi trans cisterna [GO:0000138]; membrane [GO:0016020] 0.8989 -0.64383 EESPSNLATLCYKAVEK 0 0 0 0 9.21031 10.438 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IV42 PSTK_HUMAN L-seryl-tRNA(Sec) kinase (EC 2.7.1.164) (O-phosphoseryl-tRNA(Sec) kinase) PSTK C10orf89 Homo sapiens (Human) phosphorylation [GO:0016310]; translation [GO:0006412] ATP binding [GO:0005524]; kinase activity [GO:0016301]; L-seryl-tRNA(Sec) kinase activity [GO:0043915]; tRNA binding [GO:0000049] 0.40501 0.7011 GNQEAFSEMTFK 0 0 0 0 0 0 11.113 0 0 0 10.0493 0 0 0 0 0 0 13.3869 9.85414 9.8445 0 0 0 0 0 0 0 Q8IV48 ERI1_HUMAN 3'-5' exoribonuclease 1 (EC 3.1.-.-) (3'-5' exonuclease ERI1) (Eri-1 homolog) (Histone mRNA 3'-end-specific exoribonuclease) (Histone mRNA 3'-exonuclease 1) (Protein 3'hExo) (HEXO) ERI1 3'EXO THEX1 Homo sapiens (Human) "exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; RNA-mediated gene silencing [GO:0031047]; rRNA 3'-end processing [GO:0031125]" cytoplasm [GO:0005737]; histone pre-mRNA 3'end processing complex [GO:0071204]; nucleolus [GO:0005730]; nucleus [GO:0005634] 3'-5' exonuclease activity [GO:0008408]; 3'-5'-RNA exonuclease activity [GO:0000175]; histone pre-mRNA stem-loop binding [GO:0071207]; metal ion binding [GO:0046872]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843] 0.8492 0.1139 MLQDGCELRINEK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.3619 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IV50 LYSM2_HUMAN LysM and putative peptidoglycan-binding domain-containing protein 2 LYSMD2 Homo sapiens (Human) 0.7895 0.25133 DEESPYATSLYHS 0 0 10.128 0 0 0 0 10.1748 10.2345 10.8094 10.2773 0 0 0 9.97528 0 0 0 0 0 0 0 0 0 0 0 0 Q8IV56 PRR15_HUMAN Proline-rich protein 15 PRR15 Homo sapiens (Human) 0.89834 -0.56602 LYGDKSGSSRR 0 0 0 0 0 0 0 0 0 0 0 0 10.4464 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IV61 GRP3_HUMAN Ras guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1) RASGRP3 GRP3 KIAA0846 Homo sapiens (Human) MAPK cascade [GO:0000165]; positive regulation of GTPase activity [GO:0043547]; Ras protein signal transduction [GO:0007265]; small GTPase mediated signal transduction [GO:0007264] guanyl-nucleotide exchange factor complex [GO:0032045]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; diacylglycerol binding [GO:0019992]; GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; kinase binding [GO:0019900]; small GTPase binding [GO:0031267] 0.94078 -1.3289 ETHSHLSSEVTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5562 0 0 0 0 0 0 0 Q8IV63 VRK3_HUMAN Inactive serine/threonine-protein kinase VRK3 (Serine/threonine-protein pseudokinase VRK3) (Vaccinia-related kinase 3) VRK3 Homo sapiens (Human) negative regulation of ERK1 and ERK2 cascade [GO:0070373]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519] intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; protein phosphatase binding [GO:0019903]; protein serine/threonine kinase activity [GO:0004674] 0.65637 0.3955 SIQAAFK 12.9539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IV77 CNGA4_HUMAN Cyclic nucleotide-gated cation channel alpha-4 (Cyclic nucleotide-gated channel alpha-4) (CNG channel alpha-4) (CNG-4) (CNG4) CNGA4 Homo sapiens (Human) monoatomic cation transmembrane transport [GO:0098655]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608] ciliary membrane [GO:0060170]; Golgi-associated vesicle membrane [GO:0030660]; intracellular cyclic nucleotide activated cation channel complex [GO:0017071]; plasma membrane [GO:0005886] cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; intracellular cAMP-activated cation channel activity [GO:0005222]; intracellular cGMP-activated cation channel activity [GO:0005223]; protein-containing complex binding [GO:0044877] 0.96748 -2.9703 DEEGRASQEGPPGPE 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8111 0 0 0 0 0 0 Q8IVB4 SL9A9_HUMAN Sodium/hydrogen exchanger 9 (Na(+)/H(+) exchanger 9) (NHE-9) (Solute carrier family 9 member 9) SLC9A9 NHE9 Nbla00118 Homo sapiens (Human) defense response to bacterium [GO:0042742]; monoatomic ion transport [GO:0006811]; phagosome maturation [GO:0090382]; potassium ion transmembrane transport [GO:0071805]; regulation of intracellular pH [GO:0051453]; sodium ion import across plasma membrane [GO:0098719] early endosome [GO:0005769]; early endosome membrane [GO:0031901]; early phagosome [GO:0032009]; late endosome membrane [GO:0031902]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038] potassium:proton antiporter activity [GO:0015386]; sodium:proton antiporter activity [GO:0015385] 0.88408 -0.14389 AESARLFRMWYSFDHK 8.78571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IVC4 ZN584_HUMAN Zinc finger protein 584 ZNF584 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.16528 0.99162 SYECTECGKAFK 0 0 10.7051 0 0 0 0 11.641 0 8.72298 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IVD9 NUDC3_HUMAN NudC domain-containing protein 3 NUDCD3 KIAA1068 Homo sapiens (Human) cilium assembly [GO:0060271]; protein folding [GO:0006457]; protein localization to pericentriolar material [GO:1905793] cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868] unfolded protein binding [GO:0051082] 0.83605 0.19271 LTFDYHQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.15656 0 0 0 0 Q8IVE3 PKHH2_HUMAN Pleckstrin homology domain-containing family H member 2 PLEKHH2 KIAA2028 Homo sapiens (Human) negative regulation of actin filament depolymerization [GO:0030835] cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lamellipodium [GO:0030027]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] actin binding [GO:0003779] 0.96832 -2.7789 IIEEKAAKIK 0 0 0 0 0 0 13.6629 0 0 0 0 0 13.5103 13.6795 13.6453 14.2544 13.864 0 9.70738 0 0 0 0 0 0 0 8.92799 Q8IVF2 AHNK2_HUMAN Protein AHNAK2 AHNAK2 C14orf78 KIAA2019 Homo sapiens (Human) regulation of RNA splicing [GO:0043484] costamere [GO:0043034]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; T-tubule [GO:0030315] 0.96932 -6.0972 AGPGSQR 9.09231 8.95411 8.70041 0 0 0 8.68363 10.9703 10.3954 0 0 0 0 0 0 0 9.78612 10.0664 0 10.5926 9.20648 9.86423 8.81455 10.3073 11.1504 10.6484 10.0265 Q8IVF4 DYH10_HUMAN Dynein axonemal heavy chain 10 (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10) DNAH10 KIAA2017 Homo sapiens (Human) microtubule-based movement [GO:0007018] 9+2 motile cilium [GO:0097729]; axoneme [GO:0005930]; dynein complex [GO:0030286]; microtubule [GO:0005874] ATP binding [GO:0005524]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; minus-end-directed microtubule motor activity [GO:0008569] 0.9689 -13.748 DLEKSLER 0 11.6773 0 0 0 10.8642 9.19269 10.3818 0 8.86576 0 17.9591 12.0992 11.1724 9.22033 0 9.87123 10.9525 10.6548 0 10.0692 9.01842 0 9.64258 10.5832 0 11.0533 Q8IVF5 TIAM2_HUMAN Rho guanine nucleotide exchange factor TIAM2 (SIF and TIAM1-like exchange factor) (T-lymphoma invasion and metastasis-inducing protein 2) (TIAM-2) TIAM2 KIAA2016 STEF Homo sapiens (Human) activation of GTPase activity [GO:0090630]; positive regulation of axonogenesis [GO:0050772]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; membrane [GO:0016020]; perikaryon [GO:0043204]; synapse [GO:0045202] GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085] 0.96955 -4.9623 HGKEDTLR 0 0 0 0 0 0 0 0 0 0 13.2616 0 0 0 0 0 0 0 0 11.1651 10.0084 0 0 0 0 0 12.1536 Q8IVF6 AN18A_HUMAN Ankyrin repeat domain-containing protein 18A ANKRD18A KIAA2015 Homo sapiens (Human) 0.88418 -0.055108 EAVSSECVNLAK 0 0 0 0 0 0 0 0 0 0 0 0 9.25753 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IVF7 FMNL3_HUMAN Formin-like protein 3 (Formin homology 2 domain-containing protein 3) (WW domain-binding protein 3) (WBP-3) FMNL3 FHOD3 FRL2 KIAA2014 WBP3 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; angiogenesis [GO:0001525]; cell migration [GO:0016477]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeleton organization [GO:0007010]; filopodium assembly [GO:0046847]; regulation of cell shape [GO:0008360] cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886] actin filament binding [GO:0051015]; GTPase activating protein binding [GO:0032794]; small GTPase binding [GO:0031267] 0.96817 -2.9195 DDVHVCILCLR 12.2575 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6759 0 0 0 9.86963 0 0 0 Q8IVG5 SAM9L_HUMAN Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like) SAMD9L C7orf6 DRIF2 KIAA2005 UEF Homo sapiens (Human) cytoplasm [GO:0005737]; early endosome [GO:0005769]; mitochondrion [GO:0005739] 0.969 -6.8863 AMKKESEGLK 0 12.59 0 0 0 0 0 0 0 0 15.4905 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5287 0 Q8IVH4 MMAA_HUMAN "Methylmalonic aciduria type A protein, mitochondrial (EC 3.6.-.-)" MMAA Homo sapiens (Human) cobalamin metabolic process [GO:0009235] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803] 0.91308 -0.78706 MKDFQDLMLASGELTAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.492 0 0 0 0 Q8IVH8 M4K3_HUMAN Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3) MAP4K3 RAB8IPL1 Homo sapiens (Human) intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; protein phosphorylation [GO:0006468]; response to tumor necrosis factor [GO:0034612]; response to UV [GO:0009411] cytoplasm [GO:0005737] ATP binding [GO:0005524]; MAP kinase kinase kinase kinase activity [GO:0008349]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.82043 0.21827 DGSLCQQQNEHR 0 0 0 0 9.0959 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IVI9 NOSTN_HUMAN Nostrin (BM247 homolog) (Nitric oxide synthase traffic inducer) (Nitric oxide synthase trafficker) (eNOS-trafficking inducer) NOSTRIN Homo sapiens (Human) actin filament organization [GO:0007015]; cell migration [GO:0016477]; endocytosis [GO:0006897]; negative regulation of DNA-templated transcription [GO:0045892]; signal transduction [GO:0007165] cytoskeleton [GO:0005856]; endocytic vesicle membrane [GO:0030666]; nucleus [GO:0005634]; plasma membrane [GO:0005886] DNA binding [GO:0003677] 0.92192 -1.125 ALYSFQAR 0 0 0 0 0 0 0 0 0 0 0 0 10.7526 0 0 0 0 0 0 0 9.74229 0 0 0 0 0 0 Q8IVL0 NAV3_HUMAN Neuron navigator 3 (Pore membrane and/or filament-interacting-like protein 1) (Steerin-3) (Unc-53 homolog 3) (unc53H3) NAV3 KIAA0938 POMFIL1 STEERIN3 Homo sapiens (Human) negative regulation of cell migration [GO:0030336]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of microtubule depolymerization [GO:0007026]; neurogenesis [GO:0022008]; positive regulation of microtubule polymerization [GO:0031116] nuclear outer membrane [GO:0005640] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; microtubule binding [GO:0008017] 0.96794 -2.894 AGTSALKTPGK 0 0 10.3373 0 0 0 0 0 0 12.546 10.2913 12.7169 0 11.0375 11.9491 10.4786 0 0 0 0 0 0 0 0 0 0 0 Q8IVL1 NAV2_HUMAN Neuron navigator 2 (EC 3.6.4.12) (Helicase APC down-regulated 1) (Pore membrane and/or filament-interacting-like protein 2) (Retinoic acid inducible in neuroblastoma 1) (Steerin-2) (Unc-53 homolog 2) (unc53H2) NAV2 HELAD1 KIAA1419 POMFIL2 RAINB1 STEERIN2 Homo sapiens (Human) glossopharyngeal nerve development [GO:0021563]; locomotory behavior [GO:0007626]; neurogenesis [GO:0022008]; optic nerve development [GO:0021554]; regulation of systemic arterial blood pressure by baroreceptor feedback [GO:0003025]; sensory perception of smell [GO:0007608]; sensory perception of sound [GO:0007605]; vagus nerve development [GO:0021564] interstitial matrix [GO:0005614]; nucleoplasm [GO:0005654] 3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; heparin binding [GO:0008201] 0.96926 -3.9924 GIAQRTFSR 0 11.3506 0 0 0 0 0 0 9.14246 9.40043 0 0 0 0 0 0 9.33537 0 0 0 9.60346 0 0 0 0 0 0 Q8IVL5 P3H2_HUMAN Prolyl 3-hydroxylase 2 (EC 1.14.11.7) (Leprecan-like protein 1) (Myxoid liposarcoma-associated protein 4) P3H2 LEPREL1 MLAT4 Homo sapiens (Human) collagen metabolic process [GO:0032963]; negative regulation of cell population proliferation [GO:0008285]; peptidyl-proline hydroxylation [GO:0019511] basement membrane [GO:0005604]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; sarcoplasmic reticulum [GO:0016529] iron ion binding [GO:0005506]; L-ascorbic acid binding [GO:0031418]; procollagen-proline 3-dioxygenase activity [GO:0019797] 0.887 -0.36085 EIRTRCAR 0 0 0 0 0 0 0 0 0 0 15.2443 0 0 0 0 0 0 0 0 0 0 0 14.4602 0 0 0 0 Q8IVL6 P3H3_HUMAN Prolyl 3-hydroxylase 3 (EC 1.14.11.7) (Leprecan-like protein 2) (Protein B) P3H3 LEPREL2 Homo sapiens (Human) collagen biosynthetic process [GO:0032964]; collagen metabolic process [GO:0032963]; negative regulation of cell population proliferation [GO:0008285]; peptidyl-lysine hydroxylation [GO:0017185] catalytic complex [GO:1902494]; endoplasmic reticulum [GO:0005783] iron ion binding [GO:0005506]; L-ascorbic acid binding [GO:0031418]; procollagen-proline 3-dioxygenase activity [GO:0019797] 0.92384 -0.94754 DLETPPHWAAYDTGLELLGR 0 0 0 0 8.95332 0 0 0 0 0 0 0 0 9.54251 0 0 0 0 7.89591 0 0 0 9.11964 0 0 10.2634 0 Q8IVL8 CBPO_HUMAN Carboxypeptidase O (CPO) (EC 3.4.17.-) CPO Homo sapiens (Human) proteolysis [GO:0006508] apical plasma membrane [GO:0016324]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270] 0.84859 0.11917 IIWMDCGIHAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.23656 0 0 0 0 0 0 0 0 0 Q8IVM0 CCD50_HUMAN Coiled-coil domain-containing protein 50 (Protein Ymer) CCDC50 C3orf6 Homo sapiens (Human) sensory perception of sound [GO:0007605] cytoplasm [GO:0005737]; cytosol [GO:0005829] ubiquitin protein ligase binding [GO:0031625] 0.84159 0.17818 QDPEWKPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.34687 0 0 0 Q8IVM8 S22A9_HUMAN Organic anion transporter 7 (OAT7) (Organic anion/short-chain fatty acid exchanger) (Solute carrier family 22 member 9) SLC22A9 hOAT4 OAT7 UST3 Homo sapiens (Human) hormone transport [GO:0009914]; organic anion transport [GO:0015711]; short-chain fatty acid transmembrane transport [GO:0015913]; sodium-independent organic anion transport [GO:0043252] basolateral plasma membrane [GO:0016323] organic anion transmembrane transporter activity [GO:0008514]; short-chain fatty acid transmembrane transporter activity [GO:0015636]; sodium-independent organic anion transmembrane transporter activity [GO:0015347] 0.4184 0.67641 KPSLCEMLHMPNICKR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.94202 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IVN3 MSTN1_HUMAN Musculoskeletal embryonic nuclear protein 1 MUSTN1 Homo sapiens (Human) chondrocyte differentiation [GO:0002062]; chondrocyte proliferation [GO:0035988]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of gene expression [GO:0010628]; positive regulation of proteoglycan biosynthetic process [GO:1902730]; tissue regeneration [GO:0042246] nucleus [GO:0005634] 0.92057 -0.92266 MSQAGAQEAPIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.40199 0 0 0 0 Q8IVP9 ZN547_HUMAN Zinc finger protein 547 ZNF547 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.84913 0.17174 CGILFMER 0 0 0 0 0 0 0 9.05999 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IVQ6 ZDH21_HUMAN Palmitoyltransferase ZDHHC21 (EC 2.3.1.225) (DHHC domain-containing cysteine-rich protein 21) (DHHC-21) (Zinc finger DHHC domain-containing protein 21) ZDHHC21 Homo sapiens (Human) adrenergic receptor signaling pathway [GO:0071875]; hair follicle development [GO:0001942]; peptidyl-L-cysteine S-palmitoylation [GO:0018230]; protein palmitoylation [GO:0018345]; protein targeting to membrane [GO:0006612]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of leukocyte adhesion to arterial endothelial cell [GO:1904997]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of vascular associated smooth muscle contraction [GO:0003056]; sebaceous gland development [GO:0048733] endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886] palmitoyltransferase activity [GO:0016409]; protein-cysteine S-palmitoyltransferase activity [GO:0019706] 0.88166 -0.31125 SHHCSRCGHCVR 0 0 0 0 0 0 0 0 0 0 9.23321 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IVT2 MISP_HUMAN Mitotic interactor and substrate of PLK1 (Mitotic spindle positioning protein) MISP C19orf21 Homo sapiens (Human) cell division [GO:0051301]; cell migration [GO:0016477]; establishment of centrosome localization [GO:0051660]; establishment of mitotic spindle orientation [GO:0000132]; mitotic spindle assembly [GO:0090307]; organelle localization [GO:0051640]; regulation of protein localization to cell cortex [GO:1904776] actin filament [GO:0005884]; cell cortex [GO:0005938]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; spindle pole centrosome [GO:0031616] actin filament binding [GO:0051015] 0.91824 -0.85475 AATSPKATMSPR 16.5181 16.2579 0 12.9516 13.5016 13.5028 0 16.4698 16.3608 16.1807 16.156 16.4828 9.45865 14.2504 9.28079 0 14.9384 0 13.2663 10.4949 12.9915 12.833 12.2866 12.186 9.49939 14.8488 0 Q8IVT5 KSR1_HUMAN Kinase suppressor of Ras 1 (EC 2.7.11.1) KSR1 KSR Homo sapiens (Human) cAMP-mediated signaling [GO:0019933]; positive regulation of MAPK cascade [GO:0043410]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of cell population proliferation [GO:0042127]; regulation of MAP kinase activity [GO:0043405] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; protein-containing complex [GO:0032991]; ruffle membrane [GO:0032587] 14-3-3 protein binding [GO:0071889]; ATP binding [GO:0005524]; MAP-kinase scaffold activity [GO:0005078]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.95973 -1.9453 AAAMGEK 10.9977 10.9016 10.9574 0 0 0 0 0 0 11.3282 0 10.9627 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IVU3 HERC6_HUMAN Probable E3 ubiquitin-protein ligase HERC6 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 6) (HECT-type E3 ubiquitin transferase HERC6) HERC6 Homo sapiens (Human) hematopoietic progenitor cell differentiation [GO:0002244]; protein ubiquitination [GO:0016567]; response to bacterium [GO:0009617]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654] ubiquitin protein ligase activity [GO:0061630] 0.15332 1.0136 SGQLGYSPTPEKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.43806 9.36056 0 0 0 0 0 0 0 0 0 0 Q8IVV2 LOXH1_HUMAN Lipoxygenase homology domain-containing protein 1 LOXHD1 Homo sapiens (Human) sensory perception of sound [GO:0007605] stereocilium [GO:0032420] 0.96998 -4.3034 AGWFLDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.16546 0 0 0 0 0 0 0 0 0 8.56247 10.1515 10.3351 Q8IVV7 GID4_HUMAN Glucose-induced degradation protein 4 homolog (Vacuolar import and degradation protein 24 homolog) GID4 C17orf39 VID24 Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] ubiquitin ligase complex [GO:0000151] ubiquitin protein ligase activity [GO:0061630] 0.91338 -0.75999 HWGKFLAFYQYAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.45216 0 0 0 0 0 0 Q8IVW6 ARI3B_HUMAN AT-rich interactive domain-containing protein 3B (ARID domain-containing protein 3B) (Bright and dead ringer protein) (Bright-like protein) ARID3B BDP DRIL2 Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677] 0.915 -0.81281 QLPMKIRINGR 0 0 9.38306 9.40886 9.34527 9.29474 10.9929 0 0 10.537 0 10.5901 0 0 0 0 0 0 0 0 0 0 0 0 8.87384 0 0 Q8IW00 VSTM4_HUMAN V-set and transmembrane domain-containing protein 4 [Cleaved into: Peptide Lv] VSTM4 C10orf72 Homo sapiens (Human) endothelial cell migration [GO:0043542]; endothelial cell proliferation [GO:0001935]; retina blood vessel maintenance [GO:0097601]; retina vasculature development in camera-type eye [GO:0061298]; sprouting angiogenesis [GO:0002040]; vasodilation [GO:0042311] extracellular region [GO:0005576]; plasma membrane [GO:0005886] 0.82195 0.21704 GALYRLSVLTLQPSDQGHYVCR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0602 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IW19 APLF_HUMAN Aprataxin and PNK-like factor (EC 3.1.-.-) (Apurinic-apyrimidinic endonuclease APLF) (PNK and APTX-like FHA domain-containing protein) (XRCC1-interacting protein 1) APLF C2orf13 PALF XIP1 Homo sapiens (Human) DNA damage response [GO:0006974]; DNA repair [GO:0006281]; DNA repair-dependent chromatin remodeling [GO:0140861]; double-strand break repair [GO:0006302]; double-strand break repair via nonhomologous end joining [GO:0006303]; embryo implantation [GO:0007566]; positive regulation of DNA ligation [GO:0051106]; protein localization to chromatin [GO:0071168]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of isotype switching [GO:0045191]; single strand break repair [GO:0000012] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861] 3'-5' exonuclease activity [GO:0008408]; ADP-D-ribose modification-dependent protein binding [GO:0160002]; DNA endonuclease activity [GO:0004520]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; histone binding [GO:0042393]; histone chaperone activity [GO:0140713]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; poly-ADP-D-ribose binding [GO:0072572]; protein folding chaperone [GO:0044183] 0.55723 0.54435 GPLLGITDK 0 0 0 0 0 0 0 9.59182 9.39738 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IW36 ZN695_HUMAN Zinc finger protein 695 (Zinc finger protein SBZF3) ZNF695 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.89824 -0.66814 AFGQSSHLSK 14.1979 0 0 0 0 0 0 0 9.04045 0 0 0 0 0 0 9.14776 0 0 0 0 0 0 0 0 0 0 0 Q8IW40 CC103_HUMAN Coiled-coil domain-containing protein 103 CCDC103 Homo sapiens (Human) axonemal dynein complex assembly [GO:0070286]; cilium movement [GO:0003341]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; heart looping [GO:0001947]; inner dynein arm assembly [GO:0036159]; outer dynein arm assembly [GO:0036158] axoneme [GO:0005930]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; motile cilium [GO:0031514]; outer dynein arm [GO:0036157] protein homodimerization activity [GO:0042803] 0.84197 0.18284 TFQDVATEISPEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.13283 Q8IW41 MAPK5_HUMAN MAP kinase-activated protein kinase 5 (MAPK-activated protein kinase 5) (MAPKAP kinase 5) (MAPKAP-K5) (MAPKAPK-5) (MK-5) (MK5) (EC 2.7.11.1) (p38-regulated/activated protein kinase) (PRAK) MAPKAPK5 PRAK Homo sapiens (Human) cellular senescence [GO:0090398]; negative regulation of TOR signaling [GO:0032007]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein autophosphorylation [GO:0046777]; Ras protein signal transduction [GO:0007265]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of translation [GO:0006417]; signal transduction [GO:0007165]; stress-induced premature senescence [GO:0090400] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; septin cytoskeleton [GO:0032156] ATP binding [GO:0005524]; calcium-dependent protein serine/threonine kinase activity [GO:0009931]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; MAP kinase kinase activity [GO:0004708]; mitogen-activated protein kinase binding [GO:0051019]; p53 binding [GO:0002039]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.95169 -1.4285 GENEDEKLNEVMQEAWKYNR 0 0 0 0 8.97218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IW50 F219A_HUMAN Protein FAM219A FAM219A C9orf25 Homo sapiens (Human) 0.92716 -1.2058 KNNVMARTR 10.2994 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IW52 SLIK4_HUMAN SLIT and NTRK-like protein 4 SLITRK4 Homo sapiens (Human) axonogenesis [GO:0007409]; positive regulation of synapse assembly [GO:0051965]; regulation of presynapse assembly [GO:1905606]; regulation of synapse organization [GO:0050807] glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886] 0.96567 -2.3615 DLLHVDTRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.476 0 0 0 0 Q8IW93 ARHGJ_HUMAN Rho guanine nucleotide exchange factor 19 (Ephexin-2) ARHGEF19 Homo sapiens (Human) "activation of GTPase activity [GO:0090630]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of small GTPase mediated signal transduction [GO:0051056]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing [GO:0042060]" cytosol [GO:0005829] GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085] 0.92039 -0.91618 ENKRVTSATSK 0 0 0 0 0 0 0 0 0 0 13.6405 0 0 0 9.93158 0 0 0 0 0 0 0 0 0 0 0 0 Q8IWA0 WDR75_HUMAN WD repeat-containing protein 75 (U3 small nucleolar RNA-associated protein 17 homolog) WDR75 UTP17 Homo sapiens (Human) positive regulation of rRNA processing [GO:2000234]; positive regulation of transcription by RNA polymerase I [GO:0045943]; ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364] nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040] RNA binding [GO:0003723] 0.96973 -4.0441 DATEKNK 11.3127 0 0 0 0 0 0 0 11.5325 0 0 0 0 10.1435 0 0 0 0 0 0 9.84409 8.76045 0 0 0 0 9.46989 Q8IWA4 MFN1_HUMAN Mitofusin-1 (EC 3.6.5.-) (Fzo homolog) (Transmembrane GTPase MFN1) MFN1 Homo sapiens (Human) GTP metabolic process [GO:0046039]; mitochondrial fusion [GO:0008053]; mitochondrion localization [GO:0051646]; positive regulation of mitochondrial membrane potential [GO:0010918] membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; outer mitochondrial membrane protein complex [GO:0098799] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802] 0.91834 -0.8809 HIEDGMGRNLADR 0 8.70224 0 0 0 0 0 0 9.88646 0 0 0 0 0 9.83211 0 0 0 0 0 0 0 0 0 10.3874 10.1983 0 Q8IWA5 CTL2_HUMAN Choline transporter-like protein 2 (Solute carrier family 44 member 2) SLC44A2 CTL2 PSEC0210 Homo sapiens (Human) choline transport [GO:0015871]; ethanolamine transport [GO:0034229]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; transmembrane transport [GO:0055085] extracellular exosome [GO:0070062]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579] choline transmembrane transporter activity [GO:0015220]; ethanolamine transmembrane transporter activity [GO:0034228] 0.96187 -2.0385 NAFFLLMRNIIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.97269 0 Q8IWB6 TEX14_HUMAN Inactive serine/threonine-protein kinase TEX14 (Protein kinase-like protein SgK307) (Sugen kinase 307) (Testis-expressed sequence 14) (Testis-expressed sequence 14 protein) TEX14 SGK307 Homo sapiens (Human) attachment of spindle microtubules to kinetochore [GO:0008608]; cell division [GO:0051301]; cellular response to leukemia inhibitory factor [GO:1990830]; intercellular bridge organization [GO:0043063]; male meiotic nuclear division [GO:0007140]; mitotic sister chromatid separation [GO:0051306]; mitotic spindle assembly checkpoint signaling [GO:0007094]; negative regulation of cytokinesis [GO:0032466]; negative regulation of protein binding [GO:0032091]; protein phosphorylation [GO:0006468] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; kinetochore [GO:0000776]; midbody [GO:0030496] ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901] 0.84205 0.148 EDSITPERR 0 0 0 0 0 0 0 0 0 0 9.79149 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IWB9 TEX2_HUMAN Testis-expressed protein 2 (Transmembrane protein 96) TEX2 KIAA1738 TMEM96 Homo sapiens (Human) lipid transport [GO:0006869]; signal transduction [GO:0007165]; sphingolipid metabolic process [GO:0006665] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; nuclear membrane [GO:0031965] lipid binding [GO:0008289] 0.96992 -3.0827 IEDTKRR 9.94748 8.61776 0 0 0 0 10.4442 0 0 0 0 0 0 10.2675 0 0 0 0 0 9.36251 0 0 0 0 0 0 0 Q8IWC1 MA7D3_HUMAN MAP7 domain-containing protein 3 MAP7D3 MDP3 Homo sapiens (Human) microtubule cytoskeleton organization [GO:0000226]; microtubule polymerization [GO:0046785] cytoplasm [GO:0005737]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; spindle [GO:0005819] microtubule binding [GO:0008017]; tubulin binding [GO:0015631] 0.96931 -3.574 LAREQREK 0 0 0 0 0 0 9.48208 0 0 9.57395 0 0 0 0 0 9.50855 0 0 0 0 0 0 0 0 0 0 0 Q8IWD4 CC117_HUMAN Coiled-coil domain-containing protein 117 CCDC117 Homo sapiens (Human) positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA repair [GO:0045739] cytoplasm [GO:0005737]; mitotic spindle [GO:0072686]; nucleus [GO:0005634] 0.92359 -1.0468 VSVHCKKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.14034 0 0 0 0 0 Q8IWD5 MFS6L_HUMAN Major facilitator superfamily domain-containing protein 6-like MFSD6L FP7072 Homo sapiens (Human) membrane [GO:0016020] 0.91595 -0.77178 ALGVAKLFHLVCGVR 0 0 0 0 0 0 0 18.12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IWE5 PKHM2_HUMAN Pleckstrin homology domain-containing family M member 2 (PH domain-containing family M member 2) (Salmonella-induced filaments A and kinesin-interacting protein) (SifA and kinesin-interacting protein) PLEKHM2 KIAA0842 SKIP Homo sapiens (Human) Golgi organization [GO:0007030]; lysosome localization [GO:0032418]; natural killer cell mediated cytotoxicity [GO:0042267]; regulation of protein localization [GO:0032880] endosome membrane [GO:0010008]; lysosomal membrane [GO:0005765] kinesin binding [GO:0019894] 0.96711 -3.7048 LVCTNRR 0 0 0 0 11.4646 0 0 0 8.32134 0 0 12.6813 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IWF6 DEN6A_HUMAN Protein DENND6A (DENN domain-containing protein 6A) DENND6A FAM116A Homo sapiens (Human) positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049] cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; recycling endosome [GO:0055037] guanyl-nucleotide exchange factor activity [GO:0005085] 0.36659 0.74191 NEPYLEAACNDVDRWPAPVPGK 0 0 0 0 0 0 0 10.1546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IWF9 CCD83_HUMAN Coiled-coil domain-containing protein 83 CCDC83 HSD9 Homo sapiens (Human) 0.95524 -1.5559 HLLKELSEEK 0 0 0 0 0 0 0 0 0 13.127 0 13.0511 0 8.59343 0 0 0 0 0 0 0 0 0 0 0 0 12.7096 Q8IWG1 DNAI3_HUMAN Dynein axonemal intermediate chain 3 (Testis development protein NYD-SP29) (WD repeat-containing protein 63) DNAI3 WDR63 Homo sapiens (Human) cilium movement involved in cell motility [GO:0060294]; inner dynein arm assembly [GO:0036159]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; negative regulation of cell migration [GO:0030336]; positive regulation of osteoblast differentiation [GO:0045669] axonemal dynein complex [GO:0005858]; cytoplasm [GO:0005737]; inner dynein arm [GO:0036156] Arp2/3 complex binding [GO:0071933]; dynein heavy chain binding [GO:0045504]; dynein light chain binding [GO:0045503] 0.95578 -1.595 AGGSRSK 0 0 0 0 9.54458 9.20579 0 9.2662 0 9.63813 9.13594 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IWI9 MGAP_HUMAN MAX gene-associated protein (MAX dimerization protein 5) MGA KIAA0518 MAD5 Homo sapiens (Human) cell fate specification [GO:0001708]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; MLL1 complex [GO:0071339]; nucleoplasm [GO:0005654] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein dimerization activity [GO:0046983]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.9691 -7.0505 EKECGDSLEK 11.4718 0 10.269 0 0 0 0 0 0 0 0 9.1443 9.26315 13.1441 0 13.4921 11.0395 11.5937 9.76703 0 0 9.40678 9.10609 12.0095 10.8422 0 12.7226 Q8IWJ2 GCC2_HUMAN GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) (GCC185) (CLL-associated antigen KW-11) (CTCL tumor antigen se1-1) (Ran-binding protein 2-like 4) (RanBP2L4) (Renal carcinoma antigen NY-REN-53) GCC2 KIAA0336 RANBP2L4 Homo sapiens (Human) "Golgi ribbon formation [GO:0090161]; late endosome to Golgi transport [GO:0034499]; microtubule anchoring [GO:0034453]; microtubule organizing center organization [GO:0031023]; protein localization to Golgi apparatus [GO:0034067]; protein targeting to lysosome [GO:0006622]; recycling endosome to Golgi transport [GO:0071955]; regulation of protein exit from endoplasmic reticulum [GO:0070861]; retrograde transport, endosome to Golgi [GO:0042147]" cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; trans-Golgi network [GO:0005802] identical protein binding [GO:0042802]; small GTPase binding [GO:0031267] 0.96884 -8.4944 AKSRCTELEK 9.63699 0 9.20016 0 8.61434 0 9.76175 0 0 0 0 0 0 9.66383 9.74488 9.51804 9.05287 10.3147 0 0 0 0 0 9.7751 0 9.92391 0 Q8IWK6 AGRA3_HUMAN Adhesion G protein-coupled receptor A3 (G-protein coupled receptor 125) ADGRA3 GPR125 UNQ556/PRO1113 Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] external side of plasma membrane [GO:0009897]; membrane [GO:0016020]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930] 0.96933 -3.2146 GDFRWPR 0 0 0 0 0 0 0 0 0 0 0 0 8.95169 0 0 0 9.16644 0 0 0 0 0 0 0 0 0 0 Q8IWL2 SFTA1_HUMAN Pulmonary surfactant-associated protein A1 (PSP-A) (PSPA) (SP-A) (SP-A1) (35 kDa pulmonary surfactant-associated protein) (Alveolar proteinosis protein) (Collectin-4) SFTPA1 COLEC4 PSAP SFTP1 SFTPA SFTPA1B Homo sapiens (Human) opsonization [GO:0008228]; respiratory gaseous exchange by respiratory system [GO:0007585] clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lamellar body [GO:0042599]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791] carbohydrate binding [GO:0030246]; lipid transporter activity [GO:0005319] 0.34956 0.76741 KYNTYAYVGLTEGPSPGDFR 0 0 0 0 0 0 0 0 10.0253 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IWL3 HSC20_HUMAN "Iron-sulfur cluster co-chaperone protein HscB (DnaJ homolog subfamily C member 20) [Cleaved into: Iron-sulfur cluster co-chaperone protein HscB, cytoplasmic (C-HSC20); Iron-sulfur cluster co-chaperone protein HscB, mitochondrial]" HSCB DNAJC20 HSC20 Homo sapiens (Human) [2Fe-2S] cluster assembly [GO:0044571]; iron-sulfur cluster assembly [GO:0016226]; primitive erythrocyte differentiation [GO:0060319]; primitive hemopoiesis [GO:0060215]; protein complex oligomerization [GO:0051259] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] ATPase activator activity [GO:0001671]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein-folding chaperone binding [GO:0051087] 0.82158 0.21759 CWNCGGPWGPGR 0 0 0 0 0 0 0 0 0 0 0 0 0 14.2088 0 0 0 0 0 0 12.7332 12.2241 12.2866 0 0 0 0 Q8IWN7 RP1L1_HUMAN Retinitis pigmentosa 1-like 1 protein RP1L1 Homo sapiens (Human) axoneme assembly [GO:0035082]; intracellular signal transduction [GO:0035556]; photoreceptor cell development [GO:0042461]; photoreceptor cell maintenance [GO:0045494]; retina development in camera-type eye [GO:0060041]; visual perception [GO:0007601] axoneme [GO:0005930]; microtubule [GO:0005874]; photoreceptor connecting cilium [GO:0032391]; photoreceptor outer segment [GO:0001750] 0.96885 -7.6161 EAPAGCR 10.1841 0 0 0 0 0 10.033 0 0 9.78922 0 8.38767 0 0 0 10.8167 9.87587 0 0 0 0 0 0 0 0 0 0 Q8IWP9 CC28A_HUMAN Coiled-coil domain-containing protein 28A (CCRL1AP) CCDC28A C6orf80 Homo sapiens (Human) 0.94889 -1.3753 SWPWCNKELKTMEER 0 0 0 0 0 0 0 0 0 0 0 0 10.3487 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IWQ3 BRSK2_HUMAN Serine/threonine-protein kinase BRSK2 (EC 2.7.11.1) (Brain-selective kinase 2) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 2) (BR serine/threonine-protein kinase 2) (Serine/threonine-protein kinase 29) (Serine/threonine-protein kinase SAD-A) BRSK2 C11orf7 PEN11B SADA STK29 HUSSY-12 Homo sapiens (Human) "actin cytoskeleton reorganization [GO:0031532]; axonogenesis [GO:0007409]; cell division [GO:0051301]; ERAD pathway [GO:0036503]; establishment of cell polarity [GO:0030010]; exocytosis [GO:0006887]; G2/M transition of mitotic cell cycle [GO:0000086]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; neuron differentiation [GO:0030182]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]; regulation of ATP-dependent activity [GO:0043462]; regulation of axonogenesis [GO:0050770]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; regulation of neuron projection development [GO:0010975]; regulation of retrograde protein transport, ER to cytosol [GO:1904152]; regulation of synaptic vesicle clustering [GO:2000807]" centrosome [GO:0005813]; cytoplasm [GO:0005737]; distal axon [GO:0150034]; endoplasmic reticulum [GO:0005783]; perinuclear region of cytoplasm [GO:0048471] ATP binding [GO:0005524]; ATPase binding [GO:0051117]; ATPase regulator activity [GO:0060590]; magnesium ion binding [GO:0000287]; protein kinase binding [GO:0019901]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321] 0.91494 -0.81479 AIEMAQHGQR 0 0 0 0 10.241 9.94575 9.49572 0 0 0 11.3787 0 0 0 10.2949 0 0 0 9.33646 0 0 0 0 0 0 0 0 Q8IWR0 Z3H7A_HUMAN Zinc finger CCCH domain-containing protein 7A ZC3H7A ZC3H7 ZC3HDC7 HSPC055 Homo sapiens (Human) miRNA processing [GO:0035196]; post-transcriptional regulation of gene expression [GO:0010608] nucleus [GO:0005634] metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; RNA binding [GO:0003723] 0.81625 0.22087 LTQELAQK 0 0 0 0 0 0 0 0 0 0 0 0 8.56003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IWT1 SCN4B_HUMAN Sodium channel subunit beta-4 SCN4B Homo sapiens (Human) AV node cell action potential [GO:0086016]; cardiac muscle cell action potential involved in contraction [GO:0086002]; cardiac muscle contraction [GO:0060048]; establishment of localization in cell [GO:0051649]; membrane depolarization during cardiac muscle cell action potential [GO:0086012]; positive regulation of sodium ion transport [GO:0010765]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of sodium ion transmembrane transporter activity [GO:2000649]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] intercalated disc [GO:0014704]; plasma membrane [GO:0005886]; voltage-gated sodium channel complex [GO:0001518] sodium channel regulator activity [GO:0017080]; transmembrane transporter binding [GO:0044325]; voltage-gated monoatomic ion channel activity [GO:0005244]; voltage-gated sodium channel activity [GO:0005248]; voltage-gated sodium channel activity involved in cardiac muscle cell action potential [GO:0086006] 0.71336 0.36718 LIIFILK 0 0 0 0 0 0 0 0 0 0 9.04059 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IWT3 CUL9_HUMAN Cullin-9 (CUL-9) (UbcH7-associated protein 1) (p53-associated parkin-like cytoplasmic protein) CUL9 H7AP1 KIAA0708 PARC Homo sapiens (Human) microtubule cytoskeleton organization [GO:0000226]; protein ubiquitination [GO:0016567]; regulation of mitotic nuclear division [GO:0007088]; ubiquitin-dependent protein catabolic process [GO:0006511] cullin-RING ubiquitin ligase complex [GO:0031461]; cytosol [GO:0005829] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625] 0.84192 0.14238 ADCLSTGMELLRR 9.80649 0 0 0 0 0 0 0 9.03969 0 0 0 0 10.6348 8.98453 0 0 0 0 10.3512 0 9.32186 9.39767 0 0 0 0 Q8IWU5 SULF2_HUMAN Extracellular sulfatase Sulf-2 (hSulf-2) (Arylsulfatase) (EC 3.1.6.1) (N-acetylglucosamine-6-sulfatase) (EC 3.1.6.14) [Cleaved into: Extracellular sulfatase Sulf-2 secreted form] SULF2 KIAA1247 UNQ559/PRO1120 Homo sapiens (Human) bone development [GO:0060348]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; embryonic skeletal system development [GO:0048706]; esophagus smooth muscle contraction [GO:0014846]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; glomerular basement membrane development [GO:0032836]; glomerular filtration [GO:0003094]; heparan sulfate proteoglycan metabolic process [GO:0030201]; innervation [GO:0060384]; kidney development [GO:0001822]; liver regeneration [GO:0097421]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of hepatocyte proliferation [GO:2000345]; response to wounding [GO:0009611] cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi stack [GO:0005795]; plasma membrane [GO:0005886] arylsulfatase activity [GO:0004065]; calcium ion binding [GO:0005509]; glycosaminoglycan binding [GO:0005539]; N-acetylglucosamine-6-sulfatase activity [GO:0008449] 0.88277 -0.070844 GPMRLGGSR 10.05 13.1669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IWU6 SULF1_HUMAN Extracellular sulfatase Sulf-1 (hSulf-1) (Arylsulfatase) (EC 3.1.6.1) (N-acetylglucosamine-6-sulfatase) (EC 3.1.6.14) [Cleaved into: Extracellular sulfatase Sulf-2 secreted form] SULF1 KIAA1077 Homo sapiens (Human) apoptotic process [GO:0006915]; bone development [GO:0060348]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; embryonic skeletal system development [GO:0048706]; esophagus smooth muscle contraction [GO:0014846]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; glomerular basement membrane development [GO:0032836]; glomerular filtration [GO:0003094]; heparan sulfate proteoglycan metabolic process [GO:0030201]; innervation [GO:0060384]; kidney development [GO:0001822]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell migration [GO:0030336]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of prostatic bud formation [GO:0060686]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of fibroblast growth factor receptor signaling pathway [GO:0040036]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi stack [GO:0005795]; membrane raft [GO:0045121]; plasma membrane [GO:0005886] arylsulfatase activity [GO:0004065]; calcium ion binding [GO:0005509]; glycosaminoglycan binding [GO:0005539]; N-acetylglucosamine-6-sulfatase activity [GO:0008449] 0.95575 -1.5477 ESGYRASR 10.0056 10.1174 10.3172 0 0 0 9.66812 0 11.0877 9.27524 0 0 0 0 0 0 0 0 0 0 8.99625 0 9.35421 0 0 0 0 Q8IWU9 TPH2_HUMAN Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Neuronal tryptophan hydroxylase) (Tryptophan 5-monooxygenase 2) TPH2 NTPH Homo sapiens (Human) aromatic amino acid metabolic process [GO:0009072]; cellular response to lithium ion [GO:0071285]; circadian rhythm [GO:0007623]; response to activity [GO:0014823]; response to calcium ion [GO:0051592]; response to estrogen [GO:0043627]; response to glucocorticoid [GO:0051384]; response to nutrient levels [GO:0031667]; serotonin biosynthetic process [GO:0042427] cytosol [GO:0005829]; neuron projection [GO:0043005] iron ion binding [GO:0005506]; tryptophan 5-monooxygenase activity [GO:0004510] 0.8841 -0.17349 TWGVVFRELSK 0 0 0 0 9.23043 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IWV2 CNTN4_HUMAN Contactin-4 (Brain-derived immunoglobulin superfamily protein 2) (BIG-2) CNTN4 Homo sapiens (Human) axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; axonogenesis [GO:0007409]; brain development [GO:0007420]; dendrite self-avoidance [GO:0070593]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of neuron differentiation [GO:0045665]; nervous system development [GO:0007399]; neuron cell-cell adhesion [GO:0007158]; neuron projection development [GO:0031175]; regulation of synaptic plasticity [GO:0048167] axon [GO:0030424]; extracellular region [GO:0005576]; plasma membrane [GO:0005886] cell-cell adhesion mediator activity [GO:0098632] 0.72511 0.3474 LSAAADLIVR 0 0 0 0 0 0 0 0 0 0 10.2794 0 0 0 0 0 11.474 0 0 0 0 0 0 0 12.1461 0 9.9516 Q8IWV7 UBR1_HUMAN E3 ubiquitin-protein ligase UBR1 (EC 2.3.2.27) (N-recognin-1) (RING-type E3 ubiquitin transferase UBR1) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3-alpha-I) UBR1 Homo sapiens (Human) cellular response to leucine [GO:0071233]; negative regulation of TOR signaling [GO:0032007]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596] cytoplasm [GO:0005737]; cytosol [GO:0005829]; proteasome complex [GO:0000502]; ubiquitin ligase complex [GO:0000151] leucine binding [GO:0070728]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.96822 -2.7777 AEAARLHR 9.99081 0 9.95841 0 0 0 0 0 9.93908 0 0 0 0 10.6365 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IWV8 UBR2_HUMAN E3 ubiquitin-protein ligase UBR2 (EC 2.3.2.27) (N-recognin-2) (RING-type E3 ubiquitin transferase UBR2) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3-alpha-II) UBR2 C6orf133 KIAA0349 Homo sapiens (Human) cellular response to leucine [GO:0071233]; heterochromatin formation [GO:0031507]; histone H2A ubiquitination [GO:0033522]; male meiosis I [GO:0007141]; male meiotic nuclear division [GO:0007140]; negative regulation of TOR signaling [GO:0032007]; reciprocal meiotic recombination [GO:0007131]; retrotransposon silencing [GO:0010526]; spermatogenesis [GO:0007283]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151] histone ubiquitin ligase activity [GO:0140852]; leucine binding [GO:0070728]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.8855 -0.36813 ETGMESVIEAVAHFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5173 Q8IWW6 RHG12_HUMAN Rho GTPase-activating protein 12 (Rho-type GTPase-activating protein 12) ARHGAP12 Homo sapiens (Human) "actin filament organization [GO:0007015]; morphogenesis of an epithelial sheet [GO:0002011]; negative regulation of small GTPase mediated signal transduction [GO:0051058]; phagocytosis, engulfment [GO:0006911]; regulation of GTPase activity [GO:0043087]; signal transduction [GO:0007165]" cytoplasm [GO:0005737]; phagocytic cup [GO:0001891] GTPase activator activity [GO:0005096] 0.84737 0.15668 ALMPPVK 8.68717 0 0 0 0 0 0 0 0 9.19522 0 9.22183 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IWW8 HOT_HUMAN "Hydroxyacid-oxoacid transhydrogenase, mitochondrial (HOT) (EC 1.1.99.24) (Alcohol dehydrogenase iron-containing protein 1) (ADHFe1) (Fe-containing alcohol dehydrogenase)" ADHFE1 HMFT2263 Homo sapiens (Human) 2-oxoglutarate metabolic process [GO:0006103]; glutamate catabolic process via 2-oxoglutarate [GO:0006539]; lipid metabolic process [GO:0006629] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] alcohol dehydrogenase (NAD+) activity [GO:0004022]; hydroxyacid-oxoacid transhydrogenase activity [GO:0047988]; metal ion binding [GO:0046872] 0.84607 0.17326 NVCLMTDK 0 0 0 0 10.0577 9.93951 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IWX5 SGPP2_HUMAN Sphingosine-1-phosphate phosphatase 2 (SPPase2) (Spp2) (hSPP2) (EC 3.1.3.-) (Sphingosine-1-phosphatase 2) SGPP2 Homo sapiens (Human) phospholipid dephosphorylation [GO:0046839]; regulation of type B pancreatic cell proliferation [GO:0061469]; sphingolipid biosynthetic process [GO:0030148]; sphingosine metabolic process [GO:0006670] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789] dihydrosphingosine-1-phosphate phosphatase activity [GO:0070780]; sphingosine-1-phosphate phosphatase activity [GO:0042392] 0.93216 -1.2866 VVTRNKEAR 0 0 11.7775 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IWX7 UN45B_HUMAN Protein unc-45 homolog B (Unc-45B) (SMUNC45) UNC45B CMYA4 UNC45 Homo sapiens (Human) cell differentiation [GO:0030154]; chaperone-mediated protein folding [GO:0061077]; lens development in camera-type eye [GO:0002088]; muscle organ development [GO:0007517] A band [GO:0031672]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]; Z disc [GO:0030018] Hsp90 protein binding [GO:0051879] 0.86996 0.047565 CQALEHLGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.36639 0 0 0 0 Q8IWX8 CHERP_HUMAN Calcium homeostasis endoplasmic reticulum protein (ERPROT 213-21) (SR-related CTD-associated factor 6) CHERP DAN26 SCAF6 Homo sapiens (Human) intracellular calcium ion homeostasis [GO:0006874]; negative regulation of cell population proliferation [GO:0008285]; nervous system development [GO:0007399]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; release of sequestered calcium ion into cytosol [GO:0051209]; RNA processing [GO:0006396] cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; sarcoplasmic reticulum membrane [GO:0033017] RNA binding [GO:0003723]; transmembrane transporter binding [GO:0044325] 0.60804 0.43087 GQEKRNSGPSR 0 0 0 0 0 7.81372 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IWY4 SCUB1_HUMAN "Signal peptide, CUB and EGF-like domain-containing protein 1" SCUBE1 Homo sapiens (Human) adult heart development [GO:0007512]; blood coagulation [GO:0007596]; endothelial cell differentiation [GO:0045446]; inflammatory response [GO:0006954]; positive regulation of smoothened signaling pathway [GO:0045880]; post-embryonic development [GO:0009791]; signal transduction [GO:0007165] cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; identical protein binding [GO:0042802] 0.88092 0.0071747 CLCKPGYKGEGK 8.32957 0 0 0 0 0 0 0 0 10.169 10.3866 10.4359 0 0 8.90767 0 0 0 0 0 0 0 0 0 0 0 0 Q8IWY8 ZSC29_HUMAN Zinc finger and SCAN domain-containing protein 29 (Zinc finger protein 690) ZSCAN29 ZNF690 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96929 -7.3004 CLDCGKSFRDSSNFITHR 0 0 0 0 0 0 0 0 0 11.1171 0 0 9.71697 0 0 11.6169 0 10.5232 0 0 0 0 0 9.6969 0 0 0 Q8IWY9 CDAN1_HUMAN Codanin-1 CDAN1 UNQ664/PRO1295 Homo sapiens (Human) chromatin organization [GO:0006325]; import into nucleus [GO:0051170]; protein localization [GO:0008104] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; nucleus [GO:0005634]; plasma membrane [GO:0005886] 0.92305 -1.1544 LLASWVSGSSGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1932 8.61637 0 0 0 0 0 Q8IWZ3 ANKH1_HUMAN Ankyrin repeat and KH domain-containing protein 1 (HIV-1 Vpr-binding ankyrin repeat protein) (Multiple ankyrin repeats single KH domain) (hMASK) ANKHD1 KIAA1085 MASK VBARP PP2500 Homo sapiens (Human) innate immune response [GO:0045087] cytoplasm [GO:0005737] RNA binding [GO:0003723] 0.95958 -1.8836 AGHLCTVQFLISK 0 0 0 9.79589 10.2857 9.52546 0 0 0 8.40574 0 0 9.98314 9.93151 9.77693 0 10.519 0 0 0 0 0 0 9.981 0 0 10.016 Q8IWZ4 TRI48_HUMAN E3 ubiquitin-protein ligase TRIM48 (EC 2.3.2.27) (RING finger protein 101) (Tripartite motif-containing protein 48) TRIM48 RNF101 Homo sapiens (Human) innate immune response [GO:0045087]; protein ubiquitination [GO:0016567]; regulation of gene expression [GO:0010468] cytoplasm [GO:0005737]; cytosol [GO:0005829] ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.84572 0.15386 HCPAEWAAEEHWEK 0 0 0 0 0 0 0 0 0 10.1667 9.92465 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IWZ5 TRI42_HUMAN Tripartite motif-containing protein 42 TRIM42 Homo sapiens (Human) cellular anatomical entity [GO:0110165] zinc ion binding [GO:0008270] 0.96796 -2.8773 AKVGLEACGR 0 0 0 9.70743 0 9.65516 10.6402 10.7791 0 0 0 0 0 10.9931 0 0 0 0 0 0 9.82531 0 0 0 0 0 0 Q8IX04 UEVLD_HUMAN Ubiquitin-conjugating enzyme E2 variant 3 (UEV-3) (EV and lactate/malate dehydrogenase domain-containing protein) UEVLD UEV3 Homo sapiens (Human) carboxylic acid metabolic process [GO:0019752]; endosome to lysosome transport [GO:0008333]; protein modification process [GO:0036211]; protein transport [GO:0015031] ESCRT I complex [GO:0000813]; extracellular exosome [GO:0070062] "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; ubiquitin binding [GO:0043130]" 0.95006 -1.3838 LSTFPANR 0 0 0 0 0 0 0 0 0 0 0 0 9.78555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IX07 FOG1_HUMAN Zinc finger protein ZFPM1 (Friend of GATA protein 1) (FOG-1) (Friend of GATA 1) (Zinc finger protein 89A) (Zinc finger protein multitype 1) ZFPM1 FOG1 ZFN89A Homo sapiens (Human) atrial septum morphogenesis [GO:0060413]; atrioventricular valve morphogenesis [GO:0003181]; cardiac muscle tissue morphogenesis [GO:0055008]; definitive erythrocyte differentiation [GO:0060318]; embryonic hemopoiesis [GO:0035162]; erythrocyte differentiation [GO:0030218]; granulocyte differentiation [GO:0030851]; heart development [GO:0007507]; megakaryocyte development [GO:0035855]; megakaryocyte differentiation [GO:0030219]; mitral valve formation [GO:0003192]; negative regulation of interleukin-4 production [GO:0032713]; negative regulation of mast cell differentiation [GO:0060377]; negative regulation of protein binding [GO:0032091]; negative regulation of transcription by RNA polymerase II [GO:0000122]; outflow tract morphogenesis [GO:0003151]; platelet formation [GO:0030220]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type II interferon production [GO:0032729]; primitive erythrocyte differentiation [GO:0060319]; regulation of chemokine production [GO:0032642]; regulation of definitive erythrocyte differentiation [GO:0010724]; T-helper cell lineage commitment [GO:0002295]; tricuspid valve formation [GO:0003195]; ventricular septum morphogenesis [GO:0060412] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667]; transcription repressor complex [GO:0017053] DNA binding [GO:0003677]; metal ion binding [GO:0046872]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription corepressor activity [GO:0003714] 0.89831 -0.59653 APPGPAR 13.8603 13.8741 13.2913 0 10.0916 0 12.6481 12.7265 12.731 9.65616 0 10.3185 0 0 0 9.83028 0 0 0 0 0 0 0 0 0 0 0 Q8IX12 CCAR1_HUMAN Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain) CCAR1 CARP1 DIS Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] nuclear envelope lumen [GO:0005641]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] nuclear receptor coactivator activity [GO:0030374]; RNA binding [GO:0003723]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase activity [GO:0061630] 0.69758 0.37895 DGFQHPAR 11.3853 0 0 0 0 0 0 0 0 0 0 0 9.36988 0 0 0 10.5704 0 0 0 0 0 0 0 0 0 0 Q8IX18 DHX40_HUMAN Probable ATP-dependent RNA helicase DHX40 (EC 3.6.4.13) (DEAH box protein 40) (Protein PAD) DHX40 DDX40 ARG147 Homo sapiens (Human) ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; helicase activity [GO:0004386]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.96878 -6.5564 CFRIYSK 0 0 0 0 0 0 0 0 0 8.72072 0 0 0 12.5307 0 10.1169 0 0 0 0 10.218 0 0 0 0 0 0 Q8IX21 SLF2_HUMAN SMC5-SMC6 complex localization factor protein 2 (Smc5/6 localization factor 1) SLF2 C10orf6 FAM178A Homo sapiens (Human) DNA damage response [GO:0006974]; double-strand break repair via homologous recombination [GO:0000724]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of protein-containing complex assembly [GO:0031334]; protein localization to site of double-strand break [GO:1990166]; protein sumoylation [GO:0016925]; regulation of telomere maintenance [GO:0032204] "chromatin [GO:0000785]; chromosome, telomeric region [GO:0000781]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]; Smc5-Smc6 complex [GO:0030915]" protein-containing complex binding [GO:0044877]; ubiquitin protein ligase binding [GO:0031625] 0.81065 0.22563 SLFIHENNEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.75912 0 0 0 0 10.4501 0 0 Q8IX29 FBX16_HUMAN F-box only protein 16 FBXO16 FBX16 Homo sapiens (Human) 0.94073 -1.3282 KAQSMMSRR 0 0 0 0 0 0 0 0 0 0 0 0 8.74029 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IX30 SCUB3_HUMAN "Signal peptide, CUB and EGF-like domain-containing protein 3" SCUBE3 CEGF3 Homo sapiens (Human) positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of osteoblast differentiation [GO:0045669]; signal transduction [GO:0007165] cell surface [GO:0009986]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] BMP binding [GO:0036122]; BMP receptor binding [GO:0070700]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802] 0.89762 -0.53461 DTCALTCPSR 0 0 0 0 9.67389 0 0 0 8.7199 0 0 0 0 9.46091 0 0 0 11.5643 0 0 0 0 0 0 0 0 0 Q8IX90 SKA3_HUMAN Spindle and kinetochore-associated protein 3 SKA3 C13orf3 RAMA1 Homo sapiens (Human) cell division [GO:0051301]; chromosome segregation [GO:0007059]; mitotic cell cycle [GO:0000278]; regulation of microtubule polymerization or depolymerization [GO:0031110] centrosome [GO:0005813]; cytosol [GO:0005829]; kinetochore [GO:0000776]; mitotic spindle [GO:0072686]; outer kinetochore [GO:0000940]; spindle microtubule [GO:0005876] 0.93261 -1.2766 AVPPSKRFLK 0 0 0 0 0 10.5493 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IX94 CTGE4_HUMAN cTAGE family member 4 (Protein cTAGE-4) CTAGE4 Homo sapiens (Human) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein secretion [GO:0009306]; vesicle cargo loading [GO:0035459] endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789] 0.91655 -0.83652 ATEGLETYR 0 0 0 0 0 0 0 0 0 0 0 9.71292 10.1566 9.21021 0 0 0 11.1573 0 0 9.19133 0 0 0 0 0 0 Q8IX95 CTGE3_HUMAN Putative cTAGE family member 3 (Protein cTAGE-3) CTAGE3P CTAGE3 Homo sapiens (Human) 0.80804 0.23075 LNASLTTLEGER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.93356 0 0 0 0 0 Q8IXB1 DJC10_HUMAN DnaJ homolog subfamily C member 10 (EC 1.8.4.-) (Endoplasmic reticulum DNA J domain-containing protein 5) (ER-resident protein ERdj5) (ERdj5) (Macrothioredoxin) (MTHr) DNAJC10 ERDJ5 UNQ495/PRO1012 Homo sapiens (Human) intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of ATP-dependent activity [GO:0032781]; protein folding in endoplasmic reticulum [GO:0034975]; response to endoplasmic reticulum stress [GO:0034976]; ubiquitin-dependent ERAD pathway [GO:0030433] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; membrane [GO:0016020] "ATPase activator activity [GO:0001671]; ATPase binding [GO:0051117]; disulfide oxidoreductase activity [GO:0015036]; Hsp70 protein binding [GO:0030544]; misfolded protein binding [GO:0051787]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein-disulfide reductase activity [GO:0015035]; protein-folding chaperone binding [GO:0051087]" 0.95821 -1.6828 DDYIRDLK 0 0 0 0 0 0 9.14954 0 0 0 10.1642 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IXF0 NPAS3_HUMAN Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Basic-helix-loop-helix-PAS protein MOP6) (Class E basic helix-loop-helix protein 12) (bHLHe12) (Member of PAS protein 6) (PAS domain-containing protein 6) NPAS3 BHLHE12 MOP6 PASD6 Homo sapiens (Human) positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleoplasm [GO:0005654] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.9414 -1.3147 VTGTLAATSTAAQR 0 0 0 0 0 0 9.87853 0 0 0 0 9.22321 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IXH8 CAD26_HUMAN Cadherin-like protein 26 (Cadherin-like protein VR20) CDH26 Homo sapiens (Human) "adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; CD4-positive, alpha-beta T cell activation [GO:0035710]; cell morphogenesis [GO:0000902]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]" adherens junction [GO:0005912]; catenin complex [GO:0016342]; microtubule cytoskeleton [GO:0015630]; plasma membrane [GO:0005886] alpha-catenin binding [GO:0045294]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; delta-catenin binding [GO:0070097]; integrin binding [GO:0005178] 0.96907 -3.9765 DSPFTSAWRAK 8.88222 0 0 0 0 0 0 0 0 0 0 9.18666 0 0 0 9.87158 0 0 9.39294 0 0 0 0 0 0 0 0 Q8IXJ9 ASXL1_HUMAN Polycomb group protein ASXL1 (Additional sex combs-like protein 1) ASXL1 KIAA0978 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; bone marrow development [GO:0048539]; cell morphogenesis [GO:0000902]; chromatin organization [GO:0006325]; heart morphogenesis [GO:0003007]; hemopoiesis [GO:0030097]; homeostasis of number of cells [GO:0048872]; lung saccule development [GO:0060430]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035359]; podocyte development [GO:0072015]; positive regulation of retinoic acid receptor signaling pathway [GO:0048386]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of kidney size [GO:0035564]; response to retinoic acid [GO:0032526]; thymus development [GO:0048538] nucleoplasm [GO:0005654]; PR-DUB complex [GO:0035517] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; nuclear retinoic acid receptor binding [GO:0042974]; peroxisome proliferator activated receptor binding [GO:0042975]; transcription coactivator activity [GO:0003713] 0.91762 -0.86688 ALGDQSNVTGQGKK 16.3275 15.9554 16.3186 9.59872 11.4794 9.96177 15.7163 16.1525 16.1361 10.9388 10.8274 0 0 9.26782 12.5524 0 0 0 9.1518 0 0 0 0 0 0 0 10.3159 Q8IXK0 PHC2_HUMAN Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2) PHC2 EDR2 PH2 Homo sapiens (Human) spermatogenesis [GO:0007283] heterochromatin [GO:0000792]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PcG protein complex [GO:0031519]; PRC1 complex [GO:0035102] DNA binding [GO:0003677]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270] 0.95366 -1.514 VDFAYKFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.02048 0 0 0 0 0 Q8IXK2 GLT12_HUMAN Polypeptide N-acetylgalactosaminyltransferase 12 (EC 2.4.1.41) (Polypeptide GalNAc transferase 12) (GalNAc-T12) (pp-GaNTase 12) (Protein-UDP acetylgalactosaminyltransferase 12) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 12) GALNT12 Homo sapiens (Human) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139] carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; polypeptide N-acetylgalactosaminyltransferase activity [GO:0004653] 0.95887 -1.7779 ELYYHRNPRAR 0 0 0 0 0 0 0 0 0 0 0 0 0 8.29733 0 0 0 0 0 0 0 0 0 0 0 0 9.11379 Q8IXL6 FA20C_HUMAN Extracellular serine/threonine protein kinase FAM20C (EC 2.7.11.1) (Dentin matrix protein 4) (DMP-4) (Golgi casein kinase) (Golgi-enriched fraction casein kinase) (GEF-CK) FAM20C DMP4 Homo sapiens (Human) biomineral tissue development [GO:0031214]; dentinogenesis [GO:0097187]; enamel mineralization [GO:0070166]; odontoblast differentiation [GO:0071895]; osteoclast maturation [GO:0036179]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; post-translational protein modification [GO:0043687]; protein autophosphorylation [GO:0046777]; protein metabolic process [GO:0019538]; protein phosphorylation [GO:0006468]; regulation of fibroblast growth factor receptor signaling pathway [GO:0040036]; regulation of phosphorus metabolic process [GO:0051174] endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654] ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; manganese ion binding [GO:0030145]; protease binding [GO:0002020]; protein kinase activity [GO:0004672]; protein self-association [GO:0043621]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.94118 -1.3148 KTWRNPWR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9375 0 0 0 0 0 0 Q8IXL7 MSRB3_HUMAN Methionine-R-sulfoxide reductase B3 (MsrB3) (EC 1.8.4.12) (EC 1.8.4.14) MSRB3 UNQ1965/PRO4487 Homo sapiens (Human) protein repair [GO:0030091]; response to oxidative stress [GO:0006979] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739] L-methionine-(R)-S-oxide reductase activity [GO:0033745]; peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; zinc ion binding [GO:0008270] 0.96281 -2.6629 KNCKVVFSQQELR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5823 0 10.9347 0 0 0 0 0 Q8IXM3 RM41_HUMAN "Large ribosomal subunit protein mL41 (39S ribosomal protein L41, mitochondrial) (L41mt) (MRP-L41) (Bcl-2-interacting mitochondrial ribosomal protein L41) (Cell proliferation-inducing gene 3 protein) (MRP-L27 homolog)" MRPL41 BMRP MRPL27 RPML27 PIG3 Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; mitochondrial translation [GO:0032543]; translation [GO:0006412] mitochondrial inner membrane [GO:0005743]; mitochondrial large ribosomal subunit [GO:0005762]; mitochondrion [GO:0005739]; ribonucleoprotein complex [GO:1990904] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.93025 -1.2479 CLVRGADRMSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5783 0 0 0 Q8IXM7 OD3L1_HUMAN Outer dense fiber protein 3-like protein 1 ODF3L1 Homo sapiens (Human) cytoskeleton [GO:0005856] 0.76529 0.2827 APQYTFGYR 0 0 0 0 0 0 0 0 0 11.9526 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IXQ4 GPAM1_HUMAN GPALPP motifs-containing protein 1 (Lipopolysaccharide-specific response protein 7) GPALPP1 KIAA1704 LSR7 AD029 Homo sapiens (Human) 0.93272 -1.2765 DEEHILSGR 0 0 0 0 0 0 0 0 0 0 0 8.95513 0 0 0 0 0 0 0 0 0 10.0523 0 0 0 0 0 Q8IXQ6 PARP9_HUMAN Protein mono-ADP-ribosyltransferase PARP9 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 9) (ARTD9) (B aggressive lymphoma protein) (Poly [ADP-ribose] polymerase 9) (PARP-9) PARP9 BAL BAL1 Homo sapiens (Human) cell migration [GO:0016477]; defense response to virus [GO:0051607]; DNA damage checkpoint signaling [GO:0000077]; double-strand break repair [GO:0006302]; innate immune response [GO:0045087]; NAD biosynthesis via nicotinamide riboside salvage pathway [GO:0034356]; negative regulation of catalytic activity [GO:0043086]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of chromatin binding [GO:0035563]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of response to type II interferon [GO:0060330]; viral protein processing [GO:0019082] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; site of DNA damage [GO:0090734] ADP-D-ribose binding [GO:0072570]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; histone binding [GO:0042393]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+-protein-C-terminal glycine ADP-ribosyltransferase activity [GO:0140802]; nucleotidyltransferase activity [GO:0016779]; STAT family protein binding [GO:0097677]; transcription corepressor activity [GO:0003714]; ubiquitin-like protein ligase binding [GO:0044389] 0.41453 0.68651 GNTEECLPYK 10.487 0 0 0 0 8.40403 12.029 12.1548 0 0 0 0 0 0 0 0 0 9.71988 10.9554 0 11.0865 0 10.2868 0 0 0 0 Q8IXQ9 ETKMT_HUMAN Electron transfer flavoprotein beta subunit lysine methyltransferase (EC 2.1.1.-) (ETFB lysine methyltransferase) (ETFB-KMT) (Protein N-lysine methyltransferase METTL20) ETFBKMT C12orf72 METTL20 Homo sapiens (Human) negative regulation of electron transfer activity [GO:1904733]; negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:1904736]; peptidyl-lysine methylation [GO:0018022]; peptidyl-lysine trimethylation [GO:0018023]; protein methylation [GO:0006479] cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; protein-containing complex [GO:0032991] heat shock protein binding [GO:0031072]; protein-lysine N-methyltransferase activity [GO:0016279] 0.87169 0.036776 YLLDNPDVVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.5237 0 0 0 0 0 0 0 0 Q8IXS2 DRC2_HUMAN Dynein regulatory complex subunit 2 (Coiled-coil domain-containing protein 65) (Testis development protein NYD-SP28) CCDC65 DRC2 Homo sapiens (Human) axonemal dynein complex assembly [GO:0070286]; cilium assembly [GO:0060271]; cilium-dependent cell motility [GO:0060285]; regulation of cilium movement [GO:0003352] axonemal dynein complex [GO:0005858]; axoneme [GO:0005930]; ciliary basal body [GO:0036064]; motile cilium [GO:0031514] 0.8846 -0.20851 EIEVQMKK 12.9407 14.755 12.8678 12.765 13.0389 13.0842 14.3091 14.6436 12.7531 14.0144 14.5214 12.3357 13.5103 13.6795 13.7078 14.2544 13.864 0 0 0 0 0 0 0 0 0 0 Q8IXS6 PALM2_HUMAN Paralemmin-2 PALM2 Homo sapiens (Human) regulation of cell shape [GO:0008360] plasma membrane [GO:0005886] 0.88376 -0.29726 GVKVYDDGTK 0 0 0 0 0 0 0 0 0 0 0 0 9.93771 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IXS8 HYCC2_HUMAN Hyccin 2 HYCC2 FAM126B Homo sapiens (Human) phosphatidylinositol phosphate biosynthetic process [GO:0046854]; protein localization to plasma membrane [GO:0072659] cytosol [GO:0005829]; plasma membrane [GO:0005886] 0.96932 -3.1427 ETASAIK 0 0 0 0 0 0 11.1694 16.3787 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7.94603 0 Q8IXT1 DDIAS_HUMAN DNA damage-induced apoptosis suppressor protein (Nitric oxide-inducible gene protein) DDIAS C11orf82 NOXIN Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; regulation of cell cycle [GO:0051726]; regulation of DNA stability [GO:0097752] cytoplasm [GO:0005737]; nucleus [GO:0005634] 0.62126 0.4157 DDFLFNCKGNLSPSVEK 9.76275 9.95587 9.88583 8.9689 0 0 0 0 0 0 0 0 0 0 0 0 9.64935 0 0 0 0 9.58156 0 0 0 0 10.8372 Q8IXT2 DMRTD_HUMAN Doublesex- and mab-3-related transcription factor C2 DMRTC2 Homo sapiens (Human) heterochromatin organization [GO:0070828]; male meiosis I [GO:0007141]; sex differentiation [GO:0007548]; spermatid nucleus elongation [GO:0007290] chromatin [GO:0000785]; nucleus [GO:0005634]; XY body [GO:0001741] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.7228 0.35976 HLMRRGEASPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1529 0 0 0 0 0 0 0 0 0 0 Q8IXT5 RB12B_HUMAN RNA-binding protein 12B (RNA-binding motif protein 12B) RBM12B Homo sapiens (Human) regulation of RNA splicing [GO:0043484] nucleoplasm [GO:0005654]; ribonucleoprotein complex [GO:1990904] RNA binding [GO:0003723] 0.96776 -3.814 DFRQPDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.68975 0 9.56786 0 0 0 0 0 0 0 0 Q8IXW0 LMTD2_HUMAN Lamin tail domain-containing protein 2 LMNTD2 C11orf35 Homo sapiens (Human) lamin filament [GO:0005638] structural constituent of chromatin [GO:0030527] 0.88532 -0.33569 AQWEKEHLEER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1123 Q8IXW5 RPAP2_HUMAN Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 (EC 3.1.3.16) (RNA polymerase II-associated protein 2) RPAP2 C1orf82 Homo sapiens (Human) snRNA transcription [GO:0009301] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription preinitiation complex [GO:0097550] metal ion binding [GO:0046872]; myosin phosphatase activity [GO:0017018]; RNA polymerase core enzyme binding [GO:0043175]; RNA polymerase II CTD heptapeptide repeat phosphatase activity [GO:0008420] 0.92412 -1.028 ANSKHKDK 0 9.98797 0 0 0 0 0 0 0 0 0 10.218 0 0 11.7446 0 0 0 0 0 0 0 0 0 0 0 0 Q8IXX5 T183A_HUMAN Transmembrane protein 183A TMEM183A C1orf37 Homo sapiens (Human) regulation of protein stability [GO:0031647] membrane [GO:0016020]; SCF ubiquitin ligase complex [GO:0019005] 0.78668 0.24965 AVANAVQQEVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.97427 0 0 0 0 0 0 Q8IXZ2 ZC3H3_HUMAN Zinc finger CCCH domain-containing protein 3 (Smad-interacting CPSF-like factor) ZC3H3 KIAA0150 SMICL ZC3HDC3 Homo sapiens (Human) mRNA 3'-end processing [GO:0031124]; mRNA transport [GO:0051028]; positive regulation of activin receptor signaling pathway [GO:0032927]; regulation of mRNA polyadenylation [GO:1900363] mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872]; R-SMAD binding [GO:0070412] 0.96896 -4.4569 EYCMYYNRFGR 0 0 0 0 8.5108 8.82085 0 0 0 10.2192 0 0 0 0 0 0 0 0 0 10.7474 0 0 0 0 0 0 0 Q8IY17 PLPL6_HUMAN Patatin-like phospholipase domain-containing protein 6 (EC 3.1.1.5) (Neuropathy target esterase) PNPLA6 NTE Homo sapiens (Human) glycerophospholipid catabolic process [GO:0046475]; phosphatidylcholine metabolic process [GO:0046470] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] lysophospholipase activity [GO:0004622]; phosphatidyl phospholipase B activity [GO:0102545] 0.95952 -1.8513 LFPSPGLPTRTSPVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5384 0 8.42895 0 0 0 10.1107 9.6271 9.22608 Q8IY18 SMC5_HUMAN Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5) (hSMC5) SMC5 KIAA0594 SMC5L1 Homo sapiens (Human) "cell division [GO:0051301]; cellular senescence [GO:0090398]; chromosome condensation [GO:0030261]; chromosome segregation [GO:0007059]; DNA damage response [GO:0006974]; double-strand break repair via homologous recombination [GO:0000724]; internal peptidyl-lysine acetylation [GO:0018393]; mitotic cell cycle phase transition [GO:0044772]; negative regulation by host of viral genome replication [GO:0044828]; positive regulation of chromosome segregation [GO:0051984]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; protein localization to chromosome, centromeric region [GO:0071459]; protein sumoylation [GO:0016925]; regulation of telomere maintenance [GO:0032204]; stem cell population maintenance [GO:0019827]; telomere maintenance via recombination [GO:0000722]" "cell junction [GO:0030054]; chromosome, centromeric region [GO:0000775]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; interchromatin granule [GO:0035061]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; sex chromosome [GO:0000803]; site of double-strand break [GO:0035861]; Smc5-Smc6 complex [GO:0030915]" ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA secondary structure binding [GO:0000217]; single-stranded DNA binding [GO:0003697] 0.96862 -8.6177 APSRSLNELK 9.6691 0 12.2723 0 0 0 11.0967 10.2378 0 10.6628 0 10.8297 0 0 10.6589 0 8.99955 0 0 10.0701 0 0 0 7.75449 0 0 0 Q8IY21 DDX60_HUMAN Probable ATP-dependent RNA helicase DDX60 (EC 3.6.4.13) (DEAD box protein 60) DDX60 Homo sapiens (Human) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; response to virus [GO:0009615] cytoplasm [GO:0005737]; cytosol [GO:0005829]; intermediate filament cytoskeleton [GO:0045111] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; double-stranded DNA binding [GO:0003690]; double-stranded RNA binding [GO:0003725]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727] 0.1645 0.97832 AEIIARENKK 9.58227 9.30599 0 0 0 0 0 0 0 8.58692 0 0 0 0 0 0 9.39333 0 0 0 0 0 0 0 0 0 0 Q8IY22 CMIP_HUMAN C-Maf-inducing protein (c-Mip) (Truncated c-Maf-inducing protein) (Tc-Mip) CMIP KIAA1694 TCMIP Homo sapiens (Human) in utero embryonic development [GO:0001701] cytosol [GO:0005829]; nucleoplasm [GO:0005654] 0.95103 -1.421 FAEDPRQEVHSCLLSVRAGK 0 0 0 0 0 0 0 12.3183 0 0 0 0 0 0 13.2445 0 0 0 0 0 0 0 0 0 0 0 0 Q8IY37 DHX37_HUMAN Probable ATP-dependent RNA helicase DHX37 (EC 3.6.4.13) (DEAH box protein 37) DHX37 DDX37 KIAA1517 Homo sapiens (Human) "brain development [GO:0007420]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; positive regulation of male gonad development [GO:2000020]; ribosomal small subunit biogenesis [GO:0042274]; ribosome assembly [GO:0042255]; ribosome biogenesis [GO:0042254]" cytoplasm [GO:0005737]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; helicase activity [GO:0004386]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; U3 snoRNA binding [GO:0034511] 0.73012 0.33409 AERVKQLQENR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.577 10.4797 Q8IY42 CD019_HUMAN Uncharacterized protein C4orf19 C4orf19 Homo sapiens (Human) 0.94999 -1.3813 WSSEVLVQKNDPQRQGSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.90002 0 0 Q8IY47 KBTB2_HUMAN Kelch repeat and BTB domain-containing protein 2 (BTB and kelch domain-containing protein 1) KBTBD2 BKLHD1 KIAA1489 CGI-73 Homo sapiens (Human) gene expression [GO:0010467]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; phosphatidylinositol 3-kinase signaling [GO:0014065]; protein ubiquitination [GO:0016567]; response to insulin [GO:0032868] 0.62396 0.41412 TVERYDTEK 0 0 0 0 0 0 0 0 0 0 0 9.48798 0 10.4209 0 0 0 0 0 0 0 0 8.60203 0 0 0 0 Q8IY63 AMOL1_HUMAN Angiomotin-like protein 1 AMOTL1 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; angiogenesis [GO:0001525]; establishment of cell polarity involved in ameboidal cell migration [GO:0003365]; hippo signaling [GO:0035329]; regulation of cell migration [GO:0030334]; Wnt signaling pathway [GO:0016055] bicellular tight junction [GO:0005923]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; plasma membrane [GO:0005886] identical protein binding [GO:0042802] 0.059305 1.3622 ESLDKAMRNK 11.681 0 0 0 10.4449 10.4561 0 0 11.3399 10.7648 11.307 10.9546 10.0939 0 9.95485 0 0 11.5212 0 0 0 0 0 0 0 9.48444 0 Q8IY81 SPB1_HUMAN pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 (EC 2.1.1.-) (Protein ftsJ homolog 3) (Putative rRNA methyltransferase 3) FTSJ3 SB92 Homo sapiens (Human) "maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; RNA methylation [GO:0001510]; rRNA methylation [GO:0031167]" "chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; preribosome, large subunit precursor [GO:0030687]; preribosome, small subunit precursor [GO:0030688]" RNA 2'-O-methyltransferase activity [GO:0062105]; RNA binding [GO:0003723]; rRNA (guanine) methyltransferase activity [GO:0016435]; rRNA (uridine-2'-O-)-methyltransferase activity [GO:0008650] 0.96952 -3.1647 AANPVDFLSK 0 0 11.3984 0 0 0 0 0 9.91358 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.98445 0 0 11.4689 Q8IY82 DRC7_HUMAN Dynein regulatory complex subunit 7 (Coiled-coil domain-containing protein 135) (Coiled-coil domain-containing protein lobo homolog) DRC7 C16orf50 CCDC135 Homo sapiens (Human) flagellated sperm motility [GO:0030317]; sperm axoneme assembly [GO:0007288]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; motile cilium [GO:0031514] 0.95962 -1.9091 DECLSDFK 0 14.2111 14.1948 11.6644 0 11.8569 0 0 13.5095 13.5855 0 13.7836 0 13.039 0 0 13.8455 0 10.5641 0 0 10.4223 9.85806 0 0 0 0 Q8IY85 EFC13_HUMAN EF-hand calcium-binding domain-containing protein 13 EFCAB13 C17orf57 Homo sapiens (Human) 0.92279 -1.1485 EISPEIRSLSPEYK 0 0 0 0 0 0 0 11.3287 0 0 0 0 0 9.95324 0 0 0 0 0 9.79894 0 9.67248 0 0 0 10.8339 11.6954 Q8IY92 SLX4_HUMAN Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12) SLX4 BTBD12 KIAA1784 KIAA1987 Homo sapiens (Human) DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; nucleotide-excision repair [GO:0006289]; positive regulation of t-circle formation [GO:1904431]; positive regulation of telomere maintenance [GO:0032206]; resolution of meiotic recombination intermediates [GO:0000712]; response to intra-S DNA damage checkpoint signaling [GO:0072429]; t-circle formation [GO:0090656]; telomeric D-loop disassembly [GO:0061820] "cell junction [GO:0030054]; chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; Slx1-Slx4 complex [GO:0033557]" DNA binding [GO:0003677]; enzyme activator activity [GO:0008047]; metal ion binding [GO:0046872] 0.88524 -0.24179 FGVRPLPKR 0 0 0 0 0 0 0 0 0 11.3613 0 0 0 0 0 0 10.1933 0 9.9737 10.4005 0 0 0 0 0 10.0396 0 Q8IYA6 CKP2L_HUMAN Cytoskeleton-associated protein 2-like (Radial fiber and mitotic spindle protein) (Radmis) CKAP2L Homo sapiens (Human) centrosome [GO:0005813]; cytosol [GO:0005829]; microtubule cytoskeleton [GO:0015630]; mitotic spindle [GO:0072686]; spindle pole [GO:0000922] 0.89967 -0.61159 FAKFWICKAK 0 0 0 11.129 11.4646 0 12.7918 8.75822 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IYA7 MKX_HUMAN Homeobox protein Mohawk MKX C10orf48 IRXL1 Homo sapiens (Human) cell development [GO:0048468]; muscle organ development [GO:0007517]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96499 -2.3785 ASEDYVAPPK 0 0 0 0 0 0 0 0 0 0 10.5289 0 0 9.97111 0 0 0 0 0 0 8.78754 0 10.09 0 0 0 0 Q8IYB0 YK038_HUMAN Putative uncharacterized protein MGC39545 Homo sapiens (Human) 0.2688 0.84413 PSGEERR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.80821 0 Q8IYB1 M21D2_HUMAN Nucleotidyltransferase MB21D2 (EC 2.7.7.-) (Mab-21 domain-containing protein 2) (hMB21D2) MB21D2 C3orf59 Homo sapiens (Human) cadherin binding [GO:0045296]; nucleotidyltransferase activity [GO:0016779]; protein-containing complex binding [GO:0044877] 0.35635 0.75521 LFDEGTISK 0 0 0 0 0 0 0 0 0 0 9.18864 8.61456 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IYB3 SRRM1_HUMAN Serine/arginine repetitive matrix protein 1 (SR-related nuclear matrix protein of 160 kDa) (SRm160) (Ser/Arg-related nuclear matrix protein) SRRM1 SRM160 Homo sapiens (Human) "localization [GO:0051179]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA splicing, via spliceosome [GO:0048024]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]" catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681] DNA binding [GO:0003677]; RNA binding [GO:0003723] 0.96929 -4.4756 EKALRSMR 0 12.0092 12.0591 0 0 0 9.6743 0 0 0 11.6706 10.5991 0 0 0 0 0 0 0 9.2078 8.89875 0 0 0 0 0 0 Q8IYB4 PEX5R_HUMAN PEX5-related protein (PEX2-related protein) (PEX5-like protein) (Peroxin-5-related protein) (Peroxisome biogenesis factor 5-like) (Tetratricopeptide repeat-containing Rab8b-interacting protein) (Pex5Rp) (TRIP8b) PEX5L PEX5R PXR2 Homo sapiens (Human) "protein import into peroxisome matrix, docking [GO:0016560]; regulation of cAMP-mediated signaling [GO:0043949]" cytosol [GO:0005829]; peroxisomal membrane [GO:0005778]; receptor complex [GO:0043235] peroxisome matrix targeting signal-1 binding [GO:0005052]; peroxisome targeting sequence binding [GO:0000268]; small GTPase binding [GO:0031267] 0.9319 -1.2568 AVAMVMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.66612 0 0 Q8IYB5 SMAP1_HUMAN Stromal membrane-associated protein 1 SMAP1 Homo sapiens (Human) positive regulation of erythrocyte differentiation [GO:0045648]; regulation of clathrin-dependent endocytosis [GO:2000369] cytoplasm [GO:0005737]; plasma membrane [GO:0005886] clathrin binding [GO:0030276]; GTPase activator activity [GO:0005096]; metal ion binding [GO:0046872] 0.96786 -2.8707 LEKEKEK 9.8069 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IYB7 DI3L2_HUMAN DIS3-like exonuclease 2 (hDIS3L2) (EC 3.1.13.-) DIS3L2 FAM6A Homo sapiens (Human) "cell division [GO:0051301]; miRNA catabolic process [GO:0010587]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid separation [GO:0051306]; mRNA catabolic process [GO:0006402]; negative regulation of cell population proliferation [GO:0008285]; nuclear-transcribed mRNA catabolic process, exonucleolytic [GO:0000291]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyuridylation-dependent mRNA catabolic process [GO:1990074]; stem cell population maintenance [GO:0019827]" cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; P-body [GO:0000932]; polysome [GO:0005844] 3'-5'-RNA exonuclease activity [GO:0000175]; magnesium ion binding [GO:0000287]; poly(U) RNA binding [GO:0008266]; RNA nuclease activity [GO:0004540] 0.96965 -3.5089 FVDGALRLDQLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.92038 0 10.0821 0 0 0 10.8467 0 12.2013 0 0 0 Q8IYB8 SUV3_HUMAN "ATP-dependent RNA helicase SUPV3L1, mitochondrial (EC 3.6.4.13) (Suppressor of var1 3-like protein 1) (SUV3-like protein 1)" SUPV3L1 SUV3 Homo sapiens (Human) DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; mitochondrial mRNA catabolic process [GO:0000958]; mitochondrial mRNA surveillance [GO:0035946]; mitochondrial ncRNA surveillance [GO:0035945]; mitochondrial RNA 3'-end processing [GO:0000965]; mitochondrial RNA surveillance [GO:2000827]; mitochondrion morphogenesis [GO:0070584]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell growth [GO:0030307]; positive regulation of mitochondrial RNA catabolic process [GO:0000962]; RNA catabolic process [GO:0006401] mitochondrial degradosome [GO:0045025]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; nucleus [GO:0005634] 3'-5' RNA helicase activity [GO:0034458]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.92506 -0.97349 EKTESGTHPK 0 0 0 0 0 0 9.11119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IYB9 ZN595_HUMAN Zinc finger protein 595 ZNF595 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96241 -2.4852 AFTRSTALNEHK 10.7512 0 0 0 10.4446 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IYD2 KLD8A_HUMAN Kelch domain-containing protein 8A (Substitute for delta-EGFR expression 1) (S-delta-E1) KLHDC8A Homo sapiens (Human) 0.8971 -0.58417 MEVPNVKDFQWK 0 0 0 0 0 0 0 0 0 9.77775 10.8515 9.74185 0 0 0 0 0 0 0 0 0 8.86081 0 0 0 0 0 Q8IYD8 FANCM_HUMAN Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog) FANCM KIAA1596 Homo sapiens (Human) double-strand break repair via synthesis-dependent strand annealing [GO:0045003]; interstrand cross-link repair [GO:0036297]; positive regulation of protein monoubiquitination [GO:1902527]; replication fork processing [GO:0031297]; resolution of meiotic recombination intermediates [GO:0000712] chromatin [GO:0000785]; FANCM-MHF complex [GO:0071821]; Fanconi anaemia nuclear complex [GO:0043240]; nucleoplasm [GO:0005654] 3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; chromatin binding [GO:0003682]; four-way junction DNA binding [GO:0000400]; four-way junction helicase activity [GO:0009378]; nuclease activity [GO:0004518]; RNA helicase activity [GO:0003724] 0.11775 1.1039 ELSLVEQR 0 0 0 0 9.52757 0 0 0 0 0 9.29925 0 0 11.4163 0 0 0 0 0 0 0 0 9.07329 0 0 0 0 Q8IYE0 CC146_HUMAN Coiled-coil domain-containing protein 146 CCDC146 KIAA1505 Homo sapiens (Human) centriole [GO:0005814]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856] 0.90669 -0.71233 GLPLNKEIEKEWLK 0 0 0 0 0 0 0 10.0236 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2737 9.76502 0 Q8IYE1 CCD13_HUMAN Coiled-coil domain-containing protein 13 CCDC13 Homo sapiens (Human) cytoplasmic microtubule organization [GO:0031122]; DNA damage response [GO:0006974]; non-motile cilium assembly [GO:1905515] cell projection [GO:0042995]; centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654] 0.92214 -1.0859 GRAQQILVLQSKVQELEK 0 0 0 0 0 0 10.0614 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.43981 0 0 Q8IYF1 ELOA2_HUMAN Elongin-A2 (EloA2) (RNA polymerase II transcription factor SIII subunit A2) (Transcription elongation factor B polypeptide 3B) ELOA2 TCEB3B TCEB3L Homo sapiens (Human) regulation of DNA-templated transcription elongation [GO:0032784]; transcription by RNA polymerase II [GO:0006366]; transcription elongation by RNA polymerase II [GO:0006368] elongin complex [GO:0070449]; nucleoplasm [GO:0005654] 0.84081 0.14417 LQAAGADSAGPK 0 0 0 0 0 0 0 0 0 0 9.93693 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IYF3 TEX11_HUMAN Testis-expressed protein 11 (Protein ZIP4 homolog) (ZIP4H) TEX11 ZIP4 Homo sapiens (Human) apoptotic process [GO:0006915]; chiasma assembly [GO:0051026]; ectopic germ cell programmed cell death [GO:0035234]; fertilization [GO:0009566]; male gonad development [GO:0008584]; male meiosis chromosome segregation [GO:0007060]; meiotic gene conversion [GO:0006311]; negative regulation of apoptotic process [GO:0043066]; negative regulation of developmental process [GO:0051093]; negative regulation of reproductive process [GO:2000242]; reciprocal meiotic recombination [GO:0007131]; resolution of meiotic recombination intermediates [GO:0000712]; synaptonemal complex assembly [GO:0007130] central element [GO:0000801]; chromosome [GO:0005694] 0.8985 -0.57956 LFSDIANINR 0 0 0 0 0 0 10.7668 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.8867 0 0 10.3497 Q8IYG6 LRC56_HUMAN Leucine-rich repeat-containing protein 56 LRRC56 Homo sapiens (Human) cell projection organization [GO:0030030] cilium [GO:0005929] 0.92237 -1.1202 VPRGYNYRAEVR 17.2836 0 0 15.9495 0 0 0 17.174 0 0 0 0 0 0 0 0 0 0 0 0 0 12.3493 0 0 0 0 0 Q8IYH5 ZZZ3_HUMAN ZZ-type zinc finger-containing protein 3 ZZZ3 Homo sapiens (Human) chromatin organization [GO:0006325]; histone H3-K14 acetylation [GO:0044154]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of DNA-templated transcription [GO:0006355]; regulation of embryonic development [GO:0045995]; regulation of histone deacetylation [GO:0031063]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tubulin deacetylation [GO:0090043] ATAC complex [GO:0140672]; mitotic spindle [GO:0072686]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] DNA binding [GO:0003677]; lysine-acetylated histone binding [GO:0070577]; methylated histone binding [GO:0035064]; zinc ion binding [GO:0008270] 0.96943 -6.286 LTKAGIPVPGR 0 0 8.95803 0 0 8.33307 0 8.49161 0 0 0 11.1016 0 0 0 0 0 0 10.2239 0 0 0 0 0 0 0 0 Q8IYI6 EXOC8_HUMAN Exocyst complex component 8 (Exocyst complex 84 kDa subunit) EXOC8 Homo sapiens (Human) endosome organization [GO:0007032]; exocytosis [GO:0006887]; extracellular matrix disassembly [GO:0022617]; Golgi to plasma membrane transport [GO:0006893]; membrane fission [GO:0090148]; mitotic cytokinesis [GO:0000281]; protein localization [GO:0008104]; protein transport [GO:0015031]; regulation of macroautophagy [GO:0016241]; vesicle docking involved in exocytosis [GO:0006904]; vesicle tethering involved in exocytosis [GO:0090522] cell leading edge [GO:0031252]; cytosol [GO:0005829]; exocyst [GO:0000145]; growth cone [GO:0030426]; late endosome [GO:0005770]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] phosphatidylinositol binding [GO:0035091]; small GTPase binding [GO:0031267] 0.96961 -3.9556 AKVEERVR 0 0 0 8.22139 0 0 0 0 0 0 0 10.5389 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IYI8 ZN440_HUMAN Zinc finger protein 440 ZNF440 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.9327 -1.276 IHTGEKPCECK 11.544 11.4185 0 0 10.2699 10.2648 11.2106 0 11.1634 0 11.47 0 0 0 10.3073 0 0 9.20745 0 0 0 0 0 0 0 0 0 Q8IYJ1 CPNE9_HUMAN Copine-9 (Copine IX) CPNE9 Homo sapiens (Human) cell differentiation [GO:0030154]; cellular response to calcium ion [GO:0071277]; positive regulation of dendrite extension [GO:1903861] extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] calcium-dependent phospholipid binding [GO:0005544]; metal ion binding [GO:0046872] 0.96538 -2.7124 ASQEWREFGR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.40918 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IYJ3 SYTL1_HUMAN Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) SYTL1 SLP1 SB146 Homo sapiens (Human) exocytosis [GO:0006887]; intracellular protein transport [GO:0006886] exocytic vesicle [GO:0070382]; extracellular exosome [GO:0070062]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886] neurexin family protein binding [GO:0042043]; small GTPase binding [GO:0031267] 0.84798 0.17271 LTIDEAPQER 0 0 0 0 0 0 16.2018 0 16.1514 0 0 0 0 0 0 0 0 0 0 0 9.87573 0 0 9.84444 9.58212 0 0 Q8IYK4 GT252_HUMAN Procollagen galactosyltransferase 2 (EC 2.4.1.50) (Collagen beta(1-O)galactosyltransferase 2) (ColGalT 2) (Glycosyltransferase 25 family member 2) (Hydroxylysine galactosyltransferase 2) COLGALT2 C1orf17 GLT25D2 KIAA0584 Homo sapiens (Human) collagen fibril organization [GO:0030199] endoplasmic reticulum lumen [GO:0005788] procollagen galactosyltransferase activity [GO:0050211] 0.57545 0.47723 QAGIQMYLCNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.67034 0 0 0 0 0 0 10.3904 0 0 Q8IYK8 REM2_HUMAN GTP-binding protein REM 2 (Rad and Gem-like GTP-binding protein 2) REM2 Homo sapiens (Human) plasma membrane [GO:0005886] calcium channel regulator activity [GO:0005246]; GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.8353 0.18791 FLANLVPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.9053 0 0 0 9.7837 0 Q8IYL2 TRM44_HUMAN Probable tRNA (uracil-O(2)-)-methyltransferase (EC 2.1.1.211) (Methyltransferase-like protein 19) TRMT44 C4orf23 METTL19 Homo sapiens (Human) tRNA methylation [GO:0030488] cytoplasm [GO:0005737] metal ion binding [GO:0046872]; tRNA (uracil) methyltransferase activity [GO:0016300]; tRNA (uracil-2'-O-)-methyltransferase activity [GO:0052665] 0.95269 -1.4699 GPGTSAGSEQK 0 8.34216 0 0 0 0 0 0 0 0 0 9.44543 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IYL3 CA174_HUMAN UPF0688 protein C1orf174 C1orf174 Homo sapiens (Human) nucleoplasm [GO:0005654] 0.84737 0.13027 LASAQEVAGSTSAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9838 0 Q8IYL9 PSYR_HUMAN Psychosine receptor (G-protein coupled receptor 65) (T-cell death-associated gene 8 protein) GPR65 TDAG8 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; apoptotic process [GO:0006915]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of stress fiber assembly [GO:0051496]; response to acidic pH [GO:0010447] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930] 0.94002 -1.3261 ATENKEK 0 0 0 0 0 0 0 0 0 0 0 0 8.72639 0 0 0 10.8601 0 0 0 0 0 0 0 0 0 0 Q8IYM0 F186B_HUMAN Protein FAM186B FAM186B C12orf25 Homo sapiens (Human) protein-containing complex [GO:0032991] 0.96216 -2.6258 IEAAQLTR 0 0 0 9.71339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.049 0 0 10.0417 0 0 0 0 Q8IYM9 TRI22_HUMAN E3 ubiquitin-protein ligase TRIM22 (EC 2.3.2.27) (50 kDa-stimulated trans-acting factor) (RING finger protein 94) (RING-type E3 ubiquitin transferase TRIM22) (Staf-50) (Tripartite motif-containing protein 22) TRIM22 RNF94 STAF50 Homo sapiens (Human) defense response to virus [GO:0051607]; immune response [GO:0006955]; innate immune response [GO:0045087]; positive regulation of autophagy [GO:0010508]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; regulation of viral entry into host cell [GO:0046596]; response to virus [GO:0009615] Cajal body [GO:0015030]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nuclear body [GO:0016604]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein-macromolecule adaptor activity [GO:0030674]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.88576 -0.33235 LEDDIRQER 0 0 0 0 0 0 0 0 0 0 0 8.57539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IYN0 ZN100_HUMAN Zinc finger protein 100 ZNF100 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.92012 -0.91268 VFHTFSNSNRHK 10.7204 0 0 0 0 0 10.719 10.8436 0 11.0851 11.0882 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IYN2 TCAL8_HUMAN Transcription elongation factor A protein-like 8 (TCEA-like protein 8) (Transcription elongation factor S-II protein-like 8) TCEAL8 Homo sapiens (Human) nucleus [GO:0005634] 0.92449 -1.0682 HSRSRPYPVCFRP 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.66162 0 0 0 0 0 0 0 0 0 0 0 Q8IYQ7 THNS1_HUMAN Threonine synthase-like 1 (TSH1) THNSL1 Homo sapiens (Human) cytoplasm [GO:0005737] 0.87217 0.029 IVGQNSGTSMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.75191 0 0 0 0 Q8IYR2 SMYD4_HUMAN SET and MYND domain-containing protein 4 (EC 2.1.1.-) SMYD4 KIAA1936 Homo sapiens (Human) heart development [GO:0007507]; methylation [GO:0032259] cytoplasm [GO:0005737]; nucleus [GO:0005634] histone deacetylase binding [GO:0042826]; metal ion binding [GO:0046872]; methyltransferase activity [GO:0008168] 0.9227 -1.0592 DLPVDEWK 0 0 9.06738 0 0 0 0 8.85343 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IYS4 DAAF8_HUMAN Dynein axonemal assembly factor 8 (Dynein axonemal-associated protein 1) DNAAF8 C16orf71 DAAP1 Homo sapiens (Human) outer dynein arm assembly [GO:0036158] dynein axonemal particle [GO:0120293] dynein complex binding [GO:0070840] 0.84323 0.15187 GQSAQAR 0 0 0 0 0 0 0 0 0 0 11.7137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IYT1 GAR4_HUMAN Golgi-associated RAB2 interactor protein 4 (Golgi-associated Rab2B interactor-like 4) (GARI-L4) (GARI-like 4) GARIN4 FAM71A Homo sapiens (Human) Golgi organization [GO:0007030] Golgi apparatus [GO:0005794]; nucleus [GO:0005634] 0.9231 -1.0797 SSFSHRANR 0 0 0 0 8.49753 0 0 0 0 0 0 0 0 9.86641 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IYT3 CC170_HUMAN Coiled-coil domain-containing protein 170 CCDC170 C6orf97 Homo sapiens (Human) microtubule cytoskeleton organization [GO:0000226] ciliary basal body [GO:0036064]; Golgi apparatus [GO:0005794] microtubule binding [GO:0008017] 0.93229 -1.2598 DLRKENEFVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9581 Q8IYT4 KATL2_HUMAN Katanin p60 ATPase-containing subunit A-like 2 (Katanin p60 subunit A-like 2) (EC 5.6.1.1) (p60 katanin-like 2) KATNAL2 Homo sapiens (Human) cytoplasmic microtubule organization [GO:0031122]; microtubule severing [GO:0051013] cytoplasm [GO:0005737]; katanin complex [GO:0008352]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; spindle [GO:0005819]; spindle pole [GO:0000922] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; isomerase activity [GO:0016853]; microtubule binding [GO:0008017]; microtubule severing ATPase activity [GO:0008568] 0.041394 1.5035 EAAMRPVR 9.39069 9.36859 9.24743 0 0 0 9.42668 9.61921 0 9.69441 9.73924 10.3077 9.99901 0 10.3272 0 10.4548 10.4903 0 0 0 0 9.54187 0 0 10.655 0 Q8IYT8 ULK2_HUMAN Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2) ULK2 KIAA0623 Homo sapiens (Human) autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; axon extension [GO:0048675]; collateral sprouting [GO:0048668]; late nucleophagy [GO:0044805]; negative regulation of collateral sprouting [GO:0048671]; peptidyl-serine phosphorylation [GO:0018105]; piecemeal microautophagy of the nucleus [GO:0034727]; positive regulation of autophagy [GO:0010508]; protein autophosphorylation [GO:0046777]; response to starvation [GO:0042594]; reticulophagy [GO:0061709]; signal transduction [GO:0007165] autophagosome [GO:0005776]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; membrane [GO:0016020]; phagophore assembly site [GO:0000407]; phagophore assembly site membrane [GO:0034045] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96943 -4.065 FCITMCKKLTEK 0 9.46404 0 0 0 0 9.11119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IYU2 HACE1_HUMAN E3 ubiquitin-protein ligase HACE1 (EC 2.3.2.26) (HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1) (HECT-type E3 ubiquitin transferase HACE1) HACE1 KIAA1320 Homo sapiens (Human) cell cycle [GO:0007049]; Golgi organization [GO:0007030]; membrane fusion [GO:0061025]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; Rac protein signal transduction [GO:0016601]; regulation of cell migration [GO:0030334]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; nuclear body [GO:0016604]; nucleus [GO:0005634] small GTPase binding [GO:0031267]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.9316 -1.2516 LPEYPSKEILK 0 9.8691 0 9.46864 0 0 0 0 0 10.5012 8.61055 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IYU8 MICU2_HUMAN "Calcium uptake protein 2, mitochondrial (EF-hand domain-containing family member A1)" MICU2 EFHA1 Homo sapiens (Human) calcium import into the mitochondrion [GO:0036444]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transmembrane transport [GO:0006851]; negative regulation of mitochondrial calcium ion concentration [GO:0051562]; positive regulation of mitochondrial calcium ion concentration [GO:0051561] calcium channel complex [GO:0034704]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; uniplex complex [GO:1990246] calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982] 0.92435 -0.98622 DGSFTVSAQK 0 9.42828 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IYW2 CFA46_HUMAN Cilia- and flagella-associated protein 46 (Tetratricopeptide repeat protein 40) CFAP46 C10orf123 C10orf124 C10orf92 C10orf93 TTC40 Homo sapiens (Human) axoneme assembly [GO:0035082]; cilium movement involved in cell motility [GO:0060294] axoneme [GO:0005930] 0.96615 -2.7287 AIMAVEQAK 0 0 0 12.3686 0 0 0 9.90956 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.07692 9.3282 0 0 Q8IYW5 RN168_HUMAN E3 ubiquitin-protein ligase RNF168 (hRNF168) (EC 2.3.2.27) (RING finger protein 168) (RING-type E3 ubiquitin transferase RNF168) RNF168 Homo sapiens (Human) DNA damage response [GO:0006974]; DNA repair-dependent chromatin remodeling [GO:0140861]; double-strand break repair [GO:0006302]; double-strand break repair via nonhomologous end joining [GO:0006303]; epigenetic regulation of gene expression [GO:0040029]; histone H2A-K15 ubiquitination [GO:0036352]; interstrand cross-link repair [GO:0036297]; isotype switching [GO:0045190]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; positive regulation of DNA repair [GO:0045739]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; response to ionizing radiation [GO:0010212]; ubiquitin-dependent protein catabolic process [GO:0006511] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; ubiquitin ligase complex [GO:0000151] chromatin binding [GO:0003682]; histone binding [GO:0042393]; histone H2AK15 ubiquitin ligase activity [GO:0140858]; histone ubiquitin ligase activity [GO:0140852]; K63-linked polyubiquitin modification-dependent protein binding [GO:0070530]; metal ion binding [GO:0046872]; nucleosome binding [GO:0031491]; ubiquitin binding [GO:0043130]; ubiquitin-protein transferase activity [GO:0004842] 0.9696 -3.22 DIDSSDR 0 0 0 0 0 0 0 0 0 0 0 0 8.78914 0 0 0 0 8.63575 0 0 0 0 0 0 0 0 0 Q8IYX3 CC116_HUMAN Coiled-coil domain-containing protein 116 CCDC116 Homo sapiens (Human) centrosome [GO:0005813]; cytoplasm [GO:0005737] 0.88372 -0.25925 DEDQDEDKDEDGV 12.0298 12.0905 11.8053 8.92573 8.9587 8.88579 12.2108 12.4065 12.289 11.094 11.0703 13.0224 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IYX7 SAXO1_HUMAN Stabilizer of axonemal microtubules 1 SAXO1 C9orf138 FAM154A Homo sapiens (Human) cell projection organization [GO:0030030]; cellular response to cold [GO:0070417]; cold acclimation [GO:0009631]; positive regulation of cilium assembly [GO:0045724]; protein stabilization [GO:0050821] axonemal microtubule [GO:0005879]; centriole [GO:0005814]; ciliary basal body [GO:0036064]; cytoskeleton [GO:0005856]; motile cilium [GO:0031514]; sperm flagellum [GO:0036126] microtubule binding [GO:0008017] 0.73826 0.32508 VDPIKPR 14.887 15.0377 14.8156 12.4017 11.7425 11.8207 14.8656 14.7762 14.749 15.4002 15.3902 15.0887 12.8021 12.7409 12.8713 12.8751 12.8605 12.6853 12.1494 11.9583 12.2785 11.514 11.5481 11.4152 12.8763 12.7068 12.6152 Q8IYY4 DZI1L_HUMAN Cilium assembly protein DZIP1L (DAZ-interacting zinc finger protein 1-like) DZIP1L Homo sapiens (Human) ciliary transition zone assembly [GO:1905349]; cilium assembly [GO:0060271]; floor plate development [GO:0033504]; neural tube patterning [GO:0021532]; protein localization to cilium [GO:0061512]; regulation of protein localization [GO:0032880]; smoothened signaling pathway [GO:0007224] axoneme [GO:0005930]; centriole [GO:0005814]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737] metal ion binding [GO:0046872] 0.96198 -2.4674 AAAQSQCQISTLR 0 0 11.0759 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2488 0 0 11.6128 0 9.32753 Q8IZ07 AN13A_HUMAN Ankyrin repeat domain-containing protein 13A (Protein KE03) ANKRD13A ANKRD13 Homo sapiens (Human) negative regulation of protein localization to endosome [GO:1905667]; negative regulation of receptor internalization [GO:0002091] cytoplasm [GO:0005737]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] ubiquitin-dependent protein binding [GO:0140036] 0.87947 0.018239 LTLDLMKPK 0 0 0 0 0 0 10.1311 0 0 0 10.3864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IZ13 F200C_HUMAN Protein FAM200C (Protein ZBED8) (Transposon-derived Buster3 transposase-like protein) (Zinc finger BED domain-containing protein 8) FAM200C Buster3 C5orf54 ZBED8 Homo sapiens (Human) nucleoplasm [GO:0005654] 0.8832 -0.087755 HLNELSASMQRTGMNTVSAREK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4839 0 0 0 0 0 0 0 0 0 0 Q8IZ40 RCOR2_HUMAN REST corepressor 2 RCOR2 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; histone deacetylase complex [GO:0000118]; transcription regulator complex [GO:0005667] enzyme binding [GO:0019899]; transcription corepressor activity [GO:0003714] 0.91331 -0.78637 KEVQVSQYR 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3272 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IZ41 RASEF_HUMAN Ras and EF-hand domain-containing protein (Ras-related protein Rab-45) RASEF RAB45 Homo sapiens (Human) vesicle-mediated transport [GO:0016192] cytoplasm [GO:0005737]; cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471] calcium ion binding [GO:0005509]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802] 0.96939 -4.6106 DPNEYDSEVEYKHQRGFQR 11.4997 0 0 0 0 0 9.9499 10.5038 10.6595 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IZ57 NRSN1_HUMAN Neurensin-1 (Neuro-p24) (Vesicular membrane protein of 24 kDa) (Vesicular membrane protein p24) NRSN1 VMP Homo sapiens (Human) nervous system development [GO:0007399] cytoplasmic vesicle [GO:0031410]; growth cone [GO:0030426]; membrane [GO:0016020]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; transport vesicle [GO:0030133] 0.92292 -1.0616 EEKFLQQK 0 0 0 0 0 0 0 0 0 0 9.56565 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IZ63 PRR22_HUMAN Proline-rich protein 22 PRR22 Homo sapiens (Human) 0.75929 0.29266 VLLEDAMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.82903 0 0 0 0 0 0 Q8IZ69 TRM2A_HUMAN tRNA (uracil-5-)-methyltransferase homolog A (EC 2.1.1.35) (mRNA (uracil-5-)-methyltransferase TRMT2A) (EC 2.1.1.-) TRMT2A Homo sapiens (Human) mRNA processing [GO:0006397] cytosol [GO:0005829] C-methyltransferase activity [GO:0008169]; RNA binding [GO:0003723]; S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity [GO:0030697] 0.96182 -2.5603 EIGSTNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.24703 0 Q8IZ81 ELMD2_HUMAN ELMO domain-containing protein 2 ELMOD2 Homo sapiens (Human) defense response to virus [GO:0051607]; regulation of defense response to virus [GO:0050688] membrane [GO:0016020] GTPase activator activity [GO:0005096] 0.96794 -2.8949 EKNINPEK 13.3109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.58131 0 Q8IZ83 A16A1_HUMAN Aldehyde dehydrogenase family 16 member A1 ALDH16A1 Homo sapiens (Human) membrane [GO:0016020] "oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]" 0.96215 -2.4643 FQAPGAR 0 0 0 0 0 0 0 0 0 0 10.8404 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IZA3 H18_HUMAN Histone H1.8 (Histone H1oo) (Oocyte-specific histone H1) (Oocyte-specific linker histone H1) (osH1) H1-8 H1FOO H1OO OSH1 Homo sapiens (Human) chromosome condensation [GO:0030261]; epigenetic regulation of gene expression [GO:0040029]; meiotic cell cycle [GO:0051321]; negative regulation of DNA recombination [GO:0045910]; nucleosome assembly [GO:0006334] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleosome [GO:0000786]; nucleus [GO:0005634] double-stranded DNA binding [GO:0003690]; nucleosomal DNA binding [GO:0031492]; structural constituent of chromatin [GO:0030527] 0.95858 -1.6785 AGQGPNTKAAAPAK 0 0 0 0 0 0 0 9.04685 0 0 0 9.39272 0 0 0 0 0 0 0 9.65397 9.30695 9.02431 9.75455 0 10.8872 0 0 Q8IZC4 RTKN2_HUMAN Rhotekin-2 (Pleckstrin homology domain-containing family K member 1) (PH domain-containing family K member 1) RTKN2 PLEKHK1 Homo sapiens (Human) hemopoiesis [GO:0030097]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886] 0.89883 -0.57868 FESKERTACK 0 0 0 0 0 0 0 0 0 9.5416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.73407 0 0 Q8IZC6 CORA1_HUMAN Collagen alpha-1(XXVII) chain COL27A1 KIAA1870 Homo sapiens (Human) collagen fibril organization [GO:0030199]; growth plate cartilage chondrocyte development [GO:0003431]; notochord development [GO:0030903]; skeletal system development [GO:0001501] collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrillar collagen trimer [GO:0005583] extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020]; metal ion binding [GO:0046872] 0.56089 0.52699 LEVGPACFL 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.62183 0 0 0 0 0 0 0 0 Q8IZC7 ZN101_HUMAN Zinc finger protein 101 (Zinc finger protein HZF12) ZNF101 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.95618 -1.5944 AFGWCSSLRR 0 0 0 0 0 0 0 0 0 8.487 0 0 0 0 0 0 0 0 0 0 9.94439 0 0 0 0 0 10.4739 Q8IZD2 KMT2E_HUMAN Inactive histone-lysine N-methyltransferase 2E (Inactive lysine N-methyltransferase 2E) (Myeloid/lymphoid or mixed-lineage leukemia protein 5) KMT2E MLL5 Homo sapiens (Human) cell cycle [GO:0007049]; chromatin organization [GO:0006325]; DNA methylation [GO:0006306]; erythrocyte differentiation [GO:0030218]; neutrophil activation [GO:0042119]; neutrophil mediated immunity [GO:0002446]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087] chromatin [GO:0000785]; cytoplasm [GO:0005737]; euchromatin [GO:0000791]; microtubule organizing center [GO:0005815]; nuclear body [GO:0016604]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; methylated histone binding [GO:0035064]; transcription coactivator activity [GO:0003713] 0.96257 -2.5008 FHGLEMCVDARTFGNEARFIR 0 0 0 0 0 0 0 10.5022 0 0 0 10.4877 10.1483 0 0 0 0 0 0 0 0 0 0 0 9.53986 0 0 Q8IZD4 DCP1B_HUMAN mRNA-decapping enzyme 1B (EC 3.6.1.62) DCP1B Homo sapiens (Human) "deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; deadenylation-independent decapping of nuclear-transcribed mRNA [GO:0031087]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of catalytic activity [GO:0043085]" cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleus [GO:0005634]; P-body [GO:0000932] 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity [GO:0140933]; enzyme activator activity [GO:0008047]; mRNA binding [GO:0003729] 0.87214 0.029252 LSIYGIWFYDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1006 Q8IZD9 DOCK3_HUMAN Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP) DOCK3 KIAA0299 MOCA Homo sapiens (Human) positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264] cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886] GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; SH3 domain binding [GO:0017124]; small GTPase binding [GO:0031267] 0.96396 -2.108 ENEFKSLWIER 0 0 10.6769 0 0 0 0 0 0 0 9.50821 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IZF0 NALCN_HUMAN Sodium leak channel NALCN (CanIon) (Sodium leak channel non-selective protein) (Voltage gated channel-like protein 1) NALCN VGCNL1 Homo sapiens (Human) "calcium ion transmembrane transport [GO:0070588]; monoatomic ion transmembrane transport [GO:0034220]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; potassium ion transmembrane transport [GO:0071805]; regulation of monoatomic ion transmembrane transport [GO:0034765]; regulation of resting membrane potential [GO:0060075]; sodium ion transmembrane transport [GO:0035725]" plasma membrane [GO:0005886] leak channel activity [GO:0022840]; monoatomic cation channel activity [GO:0005261]; sodium channel activity [GO:0005272]; voltage-gated monoatomic ion channel activity [GO:0005244]; voltage-gated sodium channel activity [GO:0005248] 0.95193 -1.3975 EDSEIKMIQEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.73921 0 0 0 10.8612 0 0 0 0 0 0 10.6303 Q8IZF6 AGRG4_HUMAN Adhesion G-protein coupled receptor G4 (G-protein coupled receptor 112) ADGRG4 GPR112 Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] membrane [GO:0016020] G protein-coupled receptor activity [GO:0004930] 0.96992 -5.9932 ADETASK 0 0 10.1938 10.872 11.2132 11.0899 0 0 10.8509 0 0 10.7498 8.5963 0 0 0 0 0 0 0 0 0 10.0388 0 0 0 10.6543 Q8IZH2 XRN1_HUMAN 5'-3' exoribonuclease 1 (EC 3.1.13.-) (Strand-exchange protein 1 homolog) XRN1 SEP1 Homo sapiens (Human) "cellular response to cycloheximide [GO:0071409]; cellular response to puromycin [GO:1905795]; histone mRNA catabolic process [GO:0071044]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of translation [GO:0017148]; nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process [GO:0000956]; response to testosterone [GO:0033574]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; rRNA catabolic process [GO:0016075]" cytosol [GO:0005829]; dendrite [GO:0030425]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; P-body [GO:0000932]; plasma membrane [GO:0005886]; synapse [GO:0045202] 5'-3' RNA exonuclease activity [GO:0004534]; G-quadruplex DNA binding [GO:0051880]; G-quadruplex RNA binding [GO:0002151]; RNA binding [GO:0003723]; telomerase RNA binding [GO:0070034] 0.96002 -1.811 AECWSQK 0 0 0 0 0 0 0 12.9519 0 9.69474 0 0 0 0 0 0 0 12.3889 0 0 0 0 0 0 0 0 0 Q8IZJ1 UNC5B_HUMAN Netrin receptor UNC5B (Protein unc-5 homolog 2) (Protein unc-5 homolog B) (p53-regulated receptor for death and life protein 1) (p53RDL1) UNC5B P53RDL1 UNC5H2 UNQ1883/PRO4326 Homo sapiens (Human) angiogenesis [GO:0001525]; anterior/posterior axon guidance [GO:0033564]; apoptotic process [GO:0006915]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068] membrane raft [GO:0045121]; plasma membrane [GO:0005886] netrin receptor activity [GO:0005042] 0.84628 0.15391 NKPVELR 0 0 0 11.4587 0 11.4697 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IZJ3 CPMD8_HUMAN C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8 CPAMD8 KIAA1283 Homo sapiens (Human) eye development [GO:0001654]; negative regulation of peptidase activity [GO:0010466] extracellular space [GO:0005615]; plasma membrane [GO:0005886] serine-type endopeptidase inhibitor activity [GO:0004867] 0.3463 0.76912 GSTDKAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.5343 0 0 0 0 0 0 0 0 Q8IZM8 ZN654_HUMAN Zinc finger protein 654 (Melanoma-associated antigen) ZNF654 Homo sapiens (Human) nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.9631 -2.1601 ESTEPKTCIESMEKK 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1222 0 0 0 0 0 0 0 0 0 0 10.0151 0 0 Q8IZP7 H6ST3_HUMAN Heparan-sulfate 6-O-sulfotransferase 3 (HS6ST-3) (EC 2.8.2.-) HS6ST3 Homo sapiens (Human) "heparan sulfate proteoglycan biosynthetic process, enzymatic modification [GO:0015015]" Golgi apparatus [GO:0005794]; membrane [GO:0016020] heparan sulfate 6-O-sulfotransferase activity [GO:0017095] 0.86289 0.080584 KCTCHRPGK 0 0 8.75205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IZP9 AGRG2_HUMAN Adhesion G-protein coupled receptor G2 (G-protein coupled receptor 64) (Human epididymis-specific protein 6) (He6) ADGRG2 GPR64 HE6 TM7LN2 Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186]; spermatogenesis [GO:0007283] apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930] 0.84379 0.15187 EDSCNGK 10.4102 10.2736 10.4597 0 0 0 0 0 0 0 0 0 0 0 9.61379 0 0 9.99421 0 0 0 0 0 0 0 9.86547 0 Q8IZQ1 WDFY3_HUMAN WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy) WDFY3 KIAA0993 Homo sapiens (Human) aggrephagy [GO:0035973] autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; inclusion body [GO:0016234]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; PML body [GO:0016605] 1-phosphatidylinositol binding [GO:0005545]; metal ion binding [GO:0046872] 0.92439 -1.0089 GYQLLAMLLK 11.0318 0 0 0 0 0 16.2613 11.0369 8.77864 0 0 0 0 0 9.94089 0 0 0 9.67902 0 0 9.5489 0 0 0 0 10.1109 Q8IZS6 DYLT2_HUMAN Dynein light chain Tctex-type protein 2 (T-complex testis-specific protein 3) (T-complex-associated testis-expressed protein 3) (Tcte-3) (Tctex1 domain-containing protein 3) DYNLT2 TCTE3 TCTEX1D3 Homo sapiens (Human) microtubule-based movement [GO:0007018] cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; membrane [GO:0016020]; microtubule [GO:0005874] dynein intermediate chain binding [GO:0045505] 0.91556 -0.77033 YKFIIKVLFIQK 0 11.7777 9.83118 9.91431 9.63134 9.85843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IZS8 CA2D3_HUMAN Voltage-dependent calcium channel subunit alpha-2/delta-3 (Voltage-gated calcium channel subunit alpha-2/delta-3) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-3; Voltage-dependent calcium channel subunit delta-3] CACNA2D3 Homo sapiens (Human) regulation of monoatomic ion transmembrane transport [GO:0034765] voltage-gated calcium channel complex [GO:0005891] metal ion binding [GO:0046872]; voltage-gated calcium channel activity [GO:0005245] 0.96898 -3.9759 IFTYLIGR 0 0 0 0 0 0 11.6268 8.35036 14.3081 0 0 0 0 12.9336 0 0 0 0 0 0 10.4312 0 0 0 9.53924 0 0 Q8IZT6 ASPM_HUMAN Abnormal spindle-like microcephaly-associated protein (Abnormal spindle protein homolog) (Asp homolog) ASPM MCPH5 Homo sapiens (Human) asymmetric cell division [GO:0008356]; cerebral cortex development [GO:0021987]; developmental growth [GO:0048589]; forebrain neuroblast division [GO:0021873]; maintenance of centrosome location [GO:0051661]; male gonad development [GO:0008584]; meiotic spindle assembly [GO:0090306]; negative regulation of asymmetric cell division [GO:0045769]; negative regulation of neuron differentiation [GO:0045665]; neuron migration [GO:0001764]; neuronal stem cell population maintenance [GO:0097150]; oogenesis [GO:0048477]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of neuroblast proliferation [GO:0002052]; regulation of meiotic cell cycle [GO:0051445]; spermatogenesis [GO:0007283]; spindle localization [GO:0051653]; spindle organization [GO:0007051] apical plasma membrane [GO:0016324]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; meiotic spindle [GO:0072687]; microtubule minus-end [GO:0036449]; midbody [GO:0030496]; mitotic spindle pole [GO:0097431]; nucleus [GO:0005634] calmodulin binding [GO:0005516] 0.96833 -9.1868 AACLIQAHYRGYKGR 0 0 0 9.79414 11.1339 0 0 0 0 0 0 10.4018 0 0 8.8895 0 9.61774 0 0 0 15.6762 0 0 0 0 0 11.4056 Q8IZT8 HS3S5_HUMAN Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (3-OST-5) (Heparan sulfate 3-O-sulfotransferase 5) (h3-OST-5) HS3ST5 3OST5 HS3OST5 Homo sapiens (Human) "heparan sulfate proteoglycan biosynthetic process, enzymatic modification [GO:0015015]; negative regulation of coagulation [GO:0050819]; protein sulfation [GO:0006477]; regulation of viral entry into host cell [GO:0046596]" Golgi membrane [GO:0000139]; membrane [GO:0016020] 3'-phosphoadenosine 5'-phosphosulfate binding [GO:0050656]; [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity [GO:0008467] 0.96092 -2.0114 IYKMNSSIK 0 0 0 0 12.4011 0 0 14.2169 0 0 0 0 12.9421 12.9336 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IZU1 FAM9A_HUMAN Protein FAM9A FAM9A Homo sapiens (Human) meiotic cell cycle [GO:0051321]; spermatid development [GO:0007286] nucleolus [GO:0005730]; synaptonemal complex [GO:0000795] 0.898 -0.56647 DNYCIISSSEESELDN 0 0 0 0 0 0 0 0 0 0 0 0 0 9.69133 0 0 0 10.1126 0 0 0 0 0 0 10.9669 0 0 Q8IZU2 WDR17_HUMAN WD repeat-containing protein 17 WDR17 Homo sapiens (Human) 0.8712 0.059976 DMIATGCEDTNVR 0 0 0 0 0 0 11.6573 0 0 0 0 12.1968 0 0 0 0 0 10.865 0 0 0 0 0 0 0 0 0 Q8IZU3 SYCP3_HUMAN Synaptonemal complex protein 3 (SCP-3) SYCP3 SCP3 Homo sapiens (Human) cell division [GO:0051301]; male meiosis I [GO:0007141]; meiotic cell cycle [GO:0051321]; sperm DNA condensation [GO:0035092]; spermatid development [GO:0007286] "chromosome, centromeric region [GO:0000775]; lateral element [GO:0000800]; nucleus [GO:0005634]; synaptonemal complex [GO:0000795]" DNA binding [GO:0003677] 0.4136 0.68587 KIMMETQQQEIASVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4756 0 0 0 0 0 0 0 0 0 Q8IZU8 DSEL_HUMAN Dermatan-sulfate epimerase-like protein (EC 5.1.-.-) DSEL C18orf4 NCAG1 Homo sapiens (Human) chondroitin sulfate metabolic process [GO:0030204]; dermatan sulfate biosynthetic process [GO:0030208]; dermatan sulfate metabolic process [GO:0030205] Golgi membrane [GO:0000139] chondroitin-glucuronate 5-epimerase activity [GO:0047757]; sulfotransferase activity [GO:0008146] 0.89717 -0.62902 LAQYFAMNK 0 0 0 0 0 0 9.35412 0 10.0101 0 0 0 9.2616 0 0 0 0 0 0 9.00099 0 0 0 10.4453 0 0 0 Q8IZU9 KIRR3_HUMAN Kin of IRRE-like protein 3 (Kin of irregular chiasm-like protein 3) (Nephrin-like protein 2) [Cleaved into: Processed kin of IRRE-like protein 3] KIRREL3 KIAA1867 NEPH2 UNQ5923/PRO4502/PRO19814 Homo sapiens (Human) cell-cell adhesion [GO:0098609]; glomerulus morphogenesis [GO:0072102]; hemopoiesis [GO:0030097]; hippocampus development [GO:0021766]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inter-male aggressive behavior [GO:0002121]; neuron migration [GO:0001764]; neuron projection morphogenesis [GO:0048812]; principal sensory nucleus of trigeminal nerve development [GO:0021740]; synapse assembly [GO:0007416] axon [GO:0030424]; cell-cell junction [GO:0005911]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; synaptic vesicle [GO:0008021] cell adhesion molecule binding [GO:0050839] 0.80096 0.2398 GEVINGATYSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5641 10.0356 0 0 Q8IZW8 TENS4_HUMAN Tensin-4 (C-terminal tensin-like protein) TNS4 CTEN PP14434 Homo sapiens (Human) protein localization [GO:0008104] cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925] actin binding [GO:0003779] 0.16774 0.97358 EQAIELLRK 0 0 0 0 0 0 9.54063 0 0 0 0 8.93517 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8IZX4 TAF1L_HUMAN Transcription initiation factor TFIID subunit 1-like (TAF(II)210) (TBP-associated factor 1-like) (TBP-associated factor 210 kDa) (Transcription initiation factor TFIID 210 kDa subunit) TAF1L Homo sapiens (Human) male meiotic nuclear division [GO:0007140]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA polymerase II preinitiation complex assembly [GO:0051123] nucleoplasm [GO:0005654]; transcription factor TFIID complex [GO:0005669] DNA binding [GO:0003677]; histone acetyltransferase activity [GO:0004402]; lysine-acetylated histone binding [GO:0070577]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II general transcription initiation factor binding [GO:0001091]; TBP-class protein binding [GO:0017025] 0.95462 -1.6248 FIQKFALFDEK 0 0 0 0 0 0 0 0 0 0 0 9.38344 0 0 0 0 10.3161 0 0 0 0 8.54971 0 0 0 0 0 Q8IZY2 ABCA7_HUMAN Phospholipid-transporting ATPase ABCA7 (EC 7.6.2.1) (ABCA-SSN) (ATP-binding cassette sub-family A member 7) (Autoantigen SS-N) (Macrophage ABC transporter) ABCA7 Homo sapiens (Human) amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta formation [GO:0034205]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; cholesterol efflux [GO:0033344]; high-density lipoprotein particle assembly [GO:0034380]; memory [GO:0007613]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of endocytosis [GO:0045806]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; peptide cross-linking [GO:0018149]; phagocytosis [GO:0006909]; phospholipid efflux [GO:0033700]; phospholipid translocation [GO:0045332]; plasma membrane raft organization [GO:0044857]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of engulfment of apoptotic cell [GO:1901076]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phospholipid efflux [GO:1902995]; positive regulation of protein localization to cell surface [GO:2000010]; protein localization to nucleus [GO:0034504]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of lipid metabolic process [GO:0019216]; visual learning [GO:0008542] cell junction [GO:0030054]; cell surface [GO:0009986]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; glial cell projection [GO:0097386]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587] ABC-type transporter activity [GO:0140359]; apolipoprotein A-I receptor activity [GO:0034188]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]; floppase activity [GO:0140328]; phosphatidylcholine floppase activity [GO:0090554]; phosphatidylserine floppase activity [GO:0090556]; phospholipid transporter activity [GO:0005548] 0.90259 -0.70107 DRFWDPGPAADPLTDLR 0 0 0 0 9.58508 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.82088 0 0 Q8J025 APCD1_HUMAN Protein APCDD1 (Adenomatosis polyposis coli down-regulated 1 protein) APCDD1 DRAPC1 FP7019 Homo sapiens (Human) astrocyte cell migration [GO:0043615]; hair follicle development [GO:0001942]; negative regulation of Wnt signaling pathway [GO:0030178]; regulation of odontogenesis of dentin-containing tooth [GO:0042487]; Wnt signaling pathway [GO:0016055] plasma membrane [GO:0005886] identical protein binding [GO:0042802]; Wnt-protein binding [GO:0017147] 0.47917 0.62503 HFIFHDNNNTWEGHYYHYSDPVCK 0 0 0 0 0 0 0 11.131 11.3246 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N0S6 CENPL_HUMAN Centromere protein L (CENP-L) (Interphase centromere complex protein 33) CENPL C1orf155 ICEN33 Homo sapiens (Human) "chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]" 0.82946 0.20426 GLAVEVGEDFNIK 0 0 0 0 10.428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N0U2 TMM61_HUMAN Transmembrane protein 61 TMEM61 Homo sapiens (Human) membrane [GO:0016020] 0.91409 -0.7814 ASIPGPPRWDPYHLSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6117 0 Q8N0U4 F185A_HUMAN Protein FAM185A FAM185A Homo sapiens (Human) 0.9164 -0.77441 TLKEWTLQVSPFGR 0 0 0 0 0 0 0 0 13.4164 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N0V4 LGI2_HUMAN Leucine-rich repeat LGI family member 2 (LGI1-like protein 2) (Leucine-rich glioma-inactivated protein 2) LGI2 KIAA1916 LGIL2 Homo sapiens (Human) inhibitory synapse assembly [GO:1904862] extracellular region [GO:0005576] 0.8477 0.1264 DNHYLALGSDYTFSQIYQWDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6917 0 Q8N0W5 IQCK_HUMAN IQ domain-containing protein K IQCK Homo sapiens (Human) 0.96201 -2.4536 IFWAKQEQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.95578 0 0 0 Q8N0X2 SPG16_HUMAN Sperm-associated antigen 16 protein (Pf20 protein homolog) SPAG16 PF20 Homo sapiens (Human) axoneme assembly [GO:0035082]; cerebrospinal fluid circulation [GO:0090660]; cilium assembly [GO:0060271]; mucociliary clearance [GO:0120197]; sperm axoneme assembly [GO:0007288] axonemal central apparatus [GO:1990716]; axoneme [GO:0005930]; extracellular region [GO:0005576]; sperm flagellum [GO:0036126] 0.96109 -2.0037 DILVSCGEDRLWK 0 9.45611 0 0 0 0 9.01633 0 9.01209 0 14.3983 16.0025 10.0065 8.87922 0 0 0 0 10.591 0 0 11.2448 0 0 0 0 0 Q8N0X7 SPART_HUMAN Spartin (Spastic paraplegia 20 protein) (Trans-activated by hepatitis C virus core protein 1) SPART KIAA0610 SPG20 TAHCCP1 Homo sapiens (Human) abscission [GO:0009838]; adipose tissue development [GO:0060612]; BMP signaling pathway [GO:0030509]; cell division [GO:0051301]; collateral sprouting in absence of injury [GO:0048669]; lipid droplet organization [GO:0034389]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of collateral sprouting in absence of injury [GO:0048698]; neuromuscular process [GO:0050905]; regulation of mitochondrial membrane potential [GO:0051881] cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; midbody [GO:0030496]; mitochondrial outer membrane [GO:0005741]; plasma membrane [GO:0005886]; synapse [GO:0045202] ubiquitin protein ligase binding [GO:0031625] 0.93172 -1.2556 IQPEEKPVEVSPAVTK 10.5783 0 0 0 0 0 0 9.60594 0 0 8.75522 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1519 Q8N0Y2 ZN444_HUMAN Zinc finger protein 444 (Endothelial zinc finger protein 2) (EZF-2) (Zinc finger and SCAN domain-containing protein 17) ZNF444 EZF2 ZSCAN17 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.84897 0.15618 EKPHACCECGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.41937 9.28529 0 0 0 0 0 0 0 0 0 0 Q8N0Z2 ABRA_HUMAN Actin-binding Rho-activating protein (Striated muscle activator of Rho-dependent signaling) (STARS) ABRA Homo sapiens (Human) positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein import into nucleus [GO:0006606]; transcription by RNA polymerase II [GO:0006366] actin cytoskeleton [GO:0015629]; plasma membrane [GO:0005886]; sarcomere [GO:0030017] actin binding [GO:0003779] 0.92626 -1.184 ESGEGPAKSALR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.60968 0 0 0 0 0 Q8N0Z3 SPICE_HUMAN Spindle and centriole-associated protein 1 (Coiled-coil domain-containing protein 52) (Spindle and centriole-associated protein) SPICE1 CCDC52 SPICE Homo sapiens (Human) cell division [GO:0051301]; metaphase plate congression [GO:0051310]; mitotic spindle assembly [GO:0090307]; regulation of centriole replication [GO:0046599] centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; spindle [GO:0005819] 0.90661 -0.71537 ALVHWELQEK 0 0 9.44969 0 0 0 10.996 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.53784 0 0 0 0 0 Q8N0Z6 TTC5_HUMAN Tetratricopeptide repeat protein 5 (TPR repeat protein 5) (Stress-responsive activator of p300) (Protein Strap) TTC5 Homo sapiens (Human) cellular response to starvation [GO:0009267]; DNA damage response [GO:0006974]; DNA repair [GO:0006281]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of transcription by RNA polymerase II [GO:0045944] cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; ribosome binding [GO:0043022] 0.92179 -1.123 KQQDVQKEMEK 10.809 0 10.7056 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9287 0 0 9.86048 0 0 0 0 0 0 0 Q8N103 TAGAP_HUMAN T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein) TAGAP TAGAP1 FKSG15 Homo sapiens (Human) regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] cytosol [GO:0005829] GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085] 0.96945 -3.1723 EVSPEPIVSTVARLK 0 0 0 0 0 0 0 0 0 8.81865 0 0 0 10.5402 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N118 CP4X1_HUMAN Cytochrome P450 4X1 (EC 1.14.14.-) (CYPIVX1) CYP4X1 UNQ1929/PRO4404 Homo sapiens (Human) lipid metabolic process [GO:0006629] endoplasmic reticulum membrane [GO:0005789] "anandamide 14,15 epoxidase activity [GO:0062189]; heme binding [GO:0020037]; iron ion binding [GO:0005506]" 0.96258 -2.5017 LEEIIEK 0 0 0 0 0 0 0 0 0 0 8.85106 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N122 RPTOR_HUMAN Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein) RPTOR KIAA1303 RAPTOR Homo sapiens (Human) cellular response to amino acid stimulus [GO:0071230]; cellular response to hypoxia [GO:0071456]; cellular response to leucine [GO:0071233]; cellular response to nutrient levels [GO:0031669]; cellular response to osmotic stress [GO:0071470]; cellular response to starvation [GO:0009267]; DNA damage response [GO:0006974]; negative regulation of autophagy [GO:0010507]; phosphorylation [GO:0016310]; positive regulation of cell growth [GO:0030307]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of glycolytic process [GO:0045821]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of pentose-phosphate shunt [GO:1905857]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of TOR signaling [GO:0032008]; positive regulation of transcription by RNA polymerase III [GO:0045945]; regulation of autophagy [GO:0010506]; regulation of cell growth [GO:0001558]; regulation of cell size [GO:0008361]; response to xenobiotic stimulus [GO:0009410]; social behavior [GO:0035176]; TOR signaling [GO:0031929]; TORC1 signaling [GO:0038202] cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; TORC1 complex [GO:0031931] 14-3-3 protein binding [GO:0071889]; protein kinase activator activity [GO:0030295]; protein kinase binding [GO:0019901]; protein serine/threonine kinase inhibitor activity [GO:0030291]; protein-containing complex binding [GO:0044877]; protein-macromolecule adaptor activity [GO:0030674]; RNA polymerase III type 1 promoter sequence-specific DNA binding [GO:0001002]; RNA polymerase III type 2 promoter sequence-specific DNA binding [GO:0001003]; RNA polymerase III type 3 promoter sequence-specific DNA binding [GO:0001006]; TFIIIC-class transcription factor complex binding [GO:0001156] 0.92989 -1.2394 IVRIWDTDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.167 0 0 0 0 0 0 0 0 Q8N135 LGI4_HUMAN Leucine-rich repeat LGI family member 4 (LGI1-like protein 3) (Leucine-rich glioma-inactivated protein 4) LGI4 LGIL3 UNQ6515/PRO21485 Homo sapiens (Human) adult locomotory behavior [GO:0008344]; glial cell proliferation [GO:0014009]; myelination in peripheral nervous system [GO:0022011]; neuron maturation [GO:0042551]; regulation of myelination [GO:0031641] extracellular region [GO:0005576]; extracellular space [GO:0005615] 0.87626 -0.0015198 YIGDSMVMR 9.79646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N137 CNTRB_HUMAN Centrobin (Centrosomal BRCA2-interacting protein) (LYST-interacting protein 8) CNTROB LIP8 PP1221 Homo sapiens (Human) centriole replication [GO:0007099]; centrosome separation [GO:0051299]; mitotic cytokinetic process [GO:1902410]; regulation of cilium assembly [GO:1902017] centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737] protein domain specific binding [GO:0019904] 0.88455 -0.14853 GLQEEHQAAELTR 14.7137 0 0 0 0 0 0 0 0 0 0 0 0 9.03897 0 0 0 0 0 0 10.7883 0 0 9.26334 0 0 10.4464 Q8N140 EID3_HUMAN EP300-interacting inhibitor of differentiation 3 (EID-3) (E1A-like inhibitor of differentiation 3) (EID-1-like inhibitor of differentiation 3) (Non-structural maintenance of chromosomes element 4 homolog B) (NS4EB) (Non-SMC element 4 homolog B) EID3 Homo sapiens (Human) DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; protein sumoylation [GO:0016925]; regulation of telomere maintenance [GO:0032204] "chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Smc5-Smc6 complex [GO:0030915]" 0.82114 0.21694 LLELTADEEK 0 0 0 0 0 0 9.53794 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N141 ZFP82_HUMAN Zinc finger protein 82 homolog (Zfp-82) (Zinc finger protein 545) ZFP82 KIAA1948 ZNF545 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.95464 -1.5749 ECWKAFSR 0 0 9.11964 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N143 BCL6B_HUMAN B-cell CLL/lymphoma 6 member B protein (Bcl6-associated zinc finger protein) (Zinc finger protein 62) BCL6B BAZF ZNF62 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of cytokine production [GO:0001817]; regulation of immune system process [GO:0002682] nucleus [GO:0005634] "DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96581 -2.3036 CQLCRSSFR 0 10.0449 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N145 LGI3_HUMAN Leucine-rich repeat LGI family member 3 (LGI1-like protein 4) (Leucine-rich glioma-inactivated protein 3) LGI3 LGIL4 UNQ8190/PRO23199 Homo sapiens (Human) exocytosis [GO:0006887]; regulation of exocytosis [GO:0017157] extracellular region [GO:0005576]; extracellular space [GO:0005615]; juxtaparanode region of axon [GO:0044224]; synaptic vesicle [GO:0008021] 0.93914 -1.3212 LQDIDPQRVR 0 0 0 0 0 0 0 0 0 0 0 8.98908 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N148 OR6V1_HUMAN Olfactory receptor 6V1 (Olfactory receptor OR7-3) OR6V1 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.82577 0.21284 TVLQGQMQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.63436 0 0 0 0 0 0 0 0 Q8N149 LIRA2_HUMAN Leukocyte immunoglobulin-like receptor subfamily A member 2 (CD85 antigen-like family member H) (Immunoglobulin-like transcript 1) (ILT-1) (Leukocyte immunoglobulin-like receptor 7) (LIR-7) (CD antigen CD85h) LILRA2 ILT1 LIR7 Homo sapiens (Human) cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; innate immune response [GO:0045087]; innate immune response activating cell surface receptor signaling pathway [GO:0002220]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; neutrophil activation involved in immune response [GO:0002283]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell activation [GO:0050867]; positive regulation of granulocyte colony-stimulating factor production [GO:0071657]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of tumor necrosis factor production [GO:0032760]; signal transduction [GO:0007165] extracellular region [GO:0005576]; plasma membrane [GO:0005886] antigen binding [GO:0003823]; IgM binding [GO:0001791]; inhibitory MHC class I receptor activity [GO:0032396]; signaling receptor activity [GO:0038023] 0.96173 -2.5872 LNSHSHAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.37317 0 0 0 0 10.4105 0 0 Q8N157 AHI1_HUMAN Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1) AHI1 Homo sapiens (Human) central nervous system development [GO:0007417]; cilium assembly [GO:0060271]; cloaca development [GO:0035844]; heart looping [GO:0001947]; hindbrain development [GO:0030902]; Kupffer's vesicle development [GO:0070121]; left/right axis specification [GO:0070986]; morphogenesis of a polarized epithelium [GO:0001738]; motile cilium assembly [GO:0044458]; negative regulation of apoptotic process [GO:0043066]; otic vesicle development [GO:0071599]; photoreceptor cell outer segment organization [GO:0035845]; positive regulation of polarized epithelial cell differentiation [GO:0030862]; positive regulation of receptor internalization [GO:0002092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pronephric duct morphogenesis [GO:0039023]; pronephric nephron tubule morphogenesis [GO:0039008]; protein localization [GO:0008104]; regulation of behavior [GO:0050795]; retina layer formation [GO:0010842]; specification of axis polarity [GO:0065001]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vesicle-mediated transport [GO:0016192] adherens junction [GO:0005912]; cell-cell junction [GO:0005911]; centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cilium [GO:0005929]; cytosol [GO:0005829]; MKS complex [GO:0036038]; non-motile cilium [GO:0097730] identical protein binding [GO:0042802] 0.92182 -1.1004 ELCGHLNIIYDLSWSK 0 0 0 8.68979 0 0 10.8254 0 10.8548 0 0 0 0 0 0 0 10.0501 0 0 0 0 0 0 0 0 0 0 Q8N158 GPC2_HUMAN Glypican-2 [Cleaved into: Secreted glypican-2] GPC2 Homo sapiens (Human) cell migration [GO:0016477]; neuron differentiation [GO:0030182]; positive regulation of neuron projection development [GO:0010976]; regulation of protein localization to membrane [GO:1905475]; regulation of signal transduction [GO:0009966]; smoothened signaling pathway [GO:0007224] cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; lysosomal lumen [GO:0043202]; plasma membrane [GO:0005886]; synapse [GO:0045202] 0.28377 0.82672 GGGGSAR 0 0 0 0 0 0 0 0 0 0 11.0898 0 0 0 0 0 0 0 0 0 0 0 9.82941 0 0 0 0 Q8N159 NAGS_HUMAN "N-acetylglutamate synthase, mitochondrial (EC 2.3.1.1) (Amino-acid acetyltransferase) [Cleaved into: N-acetylglutamate synthase long form; N-acetylglutamate synthase short form; N-acetylglutamate synthase conserved domain form]" NAGS Homo sapiens (Human) arginine biosynthetic process [GO:0006526]; glutamate metabolic process [GO:0006536]; urea cycle [GO:0000050] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] acetyl-CoA:L-glutamate N-acetyltransferase activity [GO:0004042]; methione N-acyltransferase activity [GO:0103045] 0.92239 -1.0857 GGTGGAR 0 0 0 0 0 0 0 0 0 0 9.90417 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.3718 Q8N163 CCAR2_HUMAN Cell cycle and apoptosis regulator protein 2 (Cell division cycle and apoptosis regulator protein 2) (DBIRD complex subunit KIAA1967) (Deleted in breast cancer gene 1 protein) (DBC-1) (DBC.1) (NET35) (p30 DBC) CCAR2 DBC1 KIAA1967 Homo sapiens (Human) cell cycle [GO:0007049]; DNA damage response [GO:0006974]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mRNA processing [GO:0006397]; negative regulation of catalytic activity [GO:0043086]; negative regulation of cell growth [GO:0030308]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of DNA damage checkpoint [GO:2000003]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-templated transcription elongation [GO:0032784]; regulation of protein deacetylation [GO:0090311]; regulation of protein stability [GO:0031647]; response to UV [GO:0009411]; rhythmic process [GO:0048511]; RNA splicing [GO:0008380]; Wnt signaling pathway [GO:0016055] chromatin [GO:0000785]; cytoplasm [GO:0005737]; DBIRD complex [GO:0044609]; mitochondrial matrix [GO:0005759]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819] adenyl-nucleotide exchange factor activity [GO:0000774]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; RNA binding [GO:0003723]; RNA polymerase II complex binding [GO:0000993]; unfolded protein binding [GO:0051082] 0.94078 -1.3097 FSATEVTNK 0 0 0 0 0 0 0 0 0 0 0 0 16.6408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N165 PDK1L_HUMAN Serine/threonine-protein kinase PDIK1L (EC 2.7.11.1) (PDLIM1-interacting kinase 1-like) PDIK1L CLIK1L Homo sapiens (Human) protein phosphorylation [GO:0006468] nucleoplasm [GO:0005654] ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.20642 0.91487 EFWALSSIK 0 0 15.2794 0 0 0 0 0 8.69766 0 0 0 10.0526 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N184 ZN567_HUMAN Zinc finger protein 567 ZNF567 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.9622 -2.4742 NLIVHQRTHKGENIEMQ 0 17.723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.96454 11.2939 0 0 0 0 12.1049 0 Q8N196 SIX5_HUMAN Homeobox protein SIX5 (DM locus-associated homeodomain protein) (Sine oculis homeobox homolog 5) SIX5 DMAHP Homo sapiens (Human) lens development in camera-type eye [GO:0002088]; Leydig cell proliferation [GO:0160024]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of skeletal muscle satellite cell proliferation [GO:1902723]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatid development [GO:0007286] chromatin [GO:0000785]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.83482 0.18614 GEYAELYR 0 0 0 0 0 0 0 0 9.11413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N1A0 KT222_HUMAN Keratin-like protein KRT222 (Keratin-222) (Keratin-222 pseudogene) KRT222 KA21 KRT222P Homo sapiens (Human) intermediate filament [GO:0005882] structural molecule activity [GO:0005198] 0.88491 -0.1288 HLLEKEEIRYYGCIQGGK 0 0 0 0 9.34769 0 0 0 0 9.46565 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N1B4 VPS52_HUMAN Vacuolar protein sorting-associated protein 52 homolog (SAC2 suppressor of actin mutations 2-like protein) VPS52 SACM2L Homo sapiens (Human) "ectodermal cell differentiation [GO:0010668]; embryonic ectodermal digestive tract development [GO:0048611]; endocytic recycling [GO:0032456]; Golgi to vacuole transport [GO:0006896]; lysosomal transport [GO:0007041]; protein targeting [GO:0006605]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle-mediated cholesterol transport [GO:0090119]" cytosol [GO:0005829]; EARP complex [GO:1990745]; endosome membrane [GO:0010008]; GARP complex [GO:0000938]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; trans-Golgi network membrane [GO:0032588] syntaxin binding [GO:0019905] 0.96276 -2.672 IREFILQKIYSFR 0 0 9.23379 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N1C3 GBRG1_HUMAN Gamma-aminobutyric acid receptor subunit gamma-1 (GABA(A) receptor subunit gamma-1) GABRG1 Homo sapiens (Human) "chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; nervous system process [GO:0050877]; regulation of postsynaptic membrane potential [GO:0060078]; signal transduction [GO:0007165]; synaptic transmission, GABAergic [GO:0051932]" chloride channel complex [GO:0034707]; dendrite membrane [GO:0032590]; GABA-A receptor complex [GO:1902711]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202] GABA receptor binding [GO:0050811]; GABA-A receptor activity [GO:0004890]; GABA-gated chloride ion channel activity [GO:0022851]; inhibitory extracellular ligand-gated monoatomic ion channel activity [GO:0005237] 0.91453 -0.82842 IHIRIAKIDSYSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.72161 8.82161 0 0 0 0 0 0 0 Q8N1D0 BWR1B_HUMAN Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene B protein (Organic cation transporter-like protein 2 antisense protein) (Solute carrier family 22 member 1-like antisense protein) (Solute carrier family 22 member 18 antisense protein) (p27-Beckwith-Wiedemann region 1 B) (p27-BWR1B) SLC22A18AS BWR1B BWSCR1B ORCTL2S SLC22A1LS Homo sapiens (Human) 0.91776 -0.86679 EARRQFCR 0 0 0 0 0 0 0 0 0 0 0 9.38368 0 0 0 9.38789 0 0 0 9.72999 0 0 0 0 0 0 0 Q8N1E2 LYG1_HUMAN Lysozyme g-like protein 1 (EC 3.2.1.-) LYG1 UNQ1939/PRO4422 Homo sapiens (Human) defense response to Gram-positive bacterium [GO:0050830]; peptidoglycan catabolic process [GO:0009253] extracellular region [GO:0005576] lysozyme activity [GO:0003796] 0.13274 1.0606 LAEIDMPYLLK 9.3468 15.4641 10.7264 8.38167 0 0 9.07609 15.0077 0 0 0 0 8.74268 0 0 0 0 0 12.6793 0 0 11.8445 0 11.7964 0 0 0 Q8N1F7 NUP93_HUMAN Nuclear pore complex protein Nup93 (93 kDa nucleoporin) (Nucleoporin Nup93) NUP93 KIAA0095 Homo sapiens (Human) nuclear envelope organization [GO:0006998]; nuclear pore complex assembly [GO:0051292]; nucleocytoplasmic transport [GO:0006913]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of SMAD protein signal transduction [GO:0060391]; protein import into nucleus [GO:0006606]; SMAD protein signal transduction [GO:0060395] centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear periphery [GO:0034399]; nuclear pore [GO:0005643] structural constituent of nuclear pore [GO:0017056] 0.89022 -0.4828 ALRNNTDPYKR 0 0 0 0 0 0 10.0077 0 0 0 9.75179 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N1F8 S11IP_HUMAN Serine/threonine-protein kinase 11-interacting protein (LKB1-interacting protein 1) STK11IP KIAA1898 LIP1 LKB1IP STK11IP1 Homo sapiens (Human) protein localization [GO:0008104] azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765] protein kinase binding [GO:0019901] 0.88303 -0.088249 ELSPLWLLAELR 13.5541 11.2893 11.2282 0 0 0 12.6321 10.6306 10.1929 11.4307 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N1G0 ZN687_HUMAN Zinc finger protein 687 ZNF687 KIAA1441 Homo sapiens (Human) cytosol [GO:0005829]; nucleoplasm [GO:0005654] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.96756 -3.7099 AGLGTGGQK 0 12.5773 12.5292 0 0 0 0 12.9097 12.9041 0 0 9.99492 9.39493 0 0 10.2921 0 0 0 0 0 0 0 0 0 0 0 Q8N1G1 REXO1_HUMAN RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin-A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1) REXO1 ELOABP1 KIAA1138 TCEB3BP1 Homo sapiens (Human) nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] exonuclease activity [GO:0004527]; nucleic acid binding [GO:0003676] 0.96971 -4.0273 AERPEGTKK 0 0 0 0 0 0 0 0 8.78692 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N1H7 S6OS1_HUMAN Protein SIX6OS1 (Six6 opposite strand transcript 1) SIX6OS1 C14orf39 Homo sapiens (Human) homologous chromosome pairing at meiosis [GO:0007129]; meiotic DNA double-strand break processing involved in reciprocal meiotic recombination [GO:0010705]; oogenesis [GO:0048477]; regulation of DNA-binding transcription factor activity [GO:0051090]; spermatogenesis [GO:0007283] central element [GO:0000801]; chromosome [GO:0005694] 0.91513 -0.80725 ALSETLEEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1694 0 0 0 0 0 11.4001 Q8N1I0 DOCK4_HUMAN Dedicator of cytokinesis protein 4 DOCK4 KIAA0716 Homo sapiens (Human) cell chemotaxis [GO:0060326]; negative regulation of vascular associated smooth muscle contraction [GO:1904694]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; small GTPase mediated signal transduction [GO:0007264] cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; stereocilium [GO:0032420]; stereocilium bundle [GO:0032421] GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; PDZ domain binding [GO:0030165]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; small GTPase binding [GO:0031267] 0.96779 -3.6658 CEENTNLQDTTR 0 0 9.42727 9.22795 0 9.72306 0 0 0 10.2297 0 0 0 0 0 0 0 9.47719 0 0 0 0 10.008 0 0 0 0 Q8N1K5 THMS1_HUMAN Protein THEMIS (Thymocyte-expressed molecule involved in selection) THEMIS C6orf190 C6orf207 Homo sapiens (Human) adaptive immune response [GO:0002250]; negative T cell selection [GO:0043383]; positive T cell selection [GO:0043368]; T cell receptor signaling pathway [GO:0050852] cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; nucleus [GO:0005634] 0.88546 -0.33698 EIVEWKIPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.82958 0 0 Q8N1N0 CLC4F_HUMAN C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13) CLEC4F CLECSF13 Homo sapiens (Human) endocytosis [GO:0006897] external side of plasma membrane [GO:0009897] carbohydrate binding [GO:0030246] 0.82185 0.21734 VYYWIGLTDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8507 Q8N1N2 DYNAP_HUMAN Dynactin-associated protein (Full) DYNAP C18orf26 Homo sapiens (Human) activation of protein kinase B activity [GO:0032148]; cellular response to ergosterol [GO:1901625]; positive regulation of cell population proliferation [GO:0008284]; regulation of apoptotic process [GO:0042981] Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886] 0.90532 -0.72858 EYCRNDWSMWK 0 0 0 0 0 0 0 0 0 0 0 0 9.02616 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N1N4 K2C78_HUMAN "Keratin, type II cytoskeletal 78 (Cytokeratin-78) (CK-78) (Keratin-5b) (Keratin-78) (K78) (Type-II keratin Kb40)" KRT78 K5B KB40 Homo sapiens (Human) keratinization [GO:0031424] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; keratin filament [GO:0045095] structural constituent of skin epidermis [GO:0030280] 0.96826 -3.6514 ARYEEIAR 0 0 0 0 0 0 0 0 0 0 9.14593 0 0 0 0 0 0 0 0 9.64877 0 0 0 0 0 0 0 Q8N1P7 CRBG2_HUMAN Beta/gamma crystallin domain-containing protein 2 (Absent in melanoma 1-like protein) CRYBG2 AIM1L Homo sapiens (Human) carbohydrate binding [GO:0030246] 0.92758 -1.2028 AGPSPSR 0 0 0 0 0 0 0 0 0 0 10.3867 0 0 8.02226 0 0 0 10.3098 0 8.15147 0 11.1463 0 0 0 0 0 Q8N1Q1 CAH13_HUMAN Carbonic anhydrase 13 (EC 4.2.1.1) (Carbonate dehydratase XIII) (Carbonic anhydrase XIII) (CA-XIII) CA13 Homo sapiens (Human) cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; myelin sheath [GO:0043209] carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270] 0.96116 -2.5603 YDPSSAK 0 0 0 0 0 0 0 0 0 0 0 8.94061 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N1V2 CFA52_HUMAN Cilia- and flagella-associated protein 52 (WD repeat-containing protein 16) (WD40-repeat protein up-regulated in HCC) CFAP52 WDR16 WDRPUH Homo sapiens (Human) establishment of left/right asymmetry [GO:0061966]; flagellated sperm motility [GO:0030317] 9+2 motile cilium [GO:0097729]; axonemal microtubule [GO:0005879]; axoneme [GO:0005930] 0.51799 0.59676 LLTDVGPAK 0 0 0 0 0 0 0 0 0 10.2234 0 0 0 0 0 0 0 0 0 0 0 0 0 11.8655 0 0 0 Q8N1V8 CJ085_HUMAN Uncharacterized protein encoded by LINC01561 LINC01561 C10orf85 Homo sapiens (Human) 0.9515 -1.3838 ASSELPNR 0 0 0 0 0 0 0 0 0 0 9.68396 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N1W1 ARG28_HUMAN Rho guanine nucleotide exchange factor 28 (190 kDa guanine nucleotide exchange factor) (p190-RhoGEF) (p190RhoGEF) (Rho guanine nucleotide exchange factor) ARHGEF28 KIAA1998 RGNEF Homo sapiens (Human) cell differentiation [GO:0030154]; cell morphogenesis [GO:0000902]; ephrin receptor signaling pathway [GO:0048013]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056] cytosol [GO:0005829]; plasma membrane [GO:0005886] guanyl-nucleotide exchange factor activity [GO:0005085]; metal ion binding [GO:0046872]; RNA binding [GO:0003723] 0.9548 -1.6216 GELDLQLQEYQHSLER 9.65431 10.4345 0 0 0 0 0 0 0 0 0 0 0 0 12.9639 0 0 0 0 0 0 0 0 0 0 0 0 Q8N1W2 ZN710_HUMAN Zinc finger protein 710 ZNF710 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.8971 -0.67188 EFTLQANMKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4697 0 0 0 Q8N1Y9 YI025_HUMAN Putative uncharacterized protein FLJ37218 Homo sapiens (Human) membrane [GO:0016020] 0.96344 -2.2402 CCLGCRASTR 8.31234 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0962 0 Q8N201 INT1_HUMAN Integrator complex subunit 1 (Int1) INTS1 KIAA1440 UNQ1821/PRO3434 Homo sapiens (Human) inner cell mass cell proliferation [GO:0001833]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; regulation of transcription elongation by RNA polymerase II [GO:0034243]; snRNA processing [GO:0016180]; U2 snRNA 3'-end processing [GO:0034474] integrator complex [GO:0032039]; membrane [GO:0016020]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.96971 -3.1206 EVRLLAVQK 0 0 0 0 0 11.2354 0 0 0 8.88176 0 0 10.1193 10.0787 10.2131 0 12.3961 11.9402 0 0 0 0 11.1945 0 0 0 0 Q8N239 KLH34_HUMAN Kelch-like protein 34 KLHL34 Homo sapiens (Human) extracellular space [GO:0005615] 0.92642 -1.1856 EVVIEEVAAPQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.52101 0 0 0 0 0 0 0 0 0 0 10.0967 Q8N283 ANR35_HUMAN Ankyrin repeat domain-containing protein 35 ANKRD35 Homo sapiens (Human) actin binding [GO:0003779] 0.97031 -3.2426 GRSEQFEKTAELLK 0 0 0 0 0 0 0 0 0 0 0 0 10.1343 0 0 0 0 0 0 0 0 0 0 10.0041 0 0 0 Q8N2C7 UNC80_HUMAN Protein unc-80 homolog UNC80 C2orf21 KIAA1843 Homo sapiens (Human) monoatomic cation homeostasis [GO:0055080] axon [GO:0030424]; cation channel complex [GO:0034703]; plasma membrane [GO:0005886] monoatomic cation channel activity [GO:0005261] 0.96235 -2.5389 EDFPLSHVISPFTNQER 0 0 10.2538 9.80579 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.55209 0 0 0 10.1793 0 Q8N2E2 VWDE_HUMAN von Willebrand factor D and EGF domain-containing protein VWDE Homo sapiens (Human) anatomical structure development [GO:0048856] cell surface [GO:0009986]; extracellular region [GO:0005576] signaling receptor binding [GO:0005102] 0.88581 -0.3665 DCCLFQIPVSVR 9.69801 0 0 0 0 0 8.76467 0 0 0 0 0 0 9.92643 9.70183 0 0 0 0 0 0 0 0 0 0 0 0 Q8N2I2 ZN619_HUMAN Zinc finger protein 619 ZNF619 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.93188 -1.2524 TAQLNISKESESHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.76451 0 0 0 0 0 0 0 Q8N2K0 ABD12_HUMAN Lysophosphatidylserine lipase ABHD12 (EC 3.1.-.-) (2-arachidonoylglycerol hydrolase ABHD12) (Abhydrolase domain-containing protein 12) (hABHD12) (Monoacylglycerol lipase ABHD12) (EC 3.1.1.23) (Oxidized phosphatidylserine lipase ABHD12) (EC 3.1.-.-) ABHD12 C20orf22 Homo sapiens (Human) acylglycerol catabolic process [GO:0046464]; adult walking behavior [GO:0007628]; arachidonic acid metabolic process [GO:0019369]; glycerophospholipid catabolic process [GO:0046475]; monoacylglycerol catabolic process [GO:0052651]; phosphatidylserine catabolic process [GO:0006660]; phospholipid catabolic process [GO:0009395]; protein depalmitoylation [GO:0002084]; regulation of inflammatory response [GO:0050727]; response to auditory stimulus [GO:0010996] AMPA glutamate receptor complex [GO:0032281]; dendrite cytoplasm [GO:0032839]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886] acylglycerol lipase activity [GO:0047372]; lysophospholipase activity [GO:0004622]; palmitoyl-(protein) hydrolase activity [GO:0008474]; phospholipase activity [GO:0004620] 0.53631 0.58215 CAADAGMKR 0 0 0 0 0 0 0 0 0 0 10.1041 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N2M8 CLASR_HUMAN "CLK4-associating serine/arginine rich protein (Splicing factor, arginine/serine-rich 16) (Suppressor of white-apricot homolog 2)" CLASRP SFRS16 SWAP2 UNQ2428/PRO4988 Homo sapiens (Human) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] nucleoplasm [GO:0005654] 0.96368 -2.6451 ALEEEKAMYSGR 0 0 0 0 0 0 0 0 0 0 0 0 11.5944 0 0 0 0 9.38638 0 0 0 0 9.25781 0 0 0 8.96959 Q8N2N9 AN36B_HUMAN Ankyrin repeat domain-containing protein 36B (CLL-associated antigen KW-1) ANKRD36B Homo sapiens (Human) identical protein binding [GO:0042802] 0.95501 -1.5624 CELNLCDREDR 0 0 0 0 0 0 11.3787 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N2R0 OSR2_HUMAN Protein odd-skipped-related 2 OSR2 Homo sapiens (Human) bone morphogenesis [GO:0060349]; cell differentiation [GO:0030154]; chondrocyte differentiation [GO:0002062]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic skeletal joint development [GO:0072498]; embryonic skeletal joint morphogenesis [GO:0060272]; embryonic skeletal limb joint morphogenesis [GO:0036023]; embryonic skeletal system morphogenesis [GO:0048704]; eyelid development in camera-type eye [GO:0061029]; head development [GO:0060322]; mesonephros development [GO:0001823]; metanephros development [GO:0001656]; middle ear morphogenesis [GO:0042474]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; osteoblast proliferation [GO:0033687]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of gene expression [GO:0010628]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; roof of mouth development [GO:0060021]; stem cell proliferation [GO:0072089]; urogenital system development [GO:0001655] nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96771 -2.9032 FCGRHFTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.40945 0 0 Q8N2R8 FA43A_HUMAN Protein FAM43A FAM43A PP7298 Homo sapiens (Human) 0.95897 -1.7161 VGSMFRSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.31517 0 0 Q8N2S1 LTBP4_HUMAN Latent-transforming growth factor beta-binding protein 4 (LTBP-4) LTBP4 Homo sapiens (Human) elastic fiber assembly [GO:0048251]; hormone secretion [GO:0046879]; protein folding [GO:0006457]; regulation of cell growth [GO:0001558]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; transforming growth factor beta receptor signaling pathway [GO:0007179] collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; microfibril [GO:0001527] calcium ion binding [GO:0005509]; glycosaminoglycan binding [GO:0005539]; integrin binding [GO:0005178]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor activity [GO:0005024] 0.89774 -0.54997 GAGLAWGVHDCQLCSER 0 0 0 0 9.23522 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N2W9 PIAS4_HUMAN E3 SUMO-protein ligase PIAS4 (EC 2.3.2.27) (PIASy) (Protein inhibitor of activated STAT protein 4) (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma) PIAS4 PIASG Homo sapiens (Human) central nervous system development [GO:0007417]; double-strand break repair [GO:0006302]; hair follicle development [GO:0001942]; limb epidermis development [GO:0060887]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein localization to chromatin [GO:0120186]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902231]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein sumoylation [GO:0033235]; protein sumoylation [GO:0016925]; regulation of transcription by RNA polymerase II [GO:0006357]; vitamin D metabolic process [GO:0042359]; Wnt signaling pathway [GO:0016055] cytoplasm [GO:0005737]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transferase complex [GO:1990234] DNA binding [GO:0003677]; molecular function inhibitor activity [GO:0140678]; SUMO ligase activity [GO:0061665]; SUMO transferase activity [GO:0019789]; transcription coregulator activity [GO:0003712]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270] 0.87142 0.062929 LQESPCIFALTPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.96171 0 0 0 0 0 0 0 0 0 0 0 0 Q8N2X6 EXAS1_HUMAN Uncharacterized protein EXOC3-AS1 (EXOC3 antisense RNA 1) (EXOC3 antisense gene protein 1) EXOC3-AS1 C5orf55 Homo sapiens (Human) extracellular region [GO:0005576] 0.84943 0.15495 TQPLQER 0 0 0 0 0 0 0 0 0 0 8.98513 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N2Y8 RUSC2_HUMAN AP-4 complex accessory subunit RUSC2 (Interacting protein of Rab1) (Iporin) (RUN and SH3 domain-containing protein 2) RUSC2 KIAA0375 Homo sapiens (Human) cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062] small GTPase binding [GO:0031267] 0.079612 1.2396 AGGDWLR 0 0 0 0 0 0 10.0006 0 0 0 0 0 9.13319 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N2Z9 CENPS_HUMAN Centromere protein S (CENP-S) (Apoptosis-inducing TAF9-like domain-containing protein 1) (FANCM-associated histone fold protein 1) (FANCM-interacting histone fold protein 1) (Fanconi anemia-associated polypeptide of 16 kDa) CENPS APITD1 FAAP16 MHF1 Homo sapiens (Human) cell division [GO:0051301]; DNA damage response [GO:0006974]; DNA repair [GO:0006281]; interstrand cross-link repair [GO:0036297]; positive regulation of protein ubiquitination [GO:0031398]; replication fork processing [GO:0031297]; resolution of meiotic recombination intermediates [GO:0000712] chromatin [GO:0000785]; cytosol [GO:0005829]; FANCM-MHF complex [GO:0071821]; Fanconi anaemia nuclear complex [GO:0043240]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982] 0.18341 0.95401 KSEDGSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.81952 0 8.88347 0 0 0 0 0 Q8N307 MUC20_HUMAN Mucin-20 (MUC-20) MUC20 KIAA1359 UNQ2782/PRO7170 Homo sapiens (Human) hepatocyte growth factor receptor signaling pathway [GO:0048012] apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886] identical protein binding [GO:0042802] 0.9471 -1.357 ISPARETR 0 0 0 0 0 0 0 0 8.82435 0 0 0 0 0 0 0 0 10.7458 0 0 0 0 0 0 0 0 0 Q8N309 LRC43_HUMAN Leucine-rich repeat-containing protein 43 LRRC43 Homo sapiens (Human) axoneme assembly [GO:0035082] axoneme [GO:0005930] dynein complex binding [GO:0070840] 0.96157 -2.5936 GEKEPAKEWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9883 9.65037 0 0 0 0 0 0 Q8N323 NXPE1_HUMAN NXPE family member 1 (Protein FAM55A) NXPE1 FAM55A Homo sapiens (Human) extracellular region [GO:0005576] 0.88498 -0.12998 MSSNTMLQK 0 0 0 0 0 0 0 0 9.21718 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N335 GPD1L_HUMAN Glycerol-3-phosphate dehydrogenase 1-like protein (GPD1-L) (EC 1.1.1.8) GPD1L KIAA0089 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate catabolic process [GO:0046168]; NAD metabolic process [GO:0019674]; NADH metabolic process [GO:0006734]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of protein kinase C signaling [GO:0090038]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of sodium ion transport [GO:0010765]; regulation of heart rate [GO:0002027]; regulation of sodium ion transmembrane transporter activity [GO:2000649]; regulation of ventricular cardiac muscle cell membrane depolarization [GO:0060373]; ventricular cardiac muscle cell action potential [GO:0086005] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glycerol-3-phosphate dehydrogenase complex [GO:0009331]; plasma membrane [GO:0005886] glycerol-3-phosphate dehydrogenase [NAD(P)+] activity [GO:0047952]; NAD binding [GO:0051287]; protein homodimerization activity [GO:0042803]; sodium channel regulator activity [GO:0017080]; transmembrane transporter binding [GO:0044325] 0.92176 -1.1039 MAAAPLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.01304 9.22489 0 Q8N350 CBARP_HUMAN Voltage-dependent calcium channel beta subunit-associated regulatory protein CBARP C19orf26 Homo sapiens (Human) negative regulation of calcium ion transmembrane transport [GO:1903170]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of voltage-gated calcium channel activity [GO:1901386] growth cone [GO:0030426]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; synaptic vesicle membrane [GO:0030672] transmembrane transporter binding [GO:0044325] 0.96365 -2.2021 ATLAIFQPPGKALTGR 0 0 0 0 0 0 0 0 0 0 0 11.3792 0 0 0 0 10.6957 9.64633 0 0 0 0 0 0 0 0 0 Q8N393 ZN786_HUMAN Zinc finger protein 786 ZNF786 Homo sapiens (Human) nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96935 -7.1623 AWEKFNK 0 0 0 0 0 0 0 10.765 0 0 8.61405 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.98556 Q8N394 TMTC2_HUMAN Protein O-mannosyl-transferase TMTC2 (EC 2.4.1.109) (Transmembrane and TPR repeat-containing protein 2) TMTC2 Homo sapiens (Human) calcium ion homeostasis [GO:0055074]; protein O-linked mannosylation [GO:0035269] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789] dolichyl-phosphate-mannose-protein mannosyltransferase activity [GO:0004169]; mannosyltransferase activity [GO:0000030] 0.88244 -0.078058 NGDWQNEEMLYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.77075 0 0 0 0 Q8N398 VW5B2_HUMAN von Willebrand factor A domain-containing protein 5B2 VWA5B2 Homo sapiens (Human) 0.56318 0.51371 GHARRCWLR 0 0 0 0 0 0 8.74137 9.51155 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N3A8 PARP8_HUMAN Protein mono-ADP-ribosyltransferase PARP8 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 16) (ARTD16) (Poly [ADP-ribose] polymerase 8) (PARP-8) PARP8 Homo sapiens (Human) endoplasmic reticulum unfolded protein response [GO:0030968]; protein auto-ADP-ribosylation [GO:0070213] endoplasmic reticulum tubular network [GO:0071782]; nuclear envelope [GO:0005635] kinase binding [GO:0019900]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+- protein-cysteine ADP-ribosyltransferase activity [GO:0140803]; NAD+-protein ADP-ribosyltransferase activity [GO:1990404]; nucleotidyltransferase activity [GO:0016779]; protein serine/threonine kinase activator activity [GO:0043539] 0.89911 -0.57233 EKSNCLHNK 0 0 0 0 0 0 0 0 0 0 0 0 10.3372 0 0 0 10.6014 0 8.83298 0 0 0 0 0 0 0 0 Q8N3C0 ASCC3_HUMAN "Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12) (ASC-1 complex subunit p200) (ASC1p200) (Helicase, ATP binding 1) (Trip4 complex subunit p200)" ASCC3 HELIC1 RQT2 Homo sapiens (Human) cell population proliferation [GO:0008283]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA duplex unwinding [GO:0032508]; rescue of stalled ribosome [GO:0072344]; ribosome disassembly [GO:0032790]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] activating signal cointegrator 1 complex [GO:0099053]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; DNA repair complex [GO:1990391]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; RNA binding [GO:0003723] 0.96884 -3.8747 DLADWLNIK 10.7738 0 0 10.5826 10.4977 0 10.9191 10.8223 0 0 0 0 0 0 0 0 0 13.3666 10.0039 0 0 0 9.0927 0 8.47163 0 0 Q8N3D4 EH1L1_HUMAN EH domain-binding protein 1-like protein 1 EHBP1L1 Homo sapiens (Human) endosome [GO:0005768]; membrane [GO:0016020] 0.15358 1.016 AQEAEAGVLGNEK 0 0 0 0 0 0 0 0 0 0 9.69971 0 0 0 0 9.7817 0 0 0 0 0 0 0 0 0 0 10.6151 Q8N3E9 PLCD3_HUMAN "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 (EC 3.1.4.11) (Phosphoinositide phospholipase C-delta-3) (Phospholipase C-delta-3) (PLC-delta-3)" PLCD3 KIAA1964 Homo sapiens (Human) angiogenesis [GO:0001525]; intracellular signal transduction [GO:0035556]; labyrinthine layer blood vessel development [GO:0060716]; lipid catabolic process [GO:0016042]; regulation of cell population proliferation [GO:0042127] cleavage furrow [GO:0032154]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] metal ion binding [GO:0046872]; phosphatidylinositol phospholipase C activity [GO:0004435] 0.88326 -0.037973 ALSDREEEEEDDEEEEEEVEAAAQR 0 0 0 0 0 0 0 0 0 9.90298 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8414 Q8N3F8 MILK1_HUMAN MICAL-like protein 1 (Molecule interacting with Rab13) (MIRab13) MICALL1 KIAA1668 MIRAB13 Homo sapiens (Human) endocytic recycling [GO:0032456]; endocytosis [GO:0006897]; neuron projection development [GO:0031175]; plasma membrane tubulation [GO:0097320]; protein localization to endosome [GO:0036010]; protein targeting to membrane [GO:0006612]; receptor-mediated endocytosis [GO:0006898]; slow endocytic recycling [GO:0032458] extrinsic component of membrane [GO:0019898]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; recycling endosome membrane [GO:0055038] cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; phosphatidic acid binding [GO:0070300]; small GTPase binding [GO:0031267] 0.96929 -4.5764 EAEPEGK 0 0 0 0 0 0 10.128 0 9.11236 10.7351 10.9009 0 10.2636 0 0 0 0 0 0 8.64767 0 0 0 0 0 0 0 Q8N3G9 TM130_HUMAN Transmembrane protein 130 TMEM130 UNQ719/PRO1383 Homo sapiens (Human) Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139] 0.96139 -2.5603 GLSSTIR 0 0 0 0 0 0 0 0 0 0 0 0 8.99738 0 9.01606 0 0 0 0 0 0 0 0 0 0 0 0 Q8N3J5 PPM1K_HUMAN "Protein phosphatase 1K, mitochondrial (EC 3.1.3.16) (PP2C domain-containing protein phosphatase 1K) (PP2C-like mitochondrial protein) (PP2C-type mitochondrial phosphoprotein phosphatase) (PTMP) (Protein phosphatase 2C isoform kappa) (PP2C-kappa)" PPM1K PP2CM Homo sapiens (Human) peptidyl-threonine dephosphorylation [GO:0035970] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] metal ion binding [GO:0046872]; myosin phosphatase activity [GO:0017018]; protein serine/threonine phosphatase activity [GO:0004722] 0.63032 0.40772 LTIDHTPER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0153 9.32957 0 0 0 0 Q8N3J6 CADM2_HUMAN Cell adhesion molecule 2 (Immunoglobulin superfamily member 4D) (IgSF4D) (Nectin-like protein 3) (NECL-3) (Synaptic cell adhesion molecule 2) (SynCAM 2) CADM2 IGSF4D NECL3 Homo sapiens (Human) brain development [GO:0007420]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] axon [GO:0030424]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; synapse [GO:0045202] 0.93221 -1.286 YLKEEDANRK 0 0 0 0 0 0 0 0 12.2619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N3K9 CMYA5_HUMAN Cardiomyopathy-associated protein 5 (Dystrobrevin-binding protein 2) (Genethonin-3) (Myospryn) (SPRY domain-containing protein 2) (Tripartite motif-containing protein 76) CMYA5 C5orf10 DTNBP2 SPRYD2 TRIM76 Homo sapiens (Human) cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; M band [GO:0031430]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; sarcoplasmic reticulum [GO:0016529] 0.88413 -0.14435 EKSYTGIYDK 0 10.8312 0 0 0 0 0 0 0 0 9.99548 0 0 0 0 0 0 9.51033 0 0 0 0 0 10.7703 0 0 8.9747 Q8N3L3 TXLNB_HUMAN Beta-taxilin (Muscle-derived protein 77) (hMDP77) TXLNB C6orf198 MDP77 Homo sapiens (Human) cytoplasm [GO:0005737] syntaxin binding [GO:0019905] 0.84292 0.15123 DQLQGEHSR 0 0 0 0 0 0 0 0 11.5155 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N3P4 VPS8_HUMAN Vacuolar protein sorting-associated protein 8 homolog VPS8 KIAA0804 Homo sapiens (Human) endosomal vesicle fusion [GO:0034058]; protein targeting to vacuole [GO:0006623]; regulation of SNARE complex assembly [GO:0035542] CORVET complex [GO:0033263]; early endosome [GO:0005769]; HOPS complex [GO:0030897]; late endosome [GO:0005770] metal ion binding [GO:0046872] 0.89616 -0.54274 DLIVHFQDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.82606 10.4502 0 Q8N3R3 TCAIM_HUMAN "T-cell activation inhibitor, mitochondrial (Tolerance associated gene-1 protein) (TOAG-1)" TCAIM C3orf23 TOAG1 Homo sapiens (Human) mitochondrion [GO:0005739] 0.91655 -0.77433 LKDELSHQLQLSDIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8691 0 0 0 0 0 0 Q8N3R9 PALS1_HUMAN "Protein PALS1 (MAGUK p55 subfamily member 5) (Membrane protein, palmitoylated 5) (Protein associated with Lin-7 1)" PALS1 MPP5 Homo sapiens (Human) central nervous system neuron development [GO:0021954]; cerebral cortex development [GO:0021987]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; establishment or maintenance of polarity of embryonic epithelium [GO:0016332]; gene expression [GO:0010467]; generation of neurons [GO:0048699]; morphogenesis of an epithelial sheet [GO:0002011]; myelin assembly [GO:0032288]; peripheral nervous system myelin maintenance [GO:0032287]; protein localization to myelin sheath abaxonal region [GO:0035750]; protein localization to plasma membrane [GO:0072659]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015] adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical plasma membrane [GO:0016324]; axon [GO:0030424]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; lateral loop [GO:0043219]; myelin sheath adaxonal region [GO:0035749]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schmidt-Lanterman incisure [GO:0043220] ATP binding [GO:0005524]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904] 0.95805 -1.6732 DRFASAVPHTTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0715 0 0 0 9.26681 Q8N3T1 GLT15_HUMAN Polypeptide N-acetylgalactosaminyltransferase 15 (EC 2.4.1.41) (Polypeptide GalNAc transferase-like protein 2) (GalNAc-T-like protein 2) (pp-GaNTase-like protein 2) (Polypeptide N-acetylgalactosaminyltransferase-like protein 2) (Protein-UDP acetylgalactosaminyltransferase-like protein 2) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 2) GALNT15 GALNTL2 UNQ770/PRO1564 Homo sapiens (Human) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; transport vesicle [GO:0030133] carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; polypeptide N-acetylgalactosaminyltransferase activity [GO:0004653] 0.83599 0.19271 SPVVPGEVVAMDR 0 0 0 0 0 0 0 0 0 0 9.57716 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N3T6 T132C_HUMAN Transmembrane protein 132C TMEM132C Homo sapiens (Human) membrane [GO:0016020] 0.96942 -4.8888 NHASDRR 0 0 0 0 0 0 8.73512 0 0 9.26092 0 0 9.96838 0 0 0 0 0 0 0 0 0 0 0 10.3291 0 0 Q8N3U4 STAG2_HUMAN Cohesin subunit SA-2 (SCC3 homolog 2) (Stromal antigen 2) STAG2 SA2 Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic sister chromatid cohesion [GO:0034087]; meiotic cell cycle [GO:0051321]; mitotic spindle assembly [GO:0090307]; sister chromatid cohesion [GO:0007062] "chromatin [GO:0000785]; chromosome [GO:0005694]; chromosome, centromeric region [GO:0000775]; cohesin complex [GO:0008278]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; membrane [GO:0016020]; mitotic spindle pole [GO:0097431]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]" chromatin binding [GO:0003682] 0.96807 -2.9149 DPEEDGMMK 0 0 9.28281 0 0 0 0 0 10.0182 0 0 0 10.0909 0 0 10.2186 9.75881 0 0 9.56554 0 0 0 9.28316 0 0 11.2003 Q8N3V7 SYNPO_HUMAN Synaptopodin SYNPO KIAA1029 Homo sapiens (Human) modification of dendritic spine [GO:0098886]; positive regulation of actin filament bundle assembly [GO:0032233]; regulation of stress fiber assembly [GO:0051492]; spine apparatus assembly [GO:1905355] actin cytoskeleton [GO:0015629]; bicellular tight junction [GO:0005923]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; spine apparatus [GO:0097444]; stress fiber [GO:0001725]; Z disc [GO:0030018] actin binding [GO:0003779] 0.92225 -1.0977 STSLTEKDLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.48718 0 9.84911 0 0 0 0 Q8N3X1 FNBP4_HUMAN Formin-binding protein 4 (Formin-binding protein 30) FNBP4 FBP30 KIAA1014 Homo sapiens (Human) nucleoplasm [GO:0005654] 0.95162 -1.3981 IDENSDKEMEVEESPEKIK 0 0 0 0 0 0 9.76595 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N3X6 LCORL_HUMAN Ligand-dependent nuclear receptor corepressor-like protein (LCoR-like protein) LCORL Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] DNA binding [GO:0003677]; histone methyltransferase binding [GO:1990226] 0.91155 -0.75145 DFHDSYSYKDSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.79526 0 0 0 0 0 Q8N3Y7 RDHE2_HUMAN Epidermal retinol dehydrogenase 2 (EPHD-2) (RDH-E2) (EC 1.1.1.105) (Retinal short-chain dehydrogenase reductase 2) (retSDR2) (Short-chain dehydrogenase/reductase family 16C member 5) SDR16C5 RDHE2 Homo sapiens (Human) "keratinocyte proliferation [GO:0043616]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription by RNA polymerase II [GO:0000122]; retinal metabolic process [GO:0042574]; retinol metabolic process [GO:0042572]" endoplasmic reticulum membrane [GO:0005789]; lipid droplet [GO:0005811]; nucleus [GO:0005634]; transcription repressor complex [GO:0017053] DNA-binding transcription factor binding [GO:0140297]; NAD-retinol dehydrogenase activity [GO:0004745]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription corepressor activity [GO:0003714] 0.15646 1.0101 LLALQFAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.73434 0 0 9.20107 11.1081 Q8N3Z3 GTPB8_HUMAN GTP-binding protein 8 GTPBP8 Homo sapiens (Human) mitochondrion [GO:0005739] GTP binding [GO:0005525]; metal ion binding [GO:0046872] 0.9554 -1.5518 IDHAPDLPRPEVCFIGRSNVGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.73688 0 10.2099 0 0 0 Q8N3Z6 ZCHC7_HUMAN Zinc finger CCHC domain-containing protein 7 (TRAMP-like complex RNA-binding factor ZCCHC7) ZCCHC7 HSPC086 Homo sapiens (Human) ncRNA polyadenylation [GO:0043629]; nuclear mRNA surveillance of mRNA 3'-end processing [GO:0071031]; nuclear polyadenylation-dependent CUT catabolic process [GO:0071039]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent snoRNA catabolic process [GO:0071036]; nuclear polyadenylation-dependent snRNA catabolic process [GO:0071037]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038] cytosol [GO:0005829]; nucleolus [GO:0005730]; TRAMP complex [GO:0031499] RNA binding [GO:0003723]; zinc ion binding [GO:0008270] 0.94396 -1.3352 HREVDEDFPRGPK 0 0 0 0 0 0 0 0 9.15843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N402 YV020_HUMAN Putative uncharacterized protein LOC388882 Homo sapiens (Human) 0.36967 0.73334 RYSLYTNQHWR 11.0664 0 0 0 0 0 10.4235 0 10.9558 10.5175 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N412 STPG2_HUMAN Sperm-tail PG-rich repeat-containing protein 2 STPG2 C4orf37 Homo sapiens (Human) 0.86898 0.067038 RDQQQNYCSFIPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.024 0 0 0 0 0 0 0 0 Q8N413 S2545_HUMAN Solute carrier family 25 member 45 SLC25A45 Homo sapiens (Human) mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] transmembrane transporter activity [GO:0022857] 0.89033 -0.47741 GLFRGAWALTLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.58665 0 Q8N414 PGBD5_HUMAN PiggyBac transposable element-derived protein 5 (EC 3.1.-.-) (PiggyBac domain-related protein 5) (PiggyBac transposase 5) PGBD5 Homo sapiens (Human) non-replicative DNA transposition [GO:0098038] nucleoplasm [GO:0005654]; nucleus [GO:0005634] endonuclease activity [GO:0004519]; transposase activity [GO:0004803] 0.83603 0.19018 APALLEAAR 0 0 0 0 0 0 0 0 0 9.38433 9.61556 9.54324 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N427 TXND3_HUMAN Thioredoxin domain-containing protein 3 (NM23-H8) (NME/NM23 family member 8) (Spermatid-specific thioredoxin-2) (Sptrx-2) NME8 SPTRX2 TXNDC3 Homo sapiens (Human) cell differentiation [GO:0030154]; cellular response to reactive oxygen species [GO:0034614]; cilium assembly [GO:0060271]; flagellated sperm motility [GO:0030317]; spermatogenesis [GO:0007283] axoneme [GO:0005930]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; outer dynein arm [GO:0036157]; sperm cytoplasmic droplet [GO:0097598]; sperm midpiece [GO:0097225]; sperm principal piece [GO:0097228] microtubule binding [GO:0008017] 0.82268 0.21538 LLSPDSIR 0 0 0 0 0 0 0 0 0 0 0 8.52282 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N431 RGF1C_HUMAN Ras-GEF domain-containing family member 1C RASGEF1C Homo sapiens (Human) positive regulation of GTPase activity [GO:0043547]; Ras protein signal transduction [GO:0007265] plasma membrane [GO:0005886] guanyl-nucleotide exchange factor activity [GO:0005085] 0.91528 -0.80483 DIYFLNEGCANR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.685 0 0 Q8N434 SVOPL_HUMAN Putative transporter SVOPL (SV2-related protein-like) (SVOP-like protein) SVOPL Homo sapiens (Human) membrane [GO:0016020] transmembrane transporter activity [GO:0022857] 0.95047 -1.4024 GRFADLLDAK 10.7708 10.6669 0 0 0 0 8.82915 0 9.24182 0 8.55317 8.68724 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N436 CPXM2_HUMAN Inactive carboxypeptidase-like protein X2 CPXM2 CPX2 UNQ676/PRO1310 Homo sapiens (Human) peptide metabolic process [GO:0006518]; protein processing [GO:0016485] extracellular space [GO:0005615] metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270] 0.95539 -1.538 EIMEKFGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0837 0 0 Q8N443 RIBC1_HUMAN RIB43A-like with coiled-coils protein 1 RIBC1 Homo sapiens (Human) 0.9554 -1.5607 VQEFREQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7597 0 0 Q8N446 ZN843_HUMAN Zinc finger protein 843 ZNF843 Homo sapiens (Human) metal ion binding [GO:0046872] 0.95423 -1.5322 GFTQSASLLQHWRVHSDWR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.81788 Q8N448 LNX2_HUMAN Ligand of Numb protein X 2 (Numb-binding protein 2) (PDZ domain-containing RING finger protein 1) LNX2 PDZRN1 Homo sapiens (Human) neural precursor cell proliferation [GO:0061351]; neuron differentiation [GO:0030182] plasma membrane [GO:0005886] identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165]; ubiquitin-protein transferase activity [GO:0004842] 0.9702 -3.2877 EEIFQVALHKR 0 0 0 0 0 0 9.36107 0 0 9.17515 12.0091 0 0 0 0 0 0 0 0 0 9.19473 0 0 0 0 0 0 Q8N456 LRC18_HUMAN Leucine-rich repeat-containing protein 18 LRRC18 UNQ9338/PRO34010 Homo sapiens (Human) cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231] 0.94352 -1.3339 LENLYVVEEK 8.74335 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N468 MFD4A_HUMAN Major facilitator superfamily domain-containing protein 4A (Major facilitator superfamily domain-containing protein 4) MFSD4A MFSD4 UNQ3064/PRO9894 Homo sapiens (Human) membrane [GO:0016020] glucose transmembrane transporter activity [GO:0005355] 0.81205 0.22355 SIGMENSECYQR 0 0 0 0 0 0 0 0 0 0 0 11.4533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N475 FSTL5_HUMAN Follistatin-related protein 5 (Follistatin-like protein 5) FSTL5 KIAA1263 Homo sapiens (Human) cell differentiation [GO:0030154]; regulation of BMP signaling pathway [GO:0030510] extracellular region [GO:0005576] calcium ion binding [GO:0005509] 0.91446 -0.82002 EGGYGLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5504 0 0 0 0 9.08592 0 0 0 0 0 0 Q8N4A0 GALT4_HUMAN Polypeptide N-acetylgalactosaminyltransferase 4 (EC 2.4.1.41) (Polypeptide GalNAc transferase 4) (GalNAc-T4) (pp-GaNTase 4) (Protein-UDP acetylgalactosaminyltransferase 4) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4) GALNT4 Homo sapiens (Human) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via serine [GO:0018242]; protein O-linked glycosylation via threonine [GO:0018243] extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; perinuclear region of cytoplasm [GO:0048471] carbohydrate binding [GO:0030246]; manganese ion binding [GO:0030145]; polypeptide N-acetylgalactosaminyltransferase activity [GO:0004653] 0.91334 -0.75437 LSDLQKNTEDLSRPLYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0266 0 0 0 0 0 0 0 0 0 0 0 0 Q8N4B4 FBX39_HUMAN F-box only protein 39 FBXO39 FBX39 Homo sapiens (Human) SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] SCF ubiquitin ligase complex [GO:0019005] 0.89954 -0.68465 ILKSQKER 12.1502 12.5279 12.257 0 0 0 0 11.1818 10.2488 12.1861 11.5653 11.5308 0 0 0 0 9.71235 9.47498 0 0 0 0 0 0 10.1777 0 0 Q8N4C6 NIN_HUMAN Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein) NIN KIAA1565 Homo sapiens (Human) centriole-centriole cohesion [GO:0010457]; centrosome localization [GO:0051642]; centrosome-templated microtubule nucleation [GO:0090222]; collateral sprouting [GO:0048668]; corpus callosum morphogenesis [GO:0021540]; corticospinal tract morphogenesis [GO:0021957]; microtubule anchoring at centrosome [GO:0034454]; positive regulation of axonogenesis [GO:0050772]; protein localization [GO:0008104] apical part of cell [GO:0045177]; axonal growth cone [GO:0044295]; centriolar subdistal appendage [GO:0120103]; centriole [GO:0005814]; centrosome [GO:0005813]; ciliary transition fiber [GO:0097539]; cytoplasmic microtubule [GO:0005881]; dendrite [GO:0030425]; mitotic spindle [GO:0072686]; mitotic spindle pole [GO:0097431]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; pericentriolar material [GO:0000242]; plasma membrane [GO:0005886]; spindle pole [GO:0000922] calcium ion binding [GO:0005509]; GTP binding [GO:0005525]; kinase binding [GO:0019900]; microtubule minus-end binding [GO:0051011] 0.96948 -5.6362 AELTHSREKVR 0 0 0 0 0 0 0 0 0 0 0 9.89695 0 0 0 10.5809 0 12.9137 0 9.77375 0 0 0 9.59119 0 10.6388 0 Q8N4C7 STX19_HUMAN Syntaxin-19 STX19 Homo sapiens (Human) exocytosis [GO:0006887]; intracellular protein transport [GO:0006886]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; vesicle docking [GO:0048278] endomembrane system [GO:0012505]; plasma membrane [GO:0005886]; presynaptic active zone membrane [GO:0048787]; SNARE complex [GO:0031201]; synaptic vesicle [GO:0008021] SNAP receptor activity [GO:0005484]; SNARE binding [GO:0000149] 0.92267 -0.94126 EMSEEDVNDMLHQGK 0 0 0 0 9.17465 0 0 0 0 12.0087 0 0 0 0 0 0 9.65462 0 0 0 0 0 0 0 0 0 0 Q8N4C8 MINK1_HUMAN Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6) MINK1 B55 MAP4K6 MINK YSK2 ZC3 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; brain development [GO:0007420]; chemical synaptic transmission [GO:0007268]; dendrite morphogenesis [GO:0048813]; JNK cascade [GO:0007254]; MAPK cascade [GO:0000165]; neuron projection morphogenesis [GO:0048812]; positive regulation of JNK cascade [GO:0046330]; positive regulation of p38MAPK cascade [GO:1900745]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of AMPA receptor activity [GO:2000311]; regulation of cell migration [GO:0030334]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell-matrix adhesion [GO:0001952]; regulation of MAPK cascade [GO:0043408] axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; postsynaptic density [GO:0014069] ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96585 -2.3606 EQEYKRK 0 0 0 9.29556 0 0 0 0 0 0 10.2431 0 0 0 0 0 0 0 0 9.29515 0 0 9.93842 10.0643 0 0 0 Q8N4E4 PDCL2_HUMAN Phosducin-like protein 2 PDCL2 Homo sapiens (Human) protein folding [GO:0006457] cytoplasm [GO:0005737] 0.87367 0.031645 DMVDMMVSSIR 0 8.51491 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N4F7 RN175_HUMAN RING finger protein 175 RNF175 Homo sapiens (Human) ubiquitin-dependent ERAD pathway [GO:0030433] endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630] 0.94083 -1.3279 ATRKPLSGRTPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.12967 Q8N4H5 TOM5_HUMAN Mitochondrial import receptor subunit TOM5 homolog TOMM5 C9orf105 TOM5 Homo sapiens (Human) protein insertion into mitochondrial outer membrane [GO:0045040]; protein targeting to mitochondrion [GO:0006626] mitochondrial outer membrane [GO:0005741]; mitochondrial outer membrane translocase complex [GO:0005742]; mitochondrion [GO:0005739] 0.92172 -1.1267 LDPEEMKRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4223 0 0 0 0 0 Q8N4L1 T151A_HUMAN Transmembrane protein 151A TMEM151A TMEM151 Homo sapiens (Human) membrane [GO:0016020] 0.84098 0.18368 ATPGVFR 0 0 0 0 0 0 0 9.57922 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N4L8 CCD24_HUMAN Coiled-coil domain-containing protein 24 CCDC24 Homo sapiens (Human) blastocyst hatching [GO:0001835] 0.96199 -2.5603 GQSATHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.89521 Q8N4N3 KLH36_HUMAN Kelch-like protein 36 KLHL36 C16orf44 Homo sapiens (Human) protein ubiquitination [GO:0016567] cullin family protein binding [GO:0097602] 0.56188 0.50732 VAPLLHANSESGVAVWEGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.95524 0 0 Q8N4P2 IT70B_HUMAN Intraflagellar transport protein 70B (Tetratricopeptide repeat protein 30B) (TPR repeat protein 30B) IFT70B TTC30B Homo sapiens (Human) cilium assembly [GO:0060271]; intraciliary anterograde transport [GO:0035720]; intraciliary transport [GO:0042073] axonemal microtubule [GO:0005879]; ciliary tip [GO:0097542]; cilium [GO:0005929]; intraciliary transport particle B [GO:0030992] intraciliary transport particle B binding [GO:0120170] 0.88478 -0.24507 EEEQLSYDDPDK 0 0 0 0 0 0 0 0 0 10.5736 0 0 0 0 0 0 0 0 0 0 10.4613 0 0 0 9.58502 0 0 Q8N4Q0 PTGR3_HUMAN Prostaglandin reductase 3 (PRG-3) (EC 1.3.1.48) (Zinc-binding alcohol dehydrogenase domain-containing protein 2) PTGR3 ZADH2 Homo sapiens (Human) negative regulation of fat cell differentiation [GO:0045599] peroxisome [GO:0005777] 13-prostaglandin reductase activity [GO:0036132]; 15-oxoprostaglandin 13-oxidase activity [GO:0047522]; zinc ion binding [GO:0008270] 0.87367 0.025248 AVNYMYMGK 0 9.74557 0 0 0 0 0 0 0 9.28533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N4S0 CCD82_HUMAN Coiled-coil domain-containing protein 82 CCDC82 HT025 Homo sapiens (Human) nucleus [GO:0005634] 0.69623 0.38022 NIDLQDQEK 0 0 0 0 0 0 0 0 0 0 9.34607 0 0 0 0 9.25894 0 0 0 0 0 0 0 0 0 0 0 Q8N4S9 MALD2_HUMAN MARVEL domain-containing protein 2 (Tricellulin) MARVELD2 TRIC Homo sapiens (Human) bicellular tight junction assembly [GO:0070830]; cell-cell junction organization [GO:0045216]; establishment of endothelial barrier [GO:0061028]; sensory perception of sound [GO:0007605] apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; paranodal junction [GO:0033010]; Schmidt-Lanterman incisure [GO:0043220]; tight junction [GO:0070160]; tricellular tight junction [GO:0061689] 0.96914 -3.0291 ISRIHEEFK 0 9.74619 0 0 8.49753 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4385 0 0 9.40911 0 0 0 0 Q8N4U5 T11L2_HUMAN T-complex protein 11-like protein 2 TCP11L2 Homo sapiens (Human) signal transduction [GO:0007165] 0.93998 -1.3002 LTRISAVLLEGMNKETFNLK 0 9.2658 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N4V2 SVOP_HUMAN Synaptic vesicle 2-related protein (SV2-related protein) SVOP Homo sapiens (Human) basal plasma membrane [GO:0009925]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672] transmembrane transporter activity [GO:0022857] 0.91907 -0.89958 GLQESSHR 0 0 0 0 13.0389 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.82197 Q8N4W9 ZN808_HUMAN Zinc finger protein 808 ZNF808 Homo sapiens (Human) nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.9147 -0.80351 AFVRNSYLARHIR 9.05156 0 8.92914 9.25538 9.29235 9.48077 0 9.41638 12.7359 0 10.5121 0 0 9.25564 0 0 0 0 0 0 9.5724 0 9.03829 0 0 10.1163 0 Q8N4X5 AF1L2_HUMAN Actin filament-associated protein 1-like 2 (AFAP1-like protein 2) AFAP1L2 KIAA1914 XB130 Homo sapiens (Human) inflammatory response [GO:0006954]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of interleukin-8 production [GO:0032757]; regulation of interleukin-6 production [GO:0032675]; regulation of mitotic cell cycle [GO:0007346] cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886] protein tyrosine kinase activator activity [GO:0030296]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124] 0.96943 -5.5258 ICAFLWRKK 0 0 0 0 0 0 0 0 0 0 8.84467 0 0 0 0 0 0 0 0 9.07711 0 0 0 0 10.1762 0 0 Q8N4Y2 EFC4A_HUMAN EF-hand calcium-binding domain-containing protein 4A (Calcium release-activated calcium channel regulator 2B) (CRAC channel regulator 2B) (Calcium release-activated channel regulator 2B) CRACR2B EFCAB4A Homo sapiens (Human) regulation of store-operated calcium entry [GO:2001256]; store-operated calcium entry [GO:0002115] cytoplasm [GO:0005737] calcium ion binding [GO:0005509] 0.9683 -3.6171 ALYEETEQLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0863 0 11.0201 0 0 0 0 0 0 10.0402 0 0 Q8N511 TM199_HUMAN Transmembrane protein 199 TMEM199 C17orf32 Homo sapiens (Human) cellular response to increased oxygen levels [GO:0036295]; intracellular iron ion homeostasis [GO:0006879]; lysosomal lumen acidification [GO:0007042]; lysosomal protein catabolic process [GO:1905146]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072] COPI-coated vesicle membrane [GO:0030663]; endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; lysosome [GO:0005764]; vacuolar proton-transporting V-type ATPase complex [GO:0016471] 0.32947 0.78113 DLHQHLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.11964 0 0 0 0 0 0 8.96973 9.46526 9.40644 0 0 0 Q8N531 FBXL6_HUMAN F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6) (FBL6A) FBXL6 FBL6 Homo sapiens (Human) proteolysis [GO:0006508]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] SCF ubiquitin ligase complex [GO:0019005] ubiquitin-protein transferase activity [GO:0004842] 0.95189 -1.4526 LLDLRGCAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.258 0 0 0 0 0 0 Q8N543 OGFD1_HUMAN Prolyl 3-hydroxylase OGFOD1 (EC 1.14.11.-) (2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1) (Termination and polyadenylation 1 homolog) (uS12 prolyl 3-hydroxylase) OGFOD1 KIAA1612 TPA1 Homo sapiens (Human) cell population proliferation [GO:0008283]; peptidyl-proline hydroxylation [GO:0019511]; protein hydroxylation [GO:0018126]; regulation of translational termination [GO:0006449]; stress granule assembly [GO:0034063] cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654] iron ion binding [GO:0005506]; L-ascorbic acid binding [GO:0031418]; peptidyl-proline 3-dioxygenase activity [GO:0031544]; peptidyl-proline dioxygenase activity [GO:0031543] 0.84487 0.13433 ELMNLDFHEK 0 0 0 0 0 0 0 0 0 0 9.48361 9.31036 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N554 ZN276_HUMAN Zinc finger protein 276 (Zfp-276) (Zinc finger protein 477) ZNF276 CENP-Z ZFP276 ZNF477 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] chromosome [GO:0005694]; kinetochore [GO:0000776]; nucleus [GO:0005634] chromatin insulator sequence binding [GO:0043035]; sequence-specific double-stranded DNA binding [GO:1990837]; zinc ion binding [GO:0008270] 0.86975 0.057946 GADGMKK 0 0 9.24812 0 0 0 0 9.11788 0 8.68292 9.31569 0 8.60199 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N568 DCLK2_HUMAN Serine/threonine-protein kinase DCLK2 (EC 2.7.11.1) (CaMK-like CREB regulatory kinase 2) (CL2) (CLICK-II) (CLICK2) (Doublecortin domain-containing protein 3B) (Doublecortin-like and CAM kinase-like 2) (Doublecortin-like kinase 2) DCLK2 DCAMKL2 DCDC3B DCK2 Homo sapiens (Human) hippocampus development [GO:0021766]; intracellular signal transduction [GO:0035556]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of protein localization to nucleus [GO:1900181]; peptidyl-serine phosphorylation [GO:0018105]; protein localization to nucleus [GO:0034504]; pyramidal neuron development [GO:0021860] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856] ATP binding [GO:0005524]; microtubule binding [GO:0008017]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96992 -3.2709 ELISQMLQVNVEAR 0 0 0 0 0 0 0 0 0 0 0 10.8829 0 0 0 0 0 0 0 0 0 0 0 8.35156 0 0 0 Q8N584 TT39C_HUMAN Tetratricopeptide repeat protein 39C (TPR repeat protein 39C) TTC39C C18orf17 Homo sapiens (Human) cilium assembly [GO:0060271]; otolith morphogenesis [GO:0032474] 0.88189 -0.11585 EAAYPNSSLFMFFK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3383 0 0 0 0 0 0 0 0 0 0 0 0 9.02633 Q8N587 ZN561_HUMAN Zinc finger protein 561 ZNF561 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.91783 -0.87249 ECGKAFAVSSRLSR 0 0 0 0 0 0 0 0 8.5783 0 0 0 0 0 0 0 0 0 0 0 10.1118 0 0 0 0 0 0 Q8N594 MPND_HUMAN MPN domain-containing protein (EC 3.4.-.-) MPND Homo sapiens (Human) double-strand break repair [GO:0006302]; histone H2A K63-linked deubiquitination [GO:0070537] BRCA1-A complex [GO:0070531]; BRISC complex [GO:0070552] metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; polyubiquitin modification-dependent protein binding [GO:0031593] 0.88543 -0.33322 ISLASRTPK 0 0 0 0 0 0 0 0 0 0 0 9.43806 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N5A5 ZGPAT_HUMAN Zinc finger CCCH-type with G patch domain-containing protein (G patch domain-containing protein 6) (Zinc finger CCCH domain-containing protein 9) (Zinc finger and G patch domain-containing protein) ZGPAT GPATC6 GPATCH6 KIAA1847 ZC3H9 ZC3HDC9 ZIP Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]" 0.92189 -1.0986 GKSLDQCVETLQK 0 0 0 0 0 9.59348 0 9.34027 0 9.76688 9.75322 0 0 0 0 0 0 0 0 0 0 0 0 0 9.24572 0 0 Q8N5B7 CERS5_HUMAN Ceramide synthase 5 (CerS5) (LAG1 longevity assurance homolog 5) (Sphingoid base N-palmitoyltransferase CERS5) (EC 2.3.1.291) (Sphingosine N-acyltransferase CERS5) (EC 2.3.1.24) CERS5 LASS5 Homo sapiens (Human) ceramide biosynthetic process [GO:0046513]; sphingolipid biosynthetic process [GO:0030148] endoplasmic reticulum membrane [GO:0005789] DNA binding [GO:0003677]; sphingosine N-acyltransferase activity [GO:0050291] 0.95421 -1.5146 IQCWFRHR 0 10.1586 10.1992 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N5C6 SRBD1_HUMAN S1 RNA-binding domain-containing protein 1 SRBD1 Homo sapiens (Human) nucleobase-containing compound metabolic process [GO:0006139]; translation [GO:0006412] mRNA binding [GO:0003729]; structural constituent of ribosome [GO:0003735] 0.89893 -0.66166 HVCIQSSLAK 0 0 0 0 0 0 9.42335 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N5C8 TAB3_HUMAN TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 3) (NF-kappa-B-activating protein 1) (TAK1-binding protein 3) (TAB-3) (TGF-beta-activated kinase 1-binding protein 3) TAB3 MAP3K7IP3 Homo sapiens (Human) negative regulation of autophagy [GO:0010507]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] K63-linked polyubiquitin modification-dependent protein binding [GO:0070530]; molecular adaptor activity [GO:0060090]; ubiquitin binding [GO:0043130]; zinc ion binding [GO:0008270] 0.95435 -1.5159 TGSTQSPRTQPR 0 0 0 0 0 0 10.4867 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N5F7 NKAP_HUMAN NF-kappa-B-activating protein NKAP Homo sapiens (Human) granulocyte differentiation [GO:0030851]; hematopoietic stem cell proliferation [GO:0071425]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; somatic stem cell population maintenance [GO:0035019]; T cell differentiation in thymus [GO:0033077] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; RNA binding [GO:0003723] 0.96479 -2.2838 NQSYRSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.6311 0 0 0 Q8N5H3 LRA25_HUMAN Leucine repeat adapter protein 25 FAM89B Lrap25 Homo sapiens (Human) establishment of cell polarity [GO:0030010]; negative regulation of SMAD protein signal transduction [GO:0060392]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of cell migration [GO:0030335] cytoplasm [GO:0005737]; lamellipodium [GO:0030027] transcription corepressor binding [GO:0001222] 0.95384 -1.5167 ELERVYSQR 0 0 0 0 0 0 0 0 0 0 0 0 10.3667 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N5I3 KCNRG_HUMAN Potassium channel regulatory protein (Potassium channel regulator) (Protein CLLD4) KCNRG CLLD4 Homo sapiens (Human) negative regulation of delayed rectifier potassium channel activity [GO:1902260]; protein homooligomerization [GO:0051260] endoplasmic reticulum [GO:0005783] identical protein binding [GO:0042802] 0.95089 -1.4004 EALFYELR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.9639 0 0 0 0 0 0 0 0 0 0 0 0 Q8N5K1 CISD2_HUMAN CDGSH iron-sulfur domain-containing protein 2 (Endoplasmic reticulum intermembrane small protein) (MitoNEET-related 1 protein) (Miner1) (Nutrient-deprivation autophagy factor-1) (NAF-1) CISD2 CDGSH2 ERIS ZCD2 Homo sapiens (Human) autophagy of mitochondrion [GO:0000422]; regulation of autophagy [GO:0010506] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; perinuclear endoplasmic reticulum [GO:0097038]; protein-containing complex [GO:0032991] "2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]" 0.076023 1.2494 LPVPESITGFAR 0 0 0 0 0 0 8.57531 8.66562 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N5N7 RM50_HUMAN "Large ribosomal subunit protein mL50 (39S ribosomal protein L50, mitochondrial) (L50mt) (MRP-L50)" MRPL50 Homo sapiens (Human) mitochondrial translation [GO:0032543] cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial large ribosomal subunit [GO:0005762]; mitochondrion [GO:0005739] 0.9236 -1.0468 EFWSRFRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.50226 0 0 0 0 0 0 0 0 Q8N5P1 ZC3H8_HUMAN Zinc finger CCCH domain-containing protein 8 ZC3H8 ZC3HDC8 Homo sapiens (Human) apoptotic process [GO:0006915]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of T cell differentiation in thymus [GO:0033085]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase III [GO:0045945]; response to antibiotic [GO:0046677]; snRNA transcription by RNA polymerase II [GO:0042795]; snRNA transcription by RNA polymerase III [GO:0042796]; T cell homeostasis [GO:0043029] Cajal body [GO:0015030]; chromatin [GO:0000785]; euchromatin [GO:0000791]; histone locus body [GO:0035363]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription elongation factor complex [GO:0008023] "DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding [GO:0001162]" 0.95465 -1.5753 IKLECEQIPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.1703 0 0 0 0 0 0 0 0 0 10.3905 0 0 Q8N5R6 CCD33_HUMAN Coiled-coil domain-containing protein 33 (Cancer/testis antigen 61) (CT61) CCDC33 Homo sapiens (Human) peroxisome [GO:0005777] 0.63804 0.39718 ADEATAK 8.74514 8.7733 0 0 0 0 0 0 8.33954 9.11723 9.00374 8.21985 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N5S1 S2541_HUMAN Mitochondrial carrier protein SCaMC-3L (Mitochondrial ATP-Mg/Pi carrier protein SLC25A41) (Small calcium-binding mitochondrial carrier protein 3-like) (SCaMC-3-like) (SCaMC-3L) (Solute carrier family 25 member 41) SLC25A41 Homo sapiens (Human) ADP transport [GO:0015866]; ATP transport [GO:0015867]; mitochondrial ADP transmembrane transport [GO:0140021]; mitochondrial ATP transmembrane transport [GO:1990544] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] ADP transmembrane transporter activity [GO:0015217]; ATP transmembrane transporter activity [GO:0005347] 0.92962 -1.2456 QILQREGTR 0 0 0 0 0 0 0 0 0 0 0 10.202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N5S9 KKCC1_HUMAN Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) (CaMKK 1) (EC 2.7.11.17) (CaM-kinase IV kinase) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-KK alpha) (CaM-kinase kinase alpha) (CaMKK alpha) CAMKK1 CAMKKA Homo sapiens (Human) intracellular signal transduction [GO:0035556]; positive regulation of protein kinase activity [GO:0045860]; protein phosphorylation [GO:0006468] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654] ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; protein serine kinase activity [GO:0106310] 0.84713 0.15401 IGVPDIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.41937 0 0 0 0 0 0 0 0 0 0 0 Q8N5U0 CK042_HUMAN Uncharacterized protein C11orf42 C11orf42 Homo sapiens (Human) 0.86964 0.044123 SLPVAFSCLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0408 0 0 0 0 0 0 0 Q8N5U6 RNF10_HUMAN E3 ubiquitin-protein ligase RNF10 (EC 2.3.2.27) (RING finger protein 10) RNF10 KIAA0262 RIE2 Homo sapiens (Human) negative regulation of Schwann cell proliferation [GO:0010626]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of myelination [GO:0031643]; positive regulation of transcription by RNA polymerase II [GO:0045944]; postsynapse to nucleus signaling pathway [GO:0099527]; protein autoubiquitination [GO:0051865]; protein monoubiquitination [GO:0006513]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] cytoplasm [GO:0005737]; extrinsic component of postsynaptic density membrane [GO:0099147]; glutamatergic synapse [GO:0098978]; nucleus [GO:0005634] metal ion binding [GO:0046872]; transcription cis-regulatory region binding [GO:0000976]; ubiquitin protein ligase activity [GO:0061630] 0.96766 -2.8159 CLVREYGSLER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0151 0 0 0 0 0 Q8N5V2 NGEF_HUMAN Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor) NGEF Homo sapiens (Human) activation of GTPase activity [GO:0090630]; cell differentiation [GO:0030154]; ephrin receptor signaling pathway [GO:0048013]; negative regulation of dendritic spine morphogenesis [GO:0061002]; nervous system development [GO:0007399]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056] cytosol [GO:0005829]; growth cone [GO:0030426]; membrane [GO:0016020] guanyl-nucleotide exchange factor activity [GO:0005085] 0.87188 0.028529 TLPQICLLSNPHSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5111 0 0 0 0 0 0 Q8N5X7 IF4E3_HUMAN Eukaryotic translation initiation factor 4E type 3 (eIF-4E type 3) (eIF-4E3) (eIF4E type 3) (eIF4E-3) EIF4E3 Homo sapiens (Human) cytosol [GO:0005829]; eukaryotic translation initiation factor 4F complex [GO:0016281]; mRNA cap binding complex [GO:0005845] RNA 7-methylguanosine cap binding [GO:0000340]; translation initiation factor activity [GO:0003743] 0.42382 0.66655 SLPGATAAECASNLKK 9.32136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N5Y2 MS3L1_HUMAN Male-specific lethal 3 homolog (Male-specific lethal-3 homolog 1) (Male-specific lethal-3 protein-like 1) (MSL3-like 1) MSL3 MSL3L1 Homo sapiens (Human) histone deacetylation [GO:0016575]; histone H2A acetylation [GO:0043968]; histone H4-K16 acetylation [GO:0043984]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription [GO:0006355]; regulation of dosage compensation by inactivation of X chromosome [GO:1900095] MSL complex [GO:0072487]; NuA4 histone acetyltransferase complex [GO:0035267]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; histone H4K16 acetyltransferase activity [GO:0046972]; methylated histone binding [GO:0035064] 0.87023 0.056267 EMVDGLR 0 0 0 0 0 0 0 0 0 0 10.0729 0 0 0 9.26137 0 0 0 0 0 0 0 0 0 0 0 0 Q8N5Y8 PAR16_HUMAN Protein mono-ADP-ribosyltransferase PARP16 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 15) (Poly [ADP-ribose] polymerase 16) (PARP-16) PARP16 ARTD15 C15orf30 Homo sapiens (Human) cellular response to leukemia inhibitory factor [GO:1990830]; endoplasmic reticulum unfolded protein response [GO:0030968]; IRE1-mediated unfolded protein response [GO:0036498]; NAD biosynthesis via nicotinamide riboside salvage pathway [GO:0034356]; negative regulation of cytoplasmic translation [GO:2000766]; protein auto-ADP-ribosylation [GO:0070213]; viral protein processing [GO:0019082] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum tubular network [GO:0071782]; membrane [GO:0016020]; nuclear envelope [GO:0005635] kinase binding [GO:0019900]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+- protein-aspartate ADP-ribosyltransferase activity [GO:0140806]; NAD+- protein-lysine ADP-ribosyltransferase activity [GO:0140804]; NAD+-protein ADP-ribosyltransferase activity [GO:1990404]; NAD+-protein-glutamate ADP-ribosyltransferase activity [GO:0140807]; nucleotidyltransferase activity [GO:0016779]; protein serine/threonine kinase activator activity [GO:0043539]; translation regulator activity [GO:0045182] 0.93989 -1.303 QPSGWAAAREAAGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0013 0 0 0 Q8N5Z0 AADAT_HUMAN "Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial (KAT/AadAT) (2-aminoadipate aminotransferase) (2-aminoadipate transaminase) (EC 2.6.1.39) (Alpha-aminoadipate aminotransferase) (AadAT) (Glycine transaminase AADAT) (EC 2.6.1.4) (Kynurenine aminotransferase II) (Kynurenine--glyoxylate transaminase AADAT) (EC 2.6.1.63) (Kynurenine--oxoglutarate aminotransferase II) (Kynurenine--oxoglutarate transaminase 2) (EC 2.6.1.7) (Kynurenine--oxoglutarate transaminase II) (Methionine--glyoxylate transaminase AADAT) (EC 2.6.1.73)" AADAT KAT2 KYAT2 Homo sapiens (Human) 2-oxoglutarate metabolic process [GO:0006103]; alpha-amino acid metabolic process [GO:1901605]; biosynthetic process [GO:0009058]; glutamate metabolic process [GO:0006536]; kynurenine metabolic process [GO:0070189]; L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512] mitochondrial matrix [GO:0005759] 2-aminoadipate transaminase activity [GO:0047536]; glycine:2-oxoglutarate aminotransferase activity [GO:0047958]; kynurenine-glyoxylate transaminase activity [GO:0047315]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; methionine-glyoxylate transaminase activity [GO:0050094]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170] 0.80787 0.23033 TIQFGEEMMK 0 0 0 0 0 9.39594 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1621 0 0 0 Q8N5Z5 KCD17_HUMAN BTB/POZ domain-containing protein KCTD17 KCTD17 Homo sapiens (Human) cell projection organization [GO:0030030]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; positive regulation of cilium assembly [GO:0045724]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein homooligomerization [GO:0051260] Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783] cullin family protein binding [GO:0097602]; identical protein binding [GO:0042802] 0.63221 0.39792 AAGGWGK 0 0 0 8.46495 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.54361 0 Q8N616 TM148_HUMAN Putative uncharacterized protein encoded by LINC00311 LINC00311 NCRNA00311 TMEM148 Homo sapiens (Human) 0.87757 -0.0047299 TLFWSEWAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2293 0 0 0 0 0 Q8N635 MEIOB_HUMAN Meiosis-specific with OB domain-containing protein (EC 3.1.-.-) MEIOB C16orf73 Homo sapiens (Human) double-strand break repair via homologous recombination [GO:0000724]; female meiosis I [GO:0007144]; fertilization [GO:0009566]; homologous chromosome pairing at meiosis [GO:0007129]; male meiotic nuclear division [GO:0007140]; resolution of meiotic recombination intermediates [GO:0000712] chromosome [GO:0005694]; cytoplasm [GO:0005737]; nucleus [GO:0005634] chromatin binding [GO:0003682]; single-stranded DNA 3'-5' DNA exonuclease activity [GO:0008310]; single-stranded DNA binding [GO:0003697] 0.93316 -1.2843 TDVKGFPDRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.95492 0 0 0 0 0 0 0 0 0 0 0 Q8N684 CPSF7_HUMAN Cleavage and polyadenylation specificity factor subunit 7 (Cleavage and polyadenylation specificity factor 59 kDa subunit) (CPSF 59 kDa subunit) (Cleavage factor Im complex 59 kDa subunit) (CFIm59) (Pre-mRNA cleavage factor Im 59 kDa subunit) CPSF7 Homo sapiens (Human) messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA 3'-end processing [GO:0031124]; mRNA alternative polyadenylation [GO:0110104]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262] cytoplasm [GO:0005737]; membrane [GO:0016020]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] mRNA binding [GO:0003729]; RNA binding [GO:0003723] 0.92435 -0.99443 QNLSQFEAQAR 0 10.908 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.305 10.6372 0 0 Q8N687 DB125_HUMAN "Beta-defensin 125 (Beta-defensin 25) (DEFB-25) (Defensin, beta 125)" DEFB125 DEFB25 Homo sapiens (Human) defense response to bacterium [GO:0042742]; innate immune response [GO:0045087] extracellular region [GO:0005576] 0.91601 -0.84074 RCLDTER 0 0 0 0 0 0 0 0 0 8.79756 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N693 ESX1_HUMAN "Homeobox protein ESX1 (Extraembryonic, spermatogenesis, homeobox 1) [Cleaved into: Homeobox protein ESX1-N; Homeobox protein ESX1-C]" ESX1 ESX1L ESX1R Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of cell cycle [GO:0051726]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.95437 -1.5014 LAARLNLTEDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.76439 0 0 0 0 0 0 0 0 0 0 Q8N6C5 IGSF1_HUMAN Immunoglobulin superfamily member 1 (IgSF1) (Immunoglobulin-like domain-containing protein 1) (Inhibin-binding protein) (InhBP) (Pituitary gland-specific factor 2) (p120) IGSF1 IGDC1 KIAA0364 PGSF2 Homo sapiens (Human) negative regulation of activin receptor signaling pathway [GO:0032926]; regulation of DNA-templated transcription [GO:0006355] extracellular region [GO:0005576]; membrane [GO:0016020] activin receptor antagonist activity [GO:0038102]; coreceptor activity [GO:0015026]; inhibin binding [GO:0034711] 0.95457 -1.5195 LGKAITLQCR 0 0 0 0 0 0 0 0 9.62523 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N6C7 PGSF1_HUMAN Putative uncharacterized protein encoded by MIR7-3HG (Pituitary gland-specific factor 1) MIR7-3HG C19orf30 LINC00306 NCRNA00306 PGSF1 Homo sapiens (Human) 0.96407 -2.2551 AETSRADCLGAPNIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.77232 0 0 0 0 0 0 0 0 0 0 Q8N6C8 LIRA3_HUMAN Leukocyte immunoglobulin-like receptor subfamily A member 3 (CD85 antigen-like family member E) (Immunoglobulin-like transcript 6) (ILT-6) (Leukocyte immunoglobulin-like receptor 4) (LIR-4) (Monocyte inhibitory receptor HM43/HM31) (CD antigen CD85e) LILRA3 ILT6 LIR4 Homo sapiens (Human) adaptive immune response [GO:0002250]; cytokine-mediated signaling pathway [GO:0019221] extracellular region [GO:0005576]; ficolin-1-rich granule membrane [GO:0101003]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821] inhibitory MHC class I receptor activity [GO:0032396] 0.90548 -0.72858 WSYRCYGYDSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.62954 0 0 0 0 0 0 0 0 0 Q8N6G5 CGAT2_HUMAN "Chondroitin sulfate N-acetylgalactosaminyltransferase 2 (EC 2.4.1.174) (Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2) (Beta4GalNAcT-2) (GalNAcT-2)" CSGALNACT2 CHGN2 GALNACT2 PRO0082 Homo sapiens (Human) "chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate proteoglycan biosynthetic process [GO:0050650]; chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0050653]; dermatan sulfate proteoglycan biosynthetic process [GO:0050651]; dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0050652]; proteoglycan biosynthetic process [GO:0030166]" Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; membrane [GO:0016020] acetylgalactosaminyltransferase activity [GO:0008376]; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity [GO:0047238]; glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity [GO:0047237]; metal ion binding [GO:0046872] 0.96357 -2.1197 IHLTVVYFGKEGLSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.41971 0 0 0 0 0 0 0 0 0 0 0 0 Q8N6I1 EID2_HUMAN EP300-interacting inhibitor of differentiation 2 (EID-2) (CREBBP/EP300 inhibitor 2) (EID-1-like inhibitor of differentiation 2) EID2 CRI2 Homo sapiens (Human) cell differentiation [GO:0030154]; muscle organ development [GO:0007517]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; regulation of cell population proliferation [GO:0042127]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; SMAD protein complex assembly [GO:0007183]; transforming growth factor beta receptor complex assembly [GO:0007181] nucleoplasm [GO:0005654]; nucleus [GO:0005634] SMAD binding [GO:0046332]; transcription corepressor activity [GO:0003714] 0.91526 -0.77043 IQELEERR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4871 0 0 Q8N6K7 SAMD3_HUMAN Sterile alpha motif domain-containing protein 3 (SAM domain-containing protein 3) SAMD3 Homo sapiens (Human) 0.96786 -2.8724 MVQQLVKK 0 0 0 0 0 0 0 11.3272 0 0 10.2748 0 0 0 0 0 0 0 0 0 0 0 0 9.57726 0 0 0 Q8N6L0 KASH5_HUMAN Protein KASH5 (Coiled-coil domain-containing protein 155) (KASH domain-containing protein 5) KASH5 CCDC155 Homo sapiens (Human) actin filament organization [GO:0007015]; chromosome localization to nuclear envelope involved in homologous chromosome segregation [GO:0090220]; double-strand break repair via homologous recombination [GO:0000724]; homologous chromosome pairing at meiosis [GO:0007129]; microtubule cytoskeleton organization involved in homologous chromosome segregation [GO:0090172]; oogenesis [GO:0048477]; spermatogenesis [GO:0007283]; spindle assembly [GO:0051225]; spindle localization [GO:0051653]; telomere localization [GO:0034397] "chromosome, telomeric region [GO:0000781]; lateral element [GO:0000800]; meiotic nuclear membrane microtubule tethering complex [GO:0034993]; meiotic spindle pole [GO:0090619]; nuclear outer membrane [GO:0005640]" dynein complex binding [GO:0070840]; identical protein binding [GO:0042802] 0.88205 -0.080874 ATVDLDTFLVVMR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16.7133 0 0 0 0 0 0 10.8474 0 0 Q8N6M5 ALLC_HUMAN Probable inactive allantoicase (Allantoate amidinohydrolase) ALLC Homo sapiens (Human) allantoin catabolic process [GO:0000256] allantoicase activity [GO:0004037] 0.87666 -0.00090335 EHEYTEFGK 0 0 0 0 0 9.4113 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N6M6 AMPO_HUMAN Aminopeptidase O (AP-O) (EC 3.4.11.-) AOPEP C9orf3 ONPEP Homo sapiens (Human) proteolysis [GO:0006508] cytosol [GO:0005829]; nucleolus [GO:0005730] metalloaminopeptidase activity [GO:0070006]; zinc ion binding [GO:0008270] 0.94724 -1.3488 ACLRWRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.008 0 0 0 0 0 0 0 0 Q8N6M8 IQCF1_HUMAN IQ domain-containing protein F1 IQCF1 Homo sapiens (Human) positive regulation of acrosome reaction [GO:2000344]; positive regulation of flagellated sperm motility involved in capacitation [GO:0060474] acrosomal vesicle [GO:0001669] calmodulin binding [GO:0005516] 0.92157 -1.0882 EWAAVTLQSQAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.716 Q8N6N3 CA052_HUMAN UPF0690 protein C1orf52 (BCL10-associated gene protein) C1orf52 BAG GM117 Homo sapiens (Human) nucleoplasm [GO:0005654] RNA binding [GO:0003723] 0.84261 0.15187 APEEPPK 0 0 0 0 9.54237 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N6N6 NATD1_HUMAN Protein NATD1 (N-acetyltransferase domain-containing protein 1) NATD1 C17orf103 GTLF3B Homo sapiens (Human) 0.9155 -0.77611 MAHSAAAVPLGALEQGCPIRVEHDR 0 0 10.1268 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N6P7 I22R1_HUMAN Interleukin-22 receptor subunit alpha-1 (IL-22 receptor subunit alpha-1) (IL-22R-alpha-1) (IL-22RA1) (Cytokine receptor class-II member 9) (Cytokine receptor family 2 member 9) (CRF2-9) (ZcytoR11) IL22RA1 IL22R Homo sapiens (Human) defense response to Gram-negative bacterium [GO:0050829]; negative regulation of inflammatory response [GO:0050728] plasma membrane [GO:0005886] interferon receptor activity [GO:0004904]; interleukin-20 binding [GO:0042015]; interleukin-22 receptor activity [GO:0042018] 0.90751 -0.73837 GLALTVQWES 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1803 0 0 0 0 Q8N6Q1 TMC5A_HUMAN Transmembrane and coiled-coil domain-containing protein 5A TMCO5A TMCO5 Homo sapiens (Human) membrane [GO:0016020] 0.85014 0.10869 IEEELEALFLER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.20814 0 Q8N6Q8 MET25_HUMAN Probable methyltransferase-like protein 25 (EC 2.1.1.-) METTL25 C12orf26 Homo sapiens (Human) methylation [GO:0032259] methyltransferase activity [GO:0008168] 0.94339 -1.3336 AVEFMNMKK 9.81884 0 0 0 0 0 9.60491 9.44867 9.50629 0 10.1227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N6S4 AN13C_HUMAN Ankyrin repeat domain-containing protein 13C ANKRD13C Homo sapiens (Human) protein retention in ER lumen [GO:0006621]; regulation of anoikis [GO:2000209]; regulation of signaling receptor activity [GO:0010469] cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; perinuclear region of cytoplasm [GO:0048471] signaling receptor binding [GO:0005102] 0.92029 -1.1426 GGKACHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.4302 0 0 0 0 0 0 0 0 0 0 0 0 Q8N6T0 TO6BL_HUMAN Type 2 DNA topoisomerase 6 subunit B-like (Type 2 DNA topoisomerase VI subunit B-like) (TOPOVIBL) TOP6BL C11orf80 Homo sapiens (Human) meiotic DNA double-strand break formation [GO:0042138]; reciprocal meiotic recombination [GO:0007131] chromosome [GO:0005694] 0.91616 -0.83713 QQLTLEKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.4108 Q8N6V9 TEX9_HUMAN Testis-expressed protein 9 TEX9 Homo sapiens (Human) centriolar satellite [GO:0034451]; cytoplasm [GO:0005737] 0.8417 0.17777 MHIEAAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.9086 0 0 0 0 0 0 0 0 0 0 Q8N6W0 CELF5_HUMAN CUGBP Elav-like family member 5 (CELF-5) (Bruno-like protein 5) (CUG-BP- and ETR-3-like factor 5) (RNA-binding protein BRUNOL-5) CELF5 BRUNOL5 Homo sapiens (Human) "mRNA splice site selection [GO:0006376]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]" cytoplasm [GO:0005737]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002] 0.21622 0.89934 LFVGMLNK 0 0 0 8.45146 8.47468 0 0 0 0 0 0 11.2994 10.0065 9.65637 9.79667 0 0 0 9.98883 0 0 9.91331 0 0 10.6932 10.7169 10.9106 Q8N6Y2 LRC17_HUMAN Leucine-rich repeat-containing protein 17 (p37NB) LRRC17 P37NB UNQ3076/PRO9909 Homo sapiens (Human) bone marrow development [GO:0048539]; negative regulation of osteoclast differentiation [GO:0045671]; ossification [GO:0001503] extracellular matrix [GO:0031012]; extracellular space [GO:0005615] 0.9164 -0.84751 LPAYPESFDQDTEDDEWEK 8.96423 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N715 CC185_HUMAN Coiled-coil domain-containing protein 185 CCDC185 C1orf65 Homo sapiens (Human) 0.95911 -1.8286 DSQRKNVPPGESR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5781 0 0 0 0 0 9.75891 0 0 0 Q8N766 EMC1_HUMAN ER membrane protein complex subunit 1 EMC1 KIAA0090 PSEC0263 Homo sapiens (Human) protein insertion into ER membrane by stop-transfer membrane-anchor sequence [GO:0045050]; tail-anchored membrane protein insertion into ER membrane [GO:0071816] EMC complex [GO:0072546]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; protein-containing complex [GO:0032991] 0.94732 -1.3548 FDWRQQYVGK 0 0 0 0 0 0 0 0 0 9.09703 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N782 ZN525_HUMAN Zinc finger protein 525 ZNF525 KIAA1979 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.80211 0.24048 LHSGEKPCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.74992 0 0 0 0 0 0 0 0 0 0 0 Q8N7A1 KLDC1_HUMAN Kelch domain-containing protein 1 KLHDC1 MSTP025 Homo sapiens (Human) protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] Cul5-RING ubiquitin ligase complex [GO:0031466]; cytoplasm [GO:0005737]; cytosol [GO:0005829] ubiquitin ligase-substrate adaptor activity [GO:1990756] 0.22157 0.87878 ITFWAAANHR 9.10515 8.82337 9.0562 0 0 0 0 0 0 0 0 0 8.39618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N7B9 EFCB3_HUMAN EF-hand calcium-binding domain-containing protein 3 EFCAB3 Homo sapiens (Human) calcium ion binding [GO:0005509] 0.5144 0.60235 EKKLSASQMAAFQDAYNFFYK 0 0 0 0 0 0 0 0 0 0 10.3422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N7C3 TRIMM_HUMAN Probable E3 ubiquitin-protein ligase TRIML2 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIML2) (SPRY domain-containing protein 6) (Tripartite motif family-like protein 2) TRIML2 SPRYD6 Homo sapiens (Human) innate immune response [GO:0045087]; protein ubiquitination [GO:0016567]; regulation of gene expression [GO:0010468]; response to retinoic acid [GO:0032526] cytoplasm [GO:0005737] identical protein binding [GO:0042802]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.61099 0.42786 SILTDEQER 0 0 0 0 0 0 0 0 0 10.2234 0 0 0 9.24937 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N7E2 CBLL2_HUMAN E3 ubiquitin-protein ligase CBLL2 (EC 2.3.2.27) (Cbl proto-oncogene-like protein 2) (RING-type E3 ubiquitin transferase ZNF645) (Zinc finger protein 645) (c-Cbl-like protein 2) CBLL2 ZNF645 Homo sapiens (Human) protein ubiquitination [GO:0016567]; regulation of cell adhesion [GO:0030155] cytoplasm [GO:0005737] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630] 0.96741 -2.3289 LSPCPPTRSPPPSTLHGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4339 11.2728 0 0 0 0 0 0 0 0 0 Q8N7J2 AMER2_HUMAN APC membrane recruitment protein 2 (Amer2) (Protein FAM123A) AMER2 FAM123A Homo sapiens (Human) ectoderm development [GO:0007398]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of canonical Wnt signaling pathway [GO:0060828]; Wnt signaling pathway [GO:0016055] plasma membrane [GO:0005886] "beta-catenin binding [GO:0008013]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]" 0.95233 -1.4604 GLAGTTIRATACHDSAK 9.83632 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N7K0 ZN433_HUMAN Zinc finger protein 433 ZNF433 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.9226 -1.1033 IVGERLFESK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.70058 0 0 0 0 0 0 0 Q8N7M0 DYLT5_HUMAN Dynein light chain Tctex-type 5 (Tctex1 domain-containing protein 1) DYNLT5 TCTEX1D1 Homo sapiens (Human) microtubule-based movement [GO:0007018] cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868] dynein intermediate chain binding [GO:0045505] 0.95356 -1.514 DLMIPRYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.49494 0 10.3427 0 Q8N7M2 ZN283_HUMAN Zinc finger protein 283 (Zinc finger protein HZF19) ZNF283 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.9641 -2.3838 ACSHGSK 0 0 9.195 0 0 0 0 0 0 0 0 11.0192 0 0 0 10.0375 0 8.51625 0 0 0 0 0 0 0 0 0 Q8N7P1 PLD5_HUMAN Inactive phospholipase D5 (Inactive PLD 5) (Inactive choline phosphatase 5) (Inactive phosphatidylcholine-hydrolyzing phospholipase D5) (PLDc) PLD5 Homo sapiens (Human) cytoplasm [GO:0005737]; intracellular organelle [GO:0043229]; membrane [GO:0016020] catalytic activity [GO:0003824] 0.88475 -0.24479 SRVPQTWSK 0 0 0 0 0 0 0 9.64409 0 0 11.1348 0 0 0 0 0 0 0 0 0 0 8.76894 0 0 0 0 0 Q8N7P7 YH007_HUMAN Uncharacterized protein FLJ40521 Homo sapiens (Human) 0.96964 -4.7217 DPKNDGCLLKQEPR 0 0 0 0 0 0 0 0 9.4124 0 0 0 0 0 0 0 0 9.78616 0 0 10.3074 0 0 0 0 0 0 Q8N7R7 CCYL1_HUMAN Cyclin-Y-like protein 1 CCNYL1 Homo sapiens (Human) flagellated sperm motility [GO:0030317]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of protein kinase activity [GO:0045859]; spermatogenesis [GO:0007283] plasma membrane [GO:0005886] cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; protein kinase binding [GO:0019901] 0.87041 0.065536 DITVEDMNEMER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.93587 0 0 0 0 0 0 0 0 0 Q8N7S6 ARI2O_HUMAN Uncharacterized protein ARIH2OS (Ariadne-2 homolog opposite strand protein) ARIH2OS C3orf71 Homo sapiens (Human) membrane [GO:0016020] 0.91427 -0.78134 IGAKRQR 0 0 0 0 0 0 8.48361 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N7U6 EFHB_HUMAN EF-hand domain-containing family member B (Cilia- and flagella-associated protein 21) EFHB CFAP21 Homo sapiens (Human) calcium ion transport [GO:0006816]; negative regulation of protein binding [GO:0032091]; regulation of calcineurin-NFAT signaling cascade [GO:0070884]; regulation of store-operated calcium entry [GO:2001256] axonemal microtubule [GO:0005879] calcium ion sensor activity [GO:0061891] 0.95495 -1.5659 GDGMIDK 0 0 0 0 0 0 0 11.3761 0 0 0 10.587 0 11.9056 0 0 0 0 8.96867 0 9.01374 8.19052 0 0 0 0 8.48627 Q8N7W2 BEND7_HUMAN BEN domain-containing protein 7 BEND7 C10orf30 Homo sapiens (Human) extracellular exosome [GO:0070062] DNA binding [GO:0003677] 0.95971 -1.8505 IYQRVGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.68506 0 0 0 0 0 0 0 0 0 0 0 0 Q8N7X0 ADGB_HUMAN Androglobin (Calpain-7-like protein) ADGB C6orf103 CAPN7L Homo sapiens (Human) cell differentiation [GO:0030154]; proteolysis [GO:0006508]; spermatogenesis [GO:0007283] motile cilium [GO:0031514] calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; heme binding [GO:0020037]; oxygen binding [GO:0019825] 0.96339 -2.1399 EIKDGKEVK 0 0 0 0 0 0 0 9.33648 0 0 0 0 10.4008 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N7X1 RMXL3_HUMAN "RNA-binding motif protein, X-linked-like-3" RBMXL3 CXorf55 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]" U12-type spliceosomal complex [GO:0005689] mRNA binding [GO:0003729]; snRNA binding [GO:0017069] 0.96867 -3.929 ALKAEFGK 0 0 0 0 0 0 0 0 0 11.3111 0 0 0 0 0 0 0 11.3713 0 0 0 0 0 0 0 0 0 Q8N7X2 STPG3_HUMAN Protein STPG3 (Sperm-tail PG-rich repeat-containing protein 3) STPG3 C9orf173 Homo sapiens (Human) cytoskeleton [GO:0005856] 0.38417 0.71715 YQVPSPSVRESSPHPHYSIGCK 0 0 0 0 0 0 0 0 10.3671 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N7Z5 ANR31_HUMAN Ankyrin repeat domain-containing protein 31 ANKRD31 Homo sapiens (Human) homologous chromosome pairing at meiosis [GO:0007129]; meiotic DNA double-strand break formation involved in reciprocal meiotic recombination [GO:0010780]; positive regulation of meiotic DNA double-strand break formation [GO:1903343] chromatin [GO:0000785]; nucleus [GO:0005634] 0.9695 -5.5151 GEFSGNDMNSK 0 0 0 0 0 0 0 0 0 10.3848 0 9.94598 0 0 0 11.2311 0 0 0 0 0 0 11.7144 0 0 0 0 Q8N806 UBR7_HUMAN Putative E3 ubiquitin-protein ligase UBR7 (EC 2.3.2.27) (N-recognin-7) (RING-type E3 ubiquitin transferase UBR7) UBR7 C14orf130 Homo sapiens (Human) protein ubiquitination [GO:0016567] ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.14187 1.0278 AGAEGAAGR 0 0 0 0 0 0 0 0 0 0 0 0 9.05189 0 0 0 9.39594 0 0 0 0 0 0 0 0 9.43673 0 Q8N807 PDILT_HUMAN Protein disulfide-isomerase-like protein of the testis PDILT Homo sapiens (Human) germ cell migration [GO:0008354]; protein folding [GO:0006457]; spermatid development [GO:0007286] endoplasmic reticulum [GO:0005783] protein disulfide isomerase activity [GO:0003756] 0.80112 0.23941 YQNHSTIIIAK 0 0 0 0 0 0 0 0 0 9.66156 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N813 PR23E_HUMAN Proline-rich protein 23E PRR23E C3orf56 Homo sapiens (Human) 0.96997 -5.2845 AAVEGPSRGAPYLKTCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.0022 0 0 0 0 10.2533 0 0 0 10.0752 0 0 Q8N815 CNTD1_HUMAN Cyclin N-terminal domain-containing protein 1 CNTD1 CNTD Homo sapiens (Human) reciprocal meiotic recombination [GO:0007131]; regulation of meiotic cell cycle [GO:0051445]; spermatogenesis [GO:0007283] chromosome [GO:0005694]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; site of double-strand break [GO:0035861] 0.88934 -0.44811 RESQNWRALK 0 0 0 0 0 0 0 0 0 12.5223 12.6208 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N819 PPM1N_HUMAN Probable protein phosphatase 1N (EC 3.1.3.16) PPM1N Homo sapiens (Human) negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of canonical Wnt signaling pathway [GO:0090263] cytosol [GO:0005829]; nucleus [GO:0005634] magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; myosin phosphatase activity [GO:0017018]; protein serine/threonine phosphatase activity [GO:0004722] 0.88485 -0.1356 EGREEEEEEEAGR 0 10.3824 0 0 8.83352 0 9.97928 0 0 0 0 0 0 0 0 0 0 11.2464 0 0 0 0 0 0 0 0 0 Q8N823 ZN611_HUMAN Zinc finger protein 611 ZNF611 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.94826 -1.3681 IGHTGEKPYK 0 0 0 10.7369 0 10.3242 11.877 11.8199 0 0 0 0 0 0 0 0 0 10.5181 0 0 0 0 0 0 0 0 0 Q8N831 TSYL6_HUMAN Testis-specific Y-encoded-like protein 6 (TSPY-like protein 6) TSPYL6 Homo sapiens (Human) nucleosome assembly [GO:0006334] chromatin [GO:0000785]; nucleus [GO:0005634] chromatin binding [GO:0003682]; histone binding [GO:0042393] 0.020408 1.5968 AIDEVNR 11.8638 0 11.7564 0 0 0 11.4273 0 11.4272 0 11.8308 0 9.51262 10.3267 8.96743 0 0 10.7745 0 8.67645 0 0 0 0 0 0 10.0913 Q8N841 TTLL6_HUMAN Tubulin polyglutamylase TTLL6 (EC 6.3.2.-) (Protein polyglutamylase TTLL6) (Tubulin--tyrosine ligase-like protein 6) TTLL6 TTL.6 Homo sapiens (Human) microtubule bundle formation [GO:0001578]; microtubule cytoskeleton organization [GO:0000226]; microtubule severing [GO:0051013]; positive regulation of cilium movement [GO:0003353]; protein polyglutamylation [GO:0018095]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296] 9+0 non-motile cilium [GO:0097731]; ciliary basal body [GO:0036064]; cilium [GO:0005929]; cytosol [GO:0005829]; microtubule [GO:0005874] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein-glutamic acid ligase activity [GO:0070739]; tubulin binding [GO:0015631]; tubulin-glutamic acid ligase activity [GO:0070740] 0.58647 0.46673 FFPRTWCLPADWGDLQTYSR 0 10.5574 10.4681 0 9.70503 0 10.9072 10.9636 0 0 0 10.2445 8.98382 0 0 0 0 0 0 0 0 9.40461 0 0 0 0 0 Q8N865 CG031_HUMAN Uncharacterized protein C7orf31 C7orf31 Homo sapiens (Human) centrosome [GO:0005813]; cytoplasm [GO:0005737] 0.8871 -0.34073 YEPPRVMGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.54616 0 0 0 0 0 0 Q8N878 FRMD1_HUMAN FERM domain-containing protein 1 FRMD1 Homo sapiens (Human) positive regulation of hippo signaling [GO:0035332] cytoplasmic side of apical plasma membrane [GO:0098592]; cytoskeleton [GO:0005856] 0.9469 -1.3573 LVYYTGCTWR 0 0 0 0 0 0 0 0 0 0 0 0 0 13.5671 0 0 0 0 0 0 0 0 0 9.9304 0 0 0 Q8N884 CGAS_HUMAN Cyclic GMP-AMP synthase (cGAMP synthase) (cGAS) (h-cGAS) (EC 2.7.7.86) (2'3'-cGAMP synthase) (Mab-21 domain-containing protein 1) CGAS C6orf150 MB21D1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; cAMP-mediated signaling [GO:0019933]; cellular response to exogenous dsRNA [GO:0071360]; cGMP-mediated signaling [GO:0019934]; cytosolic pattern recognition receptor signaling pathway [GO:0002753]; defense response to virus [GO:0051607]; determination of adult lifespan [GO:0008340]; DNA damage response [GO:0006974]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; negative regulation of innate immune response [GO:0045824]; paracrine signaling [GO:0038001]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cellular senescence [GO:2000774]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of type I interferon production [GO:0032481]; regulation of immunoglobulin production [GO:0002637]; regulation of innate immune response [GO:0045088]; regulation of T cell activation [GO:0050863] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of double-strand break [GO:0035861] "2',3'-cyclic GMP-AMP synthase activity [GO:0061501]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; enzyme activator activity [GO:0008047]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; molecular condensate scaffold activity [GO:0140693]; molecular function activator activity [GO:0140677]; molecular function inhibitor activity [GO:0140678]; nucleosome binding [GO:0031491]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; poly-ADP-D-ribose modification-dependent protein binding [GO:0160004]; protein homodimerization activity [GO:0042803]" 0.96246 -2.5177 EPALSRAGSCR 12.1244 12.091 0 0 0 11.4581 0 0 0 0 0 0 9.27041 0 0 0 0 0 0 0 0 0 0 11.2508 0 0 0 Q8N8A6 DDX51_HUMAN ATP-dependent RNA helicase DDX51 (EC 3.6.4.13) (DEAD box protein 51) DDX51 Homo sapiens (Human) rRNA processing [GO:0006364] membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.89871 -0.66463 ARERQQQR 0 0 10.4733 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.7295 0 0 10.3426 0 Q8N8C0 ZN781_HUMAN Zinc finger protein 781 ZNF781 Homo sapiens (Human) nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.8839 -0.13217 IHTGEKPYKCKQCWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1645 0 0 0 0 0 Q8N8D1 PDCD7_HUMAN Programmed cell death protein 7 (ES18) (hES18) PDCD7 Homo sapiens (Human) apoptotic process [GO:0006915]; response to glucocorticoid [GO:0051384]; RNA splicing [GO:0008380] nucleoplasm [GO:0005654]; U12-type spliceosomal complex [GO:0005689] 0.96263 -2.4471 ASAEASR 0 0 0 0 0 0 9.44402 0 0 0 0 0 0 0 0 0 11.3995 0 0 0 0 0 0 0 0 0 0 Q8N8E3 CE112_HUMAN Centrosomal protein of 112 kDa (Cep112) (Coiled-coil domain-containing protein 46) CEP112 CCDC46 Homo sapiens (Human) receptor localization to synapse [GO:0097120] centrosome [GO:0005813]; cytoplasm [GO:0005737]; inhibitory synapse [GO:0060077]; plasma membrane [GO:0005886] 0.87648 -0.0010915 SHSLSPTHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.20894 0 0 Q8N8H1 ZN321_HUMAN Putative protein ZNF321 (Zinc finger protein 321 pseudogene) ZNF321P ZNF321 Homo sapiens (Human) 0.84764 0.15414 LGSTHER 0 0 0 0 9.59289 0 0 0 10.7891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N8I0 SAM12_HUMAN Sterile alpha motif domain-containing protein 12 (SAM domain-containing protein 12) SAMD12 Homo sapiens (Human) transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] cytoplasmic side of plasma membrane [GO:0009898] 0.95897 -1.7161 ALLRLTDK 0 0 9.32423 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N8J6 ZN615_HUMAN Zinc finger protein 615 ZNF615 Homo sapiens (Human) nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.89787 -0.56207 CNECDKTFRK 0 0 0 0 0 0 0 9.13204 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N8K9 K1958_HUMAN Uncharacterized protein KIAA1958 KIAA1958 Homo sapiens (Human) 0.91227 -0.74948 AKLDCNRTR 0 0 0 0 0 0 8.9479 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N8L2 ZN491_HUMAN Zinc finger protein 491 ZNF491 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.82005 0.2188 AFHCVSSFHR 0 10.2488 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N8M0 NAT16_HUMAN Probable N-acetyltransferase 16 (EC 2.3.1.-) NAT16 C7orf52 Homo sapiens (Human) "acyltransferase activity, transferring groups other than amino-acyl groups [GO:0016747]" 0.95415 -1.5167 GLEWRVDSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.084 0 0 0 0 0 0 0 Q8N8Q9 NIPA2_HUMAN Magnesium transporter NIPA2 (Non-imprinted in Prader-Willi/Angelman syndrome region protein 2) NIPA2 Homo sapiens (Human) magnesium ion transport [GO:0015693] early endosome [GO:0005769]; membrane [GO:0016020]; plasma membrane [GO:0005886] magnesium ion transmembrane transporter activity [GO:0015095] 0.96114 -2.5603 NGNLTAF 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.66725 0 0 0 0 0 0 0 Q8N8R3 S2529_HUMAN Mitochondrial basic amino acids transporter (Carnitine/acylcarnitine translocase-like) (CACT-like) (Mitochondrial carnitine/acylcarnitine carrier protein CACL) (Mitochondrial ornithine transporter 3) (Solute carrier family 25 member 29) SLC25A29 C14orf69 ORNT3 Homo sapiens (Human) acyl carnitine transport [GO:0006844]; amino acid transport [GO:0006865]; L-arginine transmembrane transport [GO:1903826]; L-histidine transmembrane transport [GO:0089709]; L-lysine transmembrane transport [GO:1903401]; mitochondrial L-ornithine transmembrane transport [GO:1990575]; ornithine transport [GO:0015822] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] basic amino acid transmembrane transporter activity [GO:0015174]; high-affinity L-arginine transmembrane transporter activity [GO:0005289]; high-affinity lysine transmembrane transporter activity [GO:0005292] 0.89884 -0.66652 AEGWRVFTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.40242 0 0 0 0 Q8N8R7 AL14E_HUMAN ARL14 effector protein (ARF7 effector protein) ARL14EP ARF7EP C11orf46 Homo sapiens (Human) cytosol [GO:0005829]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] 0.96395 -2.4133 LTKNATAGSDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.36302 0 0 0 Q8N8S7 ENAH_HUMAN Protein enabled homolog ENAH MENA Homo sapiens (Human) actin polymerization or depolymerization [GO:0008154]; actin polymerization-dependent cell motility [GO:0070358]; axon guidance [GO:0007411] cell junction [GO:0030054]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886]; synapse [GO:0045202] actin binding [GO:0003779]; profilin binding [GO:0005522]; SH3 domain binding [GO:0017124]; WW domain binding [GO:0050699] 0.87427 0.03196 KIQDHQVVINCAIPK 0 0 0 0 0 0 10.464 0 0 0 0 0 0 0 0 0 0 0 0 0 8.89218 0 8.37513 0 0 0 0 Q8N8V2 GBP7_HUMAN Guanylate-binding protein 7 (EC 3.6.1.-) (EC 3.6.5.-) (GTP-binding protein 7) (GBP-7) (Guanine nucleotide-binding protein 7) (Guanylate-binding protein 4-like) GBP7 GBP4L Homo sapiens (Human) cytolysis in another organism [GO:0051715]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of type I interferon production [GO:0032480]; negative regulation of type III interferon production [GO:0034345]; positive regulation of viral genome replication [GO:0045070]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122] cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659] GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.96446 -2.3822 DKSQEFQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.35584 0 0 0 0 0 0 0 0 0 9.45687 0 0 Q8N8V4 ANS4B_HUMAN Ankyrin repeat and SAM domain-containing protein 4B (Harmonin-interacting ankyrin repeat-containing protein) (Harp) ANKS4B HARP Homo sapiens (Human) brush border assembly [GO:1904970]; cell differentiation [GO:0030154]; protein localization to microvillus [GO:1904106]; protein-containing complex assembly [GO:0065003]; response to endoplasmic reticulum stress [GO:0034976] brush border [GO:0005903]; endoplasmic reticulum membrane [GO:0005789]; microvillus [GO:0005902]; plasma membrane [GO:0005886] 0.91748 -0.86176 EQNECVALLDKAATAQNIMNPK 0 0 0 0 0 0 0 0 0 0 0 0 12.9354 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N8X9 MB213_HUMAN Protein mab-21-like 3 MAB21L3 C1orf161 Homo sapiens (Human) 0.91358 -0.78752 EQHWRYYTLQGTR 0 0 0 9.17165 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N8Y2 VA0D2_HUMAN V-type proton ATPase subunit d 2 (V-ATPase subunit d 2) (Vacuolar proton pump subunit d 2) ATP6V0D2 Homo sapiens (Human) regulation of macroautophagy [GO:0016241]; vacuolar acidification [GO:0007035]; vacuolar transport [GO:0007034] "apical plasma membrane [GO:0016324]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; phagocytic vesicle membrane [GO:0030670]; plasma membrane proton-transporting V-type ATPase complex [GO:0033181]; proton-transporting V-type ATPase, V0 domain [GO:0033179]; vacuolar proton-transporting V-type ATPase complex [GO:0016471]" "proton-transporting ATPase activity, rotational mechanism [GO:0046961]" 0.60366 0.44024 ETLYPTFGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.84632 0 0 0 0 0 Q8N8Y5 ZFP41_HUMAN Zinc finger protein 41 homolog (Zfp-41) ZFP41 Homo sapiens (Human) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] nucleus [GO:0005634] metal ion binding [GO:0046872]; sequence-specific double-stranded DNA binding [GO:1990837] 0.96725 -2.3382 AFAYSSCLIR 0 0 0 0 0 0 0 0 0 0 9.24294 0 0 0 0 0 0 0 0 11.5413 11.8019 11.5768 0 0 0 0 0 Q8N8Z3 PRR26_HUMAN Putative uncharacterized protein DIP2C-AS1 (DIP2C antisense RNA 1) (Proline-rich protein 26) DIP2C-AS1 C10orf108 PRR26 Homo sapiens (Human) 0.91992 -0.90585 ARDHGARGCGPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8212 Q8N8Z6 DCBD1_HUMAN "Discoidin, CUB and LCCL domain-containing protein 1" DCBLD1 Homo sapiens (Human) membrane [GO:0016020] signaling receptor activity [GO:0038023] 0.89834 -0.61809 DVAGDISGNMVDGYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.99365 0 0 0 0 0 0 0 Q8N8Z8 ZN441_HUMAN Zinc finger protein 441 ZNF441 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.96786 -3.819 IHERVHTGEKPYK 0 0 0 0 0 0 0 0 0 9.3226 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N944 AMER3_HUMAN APC membrane recruitment protein 3 (Amer3) (Protein FAM123C) AMER3 FAM123C Homo sapiens (Human) regulation of canonical Wnt signaling pathway [GO:0060828]; Wnt signaling pathway [GO:0016055] plasma membrane [GO:0005886] "beta-catenin binding [GO:0008013]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]" 0.93163 -1.2706 ALGGATQGTGTLSRDASR 0 0 0 0 9.28914 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N954 GPT11_HUMAN G patch domain-containing protein 11 (Coiled-coil domain-containing protein 75) GPATCH11 CCDC75 CENP-Y Homo sapiens (Human) kinetochore [GO:0000776] nucleic acid binding [GO:0003676] 0.96341 -2.1451 AEEKLESYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.55783 0 9.24479 0 0 0 0 Q8N957 ANKF1_HUMAN Ankyrin repeat and fibronectin type-III domain-containing protein 1 ANKFN1 Homo sapiens (Human) establishment of mitotic spindle orientation [GO:0000132]; regulation of establishment of bipolar cell polarity [GO:0061172] spindle [GO:0005819] 0.95955 -1.8171 AWEWRYR 0 0 0 8.88652 0 0 0 0 11.7397 10.3661 0 0 0 0 0 0 0 0 0 0 0 10.0572 0 9.8775 8.91833 0 0 Q8N960 CE120_HUMAN Centrosomal protein of 120 kDa (Cep120) (Coiled-coil domain-containing protein 100) CEP120 CCDC100 Homo sapiens (Human) astral microtubule organization [GO:0030953]; centrosome cycle [GO:0007098]; cerebral cortex development [GO:0021987]; interkinetic nuclear migration [GO:0022027]; neurogenesis [GO:0022008]; positive regulation of centriole elongation [GO:1903724]; positive regulation of centrosome duplication [GO:0010825]; positive regulation of cilium assembly [GO:0045724]; positive regulation of establishment of protein localization [GO:1904951] centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737] 0.96992 -4.3315 ALHQHRLQR 0 0 0 0 0 0 8.58886 0 0 0 0 11.5641 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N961 ABTB2_HUMAN Ankyrin repeat and BTB/POZ domain-containing protein 2 ABTB2 Homo sapiens (Human) cellular response to toxic substance [GO:0097237] protein heterodimerization activity [GO:0046982] 0.95022 -1.3818 CPRLPELEEFPWTEGDVAR 0 0 0 0 0 9.29689 0 0 0 0 0 0 0 0 9.74025 0 0 0 0 0 0 0 0 0 9.00056 0 0 Q8N987 NECA1_HUMAN N-terminal EF-hand calcium-binding protein 1 (EF-hand calcium-binding protein 1) (Neuronal calcium-binding protein 1) NECAB1 EFCBP1 Homo sapiens (Human) blastocyst hatching [GO:0001835]; regulation of amyloid precursor protein biosynthetic process [GO:0042984] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654] calcium ion binding [GO:0005509]; identical protein binding [GO:0042802] 0.87117 0.037766 QGPAKPEVLSIQWPGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5542 0 0 0 0 0 0 0 0 0 0 0 Q8N988 ZN557_HUMAN Zinc finger protein 557 ZNF557 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.88425 -0.29834 EFRTQSIFTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5463 Q8N998 CCD89_HUMAN Coiled-coil domain-containing protein 89 (Bc8 orange-interacting protein) CCDC89 BOIP Homo sapiens (Human) cytoplasm [GO:0005737]; nucleus [GO:0005634] 0.95813 -1.6866 LEIANEDRK 9.01061 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N9B5 JMY_HUMAN Junction-mediating and -regulatory protein JMY Homo sapiens (Human) 'de novo' actin filament nucleation [GO:0070060]; actin polymerization-dependent cell motility [GO:0070358]; Arp2/3 complex-mediated actin nucleation [GO:0034314]; cellular response to starvation [GO:0009267]; DNA repair [GO:0006281]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; regulation of transcription by RNA polymerase II [GO:0006357] autophagosome membrane [GO:0000421]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytoskeleton [GO:0005856]; endomembrane system [GO:0012505]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] actin binding [GO:0003779]; Arp2/3 complex binding [GO:0071933]; microtubule binding [GO:0008017]; transcription coactivator activity [GO:0003713] 0.96805 -3.0012 ADQKKFGK 0 0 0 0 0 0 0 10.8764 10.6092 0 0 0 0 0 0 0 0 0 0 9.97885 0 0 0 0 0 0 9.53683 Q8N9B8 RGF1A_HUMAN Ras-GEF domain-containing family member 1A RASGEF1A Homo sapiens (Human) cell migration [GO:0016477]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Ras protein signal transduction [GO:0046579]; Ras protein signal transduction [GO:0007265] cytosol [GO:0005829]; plasma membrane [GO:0005886] guanyl-nucleotide exchange factor activity [GO:0005085] 0.89861 -0.63492 EKIVIPVFNLFVK 0 0 0 0 0 0 0 0 9.66085 0 10.481 10.3725 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N9C0 IGS22_HUMAN Immunoglobulin superfamily member 22 (IgSF22) IGSF22 Homo sapiens (Human) 0.96938 -3.1873 FVSNLKNVRVK 0 0 0 0 0 0 0 0 10.4059 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N9F0 NAT8L_HUMAN N-acetylaspartate synthetase (NAA synthetase) (EC 2.3.1.17) (Camello-like protein 3) (N-acetyltransferase 8-like protein) NAT8L CML3 Homo sapiens (Human) aspartate family amino acid metabolic process [GO:0009066] cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739] aspartate N-acetyltransferase activity [GO:0017188] 0.96388 -2.2541 GLRQHPR 0 0 0 0 11.0554 0 0 0 0 10.5743 11.6507 0 0 0 0 0 0 12.5279 0 0 0 0 0 0 0 0 0 Q8N9F7 GDPD1_HUMAN Lysophospholipase D GDPD1 (EC 3.1.4.-) (Glycerophosphodiester phosphodiesterase 4) (Glycerophosphodiester phosphodiesterase domain-containing protein 1) GDPD1 GDE4 Homo sapiens (Human) glycerophospholipid catabolic process [GO:0046475]; N-acylethanolamine metabolic process [GO:0070291] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471] lysophospholipase activity [GO:0004622]; metal ion binding [GO:0046872]; phosphoric diester hydrolase activity [GO:0008081] 0.76378 0.28925 VNNNVLIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.84167 0 0 0 0 0 Q8N9F8 ZN454_HUMAN Zinc finger protein 454 ZNF454 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837] 0.89834 -0.56085 AEIPEEELDQWTIKER 0 0 0 0 10.1949 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.59373 0 0 0 0 0 0 0 Q8N9G6 YJ012_HUMAN Putative UPF0607 protein FLJ37424 Homo sapiens (Human) 0.97007 -3.2572 LPKTEVSAEEPK 0 0 0 0 0 0 0 0 0 0 11.9066 12.1388 0 0 9.94875 0 0 0 0 0 0 0 0 0 0 0 0 Q8N9H8 MUT7_HUMAN Exonuclease mut-7 homolog (EC 3.1.-.-) (Exonuclease 3'-5' domain-containing protein 3) EXD3 HBE269 Homo sapiens (Human) nucleobase-containing compound metabolic process [GO:0006139] 3'-5' exonuclease activity [GO:0008408]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676] 0.95889 -1.7161 QLQARAVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.67437 0 0 0 0 0 0 0 0 0 0 Q8N9I0 SYT2_HUMAN Synaptotagmin-2 (Synaptotagmin II) (SytII) SYT2 Homo sapiens (Human) calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cell differentiation [GO:0030154]; cellular response to calcium ion [GO:0071277]; positive regulation of dendrite extension [GO:1903861]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; synaptic vesicle endocytosis [GO:0048488] axon [GO:0030424]; chromaffin granule membrane [GO:0042584]; clathrin-coated endocytic vesicle membrane [GO:0030669]; dense core granule [GO:0031045]; plasma membrane [GO:0005886]; synaptic vesicle membrane [GO:0030672] "calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; clathrin binding [GO:0030276]; inositol 1,3,4,5 tetrakisphosphate binding [GO:0043533]; phosphatidylserine binding [GO:0001786]; syntaxin binding [GO:0019905]" 0.90764 -0.74086 DLQGGEKEEPEK 0 0 0 0 0 0 0 0 0 0 9.83093 10.1476 9.04562 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N9I5 FADS6_HUMAN Fatty acid desaturase 6 (EC 1.14.19.-) FADS6 FP18279 Homo sapiens (Human) fatty acid biosynthetic process [GO:0006633]; lipid metabolic process [GO:0006629] membrane [GO:0016020] "oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]" 0.84217 0.14896 EPTEPMEPTEPMEPTEPMEPAR 0 0 10.8855 10.062 0 0 0 0 0 10.8738 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N9K5 ZN565_HUMAN Zinc finger protein 565 ZNF565 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.85323 0.10631 AGQIVLK 0 0 0 0 0 0 0 0 9.23434 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N9N5 BANP_HUMAN Protein BANP (BEN domain-containing protein 1) (Btg3-associated nuclear protein) (Scaffold/matrix-associated region-1-binding protein) BANP BEND1 SMAR1 Homo sapiens (Human) cell cycle [GO:0007049]; chromatin organization [GO:0006325]; negative regulation of protein catabolic process [GO:0042177]; protein localization to nucleus [GO:0034504] nuclear body [GO:0016604]; nucleoplasm [GO:0005654] DNA binding [GO:0003677]; identical protein binding [GO:0042802] 0.96931 -3.2019 EVQAVSNLSGQGKHGK 10.3132 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.11943 0 0 0 0 0 0 0 0 Q8N9N7 LRC57_HUMAN Leucine-rich repeat-containing protein 57 LRRC57 Homo sapiens (Human) extracellular exosome [GO:0070062]; membrane [GO:0016020] 0.93338 -1.2841 ISCCPRLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.41933 0 0 0 0 0 0 Q8N9P0 YF006_HUMAN Putative uncharacterized protein FLJ36797 Homo sapiens (Human) 0.96131 -2.5603 SVGGPQK 0 0 0 0 0 0 0 0 8.67871 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N9P6 CI163_HUMAN Uncharacterized protein C9orf163 C9orf163 Homo sapiens (Human) 0.88569 -0.37478 FLTCLNR 0 0 0 0 0 0 0 0 0 10.5075 0 0 0 0 0 0 0 0 9.8839 0 0 0 0 0 0 0 0 Q8N9S9 SNX31_HUMAN Sorting nexin-31 SNX31 Homo sapiens (Human) intracellular protein transport [GO:0006886] early endosome [GO:0005769]; protein-containing complex [GO:0032991] phosphatidylinositol binding [GO:0035091] 0.82299 0.21538 DYSSFLSR 0 0 0 0 9.75931 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N9T8 KRI1_HUMAN Protein KRI1 homolog KRI1 Homo sapiens (Human) "endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]" 90S preribosome [GO:0030686]; nucleolus [GO:0005730] RNA binding [GO:0003723] 0.96885 -6.5505 AQNSWKK 0 11.1573 0 0 13.1392 0 0 9.0354 0 0 0 12.1119 0 0 0 10.6372 11.98 0 0 0 0 0 0 0 0 0 0 Q8N9U0 TAC2N_HUMAN Tandem C2 domains nuclear protein (Membrane targeting tandem C2 domain-containing protein 1) (Tandem C2 protein in nucleus) (Tac2-N) TC2N C14orf47 MTAC2D1 Homo sapiens (Human) nucleus [GO:0005634] 0.92423 -0.99513 LSYIQPR 9.46318 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.3759 Q8N9U9 SPOT1_HUMAN Putative uncharacterized protein SPANXA2-OT1 SPANXA2-OT1 CXorf18 Homo sapiens (Human) 0.8981 -0.56805 TAFGGGGR 0 0 0 0 0 0 0 0 0 0 0 0 0 8.68134 0 0 0 0 0 0 0 0 8.59924 0 0 0 0 Q8N9V3 WSDU1_HUMAN "WD repeat, SAM and U-box domain-containing protein 1" WDSUB1 WDSAM1 Homo sapiens (Human) protein ubiquitination [GO:0016567] ubiquitin-protein transferase activity [GO:0004842] 0.77204 0.27295 EAMENWISK 0 0 0 0 0 8.95364 10.7855 0 0 10.4851 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N9V6 ANR53_HUMAN Ankyrin repeat domain-containing protein 53 ANKRD53 Homo sapiens (Human) cell division [GO:0051301]; mitotic metaphase plate congression [GO:0007080]; positive regulation of microtubule polymerization [GO:0031116]; regulation of mitotic cytokinesis [GO:1902412]; regulation of mitotic spindle organization [GO:0060236] cytoplasm [GO:0005737]; spindle [GO:0005819]; spindle pole [GO:0000922] 0.96896 -3.8964 ADPSPSK 0 0 0 0 0 0 0 0 0 0 0 0 9.25835 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8N9V7 TOPZ1_HUMAN Protein TOPAZ1 (Testis- and ovary-specific PAZ domain-containing protein 1) TOPAZ1 C3orf77 Homo sapiens (Human) apoptotic process [GO:0006915]; ectopic germ cell programmed cell death [GO:0035234]; ncRNA transcription [GO:0098781]; spermatocyte division [GO:0048137] cytosol [GO:0005829] 0.96889 -3.9049 EAELPLQTER 0 9.39451 0 10.0761 0 0 9.24767 0 0 13.6147 12.0446 0 0 0 0 0 0 9.47413 0 0 0 0 0 0 10.9607 10.2363 8.62231 Q8N9W4 GG6L2_HUMAN Golgin subfamily A member 6-like protein 2 GOLGA6L2 Homo sapiens (Human) 0.96826 -9.2737 ALSAVSTWHKK 0 0 0 9.89356 10.2124 0 0 0 0 12.3101 11.866 9.81925 0 0 9.52213 0 0 0 0 0 0 10.5525 0 0 0 0 0 Q8N9W6 BOLL_HUMAN Protein boule-like BOLL BOULE Homo sapiens (Human) 3'-UTR-mediated mRNA stabilization [GO:0070935]; cell differentiation [GO:0030154]; meiotic cell cycle [GO:0051321]; positive regulation of translational initiation [GO:0045948]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737] identical protein binding [GO:0042802]; mRNA 3'-UTR binding [GO:0003730]; translation activator activity [GO:0008494] 0.87684 -0.00069193 IFVGGIDFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.90159 0 0 0 0 0 0 0 0 0 0 0 0 Q8N9Z2 CC71L_HUMAN Coiled-coil domain-containing protein 71L CCDC71L C7orf74 Homo sapiens (Human) 0.9696 -3.5342 ALGDAFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.10064 9.04423 0 0 Q8N9Z9 LMTD1_HUMAN Lamin tail domain-containing protein 1 (Intermediate filament tail domain-containing protein 1) LMNTD1 IFLTD1 Homo sapiens (Human) cell population proliferation [GO:0008283] cytoplasm [GO:0005737]; intermediate filament [GO:0005882]; nuclear envelope [GO:0005635] 0.96262 -2.0947 EKQDQPKK 0 0 0 0 0 0 0 0 0 9.03452 9.15795 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NA03 FSIP1_HUMAN Fibrous sheath-interacting protein 1 FSIP1 HSD10 Homo sapiens (Human) 0.9694 -3.1415 EDHSESSNTENR 14.7166 14.7469 15.2666 11.2864 10.6264 10.6312 14.0905 14.4659 14.2011 9.61152 14.5885 14.7676 12.6278 12.849 12.7063 13.4605 13.3723 13.7189 8.43459 0 8.98638 0 0 0 0 9.29218 0 Q8NA29 NLS1_HUMAN Sodium-dependent lysophosphatidylcholine symporter 1 (NLS1) (Sodium-dependent LPC symporter 1) (Major facilitator superfamily domain-containing protein 2A) (HsMFSD2A) (MFSD2a) MFSD2A MFSD2 NLS1 HMFN0656 PP9177 UNQ300/PRO341 Homo sapiens (Human) brain development [GO:0007420]; carbohydrate transport [GO:0008643]; cellular response to starvation [GO:0009267]; cognition [GO:0050890]; energy homeostasis [GO:0097009]; establishment of blood-brain barrier [GO:0060856]; fatty acid transport [GO:0015908]; hippocampus development [GO:0021766]; lipid transport across blood-brain barrier [GO:1990379]; long-chain fatty acid transport [GO:0015909]; lysophospholipid translocation [GO:0140329]; lysophospholipid transport [GO:0051977]; maintenance of blood-brain barrier [GO:0035633]; motor behavior [GO:0061744]; negative regulation of fatty acid beta-oxidation [GO:0031999]; organic substance transport [GO:0071702]; phosphatidylcholine biosynthetic process [GO:0006656]; photoreceptor cell morphogenesis [GO:0008594]; photoreceptor cell outer segment organization [GO:0035845]; positive regulation of cell growth [GO:0030307]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of dendrite development [GO:0050773]; regulation of multicellular organism growth [GO:0040014]; regulation of neuron projection arborization [GO:0150011]; regulation of phosphatidylcholine metabolic process [GO:0150172]; regulation of phosphatidylethanolamine metabolic process [GO:0150175]; regulation of phosphatidylserine metabolic process [GO:0150178]; retina morphogenesis in camera-type eye [GO:0060042]; retinal pigment epithelium development [GO:0003406]; transcytosis [GO:0045056]; transport across blood-brain barrier [GO:0150104]; very-low-density lipoprotein particle assembly [GO:0034379] endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886] fatty acid transmembrane transporter activity [GO:0015245]; long-chain fatty acid transporter activity [GO:0005324]; lysophosphatidylcholine flippase activity [GO:0140348]; lysophospholipid:sodium symporter activity [GO:0051978]; oleate transmembrane transporter activity [GO:1901480]; phospholipid transporter activity [GO:0005548] 0.82013 0.21938 LVMSHGPYIK 10.332 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NA31 TERB1_HUMAN Telomere repeats-binding bouquet formation protein 1 (Coiled-coil domain-containing protein 79) TERB1 CCDC79 Homo sapiens (Human) double-strand break repair involved in meiotic recombination [GO:1990918]; homologous chromosome pairing at meiosis [GO:0007129]; meiotic attachment of telomere to nuclear envelope [GO:0070197]; meiotic telomere clustering [GO:0045141] "chromosome, telomeric region [GO:0000781]; nuclear inner membrane [GO:0005637]; shelterin complex [GO:0070187]" 0.88629 -0.35649 EGNEEEIQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9327 10.5561 0 Q8NA42 ZN383_HUMAN Zinc finger protein 383 ZNF383 HSD17 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] cytoplasm [GO:0005737]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654] DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96122 -2.5946 AFTQSSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.90385 0 0 0 8.71826 8.64706 0 0 0 0 Q8NA54 IQUB_HUMAN IQ and ubiquitin-like domain-containing protein IQUB Homo sapiens (Human) cilium assembly [GO:0060271]; smoothened signaling pathway [GO:0007224] acrosomal vesicle [GO:0001669]; cytoskeleton [GO:0005856]; motile cilium [GO:0031514] 0.88279 -0.077004 EVDLMMRGVK 0 0 0 0 0 0 0 0 0 0 0 0 9.89582 0 0 0 10.3829 0 0 0 0 0 0 0 10.0853 0 0 Q8NA57 CL050_HUMAN Uncharacterized protein C12orf50 C12orf50 Homo sapiens (Human) poly(A)+ mRNA export from nucleus [GO:0016973] 0.87994 0.017088 ISCIFYHSKPR 0 10.8631 10.9667 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NA58 PNDC1_HUMAN Poly(A)-specific ribonuclease PNLDC1 (EC 3.1.13.4) (PARN-like domain-containing protein 1) (Poly(A)-specific ribonuclease domain-containing protein 1) (HsPNLDC1) PNLDC1 Homo sapiens (Human) "blastocyst formation [GO:0001825]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; piRNA processing [GO:0034587]; spermatogenesis [GO:0007283]" cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789] metal ion binding [GO:0046872]; poly(A)-specific ribonuclease activity [GO:0004535]; RNA binding [GO:0003723] 0.9525 -1.4574 RLTRSQFLLLTNK 0 0 9.10127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.48595 0 0 0 0 0 0 0 0 0 Q8NA61 CBY2_HUMAN Protein chibby homolog 2 (Spermatid-associated protein) CBY2 SPERT Homo sapiens (Human) cytoplasmic vesicle [GO:0031410] identical protein binding [GO:0042802] 0.84975 0.11254 ECMLQEENKSLR 0 0 0 0 0 0 0 0 0 0 9.46301 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NA69 TEX45_HUMAN Testis-expressed protein 45 TEX45 C19orf45 Homo sapiens (Human) 0.92178 -1.1369 QFQALPGPPALRCKR 0 10.6788 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NA75 DC4L2_HUMAN DDB1- and CUL4-associated factor 4-like protein 2 (WD repeat-containing protein 21C) DCAF4L2 WDR21C Homo sapiens (Human) Cul4-RING E3 ubiquitin ligase complex [GO:0080008] 0.96255 -2.4725 LLEEADKQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.8058 0 10.271 0 0 0 0 Q8NA82 MARHA_HUMAN Probable E3 ubiquitin-protein ligase MARCHF10 (EC 2.3.2.27) (Membrane-associated RING finger protein 10) (Membrane-associated RING-CH protein X) (MARCH-X) (RING finger protein 190) (RING-type E3 ubiquitin transferase MARCHF10) MARCHF10 MARCH10 RNF190 Homo sapiens (Human) protein ubiquitination [GO:0016567] transferase activity [GO:0016740]; zinc ion binding [GO:0008270] 0.89039 -0.48237 ASGDRSR 9.33266 0 0 0 0 0 0 0 0 0 0 0 0 9.37695 0 0 0 0 0 0 8.68548 8.73752 9.31139 0 0 0 0 Q8NAA4 A16L2_HUMAN Protein Atg16l2 (APG16-like 2) (Autophagy-related protein 16-2) (WD repeat-containing protein 80) ATG16L2 WDR80 Homo sapiens (Human) autophagosome assembly [GO:0000045]; macroautophagy [GO:0016236]; negative stranded viral RNA replication [GO:0039689]; protein lipidation [GO:0006497]; protein transport [GO:0015031] Atg12-Atg5-Atg16 complex [GO:0034274]; autophagosome membrane [GO:0000421]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; phagophore assembly site membrane [GO:0034045] 0.96999 -5.1566 IRFWDSR 0 0 0 0 0 0 0 0 0 9.6626 0 0 0 0 0 0 0 0 9.44481 0 0 0 0 0 0 0 0 Q8NAA5 LR75A_HUMAN Leucine-rich repeat-containing protein 75A (Leucine-rich repeat-containing protein FAM211A) LRRC75A C17orf76 FAM211A Homo sapiens (Human) cytoplasm [GO:0005737] 0.83993 0.18487 VGMVQELLR 0 0 0 0 0 0 0 0 0 0 8.99424 0 0 0 0 0 0 0 0 0 0 0 8.49989 0 0 0 0 Q8NAB2 KBTB3_HUMAN Kelch repeat and BTB domain-containing protein 3 (BTB and kelch domain-containing protein 3) KBTBD3 BKLHD3 Homo sapiens (Human) 0.83333 0.19884 YLPHLIEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.5283 0 0 0 0 0 0 0 0 0 Q8NAF0 ZN579_HUMAN Zinc finger protein 579 ZNF579 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; transcription cis-regulatory region binding [GO:0000976]" 0.96156 -2.5603 GGAGAPR 0 0 0 0 0 0 0 0 0 11.2981 0 0 10.513 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NAM6 ZSCA4_HUMAN Zinc finger and SCAN domain-containing protein 4 (Zinc finger protein 494) ZSCAN4 ZNF494 Homo sapiens (Human) negative regulation of mitotic recombination [GO:0045950]; regulation of transcription by RNA polymerase II [GO:0006357]; telomere maintenance via telomere lengthening [GO:0010833] "chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]" "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.42932 0.6593 TSYRQSSTYHRHMR 0 0 0 0 0 0 0 12.9106 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NAP3 ZBT38_HUMAN Zinc finger and BTB domain-containing protein 38 ZBTB38 Homo sapiens (Human) DNA damage response [GO:0006974]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA replication [GO:0006275]; regulation of DNA-templated transcription [GO:0006355] blood microparticle [GO:0072562]; chromosome [GO:0005694]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; methyl-CpG binding [GO:0008327]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.88386 -0.10666 TTNIAEETSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2724 0 0 0 0 0 9.57442 0 0 0 0 0 Q8NAP8 ZBT8B_HUMAN Zinc finger and BTB domain-containing protein 8B ZBTB8B Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]" 0.96456 -2.4317 LLGELNEQRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7538 0 0 0 Q8NAQ8 YP023_HUMAN Putative uncharacterized protein FLJ34945 Homo sapiens (Human) 0.60542 0.43907 DGGAVAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.8638 9.38221 9.29274 0 0 0 0 Q8NAT1 PMGT2_HUMAN "Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 (POMGnT2) (EC 2.4.1.312) (Extracellular O-linked N-acetylglucosamine transferase-like) (Glycosyltransferase-like domain-containing protein 2)" POMGNT2 AGO61 C3orf39 EOGTL GTDC2 Homo sapiens (Human) neuron migration [GO:0001764]; protein O-linked glycosylation [GO:0006493]; protein O-linked mannosylation [GO:0035269] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789] acetylglucosaminyltransferase activity [GO:0008375]; protein O-acetylglucosaminyltransferase activity [GO:0097363] 0.9669 -2.3188 EVPRHLCCR 0 0 0 0 0 0 0 0 0 0 12.5879 0 0 0 0 0 0 0 8.9389 0 0 0 0 0 0 0 0 Q8NAT2 TDRD5_HUMAN Tudor domain-containing protein 5 TDRD5 TUDOR3 Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; P granule organization [GO:0030719]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283] chromatoid body [GO:0033391]; pi-body [GO:0071546]; synapse [GO:0045202] 0.88713 -0.35373 ISEDKWWYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.22028 0 0 0 0 0 0 0 0 0 0 0 Q8NAV1 PR38A_HUMAN Pre-mRNA-splicing factor 38A PRPF38A Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]" nucleoplasm [GO:0005654]; nucleus [GO:0005634]; precatalytic spliceosome [GO:0071011]; U2-type precatalytic spliceosome [GO:0071005] RNA binding [GO:0003723] 0.96174 -2.5603 VPSPDHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.95174 8.82251 0 0 0 0 0 0 0 Q8NAV2 CH058_HUMAN Uncharacterized protein C8orf58 C8orf58 Homo sapiens (Human) 0.73326 0.33002 LASKPER 0 0 0 0 0 0 0 0 0 0 0 0 8.3821 9.09376 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NB12 SMYD1_HUMAN Histone-lysine N-methyltransferase SMYD1 (EC 2.1.1.354) (SET and MYND domain-containing protein 1) SMYD1 Homo sapiens (Human) heart development [GO:0007507]; histone lysine methylation [GO:0034968]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of myotube differentiation [GO:0010831]; skeletal muscle cell differentiation [GO:0035914] cytoplasm [GO:0005737]; nucleus [GO:0005634] DNA binding [GO:0003677]; histone H3K4 trimethyltransferase activity [GO:0140999]; metal ion binding [GO:0046872]; transcription corepressor activity [GO:0003714] 0.96933 -5.6424 IMWRVER 0 0 0 0 0 8.95364 0 0 0 0 0 0 0 0 9.93756 0 0 0 0 0 0 9.67016 0 0 0 0 0 Q8NB14 UBP38_HUMAN Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.4.19.12) (Deubiquitinating enzyme 38) (HP43.8KD) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) USP38 KIAA1891 Homo sapiens (Human) protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] cytosol [GO:0005829]; nucleus [GO:0005634] cysteine-type deubiquitinase activity [GO:0004843]; cysteine-type endopeptidase activity [GO:0004197] 0.88388 -0.25689 AAVLTETPR 0 14.3711 0 0 0 0 14.5925 0 0 14.8797 14.8288 0 0 0 0 0 0 11.3122 0 0 0 0 9.39838 0 0 0 10.0547 Q8NB16 MLKL_HUMAN Mixed lineage kinase domain-like protein (hMLKL) MLKL Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; defense response to virus [GO:0051607]; execution phase of necroptosis [GO:0097528]; necroptotic process [GO:0070266]; necroptotic signaling pathway [GO:0097527]; protein homotrimerization [GO:0070207]; protein phosphorylation [GO:0006468] cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877] 0.88298 -0.31356 AFQMLRR 0 0 0 0 0 0 0 0 0 0 0 0 10.7378 10.1746 0 0 0 0 0 0 0 8.9053 0 0 0 0 0 Q8NB25 F184A_HUMAN Protein FAM184A FAM184A C6orf60 Homo sapiens (Human) centriolar satellite [GO:0034451]; extracellular space [GO:0005615]; P-body [GO:0000932] 0.90083 -0.6929 AMLTERDQIIK 12.4308 0 0 8.87698 9.88416 0 8.83826 0 12.1609 0 0 0 11.9827 0 11.943 0 13.577 0 0 0 0 0 0 0 0 0 9.52736 Q8NB49 AT11C_HUMAN Phospholipid-transporting ATPase IG (EC 7.6.2.1) (ATPase IQ) (ATPase class VI type 11C) (P4-ATPase flippase complex alpha subunit ATP11C) ATP11C ATPIG ATPIQ Homo sapiens (Human) monoatomic ion transmembrane transport [GO:0034220]; phospholipid translocation [GO:0045332] early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; lysosomal membrane [GO:0005765]; phospholipid-translocating ATPase complex [GO:1990531]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled intramembrane lipid transporter activity [GO:0140326]; magnesium ion binding [GO:0000287]; phosphatidylethanolamine flippase activity [GO:0090555]; phosphatidylserine flippase activity [GO:0140346]; phosphatidylserine floppase activity [GO:0090556] 0.88777 -0.4004 ALCLCHTVEIK 0 0 11.9697 0 0 0 0 0 0 0 0 0 0 9.25883 0 0 0 0 0 0 9.29632 0 0 9.54388 0 0 0 Q8NB50 ZFP62_HUMAN Zinc finger protein 62 homolog (Zfp-62) ZFP62 Homo sapiens (Human) nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.88391 -0.20591 CNECGKAFNIR 0 0 0 0 0 0 9.50323 9.65989 0 10.9009 0 0 0 0 0 0 0 8.88746 0 0 0 0 0 0 0 10.8339 0 Q8NB66 UN13C_HUMAN Protein unc-13 homolog C (Munc13-3) UNC13C Homo sapiens (Human) "chemical synaptic transmission [GO:0007268]; dense core granule priming [GO:0061789]; negative regulation of synaptic plasticity [GO:0031914]; neuromuscular junction development [GO:0007528]; presynaptic dense core vesicle exocytosis [GO:0099525]; synaptic transmission, glutamatergic [GO:0035249]; synaptic vesicle docking [GO:0016081]; synaptic vesicle maturation [GO:0016188]; synaptic vesicle priming [GO:0016082]" calyx of Held [GO:0044305]; neuromuscular junction [GO:0031594]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; presynaptic active zone [GO:0048786]; presynaptic active zone cytoplasmic component [GO:0098831]; presynaptic membrane [GO:0042734]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195] calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; diacylglycerol binding [GO:0019992]; phospholipid binding [GO:0005543]; syntaxin-1 binding [GO:0017075] 0.96975 -5.9624 DLGQLSKLKEHMIR 0 0 9.88713 11.1511 0 0 9.00279 0 0 0 0 0 0 9.50305 0 0 0 0 0 0 10.4016 0 0 0 0 10.0377 0 Q8NB78 KDM1B_HUMAN Lysine-specific histone demethylase 2 (EC 1.14.99.66) (Flavin-containing amine oxidase domain-containing protein 1) (Lysine-specific histone demethylase 1B) KDM1B AOF1 C6orf193 LSD2 Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression by genomic imprinting [GO:0006349]; transcription initiation-coupled chromatin remodeling [GO:0045815] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634] chromatin binding [GO:0003682]; FAD binding [GO:0071949]; FAD-dependent H3K4me/H3K4me3 demethylase activity [GO:0140682]; flavin adenine dinucleotide binding [GO:0050660]; histone binding [GO:0042393]; histone demethylase activity [GO:0032452]; oxidoreductase activity [GO:0016491]; zinc ion binding [GO:0008270] 0.91615 -0.76535 QLHNFGIKVTVLEAK 0 12.572 12.5545 12.0505 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NB90 AFG2A_HUMAN ATPase family gene 2 protein homolog A (EC 3.6.4.10) (AFG2 AAA ATPase homolog A) (Ribosome biogenesis protein SPATA5) (Spermatogenesis-associated factor protein) (Spermatogenesis-associated protein 5) AFG2A SPAF SPATA5 Homo sapiens (Human) brain development [GO:0007420]; cell differentiation [GO:0030154]; ribosomal large subunit biogenesis [GO:0042273]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; spindle [GO:0005819] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; preribosome binding [GO:1990275] 0.83545 0.19384 ALMRPGR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.09376 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NB91 FANCB_HUMAN Fanconi anemia group B protein (Protein FACB) (Fanconi anemia-associated polypeptide of 95 kDa) (FAAP95) FANCB Homo sapiens (Human) interstrand cross-link repair [GO:0036297]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein monoubiquitination [GO:0006513]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414] chromatin [GO:0000785]; Fanconi anaemia nuclear complex [GO:0043240]; nucleoplasm [GO:0005654] 0.96329 -2.1218 FCCTVLLQIMERESGNCPK 0 10.2471 0 9.40998 0 0 9.91616 10.0697 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5506 0 0 Q8NBA8 DTWD2_HUMAN tRNA-uridine aminocarboxypropyltransferase 2 (EC 2.5.1.25) (DTW domain-containing protein 2) DTWD2 Homo sapiens (Human) tRNA modification [GO:0006400] cytoplasm [GO:0005737]; nucleus [GO:0005634] tRNA-uridine aminocarboxypropyltransferase activity [GO:0016432] 0.95253 -1.4656 IGRRFSEER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.69957 0 0 0 0 0 0 10.4716 10.2334 0 0 0 Q8NBB2 STAS1_HUMAN Putative uncharacterized protein ST20-AS1 (ST20 antisense RNA 1) (ST20 antisense gene protein 1) ST20-AS1 C15orf37 Homo sapiens (Human) 0.87115 0.043286 VPAESGPGWLHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.85426 0 Q8NBE8 KLH23_HUMAN Kelch-like protein 23 KLHL23 Homo sapiens (Human) 0.90114 -0.69458 AMFTADMKEK 0 0 0 0 0 0 0 0 0 8.91639 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NBF2 NHLC2_HUMAN NHL repeat-containing protein 2 NHLRC2 Homo sapiens (Human) cytosol [GO:0005829]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093] 0.95795 -1.6734 IDLEAEK 0 9.66354 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1816 0 0 0 0 0 0 0 10.1935 Q8NBF6 AVL9_HUMAN Late secretory pathway protein AVL9 homolog AVL9 KIAA0241 Homo sapiens (Human) cell migration [GO:0016477] cytoplasm [GO:0005737]; membrane [GO:0016020]; recycling endosome [GO:0055037] 0.81675 0.22072 IGNVMVTTSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6526 Q8NBH2 KY_HUMAN Kyphoscoliosis peptidase (EC 3.4.-.-) KY Homo sapiens (Human) muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528]; proteolysis [GO:0006508] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; Z disc [GO:0030018] peptidase activity [GO:0008233] 0.95561 -1.6378 AIWIWICHHIEYDIAAAQEKDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2969 0 0 0 0 0 0 0 0 0 Q8NBI5 S43A3_HUMAN Equilibrative nucleobase transporter 1 (Protein FOAP-13) (Solute carrier family 43 member 3) SLC43A3 ENBT1 PSEC0252 Homo sapiens (Human) hypoxanthine transport [GO:0035344] basolateral plasma membrane [GO:0016323] adenine transmembrane transporter activity [GO:0015207]; fatty acid transmembrane transporter activity [GO:0015245]; guanine transmembrane transporter activity [GO:0015208]; xenobiotic transmembrane transporter activity [GO:0042910] 0.88207 -0.095769 QELRSFWSYAFSRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.7162 0 0 Q8NBI6 XXLT1_HUMAN "Xyloside xylosyltransferase 1 (EC 2.4.2.62) (UDP-xylose:alpha-xyloside alpha-1,3-xylosyltransferase)" XXYLT1 C3orf21 PSEC0251 Homo sapiens (Human) O-glycan processing [GO:0016266] endoplasmic reticulum membrane [GO:0005789] "magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; UDP-xylosyltransferase activity [GO:0035252]; xylosyl alpha-1,3-xylosyltransferase activity [GO:0140560]" 0.87054 0.054607 DHGYSDVFEAYFR 0 0 11.7407 11.4859 0 0 11.3477 0 0 0 0 0 0 0 0 10.428 10.0678 0 0 0 0 0 0 0 0 0 0 Q8NBJ4 GOLM1_HUMAN Golgi membrane protein 1 (Golgi membrane protein GP73) (Golgi phosphoprotein 2) GOLM1 C9orf155 GOLPH2 PSEC0242 UNQ686/PRO1326 Homo sapiens (Human) nucleus organization [GO:0006997]; regulation of lipid metabolic process [GO:0019216] endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886] 0.96236 -2.47 DTINLLDQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9417 10.7481 10.2396 10.4135 0 0 10.3612 0 0 Q8NBJ5 GT251_HUMAN Procollagen galactosyltransferase 1 (EC 2.4.1.50) (Collagen beta(1-O)galactosyltransferase 1) (ColGalT 1) (Glycosyltransferase 25 family member 1) (Hydroxylysine galactosyltransferase 1) COLGALT1 GLT25D1 PSEC0241 Homo sapiens (Human) collagen fibril organization [GO:0030199]; positive regulation of collagen fibril organization [GO:1904028] endoplasmic reticulum lumen [GO:0005788]; membrane [GO:0016020] procollagen galactosyltransferase activity [GO:0050211] 0.89703 -0.54596 AHSTLQDEAESFMHVQLEVMVK 0 0 0 12.9583 0 0 0 12.5639 0 0 0 9.12252 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4752 Q8NBL1 PGLT1_HUMAN Protein O-glucosyltransferase 1 (EC 2.4.1.376) (CAP10-like 46 kDa protein) (hCLP46) (KTEL motif-containing protein 1) (Myelodysplastic syndromes relative protein) (O-glucosyltransferase Rumi homolog) (hRumi) (Protein O-xylosyltransferase POGLUT1) (EC 2.4.2.63) POGLUT1 C3orf9 CLP46 KTELC1 MDSRP MDS010 UNQ490/PRO1006 Homo sapiens (Human) axial mesoderm development [GO:0048318]; circulatory system development [GO:0072359]; gastrulation [GO:0007369]; muscle tissue development [GO:0060537]; paraxial mesoderm development [GO:0048339]; positive regulation of Notch signaling pathway [GO:0045747]; protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via serine [GO:0018242]; regulation of gastrulation [GO:0010470]; somitogenesis [GO:0001756] endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788] EGF-domain serine glucosyltransferase activity [GO:0140561]; EGF-domain serine xylosyltransferase activity [GO:0140562]; glucosyltransferase activity [GO:0046527]; UDP-glucosyltransferase activity [GO:0035251]; UDP-xylosyltransferase activity [GO:0035252] 0.96744 -3.7031 GVAASFR 0 0 0 0 0 0 0 0 0 11.5348 0 0 0 9.52677 0 0 0 0 0 0 0 0 0 0 0 9.40352 0 Q8NBM8 PCYXL_HUMAN Prenylcysteine oxidase-like (EC 1.8.3.-) PCYOX1L PSEC0105 Homo sapiens (Human) prenylated protein catabolic process [GO:0030327]; prenylcysteine catabolic process [GO:0030328] extracellular region [GO:0005576]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093] prenylcysteine oxidase activity [GO:0001735] 0.7885 0.24743 QPQEAAVWR 0 0 0 0 0 0 0 0 0 8.57122 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NBN3 TM87A_HUMAN Transmembrane protein 87A TMEM87A PSEC0094 Homo sapiens (Human) "retrograde transport, endosome to Golgi [GO:0042147]" cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139] 0.96193 -2.0465 AVFYAEFQNIRYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.06385 0 0 9.67559 10.0239 0 0 0 0 Q8NBN7 RDH13_HUMAN Retinol dehydrogenase 13 (EC 1.1.1.300) (Short chain dehydrogenase/reductase family 7C member 3) RDH13 SDR7C3 PSEC0082 UNQ736/PRO1430 Homo sapiens (Human) eye photoreceptor cell development [GO:0042462]; response to high light intensity [GO:0009644]; retina layer formation [GO:0010842]; retinal metabolic process [GO:0042574] mitochondrial inner membrane [GO:0005743] NADP-retinol dehydrogenase activity [GO:0052650] 0.85327 0.10602 DIRGETLNHHVNAR 10.4832 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NBP0 TTC13_HUMAN Tetratricopeptide repeat protein 13 (TPR repeat protein 13) TTC13 PSEC0076 Homo sapiens (Human) 0.22845 0.86561 INEAVNDLTK 0 0 0 0 0 0 0 9.36982 9.31719 0 0 0 0 0 0 0 0 0 9.04669 0 0 0 0 9.80761 0 0 0 Q8NBP7 PCSK9_HUMAN Proprotein convertase subtilisin/kexin type 9 (EC 3.4.21.-) (Neural apoptosis-regulated convertase 1) (NARC-1) (Proprotein convertase 9) (PC9) (Subtilisin/kexin-like protease PC9) PCSK9 NARC1 PSEC0052 Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to insulin stimulus [GO:0032869]; cellular response to starvation [GO:0009267]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; kidney development [GO:0001822]; lipoprotein metabolic process [GO:0042157]; liver development [GO:0001889]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; lysosomal transport [GO:0007041]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of low-density lipoprotein particle receptor binding [GO:1905596]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of receptor internalization [GO:0002091]; negative regulation of receptor recycling [GO:0001920]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; phospholipid metabolic process [GO:0006644]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of receptor internalization [GO:0002092]; protein autoprocessing [GO:0016540]; regulation of neuron apoptotic process [GO:0043523]; regulation of signaling receptor activity [GO:0010469]; triglyceride metabolic process [GO:0006641] cell surface [GO:0009986]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; endolysosome membrane [GO:0036020]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; PCSK9-AnxA2 complex [GO:1990667]; PCSK9-LDLR complex [GO:1990666]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791] apolipoprotein binding [GO:0034185]; apolipoprotein receptor binding [GO:0034190]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; protein self-association [GO:0043621]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; signaling receptor inhibitor activity [GO:0030547]; sodium channel inhibitor activity [GO:0019871]; very-low-density lipoprotein particle binding [GO:0034189]; very-low-density lipoprotein particle receptor binding [GO:0070326] 0.96764 -3.7084 ITPPRYR 0 9.59214 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NBS9 TXND5_HUMAN Thioredoxin domain-containing protein 5 (EC 1.8.4.-) (EC 5.3.4.1) (Endoplasmic reticulum resident protein 46) (ER protein 46) (ERp46) (Thioredoxin-like protein p46) TXNDC5 TLP46 UNQ364/PRO700 Homo sapiens (Human) negative regulation of apoptotic process [GO:0043066]; protein folding [GO:0006457] azurophil granule lumen [GO:0035578]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202] protein disulfide isomerase activity [GO:0003756]; protein-disulfide reductase activity [GO:0015035] 0 4.1037 EFPGLAGVK 0 0 0 0 0 0 8.72795 0 0 0 0 0 0 10.2885 10.7399 0 0 10.9076 0 9.86836 0 10.1043 11.6857 10.2334 10.5393 11.2659 10.8826 Q8NBV8 SYT8_HUMAN Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII) SYT8 Homo sapiens (Human) calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cellular response to calcium ion [GO:0071277]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; synaptic vesicle endocytosis [GO:0048488] acrosomal vesicle [GO:0001669]; axon [GO:0030424]; dense core granule [GO:0031045]; plasma membrane [GO:0005886]; synaptic vesicle membrane [GO:0030672] calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; clathrin binding [GO:0030276]; phosphatidylserine binding [GO:0001786]; syntaxin binding [GO:0019905] 0.78591 0.25532 VSVSTQAGHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.3869 0 0 0 0 0 0 0 0 0 Q8NBW4 S38A9_HUMAN Neutral amino acid transporter 9 (Solute carrier family 38 member 9) (Up-regulated in lung cancer 11) SLC38A9 URLC11 Homo sapiens (Human) amino acid transmembrane transport [GO:0003333]; asparagine transport [GO:0006867]; cellular response to amino acid stimulus [GO:0071230]; glutamine transport [GO:0006868]; L-arginine transmembrane transport [GO:1903826]; positive regulation of TOR signaling [GO:0032008]; positive regulation of TORC1 signaling [GO:1904263] late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764] amino acid transmembrane transporter activity [GO:0015171]; arginine binding [GO:0034618]; cholesterol binding [GO:0015485]; guanyl-nucleotide exchange factor activity [GO:0005085]; L-amino acid transmembrane transporter activity [GO:0015179]; L-arginine transmembrane transporter activity [GO:0061459]; L-asparagine transmembrane transporter activity [GO:0015182]; L-glutamine transmembrane transporter activity [GO:0015186]; L-leucine transmembrane transporter activity [GO:0015190]; metal ion binding [GO:0046872]; sterol sensor activity [GO:0032935] 0.9324 -1.2679 NNKKQENNVR 0 0 0 0 0 0 0 0 0 0 0 0 10.313 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NBX0 SCPDL_HUMAN Saccharopine dehydrogenase-like oxidoreductase (EC 1.-.-.-) SCCPDH CGI-49 Homo sapiens (Human) glycolipid biosynthetic process [GO:0009247] extracellular region [GO:0005576]; lipid droplet [GO:0005811]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093] oxidoreductase activity [GO:0016491] 0.80829 0.22812 SAIYGFGDQSNLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4466 10.0013 0 0 0 Q8NBZ7 UXS1_HUMAN UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UGD) (UXS-1) (hUXS) (hUXS1) UXS1 UNQ2538/PRO6079 Homo sapiens (Human) D-xylose metabolic process [GO:0042732]; UDP-D-xylose biosynthetic process [GO:0033320] catalytic complex [GO:1902494]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; Golgi cisterna membrane [GO:0032580] identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; protein homodimerization activity [GO:0042803]; UDP-glucuronate decarboxylase activity [GO:0048040] 0.92279 -1.0576 IFNTFGPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.38616 0 0 0 0 0 0 0 0 0 Q8NC26 ZN114_HUMAN Zinc finger protein 114 ZNF114 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] extracellular exosome [GO:0070062]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.90126 -0.69666 EDGSLRAHNTHGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0046 0 0 0 0 0 0 0 0 0 0 0 0 Q8NC56 LEMD2_HUMAN LEM domain-containing protein 2 (hLEM2) LEMD2 Homo sapiens (Human) heart formation [GO:0060914]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase B signaling [GO:0051898]; neurogenesis [GO:0022008]; nuclear envelope organization [GO:0006998]; protein localization to chromatin [GO:0071168]; skeletal muscle cell differentiation [GO:0035914] cytoplasm [GO:0005737]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; spindle [GO:0005819] 0.95637 -1.591 ATRAGPAGAARARPEVGR 12.962 0 9.32308 0 0 0 0 0 0 10.2825 10.1072 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NC74 RB8NL_HUMAN RBBP8 N-terminal-like protein RBBP8NL C20orf151 Homo sapiens (Human) extracellular space [GO:0005615] 0.43333 0.65374 EVLGLQNK 0 0 0 0 0 0 0 11.9253 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.82799 0 0 0 Q8NCD3 HJURP_HUMAN Holliday junction recognition protein (14-3-3-associated AKT substrate) (Fetal liver-expressing gene 1 protein) (Up-regulated in lung cancer 9) HJURP FAKTS FLEG1 URLC9 Homo sapiens (Human) CENP-A containing chromatin assembly [GO:0034080]; chromosome segregation [GO:0007059]; regulation of DNA binding [GO:0051101]; regulation of protein-containing complex assembly [GO:0043254] "chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; kinetochore [GO:0000776]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]" DNA binding [GO:0003677]; histone binding [GO:0042393]; identical protein binding [GO:0042802] 0.96117 -2.0013 EVPGHGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6421 0 0 9.02956 0 0 0 0 0 0 0 0 0 Q8NCE2 MTMRE_HUMAN Myotubularin-related protein 14 (EC 3.1.3.-) (HCV NS5A-transactivated protein 4 splice variant A-binding protein 1) (NS5ATP4ABP1) (hJumpy) MTMR14 C3orf29 Homo sapiens (Human) dephosphorylation [GO:0016311]; macroautophagy [GO:0016236]; phosphatidylinositol biosynthetic process [GO:0006661] cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726] "phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity [GO:0052629]; phosphatidylinositol-3-phosphate phosphatase activity [GO:0004438]; protein serine/threonine phosphatase activity [GO:0004722]" 0.59152 0.44827 SISSNAL 8.37617 11.7998 0 0 0 0 12.1534 8.5969 0 12.4237 0 0 8.52454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NCF0 CL18C_HUMAN C-type lectin domain family 18 member C (Mannose receptor-like protein 3) CLEC18C MRLP3 Homo sapiens (Human) endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794] polysaccharide binding [GO:0030247] 0.84939 0.15817 YICQFAQEHISR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.37888 0 Q8NCG5 CHST4_HUMAN Carbohydrate sulfotransferase 4 (EC 2.8.2.-) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 3) (GST-3) (High endothelial cells N-acetylglucosamine 6-O-sulfotransferase) (HEC-GlcNAc6ST) (L-selectin ligand sulfotransferase) (LSST) (N-acetylglucosamine 6-O-sulfotransferase 2) (GlcNAc6ST-2) (Gn6st-2) CHST4 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; immune response [GO:0006955]; inflammatory response [GO:0006954]; N-acetylglucosamine metabolic process [GO:0006044]; O-glycan processing [GO:0016266]; positive regulation of leukocyte tethering or rolling [GO:1903238]; protein sulfation [GO:0006477]; sulfur compound metabolic process [GO:0006790] Golgi membrane [GO:0000139]; trans-Golgi network [GO:0005802] N-acetylglucosamine 6-O-sulfotransferase activity [GO:0001517]; sulfotransferase activity [GO:0008146] 0.47972 0.62383 IVMGQHEQK 0 0 0 0 0 0 0 10.2662 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NCG7 DGLB_HUMAN Diacylglycerol lipase-beta (DAGL-beta) (DGL-beta) (EC 3.1.1.116) (KCCR13L) (PUFA-specific triacylglycerol lipase) (EC 3.1.1.3) (Sn1-specific diacylglycerol lipase beta) DAGLB Homo sapiens (Human) arachidonic acid metabolic process [GO:0019369]; diacylglycerol catabolic process [GO:0046340]; neuroblast proliferation [GO:0007405]; neurogenesis [GO:0022008]; neurotransmitter biosynthetic process [GO:0042136]; positive regulation of triglyceride catabolic process [GO:0010898]; prostaglandin biosynthetic process [GO:0001516]; regulation of inflammatory response [GO:0050727] lysosomal membrane [GO:0005765]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] acylglycerol lipase activity [GO:0047372]; lipase activity [GO:0016298]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806] 0.75848 0.30181 IIHLQEEGASGR 0 0 0 0 0 0 8.64962 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NCH0 CHSTE_HUMAN Carbohydrate sulfotransferase 14 (EC 2.8.2.35) (Dermatan 4-sulfotransferase 1) (D4ST-1) (hD4ST1) CHST14 D4ST1 UNQ1925/PRO4400 Homo sapiens (Human) dermatan sulfate biosynthetic process [GO:0030208]; dermatan sulfate proteoglycan metabolic process [GO:0050655] extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; membrane [GO:0016020] N-acetylgalactosamine 4-O-sulfotransferase activity [GO:0001537]; phosphate ion binding [GO:0042301]; sulfotransferase activity [GO:0008146] 0.95486 -1.6133 ALRRAPLGR 0 0 0 0 0 10.3651 0 0 0 0 0 0 0 0 0 0 12.7609 0 0 0 0 0 0 0 0 0 0 Q8NCI6 GLBL3_HUMAN Beta-galactosidase-1-like protein 3 (EC 3.2.1.-) GLB1L3 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975] lysosome [GO:0005764]; vacuole [GO:0005773] beta-galactosidase activity [GO:0004565] 0.95491 -1.5624 WGDKHHVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.33644 0 0 Q8NCJ5 SPRY3_HUMAN SPRY domain-containing protein 3 SPRYD3 Homo sapiens (Human) 0.93217 -1.2867 GSVAYHADDGK 0 0 0 0 0 0 0 0 9.17607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NCK3 ZN485_HUMAN Zinc finger protein 485 ZNF485 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.90589 -0.72821 IEWRHLDAAQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4841 0 0 0 0 0 0 0 0 Q8NCL4 GALT6_HUMAN Polypeptide N-acetylgalactosaminyltransferase 6 (EC 2.4.1.41) (Polypeptide GalNAc transferase 6) (GalNAc-T6) (pp-GaNTase 6) (Protein-UDP acetylgalactosaminyltransferase 6) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 6) GALNT6 Homo sapiens (Human) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via threonine [GO:0018243] Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; perinuclear region of cytoplasm [GO:0048471] carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; polypeptide N-acetylgalactosaminyltransferase activity [GO:0004653] 0.72951 0.33259 LAEVWMDSYK 0 0 0 0 0 9.0766 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.58772 0 9.82283 Q8NCL8 TM116_HUMAN Transmembrane protein 116 TMEM116 Homo sapiens (Human) membrane [GO:0016020] 0.7715 0.27022 LTKPQDTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.56255 0 0 0 0 0 0 0 0 0 0 0 0 Q8NCM2 KCNH5_HUMAN Potassium voltage-gated channel subfamily H member 5 (Ether-a-go-go potassium channel 2) (hEAG2) (Voltage-gated potassium channel subunit Kv10.2) KCNH5 EAG2 Homo sapiens (Human) potassium ion transmembrane transport [GO:0071805]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of membrane potential [GO:0042391]; regulation of monoatomic ion transmembrane transport [GO:0034765] cell surface [GO:0009986]; plasma membrane [GO:0005886] calmodulin binding [GO:0005516]; protein-containing complex binding [GO:0044877]; transmembrane transporter binding [GO:0044325]; voltage-gated potassium channel activity [GO:0005249] 0.83621 0.18922 ADICVHLNR 0 9.25515 9.17752 0 9.58778 0 0 0 0 0 0 0 7.8835 0 0 0 0 0 0 0 0 0 0 0 0 11.0429 8.71648 Q8NCM8 DYHC2_HUMAN Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein 2 heavy chain) (Dynein cytoplasmic heavy chain 2) (Dynein heavy chain 11) (hDHC11) (Dynein heavy chain isotype 1B) DYNC2H1 DHC1B DHC2 DNCH2 DYH1B KIAA1997 Homo sapiens (Human) coronary vasculature development [GO:0060976]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic limb morphogenesis [GO:0030326]; forebrain development [GO:0030900]; Golgi organization [GO:0007030]; intraciliary retrograde transport [GO:0035721]; kidney development [GO:0001822]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization to cilium [GO:0061512]; protein processing [GO:0016485]; spinal cord motor neuron differentiation [GO:0021522] apical part of cell [GO:0045177]; axoneme [GO:0005930]; ciliary tip [GO:0097542]; cilium [GO:0005929]; cytoplasmic dynein complex [GO:0005868]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; microtubule [GO:0005874]; motile cilium [GO:0031514]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; cytoskeletal motor activity [GO:0003774]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; minus-end-directed microtubule motor activity [GO:0008569] 0.96816 -8.8757 DIVNQVGDNR 0 0 0 0 0 0 0 8.84266 11.7379 0 0 0 0 0 8.52097 0 0 10.2564 10.2016 0 0 0 0 9.57801 11.1513 0 11.3941 Q8NCN2 ZBT34_HUMAN Zinc finger and BTB domain-containing protein 34 ZBTB34 KIAA1993 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of cytokine production [GO:0001817]; regulation of immune system process [GO:0002682] chromatin [GO:0000785]; nucleoplasm [GO:0005654] "DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]" 0.95159 -1.4292 SARGHWYPYNERLICIYCGK 0 0 0 0 0 0 0 14.0458 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NCN4 RN169_HUMAN E3 ubiquitin-protein ligase RNF169 (EC 2.3.2.27) (RING finger protein 169) (RING-type E3 ubiquitin transferase RNF169) RNF169 KIAA1991 Homo sapiens (Human) DNA damage response [GO:0006974]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of double-strand break repair [GO:2000780]; protein ubiquitination [GO:0016567] cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861] K63-linked polyubiquitin modification-dependent protein binding [GO:0070530]; metal ion binding [GO:0046872]; nucleosome binding [GO:0031491]; ubiquitin modification-dependent histone binding [GO:0061649]; ubiquitin-protein transferase activity [GO:0004842] 0.96993 -3.2711 LDKTCISRAMK 0 0 0 0 0 0 0 0 0 0 9.44363 0 9.96513 0 10.1839 0 0 0 0 0 0 0 0 0 0 0 0 Q8NCQ5 FBX15_HUMAN F-box only protein 15 FBXO15 FBX15 Homo sapiens (Human) cytosol [GO:0005829]; SCF ubiquitin ligase complex [GO:0019005] 0.9545 -1.5015 EYITKQIASVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7908 0 0 0 0 0 0 0 0 0 Q8NCQ7 PRCA1_HUMAN Protein PROCA1 (Protein interacting with cyclin A1) PROCA1 Homo sapiens (Human) arachidonic acid secretion [GO:0050482]; phospholipid metabolic process [GO:0006644] cyclin binding [GO:0030332]; phospholipase A2 activity [GO:0004623] 0.84465 0.15266 TTLTIER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.91355 0 0 0 0 Q8NCR3 MFI_HUMAN Protein MFI (Mitochondrial fission factor interactor) MFI C11orf65 Homo sapiens (Human) negative regulation of mitochondrial fission [GO:0090258]; negative regulation of protein targeting to mitochondrion [GO:1903215] cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741] 0.84913 0.11959 IFTHRPIEDLCANSPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.80436 0 Q8NCS7 CTL5_HUMAN Choline transporter-like protein 5 (Solute carrier family 44 member 5) SLC44A5 CTL5 Homo sapiens (Human) choline transport [GO:0015871]; phosphatidylcholine biosynthetic process [GO:0006656]; transmembrane transport [GO:0055085] membrane [GO:0016020]; plasma membrane [GO:0005886] choline transmembrane transporter activity [GO:0015220]; transmembrane transporter activity [GO:0022857] 0.96965 -4.0417 DKSYWEDYR 8.52199 0 0 0 0 0 0 0 0 0 8.93767 0 0 0 0 0 0 0 0 0 0 0 0 9.86569 0 0 0 Q8NCT3 MACA2_HUMAN Putative tyrosine carboxypeptidase MATCAP2 (EC 3.4.17.-) MATCAP2 KIAA0895 Homo sapiens (Human) proteolysis [GO:0006508] carboxypeptidase activity [GO:0004180]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237] 0.92206 -1.1283 KDPFLWR 0 0 0 0 0 0 0 0 10.3009 0 0 0 0 10.0393 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NCU1 CC197_HUMAN Uncharacterized protein CCDC197 (Coiled-coil domain-containing protein 197) CCDC197 C14orf48 LINC00521 Homo sapiens (Human) 0.57578 0.47605 HKLFEDYLIK 17.7903 17.7538 17.5165 14.4262 14.777 14.6076 16.6737 17.1118 10.8517 16.8849 17.168 16.9184 15.3775 15.3156 15.4214 16.3121 16.6814 16.4619 12.6793 12.4611 12.5508 11.8445 11.7495 11.7964 12.9409 0 12.9904 Q8NCU4 CC191_HUMAN Coiled-coil domain-containing protein 191 CCDC191 KIAA1407 Homo sapiens (Human) phosphatase binding [GO:0019902] 0.96378 -2.11 AQEEERQKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2166 0 Q8NCU7 C2C4A_HUMAN C2 calcium-dependent domain-containing protein 4A (Nuclear-localized factor 1) (Protein FAM148A) C2CD4A FAM148A NLF1 Homo sapiens (Human) positive regulation of acute inflammatory response [GO:0002675]; regulation of cell adhesion [GO:0030155]; regulation of vascular permeability involved in acute inflammatory response [GO:0002528] nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.9518 -1.4285 IPEFCIPPRLMPRLALAALR 0 0 9.23105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NCW5 NNRE_HUMAN NAD(P)H-hydrate epimerase (EC 5.1.99.6) (Apolipoprotein A-I-binding protein) (AI-BP) (NAD(P)HX epimerase) (YjeF N-terminal domain-containing protein 1) (YjeF_N1) NAXE AIBP APOA1BP YJEFN1 Homo sapiens (Human) lipid transport [GO:0006869]; membrane raft distribution [GO:0031580]; negative regulation of angiogenesis [GO:0016525]; nicotinamide nucleotide metabolic process [GO:0046496]; regulation of cholesterol efflux [GO:0010874]; sprouting angiogenesis [GO:0002040] cell body [GO:0044297]; cilium [GO:0005929]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759] identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NADHX epimerase activity [GO:0052856]; NADPHX epimerase activity [GO:0052857]; nucleotide binding [GO:0000166] 0.91566 -0.8061 KSATQFTGR 0 0 0 0 0 0 0 10.3866 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NCX0 CC150_HUMAN Coiled-coil domain-containing protein 150 CCDC150 Homo sapiens (Human) 0.94082 -1.3276 ELERQNLETFK 10.7207 10.6306 0 10.3144 10.2186 10.3796 0 0 0 11.8816 10.8349 0 10.6139 10.5641 10.5632 10.6372 10.4325 10.4121 0 0 0 0 0 0 9.95548 10.4575 9.32834 Q8NCY6 MSD4_HUMAN Myb/SANT-like DNA-binding domain-containing protein 4 (Myb/SANT-like DNA-binding domain containing 4 with coiled-coils) MSANTD4 KIAA1826 DC25 Homo sapiens (Human) nucleus [GO:0005634] 0.91376 -0.82102 RLDIEAER 0 0 0 0 0 0 9.35295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8ND04 SMG8_HUMAN Nonsense-mediated mRNA decay factor SMG8 (Amplified in breast cancer gene 2 protein) (Protein smg-8 homolog) SMG8 ABC2 C17orf71 Homo sapiens (Human) "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of protein kinase activity [GO:0045859]" cytosol [GO:0005829] 0.96924 -4.5163 AFVGFEYEDSRGR 0 0 16.9887 9.59872 0 0 0 11.1378 0 0 0 0 0 0 0 16.9372 0 0 0 0 0 0 0 0 0 0 0 Q8ND07 BBOF1_HUMAN Basal body-orientation factor 1 (Coiled-coil domain-containing protein 176) BBOF1 C14orf45 CCDC176 Homo sapiens (Human) motile cilium assembly [GO:0044458] ciliary basal body [GO:0036064]; cytoplasm [GO:0005737] 0.96747 -2.8106 EKAQEEKDK 0 0 0 0 0 0 0 0 0 0 0 9.3807 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0385 0 Q8ND23 CARL3_HUMAN "Capping protein, Arp2/3 and myosin-I linker protein 3 (Capping protein regulator and myosin 1 linker protein 3) (Leucine-rich repeat-containing protein 16B)" CARMIL3 C14orf121 LRRC16B Homo sapiens (Human) cell migration [GO:0016477]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315] cytoplasm [GO:0005737]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886] 0.010025 1.8794 ALQINSSLR 0 0 0 0 9.44555 0 0 0 0 0 0 0 9.91751 10.1896 0 0 0 0 0 0 10.1236 0 0 0 10.3874 0 8.82126 Q8ND24 RN214_HUMAN RING finger protein 214 RNF214 Homo sapiens (Human) metal ion binding [GO:0046872]; ubiquitin-protein transferase activity [GO:0004842] 0.9239 -1.0447 AGCHTKQLASR 0 0 0 0 0 0 0 0 0 9.33069 0 0 0 0 10.5811 0 0 0 0 0 0 0 0 0 0 0 0 Q8ND25 ZNRF1_HUMAN E3 ubiquitin-protein ligase ZNRF1 (EC 2.3.2.27) (Nerve injury-induced gene 283 protein) (RING-type E3 ubiquitin transferase ZNRF1) (Zinc/RING finger protein 1) ZNRF1 NIN283 Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; membrane [GO:0016020]; synaptic vesicle membrane [GO:0030672] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.55475 0.55736 LPCLCIYHK 0 0 0 9.52337 0 9.8507 10.6468 0 0 0 0 0 9.86292 0 0 0 0 0 0 0 9.25538 0 0 0 0 0 0 Q8ND30 LIPB2_HUMAN Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) PPFIBP2 Homo sapiens (Human) neuromuscular junction development [GO:0007528] cytosol [GO:0005829]; extracellular space [GO:0005615]; presynaptic active zone [GO:0048786] identical protein binding [GO:0042802] 0.91773 -0.8564 EIVMVTQGPSER 0 0 0 0 0 0 0 0 0 0 0 0 9.18723 0 0 9.17323 0 0 0 0 0 0 0 0 0 0 0 Q8ND56 LS14A_HUMAN Protein LSM14 homolog A (Protein FAM61A) (Protein SCD6 homolog) (Putative alpha-synuclein-binding protein) (AlphaSNBP) (RNA-associated protein 55A) (hRAP55) (hRAP55A) LSM14A C19orf13 FAM61A RAP55 RAP55A Homo sapiens (Human) defense response to virus [GO:0051607]; mitotic spindle assembly [GO:0090307]; negative regulation of translation [GO:0017148]; P-body assembly [GO:0033962]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; RIG-I signaling pathway [GO:0039529]; stress granule assembly [GO:0034063] cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; mitotic spindle [GO:0072686]; P-body [GO:0000932]; ribonucleoprotein complex [GO:1990904] double-stranded DNA binding [GO:0003690]; double-stranded RNA binding [GO:0003725]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727] 0.88414 -0.29854 ERRPTWAEER 0 0 0 0 0 0 0 9.03425 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8ND61 CC020_HUMAN Uncharacterized protein C3orf20 C3orf20 Homo sapiens (Human) cytoplasm [GO:0005737]; membrane [GO:0016020] 0.84979 0.11621 VLNGYGLSKQNLLK 9.27191 9.51124 9.17038 0 0 8.93074 0 9.57722 9.40523 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8ND71 GIMA8_HUMAN GTPase IMAP family member 8 (Immune-associated nucleotide-binding protein 9) (IAN-9) (Protein IanT) GIMAP8 IAN9 IANT Homo sapiens (Human) regulation of T cell apoptotic process [GO:0070232] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrion [GO:0005739] GTP binding [GO:0005525] 0.87045 0.047824 DEQITQVLELLRK 0 0 13.1443 0 0 0 9.55221 0 0 0 0 0 0 0 0 0 0 0 0 0 9.15768 0 0 0 0 0 0 Q8ND82 Z280C_HUMAN Zinc finger protein 280C (Suppressor of hairy wing homolog 3) (Zinc finger protein 633) ZNF280C SUHW3 ZNF633 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.8821 -0.30979 CNVQFNLLDPLK 0 0 9.66238 8.27095 0 0 0 0 0 0 0 0 0 11.5404 0 0 0 0 9.93006 0 11.1676 0 0 0 0 0 0 Q8ND90 PNMA1_HUMAN Paraneoplastic antigen Ma1 (37 kDa neuronal protein) (Neuron- and testis-specific protein 1) PNMA1 MA1 Homo sapiens (Human) inflammatory response to antigenic stimulus [GO:0002437]; positive regulation of apoptotic process [GO:0043065] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] 0.84781 0.12811 LHLFLAR 10.1586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NDA2 HMCN2_HUMAN Hemicentin-2 HMCN2 Homo sapiens (Human) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; synapse organization [GO:0050808] axon [GO:0030424]; cleavage furrow [GO:0032154]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886] axon guidance receptor activity [GO:0008046]; calcium ion binding [GO:0005509] 0.96007 -1.9017 AGAQLGAR 0 12.1792 12.8344 0 9.20528 9.39184 0 0 0 0 0 0 0 0 0 0 0 9.04486 0 0 0 0 9.35421 0 0 0 0 Q8NDB6 FA156_HUMAN Protein FAM156A/FAM156B (Transmembrane protein 29/29B) FAM156A TMEM29 PP12994 PRO0659; FAM156B TMEM29B Homo sapiens (Human) membrane [GO:0016020]; nuclear envelope [GO:0005635] methylated histone binding [GO:0035064] 0.65161 0.39562 NPASPSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.05675 0 0 0 0 0 0 0 0 0 Q8NDD1 CA131_HUMAN Uncharacterized protein C1orf131 C1orf131 cPERP-A Homo sapiens (Human) ribosomal small subunit biogenesis [GO:0042274] chromosome [GO:0005694]; nucleolus [GO:0005730]; small-subunit processome [GO:0032040] RNA binding [GO:0003723] 0.70214 0.37203 HCAPSGTPTGPEILAAAVPPSSLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6968 0 0 Q8NDF8 PAPD5_HUMAN Terminal nucleotidyltransferase 4B (Non-canonical poly(A) RNA polymerase PAPD5) (EC 2.7.7.19) (PAP-associated domain-containing protein 5) (Terminal guanylyltransferase) (EC 2.7.7.-) (Terminal uridylyltransferase 3) (TUTase 3) (Topoisomerase-related function protein 4-2) (TRF4-2) TENT4B GLD4 PAPD5 TRF4-2 TUT3 Homo sapiens (Human) carbohydrate homeostasis [GO:0033500]; cell cycle [GO:0007049]; cell division [GO:0051301]; histone mRNA catabolic process [GO:0071044]; miRNA catabolic process [GO:0010587]; mRNA polyadenylation [GO:0006378]; ncRNA polyadenylation [GO:0043629]; ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process [GO:0043630]; negative regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060212]; negative regulation of telomere maintenance via telomerase [GO:0032211]; positive regulation of 3'-UTR-mediated mRNA stabilization [GO:1905870]; RNA 3' uridylation [GO:0071076]; RNA 3'-end processing [GO:0031123]; rRNA processing [GO:0006364]; sno(s)RNA polyadenylation [GO:0071050] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; TRAMP complex [GO:0031499] DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; guanylyltransferase activity [GO:0070568]; metal ion binding [GO:0046872]; poly(A) RNA polymerase activity [GO:1990817]; RNA binding [GO:0003723]; telomerase RNA binding [GO:0070034] 0.95848 -1.6787 MRMEVVNR 0 9.13052 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NDG6 TDRD9_HUMAN ATP-dependent RNA helicase TDRD9 (EC 3.6.4.13) (Tudor domain-containing protein 9) TDRD9 C14orf75 Homo sapiens (Human) cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; fertilization [GO:0009566]; male meiosis I [GO:0007141]; male meiotic nuclear division [GO:0007140]; negative regulation of transposition [GO:0010529]; piRNA processing [GO:0034587]; retrotransposon silencing [GO:0010526]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; nucleus [GO:0005634]; piP-body [GO:0071547] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; helicase activity [GO:0004386]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.96965 -4.4156 ACRQTGELR 0 0 0 9.71339 0 0 0 8.20433 0 0 8.50152 0 0 0 0 0 9.04245 0 0 0 0 0 0 0 9.63748 0 0 Q8NDH2 CC168_HUMAN Leucine-rich repeat transmembrane protein CCDC168 (Coiled-coil domain-containing protein 168) CCDC168 C13orf40 Homo sapiens (Human) membrane [GO:0016020] 0.96826 -9.2391 AEALPLALLCNGK 0 0 15.0923 0 0 9.69352 9.58534 0 11.9657 10.7056 11.9064 10.3355 0 0 10.3412 11.0591 0 0 10.1657 10.6822 9.24015 0 0 0 0 8.53664 11.0647 Q8NDH6 ICA1L_HUMAN Islet cell autoantigen 1-like protein (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 14 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 15 protein) ICA1L ALS2CR14 ALS2CR15 Homo sapiens (Human) regulation of transport [GO:0051049] Golgi apparatus [GO:0005794] protein domain specific binding [GO:0019904] 0.73761 0.32466 DVSQELDPDTLK 0 10.1491 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NDI1 EHBP1_HUMAN EH domain-binding protein 1 EHBP1 KIAA0903 NACSIN Homo sapiens (Human) endocytosis [GO:0006897]; protein transport [GO:0015031] cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] 0.96818 -2.7612 KPNASQSLLVWCKEVTKNYR 0 10.0751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8991 0 0 Q8NDM7 CFA43_HUMAN Cilia- and flagella-associated protein 43 (WD repeat-containing protein 96) CFAP43 C10orf79 WDR96 Homo sapiens (Human) brain development [GO:0007420]; cerebrospinal fluid circulation [GO:0090660]; cilium assembly [GO:0060271]; establishment of localization in cell [GO:0051649]; mucociliary clearance [GO:0120197]; regulation of cilium beat frequency [GO:0003356]; sperm axoneme assembly [GO:0007288] 9+2 motile cilium [GO:0097729]; axoneme [GO:0005930]; extracellular region [GO:0005576] 0.9697 -3.168 EDLNQKAWDIQMLFFSR 0 0 0 0 0 0 0 9.58524 0 0 0 0 0 0 0 0 0 0 0 8.66092 0 0 0 0 0 0 0 Q8NDN9 RCBT1_HUMAN RCC1 and BTB domain-containing protein 1 (Chronic lymphocytic leukemia deletion region gene 7 protein) (CLL deletion region gene 7 protein) (Regulator of chromosome condensation and BTB domain-containing protein 1) RCBTB1 CLLD7 E4.5 Homo sapiens (Human) cell cycle [GO:0007049]; chromatin organization [GO:0006325] cytoplasm [GO:0005737]; nucleus [GO:0005634] 0.95402 -1.5259 YIHVHKAVLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2003 Q8NDP4 ZN439_HUMAN Zinc finger protein 439 ZNF439 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.96282 -2.6659 AFMCPRYVRR 9.89207 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.75452 0 0 0 0 Q8NDQ6 ZN540_HUMAN Zinc finger protein 540 ZNF540 Nbla10512 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of translation [GO:0017148] cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] metal ion binding [GO:0046872]; mRNA regulatory element binding translation repressor activity [GO:0000900]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96946 -3.1289 AFSVCGQLTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.63626 9.43062 0 0 8.37008 0 0 Q8NDT2 RB15B_HUMAN Putative RNA-binding protein 15B (One-twenty two protein 3) (HsOTT3) (HuOTT3) (RNA-binding motif protein 15B) RBM15B OTT3 Homo sapiens (Human) "dosage compensation by inactivation of X chromosome [GO:0009048]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA methylation [GO:0001510]; RNA splicing [GO:0008380]" nuclear envelope [GO:0005635]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA N6-methyladenosine methyltransferase complex [GO:0036396] mRNA binding [GO:0003729]; RNA binding [GO:0003723] 0.96944 -4.0052 DSERNHR 0 10.6383 9.61462 0 0 0 0 0 0 0 0 9.931 0 0 0 0 0 0 0 0 9.55044 0 10.1329 0 0 0 0 Q8NDV3 SMC1B_HUMAN Structural maintenance of chromosomes protein 1B (SMC protein 1B) (SMC-1-beta) (SMC-1B) SMC1B SMC1L2 Homo sapiens (Human) meiotic cell cycle [GO:0051321]; sister chromatid cohesion [GO:0007062] "chromosome, centromeric region [GO:0000775]; cohesin complex [GO:0008278]; cytosol [GO:0005829]; lateral element [GO:0000800]; meiotic cohesin complex [GO:0030893]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]" ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA binding [GO:0003677] 0.95522 -1.604 ELKEQVR 0 0 0 0 0 0 0 0 0 11.8239 0 12.0281 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.54759 Q8NDV7 TNR6A_HUMAN Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (EMSY interactor protein) (GW182 autoantigen) (Protein GW1) (Glycine-tryptophan protein of 182 kDa) TNRC6A CAGH26 KIAA1460 TNRC6 Homo sapiens (Human) cellular response to starvation [GO:0009267]; endoderm development [GO:0007492]; miRNA-mediated gene silencing [GO:0035195]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213] cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; RISC complex [GO:0016442] RNA binding [GO:0003723] 0.9676 -3.7001 EVDHLRDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.9497 0 0 0 0 0 0 0 Q8NDW4 ZN248_HUMAN Zinc finger protein 248 ZNF248 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.92394 -1.048 LLLDIRHEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.69985 0 0 0 0 0 0 0 0 9.99039 Q8NDW8 TT21A_HUMAN Tetratricopeptide repeat protein 21A (TPR repeat protein 21A) (Stress-inducible protein 2) TTC21A STI2 Homo sapiens (Human) flagellated sperm motility [GO:0030317]; intraciliary retrograde transport [GO:0035721]; protein localization to cilium [GO:0061512]; spermatid development [GO:0007286] cilium [GO:0005929]; intraciliary transport particle A [GO:0030991] 0.96743 -3.7005 FDLALELLR 0 8.88481 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NDX1 PSD4_HUMAN PH and SEC7 domain-containing protein 4 (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 B) (Exchange factor for ARF6 B) (Pleckstrin homology and SEC7 domain-containing protein 4) (Telomeric of interleukin-1 cluster protein) PSD4 EFA6B TIC Homo sapiens (Human) regulation of ARF protein signal transduction [GO:0032012] membrane [GO:0016020]; ruffle membrane [GO:0032587] guanyl-nucleotide exchange factor activity [GO:0005085]; phospholipid binding [GO:0005543] 0.92315 -1.1532 EAGGTREPK 0 0 0 0 0 0 0 0 0 0 0 0 9.21133 0 0 10.1957 0 0 0 0 0 0 0 0 0 0 0 Q8NDX5 PHC3_HUMAN Polyhomeotic-like protein 3 (Early development regulatory protein 3) (Homolog of polyhomeotic 3) (hPH3) PHC3 EDR3 PH3 Homo sapiens (Human) nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PcG protein complex [GO:0031519]; PRC1 complex [GO:0035102] DNA binding [GO:0003677]; zinc ion binding [GO:0008270] 0.94736 -1.3475 ERERELR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7188 Q8NDY3 ARHL1_HUMAN Inactive ADP-ribosyltransferase ARH2 (ADP-ribosylhydrolase-like protein 1) ([Protein ADP-ribosylarginine] hydrolase-like protein 1) ADPRHL1 ARH2 Homo sapiens (Human) cardiac chamber ballooning [GO:0003242]; cardiac myofibril assembly [GO:0055003]; protein de-ADP-ribosylation [GO:0051725] sarcomere [GO:0030017] ADP-ribosylarginine hydrolase activity [GO:0003875]; magnesium ion binding [GO:0000287] 0.95316 -1.4863 IQEELQR 0 0 0 0 0 0 9.84706 9.80927 10.0101 0 0 0 0 0 0 0 0 0 0 0 0 0 10.138 0 0 0 0 Q8NDZ2 SIMC1_HUMAN SUMO-interacting motif-containing protein 1 (Platform element for inhibition of autolytic degradation) SIMC1 C5orf25 PLEIAD Homo sapiens (Human) negative regulation of peptidase activity [GO:0010466] cytoplasm [GO:0005737]; sarcomere [GO:0030017] peptidase inhibitor activity [GO:0030414]; SUMO polymer binding [GO:0032184] 0.91654 -0.8474 LEPIPHRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.71586 0 0 0 0 Q8NDZ4 DIK2A_HUMAN Divergent protein kinase domain 2A (Deleted in autism protein 1) (Golgi Protein of 49 kDa) (GoPro49) (Hypoxia and AKT-induced stem cell factor) (HASF) DIPK2A C3orf58 DIA1 Homo sapiens (Human) cardiac muscle cell proliferation [GO:0060038]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; positive regulation of protein kinase C activity [GO:1900020]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] COPI vesicle coat [GO:0030126]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139] 0.72471 0.35557 NELTDRRFLQLNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.62015 0 0 0 0 0 0 9.9202 Q8NE09 RGS22_HUMAN Regulator of G-protein signaling 22 (RGS22) RGS22 Homo sapiens (Human) negative regulation of signal transduction [GO:0009968] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; nucleus [GO:0005634] G-protein alpha-subunit binding [GO:0001965] 0.96973 -4.4156 EEFSLSQPPK 0 9.47927 9.1219 0 9.8375 0 0 0 15.2254 0 0 0 0 8.68433 0 0 0 0 0 0 0 10.4792 0 9.24332 0 0 0 Q8NE18 NSUN7_HUMAN Putative methyltransferase NSUN7 (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 7) NSUN7 Homo sapiens (Human) methylation [GO:0032259] methyltransferase activity [GO:0008168]; RNA binding [GO:0003723] 0.93217 -1.2747 DHSQGGISVDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.5041 Q8NE28 STKL1_HUMAN Serine/threonine kinase-like domain-containing protein STKLD1 (Serine/threonine kinase-like domain-containing protein 1) (Sugen kinase 071) STKLD1 C9orf96 SGK071 Homo sapiens (Human) protein phosphorylation [GO:0006468] ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674] 0.64145 0.3965 LGPGSNR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.59156 0 0 0 0 0 0 0 0 0 0 0 0 8.55654 Q8NE31 FA13C_HUMAN Protein FAM13C FAM13C FAM13C1 Homo sapiens (Human) 0.95964 -1.7293 ALLPDEKK 9.82144 0 0 0 0 0 0 0 0 10.7722 8.73481 9.07007 0 0 9.10392 0 0 0 0 0 0 0 0 0 0 0 0 Q8NE35 CPEB3_HUMAN Cytoplasmic polyadenylation element-binding protein 3 (CPE-BP3) (CPE-binding protein 3) (hCPEB-3) CPEB3 KIAA0940 Homo sapiens (Human) "3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to amino acid stimulus [GO:0071230]; long-term memory [GO:0007616]; negative regulation of cytoplasmic translation [GO:2000766]; negative regulation of cytoplasmic translational elongation [GO:1900248]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of translation [GO:0017148]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of mRNA polyadenylation [GO:1900365]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of translation [GO:0045727]; regulation of dendritic spine development [GO:0060998]; regulation of synaptic plasticity [GO:0048167]" apical dendrite [GO:0097440]; CCR4-NOT complex [GO:0030014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; messenger ribonucleoprotein complex [GO:1990124]; midbody [GO:0030496]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; synapse [GO:0045202] "mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA regulatory element binding translation repressor activity [GO:0000900]; ribosome binding [GO:0043022]; RNA binding [GO:0003723]; RNA stem-loop binding [GO:0035613]; translation factor activity, RNA binding [GO:0008135]" 0.95251 -1.4577 MQDDLLMDKSKTQPQPQQQQR 0 0 0 0 12.9732 0 0 0 0 11.5817 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NE65 ZN738_HUMAN Zinc finger protein 738 ZNF738 Homo sapiens (Human) protein polyubiquitination [GO:0000209]; regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872]; ubiquitin-protein transferase activity [GO:0004842] 0.95423 -1.5119 DPWNMKR 0 0 0 0 0 8.09845 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NE79 POPD1_HUMAN Blood vessel epicardial substance (hBVES) (Popeye domain-containing protein 1) (Popeye protein 1) BVES POP1 POPDC1 Homo sapiens (Human) cell migration involved in heart development [GO:0060973]; epithelial cell-cell adhesion [GO:0090136]; heart development [GO:0007507]; hematopoietic progenitor cell differentiation [GO:0002244]; muscle organ development [GO:0007517]; positive regulation of locomotion [GO:0040017]; positive regulation of receptor recycling [GO:0001921]; regulation of cell shape [GO:0008360]; regulation of endocytic recycling [GO:2001135]; regulation of GTPase activity [GO:0043087]; regulation of heart rate [GO:0002027]; regulation of membrane potential [GO:0042391]; response to ischemia [GO:0002931]; sinoatrial node cell development [GO:0060931]; skeletal muscle tissue development [GO:0007519]; striated muscle cell differentiation [GO:0051146]; substrate adhesion-dependent cell spreading [GO:0034446]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192] bicellular tight junction [GO:0005923]; caveola [GO:0005901]; cell junction [GO:0030054]; cell projection membrane [GO:0031253]; lateral plasma membrane [GO:0016328]; membrane [GO:0016020]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383] cAMP binding [GO:0030552]; structural molecule activity [GO:0005198] 0.94026 -1.3108 IEKELSGMYRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.3285 0 0 0 0 0 0 0 0 Q8NE86 MCU_HUMAN "Calcium uniporter protein, mitochondrial (HsMCU) (Coiled-coil domain-containing protein 109A)" MCU C10orf42 CCDC109A Homo sapiens (Human) actin filament reorganization [GO:0090527]; calcium import into the mitochondrion [GO:0036444]; calcium-mediated signaling [GO:0019722]; glucose homeostasis [GO:0042593]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transmembrane transport [GO:0006851]; positive regulation of insulin secretion [GO:0032024]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of neutrophil chemotaxis [GO:0090023]; protein complex oligomerization [GO:0051259] calcium channel complex [GO:0034704]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; uniplex complex [GO:1990246] calcium channel activity [GO:0005262]; identical protein binding [GO:0042802]; uniporter activity [GO:0015292] 0.96872 -3.9077 LPSRRER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.9219 0 0 0 0 0 10.3429 0 0 Q8NEA6 GLIS3_HUMAN Zinc finger protein GLIS3 (GLI-similar 3) (Zinc finger protein 515) GLIS3 ZNF515 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.88854 -0.40569 CTFEGCEKAFSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.7921 0 0 0 0 0 0 0 0 0 0 Q8NEB9 PK3C3_HUMAN Phosphatidylinositol 3-kinase catalytic subunit type 3 (PI3-kinase type 3) (PI3K type 3) (PtdIns-3-kinase type 3) (EC 2.7.1.137) (Phosphatidylinositol 3-kinase p100 subunit) (Phosphoinositide-3-kinase class 3) (hVps34) PIK3C3 VPS34 Homo sapiens (Human) autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of peroxisome [GO:0030242]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; endosome organization [GO:0007032]; macroautophagy [GO:0016236]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation by host of viral genome replication [GO:0044829]; protein lipidation [GO:0006497]; protein localization to phagophore assembly site [GO:0034497]; protein phosphorylation [GO:0006468]; protein processing [GO:0016485]; protein targeting to lysosome [GO:0006622]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241]; regulation of protein secretion [GO:0050708]; response to leucine [GO:0043201]; selective autophagy [GO:0061912] "autolysosome [GO:0044754]; axoneme [GO:0005930]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; late endosome [GO:0005770]; membrane [GO:0016020]; midbody [GO:0030496]; peroxisome [GO:0005777]; phagocytic vesicle membrane [GO:0030670]; phagophore assembly site [GO:0000407]; phosphatidylinositol 3-kinase complex, class III [GO:0035032]; phosphatidylinositol 3-kinase complex, class III, type I [GO:0034271]; phosphatidylinositol 3-kinase complex, class III, type II [GO:0034272]" 1-phosphatidylinositol-3-kinase activity [GO:0016303]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; phosphatidylinositol kinase activity [GO:0052742]; protein kinase activity [GO:0004672] 0.92167 -1.1193 AHRQGHMVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1875 0 0 0 0 0 10.3116 0 0 0 0 Q8NEC5 CTSR1_HUMAN Cation channel sperm-associated protein 1 (CatSper1) (hCatSper) CATSPER1 Homo sapiens (Human) calcium ion transport [GO:0006816]; cell differentiation [GO:0030154]; flagellated sperm motility [GO:0030317]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296]; regulation of monoatomic ion transmembrane transport [GO:0034765]; spermatogenesis [GO:0007283] CatSper complex [GO:0036128]; plasma membrane [GO:0005886]; sperm principal piece [GO:0097228] calcium activated cation channel activity [GO:0005227]; voltage-gated calcium channel activity [GO:0005245] 0.9137 -0.80141 FFRSHSSPPHHRPGHSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0323 0 0 0 0 0 0 Q8NEC7 GSTCD_HUMAN Glutathione S-transferase C-terminal domain-containing protein GSTCD Homo sapiens (Human) cytoplasm [GO:0005737]; extracellular exosome [GO:0070062] 0.82938 0.20566 LSEPVRVHNDDKLR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1675 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NEE6 FXL13_HUMAN F-box and leucine-rich repeat protein 13 (Dynein regulatory complex subunit 6) (F-box/LRR-repeat protein 13) FBXL13 DRC6 FBL13 Homo sapiens (Human) SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] cytoskeleton [GO:0005856]; cytosol [GO:0005829]; motile cilium [GO:0031514]; SCF ubiquitin ligase complex [GO:0019005] 0.9149 -0.78053 DIARTNENVVLAEKMNR 0 0 0 0 0 0 8.88059 0 0 0 0 0 0 0 0 0 0 0 0 9.34096 0 0 0 0 0 0 0 Q8NEF3 CC112_HUMAN Coiled-coil domain-containing protein 112 (Mutated in bladder cancer protein 1) CCDC112 MBC1 Homo sapiens (Human) centriolar satellite [GO:0034451]; cytoplasm [GO:0005737] 0.91533 -0.77094 TTNNELSAISRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.98 0 0 0 0 0 0 0 0 0 0 Q8NEF9 SRFB1_HUMAN Serum response factor-binding protein 1 (SRF-dependent transcription regulation-associated protein) (p49/STRAP) SRFBP1 Homo sapiens (Human) maturation of SSU-rRNA [GO:0030490] 90S preribosome [GO:0030686]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] RNA binding [GO:0003723] 0.6096 0.4299 AAVQAFK 0 0 0 0 0 0 12.5088 0 0 0 0 0 9.87981 0 0 0 10.092 0 0 0 0 0 0 0 0 0 0 Q8NEG2 CG057_HUMAN Uncharacterized protein C7orf57 C7orf57 Homo sapiens (Human) 0.96288 -2.0909 AGTPLGPK 0 0 12.517 10.186 10.4113 10.4125 11.9835 12.4353 12.5109 12.5577 12.6159 12.7283 11.1008 11.3079 11.1745 11.9246 0 11.5209 0 0 0 0 0 0 0 0 0 Q8NEG4 FA83F_HUMAN Protein FAM83F FAM83F Homo sapiens (Human) signal transduction [GO:0007165] protein kinase binding [GO:0019901] 0.89067 -0.48061 FSSRLFSRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.28126 0 0 0 0 0 0 0 0 0 0 0 0 Q8NEG5 ZSWM2_HUMAN E3 ubiquitin-protein ligase ZSWIM2 (EC 2.3.2.27) (MEKK1-related protein X) (MEX) (RING-type E3 ubiquitin transferase ZSWIM2) (ZZ-type zinc finger-containing protein 2) (Zinc finger SWIM domain-containing protein 2) ZSWIM2 ZZZ2 Homo sapiens (Human) apoptotic process [GO:0006915]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; protein polyubiquitination [GO:0000209] protein self-association [GO:0043621]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.96939 -5.5875 ADEVVKYIDTKNEIEEK 0 0 0 0 0 10.4847 0 11.5627 0 0 0 0 0 0 0 0 10.1664 0 0 11.38 0 0 0 0 0 0 0 Q8NEG7 DEN6B_HUMAN Protein DENND6B (DENN domain-containing protein 6B) DENND6B FAM116B Homo sapiens (Human) cytosol [GO:0005829]; recycling endosome [GO:0055037] guanyl-nucleotide exchange factor activity [GO:0005085] 0.9013 -0.6944 IPSRVDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.36499 0 9.1598 9.45512 9.54967 0 0 11.3006 0 Q8NEH6 MNS1_HUMAN Meiosis-specific nuclear structural protein 1 MNS1 Homo sapiens (Human) cilium organization [GO:0044782]; left/right axis specification [GO:0070986]; meiotic cell cycle [GO:0051321]; positive regulation of cilium assembly [GO:0045724]; sperm axoneme assembly [GO:0007288] axonemal microtubule [GO:0005879]; axoneme [GO:0005930]; intermediate filament [GO:0005882]; motile cilium [GO:0031514]; nuclear envelope [GO:0005635]; sperm flagellum [GO:0036126] identical protein binding [GO:0042802] 0.96873 -8.0082 AQYYLDLEKQLEEQEKK 10.1385 0 0 0 9.41714 0 0 0 10.0485 0 0 9.05637 0 0 10.4026 0 0 0 0 0 8.18799 0 9.59865 0 0 11.4162 0 Q8NEJ9 NGDN_HUMAN Neuroguidin (Centromere accumulated nuclear protein 1) (CANu1) (EIF4E-binding protein) NGDN C14orf120 Homo sapiens (Human) "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of translation at postsynapse [GO:0140245]; ribosomal small subunit biogenesis [GO:0042274]" "axon [GO:0030424]; chromosome, centromeric region [GO:0000775]; dendrite [GO:0030425]; filopodium [GO:0030175]; glutamatergic synapse [GO:0098978]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; perforant pathway to dendrate granule cell synapse [GO:0140240]; postsynapse [GO:0098794]; small-subunit processome [GO:0032040]" RNA binding [GO:0003723]; translation regulator activity [GO:0045182] 0.88334 -0.069928 GLSFLEVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4981 0 0 0 0 0 0 0 0 0 0 Q8NEK5 ZN548_HUMAN Zinc finger protein 548 ZNF548 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.9696 -4.7929 HQRVHTGERPYECRECGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.79352 0 0 0 0 0 Q8NEL9 DDHD1_HUMAN Phospholipase DDHD1 (EC 3.1.1.111) (EC 3.1.1.32) (DDHD domain-containing protein 1) (Phosphatidic acid-preferring phospholipase A1 homolog) (PA-PLA1) (EC 3.1.1.118) (Phospholipid sn-1 acylhydrolase) DDHD1 KIAA1705 Homo sapiens (Human) lipid metabolic process [GO:0006629]; positive regulation of mitochondrial fission [GO:0090141] cytoplasm [GO:0005737]; cytosol [GO:0005829] metal ion binding [GO:0046872]; phospholipase A1 activity [GO:0008970]; phospholipase activity [GO:0004620] 0.94069 -1.3299 DSMEDEK 0 0 0 0 0 0 0 10.2758 0 0 0 0 0 0 0 0 0 0 0 0 0 9.93356 0 0 0 0 0 Q8NEM1 ZN680_HUMAN Zinc finger protein 680 ZNF680 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96346 -2.1344 AFNQFANLTR 0 0 0 0 0 0 0 13.9937 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.46375 0 0 9.33409 Q8NEM2 SHCBP_HUMAN SHC SH2 domain-binding protein 1 SHCBP1 Homo sapiens (Human) fibroblast growth factor receptor signaling pathway [GO:0008543]; regulation of neural precursor cell proliferation [GO:2000177] cytoplasm [GO:0005737]; midbody [GO:0030496]; spindle [GO:0005819] SH2 domain binding [GO:0042169] 0.56497 0.49668 AVWHTNVFK 0 0 0 0 9.97083 0 0 9.06741 0 0 0 0 0 0 9.83211 0 0 0 0 0 0 0 0 0 10.3658 0 0 Q8NEM7 SP20H_HUMAN Transcription factor SPT20 homolog (p38-interacting protein) (p38IP) SUPT20H C13orf19 FAM48A FP757 Homo sapiens (Human) autophagy [GO:0006914]; gastrulation [GO:0007369]; histone H3 acetylation [GO:0043966]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA repair [GO:0006282]; regulation of RNA splicing [GO:0043484]; regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634]; SAGA complex [GO:0000124]; SAGA-type complex [GO:0070461] transcription coregulator activity [GO:0003712] 0.9298 -1.2439 AEYVIESAR 0 0 0 0 8.58278 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4192 0 0 0 0 0 0 Q8NEM8 CBPC3_HUMAN Cytosolic carboxypeptidase 3 (EC 3.4.17.-) (ATP/GTP-binding protein-like 3) (Protein deglutamylase CCP3) AGBL3 CCP3 Homo sapiens (Human) protein side chain deglutamylation [GO:0035610]; proteolysis [GO:0006508] cytosol [GO:0005829] metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270] 0.96955 -5.0708 AVILTARVHPGETNSSWIMK 0 0 0 0 8.75118 0 0 0 8.84699 0 0 9.68857 0 0 0 14.319 0 9.42156 9.84757 0 0 0 9.93795 10.8934 0 0 0 Q8NEN9 PDZD8_HUMAN PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR-104) PDZD8 PDZK8 Homo sapiens (Human) cytoskeleton organization [GO:0007010]; lipid transport [GO:0006869]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrion-endoplasmic reticulum membrane tethering [GO:1990456]; regulation of cell morphogenesis [GO:0022604] endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; mitochondria-associated endoplasmic reticulum membrane [GO:0044233]; mitochondrion [GO:0005739] lipid binding [GO:0008289]; metal ion binding [GO:0046872] 0.96916 -4.8586 AQNEFKDEAQSLSHSPK 0 0 11.2091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4121 0 0 0 0 0 9.6512 10.5575 0 Q8NER1 TRPV1_HUMAN Transient receptor potential cation channel subfamily V member 1 (TrpV1) (Capsaicin receptor) (Osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) TRPV1 VR1 Homo sapiens (Human) behavioral response to pain [GO:0048266]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; cell surface receptor signaling pathway [GO:0007166]; cellular response to acidic pH [GO:0071468]; cellular response to alkaloid [GO:0071312]; cellular response to ATP [GO:0071318]; cellular response to heat [GO:0034605]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to temperature stimulus [GO:0071502]; cellular response to tumor necrosis factor [GO:0071356]; chemosensory behavior [GO:0007635]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; detection of temperature stimulus involved in thermoception [GO:0050960]; diet induced thermogenesis [GO:0002024]; fever generation [GO:0001660]; glutamate secretion [GO:0014047]; lipid metabolic process [GO:0006629]; microglial cell activation [GO:0001774]; negative regulation of establishment of blood-brain barrier [GO:0090212]; negative regulation of heart rate [GO:0010459]; negative regulation of mitochondrial membrane potential [GO:0010917]; negative regulation of systemic arterial blood pressure [GO:0003085]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptide secretion [GO:0002790]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of gastric acid secretion [GO:0060454]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; protein homotetramerization [GO:0051289]; response to capsazepine [GO:1901594]; response to peptide hormone [GO:0043434]; sensory perception of mechanical stimulus [GO:0050954]; smooth muscle contraction involved in micturition [GO:0060083]; thermoception [GO:0050955] cytosol [GO:0005829]; dendritic spine membrane [GO:0032591]; external side of plasma membrane [GO:0009897]; membrane [GO:0016020]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211] ATP binding [GO:0005524]; calcium channel activity [GO:0005262]; calcium-release channel activity [GO:0015278]; calmodulin binding [GO:0005516]; chloride channel regulator activity [GO:0017081]; excitatory extracellular ligand-gated monoatomic ion channel activity [GO:0005231]; extracellular ligand-gated monoatomic ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; phosphatidylinositol binding [GO:0035091]; phosphoprotein binding [GO:0051219]; temperature-gated ion channel activity [GO:0097603]; transmembrane signaling receptor activity [GO:0004888]; voltage-gated calcium channel activity [GO:0005245] 0.93048 -1.2392 LLQDKWDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.258 10.0957 10.271 10.1167 0 0 0 Q8NES3 LFNG_HUMAN "Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase)" LFNG Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; compartment pattern specification [GO:0007386]; marginal zone B cell differentiation [GO:0002315]; negative regulation of Notch signaling pathway involved in somitogenesis [GO:1902367]; ovarian follicle development [GO:0001541]; positive regulation of meiotic cell cycle [GO:0051446]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of protein binding [GO:0032092]; regulation of Notch signaling pathway [GO:0008593]; regulation of somitogenesis [GO:0014807]; somitogenesis [GO:0001756]; T cell differentiation [GO:0030217] extracellular region [GO:0005576]; extracellular vesicle [GO:1903561]; Golgi membrane [GO:0000139] metal ion binding [GO:0046872]; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity [GO:0033829] 0.75554 0.30768 HTGNVVITNCSAAHSRQALSCKMAVEYDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7186 0 0 0 0 0 0 0 0 0 Q8NES8 DB124_HUMAN "Beta-defensin 124 (Beta-defensin 24) (DEFB-24) (Defensin, beta 124)" DEFB124 DEFB24 Homo sapiens (Human) cellular response to peptidoglycan [GO:0071224]; defense response to bacterium [GO:0042742]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; innate immune response [GO:0045087]; positive regulation of chemokine (C-C motif) ligand 5 production [GO:0071651]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine production [GO:0032722]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of monocyte chemotaxis [GO:0090026] extracellular region [GO:0005576] 0.95509 -1.5789 CWKGQGACQTYCTR 0 0 0 0 0 0 0 0 0 12.3133 0 0 0 0 0 10.7987 0 0 0 0 0 0 0 0 0 0 0 Q8NET4 RTL9_HUMAN Retrotransposon Gag-like protein 9 (Retrotransposon gag domain-containing protein 1) (Tumor antigen BJ-HCC-23) RTL9 KIAA1318 RGAG1 Homo sapiens (Human) 0.95449 -1.5042 ATASGKMSTPLR 0 0 0 0 0 0 10.0541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NET5 NFAM1_HUMAN NFAT activation molecule 1 (Calcineurin/NFAT-activating ITAM-containing protein) (NFAT-activating protein with ITAM motif 1) NFAM1 CNAIP Homo sapiens (Human) B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; positive regulation of B cell receptor signaling pathway [GO:0050861]; positive regulation of cytokine production [GO:0001819]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; regulation of B cell differentiation [GO:0045577]; signal transduction [GO:0007165] azurophil granule membrane [GO:0035577]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886] transmembrane signaling receptor activity [GO:0004888] 0.9081 -0.74061 ENQPVRWR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.65367 9.21662 0 0 0 0 0 0 Q8NET8 TRPV3_HUMAN Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3) TRPV3 Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; negative regulation of hair cycle [GO:0042636]; positive regulation of calcium ion import [GO:0090280]; response to heat [GO:0009408] plasma membrane [GO:0005886]; receptor complex [GO:0043235] calcium channel activity [GO:0005262]; identical protein binding [GO:0042802] 0.92078 -0.91584 MGELCKVAEDDFR 0 0 9.82747 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NEU8 DP13B_HUMAN "DCC-interacting protein 13-beta (Dip13-beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2)" APPL2 DIP13B Homo sapiens (Human) "adiponectin-activated signaling pathway [GO:0033211]; cell cycle [GO:0007049]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cold acclimation [GO:0009631]; diet induced thermogenesis [GO:0002024]; glucose homeostasis [GO:0042593]; negative regulation of cellular response to insulin stimulus [GO:1900077]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fatty acid oxidation [GO:0046322]; negative regulation of glucose import [GO:0046325]; negative regulation of neural precursor cell proliferation [GO:2000178]; negative regulation of neurogenesis [GO:0050768]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [GO:1905451]; positive regulation of macropinocytosis [GO:1905303]; positive regulation of phagocytosis, engulfment [GO:0060100]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; regulation of fibroblast migration [GO:0010762]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of innate immune response [GO:0045088]; regulation of toll-like receptor 4 signaling pathway [GO:0034143]; signal transduction [GO:0007165]; signaling [GO:0023052]; transforming growth factor beta receptor signaling pathway [GO:0007179]" cytoplasmic vesicle [GO:0031410]; early endosome membrane [GO:0031901]; early phagosome [GO:0032009]; early phagosome membrane [GO:0036186]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; macropinosome [GO:0044354]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; vesicle [GO:0031982] identical protein binding [GO:0042802]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877] 0.41925 0.68059 AGYLNLR 0 10.8073 0 0 0 0 11.1766 11.3216 0 0 0 0 0 0 9.51627 10.3716 10.2363 0 0 0 0 0 0 0 0 0 0 Q8NEV1 CSK23_HUMAN Casein kinase II subunit alpha 3 (CK II alpha 3) (EC 2.7.11.1) (Casein kinase II alpha 1 polypeptide pseudogene) CSNK2A3 CSNK2A1P Homo sapiens (Human) peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein catabolic process [GO:0045732]; protein phosphorylation [GO:0006468] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein kinase CK2 complex [GO:0005956] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.88558 -0.33294 LLRYDHQSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.35727 0 0 Q8NEV4 MYO3A_HUMAN Myosin-IIIa (EC 2.7.11.1) MYO3A Homo sapiens (Human) cochlea morphogenesis [GO:0090103]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of filopodium assembly [GO:0051491]; protein autophosphorylation [GO:0046777]; regulation of actin filament length [GO:0030832]; response to stimulus [GO:0050896]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; filopodium tip [GO:0032433]; myosin complex [GO:0016459]; photoreceptor inner segment [GO:0001917]; stereocilium tip [GO:0032426] actin binding [GO:0003779]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; microfilament motor activity [GO:0000146]; plus-end directed microfilament motor activity [GO:0060002]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96003 -1.8972 AAVFIQSK 0 0 0 0 0 0 0 0 0 0 0 0 9.69302 0 0 0 0 0 0 9.78576 0 0 0 0 0 0 0 Q8NEV8 EXPH5_HUMAN Exophilin-5 (Synaptotagmin-like protein homolog lacking C2 domains b) (SlaC2-b) (Slp homolog lacking C2 domains b) EXPH5 KIAA0624 SLAC2B Homo sapiens (Human) intracellular protein transport [GO:0006886]; keratinocyte development [GO:0003334]; multivesicular body sorting pathway [GO:0071985]; positive regulation of exocytosis [GO:0045921]; positive regulation of protein secretion [GO:0050714] endosome [GO:0005768] small GTPase binding [GO:0031267] 0.95678 -1.6486 EIFSDNLAK 10.003 0 0 0 0 0 9.0571 9.06469 0 0 10.2779 10.6074 0 9.26782 0 0 0 0 9.05864 0 0 0 0 12.186 11.2266 0 0 Q8NEW7 TMIE_HUMAN Transmembrane inner ear expressed protein TMIE Homo sapiens (Human) inner ear morphogenesis [GO:0042472]; sensory perception of sound [GO:0007605] membrane [GO:0016020] 0.92286 -1.0742 EIEARYLQR 0 0 0 8.8117 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NEY1 NAV1_HUMAN Neuron navigator 1 (Pore membrane and/or filament-interacting-like protein 3) (Steerin-1) (Unc-53 homolog 1) (unc53H1) NAV1 KIAA1151 KIAA1213 POMFIL3 STEERIN1 Homo sapiens (Human) microtubule bundle formation [GO:0001578]; neuron migration [GO:0001764] axon initial segment [GO:0043194]; cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630] 0.96922 -4.8329 AAAADGRGMLPK 0 0 0 0 0 9.26388 0 0 8.68643 0 0 0 10.7409 0 0 0 0 0 0 8.65252 0 0 0 0 0 0 0 Q8NEY4 VATC2_HUMAN V-type proton ATPase subunit C 2 (V-ATPase subunit C 2) (Vacuolar proton pump subunit C 2) ATP6V1C2 Homo sapiens (Human) positive regulation of Wnt signaling pathway [GO:0030177]; regulation of macroautophagy [GO:0016241] "cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lysosomal membrane [GO:0005765]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]" "identical protein binding [GO:0042802]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]" 0.81846 0.21861 SEFWLISAPGDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.62082 0 0 0 0 0 0 0 0 0 Q8NEY8 PPHLN_HUMAN Periphilin-1 (CDC7 expression repressor) (CR) (Gastric cancer antigen Ga50) PPHLN1 HSPC206 HSPC232 Homo sapiens (Human) "keratinization [GO:0031424]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression, epigenetic [GO:0045814]; positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309]; protein localization to heterochromatin [GO:0097355]" chromosome [GO:0005694]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654] RNA binding [GO:0003723] 0.92287 -1.0746 MWSEGRYEYER 0 8.74933 9.02351 0 0 0 9.30672 9.56302 9.51899 0 9.03158 9.32876 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NEZ2 VP37A_HUMAN Vacuolar protein sorting-associated protein 37A (hVps37A) (ESCRT-I complex subunit VPS37A) (Hepatocellular carcinoma-related protein 1) VPS37A HCRP1 Homo sapiens (Human) macroautophagy [GO:0016236]; membrane fission [GO:0090148]; multivesicular body assembly [GO:0036258]; protein targeting to membrane [GO:0006612]; protein targeting to vacuole [GO:0006623]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding via host ESCRT complex [GO:0039702] centrosome [GO:0005813]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; ESCRT I complex [GO:0000813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; nucleoplasm [GO:0005654] 0.8907 -0.46116 MEIDDFLSSFMEK 0 0 0 0 10.7148 0 0 0 0 0 0 0 10.1497 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NEZ3 WDR19_HUMAN WD repeat-containing protein 19 (Intraflagellar transport 144 homolog) WDR19 IFT144 KIAA1638 Homo sapiens (Human) cell morphogenesis [GO:0000902]; ciliary receptor clustering involved in smoothened signaling pathway [GO:0060830]; cilium assembly [GO:0060271]; digestive system development [GO:0055123]; ear morphogenesis [GO:0042471]; embryonic camera-type eye development [GO:0031076]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic limb morphogenesis [GO:0030326]; gonad development [GO:0008406]; in utero embryonic development [GO:0001701]; intraciliary retrograde transport [GO:0035721]; myotome development [GO:0061055]; nervous system process [GO:0050877]; protein localization to ciliary membrane [GO:1903441]; protein-containing complex assembly [GO:0065003]; smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] ciliary tip [GO:0097542]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; intraciliary transport particle A [GO:0030991]; motile cilium [GO:0031514]; non-motile cilium [GO:0097730]; photoreceptor connecting cilium [GO:0032391]; photoreceptor outer segment [GO:0001750] 0.92475 -0.98593 CPSSEDNVAIEMAIETVGQAK 0 0 0 0 0 9.35955 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0233 Q8NEZ4 KMT2C_HUMAN Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.364) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3) KMT2C HALR KIAA1506 MLL3 Homo sapiens (Human) histone H3-K4 methylation [GO:0051568]; positive regulation of transcription by RNA polymerase II [GO:0045944] histone methyltransferase complex [GO:0035097]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] acyltransferase activity [GO:0016746]; DNA binding [GO:0003677]; histone binding [GO:0042393]; histone H3K4 methyltransferase activity [GO:0042800]; histone H3K4 monomethyltransferase activity [GO:0140945]; histone H3K4 trimethyltransferase activity [GO:0140999]; histone methyltransferase activity [GO:0042054]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; transcription coactivator activity [GO:0003713] 0.92704 -1.1902 AETESCPGQEEPK 0 9.16005 9.15104 0 0 9.58474 0 0 0 9.33764 9.181 0 0 0 0 0 0 12.6069 0 0 0 0 0 0 0 0 9.53906 Q8NEZ5 FBX22_HUMAN F-box only protein 22 (F-box protein FBX22p44) FBXO22 FBX22 Homo sapiens (Human) cellular response to starvation [GO:0009267]; nucleocytoplasmic transport [GO:0006913]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein modification process [GO:0036211]; protein polyubiquitination [GO:0000209]; regulation of skeletal muscle fiber development [GO:0048742]; ubiquitin-dependent protein catabolic process [GO:0006511] cytosol [GO:0005829]; nucleus [GO:0005634]; Z disc [GO:0030018] ubiquitin-protein transferase activity [GO:0004842] 0.96806 -2.7822 IQPFHFIKDPK 0 0 0 0 0 0 0 0 9.47342 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1777 0 0 Q8NF50 DOCK8_HUMAN Dedicator of cytokinesis protein 8 DOCK8 Homo sapiens (Human) cellular response to chemokine [GO:1990869]; dendritic cell migration [GO:0036336]; immunological synapse formation [GO:0001771]; memory T cell proliferation [GO:0061485]; negative regulation of T cell apoptotic process [GO:0070233]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of GTPase activity [GO:0043547]; positive regulation of T cell migration [GO:2000406]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264] cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] guanyl-nucleotide exchange factor activity [GO:0005085] 0.96907 -4.834 DLSKDQHGR 0 0 0 0 0 0 0 8.78777 0 8.96113 0 0 10.8876 0 0 9.9474 0 0 0 0 0 9.83567 0 10.4453 0 0 0 Q8NF91 SYNE1_HUMAN Nesprin-1 (Enaptin) (KASH domain-containing protein 1) (KASH1) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) SYNE1 C6orf98 KIAA0796 KIAA1262 KIAA1756 MYNE1 Homo sapiens (Human) Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]; nucleus organization [GO:0006997]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; Golgi apparatus [GO:0005794]; meiotic nuclear membrane microtubule tethering complex [GO:0034993]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; postsynaptic membrane [GO:0045211]; sarcomere [GO:0030017] actin binding [GO:0003779]; actin filament binding [GO:0051015]; cytoskeleton-nuclear membrane anchor activity [GO:0140444]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; lamin binding [GO:0005521]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723] 0.96881 -12.048 ALQDLADLLETGQEK 12.3736 11.0823 12.6665 11.5238 12.1918 11.3323 11.7795 8.66683 11.6855 13.8757 13.9956 10.3989 11.9122 10.7777 10.2766 11.6672 0 10.7315 0 10.6984 10.1248 9.76737 8.90406 10.4167 0 9.96207 0 Q8NF99 ZN397_HUMAN Zinc finger protein 397 (Zinc finger and SCAN domain-containing protein 15) (Zinc finger protein 47) ZNF397 ZNF47 ZSCAN15 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; regulation of transcription by RNA polymerase II [GO:0006357] cytoplasm [GO:0005737]; cytosol [GO:0005829]; microtubule cytoskeleton [GO:0015630]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.91581 -0.76883 AFSLRSYLIIHQR 0 0 0 0 0 0 0 0 10.6781 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NFA0 UBP32_HUMAN Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.4.19.12) (Deubiquitinating enzyme 32) (Renal carcinoma antigen NY-REN-60) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) USP32 USP10 Homo sapiens (Human) protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; membrane [GO:0016020] calcium ion binding [GO:0005509]; cysteine-type deubiquitinase activity [GO:0004843] 0.88871 -0.41122 DAFKRTCGLSYYMGQHCFIR 13.1375 12.6984 0 10.3232 0 0 13.55 0 12.9707 0 0 0 0 0 0 0 12.1481 0 0 0 0 8.64281 0 0 0 0 0 Q8NFA2 NOXO1_HUMAN NADPH oxidase organizer 1 (NADPH oxidase regulatory protein) (Nox organizer 1) (Nox-organizing protein 1) (SH3 and PX domain-containing protein 5) NOXO1 P41NOX SH3PXD5 Homo sapiens (Human) extracellular matrix disassembly [GO:0022617]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of respiratory burst [GO:0060263]; superoxide anion generation [GO:0042554] NADPH oxidase complex [GO:0043020]; plasma membrane [GO:0005886] enzyme binding [GO:0019899]; phosphatidylinositol binding [GO:0035091]; phospholipid binding [GO:0005543]; superoxide-generating NADPH oxidase activator activity [GO:0016176] 0.9669 -2.3196 VGRTSRGLAR 0 0 0 0 9.7446 0 0 0 0 12.2478 12.8039 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NFC6 BD1L1_HUMAN Biorientation of chromosomes in cell division protein 1-like 1 BOD1L1 BOD1L FAM44A KIAA1327 Homo sapiens (Human) DNA damage response [GO:0006974]; DNA repair [GO:0006281]; histone H3-K4 methylation [GO:0051568]; replication fork processing [GO:0031297] chromosome [GO:0005694]; nucleoplasm [GO:0005654]; Set1C/COMPASS complex [GO:0048188] 0.96741 -2.7964 CPGPVRGGK 14.5486 11.6005 11.7031 0 9.5215 9.57824 9.29834 11.1366 0 11.302 12.1371 14.9667 8.73373 0 0 0 0 0 0 0 0 8.85353 0 10.1938 0 0 0 Q8NFD2 ANKK1_HUMAN Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (Sugen kinase 288) (SgK288) (X-kinase) ANKK1 PKK2 SGK288 Homo sapiens (Human) protein phosphorylation [GO:0006468]; regulation of cell cycle process [GO:0010564] cell projection [GO:0042995]; cytoplasm [GO:0005737]; nucleus [GO:0005634] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.88387 -0.16312 VAVPESK 0 0 11.8549 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NFD5 ARI1B_HUMAN AT-rich interactive domain-containing protein 1B (ARID domain-containing protein 1B) (BRG1-associated factor 250b) (BAF250B) (BRG1-binding protein hELD/OSA1) (Osa homolog 2) (hOsa2) (p250R) ARID1B BAF250B DAN15 KIAA1235 OSA2 Homo sapiens (Human) cellular response to angiotensin [GO:1904385]; chromatin remodeling [GO:0006338]; nervous system development [GO:0007399]; positive regulation of cell differentiation [GO:0045597]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of T cell differentiation [GO:0045582]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357]; response to ischemia [GO:0002931]; transcription initiation-coupled chromatin remodeling [GO:0045815] bBAF complex [GO:0140092]; brahma complex [GO:0035060]; chromatin [GO:0000785]; cytosol [GO:0005829]; nBAF complex [GO:0071565]; npBAF complex [GO:0071564]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; SWI/SNF complex [GO:0016514] DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713] 0.96148 -2.5936 EEDEDKGVACSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7071 0 9.48925 0 0 0 0 0 8.91316 0 0 Q8NFF5 FAD1_HUMAN FAD synthase (EC 2.7.7.2) (FAD pyrophosphorylase) (FMN adenylyltransferase) (Flavin adenine dinucleotide synthase) [Includes: Molybdenum cofactor biosynthesis protein-like region; FAD synthase region] FLAD1 PP591 Homo sapiens (Human) FAD biosynthetic process [GO:0006747]; riboflavin metabolic process [GO:0006771] cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; FMN adenylyltransferase activity [GO:0003919]; identical protein binding [GO:0042802] 0.89858 -0.55496 GLFQNPAVQFHSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.45022 0 0 0 Q8NFG4 FLCN_HUMAN Folliculin (BHD skin lesion fibrofolliculoma protein) (Birt-Hogg-Dube syndrome protein) FLCN BHD Homo sapiens (Human) cell proliferation involved in kidney development [GO:0072111]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid starvation [GO:0034198]; cellular response to starvation [GO:0009267]; energy homeostasis [GO:0097009]; epithelial cell proliferation [GO:0050673]; ERK1 and ERK2 cascade [GO:0070371]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; intrinsic apoptotic signaling pathway [GO:0097193]; lysosome localization [GO:0032418]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation involved in kidney development [GO:1901723]; negative regulation of cellular respiration [GO:1901856]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of gene expression [GO:0010629]; negative regulation of glycolytic process [GO:0045820]; negative regulation of mitochondrial DNA metabolic process [GO:1901859]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of muscle tissue development [GO:1901862]; negative regulation of post-translational protein modification [GO:1901874]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of TOR signaling [GO:0032007]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of autophagy [GO:0010508]; positive regulation of cell adhesion [GO:0045785]; positive regulation of GTPase activity [GO:0043547]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of TOR signaling [GO:0032008]; positive regulation of TORC1 signaling [GO:1904263]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein kinase B signaling [GO:0043491]; regulation of cytokinesis [GO:0032465]; regulation of histone acetylation [GO:0035065]; regulation of pro-B cell differentiation [GO:2000973]; regulation of protein phosphorylation [GO:0001932]; regulation of Ras protein signal transduction [GO:0046578]; regulation of TOR signaling [GO:0032006]; TOR signaling [GO:0031929]; transforming growth factor beta receptor signaling pathway [GO:0007179] centrosome [GO:0005813]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; mitotic spindle [GO:0072686]; nucleus [GO:0005634]; plasma membrane [GO:0005886] enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTPase activator activity [GO:0005096]; protein-containing complex binding [GO:0044877] 0.94906 -1.3797 EGPIFFGDEQHGFVFSHTFFIK 0 0 0 0 0 0 0 0 0 9.39932 0 9.24959 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NFH8 REPS2_HUMAN RalBP1-associated Eps domain-containing protein 2 (Partner of RalBP1) (RalBP1-interacting protein 2) REPS2 POB1 Homo sapiens (Human) endocytosis [GO:0006897]; endosomal transport [GO:0016197]; epidermal growth factor receptor signaling pathway [GO:0007173]; protein-containing complex assembly [GO:0065003] cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.56125 0.534 LIAAAQSGLPVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.313 Q8NFI3 ENASE_HUMAN Cytosolic endo-beta-N-acetylglucosaminidase (ENGase) (EC 3.2.1.96) ENGASE Homo sapiens (Human) protein deglycosylation [GO:0006517]; protein folding [GO:0006457] cytosol [GO:0005829] "hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity [GO:0033925]" 0.917 -0.86057 GWVRTHCCLEDAWHGGSSLLVR 0 0 0 0 0 0 0 0 0 0 0 0 9.46191 9.24194 0 0 9.57766 9.32728 0 0 0 0 0 0 0 0 0 Q8NFJ5 RAI3_HUMAN Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Phorbol ester induced gene 1) (PEIG-1) (Retinoic acid-induced gene 1 protein) (RAIG-1) GPRC5A GPCR5A RAI3 RAIG1 Homo sapiens (Human) negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; signal transduction [GO:0007165] cytoplasmic vesicle membrane [GO:0030659]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; vesicle [GO:0031982] cadherin binding [GO:0045296]; G protein-coupled receptor activity [GO:0004930]; protein kinase activator activity [GO:0030295] 0.76503 0.28199 ATTVPDGCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8108 10.6949 10.8321 0 0 0 0 0 0 Q8NFJ8 BHE22_HUMAN Class E basic helix-loop-helix protein 22 (bHLHe22) (Class B basic helix-loop-helix protein 5) (bHLHb5) (Trinucleotide repeat-containing gene 20 protein) BHLHE22 BHLHB5 TNRC20 Homo sapiens (Human) axon development [GO:0061564]; neuron fate commitment [GO:0048663]; positive regulation of transcription by RNA polymerase II [GO:0045944]; sensory organ development [GO:0007423] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; E-box binding [GO:0070888]; protein dimerization activity [GO:0046983]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96388 -2.6498 ALRLNINARER 0 0 0 0 0 0 0 0 0 9.18108 0 0 8.2075 8.80909 8.33485 10.302 0 0 0 9.91195 10.2333 0 9.23721 9.16972 0 0 0 Q8NFJ9 BBS1_HUMAN Bardet-Biedl syndrome 1 protein (BBS2-like protein 2) BBS1 BBS2L2 Homo sapiens (Human) adult behavior [GO:0030534]; brain morphogenesis [GO:0048854]; cartilage development [GO:0051216]; cellular lipid metabolic process [GO:0044255]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; dendrite development [GO:0016358]; fat cell differentiation [GO:0045444]; fertilization [GO:0009566]; Golgi to plasma membrane protein transport [GO:0043001]; hippocampus development [GO:0021766]; hormone metabolic process [GO:0042445]; microtubule cytoskeleton organization [GO:0000226]; neural precursor cell proliferation [GO:0061351]; neuron migration [GO:0001764]; non-motile cilium assembly [GO:1905515]; olfactory behavior [GO:0042048]; photoreceptor cell maintenance [GO:0045494]; photoreceptor cell morphogenesis [GO:0008594]; protein localization to cilium [GO:0061512]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296]; sensory perception of smell [GO:0007608]; striatum development [GO:0021756]; ventricular system development [GO:0021591]; visual perception [GO:0007601] axoneme [GO:0005930]; BBSome [GO:0034464]; centriolar satellite [GO:0034451]; centrosome [GO:0005813]; ciliary membrane [GO:0060170]; cytosol [GO:0005829]; motile cilium [GO:0031514] patched binding [GO:0005113]; phosphoprotein binding [GO:0051219]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; smoothened binding [GO:0005119] 0.87213 0.037014 NLADEDAVSCLVLGTENK 0 0 0 0 0 0 0 0 9.37467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NFM4 ADCY4_HUMAN Adenylate cyclase type 4 (EC 4.6.1.1) (ATP pyrophosphate-lyase 4) (Adenylate cyclase type IV) (Adenylyl cyclase 4) ADCY4 Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cAMP biosynthetic process [GO:0006171]; intracellular signal transduction [GO:0035556] cytoplasm [GO:0005737]; dendrite [GO:0030425]; membrane [GO:0016020]; plasma membrane [GO:0005886] adenylate cyclase activity [GO:0004016]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase C binding [GO:0005080] 0.57154 0.48032 EALSSLHSR 9.368 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4105 0 0 Q8NFN8 GP156_HUMAN Probable G-protein coupled receptor 156 (G-protein coupled receptor PGR28) (GABAB-related G-protein coupled receptor) GPR156 GABABL PGR28 Homo sapiens (Human) gamma-aminobutyric acid signaling pathway [GO:0007214] G protein-coupled receptor heterodimeric complex [GO:0038039]; plasma membrane [GO:0005886] G protein-coupled GABA receptor activity [GO:0004965] 0.9559 -1.5438 QSQTEPEGARGSK 0 0 10.0274 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NFP4 MDGA1_HUMAN MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (GPI and MAM protein) (GPIM) (Glycosylphosphatidylinositol-MAM) (MAM domain-containing protein 3) MDGA1 MAMDC3 Homo sapiens (Human) brain development [GO:0007420]; cerebral cortex radially oriented cell migration [GO:0021799]; nervous system development [GO:0007399]; neuron migration [GO:0001764]; regulation of presynapse assembly [GO:1905606]; regulation of synaptic membrane adhesion [GO:0099179]; spinal cord association neuron differentiation [GO:0021527] extracellular region [GO:0005576]; extracellular space [GO:0005615]; GABA-ergic synapse [GO:0098982]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886] 0.89911 -0.59079 TVFLRCTVNSNPPAR 0 0 0 0 0 0 0 8.37972 0 9.29356 0 0 0 0 0 0 0 0 0 0 0 0 0 10.478 0 0 0 Q8NFP9 NBEA_HUMAN Neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B) NBEA BCL8B KIAA1544 LYST2 Homo sapiens (Human) protein localization [GO:0008104] cytosol [GO:0005829]; endomembrane system [GO:0012505]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802] protein kinase binding [GO:0019901] 0.96893 -4.5413 ALEGPENCLFPR 0 9.95812 0 10.1629 9.54237 0 10.1854 9.86685 0 9.92689 0 0 0 9.04084 0 9.92117 10.1904 0 0 0 8.80851 0 0 8.69223 0 12.2384 0 Q8NFQ5 BPIB6_HUMAN BPI fold-containing family B member 6 (Bactericidal/permeability-increasing protein-like 3) BPIFB6 BPIL3 Homo sapiens (Human) extracellular region [GO:0005576] lipid binding [GO:0008289] 0.34509 0.77013 VTMKTGK 0 0 0 0 0 0 0 0 0 0 12.9749 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NFQ6 BPIFC_HUMAN BPI fold-containing family C protein (Bactericidal/permeability-increasing protein-like 2) (BPI-like 2) BPIFC BPIL2 Homo sapiens (Human) innate immune response [GO:0045087] extracellular space [GO:0005615] lipopolysaccharide binding [GO:0001530]; phospholipid binding [GO:0005543] 0.95414 -1.5265 MIEQMLKEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2717 0 0 0 0 0 0 0 0 Q8NFR7 CC148_HUMAN Coiled-coil domain-containing protein 148 CCDC148 Homo sapiens (Human) 0.96213 -2.6178 ILDHSLEEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.9639 0 0 0 0 10.7332 0 0 0 0 0 0 0 Q8NFR9 I17RE_HUMAN Interleukin-17 receptor E (IL-17 receptor E) (IL-17RE) IL17RE UNQ3056/PRO9877 Homo sapiens (Human) inflammatory response [GO:0006954] cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886] interleukin-17 receptor activity [GO:0030368] 0.96336 -2.2433 LELCSRLER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.111 0 0 Q8NFT2 STEA2_HUMAN Metalloreductase STEAP2 (EC 1.16.1.-) (Prostate cancer-associated protein 1) (Protein up-regulated in metastatic prostate cancer) (PUMPCn) (Six-transmembrane epithelial antigen of prostate 2) (SixTransMembrane protein of prostate 1) STEAP2 PCANAP1 STAMP1 UNQ6507/PRO23203 Homo sapiens (Human) copper ion import [GO:0015677]; copper ion import across plasma membrane [GO:0098705]; endocytosis [GO:0006897]; Golgi to plasma membrane transport [GO:0006893]; iron ion import across plasma membrane [GO:0098711]; regulated exocytosis [GO:0045055]; response to hormone [GO:0009725] cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; trans-Golgi network transport vesicle [GO:0030140] cupric reductase activity [GO:0008823]; ferric-chelate reductase (NADPH) activity [GO:0052851]; metal ion binding [GO:0046872] 0.90626 -0.71943 DASRQVYICSNNIQAR 9.3271 0 0 0 15.618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.82509 Q8NFU1 BEST2_HUMAN Bestrophin-2 (Vitelliform macular dystrophy 2-like protein 1) BEST2 VMD2L1 Homo sapiens (Human) membrane depolarization [GO:0051899]; sensory perception of smell [GO:0007608] chloride channel complex [GO:0034707]; cilium [GO:0005929]; plasma membrane [GO:0005886] chloride channel activity [GO:0005254] 0.84301 0.15187 TVTYTAR 0 0 10.4543 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NFU5 IPMK_HUMAN "Inositol polyphosphate multikinase (EC 2.7.1.140) (EC 2.7.1.151) (EC 2.7.1.153) (Inositol 1,3,4,6-tetrakisphosphate 5-kinase)" IPMK IMPK Homo sapiens (Human) inositol phosphate biosynthetic process [GO:0032958]; inositol phosphate metabolic process [GO:0043647]; inositol trisphosphate metabolic process [GO:0032957]; necroptotic process [GO:0070266] cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "ATP binding [GO:0005524]; flavonoid binding [GO:0097243]; inositol tetrakisphosphate 3-kinase activity [GO:0000824]; inositol tetrakisphosphate 5-kinase activity [GO:0047326]; inositol tetrakisphosphate 6-kinase activity [GO:0000825]; inositol tetrakisphosphate kinase activity [GO:0051765]; inositol-1,4,5-trisphosphate 3-kinase activity [GO:0008440]; inositol-1,4,5-trisphosphate 6-kinase activity [GO:0000823]; metal ion binding [GO:0046872]; myo-inositol-1,2,3,4,6-heptakisphosphate 5-kinase activity [GO:0102732]; phosphatidylinositol-3,4-bisphosphate 5-kinase activity [GO:0052812]; phosphatidylinositol-4,5-bisphosphate 3-kinase activity [GO:0046934]" 0.96113 -2.5958 ILQWFENQK 0 0 0 0 0 0 0 0 11.3003 8.99811 0 0 0 0 0 0 0 10.1654 0 0 0 0 0 0 0 0 0 Q8NFU7 TET1_HUMAN Methylcytosine dioxygenase TET1 (EC 1.14.11.80) (CXXC-type zinc finger protein 6) (Leukemia-associated protein with a CXXC domain) (Ten-eleven translocation 1 gene protein) TET1 CXXC6 KIAA1676 LCX Homo sapiens (Human) 5-methylcytosine catabolic process [GO:0006211]; chromatin remodeling [GO:0006338]; DNA demethylation [GO:0080111]; inner cell mass cell differentiation [GO:0001826]; negative regulation of cell migration [GO:0030336]; negative regulation of DNA methylation-dependent heterochromatin formation [GO:0090310]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; oxidative demethylation [GO:0070989]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein O-linked glycosylation [GO:0006493]; stem cell population maintenance [GO:0019827] nucleus [GO:0005634]; Sin3 complex [GO:0016580] DNA binding [GO:0003677]; iron ion binding [GO:0005506]; methyl-CpG binding [GO:0008327]; methylcytosine dioxygenase activity [GO:0070579]; zinc ion binding [GO:0008270] 0.96405 -2.649 IDPSSPLHEK 0 0 0 8.92062 9.29928 9.2274 0 10.0334 0 0 0 0 0 0 0 10.8153 0 0 10.0712 0 0 0 0 0 0 9.79433 0 Q8NFW1 COMA1_HUMAN Collagen alpha-1(XXII) chain COL22A1 Homo sapiens (Human) extracellular matrix organization [GO:0030198] collagen trimer [GO:0005581]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] extracellular matrix structural constituent [GO:0005201] 0.96761 -2.9473 AACGKVR 0 0 0 0 0 0 11.3832 0 0 0 0 0 0 9.41066 0 0 0 8.88896 8.75552 0 0 8.40689 0 0 10.3723 10.8334 8.96599 Q8NFW8 NEUA_HUMAN N-acylneuraminate cytidylyltransferase (EC 2.7.7.43) (CMP-N-acetylneuraminic acid synthase) (CMP-NeuNAc synthase) CMAS Homo sapiens (Human) N-acetylneuraminate metabolic process [GO:0006054] membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] N-acylneuraminate cytidylyltransferase activity [GO:0008781] 0.886 -0.33663 LISERACSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.37084 0 0 0 0 0 0 0 0 0 0 0 0 Q8NFW9 MYRIP_HUMAN Rab effector MyRIP (Exophilin-8) (Myosin-VIIa- and Rab-interacting protein) (Synaptotagmin-like protein lacking C2 domains C) (SlaC2-c) (Slp homolog lacking C2 domains c) MYRIP SLAC2C Homo sapiens (Human) intracellular protein transport [GO:0006886]; positive regulation of insulin secretion [GO:0032024] cortical actin cytoskeleton [GO:0030864]; dense core granule [GO:0031045]; exocyst [GO:0000145]; melanosome [GO:0042470]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor outer segment [GO:0001750]; synapse [GO:0045202]; transport vesicle [GO:0030133] actin binding [GO:0003779]; myosin binding [GO:0017022]; protein kinase A binding [GO:0051018]; small GTPase binding [GO:0031267]; zinc ion binding [GO:0008270] 0.96999 -5.0201 EPSSPSAQLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.8835 0 0 0 0 0 0 Q8NFX7 STXB6_HUMAN Syntaxin-binding protein 6 (Amisyn) STXBP6 HSPC156 Homo sapiens (Human) negative regulation of exocytosis [GO:0045920]; regulation of SNARE complex assembly [GO:0035542]; SNARE complex assembly [GO:0035493] adherens junction [GO:0005912]; cytoplasm [GO:0005737]; membrane [GO:0016020] cadherin binding involved in cell-cell adhesion [GO:0098641] 0.83029 0.20684 KPTQASITK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.64035 0 0 0 0 0 0 Q8NFY4 SEM6D_HUMAN Semaphorin-6D SEMA6D KIAA1479 Homo sapiens (Human) negative chemotaxis [GO:0050919]; negative regulation of axon extension [GO:0030517]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of smooth muscle cell migration [GO:0014912]; neural crest cell migration [GO:0001755]; positive regulation of cell migration [GO:0030335]; positive regulation of smooth muscle cell migration [GO:0014911]; semaphorin-plexin signaling pathway [GO:0071526]; smooth muscle cell migration [GO:0014909]; ventricular system development [GO:0021591] cell surface [GO:0009986]; cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886] chemorepellent activity [GO:0045499]; semaphorin receptor binding [GO:0030215] 0.92395 -1.1698 IRDTLYIAGR 0 0 0 0 0 0 0 0 0 0 10.9438 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NFY9 KBTB8_HUMAN Kelch repeat and BTB domain-containing protein 8 (T-cell activation kelch repeat protein) (TA-KRP) KBTBD8 KIAA1842 TAKRP Homo sapiens (Human) neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; protein monoubiquitination [GO:0006513]; regulation of translation [GO:0006417] Cul3-RING ubiquitin ligase complex [GO:0031463]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; spindle [GO:0005819] 0.73037 0.33427 IVGVEAESMDLVLNYAYTSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.90418 11.0929 0 0 Q8NFZ0 FBH1_HUMAN F-box DNA helicase 1 (hFBH1) (EC 5.6.2.4) (DNA 3'-5' helicase 1) (F-box only protein 18) FBH1 FBX18 FBXO18 Homo sapiens (Human) DNA catabolic process [GO:0006308]; DNA damage response [GO:0006974]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of chromatin binding [GO:0035562]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902231]; positive regulation of protein phosphorylation [GO:0001934]; protein ubiquitination [GO:0016567]; replication fork processing [GO:0031297]; response to intra-S DNA damage checkpoint signaling [GO:0072429] chromatin [GO:0000785]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005] 3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA helicase activity [GO:0003678]; DNA translocase activity [GO:0015616]; double-stranded DNA binding [GO:0003690]; isomerase activity [GO:0016853]; single-stranded DNA binding [GO:0003697] 0.86841 0.071773 IPELVQRIEK 0 0 0 9.22185 9.21485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NFZ4 NLGN2_HUMAN Neuroligin-2 NLGN2 KIAA1366 Homo sapiens (Human) "brain development [GO:0007420]; cell-cell adhesion [GO:0098609]; cell-cell junction maintenance [GO:0045217]; chemical synaptic transmission [GO:0007268]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; inhibitory synapse assembly [GO:1904862]; insulin metabolic process [GO:1901142]; jump response [GO:0007630]; locomotory exploration behavior [GO:0035641]; modulation of chemical synaptic transmission [GO:0050804]; neuromuscular process controlling balance [GO:0050885]; neuron cell-cell adhesion [GO:0007158]; neurotransmitter-gated ion channel clustering [GO:0072578]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of insulin secretion [GO:0032024]; positive regulation of protein localization to synapse [GO:1902474]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of synaptic vesicle clustering [GO:2000809]; positive regulation of t-SNARE clustering [GO:1904034]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein localization to cell surface [GO:0034394]; protein localization to synapse [GO:0035418]; regulation of AMPA receptor activity [GO:2000311]; regulation of presynapse assembly [GO:1905606]; regulation of respiratory gaseous exchange by nervous system process [GO:0002087]; sensory perception of pain [GO:0019233]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse organization [GO:0050808]; synaptic transmission, GABAergic [GO:0051932]; synaptic vesicle endocytosis [GO:0048488]; terminal button organization [GO:0072553]; thigmotaxis [GO:0001966]" "cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendritic shaft [GO:0043198]; dopaminergic synapse [GO:0098691]; excitatory synapse [GO:0060076]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; postsynaptic specialization membrane [GO:0099634]; presynaptic membrane [GO:0042734]; ribbon synapse [GO:0097470]; symmetric, GABA-ergic, inhibitory synapse [GO:0098983]; synapse [GO:0045202]" cell adhesion molecule binding [GO:0050839]; identical protein binding [GO:0042802]; neurexin family protein binding [GO:0042043]; signaling receptor activity [GO:0038023] 0.91714 -0.86044 ELVDQDVQPAR 0 0 0 0 9.63535 0 0 0 0 0 0 0 0 0 0 0 0 0 8.74648 0 0 0 0 0 0 0 0 Q8NFZ5 TNIP2_HUMAN TNFAIP3-interacting protein 2 (A20-binding inhibitor of NF-kappa-B activation 2) (ABIN-2) (Fetal liver LKB1-interacting protein) TNIP2 ABIN2 FLIP1 Homo sapiens (Human) apoptotic process [GO:0006915]; CD40 signaling pathway [GO:0023035]; cellular response to lipopolysaccharide [GO:0071222]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; negative regulation of endothelial cell apoptotic process [GO:2000352]; positive regulation of B cell activation [GO:0050871]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macrophage activation [GO:0043032]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein stabilization [GO:0050821]; regulation of transcription by RNA polymerase II [GO:0006357]; toll-like receptor 2 signaling pathway [GO:0034134]; toll-like receptor 3 signaling pathway [GO:0034138]; toll-like receptor 9 signaling pathway [GO:0034162] cytosol [GO:0005829]; nucleoplasm [GO:0005654] K63-linked polyubiquitin modification-dependent protein binding [GO:0070530]; metal ion binding [GO:0046872]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein kinase binding [GO:0019901] 0.9231 -1.055 LTERLEEK 0 0 0 0 0 0 0 0 0 0 0 8.80151 0 0 0 11.0179 0 0 10.3203 0 0 10.1028 0 0 0 10.9807 10.9136 Q8NG04 S2610_HUMAN Putative solute carrier family 26 member 10P SLC26A10P SLC26A10 Homo sapiens (Human) basolateral plasma membrane [GO:0016323] antiporter activity [GO:0015297]; bicarbonate transmembrane transporter activity [GO:0015106]; chloride transmembrane transporter activity [GO:0015108]; oxalate transmembrane transporter activity [GO:0019531]; sulfate transmembrane transporter activity [GO:0015116] 0.78562 0.24934 LDLASLMSAPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2786 0 0 Q8NG08 HELB_HUMAN DNA helicase B (hDHB) (EC 3.6.4.12) HELB Homo sapiens (Human) "DNA damage response [GO:0006974]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, synthesis of RNA primer [GO:0006269]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; regulation of DNA double-strand break processing [GO:1903775]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861] 5'-3' DNA helicase activity [GO:0043139]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; protein-containing complex binding [GO:0044877]; single-stranded DNA helicase activity [GO:0017116] 0.96947 -4.6047 ETGRKDQK 0 0 0 14.3576 9.42127 0 0 0 0 0 0 8.85745 0 0 0 0 0 0 0 9.70662 0 9.91331 0 0 0 0 0 Q8NG11 TSN14_HUMAN Tetraspanin-14 (Tspan-14) (DC-TM4F2) (Transmembrane 4 superfamily member 14) TSPAN14 TM4SF14 Homo sapiens (Human) positive regulation of Notch signaling pathway [GO:0045747]; protein localization to plasma membrane [GO:0072659]; protein maturation [GO:0051604] cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; tetraspanin-enriched microdomain [GO:0097197] enzyme binding [GO:0019899] 0.89876 -0.64694 HYYRYSNAK 0 0 0 0 0 0 0 0 0 10.9305 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NG27 PJA1_HUMAN E3 ubiquitin-protein ligase Praja-1 (Praja1) (EC 2.3.2.27) (RING finger protein 70) (RING-type E3 ubiquitin transferase Praja-1) PJA1 RNF70 Homo sapiens (Human) protein catabolic process [GO:0030163] cytoplasm [GO:0005737] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630] 0.86421 0.085921 DTANDNEGHSDGLAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.93605 0 0 0 0 0 Q8NG31 KNL1_HUMAN Kinetochore scaffold 1 (ALL1-fused gene from chromosome 15q14 protein) (AF15q14) (Bub-linking kinetochore protein) (Blinkin) (Cancer susceptibility candidate gene 5 protein) (Cancer/testis antigen 29) (CT29) (Kinetochore-null protein 1) (Protein CASC5) (Protein D40/AF15q14) KNL1 CASC5 KIAA1570 Homo sapiens (Human) acrosome assembly [GO:0001675]; attachment of spindle microtubules to kinetochore [GO:0008608]; cell division [GO:0051301]; protein localization to kinetochore [GO:0034501] acrosomal vesicle [GO:0001669]; cytosol [GO:0005829]; kinetochore [GO:0000776]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.82915 0.20425 CSAFPDVPDK 0 0 0 0 11.6318 0 0 0 0 0 0 0 0 13.2689 0 0 0 0 0 0 0 0 0 11.0099 13.4073 13.2268 10.0055 Q8NG35 D105A_HUMAN "Beta-defensin 105 (Beta-defensin 5) (BD-5) (DEFB-5) (Defensin, beta 105)" DEFB105A BD5 DEFB105 DEFB5; DEFB105B Homo sapiens (Human) defense response to bacterium [GO:0042742]; innate immune response [GO:0045087] extracellular region [GO:0005576] 0.88466 -0.28667 ECLENEKPDGNCR 9.43619 0 0 0 0 0 0 9.83719 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NG48 LINES_HUMAN Protein Lines homolog 1 (Wnt-signaling molecule Lines homolog 1) LINS1 LINS WINS1 Homo sapiens (Human) cognition [GO:0050890] 0.84957 0.11604 FQNYSSASEVKVDLQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0347 0 0 0 0 0 10.5543 0 Q8NG66 NEK11_HUMAN Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (Never in mitosis A-related kinase 11) (NimA-related protein kinase 11) NEK11 Homo sapiens (Human) intracellular signal transduction [GO:0035556]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; protein phosphorylation [GO:0006468]; regulation of mitotic cell cycle phase transition [GO:1901990] nucleolus [GO:0005730]; nucleoplasm [GO:0005654] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.9323 -1.2868 KLQAADEKAR 8.83848 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NG78 OR8G5_HUMAN Olfactory receptor 8G5 (Olfactory receptor 8G6) (Olfactory receptor OR11-298) OR8G5 OR8G5P OR8G6 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; sensory perception of smell [GO:0007608] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; odorant binding [GO:0005549]; olfactory receptor activity [GO:0004984] 0.88355 -0.045507 ENNNTIHLNTMFFLSPAETHQR 0 12.2359 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NG80 OR2L5_HUMAN Olfactory receptor 2L5 (Olfactory receptor 2L11) (Olfactory receptor OR1-53) OR2L5 OR2L11 Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of smell [GO:0050911] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.95499 -1.5218 SLRSLTEDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1236 0 0 0 0 0 0 Q8NG99 OR7G2_HUMAN Olfactory receptor 7G2 (OST260) (Olfactory receptor 19-13) (OR19-13) (Olfactory receptor OR19-6) OR7G2 Homo sapiens (Human) signal transduction [GO:0007165] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.6637 0.39426 MPSASGK 0 0 0 0 0 0 0 0 0 0 10.8985 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NGA1 OR1M1_HUMAN Olfactory receptor 1M1 (Olfactory receptor 19-6) (OR19-6) (Olfactory receptor OR19-5) OR1M1 Homo sapiens (Human) signal transduction [GO:0007165] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.75742 0.30063 LSCTDTSVNR 0 0 0 0 0 0 0 0 0 0 0 0 10.236 10.5104 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NGC1 O11G2_HUMAN Olfactory receptor 11G2 (Olfactory receptor OR14-34) OR11G2 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.67708 0.39371 VPSAAGR 0 0 0 13.7397 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NGC6 OR4KH_HUMAN Olfactory receptor 4K17 (Olfactory receptor OR14-29) OR4K17 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.94007 -1.3268 ISMKKLWR 0 0 0 0 0 0 0 0 0 0 0 0 11.8375 0 0 0 0 0 0 0 0 0 0 10.1289 0 0 0 Q8NGC9 O11H4_HUMAN Olfactory receptor 11H4 (Olfactory receptor OR14-36) OR11H4 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.86621 0.074574 SFFFVDLRPMNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.78852 0 0 0 0 0 Q8NGD2 OR4K2_HUMAN Olfactory receptor 4K2 (Olfactory receptor OR14-15) OR4K2 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.9542 -1.5223 NRFLNFNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7091 0 0 0 0 0 0 0 0 0 0 Q8NGD3 OR4K5_HUMAN Olfactory receptor 4K5 (Olfactory receptor OR14-16) OR4K5 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.96175 -2.5603 SSAAMAK 0 0 0 0 0 0 0 0 0 0 8.46156 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NGD5 OR4KE_HUMAN Olfactory receptor 4K14 (Olfactory receptor OR14-22) OR4K14 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.63828 0.39716 AAGSTSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.392 0 10.7505 0 0 0 0 0 0 Q8NGF0 O52B6_HUMAN Olfactory receptor 52B6 (Olfactory receptor OR11-47) OR52B6 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.95393 -1.5332 MAQVRALHK 0 0 0 0 0 0 0 8.87086 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NGF1 O52R1_HUMAN Olfactory receptor 52R1 (Olfactory receptor OR11-22) OR52R1 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.88066 0.0062362 FGHDVPR 0 0 0 0 0 0 0 0 0 0 0 0 9.55029 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NGF8 OR4B1_HUMAN Olfactory receptor 4B1 (OST208) (Olfactory receptor OR11-106) OR4B1 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.93144 -1.2722 IAIRRLWSK 0 0 0 0 10.3597 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NGH6 O52L2_HUMAN Putative olfactory receptor 52L2 (Olfactory receptor OR11-74) OR52L2P OR52L2 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.88462 -0.33427 VPGNEARLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.88594 0 0 0 0 0 0 0 Q8NGI2 O52N4_HUMAN Olfactory receptor 52N4 (Olfactory receptor OR11-64) OR52N4 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.72138 0.364 VGTATFLR 0 11.4505 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NGI4 OR4DB_HUMAN Olfactory receptor 4D11 OR4D11 OR4D11P Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.63534 0.39744 SQAGGGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.6647 0 0 0 0 0 9.77517 0 0 0 Q8NGJ1 OR4D6_HUMAN Olfactory receptor 4D6 (Olfactory receptor OR11-250) OR4D6 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.67107 0.39371 SHSGEGR 0 10.0307 0 0 0 0 0 0 0 8.62374 9.92972 8.81622 0 8.72356 0 0 0 0 8.71908 0 8.5635 0 0 0 0 0 0 Q8NGJ2 O52H1_HUMAN Olfactory receptor 52H1 (Olfactory receptor OR11-45) OR52H1 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.96148 -2.5603 FGHNVSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.28937 0 Q8NGJ3 O52E1_HUMAN Olfactory receptor 52E1 OR52E1 OR52E1P Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.96928 -3.3761 LSCASIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.29494 0 0 0 0 0 0 0 0 Q8NGJ7 O51A2_HUMAN Olfactory receptor 51A2 OR51A2 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.80273 0.24048 YTSILTTVR 9.09474 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NGJ8 O51S1_HUMAN Olfactory receptor 51S1 (Olfactory receptor OR11-24) OR51S1 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.95897 -1.7161 ILNRLQPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.97888 0 0 0 0 0 0 0 0 0 Q8NGK4 O52K1_HUMAN Olfactory receptor 52K1 (Olfactory receptor OR11-8) OR52K1 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.87735 -0.0056403 EYVLSLFQR 0 8.64731 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NGL6 O4A15_HUMAN Olfactory receptor 4A15 (Olfactory receptor OR11-118) OR4A15 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.38056 0.72219 MELLTNNLKFITDPFVCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8723 0 0 0 0 0 0 0 0 0 Q8NGM8 OR6M1_HUMAN Olfactory receptor 6M1 (Olfactory receptor OR11-271) OR6M1 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.78628 0.25532 LLACLLGEEK 0 0 0 9.09937 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2786 0 0 Q8NGM9 OR8D4_HUMAN Olfactory receptor 8D4 (Olfactory receptor OR11-275) OR8D4 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; sensory perception of smell [GO:0007608] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; odorant binding [GO:0005549]; olfactory receptor activity [GO:0004984] 0.87261 0.035161 LSFCGSNIIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.72612 0 Q8NGN4 O10G9_HUMAN Olfactory receptor 10G9 (Olfactory receptor 10G10) OR10G9 OR10G10P Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of smell [GO:0050911] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.84955 0.15624 IHTSEGR 0 0 0 8.99687 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NGN5 O10G8_HUMAN Olfactory receptor 10G8 (Olfactory receptor OR11-282) OR10G8 Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of smell [GO:0050911] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.63179 0.40474 LLMTLVFPSGR 0 0 0 0 8.87178 0 0 0 0 0 0 0 8.86879 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NGP2 OR8J1_HUMAN Olfactory receptor 8J1 (Olfactory receptor OR11-183) OR8J1 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; sensory perception of smell [GO:0007608] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; odorant binding [GO:0005549]; olfactory receptor activity [GO:0004984] 0.88427 -0.29836 FMTNLCYSFKTM 0 0 0 0 0 8.61578 0 0 0 0 0 0 0 0 0 8.99489 0 0 0 0 0 0 0 0 0 0 0 Q8NGQ1 OR9G4_HUMAN Olfactory receptor 9G4 (Olfactory receptor OR11-216) OR9G4 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; sensory perception of smell [GO:0007608] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; odorant binding [GO:0005549]; olfactory receptor activity [GO:0004984] 0.94037 -1.3108 ATQTIQPQT 0 0 0 0 0 0 0 0 10.4458 0 0 0 0 0 0 0 0 0 0 0 0 10.0267 0 0 0 0 0 Q8NGQ2 OR6Q1_HUMAN Olfactory receptor 6Q1 (Olfactory receptor OR11-226) OR6Q1 Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of smell [GO:0050911] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.87068 0.042204 VTSSINFNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.297 0 0 0 0 0 0 9.63005 0 0 0 Q8NGR4 OR5C1_HUMAN Olfactory receptor 5C1 (Olfactory receptor 5C2) (Olfactory receptor 9-F) (OR9-F) OR5C1 OR5C2P Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; odorant binding [GO:0005549]; olfactory receptor activity [GO:0004984] 0.93203 -1.2866 LSFCRSRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.96454 0 0 0 0 0 0 0 Q8NGR5 OR1L4_HUMAN Olfactory receptor 1L4 (OST046) (Olfactory receptor 1L5) (Olfactory receptor 9-E) (OR9-E) (Olfactory receptor OR9-29) OR1L4 OR1L5 Homo sapiens (Human) signal transduction [GO:0007165] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.87426 0.036093 LSFCASHIIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2804 0 0 0 0 0 0 0 0 0 0 0 Q8NGT0 O13C9_HUMAN Olfactory receptor 13C9 (Olfactory receptor OR9-13) OR13C9 Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of smell [GO:0050911] nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.84656 0.15391 IHSSEGR 0 0 0 0 0 10.4913 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NGT9 OR2A1_HUMAN Olfactory receptor 2A1/2A42 (Olfactory receptor OR7-16) (Olfactory receptor OR7-19) OR2A1; OR2A42 Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of smell [GO:0050911] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.95233 -1.4608 SRHPEEQQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5641 0 0 0 Q8NGW6 OR6K6_HUMAN Olfactory receptor 6K6 (Olfactory receptor OR1-21) OR6K6 Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of smell [GO:0050911] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; odorant binding [GO:0005549]; olfactory receptor activity [GO:0004984] 0.91642 -0.84756 LFHYQKR 0 0 0 0 0 0 0 0 9.4549 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NGX2 O2T35_HUMAN Olfactory receptor 2T35 (Olfactory receptor OR1-66) OR2T35 Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of smell [GO:0050911] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.88467 -0.28301 VLGRCGSSQSIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1941 0 0 Q8NGX9 OR6P1_HUMAN Olfactory receptor 6P1 (Olfactory receptor OR1-12) OR6P1 Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of smell [GO:0050911] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.92514 -0.9699 IPTSRGRHK 0 0 12.2694 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3602 0 0 0 0 0 0 0 0 0 Q8NGY0 O10X1_HUMAN Olfactory receptor 10X1 (Olfactory receptor OR1-14) OR10X1 OR10X1P Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.92704 -1.194 MLEDLLAKDR 0 0 0 0 0 0 0 0 0 0 0 9.28251 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NGY1 O10Z1_HUMAN Olfactory receptor 10Z1 (Olfactory receptor OR1-15) OR10Z1 Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of smell [GO:0050911] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; odorant binding [GO:0005549]; olfactory receptor activity [GO:0004984] 0.95363 -1.5003 NRAIQTALR 0 0 0 8.22139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NGZ2 O14K1_HUMAN Olfactory receptor 14K1 (Olfactory receptor 5AY1) (Olfactory receptor OR1-39) OR14K1 OR5AY1 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; odorant binding [GO:0005549]; olfactory receptor activity [GO:0004984] 0.88186 -0.1155 VLWNVRSSGVMKR 0 0 0 0 0 0 0 0 0 0 0 9.97585 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NH08 O10AC_HUMAN Olfactory receptor 10AC1 (Olfactory receptor OR7-5) OR10AC1 OR10AC1P Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of smell [GO:0050911] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.91668 -0.77417 SLVDLSTPGHRR 0 0 0 0 0 0 0 9.56702 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NH09 OR8S1_HUMAN Olfactory receptor 8S1 OR8S1 Homo sapiens (Human) signal transduction [GO:0007165] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.90715 -0.71764 RPAFTEGRR 0 0 0 0 0 0 0 0 0 0 0 11.4991 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NH37 OR4C3_HUMAN Olfactory receptor 4C3 (Olfactory receptor OR11-98) OR4C3 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.67748 0.39371 SHSADGR 0 0 0 0 0 0 9.83028 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NH40 OR6S1_HUMAN Olfactory receptor 6S1 (Olfactory receptor OR14-37) OR6S1 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.89919 -0.63698 LACTNTK 11.8672 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.86005 10.7702 9.34897 9.83556 0 0 0 Q8NH41 OR4KF_HUMAN Olfactory receptor 4K15 (Olfactory receptor OR14-20) OR4K15 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.89041 -0.48894 NKEVKAAMSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.82591 0 0 0 0 0 0 0 8.52974 0 Q8NH50 OR8K5_HUMAN Olfactory receptor 8K5 (Olfactory receptor OR11-174) OR8K5 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; sensory perception of smell [GO:0007608] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; odorant binding [GO:0005549]; olfactory receptor activity [GO:0004984] 0.91989 -0.90173 NAFYKLFEN 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.77703 0 0 0 0 0 0 0 0 0 0 0 0 Q8NH63 O51H1_HUMAN Olfactory receptor 51H1 (Olfactory receptor OR11-25) OR51H1 OR51H1P Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.94385 -1.3368 TVLGIVSRGERLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.62757 0 0 0 0 0 0 0 10.2328 0 Q8NH85 OR5R1_HUMAN Olfactory receptor 8U3 (Olfactory receptor 5R1) (Olfactory receptor OR11-185) OR8U3 OR5R1 OR5R1P Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; sensory perception of smell [GO:0007608] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; odorant binding [GO:0005549]; olfactory receptor activity [GO:0004984] 0.84402 0.15187 STQGQHK 0 0 0 0 0 10.4913 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NHC8 OR2T6_HUMAN Olfactory receptor 2T6 (OST703) (Olfactory receptor 2T9) OR2T6 OR2T6P OR2T9 Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of smell [GO:0050911] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.76098 0.29375 ILITVHQMTSAEGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.64474 9.55265 0 0 0 0 0 0 Q8NHH1 TTL11_HUMAN Tubulin polyglutamylase TTLL11 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 11) TTLL11 C9orf20 Homo sapiens (Human) microtubule cytoskeleton organization [GO:0000226]; microtubule severing [GO:0051013]; protein polyglutamylation [GO:0018095] ciliary basal body [GO:0036064]; cilium [GO:0005929]; cytosol [GO:0005829]; microtubule [GO:0005874] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; tubulin binding [GO:0015631]; tubulin-glutamic acid ligase activity [GO:0070740] 0.88533 -0.37065 AGEEQPK 0 0 0 0 0 0 8.30419 0 0 0 0 0 0 0 10.3425 0 0 0 9.52358 0 0 0 8.72686 0 0 0 0 Q8NHJ6 LIRB4_HUMAN Leukocyte immunoglobulin-like receptor subfamily B member 4 (B4) (CD85 antigen-like family member K) (Immunoglobulin-like transcript 3) (ILT-3) (Leukocyte immunoglobulin-like receptor 5) (LIR-5) (Monocyte inhibitory receptor HM18) (CD antigen CD85k) LILRB4 ILT3 LIR5 Homo sapiens (Human) "adaptive immune response [GO:0002250]; cytokine-mediated signaling pathway [GO:0019221]; Fc receptor mediated inhibitory signaling pathway [GO:0002774]; interleukin-10-mediated signaling pathway [GO:0140105]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of chemokine production [GO:0032682]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of cytotoxic T cell differentiation [GO:0045584]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of interleukin-5 production [GO:0032714]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of IP-10 production [GO:0071659]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of miRNA transcription [GO:1902894]; negative regulation of monocyte activation [GO:0150102]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of protein tyrosine kinase activity [GO:0061099]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of T cell costimulation [GO:2000524]; negative regulation of T cell cytokine production [GO:0002725]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of T cell anergy [GO:0002669]; receptor internalization [GO:0031623]; tolerance induction [GO:0002507]" cell surface [GO:0009986]; cytoplasmic side of plasma membrane [GO:0009898]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] apolipoprotein binding [GO:0034185]; fibronectin binding [GO:0001968]; inhibitory MHC class I receptor activity [GO:0032396]; protein phosphatase binding [GO:0019903]; signaling receptor inhibitor activity [GO:0030547]; transmembrane receptor protein tyrosine kinase inhibitor activity [GO:0030293] 0.8723 0.030088 NTQPEDGVEMDTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.80584 0 0 0 Q8NHK3 KI2LB_HUMAN Killer cell immunoglobulin-like receptor 2DL5B (CD158 antigen-like family member F2) (Killer cell immunoglobulin-like receptor 2DLX) (CD antigen CD158f2) KIR2DL5B CD158F CD158F2 KIR2DL5 KIR2DLX Homo sapiens (Human) plasma membrane [GO:0005886] 0.88092 0.014161 VASSHVPAAGI 0 0 0 0 0 0 0 9.4385 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NHM5 KDM2B_HUMAN Lysine-specific demethylase 2B (EC 1.14.11.27) (CXXC-type zinc finger protein 2) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (Protein JEMMA) (Protein-containing CXXC domain 2) ([Histone-H3]-lysine-36 demethylase 1B) KDM2B CXXC2 FBL10 FBXL10 JHDM1B NDY1 PCCX2 Homo sapiens (Human) chromatin remodeling [GO:0006338]; embryonic camera-type eye morphogenesis [GO:0048596]; forebrain development [GO:0030900]; fourth ventricle development [GO:0021592]; hindbrain development [GO:0030902]; initiation of neural tube closure [GO:0021993]; lateral ventricle development [GO:0021670]; midbrain development [GO:0030901]; midbrain-hindbrain boundary morphogenesis [GO:0021555]; negative regulation of neural precursor cell proliferation [GO:2000178]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell growth [GO:0030307]; positive regulation of stem cell population maintenance [GO:1902459]; protein demethylation [GO:0006482]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; third ventricle development [GO:0021678] chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PcG protein complex [GO:0031519] DNA binding [GO:0003677]; histone demethylase activity [GO:0032452]; histone H3K36 demethylase activity [GO:0051864]; histone H3K36me/H3K36me2 demethylase activity [GO:0140680]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; rRNA binding [GO:0019843]; transcription coregulator activity [GO:0003712]; unmethylated CpG binding [GO:0045322]; zinc ion binding [GO:0008270] 0.96953 -6.4389 APALRFLK 10.5183 8.55263 0 0 0 0 0 0 0 0 0 0 0 11.0128 9.40376 10.2877 0 0 0 0 0 0 0 0 9.74982 0 0 Q8NHP1 ARK74_HUMAN Aflatoxin B1 aldehyde reductase member 4 (EC 1.-.-.-) (AFB1 aldehyde reductase 3) (AFB1-AR 3) (Aldoketoreductase 7-like) AKR7L AFAR3 AKR7A4 Homo sapiens (Human) cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062] aldo-keto reductase (NADP) activity [GO:0004033] 0.88519 -0.24039 SQLETSLKR 14.2761 13.9089 14.3727 0 0 0 12.8614 13.3072 13.3626 0 0 13.272 0 11.7688 0 0 12.9793 0 0 0 0 0 0 0 0 0 0 Q8NHP6 MSPD2_HUMAN Motile sperm domain-containing protein 2 MOSPD2 Homo sapiens (Human) chemotaxis [GO:0006935]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neutrophil chemotaxis [GO:0090023] endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-endosome membrane contact site [GO:0140284]; membrane [GO:0016020]; organelle membrane contact site [GO:0044232]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579] 0.96977 -4.6931 EISVNDLNESSIPR 0 0 0 10.6245 0 0 0 0 0 0 9.3347 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NHP7 EXD1_HUMAN piRNA biogenesis protein EXD1 (Exonuclease 3'-5' domain-containing protein 1) (Exonuclease 3'-5' domain-like-containing protein 1) (Inactive exonuclease EXD1) EXD1 EXDL1 Homo sapiens (Human) meiotic cell cycle [GO:0051321]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047] P granule [GO:0043186]; PET complex [GO:1990923] protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723] 0.56616 0.49203 ITQKEHFMTPK 9.80468 0 0 0 0 0 0 0 10.2868 0 0 0 0 9.67299 0 0 0 0 0 0 0 0 9.39481 9.20914 0 0 0 Q8NHP8 PLBL2_HUMAN Putative phospholipase B-like 2 (EC 3.1.1.-) (76 kDa protein) (p76) (LAMA-like protein 2) (Lamina ancestor homolog 2) (Phospholipase B domain-containing protein 2) [Cleaved into: Putative phospholipase B-like 2 32 kDa form; Putative phospholipase B-like 2 45 kDa form] PLBD2 Homo sapiens (Human) phospholipid catabolic process [GO:0009395] extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202] phospholipase activity [GO:0004620] 0.913 -0.75618 YVRPRGCVLEWVR 0 0 10.0251 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NHQ1 CEP70_HUMAN Centrosomal protein of 70 kDa (Cep70) (p10-binding protein) CEP70 BITE Homo sapiens (Human) cilium assembly [GO:0060271]; regulation of microtubule cytoskeleton organization [GO:0070507] centrosome [GO:0005813]; cytosol [GO:0005829] gamma-tubulin binding [GO:0043015]; identical protein binding [GO:0042802] 0.95238 -1.4559 EQKTLQVK 0 0 0 0 0 0 0 0 0 0 0 0 0 8.60696 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NHQ8 RASF8_HUMAN Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1) RASSF8 C12orf2 Homo sapiens (Human) signal transduction [GO:0007165] 0.88283 -0.29982 LENGIKAVER 0 0 0 0 0 0 0 0 0 0 0 0 9.04442 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NHQ9 DDX55_HUMAN ATP-dependent RNA helicase DDX55 (EC 3.6.4.13) (DEAD box protein 55) DDX55 KIAA1595 Homo sapiens (Human) cytosol [GO:0005829]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.90554 -0.72599 CPLQEMKPQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.46074 Q8NHR7 TERB2_HUMAN Telomere repeats-binding bouquet formation protein 2 TERB2 C15orf43 Homo sapiens (Human) double-strand break repair involved in meiotic recombination [GO:1990918]; homologous chromosome pairing at meiosis [GO:0007129]; meiotic attachment of telomere to nuclear envelope [GO:0070197]; meiotic telomere clustering [GO:0045141]; oogenesis [GO:0048477]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130] "chromosome, telomeric region [GO:0000781]; nuclear inner membrane [GO:0005637]" 0.95916 -1.7161 ELSKSPEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.22224 Q8NHS0 DNJB8_HUMAN DnaJ homolog subfamily B member 8 DNAJB8 Homo sapiens (Human) chaperone-mediated protein folding [GO:0061077]; negative regulation of inclusion body assembly [GO:0090084] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] Hsp70 protein binding [GO:0030544]; protein folding chaperone [GO:0044183]; protein-folding chaperone binding [GO:0051087]; unfolded protein binding [GO:0051082] 0.94339 -1.3337 SLYDRAGCDSWR 0 0 0 0 10.213 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NHS2 AATC2_HUMAN "Putative aspartate aminotransferase, cytoplasmic 2 (EC 2.6.1.1) (Glutamate oxaloacetate transaminase 1-like protein 1) (Transaminase A-like protein 1)" GOT1L1 Homo sapiens (Human) aspartate biosynthetic process [GO:0006532] cytosol [GO:0005829] L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170] 0.86994 0.039062 EVVENIMLTK 0 0 0 0 0 0 0 0 0 0 0 0 9.46583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NHS3 MFSD8_HUMAN Major facilitator superfamily domain-containing protein 8 (Ceroid-lipofuscinosis neuronal protein 7) MFSD8 CLN7 Homo sapiens (Human) autophagosome maturation [GO:0097352]; lysosome organization [GO:0007040]; neuron development [GO:0048666]; regulation of autophagy [GO:0010506]; regulation of lysosomal protein catabolic process [GO:1905165]; TORC1 signaling [GO:0038202] lysosomal membrane [GO:0005765] transmembrane transporter activity [GO:0022857] 0.8701 0.059093 GVTWDVIK 0 0 0 0 0 0 0 0 9.46215 9.85936 0 0 9.51964 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NHS4 CLHC1_HUMAN Clathrin heavy chain linker domain-containing protein 1 CLHC1 C2orf63 Homo sapiens (Human) 0.924 -1.0441 FNELISLGEYEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.40958 0 0 Q8NHU2 CFA61_HUMAN Cilia- and flagella-associated protein 61 CFAP61 C20orf26 Homo sapiens (Human) cilium movement [GO:0003341]; cilium organization [GO:0044782] axoneme [GO:0005930]; motile cilium [GO:0031514] 0.81782 0.22043 MVETITCLSR 0 9.63152 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NHU3 SMS2_HUMAN Phosphatidylcholine:ceramide cholinephosphotransferase 2 (EC 2.7.8.27) (Sphingomyelin synthase 2) SGMS2 SMS2 Homo sapiens (Human) ceramide biosynthetic process [GO:0046513]; ceramide phosphoethanolamine biosynthetic process [GO:1905373]; phosphorylation [GO:0016310]; regulation of bone mineralization [GO:0030500]; sphingolipid biosynthetic process [GO:0030148]; sphingomyelin biosynthetic process [GO:0006686] Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] ceramide cholinephosphotransferase activity [GO:0047493]; ceramide phosphoethanolamine synthase activity [GO:0002950]; kinase activity [GO:0016301]; sphingomyelin synthase activity [GO:0033188] 0.81732 0.22072 VSSQTNFLSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.9847 0 0 0 0 0 0 Q8NHU6 TDRD7_HUMAN Tudor domain-containing protein 7 (PCTAIRE2-binding protein) (Tudor repeat associator with PCTAIRE-2) (Trap) TDRD7 PCTAIRE2BP Homo sapiens (Human) lens fiber cell differentiation [GO:0070306]; lens morphogenesis in camera-type eye [GO:0002089]; post-transcriptional regulation of gene expression [GO:0010608]; spermatogenesis [GO:0007283] chromatoid body [GO:0033391]; cytoplasm [GO:0005737]; ribonucleoprotein granule [GO:0035770] mRNA binding [GO:0003729] 0.96427 -2.2752 DYSAAQELMEDEMKEYYSK 8.38448 8.19081 8.18745 0 0 0 0 8.99831 0 0 8.85106 0 0 0 8.16133 0 0 0 0 0 0 0 0 0 0 0 0 Q8NHV1 GIMA7_HUMAN GTPase IMAP family member 7 (Immunity-associated nucleotide 7 protein) (IAN-7) GIMAP7 IAN7 Homo sapiens (Human) GTP metabolic process [GO:0046039] endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; lipid droplet [GO:0005811] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803] 0.96849 -3.8611 IAAQAVTKNCQKASR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.43915 0 0 Q8NHV4 NEDD1_HUMAN Protein NEDD1 (Neural precursor cell expressed developmentally down-regulated protein 1) (NEDD-1) NEDD1 Homo sapiens (Human) cell division [GO:0051301]; microtubule nucleation [GO:0007020]; mitotic cell cycle [GO:0000278] apical part of cell [GO:0045177]; centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; pericentriolar material [GO:0000242]; spindle pole [GO:0000922] gamma-tubulin binding [GO:0043015] 0.88592 -0.33893 IYMGKQESK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.96353 0 0 0 0 0 Q8NHX4 SPTA3_HUMAN Spermatogenesis-associated protein 3 (Testis and spermatogenesis cell-related protein 1) (Testis spermatocyte apoptosis-related protein 1) SPATA3 TSARG1 Homo sapiens (Human) 0.85007 0.16204 DWQMAPGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.57401 0 0 0 0 0 0 0 0 0 0 Q8NHX9 TPC2_HUMAN Two pore channel protein 2 (Two pore calcium channel protein 2) TPCN2 TPC2 Homo sapiens (Human) calcium-mediated signaling [GO:0019722]; endocytosis involved in viral entry into host cell [GO:0075509]; endosome to lysosome transport of low-density lipoprotein particle [GO:0090117]; intracellular calcium ion homeostasis [GO:0006874]; intracellular pH reduction [GO:0051452]; lysosome organization [GO:0007040]; monoatomic ion transmembrane transport [GO:0034220]; negative regulation of developmental pigmentation [GO:0048086]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of autophagy [GO:0010506]; regulation of exocytosis [GO:0017157]; regulation of monoatomic ion transmembrane transport [GO:0034765]; response to vitamin D [GO:0033280]; smooth muscle contraction [GO:0006939]; sodium ion transmembrane transport [GO:0035725] cytosol [GO:0005829]; endolysosome membrane [GO:0036020]; endosome membrane [GO:0010008]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome membrane [GO:0033162] "calcium channel activity [GO:0005262]; identical protein binding [GO:0042802]; intracellular phosphatidylinositol-3,5-bisphosphate-sensitive monatomic cation channel activity [GO:0097682]; ligand-gated sodium channel activity [GO:0015280]; NAADP-sensitive calcium-release channel activity [GO:0072345]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; protein kinase binding [GO:0019901]; voltage-gated calcium channel activity [GO:0005245]" 0.75027 0.31353 LFNELDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0966 0 0 0 0 Q8NHY0 B4GN2_HUMAN "Beta-1,4 N-acetylgalactosaminyltransferase 2 (EC 2.4.1.-) (Sd(a) beta-1,4-GalNAc transferase) (UDP-GalNAc:Neu5Aca2-3Galb-R b1,4-N-acetylgalactosaminyltransferase)" B4GALNT2 GALGT2 Homo sapiens (Human) lipid glycosylation [GO:0030259]; negative regulation of cell-cell adhesion [GO:0022408]; oligosaccharide biosynthetic process [GO:0009312]; protein N-linked glycosylation via asparagine [GO:0018279]; UDP-N-acetylgalactosamine metabolic process [GO:0019276]; UDP-N-acetylglucosamine metabolic process [GO:0006047] Golgi membrane [GO:0000139]; membrane [GO:0016020] acetylgalactosaminyltransferase activity [GO:0008376] 0.96833 -3.6401 LLPEERLR 11.2931 0 9.98627 0 0 0 0 9.42335 14.0953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NHY3 GA2L2_HUMAN GAS2-like protein 2 (GAS2-related protein on chromosome 17) (Growth arrest-specific protein 2-like 2) GAS2L2 GAR17 Homo sapiens (Human) actin crosslink formation [GO:0051764]; microtubule bundle formation [GO:0001578]; negative regulation of microtubule depolymerization [GO:0007026]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; protein localization to microtubule plus-end [GO:1904825]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296]; regulation of microtubule polymerization or depolymerization [GO:0031110] ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886] actin filament binding [GO:0051015]; cytoskeletal anchor activity [GO:0008093]; G-protein alpha-subunit binding [GO:0001965]; microtubule binding [GO:0008017] 0.91986 -0.90699 GAGTGASR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.69556 0 0 0 0 Q8NHY6 ZFP28_HUMAN Zinc finger protein 28 homolog (Zfp-28) (Krueppel-like zinc finger factor X6) ZFP28 KIAA1431 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96928 -7.1927 AFGDNSSCTQHQR 9.2078 0 0 0 0 0 0 0 0 0 0 11.8505 0 0 0 9.36685 9.30362 9.51546 0 10.4111 0 0 0 0 0 8.55585 0 Q8NI08 NCOA7_HUMAN Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1) NCOA7 ERAP140 ESNA1 Nbla00052 Nbla10993 Homo sapiens (Human) negative regulation of cellular response to oxidative stress [GO:1900408]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; response to oxidative stress [GO:0006979] nucleus [GO:0005634] nuclear receptor binding [GO:0016922]; nuclear receptor coactivator activity [GO:0030374] 0.84938 0.15513 SNQLKEIRR 0 8.85421 0 0 0 0 0 9.12166 0 9.00284 10.8159 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8NI27 THOC2_HUMAN THO complex subunit 2 (Tho2) (hTREX120) THOC2 CXorf3 Homo sapiens (Human) generation of neurons [GO:0048699]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; neuron development [GO:0048666]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA splicing [GO:0008380]; viral mRNA export from host cell nucleus [GO:0046784] nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; THO complex [GO:0000347]; THO complex part of transcription export complex [GO:0000445]; transcription export complex [GO:0000346] mRNA binding [GO:0003729] 0.96795 -3.8225 AQTIDRAK 0 0 0 0 0 0 10.3147 0 0 0 0 0 0 0 10.2564 0 0 0 0 0 0 0 0 0 0 9.54634 10.1558 Q8NI29 FBX27_HUMAN F-box only protein 27 (F-box/G-domain protein 5) FBXO27 FBG5 FBX27 Homo sapiens (Human) glycoprotein catabolic process [GO:0006516]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent ERAD pathway [GO:0030433] cytoplasm [GO:0005737]; cytosol [GO:0005829]; SCF ubiquitin ligase complex [GO:0019005] 0.88505 -0.23355 DHGATGR 0 0 0 0 8.53594 8.67867 12.6815 0 12.5874 13.1453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7637 0 Q8NI32 LPD6B_HUMAN Ly6/PLAUR domain-containing protein 6B LYPD6B Homo sapiens (Human) extracellular region [GO:0005576]; plasma membrane [GO:0005886] acetylcholine receptor regulator activity [GO:0030548] 0.86306 0.083407 NINFYNVRPPLDPTPFPNSFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4845 0 11.3083 0 0 0 0 0 0 0 0 Q8NI35 INADL_HUMAN InaD-like protein (Inadl protein) (hINADL) (Channel-interacting PDZ domain-containing protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) PATJ CIPP INADL Homo sapiens (Human) establishment of apical/basal cell polarity [GO:0035089]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular signal transduction [GO:0035556]; microtubule organizing center organization [GO:0031023]; regulation of microtubule cytoskeleton organization [GO:0070507]; tight junction assembly [GO:0120192] apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; centriolar satellite [GO:0034451]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] 0.56607 0.50174 DGRLQTGDHILK 9.8069 0 8.85574 0 0 0 0 0 0 0 0 0 0 0 0 9.04491 0 0 0 0 0 0 0 0 0 0 0 Q8NI51 CTCFL_HUMAN Transcriptional repressor CTCFL (Brother of the regulator of imprinted sites) (CCCTC-binding factor) (CTCF paralog) (CTCF-like protein) (Cancer/testis antigen 27) (CT27) (Zinc finger protein CTCF-T) CTCFL BORIS Homo sapiens (Human) cell cycle [GO:0007049]; establishment of protein localization to chromatin [GO:0071169]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression by genomic imprinting [GO:0006349]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription initiation-coupled chromatin remodeling [GO:0045815] chromosome [GO:0005694]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "chromatin insulator sequence binding [GO:0043035]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; histone binding [GO:0042393]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription cis-regulatory region binding [GO:0000976]" 0.94566 -1.341 CFRQKQLLNAHFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.72272 0 0 0 0 0 0 0 Q8NI77 KI18A_HUMAN Kinesin-like protein KIF18A (Marrow stromal KIF18A) (MS-KIF18A) KIF18A OK/SW-cl.108 Homo sapiens (Human) cellular response to estradiol stimulus [GO:0071392]; male meiotic nuclear division [GO:0007140]; microtubule depolymerization [GO:0007019]; microtubule-based movement [GO:0007018]; mitotic metaphase plate congression [GO:0007080]; mitotic sister chromatid segregation [GO:0000070]; protein transport [GO:0015031]; regulation of microtubule cytoskeleton organization [GO:0070507]; seminiferous tubule development [GO:0072520] caveola [GO:0005901]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinesin complex [GO:0005871]; kinetochore [GO:0000776]; kinetochore microtubule [GO:0005828]; microtubule cytoskeleton [GO:0015630]; microtubule organizing center [GO:0005815]; mitotic spindle astral microtubule [GO:0061673]; mitotic spindle midzone [GO:1990023]; nucleus [GO:0005634]; ruffle [GO:0001726] actin binding [GO:0003779]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; plus-end-directed microtubule motor activity [GO:0008574]; tubulin-dependent ATPase activity [GO:0070463] 0.92357 -1.0756 ASTSGAK 0 0 0 0 8.89224 0 0 0 0 0 0 0 10.43 0 0 0 0 10.6919 11.392 0 10.7505 10.0736 0 0 0 0 8.68881 Q8TA94 ZN563_HUMAN Zinc finger protein 563 ZNF563 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.87155 0.060905 TFHHLGSFQIHMK 0 9.04489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TAA3 PSMA8_HUMAN Proteasome subunit alpha-type 8 (Proteasome alpha 4 subunit) (Alpha4s) (Proteasome subunit alpha-type 7-like) PSMA8 PSMA7L Homo sapiens (Human) cell differentiation [GO:0030154]; meiotic cell cycle [GO:0051321]; proteasomal protein catabolic process [GO:0010498]; regulation of meiosis I [GO:0060631]; spermatogenesis [GO:0007283]; ubiquitin-dependent protein catabolic process [GO:0006511] "cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; proteasome core complex, alpha-subunit complex [GO:0019773]; spermatoproteasome complex [GO:1990111]" 0.92315 -1.1571 ALLEVVQSGGK 0 0 0 0 0 0 0 0 0 0 9.0091 0 0 9.46444 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TAA5 GRPE2_HUMAN "GrpE protein homolog 2, mitochondrial (Mt-GrpE#2)" GRPEL2 Homo sapiens (Human) intracellular protein transport [GO:0006886]; protein folding [GO:0006457]; protein import into mitochondrial matrix [GO:0030150] "mitochondrion [GO:0005739]; PAM complex, Tim23 associated import motor [GO:0001405]; TIM23 mitochondrial import inner membrane translocase complex [GO:0005744]" adenyl-nucleotide exchange factor activity [GO:0000774]; protein homodimerization activity [GO:0042803]; protein-folding chaperone binding [GO:0051087]; unfolded protein binding [GO:0051082] 0.8988 -0.62075 AIADCENIR 9.98897 0 9.33253 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5522 0 0 0 0 0 0 Q8TAC1 RFESD_HUMAN Rieske domain-containing protein RFESD Homo sapiens (Human) "2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]" 0.91378 -0.76074 NLDGSAQDPEKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4265 0 0 0 0 0 0 0 0 0 Q8TAD2 IL17D_HUMAN Interleukin-17D (IL-17D) (Interleukin-27) (IL-27) IL17D UNQ3096/PRO21175 Homo sapiens (Human) inflammatory response [GO:0006954]; negative regulation of hemopoiesis [GO:1903707]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757] extracellular space [GO:0005615] cytokine activity [GO:0005125]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018] 0.88317 -0.27342 ISYDPARYPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3781 0 0 0 0 0 0 Q8TAD4 ZNT5_HUMAN Proton-coupled zinc antiporter SLC30A5 (Solute carrier family 30 member 5) (Zinc transporter 5) (ZnT-5) (ZnT-like transporter 1) (hZTL1) SLC30A5 ZNT5 ZNTL1 ZTL1 UNQ863/PRO1879 Homo sapiens (Human) cobalt ion transport [GO:0006824]; GPI anchor biosynthetic process [GO:0006506]; insulin processing [GO:0030070]; intracellular zinc ion homeostasis [GO:0006882]; response to zinc ion [GO:0010043]; zinc ion import across plasma membrane [GO:0071578]; zinc ion import into Golgi lumen [GO:1904257]; zinc ion import into organelle [GO:0062111]; zinc ion transmembrane transport [GO:0071577]; zinc ion transport [GO:0006829] apical plasma membrane [GO:0016324]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; Golgi cis cisterna membrane [GO:1990674]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; secretory granule membrane [GO:0030667]; trans-Golgi network membrane [GO:0032588] antiporter activity [GO:0015297]; metal ion binding [GO:0046872]; zinc efflux transmembrane transporter activity [GO:0022883]; zinc ion transmembrane transporter activity [GO:0005385]; zinc:proton antiporter activity [GO:0140826] 0.90822 -0.74269 LSVDVGGAKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9009 0 0 0 0 0 0 Q8TAD7 OCC1_HUMAN Overexpressed in colon carcinoma 1 protein (OCC-1) (AGD3) OCC1 C12orf75 Homo sapiens (Human) 0.80956 0.22682 DVTEESVTEDDK 9.74831 0 0 0 0 0 0 0 9.19572 0 9.40969 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TAE8 G45IP_HUMAN "Large ribosomal subunit protein mL64 (39S ribosomal protein L59, mitochondrial) (MRP-L59) (CKII beta-associating protein) (CR6-interacting factor 1) (CRIF1) (Growth arrest and DNA damage-inducible proteins-interacting protein 1) (Papillomavirus L2-interacting nuclear protein 1) (PLINP) (PLINP-1) (p53-responsive gene 6 protein)" GADD45GIP1 MRPL59 PLINP1 PRG6 Homo sapiens (Human) cell cycle [GO:0007049]; mitochondrial translation [GO:0032543] mitochondrial inner membrane [GO:0005743]; mitochondrial large ribosomal subunit [GO:0005762]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] 0.19907 0.92313 ELEAEEREWYPSLATMQESLR 0 0 0 0 8.54392 0 0 9.83807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TAF3 WDR48_HUMAN WD repeat-containing protein 48 (USP1-associated factor 1) (WD repeat endosomal protein) (p80) WDR48 KIAA1449 UAF1 Homo sapiens (Human) DNA damage response [GO:0006974]; double-strand break repair via homologous recombination [GO:0000724]; embryonic organ development [GO:0048568]; homeostasis of number of cells [GO:0048872]; multicellular organism growth [GO:0035264]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of epithelial cell proliferation [GO:0050679]; regulation of protein monoubiquitination [GO:1902525]; seminiferous tubule development [GO:0072520]; single fertilization [GO:0007338]; skeletal system morphogenesis [GO:0048705]; skin development [GO:0043588]; spermatogenesis [GO:0007283] cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] deubiquitinase activator activity [GO:0035800]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; single-stranded DNA binding [GO:0003697]; ubiquitin binding [GO:0043130] 0.96232 -2.0341 TVKHFIWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4776 0 0 0 0 0 0 0 0 0 Q8TAF5 LQK1_HUMAN Putative uncharacterized protein LQK1 (FLVCR1 antisense RNA 1) (FLVCR1 divergent transcript) FLVCR1-DT FLVCR1-AS1 LQK1 Homo sapiens (Human) 0.91653 -0.8472 GLCCWKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.62337 0 0 0 0 Q8TAG9 EXOC6_HUMAN Exocyst complex component 6 (Exocyst complex component Sec15A) (SEC15-like protein 1) EXOC6 SEC15A SEC15L SEC15L1 Homo sapiens (Human) exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; intracellular protein transport [GO:0006886]; membrane fission [GO:0090148]; mitotic cytokinesis [GO:0000281]; vesicle docking involved in exocytosis [GO:0006904]; vesicle tethering involved in exocytosis [GO:0090522] cytosol [GO:0005829]; exocyst [GO:0000145]; Flemming body [GO:0090543]; growth cone [GO:0030426]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] 0.90142 -0.69655 SSTEIDDMLR 0 0 0 0 12.0545 0 0 0 0 0 0 0 11.5507 0 11.7446 0 0 0 0 0 0 0 0 0 0 0 0 Q8TAI1 TYMOS_HUMAN TYMS opposite strand protein TYMSOS C18orf56 Homo sapiens (Human) 0.7476 0.31563 TMRPLPR 0 10.604 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TAI7 REBL1_HUMAN GTPase RhebL1 (Ras homolog enriched in brain like-1 c) (RhebL1c) (Ras homolog enriched in brain-like protein 1) (Rheb-like protein 1) (Rheb2) RHEBL1 Homo sapiens (Human) positive regulation of NF-kappaB transcription factor activity [GO:0051092]; small GTPase mediated signal transduction [GO:0007264]; TOR signaling [GO:0031929] cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; plasma membrane [GO:0005886] GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872] 0.88369 -0.10684 VENSYGQERRCHLM 0 0 0 0 0 10.711 0 0 0 0 0 0 8.90668 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TAK5 GABP2_HUMAN GA-binding protein subunit beta-2 (GABP subunit beta-2) (GABPB-2) GABPB2 Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944] nucleus [GO:0005634] identical protein binding [GO:0042802]; transcription cis-regulatory region binding [GO:0000976] 0.88889 -0.42392 AGVSRDAR 0 0 0 9.22149 0 9.1533 0 15.9124 0 0 0 0 0 0 0 0 0 0 0 0 0 8.96576 9.30914 9.40875 0 0 0 Q8TAL5 CI043_HUMAN Uncharacterized protein C9orf43 C9orf43 Homo sapiens (Human) 0.92313 -1.1529 GHPRILGSSCK 0 0 0 0 0 0 0 0 0 10.3216 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TAL6 FIBIN_HUMAN Fin bud initiation factor homolog FIBIN PSEC0235 Homo sapiens (Human) protein kinase C signaling [GO:0070528]; response to dexamethasone [GO:0071548]; response to manganese ion [GO:0010042] endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794] protein homodimerization activity [GO:0042803] 0.95514 -1.5559 LKNDYLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.97974 0 0 0 0 0 0 0 0 0 0 0 0 Q8TAM1 BBS10_HUMAN Bardet-Biedl syndrome 10 protein BBS10 C12orf58 Homo sapiens (Human) chaperone-mediated protein complex assembly [GO:0051131]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; regulation of protein-containing complex assembly [GO:0043254]; response to stimulus [GO:0050896]; visual perception [GO:0007601] cilium [GO:0005929] ATP binding [GO:0005524]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629] 0.88368 -0.16342 HWKNCSRWK 0 0 0 0 0 0 0 0 0 0 0 9.79159 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TAM2 TTC8_HUMAN Tetratricopeptide repeat protein 8 (TPR repeat protein 8) (Bardet-Biedl syndrome 8 protein) TTC8 BBS8 Homo sapiens (Human) axon guidance [GO:0007411]; camera-type eye photoreceptor cell differentiation [GO:0060219]; cilium assembly [GO:0060271]; establishment of anatomical structure orientation [GO:0048560]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of planar polarity [GO:0001736]; fat cell differentiation [GO:0045444]; inner ear receptor cell stereocilium organization [GO:0060122]; multi-ciliated epithelial cell differentiation [GO:1903251]; multicellular organism growth [GO:0035264]; negative regulation of GTPase activity [GO:0034260]; non-motile cilium assembly [GO:1905515]; olfactory bulb development [GO:0021772]; protein localization to plasma membrane [GO:0072659]; protein transport [GO:0015031]; regulation of protein localization [GO:0032880]; regulation of stress fiber assembly [GO:0051492]; renal tubule development [GO:0061326]; sensory perception of smell [GO:0007608]; sensory processing [GO:0050893] BBSome [GO:0034464]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary membrane [GO:0060170]; cilium [GO:0005929]; cytosol [GO:0005829]; non-motile cilium [GO:0097730]; photoreceptor connecting cilium [GO:0032391] RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629] 0.95472 -1.5201 DWWWKVQIGK 0 0 0 0 0 0 0 0 0 0 0 12.4983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TAP6 CEP76_HUMAN Centrosomal protein of 76 kDa (Cep76) CEP76 C18orf9 Homo sapiens (Human) regulation of centriole replication [GO:0046599] centriole [GO:0005814]; centrosome [GO:0005813]; cytosol [GO:0005829]; protein-containing complex [GO:0032991] 0.16667 0.97433 AFATCLRSPFCEEIICCR 0 0 0 0 0 10.2905 0 0 0 0 0 0 0 0 0 16.0045 0 0 0 9.54104 0 0 0 0 0 0 0 Q8TAQ2 SMRC2_HUMAN SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2) SMARCC2 BAF170 Homo sapiens (Human) chromatin remodeling [GO:0006338]; negative regulation of DNA-templated transcription [GO:0045892]; nervous system development [GO:0007399]; nucleosome disassembly [GO:0006337]; positive regulation of cell differentiation [GO:0045597]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of T cell differentiation [GO:0045582]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357] bBAF complex [GO:0140092]; brahma complex [GO:0035060]; chromatin [GO:0000785]; kinetochore [GO:0000776]; nBAF complex [GO:0071565]; npBAF complex [GO:0071564]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; RSC-type complex [GO:0016586]; SWI/SNF complex [GO:0016514] histone binding [GO:0042393]; transcription coactivator activity [GO:0003713] 0.88463 -0.28657 AAASATR 10.2629 10.261 0 0 0 0 0 0 0 10.361 0 0 0 0 0 0 0 10.4556 9.33291 11.718 0 0 0 9.76427 0 0 0 Q8TAQ5 ZN420_HUMAN Zinc finger protein 420 ZNF420 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleoplasm [GO:0005654] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.55824 0.55052 ECGIDFSHGSQVYM 9.89083 9.75256 9.68771 0 0 0 9.57907 9.47371 9.28529 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TAS1 UHMK1_HUMAN Serine/threonine-protein kinase Kist (EC 2.7.11.1) (Kinase interacting with stathmin) (PAM COOH-terminal interactor protein 2) (P-CIP2) (U2AF homology motif kinase 1) UHMK1 KIS KIST Homo sapiens (Human) neuron projection development [GO:0031175]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of translational initiation [GO:0045948]; protein autophosphorylation [GO:0046777]; regulation of cell cycle [GO:0051726]; regulation of protein export from nucleus [GO:0046825] axon [GO:0030424]; dendrite cytoplasm [GO:0032839]; intracellular membrane-bounded organelle [GO:0043231]; neuronal ribonucleoprotein granule [GO:0071598]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; enzyme binding [GO:0019899]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; ribonucleoprotein complex binding [GO:0043021]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]; transferase activity [GO:0016740] 0.4481 0.64338 AGSGCAWGAEPPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.1499 0 0 0 0 0 0 0 0 Q8TAT2 FGFP3_HUMAN Fibroblast growth factor-binding protein 3 (FGF-BP3) (FGF-binding protein 3) (FGFBP-3) FGFBP3 C10orf13 PSEC0101 Homo sapiens (Human) cell-cell signaling [GO:0007267]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743]; positive regulation of vascular permeability [GO:0043117] collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576] fibroblast growth factor binding [GO:0017134]; growth factor binding [GO:0019838]; heparin binding [GO:0008201] 0.55785 0.55116 QVLGGLR 0 0 0 0 0 0 0 0 0 0 9.32955 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TAV0 FA76A_HUMAN Protein FAM76A FAM76A Homo sapiens (Human) nuclear speck [GO:0016607]; nucleoplasm [GO:0005654] 0.92166 -1.1326 HLSSSSRAGHQEKEQYSR 0 0 0 0 0 0 0 0 0 0 0 11.7172 0 0 0 0 9.54556 0 0 0 0 9.52184 0 8.33767 0 0 0 Q8TAV3 CP2W1_HUMAN Cytochrome P450 2W1 (EC 1.14.14.-) (CYPIIW1) CYP2W1 Homo sapiens (Human) aflatoxin metabolic process [GO:0046222]; organic acid metabolic process [GO:0006082]; phospholipid metabolic process [GO:0006644]; retinoic acid catabolic process [GO:0034653]; xenobiotic metabolic process [GO:0006805] cell surface [GO:0009986]; cytoplasm [GO:0005737]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886] "all-trans retinal binding [GO:0005503]; all-trans-retinol binding [GO:1904768]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; retinoic acid 4-hydroxylase activity [GO:0008401]; retinoic acid binding [GO:0001972]" 0.96124 -2.5603 HPDVQGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.03329 0 0 0 0 0 0 0 0 0 0 0 Q8TAV4 STML3_HUMAN Stomatin-like protein 3 (SLP-3) STOML3 Homo sapiens (Human) signal transduction [GO:0007165] cilium [GO:0005929]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; plasma membrane [GO:0005886] 0.91508 -0.76311 VLAAEGEMNASKSLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.99342 0 0 0 0 0 Q8TAW3 ZN671_HUMAN Zinc finger protein 671 ZNF671 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.94674 -1.3496 AFSQSSHLNVHWR 0 0 0 0 0 0 0 8.83611 0 0 0 8.87157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TAX9 GSDMB_HUMAN "Gasdermin-B (Gasdermin-like protein) [Cleaved into: Gasdermin-B, N-terminal (GSDMB-NT) (p30); Gasdermin-B, C-terminal (GSDMB-CT) (p16)]" GSDMB GSDML PP4052 PRO2521 Homo sapiens (Human) cytotoxic T cell pyroptotic process [GO:1902483]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; granzyme-mediated programmed cell death signaling pathway [GO:0140507]; killing by host of symbiont cells [GO:0051873]; killing of cells of another organism [GO:0031640]; pyroptosis [GO:0070269] cytoplasm [GO:0005737]; plasma membrane [GO:0005886] "cardiolipin binding [GO:1901612]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylserine binding [GO:0001786]; phospholipid binding [GO:0005543]; wide pore channel activity [GO:0022829]" 0.96537 -2.7093 DVLNSLAKCLGK 0 0 0 0 10.4609 10.0937 0 0 13.1865 0 0 11.3124 11.9827 0 0 0 0 0 0 0 0 0 0 0 11.2096 0 0 Q8TAY7 F110D_HUMAN Protein FAM110D FAM110D GRRP1 Homo sapiens (Human) 0.96074 -2.0125 AKYVKTHQVIAR 0 0 11.2856 9.15307 10.052 9.9454 0 11.3017 0 11.1083 10.8175 0 0 10.2986 0 0 0 0 0 0 0 9.59783 0 0 0 0 0 Q8TB03 CX038_HUMAN Uncharacterized protein CXorf38 CXorf38 Homo sapiens (Human) 0.95268 -1.4552 NGLTEDMQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5147 0 Q8TB24 RIN3_HUMAN Ras and Rab interactor 3 (Ras interaction/interference protein 3) RIN3 Homo sapiens (Human) endocytosis [GO:0006897]; negative regulation of mast cell chemotaxis [GO:0060755]; negative regulation of receptor internalization [GO:0002091]; regulation of vesicle size [GO:0097494]; signal transduction [GO:0007165] axon [GO:0030424]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; neuronal cell body [GO:0043025]; vesicle [GO:0031982] GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; small GTPase binding [GO:0031267] 0.11712 1.0948 LCLPANPK 0 0 12.9966 11.0723 0 0 12.6389 12.7585 0 12.3181 11.9121 0 11.8298 0 11.8855 10.2495 12.0069 0 0 0 0 0 0 0 0 0 0 Q8TB37 NUBPL_HUMAN Iron-sulfur protein NUBPL (IND1 homolog) (Nucleotide-binding protein-like) (huInd1) NUBPL C14orf127 Homo sapiens (Human) iron-sulfur cluster assembly [GO:0016226]; mitochondrial respiratory chain complex I assembly [GO:0032981]; mitochondrion morphogenesis [GO:0070584] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886] "4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; ATP-dependent FeS chaperone activity [GO:0140663]; metal ion binding [GO:0046872]" 0.20031 0.92098 AGGGATAPLGGSR 0 0 0 0 0 0 9.14929 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.9367 0 0 Q8TB45 DPTOR_HUMAN DEP domain-containing mTOR-interacting protein (DEP domain-containing protein 6) DEPTOR DEPDC6 Homo sapiens (Human) intracellular signal transduction [GO:0035556]; negative regulation of cell size [GO:0045792]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of TOR signaling [GO:0032007]; negative regulation of TORC1 signaling [GO:1904262]; negative regulation of TORC2 signaling [GO:1903940]; regulation of extrinsic apoptotic signaling pathway [GO:2001236] 0.96867 -3.9285 LFYRFRK 11.7829 0 0 0 0 0 8.84881 0 0 0 0 0 0 0 0 10.0086 0 0 0 0 0 0 0 0 0 0 0 Q8TB52 FBX30_HUMAN F-box only protein 30 FBXO30 FBX30 Homo sapiens (Human) protein ubiquitination [GO:0016567] cytosol [GO:0005829] ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.87402 0.036093 DVCGSLLQSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7.92908 0 0 0 0 0 0 0 0 0 Q8TB69 ZN519_HUMAN Zinc finger protein 519 ZNF519 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96209 -2.6097 IHTGEKSFKCEECGK 0 0 0 0 11.9552 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TB72 PUM2_HUMAN Pumilio homolog 2 (Pumilio-2) PUM2 KIAA0235 PUMH2 Homo sapiens (Human) adipose tissue development [GO:0060612]; chromosome organization [GO:0051276]; hair follicle development [GO:0001942]; miRNA processing [GO:0035196]; mitochondrion organization [GO:0007005]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of chromosome segregation [GO:0051983]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of mRNA stability [GO:0043488]; regulation of translation [GO:0006417]; respiratory electron transport chain [GO:0022904]; skeletal system development [GO:0001501]; stress granule assembly [GO:0034063] cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471] lncRNA binding [GO:0106222]; miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; pumilio-response element binding [GO:0062104]; RNA binding [GO:0003723] 0.87084 0.043674 QASPTEVVER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.03993 0 0 Q8TB73 NDNF_HUMAN Protein NDNF (Neuron-derived neurotrophic factor) NDNF C4orf31 UNQ2748/PRO6487 Homo sapiens (Human) angiogenesis [GO:0001525]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to hypoxia [GO:0071456]; extracellular matrix organization [GO:0030198]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of neuron apoptotic process [GO:0043524]; neuron migration [GO:0001764]; nitric oxide mediated signal transduction [GO:0007263]; peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan [GO:0019800]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of neuron projection development [GO:0010976]; response to ischemia [GO:0002931]; vascular wound healing [GO:0061042] extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201] 0.96808 -2.7561 EQNQCLGPDIRK 12.6469 12.7339 13.2162 9.63365 9.21371 10.0922 0 12.8408 12.7098 13.4685 13.643 0 0 0 0 0 12.0463 11.6696 10.4368 0 0 0 0 0 0 0 0 Q8TBB0 THAP6_HUMAN THAP domain-containing protein 6 THAP6 Homo sapiens (Human) microtubule cytoskeleton [GO:0015630] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.88937 -0.44208 HKLDHVIGELEDTK 0 0 0 0 0 0 9.52511 9.52468 0 10.8162 10.7989 10.6043 11.0283 11.278 11.2029 11.9331 0 0 10.8518 0 0 0 10.8125 0 0 0 0 Q8TBB1 LNX1_HUMAN E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb-protein X 1) (Numb-binding protein 1) (PDZ domain-containing RING finger protein 2) (RING-type E3 ubiquitin transferase LNX) LNX1 LNX PDZRN2 UNQ574/PRO1136 Homo sapiens (Human) protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737] identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165]; ubiquitin-protein transferase activity [GO:0004842] 0.92268 -0.9417 DPGESLGMTVAGGASHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3668 0 0 0 0 0 0 0 0 0 Q8TBE3 FNDC9_HUMAN Fibronectin type III domain-containing protein 9 FNDC9 C5orf40 Homo sapiens (Human) membrane [GO:0016020] 0.80771 0.2307 AGHMEEANGLVR 0 0 0 0 0 0 0 0 0 0 0 0 0 8.95294 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TBF2 PXL2B_HUMAN Prostamide/prostaglandin F synthase (Prostamide/PG F synthase) (Prostamide/PGF synthase) (EC 1.11.1.20) (Peroxiredoxin-like 2B) (Protein FAM213B) PRXL2B C1orf93 FAM213B Homo sapiens (Human) prostaglandin biosynthetic process [GO:0001516] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; myelin sheath [GO:0043209] "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; prostaglandin-F synthase activity [GO:0047017]" 0.51154 0.60368 STVDLAR 0 0 0 0 0 0 0 0 0 0 10.2005 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TBF5 PIGX_HUMAN Phosphatidylinositol-glycan biosynthesis class X protein (PIG-X) PIGX Homo sapiens (Human) GPI anchor biosynthetic process [GO:0006506] endoplasmic reticulum membrane [GO:0005789] 0.8838 -0.27854 QEVLKDGFHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.76398 0 0 0 0 0 0 0 Q8TBF8 FA81A_HUMAN Protein FAM81A FAM81A Homo sapiens (Human) "glutamatergic synapse [GO:0098978]; postsynaptic density, intracellular component [GO:0099092]" 0.88522 -0.29545 VARCDASIAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3975 0 0 0 0 Q8TBG4 AT2L1_HUMAN Ethanolamine-phosphate phospho-lyase (EC 4.2.3.2) (Alanine--glyoxylate aminotransferase 2-like 1) ETNPPL AGXT2L1 Homo sapiens (Human) mitochondrial matrix [GO:0005759] ethanolamine-phosphate phospho-lyase activity [GO:0050459]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483] 0.88904 -0.44322 EFVHVAPTPDTYRGKYR 0 12.5309 12.351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TBH0 ARRD2_HUMAN Arrestin domain-containing protein 2 ARRDC2 PP2703 Homo sapiens (Human) protein transport [GO:0015031] cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; plasma membrane [GO:0005886] 0.80332 0.23854 VLHVDYALK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4196 0 0 0 0 0 0 0 0 0 0 Q8TBJ5 FEZF2_HUMAN Fez family zinc finger protein 2 (Forebrain embryonic zinc finger-like protein 2) (Zinc finger protein 312) (Zinc finger protein Fez-like) FEZF2 FEZL ZNF312 FKSG36 Homo sapiens (Human) axonal fasciculation [GO:0007413]; cell dedifferentiation [GO:0043697]; cerebral cortex GABAergic interneuron migration [GO:0021853]; commitment of neuronal cell to specific neuron type in forebrain [GO:0021902]; dendrite development [GO:0016358]; dentate gyrus development [GO:0021542]; forebrain anterior/posterior pattern specification [GO:0021797]; locomotory behavior [GO:0007626]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; neuron fate determination [GO:0048664]; positive regulation of neuron differentiation [GO:0045666]; regulation of axon guidance [GO:1902667]; regulation of neurogenesis [GO:0050767] nucleus [GO:0005634] "chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.92325 -1.0769 LAGLAADK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.62589 0 0 0 0 0 10.5469 0 0 9.60357 0 0 0 Q8TBK2 SETD6_HUMAN N-lysine methyltransferase SETD6 (EC 2.1.1.-) (SET domain-containing protein 6) SETD6 Homo sapiens (Human) negative regulation of NF-kappaB transcription factor activity [GO:0032088]; peptidyl-lysine monomethylation [GO:0018026]; regulation of inflammatory response [GO:0050727]; stem cell differentiation [GO:0048863]; stem cell population maintenance [GO:0019827] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] NF-kappaB binding [GO:0051059]; protein-lysine N-methyltransferase activity [GO:0016279]; S-adenosyl-L-methionine binding [GO:1904047] 0.92185 -1.1339 EVYAKLSWR 0 10.3661 10.3308 0 0 0 0 0 10.1993 0 0 0 0 0 0 0 0 0 0 9.39397 0 0 0 0 0 0 0 Q8TBK6 ZCH10_HUMAN Zinc finger CCHC domain-containing protein 10 ZCCHC10 Homo sapiens (Human) nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270] 0.87952 0.016971 QAFDTELQPVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.21544 0 0 Q8TBM8 DJB14_HUMAN DnaJ homolog subfamily B member 14 DNAJB14 UNQ9427/PRO34683 Homo sapiens (Human) cellular response to misfolded protein [GO:0071218]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein-containing complex assembly [GO:0065003] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; nuclear membrane [GO:0031965] Hsp70 protein binding [GO:0030544] 0.92198 -1.1085 ADALSMDNCK 11.9835 0 0 0 0 0 0 0 0 9.62886 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TBP0 TBC16_HUMAN TBC1 domain family member 16 TBC1D16 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; regulation of receptor recycling [GO:0001919] cytosol [GO:0005829]; early endosome [GO:0005769] GTPase activator activity [GO:0005096] 0.86938 0.046819 EGKKGPK 0 13.5383 13.6109 0 0 0 0 0 13.6417 0 0 9.58101 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TBR7 TLC3A_HUMAN TLC domain-containing protein 3A (Protein CT120) (Protein FAM57A) TLCD3A FAM57A Homo sapiens (Human) lipid homeostasis [GO:0055088] endoplasmic reticulum [GO:0005783]; plasma membrane [GO:0005886] 0.87067 0.05013 ILLFPFMYWSYGR 0 0 0 0 0 0 0 0 0 0 0 12.0799 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TBY0 RBM46_HUMAN Probable RNA-binding protein 46 (Cancer/testis antigen 68) (CT68) (RNA-binding motif protein 46) RBM46 Homo sapiens (Human) mRNA stabilization [GO:0048255]; trophectodermal cell differentiation [GO:0001829] nucleus [GO:0005634] mRNA binding [GO:0003729] 0.92105 -1.1054 LMMEFSGENR 0 0 0 0 9.24693 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TBY8 PMFBP_HUMAN Polyamine-modulated factor 1-binding protein 1 (PMF-1-binding protein) PMFBP1 Homo sapiens (Human) spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; sperm connecting piece [GO:0097224] 0.96196 -2.0382 KLEEENENLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0063 9.39556 0 8.47358 0 0 0 9.34125 9.29914 0 0 11.0612 9.86065 Q8TBZ0 CC110_HUMAN Coiled-coil domain-containing protein 110 (Cancer/testis antigen 52) (CT52) (Cancer/testis antigen KM-HN-1) CCDC110 KMHN1 Homo sapiens (Human) cytoskeleton [GO:0005856]; cytosol [GO:0005829]; nucleoplasm [GO:0005654] 0.96937 -3.4114 ISELEALVK 11.7231 0 0 0 0 9.96177 0 9.4453 0 0 0 0 0 8.2937 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TBZ2 MYBPP_HUMAN MYCBP-associated protein (AMAM-1) (AMY-1-binding protein 1) (AMAP-1) MYCBPAP AMAP1 Homo sapiens (Human) cell differentiation [GO:0030154]; chemical synaptic transmission [GO:0007268]; endocytosis [GO:0006897]; spermatogenesis [GO:0007283] clathrin vesicle coat [GO:0030125]; cytoplasm [GO:0005737]; endosome [GO:0005768]; plasma membrane [GO:0005886]; synapse [GO:0045202] clathrin binding [GO:0030276]; phospholipid binding [GO:0005543] 0.88516 -0.23003 AEEARPGDK 0 0 0 0 0 0 0 16.5293 0 0 0 0 0 0 0 11.6973 0 0 10.0727 0 0 0 0 0 0 10.2572 0 Q8TBZ3 WDR20_HUMAN WD repeat-containing protein 20 (Protein DMR) WDR20 Homo sapiens (Human) nucleoplasm [GO:0005654] 0.62871 0.40219 AADLSKPIDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.87075 0 0 0 0 10.3351 Q8TBZ5 ZN502_HUMAN Zinc finger protein 502 ZNF502 Homo sapiens (Human) positive regulation by host of viral process [GO:0044794]; regulation of DNA-templated transcription [GO:0006355]; viral release from host cell [GO:0019076] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.92303 -1.0786 IDSSGIVVK 0 0 0 0 0 0 0 8.45088 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TBZ8 ZN564_HUMAN Zinc finger protein 564 ZNF564 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.86633 0.073815 AFISFTNFQSHMIR 9.43237 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TBZ9 TEX47_HUMAN Testis-expressed protein 47 TEX47 C7orf62 Homo sapiens (Human) 0.41896 0.67951 VLLDYIGHVK 0 0 11.5174 0 0 0 0 11.4082 0 0 10.5271 0 0 0 9.97398 0 0 0 0 0 0 0 0 0 0 0 0 Q8TC05 MDM1_HUMAN Nuclear protein MDM1 MDM1 Homo sapiens (Human) negative regulation of centriole replication [GO:0046600]; retina development in camera-type eye [GO:0060041] centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; cytosol [GO:0005829]; microtubule [GO:0005874]; nucleus [GO:0005634] microtubule binding [GO:0008017] 0.96289 -2.1546 LSEISARSAASSLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4501 0 10.2982 0 0 0 0 0 Q8TC07 TBC15_HUMAN TBC1 domain family member 15 (GTPase-activating protein RAB7) (GAP for RAB7) (Rab7-GAP) TBC1D15 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; regulation of GTPase activity [GO:0043087] cytoplasm [GO:0005737]; extracellular region [GO:0005576] GTPase activator activity [GO:0005096] 0.89862 -0.6235 EERTQLQKQK 0 0 0 8.70705 0 0 0 0 0 11.4872 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TC12 RDH11_HUMAN Retinol dehydrogenase 11 (EC 1.1.1.300) (Androgen-regulated short-chain dehydrogenase/reductase 1) (HCV core-binding protein HCBP12) (Prostate short-chain dehydrogenase/reductase 1) (Retinal reductase 1) (RalR1) (Short chain dehydrogenase/reductase family 7C member 1) RDH11 ARSDR1 PSDR1 SDR7C1 CGI-82 Homo sapiens (Human) adaptation of rhodopsin mediated signaling [GO:0016062]; cellular detoxification of aldehyde [GO:0110095]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; visual perception [GO:0007601] endoplasmic reticulum membrane [GO:0005789]; photoreceptor inner segment [GO:0001917] "11-cis-retinol dehydrogenase activity [GO:0102354]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; NAD-retinol dehydrogenase activity [GO:0004745]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]" 0.85505 0.10457 WMWWLFSFFIK 0 14.7573 0 0 14.206 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TC20 CAGE1_HUMAN Cancer-associated gene 1 protein (CAGE-1) (Cancer/testis antigen 3) (CT3) CAGE1 CTAG3 Homo sapiens (Human) 0.96015 -1.7982 ATASALDLLK 0 0 16.7437 15.4655 0 0 17.1793 0 0 0 0 0 0 14.6342 15.6115 15.0963 15.2299 15.1341 0 0 0 0 0 0 0 0 0 Q8TC21 ZN596_HUMAN Zinc finger protein 596 ZNF596 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.75702 0.30062 AQICHLCGK 0 16.0002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TC27 ADA32_HUMAN Disintegrin and metalloproteinase domain-containing protein 32 (ADAM 32) ADAM32 UNQ5982/PRO21340 Homo sapiens (Human) binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; male gonad development [GO:0008584]; proteolysis [GO:0006508] plasma membrane [GO:0005886] metalloendopeptidase activity [GO:0004222] 0.92005 -0.90747 DRNNKYVFCGWR 0 0 0 0 0 0 0 0 8.71459 0 9.07668 8.77281 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TC29 ENKUR_HUMAN Enkurin ENKUR C10orf63 Homo sapiens (Human) establishment of left/right asymmetry [GO:0061966]; flagellated sperm motility [GO:0030317] 9+0 motile cilium [GO:0097728]; 9+2 motile cilium [GO:0097729]; acrosomal vesicle [GO:0001669]; axonemal microtubule [GO:0005879]; sperm principal piece [GO:0097228] calmodulin binding [GO:0005516]; SH3 domain binding [GO:0017124] 0.94784 -1.3605 NWEEVHK 10.4021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TC41 RN217_HUMAN E3 ubiquitin-protein ligase RNF217 (EC 2.3.2.31) (IBR domain-containing protein 1) (Opposite STL) (RING finger protein 217) RNF217 C6orf172 IBRDC1 OSTL Homo sapiens (Human) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; ubiquitin ligase complex [GO:0000151] metal ion binding [GO:0046872]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.87701 -0.0039013 YLPERPHLR 10.1319 10.5581 10.4273 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TC44 POC1B_HUMAN POC1 centriolar protein homolog B (Pix1) (Proteome of centriole protein 1B) (WD repeat-containing protein 51B) POC1B WDR51B Homo sapiens (Human) cell population proliferation [GO:0008283]; centriole replication [GO:0007099]; cilium assembly [GO:0060271]; retina homeostasis [GO:0001895] centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; spindle pole [GO:0000922] 0.9617 -2.042 AYRYVGHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5623 Q8TC56 GAR3_HUMAN Golgi-associated RAB2 interactor protein 3 GARIN3 FAM71B HSD-51 HSD51 Homo sapiens (Human) Cajal body [GO:0015030]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634] 0.9649 -2.3793 EDLFCYWEK 0 0 0 0 9.22824 0 0 0 0 10.5098 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.76271 0 Q8TC57 M1AP_HUMAN Meiosis 1 arrest protein (Meiosis 1-arresting protein) (Meiosis 1-associated protein) (Spermatogenesis-associated protein 37) M1AP C2orf65 SPATA37 Homo sapiens (Human) cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; female gamete generation [GO:0007292]; male meiosis chromosome separation [GO:0051308]; meiosis I [GO:0007127]; RNA processing [GO:0006396]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; membrane [GO:0016020] identical protein binding [GO:0042802] 0.95926 -1.95 ATVAPLPMTPVPGRASK 8.70335 0 8.77643 0 9.981 0 0 0 0 0 10.4589 11.8732 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TC59 PIWL2_HUMAN Piwi-like protein 2 (EC 3.1.26.-) (Cancer/testis antigen 80) (CT80) PIWIL2 HILI Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; germ-line stem cell population maintenance [GO:0030718]; meiotic cell cycle [GO:0051321]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of transposition [GO:0010529]; oogenesis [GO:0048477]; positive regulation of meiosis I [GO:0060903]; positive regulation of translation [GO:0045727]; rhythmic process [GO:0048511]; RNA-mediated gene silencing [GO:0031047]; secondary piRNA processing [GO:0140965]; spermatogenesis [GO:0007283] chromatoid body [GO:0033391]; cytoplasm [GO:0005737]; dense body [GO:0097433]; nucleus [GO:0005634]; P granule [GO:0043186]; perinucleolar chromocenter [GO:0010370]; PET complex [GO:1990923]; pi-body [GO:0071546] metal ion binding [GO:0046872]; mRNA binding [GO:0003729]; piRNA binding [GO:0034584]; polysome binding [GO:1905538]; RNA endonuclease activity [GO:0004521] 0.88329 -0.058525 EITFLEYYSK 0 0 0 0 9.53545 0 0 0 0 0 9.03009 0 0 0 0 0 0 0 0 0 0 0 0 10.5783 0 0 0 Q8TC84 FANK1_HUMAN Fibronectin type 3 and ankyrin repeat domains protein 1 FANK1 HSD13 UNQ6504/PRO21382 Homo sapiens (Human) negative regulation of apoptotic process [GO:0043066]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of apoptotic process [GO:0042981] ciliary basal body [GO:0036064]; ciliary base [GO:0097546]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.56323 0.51055 MHTYGIIYTGYATK 9.51722 9.75487 9.59552 9.21735 9.56199 0 0 9.54655 0 10.972 11.2471 0 0 12.6151 0 0 0 0 0 0 0 0 0 0 9.68795 0 0 Q8TC90 CCER1_HUMAN Coiled-coil domain-containing glutamate-rich protein 1 CCER1 C12orf12 Homo sapiens (Human) 0.56349 0.489 LYEWREPGMR 0 0 0 0 9.08648 8.96119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TC92 ENOX1_HUMAN Ecto-NOX disulfide-thiol exchanger 1 (Candidate growth-related and time keeping constitutive hydroquinone [NADH] oxidase) (cCNOX) (Cell proliferation-inducing gene 38 protein) (Constitutive Ecto-NOX) (cNOX) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)] ENOX1 PIG38 Homo sapiens (Human) ultradian rhythm [GO:0007624] external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] NADH dehydrogenase activity [GO:0003954]; protein disulfide isomerase activity [GO:0003756]; RNA binding [GO:0003723] 0.43424 0.65421 LGSSTDK 0 0 0 0 9.05507 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TC99 FNDC8_HUMAN Fibronectin type III domain-containing protein 8 FNDC8 Homo sapiens (Human) nucleus [GO:0005634] 0.83614 0.18819 LSFSPMAK 10.5952 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TCA0 LRC20_HUMAN Leucine-rich repeat-containing protein 20 LRRC20 UNQ2429/PRO4989 Homo sapiens (Human) 0.95497 -1.5771 LPSEVSALQHLKAIDLSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.6779 0 0 0 0 0 0 0 0 0 Q8TCB7 METL6_HUMAN tRNA N(3)-methylcytidine methyltransferase METTL6 (EC 2.1.1.-) (Methyltransferase-like protein 6) (hMETTL6) METTL6 Homo sapiens (Human) tRNA methylation [GO:0030488]; tRNA modification [GO:0006400] cytoplasm [GO:0005737]; nucleus [GO:0005634] enzyme binding [GO:0019899]; tRNA (cytosine-3-)-methyltransferase activity [GO:0052735] 0.9007 -0.69307 LGENFYVR 15.7228 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TCC3 RM30_HUMAN "Large ribosomal subunit protein uL30m (39S ribosomal protein L28, mitochondrial) (L28mt) (MRP-L28) (39S ribosomal protein L30, mitochondrial) (L30mt) (MRP-L30)" MRPL30 MRPL28 RPML28 HSPC249 Homo sapiens (Human) mitochondrial translation [GO:0032543] mitochondrial inner membrane [GO:0005743]; mitochondrial large ribosomal subunit [GO:0005762]; mitochondrion [GO:0005739] structural constituent of ribosome [GO:0003735] 0.91561 -0.77645 MAGILRLVVQWPPGR 0 0 0 9.97885 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TCC7 S22A8_HUMAN Organic anion transporter 3 (hOAT3) (Organic anion/dicarboxylate exchanger) (Solute carrier family 22 member 8) SLC22A8 OAT3 Homo sapiens (Human) monoatomic ion transport [GO:0006811]; prostaglandin transport [GO:0015732]; response to toxic substance [GO:0009636]; transport across blood-brain barrier [GO:0150104] apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] organic anion transmembrane transporter activity [GO:0008514]; prostaglandin transmembrane transporter activity [GO:0015132]; solute:inorganic anion antiporter activity [GO:0005452] 0.76079 0.29175 VAVFNGK 0 0 0 0 0 0 0 0 0 13.4685 13.643 13.5563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TCD5 NT5C_HUMAN "5'(3')-deoxyribonucleotidase, cytosolic type (EC 3.1.3.-) (Cytosolic 5',3'-pyrimidine nucleotidase) (Deoxy-5'-nucleotidase 1) (dNT-1)" NT5C DNT1 UMPH2 Homo sapiens (Human) allantoin metabolic process [GO:0000255]; amide catabolic process [GO:0043605]; dCMP catabolic process [GO:0006249]; dephosphorylation [GO:0016311]; dGMP catabolic process [GO:0046055]; dTMP catabolic process [GO:0046074]; dUMP catabolic process [GO:0046079]; IMP catabolic process [GO:0006204]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223]; UMP catabolic process [GO:0046050] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634] 5'-nucleotidase activity [GO:0008253]; identical protein binding [GO:0042802]; IMP 5'-nucleotidase activity [GO:0050483]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; pyrimidine nucleotide binding [GO:0019103] 0.89771 -0.58238 LLSWSDNWREILDSK 10.2536 0 10.1867 0 0 0 0 11.4604 11.245 11.4033 0 0 0 0 0 0 11.4638 0 0 0 0 0 10.4802 10.4996 12.4678 0 0 Q8TCG1 CIP2A_HUMAN Protein CIP2A (Cancerous inhibitor of PP2A) (p90 autoantigen) CIP2A KIAA1524 Homo sapiens (Human) cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886] cadherin binding [GO:0045296]; protein homodimerization activity [GO:0042803] 0.96311 -2.1618 DLQITCDSLNK 0 0 0 0 0 9.06264 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1046 0 0 0 Q8TCG2 P4K2B_HUMAN Phosphatidylinositol 4-kinase type 2-beta (EC 2.7.1.67) (Phosphatidylinositol 4-kinase type II-beta) (PI4KII-BETA) PI4K2B Homo sapiens (Human) endosome organization [GO:0007032]; Golgi organization [GO:0007030]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol phosphate biosynthetic process [GO:0046854] cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802] 1-phosphatidylinositol 4-kinase activity [GO:0004430]; ATP binding [GO:0005524] 0.95146 -1.4409 CEKEIDHKESK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1826 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TCJ0 FBX25_HUMAN F-box only protein 25 FBXO25 FBX25 Homo sapiens (Human) protein ubiquitination [GO:0016567] cytoplasm [GO:0005737]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; ubiquitin ligase complex [GO:0000151] actin binding [GO:0003779]; ubiquitin-protein transferase activity [GO:0004842] 0.88072 0.0060262 VLDDHHNPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.10573 0 0 0 0 0 0 0 0 Q8TCJ2 STT3B_HUMAN Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (Oligosaccharyl transferase subunit STT3B) (STT3-B) (EC 2.4.99.18) (Source of immunodominant MHC-associated peptides homolog) STT3B SIMP Homo sapiens (Human) co-translational protein modification [GO:0043686]; glycoprotein catabolic process [GO:0006516]; post-translational protein modification [GO:0043687]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]; response to unfolded protein [GO:0006986]; ubiquitin-dependent ERAD pathway [GO:0030433] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; oligosaccharyltransferase complex [GO:0008250]; oligosaccharyltransferase I complex [GO:0034998]; protein-containing complex [GO:0032991] dolichyl-diphosphooligosaccharide-protein glycotransferase activity [GO:0004579]; metal ion binding [GO:0046872] 0.96912 -4.2368 EAYFWLR 0 0 0 9.49045 0 0 0 0 0 0 9.18992 0 0 0 0 0 0 0 0 8.55777 0 8.87949 0 0 0 0 0 Q8TCN5 ZN507_HUMAN Zinc finger protein 507 ZNF507 KIAA1084 Homo sapiens (Human) regulation of gene expression [GO:0010468] nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.92385 -0.99668 LRERTDQNASDDDILK 11.8939 12.2592 11.8554 11.329 0 11.3633 11.2082 11.225 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0109 0 0 0 0 0 Q8TCP9 F200A_HUMAN Protein FAM200A FAM200A C7orf38 Homo sapiens (Human) membrane [GO:0016020] 0.86396 0.076701 VEEEDEEDHFQK 0 0 0 0 0 0 9.91737 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TCS8 PNPT1_HUMAN "Polyribonucleotide nucleotidyltransferase 1, mitochondrial (EC 2.7.7.8) (3'-5' RNA exonuclease OLD35) (PNPase old-35) (Polynucleotide phosphorylase 1) (PNPase 1) (Polynucleotide phosphorylase-like protein)" PNPT1 PNPASE Homo sapiens (Human) cellular response to interferon-beta [GO:0035458]; cellular response to oxidative stress [GO:0034599]; liver regeneration [GO:0097421]; mitochondrial mRNA catabolic process [GO:0000958]; mitochondrial mRNA polyadenylation [GO:0097222]; mitochondrial RNA 3'-end processing [GO:0000965]; mitochondrial RNA 5'-end processing [GO:0000964]; mitochondrial RNA catabolic process [GO:0000957]; mitochondrion morphogenesis [GO:0070584]; mRNA catabolic process [GO:0006402]; negative regulation of growth [GO:0045926]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; positive regulation of miRNA catabolic process [GO:2000627]; positive regulation of mitochondrial RNA catabolic process [GO:0000962]; positive regulation of mRNA catabolic process [GO:0061014]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; regulation of cell cycle [GO:0051726]; regulation of cellular respiration [GO:0043457]; regulation of cellular senescence [GO:2000772]; response to cAMP [GO:0051591]; response to growth hormone [GO:0060416]; RNA catabolic process [GO:0006401]; RNA import into mitochondrion [GO:0035927]; RNA polyadenylation [GO:0043631]; rRNA import into mitochondrion [GO:0035928] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrial degradosome [GO:0045025]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; polysomal ribosome [GO:0042788] 3'-5'-RNA exonuclease activity [GO:0000175]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; poly(G) binding [GO:0034046]; poly(U) RNA binding [GO:0008266]; polyribonucleotide nucleotidyltransferase activity [GO:0004654]; RNA binding [GO:0003723] 0.47809 0.62532 AVAVDLGNRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.69493 0 0 0 0 Q8TCT0 CERK1_HUMAN Ceramide kinase (hCERK) (EC 2.7.1.138) (Acylsphingosine kinase) (Lipid kinase 4) (LK4) CERK KIAA1646 Homo sapiens (Human) ceramide metabolic process [GO:0006672]; glycosphingolipid metabolic process [GO:0006687]; phosphorylation [GO:0016310] cytoplasm [GO:0005737]; membrane [GO:0016020]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; ceramide kinase activity [GO:0001729]; dihydroceramide kinase activity [GO:0102773]; magnesium ion binding [GO:0000287] 0.84947 0.16293 AVLVPSSLR 0 0 0 0 0 9.11009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TCT9 HM13_HUMAN Minor histocompatibility antigen H13 (EC 3.4.23.-) (Intramembrane protease 1) (IMP-1) (IMPAS-1) (hIMP1) (Presenilin-like protein 3) (Signal peptide peptidase) HM13 H13 IMP1 PSL3 SPP MSTP086 Homo sapiens (Human) "in utero embryonic development [GO:0001701]; membrane protein proteolysis [GO:0033619]; membrane protein proteolysis involved in retrograde protein transport, ER to cytosol [GO:1904211]; regulation of heme oxygenase activity [GO:0061960]; signal peptide processing [GO:0006465]" cell surface [GO:0009986]; cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; lumenal side of endoplasmic reticulum membrane [GO:0098553]; membrane [GO:0016020]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791] "aspartic endopeptidase activity, intramembrane cleaving [GO:0042500]; peptidase activity [GO:0008233]; protein homodimerization activity [GO:0042803]; ubiquitin protein ligase binding [GO:0031625]" 0.060729 1.3325 FFPASFPNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.28977 9.2107 9.41272 0 9.65739 10.9875 0 9.87381 Q8TCU4 ALMS1_HUMAN Centrosome-associated protein ALMS1 (Alstrom syndrome protein 1) ALMS1 KIAA0328 Homo sapiens (Human) endosomal transport [GO:0016197]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of centriole replication [GO:0046599]; regulation of stress fiber assembly [GO:0051492] centrosome [GO:0005813]; cilium [GO:0005929]; cytosol [GO:0005829]; spindle pole [GO:0000922] microtubule binding [GO:0008017] 0.90845 -0.74283 NLLQCESSLNHAK 0 8.75312 0 0 0 0 0 9.32522 0 0 0 0 0 0 0 0 0 0 0 9.75559 0 0 0 0 0 0 0 Q8TCU5 NMD3A_HUMAN "Glutamate receptor ionotropic, NMDA 3A (GluN3A) (N-methyl-D-aspartate receptor subtype 3A) (NMDAR3A) (NR3A) (NMDAR-L)" GRIN3A KIAA1973 Homo sapiens (Human) "calcium ion transport [GO:0006816]; dendrite development [GO:0016358]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of dendritic spine development [GO:0061000]; prepulse inhibition [GO:0060134]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; response to ethanol [GO:0045471]; rhythmic process [GO:0048511]; synaptic transmission, glutamatergic [GO:0035249]" endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; NMDA selective glutamate receptor complex [GO:0017146]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; presynapse [GO:0098793]; synapse [GO:0045202] calcium channel activity [GO:0005262]; glutamate receptor activity [GO:0008066]; glycine binding [GO:0016594]; identical protein binding [GO:0042802]; neurotransmitter binding [GO:0042165]; NMDA glutamate receptor activity [GO:0004972]; protein phosphatase 2A binding [GO:0051721]; transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315] 0.95561 -1.5394 AGAQRDEPEPGTR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1501 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TCU6 PREX1_HUMAN "Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1) (PtdIns(3,4,5)-dependent Rac exchanger 1)" PREX1 KIAA1415 Homo sapiens (Human) actin filament polymerization [GO:0030041]; G protein-coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; neutrophil activation [GO:0042119]; neutrophil chemotaxis [GO:0030593]; positive regulation of GTPase activity [GO:0043547]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of signaling [GO:0023051]; regulation of small GTPase mediated signal transduction [GO:0051056]; superoxide metabolic process [GO:0006801]; T cell differentiation [GO:0030217] cytosol [GO:0005829]; plasma membrane [GO:0005886] enzyme binding [GO:0019899]; GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; phospholipid binding [GO:0005543] 0.96864 -7.8437 FHADEEMEGTSSK 10.6181 0 0 9.5806 0 0 11.2891 11.7243 10.5988 0 10.0454 11.3818 0 0 9.50331 0 11.6561 10.9003 0 0 0 0 0 0 9.51572 10.895 11.6133 Q8TCW9 PKR1_HUMAN Prokineticin receptor 1 (PK-R1) (G-protein coupled receptor 73) (G-protein coupled receptor ZAQ) (GPR73a) PROKR1 GPR73 PKR1 Homo sapiens (Human) circadian rhythm [GO:0007623]; G protein-coupled receptor signaling pathway [GO:0007186] plasma membrane [GO:0005886] neuropeptide Y receptor activity [GO:0004983] 0.91452 -0.79606 KIMLLHWK 0 0 0 0 0 0 8.94711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TCX1 DC2L1_HUMAN Cytoplasmic dynein 2 light intermediate chain 1 (Dynein 2 light intermediate chain) DYNC2LI1 D2LIC LIC3 CGI-60 Homo sapiens (Human) determination of left/right symmetry [GO:0007368]; intraciliary retrograde transport [GO:0035721]; intraciliary transport involved in cilium assembly [GO:0035735]; regulation of cilium assembly [GO:1902017] apical part of cell [GO:0045177]; axoneme [GO:0005930]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary tip [GO:0097542]; ciliary transition zone [GO:0035869]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; microtubule [GO:0005874]; motile cilium [GO:0031514] dynein heavy chain binding [GO:0045504] 0.92068 -1.1432 DLELEQYKRSSSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.247 Q8TCX5 RHPN1_HUMAN Rhophilin-1 (GTP-Rho-binding protein 1) RHPN1 KIAA1929 Homo sapiens (Human) negative regulation of stress fiber assembly [GO:0051497]; proteolysis [GO:0006508]; signal transduction [GO:0007165] cytosol [GO:0005829] 0.96569 -2.7227 GLLRSQR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.75171 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TCY9 URGCP_HUMAN Up-regulator of cell proliferation (HBV X protein up-regulated gene 4 protein) (HBxAg up-regulated gene 4 protein) URGCP KIAA1507 URG4 Homo sapiens (Human) cell cycle [GO:0007049] cytosol [GO:0005829]; nucleus [GO:0005634] GTP binding [GO:0005525] 0.87807 0.019421 ALAGLAFCDPEK 0 0 0 0 0 0 0 0 0 0 0 0 9.56891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TD06 AGR3_HUMAN "Anterior gradient protein 3 (AG-3) (AG3) (hAG-3) (Anterior gradient 3 homolog) (Breast cancer membrane protein 11) (Protein disulfide isomerase family A, member 18)" AGR3 BCMP11 PDIA18 UNQ642/PRO1272 Homo sapiens (Human) negative regulation of cell death [GO:0060548] endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231] dystroglycan binding [GO:0002162] 0.8706 0.05916 ADIAGRYSNR 0 0 0 0 0 0 0 0 0 0 9.5901 8.78771 7.96058 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TD10 MIPO1_HUMAN Mirror-image polydactyly gene 1 protein MIPOL1 Homo sapiens (Human) nucleus [GO:0005634] identical protein binding [GO:0042802] 0.076172 1.2555 ENWSKDITHSYLEQETTGINK 0 0 0 0 0 0 0 0 0 0 0 10.7067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.7734 Q8TD16 BICD2_HUMAN Protein bicaudal D homolog 2 (Bic-D 2) BICD2 KIAA0699 Homo sapiens (Human) "centrosome localization [GO:0051642]; microtubule anchoring at microtubule organizing center [GO:0072393]; microtubule-based movement [GO:0007018]; minus-end-directed organelle transport along microtubule [GO:0072385]; mRNA transport [GO:0051028]; protein localization to Golgi apparatus [GO:0034067]; protein transport [GO:0015031]; regulation of microtubule cytoskeleton organization [GO:0070507]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]" annulate lamellae [GO:0005642]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; plasma membrane [GO:0005886] cytoskeletal anchor activity [GO:0008093]; dynactin binding [GO:0034452]; dynein complex binding [GO:0070840]; dynein light intermediate chain binding [GO:0051959]; small GTPase binding [GO:0031267] 0.26434 0.84843 EISERQLEEALETLK 13.0507 0 0 0 0 10.6986 0 0 0 12.2478 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TD19 NEK9_HUMAN Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9) (NimA-related kinase 8) (Nek8) NEK9 KIAA1995 NEK8 NERCC Homo sapiens (Human) cell division [GO:0051301]; mitotic cell cycle [GO:0000278]; protein phosphorylation [GO:0006468]; regulation of mitotic cell cycle [GO:0007346] cytosol [GO:0005829]; nucleus [GO:0005634] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase activator activity [GO:0030295]; protein kinase binding [GO:0019901]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.9602 -1.9838 LSEKERR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.149 0 0 0 0 Q8TD22 SFXN5_HUMAN Sideroflexin-5 SFXN5 Homo sapiens (Human) amino acid transport [GO:0006865]; citrate transport [GO:0015746]; mitochondrial transmembrane transport [GO:1990542]; positive regulation of cold-induced thermogenesis [GO:0120162] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] citrate transmembrane transporter activity [GO:0015137]; monoatomic ion transmembrane transporter activity [GO:0015075] 0.87131 0.034655 HGTLRPGVTNEQLWSAQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.68433 0 0 0 Q8TD23 ZN675_HUMAN Zinc finger protein 675 (TRAF6-binding zinc finger protein) (TRAF6-inhibitory zinc finger protein) ZNF675 TIZ Homo sapiens (Human) bone resorption [GO:0045453]; cytokine-mediated signaling pathway [GO:0019221]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of JNK cascade [GO:0046329]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] "DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]" 0.95954 -1.815 CEECGKAFSRSSK 15.3858 0 0 0 12.0005 0 0 14.8126 0 10.5541 0 10.341 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TD26 CHD6_HUMAN Chromodomain-helicase-DNA-binding protein 6 (CHD-6) (EC 3.6.4.12) (ATP-dependent helicase CHD6) (Radiation-induced gene B protein) CHD6 CHD5 KIAA1335 RIGB Homo sapiens (Human) cell redox homeostasis [GO:0045454]; chromatin remodeling [GO:0006338]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent activity, acting on DNA [GO:0008094]; ATP-dependent chromatin remodeler activity [GO:0140658]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; helicase activity [GO:0004386]; histone binding [GO:0042393]; transcription coregulator binding [GO:0001221]" 0.88168 0.0099334 HMERWMHGLENDEFEIEKPK 0 13.3443 12.9782 11.7806 0 0 12.6873 13.1865 13.2141 11.9449 0 0 11.57 0 10.0109 0 0 11.2429 0 9.44429 0 0 0 0 0 0 0 Q8TD43 TRPM4_HUMAN Transient receptor potential cation channel subfamily M member 4 (hTRPM4) (Calcium-activated non-selective cation channel 1) (Long transient receptor potential channel 4) (LTrpC-4) (LTrpC4) (Melastatin-4) TRPM4 LTRPC4 Homo sapiens (Human) adaptive immune response [GO:0002250]; calcium ion transmembrane transport [GO:0070588]; calcium-mediated signaling [GO:0019722]; cellular response to ATP [GO:0071318]; dendritic cell chemotaxis [GO:0002407]; inorganic cation transmembrane transport [GO:0098662]; membrane depolarization during AV node cell action potential [GO:0086045]; membrane depolarization during bundle of His cell action potential [GO:0086048]; membrane depolarization during Purkinje myocyte cell action potential [GO:0086047]; negative regulation of bone mineralization [GO:0030502]; negative regulation of osteoblast differentiation [GO:0045668]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of atrial cardiac muscle cell action potential [GO:1903949]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of heart rate [GO:0010460]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of regulation of vascular associated smooth muscle cell membrane depolarization [GO:1904199]; positive regulation of vasoconstriction [GO:0045907]; protein homotetramerization [GO:0051289]; protein sumoylation [GO:0016925]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of T cell cytokine production [GO:0002724]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; sodium ion import across plasma membrane [GO:0098719] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; sodium channel complex [GO:0034706] ATP binding [GO:0005524]; calcium activated cation channel activity [GO:0005227]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; ligand-gated calcium channel activity [GO:0099604]; sodium channel activity [GO:0005272] 0.96724 -3.7892 AQRYRLIR 9.76678 0 0 0 0 11.0865 0 0 0 0 11.9075 14.3604 0 9.54164 0 0 0 0 0 0 0 0 9.43902 0 0 0 10.2176 Q8TD46 MO2R1_HUMAN Cell surface glycoprotein CD200 receptor 1 (CD200 cell surface glycoprotein receptor) (Cell surface glycoprotein OX2 receptor 1) CD200R1 CD200R CRTR2 MOX2R OX2R UNQ2522/PRO6015 Homo sapiens (Human) heterotypic cell-cell adhesion [GO:0034113]; intracellular signal transduction [GO:0035556]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of macrophage migration [GO:1905522]; negative regulation of neuroinflammatory response [GO:0150079]; negative regulation of neuron death [GO:1901215]; negative regulation of T cell migration [GO:2000405]; regulation of neuroinflammatory response [GO:0150077]; signal transduction [GO:0007165] cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] glycosylated region protein binding [GO:0140081]; immunoglobulin receptor activity [GO:0019763]; signaling receptor activity [GO:0038023] 0.84467 0.15301 ETNCTDER 0 0 0 0 0 0 0 9.27242 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TD47 RS4Y2_HUMAN "Small ribosomal subunit protein eS4, Y isoform 2 (40S ribosomal protein S4, Y isoform 2)" RPS4Y2 RPS4Y2P Homo sapiens (Human) translation [GO:0006412] cytosolic small ribosomal subunit [GO:0022627] RNA binding [GO:0003723]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735] 0.51297 0.60297 KICMQHFLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.78095 0 0 0 0 0 0 Q8TD55 PKHO2_HUMAN Pleckstrin homology domain-containing family O member 2 (PH domain-containing family O member 2) (Pleckstrin homology domain-containing family Q member 1) (PH domain-containing family Q member 1) PLEKHO2 PLEKHQ1 PP9099 Homo sapiens (Human) macrophage apoptotic process [GO:0071888] extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813] 0.95114 -1.421 AQLEVKVASEQTEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6896 0 0 0 0 0 0 0 0 0 0 0 Q8TD57 DYH3_HUMAN Dynein axonemal heavy chain 3 (Axonemal beta dynein heavy chain 3) (HsADHC3) (Ciliary dynein heavy chain 3) (Dnahc3-b) DNAH3 DNAHC3B Homo sapiens (Human) cilium-dependent cell motility [GO:0060285]; microtubule-based movement [GO:0007018] axonemal dynein complex [GO:0005858]; dynein complex [GO:0030286]; microtubule [GO:0005874] ATP binding [GO:0005524]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; microtubule motor activity [GO:0003777]; minus-end-directed microtubule motor activity [GO:0008569] 0.96901 -3.9368 AMEVYDRVAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.55698 0 0 0 0 9.45921 9.36578 0 11.7759 0 0 Q8TD84 DSCL1_HUMAN Cell adhesion molecule DSCAML1 (Down syndrome cell adhesion molecule 2) (Down syndrome cell adhesion molecule-like protein 1) DSCAML1 DSCAM2 KIAA1132 Homo sapiens (Human) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; brain development [GO:0007420]; cell fate determination [GO:0001709]; central nervous system development [GO:0007417]; dendrite self-avoidance [GO:0070593]; dorsal/ventral pattern formation [GO:0009953]; embryonic skeletal system morphogenesis [GO:0048704]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] axon [GO:0030424]; cell surface [GO:0009986]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; synapse [GO:0045202] cell-cell adhesion mediator activity [GO:0098632]; protein homodimerization activity [GO:0042803] 0.96915 -3.0306 AGGPHTK 0 0 0 0 0 0 0 0 0 0 8.71822 0 0 0 0 0 0 0 9.57947 0 0 0 9.69556 0 0 0 0 Q8TD91 MAGC3_HUMAN Melanoma-associated antigen C3 (Cancer/testis antigen 7.2) (CT7.2) (Hepatocellular carcinoma-associated antigen 2) (MAGE-C3 antigen) MAGEC3 HCA2 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] 0.96397 -2.6497 AVSVKQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8518 0 0 0 0 0 0 0 0 Q8TDB6 DTX3L_HUMAN E3 ubiquitin-protein ligase DTX3L (EC 2.3.2.27) (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (RING-type E3 ubiquitin transferase DTX3L) (Rhysin-2) (Rhysin2) DTX3L BBAP Homo sapiens (Human) defense response to virus [GO:0051607]; DNA damage checkpoint signaling [GO:0000077]; DNA repair-dependent chromatin remodeling [GO:0140861]; double-strand break repair [GO:0006302]; endosome to lysosome transport [GO:0008333]; innate immune response [GO:0045087]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; Notch signaling pathway [GO:0007219]; positive regulation of chromatin binding [GO:0035563]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of receptor catabolic process [GO:2000646]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein transport [GO:0015031]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; histone binding [GO:0042393]; histone H4K91 ubiquitin ligase activity [GO:0141000]; histone ubiquitin ligase activity [GO:0140852]; metal ion binding [GO:0046872]; protein ADP-ribosyltransferase-substrate adaptor activity [GO:0140768]; STAT family protein binding [GO:0097677]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-protein transferase activity [GO:0004842] 0.92149 -1.1273 AFDQKLIFTVGYSR 10.098 9.89271 10.0157 8.94298 0 0 9.7687 9.93278 9.8464 0 0 0 0 0 0 9.93933 0 0 0 0 0 0 0 0 0 0 0 Q8TDD1 DDX54_HUMAN ATP-dependent RNA helicase DDX54 (EC 3.6.4.13) (ATP-dependent RNA helicase DP97) (DEAD box RNA helicase 97 kDa) (DEAD box protein 54) DDX54 Homo sapiens (Human) intracellular estrogen receptor signaling pathway [GO:0030520]; RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]; rRNA processing [GO:0006364] Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; nuclear estrogen receptor binding [GO:0030331]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714] 0.8841 -0.15602 DLCSQVMRAKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.66933 0 0 9.75482 0 0 0 Q8TDD2 SP7_HUMAN Transcription factor Sp7 (Zinc finger protein osterix) SP7 OSX Homo sapiens (Human) cellular response to zinc ion starvation [GO:0034224]; cementum mineralization [GO:0071529]; diphosphate metabolic process [GO:0071344]; hematopoietic stem cell differentiation [GO:0060218]; osteoblast differentiation [GO:0001649]; positive regulation of stem cell differentiation [GO:2000738]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of hydrolase activity [GO:0051336]; regulation of transcription by RNA polymerase II [GO:0006357]; response to insulin [GO:0032868]; response to organic cyclic compound [GO:0014070] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleus [GO:0005634] "DEAD/H-box RNA helicase binding [GO:0017151]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.87037 0.054356 KPIHSCHIPGCGK 0 0 0 10.8338 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TDD5 MCLN3_HUMAN Mucolipin-3 (Transient receptor potential channel mucolipin 3) (TRPML3) MCOLN3 Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; inner ear auditory receptor cell differentiation [GO:0042491]; locomotory behavior [GO:0007626] autophagosome membrane [GO:0000421]; early endosome membrane [GO:0031901]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886] calcium channel activity [GO:0005262]; lipid binding [GO:0008289]; NAADP-sensitive calcium-release channel activity [GO:0072345] 0.92739 -1.1885 KLKFFFMNPCEK 0 0 10.409 0 0 0 0 0 0 0 11.699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TDF6 GRP4_HUMAN RAS guanyl-releasing protein 4 RASGRP4 Homo sapiens (Human) activation of phospholipase C activity [GO:0007202]; cell population proliferation [GO:0008283]; myeloid cell differentiation [GO:0030099]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Ras protein signal transduction [GO:0046579]; Ras protein signal transduction [GO:0007265]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to extracellular stimulus [GO:0009991]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; diacylglycerol binding [GO:0019992]; GTP-dependent protein binding [GO:0030742]; guanyl-nucleotide exchange factor activity [GO:0005085] 0.9694 -3.1425 EGNSAQRR 0 0 0 0 0 9.61338 0 0 0 9.47587 9.09735 0 0 9.111 0 0 0 9.92767 0 0 10.2535 0 0 0 0 0 0 Q8TDG2 ACTT1_HUMAN Actin-related protein T1 (ARP-T1) ACTRT1 ARPT1 HSD27 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; regulation of DNA-templated transcription [GO:0006355]; regulation of smoothened signaling pathway [GO:0008589] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; nucleus [GO:0005634] chromatin binding [GO:0003682] 0.92264 -1.0846 DITEHLTR 0 0 0 0 0 0 0 11.23 0 0 0 0 0 0 0 0 0 9.43133 0 0 0 0 0 0 0 0 0 Q8TDG4 HELQ_HUMAN Helicase POLQ-like (EC 3.6.4.12) (Mus308-like helicase) (POLQ-like helicase) HELQ HEL308 Homo sapiens (Human) DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via synthesis-dependent strand annealing [GO:0045003]; positive regulation of double-strand break repair via homologous recombination [GO:1905168] nucleus [GO:0005634]; site of DNA damage [GO:0090734] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA binding [GO:0003677]; single-stranded 3'-5' DNA helicase activity [GO:1990518] 0.96482 -2.7033 AENGMTFSRLLNYK 0 0 0 11.6954 0 0 0 11.5143 0 0 0 0 0 0 0 8.92333 0 0 0 0 0 0 0 0 0 10.5794 10.3007 Q8TDI0 CHD5_HUMAN Chromodomain-helicase-DNA-binding protein 5 (CHD-5) (EC 3.6.4.12) (ATP-dependent helicase CHD5) CHD5 KIAA0444 Homo sapiens (Human) cerebral cortex neuron differentiation [GO:0021895]; chromatin remodeling [GO:0006338]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of signal transduction by p53 class mediator [GO:1901798]; regulation of transcription by RNA polymerase II [GO:0006357]; sperm DNA condensation [GO:0035092] chromatin [GO:0000785]; cytosol [GO:0005829]; heterochromatin [GO:0000792]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NuRD complex [GO:0016581] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent chromatin remodeler activity [GO:0140658]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; H3K27me3 modified histone binding [GO:0061628]; helicase activity [GO:0004386]; histone binding [GO:0042393]; metal ion binding [GO:0046872] 0.91422 -0.80246 DEDEDDNDDGCLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1298 0 0 Q8TDI7 TMC2_HUMAN Transmembrane channel-like protein 2 (Transmembrane cochlear-expressed protein 2) TMC2 C20orf145 UNQ907/PRO1928 Homo sapiens (Human) detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; regulation of calcium ion transmembrane transport [GO:1903169]; vestibular reflex [GO:0060005] plasma membrane [GO:0005886]; stereocilium tip [GO:0032426] mechanosensitive monoatomic ion channel activity [GO:0008381]; voltage-gated calcium channel activity [GO:0005245] 0.96918 -3.5943 AGGSPSPGSPR 0 8.82248 9.0659 0 0 0 9.97757 9.89529 9.90043 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TDI8 TMC1_HUMAN Transmembrane channel-like protein 1 (Transmembrane cochlear-expressed protein 1) TMC1 Homo sapiens (Human) auditory receptor cell development [GO:0060117]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; regulation of calcium ion transmembrane transport [GO:1903169]; vestibular reflex [GO:0060005] external side of plasma membrane [GO:0009897]; stereocilium tip [GO:0032426] mechanosensitive monoatomic ion channel activity [GO:0008381]; voltage-gated calcium channel activity [GO:0005245] 0.67376 0.39371 AAAAAGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.39069 0 0 0 0 0 0 0 0 0 0 0 0 Q8TDJ6 DMXL2_HUMAN DmX-like protein 2 (Rabconnectin-3) DMXL2 KIAA0856 Homo sapiens (Human) vacuolar acidification [GO:0007035] extracellular space [GO:0005615]; neuronal dense core vesicle [GO:0098992]; RAVE complex [GO:0043291]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672] small GTPase binding [GO:0031267] 0.92343 -1.0468 AMLEPENTPFKSR 0 0 0 0 0 0 0 0 0 0 0 8.40998 10.2354 0 10.7732 8.39129 0 0 0 0 0 0 0 8.94991 0 11.9629 0 Q8TDL5 BPIB1_HUMAN "BPI fold-containing family B member 1 (Long palate, lung and nasal epithelium carcinoma-associated protein 1) (von Ebner minor salivary gland protein) (VEMSGP)" BPIFB1 C20orf114 LPLUNC1 UNQ706/PRO1357 Homo sapiens (Human) innate immune response in mucosa [GO:0002227]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144] extracellular exosome [GO:0070062]; extracellular region [GO:0005576] lipid binding [GO:0008289] 0.84731 0.12711 TIVEFHMTTEAQATIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.90289 0 0 0 0 0 0 Q8TDM6 DLG5_HUMAN Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG) DLG5 KIAA0583 PDLG Homo sapiens (Human) apical protein localization [GO:0045176]; cell-cell adhesion [GO:0098609]; epithelial to mesenchymal transition [GO:0001837]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular signal transduction [GO:0035556]; maintenance of cell polarity [GO:0030011]; metanephric collecting duct development [GO:0072205]; midbrain development [GO:0030901]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of hippo signaling [GO:0035331]; negative regulation of T cell proliferation [GO:0042130]; neuroepithelial cell differentiation [GO:0060563]; polarized epithelial cell differentiation [GO:0030859]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of hippo signaling [GO:0035332]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of synapse assembly [GO:0051965]; postsynapse organization [GO:0099173]; protein localization to adherens junction [GO:0071896]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165]; zonula adherens assembly [GO:0045186] adherens junction [GO:0005912]; cell junction [GO:0030054]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] beta-catenin binding [GO:0008013]; cytoskeletal protein binding [GO:0008092]; signaling receptor complex adaptor activity [GO:0030159] 0.97011 -3.2821 DAVYSEYK 10.5914 11.3912 13.5751 9.21447 8.29971 0 8.98025 13.1118 0 10.2466 10.7058 12.7202 9.99492 0 10.6549 11.867 0 9.71354 0 0 0 10.6344 8.35993 0 0 0 0 Q8TDN2 KCNV2_HUMAN Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2) KCNV2 Homo sapiens (Human) potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of monoatomic ion transmembrane transport [GO:0034765] plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076] voltage-gated potassium channel activity [GO:0005249] 0.96279 -2.0918 LASTPDLRR 0 0 0 9.60021 0 0 11.1901 0 9.81625 0 0 0 0 11.5278 0 10.2403 0 0 0 0 0 10.194 0 0 10.5756 0 0 Q8TDN6 BRX1_HUMAN Ribosome biogenesis protein BRX1 homolog (Brix domain-containing protein 2) BRIX1 BRIX BXDC2 Homo sapiens (Human) ribosomal large subunit assembly [GO:0000027]; rRNA processing [GO:0006364] chromosome [GO:0005694]; nucleolus [GO:0005730] RNA binding [GO:0003723]; rRNA binding [GO:0019843] 0.92267 -1.0828 DRIPGPVCK 0 0 0 0 0 0 0 9.07513 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TDQ1 CLM1_HUMAN CMRF35-like molecule 1 (CLM-1) (CD300 antigen-like family member F) (Immune receptor expressed on myeloid cells 1) (IREM-1) (Immunoglobulin superfamily member 13) (IgSF13) (NK inhibitory receptor) (CD antigen CD300f) CD300LF CD300F CLM1 IGSF13 IREM1 NKIR UNQ3105/PRO10111 Homo sapiens (Human) interleukin-13-mediated signaling pathway [GO:0035772]; negative regulation of apoptotic cell clearance [GO:2000426]; negative regulation of mast cell activation [GO:0033004]; negative regulation of MyD88-dependent toll-like receptor signaling pathway [GO:0034125]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of interleukin-4-mediated signaling pathway [GO:1902216]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666] plasma membrane [GO:0005886] ceramide binding [GO:0097001]; identical protein binding [GO:0042802]; interleukin-4 receptor binding [GO:0005136]; phosphatidylserine binding [GO:0001786]; transmembrane signaling receptor activity [GO:0004888] 0.9336 -1.2816 GAIWRDCK 0 0 0 0 0 0 0 9.91316 0 0 9.69572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TDR0 MIPT3_HUMAN TRAF3-interacting protein 1 (Interleukin-13 receptor alpha 1-binding protein 1) (Intraflagellar transport protein 54 homolog) (Microtubule-interacting protein associated with TRAF3) (MIP-T3) TRAF3IP1 IFT54 MIPT3 Homo sapiens (Human) cilium assembly [GO:0060271]; intraciliary anterograde transport [GO:0035720]; intraciliary transport [GO:0042073]; kidney development [GO:0001822]; morphogenesis of a polarized epithelium [GO:0001738]; negative regulation of defense response to virus [GO:0050687]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of type I interferon production [GO:0032480]; regulation of microtubule cytoskeleton organization [GO:0070507] axoneme [GO:0005930]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary base [GO:0097546]; ciliary tip [GO:0097542]; ciliary transition zone [GO:0035869]; cilium [GO:0005929]; intraciliary transport particle B [GO:0030992] microtubule binding [GO:0008017] 0.95537 -1.5855 EDRKPREK 0 0 0 0 0 0 12.3061 0 0 0 0 0 0 0 0 0 0 0 0 12.6121 0 0 10.9618 0 0 10.2796 0 Q8TDR2 STK35_HUMAN Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting kinase 1) (Serine/threonine-protein kinase 35 L1) STK35 CLIK1 PDIK1 STK35L1 Homo sapiens (Human) autophagy [GO:0006914]; protein phosphorylation [GO:0006468] cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.23695 0.85065 LVETSLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1642 0 0 0 0 0 0 0 0 0 0 0 Q8TDR4 TCP1L_HUMAN T-complex protein 10A homolog 1 (T-complex protein 10A-1) (TCP10A-1) (TCP10-like) TCP10L PRED77 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] DNA-binding transcription factor binding [GO:0140297]; identical protein binding [GO:0042802]; protein self-association [GO:0043621]; transcription corepressor activity [GO:0003714] 0.92188 -1.1039 EKLRALQLQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.10565 0 0 0 0 0 0 0 Q8TDS5 OXER1_HUMAN Oxoeicosanoid receptor 1 (5-oxo-ETE G-protein coupled receptor) (G-protein coupled receptor 170) (G-protein coupled receptor R527) (G-protein coupled receptor TG1019) OXER1 GPR170 TG1019 Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; G protein-coupled receptor signaling pathway [GO:0007186] plasma membrane [GO:0005886] "5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding [GO:0050648]; 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding [GO:0050647]; 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding [GO:0050646]; G protein-coupled receptor activity [GO:0004930]" 0.41491 0.6845 FGAAACK 0 0 0 0 0 0 0 0 0 0 10.3779 0 0 0 0 0 11.0604 0 0 0 0 0 0 0 0 0 0 Q8TDU9 RL3R2_HUMAN Relaxin-3 receptor 2 (RLN3 receptor 2) (G-protein coupled receptor 100) (G-protein coupled receptor GPCR142) (Insulin-like peptide INSL5 receptor) (Relaxin family peptide receptor 4) RXFP4 GPCR142 GPR100 RLN3R2 Homo sapiens (Human) neuropeptide signaling pathway [GO:0007218]; positive regulation of feeding behavior [GO:2000253] plasma membrane [GO:0005886] G protein-coupled peptide receptor activity [GO:0008528] 0.16908 0.97271 ESRPSTLLTNLDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.47474 0 0 0 0 0 0 0 9.43311 Q8TDV0 GP151_HUMAN G-protein coupled receptor 151 (G-protein coupled receptor PGR7) (GPCR-2037) (Galanin receptor 4) (Galanin-receptor-like protein) (GalRL) GPR151 GALR4 GALRL PGR7 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of immune response [GO:0050778]; response to acidic pH [GO:0010447]; response to ischemia [GO:0002931] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; identical protein binding [GO:0042802]; neuropeptide receptor activity [GO:0008188] 0.94096 -1.3129 AYDQCKKR 0 0 0 10.8464 0 0 0 0 8.46626 0 0 0 9.53568 9.50351 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TDW4 ST7L_HUMAN Suppressor of tumorigenicity 7 protein-like (ST7-related protein) ST7L ST7R Homo sapiens (Human) negative regulation of cell growth [GO:0030308] membrane [GO:0016020] 0.96759 -2.7401 GDSEAIAYAFFHLQHWKR 0 0 0 0 9.99746 0 0 0 0 10.1223 0 0 0 0 9.4937 0 0 0 0 0 0 0 0 0 0 0 0 Q8TDW7 FAT3_HUMAN Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3) FAT3 CDHF15 KIAA1989 Homo sapiens (Human) cell morphogenesis involved in differentiation [GO:0000904]; dendrite development [GO:0016358]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; interneuron migration [GO:1904936]; negative regulation of dendrite development [GO:2000171]; retina layer formation [GO:0010842] dendrite [GO:0030425]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.96847 -8.6965 ATDGGGR 0 0 0 0 0 0 0 0 0 0 10.6934 0 0 0 0 0 0 0 11.4854 0 0 0 0 0 0 9.5889 0 Q8TDX6 CGAT1_HUMAN "Chondroitin sulfate N-acetylgalactosaminyltransferase 1 (CsGalNAcT-1) (EC 2.4.1.174) (Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1) (Beta4GalNAcT-1)" CSGALNACT1 CHGN GALNACT1 UNQ656/PRO1287 Homo sapiens (Human) "cartilage development [GO:0051216]; chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate proteoglycan biosynthetic process [GO:0050650]; chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0050653]; dermatan sulfate proteoglycan biosynthetic process [GO:0050651]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; heparin biosynthetic process [GO:0030210]; proteoglycan biosynthetic process [GO:0030166]; UDP-glucuronate metabolic process [GO:0046398]; UDP-N-acetylgalactosamine metabolic process [GO:0019276]" Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139] acetylgalactosaminyltransferase activity [GO:0008376]; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity [GO:0047238]; glucuronosyltransferase activity [GO:0015020]; glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity [GO:0047237]; metal ion binding [GO:0046872]; peptidoglycan glycosyltransferase activity [GO:0008955] 0.8997 -0.68463 GTLYELTFK 0 0 9.44911 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TDX7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 (EC 2.7.11.34) (Never in mitosis A-related kinase 7) (NimA-related protein kinase 7) NEK7 Homo sapiens (Human) cellular response to potassium ion [GO:0035865]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein phosphorylation [GO:0006468]; regulation of mitotic cell cycle [GO:0007346]; spindle assembly [GO:0051225] cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule organizing center [GO:0005815]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular function activator activity [GO:0140677]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.8818 -0.02481 ADCIKEIDLLK 14.0551 13.8785 0 8.87698 10.4609 9.98071 12.7653 0 0 10.2982 0 12.3192 0 0 11.943 11.008 0 0 0 0 0 0 0 0 0 11.0651 0 Q8TDX9 PK1L1_HUMAN Polycystin-1-like protein 1 (Polycystin-1L1) (PC1-like 1 protein) (Polycystic kidney disease protein 1-like 1) PKD1L1 UNQ5785/PRO19563 Homo sapiens (Human) cell-cell adhesion [GO:0098609]; detection of mechanical stimulus [GO:0050982]; detection of nodal flow [GO:0003127]; left/right axis specification [GO:0070986] calcium channel complex [GO:0034704]; ciliary membrane [GO:0060170]; cilium [GO:0005929]; membrane [GO:0016020]; non-motile cilium [GO:0097730] calcium channel activity [GO:0005262] 0.96444 -2.3995 HLRWAHPPSKAQLR 0 0 0 0 0 0 0 0 0 0 0 0 0 11.223 0 0 0 0 0 0 10.0592 0 0 0 0 0 0 Q8TDY2 RBCC1_HUMAN RB1-inducible coiled-coil protein 1 (FAK family kinase-interacting protein of 200 kDa) (FIP200) RB1CC1 KIAA0203 RBICC Homo sapiens (Human) autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; autophagy of peroxisome [GO:0030242]; cell cycle [GO:0007049]; extrinsic apoptotic signaling pathway [GO:0097191]; glycophagy [GO:0061723]; heart development [GO:0007507]; liver development [GO:0001889]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; piecemeal microautophagy of the nucleus [GO:0034727]; positive regulation of autophagy [GO:0010508]; positive regulation of cell size [GO:0045793]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein phosphorylation [GO:0001934]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of protein lipidation [GO:1903059]; reticulophagy [GO:0061709] Atg1/ULK1 kinase complex [GO:1990316]; autophagosome membrane [GO:0000421]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; lysosome [GO:0005764]; nuclear membrane [GO:0031965]; phagophore assembly site [GO:0000407]; phagophore assembly site membrane [GO:0034045] molecular adaptor activity [GO:0060090]; protein kinase binding [GO:0019901] 0.96994 -4.1474 AIKGLEDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2856 0 0 0 8.76742 0 0 11.4217 0 0 0 Q8TDY3 ACTT2_HUMAN Actin-related protein T2 (ARP-T2) (Actin-related protein M2) ACTRT2 ARPM2 Homo sapiens (Human) cytoplasm [GO:0005737]; cytoskeleton [GO:0005856] 0.88335 -0.085844 EFGTSVVQRRCF 0 0 0 0 0 0 0 0 0 0 0 0 9.98285 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TDY4 ASAP3_HUMAN "Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 (Development and differentiation-enhancing factor-like 1) (Protein up-regulated in liver cancer 1)" ASAP3 DDEFL1 UPLC1 Homo sapiens (Human) cell migration [GO:0016477]; positive regulation of GTPase activity [GO:0043547]; regulation of stress fiber assembly [GO:0051492] cytosol [GO:0005829]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; ruffle [GO:0001726] GTPase activator activity [GO:0005096]; metal ion binding [GO:0046872] 0.88225 -0.11531 LWTAICNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.85184 0 0 0 0 0 Q8TDY8 IGDC4_HUMAN Immunoglobulin superfamily DCC subclass member 4 (Neighbor of punc e11) (Protein DDM36) (hDDM36) IGDCC4 DDM36 KIAA1628 NOPE Homo sapiens (Human) cell-cell adhesion [GO:0098609] plasma membrane [GO:0005886] 0.9692 -3.3761 IVNYTVR 11.3125 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TE12 LMX1A_HUMAN LIM homeobox transcription factor 1-alpha (LIM/homeobox protein 1.1) (LMX-1.1) (LIM/homeobox protein LMX1A) LMX1A Homo sapiens (Human) axon guidance [GO:0007411]; central nervous system neuron differentiation [GO:0021953]; cerebellum development [GO:0021549]; dentate gyrus development [GO:0021542]; dopaminergic neuron differentiation [GO:0071542]; locomotory behavior [GO:0007626]; memory [GO:0007613]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of neuron differentiation [GO:0045665]; neuron differentiation [GO:0030182]; olfactory behavior [GO:0042048]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell growth [GO:0001558]; regulation of transcription by RNA polymerase II [GO:0006357]; synapse organization [GO:0050808] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96923 -3.2074 EGQLLCKGDYEK 0 0 0 0 0 0 0 0 0 10.3194 0 0 0 0 0 8.65807 0 0 0 0 0 0 0 0 0 0 9.6905 Q8TE49 OTU7A_HUMAN OTU domain-containing protein 7A (EC 3.4.19.12) (Zinc finger protein Cezanne 2) OTUD7A C15orf16 CEZANNE2 OTUD7 Homo sapiens (Human) protein deubiquitination [GO:0016579]; protein deubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0071947]; protein K11-linked deubiquitination [GO:0035871]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] cysteine-type deubiquitinase activity [GO:0004843]; DNA binding [GO:0003677]; K63-linked polyubiquitin modification-dependent protein binding [GO:0070530]; zinc ion binding [GO:0008270] 0.76411 0.28737 TVNTVESLAR 0 0 0 0 0 0 0 0 9.67311 11.2013 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TE56 ATS17_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 17 (ADAM-TS 17) (ADAM-TS17) (ADAMTS-17) (EC 3.4.24.-) ADAMTS17 Homo sapiens (Human) extracellular matrix organization [GO:0030198]; proteolysis [GO:0006508] extracellular matrix [GO:0031012]; extracellular region [GO:0005576] metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222] 0.90706 -0.74127 DLRFLSRGFEVEEAGAAR 0 0 0 0 0 0 0 0 0 9.87557 0 0 0 0 0 0 0 0 10.3082 0 0 0 10.2215 0 0 0 0 Q8TE58 ATS15_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 15 (ADAM-TS 15) (ADAM-TS15) (ADAMTS-15) (EC 3.4.24.-) ADAMTS15 Homo sapiens (Human) extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; myoblast fusion [GO:0007520]; proteolysis [GO:0006508] cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615] endopeptidase activity [GO:0004175]; extracellular matrix binding [GO:0050840]; heparin binding [GO:0008201]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270] 0.96961 -6.017 EDKSSHPK 0 0 0 0 0 8.8715 0 0 0 10.3376 9.5299 0 0 10.2312 0 0 9.09207 0 0 0 0 0 0 0 0 0 0 Q8TE59 ATS19_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 19 (ADAM-TS 19) (ADAM-TS19) (ADAMTS-19) (EC 3.4.24.-) ADAMTS19 Homo sapiens (Human) extracellular matrix organization [GO:0030198]; proteolysis [GO:0006508] extracellular matrix [GO:0031012]; extracellular region [GO:0005576] metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222] 0.9536 -1.4995 DCNGPRKQYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.99958 9.8438 0 8.32962 10.1055 0 10.7791 9.48613 8.80903 8.36663 0 10.3226 Q8TE60 ATS18_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 18 (ADAM-TS 18) (ADAM-TS18) (ADAMTS-18) (EC 3.4.24.-) ADAMTS18 ADAMTS21 Homo sapiens (Human) extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; negative regulation of platelet aggregation [GO:0090331]; proteolysis [GO:0006508] extracellular matrix [GO:0031012]; extracellular region [GO:0005576] metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222] 0.97006 -5.1367 FDEYGSSGRPRRSAGK 0 0 0 0 0 0 13.8102 0 0 0 10.717 0 0 0 0 8.96815 0 0 0 0 0 0 0 0 0 0 9.83202 Q8TE67 ES8L3_HUMAN Epidermal growth factor receptor kinase substrate 8-like protein 3 (EPS8-like protein 3) (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-related protein 3) EPS8L3 EPS8R3 Homo sapiens (Human) positive regulation of ruffle assembly [GO:1900029]; regulation of hair cycle [GO:0042634]; regulation of Rho protein signal transduction [GO:0035023]; Rho protein signal transduction [GO:0007266] cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587] actin binding [GO:0003779] 0.86293 0.080401 DGWLQLLDIETKEELDSYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7815 0 Q8TE73 DYH5_HUMAN Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) DNAH5 DNAHC5 HL1 KIAA1603 Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158] 9+0 motile cilium [GO:0097728]; 9+2 motile cilium [GO:0097729]; axoneme [GO:0005930]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; microtubule [GO:0005874]; motile cilium [GO:0031514]; outer dynein arm [GO:0036157] ATP binding [GO:0005524]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; minus-end-directed microtubule motor activity [GO:0008569] 0.95957 -1.8823 ARKIPFGK 0 0 10.6434 0 0 10.7171 0 0 0 10.2722 10.5618 0 0 10.239 0 9.05412 0 0 9.72596 9.3127 10.595 0 0 9.45156 0 11.4579 0 Q8TE76 MORC4_HUMAN MORC family CW-type zinc finger protein 4 (Zinc finger CW-type coiled-coil domain protein 2) (Zinc finger CW-type domain protein 4) MORC4 ZCW4 ZCWCC2 Homo sapiens (Human) nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP hydrolysis activity [GO:0016887]; methylated histone binding [GO:0035064]; zinc ion binding [GO:0008270] 0.96429 -2.4327 AELERTKEEK 0 10.0455 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.75452 0 0 0 0 Q8TE77 SSH3_HUMAN Protein phosphatase Slingshot homolog 3 (EC 3.1.3.16) (EC 3.1.3.48) (SSH-like protein 3) (SSH-3L) (hSSH-3L) SSH3 SSH3L Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; negative regulation of actin filament polymerization [GO:0030837]; protein dephosphorylation [GO:0006470] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; nucleus [GO:0005634] actin binding [GO:0003779]; myosin phosphatase activity [GO:0017018]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138] 0.80978 0.22614 VVGMEESQAAPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.32773 0 0 Q8TE82 S3TC1_HUMAN SH3 domain and tetratricopeptide repeat-containing protein 1 SH3TC1 Homo sapiens (Human) 0.96948 -3.442 AGPEEAK 0 9.05824 0 0 0 0 0 0 9.05775 0 0 0 0 0 0 0 0 0 0 8.60689 0 9.23458 0 0 0 0 0 Q8TE85 GRHL3_HUMAN Grainyhead-like protein 3 homolog (Sister of mammalian grainyhead) (Transcription factor CP2-like 4) GRHL3 SOM TFCP2L4 Homo sapiens (Human) central nervous system development [GO:0007417]; cochlea morphogenesis [GO:0090103]; ectoderm development [GO:0007398]; epidermis development [GO:0008544]; establishment of planar polarity [GO:0001736]; establishment of skin barrier [GO:0061436]; eyelid development in camera-type eye [GO:0061029]; neural tube closure [GO:0001843]; pattern specification process [GO:0007389]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366]; wound healing [GO:0042060] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "chromatin DNA binding [GO:0031490]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]" 0.88173 -0.026522 FWKHWHSRQPTAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.273 10.7223 0 0 9.41193 10.1808 0 0 0 0 0 0 Q8TE96 DQX1_HUMAN ATP-dependent RNA helicase DQX1 (EC 3.6.4.12) (DEAQ box polypeptide 1) DQX1 Homo sapiens (Human) spliceosomal complex [GO:0005681] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; helicase activity [GO:0004386]; RNA binding [GO:0003723] 0.92453 -0.98947 AVQAVYEDMDARK 0 0 0 0 0 0 9.52501 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TE99 PXYP1_HUMAN 2-phosphoxylose phosphatase 1 (EC 3.1.3.-) (Acid phosphatase-like protein 2) (Xylosyl phosphatase) (epididymis luminal protein 124) PXYLP1 ACPL2 HEL124 XYLP UNQ370/PRO706 Homo sapiens (Human) chondroitin sulfate proteoglycan biosynthetic process [GO:0050650]; dephosphorylation [GO:0016311]; glycosaminoglycan biosynthetic process [GO:0006024]; positive regulation of heparan sulfate proteoglycan biosynthetic process [GO:0010909] Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139] phosphatase activity [GO:0016791] 0.89772 -0.56377 HGDRYPLYVIPK 0 0 0 0 0 0 12.4015 12.4707 12.6061 0 12.6756 12.3756 0 0 9.18782 10.8415 11.3357 10.865 0 0 0 0 0 0 0 0 0 Q8TEA1 NSUN6_HUMAN tRNA (cytosine(72)-C(5))-methyltransferase NSUN6 (EC 2.1.1.-) (NOL1/NOP2/Sun and PUA domain-containing protein 1) (NOL1/NOP2/Sun domain family member 6) NSUN6 NOPD1 Homo sapiens (Human) RNA methylation [GO:0001510]; tRNA C5-cytosine methylation [GO:0002946]; tRNA methylation [GO:0030488]; tRNA modification [GO:0006400] cytoplasm [GO:0005737]; cytosol [GO:0005829] tRNA (cytosine-5-)-methyltransferase activity [GO:0016428]; tRNA binding [GO:0000049] 0.75633 0.30698 EIFSGLPELK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5143 0 0 0 0 0 0 0 0 0 0 Q8TEA7 TBCK_HUMAN TBC domain-containing protein kinase-like protein TBCK TBCKL HSPC302 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; activation of GTPase activity [GO:0090630]; cell population proliferation [GO:0008283]; regulation of TOR signaling [GO:0032006] cytoplasm [GO:0005737]; midbody [GO:0030496]; mitotic spindle [GO:0072686] ATP binding [GO:0005524]; GTPase activator activity [GO:0005096]; protein kinase activity [GO:0004672] 0.8648 0.084484 ELPETVIDLLNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.96028 0 0 Q8TEA8 DTD1_HUMAN D-aminoacyl-tRNA deacylase 1 (DTD) (EC 3.1.1.96) (DNA-unwinding element-binding protein B) (DUE-B) (Gly-tRNA(Ala) deacylase) (Histidyl-tRNA synthase-related) DTD1 C20orf88 DUEB HARS2 Homo sapiens (Human) DNA duplex unwinding [GO:0032508]; DNA replication [GO:0006260]; tRNA metabolic process [GO:0006399] cytoplasm [GO:0005737]; nucleus [GO:0005634] D-tyrosyl-tRNA(Tyr) deacylase activity [GO:0051500]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; tRNA binding [GO:0000049] 0.96721 -3.751 ELEHMVR 8.13566 0 0 0 0 0 0 0 8.84593 0 0 9.07315 0 0 0 0 0 0 0 0 0 0 0 0 0 9.36586 0 Q8TEB1 DCA11_HUMAN DDB1- and CUL4-associated factor 11 (WD repeat-containing protein 23) DCAF11 WDR23 GL014 PRO2389 Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567] Cul4-RING E3 ubiquitin ligase complex [GO:0080008]; nucleoplasm [GO:0005654] 0.95105 -1.4133 ELEFNEIK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2312 0 0 0 0 0 0 0 0 9.5504 0 0 0 0 Q8TEB7 RN128_HUMAN E3 ubiquitin-protein ligase RNF128 (EC 2.3.2.27) (Gene related to anergy in lymphocytes protein) (GRAIL) (RING finger protein 128) (RING-type E3 ubiquitin transferase RNF128) RNF128 Homo sapiens (Human) negative regulation of cytokine production [GO:0001818]; positive regulation of protein catabolic process in the vacuole [GO:1904352]; protein localization to lysosome [GO:0061462]; protein ubiquitination [GO:0016567]; regulation of protein stability [GO:0031647]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630] 0.89708 -0.67158 ILTCNHIFHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.59152 0 0 0 0 0 0 0 0 Q8TEB9 RHBL4_HUMAN Rhomboid-related protein 4 (RRP4) (EC 3.4.21.105) (Rhomboid domain-containing protein 1) (Rhomboid-like protein 4) RHBDD1 RHBDL4 HSD-50 HSD50 Homo sapiens (Human) "apoptotic process [GO:0006915]; cellular response to unfolded protein [GO:0034620]; cellular response to UV [GO:0034644]; ERAD pathway [GO:0036503]; membrane protein intracellular domain proteolysis [GO:0031293]; membrane protein proteolysis [GO:0033619]; membrane protein proteolysis involved in retrograde protein transport, ER to cytosol [GO:1904211]; negative regulation of apoptotic process [GO:0043066]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein processing [GO:0010954]; positive regulation of secretion [GO:0051047]; post-translational protein modification [GO:0043687]; spermatid differentiation [GO:0048515]" endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum quality control compartment [GO:0044322]; mitochondrial membrane [GO:0031966] endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252] 0.78655 0.24869 ALQASLWDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.53712 0 0 0 Q8TEC5 SH3R2_HUMAN E3 ubiquitin-protein ligase SH3RF2 (EC 2.3.2.27) (Heart protein phosphatase 1-binding protein) (HEPP1) (POSH-eliminating RING protein) (Protein phosphatase 1 regulatory subunit 39) (RING finger protein 158) (RING-type E3 ubiquitin transferase SH3RF2) (SH3 domain-containing RING finger protein 2) SH3RF2 POSH3 POSHER PPP1R39 RNF158 Homo sapiens (Human) negative regulation of apoptotic process [GO:0043066]; negative regulation of JNK cascade [GO:0046329]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of cell migration [GO:0030335]; positive regulation of JNK cascade [GO:0046330]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567] nucleoplasm [GO:0005654]; nucleus [GO:0005634] metal ion binding [GO:0046872]; phosphatase binding [GO:0019902]; protein phosphatase 1 binding [GO:0008157]; protein phosphatase inhibitor activity [GO:0004864]; ubiquitin protein ligase activity [GO:0061630] 0.96239 -2.5495 NLSLVSSSSR 0 0 0 0 0 0 0 0 0 9.28265 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TED0 UTP15_HUMAN U3 small nucleolar RNA-associated protein 15 homolog UTP15 Homo sapiens (Human) positive regulation of rRNA processing [GO:2000234]; positive regulation of transcription by RNA polymerase I [GO:0045943]; ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364] cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; fibrillar center [GO:0001650]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040] RNA binding [GO:0003723] 0.95429 -1.535 AVHTVDFTADK 0 10.8312 0 11.7415 0 0 0 0 0 0 0 0 0 0 0 9.50849 0 0 0 0 0 0 0 0 0 10.18 0 Q8TED1 GPX8_HUMAN Probable glutathione peroxidase 8 (GPx-8) (GSHPx-8) (EC 1.11.1.9) GPX8 UNQ847/PRO1785 Homo sapiens (Human) cellular response to oxidative stress [GO:0034599] endoplasmic reticulum lumen [GO:0005788]; membrane [GO:0016020] glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601] 0.95111 -1.4335 EPRWNFWK 0 0 9.77292 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.62651 0 0 Q8TED4 G6PT3_HUMAN Glucose-6-phosphate exchanger SLC37A2 (Solute carrier family 37 member 2) SLC37A2 Homo sapiens (Human) carbohydrate transport [GO:0008643]; glucose-6-phosphate transport [GO:0015760]; phosphate ion transmembrane transport [GO:0035435] endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062] glucose 6-phosphate:inorganic phosphate antiporter activity [GO:0061513] 0.88317 -0.060766 CSKGPCEEPAAISFFGALR 0 8.97378 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.19786 0 Q8TED9 AF1L1_HUMAN Actin filament-associated protein 1-like 1 (AFAP1-like protein 1) AFAP1L1 Homo sapiens (Human) anchoring junction [GO:0070161]; cell projection [GO:0042995]; cytosol [GO:0005829]; podosome [GO:0002102] SH3 domain binding [GO:0017124] 0.96919 -3.0587 AEEDARRYLVEK 0 0 0 0 0 0 0 9.06275 8.70228 11.4659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6079 Q8TEH3 DEN1A_HUMAN DENN domain-containing protein 1A (Connecdenn 1) (Connecdenn) (Protein FAM31A) DENND1A FAM31A KIAA1608 Homo sapiens (Human) endocytic recycling [GO:0032456]; endocytosis [GO:0006897]; protein transport [GO:0015031]; regulation of Rab protein signal transduction [GO:0032483] cell projection [GO:0042995]; clathrin-coated vesicle [GO:0030136]; clathrin-coated vesicle membrane [GO:0030665]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; presynaptic membrane [GO:0042734] guanyl-nucleotide exchange factor activity [GO:0005085]; phosphatidylinositol phosphate binding [GO:1901981]; phosphatidylinositol-3-phosphate binding [GO:0032266] 0.92746 -1.2029 SLEDLRAPK 0 11.4107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TEJ3 SH3R3_HUMAN E3 ubiquitin-protein ligase SH3RF3 (EC 2.3.2.27) (Plenty of SH3s 2) (SH3 domain-containing RING finger protein 3) (SH3 multiple domains protein 4) SH3RF3 POSH2 SH3MD4 Homo sapiens (Human) positive regulation of JNK cascade [GO:0046330]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630] 0.87268 0.030762 LLGASWLCASK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.9737 0 0 0 0 0 0 0 0 Q8TEK3 DOT1L_HUMAN "Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.360) (DOT1-like protein) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (Lysine N-methyltransferase 4)" DOT1L KIAA1814 KMT4 Homo sapiens (Human) DNA damage checkpoint signaling [GO:0000077]; DNA repair [GO:0006281]; gene expression [GO:0010467]; heterochromatin formation [GO:0031507]; histone H3-K79 methylation [GO:0034729]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; regulation of transcription regulatory region DNA binding [GO:2000677]; telomere organization [GO:0032200] cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] DNA binding [GO:0003677]; histone H3K79 methyltransferase activity [GO:0031151]; histone H3K79 trimethyltransferase activity [GO:0140956]; histone methyltransferase activity [GO:0042054]; nucleic acid binding [GO:0003676]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription coactivator activity [GO:0003713] 0.74207 0.32206 ALTYNDLIQAQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.94639 Q8TEL6 TP4AP_HUMAN Short transient receptor potential channel 4-associated protein (Trp4-associated protein) (Trpc4-associated protein) (Protein TAP1) (TNF-receptor ubiquitous scaffolding/signaling protein) (Protein TRUSS) TRPC4AP C20orf188 TRRP4AP Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; hair follicle maturation [GO:0048820]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] Cul4-RING E3 ubiquitin ligase complex [GO:0080008]; Cul4A-RING E3 ubiquitin ligase complex [GO:0031464]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] calcium channel activity [GO:0005262]; phosphatase binding [GO:0019902]; ubiquitin ligase-substrate adaptor activity [GO:1990756] 0.8703 0.053232 LLQSFSDHHENK 0 0 0 0 0 0 0 0 0 0 0 0 0 8.79058 0 9.94477 8.45816 0 9.4762 0 0 0 0 0 10.1589 8.97106 0 Q8TEM1 PO210_HUMAN Nuclear pore membrane glycoprotein 210 (Nuclear pore protein gp210) (Nuclear envelope pore membrane protein POM 210) (POM210) (Nucleoporin Nup210) (Pore membrane protein of 210 kDa) NUP210 KIAA0906 PSEC0245 Homo sapiens (Human) mRNA transport [GO:0051028]; nucleocytoplasmic transport [GO:0006913]; protein transport [GO:0015031] endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643] 0.9316 -1.2697 CDAIVDLIHDIQIVSTTR 0 9.37426 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.58976 0 0 0 0 0 10.3955 10.8816 0 0 0 Q8TEP8 CE192_HUMAN Centrosomal protein of 192 kDa (Cep192) (Cep192/SPD-2) CEP192 KIAA1569 PP8407 Homo sapiens (Human) centriole replication [GO:0007099]; centrosome-templated microtubule nucleation [GO:0090222]; mitotic spindle assembly [GO:0090307]; protein localization to centrosome [GO:0071539]; response to bacterium [GO:0009617] centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; pericentriolar material [GO:0000242]; procentriole [GO:0120098]; procentriole replication complex [GO:0120099] phosphatase binding [GO:0019902]; protein kinase binding [GO:0019901] 0.96954 -4.8234 AVGFKDSQK 9.01945 0 8.68036 0 0 0 0 8.75191 10.207 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.91648 0 0 0 Q8TEQ0 SNX29_HUMAN Sorting nexin-29 (RUN domain-containing protein 2A) SNX29 RUNDC2A Homo sapiens (Human) phosphatidylinositol binding [GO:0035091] 0.96722 -2.8616 AYNFPPK 9.13453 0 0 0 0 0 10.7855 0 0 0 0 0 0 0 0 10.7751 0 0 10.2717 0 0 0 0 0 0 0 0 Q8TEQ6 GEMI5_HUMAN Gem-associated protein 5 (Gemin5) GEMIN5 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; protein-containing complex assembly [GO:0065003]; regulation of translation [GO:0006417]; spliceosomal snRNP assembly [GO:0000387]; translation [GO:0006412]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; Gemini of coiled bodies [GO:0097504]; membrane [GO:0016020]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SMN complex [GO:0032797]; SMN-Gemin2 complex [GO:0034718]; SMN-Sm protein complex [GO:0034719] mRNA 3'-UTR binding [GO:0003730]; ribosome binding [GO:0043022]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; snRNA binding [GO:0017069]; U1 snRNA binding [GO:0030619]; U4 snRNA binding [GO:0030621]; U4atac snRNA binding [GO:0030622] 0.96263 -2.0834 GRGVMILKLPFLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.51865 0 0 10.4106 0 0 0 Q8TEQ8 PIGO_HUMAN GPI ethanolamine phosphate transferase 3 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class O protein) (PIG-O) PIGO UNQ632/PRO1249 Homo sapiens (Human) GPI anchor biosynthetic process [GO:0006506] endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] mannose-ethanolamine phosphotransferase activity [GO:0051377] 0.27486 0.83889 AFFFPSFNVR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1094 0 0 0 0 0 0 0 0 0 10.0668 0 0 0 Q8TER0 SNED1_HUMAN "Sushi, nidogen and EGF-like domain-containing protein 1 (Insulin-responsive sequence DNA-binding protein 1) (IRE-BP1)" SNED1 Homo sapiens (Human) cell-matrix adhesion [GO:0007160] extracellular matrix [GO:0031012]; extracellular region [GO:0005576] calcium ion binding [GO:0005509]; Notch binding [GO:0005112] 0.96376 -2.2468 AYNISVFSVKR 0 0 9.27687 0 0 12.3889 9.12609 8.87348 0 0 0 0 0 0 10.3386 0 0 0 0 0 0 0 0 0 0 0 0 Q8TER5 ARH40_HUMAN Rho guanine nucleotide exchange factor 40 (Protein SOLO) ARHGEF40 SOLO Homo sapiens (Human) axon guidance [GO:0007411]; regulation of small GTPase mediated signal transduction [GO:0051056] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; plasma membrane [GO:0005886] guanyl-nucleotide exchange factor activity [GO:0005085] 0.96827 -3.6515 RAPEPSAGTFQEMR 0 0 12.3028 0 13.017 0 10.7999 12.2226 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.39738 0 0 Q8TES7 FBF1_HUMAN Fas-binding factor 1 (FBF-1) (Protein albatross) FBF1 ALB KIAA1863 Homo sapiens (Human) apical junction assembly [GO:0043297]; cilium assembly [GO:0060271]; establishment of epithelial cell polarity [GO:0090162] anchoring junction [GO:0070161]; centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary transition fiber [GO:0097539]; cytosol [GO:0005829]; spindle pole [GO:0000922] 0.88629 -0.38993 EELLFDDGDDIMATLGFGDSPK 0 0 0 0 9.13535 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3679 0 0 Q8TET4 GANC_HUMAN Neutral alpha-glucosidase C (EC 3.2.1.20) GANC Homo sapiens (Human) N-glycan processing [GO:0006491] "alpha-1,4-glucosidase activity [GO:0004558]; carbohydrate binding [GO:0030246]; maltose alpha-glucosidase activity [GO:0032450]" 0.95417 -1.5135 QKQWLSK 0 0 9.77737 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TEU7 RPGF6_HUMAN Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2) RAPGEF6 PDZGEF2 Homo sapiens (Human) microvillus assembly [GO:0030033]; positive regulation of GTPase activity [GO:0043547]; protein localization to plasma membrane [GO:0072659]; Ras protein signal transduction [GO:0007265]; regulation of GTPase activity [GO:0043087] apical plasma membrane [GO:0016324]; centrosome [GO:0005813]; cytosol [GO:0005829]; endocytic vesicle [GO:0030139]; plasma membrane [GO:0005886] GTP-dependent protein binding [GO:0030742]; guanyl-nucleotide exchange factor activity [GO:0005085]; phosphatidic acid binding [GO:0070300]; small GTPase binding [GO:0031267] 0.96849 -3.3235 ELDRSGTR 0 0 0 0 0 8.72253 0 0 0 0 0 13.6295 0 0 8.83229 0 0 0 0 0 0 0 0 0 0 0 0 Q8TEU8 WFKN2_HUMAN "WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 (Growth and differentiation factor-associated serum protein 1) (GASP-1) (hGASP-1) (WAP, follistatin, immunoglobulin, Kunitz and NTR domain-containing-related protein) (WFIKKN-related protein)" WFIKKN2 GASP1 WFIKKNRP UNQ9235/PRO31996 Homo sapiens (Human) muscle cell development [GO:0055001]; negative regulation of DNA binding [GO:0043392]; negative regulation of peptidase activity [GO:0010466]; negative regulation of protein binding [GO:0032091]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; roof of mouth development [GO:0060021]; skeletal system development [GO:0001501]; transforming growth factor beta receptor signaling pathway [GO:0007179] extracellular space [GO:0005615] metalloendopeptidase inhibitor activity [GO:0008191]; receptor antagonist activity [GO:0048019]; serine-type endopeptidase inhibitor activity [GO:0004867]; transforming growth factor beta binding [GO:0050431] 0.89857 -0.63421 CYMDAEACSK 9.69846 9.8035 9.61591 0 0 0 0 0 0 9.19513 9.11187 0 0 0 0 0 0 0 0 0 0 0 0 11.16 0 0 0 Q8TEV8 SMCR5_HUMAN Smith-Magenis syndrome chromosomal region candidate gene 5 protein SMCR5 Homo sapiens (Human) 0.80129 0.23938 GQIHHSQTNEL 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.15074 0 0 0 0 Q8TEV9 SMCR8_HUMAN Guanine nucleotide exchange protein SMCR8 (Smith-Magenis syndrome chromosomal region candidate gene 8 protein) SMCR8 Homo sapiens (Human) autophagy [GO:0006914]; negative regulation of autophagosome assembly [GO:1902902]; negative regulation of exocytosis [GO:0045920]; negative regulation of gene expression [GO:0010629]; negative regulation of immune response [GO:0050777]; negative regulation of macroautophagy [GO:0016242]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of GTPase activity [GO:0043547]; positive regulation of TOR signaling [GO:0032008]; regulation of autophagy [GO:0010506]; regulation of TORC1 signaling [GO:1903432] Atg1/ULK1 kinase complex [GO:1990316]; cell projection [GO:0042995]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; guanyl-nucleotide exchange factor complex [GO:0032045]; nucleoplasm [GO:0005654]; postsynapse [GO:0098794]; presynapse [GO:0098793] GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; protein kinase binding [GO:0019901]; protein kinase inhibitor activity [GO:0004860] 0.96847 -3.8496 AGQNALK 13.4494 12.9508 12.9985 0 10.5194 0 13.5256 13.3472 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TEW0 PARD3_HUMAN Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha) PARD3 PAR3 PAR3A Homo sapiens (Human) asymmetric cell division [GO:0008356]; axonogenesis [GO:0007409]; bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; establishment of cell polarity [GO:0030010]; establishment of centrosome localization [GO:0051660]; establishment of epithelial cell polarity [GO:0090162]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; microtubule cytoskeleton organization [GO:0000226]; myelination in peripheral nervous system [GO:0022011]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; positive regulation of myelination [GO:0031643]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; protein localization [GO:0008104]; protein targeting to membrane [GO:0006612]; protein-containing complex assembly [GO:0065003] adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; internode region of axon [GO:0033269]; PAR polarity complex [GO:0120157]; plasma membrane [GO:0005886]; tight junction [GO:0070160] "phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]" 0.96921 -4.9401 AEHENLFR 0 0 0 0 0 0 0 0 0 0 8.75101 11.9906 12.9421 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TEW6 DOK4_HUMAN Docking protein 4 (Downstream of tyrosine kinase 4) (Insulin receptor substrate 5) (IRS-5) (IRS5) DOK4 Homo sapiens (Human) nervous system development [GO:0007399]; positive regulation of MAPK cascade [GO:0043410]; Ras protein signal transduction [GO:0007265]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] cytoplasm [GO:0005737]; cytosol [GO:0005829] 0.93861 -1.3202 FTFEAGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3717 0 0 10.0773 0 0 0 0 0 Q8TEW8 PAR3L_HUMAN Partitioning defective 3 homolog B (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 19 protein) (PAR3-beta) (Partitioning defective 3-like protein) (PAR3-L protein) PARD3B ALS2CR19 PAR3B PAR3L Homo sapiens (Human) cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; establishment of cell polarity [GO:0030010]; establishment of centrosome localization [GO:0051660]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; microtubule cytoskeleton organization [GO:0000226]; protein localization [GO:0008104] adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell cortex [GO:0005938]; cell junction [GO:0030054]; endomembrane system [GO:0012505]; protein-containing complex [GO:0032991] phosphatidylinositol binding [GO:0035091] 0.96777 -2.8955 DFGPTLGLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.90313 0 0 Q8TEX9 IPO4_HUMAN Importin-4 (Imp4) (Importin-4b) (Imp4b) (Ran-binding protein 4) (RanBP4) IPO4 IMP4B RANBP4 Homo sapiens (Human) protein import into nucleus [GO:0006606]; protein localization to nucleus [GO:0034504] chromatin [GO:0000785]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; small GTPase binding [GO:0031267] 0.88993 -0.50011 ELLLPDTER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2853 0 0 0 0 0 0 Q8TF01 PNISR_HUMAN "Arginine/serine-rich protein PNISR (PNN-interacting serine/arginine-rich protein) (SR-related protein) (SR-rich protein) (Serine/arginine-rich-splicing regulatory protein 130) (SRrp130) (Splicing factor, arginine/serine-rich 130) (Splicing factor, arginine/serine-rich 18)" PNISR C6orf111 SFRS18 SRRP130 HSPC261 HSPC306 Homo sapiens (Human) cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; presynaptic active zone [GO:0048786] RNA binding [GO:0003723] 0.96855 -6.5673 ERPSSFRDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.927 0 10.4143 0 0 0 9.1573 0 0 11.3136 0 0 Q8TF05 PP4R1_HUMAN Serine/threonine-protein phosphatase 4 regulatory subunit 1 PPP4R1 MEG1 PP4R1 Homo sapiens (Human) protein dephosphorylation [GO:0006470]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] protein phosphatase 4 complex [GO:0030289] protein phosphatase regulator activity [GO:0019888] 0.88191 -0.082272 FFQLCSDNVWGVRK 11.4031 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.67444 0 0 0 Q8TF17 S3TC2_HUMAN SH3 domain and tetratricopeptide repeat-containing protein 2 SH3TC2 KIAA1985 PP12494 Homo sapiens (Human) peripheral nervous system myelin maintenance [GO:0032287]; regulation of ERBB signaling pathway [GO:1901184]; regulation of intracellular protein transport [GO:0033157] cytoplasmic vesicle [GO:0031410]; plasma membrane [GO:0005886] 0.93219 -1.2752 ALCLILSK 0 0 0 0 0 0 0 0 0 0 10.6384 0 0 0 0 0 0 0 0 0 0 9.93873 0 0 0 0 0 Q8TF20 ZN721_HUMAN Zinc finger protein 721 ZNF721 KIAA1982 Homo sapiens (Human) nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96966 -5.933 AFRQSAILYVHR 12.5552 12.5476 0 0 0 0 9.30907 9.74162 13.0151 9.54977 14.168 13.1276 11.743 10.0898 12.2297 12.0329 12.2629 11.9558 0 0 0 0 0 10.2319 0 0 0 Q8TF30 WHAMM_HUMAN "WASP homolog-associated protein with actin, membranes and microtubules (WAS protein homology region 2 domain-containing protein 1) (WH2 domain-containing protein 1)" WHAMM KIAA1971 WHDC1 Homo sapiens (Human) actin filament organization [GO:0007015]; Arp2/3 complex-mediated actin nucleation [GO:0034314]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; focal adhesion assembly [GO:0048041]; lamellipodium assembly [GO:0030032]; plasma membrane tubulation [GO:0097320]; positive regulation of actin nucleation [GO:0051127] cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; Golgi membrane [GO:0000139]; microtubule [GO:0005874] actin binding [GO:0003779]; Arp2/3 complex binding [GO:0071933]; microtubule binding [GO:0008017]; small GTPase binding [GO:0031267] 0.88576 -0.38392 DQCKENHRFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1933 0 0 0 0 0 0 0 0 Q8TF32 ZN431_HUMAN Zinc finger protein 431 ZNF431 KIAA1969 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.29907 0.8109 DLWPEQDIK 0 0 0 0 0 0 0 0 0 9.41631 9.90531 0 0 0 0 0 0 0 9.59006 0 0 0 0 0 0 0 0 Q8TF39 ZN483_HUMAN Zinc finger protein 483 (Zinc finger protein with KRAB and SCAN domains 16) ZNF483 KIAA1962 ZKSCAN16 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.94828 -1.3697 DVAVNFSR 9.69213 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.95655 0 Q8TF40 FNIP1_HUMAN Folliculin-interacting protein 1 FNIP1 KIAA1961 Homo sapiens (Human) B cell apoptotic process [GO:0001783]; B cell differentiation [GO:0030183]; cellular response to starvation [GO:0009267]; immature B cell differentiation [GO:0002327]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of TOR signaling [GO:0032007]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of B cell apoptotic process [GO:0002904]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein-containing complex assembly [GO:0031334]; positive regulation of TOR signaling [GO:0032008]; regulation of pro-B cell differentiation [GO:2000973]; regulation of protein phosphorylation [GO:0001932]; TOR signaling [GO:0031929] cytoplasm [GO:0005737]; cytosol [GO:0005829]; lysosomal membrane [GO:0005765] ATPase inhibitor activity [GO:0042030]; enzyme binding [GO:0019899]; guanyl-nucleotide exchange factor activity [GO:0005085]; protein-folding chaperone binding [GO:0051087] 0.95982 -1.7266 DQCLKYQGSR 0 0 0 11.5641 0 0 0 0 0 0 0 0 0 0 0 0 0 9.81152 9.68815 0 0 0 0 0 9.73444 0 0 Q8TF42 UBS3B_HUMAN Ubiquitin-associated and SH3 domain-containing protein B (EC 3.1.3.48) (Cbl-interacting protein p70) (Suppressor of T-cell receptor signaling 1) (STS-1) (T-cell ubiquitin ligand 2) (TULA-2) (Tyrosine-protein phosphatase STS1/TULA2) UBASH3B KIAA1959 STS1 Homo sapiens (Human) collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; negative regulation of bone resorption [GO:0045779]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of signal transduction [GO:0009968]; peptidyl-tyrosine dephosphorylation [GO:0035335]; platelet aggregation [GO:0070527]; regulation of osteoclast differentiation [GO:0045670]; regulation of protein binding [GO:0043393]; regulation of release of sequestered calcium ion into cytosol [GO:0051279] cytoplasm [GO:0005737]; nucleus [GO:0005634] identical protein binding [GO:0042802]; phosphoprotein binding [GO:0051219]; protein tyrosine phosphatase activity [GO:0004725]; ubiquitin protein ligase binding [GO:0031625] 0.87619 -0.0069028 GLQQENHLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.16476 0 0 0 0 Q8TF44 C2C4C_HUMAN C2 calcium-dependent domain-containing protein 4C (Nuclear-localized factor 3) (Protein FAM148C) C2CD4C FAM148C KIAA1957 NLF3 Homo sapiens (Human) cytosol [GO:0005829] 0.60176 0.44118 APPEPGPESGQAR 0 0 0 0 0 0 0 0 0 0 9.83289 0 0 0 0 0 0 0 0 0 0 0 0 9.719 0 0 0 Q8TF46 DI3L1_HUMAN DIS3-like exonuclease 1 (EC 3.1.13.-) DIS3L DIS3L1 KIAA1955 Homo sapiens (Human) RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075] centrosome [GO:0005813]; cytoplasmic exosome (RNase complex) [GO:0000177]; cytosol [GO:0005829]; plasma membrane [GO:0005886] 3'-5'-RNA exonuclease activity [GO:0000175]; enzyme binding [GO:0019899]; RNA binding [GO:0003723] 0.82589 0.21354 DLALLDVSNNYGI 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3289 0 0 0 0 Q8TF47 ZFP90_HUMAN Zinc finger protein 90 homolog (Zfp-90) (Zinc finger protein 756) ZFP90 KIAA1954 ZNF756 Homo sapiens (Human) negative regulation of DNA binding [GO:0043392]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.96705 -2.7358 IHTRNKL 0 0 0 0 0 0 0 0 0 8.45759 0 8.67158 0 0 0 0 0 0 0 0 0 9.35837 9.40911 0 0 0 0 Q8TF61 FBX41_HUMAN F-box only protein 41 FBXO41 FBX41 KIAA1940 Homo sapiens (Human) cytosol [GO:0005829] 0.96938 -5.5785 EEYARSTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.56226 0 10.2666 0 0 0 0 0 0 0 0 0 Q8TF62 AT8B4_HUMAN Probable phospholipid-transporting ATPase IM (EC 7.6.2.1) (ATPase class I type 8B member 4) (P4-ATPase flippase complex alpha subunit ATP8B4) ATP8B4 KIAA1939 Homo sapiens (Human) Golgi organization [GO:0007030]; phospholipid translocation [GO:0045332] Golgi apparatus [GO:0005794]; phospholipid-translocating ATPase complex [GO:1990531]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; trans-Golgi network [GO:0005802] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled intramembrane lipid transporter activity [GO:0140326]; magnesium ion binding [GO:0000287] 0.96999 -5.3426 DATDDYFRHK 0 0 0 0 0 0 0 0 9.66993 0 0 0 0 0 0 0 0 0 0 9.34285 0 0 0 0 0 0 0 Q8TF63 DCNP1_HUMAN Dendritic cell nuclear protein 1 (Dendritic cell nuclear protein-1) (Dendritic cell-associated nuclear protein) DCANP1 C5orf20 DCNP1 Homo sapiens (Human) auditory behavior [GO:0031223]; cochlea development [GO:0090102]; cochlea morphogenesis [GO:0090103]; craniofacial suture morphogenesis [GO:0097094]; genitalia development [GO:0048806]; genitalia morphogenesis [GO:0035112]; hard palate morphogenesis [GO:1905748]; inner ear development [GO:0048839]; inner ear morphogenesis [GO:0042472]; learned vocalization behavior [GO:0098583]; mastication [GO:0071626]; negative regulation of relaxation of muscle [GO:1901078]; negative regulation of saliva secretion [GO:1905747]; neuromuscular process controlling balance [GO:0050885]; peristalsis [GO:0030432]; regulation of muscle organ development [GO:0048634]; thorax and anterior abdomen determination [GO:0007356]; trigeminal nerve development [GO:0021559]; vestibulocochlear nerve formation [GO:0021650] cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654] DNA binding [GO:0003677] 0.87179 0.048773 VSSSQQPPLHSLSSHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4822 0 0 0 0 0 0 0 0 Q8TF64 GIPC3_HUMAN PDZ domain-containing protein GIPC3 GIPC3 C19orf64 Homo sapiens (Human) 0.96114 -2.5603 MEGAAAR 0 0 8.23898 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TF65 GIPC2_HUMAN PDZ domain-containing protein GIPC2 GIPC2 Homo sapiens (Human) cytoplasm [GO:0005737]; extracellular exosome [GO:0070062] identical protein binding [GO:0042802] 0.87044 0.056521 DIDLATTMFEAGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.95973 0 0 0 0 0 0 0 0 0 0 0 Q8TF66 LRC15_HUMAN Leucine-rich repeat-containing protein 15 (Leucine-rich repeat protein induced by beta-amyloid homolog) (hLib) LRRC15 LIB Homo sapiens (Human) negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of cell migration [GO:0030335]; receptor-mediated virion attachment to host cell [GO:0046813] extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] collagen binding [GO:0005518]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236] 0.8414 0.17774 ELSPGIFGPMPNLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3691 Q8TF68 ZN384_HUMAN Zinc finger protein 384 (CAG repeat protein 1) (CAS-interacting zinc finger protein) (Nuclear matrix transcription factor 4) (Nuclear matrix protein 4) (Trinucleotide repeat-containing gene 1 protein) ZNF384 CAGH1 CIZ NMP4 TNRC1 Homo sapiens (Human) nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.94365 -1.3372 DGKTYRCR 0 0 0 0 0 0 0 0 0 9.2572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TF71 MOT10_HUMAN Monocarboxylate transporter 10 (MCT 10) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10) (T-type amino acid transporter 1) SLC16A10 MCT10 TAT1 Homo sapiens (Human) amino acid transport [GO:0006865]; aromatic amino acid transport [GO:0015801]; thyroid hormone generation [GO:0006590]; thyroid hormone transport [GO:0070327]; thyroid-stimulating hormone secretion [GO:0070460] basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886] amino acid transmembrane transporter activity [GO:0015171]; aromatic amino acid transmembrane transporter activity [GO:0015173]; L-phenylalanine transmembrane transporter activity [GO:0015192]; L-tryptophan transmembrane transporter activity [GO:0015196]; L-tyrosine transmembrane transporter activity [GO:0005302]; monocarboxylic acid transmembrane transporter activity [GO:0008028]; thyroid hormone transmembrane transporter activity [GO:0015349] 0.88318 -0.27051 EVVLMCIGVTSGVGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1297 0 0 0 0 0 0 11.1364 0 0 Q8TF72 SHRM3_HUMAN Protein Shroom3 (Shroom-related protein) (hShrmL) SHROOM3 KIAA1481 SHRML MSTP013 Homo sapiens (Human) actin filament organization [GO:0007015]; apical protein localization [GO:0045176]; cell morphogenesis [GO:0000902]; cellular pigment accumulation [GO:0043482]; pattern specification process [GO:0007389]; regulation of cell shape [GO:0008360] adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical plasma membrane [GO:0016324]; cortical actin cytoskeleton [GO:0030864]; cytoskeleton [GO:0005856]; microtubule [GO:0005874] actin filament binding [GO:0051015] 0.39471 0.7079 ELKENLDR 0 0 0 0 0 0 0 9.8305 0 9.7659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8TF74 WIPF2_HUMAN WAS/WASL-interacting protein family member 2 (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein) (WIP-related protein) WIPF2 WICH WIRE PP10631 Homo sapiens (Human) cytoskeleton [GO:0005856]; cytosol [GO:0005829] actin binding [GO:0003779] 0.80826 0.22921 GALLQDICK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0545 0 0 0 0 0 0 0 0 0 0 0 Q8WTQ1 D104A_HUMAN "Beta-defensin 104 (Beta-defensin 4) (BD-4) (DEFB-4) (hBD-4) (Defensin, beta 104)" DEFB104A DEFB104 DEFB4; DEFB104B Homo sapiens (Human) cellular response to phorbol 13-acetate 12-myristate [GO:1904628]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; monocyte chemotaxis [GO:0002548]; positive chemotaxis [GO:0050918] extracellular region [GO:0005576] chemoattractant activity [GO:0042056] 0.91529 -0.77074 IGRCPNTYACCLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2357 0 Q8WTQ4 CP078_HUMAN Uncharacterized protein C16orf78 C16orf78 Homo sapiens (Human) nucleus [GO:0005634] 0.93203 -1.257 GKGLMTAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.9641 11.9828 11.7417 0 0 0 0 0 0 11.8272 11.6343 11.8461 Q8WTQ7 GRK7_HUMAN Rhodopsin kinase GRK7 (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G protein-coupled receptor kinase GRK7) GRK7 GPRK7 Homo sapiens (Human) protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of signal transduction [GO:0009966]; signal transduction [GO:0007165]; visual perception [GO:0007601] cytoplasm [GO:0005737]; photoreceptor disc membrane [GO:0097381] ATP binding [GO:0005524]; rhodopsin kinase activity [GO:0050254] 0.92238 -1.0975 DFVTSAFYDKFLQWKLFEMQPVSDK 0 9.20545 0 0 0 0 0 10.3705 0 9.4172 12.1158 12.1447 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WTR7 ZN473_HUMAN Zinc finger protein 473 (Zinc finger protein 100 homolog) (Zfp-100) ZNF473 KIAA1141 ZFP100 Homo sapiens (Human) mRNA 3'-end processing by stem-loop binding and cleavage [GO:0006398] Cajal body [GO:0015030]; nucleoplasm [GO:0005654] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96967 -5.9389 HLIQHQK 0 10.5906 0 0 0 0 0 8.38901 0 0 0 0 0 0 0 0 0 0 0 10.78 0 0 0 0 0 0 0 Q8WTS1 ABHD5_HUMAN 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (EC 2.3.1.51) (Abhydrolase domain-containing protein 5) (Lipid droplet-binding protein CGI-58) ABHD5 NCIE2 CGI-58 Homo sapiens (Human) cell differentiation [GO:0030154]; fatty acid metabolic process [GO:0006631]; lipid homeostasis [GO:0055088]; negative regulation of sequestering of triglyceride [GO:0010891]; phosphatidic acid biosynthetic process [GO:0006654]; positive regulation of lipoprotein lipase activity [GO:0051006]; positive regulation of triglyceride catabolic process [GO:0010898] cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654] 1-acylglycerol-3-phosphate O-acyltransferase activity [GO:0003841]; carboxylic ester hydrolase activity [GO:0052689]; lysophosphatidic acid acyltransferase activity [GO:0042171] 0.9145 -0.83119 CVPCTYKK 0 0 11.5195 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WTT0 CLC4C_HUMAN C-type lectin domain family 4 member C (Blood dendritic cell antigen 2) (BDCA-2) (C-type lectin superfamily member 7) (Dendritic lectin) (CD antigen CD303) CLEC4C BDCA2 CLECSF11 CLECSF7 DLEC HECL UNQ9361/PRO34150 Homo sapiens (Human) adaptive immune response [GO:0002250]; antifungal innate immune response [GO:0061760] external side of plasma membrane [GO:0009897]; ficolin-1-rich granule membrane [GO:0101003]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; tertiary granule membrane [GO:0070821] carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872] 0.87204 0.02881 EYQQYHPSLTCVMEGK 0 0 0 9.16724 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WTV0 SCRB1_HUMAN "Scavenger receptor class B member 1 (SRB1) (CD36 and LIMPII analogous 1) (CLA-1) (CD36 antigen-like 1) (Collagen type I receptor, thrombospondin receptor-like 1) (SR-BI) (CD antigen CD36)" SCARB1 CD36L1 CLA1 Homo sapiens (Human) adhesion of symbiont to host [GO:0044406]; blood vessel endothelial cell migration [GO:0043534]; carotenoid transport [GO:0046867]; cholesterol catabolic process [GO:0006707]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol import [GO:0070508]; detection of lipopolysaccharide [GO:0032497]; endothelial cell proliferation [GO:0001935]; high-density lipoprotein particle clearance [GO:0034384]; high-density lipoprotein particle remodeling [GO:0034375]; intestinal lipid absorption [GO:0098856]; lipopolysaccharide transport [GO:0015920]; low-density lipoprotein particle clearance [GO:0034383]; phospholipid transport [GO:0015914]; plasma lipoprotein particle clearance [GO:0034381]; positive regulation of cholesterol storage [GO:0010886]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of triglyceride biosynthetic process [GO:0010867]; recognition of apoptotic cell [GO:0043654]; regulation of phagocytosis [GO:0050764]; regulation of phosphatidylcholine catabolic process [GO:0010899]; reverse cholesterol transport [GO:0043691]; triglyceride homeostasis [GO:0070328]; vitamin transmembrane transport [GO:0035461]; wound healing [GO:0042060] caveola [GO:0005901]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; endocytic vesicle membrane [GO:0030666]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; plasma membrane [GO:0005886] 1-phosphatidylinositol binding [GO:0005545]; amyloid-beta binding [GO:0001540]; apolipoprotein A-I binding [GO:0034186]; apolipoprotein binding [GO:0034185]; high-density lipoprotein particle binding [GO:0008035]; high-density lipoprotein particle receptor activity [GO:0070506]; lipid binding [GO:0008289]; lipopolysaccharide binding [GO:0001530]; lipopolysaccharide immune receptor activity [GO:0001875]; low-density lipoprotein particle binding [GO:0030169]; phosphatidylserine binding [GO:0001786]; scavenger receptor activity [GO:0005044]; virus receptor activity [GO:0001618] 0.91899 -0.89739 ERGPYVYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5669 0 0 0 0 0 0 0 0 0 Q8WTV1 THAP3_HUMAN THAP domain-containing protein 3 THAP3 Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.92317 -1.1543 SCAARQCCNRYSSR 0 0 0 0 0 0 12.4607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WTW3 COG1_HUMAN Conserved oligomeric Golgi complex subunit 1 (COG complex subunit 1) (Component of oligomeric Golgi complex 1) COG1 KIAA1381 LDLB Homo sapiens (Human) "glycosylation [GO:0070085]; Golgi organization [GO:0007030]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]; retrograde transport, vesicle recycling within Golgi [GO:0000301]" Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; trans-Golgi network membrane [GO:0032588] 0.93303 -1.2655 KEELRQMVGER 0 0 0 0 10.4446 0 10.4324 0 0 0 0 0 0 0 0 11.5621 0 0 0 0 0 0 0 0 0 0 0 Q8WTW4 NPRL2_HUMAN GATOR complex protein NPRL2 (Gene 21 protein) (G21 protein) (Nitrogen permease regulator 2-like protein) (NPR2-like protein) (Tumor suppressor candidate 4) NPRL2 TUSC4 Homo sapiens (Human) cellular response to amino acid starvation [GO:0034198]; negative regulation of kinase activity [GO:0033673]; negative regulation of TOR signaling [GO:0032007]; negative regulation of TORC1 signaling [GO:1904262]; positive regulation of autophagy [GO:0010508] GATOR1 complex [GO:1990130]; lysosomal membrane [GO:0005765]; vacuolar membrane [GO:0005774] GTPase activator activity [GO:0005096]; protein kinase activity [GO:0004672] 0.88591 -0.38384 IECIFFSEFHPTLGPK 0 0 0 0 0 0 11.3585 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WTX9 ZDHC1_HUMAN Palmitoyltransferase ZDHHC1 (EC 2.3.1.225) (DHHC domain-containing cysteine-rich protein 1) (Zinc finger DHHC domain-containing protein 1) (DHHC-1) (Zinc finger protein 377) ZDHHC1 C16orf1 ZNF377 Homo sapiens (Human) antiviral innate immune response [GO:0140374]; peptidyl-L-cysteine S-palmitoylation [GO:0018230]; positive regulation of defense response to virus by host [GO:0002230]; protein palmitoylation [GO:0018345]; protein targeting to membrane [GO:0006612] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794] DNA binding [GO:0003677]; palmitoyltransferase activity [GO:0016409]; protein-cysteine S-palmitoyltransferase activity [GO:0019706] 0.95106 -1.4137 GAGADSPR 0 0 0 0 0 0 0 0 0 0 0 0 8.29948 0 0 0 0 0 0 0 0 0 9.37221 0 0 0 0 Q8WTZ4 CA5BL_HUMAN Putative inactive carbonic anhydrase 5B-like protein (CA-VB-like protein) CA5BP1 CA5B CA5BL Homo sapiens (Human) cytoplasm [GO:0005737]; mitochondrion [GO:0005739] carbonate dehydratase activity [GO:0004089] 0.75821 0.30114 TTPPSWDYTRICIQR 0 0 0 0 10.3172 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WU17 RN139_HUMAN E3 ubiquitin-protein ligase RNF139 (EC 2.3.2.27) (RING finger protein 139) (RING-type E3 ubiquitin transferase RNF139) (Translocation in renal carcinoma on chromosome 8 protein) RNF139 TRC8 Homo sapiens (Human) endoplasmic reticulum mannose trimming [GO:1904380]; ERAD pathway [GO:0036503]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of translation [GO:0017148]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein destabilization [GO:0031648]; protein ubiquitination [GO:0016567]; regulation of ER to Golgi vesicle-mediated transport [GO:0060628]; regulation of protein processing [GO:0070613] Derlin-1 retrotranslocation complex [GO:0036513]; endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum quality control compartment [GO:0044322]; membrane [GO:0016020] protease binding [GO:0002020]; signaling receptor activity [GO:0038023]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-like protein transferase activity [GO:0019787]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.82964 0.21052 INSLPEIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.97039 0 Q8WU49 CG033_HUMAN Uncharacterized protein C7orf33 C7orf33 Homo sapiens (Human) 0.88398 -0.15171 GGPGQFNLSYATGR 0 0 0 0 0 10.3939 0 0 0 0 0 0 0 0 0 0 0 0 0 9.58543 0 0 0 10.4653 8.65539 0 8.69787 Q8WU58 F222B_HUMAN Protein FAM222B FAM222B C17orf63 Homo sapiens (Human) nucleoplasm [GO:0005654] 0.88054 0.013327 TVNGLDTSAQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.3014 0 0 0 0 0 0 0 0 0 0 Q8WU66 TSEAR_HUMAN Thrombospondin-type laminin G domain and EAR repeat-containing protein (TSP-EAR) TSPEAR C21orf29 Homo sapiens (Human) hair cycle process [GO:0022405]; Notch signaling pathway [GO:0007219]; regulation of Notch signaling pathway [GO:0008593]; sensory perception of sound [GO:0007605]; signal transduction [GO:0007165]; tooth mineralization [GO:0034505] cell surface [GO:0009986]; ciliary membrane [GO:0060170]; extracellular region [GO:0005576]; stereocilium [GO:0032420] 0.7126 0.3674 GLFMGLVR 0 0 9.48923 0 0 0 0 0 0 0 0 0 0 0 0 0 9.02453 0 0 0 0 0 0 0 0 0 0 Q8WU68 U2AF4_HUMAN Splicing factor U2AF 26 kDa subunit (U2 auxiliary factor 26) (U2 small nuclear RNA auxiliary factor 1-like protein 4) (U2AF1-like 4) (U2(RNU2) small nuclear RNA auxiliary factor 1-like protein 3) (U2 small nuclear RNA auxiliary factor 1-like protein 3) (U2AF1-like protein 3) U2AF1L4 U2AF1-RS3 U2AF1L3 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]" cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U2AF complex [GO:0089701] metal ion binding [GO:0046872]; pre-mRNA 3'-splice site binding [GO:0030628] 0.96692 -2.8259 DKVNCSFYFK 0 0 0 0 0 0 0 0 0 0 0 10.5473 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WU79 SMAP2_HUMAN Stromal membrane-associated protein 2 (Stromal membrane-associated protein 1-like) SMAP2 SMAP1L Homo sapiens (Human) cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654] GTPase activator activity [GO:0005096]; metal ion binding [GO:0046872] 0.88486 -0.12788 NLGVHISRVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.64053 8.60585 0 0 0 0 0 0 0 0 0 0 Q8WU90 ZC3HF_HUMAN Zinc finger CCCH domain-containing protein 15 (DRG family-regulatory protein 1) (Likely ortholog of mouse immediate early response erythropoietin 4) ZC3H15 DFRP1 LEREPO4 HSPC303 HT010 MSTP012 PP730 Homo sapiens (Human) cytokine-mediated signaling pathway [GO:0019221]; cytoplasmic translation [GO:0002181]; positive regulation of GTPase activity [GO:0043547] cytosol [GO:0005829]; nucleus [GO:0005634] cadherin binding [GO:0045296]; metal ion binding [GO:0046872]; RNA binding [GO:0003723] 0.91475 -0.81092 AVTHQVKFGQQNPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2842 0 0 0 0 0 0 0 0 0 0 0 Q8WUA2 PPIL4_HUMAN Peptidyl-prolyl cis-trans isomerase-like 4 (PPIase) (EC 5.2.1.8) (Cyclophilin-like protein PPIL4) (Rotamase PPIL4) PPIL4 Homo sapiens (Human) protein peptidyl-prolyl isomerization [GO:0000413] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723] 0.96437 -2.3833 EQLDSGR 0 0 0 0 0 0 0 11.9326 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.48732 0 0 0 Q8WUA7 TB22A_HUMAN TBC1 domain family member 22A TBC1D22A C22orf4 Homo sapiens (Human) activation of GTPase activity [GO:0090630] 14-3-3 protein binding [GO:0071889]; GTPase activator activity [GO:0005096]; protein homodimerization activity [GO:0042803] 0.96912 -3.3761 YLQFAFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.98797 0 0 0 0 0 0 0 0 0 0 Q8WUB8 PHF10_HUMAN PHD finger protein 10 (BRG1-associated factor 45a) (BAF45a) (XAP135) PHF10 BAF45A Homo sapiens (Human) chromatin remodeling [GO:0006338]; nervous system development [GO:0007399]; positive regulation of cell differentiation [GO:0045597]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of T cell differentiation [GO:0045582]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; kinetochore [GO:0000776]; npBAF complex [GO:0071564]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; RSC-type complex [GO:0016586]; SWI/SNF complex [GO:0016514] metal ion binding [GO:0046872] 0.89038 -0.45846 ERQRITDHYK 0 0 0 0 10.4157 0 0 0 0 0 0 10.5517 0 8.95553 0 0 0 8.76825 0 8.68923 0 0 0 0 0 0 0 Q8WUD4 CCD12_HUMAN Coiled-coil domain-containing protein 12 CCDC12 Homo sapiens (Human) nucleoplasm [GO:0005654]; post-mRNA release spliceosomal complex [GO:0071014]; U2-type spliceosomal complex [GO:0005684] 0.9641 -2.2772 RVPQAKPVAVEEKVK 0 0 0 0 0 0 0 10.6054 0 0 9.0091 9.08084 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WUF5 IASPP_HUMAN RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (NFkB-interacting protein 1) (PPP1R13B-like protein) PPP1R13L IASPP NKIP1 PPP1R13BL RAI Homo sapiens (Human) apoptotic process [GO:0006915]; cardiac muscle contraction [GO:0060048]; cardiac right ventricle morphogenesis [GO:0003215]; embryonic camera-type eye development [GO:0031076]; hair cycle [GO:0042633]; multicellular organism growth [GO:0035264]; multicellular organismal-level homeostasis [GO:0048871]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell differentiation [GO:0045597]; post-embryonic development [GO:0009791]; regulation of transcription by RNA polymerase II [GO:0006357]; ventricular cardiac muscle tissue development [GO:0003229] cell junction [GO:0030054]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; transcription corepressor activity [GO:0003714] 0.91505 -0.79606 SDAGSYRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.26852 0 0 0 0 Q8WUF8 F172A_HUMAN Cotranscriptional regulator FAM172A (Protein FAM172A) FAM172A C5orf21 Homo sapiens (Human) "mRNA processing [GO:0006397]; neural crest cell development [GO:0014032]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]; small ncRNA-mediated heterochromatin formation [GO:0031048]" endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634] 0.9696 -3.54 IDLDELMKK 0 0 0 0 0 0 0 0 0 9.96679 9.97599 0 0 0 0 0 0 0 0 0 0 8.79763 0 0 0 0 9.65834 Q8WUH2 TGFA1_HUMAN Transforming growth factor-beta receptor-associated protein 1 (TGF-beta receptor-associated protein 1) (TRAP-1) (TRAP1) TGFBRAP1 Homo sapiens (Human) autophagy [GO:0006914]; endosomal vesicle fusion [GO:0034058]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; regulation of DNA-templated transcription [GO:0006355]; regulation of SNARE complex assembly [GO:0035542]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179] CORVET complex [GO:0033263]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020] SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160] 0.81682 0.22072 TMQVALGLAR 0 0 0 0 11.0156 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WUH6 TM263_HUMAN Transmembrane protein 263 TMEM263 C12orf23 Homo sapiens (Human) membrane [GO:0016020] 0.82528 0.2126 GAVGATIGGVAWIGGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.07767 0 0 0 0 0 0 0 0 0 0 Q8WUI4 HDAC7_HUMAN Histone deacetylase 7 (HD7) (EC 3.5.1.98) (Histone deacetylase 7A) (HD7a) HDAC7 HDAC7A Homo sapiens (Human) cell-cell junction assembly [GO:0007043]; histone deacetylation [GO:0016575]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; protein deacetylation [GO:0006476]; protein sumoylation [GO:0016925]; vasculogenesis [GO:0001570] cytoplasm [GO:0005737]; cytosol [GO:0005829]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 14-3-3 protein binding [GO:0071889]; chromatin binding [GO:0003682]; DNA-binding transcription factor binding [GO:0140297]; histone deacetylase activity [GO:0004407]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; protein kinase C binding [GO:0005080]; protein lysine deacetylase activity [GO:0033558]; SUMO transferase activity [GO:0019789]; transcription corepressor activity [GO:0003714] 0.8497 0.11256 HPEHAGRIQSIWSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.49273 0 0 0 0 0 0 Q8WUJ3 CEMIP_HUMAN Cell migration-inducing and hyaluronan-binding protein (EC 3.2.1.35) CEMIP KIAA1199 Homo sapiens (Human) hyaluronan biosynthetic process [GO:0030213]; hyaluronan catabolic process [GO:0030214]; positive regulation of cell migration [GO:0030335]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; sensory perception of sound [GO:0007605] clathrin-coated endocytic vesicle [GO:0045334]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; fibrillar center [GO:0001650]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886] clathrin heavy chain binding [GO:0032050]; ER retention sequence binding [GO:0046923]; hyaluronic acid binding [GO:0005540]; hyalurononglucosaminidase activity [GO:0004415] 0.96766 -3.7188 DHFLEVKMESSK 0 12.1792 0 0 9.11751 0 0 0 0 0 0 0 0 0 0 0 11.7235 0 0 0 0 8.71246 0 0 0 0 0 Q8WUK0 PTPM1_HUMAN "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 (EC 3.1.3.27) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase) (Protein-tyrosine phosphatase mitochondrial 1) (EC 3.1.3.16, EC 3.1.3.48)" PTPMT1 MOSP PLIP PNAS-129 Homo sapiens (Human) cardiolipin biosynthetic process [GO:0032049]; protein dephosphorylation [GO:0006470]; regulation of intrinsic apoptotic signaling pathway [GO:2001242] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; nucleus [GO:0005634] "myosin phosphatase activity [GO:0017018]; phosphatidylglycerophosphatase activity [GO:0008962]; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity [GO:0004439]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]" 0.88363 -0.049438 VPGRAHRDWYHR 0 11.3006 11.2856 0 0 0 11.2796 0 0 0 0 0 0 0 10.3681 0 0 0 0 0 0 0 0 0 0 0 0 Q8WUM0 NU133_HUMAN Nuclear pore complex protein Nup133 (133 kDa nucleoporin) (Nucleoporin Nup133) NUP133 Homo sapiens (Human) mRNA export from nucleus [GO:0006406]; nephron development [GO:0072006]; neural tube development [GO:0021915]; neurogenesis [GO:0022008]; nuclear pore organization [GO:0006999]; nucleocytoplasmic transport [GO:0006913]; paraxial mesoderm development [GO:0048339]; poly(A)+ mRNA export from nucleus [GO:0016973]; protein import into nucleus [GO:0006606]; somite development [GO:0061053]; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000972] cytosol [GO:0005829]; kinetochore [GO:0000776]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear pore outer ring [GO:0031080] structural constituent of nuclear pore [GO:0017056] 0.92207 -1.1355 NSLYRREESLEK 0 8.82899 0 0 0 0 8.80826 0 0 0 0 9.20112 0 0 0 9.78629 0 9.05983 0 0 0 9.19535 0 8.81929 0 0 0 Q8WUM4 PDC6I_HUMAN Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (ALG-2-interacting protein X) (Hp95) PDCD6IP AIP1 ALIX KIAA1375 Homo sapiens (Human) actomyosin contractile ring assembly [GO:0000915]; apoptotic process [GO:0006915]; bicellular tight junction assembly [GO:0070830]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; midbody abscission [GO:0061952]; mitotic cytokinesis [GO:0000281]; multivesicular body assembly [GO:0036258]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]; regulation of centrosome duplication [GO:0010824]; regulation of extracellular exosome assembly [GO:1903551]; regulation of membrane permeability [GO:0090559]; ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway [GO:0090611]; viral budding [GO:0046755]; viral budding via host ESCRT complex [GO:0039702] actomyosin [GO:0042641]; bicellular tight junction [GO:0005923]; cytosol [GO:0005829]; endoplasmic reticulum exit site [GO:0070971]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular vesicle [GO:1903561]; Flemming body [GO:0090543]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; melanosome [GO:0042470]; membrane [GO:0016020]; microtubule organizing center [GO:0005815] calcium-dependent protein binding [GO:0048306]; protein homodimerization activity [GO:0042803]; proteinase activated receptor binding [GO:0031871] 0.84144 0.17935 DNDFIYHDR 0 0 0 0 0 0 0 0 0 0 0 12.5182 0 0 0 0 0 0 0 10.2829 0 0 0 0 0 12.8864 0 Q8WUM9 S20A1_HUMAN Sodium-dependent phosphate transporter 1 (Gibbon ape leukemia virus receptor 1) (GLVR-1) (Leukemia virus receptor 1 homolog) (Phosphate transporter 1) (PiT-1) (Solute carrier family 20 member 1) SLC20A1 GLVR1 PIT1 Homo sapiens (Human) biomineral tissue development [GO:0031214]; cell population proliferation [GO:0008283]; monoatomic ion transport [GO:0006811]; phosphate ion transmembrane transport [GO:0035435]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123] membrane [GO:0016020]; plasma membrane [GO:0005886] high-affinity inorganic phosphate:sodium symporter activity [GO:0005316]; inorganic phosphate transmembrane transporter activity [GO:0005315]; signaling receptor activity [GO:0038023]; sodium:phosphate symporter activity [GO:0005436] 0.96352 -2.1125 LTWPNADSKKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.178 0 0 0 0 0 0 0 0 0 0 Q8WUQ7 CATIN_HUMAN Splicing factor Cactin (Renal carcinoma antigen NY-REN-24) CACTIN C19orf29 Homo sapiens (Human) "cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; innate immune response [GO:0045087]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]" catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681] RNA binding [GO:0003723] 0.88357 -0.046029 HGFRCQFANGIFQLWFHFK 0 10.9071 0 0 0 0 10.5496 0 0 0 0 0 0 0 0 10.917 0 0 0 0 0 0 0 9.03306 0 0 0 Q8WUR7 CO040_HUMAN UPF0235 protein C15orf40 C15orf40 Homo sapiens (Human) cytoplasm [GO:0005737] 0.85053 0.16041 LLCAEMPK 0 0 0 0 0 0 0 0 0 0 11.5543 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WUU4 ZN296_HUMAN Zinc finger protein 296 (ZFP296) (Zinc finger protein 342) ZNF296 ZNF342 Homo sapiens (Human) negative regulation of dendrite development [GO:2000171]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283] nucleus [GO:0005634] DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837] 0.84575 0.1745 LGCQLFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.61162 0 Q8WUW1 BRK1_HUMAN Protein BRICK1 (BRK1) BRK1 C3orf10 HSPC300 MDS027 Homo sapiens (Human) actin filament organization [GO:0007015]; cell motility [GO:0048870]; fibroblast proliferation [GO:0048144]; in utero embryonic development [GO:0001701]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of protein-containing complex assembly [GO:0031334]; Rac protein signal transduction [GO:0016601]; regulation of actin polymerization or depolymerization [GO:0008064] cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lamellipodium [GO:0030027]; SCAR complex [GO:0031209] identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877] 0.87801 -0.0051708 EIHQDWANR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.7241 0 0 0 0 0 0 0 0 Q8WUX2 CHAC2_HUMAN Glutathione-specific gamma-glutamylcyclotransferase 2 (Gamma-GCG 2) (EC 4.3.2.7) (Cation transport regulator-like protein 2) CHAC2 Homo sapiens (Human) glutathione biosynthetic process [GO:0006750]; glutathione catabolic process [GO:0006751] cytoplasm [GO:0005737]; cytosol [GO:0005829] gamma-glutamylcyclotransferase activity [GO:0003839]; glutathione specific gamma-glutamylcyclotransferase activity [GO:0061928] 0.96043 -1.9892 EKGGYRTTTVIFYPK 11.1032 0 0 0 0 0 0 0 0 12.1944 0 12.6631 0 11.2851 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WUY3 PRUN2_HUMAN Protein prune homolog 2 (BNIP2 motif-containing molecule at the C-terminal region 1) PRUNE2 BMCC1 BNIPXL C9orf65 KIAA0367 Homo sapiens (Human) apoptotic process [GO:0006915] cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] metal ion binding [GO:0046872]; pyrophosphatase activity [GO:0016462] 0.96814 -3.6282 CYQMIDR 15.4124 15.2832 15.2874 12.0501 0 12.3763 14.625 14.7207 14.5785 0 0 14.6223 0 0 13.4537 14.2396 0 0 0 0 0 0 0 0 0 0 0 Q8WUY9 DEP1B_HUMAN DEP domain-containing protein 1B (HBV X-transactivated gene 8 protein) (HBV XAg-transactivated protein 8) DEPDC1B XTP8 Homo sapiens (Human) cell migration [GO:0016477]; intracellular signal transduction [GO:0035556]; positive regulation of Wnt signaling pathway [GO:0030177] GTPase activator activity [GO:0005096] 0.80876 0.22733 CSQNFGPEVTR 0 0 0 0 0 0 9.373 0 0 9.56759 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WUZ0 BCL7C_HUMAN B-cell CLL/lymphoma 7 protein family member C BCL7C Homo sapiens (Human) apoptotic process [GO:0006915]; chromatin remodeling [GO:0006338]; negative regulation of cell differentiation [GO:0045596]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of stem cell population maintenance [GO:1902459]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; GBAF complex [GO:0140288]; SWI/SNF complex [GO:0016514] 0.88352 -0.26624 MAGRTVR 12.2136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WV16 DCAF4_HUMAN DDB1- and CUL4-associated factor 4 (WD repeat-containing protein 21A) DCAF4 WDR21 WDR21A Homo sapiens (Human) protein ubiquitination [GO:0016567] Cul4-RING E3 ubiquitin ligase complex [GO:0080008]; nucleoplasm [GO:0005654] 0.92526 -0.97656 LRDSEDRSDSR 0 0 0 0 0 0 0 0 10.0684 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WV28 BLNK_HUMAN B-cell linker protein (B-cell adapter containing a SH2 domain protein) (B-cell adapter containing a Src homology 2 domain protein) (Cytoplasmic adapter protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65) BLNK BASH SLP65 Homo sapiens (Human) B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; positive regulation of gene expression [GO:0010628]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; plasma membrane [GO:0005886] enzyme binding [GO:0019899]; lipid binding [GO:0008289]; phospholipase binding [GO:0043274]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; SH2 domain binding [GO:0042169]; signaling adaptor activity [GO:0035591]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068] 0.47124 0.63102 HSPPFSK 10.5236 0 0 0 0 0 0 0 0 9.02639 8.99325 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WV41 SNX33_HUMAN Sorting nexin-33 (SH3 and PX domain-containing protein 3) SNX33 SH3PX3 SH3PXD3C SNX30 Homo sapiens (Human) cleavage furrow formation [GO:0036089]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; intracellular protein transport [GO:0006886]; macropinocytosis [GO:0044351]; mitotic cytokinesis [GO:0000281]; negative regulation of endocytosis [GO:0045806]; negative regulation of protein localization to cell surface [GO:2000009]; plasma membrane tubulation [GO:0097320]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of protein localization to cell surface [GO:2000010]; protein import [GO:0017038] cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; plasma membrane [GO:0005886] identical protein binding [GO:0042802]; phosphatidylinositol binding [GO:0035091] 0.86976 0.065936 ESQRMSDEGR 0 0 0 0 0 0 0 0 0 8.32328 0 0 0 0 0 0 9.30882 0 0 0 0 0 0 0 0 0 0 Q8WV44 TRI41_HUMAN E3 ubiquitin-protein ligase TRIM41 (EC 2.3.2.27) (RING finger-interacting protein with C kinase) (RINCK) (Tripartite motif-containing protein 41) TRIM41 RINCK Homo sapiens (Human) cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; defense response to virus [GO:0051607]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567] cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleolus [GO:0005730] identical protein binding [GO:0042802]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.92451 -0.98739 AGAAASR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.05009 0 0 9.64283 0 8.49809 0 0 9.18908 0 0 0 0 Q8WV60 PTCD2_HUMAN "Pentatricopeptide repeat-containing protein 2, mitochondrial" PTCD2 Homo sapiens (Human) kidney development [GO:0001822]; liver development [GO:0001889]; mitochondrion organization [GO:0007005]; mRNA processing [GO:0006397]; muscle cell development [GO:0055001]; regulation of gene expression [GO:0010468]; regulation of mRNA processing [GO:0050684]; ventricular cardiac muscle tissue morphogenesis [GO:0055010] mitochondrion [GO:0005739] RNA binding [GO:0003723] 0.049145 1.4444 GELITLLHLCESR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.34 0 0 0 0 0 0 0 0 0 0 0 0 Q8WV74 NUDT8_HUMAN Mitochondrial coenzyme A diphosphatase NUDT8 (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 8) (Nudix motif 8) NUDT8 Homo sapiens (Human) acetyl-CoA catabolic process [GO:0046356]; butyryl-CoA catabolic process [GO:0044580]; coenzyme A catabolic process [GO:0015938]; malonyl-CoA catabolic process [GO:2001294]; medium-chain fatty-acyl-CoA catabolic process [GO:0036114]; propionyl-CoA catabolic process [GO:1902859]; succinyl-CoA catabolic process [GO:1901289] mitochondrion [GO:0005739] acyl-coenzyme A diphosphatase activity [GO:0106399]; CoA pyrophosphatase activity [GO:0010945]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145] 0.94633 -1.3517 LPDCLSAEGELRCRR 0 0 0 0 0 0 0 0 0 0 0 9.52142 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WV83 S35F5_HUMAN Solute carrier family 35 member F5 (Hepatitis C virus NS5A-transactivated protein 3) (HCV NS5A-transactivated protein 3) SLC35F5 NS5ATP3 UNQ2545/PRO6097 Homo sapiens (Human) membrane [GO:0016020] 0.8213 0.2179 FSNIMEIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6411 0 0 Q8WV92 MITD1_HUMAN MIT domain-containing protein 1 MITD1 Homo sapiens (Human) midbody abscission [GO:0061952]; mitotic cytokinesis [GO:0000281]; negative regulation of protein binding [GO:0032091] extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; midbody [GO:0030496] identical protein binding [GO:0042802]; phosphatidylinositol binding [GO:0035091]; protein domain specific binding [GO:0019904] 0.8834 -0.087354 GLDYFKKPQSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.39322 0 0 0 0 10.6523 0 Q8WV93 AFG1L_HUMAN AFG1-like ATPase (Lactation elevated protein 1) (EC 3.6.-.-) (Protein AFG1 homolog) AFG1L AFG1 LACE1 Homo sapiens (Human) "mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial protein catabolic process [GO:0035694]; mitochondrion organization [GO:0007005]" cytoplasm [GO:0005737]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887] 0.78225 0.25244 LFDELAQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.54743 0 0 0 0 0 0 0 0 0 0 Q8WV99 ZFN2B_HUMAN AN1-type zinc finger protein 2B (Arsenite-inducible RNA-associated protein-like protein) (AIRAP-like protein) ZFAND2B AIRAPL Homo sapiens (Human) "proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein targeting to ER [GO:0045047]; regulation of insulin-like growth factor receptor signaling pathway [GO:0043567]; SRP-dependent cotranslational protein targeting to membrane, translocation [GO:0006616]" cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; proteasome complex [GO:0000502] K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; ubiquitin binding [GO:0043130]; zinc ion binding [GO:0008270] 0.7088 0.36875 CSRNFCIKHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.28762 0 0 0 0 0 Q8WVB3 HEXD_HUMAN Hexosaminidase D (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (Beta-hexosaminidase D) (Hexosaminidase domain-containing protein) (N-acetyl-beta-galactosaminidase) HEXD HEXDC Homo sapiens (Human) carbohydrate metabolic process [GO:0005975] cytoplasm [GO:0005737]; extracellular vesicle [GO:1903561]; nucleus [GO:0005634] beta-N-acetylhexosaminidase activity [GO:0004563]; hexosaminidase activity [GO:0015929]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148] 0.96174 -2.5603 AVASGVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.99633 0 0 0 0 0 0 0 0 0 Q8WVC0 LEO1_HUMAN RNA polymerase-associated protein LEO1 (Replicative senescence down-regulated leo1-like protein) LEO1 RDL Homo sapiens (Human) endodermal cell fate commitment [GO:0001711]; histone modification [GO:0016570]; mRNA polyadenylation [GO:0006378]; negative regulation of myeloid cell differentiation [GO:0045638]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; stem cell population maintenance [GO:0019827]; transcription elongation by RNA polymerase II [GO:0006368]; Wnt signaling pathway [GO:0016055] Cdc73/Paf1 complex [GO:0016593]; centrosome [GO:0005813]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] RNA polymerase II C-terminal domain phosphoserine binding [GO:1990269] 0.92721 -1.192 IYSSDSDEGSEEDK 0 0 10.2677 0 0 0 9.96404 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4015 0 0 0 0 Q8WVE0 EFMT1_HUMAN EEF1A lysine methyltransferase 1 (EC 2.1.1.-) (N(6)-adenine-specific DNA methyltransferase 2) (Protein-lysine N-methyltransferase N6AMT2) (eEF1A-KMT) EEF1AKMT1 N6AMT2 Homo sapiens (Human) peptidyl-lysine methylation [GO:0018022]; protein methylation [GO:0006479] cytosol [GO:0005829] histone methyltransferase activity [GO:0042054]; methyltransferase activity [GO:0008168]; nucleic acid binding [GO:0003676]; protein-lysine N-methyltransferase activity [GO:0016279] 0.0061538 2.6765 CYVNYDSGLDCGI 16.6035 16.4834 15.7673 15.3103 15.318 14.9953 15.2037 15.3727 15.1789 0 0 0 13.1727 13.4684 13.3779 14.193 13.802 12.5317 10.4912 10.4908 10.8436 11.3044 10.7681 10.8203 10.807 10.326 9.88856 Q8WVF1 OSCP1_HUMAN Protein OSCP1 (hOSCP1) (Organic solute transport protein 1) (Oxidored-nitro domain-containing protein 1) OSCP1 C1orf102 NOR1 Homo sapiens (Human) xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961] basal plasma membrane [GO:0009925]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886] transmembrane transporter activity [GO:0022857] 0.93037 -1.2477 AQNIPGDKAR 0 0 0 0 0 0 0 0 0 9.47013 0 0 0 0 0 0 0 0 0 0 0 0 9.08337 0 0 0 0 Q8WVI0 UQCC5_HUMAN Ubiquinol-cytochrome-c reductase complex assembly factor 5 (Small integral membrane protein 4) UQCC5 C3orf78 SMIM4 Homo sapiens (Human) mitochondrial cytochrome c oxidase assembly [GO:0033617]; mitochondrial respiratory chain complex III assembly [GO:0034551] mitochondrial inner membrane [GO:0005743] mitochondrial ribosome binding [GO:0097177] 0.96768 -2.9388 FTRAQVR 0 0 0 0 0 0 0 0 0 0 0 10.3607 0 0 0 0 0 0 0 0 0 0 0 0 10.2576 0 10.2511 Q8WVK2 SNR27_HUMAN U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein (U4/U6.U5 snRNP 27 kDa protein) (U4/U6.U5-27K) (Nucleic acid-binding protein RY-1) (U4/U6.U5 tri-snRNP-associated 27 kDa protein) (27K) (U4/U6.U5 tri-snRNP-associated protein 3) SNRNP27 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]" nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U4/U6 x U5 tri-snRNP complex [GO:0046540] nucleic acid binding [GO:0003676] 0.81917 0.2192 QITEEDLEGK 0 0 0 0 9.44323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.067 Q8WVK7 SKA2_HUMAN Spindle and kinetochore-associated protein 2 (Protein FAM33A) SKA2 FAM33A Homo sapiens (Human) cell division [GO:0051301]; chromosome segregation [GO:0007059]; mitotic cell cycle [GO:0000278]; regulation of microtubule polymerization or depolymerization [GO:0031110] cytosol [GO:0005829]; kinetochore [GO:0000776]; outer kinetochore [GO:0000940]; spindle microtubule [GO:0005876] microtubule binding [GO:0008017] 0.91479 -0.78092 EAEVDKLELMFQK 0 0 0 0 0 0 0 0 10.2188 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WVM0 TFB1M_HUMAN "Dimethyladenosine transferase 1, mitochondrial (EC 2.1.1.-) (Mitochondrial 12S rRNA dimethylase 1) (Mitochondrial transcription factor B1) (h-mtTFB) (h-mtTFB1) (hTFB1M) (mtTFB1) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1)" TFB1M CGI-75 Homo sapiens (Human) rRNA methylation [GO:0031167]; rRNA modification [GO:0000154]; transcription initiation at mitochondrial promoter [GO:0006391] mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645] "DNA binding [GO:0003677]; mitochondrial transcription factor activity [GO:0034246]; RNA binding [GO:0003723]; rRNA (adenine-N6,N6-)-dimethyltransferase activity [GO:0000179]" 0.96388 -2.42 EVAERLAANTGSKQR 0 0 0 0 0 0 0 0 0 0 11.2746 0 0 0 0 13.811 0 0 0 0 0 0 0 0 0 10.6434 0 Q8WVM7 STAG1_HUMAN Cohesin subunit SA-1 (SCC3 homolog 1) (Stromal antigen 1) STAG1 SA1 SCC3 Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic sister chromatid cohesion [GO:0034087]; localization [GO:0051179]; mitotic spindle assembly [GO:0090307]; sister chromatid cohesion [GO:0007062] "chromatin [GO:0000785]; chromosome [GO:0005694]; chromosome, centromeric region [GO:0000775]; cohesin complex [GO:0008278]; cytosol [GO:0005829]; mitotic spindle pole [GO:0097431]; nuclear body [GO:0016604]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]" chromatin binding [GO:0003682] 0.94008 -1.3069 KPRKSPGEK 0 0 0 0 0 0 0 0 0 0 0 8.20633 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WVM8 SCFD1_HUMAN Sec1 family domain-containing protein 1 (SLY1 homolog) (Sly1p) (Syntaxin-binding protein 1-like 2) SCFD1 C14orf163 KIAA0917 STXBP1L2 FKSG23 Homo sapiens (Human) "cell morphogenesis [GO:0000902]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; negative regulation of autophagosome assembly [GO:1902902]; post-Golgi vesicle-mediated transport [GO:0006892]; regulation of ER to Golgi vesicle-mediated transport [GO:0060628]; regulation of protein transport [GO:0051223]; response to hypoxia [GO:0001666]; response to toxic substance [GO:0009636]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; toxin transport [GO:1901998]" cis-Golgi network [GO:0005801]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi-associated vesicle [GO:0005798]; plasma membrane [GO:0005886] protein-containing complex binding [GO:0044877]; syntaxin binding [GO:0019905] 0 9.3511 AAAAAATAAAAASIR 0 0 0 0 0 0 9.94848 0 0 0 9.23752 0 0 0 0 0 0 8.88035 0 0 0 0 8.97327 9.32722 0 0 0 Q8WVP5 TP8L1_HUMAN Tumor necrosis factor alpha-induced protein 8-like protein 1 (TIPE1) (TNF alpha-induced protein 8-like protein 1) (TNFAIP8-like protein 1) (Oxidative stress-regulated gene-beta) (Oxy-beta) TNFAIP8L1 Homo sapiens (Human) negative regulation of TOR signaling [GO:0032007]; regulation of apoptotic process [GO:0042981] cytoplasm [GO:0005737] identical protein binding [GO:0042802] 0.9657 -2.3001 ATREFTR 10.5952 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WVQ1 CANT1_HUMAN Soluble calcium-activated nucleotidase 1 (SCAN-1) (EC 3.6.1.6) (Apyrase homolog) (Putative MAPK-activating protein PM09) (Putative NF-kappa-B-activating protein 107) CANT1 SHAPY Homo sapiens (Human) positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; proteoglycan biosynthetic process [GO:0030166] endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724] ADP phosphatase activity [GO:0043262]; calcium ion binding [GO:0005509]; GDP phosphatase activity [GO:0004382]; protein homodimerization activity [GO:0042803]; UDP phosphatase activity [GO:0045134] 0.97015 -3.25 AQEENTWFSYLKK 0 0 0 0 0 0 11.5357 11.65 11.4428 0 11.3135 11.5184 0 0 0 8.92333 9.35515 0 0 0 0 9.41282 0 0 0 0 9.49243 Q8WVR3 TPC14_HUMAN Trafficking protein particle complex subunit 14 (Microtubule-associated protein 11) TRAPPC14 C7orf43 MAP11 Homo sapiens (Human) cilium assembly [GO:0060271]; regulation of cell population proliferation [GO:0042127] centriolar satellite [GO:0034451]; intracellular membrane-bounded organelle [GO:0043231]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; plasma membrane [GO:0005886]; TRAPPII protein complex [GO:1990071] alpha-tubulin binding [GO:0043014] 0.9557 -1.5511 GGEQPPPGAK 0 0 0 0 0 0 0 0 0 0 0 0 0 12.0056 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WVT3 TPC12_HUMAN Trafficking protein particle complex subunit 12 (Tetratricopeptide repeat protein 15) (TPR repeat protein 15) (TTC-15) (Trafficking of membranes and mitosis) TRAPPC12 TRAMM TTC15 CGI-87 Homo sapiens (Human) COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; metaphase plate congression [GO:0051310]; positive regulation of protein localization to kinetochore [GO:1905342]; regulation of kinetochore assembly [GO:0090234]; vesicle tethering [GO:0099022] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; TRAPP complex [GO:0030008]; TRAPPIII protein complex [GO:1990072] 0.95309 -1.482 GVLRAVATQQR 0 0 0 8.38634 0 0 0 0 0 10.4109 9.37352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WVV9 HNRLL_HUMAN Heterogeneous nuclear ribonucleoprotein L-like (hnRNPLL) (Stromal RNA-regulating factor) HNRNPLL HNRPLL SRRF BLOCK24 Homo sapiens (Human) mRNA processing [GO:0006397]; positive regulation of RNA splicing [GO:0033120]; regulation of RNA splicing [GO:0043484] membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; synapse [GO:0045202] mRNA binding [GO:0003729]; RNA binding [GO:0003723] 0.68623 0.38887 ETYEEDR 0 10.3526 10.5149 0 0 10.3796 0 0 0 0 0 0 0 0 0 0 0 9.38319 0 0 9.68696 0 0 0 0 0 0 Q8WVX9 FACR1_HUMAN Fatty acyl-CoA reductase 1 (EC 1.2.1.84) (Male sterility domain-containing protein 2) FAR1 MLSTD2 UNQ2423/PRO4981 Homo sapiens (Human) ether lipid biosynthetic process [GO:0008611]; glycerophospholipid biosynthetic process [GO:0046474]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]; wax biosynthetic process [GO:0010025] peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777] alcohol-forming long-chain fatty acyl-CoA reductase activity [GO:0102965]; alcohol-forming very long-chain fatty acyl-CoA reductase activity [GO:0080019]; oxidoreductase activity [GO:0016491] 0.42013 0.67581 FLSYFRASSTMRY 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.85428 0 0 0 0 10.3837 0 0 Q8WVY7 UBCP1_HUMAN Ubiquitin-like domain-containing CTD phosphatase 1 (EC 3.1.3.16) (Nuclear proteasome inhibitor UBLCP1) UBLCP1 Homo sapiens (Human) protein dephosphorylation [GO:0006470] nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] metal ion binding [GO:0046872]; myosin phosphatase activity [GO:0017018]; protein serine/threonine phosphatase activity [GO:0004722] 0.55982 0.54704 LDDFLDLNHK 0 0 0 0 0 0 0 0 0 0 0 0 10.0264 9.16546 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WVZ7 RN133_HUMAN E3 ubiquitin-protein ligase RNF133 (EC 2.3.2.27) (RING finger protein 133) (RING-type E3 ubiquitin transferase RNF133) RNF133 Homo sapiens (Human) protein autoubiquitination [GO:0051865]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630] 0.91405 -0.78489 GTEIFHLIKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.98499 0 0 Q8WW14 CJ082_HUMAN Uncharacterized protein C10orf82 C10orf82 Homo sapiens (Human) cytoplasm [GO:0005737]; nucleus [GO:0005634] 0.88398 -0.26135 DFLEITERAK 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1454 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WW18 CQ050_HUMAN Uncharacterized protein C17orf50 C17orf50 Homo sapiens (Human) 0.96195 -2.5603 AGAAGNS 0 0 0 0 0 0 0 0 0 0 0 8.21815 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WW22 DNJA4_HUMAN DnaJ homolog subfamily A member 4 DNAJA4 Homo sapiens (Human) negative regulation of endothelial cell migration [GO:0010596]; negative regulation of inclusion body assembly [GO:0090084]; positive regulation of gene expression [GO:0010628]; protein refolding [GO:0042026]; response to heat [GO:0009408] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020] ATP binding [GO:0005524]; Hsp70 protein binding [GO:0030544]; metal ion binding [GO:0046872]; protein-folding chaperone binding [GO:0051087]; unfolded protein binding [GO:0051082] 0.43288 0.65304 GHDLIMK 0 0 0 0 0 0 0 0 0 0 0 12.3111 0 0 0 10.3128 0 9.59483 0 0 0 0 0 0 0 0 0 Q8WW24 TEKT4_HUMAN Tektin-4 TEKT4 Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement involved in cell motility [GO:0060294] axonemal microtubule [GO:0005879]; microtubule cytoskeleton [GO:0015630]; nucleus [GO:0005634]; sperm flagellum [GO:0036126] 0.95814 -1.672 NLEDIHMSLEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6678 Q8WW33 GTSF1_HUMAN Gametocyte-specific factor 1 (Protein FAM112B) GTSF1 FAM112B Homo sapiens (Human) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737] metal ion binding [GO:0046872]; tRNA binding [GO:0000049] 0.88429 -0.14272 KNHPDVASKLATCPFNAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.36794 0 0 0 0 0 0 0 0 0 0 Q8WW38 FOG2_HUMAN Zinc finger protein ZFPM2 (Friend of GATA protein 2) (FOG-2) (Friend of GATA 2) (hFOG-2) (Zinc finger protein 89B) (Zinc finger protein multitype 2) ZFPM2 FOG2 ZNF89B Homo sapiens (Human) cell differentiation [GO:0030154]; embryonic organ development [GO:0048568]; fat cell differentiation [GO:0045444]; gonadal mesoderm development [GO:0007506]; heart development [GO:0007507]; in utero embryonic development [GO:0001701]; lung development [GO:0030324]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of female gonad development [GO:2000195]; negative regulation of transcription by RNA polymerase II [GO:0000122]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of male gonad development [GO:2000020]; positive regulation of transcription by RNA polymerase II [GO:0045944]; right ventricular cardiac muscle tissue morphogenesis [GO:0003221]; vasculogenesis [GO:0001570]; ventricular septum morphogenesis [GO:0060412] chromatin [GO:0000785]; cytoplasm [GO:0005737]; male germ cell nucleus [GO:0001673]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; zinc ion binding [GO:0008270] 0.91535 -0.79184 KMYEMCLPEQEQRPPLVQQR 0 0 0 0 9.28866 9.15785 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.97375 0 0 Q8WW52 F151A_HUMAN Protein FAM151A FAM151A C1orf179 UNQ3034/PRO9836 Homo sapiens (Human) extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020] 0.3084 0.79658 TYTQAMVEK 0 0 16.3617 0 0 0 0 15.9361 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WW62 TMED6_HUMAN Transmembrane emp24 domain-containing protein 6 (p24 family protein gamma-5) (p24gamma5) TMED6 UNQ9146/PRO34237 Homo sapiens (Human) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886] COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794] 0.86963 0.046895 VQNNIFHMWR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.95217 0 0 Q8WWA0 ITLN1_HUMAN Intelectin-1 (ITLN-1) (Endothelial lectin HL-1) (Galactofuranose-binding lectin) (Intestinal lactoferrin receptor) (Omentin) ITLN1 INTL ITLN LFR UNQ640/PRO1270 Homo sapiens (Human) positive regulation of glucose import [GO:0046326]; positive regulation of protein phosphorylation [GO:0001934]; protein homotrimerization [GO:0070207]; response to nematode [GO:0009624] brush border membrane [GO:0031526]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane raft [GO:0045121]; receptor complex [GO:0043235] calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; oligosaccharide binding [GO:0070492] 0.95443 -1.5316 YPVKYGEGK 0 0 0 0 0 11.7694 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WWB5 PIHD2_HUMAN PIH1 domain-containing protein 2 PIH1D2 Homo sapiens (Human) box C/D snoRNP assembly [GO:0000492]; protein stabilization [GO:0050821]; rRNA processing [GO:0006364] cytoplasm [GO:0005737]; protein folding chaperone complex [GO:0101031]; R2TP complex [GO:0097255]; ribonucleoprotein complex [GO:1990904] small GTPase binding [GO:0031267] 0.96987 -4.1612 CIEEKFQFTLSHSYHITK 0 0 0 0 10.9591 0 0 0 0 0 0 10.793 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WWF3 SSMM1_HUMAN Serine-rich single-pass membrane protein 1 SSMEM1 C7orf45 Homo sapiens (Human) membrane [GO:0016020] 0.70161 0.37274 HCLHCKALRTNEWLAHHSR 0 0 0 0 0 0 0 0 0 0 8.93402 0 0 0 0 0 0 0 0 0 0 0 0 9.55789 0 0 0 Q8WWF8 CAPSL_HUMAN Calcyphosin-like protein CAPSL Homo sapiens (Human) cytoplasm [GO:0005737] calcium ion binding [GO:0005509] 0.88334 -0.059335 VFRIMDDDNNRTLDFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8281 0 0 0 0 0 0 0 0 0 0 0 Q8WWH4 ASZ1_HUMAN "Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Ankyrin-like protein 1) (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein)" ASZ1 ALP1 ANKL1 C7orf7 GASZ Homo sapiens (Human) cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; male meiotic nuclear division [GO:0007140]; piRNA processing [GO:0034587]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; pi-body [GO:0071546] 0.61462 0.42471 VLLDRGANASFEKDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.83539 0 0 0 0 0 0 0 0 0 0 Q8WWH5 TRUB1_HUMAN Pseudouridylate synthase TRUB1 (EC 5.4.99.-) (TruB pseudouridine synthase homolog 1) (tRNA pseudouridine 55 synthase TRUB1) (Psi55 synthase TRUB1) (EC 5.4.99.25) TRUB1 PUS4 Homo sapiens (Human) mRNA processing [GO:0006397]; mRNA pseudouridine synthesis [GO:1990481]; positive regulation of pre-miRNA processing [GO:2000633]; tRNA modification [GO:0006400] cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634] pre-miRNA binding [GO:0070883]; pseudouridine synthase activity [GO:0009982] 0.39908 0.7057 REDDVIKTC 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.1486 Q8WWI1 LMO7_HUMAN LIM domain only protein 7 (LMO-7) (F-box only protein 20) (LOMP) LMO7 FBX20 FBXO20 KIAA0858 Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944]; protein ubiquitination [GO:0016567]; regulation of cell adhesion [GO:0030155]; regulation of signaling [GO:0023051] apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151] metal ion binding [GO:0046872]; ubiquitin-protein transferase activity [GO:0004842] 0.96833 -9.1414 EEREEIEKQALEK 0 0 0 0 0 0 11.3847 0 0 11.3455 0 0 0 0 0 0 9.33604 0 9.49067 0 9.80603 0 0 0 0 0 0 Q8WWK9 CKAP2_HUMAN Cytoskeleton-associated protein 2 (CTCL tumor antigen se20-10) (Tumor- and microtubule-associated protein) CKAP2 LB1 TMAP Homo sapiens (Human) apoptotic process [GO:0006915]; mitotic cytokinesis [GO:0000281]; negative regulation of microtubule depolymerization [GO:0007026]; positive regulation of transcription by RNA polymerase II [GO:0045944] centrosome [GO:0005813]; cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; mitotic spindle [GO:0072686]; spindle pole [GO:0000922] 0.96867 -5.8077 EDILVTLNDLIKNIPDAK 0 0 0 0 0 11.636 0 9.00445 0 9.46164 0 0 0 0 0 0 10.2352 9.90872 0 0 0 0 0 0 0 11.0188 0 Q8WWL2 SPIR2_HUMAN Protein spire homolog 2 (Spir-2) SPIRE2 KIAA1832 SPIR2 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament network formation [GO:0051639]; actin filament polymerization [GO:0030041]; actin nucleation [GO:0045010]; cleavage furrow formation [GO:0036089]; establishment of meiotic spindle localization [GO:0051295]; formin-nucleated actin cable assembly [GO:0070649]; Golgi vesicle transport [GO:0048193]; intracellular transport [GO:0046907]; polar body extrusion after meiotic divisions [GO:0040038]; positive regulation of double-strand break repair [GO:2000781]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] cell cortex [GO:0005938]; cleavage furrow [GO:0032154]; cytoplasmic vesicle membrane [GO:0030659]; cytoskeleton [GO:0005856]; cytosol [GO:0005829] actin binding [GO:0003779] 0.95429 -1.5183 ELSPQLER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.25824 0 0 0 0 0 0 Q8WWL7 CCNB3_HUMAN G2/mitotic-specific cyclin-B3 CCNB3 CYCB3 Homo sapiens (Human) cell division [GO:0051301]; meiotic cell cycle [GO:0051321]; mitotic cell cycle phase transition [GO:0044772]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079] centrosome [GO:0005813]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleus [GO:0005634] cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538] 0.92305 -1.0615 EIFSYMKER 10.1195 0 0 9.49825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1688 0 Q8WWM1 XAGE5_HUMAN X antigen family member 5 (XAGE-5) (Cancer/testis antigen 12.5) (CT12.5) (G antigen family D member 5) XAGE5 GAGED5 Homo sapiens (Human) 0.67638 0.39361 TGDECGDSPDVQGKILPK 0 14.7414 0 12.5268 0 11.7708 13.7154 0 15.0304 13.7475 14.0689 13.8924 13.0382 13.0919 13.1025 0 14.3359 13.2098 11.208 0 10.2011 0 0 9.89294 0 0 0 Q8WWM7 ATX2L_HUMAN Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein) ATXN2L A2D A2LG A2LP A2RP Homo sapiens (Human) mRNA metabolic process [GO:0016071]; stress granule assembly [GO:0034063] cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607] cadherin binding [GO:0045296]; mRNA binding [GO:0003729]; RNA binding [GO:0003723] 0.19375 0.93081 GINGGPSR 0 0 0 0 0 0 0 0 0 10.3194 0 10.1551 0 0 0 0 0 0 0 10.7221 0 0 0 0 9.28559 0 8.69902 Q8WWN8 ARAP3_HUMAN "Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 (Centaurin-delta-3) (Cnt-d3)" ARAP3 CENTD3 Homo sapiens (Human) cytoskeleton organization [GO:0007010]; positive regulation of GTPase activity [GO:0043547]; signal transduction [GO:0007165]; vesicle-mediated transport [GO:0016192] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886]; ruffle [GO:0001726] "GTPase activator activity [GO:0005096]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]" 0.96213 -2.4605 DNKFQVITGQRVFVFR 0 0 0 0 0 0 0 0 0 9.1172 0 0 9.541 0 0 0 0 9.3828 9.26807 0 10.4659 0 0 0 0 0 0 Q8WWQ0 PHIP_HUMAN PH-interacting protein (PHIP) (DDB1- and CUL4-associated factor 14) (IRS-1 PH domain-binding protein) (WD repeat-containing protein 11) PHIP DCAF14 WDR11 Homo sapiens (Human) cytoskeleton organization [GO:0007010]; insulin receptor signaling pathway [GO:0008286]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell morphogenesis [GO:0022604]; regulation of cell shape [GO:0008360]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] insulin receptor binding [GO:0005158]; lysine-acetylated histone binding [GO:0070577] 0.96912 -3.8952 DIIDTPMDFATVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.8399 0 0 10.4613 8.92407 0 0 10.2322 0 8.93984 8.90758 10.3599 Q8WWQ8 STAB2_HUMAN "Stabilin-2 (FAS1 EGF-like and X-link domain-containing adhesion molecule 2) (Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2) (FEEL-2) (Hyaluronan receptor for endocytosis) [Cleaved into: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)]" STAB2 FEEL2 FELL FEX2 HARE Homo sapiens (Human) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; endocytosis [GO:0006897]; hyaluronan catabolic process [GO:0030214]; receptor-mediated endocytosis [GO:0006898] cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; external side of plasma membrane [GO:0009897]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; hyaluronic acid binding [GO:0005540]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor activity [GO:0005041]; protein-disulfide reductase activity [GO:0015035]; scavenger receptor activity [GO:0005044] 0.96846 -3.3496 AFLEHLTDLSIR 10.991 14.1786 14.2829 10.7248 10.6662 10.668 13.9661 14.2123 14.212 12.3641 10.6465 14.4757 9.33865 0 9.45588 0 0 9.58556 0 0 0 0 0 0 10.5096 9.50665 11.0672 Q8WWR8 NEUR4_HUMAN Sialidase-4 (EC 3.2.1.18) (N-acetyl-alpha-neuraminidase 4) NEU4 LP5125 Homo sapiens (Human) ganglioside catabolic process [GO:0006689]; glycoprotein catabolic process [GO:0006516]; negative regulation of neuron projection development [GO:0010977]; oligosaccharide catabolic process [GO:0009313] cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; organelle inner membrane [GO:0019866]; plasma membrane [GO:0005886] exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; exo-alpha-sialidase activity [GO:0004308] 0.94567 -1.3425 LLVPAYTYRVDRR 0 0 0 0 0 0 0 0 0 0 0 0 12.9421 0 0 0 0 13.4025 0 0 0 0 0 0 0 0 0 Q8WWV3 RT4I1_HUMAN "Reticulon-4-interacting protein 1, mitochondrial (NOGO-interacting mitochondrial protein)" RTN4IP1 NIMP Homo sapiens (Human) nervous system development [GO:0007399]; regulation of dendrite development [GO:0050773] mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739] oxidoreductase activity [GO:0016491]; zinc ion binding [GO:0008270] 0.74546 0.31801 ISTTSPR 0 0 0 0 0 0 0 11.4598 0 0 0 10.783 0 0 0 0 0 9.38547 0 0 0 0 0 0 0 0 8.77903 Q8WWV6 FCAMR_HUMAN High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor (Fc alpha/mu receptor) (CD antigen CD351) FCAMR FKSG87 Homo sapiens (Human) adaptive immune response [GO:0002250] plasma membrane [GO:0005886] transmembrane signaling receptor activity [GO:0004888] 0.90801 -0.73478 TTASAEGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.20149 0 0 0 0 0 0 0 0 Q8WWW0 RASF5_HUMAN Ras association domain-containing protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL) RASSF5 NORE1 RAPL Homo sapiens (Human) apoptotic process [GO:0006915]; lymphocyte proliferation [GO:0046651]; negative regulation of lymphocyte proliferation [GO:0050672]; positive regulation of protein ubiquitination [GO:0031398]; regulation of protein localization to nucleus [GO:1900180]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleus [GO:0005634] identical protein binding [GO:0042802]; metal ion binding [GO:0046872] 0.90677 -0.74146 LSEDGTYTGFIKVHLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.85747 0 0 0 0 0 0 0 0 Q8WWW8 GAB3_HUMAN GRB2-associated-binding protein 3 (GRB2-associated binder 3) (Growth factor receptor bound protein 2-associated protein 3) GAB3 Homo sapiens (Human) macrophage differentiation [GO:0030225]; signal transduction [GO:0007165] cytoplasm [GO:0005737] signaling adaptor activity [GO:0035591] 0.92227 -1.1348 NQGSLPCGAK 0 0 0 0 0 0 0 0 0 9.87477 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WWY3 PRP31_HUMAN U4/U6 small nuclear ribonucleoprotein Prp31 (Pre-mRNA-processing factor 31) (Serologically defined breast cancer antigen NY-BR-99) (U4/U6 snRNP 61 kDa protein) (Protein 61K) (hPrp31) PRPF31 PRP31 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; ribonucleoprotein complex localization [GO:0071166]; spliceosomal tri-snRNP complex assembly [GO:0000244]" Cajal body [GO:0015030]; MLL1 complex [GO:0071339]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; precatalytic spliceosome [GO:0071011]; spliceosomal tri-snRNP complex [GO:0097526]; U2-type precatalytic spliceosome [GO:0071005]; U2-type spliceosomal complex [GO:0005684]; U4 snRNP [GO:0005687]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U4atac snRNP [GO:0005690] identical protein binding [GO:0042802]; ribonucleoprotein complex binding [GO:0043021]; RNA binding [GO:0003723]; snRNP binding [GO:0070990]; U4 snRNA binding [GO:0030621]; U4atac snRNA binding [GO:0030622] 0.96784 -2.8897 LGLTEIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3485 0 0 0 0 0 0 Q8WWY8 LIPH_HUMAN Lipase member H (LIPH) (EC 3.1.1.-) (LPD lipase-related protein) (Membrane-associated phosphatidic acid-selective phospholipase A1-alpha) (mPA-PLA1 alpha) (Phospholipase A1 member B) LIPH LPDLR MPAPLA1 PLA1B Homo sapiens (Human) lipid catabolic process [GO:0016042]; phosphatidic acid biosynthetic process [GO:0006654] extracellular space [GO:0005615]; plasma membrane [GO:0005886] carboxylic ester hydrolase activity [GO:0052689]; heparin binding [GO:0008201]; phospholipase activity [GO:0004620] 0.91659 -0.77462 LRSLAHPERPQLCR 0 0 10.828 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WWZ3 EDAD_HUMAN Ectodysplasin-A receptor-associated adapter protein (EDAR-associated death domain protein) (Protein crinkled homolog) EDARADD Homo sapiens (Human) cell differentiation [GO:0030154]; signal transduction [GO:0007165] cytosol [GO:0005829] 0.6484 0.396 LDPCHPTVK 0 0 0 0 0 0 0 8.58778 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.92973 0 0 0 Q8WWZ4 ABCAA_HUMAN ATP-binding cassette sub-family A member 10 (EC 7.6.2.-) ABCA10 Homo sapiens (Human) lipid transport [GO:0006869] intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020] ABC-type transporter activity [GO:0140359]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]; lipid transporter activity [GO:0005319] 0.96942 -4.6577 FLGYCPQENSLWPK 0 0 0 0 0 0 0 0 9.65173 0 0 11.3007 12.0149 0 12.5568 9.79824 12.4024 0 0 0 0 0 0 0 0 0 0 Q8WWZ7 ABCA5_HUMAN Cholesterol transporter ABCA5 (EC 7.6.2.-) (ATP-binding cassette sub-family A member 5) ABCA5 KIAA1888 Homo sapiens (Human) cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; high-density lipoprotein particle remodeling [GO:0034375]; lipid transport [GO:0006869]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; positive regulation of reverse cholesterol transport [GO:1903064]; regulation of cholesterol efflux [GO:0010874]; reverse cholesterol transport [GO:0043691] Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; plasma membrane [GO:0005886] ABC-type transporter activity [GO:0140359]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]; lipid transporter activity [GO:0005319] 0.915 -0.77079 ISGIQKTYRK 0 0 10.3392 10.2194 10.2897 0 11.9559 11.948 11.9026 0 0 0 0 12.3054 12.487 0 0 0 0 0 0 9.97312 0 10.22 0 0 0 Q8WWZ8 OIT3_HUMAN Oncoprotein-induced transcript 3 protein (Liver-specific zona pellucida domain-containing protein) OIT3 LZP UNQ826/PRO1753 Homo sapiens (Human) renal system process [GO:0003014] nuclear envelope [GO:0005635] calcium ion binding [GO:0005509] 0.951 -1.4004 VLVCGVLDERSRCAQGCHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.685 0 0 Q8WX92 NELFB_HUMAN Negative elongation factor B (NELF-B) (Cofactor of BRCA1) NELFB COBRA1 KIAA1182 Homo sapiens (Human) cell population proliferation [GO:0008283]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; stem cell differentiation [GO:0048863] cytoplasm [GO:0005737]; NELF complex [GO:0032021]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] RNA binding [GO:0003723] 0.94794 -1.3601 ELYSQLGEK 0 0 0 8.52697 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.98214 Q8WX94 NALP7_HUMAN "NACHT, LRR and PYD domains-containing protein 7 (Nucleotide-binding oligomerization domain protein 12) (PYRIN-containing APAF1-like protein 3)" NLRP7 NALP7 NOD12 PYPAF3 Homo sapiens (Human) cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of protein processing [GO:0010955]; regulation of inflammatory response [GO:0050727] cytoplasm [GO:0005737] aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP binding [GO:0005524]; caspase binding [GO:0089720]; identical protein binding [GO:0042802]; interleukin-1 binding [GO:0019966] 0.96258 -2.5024 DLQLLAQQPIYVR 9.43256 0 0 0 0 0 0 8.56723 0 0 0 0 0 0 0 0 0 0 0 10.6993 0 0 0 0 0 0 0 Q8WXA3 RUFY2_HUMAN RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related) RUFY2 KIAA1537 RABIP4R Homo sapiens (Human) regulation of endocytosis [GO:0030100] cytoplasm [GO:0005737]; endosome [GO:0005768]; nucleus [GO:0005634] metal ion binding [GO:0046872]; SH3 domain binding [GO:0017124] 0.96742 -3.7979 ATKDPTAVER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.202 0 0 0 0 0 0 0 0 9.8997 0 9.45119 Q8WXB4 ZN606_HUMAN Zinc finger protein 606 (Zinc finger protein 328) ZNF606 KIAA1852 ZNF328 Homo sapiens (Human) nucleoplasm [GO:0005654] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.89819 -0.63263 AFSGHSALLQHQRNHSEEK 0 0 0 0 0 0 9.77798 0 0 0 0 0 0 0 9.57784 0 0 0 0 9.35949 0 0 0 0 0 0 0 Q8WXC3 PYDC1_HUMAN Pyrin domain-containing protein 1 (PAAD-only protein 1) (Pyrin-only protein 1) (cellular POP1) (cPOP1) PYDC1 ASC2 ASCI POP1 PYC1 Homo sapiens (Human) innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; positive regulation of interleukin-1 beta production [GO:0032731]; tumor necrosis factor-mediated signaling pathway [GO:0033209] cytosol [GO:0005829]; IkappaB kinase complex [GO:0008385]; nucleus [GO:0005634] 0.83452 0.18746 MLEEAAR 0 10.0463 0 0 0 0 0 0 0 9.74908 10.0729 9.86646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WXD0 RXFP2_HUMAN Relaxin receptor 2 (G-protein coupled receptor 106) (G-protein coupled receptor affecting testicular descent) (Leucine-rich repeat-containing G-protein coupled receptor 8) (Relaxin family peptide receptor 2) RXFP2 GPR106 GREAT LGR8 Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; hormone-mediated signaling pathway [GO:0009755]; male gonad development [GO:0008584] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; protein-hormone receptor activity [GO:0016500] 0.83346 0.1995 NQIGFVPEK 0 0 0 0 0 0 9.27018 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WXD2 SCG3_HUMAN Secretogranin-3 (Secretogranin III) (SgIII) SCG3 UNQ2502/PRO5990 Homo sapiens (Human) protein localization to secretory granule [GO:0033366] endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; secretory granule lumen [GO:0034774]; secretory granule membrane [GO:0030667]; transport vesicle membrane [GO:0030658] RNA binding [GO:0003723] 0.94699 -1.3531 MRDFINKQADAYVEK 0 0 0 9.40784 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WXD9 CSKI1_HUMAN Caskin-1 (CASK-interacting protein 1) CASKIN1 KIAA1306 Homo sapiens (Human) signal transduction [GO:0007165] cytoplasm [GO:0005737] identical protein binding [GO:0042802] 0.9327 -1.2583 AEDVGTAQR 0 0 0 0 0 0 0 0 0 11.022 0 0 0 0 10.149 0 0 0 0 0 0 0 0 0 0 0 0 Q8WXE1 ATRIP_HUMAN ATR-interacting protein (ATM and Rad3-related-interacting protein) ATRIP AGS1 Homo sapiens (Human) DNA damage checkpoint signaling [GO:0000077]; DNA repair [GO:0006281]; nucleobase-containing compound metabolic process [GO:0006139]; regulation of double-strand break repair [GO:2000779] ATR-ATRIP complex [GO:0070310]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] K63-linked polyubiquitin modification-dependent protein binding [GO:0070530] 0.91675 -0.76775 AGGPPRTDQQRR 0 0 0 0 0 0 0 0 8.736 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WXE9 STON2_HUMAN Stonin-2 (Stoned B) STON2 STN2 STNB Homo sapiens (Human) clathrin-dependent endocytosis [GO:0072583]; regulation of endocytosis [GO:0030100]; synaptic vesicle endocytosis [GO:0048488] AP-2 adaptor complex [GO:0030122]; cytosol [GO:0005829]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; synaptic vesicle [GO:0008021] clathrin adaptor activity [GO:0035615] 0.923 -1.0816 YPVPSEWVK 0 0 0 0 0 0 0 0 0 0 0 10.754 0 0 0 0 0 0 0 0 0 10.3791 0 0 0 0 0 Q8WXF0 SRS12_HUMAN "Serine/arginine-rich splicing factor 12 (35 kDa SR repressor protein) (SRrp35) (Splicing factor, arginine/serine-rich 13B) (Splicing factor, arginine/serine-rich 19)" SRSF12 SFRS13B SFRS19 SRRP35 Homo sapiens (Human) "mRNA 5'-splice site recognition [GO:0000395]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; spliceosomal tri-snRNP complex assembly [GO:0000244]" nuclear speck [GO:0016607]; nucleoplasm [GO:0005654] RNA binding [GO:0003723]; RS domain binding [GO:0050733]; unfolded protein binding [GO:0051082] 0.96147 -2.5685 QTSSGTK 0 0 0 9.41532 0 0 0 0 0 9.70803 0 0 9.35443 0 0 0 0 0 0 0 10.218 0 0 0 0 0 0 Q8WXF3 REL3_HUMAN Relaxin-3 (Insulin-like peptide INSL7) (Insulin-like peptide 7) (Prorelaxin H3) [Cleaved into: Relaxin-3 B chain; Relaxin-3 A chain] RLN3 INSL7 RXN3 ZINS4 UNQ6188/PRO20213 Homo sapiens (Human) extracellular region [GO:0005576] G protein-coupled receptor binding [GO:0001664]; hormone activity [GO:0005179] 0.80834 0.22916 AVIFTCGGSR 0 0 10.3097 0 0 0 0 0 0 0 0 0 0 0 0 10.4214 0 0 0 0 0 0 0 0 0 0 0 Q8WXF7 ATLA1_HUMAN Atlastin-1 (EC 3.6.5.-) (Brain-specific GTP-binding protein) (GTP-binding protein 3) (GBP-3) (hGBP3) (Guanine nucleotide-binding protein 3) (Spastic paraplegia 3 protein A) ATL1 GBP3 SPG3A Homo sapiens (Human) axonogenesis [GO:0007409]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum tubular network membrane organization [GO:1990809]; protein homooligomerization [GO:0051260] axon [GO:0030424]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum tubular network [GO:0071782]; endoplasmic reticulum tubular network membrane [GO:0098826]; Golgi apparatus [GO:0005794]; Golgi cis cisterna [GO:0000137]; Golgi membrane [GO:0000139]; membrane [GO:0016020] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802] 0.92973 -1.2453 EIDDEFIKNLK 0 0 0 0 0 0 0 10.8797 0 0 0 0 0 9.32296 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WXF8 DEDD2_HUMAN DNA-binding death effector domain-containing protein 2 (DED-containing protein FLAME-3) (FADD-like anti-apoptotic molecule 3) DEDD2 FLAME3 PSEC0004 Homo sapiens (Human) apoptotic nuclear changes [GO:0030262]; cellular homeostasis [GO:0019725]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intracellular signal transduction [GO:0035556]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075] nucleolus [GO:0005730]; nucleoplasm [GO:0005654] DNA binding [GO:0003677]; signaling receptor complex adaptor activity [GO:0030159] 0.93872 -1.3202 LLVSVDEADYEAGRRR 0 0 0 0 0 0 0 11.4355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WXG6 MADD_HUMAN MAP kinase-activating death domain protein (Differentially expressed in normal and neoplastic cells) (Insulinoma glucagonoma clone 20) (Rab3 GDP/GTP exchange factor) (RabGEF) (Rab3 GDP/GTP exchange protein) (Rab3GEP) MADD DENN IG20 KIAA0358 Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; execution phase of apoptosis [GO:0097194]; positive regulation of MAPK cascade [GO:0043410]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of extrinsic apoptotic signaling pathway [GO:2001236]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of Rab protein signal transduction [GO:0032483] axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886] death receptor binding [GO:0005123]; guanyl-nucleotide exchange factor activity [GO:0005085]; protein kinase activator activity [GO:0030295] 0.96985 -4.6842 AHSLKPSIKEK 0 0 0 0 0 10.6995 0 0 0 0 10.5918 0 12.4421 0 9.21471 10.8794 12.1902 10.3692 10.5252 0 0 0 0 0 0 0 0 Q8WXG9 AGRV1_HUMAN Adhesion G-protein coupled receptor V1 (ADGRV1) (EC 3.4.-.-) (G-protein coupled receptor 98) (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Usher syndrome type-2C protein) (Very large G-protein coupled receptor 1) [Cleaved into: ADGRV1 subunit alpha; ADGRV1 subunit beta] ADGRV1 GPR98 KIAA0686 KIAA1943 MASS1 VLGR1 Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to calcium ion [GO:0071277]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; establishment of protein localization [GO:0045184]; G protein-coupled receptor signaling pathway [GO:0007186]; inner ear development [GO:0048839]; inner ear receptor cell differentiation [GO:0060113]; inner ear receptor cell stereocilium organization [GO:0060122]; maintenance of animal organ identity [GO:0048496]; negative regulation of adenylate cyclase activity [GO:0007194]; nervous system development [GO:0007399]; nervous system process [GO:0050877]; photoreceptor cell maintenance [GO:0045494]; positive regulation of bone mineralization [GO:0030501]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase C signaling [GO:0090037]; regulation of protein stability [GO:0031647]; self proteolysis [GO:0097264]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; periciliary membrane compartment [GO:1990075]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; stereocilia ankle link [GO:0002141]; stereocilia ankle link complex [GO:0002142]; stereocilium [GO:0032420]; stereocilium membrane [GO:0060171]; synapse [GO:0045202]; USH2 complex [GO:1990696] adenylate cyclase inhibitor activity [GO:0010855]; calcium ion binding [GO:0005509]; G protein-coupled receptor activity [GO:0004930]; G-protein alpha-subunit binding [GO:0001965]; hydrolase activity [GO:0016787] 0.88331 -0.11043 DSGTGLMMSVNFSTQELR 0 10.0992 10.1126 9.93652 9.97284 9.99563 11.7847 11.7548 0 0 0 11.9729 0 11.7683 11.7439 0 0 0 10.3463 0 0 0 0 0 0 10.0538 10.6448 Q8WXH0 SYNE2_HUMAN Nesprin-2 (KASH domain-containing protein 2) (KASH2) (Nuclear envelope spectrin repeat protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE) (Synaptic nuclear envelope protein 2) (Syne-2) SYNE2 KIAA1011 NUA Homo sapiens (Human) centrosome localization [GO:0051642]; nuclear migration [GO:0007097]; nuclear migration along microfilament [GO:0031022]; nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration [GO:0021817]; positive regulation of cell migration [GO:0030335]; regulation of cilium assembly [GO:1902017] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; intermediate filament cytoskeleton [GO:0045111]; lamellipodium membrane [GO:0031258]; meiotic nuclear membrane microtubule tethering complex [GO:0034993]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear lumen [GO:0031981]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; Z disc [GO:0030018] actin binding [GO:0003779]; cytoskeleton-nuclear membrane anchor activity [GO:0140444] 0.96811 -9.2823 ADAYTVELENAESR 16.4433 0 0 0 10.5858 0 0 0 10.6782 10.9205 9.91127 10.8084 0 11.2802 9.58517 0 11.016 0 9.3382 0 0 10.2861 10.0715 0 0 0 12.0173 Q8WXH2 JPH3_HUMAN Junctophilin-3 (JP-3) (Junctophilin type 3) (Trinucleotide repeat-containing gene 22 protein) JPH3 JP3 TNRC22 Homo sapiens (Human) calcium ion transport into cytosol [GO:0060402]; exploration behavior [GO:0035640]; learning [GO:0007612]; locomotion [GO:0040011]; memory [GO:0007613]; neuromuscular process controlling balance [GO:0050885]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of synaptic plasticity [GO:0048167] endoplasmic reticulum membrane [GO:0005789]; junctional membrane complex [GO:0030314]; junctional sarcoplasmic reticulum membrane [GO:0014701]; membrane [GO:0016020]; plasma membrane [GO:0005886] 0.95399 -1.5224 LLELQEEKLSNYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.64245 0 0 0 0 9.52164 0 Q8WXI2 CNKR2_HUMAN Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR 2) (CNK homolog protein 2) (CNK2) CNKSR2 CNK2 KIAA0902 KSR2 Homo sapiens (Human) intracellular signal transduction [GO:0035556]; postsynapse organization [GO:0099173]; regulation of signal transduction [GO:0009966] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of postsynaptic density membrane [GO:0099147]; glutamatergic synapse [GO:0098978]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886] identical protein binding [GO:0042802]; protein kinase binding [GO:0019901] 0.96438 -2.4325 DLGRGDCEGWLWKK 0 0 0 0 0 0 0 0 10.6782 0 0 0 0 0 0 0 0 0 0 0 0 9.72806 0 0 0 0 0 Q8WXI4 ACO11_HUMAN Acyl-coenzyme A thioesterase 11 (Acyl-CoA thioesterase 11) (EC 3.1.2.-) (Acyl-CoA thioester hydrolase 11) (Adipose-associated thioesterase) (Brown fat-inducible thioesterase) (BFIT) (Palmitoyl-coenzyme A thioesterase) (EC 3.1.2.2) ACOT11 BFIT KIAA0707 THEA Homo sapiens (Human) fatty acid metabolic process [GO:0006631]; intracellular signal transduction [GO:0035556]; negative regulation of cold-induced thermogenesis [GO:0120163]; response to cold [GO:0009409]; response to temperature stimulus [GO:0009266] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759] acyl-CoA hydrolase activity [GO:0047617]; carboxylic ester hydrolase activity [GO:0052689]; lipid binding [GO:0008289]; long-chain acyl-CoA hydrolase activity [GO:0052816]; myristoyl-CoA hydrolase activity [GO:0102991]; palmitoyl-CoA hydrolase activity [GO:0016290] 0.8449 0.15313 AIEMFHFR 0 0 0 0 0 0 0 8.72959 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WXI7 MUC16_HUMAN Mucin-16 (MUC-16) (Ovarian cancer-related tumor marker CA125) (CA-125) (Ovarian carcinoma antigen CA125) MUC16 CA125 Homo sapiens (Human) cell adhesion [GO:0007155] extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; vesicle [GO:0031982] 0.95219 -1.4499 EPSISPEIR 0 0 0 0 0 0 0 0 0 10.2131 15.3317 0 11.3809 0 0 0 13.2292 13.2781 0 0 0 0 0 0 0 12.6159 11.0878 Q8WXJ9 ASB17_HUMAN Ankyrin repeat and SOCS box protein 17 (ASB-17) ASB17 Homo sapiens (Human) intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567] cytosol [GO:0005829] 0.92423 -1.0644 DPCELLHLCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.79711 0 0 Q8WXK1 ASB15_HUMAN Ankyrin repeat and SOCS box protein 15 (ASB-15) ASB15 Homo sapiens (Human) "Golgi to lysosome transport [GO:0090160]; intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567]; retrograde transport, endosome to Golgi [GO:0042147]" cytosol [GO:0005829]; endosome membrane [GO:0010008] small GTPase binding [GO:0031267] 0.92437 -1.0086 AAYEGHYLALK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.53493 0 0 0 0 0 0 0 Q8WXR4 MYO3B_HUMAN Myosin-IIIb (EC 2.7.11.1) MYO3B Homo sapiens (Human) cochlea morphogenesis [GO:0090103]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of filopodium assembly [GO:0051491]; regulation of actin filament length [GO:0030832]; response to stimulus [GO:0050896]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] cytoplasm [GO:0005737]; filopodium tip [GO:0032433]; myosin complex [GO:0016459]; photoreceptor inner segment [GO:0001917]; stereocilium tip [GO:0032426] actin binding [GO:0003779]; ATP binding [GO:0005524]; microfilament motor activity [GO:0000146]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96182 -2.0456 FPQATDQTLVDKFEDNLRCK 0 0 0 0 0 9.20809 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WXS5 CCG8_HUMAN Voltage-dependent calcium channel gamma-8 subunit (Neuronal voltage-gated calcium channel gamma-8 subunit) (Transmembrane AMPAR regulatory protein gamma-8) (TARP gamma-8) CACNG8 CACNG6 Homo sapiens (Human) "calcium ion transport [GO:0006816]; neurotransmitter receptor internalization [GO:0099590]; neurotransmitter receptor transport, postsynaptic endosome to lysosome [GO:0098943]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; regulation of AMPA receptor activity [GO:2000311]; regulation of monoatomic ion transmembrane transport [GO:0034765]; transmission of nerve impulse [GO:0019226]" AMPA glutamate receptor complex [GO:0032281]; endocytic vesicle membrane [GO:0030666]; L-type voltage-gated calcium channel complex [GO:1990454]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; voltage-gated calcium channel complex [GO:0005891] calcium channel regulator activity [GO:0005246]; channel regulator activity [GO:0016247]; voltage-gated calcium channel activity [GO:0005245] 0.95573 -1.5888 LPSYRFR 0 10.1882 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WXS8 ATS14_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 14 (ADAM-TS 14) (ADAM-TS14) (ADAMTS-14) (EC 3.4.24.-) ADAMTS14 Homo sapiens (Human) collagen catabolic process [GO:0030574]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; proteolysis [GO:0006508] extracellular matrix [GO:0031012]; extracellular region [GO:0005576] metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222] 0.95951 -1.8868 LIMVGYRQSLSLIER 0 0 0 0 0 0 0 0 0 0 9.08388 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WXU2 DAAF4_HUMAN Dynein axonemal assembly factor 4 (Dyslexia susceptibility 1 candidate gene 1 protein) DNAAF4 DYX1C1 EKN1 Homo sapiens (Human) cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; heart development [GO:0007507]; inner dynein arm assembly [GO:0036159]; learning or memory [GO:0007611]; neuron migration [GO:0001764]; outer dynein arm assembly [GO:0036158]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of proteasomal protein catabolic process [GO:0061136] centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dynein axonemal particle [GO:0120293]; extracellular region [GO:0005576]; neuron projection [GO:0043005]; non-motile cilium [GO:0097730]; nucleus [GO:0005634]; plasma membrane [GO:0005886] nuclear estrogen receptor binding [GO:0030331] 0.9589 -1.7851 EEEKNPEWLK 0 0 0 0 0 0 9.87739 10.2095 0 0 0 0 0 0 0 13.0503 0 0 0 0 0 0 0 0 0 0 0 Q8WXW3 PIBF1_HUMAN Progesterone-induced-blocking factor 1 (PIBF) (Centrosomal protein of 90 kDa) (CEP90) PIBF1 C13orf24 PIBF Homo sapiens (Human) activation of Janus kinase activity [GO:0042976]; cilium assembly [GO:0060271]; immune system process [GO:0002376]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of prostaglandin biosynthetic process [GO:0031393]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; non-motile cilium assembly [GO:1905515]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein localization to centrosome [GO:0071539] centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; nucleus [GO:0005634] interleukin-4 receptor binding [GO:0005136] 0.96947 -4.7079 DKEYLNRQNMELSVR 0 0 0 0 0 0 0 0 0 12.1312 9.1126 11.4465 0 0 0 0 15.9329 0 9.79084 0 0 0 0 10.5641 0 0 0 Q8WXX0 DYH7_HUMAN Dynein axonemal heavy chain 7 (Axonemal beta dynein heavy chain 7) (Ciliary dynein heavy chain 7) (Dynein heavy chain-like protein 2) (hDHC2) DNAH7 KIAA0944 Homo sapiens (Human) cilium movement [GO:0003341]; cilium-dependent cell motility [GO:0060285]; inner dynein arm assembly [GO:0036159] axonemal dynein complex [GO:0005858]; cilium [GO:0005929]; cytosol [GO:0005829]; inner dynein arm [GO:0036156]; microtubule [GO:0005874] ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; microtubule motor activity [GO:0003777]; minus-end-directed microtubule motor activity [GO:0008569] 0.96827 -9.4895 AINKAEWR 10.4614 0 0 10.0978 0 0 11.9668 9.01831 8.80503 9.83139 9.14952 0 10.7828 0 9.05696 12.1085 0 0 9.83618 9.15183 11.3069 0 0 8.70532 9.42568 9.39079 0 Q8WXX5 DNJC9_HUMAN DnaJ homolog subfamily C member 9 (HDJC9) (DnaJ protein SB73) DNAJC9 Homo sapiens (Human) nucleosome assembly [GO:0006334]; positive regulation of ATP-dependent activity [GO:0032781] cytoplasm [GO:0005737]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein folding chaperone complex [GO:0101031] heat shock protein binding [GO:0031072]; histone binding [GO:0042393]; protein-folding chaperone binding [GO:0051087] 0.94073 -1.3169 RRAQEEAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.66638 0 0 0 0 0 0 0 0 0 0 0 0 Q8WXX7 AUTS2_HUMAN Autism susceptibility gene 2 protein AUTS2 KIAA0442 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; axon extension [GO:0048675]; dendrite extension [GO:0097484]; neuron migration [GO:0001764]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H4-K16 acetylation [GO:2000620]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of Rac protein signal transduction [GO:0035022]; positive regulation of transcription by RNA polymerase II [GO:0045944] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; growth cone [GO:0030426]; nucleus [GO:0005634] chromatin binding [GO:0003682] 0.96876 -3.0107 DVDKRDSSVSK 0 0 0 0 0 0 0 0 0 0 0 0 9.26501 0 0 0 0 0 0 0 0 0 0 0 0 10.1631 0 Q8WY41 NANO1_HUMAN Nanos homolog 1 (NOS-1) (EC_Rep1a) NANOS1 NOS1 Homo sapiens (Human) "cell migration [GO:0016477]; cerebellar neuron development [GO:0098749]; epithelial cell migration [GO:0010631]; negative regulation of translation [GO:0017148]; oogenesis [GO:0048477]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of cell growth [GO:0001558]; tissue homeostasis [GO:0001894]" cytoplasm [GO:0005737]; perinuclear region of cytoplasm [GO:0048471] mRNA binding [GO:0003729]; translation repressor activity [GO:0030371]; zinc ion binding [GO:0008270] 0.0096618 1.7772 EAFPWAPR 0 0 0 10.0761 0 10.4764 0 0 0 12.5135 12.3879 12.4334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WY54 PPM1E_HUMAN Protein phosphatase 1E (EC 3.1.3.16) (Ca(2+)/calmodulin-dependent protein kinase phosphatase N) (CaMKP-N) (CaMKP-nucleus) (CaMKN) (Partner of PIX 1) (Partner of PIX-alpha) (Partner of PIXA) PPM1E CAMKN KIAA1072 POPX1 Homo sapiens (Human) cellular response to lipopolysaccharide [GO:0071222]; cellular response to xenobiotic stimulus [GO:0071466]; negative regulation of protein kinase activity [GO:0006469]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of stress fiber assembly [GO:0051496]; protein dephosphorylation [GO:0006470] mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991] metal ion binding [GO:0046872]; myosin phosphatase activity [GO:0017018]; protein serine/threonine phosphatase activity [GO:0004722] 0.96219 -2.5445 KTHDIPCPDLPWSYK 0 0 8.92935 0 10.5862 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.75365 0 0 0 0 Q8WY91 THAP4_HUMAN Peroxynitrite isomerase THAP4 (EC 5.99.-.-) (Ferric Homo sapiens nitrobindin) (Hs-Nb(III)) (THAP domain-containing protein 4) THAP4 CGI-36 PP238 Homo sapiens (Human) nitrate metabolic process [GO:0042126]; tyrosine metabolic process [GO:0006570] cytosol [GO:0005829]; nucleoplasm [GO:0005654] DNA binding [GO:0003677]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; peroxynitrite isomerase activity [GO:0062213] 0.84928 0.12207 GAGGHGR 12.1625 11.0061 10.8828 11.7061 0 11.6749 11.1163 11.144 10.8677 11.8382 11.9693 11.8336 0 0 0 0 0 0 0 0 0 0 10.939 0 0 0 0 Q8WYA0 IFT81_HUMAN Intraflagellar transport protein 81 homolog (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1) IFT81 CDV1 Homo sapiens (Human) cilium assembly [GO:0060271]; intraciliary anterograde transport [GO:0035720]; intraciliary transport [GO:0042073]; intraciliary transport involved in cilium assembly [GO:0035735]; regulation of smoothened signaling pathway [GO:0008589]; sperm flagellum assembly [GO:0120316]; spermatogenesis [GO:0007283] centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary tip [GO:0097542]; cilium [GO:0005929]; cytoplasm [GO:0005737]; intraciliary transport particle B [GO:0030992]; motile cilium [GO:0031514]; sperm midpiece [GO:0097225]; sperm principal piece [GO:0097228] tubulin binding [GO:0015631] 0.61247 0.42029 DLEQLMECK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.82979 0 0 0 0 0 0 0 0 0 0 0 Q8WYA1 BMAL2_HUMAN Basic helix-loop-helix ARNT-like protein 2 (Aryl hydrocarbon receptor nuclear translocator-like protein 2) (Basic-helix-loop-helix-PAS protein MOP9) (Brain and muscle ARNT-like 2) (CYCLE-like factor) (CLIF) (Class E basic helix-loop-helix protein 6) (bHLHe6) (Member of PAS protein 9) (PAS domain-containing protein 9) BMAL2 ARNTL2 BHLHE6 CLIF MOP9 PASD9 Homo sapiens (Human) circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; entrainment of circadian clock [GO:0009649]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; CLOCK-BMAL transcription complex [GO:1990513]; cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; E-box binding [GO:0070888]; protein dimerization activity [GO:0046983]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.89738 -0.52986 EKILTDSYKFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.067 0 0 0 0 0 0 0 Q8WYA6 CTBL1_HUMAN Beta-catenin-like protein 1 (Nuclear-associated protein) (NAP) (Testis development protein NYD-SP19) CTNNBL1 C20orf33 PP8304 Homo sapiens (Human) "adaptive immune response [GO:0002250]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of apoptotic process [GO:0043065]; somatic diversification of immunoglobulins [GO:0016445]" centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Prp19 complex [GO:0000974]; spliceosomal complex [GO:0005681] enzyme binding [GO:0019899] 0.92357 -1.0721 AKMPFDANK 0 0 0 9.86471 0 0 0 0 10.211 0 0 0 0 0 0 0 0 10.5669 0 0 0 0 0 9.35771 15.0097 0 0 Q8WYB5 KAT6B_HUMAN "Histone acetyltransferase KAT6B (EC 2.3.1.48) (Histone acetyltransferase MOZ2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (MYST-4) (Monocytic leukemia zinc finger protein-related factor)" KAT6B KIAA0383 MORF MOZ2 MYST4 Homo sapiens (Human) histone acetylation [GO:0016573]; negative regulation of DNA-templated transcription [GO:0045892]; nucleosome assembly [GO:0006334]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355]; regulation of hemopoiesis [GO:1903706] MOZ/MORF histone acetyltransferase complex [GO:0070776]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634] DNA binding [GO:0003677]; histone acetyltransferase activity [GO:0004402]; histone H3K14 acetyltransferase activity [GO:0036408]; metal ion binding [GO:0046872]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; transcription coactivator activity [GO:0003713] 0.96256 -2.4981 ANELDPDSLR 0 0 0 9.01092 0 9.35154 0 0 0 0 0 0 8.85807 9.09479 0 0 0 10.7045 0 0 0 0 0 8.8226 0 0 9.84323 Q8WYJ6 SEPT1_HUMAN Septin-1 (LARP) (Peanut-like protein 3) (Serologically defined breast cancer antigen NY-BR-24) SEPTIN1 DIFF6 PNUTL3 SEPT1 Homo sapiens (Human) cytoskeleton-dependent cytokinesis [GO:0061640]; meiotic metaphase plate congression [GO:0051311]; regulation of exocytosis [GO:0017157]; spindle assembly involved in female meiosis [GO:0007056] cell division site [GO:0032153]; meiotic spindle [GO:0072687]; microtubule cytoskeleton [GO:0015630]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; septin complex [GO:0031105]; septin ring [GO:0005940]; synaptic vesicle [GO:0008021] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; molecular adaptor activity [GO:0060090] 0.97023 -5.3353 AGGVMDK 11.0318 0 0 0 0 0 0 0 0 0 0 9.99803 0 0 0 0 0 0 0 0 0 0 10.0239 0 0 0 0 Q8WYK1 CNTP5_HUMAN Contactin-associated protein-like 5 (Cell recognition molecule Caspr5) CNTNAP5 CASPR5 Homo sapiens (Human) cell adhesion [GO:0007155] membrane [GO:0016020] 0.40945 0.69369 EPLTNAVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.71757 0 0 Q8WYK2 JDP2_HUMAN Jun dimerization protein 2 JDP2 Homo sapiens (Human) chromatin remodeling [GO:0006338]; fat cell differentiation [GO:0045444]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575] "cAMP response element binding [GO:0035497]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; histone chaperone activity [GO:0140713]; histone deacetylase binding [GO:0042826]; leucine zipper domain binding [GO:0043522]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.9595 -1.7419 LELMNAELKTQIEELKQER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2666 0 0 9.93344 0 0 0 Q8WYP5 ELYS_HUMAN Protein ELYS (Embryonic large molecule derived from yolk sac) (Protein MEL-28) (Putative AT-hook-containing transcription factor 1) AHCTF1 ELYS TMBS62 MSTP108 Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; mRNA transport [GO:0051028]; nuclear pore complex assembly [GO:0051292]; nucleocytoplasmic transport [GO:0006913]; protein transport [GO:0015031]; regulation of cytokinesis [GO:0032465] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; kinetochore [GO:0000776]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677] 0.96941 -3.9861 INVMNDRDPR 0 0 10.5024 0 0 0 0 0 0 0 0 0 0 9.78062 0 0 0 0 0 0 0 9.7617 0 0 0 0 0 Q8WYQ5 DGCR8_HUMAN Microprocessor complex subunit DGCR8 (DiGeorge syndrome critical region 8) DGCR8 C22orf12 DGCRK6 LP4941 Homo sapiens (Human) positive regulation of pre-miRNA processing [GO:2000633]; primary miRNA processing [GO:0031053]; regulation of stem cell proliferation [GO:0072091] cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; microprocessor complex [GO:0070877]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic density [GO:0014069] double-stranded RNA binding [GO:0003725]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; primary miRNA binding [GO:0070878]; protein homodimerization activity [GO:0042803]; protein-RNA adaptor activity [GO:0140517] 0.96288 -2.4428 EFVINPNGK 0 0 0 12.7934 0 0 8.68878 8.57701 0 0 0 0 0 0 9.95825 0 0 0 0 0 0 0 0 0 0 9.20266 0 Q8WYQ9 ZCH14_HUMAN Zinc finger CCHC domain-containing protein 14 (BDG-29) ZCCHC14 KIAA0579 Homo sapiens (Human) nucleic acid binding [GO:0003676]; phosphatidylinositol binding [GO:0035091]; zinc ion binding [GO:0008270] 0.96808 -2.7586 EESSDSAEENDRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.52939 0 0 9.34687 0 0 0 Q8WYR1 PI3R5_HUMAN "Phosphoinositide 3-kinase regulatory subunit 5 (PI3-kinase regulatory subunit 5) (PI3-kinase p101 subunit) (Phosphatidylinositol 4,5-bisphosphate 3-kinase regulatory subunit) (PtdIns-3-kinase regulatory subunit) (Protein FOAP-2) (PtdIns-3-kinase p101) (p101-PI3K)" PIK3R5 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551] "centriolar satellite [GO:0034451]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; phosphatidylinositol 3-kinase complex [GO:0005942]; phosphatidylinositol 3-kinase complex, class IA [GO:0005943]; phosphatidylinositol 3-kinase complex, class IB [GO:0005944]; plasma membrane [GO:0005886]" 1-phosphatidylinositol-3-kinase regulator activity [GO:0046935]; G-protein beta/gamma-subunit complex binding [GO:0031683] 0.96126 -2.0007 ASGPGSK 0 0 0 0 0 0 0 0 11.5325 0 13.9003 0 0 0 0 0 0 0 0 9.03881 0 0 0 0 11.2511 0 8.98014 Q8WZ19 BACD1_HUMAN BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 (hBACURD1) (BTB/POZ domain-containing protein KCTD13) (Polymerase delta-interacting protein 1) (TNFAIP1-like protein) KCTD13 BACURD1 PDIP1 POLDIP1 FKSG86 PP6832 Homo sapiens (Human) cell migration [GO:0016477]; negative regulation of Rho protein signal transduction [GO:0035024]; positive regulation of DNA replication [GO:0045740]; positive regulation of synaptic transmission [GO:0050806]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; stress fiber assembly [GO:0043149] Cul3-RING ubiquitin ligase complex [GO:0031463]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654] identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; small GTPase binding [GO:0031267] 0.84482 0.13458 ETLSPLCLIPMVTSPR 0 10.2476 0 0 0 10.0197 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WZ33 MAFIP_HUMAN MaFF-interacting protein (Tektin-4 like protein PP5644) MAFIP MIP PP5644 Homo sapiens (Human) cilium movement involved in cell motility [GO:0060294] cytoplasm [GO:0005737]; nucleolus [GO:0005730] 0.84402 0.13655 LLQAEQSLRNLKDIHMSLEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.6675 0 0 0 0 0 0 Q8WZ42 TITIN_HUMAN Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) TTN Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; protein phosphorylation [GO:0006468]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; striated muscle thin filament [GO:0005865]; titin-telethonin complex [GO:1990733]; Z disc [GO:0030018] actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433] 0.96922 -60.045 ACDPIYKPGPPNNPK 17.304 17.7632 15.6119 11.5457 14.7602 14.5187 16.7232 15.8128 16.2427 11.7383 13.6341 15.3501 16.1623 16.8864 15.7391 16.4088 16.3705 16.0925 0 12.1364 11.8157 12.083 12.9376 11.9884 16.2461 16.4295 16.5439 Q8WZ60 KLHL6_HUMAN Kelch-like protein 6 KLHL6 Homo sapiens (Human) B cell receptor signaling pathway [GO:0050853]; germinal center formation [GO:0002467]; response to bacterium [GO:0009617] 0.36638 0.74418 GVSHHGSVTIR 0 0 0 0 0 0 0 0 0 0 0 0 10.4748 0 10.0322 0 11.0389 0 0 0 0 9.06097 10.4716 0 10.3052 0 0 Q8WZ64 ARAP2_HUMAN "Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 (Centaurin-delta-1) (Cnt-d1) (Protein PARX)" ARAP2 CENTD1 KIAA0580 Homo sapiens (Human) positive regulation of GTPase activity [GO:0043547]; signal transduction [GO:0007165] cytoplasm [GO:0005737] "GTPase activator activity [GO:0005096]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]" 0.95304 -1.4857 ATLDSDHKLPSR 9.54498 0 0 0 0 0 0 0 0 0 0 0 0 10.2032 0 8.98297 9.47502 0 0 0 0 0 0 0 0 0 10.8872 Q8WZ73 RFFL_HUMAN E3 ubiquitin-protein ligase rififylin (EC 2.3.2.27) (Caspase regulator CARP2) (Caspases-8 and -10-associated RING finger protein 2) (CARP-2) (FYVE-RING finger protein Sakura) (Fring) (RING finger and FYVE-like domain-containing protein 1) (RING finger protein 189) (RING finger protein 34-like) (RING-type E3 ubiquitin transferase rififylin) RFFL RNF189 RNF34L Homo sapiens (Human) apoptotic process [GO:0006915]; negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:2001271]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; regulation of fibroblast migration [GO:0010762]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of TOR signaling [GO:0032006]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038] metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625] 0.92012 -0.90367 NFVNYKGCCEKWELMER 0 0 0 0 0 10.1693 0 9.00442 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WZ74 CTTB2_HUMAN Cortactin-binding protein 2 (CortBP2) CTTNBP2 C7orf8 CORTBP2 KIAA1758 Homo sapiens (Human) brain development [GO:0007420]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of synapse organization [GO:0050807] cell cortex [GO:0005938]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; postsynaptic actin cytoskeleton [GO:0098871]; synaptic vesicle [GO:0008021] SH3 domain binding [GO:0017124] 0.8854 -0.23283 EVFIQERYGR 0 0 10.0992 0 9.10886 0 0 10.3184 10.2359 11.1525 0 11.5921 0 0 0 0 0 10.086 0 0 0 0 11.0058 0 0 9.77416 10.4864 Q8WZ75 ROBO4_HUMAN Roundabout homolog 4 (Magic roundabout) ROBO4 UNQ421/PRO3674 Homo sapiens (Human) angiogenesis [GO:0001525]; axon guidance [GO:0007411]; dendrite self-avoidance [GO:0070593]; establishment of endothelial barrier [GO:0061028]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; regulation of cell migration [GO:0030334] axon [GO:0030424]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886] cell-cell adhesion mediator activity [GO:0098632]; signaling receptor activity [GO:0038023] 0.96275 -2.1669 MPKAGASPVDYS 8.85368 0 0 0 0 0 0 0 0 0 0 8.28327 0 0 0 0 0 0 8.95475 0 0 0 0 0 0 0 0 Q8WZ79 DNS2B_HUMAN Deoxyribonuclease-2-beta (EC 3.1.22.1) (DNase II-like acid DNase) (DNase2-like acid DNase) (Deoxyribonuclease II beta) (DNase II beta) (Endonuclease DLAD) DNASE2B DLAD Homo sapiens (Human) apoptotic DNA fragmentation [GO:0006309] extracellular region [GO:0005576]; lysosome [GO:0005764] deoxyribonuclease II activity [GO:0004531] 0.94091 -1.331 GTKNRWTCIGDLNR 0 0 0 9.63189 9.78498 9.48216 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WZ84 OR8D1_HUMAN Olfactory receptor 8D1 (OST004) (Olfactory receptor 8D3) (Olfactory receptor OR11-301) (Olfactory receptor-like protein JCG9) OR8D1 OR8D3 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; sensory perception of smell [GO:0007608] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; odorant binding [GO:0005549]; olfactory receptor activity [GO:0004984] 0.92017 -1.1426 SSEGRSK 0 0 0 0 0 0 0 0 0 8.48103 0 8.72226 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WZA0 LZIC_HUMAN Protein LZIC (Leucine zipper and CTNNBIP1 domain-containing protein) (Leucine zipper and ICAT homologous domain-containing protein) LZIC Homo sapiens (Human) negative regulation of Wnt signaling pathway [GO:0030178] beta-catenin binding [GO:0008013] 0.95248 -1.4556 LGEKLTADDEAFLSANAGAILSQFEK 0 0 0 0 0 0 0 0 0 0 10.8759 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WZA1 PMGT1_HUMAN "Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) (UDP-GlcNAc:alpha-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I.2) (GnT I.2)" POMGNT1 MGAT1.2 UNQ746/PRO1475 Homo sapiens (Human) basement membrane organization [GO:0071711]; dentate gyrus development [GO:0021542]; gene expression [GO:0010467]; O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493]; protein O-linked mannosylation [GO:0035269]; reactive gliosis [GO:0150103] Golgi membrane [GO:0000139]; membrane [GO:0016020] "acetylglucosaminyltransferase activity [GO:0008375]; beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity [GO:0047223]; manganese ion binding [GO:0030145]" 0.96343 -2.1135 RVLDVEVYSSR 0 0 0 0 0 0 0 0 9.72311 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q8WZA2 RPGF4_HUMAN Rap guanine nucleotide exchange factor 4 (Exchange factor directly activated by cAMP 2) (Exchange protein directly activated by cAMP 2) (EPAC 2) (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) RAPGEF4 CGEF2 EPAC2 Homo sapiens (Human) adaptive immune response [GO:0002250]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; calcium-ion regulated exocytosis [GO:0017156]; G protein-coupled receptor signaling pathway [GO:0007186]; insulin secretion [GO:0030073]; positive regulation of GTPase activity [GO:0043547]; positive regulation of insulin secretion [GO:0032024]; Ras protein signal transduction [GO:0007265]; regulation of exocytosis [GO:0017157]; regulation of synaptic vesicle cycle [GO:0098693] cytosol [GO:0005829]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; membrane [GO:0016020]; plasma membrane [GO:0005886] cAMP binding [GO:0030552]; GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; protein-macromolecule adaptor activity [GO:0030674]; small GTPase binding [GO:0031267] 0.9248 -0.97404 ELAGVLIFESHAK 11.7633 11.7199 11.1148 0 0 0 0 0 10.6649 9.49651 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92481 AP2B_HUMAN Transcription factor AP-2-beta (AP2-beta) (Activating enhancer-binding protein 2-beta) TFAP2B Homo sapiens (Human) anatomical structure development [GO:0048856]; aorta morphogenesis [GO:0035909]; collecting duct development [GO:0072044]; distal tubule development [GO:0072017]; ductus arteriosus closure [GO:0097070]; fat cell differentiation [GO:0045444]; forelimb morphogenesis [GO:0035136]; glucose metabolic process [GO:0006006]; hindlimb morphogenesis [GO:0035137]; kidney development [GO:0001822]; metanephric nephron development [GO:0072210]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron apoptotic process [GO:0051402]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of BMP signaling pathway [GO:0030510]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; regulation of insulin secretion [GO:0050796]; regulation of transcription by RNA polymerase II [GO:0006357]; response to xenobiotic stimulus [GO:0009410]; retina layer formation [GO:0010842]; skin development [GO:0043588]; smooth muscle tissue development [GO:0048745]; sympathetic nervous system development [GO:0048485]; transcription by RNA polymerase II [GO:0006366] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "chromatin binding [GO:0003682]; cis-regulatory region sequence-specific DNA binding [GO:0000987]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.91474 -0.80376 AVSEYLNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.69014 0 0 0 0 0 0 0 0 0 0 0 0 Q92482 AQP3_HUMAN Aquaporin-3 (AQP-3) (Aquaglyceroporin-3) AQP3 Homo sapiens (Human) cellular response to hypoxia [GO:0071456]; cellular response to oxygen-glucose deprivation [GO:0090650]; establishment of localization in cell [GO:0051649]; glycerol transmembrane transport [GO:0015793]; odontogenesis [GO:0042476]; positive regulation of immune system process [GO:0002684]; regulation of keratinocyte differentiation [GO:0045616]; renal water absorption [GO:0070295]; renal water homeostasis [GO:0003091]; response to calcium ion [GO:0051592]; response to retinoic acid [GO:0032526]; response to vitamin D [GO:0033280]; water transport [GO:0006833] basolateral plasma membrane [GO:0016323]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] glycerol channel activity [GO:0015254]; identical protein binding [GO:0042802]; urea transmembrane transporter activity [GO:0015204]; water channel activity [GO:0015250] 0.84994 0.11117 ELVSRCGEMLHIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3045 0 Q92499 DDX1_HUMAN ATP-dependent RNA helicase DDX1 (EC 3.6.4.13) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB) DDX1 Homo sapiens (Human) "defense response to virus [GO:0051607]; DNA duplex unwinding [GO:0032508]; double-strand break repair [GO:0006302]; innate immune response [GO:0045087]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myeloid dendritic cell cytokine production [GO:0002735]; protein localization to cytoplasmic stress granule [GO:1903608]; regulation of translational initiation [GO:0006446]; response to exogenous dsRNA [GO:0043330]; spliceosomal complex assembly [GO:0000245]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]" cleavage body [GO:0071920]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; tRNA-splicing ligase complex [GO:0072669] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA/RNA helicase activity [GO:0033677]; double-stranded RNA binding [GO:0003725]; exonuclease activity [GO:0004527]; nuclease activity [GO:0004518]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; transcription coregulator activity [GO:0003712] 0.54747 0.57371 DQQEGKKGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.69293 0 0 0 0 0 0 Q92503 S14L1_HUMAN SEC14-like protein 1 SEC14L1 SEC14L Homo sapiens (Human) choline transport [GO:0015871]; innate immune response [GO:0045087]; negative regulation of RIG-I signaling pathway [GO:0039536] cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654] molecular function inhibitor activity [GO:0140678]; protein sequestering activity [GO:0140311]; RIG-I binding [GO:0039552] 0.89686 -0.67456 GDIVFNIYHSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5298 0 0 0 0 Q92506 DHB8_HUMAN (3R)-3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12) (17-beta-hydroxysteroid dehydrogenase 8) (17-beta-HSD 8) (HSD17B8) (3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit) (KAR alpha subunit) (3-oxoacyl-[acyl-carrier-protein] reductase) (Estradiol 17-beta-dehydrogenase 8) (EC 1.1.1.62) (Protein Ke6) (Ke6) (Short chain dehydrogenase/reductase family 30C member 1) (Testosterone 17-beta-dehydrogenase 8) (EC 1.1.1.239) HSD17B8 FABGL HKE6 RING2 SDR30C1 Homo sapiens (Human) androgen metabolic process [GO:0008209]; estrogen biosynthetic process [GO:0006703]; fatty acid biosynthetic process [GO:0006633]; protein heterotetramerization [GO:0051290] mitochondrial envelope [GO:0005740]; mitochondrial matrix [GO:0005759]; oxidoreductase complex [GO:1990204]; plasma membrane [GO:0005886] (3R)-hydroxyacyl-CoA dehydrogenase (NAD) activity [GO:0106386]; 17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; estradiol 17-beta-dehydrogenase [NAD(P)] activity [GO:0004303]; NADH binding [GO:0070404]; testosterone dehydrogenase (NAD+) activity [GO:0047035] 0.83606 0.19415 VGNVGQTNYAASK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.90194 0 0 0 0 0 0 0 0 0 0 Q92520 FAM3C_HUMAN Protein FAM3C (Interleukin-like EMT inducer) FAM3C ILEI GS3786 Homo sapiens (Human) extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; platelet dense granule lumen [GO:0031089] cytokine activity [GO:0005125] 0.93983 -1.3235 SPFEQHIKNNK 0 0 0 9.66789 0 9.20579 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92522 H1X_HUMAN Histone H1.10 (Histone H1x) H1-10 H1FX Homo sapiens (Human) chromosome condensation [GO:0030261]; negative regulation of DNA recombination [GO:0045910]; nucleosome assembly [GO:0006334] nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634] cadherin binding [GO:0045296]; double-stranded DNA binding [GO:0003690]; nucleosomal DNA binding [GO:0031492]; RNA binding [GO:0003723]; structural constituent of chromatin [GO:0030527] 0.55814 0.5481 LEGGGER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2871 0 10.2596 0 0 0 0 0 0 Q92523 CPT1B_HUMAN "Carnitine O-palmitoyltransferase 1, muscle isoform (CPT1-M) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, muscle isoform) (CPT I) (CPTI-M) (Carnitine palmitoyltransferase 1B) (Carnitine palmitoyltransferase I-like protein)" CPT1B KIAA1670 Homo sapiens (Human) carnitine metabolic process [GO:0009437]; carnitine shuttle [GO:0006853]; fatty acid beta-oxidation [GO:0006635]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; response to blue light [GO:0009637] mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739] carnitine O-palmitoyltransferase activity [GO:0004095] 0.96412 -2.3873 EFQDKTAPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7093 0 0 0 0 0 Q92529 SHC3_HUMAN SHC-transforming protein 3 (Neuronal Shc) (N-Shc) (Protein Rai) (SHC-transforming protein C) (Src homology 2 domain-containing-transforming protein C3) (SH2 domain protein C3) SHC3 NSHC SHCC Homo sapiens (Human) central nervous system development [GO:0007417]; epidermal growth factor receptor signaling pathway [GO:0007173]; intracellular signal transduction [GO:0035556]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] cytosol [GO:0005829]; plasma membrane [GO:0005886] phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971] 0.88306 -0.038244 AASVECISPVSPR 0 0 0 0 0 0 0 0 0 0 0 0 9.3415 9.23496 0 0 9.20215 0 0 0 0 0 0 0 0 10.6325 0 Q92540 SMG7_HUMAN Nonsense-mediated mRNA decay factor SMG7 (SMG-7 homolog) (hSMG-7) SMG7 C1orf16 EST1C KIAA0250 Homo sapiens (Human) "mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of dephosphorylation [GO:0035303]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; telomerase holoenzyme complex [GO:0005697] protein phosphatase 2A binding [GO:0051721]; telomerase RNA binding [GO:0070034]; telomeric DNA binding [GO:0042162] 0.92218 -1.1213 ALESRDEVK 0 0 0 0 0 0 10.6515 0 10.8549 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.6263 Q92541 RTF1_HUMAN RNA polymerase-associated protein RTF1 homolog RTF1 KIAA0252 Homo sapiens (Human) blastocyst growth [GO:0001832]; endodermal cell fate commitment [GO:0001711]; negative regulation of transcription by RNA polymerase II [GO:0000122]; stem cell population maintenance [GO:0019827]; transcription elongation by RNA polymerase II [GO:0006368]; Wnt signaling pathway [GO:0016055] Cdc73/Paf1 complex [GO:0016593]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697] 0.95821 -1.6697 LDKKSQAMEELK 9.18361 8.96012 0 0 0 0 0 0 0 0 0 8.70134 0 0 0 0 0 0 0 0 0 0 9.21216 0 10.0003 0 0 Q92542 NICA_HUMAN Nicastrin NCSTN KIAA0253 UNQ1874/PRO4317 Homo sapiens (Human) adult behavior [GO:0030534]; amyloid precursor protein biosynthetic process [GO:0042983]; amyloid precursor protein catabolic process [GO:0042987]; amyloid precursor protein metabolic process [GO:0042982]; amyloid-beta formation [GO:0034205]; cellular response to calcium ion [GO:0071277]; central nervous system myelination [GO:0022010]; cerebellum development [GO:0021549]; dopamine receptor signaling pathway [GO:0007212]; epithelial cell proliferation [GO:0050673]; glutamate receptor signaling pathway [GO:0007215]; learning or memory [GO:0007611]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; myeloid cell homeostasis [GO:0002262]; neuron apoptotic process [GO:0051402]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; positive regulation of amyloid precursor protein biosynthetic process [GO:0042986]; positive regulation of catalytic activity [GO:0043085]; positive regulation of endopeptidase activity [GO:0010950]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of long-term synaptic potentiation [GO:1900271]; short-term synaptic potentiation [GO:1990926]; T cell proliferation [GO:0042098] azurophil granule membrane [GO:0035577]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; gamma-secretase complex [GO:0070765]; Golgi apparatus [GO:0005794]; lysosomal membrane [GO:0005765]; melanosome [GO:0042470]; membrane [GO:0016020]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; sarcolemma [GO:0042383]; synaptic vesicle [GO:0008021] "aspartic endopeptidase activity, intramembrane cleaving [GO:0042500]; ATPase binding [GO:0051117]; growth factor receptor binding [GO:0070851]; protein-macromolecule adaptor activity [GO:0030674]" 0.5635 0.49542 ADVLFIAPR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1896 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92543 SNX19_HUMAN Sorting nexin-19 SNX19 KIAA0254 Homo sapiens (Human) chondrocyte differentiation [GO:0002062]; dense core granule maturation [GO:1990502]; establishment of localization in cell [GO:0051649]; exocytosis [GO:0006887]; insulin secretion [GO:0030073] cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; intracellular membrane-bounded organelle [GO:0043231] phosphatidylinositol binding [GO:0035091] 0.87029 0.046607 LEEKPDLR 0 0 0 0 0 0 0 0 0 0 9.88203 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92544 TM9S4_HUMAN Transmembrane 9 superfamily member 4 (Tumor cannibalism associated protein 1) TM9SF4 KIAA0255 TUCAP1 Homo sapiens (Human) cell adhesion [GO:0007155]; phagocytosis [GO:0006909]; positive regulation of protein exit from endoplasmic reticulum [GO:0070863]; positive regulation of protein localization to cell surface [GO:2000010]; protein localization to membrane [GO:0072657]; regulation of intracellular pH [GO:0051453]; response to hypoxia [GO:0001666]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072] early endosome [GO:0005769]; Golgi apparatus [GO:0005794]; membrane [GO:0016020] 0.96289 -2.1777 FEVIPQSIR 8.63165 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.58605 0 0 Q92545 TM131_HUMAN Transmembrane protein 131 (Protein RW1) TMEM131 KIAA0257 RW1 Homo sapiens (Human) membrane [GO:0016020] 0.96547 -2.2906 AASLPGK 0 0 0 0 0 0 0 0 10.0344 8.8755 0 0 0 9.69148 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92547 TOPB1_HUMAN DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-beta-binding protein 1) (TopBP1) (DNA topoisomerase II-binding protein 1) TOPBP1 KIAA0259 Homo sapiens (Human) DNA damage response [GO:0006974]; DNA metabolic process [GO:0006259]; DNA repair [GO:0006281]; DNA replication initiation [GO:0006270]; homologous recombination [GO:0035825]; mitotic DNA replication checkpoint signaling [GO:0033314]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; response to ionizing radiation [GO:0010212] actin cytoskeleton [GO:0015629]; BRCA1-B complex [GO:0070532]; chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; cytoplasm [GO:0005737]; male germ cell nucleus [GO:0001673]; microtubule organizing center [GO:0005815]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; spindle pole [GO:0000922] DNA binding [GO:0003677]; identical protein binding [GO:0042802] 0.93241 -1.2595 FLKSSDNSKCFFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4116 0 0 0 0 0 0 0 Q92552 RT27_HUMAN "Small ribosomal subunit protein mS27 (28S ribosomal protein S27, mitochondrial) (MRP-S27) (S27mt) (Mitochondrial ribosomal protein S27)" MRPS27 KIAA0264 Homo sapiens (Human) cell population proliferation [GO:0008283]; mitochondrial translation [GO:0032543]; positive regulation of mitochondrial translation [GO:0070131] cytoplasm [GO:0005737]; mitochondrial inner membrane [GO:0005743]; mitochondrial small ribosomal subunit [GO:0005763]; mitochondrion [GO:0005739]; nucleolus [GO:0005730] mitochondrial ribosome binding [GO:0097177]; rRNA binding [GO:0019843]; tRNA binding [GO:0000049] 0.34913 0.76652 EALDVLGAVLK 0 8.49801 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.33579 0 0 Q92558 WASF1_HUMAN Actin-binding protein WASF1 (Protein WAVE-1) (Verprolin homology domain-containing protein 1) (Wiskott-Aldrich syndrome protein family member 1) (WASP family protein member 1) WASF1 KIAA0269 SCAR1 WAVE1 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament polymerization [GO:0030041]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; dendrite extension [GO:0097484]; dendritic transport of mitochondrion [GO:0098939]; lamellipodium morphogenesis [GO:0072673]; mitochondrion morphogenesis [GO:0070584]; modification of postsynaptic actin cytoskeleton [GO:0098885]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; positive regulation of neurotrophin TRK receptor signaling pathway [GO:0051388]; protein-containing complex assembly [GO:0065003]; Rac protein signal transduction [GO:0016601]; receptor-mediated endocytosis [GO:0006898] actin cytoskeleton [GO:0015629]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; mitochondrial outer membrane [GO:0005741]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]; SCAR complex [GO:0031209] actin binding [GO:0003779]; Arp2/3 complex binding [GO:0071933]; protein kinase A binding [GO:0051018]; protein kinase A regulatory subunit binding [GO:0034237] 0.81322 0.22176 NIDPRHLCHTALPRGIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.24308 0 0 Q92561 PHYIP_HUMAN Phytanoyl-CoA hydroxylase-interacting protein (Phytanoyl-CoA hydroxylase-associated protein 1) (PAHX-AP1) (PAHXAP1) PHYHIP DYRK1AP3 KIAA0273 Homo sapiens (Human) protein localization [GO:0008104] cytoplasm [GO:0005737] protein tyrosine kinase binding [GO:1990782] 0.88252 -0.091709 VTHYFIDLNKKENK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.95175 0 0 Q92562 FIG4_HUMAN "Polyphosphoinositide phosphatase (EC 3.1.3.-) (EC 3.1.3.36) (EC 3.1.3.86) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase) (SAC domain-containing protein 3) (Serine-protein phosphatase FIG4) (EC 3.1.3.16)" FIG4 KIAA0274 SAC3 Homo sapiens (Human) locomotory behavior [GO:0007626]; myelin assembly [GO:0032288]; negative regulation of myelination [GO:0031642]; neuron development [GO:0048666]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; pigmentation [GO:0043473]; positive regulation of neuron projection development [GO:0010976]; vacuole organization [GO:0007033] early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; lipid droplet [GO:0005811]; recycling endosome [GO:0055037] "phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity [GO:0034485]; phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity [GO:0043813]; phosphatidylinositol-3-phosphate phosphatase activity [GO:0004438]; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity [GO:0004439]; phosphatidylinositol-4-phosphate phosphatase activity [GO:0043812]; protein serine/threonine phosphatase activity [GO:0004722]" 0.95995 -1.9326 DIMQTLSRYYSNAFSDADR 0 0 0 0 0 0 0 9.36848 0 0 12.1032 9.02998 0 0 0 9.98042 0 0 0 0 0 8.64281 8.57357 0 9.84111 0 0 Q92564 DCNL4_HUMAN DCN1-like protein 4 (DCNL4) (DCUN1 domain-containing protein 4) (Defective in cullin neddylation protein 1-like protein 4) DCUN1D4 KIAA0276 Homo sapiens (Human) positive regulation of protein neddylation [GO:2000436]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein neddylation [GO:0045116] nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151] cullin family protein binding [GO:0097602]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin-like protein binding [GO:0032182] 0.82944 0.20561 SLDINTAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.46854 0 0 0 0 0 0 0 0 0 0 0 Q92565 RPGF5_HUMAN Rap guanine nucleotide exchange factor 5 (Guanine nucleotide exchange factor for Rap1) (M-Ras-regulated Rap GEF) (MR-GEF) (Related to Epac) (Repac) RAPGEF5 GFR KIAA0277 MRGEF Homo sapiens (Human) nervous system development [GO:0007399]; positive regulation of GTPase activity [GO:0043547]; Ras protein signal transduction [GO:0007265]; small GTPase mediated signal transduction [GO:0007264] nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] GTP-dependent protein binding [GO:0030742]; guanyl-nucleotide exchange factor activity [GO:0005085] 0.9057 -0.72594 AKVSSIAQEILK 0 0 0 0 0 0 0 9.99901 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92570 NR4A3_HUMAN Nuclear receptor subfamily 4 group A member 3 (Mitogen-induced nuclear orphan receptor) (Neuron-derived orphan receptor 1) (Nuclear hormone receptor NOR-1) NR4A3 CHN CSMF MINOR NOR1 TEC Homo sapiens (Human) animal organ regeneration [GO:0031100]; cellular respiration [GO:0045333]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to corticotropin-releasing hormone stimulus [GO:0071376]; cellular response to leptin stimulus [GO:0044320]; common myeloid progenitor cell proliferation [GO:0035726]; energy homeostasis [GO:0097009]; fat cell differentiation [GO:0045444]; gastrulation [GO:0007369]; intracellular signal transduction [GO:0035556]; mast cell degranulation [GO:0043303]; negative regulation of transcription by RNA polymerase II [GO:0000122]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of fatty acid oxidation [GO:0046321]; positive regulation of feeding behavior [GO:2000253]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway [GO:0038097]; positive regulation of mast cell cytokine production [GO:0032765]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; pyruvate oxidation [GO:0009444]; regulation of smooth muscle cell proliferation [GO:0048660]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of type B pancreatic cell proliferation [GO:0061469] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "cAMP response element binding [GO:0035497]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; nuclear glucocorticoid receptor binding [GO:0035259]; nuclear receptor activity [GO:0004879]; nuclear steroid receptor activity [GO:0003707]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; zinc ion binding [GO:0008270]" 0.96149 -2.5714 IPGFTDLPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.70157 10.201 9.15747 0 0 0 0 Q92575 UBXN4_HUMAN UBX domain-containing protein 4 (Erasin) (UBX domain-containing protein 2) UBXN4 KIAA0242 UBXD2 UBXDC1 Homo sapiens (Human) response to unfolded protein [GO:0006986]; ubiquitin-dependent ERAD pathway [GO:0030433] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nuclear envelope [GO:0005635] 0.95196 -1.4262 EFTKEDYKK 9.75862 9.82203 9.55607 0 0 8.69919 0 9.38985 9.07205 12.0979 11.576 0 0 0 0 0 0 8.82572 0 0 0 0 0 0 0 0 0 Q92576 PHF3_HUMAN PHD finger protein 3 PHF3 KIAA0244 Homo sapiens (Human) DNA-templated transcription [GO:0006351] nucleus [GO:0005634] metal ion binding [GO:0046872] 0.88491 -0.23603 EEVCMSLKPEYHKENR 0 0 0 0 9.09592 0 9.4028 0 10.8509 0 10.0505 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92581 SL9A6_HUMAN Sodium/hydrogen exchanger 6 (Na(+)/H(+) exchanger 6) (NHE-6) (Solute carrier family 9 member 6) SLC9A6 KIAA0267 NHE6 Homo sapiens (Human) axon extension [GO:0048675]; dendrite extension [GO:0097484]; establishment of cell polarity [GO:0030010]; monoatomic ion transport [GO:0006811]; neuron projection morphogenesis [GO:0048812]; potassium ion transmembrane transport [GO:0071805]; regulation of intracellular pH [GO:0051453]; sodium ion import across plasma membrane [GO:0098719] early endosome membrane [GO:0031901]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038] identical protein binding [GO:0042802]; potassium:proton antiporter activity [GO:0015386]; sodium:proton antiporter activity [GO:0015385] 0.72768 0.3443 AESAWLFR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.43454 0 0 0 10.6573 0 0 0 0 0 0 0 0 0 Q92585 MAML1_HUMAN Mastermind-like protein 1 (Mam-1) MAML1 KIAA0200 Homo sapiens (Human) atrioventricular node cell development [GO:0060928]; atrioventricular node development [GO:0003162]; myoblast differentiation [GO:0045445]; Notch signaling pathway [GO:0007219]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; protein phosphorylation [GO:0006468] MAML1-RBP-Jkappa- ICN1 complex [GO:0002193]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] peptide antigen binding [GO:0042605]; protein kinase binding [GO:0019901]; transcription coactivator activity [GO:0003713] 0.33119 0.77865 DLFNEDFEEKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.62251 0 0 0 0 0 0 0 0 0 8.94146 0 0 Q92597 NDRG1_HUMAN Protein NDRG1 (Differentiation-related gene 1 protein) (DRG-1) (N-myc downstream-regulated gene 1 protein) (Nickel-specific induction protein Cap43) (Reducing agents and tunicamycin-responsive protein) (RTP) (Rit42) NDRG1 CAP43 DRG1 RTP Homo sapiens (Human) "cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; mast cell activation [GO:0045576]; negative regulation of cell population proliferation [GO:0008285]; peripheral nervous system myelin maintenance [GO:0032287]; response to metal ion [GO:0010038]; signal transduction [GO:0007165]" adherens junction [GO:0005912]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038] cadherin binding [GO:0045296]; gamma-tubulin binding [GO:0043015]; microtubule binding [GO:0008017]; small GTPase binding [GO:0031267] 0.020833 1.6364 TASGSSVTSLDGTR 0 0 0 0 0 0 0 8.36357 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92598 HS105_HUMAN Heat shock protein 105 kDa (Antigen NY-CO-25) (Heat shock 110 kDa protein) HSPH1 HSP105 HSP110 KIAA0201 Homo sapiens (Human) chaperone cofactor-dependent protein refolding [GO:0051085]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NK T cell activation [GO:0051135]; protein folding [GO:0006457]; response to unfolded protein [GO:0006986] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] adenyl-nucleotide exchange factor activity [GO:0000774]; alpha-tubulin binding [GO:0043014]; ATP binding [GO:0005524]; ATP-dependent protein folding chaperone [GO:0140662] 0 14.16 AFNDPFIQK 0 0 0 0 0 0 0 0 0 11.3144 10.7624 10.7968 0 0 0 10.0426 0 0 0 0 0 0 0 0 0 0 0 Q92599 SEPT8_HUMAN Septin-8 SEPTIN8 KIAA0202 SEPT8 Homo sapiens (Human) cytoskeleton-dependent cytokinesis [GO:0061640]; regulation of intracellular protein transport [GO:0033157]; regulation of protein stability [GO:0031647]; regulation of SNARE complex assembly [GO:0035542] axon [GO:0030424]; cell division site [GO:0032153]; microtubule cytoskeleton [GO:0015630]; presynapse [GO:0098793]; septin complex [GO:0031105]; septin ring [GO:0005940]; synaptic vesicle membrane [GO:0030672] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; molecular adaptor activity [GO:0060090] 0.96986 -3.1093 ERELHEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2529 0 0 0 0 0 0 0 Q92604 LGAT1_HUMAN Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (2-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.62) (Acyl-CoA:monoacylglycerol acyltransferase LPGAT1) (EC 2.3.1.22) (Lysophospholipid acyltransferase 7) (LPLAT7) (EC 2.3.1.-) (Stearoyl-CoA:1-lyso-2-acyl-PE acyltransferase) LPGAT1 FAM34A KIAA0205 Homo sapiens (Human) phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phospholipid biosynthetic process [GO:0008654]; positive regulation of fatty acid biosynthetic process [GO:0045723]; triglyceride biosynthetic process [GO:0019432] cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] 1-acylglycerol-3-phosphate O-acyltransferase activity [GO:0003841]; 2-acylglycerol O-acyltransferase activity [GO:0003846]; 2-acylglycerol-3-phosphate O-acyltransferase activity [GO:0047144]; 2-acylglycerophosphocholine O-acyltransferase activity [GO:0047190]; acyltransferase activity [GO:0016746]; lysophosphatidylethanolamine acyltransferase activity [GO:0071618]; lysophospholipid acyltransferase activity [GO:0071617] 0.90539 -0.72609 EDLLSHFYETGAFPPSK 0 0 0 0 10.2783 0 0 0 0 10.3528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92608 DOCK2_HUMAN Dedicator of cytokinesis protein 2 DOCK2 KIAA0209 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; alpha-beta T cell proliferation [GO:0046633]; cell migration [GO:0016477]; chemotaxis [GO:0006935]; establishment of T cell polarity [GO:0001768]; immunological synapse formation [GO:0001771]; macropinocytosis [GO:0044351]; membrane raft polarization [GO:0001766]; myeloid dendritic cell activation involved in immune response [GO:0002277]; myoblast fusion [GO:0007520]; negative thymic T cell selection [GO:0045060]; positive regulation of phagocytosis [GO:0050766]; positive thymic T cell selection [GO:0045059]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule lumen [GO:0035580] GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; small GTPase binding [GO:0031267]; T cell receptor binding [GO:0042608] 0.96912 -5.7529 EMPDFDDR 0 0 0 0 0 0 0 10.1179 8.94717 10.0441 0 0 0 10.8672 11.1034 0 0 10.3814 0 0 0 0 0 0 10.5557 0 0 Q92609 TBCD5_HUMAN TBC1 domain family member 5 TBC1D5 KIAA0210 Homo sapiens (Human) "activation of GTPase activity [GO:0090630]; autophagy [GO:0006914]; macroautophagy [GO:0016236]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; response to starvation [GO:0042594]; retrograde transport, endosome to Golgi [GO:0042147]" autophagosome [GO:0005776]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; retromer complex [GO:0030904] AP-2 adaptor complex binding [GO:0035612]; GTPase activator activity [GO:0005096]; protein-containing complex binding [GO:0044877]; retromer complex binding [GO:1905394] 0.65307 0.39575 GADLMNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.43225 0 0 0 0 0 0 0 Q92610 ZN592_HUMAN Zinc finger protein 592 ZNF592 KIAA0211 Homo sapiens (Human) negative regulation of insulin receptor signaling pathway [GO:0046627]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730] nucleus [GO:0005634] DNA binding [GO:0003677]; insulin receptor substrate binding [GO:0043560]; metal ion binding [GO:0046872]; PH domain binding [GO:0042731] 0.96529 -2.7118 KGDESMTKASDSSSPSCSSGPR 0 0 0 0 0 0 0 0 0 0 9.05444 0 0 0 0 0 0 0 0 0 0 9.84259 0 9.82731 0 0 0 Q92611 EDEM1_HUMAN ER degradation-enhancing alpha-mannosidase-like protein 1 EDEM1 EDEM KIAA0212 Homo sapiens (Human) "carbohydrate metabolic process [GO:0005975]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; positive regulation of retrograde protein transport, ER to cytosol [GO:1904154]; protein targeting to ER [GO:0045047]; response to unfolded protein [GO:0006986]; trimming of terminal mannose on C branch [GO:0036510]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent glycoprotein ERAD pathway [GO:0097466]" aggresome [GO:0016235]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum quality control compartment [GO:0044322] "calcium ion binding [GO:0005509]; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [GO:0004571]; misfolded protein binding [GO:0051787]" 0.55912 0.5174 IITDSKQPFGDMTIK 10.3441 10.2765 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92614 MY18A_HUMAN Unconventional myosin-XVIIIa (Molecule associated with JAK3 N-terminus) (MAJN) (Myosin containing a PDZ domain) (Surfactant protein receptor SP-R210) (SP-R210) MYO18A CD245 KIAA0216 MYSPDZ TIAF1 Homo sapiens (Human) actomyosin structure organization [GO:0031032]; asymmetric Golgi ribbon formation [GO:0090164]; cell migration [GO:0016477]; DNA metabolic process [GO:0006259]; Golgi organization [GO:0007030]; Golgi ribbon formation [GO:0090161]; Golgi vesicle budding [GO:0048194]; negative regulation of apoptotic process [GO:0043066]; positive regulation of opsonization [GO:1903028]; positive regulation of protein secretion [GO:0050714]; regulation of macrophage activation [GO:0043030] actomyosin [GO:0042641]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; myosin filament [GO:0032982]; myosin II complex [GO:0016460]; trans-Golgi network [GO:0005802] "actin filament binding [GO:0051015]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATP-dependent activity, acting on DNA [GO:0008094]; DNA binding [GO:0003677]; RNA binding [GO:0003723]" 0.96978 -5.4295 ELQTQYDALK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5228 0 0 0 0 9.87284 0 0 0 11.1529 Q92615 LAR4B_HUMAN La-related protein 4B (La ribonucleoprotein domain family member 4B) (La ribonucleoprotein domain family member 5) (La-related protein 5) LARP4B KIAA0217 LARP5 Homo sapiens (Human) positive regulation of 3'-UTR-mediated mRNA stabilization [GO:1905870]; positive regulation of translation [GO:0045727] cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleolus [GO:0005730]; polysomal ribosome [GO:0042788] mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723] 0.83291 0.19884 TLEFCLSR 0 0 8.98197 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92616 GCN1_HUMAN Stalled ribosome sensor GCN1 (GCN1 eIF-2-alpha kinase activator homolog) (GCN1-like protein 1) (General control of amino-acid synthesis 1-like protein 1) (Translational activator GCN1) (HsGCN1) GCN1 GCN1L1 KIAA0219 Homo sapiens (Human) cellular response to amino acid starvation [GO:0034198]; cellular response to leucine starvation [GO:1990253]; GCN2-mediated signaling [GO:0140469]; regulation of translation [GO:0006417]; rescue of stalled ribosome [GO:0072344] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; membrane [GO:0016020]; polysome [GO:0005844]; ribosome [GO:0005840] "cadherin binding [GO:0045296]; molecular adaptor activity [GO:0060090]; protein kinase regulator activity [GO:0019887]; protein serine/threonine kinase activator activity [GO:0043539]; RNA binding [GO:0003723]; stalled ribosome sensor activity [GO:0170011]; translation factor activity, RNA binding [GO:0008135]; ubiquitin-protein transferase activator activity [GO:0097027]" 0.92014 -0.92861 AKRQGDIWNK 11.6969 0 0 0 0 0 0 11.3787 0 0 0 0 0 0 0 9.79007 0 10.6102 0 0 0 9.53576 0 0 10.2478 11.7131 10.0318 Q92618 ZN516_HUMAN Zinc finger protein 516 ZNF516 KIAA0222 Homo sapiens (Human) adipose tissue development [GO:0060612]; brown fat cell differentiation [GO:0050873]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription [GO:0006355]; response to cold [GO:0009409] nucleus [GO:0005634] "cis-regulatory region sequence-specific DNA binding [GO:0000987]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription factor binding [GO:0140297]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.91944 -0.90927 MDRNREAEMELR 10.701 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.16513 0 0 0 0 0 0 0 0 0 Q92619 HMHA1_HUMAN Rho GTPase-activating protein 45 [Cleaved into: Minor histocompatibility antigen HA-1 (mHag HA-1)] ARHGAP45 HMHA1 KIAA0223 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] azurophil granule lumen [GO:0035578]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; secretory granule lumen [GO:0034774] GTPase activator activity [GO:0005096]; metal ion binding [GO:0046872] 0.9677 -2.899 AEAEAKAASRGR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.82871 0 9.81117 0 0 0 0 0 0 0 0 0 0 0 Q92620 PRP16_HUMAN Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.4.13) (ATP-dependent RNA helicase DHX38) (DEAH box protein 38) DHX38 DDX38 KIAA0224 PRP16 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]" catalytic step 2 spliceosome [GO:0071013]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681] 3'-5' RNA helicase activity [GO:0034458]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.96951 -6.3025 DAATPSR 0 9.43935 0 8.62673 0 10.8027 0 0 0 0 0 0 0 0 0 8.43605 8.37191 0 0 0 0 0 0 0 10.7765 0 0 Q92621 NU205_HUMAN Nuclear pore complex protein Nup205 (205 kDa nucleoporin) (Nucleoporin Nup205) NUP205 C7orf14 KIAA0225 Homo sapiens (Human) mRNA transport [GO:0051028]; nuclear pore complex assembly [GO:0051292]; nuclear pore organization [GO:0006999]; nucleocytoplasmic transport [GO:0006913]; protein transport [GO:0015031] cytosol [GO:0005829]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear periphery [GO:0034399]; nuclear pore [GO:0005643]; nuclear pore inner ring [GO:0044611] structural constituent of nuclear pore [GO:0017056] 0.96957 -4.4183 FQRQCLGLLSR 0 0 0 0 0 0 0 0 0 0 0 11.9514 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92622 RUBIC_HUMAN Run domain Beclin-1-interacting and cysteine-rich domain-containing protein (Rubicon) (Beclin-1 associated RUN domain containing protein) (Baron) RUBCN KIAA0226 Homo sapiens (Human) autophagy [GO:0006914]; immune system process [GO:0002376]; multivesicular body sorting pathway [GO:0071985]; negative regulation of autophagosome maturation [GO:1901097]; negative regulation of autophagy [GO:0010507]; negative regulation of endocytosis [GO:0045806]; negative regulation of phosphatidylinositol 3-kinase activity [GO:0043553]; phagocytosis [GO:0006909] cytosol [GO:0005829]; early endosome [GO:0005769]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosome [GO:0005764]; nucleoplasm [GO:0005654] phosphatidylinositol phosphate binding [GO:1901981] 0.88095 0.013984 LLRVQLCHMK 0 0 0 0 0 0 0 0 0 8.43817 10.1358 10.1193 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92624 APBP2_HUMAN Amyloid protein-binding protein 2 (Amyloid beta precursor protein-binding protein 2) (APP-BP2) (Protein interacting with APP tail 1) APPBP2 KIAA0228 PAT1 Homo sapiens (Human) intracellular protein transport [GO:0006886]; intracellular transport [GO:0046907]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567] Cul2-RING ubiquitin ligase complex [GO:0031462]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] microtubule motor activity [GO:0003777]; ubiquitin ligase-substrate adaptor activity [GO:1990756] 0.8828 -0.26756 AVECCVR 0 0 0 0 0 0 0 0 0 8.73037 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92625 ANS1A_HUMAN Ankyrin repeat and SAM domain-containing protein 1A (Odin) ANKS1A ANKS1 KIAA0229 ODIN Homo sapiens (Human) ephrin receptor signaling pathway [GO:0048013]; neuron remodeling [GO:0016322]; substrate-dependent cell migration [GO:0006929] cytosol [GO:0005829]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654] ephrin receptor binding [GO:0046875] 0.93035 -1.2475 GCYPLHLAAWK 0 0 0 0 0 0 8.81724 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92626 PXDN_HUMAN Peroxidasin homolog (EC 1.11.2.-) (Melanoma-associated antigen MG50) (Peroxidasin 1) (hsPxd01) (Vascular peroxidase 1) (p53-responsive gene 2 protein) [Cleaved into: PXDN active fragment] PXDN KIAA0230 MG50 PRG2 PXD01 VPO VPO1 Homo sapiens (Human) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; immune response [GO:0006955]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] basement membrane [GO:0005604]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] "extracellular matrix structural constituent [GO:0005201]; heme binding [GO:0020037]; interleukin-1 receptor antagonist activity [GO:0005152]; lactoperoxidase activity [GO:0140825]; laminin-1 binding [GO:0043237]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peroxidase activity [GO:0004601]" 0.079151 1.237 IVNEGGIDPLLR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6519 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92628 K0232_HUMAN Uncharacterized protein KIAA0232 KIAA0232 Homo sapiens (Human) ATP binding [GO:0005524] 0.9609 -2.0065 DLYMENRK 0 0 0 0 0 9.36337 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92629 SGCD_HUMAN Delta-sarcoglycan (Delta-SG) (35 kDa dystrophin-associated glycoprotein) (35DAG) SGCD Homo sapiens (Human) calcium ion homeostasis [GO:0055074]; calcium-mediated signaling [GO:0019722]; cardiac muscle cell contraction [GO:0086003]; cardiac muscle cell development [GO:0055013]; cardiac muscle tissue development [GO:0048738]; coronary vasculature morphogenesis [GO:0060977]; heart contraction [GO:0060047]; muscle organ development [GO:0007517]; protein-containing complex localization [GO:0031503] cytoskeleton [GO:0005856]; dystrophin-associated glycoprotein complex [GO:0016010]; plasma membrane [GO:0005886]; sarcoglycan complex [GO:0016012]; sarcolemma [GO:0042383]; sarcoplasmic reticulum [GO:0016529] 0.83465 0.19081 SIETPNVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8577 0 0 0 0 0 0 0 0 0 0 Q92630 DYRK2_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1) DYRK2 Homo sapiens (Human) DNA damage response [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of glycogen biosynthetic process [GO:0045725]; protein phosphorylation [GO:0006468]; regulation of signal transduction by p53 class mediator [GO:1901796]; smoothened signaling pathway [GO:0007224] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; ubiquitin ligase complex [GO:0000151] ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein tyrosine kinase activity [GO:0004713] 0.91318 -0.75644 AYDHKVHQHVALK 0 0 0 9.26329 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92636 FAN_HUMAN Protein FAN (Factor associated with neutral sphingomyelinase activation) (Factor associated with N-SMase activation) NSMAF FAN Homo sapiens (Human) ceramide metabolic process [GO:0006672]; positive regulation of apoptotic process [GO:0043065]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829] sphingomyelin phosphodiesterase activator activity [GO:0016230] 0.9157 -0.77623 EAVTGITVSR 0 0 0 0 0 0 0 0 0 9.34921 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92637 FCGRB_HUMAN Putative high affinity immunoglobulin gamma Fc receptor IB (IgG Fc receptor IB) (Fc gamma receptor IB pseudogene) (Fc-gamma RIB) (FcRIB) (hFcgammaRIB) FCGR1BP FCGR1B IGFRB Homo sapiens (Human) adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; immune response [GO:0006955]; regulation of immune response [GO:0050776] clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; plasma membrane [GO:0005886] IgG binding [GO:0019864]; immunoglobulin receptor activity [GO:0019763]; transmembrane signaling receptor activity [GO:0004888] 0.88161 -0.30558 CQEQKEEQLQEGVHR 0 0 0 0 0 0 0 0 0 0 11.7346 0 0 0 0 0 9.22062 0 0 0 0 0 0 0 0 0 0 Q92643 GPI8_HUMAN GPI-anchor transamidase (GPI transamidase) (EC 3.-.-.-) (GPI8 homolog) (hGPI8) (Phosphatidylinositol-glycan biosynthesis class K protein) (PIG-K) PIGK GPI8 Homo sapiens (Human) attachment of GPI anchor to protein [GO:0016255]; proteolysis [GO:0006508] endoplasmic reticulum membrane [GO:0005789]; GPI-anchor transamidase complex [GO:0042765]; membrane [GO:0016020] GPI-anchor transamidase activity [GO:0003923]; protein disulfide isomerase activity [GO:0003756] 0.80077 0.23936 SYEVTVENFLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.94037 Q92665 RT31_HUMAN "Small ribosomal subunit protein mS31 (28S ribosomal protein S31, mitochondrial) (MRP-S31) (S31mt) (Imogen 38)" MRPS31 IMOGN38 Homo sapiens (Human) mitochondrial translation [GO:0032543] mitochondrial inner membrane [GO:0005743]; mitochondrial small ribosomal subunit [GO:0005763]; mitochondrion [GO:0005739]; nucleolus [GO:0005730] protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.95823 -1.6866 ETSESQDSEK 0 0 0 0 8.94219 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2182 0 Q92667 AKAP1_HUMAN "A-kinase anchor protein 1, mitochondrial (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Protein kinase A-anchoring protein 1) (PRKA1) (Spermatid A-kinase anchor protein 84) (S-AKAP84)" AKAP1 AKAP149 PRKA1 Homo sapiens (Human) antiviral innate immune response [GO:0140374]; apoptotic process [GO:0006915] cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739] protein kinase A regulatory subunit binding [GO:0034237]; RNA binding [GO:0003723] 0.89725 -0.53064 DDSTKLELALTGGEAK 12.4257 0 0 0 0 0 0 0 0 0 0 0 0 10.3029 0 10.1163 0 0 0 12.6121 0 0 0 0 0 0 0 Q92670 ZN75C_HUMAN Putative zinc finger protein 75C (Zinc finger protein 75C pseudogene) ZNF75CP ZNF75C Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.88467 -0.29547 LTTCKQELPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0865 0 9.92303 0 0 0 Q92673 SORL_HUMAN Sortilin-related receptor (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) SORL1 C11orf32 Homo sapiens (Human) adaptive thermogenesis [GO:1990845]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; diet induced thermogenesis [GO:0002024]; endosome to plasma membrane protein transport [GO:0099638]; insulin receptor recycling [GO:0038020]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902960]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; negative regulation of neurofibrillary tangle assembly [GO:1902997]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron death [GO:1901215]; negative regulation of protein binding [GO:0032091]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of triglyceride catabolic process [GO:0010897]; neuropeptide signaling pathway [GO:0007218]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of choline O-acetyltransferase activity [GO:1902771]; positive regulation of early endosome to recycling endosome transport [GO:1902955]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; positive regulation of glial cell-derived neurotrophic factor production [GO:1900168]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein exit from endoplasmic reticulum [GO:0070863]; positive regulation of protein localization to early endosome [GO:1902966]; post-Golgi vesicle-mediated transport [GO:0006892]; protein localization to Golgi apparatus [GO:0034067]; protein maturation [GO:0051604]; protein retention in Golgi apparatus [GO:0045053]; protein targeting [GO:0006605]; protein targeting to lysosome [GO:0006622]; receptor-mediated endocytosis [GO:0006898]; regulation of smooth muscle cell migration [GO:0014910] cell surface [GO:0009986]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; multivesicular body [GO:0005771]; multivesicular body membrane [GO:0032585]; neuronal cell body [GO:0043025]; nuclear envelope lumen [GO:0005641]; perinucleolar compartment [GO:0097356]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658] amyloid-beta binding [GO:0001540]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor activity [GO:0005041]; neuropeptide binding [GO:0042923]; small GTPase binding [GO:0031267]; transmembrane signaling receptor activity [GO:0004888] 0.92756 -1.2249 CSSGTCVMDTWVCDGYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0161 0 0 0 Q92674 CENPI_HUMAN Centromere protein I (CENP-I) (FSH primary response protein 1) (Follicle-stimulating hormone primary response protein) (Interphase centromere complex protein 19) (Leucine-rich primary response protein 1) CENPI FSHPRH1 ICEN19 LRPR1 Homo sapiens (Human) CENP-A containing chromatin assembly [GO:0034080]; mitotic sister chromatid segregation [GO:0000070]; sex differentiation [GO:0007548] cytosol [GO:0005829]; inner kinetochore [GO:0000939]; kinetochore [GO:0000776]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654] 0.56581 0.49274 TGVAEYK 10.8104 11.0061 10.8828 0 0 9.73079 11.1163 0 0 8.9326 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92681 RSCA1_HUMAN Regulatory solute carrier protein family 1 member 1 (Transporter regulator RS1) (hRS1) RSC1A1 Homo sapiens (Human) negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; negative regulation of nucleoside transport [GO:0032243]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of transport [GO:0051051] cell junction [GO:0030054]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] sodium channel inhibitor activity [GO:0019871] 0.55929 0.54249 ASAEFQLNSEK 0 0 0 0 0 0 0 0 9.28707 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2068 0 0 0 Q92685 ALG3_HUMAN "Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase (EC 2.4.1.258) (Asparagine-linked glycosylation protein 3 homolog) (Dol-P-Man-dependent alpha(1-3)-mannosyltransferase) (Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase) (Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase) (Not56-like protein)" ALG3 NOT NOT56L Homo sapiens (Human) dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; protein glycosylation [GO:0006486] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789] "alpha-1,3-mannosyltransferase activity [GO:0000033]; dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity [GO:0052925]" 0.87706 0.0002107 VAYTEIDWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.6319 0 0 0 0 0 0 9.24436 0 0 0 0 Q92692 NECT2_HUMAN Nectin-2 (Herpes virus entry mediator B) (Herpesvirus entry mediator B) (HveB) (Nectin cell adhesion molecule 2) (Poliovirus receptor-related protein 2) (CD antigen CD112) NECTIN2 HVEB PRR2 PVRL2 Homo sapiens (Human) acrosome assembly [GO:0001675]; adhesion of symbiont to host [GO:0044406]; cell part morphogenesis [GO:0032990]; cilium organization [GO:0044782]; coreceptor-mediated virion attachment to host cell [GO:0046814]; cytoskeleton organization [GO:0007010]; establishment of localization in cell [GO:0051649]; establishment of mitochondrion localization [GO:0051654]; fertilization [GO:0009566]; fusion of virus membrane with host plasma membrane [GO:0019064]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; positive regulation of immunoglobulin mediated immune response [GO:0002891]; positive regulation of mast cell activation [GO:0033005]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002860]; positive regulation of T cell receptor signaling pathway [GO:0050862]; regulation of viral entry into host cell [GO:0046596]; sperm mitochondrion organization [GO:0030382]; spermatid development [GO:0007286]; spermatid nucleus differentiation [GO:0007289]; susceptibility to natural killer cell mediated cytotoxicity [GO:0042271]; susceptibility to T cell mediated cytotoxicity [GO:0060370] apical junction complex [GO:0043296]; cell surface [GO:0009986]; cell-cell contact zone [GO:0044291]; cell-cell junction [GO:0005911]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; plasma membrane [GO:0005886]; zonula adherens [GO:0005915] cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; virus receptor activity [GO:0001618] 0.83526 0.19216 VQVLPEVR 0 0 9.75236 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92696 PGTA_HUMAN Geranylgeranyl transferase type-2 subunit alpha (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit alpha) (Rab geranyl-geranyltransferase subunit alpha) (Rab GG transferase alpha) (Rab GGTase alpha) (Rab geranylgeranyltransferase subunit alpha) RABGGTA Homo sapiens (Human) protein geranylgeranylation [GO:0018344]; protein modification process [GO:0036211]; visual perception [GO:0007601] cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; Rab-protein geranylgeranyltransferase complex [GO:0005968] Rab geranylgeranyltransferase activity [GO:0004663]; small GTPase binding [GO:0031267]; zinc ion binding [GO:0008270] 0.88381 -0.32619 AVDPMRATYLDDLR 0 0 0 0 0 0 0 0 0 0 0 0 0 8.80003 0 0 9.64081 0 0 0 9.49867 0 0 11.1474 0 0 0 Q92698 RAD54_HUMAN DNA repair and recombination protein RAD54-like (EC 3.6.4.12) (RAD54 homolog) (hHR54) (hRAD54) RAD54L RAD54A Homo sapiens (Human) chromosome organization [GO:0051276]; determination of adult lifespan [GO:0008340]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; double-strand break repair via synthesis-dependent strand annealing [GO:0045003]; meiotic cell cycle [GO:0051321]; reciprocal meiotic recombination [GO:0007131]; response to ionizing radiation [GO:0010212]; response to xenobiotic stimulus [GO:0009410] nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent chromatin remodeler activity [GO:0140658]; ATP-dependent DNA/DNA annealing activity [GO:0036310]; DNA translocase activity [GO:0015616]; helicase activity [GO:0004386]; metal ion binding [GO:0046872] 0.89412 -0.51507 ALGLKRAGVR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1495 9.68554 0 0 0 0 0 0 0 0 0 8.86016 0 0 Q92729 PTPRU_HUMAN Receptor-type tyrosine-protein phosphatase U (R-PTP-U) (EC 3.1.3.48) (Pancreatic carcinoma phosphatase 2) (PCP-2) (Protein-tyrosine phosphatase J) (PTP-J) (hPTP-J) (Protein-tyrosine phosphatase pi) (PTP pi) (Protein-tyrosine phosphatase receptor omicron) (PTP-RO) (Receptor-type protein-tyrosine phosphatase psi) (R-PTP-psi) PTPRU FMI PCP2 PTPRO Homo sapiens (Human) animal organ regeneration [GO:0031100]; cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; homotypic cell-cell adhesion [GO:0034109]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; protein dephosphorylation [GO:0006470]; protein localization to cell surface [GO:0034394]; response to glucocorticoid [GO:0051384]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] cell-cell junction [GO:0005911]; plasma membrane [GO:0005886] beta-catenin binding [GO:0008013]; protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001] 0.95936 -1.8784 EIEYRMAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6148 0 Q92731 ESR2_HUMAN Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2) ESR2 ESTRB NR3A2 Homo sapiens (Human) cell-cell signaling [GO:0007267]; cellular response to estradiol stimulus [GO:0071392]; cellular response to estrogen stimulus [GO:0071391]; intracellular estrogen receptor signaling pathway [GO:0030520]; negative regulation of cell growth [GO:0030308]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165] chromatin [GO:0000785]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; estrogen response element binding [GO:0034056]; nuclear estrogen receptor activity [GO:0030284]; nuclear receptor activity [GO:0004879]; nuclear steroid receptor activity [GO:0003707]; receptor antagonist activity [GO:0048019]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; steroid binding [GO:0005496]; zinc ion binding [GO:0008270]" 0.82576 0.21385 SSITGSECSPAEDSK 0 0 0 0 0 11.6749 0 0 0 0 0 0 10.9487 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92733 PRCC_HUMAN Proline-rich protein PRCC (Papillary renal cell carcinoma translocation-associated gene protein) PRCC TPRC Homo sapiens (Human) cell cycle [GO:0007049]; regulation of cell cycle [GO:0051726] nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.92001 -0.90506 GREEINFVEIK 0 13.59 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.39386 0 0 9.2148 10.4034 9.47202 0 0 0 Q92736 RYR2_HUMAN Ryanodine receptor 2 (RYR-2) (RyR2) (hRYR-2) (Cardiac muscle ryanodine receptor) (Cardiac muscle ryanodine receptor-calcium release channel) (Type 2 ryanodine receptor) RYR2 Homo sapiens (Human) calcium ion transport [GO:0006816]; calcium ion transport into cytosol [GO:0060402]; calcium-mediated signaling [GO:0019722]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cell communication by electrical coupling involved in cardiac conduction [GO:0086064]; cellular response to caffeine [GO:0071313]; cellular response to epinephrine stimulus [GO:0071872]; detection of calcium ion [GO:0005513]; embryonic heart tube morphogenesis [GO:0003143]; establishment of localization in cell [GO:0051649]; establishment of protein localization to endoplasmic reticulum [GO:0072599]; intracellular calcium ion homeostasis [GO:0006874]; left ventricular cardiac muscle tissue morphogenesis [GO:0003220]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of heart rate [GO:0010460]; positive regulation of sequestering of calcium ion [GO:0051284]; positive regulation of the force of heart contraction [GO:0098735]; Purkinje myocyte to ventricular cardiac muscle cell signaling [GO:0086029]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of AV node cell action potential [GO:0098904]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of heart rate [GO:0002027]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; release of sequestered calcium ion into cytosol [GO:0051209]; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0014808]; response to caffeine [GO:0031000]; response to hypoxia [GO:0001666]; response to muscle activity [GO:0014850]; response to muscle stretch [GO:0035994]; response to redox state [GO:0051775]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; striated muscle contraction [GO:0006941]; type B pancreatic cell apoptotic process [GO:0097050]; ventricular cardiac muscle cell action potential [GO:0086005] calcium channel complex [GO:0034704]; junctional sarcoplasmic reticulum membrane [GO:0014701]; membrane [GO:0016020]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; smooth endoplasmic reticulum [GO:0005790]; Z disc [GO:0030018] calcium channel activity [GO:0005262]; calcium ion binding [GO:0005509]; calcium-induced calcium release activity [GO:0048763]; calcium-release channel activity [GO:0015278]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase A regulatory subunit binding [GO:0034237]; protein self-association [GO:0043621]; ryanodine-sensitive calcium-release channel activity [GO:0005219]; suramin binding [GO:0043924]; transmembrane transporter binding [GO:0044325] 0.96889 -12.733 AAVSDQERKK 15.2089 0 0 12.0306 11.8834 0 0 0 0 12.063 14.1165 0 0 0 13.0764 0 0 0 0 0 0 0 0 10.2334 12.1487 11.3957 0 Q92738 US6NL_HUMAN USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN-tre) USP6NL KIAA0019 Homo sapiens (Human) "activation of GTPase activity [GO:0090630]; Golgi organization [GO:0007030]; plasma membrane to endosome transport [GO:0048227]; positive regulation of GTPase activity [GO:0043547]; regulation of Golgi organization [GO:1903358]; retrograde transport, plasma membrane to Golgi [GO:0035526]; virion assembly [GO:0019068]" cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588] GTPase activator activity [GO:0005096]; small GTPase binding [GO:0031267] 0.95425 -1.5264 FQEHHEKILNK 0 0 0 0 0 0 0 0 0 8.61324 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.63392 0 0 Q92743 HTRA1_HUMAN Serine protease HTRA1 (EC 3.4.21.-) (High-temperature requirement A serine peptidase 1) (L56) (Serine protease 11) HTRA1 HTRA PRSS11 Homo sapiens (Human) chorionic trophoblast cell differentiation [GO:0060718]; dentinogenesis [GO:0097187]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of defense response to virus [GO:0050687]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; placenta development [GO:0001890]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation [GO:0050679]; programmed cell death [GO:0012501]; proteolysis [GO:0006508] collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] growth factor binding [GO:0019838]; identical protein binding [GO:0042802]; molecular function activator activity [GO:0140677]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236] 0.95983 -1.8581 FLTESHDRQAKGK 0 0 8.66274 0 0 0 0 0 0 8.46267 0 9.55515 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92747 ARC1A_HUMAN Actin-related protein 2/3 complex subunit 1A (SOP2-like protein) ARPC1A SOP2L Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; Arp2/3 complex-mediated actin nucleation [GO:0034314] actin cytoskeleton [GO:0015629]; Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; muscle cell projection membrane [GO:0036195]; nucleus [GO:0005634]; site of double-strand break [GO:0035861] actin binding [GO:0003779]; actin filament binding [GO:0051015] 0.9627 -2.4435 AATFVKWSPLENK 0 0 0 0 8.53947 8.56434 0 0 0 0 0 10.3518 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92750 TAF4B_HUMAN Transcription initiation factor TFIID subunit 4B (Transcription initiation factor TFIID 105 kDa subunit) (TAF(II)105) (TAFII-105) (TAFII105) TAF4B TAF2C2 TAFII105 Homo sapiens (Human) mRNA transcription by RNA polymerase II [GO:0042789]; oogenesis [GO:0048477]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; protein phosphorylation [GO:0006468]; RNA polymerase II preinitiation complex assembly [GO:0051123]; spermatogenesis [GO:0007283]; transcription initiation at RNA polymerase II promoter [GO:0006367] cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor TFIID complex [GO:0005669] DNA binding [GO:0003677]; NF-kappaB binding [GO:0051059]; protein heterodimerization activity [GO:0046982]; RNA polymerase II general transcription initiation factor activity [GO:0016251] 0.80791 0.22895 IEAEEFTRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3891 11.6826 0 0 0 11.3514 9.52154 0 11.2011 0 0 0 Q92752 TENR_HUMAN Tenascin-R (TN-R) (Janusin) (Restrictin) TNR Homo sapiens (Human) "associative learning [GO:0008306]; axon extension involved in regeneration [GO:0048677]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198]; locomotory exploration behavior [GO:0035641]; long-term synaptic potentiation [GO:0060291]; negative regulation of axon extension involved in regeneration [GO:0048692]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic transmission [GO:0050805]; neuroblast migration [GO:0097402]; neuromuscular process controlling balance [GO:0050885]; neuron cell-cell adhesion [GO:0007158]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transmission of nerve impulse [GO:0051971]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; synapse organization [GO:0050808]; synaptic transmission, glutamatergic [GO:0035249]; telencephalon cell migration [GO:0022029]" cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; membrane raft [GO:0045121]; perineuronal net [GO:0072534]; Schaffer collateral - CA1 synapse [GO:0098685]; tenascin complex [GO:0090733] 0.88591 -0.29357 ITSQGRYELR 0 0 0 0 0 0 0 0 0 0 0 0 9.54865 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92759 TF2H4_HUMAN General transcription factor IIH subunit 4 (Basic transcription factor 2 52 kDa subunit) (BTF2 p52) (General transcription factor IIH polypeptide 4) (TFIIH basal transcription factor complex p52 subunit) GTF2H4 Homo sapiens (Human) DNA repair [GO:0006281]; nucleotide-excision repair [GO:0006289]; transcription by RNA polymerase II [GO:0006366] core TFIIH complex portion of holo TFIIH complex [GO:0000438]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIH core complex [GO:0000439]; transcription factor TFIIH holo complex [GO:0005675] ATPase activator activity [GO:0001671]; double-stranded DNA binding [GO:0003690]; RNA polymerase II general transcription initiation factor activity [GO:0016251] 0.80263 0.24025 ELGVLVFENSAK 0 0 0 0 0 0 0 0 0 0 0 9.14374 9.52525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92764 KRT35_HUMAN "Keratin, type I cuticular Ha5 (Hair keratin, type I Ha5) (Keratin-35) (K35)" KRT35 HHA5 HKA5 KRTHA5 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; epithelial cell differentiation [GO:0030855]; intermediate filament organization [GO:0045109] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intermediate filament [GO:0005882] structural molecule activity [GO:0005198] 0.79879 0.23965 LAADDFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4739 0 0 0 0 0 0 0 0 Q92766 RREB1_HUMAN Ras-responsive element-binding protein 1 (RREB-1) (Finger protein in nuclear bodies) (Raf-responsive zinc finger protein LZ321) (Zinc finger motif enhancer-binding protein 1) (Zep-1) RREB1 FINB Homo sapiens (Human) "negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of mammary gland epithelial cell proliferation [GO:0033601]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing, spreading of epidermal cells [GO:1903691]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366]" cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; nuclear body [GO:0016604]; nuclear speck [GO:0016607]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.87383 0.025586 ADEVFHCPVCFK 12.7331 12.4909 12.5097 10.1924 10.3407 10.4131 11.9142 12.2201 12.2864 12.4113 12.4471 12.5199 0 10.9572 10.1582 11.8326 12.1136 11.6335 0 8.13253 0 0 0 0 8.71287 0 0 Q92769 HDAC2_HUMAN Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-) HDAC2 Homo sapiens (Human) behavioral response to ethanol [GO:0048149]; cardiac muscle hypertrophy [GO:0003300]; cellular response to dopamine [GO:1903351]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; chromatin remodeling [GO:0006338]; circadian regulation of gene expression [GO:0032922]; dendrite development [GO:0016358]; embryonic digit morphogenesis [GO:0042733]; epidermal cell differentiation [GO:0009913]; eyelid development in camera-type eye [GO:0061029]; fungiform papilla formation [GO:0061198]; hair follicle placode formation [GO:0060789]; heterochromatin organization [GO:0070828]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell migration [GO:0030336]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of neuron projection development [GO:0010977]; negative regulation of peptidyl-lysine acetylation [GO:2000757]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of male mating behavior [GO:1902437]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of proteolysis [GO:0045862]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell fate specification [GO:0042659]; regulation of stem cell differentiation [GO:2000736]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amphetamine [GO:0001975]; response to caffeine [GO:0031000]; response to cocaine [GO:0042220]; response to hyperoxia [GO:0055093]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to xenobiotic stimulus [GO:0009410] "chromatin [GO:0000785]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; ESC/E(Z) complex [GO:0035098]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NuRD complex [GO:0016581]; protein-containing complex [GO:0032991]; Sin3 complex [GO:0016580]" chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; histone deacetylase activity [GO:0004407]; histone deacetylase binding [GO:0042826]; histone decrotonylase activity [GO:0160009]; NF-kappaB binding [GO:0051059]; promoter-specific chromatin binding [GO:1990841]; protein de-2-hydroxyisobutyrylase activity [GO:0160010]; protein lysine deacetylase activity [GO:0033558]; RNA binding [GO:0003723]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific DNA binding [GO:0043565] 0.92455 -0.99048 ATAEEMTKYHSDEYIK 11.4496 0 0 0 0 0 0 0 0 11.9135 9.40661 12.0404 0 0 0 0 10.3344 0 0 0 0 0 0 0 0 0 0 Q92771 DDX12_HUMAN Putative ATP-dependent RNA helicase DDX12 (EC 3.6.4.13) (CHL1-related protein 2) (hCHLR2) (DEAD/H box protein 12) DDX12P CHLR2 DDX12 Homo sapiens (Human) DNA duplex unwinding [GO:0032508]; establishment of sister chromatid cohesion [GO:0034085]; nucleobase-containing compound metabolic process [GO:0006139] nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.96281 -2.6635 DLVNRLKAEQAR 13.3106 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.43756 0 0 0 0 0 0 0 0 0 0 0 Q92772 CDKL2_HUMAN Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein kinase KKIAMRE) CDKL2 Homo sapiens (Human) protein phosphorylation [GO:0006468]; sex differentiation [GO:0007548]; signal transduction [GO:0007165] centrosome [GO:0005813]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310] 0.88278 -0.06105 RPFCAELLHHDFFQMDGFAER 9.32389 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92781 RDH5_HUMAN Retinol dehydrogenase 5 (EC 1.1.1.209) (EC 1.1.1.315) (EC 1.1.1.53) (11-cis retinol dehydrogenase) (11-cis RDH) (11-cis RoDH) (9-cis retinol dehydrogenase) (9cRDH) (Short chain dehydrogenase/reductase family 9C member 5) RDH5 HSD17B9 RDH1 SDR9C5 Homo sapiens (Human) response to stimulus [GO:0050896]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202]; visual perception [GO:0007601] cell body [GO:0044297]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231] "11-cis-retinol dehydrogenase [GO:0106429]; androstan-3-alpha,17-beta-diol dehydrogenase activity [GO:0047044]; androsterone dehydrogenase activity [GO:0047023]; NAD-retinol dehydrogenase activity [GO:0004745]; protein homodimerization activity [GO:0042803]" 0.56062 0.52964 TLQACWAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.32749 0 0 0 0 9.38974 0 0 0 0 9.31687 9.24779 9.21791 Q92782 DPF1_HUMAN "Zinc finger protein neuro-d4 (BRG1-associated factor 45B) (BAF45B) (D4, zinc and double PHD fingers family 1)" DPF1 BAF45B NEUD4 Homo sapiens (Human) apoptotic process [GO:0006915]; chromatin remodeling [GO:0006338]; nervous system development [GO:0007399]; positive regulation of cell differentiation [GO:0045597]; positive regulation of double-strand break repair [GO:2000781]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nBAF complex [GO:0071565] metal ion binding [GO:0046872]; sequence-specific double-stranded DNA binding [GO:1990837] 0.9529 -1.4912 AYGIGGLR 0 0 0 0 0 0 0 0 0 10.9568 0 0 0 0 0 0 0 0 9.41397 0 0 0 0 0 0 0 0 Q92783 STAM1_HUMAN Signal transducing adapter molecule 1 (STAM-1) STAM STAM1 Homo sapiens (Human) macroautophagy [GO:0016236]; membrane fission [GO:0090148]; multivesicular body assembly [GO:0036258]; positive regulation of exosomal secretion [GO:1903543]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; regulation of extracellular exosome assembly [GO:1903551]; signal transduction [GO:0007165] cytosol [GO:0005829]; early endosome membrane [GO:0031901]; ESCRT-0 complex [GO:0033565]; intracellular membrane-bounded organelle [GO:0043231] phosphatidylinositol binding [GO:0035091]; ubiquitin binding [GO:0043130]; ubiquitin-like protein ligase binding [GO:0044389] 0.95469 -1.504 VGQSRTGPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.79074 0 0 0 0 0 0 0 0 0 0 0 0 Q92794 KAT6A_HUMAN "Histone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger protein) (Runt-related transcription factor-binding protein 2) (Zinc finger protein 220)" KAT6A MOZ MYST3 RUNXBP2 ZNF220 Homo sapiens (Human) cellular senescence [GO:0090398]; chromosome organization [GO:0051276]; histone acetylation [GO:0016573]; myeloid cell differentiation [GO:0030099]; negative regulation of DNA-templated transcription [GO:0045892]; nucleosome assembly [GO:0006334]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; protein acetylation [GO:0006473]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355]; regulation of hemopoiesis [GO:1903706]; regulation of signal transduction by p53 class mediator [GO:1901796] cytosol [GO:0005829]; MOZ/MORF histone acetyltransferase complex [GO:0070776]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; PML body [GO:0016605] acetyltransferase activity [GO:0016407]; DNA binding [GO:0003677]; DNA-binding transcription factor binding [GO:0140297]; histone acetyltransferase activity [GO:0004402]; histone H3K14 acetyltransferase activity [GO:0036408]; histone H4K12 acetyltransferase activity [GO:0043997]; histone H4K16 acetyltransferase activity [GO:0046972]; histone H4K5 acetyltransferase activity [GO:0043995]; histone H4K8 acetyltransferase activity [GO:0043996]; transcription coactivator activity [GO:0003713]; zinc ion binding [GO:0008270] 0.89693 -0.5315 CGWFHPPANEIYRK 0 0 0 0 0 9.23213 0 0 0 0 9.49105 0 0 10.5158 0 0 10.1473 0 0 0 0 0 9.33447 0 0 0 0 Q92800 EZH1_HUMAN Histone-lysine N-methyltransferase EZH1 (EC 2.1.1.356) (ENX-2) (Enhancer of zeste homolog 1) EZH1 KIAA0388 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; chromatin remodeling [GO:0006338]; heterochromatin formation [GO:0031507]; hippocampus development [GO:0021766]; histone H3-K27 trimethylation [GO:0098532]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; subtelomeric heterochromatin formation [GO:0031509] "chromosome, telomeric region [GO:0000781]; ESC/E(Z) complex [GO:0035098]; heterochromatin [GO:0000792]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]" chromatin binding [GO:0003682]; histone H3K27 methyltransferase activity [GO:0046976]; histone H3K27 trimethyltransferase activity [GO:0140951]; transcription corepressor activity [GO:0003714] 0.96525 -2.3769 CQTPTKQK 0 0 0 0 0 11.3373 0 0 0 0 0 10.1459 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92805 GOGA1_HUMAN Golgin subfamily A member 1 (Golgin-97) GOLGA1 Homo sapiens (Human) acrosomal vesicle [GO:0001669]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; perinuclear region of cytoplasm [GO:0048471]; trans-Golgi network [GO:0005802] 0.72619 0.34769 EINFEYLK 0 0 0 0 0 0 0 10.0819 10.1033 0 0 0 0 0 0 0 9.89949 0 0 9.58045 0 0 9.47033 0 0 0 0 Q92813 IOD2_HUMAN Type II iodothyronine deiodinase (EC 1.21.99.4) (5DII) (DIOII) (Type 2 DI) (Type-II 5'-deiodinase) DIO2 ITDI2 TXDI2 Homo sapiens (Human) brown fat cell differentiation [GO:0050873]; cellular lipid metabolic process [GO:0044255]; hormone biosynthetic process [GO:0042446]; positive regulation of cold-induced thermogenesis [GO:0120162]; selenocysteine incorporation [GO:0001514]; thyroid hormone catabolic process [GO:0042404]; thyroid hormone generation [GO:0006590]; thyroid hormone metabolic process [GO:0042403] membrane [GO:0016020]; plasma membrane [GO:0005886] selenium binding [GO:0008430]; thyroxine 5'-deiodinase activity [GO:0004800]; thyroxine 5-deiodinase activity [GO:0033798]; ubiquitin protein ligase binding [GO:0031625] 0.84358 0.15231 IAYLGGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5843 0 0 0 0 0 0 0 0 0 0 Q92817 EVPL_HUMAN Envoplakin (210 kDa cornified envelope precursor protein) (210 kDa paraneoplastic pemphigus antigen) (p210) EVPL Homo sapiens (Human) epidermis development [GO:0008544]; intermediate filament cytoskeleton organization [GO:0045104]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; regulation of antibacterial peptide production [GO:0002786]; wound healing [GO:0042060] cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; desmosome [GO:0030057]; extracellular exosome [GO:0070062]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020] cadherin binding [GO:0045296]; structural molecule activity [GO:0005198] 0.9689 -5.7797 ARDQADQECGR 0 0 0 0 0 0 0 0 0 0 0 0 13.486 0 0 0 0 0 8.81221 0 0 0 10.1416 0 0 9.13883 0 Q92819 HYAS2_HUMAN Hyaluronan synthase 2 (EC 2.4.1.212) (Hyaluronate synthase 2) (Hyaluronic acid synthase 2) (HA synthase 2) HAS2 Homo sapiens (Human) atrioventricular canal development [GO:0036302]; bone morphogenesis [GO:0060349]; cellular response to fluid shear stress [GO:0071498]; cellular response to interleukin-1 [GO:0071347]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to tumor necrosis factor [GO:0071356]; endocardial cushion to mesenchymal transition [GO:0090500]; estrous cycle [GO:0044849]; extracellular matrix assembly [GO:0085029]; extracellular polysaccharide biosynthetic process [GO:0045226]; hyaluronan biosynthetic process [GO:0030213]; kidney development [GO:0001822]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of urine volume [GO:0035810]; regulation of extracellular matrix assembly [GO:1901201]; renal water absorption [GO:0070295]; vasculogenesis [GO:0001570] cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum membrane [GO:0005789]; extracellular vesicle [GO:1903561]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; lysosome [GO:0005764]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853] hyaluronan synthase activity [GO:0050501]; identical protein binding [GO:0042802] 0.96904 -3.3761 SLETPIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.39137 0 0 0 Q92820 GGH_HUMAN Gamma-glutamyl hydrolase (EC 3.4.19.9) (Conjugase) (GH) (Gamma-Glu-X carboxypeptidase) GGH Homo sapiens (Human) tetrahydrofolylpolyglutamate metabolic process [GO:0046900] azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; melanosome [GO:0042470]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; vacuole [GO:0005773] exopeptidase activity [GO:0008238]; gamma-glutamyl-peptidase activity [GO:0034722]; omega peptidase activity [GO:0008242] 0.75423 0.30826 YYIAASYVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0189 0 0 0 9.5924 0 0 0 Q92823 NRCAM_HUMAN Neuronal cell adhesion molecule (Nr-CAM) (Neuronal surface protein Bravo) (hBravo) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) NRCAM KIAA0343 Homo sapiens (Human) angiogenesis [GO:0001525]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; axonogenesis [GO:0007409]; brain development [GO:0007420]; cell-cell adhesion [GO:0098609]; central nervous system development [GO:0007417]; clustering of voltage-gated sodium channels [GO:0045162]; neuron migration [GO:0001764]; neuronal action potential propagation [GO:0019227]; positive regulation of neuron differentiation [GO:0045666]; protein localization [GO:0008104]; regulation of axon extension [GO:0030516]; regulation of neuron projection development [GO:0010975]; regulation of postsynapse organization [GO:0099175]; retinal ganglion cell axon guidance [GO:0031290]; synapse assembly [GO:0007416] axon [GO:0030424]; axon initial segment [GO:0043194]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; glutamatergic synapse [GO:0098978]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839] ankyrin binding [GO:0030506]; cell-cell adhesion mediator activity [GO:0098632]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080] 0.96938 -5.5706 GHLQGYRIYYWK 0 0 0 0 0 0 0 0 0 0 0 9.15289 0 0 9.59343 0 0 0 0 0 9.12933 0 0 0 0 0 0 Q92826 HXB13_HUMAN Homeobox protein Hox-B13 HOXB13 Homo sapiens (Human) angiogenesis [GO:0001525]; epidermis development [GO:0008544]; epithelial cell maturation involved in prostate gland development [GO:0060743]; negative regulation of transcription by RNA polymerase II [GO:0000122]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; regulation of growth [GO:0040008]; regulation of transcription by RNA polymerase II [GO:0006357]; response to testosterone [GO:0033574]; response to wounding [GO:0009611] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; transcription regulator complex [GO:0005667] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; methyl-CpG binding [GO:0008327]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.87355 0.03527 ISAATSLSER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.05 0 Q92828 COR2A_HUMAN Coronin-2A (IR10) (WD repeat-containing protein 2) CORO2A IR10 WDR2 Homo sapiens (Human) intracellular signal transduction [GO:0035556] transcription repressor complex [GO:0017053] actin filament binding [GO:0051015] 0.88839 -0.43571 GLDVSSCEIFR 0 8.99822 0 0 0 0 0 0 0 9.20697 0 9.08881 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92832 NELL1_HUMAN Protein kinase C-binding protein NELL1 (NEL-like protein 1) (Nel-related protein 1) NELL1 NRP1 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of protein catabolic process [GO:0042177]; nervous system development [GO:0007399]; positive regulation of bone mineralization [GO:0030501]; positive regulation of ossification [GO:0045778]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of gene expression [GO:0010468]; regulation of osteoblast differentiation [GO:0045667] cytoplasm [GO:0005737]; extracellular space [GO:0005615]; nuclear envelope [GO:0005635]; perinuclear region of cytoplasm [GO:0048471] calcium ion binding [GO:0005509]; heparin binding [GO:0008201] 0.95583 -1.5886 ILTKSCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.37689 0 0 0 Q92833 JARD2_HUMAN Protein Jumonji (Jumonji/ARID domain-containing protein 2) JARID2 JMJ Homo sapiens (Human) cardiac muscle cell proliferation [GO:0060038]; cellular response to leukemia inhibitory factor [GO:1990830]; central nervous system development [GO:0007417]; chromatin remodeling [GO:0006338]; dosage compensation by inactivation of X chromosome [GO:0009048]; facultative heterochromatin formation [GO:0140718]; liver development [GO:0001889]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein localization to pericentric heterochromatin [GO:1902682]; spleen development [GO:0048536]; stem cell differentiation [GO:0048863]; thymus development [GO:0048538] ESC/E(Z) complex [GO:0035098]; histone methyltransferase complex [GO:0035097]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; histone demethylase activity [GO:0032452]; histone H3K27 methyltransferase activity [GO:0046976]; ubiquitin binding [GO:0043130]; ubiquitin modification-dependent histone binding [GO:0061649] 0.91546 -0.834 APAERGLLNGHVKK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5803 0 10.0362 0 0 0 0 0 10.5587 10.5379 0 0 10.517 0 Q92834 RPGR_HUMAN X-linked retinitis pigmentosa GTPase regulator RPGR RP3 XLRP3 Homo sapiens (Human) cilium assembly [GO:0060271]; intracellular protein transport [GO:0006886]; intraciliary transport [GO:0042073]; protein ubiquitination [GO:0016567]; response to stimulus [GO:0050896]; ubiquitin-dependent protein catabolic process [GO:0006511]; visual perception [GO:0007601] centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; photoreceptor outer segment [GO:0001750]; sperm flagellum [GO:0036126] guanyl-nucleotide exchange factor activity [GO:0005085]; RNA binding [GO:0003723]; ubiquitin protein ligase activity [GO:0061630] 0.96739 -2.8117 IFLFKRVPSINQK 0 0 0 0 0 0 0 9.31933 10.2664 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92835 SHIP1_HUMAN "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (EC 3.1.3.86) (Inositol polyphosphate-5-phosphatase D) (EC 3.1.3.56) (Inositol polyphosphate-5-phosphatase of 145 kDa) (SIP-145) (Phosphatidylinositol 4,5-bisphosphate 5-phosphatase) (EC 3.1.3.36) (SH2 domain-containing inositol 5'-phosphatase 1) (SH2 domain-containing inositol phosphatase 1) (SHIP-1) (p150Ship) (hp51CN)" INPP5D SHIP SHIP1 Homo sapiens (Human) apoptotic process [GO:0006915]; determination of adult lifespan [GO:0008340]; immunoglobulin mediated immune response [GO:0016064]; intracellular signal transduction [GO:0035556]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of bone resorption [GO:0045779]; negative regulation of immune response [GO:0050777]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of neutrophil differentiation [GO:0045659]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of signal transduction [GO:0009968]; phosphate-containing compound metabolic process [GO:0006796]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852] cytoskeleton [GO:0005856]; cytosol [GO:0005829]; membrane raft [GO:0045121]; plasma membrane [GO:0005886] "inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity [GO:0052659]; inositol-1,4,5-trisphosphate 5-phosphatase activity [GO:0052658]; inositol-polyphosphate 5-phosphatase activity [GO:0004445]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity [GO:0034485]; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity [GO:0004439]; SH3 domain binding [GO:0017124]" 0.95905 -1.7135 EKLYDFVK 8.70867 0 0 0 0 0 0 0 0 0 0 10.3725 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92838 EDA_HUMAN "Ectodysplasin-A (Ectodermal dysplasia protein) (EDA protein) [Cleaved into: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form]" EDA ED1 EDA2 Homo sapiens (Human) animal organ development [GO:0048513]; canonical Wnt signaling pathway [GO:0060070]; cell differentiation [GO:0030154]; cell-matrix adhesion [GO:0007160]; cytokine-mediated signaling pathway [GO:0019221]; gene expression [GO:0010467]; hair follicle placode formation [GO:0060789]; immune response [GO:0006955]; odontogenesis of dentin-containing tooth [GO:0042475]; pigmentation [GO:0043473]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of NIK/NF-kappaB signaling [GO:1901222]; salivary gland cavitation [GO:0060662]; trachea gland development [GO:0061153] apical part of cell [GO:0045177]; collagen trimer [GO:0005581]; cytoskeleton [GO:0005856]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; plasma membrane [GO:0005886] death receptor agonist activity [GO:0038177]; death receptor binding [GO:0005123]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164] 0.67746 0.39371 LGEAPAS 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.45734 0 0 0 0 11.2193 0 Q92839 HYAS1_HUMAN Hyaluronan synthase 1 (EC 2.4.1.212) (Hyaluronate synthase 1) (Hyaluronic acid synthase 1) (HA synthase 1) (HuHAS1) HAS1 HAS Homo sapiens (Human) cell adhesion [GO:0007155]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; extracellular matrix assembly [GO:0085029]; extracellular polysaccharide biosynthetic process [GO:0045226]; glycosaminoglycan biosynthetic process [GO:0006024]; hyaluronan biosynthetic process [GO:0030213]; negative regulation of fibroblast migration [GO:0010764] Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886] hyaluronan synthase activity [GO:0050501]; identical protein binding [GO:0042802] 0.7602 0.29369 HLTNRMLSMGYATK 0 0 0 12.3686 0 0 0 0 0 0 0 0 0 0 0 0 0 8.90545 0 0 0 0 0 0 0 0 0 Q92841 DDX17_HUMAN Probable ATP-dependent RNA helicase DDX17 (EC 3.6.4.13) (DEAD box protein 17) (DEAD box protein p72) (DEAD box protein p82) (RNA-dependent helicase p72) DDX17 Homo sapiens (Human) "alternative mRNA splicing, via spliceosome [GO:0000380]; androgen receptor signaling pathway [GO:0030521]; defense response to virus [GO:0051607]; epithelial to mesenchymal transition [GO:0001837]; immune system process [GO:0002376]; intracellular estrogen receptor signaling pathway [GO:0030520]; miRNA metabolic process [GO:0010586]; myoblast differentiation [GO:0045445]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of skeletal muscle cell differentiation [GO:2001014]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA processing [GO:0006396]; RNA-mediated gene silencing [GO:0031047]; rRNA processing [GO:0006364]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] "ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent activity, acting on RNA [GO:0008186]; mRNA 3'-UTR binding [GO:0003730]; ribonucleoprotein complex binding [GO:0043021]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; transcription coactivator activity [GO:0003713]" 0 7.4935 APILIATDVASR 0 0 0 0 0 0 9.5647 9.47442 0 10.1017 9.26087 8.46842 9.62277 10.1005 10.0464 10.9916 10.6324 0 0 0 9.8099 0 0 0 11.11 11.7505 9.69646 Q92845 KIFA3_HUMAN Kinesin-associated protein 3 (KAP-3) (KAP3) (Smg GDS-associated protein) KIFAP3 KIF3AP SMAP Homo sapiens (Human) cardiac muscle cell apoptotic process [GO:0010659]; cilium organization [GO:0044782]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of thymocyte apoptotic process [GO:0070244]; neuroblast proliferation [GO:0007405]; plus-end-directed vesicle transport along microtubule [GO:0072383]; positive regulation of calcium-dependent cell-cell adhesion [GO:0046587]; protein localization [GO:0008104]; protein-containing complex assembly [GO:0065003]; signal transduction [GO:0007165]; thymocyte apoptotic process [GO:0070242] axoneme [GO:0005930]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary tip [GO:0097542]; ciliary transition zone [GO:0035869]; cilium [GO:0005929]; condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; kinesin II complex [GO:0016939]; microtubule cytoskeleton [GO:0015630]; periciliary membrane compartment [GO:1990075]; photoreceptor connecting cilium [GO:0032391]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750] intraciliary transport particle B binding [GO:0120170]; kinesin binding [GO:0019894]; protein phosphatase binding [GO:0019903] 0.91527 -0.80464 AVDEDPENQTLRKDYEK 0 9.8042 0 0 0 9.02251 0 0 0 0 0 0 0 0 10.0996 0 9.40846 0 0 0 0 0 0 0 0 0 8.46577 Q92859 NEO1_HUMAN Neogenin (Immunoglobulin superfamily DCC subclass member 2) NEO1 IGDCC2 NGN Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; multicellular organismal-level iron ion homeostasis [GO:0060586]; neuron migration [GO:0001764] axonal growth cone [GO:0044295]; cell surface [GO:0009986]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; plasma membrane protein complex [GO:0098797] co-receptor binding [GO:0039706] 0.89862 -0.5595 ITDSRYYTVR 0 0 0 0 0 0 0 0 0 9.51126 9.85435 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92871 PMM1_HUMAN Phosphomannomutase 1 (PMM 1) (EC 5.4.2.8) (PMMH-22) PMM1 PMMH22 Homo sapiens (Human) cellular response to leukemia inhibitory factor [GO:1990830]; GDP-mannose biosynthetic process [GO:0009298]; mannose metabolic process [GO:0006013]; protein N-linked glycosylation [GO:0006487] cytosol [GO:0005829]; neuronal cell body [GO:0043025] metal ion binding [GO:0046872]; phosphomannomutase activity [GO:0004615] 0.82952 0.20998 VQIGVVGGSDYCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.43686 0 0 0 0 0 0 Q92874 DNSL2_HUMAN Deoxyribonuclease-1-like 2 (EC 3.1.21.-) (DNase I homolog protein DHP1) (Deoxyribonuclease I-like 2) (DNase I-like 2) DNASE1L2 DHP1 DNAS1L2 Homo sapiens (Human) corneocyte development [GO:0003335]; DNA catabolic process [GO:0006308]; DNA metabolic process [GO:0006259]; hair follicle development [GO:0001942] cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634] calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA nuclease activity [GO:0004536]; endonuclease activity [GO:0004519] 0.86209 0.094741 DQYKEMYLFVYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.00689 0 0 0 0 0 0 0 0 0 0 0 Q92878 RAD50_HUMAN DNA repair protein RAD50 (hRAD50) (EC 3.6.-.-) RAD50 Homo sapiens (Human) chromosome organization involved in meiotic cell cycle [GO:0070192]; DNA damage response [GO:0006974]; DNA double-strand break processing [GO:0000729]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA strand resection involved in replication fork processing [GO:0110025]; double-strand break repair [GO:0006302]; homologous recombination [GO:0035825]; mitotic G2/M transition checkpoint [GO:0044818]; negative regulation of telomere capping [GO:1904354]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of kinase activity [GO:0033674]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of telomere maintenance [GO:0032206]; reciprocal meiotic recombination [GO:0007131]; regulation of mitotic recombination [GO:0000019]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722]; telomere maintenance via telomerase [GO:0007004]; telomeric 3' overhang formation [GO:0031860] "BRCA1-C complex [GO:0070533]; chromosomal region [GO:0098687]; chromosome, telomeric region [GO:0000781]; condensed nuclear chromosome [GO:0000794]; membrane [GO:0016020]; Mre11 complex [GO:0030870]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]" ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA binding [GO:0003677]; double-stranded telomeric DNA binding [GO:0003691]; G-quadruplex DNA binding [GO:0051880]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein-macromolecule adaptor activity [GO:0030674]; single-stranded telomeric DNA binding [GO:0043047] 0.96908 -7.5284 DQITSKEAQLTSSK 11.6811 0 0 0 0 0 0 0 0 0 0 0 0 11.7039 0 0 10.217 0 0 0 10.3914 10.5236 0 8.62815 0 12.2937 0 Q92879 CELF1_HUMAN CUGBP Elav-like family member 1 (CELF-1) (50 kDa nuclear polyadenylated RNA-binding protein) (Bruno-like protein 2) (CUG triplet repeat RNA-binding protein 1) (CUG-BP1) (CUG-BP- and ETR-3-like factor 1) (Deadenylation factor CUG-BP) (Embryo deadenylation element-binding protein homolog) (EDEN-BP homolog) (RNA-binding protein BRUNOL-2) CELF1 BRUNOL2 CUGBP CUGBP1 NAB50 Homo sapiens (Human) "embryo development ending in birth or egg hatching [GO:0009792]; germ cell development [GO:0007281]; mRNA destabilization [GO:0061157]; mRNA processing [GO:0006397]; mRNA splice site selection [GO:0006376]; ncRNA-mediated post-transcriptional gene silencing [GO:0035194]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; positive regulation of gene expression [GO:0010628]; post-transcriptional gene silencing [GO:0016441]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of inflammatory response [GO:0050727]; regulation of RNA splicing [GO:0043484]" cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinucleolar compartment [GO:0097356]; ribonucleoprotein complex [GO:1990904] BRE binding [GO:0042835]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; mRNA regulatory element binding translation repressor activity [GO:0000900]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723] 0.9135 -0.76217 MFVGQVPRTWSEK 0 0 0 0 0 0 0 0 0 12.0053 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92882 OSTF1_HUMAN Osteoclast-stimulating factor 1 OSTF1 Homo sapiens (Human) ossification [GO:0001503]; signal transduction [GO:0007165] extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774] SH3 domain binding [GO:0017124] 0.34094 0.77109 GARTDLR 0 0 0 0 0 0 0 0 0 0 0 0 11.001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92888 ARHG1_HUMAN Rho guanine nucleotide exchange factor 1 (115 kDa guanine nucleotide exchange factor) (p115-RhoGEF) (p115RhoGEF) (Sub1.5) ARHGEF1 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266] cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886] G protein-coupled receptor binding [GO:0001664]; GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; RNA binding [GO:0003723] 0.92287 -1.0564 AFLDFYHSFLEK 0 9.87857 0 0 0 0 0 10.0583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92896 GSLG1_HUMAN Golgi apparatus protein 1 (CFR-1) (Cysteine-rich fibroblast growth factor receptor) (E-selectin ligand 1) (ESL-1) (Golgi sialoglycoprotein MG-160) GLG1 CFR1 ESL1 MG160 Homo sapiens (Human) bone morphogenesis [GO:0060349]; negative regulation of protein processing [GO:0010955]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; protein processing [GO:0016485]; regulation of chondrocyte differentiation [GO:0032330]; transforming growth factor beta receptor signaling pathway [GO:0007179] cytoskeleton [GO:0005856]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; plasma membrane [GO:0005886] fibroblast growth factor binding [GO:0017134]; signaling receptor binding [GO:0005102] 0.88665 -0.36145 ERFCENTQAGEGRVYK 10.1788 12.3766 12.0591 9.66633 8.27566 0 11.8136 0 12.218 11.6872 11.9927 0 0 0 0 11.9132 11.9137 11.9572 0 0 0 0 0 0 0 0 0 Q92900 RENT1_HUMAN Regulator of nonsense transcripts 1 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog) (hUpf1) UPF1 KIAA0221 RENT1 Homo sapiens (Human) "3'-UTR-mediated mRNA destabilization [GO:0061158]; cell cycle phase transition [GO:0044770]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; DNA duplex unwinding [GO:0032508]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; histone mRNA catabolic process [GO:0071044]; mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of mRNA catabolic process [GO:0061014]; regulation of telomere maintenance [GO:0032204]; regulation of translational termination [GO:0006449]; telomere maintenance via semi-conservative replication [GO:0032201]" "chromatin [GO:0000785]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; exon-exon junction complex [GO:0035145]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; perinuclear region of cytoplasm [GO:0048471]; supraspliceosomal complex [GO:0044530]" ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; chromatin binding [GO:0003682]; double-stranded DNA helicase activity [GO:0036121]; helicase activity [GO:0004386]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; telomeric DNA binding [GO:0042162]; zinc ion binding [GO:0008270] 0.88337 -0.086936 AGLSQSLFER 0 0 10.9101 0 0 0 0 10.6562 0 0 10.9522 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3822 Q92904 DAZL_HUMAN Deleted in azoospermia-like (DAZ homolog) (DAZ-like autosomal) (Deleted in azoospermia-like 1) (SPGY-like-autosomal) DAZL DAZH DAZL1 DAZLA SPGYLA Homo sapiens (Human) 3'-UTR-mediated mRNA stabilization [GO:0070935]; germ cell development [GO:0007281]; positive regulation of translational initiation [GO:0045948]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; translation activator activity [GO:0008494] 0.91743 -0.8533 TGVSKGYGFVSFFNDVDVQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3422 Q92911 SC5A5_HUMAN Sodium/iodide cotransporter (Na(+)/I(-) cotransporter) (Natrium iodide transporter) (Sodium-iodide symporter) (Na(+)/I(-) symporter) (Solute carrier family 5 member 5) SLC5A5 NIS Homo sapiens (Human) cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to Thyroid stimulating hormone [GO:1904401]; iodide transmembrane transport [GO:1904200]; iodide transport [GO:0015705]; monoatomic ion transport [GO:0006811]; sodium ion transport [GO:0006814]; thyroid hormone generation [GO:0006590]; transport across blood-brain barrier [GO:0150104] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular vesicle [GO:1903561]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886] iodide transmembrane transporter activity [GO:0015111]; monoatomic anion:sodium symporter activity [GO:0015373]; protein homodimerization activity [GO:0042803]; sodium:iodide symporter activity [GO:0008507] 0.9589 -1.7161 YVACRTEK 9.39195 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92915 FGF14_HUMAN Fibroblast growth factor 14 (FGF-14) (Fibroblast growth factor homologous factor 4) (FHF-4) FGF14 FHF4 Homo sapiens (Human) cell-cell signaling [GO:0007267]; JNK cascade [GO:0007254]; nervous system development [GO:0007399]; regulation of voltage-gated sodium channel activity [GO:1905150]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; nucleus [GO:0005634] growth factor activity [GO:0008083]; heparin binding [GO:0008201] 0.95291 -1.4636 QDPQLKGIVTR 0 0 0 0 0 0 0 0 0 0 8.43659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92917 GPKOW_HUMAN G-patch domain and KOW motifs-containing protein (G-patch domain-containing protein 5) (Protein MOS2 homolog) (Protein T54) GPKOW GPATC5 GPATCH5 T54 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]" nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681] RNA binding [GO:0003723] 0.95954 -1.8161 RRLADSGDGAGPSPEEK 0 0 0 0 0 0 0 11.7214 0 0 8.59126 0 0 0 0 10.3846 0 0 0 0 0 0 0 0 0 0 0 Q92922 SMRC1_HUMAN SWI/SNF complex subunit SMARCC1 (BRG1-associated factor 155) (BAF155) (SWI/SNF complex 155 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1) SMARCC1 BAF155 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; chromatin remodeling [GO:0006338]; insulin receptor signaling pathway [GO:0008286]; negative regulation of cell differentiation [GO:0045596]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; nervous system development [GO:0007399]; nucleosome disassembly [GO:0006337]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357] brahma complex [GO:0035060]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; GBAF complex [GO:0140288]; kinetochore [GO:0000776]; male germ cell nucleus [GO:0001673]; nBAF complex [GO:0071565]; npBAF complex [GO:0071564]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; RSC-type complex [GO:0016586]; SWI/SNF complex [GO:0016514]; XY body [GO:0001741] chromatin binding [GO:0003682]; histone binding [GO:0042393]; transcription coactivator activity [GO:0003713] 0.94785 -1.3582 EWTEQETLLLLEALEMYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5687 0 0 0 0 0 9.71586 0 0 0 0 Q92935 EXTL1_HUMAN Exostosin-like 1 (EC 2.4.1.224) (Exostosin-L) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostosis-like protein) EXTL1 EXTL Homo sapiens (Human) heparan sulfate proteoglycan biosynthetic process [GO:0015012]; protein glycosylation [GO:0006486]; skeletal system development [GO:0001501] endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794] acetylglucosaminyltransferase activity [GO:0008375]; glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity [GO:0050508]; glucuronosyltransferase activity [GO:0015020] 0.90775 -0.73541 GRNHLVLRLHPAPCPR 11.0346 0 0 0 0 9.72306 0 10.5967 0 0 0 0 9.89459 0 0 10.3321 0 0 0 0 0 0 0 0 0 0 0 Q92945 FUBP2_HUMAN Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75) KHSRP FUBP2 Homo sapiens (Human) "3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to cytokine stimulus [GO:0071345]; miRNA metabolic process [GO:0010586]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; positive regulation of mRNA catabolic process [GO:0061014]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of mRNA stability [GO:0043488]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA binding [GO:0003729]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723] 0 7.2544 IGGGIDVPVPR 0 0 0 0 0 0 8.85543 0 0 9.07957 0 0 9.94033 8.43045 9.71254 0 11.4053 9.73711 0 0 8.43554 7.9888 8.04718 0 10.5563 11.0015 10.7564 Q92947 GCDH_HUMAN "Glutaryl-CoA dehydrogenase, mitochondrial (GCD) (EC 1.3.8.6)" GCDH Homo sapiens (Human) fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; fatty-acyl-CoA biosynthetic process [GO:0046949]; tryptophan metabolic process [GO:0006568] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] fatty-acyl-CoA binding [GO:0000062]; flavin adenine dinucleotide binding [GO:0050660]; glutaryl-CoA dehydrogenase activity [GO:0004361] 0.9543 -1.5223 TYCQERLMPR 0 0 0 0 0 0 9.48208 0 0 9.52793 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92954 PRG4_HUMAN Proteoglycan 4 (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Cleaved into: Proteoglycan 4 C-terminal part] PRG4 MSF SZP Homo sapiens (Human) immune response [GO:0006955] collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615] polysaccharide binding [GO:0030247]; scavenger receptor activity [GO:0005044] 0.93894 -1.32 KPTSTKKPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16.69 0 0 0 0 0 0 0 0 0 10.1167 9.64449 Q92963 RIT1_HUMAN GTP-binding protein Rit1 (EC 3.6.5.2) (Ras-like protein expressed in many tissues) (Ras-like without CAAX protein 1) RIT1 RIBB RIT ROC1 Homo sapiens (Human) Ras protein signal transduction [GO:0007265]; signal transduction [GO:0007165] plasma membrane [GO:0005886] calmodulin binding [GO:0005516]; G protein activity [GO:0003925]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.89015 -0.49201 LVMLGAGGVGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9009 0 0 0 0 0 0 Q92966 SNPC3_HUMAN snRNA-activating protein complex subunit 3 (SNAPc subunit 3) (Proximal sequence element-binding transcription factor subunit beta) (PSE-binding factor subunit beta) (PTF subunit beta) (Small nuclear RNA-activating complex polypeptide 3) (snRNA-activating protein complex 50 kDa subunit) (SNAPc 50 kDa subunit) SNAPC3 SNAP50 Homo sapiens (Human) snRNA transcription [GO:0009301]; snRNA transcription by RNA polymerase II [GO:0042795]; snRNA transcription by RNA polymerase III [GO:0042796]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383] nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; snRNA-activating protein complex [GO:0019185] bent DNA binding [GO:0003681]; DNA binding [GO:0003677]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III type 3 promoter sequence-specific DNA binding [GO:0001006] 0.72155 0.35929 DLSRTIIEWSESHDR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3864 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92973 TNPO1_HUMAN Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP) TNPO1 KPNB2 MIP1 TRN Homo sapiens (Human) protein import into nucleus [GO:0006606] cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634] nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; RNA binding [GO:0003723]; small GTPase binding [GO:0031267] 0.88489 -0.28823 FLQFFKHSSPK 0 0 0 0 0 0 9.30973 13.3753 0 0 0 0 0 0 0 0 0 0 0 0 9.39941 0 0 0 0 0 0 Q92974 ARHG2_HUMAN Rho guanine nucleotide exchange factor 2 (Guanine nucleotide exchange factor H1) (GEF-H1) (Microtubule-regulated Rho-GEF) (Proliferating cell nucleolar antigen p40) ARHGEF2 KIAA0651 LFP40 Homo sapiens (Human) actin filament organization [GO:0007015]; asymmetric neuroblast division [GO:0055059]; cell cycle [GO:0007049]; cell morphogenesis [GO:0000902]; cellular hyperosmotic response [GO:0071474]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to tumor necrosis factor [GO:0071356]; innate immune response [GO:0045087]; intracellular protein transport [GO:0006886]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of necroptotic process [GO:0060546]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron migration [GO:2001224]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell population proliferation [GO:0042127]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056] bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; microtubule [GO:0005874]; protein-containing complex [GO:0032991]; ruffle membrane [GO:0032587]; spindle [GO:0005819]; vesicle [GO:0031982] guanyl-nucleotide exchange factor activity [GO:0005085]; microtubule binding [GO:0008017]; small GTPase binding [GO:0031267]; zinc ion binding [GO:0008270] 0.92761 -1.1971 ELASKTREK 0 0 0 0 0 0 0 0 0 0 0 13.272 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92985 IRF7_HUMAN Interferon regulatory factor 7 (IRF-7) IRF7 Homo sapiens (Human) defense response to virus [GO:0051607]; DNA damage response [GO:0006974]; establishment of viral latency [GO:0019043]; immune system process [GO:0002376]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; MDA-5 signaling pathway [GO:0039530]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of adaptive immune response [GO:0002819]; regulation of immune response [GO:0050776]; regulation of monocyte differentiation [GO:0045655]; regulation of MyD88-dependent toll-like receptor signaling pathway [GO:0034124]; regulation of MyD88-independent toll-like receptor signaling pathway [GO:0034127]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of type I interferon production [GO:0032479]; response to virus [GO:0009615]; type I interferon-mediated signaling pathway [GO:0060337] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96768 -2.9378 AGWKTNFR 0 0 0 0 0 0 0 0 0 0 14.1156 13.6847 0 0 0 0 0 0 10.971 0 0 0 0 0 0 0 0 Q92989 CLP1_HUMAN Polyribonucleotide 5'-hydroxyl-kinase Clp1 (EC 2.7.1.78) (Polyadenylation factor Clp1) (Polynucleotide kinase Clp1) (Pre-mRNA cleavage complex II protein Clp1) CLP1 HEAB Homo sapiens (Human) "cerebellar cortex development [GO:0021695]; global gene silencing by mRNA cleavage [GO:0098795]; mRNA 3'-end processing [GO:0031124]; mRNA polyadenylation [GO:0006378]; phosphorylation [GO:0016310]; RISC complex assembly [GO:0070922]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]" cytosol [GO:0005829]; mRNA cleavage factor complex [GO:0005849]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tRNA-intron endonuclease complex [GO:0000214] ATP binding [GO:0005524]; polydeoxyribonucleotide 5'-hydroxyl-kinase activity [GO:0046404]; polynucleotide 5'-hydroxyl-kinase activity [GO:0051731]; polyribonucleotide 5'-hydroxyl-kinase activity [GO:0051736] 0.93326 -1.2654 QAEKEEERGPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9319 Q92993 KAT5_HUMAN Histone acetyltransferase KAT5 (EC 2.3.1.48) (60 kDa Tat-interactive protein) (Tip60) (Histone acetyltransferase HTATIP) (HIV-1 Tat interactive protein) (Lysine acetyltransferase 5) (Protein 2-hydroxyisobutyryltransferase KAT5) (EC 2.3.1.-) (Protein acetyltransferase KAT5) (EC 2.3.1.-) (Protein crotonyltransferase KAT5) (EC 2.3.1.-) (cPLA(2)-interacting protein) KAT5 HTATIP TIP60 Homo sapiens (Human) "apoptotic process [GO:0006915]; cellular response to estradiol stimulus [GO:0071392]; cellular response to glucose starvation [GO:0042149]; cellular response to glucose stimulus [GO:0071333]; cellular senescence [GO:0090398]; DNA damage response [GO:0006974]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA repair-dependent chromatin remodeling [GO:0140861]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; establishment of mitotic spindle orientation [GO:0000132]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; innate immune response [GO:0045087]; internal peptidyl-lysine acetylation [GO:0018393]; lipid droplet disassembly [GO:1905691]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube development [GO:0021915]; neurogenesis [GO:0022008]; nucleotide-excision repair [GO:0006289]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of attachment of mitotic spindle microtubules to kinetochore [GO:1902425]; positive regulation of autophagy [GO:0010508]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of innate immune response [GO:0045089]; positive regulation of mitotic sister chromatid segregation [GO:0062033]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of protein acetylation [GO:1901985]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of triglyceride biosynthetic process [GO:0010867]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of double-strand break repair [GO:2000779]; regulation of hematopoietic stem cell differentiation [GO:1902036]; response to ionizing radiation [GO:0010212]; sperm DNA condensation [GO:0035092]; spermatid development [GO:0007286]" chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; kinetochore [GO:0000776]; mitotic spindle pole [GO:0097431]; NuA4 histone acetyltransferase complex [GO:0035267]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; Piccolo NuA4 histone acetyltransferase complex [GO:0032777]; site of double-strand break [GO:0035861]; Swr1 complex [GO:0000812]; transcription regulator complex [GO:0005667] acetyltransferase activator activity [GO:0010698]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; DNA-binding transcription factor binding [GO:0140297]; histone acetyltransferase activity [GO:0004402]; histone acetyltransferase regulator activity [GO:0035034]; histone H2A acetyltransferase activity [GO:0043998]; histone H2AK5 acetyltransferase activity [GO:0043999]; histone H4 acetyltransferase activity [GO:0010485]; histone H4K16 acetyltransferase activity [GO:0046972]; metal ion binding [GO:0046872]; molecular function activator activity [GO:0140677]; molecular function inhibitor activity [GO:0140678]; peptide 2-hydroxyisobutyryltransferase activity [GO:0106226]; peptide butyryltransferase activity [GO:0140065]; peptide crotonyltransferase activity [GO:0140064]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; phosphatase activator activity [GO:0019211]; protein serine/threonine kinase activator activity [GO:0043539]; transcription coactivator activity [GO:0003713]; transcription regulator activator activity [GO:0140537] 0.88383 -0.32636 GTISFFEIDGRK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.94281 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92994 TF3B_HUMAN "Transcription factor IIIB 90 kDa subunit (TFIIIB90) (hTFIIIB90) (B-related factor 1) (BRF-1) (hBRF) (TAF3B2) (TATA box-binding protein-associated factor, RNA polymerase III, subunit 2)" BRF1 BRF GTF3B TAF3B2 TAF3C Homo sapiens (Human) DNA-templated transcription initiation [GO:0006352]; positive regulation of transcription by RNA polymerase III [GO:0045945]; rRNA transcription [GO:0009303]; transcription by RNA polymerase III [GO:0006383]; transcription initiation at RNA polymerase III promoter [GO:0006384]; transcription preinitiation complex assembly [GO:0070897]; tRNA transcription [GO:0009304] nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor TFIIIB complex [GO:0000126]; transcription preinitiation complex [GO:0097550] metal ion binding [GO:0046872]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III type 3 promoter sequence-specific DNA binding [GO:0001006]; TBP-class protein binding [GO:0017025] 0.93067 -1.249 ELCINAPAIDPCLYIPR 0 0 0 0 0 0 0 0 0 0 0 0 10.552 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q92997 DVL3_HUMAN Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3) DVL3 KIAA0208 Homo sapiens (Human) "canonical Wnt signaling pathway [GO:0060070]; intracellular signal transduction [GO:0035556]; non-canonical Wnt signaling pathway [GO:0035567]; non-canonical Wnt signaling pathway via JNK cascade [GO:0038031]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of GTPase activity [GO:0043547]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein stabilization [GO:0050821]; regulation of protein localization [GO:0032880]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" chromatin [GO:0000785]; cytosol [GO:0005829] beta-catenin binding [GO:0008013]; frizzled binding [GO:0005109]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; small GTPase binding [GO:0031267] 0.90068 -0.695 VTLADFKGVLQRPSYK 0 0 0 0 0 0 0 0 0 0 0 0 11.1266 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q93008 USP9X_HUMAN "Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.4.19.12) (Deubiquitinating enzyme FAF-X) (Fat facets in mammals) (hFAM) (Fat facets protein-related, X-linked) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin-specific-processing protease FAF-X)" USP9X DFFRX FAM USP9 Homo sapiens (Human) "amyloid fibril formation [GO:1990000]; axon extension [GO:0048675]; BMP signaling pathway [GO:0030509]; cell division [GO:0051301]; cell migration [GO:0016477]; chromosome segregation [GO:0007059]; female gamete generation [GO:0007292]; monoubiquitinated protein deubiquitination [GO:0035520]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron migration [GO:0001764]; positive regulation of DNA demethylation [GO:1901537]; positive regulation of protein binding [GO:0032092]; positive regulation of TORC2 signaling [GO:1904515]; protein deubiquitination [GO:0016579]; protein deubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0071947]; protein import into peroxisome matrix, receptor recycling [GO:0016562]; protein K63-linked deubiquitination [GO:0070536]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; transforming growth factor beta receptor signaling pathway [GO:0007179]" cilium [GO:0005929]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; growth cone [GO:0030426]; membrane [GO:0016020]; nucleus [GO:0005634] co-SMAD binding [GO:0070410]; cysteine-type deubiquitinase activity [GO:0004843]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; deubiquitinase activity [GO:0101005]; K48-linked deubiquitinase activity [GO:1990380]; K63-linked deubiquitinase activity [GO:0061578] 0.96938 -6.0408 AVNCREGK 0 12.1482 15.6854 11.842 0 0 0 0 0 9.89339 0 10.7309 0 0 10.8347 0 11.2429 11.6064 0 0 0 8.60641 8.5622 0 9.73127 9.78359 0 Q93009 UBP7_HUMAN Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) USP7 HAUSP Homo sapiens (Human) "monoubiquitinated protein deubiquitination [GO:0035520]; negative regulation of gene expression via CpG island methylation [GO:0044027]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of DNA demethylation [GO:1901537]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of protein stability [GO:0031647]; regulation of retrograde transport, endosome to Golgi [GO:1905279]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of telomere capping [GO:1904353]; rhythmic process [GO:0048511]; transcription-coupled nucleotide-excision repair [GO:0006283]; ubiquitin-dependent protein catabolic process [GO:0006511]" chromosome [GO:0005694]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991] cysteine-type deubiquitinase activity [GO:0004843]; cysteine-type endopeptidase activity [GO:0004197]; deubiquitinase activity [GO:0101005]; K48-linked deubiquitinase activity [GO:1990380]; p53 binding [GO:0002039] 0.9259 -0.96642 EVDYRSDRR 0 0 0 0 0 0 0 0 0 0 8.12552 0 9.47549 0 0 10.0415 0 0 0 0 0 0 0 0 8.93658 11.4593 0 Q93033 IGSF2_HUMAN Immunoglobulin superfamily member 2 (IgSF2) (Cell surface glycoprotein V7) (Glu-Trp-Ile EWI motif-containing protein 101) (EWI-101) (CD antigen CD101) CD101 EWI101 IGSF2 V7 Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; positive regulation of myeloid leukocyte differentiation [GO:0002763] extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886] "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [GO:0016812]" 0.95734 -1.6569 AGYSDLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.19786 0 Q93034 CUL5_HUMAN Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor 1) (VACM-1) CUL5 VACM1 Homo sapiens (Human) ERBB2 signaling pathway [GO:0038128]; G1/S transition of mitotic cell cycle [GO:0000082]; intrinsic apoptotic signaling pathway [GO:0097193]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; site of DNA damage [GO:0090734] calcium channel activity [GO:0005262]; protein-macromolecule adaptor activity [GO:0030674]; signaling receptor activity [GO:0038023]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842] 0.9636 -2.2312 DVFMRYHKAHLTR 0 0 0 0 0 0 9.89166 0 0 0 0 0 0 9.68673 11.1024 0 0 0 0 0 0 9.50772 0 9.36302 0 0 0 Q93045 STMN2_HUMAN Stathmin-2 (Superior cervical ganglion-10 protein) (Protein SCG10) STMN2 SCG10 SCGN10 Homo sapiens (Human) cellular response to nerve growth factor stimulus [GO:1990090]; microtubule depolymerization [GO:0007019]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of neuron projection development [GO:0010977]; neuron projection development [GO:0031175]; positive regulation of microtubule depolymerization [GO:0031117]; positive regulation of neuron projection development [GO:0010976]; regulation of microtubule polymerization or depolymerization [GO:0031110] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471] calcium-dependent protein binding [GO:0048306]; tubulin binding [GO:0015631] 0.16418 0.98857 ALEENNNFSK 0 0 0 0 0 0 0 9.00672 9.12817 9.98542 9.03323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.76653 9.44284 Q93050 VPP1_HUMAN V-type proton ATPase 116 kDa subunit a 1 (V-ATPase 116 kDa subunit a 1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1) ATP6V0A1 ATP6N1 ATP6N1A VPP1 Homo sapiens (Human) endosomal lumen acidification [GO:0048388]; lysosomal lumen acidification [GO:0007042]; proton transmembrane transport [GO:1902600]; regulation of macroautophagy [GO:0016241]; synaptic vesicle lumen acidification [GO:0097401]; toxin transport [GO:1901998]; vacuolar acidification [GO:0007035] "clathrin-coated vesicle membrane [GO:0030665]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; melanosome [GO:0042470]; membrane [GO:0016020]; nuclear speck [GO:0016607]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; proton-transporting V-type ATPase complex [GO:0033176]; secretory granule membrane [GO:0030667]; synaptic vesicle membrane [GO:0030672]; vacuolar proton-transporting V-type ATPase complex [GO:0016471]; vacuolar proton-transporting V-type ATPase, V0 domain [GO:0000220]" "ATPase binding [GO:0051117]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]" 0.93897 -1.3186 ERIPTFERMLWR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2029 0 0 0 0 0 0 0 0 0 0 0 0 Q93052 LPP_HUMAN Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma) LPP Homo sapiens (Human) cell-cell adhesion [GO:0098609] cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; stress fiber [GO:0001725] metal ion binding [GO:0046872] 0.8812 0.015636 GQPFYAVEK 0 0 0 0 0 8.00006 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q93062 RBPMS_HUMAN RNA-binding protein with multiple splicing (RBP-MS) (Heart and RRM expressed sequence) (Hermes) RBPMS HERMES Homo sapiens (Human) positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of SMAD protein signal transduction [GO:0060391]; response to oxidative stress [GO:0006979]; RNA processing [GO:0006396] cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932] mRNA binding [GO:0003729]; poly(A) binding [GO:0008143]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; transcription coactivator activity [GO:0003713] 0.65681 0.39533 ELYLLFRPFK 0 0 0 0 0 0 0 0 0 0 0 0 9.45498 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q93063 EXT2_HUMAN Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 2) (Putative tumor suppressor protein EXT2) EXT2 Homo sapiens (Human) "cellular response to fibroblast growth factor stimulus [GO:0044344]; chondrocyte differentiation [GO:0002062]; endochondral bone morphogenesis [GO:0060350]; fluid transport [GO:0042044]; gene expression [GO:0010467]; glycosaminoglycan biosynthetic process [GO:0006024]; heart contraction [GO:0060047]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; heparin biosynthetic process [GO:0030210]; mesoderm formation [GO:0001707]; multicellular organismal-level water homeostasis [GO:0050891]; ossification [GO:0001503]; polysaccharide biosynthetic process [GO:0000271]; protein N-linked glycosylation [GO:0006487]; regulation of blood pressure [GO:0008217]; signal transduction [GO:0007165]; sodium ion homeostasis [GO:0055078]; sulfation [GO:0051923]; vasodilation [GO:0042311]" endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; UDP-N-acetylglucosamine transferase complex [GO:0043541] glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity [GO:0050508]; glucuronosyltransferase activity [GO:0015020]; glycosyltransferase activity [GO:0016757]; heparan sulfate N-acetylglucosaminyltransferase activity [GO:0042328]; metal ion binding [GO:0046872]; N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity [GO:0050509]; protein heterodimerization activity [GO:0046982] 0.81165 0.22206 ASVVVPEEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0634 0 0 Q93070 NAR4_HUMAN Ecto-ADP-ribosyltransferase 4 (EC 2.4.2.31) (ADP-ribosyltransferase C2 and C3 toxin-like 4) (ARTC4) (Dombrock blood group carrier molecule) (Mono(ADP-ribosyl)transferase 4) (NAD(P)(+)--arginine ADP-ribosyltransferase 4) (CD antigen CD297) ART4 DO DOK1 Homo sapiens (Human) arginine metabolic process [GO:0006525] extracellular region [GO:0005576]; plasma membrane [GO:0005886] NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+-protein-arginine ADP-ribosyltransferase activity [GO:0106274]; nucleotidyltransferase activity [GO:0016779] 0.23654 0.85144 AMASVAR 9.92753 10.0788 10.4942 0 0 0 10.7039 10.8243 10.7961 10.3403 10.7345 10.8882 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q93073 SBP2L_HUMAN Selenocysteine insertion sequence-binding protein 2-like (SECIS-binding protein 2-like) SECISBP2L KIAA0256 Homo sapiens (Human) selenocysteine incorporation [GO:0001514] ribonucleoprotein complex [GO:1990904] mRNA 3'-UTR binding [GO:0003730]; ribonucleoprotein complex binding [GO:0043021]; RNA binding [GO:0003723]; selenocysteine insertion sequence binding [GO:0035368] 0.96409 -2.26 FREYCNQVLCK 0 0 0 9.92682 0 0 0 9.11452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q93074 MED12_HUMAN Mediator of RNA polymerase II transcription subunit 12 (Activator-recruited cofactor 240 kDa component) (ARC240) (CAG repeat protein 45) (Mediator complex subunit 12) (OPA-containing protein) (Thyroid hormone receptor-associated protein complex 230 kDa component) (Trap230) (Trinucleotide repeat-containing gene 11 protein) MED12 ARC240 CAGH45 HOPA KIAA0192 TNRC11 TRAP230 Homo sapiens (Human) "axis elongation involved in somitogenesis [GO:0090245]; embryonic brain development [GO:1990403]; embryonic neurocranium morphogenesis [GO:0048702]; endoderm development [GO:0007492]; heart development [GO:0007507]; neural tube closure [GO:0001843]; oligodendrocyte development [GO:0014003]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; post-anal tail morphogenesis [GO:0036342]; protein ubiquitination [GO:0016567]; Schwann cell development [GO:0014044]; somatic stem cell population maintenance [GO:0035019]; spinal cord development [GO:0021510]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" mediator complex [GO:0016592]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151] beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; nuclear receptor coactivator activity [GO:0030374]; nuclear thyroid hormone receptor binding [GO:0046966]; nuclear vitamin D receptor binding [GO:0042809]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; ubiquitin protein ligase activity [GO:0061630] 0.9245 -0.95225 DNFWLVTAR 11.9835 12.1643 12.1882 0 0 10.2239 11.6298 11.7145 0 0 11.2261 12.9955 0 0 0 0 0 0 0 0 0 10.1261 0 0 0 0 0 Q93075 TATD2_HUMAN Putative deoxyribonuclease TATDN2 (EC 3.1.21.-) TATDN2 KIAA0218 Homo sapiens (Human) nucleoplasm [GO:0005654] metal ion binding [GO:0046872]; nuclease activity [GO:0004518] 0.87606 -0.0086635 LSFQGTFTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5039 0 0 0 0 0 0 0 0 0 Q93083 MT1L_HUMAN Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL) MT1L Homo sapiens (Human) cellular response to copper ion [GO:0071280]; cellular response to zinc ion [GO:0071294]; negative regulation of growth [GO:0045926] cytoplasm [GO:0005737]; nucleus [GO:0005634] zinc ion binding [GO:0008270] 0.8851 -0.14624 DPNCSCATGGSCSCASSCKCK 0 0 8.91701 0 0 0 0 0 0 0 0 10.3548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q93084 AT2A3_HUMAN Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (SERCA3) (SR Ca(2+)-ATPase 3) (EC 7.2.2.10) (Calcium pump 3) ATP2A3 Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; calcium ion transport from cytosol to endoplasmic reticulum [GO:1903515]; intracellular calcium ion homeostasis [GO:0006874]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; monoatomic ion transmembrane transport [GO:0034220]; negative regulation of receptor binding [GO:1900121]; regulation of cardiac conduction [GO:1903779]; transport across blood-brain barrier [GO:0150104] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nuclear membrane [GO:0031965]; organelle membrane [GO:0031090]; platelet dense tubular network membrane [GO:0031095]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; calcium ion transmembrane transporter activity [GO:0015085]; calcium-dependent ATPase activity [GO:0030899]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; metal ion binding [GO:0046872]; P-type calcium transporter activity [GO:0005388]; transmembrane transporter binding [GO:0044325] 0.91692 -0.76643 GVYEKVGEATETALTCLVEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.98157 0 0 0 0 0 0 0 0 0 Q93086 P2RX5_HUMAN P2X purinoceptor 5 (P2X5) (ATP receptor) (Purinergic receptor) P2RX5 P2X5 Homo sapiens (Human) nervous system development [GO:0007399]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; response to ATP [GO:0033198]; signal transduction [GO:0007165] cytosol [GO:0005829]; plasma membrane [GO:0005886]; postsynapse [GO:0098794] ATP binding [GO:0005524]; extracellularly ATP-gated monoatomic cation channel activity [GO:0004931]; monoatomic ion channel activity [GO:0005216]; purinergic nucleotide receptor activity [GO:0001614]; transmembrane signaling receptor activity [GO:0004888] 0.96755 -3.7084 NHIRFPK 0 0 0 0 0 0 0 0 0 0 0 8.43621 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q93088 BHMT1_HUMAN Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5) BHMT Homo sapiens (Human) 'de novo' L-methionine biosynthetic process [GO:0071266]; amino-acid betaine catabolic process [GO:0006579]; amino-acid betaine metabolic process [GO:0006577]; L-methionine salvage [GO:0071267]; protein methylation [GO:0006479]; regulation of homocysteine metabolic process [GO:0050666] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634] betaine-homocysteine S-methyltransferase activity [GO:0047150]; zinc ion binding [GO:0008270] 0.88404 -0.16214 GNYVLEK 0 0 0 0 0 0 0 9.09247 8.97665 0 0 0 0 0 0 0 0 0 0 0 0 9.94092 0 0 0 0 0 Q93097 WNT2B_HUMAN Protein Wnt-2b (Protein Wnt-13) WNT2B WNT13 Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; cellular response to starvation [GO:0009267]; chondrocyte differentiation [GO:0002062]; cornea development in camera-type eye [GO:0061303]; forebrain regionalization [GO:0021871]; hematopoietic stem cell proliferation [GO:0071425]; iris morphogenesis [GO:0061072]; lens development in camera-type eye [GO:0002088]; lung induction [GO:0060492]; male gonad development [GO:0008584]; mesenchymal-epithelial cell signaling [GO:0060638]; neuron differentiation [GO:0030182]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190] collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231] cytokine activity [GO:0005125]; frizzled binding [GO:0005109] 0.9063 -0.72541 ALMNLHNNR 0 8.95204 0 0 0 0 0 0 0 0 0 10.5723 0 0 0 0 0 0 0 0 8.71737 9.10439 0 9.24086 0 0 0 Q93098 WNT8B_HUMAN Protein Wnt-8b WNT8B Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; determination of dorsal identity [GO:0048263]; gastrulation [GO:0007369]; nervous system development [GO:0007399]; neuron differentiation [GO:0030182]; response to estradiol [GO:0032355]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165] extracellular region [GO:0005576]; extracellular space [GO:0005615] cytokine activity [GO:0005125]; frizzled binding [GO:0005109]; receptor ligand activity [GO:0048018] 0.96206 -2.6219 AVKGTMK 0 0 0 0 0 0 0 0 0 0 0 13.5563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q93099 HGD_HUMAN "Homogentisate 1,2-dioxygenase (EC 1.13.11.5) (Homogentisate oxygenase) (Homogentisic acid oxidase) (Homogentisicase)" HGD HGO Homo sapiens (Human) L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572] cytosol [GO:0005829]; extracellular exosome [GO:0070062] "homogentisate 1,2-dioxygenase activity [GO:0004411]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]" 0.91629 -0.84037 DFLIPIAWYEDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.86722 0 0 0 0 0 0 0 Q93100 KPBB_HUMAN Phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta) PHKB Homo sapiens (Human) generation of precursor metabolites and energy [GO:0006091]; glycogen metabolic process [GO:0005977]; protein phosphorylation [GO:0006468] cytosol [GO:0005829]; phosphorylase kinase complex [GO:0005964]; plasma membrane [GO:0005886] calmodulin binding [GO:0005516] 0.80069 0.23952 ISDTEELPEFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.75231 0 0 0 0 Q969F0 FATE1_HUMAN Fetal and adult testis-expressed transcript protein (Cancer/testis antigen 43) (CT43) (Tumor antigen BJ-HCC-2) FATE1 FATE Homo sapiens (Human) apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; negative regulation of mitochondrial calcium ion concentration [GO:0051562] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; mitochondria-associated endoplasmic reticulum membrane [GO:0044233]; mitochondrial outer membrane [GO:0005741] identical protein binding [GO:0042802]; ubiquitin protein ligase binding [GO:0031625] 0.95424 -1.5261 MGSQLPKPRMLR 0 0 0 0 0 0 0 8.88179 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q969F2 NKD2_HUMAN Protein naked cuticle homolog 2 (Naked-2) (hNkd2) NKD2 Homo sapiens (Human) exocytosis [GO:0006887]; Golgi vesicle fusion to target membrane [GO:0048210]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein processing [GO:0010954]; protein localization to plasma membrane [GO:0072659]; Wnt signaling pathway [GO:0016055] basolateral plasma membrane [GO:0016323]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; exocytic vesicle [GO:0070382]; lateral plasma membrane [GO:0016328]; plasma membrane [GO:0005886] ATPase binding [GO:0051117]; calcium ion binding [GO:0005509]; growth factor binding [GO:0019838]; molecular adaptor activity [GO:0060090]; myosin heavy chain binding [GO:0032036]; ubiquitin protein ligase binding [GO:0031625] 0.92391 -1.045 QELPNGDPK 0 0 0 9.80972 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q969F9 HPS3_HUMAN BLOC-2 complex member HPS3 (Hermansky-Pudlak syndrome 3 protein) HPS3 Homo sapiens (Human) intracellular transport [GO:0046907]; melanosome assembly [GO:1903232]; organelle organization [GO:0006996]; platelet dense granule organization [GO:0060155] BLOC-2 complex [GO:0031084]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769] 0.80498 0.23666 ESCGHLGDCYSR 0 0 0 0 0 0 0 0 0 0 10.0444 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q969G2 LHX4_HUMAN LIM/homeobox protein Lhx4 (LIM homeobox protein 4) LHX4 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; medial motor column neuron differentiation [GO:0021526]; motor neuron axon guidance [GO:0008045]; negative regulation of apoptotic process [GO:0043066]; neuron differentiation [GO:0030182]; placenta development [GO:0001890]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; methyl-CpG binding [GO:0008327]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.92753 -1.2009 FILKVLDR 0 0 0 0 0 12.503 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q969H0 FBXW7_HUMAN F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4) FBXW7 FBW7 FBX30 SEL10 Homo sapiens (Human) cellular response to UV [GO:0034644]; DNA damage response [GO:0006974]; DNA repair [GO:0006281]; lipid homeostasis [GO:0055088]; lung development [GO:0030324]; negative regulation of gene expression [GO:0010629]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of osteoclast development [GO:2001205]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; negative regulation of SREBP signaling pathway [GO:2000639]; negative regulation of triglyceride biosynthetic process [GO:0010868]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of circadian rhythm [GO:0042752]; regulation of lipid storage [GO:0010883]; regulation of protein localization [GO:0032880]; rhythmic process [GO:0048511]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; ubiquitin recycling [GO:0010992]; vasculature development [GO:0001944]; vasculogenesis [GO:0001570] chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Parkin-FBXW7-Cul1 ubiquitin ligase complex [GO:1990452]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; SCF ubiquitin ligase complex [GO:0019005] cyclin binding [GO:0030332]; identical protein binding [GO:0042802]; phosphothreonine residue binding [GO:0050816]; protein-macromolecule adaptor activity [GO:0030674]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activator activity [GO:0097027] 0.82956 0.20604 TGQCLQTLQGPNK 0 0 0 0 0 0 0 0 0 0 0 0 9.40869 0 0 0 0 0 0 0 0 0 0 0 0 10.4845 0 Q969H8 MYDGF_HUMAN Myeloid-derived growth factor (MYDGF) MYDGF C19orf10 Homo sapiens (Human) angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794] 0.88856 -0.41259 ESDVPLKTEEFEVTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.90447 0 0 0 0 10.3548 0 0 10.6679 Q969H9 DIRC1_HUMAN Disrupted in renal carcinoma protein 1 (Disrupted in renal cancer protein) DIRC1 Homo sapiens (Human) 0.87622 -0.006511 PEAHMQPAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.83324 0 0 0 Q969I6 S38A4_HUMAN Sodium-coupled neutral amino acid transporter 4 (Amino acid transporter A3) (Na(+)-coupled neutral amino acid transporter 4) (Solute carrier family 38 member 4) (System A amino acid transporter 3) (System N amino acid transporter 3) SLC38A4 ATA3 NAT3 SNAT4 Homo sapiens (Human) amino acid transmembrane transport [GO:0003333]; amino acid transport [GO:0006865]; L-alanine import across plasma membrane [GO:1904273]; neutral amino acid transport [GO:0015804] microvillus membrane [GO:0031528]; plasma membrane [GO:0005886] alanine:sodium symporter activity [GO:0015655]; amino acid transmembrane transporter activity [GO:0015171]; amino acid:sodium symporter activity [GO:0005283]; L-amino acid transmembrane transporter activity [GO:0015179]; L-arginine transmembrane transporter activity [GO:0061459]; neutral L-amino acid:sodium symporter activity [GO:0005295] 0.79957 0.23919 NPAGLDENQAK 0 0 0 0 0 0 0 0 9.25385 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q969J5 I22R2_HUMAN "Interleukin-22 receptor subunit alpha-2 (IL-22 receptor subunit alpha-2) (IL-22R-alpha-2) (IL-22RA2) (Cytokine receptor class-II member 10) (Cytokine receptor family 2 member 10) (CRF2-10) (Cytokine receptor family type 2, soluble 1) (CRF2-S1) (Interleukin-22-binding protein) (IL-22BP) (IL22BP) (ZcytoR16)" IL22RA2 UNQ5793/PRO19598/PRO19822 Homo sapiens (Human) negative regulation of inflammatory response [GO:0050728]; regulation of tyrosine phosphorylation of STAT protein [GO:0042509] cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615] interleukin-22 binding [GO:0042017]; interleukin-22 receptor activity [GO:0042018] 0.72136 0.35796 TLAKYGQRQWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.81874 0 0 Q969K4 ABTB1_HUMAN Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein) ABTB1 BPOZ PP2259 Homo sapiens (Human) cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; ubiquitin ligase complex [GO:0000151] translation elongation factor activity [GO:0003746] 0.69782 0.37907 VLTIEPPPADPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4598 0 10.4376 0 10.2478 10.3375 0 0 0 Q969L2 MAL2_HUMAN Protein MAL2 MAL2 Homo sapiens (Human) myelination [GO:0042552] apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; synaptic vesicle membrane [GO:0030672] structural constituent of myelin sheath [GO:0019911] 0 11.484 SAGGASVPPPPNPAVSFPPPR 0 9.19845 9.0436 0 0 0 9.82413 9.98897 10.4243 0 0 0 0 0 0 0 0 0 0 9.54175 8.80093 0 0 0 10.5542 0 0 Q969N2 PIGT_HUMAN GPI transamidase component PIG-T (Phosphatidylinositol-glycan biosynthesis class T protein) PIGT CGI-06 PSEC0163 UNQ716/PRO1379 Homo sapiens (Human) attachment of GPI anchor to protein [GO:0016255]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182] cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum membrane [GO:0005789]; GPI-anchor transamidase complex [GO:0042765]; membrane [GO:0016020] 0.84727 0.16782 TFHIEEPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.9782 0 0 0 0 0 0 0 0 0 0 Q969P5 FBX32_HUMAN F-box only protein 32 (Atrogin-1) (Muscle atrophy F-box protein) (MAFbx) FBXO32 Homo sapiens (Human) cellular response to dexamethasone stimulus [GO:0071549]; protein ubiquitination [GO:0016567]; response to denervation involved in regulation of muscle adaptation [GO:0014894] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; Z disc [GO:0030018] 0.95542 -1.5797 LVRCYPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.6001 0 0 0 0 0 Q969P6 TOP1M_HUMAN "DNA topoisomerase I, mitochondrial (TOP1mt) (EC 5.6.2.1)" TOP1MT Homo sapiens (Human) DNA replication [GO:0006260]; DNA topological change [GO:0006265] chromosome [GO:0005694]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] "DNA binding [GO:0003677]; DNA topoisomerase type I (single strand cut, ATP-independent) activity [GO:0003917]" 0.96764 -2.7877 AVALYFIDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4387 0 0 0 Q969Q0 RL36L_HUMAN Ribosomal protein eL42-like (60S ribosomal protein L36a-like) (Large ribosomal subunit protein eL42-like) RPL36AL Homo sapiens (Human) translation [GO:0006412] cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634]; plasma membrane [GO:0005886] structural constituent of ribosome [GO:0003735] 0.89892 -0.64693 DSLYAQGRR 0 0 0 0 0 0 0 0 0 0 9.22263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q969Q5 RAB24_HUMAN Ras-related protein Rab-24 RAB24 Homo sapiens (Human) autophagy [GO:0006914]; intracellular protein transport [GO:0006886] autophagosome [GO:0005776]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667] GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.93017 -1.2343 IYYRGAKAAIVCYDLTDSSSFER 0 0 0 9.30945 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.19717 Q969Q6 P2R3C_HUMAN Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma (Protein phosphatase subunit G5PR) (Rhabdomyosarcoma antigen MU-RMS-40.6A/6C) PPP2R3C C14orf10 G5PR Homo sapiens (Human) activation of protein kinase activity [GO:0032147]; B cell homeostasis [GO:0001782]; cortical cytoskeleton organization [GO:0030865]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of B cell differentiation [GO:0045579]; regulation of antimicrobial humoral response [GO:0002759]; regulation of dephosphorylation [GO:0035303]; regulation of mitochondrial depolarization [GO:0051900]; spleen development [GO:0048536]; T cell homeostasis [GO:0043029] centrosome [GO:0005813]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654] metal ion binding [GO:0046872] 0.96354 -2.2 AGAKCKQFFTAK 0 0 0 0 0 11.7911 0 0 0 0 0 0 0 10.3364 0 0 0 0 0 0 0 0 0 0 0 0 0 Q969R2 OSBP2_HUMAN Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (ORP-4) (OSBP-related protein 4) OSBP2 KIAA1664 ORP4 OSBPL4 Homo sapiens (Human) spermatid development [GO:0007286] apical dendrite [GO:0097440]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020] cholesterol binding [GO:0015485]; sterol transporter activity [GO:0015248] 0.88218 -0.063114 DFLELAEIHSRKWQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.6347 9.88759 0 0 0 10.3217 0 10.3746 0 0 0 0 Q969R5 LMBL2_HUMAN Lethal(3)malignant brain tumor-like protein 2 (H-l(3)mbt-like protein 2) (L(3)mbt-like protein 2) L3MBTL2 Homo sapiens (Human) chromatin organization [GO:0006325]; regulation of DNA-templated transcription [GO:0006355] nucleoplasm [GO:0005654]; nucleus [GO:0005634] histone binding [GO:0042393]; methylated histone binding [GO:0035064]; zinc ion binding [GO:0008270] 0.16244 1.0031 MAVVDTVIGGR 0 0 0 0 0 0 0 0 0 9.38769 0 0 0 9.50227 0 0 10.1219 0 0 0 0 0 0 0 0 0 0 Q969R8 ITFG2_HUMAN KICSTOR complex protein ITFG2 (Integrin-alpha FG-GAP repeat-containing protein 2) ITFG2 Homo sapiens (Human) cellular response to amino acid starvation [GO:0034198]; cellular response to glucose starvation [GO:0042149]; germinal center B cell differentiation [GO:0002314]; negative regulation of TORC1 signaling [GO:1904262]; regulation of TOR signaling [GO:0032006] cytosol [GO:0005829]; KICSTOR complex [GO:0140007]; lysosomal membrane [GO:0005765]; nucleoplasm [GO:0005654] 0.85635 0.10274 DTGSPPASEGPTDGSR 0 0 0 9.63212 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q969S2 NEIL2_HUMAN Endonuclease 8-like 2 (EC 3.2.2.-) (EC 4.2.99.18) (DNA glycosylase/AP lyase Neil2) (DNA-(apurinic or apyrimidinic site) lyase Neil2) (Endonuclease VIII-like 2) (Nei homolog 2) (NEH2) (Nei-like protein 2) NEIL2 Homo sapiens (Human) base-excision repair [GO:0006284]; depyrimidination [GO:0045008] cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; mitotic spindle [GO:0072686]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA N-glycosylase activity [GO:0019104]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; microtubule binding [GO:0008017]; zinc ion binding [GO:0008270] 0.64817 0.39618 TLDGSSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.26021 0 0 0 0 0 0 0 Q969S3 ZN622_HUMAN Cytoplasmic 60S subunit biogenesis factor ZNF622 (Zinc finger protein 622) (Zinc finger-like protein 9) ZNF622 ZPR9 Homo sapiens (Human) intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; positive regulation of apoptotic process [GO:0043065]; positive regulation of JNK cascade [GO:0046330]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; ribosomal large subunit biogenesis [GO:0042273] "cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; preribosome, large subunit precursor [GO:0030687]" preribosome binding [GO:1990275]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270] 0.95943 -1.9127 AHYKTDWHR 9.19822 0 0 0 0 0 0 0 0 0 0 9.79098 0 0 0 0 0 0 0 0 0 0 0 0 9.14374 0 0 Q969T3 SNX21_HUMAN Sorting nexin-21 (Sorting nexin L) (SNX-L) SNX21 C20orf161 SNXL Homo sapiens (Human) protein transport [GO:0015031] early endosome membrane [GO:0031901] "phosphatidylinositol phosphate binding [GO:1901981]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]" 0.86408 0.076482 AFEQFLGHLQAVPELR 0 11.0068 10.8062 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q969T4 UB2E3_HUMAN Ubiquitin-conjugating enzyme E2 E3 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E3) (UbcH9) (Ubiquitin carrier protein E3) (Ubiquitin-conjugating enzyme E2-23 kDa) (Ubiquitin-protein ligase E3) UBE2E3 UBCE4 UBCH9 Homo sapiens (Human) protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-protein transferase activity [GO:0004842] 0.88366 -0.12667 AEHDRIARQWTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2528 10.2681 0 0 0 0 0 0 Q969T7 5NT3B_HUMAN 7-methylguanosine phosphate-specific 5'-nucleotidase (7-methylguanosine nucleotidase) (EC 3.1.3.91) (Cytosolic 5'-nucleotidase 3B) (Cytosolic 5'-nucleotidase III-like protein) (cN-III-like protein) (EC 3.1.3.5) (N(7)-methylguanylate 5'-phosphatase) NT5C3B NT5C3L Homo sapiens (Human) exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; nucleotide metabolic process [GO:0009117] cytoplasm [GO:0005737]; cytosol [GO:0005829] 5'-nucleotidase activity [GO:0008253]; magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166] 0.96255 -2.0839 FAYNGKR 9.68564 0 9.84035 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0172 0 0 0 Q969V1 MCHR2_HUMAN Melanin-concentrating hormone receptor 2 (MCH receptor 2) (MCH-R2) (MCHR-2) (G-protein coupled receptor 145) (GPRv17) (MCH-2R) (MCH2) (MCH2R) MCHR2 GPR145 SLT Homo sapiens (Human) neuropeptide signaling pathway [GO:0007218] plasma membrane [GO:0005886] G protein-coupled peptide receptor activity [GO:0008528] 0.92399 -1.0691 EINNMGNTLK 0 0 0 0 0 0 10.7632 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.746 0 0 0 0 Q969V3 NCLN_HUMAN BOS complex subunit NCLN (Nicalin) (Nicastrin-like protein) NCLN Homo sapiens (Human) multi-pass transmembrane protein insertion into ER membrane [GO:0160063]; protein stabilization [GO:0050821]; regulation of protein complex stability [GO:0061635]; regulation of protein-containing complex assembly [GO:0043254]; regulation of signal transduction [GO:0009966] endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; multi-pass translocon complex [GO:0160064]; protein-containing complex [GO:0032991] ribosome binding [GO:0043022] 0.81924 0.21912 LLDFSYEQYQK 0 0 0 0 0 0 0 15.289 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q969V4 TEKT1_HUMAN Tektin-1 TEKT1 Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement involved in cell motility [GO:0060294] axonemal microtubule [GO:0005879]; microtubule cytoskeleton [GO:0015630]; motile cilium [GO:0031514]; nucleus [GO:0005634] 0.86429 0.085694 FLPSEWHIANKNQYHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.24496 0 0 Q969V6 MRTFA_HUMAN Myocardin-related transcription factor A (MRTF-A) (MKL/myocardin-like protein 1) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein) MRTFA KIAA1438 MAL MKL1 Homo sapiens (Human) "actin cytoskeleton organization [GO:0030036]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; smooth muscle cell differentiation [GO:0051145]; wound healing, spreading of cells [GO:0044319]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] actin binding [GO:0003779]; actin monomer binding [GO:0003785]; leucine zipper domain binding [GO:0043522]; transcription coactivator activity [GO:0003713] 0.94927 -1.3716 AGSCCLSPGGR 0 0 0 0 0 0 0 0 0 10.3345 0 10.5349 0 0 0 0 0 0 0 10.3038 0 0 0 0 0 0 0 Q969W0 SPTSA_HUMAN Serine palmitoyltransferase small subunit A (Small subunit of serine palmitoyltransferase A) (ssSPTa) SPTSSA C14orf147 SSSPTA Homo sapiens (Human) ceramide biosynthetic process [GO:0046513]; protein localization [GO:0008104]; sphingolipid biosynthetic process [GO:0030148]; sphingosine biosynthetic process [GO:0046512] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; serine C-palmitoyltransferase complex [GO:0017059] serine C-palmitoyltransferase activity [GO:0004758] 0.64412 0.39623 AGMALAR 0 0 0 0 0 0 0 0 0 0 0 9.60129 0 11.6861 0 11.9845 0 0 0 0 0 0 0 0 0 0 0 Q969W1 ZDH16_HUMAN Palmitoyltransferase ZDHHC16 (EC 2.3.1.225) (Abl-philin 2) (Zinc finger DHHC domain-containing protein 16) (DHHC-16) ZDHHC16 APH2 UNQ2570/PRO6258 Homo sapiens (Human) apoptotic process [GO:0006915]; DNA damage response [GO:0006974]; eye development [GO:0001654]; heart development [GO:0007507]; protein palmitoylation [GO:0018345]; telencephalon development [GO:0021537] endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794] palmitoyltransferase activity [GO:0016409]; protein-cysteine S-palmitoyltransferase activity [GO:0019706] 0.92358 -1.0757 NPYNYGCLDNWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.81853 0 Q969W8 ZN566_HUMAN Zinc finger protein 566 ZNF566 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.56276 0.5104 EIYEIESTQWEIMEK 0 0 8.92875 0 0 0 0 0 0 0 0 0 0 0 0 0 9.45313 0 0 0 0 0 0 0 0 0 0 Q969X5 ERGI1_HUMAN Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ER-Golgi intermediate compartment 32 kDa protein) (ERGIC-32) ERGIC1 ERGIC32 KIAA1181 HT034 Homo sapiens (Human) "endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]" COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654] 0 3.4601 FEGQFSINK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2873 10.3841 0 9.56064 11.2924 9.71963 11.6489 12.0929 12.147 Q969Y0 NXPE3_HUMAN NXPE family member 3 (Protein FAM55C) NXPE3 FAM55C MSTP115 UNQ5791/PRO19596 Homo sapiens (Human) extracellular region [GO:0005576] 0.79429 0.24484 VVDYQNGFYK 0 0 0 0 0 0 0 0 0 12.353 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q969Z0 FAKD4_HUMAN FAST kinase domain-containing protein 4 (Cell cycle progression restoration protein 2) (Cell cycle progression protein 2) (Protein TBRG4) (Transforming growth factor beta regulator 4) TBRG4 CPR2 FASTKD4 KIAA0948 Homo sapiens (Human) mitochondrial mRNA processing [GO:0090615]; mitochondrial RNA processing [GO:0000963]; mRNA metabolic process [GO:0016071]; positive regulation of cell population proliferation [GO:0008284]; regulation of cell cycle [GO:0051726]; regulation of mitochondrial mRNA stability [GO:0044528] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ribonucleoprotein granule [GO:0035770] RNA binding [GO:0003723] 0.9547 -1.522 CTCLLREAAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.6786 0 0 Q969Z3 MARC2_HUMAN Mitochondrial amidoxime reducing component 2 (mARC2) (EC 1.7.-.-) (Molybdenum cofactor sulfurase C-terminal domain-containing protein 2) (MOSC domain-containing protein 2) (Moco sulfurase C-terminal domain-containing protein 2) MTARC2 MARC2 MOSC2 Homo sapiens (Human) cellular detoxification of nitrogen compound [GO:0070458]; detoxification of nitrogen compound [GO:0051410]; nitrate metabolic process [GO:0042126]; nitric oxide biosynthetic process [GO:0006809] mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; peroxisome [GO:0005777] "molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; nitrate reductase activity [GO:0008940]; nitrite reductase activity [GO:0098809]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; pyridoxal phosphate binding [GO:0030170]" 0.96945 -3.056 LWIYPVK 0 0 0 0 0 0 0 0 0 0 0 12.8289 0 0 9.58502 10.9821 0 0 0 0 0 0 0 0 0 0 0 Q96A00 PP14A_HUMAN Protein phosphatase 1 regulatory subunit 14A (17 kDa PKC-potentiated inhibitory protein of PP1) (Protein kinase C-potentiated inhibitor protein of 17 kDa) (CPI-17) PPP1R14A CPI17 PPP1INL Homo sapiens (Human) regulation of phosphorylation [GO:0042325] cytosol [GO:0005829] protein serine/threonine phosphatase inhibitor activity [GO:0004865] 0.96725 -2.7981 AAQRLGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8111 0 0 0 0 0 0 Q96A05 VATE2_HUMAN V-type proton ATPase subunit E 2 (V-ATPase subunit E 2) (Vacuolar proton pump subunit E 2) ATP6V1E2 ATP6E1 ATP6EL2 ATP6V1EL2 Homo sapiens (Human) regulation of macroautophagy [GO:0016241] "acrosomal vesicle [GO:0001669]; cytosol [GO:0005829]; proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]" "proton-transporting ATPase activity, rotational mechanism [GO:0046961]" 0.51701 0.59564 AEEEFNIEK 0 0 0 0 0 0 0 0 0 0 9.84984 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96A09 TET5B_HUMAN Terminal nucleotidyltransferase 5B (EC 2.7.7.19) (Non-canonical poly(A) polymerase FAM46B) TENT5B FAM46B Homo sapiens (Human) mRNA stabilization [GO:0048255]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of translation [GO:0045727] cytoplasm [GO:0005737]; nucleus [GO:0005634] poly(A) RNA polymerase activity [GO:1990817] 0.96953 -4.0846 ALQRYMCSR 0 0 0 0 0 9.87197 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0493 0 0 Q96A19 C102A_HUMAN Coiled-coil domain-containing protein 102A CCDC102A Homo sapiens (Human) myosin complex [GO:0016459] 0.96963 -5.4479 ELEEARAR 0 9.42932 0 0 0 0 0 0 0 0 0 14.0413 0 0 0 0 0 10.0021 0 0 0 0 0 0 10.227 0 0 Q96A23 CPNE4_HUMAN Copine-4 (Copine IV) (Copine-8) CPNE4 Homo sapiens (Human) cellular response to calcium ion [GO:0071277] extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] calcium-dependent phospholipid binding [GO:0005544]; metal ion binding [GO:0046872] 0.80972 0.2251 QVQWECINPK 0 0 0 0 0 0 0 11.1378 0 0 0 0 0 0 0 0 0 0 0 0 0 9.79225 0 0 0 0 0 Q96A28 SLAF9_HUMAN SLAM family member 9 (CD2 family member 10) (CD2F-10) (CD84 homolog 1) (CD84-H1) SLAMF9 CD2F10 UNQ1938/PRO4421 Homo sapiens (Human) T cell activation [GO:0042110] cell surface [GO:0009986]; external side of plasma membrane [GO:0009897] 0.96231 -2.5506 HKMPRMK 0 0 0 0 0 0 0 0 0 0 0 0 12.8772 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96A32 MYL11_HUMAN "Myosin regulatory light chain 11 (Fast skeletal myosin light chain 2) (MLC2B) (Myosin light chain 11) (Myosin regulatory light chain 2, skeletal muscle isoform)" MYL11 HSRLC MYLPF Homo sapiens (Human) actin-myosin filament sliding [GO:0033275]; immune response [GO:0006955]; muscle contraction [GO:0006936]; muscle tissue morphogenesis [GO:0060415]; skeletal muscle tissue development [GO:0007519] cytoplasm [GO:0005737]; cytosol [GO:0005829]; lysosomal membrane [GO:0005765]; muscle myosin complex [GO:0005859] calcium ion binding [GO:0005509]; structural constituent of muscle [GO:0008307] 0.88731 -0.35354 DTFAAMGR 15.3858 15.4896 0 11.6484 0 11.5868 12.3571 0 0 0 0 13.9337 0 0 0 0 10.3214 13.4297 0 0 0 0 0 0 0 8.89367 0 Q96A33 CCD47_HUMAN PAT complex subunit CCDC47 (Calumin) (Coiled-coil domain-containing protein 47) CCDC47 GK001 MSTP041 PSEC0077 Homo sapiens (Human) endoplasmic reticulum calcium ion homeostasis [GO:0032469]; ER overload response [GO:0006983]; ERAD pathway [GO:0036503]; multi-pass transmembrane protein insertion into ER membrane [GO:0160063]; osteoblast differentiation [GO:0001649]; post-embryonic development [GO:0009791]; protein insertion into ER membrane [GO:0045048]; ubiquitin-dependent ERAD pathway [GO:0030433] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; multi-pass translocon complex [GO:0160064]; protein folding chaperone complex [GO:0101031]; rough endoplasmic reticulum membrane [GO:0030867] calcium ion binding [GO:0005509]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; RNA binding [GO:0003723] 0.96777 -2.9913 MMRPVSDQVQIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.40689 10.2207 0 Q96A37 RN166_HUMAN E3 ubiquitin-protein ligase RNF166 (EC 2.3.2.27) (RING finger protein 166) (RING-type E3 ubiquitin transferase RNF166) RNF166 Homo sapiens (Human) autophagy [GO:0006914]; innate immune response [GO:0045087]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630] 0.8846 -0.29869 QLSSYKAPCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3841 0 0 0 0 0 0 0 0 0 Q96A49 SYAP1_HUMAN Synapse-associated protein 1 (BSD domain-containing signal transducer and Akt interactor protein) (BSTA) SYAP1 PRO3113 Homo sapiens (Human) cell differentiation [GO:0030154]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to insulin stimulus [GO:0032869]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; TORC2 signaling [GO:0038203] axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; nucleoplasm [GO:0005654]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202] 0.96781 -2.785 EEKSNGR 10.2531 0 0 0 0 0 0 0 9.77727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96A57 TM230_HUMAN Transmembrane protein 230 TMEM230 C20orf30 HSPC274 UNQ2432/PRO4992 Homo sapiens (Human) synaptic vesicle transport [GO:0048489] autophagosome [GO:0005776]; early endosome [GO:0005769]; endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; late endosome [GO:0005770]; membrane [GO:0016020]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802] 0.9664 -2.3072 GYRGYSYDDIPDFDD 0 0 0 0 0 0 0 0 11.3399 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96A59 MALD3_HUMAN MARVEL domain-containing protein 3 MARVELD3 MRVLDC3 Homo sapiens (Human) bicellular tight junction assembly [GO:0070830]; cell-cell junction organization [GO:0045216]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of JNK cascade [GO:0046329]; protein localization to cell junction [GO:1902414]; protein ubiquitination [GO:0016567]; response to osmotic stress [GO:0006970]; ubiquitin-dependent protein catabolic process [GO:0006511] bicellular tight junction [GO:0005923]; cytoplasmic vesicle [GO:0031410]; membrane [GO:0016020]; nucleus [GO:0005634] mitogen-activated protein kinase kinase kinase binding [GO:0031435]; ubiquitin protein ligase activity [GO:0061630] 0.92772 -1.2218 ERERDPDR 0 0 0 0 0 0 0 0 0 10.79 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96A65 EXOC4_HUMAN Exocyst complex component 4 (Exocyst complex component Sec8) EXOC4 KIAA1699 SEC8 SEC8L1 Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; membrane fission [GO:0090148]; mitotic cytokinesis [GO:0000281]; paraxial mesoderm formation [GO:0048341]; protein transport [GO:0015031]; regulation of macroautophagy [GO:0016241]; vesicle docking involved in exocytosis [GO:0006904]; vesicle tethering involved in exocytosis [GO:0090522] centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; exocyst [GO:0000145]; Flemming body [GO:0090543]; growth cone membrane [GO:0032584]; membrane [GO:0016020]; microvillus [GO:0005902]; myelin sheath abaxonal region [GO:0035748]; plasma membrane [GO:0005886]; synapse [GO:0045202] PDZ domain binding [GO:0030165] 0.96271 -2.629 DELRKLWIEGIEHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4613 0 0 0 0 0 0 0 0 Q96A84 EMID1_HUMAN EMI domain-containing protein 1 (Emilin and multimerin domain-containing protein 1) (Emu1) EMID1 EMU1 Homo sapiens (Human) collagen trimer [GO:0005581]; endoplasmic reticulum [GO:0005783]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794] 0.93277 -1.2856 IVTAREWR 0 0 0 0 9.31306 0 10.0612 0 0 0 0 11.2815 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96A98 TIP39_HUMAN Tuberoinfundibular peptide of 39 residues (TIP39) (Parathyroid hormone 2) PTH2 TIP39 TIPF39 Homo sapiens (Human) neuropeptide signaling pathway [GO:0007218] extracellular region [GO:0005576] 0.96207 -2.5603 LLVLDAP 0 0 0 0 0 0 0 0 0 0 0 0 11.4915 11.3474 11.565 0 0 0 0 0 0 0 0 0 0 0 0 Q96A99 PTX4_HUMAN Pentraxin-4 PTX4 C16orf38 Homo sapiens (Human) extracellular region [GO:0005576] metal ion binding [GO:0046872] 0.95177 -1.3838 VLSGTAPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.56742 0 0 0 0 Q96AA3 RFT1_HUMAN Protein RFT1 homolog RFT1 Homo sapiens (Human) carbohydrate transport [GO:0008643]; dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; glycolipid translocation [GO:0034203] endoplasmic reticulum membrane [GO:0005789] glycolipid floppase activity [GO:0034202] 0.78829 0.24813 LQTLPVSR 0 0 0 0 0 0 0 0 0 0 10.1487 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96AA8 JKIP2_HUMAN Janus kinase and microtubule-interacting protein 2 (CTCL tumor antigen HD-CL-04) (Neuroendocrine long coiled-coil protein 1) JAKMIP2 JAMIP2 KIAA0555 NECC1 Homo sapiens (Human) Golgi apparatus [GO:0005794] kinase binding [GO:0019900]; microtubule binding [GO:0008017] 0.88777 -0.39681 DLEDKTDIQK 0 0 0 0 0 0 0 0 0 0 0 0 0 14.75 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96AC1 FERM2_HUMAN Fermitin family homolog 2 (Kindlin-2) (Mitogen-inducible gene 2 protein) (MIG-2) (Pleckstrin homology domain-containing family C member 1) (PH domain-containing family C member 1) FERMT2 KIND2 MIG2 PLEKHC1 Homo sapiens (Human) "adherens junction maintenance [GO:0034334]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; focal adhesion assembly [GO:0048041]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]; limb development [GO:0060173]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of vascular permeability [GO:0043116]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of GTPase activity [GO:0043547]; positive regulation of integrin activation [GO:0033625]; positive regulation of mesenchymal stem cell proliferation [GO:1902462]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of wound healing, spreading of epidermal cells [GO:1903691]; protein localization to cell junction [GO:1902414]; protein localization to membrane [GO:0072657]; regulation of cell morphogenesis [GO:0022604]; regulation of cell shape [GO:0008360]; substrate adhesion-dependent cell spreading [GO:0034446]; transforming growth factor beta receptor signaling pathway [GO:0007179]; Wnt signaling pathway [GO:0016055]" adherens junction [GO:0005912]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; I band [GO:0031674]; lamellipodium membrane [GO:0031258]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; stress fiber [GO:0001725] "actin binding [GO:0003779]; actin filament binding [GO:0051015]; integrin binding [GO:0005178]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; protein kinase binding [GO:0019901]; SMAD binding [GO:0046332]; type I transforming growth factor beta receptor binding [GO:0034713]" 0.97008 -4.1345 AKINQGWLDSSR 10.1664 10.4185 0 0 0 0 9.77972 0 10.1165 0 0 9.5446 0 0 0 0 0 0 0 11.9727 0 0 0 0 0 0 0 Q96AE4 FUBP1_HUMAN Far upstream element-binding protein 1 (FBP) (FUSE-binding protein 1) (DNA helicase V) (hDH V) FUBP1 Homo sapiens (Human) positive regulation of gene expression [GO:0010628]; regulation of gene expression [GO:0010468] cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] mRNA binding [GO:0003729]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697] 0.59026 0.45452 IGGNEGIDVPIPR 0 0 0 0 0 0 0 0 0 0 9.21667 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6146 Q96AE7 TTC17_HUMAN Tetratricopeptide repeat protein 17 (TPR repeat protein 17) TTC17 Homo sapiens (Human) actin filament polymerization [GO:0030041]; cilium organization [GO:0044782] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886] 0.96086 -1.9984 ALHFSSR 0 0 0 0 0 0 0 0 0 0 0 9.34274 0 0 9.13525 0 0 0 0 0 0 0 0 0 0 0 0 Q96AG3 S2546_HUMAN Mitochondrial outer membrane protein SLC25A46 (Solute carrier family 25 member 46) SLC25A46 TB1 Homo sapiens (Human) autophagy of mitochondrion [GO:0000422]; axon development [GO:0061564]; cerebellar Purkinje cell differentiation [GO:0021702]; cristae formation [GO:0042407]; dendrite development [GO:0016358]; locomotion involved in locomotory behavior [GO:0031987]; mitochondrial fission [GO:0000266]; mitochondrial membrane fission [GO:0090149]; mitochondrial transport [GO:0006839]; myelination in peripheral nervous system [GO:0022011]; optic nerve development [GO:0021554]; peripheral nervous system neuron axonogenesis [GO:0048936]; phospholipid homeostasis [GO:0055091]; protein-containing complex assembly [GO:0065003]; respiratory chain complex IV assembly [GO:0008535]; synapse assembly [GO:0007416] mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739] protein-containing complex binding [GO:0044877] 0.91825 -0.85527 EGIGRVIGMGVPHSK 0 0 13.9878 0 0 0 14.467 14.5661 0 0 10.5725 0 0 0 12.2433 0 0 0 0 0 10.1163 0 0 0 0 0 0 Q96AG4 LRC59_HUMAN "Leucine-rich repeat-containing protein 59 (Ribosome-binding protein p34) (p34) [Cleaved into: Leucine-rich repeat-containing protein 59, N-terminally processed]" LRRC59 PRO1855 Homo sapiens (Human) cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrial nucleoid [GO:0042645]; nuclear envelope [GO:0005635] cadherin binding [GO:0045296]; RNA binding [GO:0003723] 0.36874 0.73794 ELAALPK 0 0 0 0 0 0 0 0 0 10.0577 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.53986 0 0 Q96AH8 RAB7B_HUMAN Ras-related protein Rab-7b RAB7B Homo sapiens (Human) cellular response to type II interferon [GO:0071346]; endosome to lysosome transport [GO:0008333]; late endosome to Golgi transport [GO:0034499]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; phagosome-lysosome fusion [GO:0090385]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein transport [GO:0015031] Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lysosome [GO:0005764]; phagocytic vesicle [GO:0045335]; phagocytic vesicle membrane [GO:0030670]; trans-Golgi network [GO:0005802] GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.93194 -1.2684 FRSMVSTFYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6029 0 0 Q96AJ1 CLUA1_HUMAN Clusterin-associated protein 1 (Qilin) CLUAP1 KIAA0643 Homo sapiens (Human) axoneme assembly [GO:0035082]; cilium assembly [GO:0060271]; floor plate formation [GO:0021508]; heart looping [GO:0001947]; intraciliary anterograde transport [GO:0035720]; neural tube closure [GO:0001843]; smoothened signaling pathway [GO:0007224] centrosome [GO:0005813]; ciliary base [GO:0097546]; ciliary tip [GO:0097542]; cilium [GO:0005929]; intracellular membrane-bounded organelle [GO:0043231]; intraciliary transport particle A [GO:0030991]; intraciliary transport particle B [GO:0030992]; nucleoplasm [GO:0005654] 0.96703 -2.8324 HISMENFR 0 0 0 0 0 0 0 0 10.1611 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96AK3 ABC3D_HUMAN DNA dC->dU-editing enzyme APOBEC-3D (A3D) (A3DE) (EC 3.5.4.38) APOBEC3D APOBEC3DE Homo sapiens (Human) cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529] cytoplasm [GO:0005737]; nucleus [GO:0005634]; P-body [GO:0000932] cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270] 0.95422 -1.5317 FDDNYASLHRTLK 0 9.67453 0 0 0 0 0 0 10.2188 0 0 0 0 0 9.57784 0 0 0 0 0 0 0 0 0 0 0 0 Q96AN5 TM143_HUMAN Transmembrane protein 143 TMEM143 UNQ5922/PRO19813 Homo sapiens (Human) membrane [GO:0016020]; mitochondrion [GO:0005739] 0.35528 0.76149 EPRDWAQQYRER 0 0 15.0275 0 0 0 0 0 0 0 9.95028 0 0 0 0 9.89274 0 0 0 0 0 0 0 0 0 0 0 Q96AP4 ZUP1_HUMAN Zinc finger-containing ubiquitin peptidase 1 (EC 3.4.19.12) (Lys-63-specific deubiquitinase ZUFSP) (DUB) (Zinc finger with UFM1-specific peptidase domain protein) ZUP1 C6orf113 ZUFSP Homo sapiens (Human) cytosol [GO:0005829]; nucleoplasm [GO:0005654] cysteine-type deubiquitinase activity [GO:0004843]; metal ion binding [GO:0046872] 0.56539 0.49052 CHIVDFHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.68995 0 0 0 0 10.0848 0 0 9.57801 0 0 0 Q96AQ1 CC74A_HUMAN Coiled-coil domain-containing protein 74A CCDC74A Homo sapiens (Human) 0.61322 0.42131 SISNSGK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.73547 0 0 0 0 0 0 0 9.09548 0 0 0 0 0 Q96AQ6 PBIP1_HUMAN Pre-B-cell leukemia transcription factor-interacting protein 1 (Hematopoietic PBX-interacting protein) PBXIP1 HPIP Homo sapiens (Human) articular cartilage development [GO:0061975]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; extracellular matrix disassembly [GO:0022617]; gene expression involved in extracellular matrix organization [GO:1901148]; hemopoiesis [GO:0030097]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of Wnt signaling pathway [GO:0030177]; production of molecular mediator involved in inflammatory response [GO:0002532] chromatin [GO:0000785]; cytosol [GO:0005829]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] DNA-binding transcription factor binding [GO:0140297]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714] 0.96936 -5.5309 AEHWKHK 0 0 0 0 0 0 0 0 0 0 0 0 8.43267 8.4102 7.86623 0 0 0 0 0 8.43538 9.42597 0 10.1085 0 0 9.52221 Q96AQ7 CIDEC_HUMAN Lipid transferase CIDEC (Cell death activator CIDE-3) (Cell death-inducing DFFA-like effector protein C) (Fat-specific protein FSP27 homolog) CIDEC FSP27 Homo sapiens (Human) apoptotic process [GO:0006915]; execution phase of apoptosis [GO:0097194]; lipid droplet fusion [GO:0160077]; lipid droplet organization [GO:0034389]; lipid storage [GO:0019915]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of triglyceride metabolic process [GO:0090209]; regulation of apoptotic process [GO:0042981] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; lipid droplet [GO:0005811]; nucleus [GO:0005634] lipid transfer activity [GO:0120013]; molecular condensate scaffold activity [GO:0140693]; phosphatidic acid binding [GO:0070300] 0.87639 -0.006871 ATFYDTYSLSYDLHCCGAK 10.9929 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96AQ8 MCUR1_HUMAN "Mitochondrial calcium uniporter regulator 1 (MCU regulator 1) (Coiled-coil domain-containing protein 90A, mitochondrial)" MCUR1 C6orf79 CCDC90A Homo sapiens (Human) calcium import into the mitochondrion [GO:0036444]; calcium ion import [GO:0070509]; mitochondrial calcium ion transmembrane transport [GO:0006851]; positive regulation of mitochondrial calcium ion concentration [GO:0051561] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] 0.65877 0.39493 SEFSALR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.54678 8.77396 0 Q96AV8 E2F7_HUMAN Transcription factor E2F7 (E2F-7) E2F7 Homo sapiens (Human) "chorionic trophoblast cell differentiation [GO:0060718]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; hepatocyte differentiation [GO:0070365]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cytokinesis [GO:0032466]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071930]; placenta development [GO:0001890]; positive regulation of DNA endoreduplication [GO:0032877]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; sprouting angiogenesis [GO:0002040]; trophoblast giant cell differentiation [GO:0060707]" chromatin [GO:0000785]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; RNA polymerase II transcription regulator complex [GO:0090575] "cis-regulatory region sequence-specific DNA binding [GO:0000987]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity [GO:0001217]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.95427 -1.5014 VAKNQYGWHGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9347 0 0 0 0 0 Q96AX1 VP33A_HUMAN Vacuolar protein sorting-associated protein 33A (hVPS33A) VPS33A Homo sapiens (Human) autophagosome maturation [GO:0097352]; endosomal vesicle fusion [GO:0034058]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; melanosome localization [GO:0032400]; platelet formation [GO:0030220]; regulation of developmental pigmentation [GO:0048070]; regulation of lysosomal lumen pH [GO:0035751]; regulation of SNARE complex assembly [GO:0035542]; vesicle-mediated transport [GO:0016192] autophagosome [GO:0005776]; clathrin-coated vesicle [GO:0030136]; CORVET complex [GO:0033263]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; HOPS complex [GO:0030897]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; perinuclear region of cytoplasm [GO:0048471] 0.96747 -2.8597 DKNFNAVGSVLSK 0 0 0 8.91821 9.21805 0 0 0 0 10.865 9.47381 0 0 0 0 0 9.44481 0 0 0 0 0 0 0 0 0 0 Q96AX9 MIB2_HUMAN E3 ubiquitin-protein ligase MIB2 (EC 2.3.2.27) (Mind bomb homolog 2) (Novel zinc finger protein) (Novelzin) (Putative NF-kappa-B-activating protein 002N) (RING-type E3 ubiquitin transferase MIB2) (Skeletrophin) (Zinc finger ZZ type with ankyrin repeat domain protein 1) MIB2 SKD ZZANK1 Homo sapiens (Human) Notch signaling pathway [GO:0007219]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein ubiquitination [GO:0016567]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803] cytosol [GO:0005829]; early endosome [GO:0005769]; plasma membrane [GO:0005886]; ubiquitin ligase complex [GO:0000151] actin binding [GO:0003779]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.95992 -1.8559 GHALAVR 0 0 0 9.77337 9.89105 10.1053 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96AY2 EME1_HUMAN Crossover junction endonuclease EME1 (EC 3.1.22.-) (MMS4 homolog) (hMMS4) EME1 MMS4 Homo sapiens (Human) double-strand break repair [GO:0006302]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; replication fork processing [GO:0031297]; resolution of meiotic recombination intermediates [GO:0000712]; response to intra-S DNA damage checkpoint signaling [GO:0072429] endodeoxyribonuclease complex [GO:1905347]; heterochromatin [GO:0000792]; Holliday junction resolvase complex [GO:0048476]; nuclear replication fork [GO:0043596]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872] 0.91562 -0.80827 DETTFSFCLESDWAGGVK 0 0 0 0 0 0 0 0 11.2673 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96AY3 FKB10_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP10 (PPIase FKBP10) (EC 5.2.1.8) (65 kDa FK506-binding protein) (65 kDa FKBP) (FKBP-65) (FK506-binding protein 10) (FKBP-10) (Immunophilin FKBP65) (Rotamase) FKBP10 FKBP65 PSEC0056 Homo sapiens (Human) aorta morphogenesis [GO:0035909]; collagen fibril organization [GO:0030199]; extracellular matrix assembly [GO:0085029]; in utero embryonic development [GO:0001701]; peptidyl-lysine hydroxylation [GO:0017185]; peptidyl-proline modification [GO:0018208]; wound healing [GO:0042060] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; membrane [GO:0016020]; mitochondrial intermembrane space [GO:0005758] calcium ion binding [GO:0005509]; FK506 binding [GO:0005528]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755] 0.96007 -1.9781 AQVSEGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0385 0 Q96AY4 TTC28_HUMAN Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) TTC28 KIAA1043 TPRBK Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] cytoplasm [GO:0005737]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; spindle pole [GO:0000922] kinase binding [GO:0019900] 0.82558 0.21354 FYEQQLGLAHQVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4884 0 0 Q96B01 R51A1_HUMAN RAD51-associated protein 1 (HsRAD51AP1) (RAD51-interacting protein) RAD51AP1 PIR51 Homo sapiens (Human) cellular response to ionizing radiation [GO:0071479]; DNA damage response [GO:0006974]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; interstrand cross-link repair [GO:0036297]; meiotic cell cycle [GO:0051321]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of reciprocal meiotic recombination [GO:0010845]; regulation of double-strand break repair via homologous recombination [GO:0010569] "chromatin [GO:0000785]; chromosome [GO:0005694]; chromosome, telomeric region [GO:0000781]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]" D-loop DNA binding [GO:0062037]; DNA binding [GO:0003677]; DNA secondary structure binding [GO:0000217]; double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697] 0.88596 -0.33903 SIEKHGSSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.43867 0 0 0 0 Q96B18 DACT3_HUMAN Dapper homolog 3 (Antagonist of beta-catenin Dapper homolog 3) (Arginine-rich region 1 protein) (Dapper antagonist of catenin 3) DACT3 RRR1 Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; epithelial to mesenchymal transition [GO:0001837]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of Wnt signaling pathway [GO:0030178] cytoplasm [GO:0005737] delta-catenin binding [GO:0070097]; identical protein binding [GO:0042802]; protein kinase A binding [GO:0051018]; protein kinase C binding [GO:0005080] 0.87211 0.028537 GPAPTLAAQAAGSCR 0 0 0 0 0 0 0 0 0 0 0 0 0 8.98416 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96B67 ARRD3_HUMAN Arrestin domain-containing protein 3 (TBP-2-like inducible membrane protein) (TLIMP) ARRDC3 KIAA1376 Homo sapiens (Human) fat pad development [GO:0060613]; heat generation [GO:0031649]; negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071878]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of heat generation [GO:0031651]; negative regulation of locomotion involved in locomotory behavior [GO:0090327]; positive regulation of hippo signaling [GO:0035332]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein transport [GO:0015031]; skin development [GO:0043588] cytoplasm [GO:0005737]; early endosome [GO:0005769]; endosome [GO:0005768]; lysosome [GO:0005764]; plasma membrane [GO:0005886] beta-3 adrenergic receptor binding [GO:0031699] 0.95442 -1.5189 SLKIHAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.514 0 0 0 0 0 Q96B97 SH3K1_HUMAN SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1) SH3KBP1 CIN85 Homo sapiens (Human) actin filament organization [GO:0007015]; apoptotic process [GO:0006915]; cell migration [GO:0016477]; cell-cell signaling [GO:0007267]; cytoskeleton organization [GO:0007010]; endocytosis [GO:0006897]; positive regulation of B cell activation [GO:0050871]; regulation of cell shape [GO:0008360] cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endocytic vesicle [GO:0030139]; focal adhesion [GO:0005925]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; synapse [GO:0045202] SH3 domain binding [GO:0017124]; ubiquitin protein ligase binding [GO:0031625] 0.057851 1.3886 ETTGSESDGGDSSSTK 16.4451 16.2387 16.2322 15.4047 15.618 15.5234 16.2551 16.4231 16.5328 15.687 16.1128 16.0025 0 15.9615 16.0153 16.0045 15.9329 15.503 12.8648 13.0972 13.0004 12.4202 12.2782 12.6642 12.3286 12.0498 0 Q96BA8 CR3L1_HUMAN Cyclic AMP-responsive element-binding protein 3-like protein 1 (cAMP-responsive element-binding protein 3-like protein 1) (Old astrocyte specifically-induced substance) (OASIS) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 1] CREB3L1 OASIS PSEC0238 Homo sapiens (Human) endoplasmic reticulum unfolded protein response [GO:0030968]; extracellular matrix constituent secretion [GO:0070278]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of gene expression [GO:0010629]; negative regulation of sprouting angiogenesis [GO:1903671]; osteoblast differentiation [GO:0001649]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "cAMP response element binding [GO:0035497]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; sequence-specific double-stranded DNA binding [GO:1990837]; SMAD binding [GO:0046332]; transcription cis-regulatory region binding [GO:0000976]" 0.63122 0.40585 EYVECLEK 0 0 0 0 0 0 0 0 0 11.1981 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96BF3 TMIG2_HUMAN Transmembrane and immunoglobulin domain-containing protein 2 (CD28 homolog) (Immunoglobulin and proline-rich receptor 1) (IGPR-1) TMIGD2 CD28H IGPR1 UNQ3059/PRO9879 Homo sapiens (Human) B cell receptor signaling pathway [GO:0050853]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cytokine production [GO:0001819]; T cell costimulation [GO:0031295] B cell receptor complex [GO:0019815] coreceptor activity [GO:0015026] 0.77193 0.27303 RSCQQRDSGNSPGNAFYSNVLYRPR 0 9.05669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96BF6 NACC2_HUMAN Nucleus accumbens-associated protein 2 (NAC-2) (BTB/POZ domain-containing protein 14A) (Repressor with BTB domain and BEN domain) NACC2 BTBD14A NAC2 RBB Homo sapiens (Human) negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter [GO:1900477]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902231]; protein homooligomerization [GO:0051260]; protein-containing complex localization [GO:0031503] chromatin [GO:0000785]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; histone deacetylase binding [GO:0042826]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.95449 -1.5047 KPLDSRVLNAVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.53047 9.92391 0 Q96BM1 ANKR9_HUMAN Ankyrin repeat domain-containing protein 9 ANKRD9 Homo sapiens (Human) intracellular copper ion homeostasis [GO:0006878]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567] Cul5-RING ubiquitin ligase complex [GO:0031466]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829] ubiquitin ligase-substrate adaptor activity [GO:1990756] 0.96413 -2.3912 QCRKSSFAFYQAVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.305 0 0 0 Q96BM9 ARL8A_HUMAN ADP-ribosylation factor-like protein 8A (ADP-ribosylation factor-like protein 10B) (Novel small G protein indispensable for equal chromosome segregation 2) ARL8A ARL10B GIE2 Homo sapiens (Human) anterograde axonal transport [GO:0008089]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; protein transport [GO:0015031] axon cytoplasm [GO:1904115]; azurophil granule membrane [GO:0035577]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; midbody [GO:0030496]; plasma membrane [GO:0005886]; spindle midzone [GO:0051233]; synapse [GO:0045202] alpha-tubulin binding [GO:0043014]; beta-tubulin binding [GO:0048487]; GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.92319 -1.1549 DLPGALDEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6154 0 0 0 0 0 0 0 0 0 Q96BQ1 FAM3D_HUMAN Protein FAM3D FAM3D UNQ567/PRO1130 Homo sapiens (Human) negative regulation of insulin secretion [GO:0046676] extracellular region [GO:0005576]; extracellular space [GO:0005615] cytokine activity [GO:0005125] 0.83685 0.19447 SPFEQFLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.76962 0 0 0 0 0 0 Q96BQ5 CC127_HUMAN Coiled-coil domain-containing protein 127 CCDC127 Homo sapiens (Human) 0.21824 0.89454 RTAAFQQDLEAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.94227 0 0 9.68734 0 0 0 0 Q96BR6 ZN669_HUMAN Zinc finger protein 669 ZNF669 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.89658 -0.52242 AFYFLNSVER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.32773 0 0 Q96BR9 ZBT8A_HUMAN Zinc finger and BTB domain-containing protein 8A (BTB/POZ and zinc-finger domain-containing factor) (BTB/POZ and zinc-finger domains factor on chromosome 1) (BOZ-F1) ZBTB8A BOZF1 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription cis-regulatory region binding [GO:0000976]; transcription coactivator binding [GO:0001223]" 0.95305 -1.4735 LSQPSEVTHYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.14333 0 0 0 0 9.95723 Q96BS2 CHP3_HUMAN Calcineurin B homologous protein 3 (Tescalcin) (TSC) TESC CHP3 Homo sapiens (Human) cell differentiation [GO:0030154]; cellular response to retinoic acid [GO:0071300]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of sodium:proton antiporter activity [GO:0032417]; protein localization to plasma membrane [GO:0072659]; protein maturation [GO:0051604]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of cell adhesion mediated by integrin [GO:0033628] cytoplasm [GO:0005737]; cytosol [GO:0005829]; lamellipodium [GO:0030027]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; ruffle membrane [GO:0032587] calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; phosphatase inhibitor activity [GO:0019212]; protein homodimerization activity [GO:0042803]; protein kinase inhibitor activity [GO:0004860] 0.43925 0.64899 TGFSSDQIEQLHRR 0 0 0 0 0 9.19256 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96BT1 CC049_HUMAN Putative uncharacterized protein C3orf49 C3orf49 Homo sapiens (Human) 0.94546 -1.3414 AVSTNLLK 0 0 0 9.41608 0 9.99152 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96BT7 ALKB8_HUMAN Alkylated DNA repair protein alkB homolog 8 (Probable alpha-ketoglutarate-dependent dioxygenase ABH8) (S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8) (tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8) (EC 2.1.1.229) ALKBH8 ABH8 Homo sapiens (Human) DNA damage response [GO:0006974]; tRNA methylation [GO:0030488]; tRNA wobble uridine modification [GO:0002098] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 2-oxoglutarate-dependent dioxygenase activity [GO:0016706]; iron ion binding [GO:0005506]; tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity [GO:0106335]; tRNA (uracil) methyltransferase activity [GO:0016300]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270] 0.89845 -0.62352 SGSCDACISIAVIHHFATAERR 0 14.4179 0 0 14.0401 0 0 14.8003 0 14.5438 14.4939 0 0 0 0 13.6308 0 0 0 0 0 0 0 0 0 0 0 Q96BW1 UPP_HUMAN Uracil phosphoribosyltransferase homolog UPRT Homo sapiens (Human) cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654] GTP binding [GO:0005525]; ribosylnicotinamide kinase activity [GO:0050262] 0.88295 -0.27001 QIGAQLKLLPMNDQIR 0 0 0 0 0 0 0 9.4253 0 0 0 0 0 12.0761 11.2041 0 0 0 11.0808 11.0314 11.2911 11.0244 0 0 11.9537 11.5808 11.2537 Q96BW9 TAM41_HUMAN "Phosphatidate cytidylyltransferase, mitochondrial (EC 2.7.7.41) (CDP-diacylglycerol synthase) (CDP-DAG synthase) (Mitochondrial translocator assembly and maintenance protein 41 homolog) (TAM41)" TAMM41 C3orf31 Homo sapiens (Human) cardiolipin biosynthetic process [GO:0032049]; CDP-diacylglycerol biosynthetic process [GO:0016024] extrinsic component of membrane [GO:0019898]; extrinsic component of mitochondrial inner membrane [GO:0031314]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] phosphatidate cytidylyltransferase activity [GO:0004605] 0.72225 0.36152 ALYLLGACEMLSFDGHK 11.2532 0 0 0 0 0 0 0 11.474 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96BX8 MOB3A_HUMAN MOB kinase activator 3A (MOB-LAK) (Mob1 homolog 2A) (Mps one binder kinase activator-like 2A) MOB3A MOBKL2A Homo sapiens (Human) positive regulation of protein phosphorylation [GO:0001934]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; nucleus [GO:0005634] metal ion binding [GO:0046872]; protein kinase activator activity [GO:0030295] 0.92901 -1.2282 EFGLIDTK 18.1614 18.3765 17.9538 15.1633 15.1218 15.2364 18.1907 18.1557 18.1786 18.8545 18.7385 18.6665 14.8177 14.85 14.7965 15.9197 16.4157 16.2693 11.1443 12.0771 0 0 11.2279 10.7442 0 0 0 Q96BY2 MOAP1_HUMAN Modulator of apoptosis 1 (MAP-1) (MAP1) (Paraneoplastic antigen Ma4) MOAP1 PNMA4 Homo sapiens (Human) apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; positive regulation of apoptotic process [GO:0043065]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:0001844]; regulation of apoptotic process [GO:0042981] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739] ubiquitin protein ligase binding [GO:0031625] 0.9463 -1.3497 LLEDWCRGMDMNPR 0 0 0 0 0 0 0 9.88728 0 0 0 0 0 0 0 0 9.76719 0 0 0 0 9.10074 0 0 0 0 0 Q96BY6 DOC10_HUMAN Dedicator of cytokinesis protein 10 (Zizimin-3) DOCK10 KIAA0694 ZIZ3 Homo sapiens (Human) B cell homeostasis [GO:0001782]; dendritic spine morphogenesis [GO:0060997]; marginal zone B cell differentiation [GO:0002315]; positive regulation of GTPase activity [GO:0043547]; regulation of cell migration [GO:0030334]; small GTPase mediated signal transduction [GO:0007264] cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] guanyl-nucleotide exchange factor activity [GO:0005085] 0.96897 -6.7212 HANSVDTSFSK 0 0 0 0 0 0 0 0 10.5702 0 0 0 0 0 0 0 0 9.70129 0 10.3334 0 0 0 0 0 0 10.6205 Q96BY7 ATG2B_HUMAN Autophagy-related protein 2 homolog B ATG2B C14orf103 Homo sapiens (Human) autophagosome assembly [GO:0000045]; autophagy of mitochondrion [GO:0000422]; late nucleophagy [GO:0044805]; piecemeal microautophagy of the nucleus [GO:0034727]; reticulophagy [GO:0061709] endoplasmic reticulum membrane [GO:0005789]; lipid droplet [GO:0005811]; phagophore assembly site [GO:0000407]; phagophore assembly site membrane [GO:0034045] lipid transfer activity [GO:0120013]; phosphatidylinositol-3-phosphate binding [GO:0032266] 0.96956 -4.0351 ILSDKSESNTK 10.4148 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.093 Q96BZ8 LENG1_HUMAN Leukocyte receptor cluster member 1 LENG1 Homo sapiens (Human) nucleoplasm [GO:0005654] 0.9607 -1.9852 DNVARVRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.18475 0 0 0 0 0 Q96C00 ZBTB9_HUMAN Zinc finger and BTB domain-containing protein 9 ZBTB9 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.95963 -1.9454 AVLAAASPYFHDK 0 0 0 0 0 0 0 0 0 0 9.29248 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96C03 MID49_HUMAN Mitochondrial dynamics protein MID49 (Mitochondrial dynamics protein of 49 kDa) (Mitochondrial elongation factor 2) (Smith-Magenis syndrome chromosomal region candidate gene 7 protein) MIEF2 MID49 SMCR7 Homo sapiens (Human) mitochondrion organization [GO:0007005]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of protein targeting to membrane [GO:0090314]; regulation of mitochondrion organization [GO:0010821] mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739] 0.96759 -2.9877 DPRCWAVR 9.60783 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96C12 ARMC5_HUMAN Armadillo repeat-containing protein 5 ARMC5 Homo sapiens (Human) "adrenal cortex development [GO:0035801]; anatomical structure morphogenesis [GO:0009653]; CD4-positive, alpha-beta T cell differentiation [GO:0043367]; defense response to virus [GO:0051607]; in utero embryonic development [GO:0001701]; mesoderm formation [GO:0001707]; regulation of steroid biosynthetic process [GO:0050810]; T cell proliferation [GO:0042098]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleoplasm [GO:0005654] 0.88542 -0.37215 ILSRLTCNPACLEAFVR 0 0 0 0 0 0 9.94848 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.208 0 Q96C19 EFHD2_HUMAN EF-hand domain-containing protein D2 (Swiprosin-1) EFHD2 SWS1 Homo sapiens (Human) membrane raft [GO:0045121] cadherin binding [GO:0045296]; calcium ion binding [GO:0005509] 0.96274 -2.1658 KQAEEMKQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2377 0 0 0 0 0 0 0 0 0 0 0 Q96C23 GALM_HUMAN Galactose mutarotase (EC 5.1.3.3) (Aldose 1-epimerase) GALM BLOCK25 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; glucose metabolic process [GO:0006006] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062] aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246] 0.96414 -2.6487 EPNSLHGGVRGFDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.40869 0 0 0 0 0 0 0 0 0 0 Q96C24 SYTL4_HUMAN Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin) SYTL4 Homo sapiens (Human) exocytosis [GO:0006887]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; multivesicular body sorting pathway [GO:0071985]; negative regulation of insulin secretion [GO:0046676]; plasma membrane repair [GO:0001778]; positive regulation of exocytosis [GO:0045921]; positive regulation of protein secretion [GO:0050714]; regulation of plasma membrane repair [GO:1905684] endosome [GO:0005768]; exocytic vesicle [GO:0070382]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; transport vesicle membrane [GO:0030658] metal ion binding [GO:0046872]; neurexin family protein binding [GO:0042043]; phospholipid binding [GO:0005543]; small GTPase binding [GO:0031267] 0.8903 -0.48593 DSLDKSGLFPEWK 0 0 0 0 0 0 0 0 0 0 0 10.2764 0 8.91689 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96C28 ZN707_HUMAN Zinc finger protein 707 ZNF707 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.93328 -1.2843 GFRLDTDDGQLPRAAPER 0 0 0 9.15876 0 0 0 0 9.55298 0 0 0 9.67147 9.94202 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96C34 RUND1_HUMAN RUN domain-containing protein 1 RUNDC1 LP5161 Homo sapiens (Human) in utero embryonic development [GO:0001701] 0.96771 -3.7084 LETQREK 0 0 0 0 0 0 0 0 0 0 12.9141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96C36 P5CR2_HUMAN Pyrroline-5-carboxylate reductase 2 (P5C reductase 2) (P5CR 2) (EC 1.5.1.2) PYCR2 Homo sapiens (Human) cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; proline biosynthetic process [GO:0006561] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] pyrroline-5-carboxylate reductase activity [GO:0004735] 0.8722 0.032971 ELQSMADQEK 0 0 0 0 0 8.25654 0 0 0 0 0 0 0 0 0 9.99887 0 0 0 0 0 0 0 0 0 0 0 Q96C45 ULK4_HUMAN Serine/threonine-protein kinase ULK4 (EC 2.7.11.1) (Unc-51-like kinase 4) ULK4 Homo sapiens (Human) microtubule cytoskeleton organization [GO:0000226]; protein phosphorylation [GO:0006468]; regulation of JNK cascade [GO:0046328]; regulation of MAPK cascade [GO:0043408]; regulation of neuron migration [GO:2001222]; regulation of neuron projection development [GO:0010975]; regulation of p38MAPK cascade [GO:1900744]; regulation of protein kinase C signaling [GO:0090036] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.80722 0.23494 ELLQNSQSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.1335 0 Q96CA5 BIRC7_HUMAN Baculoviral IAP repeat-containing protein 7 (EC 2.3.2.27) (Kidney inhibitor of apoptosis protein) (KIAP) (Livin) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (RING finger protein 50) (RING-type E3 ubiquitin transferase BIRC7) [Cleaved into: Baculoviral IAP repeat-containing protein 7 30kDa subunit (Truncated livin) (p30-Livin) (tLivin)] BIRC7 KIAP LIVIN MLIAP RNF50 UNQ5800/PRO19607/PRO21344 Homo sapiens (Human) lens development in camera-type eye [GO:0002088]; negative regulation of apoptotic process [GO:0043066]; negative regulation of peptidase activity [GO:0010466]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein ubiquitination [GO:0031398]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of natural killer cell apoptotic process [GO:0070247] centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] cysteine-type endopeptidase inhibitor activity [GO:0004869]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.95498 -1.578 GDDPWTEHAK 0 0 0 0 0 0 0 0 0 11.0703 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96CB9 NSUN4_HUMAN 5-methylcytosine rRNA methyltransferase NSUN4 (EC 2.1.1.-) (5-methylcytosine tRNA methyltransferase NSUN4) (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 4) NSUN4 Homo sapiens (Human) rRNA methylation [GO:0031167] mitochondrial large ribosomal subunit [GO:0005762]; mitochondrial matrix [GO:0005759] methyltransferase activity [GO:0008168]; rRNA (cytosine-C5-)-methyltransferase activity [GO:0009383]; rRNA binding [GO:0019843] 0.55916 0.53867 VDLATVPR 10.6723 0 0 0 0 0 0 10.0244 0 11.9832 12.4471 11.9613 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96CC6 RHDF1_HUMAN Inactive rhomboid protein 1 (iRhom1) (Epidermal growth factor receptor-related protein) (Rhomboid 5 homolog 1) (Rhomboid family member 1) (p100hRho) RHBDF1 C16orf8 DIST1 IRHOM1 Homo sapiens (Human) cell migration [GO:0016477]; cell population proliferation [GO:0008283]; negative regulation of protein secretion [GO:0050709]; protein transport [GO:0015031]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of protein secretion [GO:0050708] endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139] growth factor binding [GO:0019838] 0.96916 -4.5049 IDSFVKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.42074 0 10.1109 Q96CD2 COAC_HUMAN Phosphopantothenoylcysteine decarboxylase (PPC-DC) (EC 4.1.1.36) (CoaC) PPCDC COAC MDS018 UNQ9365/PRO34154 Homo sapiens (Human) coenzyme A biosynthetic process [GO:0015937] cytosol [GO:0005829]; phosphopantothenoylcysteine decarboxylase complex [GO:0071513] FMN binding [GO:0010181]; identical protein binding [GO:0042802]; phosphopantothenoylcysteine decarboxylase activity [GO:0004633] 0.84981 0.16559 VASGICDNLLTCVMR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.634 0 0 Q96CF2 CHM4C_HUMAN Charged multivesicular body protein 4c (Chromatin-modifying protein 4c) (CHMP4c) (SNF7 homolog associated with Alix 3) (SNF7-3) (hSnf7-3) (Vacuolar protein sorting-associated protein 32-3) (Vps32-3) (hVps32-3) CHMP4C SHAX3 Homo sapiens (Human) abscission [GO:0009838]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; late endosome to lysosome transport [GO:1902774]; late endosome to vacuole transport via multivesicular body sorting pathway [GO:0032511]; macroautophagy [GO:0016236]; membrane fission [GO:0090148]; midbody abscission [GO:0061952]; mitotic cytokinesis checkpoint signaling [GO:0044878]; mitotic metaphase plate congression [GO:0007080]; multivesicular body assembly [GO:0036258]; multivesicular body sorting pathway [GO:0071985]; multivesicular body-lysosome fusion [GO:0061763]; negative regulation of cell death [GO:0060548]; negative regulation of cytokinesis [GO:0032466]; nuclear membrane reassembly [GO:0031468]; nucleus organization [GO:0006997]; plasma membrane repair [GO:0001778]; protein transport [GO:0015031]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic spindle assembly [GO:1901673]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway [GO:0090611]; vesicle budding from membrane [GO:0006900]; vesicle fusion with vacuole [GO:0051469]; viral budding from plasma membrane [GO:0046761]; viral budding via host ESCRT complex [GO:0039702] amphisome membrane [GO:1904930]; autophagosome membrane [GO:0000421]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; ESCRT III complex [GO:0000815]; Flemming body [GO:0090543]; kinetochore [GO:0000776]; kinetochore microtubule [GO:0005828]; lysosomal membrane [GO:0005765]; midbody [GO:0030496]; multivesicular body [GO:0005771]; multivesicular body membrane [GO:0032585]; nuclear pore [GO:0005643]; plasma membrane [GO:0005886] protein homodimerization activity [GO:0042803] 0.91489 -0.81077 KQEYLENR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.76183 0 0 0 0 Q96CJ1 EAF2_HUMAN ELL-associated factor 2 (Testosterone-regulated apoptosis inducer and tumor suppressor protein) EAF2 TRAITS BM-040 Homo sapiens (Human) apoptotic process [GO:0006915]; epithelial cell proliferation involved in prostate gland development [GO:0060767]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial cell proliferation involved in prostate gland development [GO:0060770]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription elongation by RNA polymerase II [GO:0034243]; transcription elongation by RNA polymerase II [GO:0006368] nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; super elongation complex [GO:0032783]; transcription elongation factor complex [GO:0008023] transcription elongation factor activity [GO:0003711] 0.59897 0.44298 DNSGLLMNTLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.97642 0 0 8.64947 0 0 Q96CM3 RUSD4_HUMAN "Pseudouridylate synthase RPUSD4, mitochondrial (EC 5.4.99.-) (RNA pseudouridylate synthase domain-containing protein 4)" RPUSD4 Homo sapiens (Human) mitochondrial tRNA pseudouridine synthesis [GO:0070902]; mRNA processing [GO:0006397]; mRNA pseudouridine synthesis [GO:1990481]; positive regulation of mitochondrial translation [GO:0070131]; RNA splicing [GO:0008380]; rRNA processing [GO:0006364] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ribonucleoprotein granule [GO:0035770] mitochondrial ribosomal large subunit rRNA binding [GO:1990400]; pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723]; tRNA binding [GO:0000049] 0.96173 -2.5589 LGLEQSKAR 0 0 0 0 0 0 0 0 10.2837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96CM4 NXNL1_HUMAN Nucleoredoxin-like protein 1 (Thioredoxin-like protein 6) NXNL1 TXNL6 Homo sapiens (Human) photoreceptor cell maintenance [GO:0045494] photoreceptor outer segment [GO:0001750] 0.84758 0.1275 AARGGRDPGGGGGEEGGAGGLF 0 0 0 0 0 10.0188 0 0 0 0 0 0 0 0 0 0 9.25378 0 0 0 0 0 0 0 0 0 0 Q96CN4 EVI5L_HUMAN EVI5-like protein (Ecotropic viral integration site 5-like protein) EVI5L Homo sapiens (Human) activation of GTPase activity [GO:0090630]; negative regulation of cilium assembly [GO:1902018]; positive regulation of GTPase activity [GO:0043547] GTPase activator activity [GO:0005096]; small GTPase binding [GO:0031267] 0.90745 -0.71207 DIARTYPEHEFFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.61195 0 0 0 0 0 0 Q96CN5 LRC45_HUMAN Leucine-rich repeat-containing protein 45 LRRC45 Homo sapiens (Human) centrosome [GO:0005813]; cytosol [GO:0005829]; growth cone [GO:0030426]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] 0.96693 -2.8292 AIQAEER 0 0 0 0 0 0 0 0 0 0 0 9.9216 10.188 0 0 0 0 0 0 10.2629 0 0 0 0 0 0 0 Q96CN9 GCC1_HUMAN GRIP and coiled-coil domain-containing protein 1 (Golgi coiled-coil protein 1) GCC1 Homo sapiens (Human) cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138] small GTPase binding [GO:0031267] 0.89906 -0.63751 DLLETIETQKK 0 0 0 0 8.53356 0 0 0 0 0 0 0 9.45886 10.1935 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96CP2 FWCH2_HUMAN FLYWCH family member 2 FLYWCH2 Homo sapiens (Human) RNA binding [GO:0003723] 0.94715 -1.3559 AIEAAPQEPEQKRSR 10.3441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96CP6 ASTRA_HUMAN Protein Aster-A (GRAM domain-containing protein 1A) GRAMD1A KIAA1533 Homo sapiens (Human) autophagy [GO:0006914]; cellular response to cholesterol [GO:0071397]; intracellular sterol transport [GO:0032366] autophagosome [GO:0005776]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-plasma membrane contact site [GO:0140268]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; organelle membrane contact site [GO:0044232]; plasma membrane [GO:0005886] cholesterol binding [GO:0015485]; cholesterol transfer activity [GO:0120020] 0.96218 -2.5435 EVTCLKK 0 0 0 0 0 0 0 0 0 0 0 13.1263 0 0 0 0 0 0 10.5246 8.97722 0 0 0 0 0 0 0 Q96CS2 HAUS1_HUMAN HAUS augmin-like complex subunit 1 (Coiled-coil domain-containing protein 5) (Enhancer of invasion-cluster) (HEI-C) HAUS1 CCDC5 HEIC Homo sapiens (Human) cell division [GO:0051301]; centrosome cycle [GO:0007098]; spindle assembly [GO:0051225] centrosome [GO:0005813]; cytosol [GO:0005829]; HAUS complex [GO:0070652]; mitotic spindle microtubule [GO:1990498]; spindle pole [GO:0000922] 0.9631 -2.6374 ELDSIEAELTR 0 0 0 0 9.94479 0 0 0 0 0 0 0 0 10.6622 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96CS3 FAF2_HUMAN FAS-associated factor 2 (Protein ETEA) (UBX domain-containing protein 3B) (UBX domain-containing protein 8) FAF2 ETEA KIAA0887 UBXD8 UBXN3B Homo sapiens (Human) "lipid droplet organization [GO:0034389]; response to unfolded protein [GO:0006986]; retrograde protein transport, ER to cytosol [GO:0030970]; ubiquitin-dependent ERAD pathway [GO:0030433]" azurophil granule lumen [GO:0035578]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; lipid droplet [GO:0005811]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098] lipase binding [GO:0035473]; lipase inhibitor activity [GO:0055102]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625] 0.95431 -1.5055 LPNDSRVER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.74 Q96CT2 KLH29_HUMAN Kelch-like protein 29 (Kelch repeat and BTB domain-containing protein 9) KLHL29 KBTBD9 KIAA1921 Homo sapiens (Human) 0.76382 0.28665 VCVSFLEK 0 0 0 0 0 0 9.47141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96CT7 CC124_HUMAN Coiled-coil domain-containing protein 124 CCDC124 Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; transcription by RNA polymerase II [GO:0006366] cytosol [GO:0005829]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886] RNA binding [GO:0003723]; transcription coactivator activity [GO:0003713] 0.96995 -3.1071 EWLRSPDNPMNQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0086 0 0 0 0 0 0 0 0 0 0 0 Q96CU9 FXRD1_HUMAN FAD-dependent oxidoreductase domain-containing protein 1 (EC 1.-.-.-) FOXRED1 FP634 Homo sapiens (Human) mitochondrial respiratory chain complex I assembly [GO:0032981] cytoplasm [GO:0005737]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex I [GO:0005747]; mitochondrion [GO:0005739] oxidoreductase activity [GO:0016491] 0.96313 -2.1466 RIHEVHVK 0 0 0 0 0 0 0 0 0 0 0 0 10.5504 0 0 0 0 0 0 8.81295 0 0 9.71586 0 10.4485 0 0 Q96CV9 OPTN_HUMAN Optineurin (E3-14.7K-interacting protein) (FIP-2) (Huntingtin yeast partner L) (Huntingtin-interacting protein 7) (HIP-7) (Huntingtin-interacting protein L) (NEMO-related protein) (Optic neuropathy-inducing protein) (Transcription factor IIIA-interacting protein) (TFIIIA-IntP) OPTN FIP2 GLC1E HIP7 HYPL NRP Homo sapiens (Human) autophagy [GO:0006914]; cell death [GO:0008219]; cellular response to unfolded protein [GO:0034620]; defense response to Gram-negative bacterium [GO:0050829]; Golgi organization [GO:0007030]; Golgi ribbon formation [GO:0090161]; Golgi to plasma membrane protein transport [GO:0043001]; innate immune response [GO:0045087]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of receptor recycling [GO:0001920]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; positive regulation of autophagy [GO:0010508]; positive regulation of xenophagy [GO:1904417]; protein localization to Golgi apparatus [GO:0034067]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; signal transduction [GO:0007165] autophagosome [GO:0005776]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome membrane [GO:0055038]; trans-Golgi network [GO:0005802] identical protein binding [GO:0042802]; K63-linked polyubiquitin modification-dependent protein binding [GO:0070530]; metal ion binding [GO:0046872]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein-macromolecule adaptor activity [GO:0030674] 0.95352 -1.4956 ELSEKLELAEK 0 0 0 0 0 0 0 0 12.5874 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7469 Q96CW1 AP2M1_HUMAN AP-2 complex subunit mu (AP-2 mu chain) (Adaptin-mu2) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Plasma membrane adaptor AP-2 50 kDa protein) AP2M1 CLAPM1 KIAA0109 Homo sapiens (Human) clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; negative regulation of protein localization to plasma membrane [GO:1903077]; positive regulation of receptor internalization [GO:0002092]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; protein-containing complex assembly [GO:0065003]; receptor internalization [GO:0031623]; regulation of vesicle size [GO:0097494]; synaptic vesicle endocytosis [GO:0048488]; vesicle budding from membrane [GO:0006900]; vesicle-mediated transport [GO:0016192] AP-2 adaptor complex [GO:0030122]; clathrin-coated endocytic vesicle [GO:0045334]; clathrin-coated endocytic vesicle membrane [GO:0030669]; clathrin-coated pit [GO:0005905]; cytoplasmic side of plasma membrane [GO:0009898]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endolysosome membrane [GO:0036020]; extracellular exosome [GO:0070062]; extrinsic component of presynaptic endocytic zone membrane [GO:0098894]; glutamatergic synapse [GO:0098978]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; postsynapse [GO:0098794] clathrin adaptor activity [GO:0035615]; disordered domain specific binding [GO:0097718]; lipid binding [GO:0008289]; low-density lipoprotein particle receptor binding [GO:0050750]; signal sequence binding [GO:0005048]; transmembrane transporter binding [GO:0044325] 0.61699 0.41801 ASENAIVWK 0 0 0 0 0 0 0 0 8.76158 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96CW5 GCP3_HUMAN Gamma-tubulin complex component 3 (GCP-3) (hGCP3) (Gamma-ring complex protein 104 kDa) (h104p) (hGrip104) (Spindle pole body protein Spc98 homolog) (hSpc98) TUBGCP3 GCP3 Homo sapiens (Human) cytoplasmic microtubule organization [GO:0031122]; meiotic cell cycle [GO:0051321]; microtubule nucleation [GO:0007020]; mitotic cell cycle [GO:0000278]; single fertilization [GO:0007338]; spindle assembly [GO:0051225] centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; equatorial microtubule organizing center [GO:0000923]; gamma-tubulin complex [GO:0000930]; membrane [GO:0016020]; polar microtubule [GO:0005827]; spindle [GO:0005819] gamma-tubulin binding [GO:0043015]; structural constituent of cytoskeleton [GO:0005200]; structural molecule activity [GO:0005198] 0.96984 -5.9984 KLHSQGVLKNK 0 0 0 0 0 0 0 0 0 0 0 14.7342 0 0 0 0 0 0 0 0 0 0 0 9.52282 0 0 0 Q96CW9 NTNG2_HUMAN Netrin-G2 (Laminet-2) NTNG2 KIAA1857 LMNT2 UNQ9381/PRO34206 Homo sapiens (Human) axonogenesis [GO:0007409]; modulation of chemical synaptic transmission [GO:0050804]; postsynaptic specialization assembly [GO:0098698]; regulation of neuron migration [GO:2001222]; regulation of neuron projection arborization [GO:0150011]; regulation of neuron projection development [GO:0010975]; regulation of presynapse assembly [GO:1905606]; synaptic membrane adhesion [GO:0099560] axon [GO:0030424]; extracellular region [GO:0005576]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; presynaptic active zone membrane [GO:0048787]; Schaffer collateral - CA1 synapse [GO:0098685] 0.58914 0.4645 EGAAGPK 0 0 0 0 0 0 0 0 0 0 8.62472 0 0 0 0 0 9.49133 0 10.2891 0 0 0 0 0 0 0 0 Q96CX2 KCD12_HUMAN BTB/POZ domain-containing protein KCTD12 (Pfetin) (Predominantly fetal expressed T1 domain) KCTD12 C13orf2 KIAA1778 PFET1 Homo sapiens (Human) protein homooligomerization [GO:0051260]; regulation of G protein-coupled receptor signaling pathway [GO:0008277] cell projection [GO:0042995]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734] identical protein binding [GO:0042802]; RNA binding [GO:0003723] 0.90552 -0.72386 DGFLFRYILDYLR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.86963 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96D09 GASP2_HUMAN G-protein coupled receptor-associated sorting protein 2 (GASP-2) GPRASP2 Homo sapiens (Human) hematopoietic stem cell homeostasis [GO:0061484] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] amyloid-beta binding [GO:0001540]; G protein-coupled receptor binding [GO:0001664] 0.81682 0.22099 DPFIHEISK 0 0 0 11.8721 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96D15 RCN3_HUMAN Reticulocalbin-3 (EF-hand calcium-binding protein RLP49) RCN3 UNQ239/PRO272 Homo sapiens (Human) collagen biosynthetic process [GO:0032964]; ERAD pathway [GO:0036503]; lung epithelium development [GO:0060428]; phospholipid homeostasis [GO:0055091]; positive regulation of peptidase activity [GO:0010952]; protein secretion [GO:0009306]; protein transport [GO:0015031]; regulation of protein kinase B signaling [GO:0051896]; surfactant homeostasis [GO:0043129] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; intracellular membrane-bounded organelle [GO:0043231] calcium ion binding [GO:0005509] 0.39005 0.71155 DIVIAETLEDLDR 0 0 0 0 0 8.89096 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3457 9.214 0 0 Q96D53 COQ8B_HUMAN "Atypical kinase COQ8B, mitochondrial (EC 2.7.-.-) (AarF domain-containing protein kinase 4) (Coenzyme Q protein 8B)" COQ8B ADCK4 Homo sapiens (Human) cerebellar Purkinje cell layer morphogenesis [GO:0021692]; phosphorylation [GO:0016310]; ubiquinone biosynthetic process [GO:0006744] cytosol [GO:0005829]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; kinase activity [GO:0016301]; lipid binding [GO:0008289] 0.13144 1.0616 KSMPGGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.94506 9.49059 9.26672 0 Q96D70 R3HD4_HUMAN R3H domain-containing protein 4 R3HDM4 C19orf22 Homo sapiens (Human) nucleus [GO:0005634] nucleic acid binding [GO:0003676] 0.84848 0.12521 LLPLPSCLPALASSQVK 0 9.59993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.99067 0 0 0 0 0 0 0 0 0 0 Q96D98 EID2B_HUMAN EP300-interacting inhibitor of differentiation 2B (EID-2B) (EID-2-like inhibitor of differentiation 3) (EID-3) EID2B EID3 Homo sapiens (Human) cell differentiation [GO:0030154]; muscle organ development [GO:0007517]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of myoblast differentiation [GO:0045662] nucleoplasm [GO:0005654]; nucleus [GO:0005634] identical protein binding [GO:0042802]; transcription corepressor activity [GO:0003714] 0.95506 -1.5659 LLRDFEER 0 8.34216 0 0 0 0 0 0 9.91883 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96DA6 TIM14_HUMAN Mitochondrial import inner membrane translocase subunit TIM14 (DnaJ homolog subfamily C member 19) DNAJC19 TIM14 TIMM14 Homo sapiens (Human) genitalia development [GO:0048806]; intracellular protein transport [GO:0006886]; protein folding [GO:0006457]; protein import into mitochondrial matrix [GO:0030150]; protein targeting to mitochondrion [GO:0006626]; regulation of cardiolipin metabolic process [GO:1900208]; visual perception [GO:0007601] "inner mitochondrial membrane protein complex [GO:0098800]; matrix side of mitochondrial inner membrane [GO:0099617]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; PAM complex, Tim23 associated import motor [GO:0001405]; protein-containing complex [GO:0032991]; TIM23 mitochondrial import inner membrane translocase complex [GO:0005744]" ATPase activator activity [GO:0001671] 0.62293 0.41303 QVFQSLPK 0 0 0 0 0 0 0 0 0 0 0 11.3104 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96DB2 HDA11_HUMAN Histone deacetylase 11 (HD11) (EC 3.5.1.98) HDAC11 Homo sapiens (Human) chromatin organization [GO:0006325]; histone deacetylation [GO:0016575]; oligodendrocyte development [GO:0014003] histone deacetylase complex [GO:0000118]; nucleus [GO:0005634]; plasma membrane [GO:0005886] DNA-binding transcription factor binding [GO:0140297]; histone deacetylase activity [GO:0004407] 0.72743 0.34834 DELVFRMVRGR 8.64613 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96DB5 RMD1_HUMAN Regulator of microtubule dynamics protein 1 (RMD-1) (hRMD-1) (Protein FAM82B) RMDN1 FAM82B CGI-90 Homo sapiens (Human) attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; mitotic spindle organization [GO:0007052] cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; mitotic spindle pole [GO:0097431]; spindle microtubule [GO:0005876] microtubule binding [GO:0008017] 0.92553 -0.96905 GAAPGSR 9.61602 0 0 0 0 0 0 0 0 0 0 0 8.74106 0 0 0 8.27803 0 0 0 8.63829 0 0 0 0 0 0 Q96DC7 TMCO6_HUMAN Transmembrane and coiled-coil domain-containing protein 6 TMCO6 PRO1580 Homo sapiens (Human) protein import into nucleus [GO:0006606] membrane [GO:0016020] nuclear import signal receptor activity [GO:0061608] 0.85403 0.10519 GLQHPETQQTFIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8003 0 0 0 0 0 0 Q96DD0 LRC39_HUMAN Leucine-rich repeat-containing protein 39 (Myosin-interacting M-band-associated stress-responsive protein) (Myomasp) LRRC39 UNQ6500/PRO21368 Homo sapiens (Human) M band [GO:0031430] 0.96947 -4.1014 EVWEKRIK 0 0 0 0 0 0 0 0 0 0 0 9.90872 0 0 0 0 0 0 0 0 0 0 0 9.55877 0 0 10.9353 Q96DF8 ESS2_HUMAN Splicing factor ESS-2 homolog (DiGeorge syndrome critical region 13) (DiGeorge syndrome critical region 14) (DiGeorge syndrome protein H) (DGS-H) (Protein ES2) ESS2 DGCR13 DGCR14 DGSH DGSI ES2 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; nervous system development [GO:0007399]" catalytic step 2 spliceosome [GO:0071013]; nucleus [GO:0005634] 0.9624 -2.0322 DFFPDVEKLQAQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.26505 0 0 0 0 0 0 0 0 Q96DG6 CMBL_HUMAN Carboxymethylenebutenolidase homolog (EC 3.1.-.-) CMBL Homo sapiens (Human) xenobiotic metabolic process [GO:0006805] cytosol [GO:0005829]; extracellular exosome [GO:0070062] hydrolase activity [GO:0016787] 0.96969 -3.9442 EVQVEHIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.89151 10.9337 0 0 0 0 Q96DI7 SNR40_HUMAN U5 small nuclear ribonucleoprotein 40 kDa protein (U5 snRNP 40 kDa protein) (U5-40K) (38 kDa-splicing factor) (Prp8-binding protein) (hPRP8BP) (U5 snRNP-specific 40 kDa protein) (WD repeat-containing protein 57) SNRNP40 PRP8BP SFP38 WDR57 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]" catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; sno(s)RNA-containing ribonucleoprotein complex [GO:0005732]; U2-type catalytic step 2 spliceosome [GO:0071007]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682] RNA binding [GO:0003723] 0.91567 -0.77218 TVAVWDSETGERVK 0 0 0 0 0 0 0 0 11.9957 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96DL1 NXPE2_HUMAN NXPE family member 2 (Protein FAM55B) NXPE2 FAM55B Homo sapiens (Human) membrane [GO:0016020] 0.96853 -3.6089 ARMYSTALMAGASGK 18.1614 18.1606 0 15.7999 16.2025 16.5167 17.8747 0 10.5836 18.8534 0 10.4738 10.15 14.75 0 16.7043 0 0 0 11.1595 0 9.90064 11.2279 12.4238 0 0 0 Q96DM1 PGBD4_HUMAN PiggyBac transposable element-derived protein 4 PGBD4 Homo sapiens (Human) 0.96721 -2.3518 FCGELMALK 0 0 0 0 0 0 0 0 8.67546 0 0 0 0 0 0 0 0 0 9.99534 0 0 0 0 0 0 0 0 Q96DM3 RMC1_HUMAN Regulator of MON1-CCZ1 complex (Colon cancer-associated protein Mic1) (Mic-1) (WD repeat-containing protein 98) RMC1 C18orf8 MIC1 WDR98 Homo sapiens (Human) autophagy [GO:0006914]; regulation of autophagy [GO:0010506] late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; Mon1-Ccz1 complex [GO:0035658] 0.95514 -1.5645 FFEQRNQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.13373 0 Q96DN2 VWCE_HUMAN von Willebrand factor C and EGF domain-containing protein (HBV X protein up-regulated gene 11 protein) (HBxAg up-regulated gene 11 protein) VWCE URG11 Homo sapiens (Human) cellular response to virus [GO:0098586] cytoplasm [GO:0005737]; extracellular region [GO:0005576] calcium ion binding [GO:0005509] 0.96167 -2.5603 NSIGSYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.08786 0 0 0 0 0 9.16383 0 0 0 0 0 Q96DN5 TBC31_HUMAN TBC1 domain family member 31 (WD repeat-containing protein 67) TBC1D31 WDR67 Homo sapiens (Human) cilium assembly [GO:0060271] centriolar satellite [GO:0034451]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737] molecular adaptor activity [GO:0060090] 0.95422 -1.5149 LIEAGETQSQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14.938 0 0 0 0 0 0 9.07518 0 0 Q96DR7 ARHGQ_HUMAN Rho guanine nucleotide exchange factor 26 (SH3 domain-containing guanine exchange factor) ARHGEF26 SGEF HMFN1864 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; endothelial cell morphogenesis [GO:0001886]; ruffle assembly [GO:0097178] cytosol [GO:0005829]; ruffle [GO:0001726] guanyl-nucleotide exchange factor activity [GO:0005085] 0.94612 -1.3446 KGLSQTVSQEERK 0 9.92078 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96DT5 DYH11_HUMAN Dynein axonemal heavy chain 11 (Axonemal beta dynein heavy chain 11) (Ciliary dynein heavy chain 11) DNAH11 Homo sapiens (Human) cardiac septum morphogenesis [GO:0060411]; cilium movement [GO:0003341]; determination of left/right asymmetry in nervous system [GO:0035545]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; flagellated sperm motility [GO:0030317]; learning or memory [GO:0007611]; protein localization to motile cilium [GO:0120229]; regulation of cilium beat frequency [GO:0003356] 9+0 motile cilium [GO:0097728]; 9+2 motile cilium [GO:0097729]; axoneme [GO:0005930]; dynein complex [GO:0030286]; extracellular region [GO:0005576]; microtubule [GO:0005874]; motile cilium [GO:0031514]; proximal portion of axoneme [GO:0120134] ATP binding [GO:0005524]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; minus-end-directed microtubule motor activity [GO:0008569] 0.96956 -5.6316 AEPALVAATAALNTLNR 0 0 9.05336 0 0 0 0 10.3881 0 9.9345 0 0 0 11.1243 9.30072 0 8.78774 0 0 8.76315 0 9.39015 10.0512 0 9.71917 11.408 0 Q96DT6 ATG4C_HUMAN Cysteine protease ATG4C (EC 3.4.22.-) (AUT-like 3 cysteine endopeptidase) (Autophagy-related cysteine endopeptidase 3) (Autophagin-3) (Autophagy-related protein 4 homolog C) (HsAPG4C) ATG4C APG4C AUTL1 AUTL3 Homo sapiens (Human) autophagy [GO:0006914]; protein delipidation [GO:0051697]; protein transport [GO:0015031]; proteolysis [GO:0006508] cytoplasm [GO:0005737] Atg8-specific peptidase activity [GO:0019786]; cysteine-type peptidase activity [GO:0008234] 0.92374 -1.0446 CYHFKYEDEDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.87123 0 0 0 0 0 0 0 Q96DT7 ZBT10_HUMAN Zinc finger and BTB domain-containing protein 10 (Zinc finger protein RIN ZF) ZBTB10 RINZF RINZFC Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] "chromosome, telomeric region [GO:0000781]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]" "DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; telomeric DNA binding [GO:0042162]" 0.88371 -0.069369 GPATVDLELDALEGK 0 0 0 0 0 8.91139 0 0 0 0 11.3121 0 0 10.9968 0 0 10.225 0 0 0 0 0 0 0 0 0 9.86885 Q96DU9 PABP5_HUMAN Polyadenylate-binding protein 5 (PABP-5) (Poly(A)-binding protein 5) PABPC5 PABP5 Homo sapiens (Human) cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266] 0.96963 -4.9608 AVLDLHGK 8.93192 0 0 9.47557 0 0 0 0 0 0 0 10.3681 0 0 0 0 0 0 0 0 9.87575 0 0 0 0 0 0 Q96DV4 RM38_HUMAN "Large ribosomal subunit protein mL38 (39S ribosomal protein L38, mitochondrial) (L38mt) (MRP-L38)" MRPL38 HSPC262 Homo sapiens (Human) mitochondrial translation [GO:0032543] mitochondrial inner membrane [GO:0005743]; mitochondrial large ribosomal subunit [GO:0005762]; mitochondrion [GO:0005739] 0.95969 -1.8853 EYFGEKTDPK 0 0 0 0 0 0 0 0 9.58184 0 0 0 0 0 0 0 0 8.54616 0 0 0 0 0 0 0 0 9.38963 Q96DY2 DRC10_HUMAN Dynein regulatory complex protein 10 (IQ domain-containing protein D) IQCD DRC10 Homo sapiens (Human) ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; motile cilium [GO:0031514] 0.11828 1.0858 AQFLQDISR 0 0 0 9.22318 0 0 0 0 0 0 9.39633 0 0 0 9.09355 0 0 0 0 0 0 0 0 0 0 0 0 Q96DY7 MTBP_HUMAN Mdm2-binding protein (hMTBP) MTBP Homo sapiens (Human) cell cycle [GO:0007049]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of mitotic nuclear division [GO:0045839]; protein localization to kinetochore [GO:0034501]; regulation of protein ubiquitination [GO:0031396]; traversing start control point of mitotic cell cycle [GO:0007089] chromatin [GO:0000785]; kinetochore [GO:0000776] 0.96222 -2.5511 SKDLNCLYPRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3814 Q96DZ5 CLIP3_HUMAN CAP-Gly domain-containing linker protein 3 (Cytoplasmic linker protein 170-related 59 kDa protein) (CLIP-170-related 59 kDa protein) (CLIPR-59) CLIP3 CLIPR59 Homo sapiens (Human) cytoplasmic microtubule organization [GO:0031122]; fat cell differentiation [GO:0045444]; membrane biogenesis [GO:0044091]; negative regulation of microtubule polymerization [GO:0031115]; peptidyl-L-cysteine S-palmitoylation [GO:0018230]; positive regulation of apoptotic process [GO:0043065]; positive regulation of endocytosis [GO:0045807]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; protein transport along microtubule [GO:0098840] cell cortex [GO:0005938]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; Golgi stack [GO:0005795]; membrane raft [GO:0045121]; microtubule plus-end [GO:0035371]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588] ganglioside binding [GO:0035594]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010] 0.8984 -0.56775 IGGSTDSPGDSVGAKK 0 0 8.5129 0 0 0 0 8.33445 0 0 9.18515 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96DZ9 CKLF5_HUMAN CKLF-like MARVEL transmembrane domain-containing protein 5 (Chemokine-like factor superfamily member 5) CMTM5 CKLFSF5 Homo sapiens (Human) chemotaxis [GO:0006935]; negative regulation of myoblast differentiation [GO:0045662] extracellular space [GO:0005615]; membrane [GO:0016020] cytokine activity [GO:0005125] 0.94754 -1.3483 LSARDRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.7174 0 0 0 Q96E22 NGBR_HUMAN Dehydrodolichyl diphosphate synthase complex subunit NUS1 (EC 2.5.1.87) (Cis-prenyltransferase subunit NgBR) (Nogo-B receptor) (NgBR) (Nuclear undecaprenyl pyrophosphate synthase 1 homolog) NUS1 C6orf68 NGBR Homo sapiens (Human) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cholesterol homeostasis [GO:0042632]; dolichol biosynthetic process [GO:0019408]; dolichyl diphosphate biosynthetic process [GO:0006489]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of nitric-oxide synthase activity [GO:0051000]; protein glycosylation [GO:0006486]; protein mannosylation [GO:0035268]; regulation of intracellular cholesterol transport [GO:0032383]; vascular endothelial growth factor signaling pathway [GO:0038084] dehydrodolichyl diphosphate synthase complex [GO:1904423]; endoplasmic reticulum membrane [GO:0005789] dehydrodolichyl diphosphate synthase activity [GO:0045547]; metal ion binding [GO:0046872] 0.96896 -3.3761 TLTSWLR 0 0 0 0 0 0 0 0 0 0 0 8.7785 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96E39 RMXL1_HUMAN "RNA binding motif protein, X-linked-like-1 (Heterogeneous nuclear ribonucleoprotein G-like 1)" RBMXL1 Homo sapiens (Human) "mRNA processing [GO:0006397]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; RNA splicing [GO:0008380]" spliceosomal complex [GO:0005681] RNA binding [GO:0003723] 0.076471 1.266 DRDYSDHPSGGSYR 0 0 0 0 0 0 0 0 0 0 8.49117 8.64292 0 0 0 9.02652 0 0 0 9.21868 0 0 0 0 0 11.6751 9.56784 Q96E40 SACA9_HUMAN Sperm acrosome-associated protein 9 SPACA9 C9orf9 Homo sapiens (Human) axoneme assembly [GO:0035082] acrosomal vesicle [GO:0001669]; axonemal microtubule [GO:0005879]; ciliary basal body [GO:0036064]; ciliary base [GO:0097546]; cytoplasmic microtubule [GO:0005881]; nucleus [GO:0005634]; sperm flagellum [GO:0036126] calcium-dependent protein binding [GO:0048306]; microtubule binding [GO:0008017] 0.97 -5.0329 EWIAHSEKLPRK 0 0 0 9.47557 0 0 0 0 0 0 0 0 0 0 0 0 0 9.79367 0 0 0 0 0 0 0 0 0 Q96E52 OMA1_HUMAN "Metalloendopeptidase OMA1, mitochondrial (EC 3.4.24.-) (Metalloprotease-related protein 1) (MPRP-1) (Overlapping with the m-AAA protease 1 homolog)" OMA1 MPRP1 Homo sapiens (Human) cristae formation [GO:0042407]; diet induced thermogenesis [GO:0002024]; energy homeostasis [GO:0097009]; glucose metabolic process [GO:0006006]; HRI-mediated signaling [GO:0140468]; integrated stress response signaling [GO:0140467]; lipid metabolic process [GO:0006629]; mitochondrial protein processing [GO:0034982]; mitochondrial respiratory chain complex assembly [GO:0033108]; negative regulation of mitochondrial fusion [GO:0010637]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cold-induced thermogenesis [GO:0120162]; protein autoprocessing [GO:0016540]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; regulation of apoptotic process [GO:0042981]; regulation of cristae formation [GO:1903850]; zymogen activation [GO:0031638] mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966] lipid binding [GO:0008289]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222] 0.59405 0.44758 EMCNCPPLSNPDPR 0 0 0 8.94122 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7363 0 0 Q96EA4 SPDLY_HUMAN Protein Spindly (hSpindly) (Arsenite-related gene 1 protein) (Coiled-coil domain-containing protein 99) (Rhabdomyosarcoma antigen MU-RMS-40.4A) (Spindle apparatus coiled-coil domain-containing protein 1) SPDL1 CCDC99 Homo sapiens (Human) cell division [GO:0051301]; cell migration [GO:0016477]; establishment of mitotic spindle orientation [GO:0000132]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly checkpoint signaling [GO:0007094]; protein localization to kinetochore [GO:0034501] cytosol [GO:0005829]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; outer kinetochore [GO:0000940]; spindle pole [GO:0000922] enzyme binding [GO:0019899]; kinetochore binding [GO:0043515] 0.9614 -2.594 ELLSCKSEELR 10.97 0 0 8.9939 0 0 0 0 0 8.56499 0 0 0 0 0 0 0 0 0 0 0 0 9.129 0 0 0 0 Q96EB6 SIR1_HUMAN NAD-dependent protein deacetylase sirtuin-1 (hSIRT1) (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-1) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (hSIR2) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)] SIRT1 SIR2L1 Homo sapiens (Human) "angiogenesis [GO:0001525]; behavioral response to starvation [GO:0042595]; cellular response to glucose starvation [GO:0042149]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; chromatin organization [GO:0006325]; circadian regulation of gene expression [GO:0032922]; DNA damage response [GO:0006974]; DNA methylation-dependent heterochromatin formation [GO:0006346]; DNA synthesis involved in DNA repair [GO:0000731]; energy homeostasis [GO:0097009]; fatty acid homeostasis [GO:0055089]; heterochromatin formation [GO:0031507]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; intracellular glucose homeostasis [GO:0001678]; intracellular triglyceride homeostasis [GO:0035356]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; leptin-mediated signaling pathway [GO:0033210]; macrophage differentiation [GO:0030225]; maintenance of nucleus location [GO:0051658]; muscle organ development [GO:0007517]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of attachment of mitotic spindle microtubules to kinetochore [GO:1902424]; negative regulation of cAMP-dependent protein kinase activity [GO:2000480]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; negative regulation of cellular response to testosterone stimulus [GO:2000655]; negative regulation of cellular senescence [GO:2000773]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of helicase activity [GO:0051097]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of peptidyl-lysine acetylation [GO:2000757]; negative regulation of phosphorylation [GO:0042326]; negative regulation of prostaglandin biosynthetic process [GO:0031393]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of triglyceride biosynthetic process [GO:0010868]; ovulation from ovarian follicle [GO:0001542]; peptidyl-lysine acetylation [GO:0018394]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of DNA repair [GO:0045739]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of histone methylation [GO:0031062]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of macroautophagy [GO:0016239]; positive regulation of macrophage apoptotic process [GO:2000111]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell differentiation [GO:0051152]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deacetylation [GO:0006476]; protein depropionylation [GO:0106230]; protein destabilization [GO:0031648]; protein ubiquitination [GO:0016567]; pyrimidine dimer repair by nucleotide-excision repair [GO:0000720]; rDNA heterochromatin formation [GO:0000183]; regulation of apoptotic process [GO:0042981]; regulation of bile acid biosynthetic process [GO:0070857]; regulation of brown fat cell differentiation [GO:0090335]; regulation of cell population proliferation [GO:0042127]; regulation of cellular response to heat [GO:1900034]; regulation of centrosome duplication [GO:0010824]; regulation of endodeoxyribonuclease activity [GO:0032071]; regulation of glucose metabolic process [GO:0010906]; regulation of lipid storage [GO:0010883]; regulation of mitotic cell cycle [GO:0007346]; regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035358]; regulation of protein serine/threonine kinase activity [GO:0071900]; regulation of smooth muscle cell apoptotic process [GO:0034391]; regulation of transcription by glucose [GO:0046015]; response to hydrogen peroxide [GO:0042542]; response to insulin [GO:0032868]; response to leptin [GO:0044321]; response to oxidative stress [GO:0006979]; single strand break repair [GO:0000012]; spermatogenesis [GO:0007283]; stress-induced premature senescence [GO:0090400]; transforming growth factor beta receptor signaling pathway [GO:0007179]; triglyceride mobilization [GO:0006642]; UV-damage excision repair [GO:0070914]; white fat cell differentiation [GO:0050872]" chromatin [GO:0000785]; chromatin silencing complex [GO:0005677]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; eNoSc complex [GO:0061773]; euchromatin [GO:0000791]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear inner membrane [GO:0005637]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; rDNA heterochromatin [GO:0033553] bHLH transcription factor binding [GO:0043425]; deacetylase activity [GO:0019213]; DNA-binding transcription factor binding [GO:0140297]; enzyme activator activity [GO:0008047]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; histone binding [GO:0042393]; histone deacetylase activity [GO:0004407]; HLH domain binding [GO:0043398]; identical protein binding [GO:0042802]; keratin filament binding [GO:1990254]; metal ion binding [GO:0046872]; mitogen-activated protein kinase binding [GO:0051019]; molecular function activator activity [GO:0140677]; molecular function inhibitor activity [GO:0140678]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent histone decrotonylase activity [GO:0160012]; NAD-dependent histone H3K9 deacetylase activity [GO:0046969]; NAD-dependent protein deacetylase activity [GO:0034979]; nuclear receptor binding [GO:0016922]; p53 binding [GO:0002039]; phosphatase inhibitor activity [GO:0019212]; promoter-specific chromatin binding [GO:1990841]; protein lysine deacetylase activity [GO:0033558]; protein-propionyllysine depropionylase activity [GO:0106231]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription regulator activator activity [GO:0140537] 0.96721 -2.8603 DPRPFFKFAK 0 0 0 0 0 0 0 0 0 0 8.58991 0 0 0 0 8.95012 10.1444 0 0 0 0 0 0 0 0 0 0 Q96ED9 HOOK2_HUMAN Protein Hook homolog 2 (h-hook2) (hHK2) HOOK2 Homo sapiens (Human) cytoplasmic microtubule organization [GO:0031122]; cytoskeleton-dependent intracellular transport [GO:0030705]; early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; lysosome organization [GO:0007040]; protein localization to perinuclear region of cytoplasm [GO:1905719]; protein transport [GO:0015031] centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; FHF complex [GO:0070695]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; trans-Golgi network [GO:0005802] dynein light intermediate chain binding [GO:0051959]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017] 0.55646 0.55593 IRHLEMDFEKSR 0 0 0 0 0 0 0 0 8.58353 0 0 0 9.63742 8.70915 0 9.04824 0 0 0 0 0 0 0 0 0 0 0 Q96EG1 ARSG_HUMAN Arylsulfatase G (ASG) (EC 3.1.6.1) (N-sulfoglucosamine-3-sulfatase) (EC 3.1.6.15) ARSG KIAA1001 UNQ839/PRO1777 Homo sapiens (Human) sulfur compound metabolic process [GO:0006790] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; lysosome [GO:0005764] arylsulfatase activity [GO:0004065]; metal ion binding [GO:0046872]; N-sulfoglucosamine-3-sulfatase activity [GO:0033889] 0.87074 0.028397 WHLGHHGSYHPNFR 0 9.3384 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96EG3 ZN837_HUMAN Zinc finger protein 837 ZNF837 Homo sapiens (Human) nucleus [GO:0005634] identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96935 -4.7623 EAPAQKAGQGGLPK 0 0 0 0 0 0 0 0 0 0 0 0 12.0592 0 0 0 0 0 9.02934 0 0 0 0 0 0 0 0 Q96EH3 MASU1_HUMAN Mitochondrial assembly of ribosomal large subunit protein 1 MALSU1 C7orf30 Homo sapiens (Human) negative regulation of mitochondrial translation [GO:0070130]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of translation [GO:0017148]; ribosomal large subunit biogenesis [GO:0042273] cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] mitochondrial large ribosomal subunit binding [GO:0140978]; ribosomal large subunit binding [GO:0043023] 0.95473 -1.5016 VARLLAPLMWR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5887 0 0 0 0 0 0 0 0 0 0 Q96EK5 KBP_HUMAN KIF-binding protein (KIF1-binding protein) (Kinesin family binding protein) KIFBP KBP KIAA1279 KIF1BP Homo sapiens (Human) central nervous system projection neuron axonogenesis [GO:0021952]; in utero embryonic development [GO:0001701]; microtubule cytoskeleton organization [GO:0000226]; mitochondrial transport [GO:0006839]; neuron projection maintenance [GO:1990535] cytoskeleton [GO:0005856]; mitochondrion [GO:0005739] kinesin binding [GO:0019894] 0.96949 -5.4963 ALLEEVK 0 0 0 0 0 0 0 0 0 0 0 8.88332 0 0 9.20249 0 0 0 0 0 0 0 0 0 0 0 0 Q96EK6 GNA1_HUMAN Glucosamine 6-phosphate N-acetyltransferase (EC 2.3.1.4) (Phosphoglucosamine acetylase) (Phosphoglucosamine transacetylase) GNPNAT1 GNA1 Homo sapiens (Human) UDP-N-acetylglucosamine biosynthetic process [GO:0006048] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139] glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; identical protein binding [GO:0042802]; monosaccharide binding [GO:0048029] 0.47189 0.62857 ITLECLPQNVGFYKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.511 Q96EK9 KTI12_HUMAN Protein KTI12 homolog KTI12 SBBI81 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357]; tRNA modification [GO:0006400] ATP binding [GO:0005524] 0.922 -1.0982 NVSVSWRPR 0 0 0 0 0 0 0 0 0 10.2347 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96EL2 RT24_HUMAN "Small ribosomal subunit protein uS3m (28S ribosomal protein S24, mitochondrial) (MRP-S24) (S24mt) (bMRP-47) (bMRP47)" MRPS24 HSPC335 Homo sapiens (Human) mitochondrial translation [GO:0032543] mitochondrial inner membrane [GO:0005743]; mitochondrial small ribosomal subunit [GO:0005763] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.95416 -1.534 LHLQTVPSKVVYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.49987 9.50281 0 0 0 0 0 0 0 0 0 Q96EN8 MOCOS_HUMAN Molybdenum cofactor sulfurase (MCS) (MOS) (MoCo sulfurase) (hMCS) (EC 2.8.1.9) (Molybdenum cofactor sulfurtransferase) MOCOS Homo sapiens (Human) Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdopterin cofactor biosynthetic process [GO:0032324]; molybdopterin cofactor metabolic process [GO:0043545] cytosol [GO:0005829] lyase activity [GO:0016829]; Mo-molybdopterin cofactor sulfurase activity [GO:0008265]; molybdenum cofactor sulfurtransferase activity [GO:0102867]; molybdenum ion binding [GO:0030151]; pyridoxal phosphate binding [GO:0030170] 0.92436 -1.0644 IFGFPTGLGALLVHNR 0 0 9.64279 0 0 0 0 0 0 0 0 0 0 10.0856 0 0 10.2331 0 0 0 0 0 0 0 0 9.50902 0 Q96EN9 REX1B_HUMAN Required for excision 1-B domain-containing protein REX1BD C19orf60 Homo sapiens (Human) 0.80221 0.24104 SLQELEQTR 0 0 0 0 0 0 0 0 0 0 0 0 0 8.99387 0 0 0 0 0 0 0 0 10.1803 0 0 0 0 Q96EP0 RNF31_HUMAN E3 ubiquitin-protein ligase RNF31 (EC 2.3.2.31) (HOIL-1-interacting protein) (HOIP) (RING finger protein 31) (RING-type E3 ubiquitin transferase RNF31) (Zinc in-between-RING-finger ubiquitin-associated domain protein) RNF31 ZIBRA Homo sapiens (Human) CD40 signaling pathway [GO:0023035]; defense response to bacterium [GO:0042742]; negative regulation of necroptotic process [GO:0060546]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of xenophagy [GO:1904417]; protein linear polyubiquitination [GO:0097039]; protein polyubiquitination [GO:0000209]; T cell receptor signaling pathway [GO:0050852] CD40 receptor complex [GO:0035631]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; LUBAC complex [GO:0071797] identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; K63-linked polyubiquitin modification-dependent protein binding [GO:0070530]; linear polyubiquitin binding [GO:1990450]; metal ion binding [GO:0046872]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842] 0.96909 -3.4732 ALTELQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.20782 0 0 0 0 10.3701 0 Q96EP1 CHFR_HUMAN E3 ubiquitin-protein ligase CHFR (EC 2.3.2.27) (Checkpoint with forkhead and RING finger domains protein) (RING finger protein 196) (RING-type E3 ubiquitin transferase CHFR) CHFR RNF196 Homo sapiens (Human) cell division [GO:0051301]; meiotic spindle checkpoint signaling [GO:0044779]; mitotic G2/M transition checkpoint [GO:0044818]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] nucleus [GO:0005634]; PML body [GO:0016605] metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.95742 -1.6537 CPVERICK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1933 0 0 0 0 0 0 0 11.8194 Q96EQ0 SGTB_HUMAN Small glutamine-rich tetratricopeptide repeat-containing protein beta (Beta-SGT) (Small glutamine-rich protein with tetratricopeptide repeats 2) SGTB SGT2 Homo sapiens (Human) post-translational protein targeting to endoplasmic reticulum membrane [GO:0006620] membrane [GO:0016020]; TRC complex [GO:0072380] molecular adaptor activity [GO:0060090] 0.78825 0.25094 LGHYTDAIK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.824 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96ER3 SAAL1_HUMAN Protein SAAL1 (Synoviocyte proliferation-associated in collagen-induced arthritis protein 1) (SPACIA1) SAAL1 Homo sapiens (Human) positive regulation of synoviocyte proliferation [GO:1901647] nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.96568 -2.3657 EVDKALADDLEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.646 Q96ES7 SGF29_HUMAN SAGA-associated factor 29 (Coiled-coil domain-containing protein 101) (SAGA complex-associated factor 29) SGF29 CCDC101 Homo sapiens (Human) establishment of protein localization to chromatin [GO:0071169]; histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of DNA repair [GO:0006282]; regulation of DNA-templated transcription [GO:0006355]; regulation of embryonic development [GO:0045995]; regulation of histone deacetylation [GO:0031063]; regulation of RNA splicing [GO:0043484]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tubulin deacetylation [GO:0090043]; transcription initiation-coupled chromatin remodeling [GO:0045815] ATAC complex [GO:0140672]; mitotic spindle [GO:0072686]; nucleus [GO:0005634]; SAGA complex [GO:0000124]; SAGA-type complex [GO:0070461] methylated histone binding [GO:0035064] 0.92311 -1.165 ISPYYRTK 0 0 0 0 0 0 0 0 10.1561 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96EU6 RRP36_HUMAN Ribosomal RNA processing protein 36 homolog RRP36 C6orf153 HSPC253 Homo sapiens (Human) "cleavage involved in rRNA processing [GO:0000469]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364]" 90S preribosome [GO:0030686]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] RNA binding [GO:0003723] 0.92278 -1.0571 AGAGAGAGAR 0 10.2267 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.77837 0 0 0 0 9.23384 Q96EU7 C1GLC_HUMAN "C1GALT1-specific chaperone 1 (C38H2-like protein 1) (C38H2-L1) (Core 1 beta1,3-galactosyltransferase 2) (C1Gal-T2) (C1GalT2) (Core 1 beta3-Gal-T2) (Core 1 beta3-galactosyltransferase-specific molecular chaperone)" C1GALT1C1 COSMC HSPC067 MSTP143 UNQ273/PRO310 Homo sapiens (Human) "O-glycan processing, core 1 [GO:0016267]; platelet activation [GO:0030168]; platelet morphogenesis [GO:0036344]; protein O-linked glycosylation [GO:0006493]" extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139] glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity [GO:0016263] 0.95507 -1.5672 AEFFSSENVK 0 0 0 0 0 0 0 0 0 11.7891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96EV2 RBM33_HUMAN RNA-binding protein 33 (Proline-rich protein 8) (RNA-binding motif protein 33) RBM33 PRR8 Homo sapiens (Human) RNA binding [GO:0003723] 0.9693 -3.9686 DIKEESDEEEEDDEESGRLR 0 0 0 0 0 0 0 0 0 0 0 9.5127 0 0 10.7847 0 0 0 0 0 0 0 0 0 0 0 0 Q96EV8 DTBP1_HUMAN Dysbindin (Biogenesis of lysosome-related organelles complex 1 subunit 8) (BLOC-1 subunit 8) (Dysbindin-1) (Dystrobrevin-binding protein 1) (Hermansky-Pudlak syndrome 7 protein) (HPS7 protein) DTNBP1 BLOC1S8 My031 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; blood coagulation [GO:0007596]; brain development [GO:0007420]; dendrite morphogenesis [GO:0048813]; melanosome organization [GO:0032438]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of neuron death [GO:1901215]; negative regulation of protein binding [GO:0032091]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; platelet dense granule organization [GO:0060155]; positive regulation of gene expression [GO:0010628]; positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization [GO:0061646]; positive regulation of neurotransmitter secretion [GO:0001956]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; regulation of dopamine receptor signaling pathway [GO:0060159]; regulation of dopamine secretion [GO:0014059]; regulation of JUN kinase activity [GO:0043506]; regulation of synaptic vesicle exocytosis [GO:2000300]; retina development in camera-type eye [GO:0060041] axon [GO:0030424]; axon cytoplasm [GO:1904115]; BLOC-1 complex [GO:0031083]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; melanosome membrane [GO:0033162]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; Schaffer collateral - CA1 synapse [GO:0098685]; synaptic vesicle membrane [GO:0030672] 0.92314 -1.1509 ELETFKAELDAEHAQK 0 0 0 0 0 0 0 0 0 0 9.45781 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96EW2 HBAP1_HUMAN HSPB1-associated protein 1 (27 kDa heat shock protein-associated protein 1) (Protein associated with small stress protein 1) HSPBAP1 PASS1 Homo sapiens (Human) cytoplasm [GO:0005737] 2-oxoglutarate-dependent dioxygenase activity [GO:0016706] 0.95439 -1.5101 DFVDKDGEHFGK 0 0 0 0 0 0 0 0 0 0 9.08555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96EY7 PTCD3_HUMAN "Small ribosomal subunit protein mS39 (28S ribosomal protein S39, mitochondrial) (MRP-S39) (Pentatricopeptide repeat domain-containing protein 3, mitochondrial) (Transformation-related gene 15 protein) (TRG-15)" PTCD3 MRPS39 TRG15 Homo sapiens (Human) mitochondrial translation [GO:0032543]; regulation of translation [GO:0006417] cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial small ribosomal subunit [GO:0005763]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; rRNA binding [GO:0019843] 0.91972 -0.90128 AGHQFGVTWR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1387 0 0 0 0 0 0 0 0 Q96EY8 MMAB_HUMAN Corrinoid adenosyltransferase MMAB (EC 2.5.1.-) (ATP:co(I)rrinoid adenosyltransferase MMAB) (Methylmalonic aciduria type B protein) MMAB Homo sapiens (Human) cobalamin metabolic process [GO:0009235] mitochondrial matrix [GO:0005759] "ATP binding [GO:0005524]; cobalamin binding [GO:0031419]; corrinoid adenosyltransferase activity [GO:0008817]; transferase activity, transferring alkyl or aryl (other than methyl) groups [GO:0016765]" 0.95837 -1.6771 AVCRRAER 0 0 0 0 0 0 0 12.2226 0 0 10.6041 0 10.1425 0 8.59656 0 10.7764 0 0 9.92367 0 0 10.0677 10.5827 0 0 0 Q96F07 CYFP2_HUMAN Cytoplasmic FMR1-interacting protein 2 (p53-inducible protein 121) CYFIP2 KIAA1168 PIR121 Homo sapiens (Human) activation of cysteine-type endopeptidase activity [GO:0097202]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; cell morphogenesis [GO:0000902]; cell projection assembly [GO:0030031]; cell-cell adhesion [GO:0098609]; dendrite extension [GO:0097484]; positive regulation of neurotrophin TRK receptor signaling pathway [GO:0051388]; positive regulation of proteolysis [GO:0045862]; regulation of actin filament polymerization [GO:0030833] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; SCAR complex [GO:0031209]; synapse [GO:0045202] small GTPase binding [GO:0031267] 0.96132 -2.5735 ALFHPTGGTQGRR 0 0 0 0 0 0 0 10.5 0 0 0 0 10.8065 0 0 0 0 10.4931 0 0 0 0 0 0 0 0 0 Q96F10 SAT2_HUMAN Thialysine N-epsilon-acetyltransferase (EC 2.3.1.-) (Diamine acetyltransferase 2) (EC 2.3.1.57) (Spermidine/spermine N(1)-acetyltransferase 2) (SSAT-2) SAT2 SSAT2 Homo sapiens (Human) nor-spermidine metabolic process [GO:0046204]; putrescine acetylation [GO:0032920]; spermidine acetylation [GO:0032918]; spermine acetylation [GO:0032919] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062] diamine N-acetyltransferase activity [GO:0004145]; identical protein binding [GO:0042802]; N-acetyltransferase activity [GO:0008080] 0.86457 0.078005 ADGFGDNPFYHCLVAEILPAPGK 0 0 0 0 0 0 13.8166 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96F15 GIMA5_HUMAN GTPase IMAP family member 5 (Immune-associated nucleotide-binding protein 5) (Immunity-associated nucleotide 4-like 1 protein) (Immunity-associated nucleotide 5 protein) (IAN-5) (hIAN5) (Immunity-associated protein 3) GIMAP5 IAN4L1 IAN5 IMAP3 Homo sapiens (Human) lysosomal membrane [GO:0005765]; multivesicular body membrane [GO:0032585] GTP binding [GO:0005525] 0.96906 -3.9742 DLVRECERR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.8305 0 0 0 0 0 0 0 0 0 Q96F46 I17RA_HUMAN Interleukin-17 receptor A (IL-17 receptor A) (IL-17RA) (CDw217) (CD antigen CD217) IL17RA IL17R Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; defense response to fungus [GO:0050832]; fibroblast activation [GO:0072537]; granulocyte chemotaxis [GO:0071621]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-17-mediated signaling pathway [GO:0097400]; interleukin-17A-mediated signaling pathway [GO:0038173]; positive regulation of chemokine (C-X-C motif) ligand 1 production [GO:2000340]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of interleukin-5 production [GO:0032754]; positive regulation of interleukin-6 production [GO:0032755]; protein catabolic process [GO:0030163]; response to virus [GO:0009615]; T-helper 17 type immune response [GO:0072538] extracellular region [GO:0005576]; plasma membrane [GO:0005886] interleukin-17 receptor activity [GO:0030368]; signaling receptor binding [GO:0005102] 0.45973 0.63816 HQVQIQPFFSSCLNDCLR 0 0 0 0 0 9.74589 0 0 0 0 0 0 0 0 0 0 0 0 9.80726 0 0 0 0 0 0 0 0 Q96F81 DISP1_HUMAN Protein dispatched homolog 1 DISP1 DISPA Homo sapiens (Human) determination of left/right symmetry [GO:0007368]; diaphragm development [GO:0060539]; dorsal/ventral pattern formation [GO:0009953]; embryonic pattern specification [GO:0009880]; patched ligand maturation [GO:0007225]; peptide transport [GO:0015833]; protein homotrimerization [GO:0070207]; regulation of protein secretion [GO:0050708]; smoothened signaling pathway [GO:0007224] basolateral plasma membrane [GO:0016323]; membrane [GO:0016020] peptide transmembrane transporter activity [GO:1904680] 0.89205 -0.50674 ATLANYPFK 0 0 0 0 0 0 0 0 10.6199 0 0 0 0 11.1677 0 0 0 9.95918 0 0 0 0 9.80499 0 0 0 0 Q96FA3 PELI1_HUMAN E3 ubiquitin-protein ligase pellino homolog 1 (Pellino-1) (EC 2.3.2.27) (Pellino-related intracellular-signaling molecule) (RING-type E3 ubiquitin transferase pellino homolog 1) PELI1 PRISM Homo sapiens (Human) negative regulation of necroptotic process [GO:0060546]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cytokine production [GO:0001819]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of toll-like receptor 3 signaling pathway [GO:0034141]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; regulation of necroptotic process [GO:0060544]; regulation of Toll signaling pathway [GO:0008592]; response to dsRNA [GO:0043331]; response to lipopolysaccharide [GO:0032496]; T cell proliferation [GO:0042098] cytosol [GO:0005829]; nucleus [GO:0005634] ubiquitin protein ligase activity [GO:0061630]; ubiquitin-ubiquitin ligase activity [GO:0034450] 0.88076 0.013452 DQHSISYTLSR 0 0 0 0 0 0 0 0 0 9.08815 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96FA7 ZB10P_HUMAN Putative protein ZBED10P (ZBED6 C-terminal-like protein) (zinc finger BED-type containing 10 pseudogene) ZBED10P C7orf29 ZBED6CL Homo sapiens (Human) 0.54402 0.5779 YLWENETVGAQDDPLAYWEKK 0 0 0 0 11.5887 0 0 0 12.1377 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96FB5 MT25B_HUMAN Methyltransferase-like protein 25B (Protein RRNAD1) (Ribosomal RNA adenine dimethylase domain-containing protein 1) METTL25B C1orf66 RRNAD1 CGI-41 Homo sapiens (Human) membrane [GO:0016020] "rRNA (adenine-N6,N6-)-dimethyltransferase activity [GO:0000179]" 0.95867 -1.6933 IEEYVQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.91106 0 0 0 0 0 0 0 0 0 0 0 Q96FE5 LIGO1_HUMAN Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 (Leucine-rich repeat and immunoglobulin domain-containing protein 1) (Leucine-rich repeat neuronal protein 1) (Leucine-rich repeat neuronal protein 6A) LINGO1 LERN1 LRRN6A UNQ201/PRO227 Homo sapiens (Human) extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] epidermal growth factor receptor binding [GO:0005154] 0.89753 -0.67066 AQQVFVDEGHTVQFVCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.22323 0 0 0 0 0 0 0 0 0 0 Q96FF7 MISP3_HUMAN Uncharacterized protein MISP3 (MISP family member 3) MISP3 Homo sapiens (Human) 0.96542 -2.3709 AGAQMQRDIER 0 0 0 0 0 0 0 0 0 0 9.91825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96FF9 CDCA5_HUMAN Sororin (Cell division cycle-associated protein 5) (p35) CDCA5 Homo sapiens (Human) cell division [GO:0051301]; double-strand break repair [GO:0006302]; mitotic cell cycle [GO:0000278]; mitotic chromosome condensation [GO:0007076]; mitotic metaphase plate congression [GO:0007080]; mitotic sister chromatid cohesion [GO:0007064]; positive regulation of exit from mitosis [GO:0031536] "chromatin [GO:0000785]; chromosome [GO:0005694]; chromosome, centromeric region [GO:0000775]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]" chromatin binding [GO:0003682]; protein-containing complex binding [GO:0044877] 0.88194 -0.30062 ENEPPGRELTK 0 0 0 0 0 0 0 0 0 13.8017 14.1274 14.2576 12.1936 12.0749 12.4062 12.8864 12.8456 0 0 0 0 0 0 0 0 0 0 Q96FI4 NEIL1_HUMAN Endonuclease 8-like 1 (EC 3.2.2.-) (EC 4.2.99.18) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (Endonuclease VIII-like 1) (FPG1) (Nei homolog 1) (NEH1) (Nei-like protein 1) NEIL1 Homo sapiens (Human) "base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; depyrimidination [GO:0045008]; negative regulation of nuclease activity [GO:0032074]; response to oxidative stress [GO:0006979]" chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; microtubule organizing center [GO:0005815]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA N-glycosylase activity [GO:0019104]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; zinc ion binding [GO:0008270]" 0.92202 -1.0859 ALVFGGCVEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.51909 0 0 0 0 Q96FJ0 STALP_HUMAN AMSH-like protease (AMSH-LP) (EC 3.4.19.-) (STAM-binding protein-like 1) STAMBPL1 AMSHLP KIAA1373 Homo sapiens (Human) cellular response to leucine [GO:0071233]; positive regulation of TORC1 signaling [GO:1904263]; protein deubiquitination [GO:0016579]; protein K63-linked deubiquitination [GO:0070536] cytosol [GO:0005829]; endosome [GO:0005768]; membrane [GO:0016020] K63-linked deubiquitinase activity [GO:0061578]; metal ion binding [GO:0046872]; metal-dependent deubiquitinase activity [GO:0140492]; molecular function inhibitor activity [GO:0140678] 0.95486 -1.5663 LKEIAFPR 0 0 0 0 0 0 0 10.9946 0 10.3237 10.2748 0 0 0 0 0 0 0 0 0 0 9.41022 0 0 0 0 0 Q96FK6 WDR89_HUMAN WD repeat-containing protein 89 WDR89 C14orf150 MSTP050 Homo sapiens (Human) corpus callosum development [GO:0022038]; ventricular system development [GO:0021591] 0.96355 -2.1341 VHSNDSYKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3531 0 0 0 0 0 Q96FL8 S47A1_HUMAN Multidrug and toxin extrusion protein 1 (MATE-1) (hMATE-1) (Solute carrier family 47 member 1) SLC47A1 MATE1 Homo sapiens (Human) amino acid import across plasma membrane [GO:0089718]; L-alpha-amino acid transmembrane transport [GO:1902475]; L-arginine import across plasma membrane [GO:0097638]; organic cation transport [GO:0015695]; putrescine transport [GO:0015847]; transmembrane transport [GO:0055085]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport [GO:0042908] apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; membrane [GO:0016020]; plasma membrane [GO:0005886]; vesicle [GO:0031982] amide transmembrane transporter activity [GO:0042887]; antiporter activity [GO:0015297]; L-amino acid transmembrane transporter activity [GO:0015179]; L-arginine transmembrane transporter activity [GO:0061459]; organic cation transmembrane transporter activity [GO:0015101]; polyspecific organic cation:proton antiporter activity [GO:0140968]; putrescine transmembrane transporter activity [GO:0015489]; thiamine transmembrane transporter activity [GO:0015234]; xenobiotic transmembrane transporter activity [GO:0042910] 0.91782 -0.87214 KACQQAQVHANLK 0 0 0 0 0 0 0 0 0 0 8.91112 0 0 0 0 0 0 0 0 0 0 0 0 10.1124 0 0 0 Q96FN5 KIF12_HUMAN Kinesin-like protein KIF12 KIF12 Homo sapiens (Human) microtubule-based movement [GO:0007018] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; kinesin complex [GO:0005871]; microtubule [GO:0005874] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777] 0.92387 -1.0544 KQSHIPFR 0 0 0 0 0 0 0 0 0 0 0 10.7353 0 0 0 9.97871 0 0 0 0 0 0 0 0 9.69732 0 0 Q96FN9 DTD2_HUMAN D-aminoacyl-tRNA deacylase 2 (EC 3.1.1.96) (Animalia-specific tRNA deacylase) (ATD) (D-tyrosyl-tRNA(Tyr) deacylase 2) (L-alanyl-tRNA deacylase) DTD2 C14orf126 Homo sapiens (Human) aminoacyl-tRNA metabolism involved in translational fidelity [GO:0106074]; tRNA metabolic process [GO:0006399] cytoplasm [GO:0005737] Ala-tRNA(Thr) hydrolase activity [GO:0106105]; D-tyrosyl-tRNA(Tyr) deacylase activity [GO:0051500]; tRNA binding [GO:0000049] 0.85111 0.16099 LDTNGPFTHLIEF 0 0 0 0 10.0204 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96FS4 SIPA1_HUMAN Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase-activating protein Spa-1) (p130 SPA-1) SIPA1 SPA1 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; adaptive immune response [GO:0002250]; cellular response to water deprivation [GO:0042631]; cytoskeleton organization [GO:0007010]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell polarity [GO:0090162]; intracellular signal transduction [GO:0035556]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; transport vesicle [GO:0030133] GTPase activator activity [GO:0005096] 0.69633 0.37597 ALNGEQAAGHAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.516 0 0 0 0 0 0 9.08635 0 Q96FT9 IFT43_HUMAN Intraflagellar transport protein 43 homolog IFT43 C14orf179 Homo sapiens (Human) cilium assembly [GO:0060271]; intraciliary retrograde transport [GO:0035721] centriolar satellite [GO:0034451]; centriole [GO:0005814]; ciliary tip [GO:0097542]; cilium [GO:0005929]; cytoplasm [GO:0005737]; intraciliary transport particle A [GO:0030991]; microtubule cytoskeleton [GO:0015630] 0.9067 -0.73211 KASEEIEDFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0121 0 Q96FV0 LRC46_HUMAN Leucine-rich repeat-containing protein 46 LRRC46 Homo sapiens (Human) 0.95991 -1.9433 EGITTIR 0 0 0 0 11.3698 0 0 0 0 9.85364 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96FV9 THOC1_HUMAN THO complex subunit 1 (Tho1) (Nuclear matrix protein p84) (p84N5) (hTREX84) THOC1 HPR1 Homo sapiens (Human) "apoptotic process [GO:0006915]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; negative regulation of DNA damage checkpoint [GO:2000002]; negative regulation of isotype switching to IgA isotypes [GO:0048297]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; regulation of DNA recombination [GO:0000018]; regulation of DNA-templated transcription elongation [GO:0032784]; replication fork processing [GO:0031297]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]; signal transduction [GO:0007165]; viral mRNA export from host cell nucleus [GO:0046784]" cytoplasm [GO:0005737]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; THO complex [GO:0000347]; THO complex part of transcription export complex [GO:0000445]; transcription export complex [GO:0000346] DNA binding [GO:0003677]; RNA binding [GO:0003723] 0.94796 -1.3608 HILLQYLILFQYLKGQVK 9.74143 0 9.69829 0 0 0 0 0 0 0 0 0 11.0183 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96FX7 TRM61_HUMAN tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A (EC 2.1.1.220) (mRNA methyladenosine-N(1)-methyltransferase catalytic subunit TRMT61A) (EC 2.1.1.-) (tRNA(m1A58)-methyltransferase subunit TRMT61A) (tRNA(m1A58)MTase subunit TRMT61A) TRMT61A C14orf172 TRM61 Homo sapiens (Human) mRNA methylation [GO:0080009]; tRNA methylation [GO:0030488] nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tRNA (m1A) methyltransferase complex [GO:0031515] mRNA (adenine-N1-)-methyltransferase activity [GO:0061953]; tRNA (adenine-N1-)-methyltransferase activity [GO:0016429] 0.13251 1.0605 HSVDLIGRPFGSK 11.995 11.0641 10.9299 8.8828 9.26155 9.17988 9.50754 11.3375 0 11.6048 11.7524 11.6964 0 0 0 10.0211 10.684 0 0 0 0 0 0 10.478 0 0 0 Q96FZ2 HMCES_HUMAN Abasic site processing protein HMCES (Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein) (ES cell-specific 5hmC-binding protein) (Peptidase HMCES) (EC 3.4.-.-) (SRAP domain-containing protein 1) HMCES C3orf37 DC12 SRAPD1 Homo sapiens (Human) DNA damage response [GO:0006974]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; positive regulation of isotype switching [GO:0045830]; protein-DNA covalent cross-linking [GO:0018142]; proteolysis [GO:0006508] replication fork [GO:0005657] peptidase activity [GO:0008233]; single-stranded DNA binding [GO:0003697] 0.96189 -2.0407 DPDKYCPSYNK 0 0 0 0 0 8.67009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96G01 BICD1_HUMAN Protein bicaudal D homolog 1 (Bic-D 1) BICD1 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; intracellular mRNA localization [GO:0008298]; microtubule anchoring at microtubule organizing center [GO:0072393]; minus-end-directed organelle transport along microtubule [GO:0072385]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900737]; positive regulation of protein localization to centrosome [GO:1904781]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein localization to organelle [GO:0033365]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of proteinase activated receptor activity [GO:1900276]; RNA processing [GO:0006396]; stress granule assembly [GO:0034063]; viral process [GO:0016032] centrosome [GO:0005813]; cytoplasmic vesicle [GO:0031410]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; secretory vesicle [GO:0099503]; trans-Golgi network [GO:0005802] cytoskeletal anchor activity [GO:0008093]; dynactin binding [GO:0034452]; dynein complex binding [GO:0070840]; dynein intermediate chain binding [GO:0045505]; protein kinase binding [GO:0019901]; proteinase activated receptor binding [GO:0031871]; small GTPase binding [GO:0031267]; structural constituent of cytoskeleton [GO:0005200] 0.9545 -1.5222 AELDGEK 8.81121 0 0 0 10.6797 0 14.0905 14.3154 0 0 0 0 0 0 0 13.6435 0 0 0 0 0 0 0 0 0 0 0 Q96G03 PGM2_HUMAN Phosphopentomutase (EC 5.4.2.7) (Glucose phosphomutase 2) (Phosphodeoxyribomutase) (Phosphoglucomutase-2) (EC 5.4.2.2) PGM2 MSTP006 Homo sapiens (Human) glucose metabolic process [GO:0006006]; glycogen catabolic process [GO:0005980]; purine ribonucleoside salvage [GO:0006166] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774] magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphopentomutase activity [GO:0008973] 0.95438 -1.5091 NNYPKACGK 8.53496 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96G21 IMP4_HUMAN U3 small nucleolar ribonucleoprotein protein IMP4 (U3 snoRNP protein IMP4) (Brix domain-containing protein 4) IMP4 BXDC4 Homo sapiens (Human) maturation of SSU-rRNA [GO:0030490]; ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364] fibrillar center [GO:0001650]; Mpp10 complex [GO:0034457]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; preribosome [GO:0030684]; small-subunit processome [GO:0032040] rRNA primary transcript binding [GO:0042134]; snoRNA binding [GO:0030515] 0.89974 -0.6081 VSDILRYLFPVPK 0 0 0 0 0 0 9.55323 0 0 0 0 0 0 0 0 0 0 12.1648 0 0 0 0 0 0 0 0 0 Q96G23 CERS2_HUMAN Ceramide synthase 2 (CerS2) (LAG1 longevity assurance homolog 2) (SP260) (Sphingosine N-acyltransferase CERS2) (EC 2.3.1.24) (Tumor metastasis-suppressor gene 1 protein) (Very-long-chain ceramide synthase CERS2) (EC 2.3.1.297) CERS2 LASS2 TMSG1 Homo sapiens (Human) ceramide biosynthetic process [GO:0046513]; negative regulation of axon regeneration [GO:0048681]; negative regulation of Schwann cell migration [GO:1900148]; negative regulation of Schwann cell proliferation involved in axon regeneration [GO:1905045]; regulation of lipid metabolic process [GO:0019216]; sphingolipid biosynthetic process [GO:0030148] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] DNA binding [GO:0003677]; sphingosine N-acyltransferase activity [GO:0050291] 0.91577 -0.80549 LWLPVNLTWADLEDRDGR 0 0 0 0 0 0 0 0 0 0 0 0 9.82426 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96G46 DUS3L_HUMAN tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like (EC 1.3.1.89) (mRNA-dihydrouridine synthase DUS3L) (EC 1.3.1.-) (tRNA-dihydrouridine synthase 3-like) DUS3L Homo sapiens (Human) mRNA processing [GO:0006397]; regulation of translation [GO:0006417]; tRNA dihydrouridine synthesis [GO:0002943] flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]; mRNA dihydrouridine synthase activity [GO:0106414]; RNA binding [GO:0003723]; tRNA dihydrouridine synthase activity [GO:0017150] 0.87034 0.0426 DFTNYGLEHWGSDTQGVEKTR 0 0 0 0 0 0 0 0 0 0 0 9.56499 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96G74 OTUD5_HUMAN OTU domain-containing protein 5 (EC 3.4.19.12) (Deubiquitinating enzyme A) (DUBA) OTUD5 Homo sapiens (Human) negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of type I interferon production [GO:0032480]; neural crest cell differentiation [GO:0014033]; positive regulation of TORC1 signaling [GO:1904263]; positive regulation of TORC2 signaling [GO:1904515]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; response to lipopolysaccharide [GO:0032496] cytosol [GO:0005829]; nucleus [GO:0005634] cysteine-type deubiquitinase activity [GO:0004843]; deubiquitinase activity [GO:0101005]; K48-linked deubiquitinase activity [GO:1990380]; K63-linked deubiquitinase activity [GO:0061578] 0.11849 1.0871 KPPPPDADPANEPPPPGPMPPAPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1161 9.90257 0 0 9.3224 0 0 0 0 0 Q96GA3 LTV1_HUMAN Protein LTV1 homolog LTV1 C6orf93 Homo sapiens (Human) ribosomal small subunit biogenesis [GO:0042274]; ribosomal small subunit export from nucleus [GO:0000056] "cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; preribosome, small subunit precursor [GO:0030688]" 0.96293 -2.5231 EPSGPSELIPSSTFSAHNRREEK 0 9.73256 0 0 0 0 11.625 0 0 0 0 12.3265 11.1755 11.4428 0 11.3989 0 0 0 0 0 0 0 0 0 0 0 Q96GA7 SDSL_HUMAN Serine dehydratase-like (L-serine deaminase) (L-serine dehydratase/L-threonine deaminase) (L-threonine dehydratase) (TDH) (EC 4.3.1.19) (Serine dehydratase 2) (SDH 2) (EC 4.3.1.17) SDSL Homo sapiens (Human) isoleucine biosynthetic process [GO:0009097]; L-serine catabolic process [GO:0006565]; lipid metabolic process [GO:0006629]; threonine catabolic process [GO:0006567] cytosol [GO:0005829] identical protein binding [GO:0042802]; L-serine ammonia-lyase activity [GO:0003941]; L-threonine ammonia-lyase activity [GO:0004794]; pyridoxal phosphate binding [GO:0030170] 0.88461 -0.29616 SLGAKTVAAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.67495 0 0 0 0 0 0 0 0 0 0 0 Q96GC5 RM48_HUMAN "Large ribosomal subunit protein mL48 (39S ribosomal protein L48, mitochondrial) (L48mt) (MRP-L48)" MRPL48 CGI-118 HSPC290 Homo sapiens (Human) mitochondrial translation [GO:0032543] mitochondrial inner membrane [GO:0005743]; mitochondrial large ribosomal subunit [GO:0005762]; mitochondrial ribosome [GO:0005761]; mitochondrion [GO:0005739] 0.9629 -2.6647 LSVKEHTEEDFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1814 0 0 0 0 0 0 0 0 Q96GC6 ZN274_HUMAN Neurotrophin receptor-interacting factor homolog (Zinc finger protein 274) (Zinc finger protein HFB101) (Zinc finger protein with KRAB and SCAN domains 19) (Zinc finger protein zfp2) (Zf2) ZNF274 ZKSCAN19 SP2114 Homo sapiens (Human) chromatin remodeling [GO:0006338]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] cytoplasm [GO:0005737]; nucleolus [GO:0005730] "chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.87804 0.019626 CGKAFTQSSHLIGHQR 0 0 0 0 0 0 11.4114 9.90614 0 0 0 0 0 0 9.22509 0 10.4519 0 0 0 0 0 0 0 0 0 0 Q96GD3 SCMH1_HUMAN Polycomb protein SCMH1 (Sex comb on midleg homolog 1) SCMH1 Homo sapiens (Human) heterochromatin formation [GO:0031507]; negative regulation of DNA-templated transcription [GO:0045892] nucleoplasm [GO:0005654] 0.88331 -0.069704 TVLEHQPGQRGRKPGK 0 0 0 0 0 0 9.49027 0 0 0 0 11.4107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96GD4 AURKB_HUMAN Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B) AURKB AIK2 AIM1 AIRK2 ARK2 STK1 STK12 STK5 Homo sapiens (Human) abscission [GO:0009838]; aging [GO:0007568]; attachment of spindle microtubules to kinetochore [GO:0008608]; cell cycle G2/M phase transition [GO:0044839]; cell population proliferation [GO:0008283]; cellular response to UV [GO:0034644]; cleavage furrow formation [GO:0036089]; histone modification [GO:0016570]; mitotic cell cycle [GO:0000278]; mitotic cytokinesis [GO:0000281]; mitotic cytokinesis checkpoint signaling [GO:0044878]; mitotic spindle midzone assembly [GO:0051256]; mitotic spindle organization [GO:0007052]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of cytokinesis [GO:0032466]; negative regulation of innate immune response [GO:0045824]; negative regulation of protein binding [GO:0032091]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of attachment of mitotic spindle microtubules to kinetochore [GO:1902425]; positive regulation of cytokinesis [GO:0032467]; positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore [GO:1905116]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; positive regulation of mitotic cytokinesis [GO:1903490]; positive regulation of mitotic sister chromatid segregation [GO:0062033]; positive regulation of mitotic sister chromatid separation [GO:1901970]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; post-translational protein modification [GO:0043687]; protein autophosphorylation [GO:0046777]; protein localization to kinetochore [GO:0034501]; protein phosphorylation [GO:0006468]; regulation of chromosome segregation [GO:0051983]; regulation of cytokinesis [GO:0032465]; regulation of signal transduction by p53 class mediator [GO:1901796]; spindle organization [GO:0007051] "chromocenter [GO:0010369]; chromosome passenger complex [GO:0032133]; condensed chromosome, centromeric region [GO:0000779]; cytosol [GO:0005829]; kinetochore [GO:0000776]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; mitotic spindle midzone [GO:1990023]; mitotic spindle pole [GO:0097431]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819]; spindle microtubule [GO:0005876]; spindle midzone [GO:0051233]; spindle pole centrosome [GO:0031616]" ATP binding [GO:0005524]; histone H3S28 kinase activity [GO:0044022]; kinase binding [GO:0019900]; molecular function inhibitor activity [GO:0140678]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712] 0.8721 0.050331 LYNYFYDR 0 0 0 0 0 0 0 0 0 0 0 0 8.8839 0 0 0 0 0 0 0 9.20982 0 0 0 0 0 0 Q96GE4 CEP95_HUMAN Centrosomal protein of 95 kDa (Cep95) (Coiled-coil domain-containing protein 45) CEP95 CCDC45 CEP45 Homo sapiens (Human) centrosome [GO:0005813]; cytoplasm [GO:0005737]; spindle pole [GO:0000922] 0.96936 -3.5428 DLRNYAKEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.88437 0 10.6391 0 10.6415 10.4642 10.4466 0 0 0 0 Q96GE6 CALL4_HUMAN Calmodulin-like protein 4 (Serologically defined breast cancer antigen NY-BR-20) CALML4 Homo sapiens (Human) calcium ion binding [GO:0005509]; enzyme regulator activity [GO:0030234] 0.9149 -0.82996 ATDLMVAMR 0 0 0 0 0 0 0 9.24852 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96GF1 RN185_HUMAN E3 ubiquitin-protein ligase RNF185 (EC 2.3.2.27) (RING finger protein 185) RNF185 Homo sapiens (Human) autophagy [GO:0006914]; defense response to virus [GO:0051607]; endoplasmic reticulum mannose trimming [GO:1904380]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; innate immune response [GO:0045087]; positive regulation of ERAD pathway [GO:1904294]; positive regulation of innate immune response [GO:0045089]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein autoubiquitination [GO:0051865]; protein K27-linked ubiquitination [GO:0044314]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum quality control compartment [GO:0044322]; mitochondrial outer membrane [GO:0005741] enzyme activator activity [GO:0008047]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-like protein conjugating enzyme binding [GO:0044390] 0.826 0.21412 VIPLYGR 0 0 0 0 0 0 0 0 9.8464 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96GI7 FA89A_HUMAN Protein FAM89A FAM89A C1orf153 Homo sapiens (Human) 0.29285 0.81792 GGPGGGGAR 0 0 8.2717 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.45914 0 0 0 0 0 0 0 0 0 Q96GJ1 TRM2B_HUMAN tRNA (uracil-5-)-methyltransferase homolog B (EC 2.1.1.35) (TRM2 homolog B) (rRNA (uracil-5-)-methyltransferase TRMT2B) (EC 2.1.1.-) TRMT2B CXorf34 Homo sapiens (Human) mitochondrion [GO:0005739] rRNA (uridine-C5-)-methyltransferase activity [GO:0070041]; S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity [GO:0030697] 0.96968 -3.9442 GPDGNPK 0 0 0 0 0 0 0 0 8.14614 8.65274 8.88634 9.65331 0 0 0 0 0 0 0 0 0 0 0 9.53504 0 0 0 Q96GK7 FAH2A_HUMAN Fumarylacetoacetate hydrolase domain-containing protein 2A (EC 3.-.-.-) FAHD2A CGI-105 Homo sapiens (Human) hydrolase activity [GO:0016787]; metal ion binding [GO:0046872] 0.85055 0.10829 TMTQFLEQGEATLSVAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3749 0 0 0 Q96GM8 TOE1_HUMAN Target of EGR1 protein 1 TOE1 Homo sapiens (Human) "RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; snRNA 3'-end processing [GO:0034472]" Cajal body [GO:0015030]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] 3'-5'-RNA exonuclease activity [GO:0000175]; metal ion binding [GO:0046872]; poly(A)-specific ribonuclease activity [GO:0004535]; snRNA binding [GO:0017069] 0.9642 -2.4346 AVCHAARTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.8588 0 0 0 0 0 0 0 0 0 0 0 Q96GN5 CDA7L_HUMAN Cell division cycle-associated 7-like protein (Protein JPO2) (Transcription factor RAM2) CDCA7L HR1 JPO2 R1 Homo sapiens (Human) positive regulation of cell population proliferation [GO:0008284]; regulation of DNA-templated transcription [GO:0006355] cytosol [GO:0005829]; fibrillar center [GO:0001650]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.96727 -2.8023 TIGGKCREYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4338 0 0 9.7132 0 0 0 0 0 0 0 0 Q96GP6 SREC2_HUMAN Scavenger receptor class F member 2 (SRECRP-1) (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) SCARF2 SREC2 SREPCR Homo sapiens (Human) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157] focal adhesion [GO:0005925]; membrane [GO:0016020] scavenger receptor activity [GO:0005044] 0.82036 0.21827 APPATETPGPEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.516 0 0 0 0 0 0 0 0 Q96GQ5 RUSF1_HUMAN RUS family member 1 RUSF1 C16orf58 Homo sapiens (Human) membrane [GO:0016020] 0.95272 -1.4934 GLQDAGWKTEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.53041 0 0 Q96GQ7 DDX27_HUMAN Probable ATP-dependent RNA helicase DDX27 (EC 3.6.4.13) (DEAD box protein 27) DDX27 cPERP-F RHLP HSPC259 PP3241 Homo sapiens (Human) rRNA processing [GO:0006364] chromosome [GO:0005694]; nucleolus [GO:0005730] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.92599 -1.2097 AGRAGRSVSLVGEDER 16.4181 10.6663 9.58575 0 0 15.4799 16.2628 0 0 15.687 0 16.0025 0 15.9615 16.0153 16.0045 15.9329 15.503 0 0 0 12.4202 12.2782 0 0 0 0 Q96GR2 ACBG1_HUMAN Long-chain-fatty-acid--CoA ligase ACSBG1 (EC 6.2.1.3) (Acyl-CoA synthetase bubblegum family member 1) (hBG1) (hsBG) (hsBGM) (Lipidosin) ACSBG1 BGM KIAA0631 LPD Homo sapiens (Human) long-chain fatty acid biosynthetic process [GO:0042759]; long-chain fatty acid metabolic process [GO:0001676]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; myelination [GO:0042552]; ovarian follicle atresia [GO:0001552]; response to glucocorticoid [GO:0051384]; very long-chain fatty acid metabolic process [GO:0000038] cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; CoA-ligase activity [GO:0016405]; long-chain fatty acid-CoA ligase activity [GO:0004467]; very long-chain fatty acid-CoA ligase activity [GO:0031957] 0.86993 0.052159 LDADGFLYITGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.70982 0 0 0 Q96GU1 PAGE5_HUMAN P antigen family member 5 (PAGE-5) (Cancer/testis antigen 16.1) (CT16.1) (G antigen family E member 1) (Prostate-associated gene 5 protein) PAGE5 GAGEE1 Homo sapiens (Human) 0.89838 -0.62554 IEDAPGDGPDVREGTLPTFDPTK 0 11.0034 10.8234 0 0 0 10.9462 10.9481 0 9.68774 9.72166 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96GV9 MACIR_HUMAN Macrophage immunometabolism regulator MACIR C5orf30 Homo sapiens (Human) cilium assembly [GO:0060271]; epithelial cell migration [GO:0010631]; fibroblast migration [GO:0010761]; inflammatory response [GO:0006954]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of inflammatory response [GO:0050728]; protein transport [GO:0015031] ciliary transition zone [GO:0035869]; cytoplasm [GO:0005737] 0.65486 0.3955 MPSSGDK 9.19409 8.75766 0 0 0 0 0 0 9.26348 0 0 9.23611 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96GW9 SYMM_HUMAN "Methionine--tRNA ligase, mitochondrial (EC 6.1.1.10) (Methionyl-tRNA synthetase 2) (Mitochondrial methionyl-tRNA synthetase) (MtMetRS)" MARS2 Homo sapiens (Human) methionyl-tRNA aminoacylation [GO:0006431]; tRNA aminoacylation for protein translation [GO:0006418] mitochondrial matrix [GO:0005759] ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825] 0.93829 -1.2943 ALEAVSSCVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0843 0 0 0 10.2074 0 0 0 0 0 0 0 0 Q96GX1 TECT2_HUMAN Tectonic-2 TCTN2 C12orf38 TECT2 Homo sapiens (Human) cilium assembly [GO:0060271]; protein localization to ciliary transition zone [GO:1904491]; smoothened signaling pathway [GO:0007224] ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; MKS complex [GO:0036038] 0.85009 0.1089 AEINAHQKGIMTQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2984 0 0 Q96GX5 GWL_HUMAN Serine/threonine-protein kinase greatwall (GW) (GWL) (hGWL) (EC 2.7.11.1) (Microtubule-associated serine/threonine-protein kinase-like) (MAST-L) MASTL GW GWL THC2 Homo sapiens (Human) cell division [GO:0051301]; DNA damage response [GO:0006974]; female meiosis II [GO:0007147]; G2/M transition of mitotic cell cycle [GO:0000086]; intracellular signal transduction [GO:0035556]; mitotic cell cycle [GO:0000278]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; regulation of cell cycle [GO:0051726] centrosome [GO:0005813]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; kinase activity [GO:0016301]; protein phosphatase 2A binding [GO:0051721]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96153 -2.5603 DPTAGSK 0 0 0 0 0 0 0 0 0 0 0 10.4291 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96GX8 CP074_HUMAN Uncharacterized protein C16orf74 C16orf74 Homo sapiens (Human) 0.95171 -1.4229 MGLKMSCLK 0 0 0 0 0 0 0 10.314 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96GY3 LIN37_HUMAN Protein lin-37 homolog (Antolefinin) LIN37 MSTP064 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] Myb complex [GO:0031523]; nucleoplasm [GO:0005654]; transcription repressor complex [GO:0017053] 0.96245 -2.4487 ILREMYER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.16538 0 0 0 Q96H12 MSD3_HUMAN Myb/SANT-like DNA-binding domain-containing protein 3 MSANTD3 C9orf30 L8 Homo sapiens (Human) 0.96377 -2.6447 ITANKNYR 0 0 0 0 0 0 10.486 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96H20 SNF8_HUMAN Vacuolar-sorting protein SNF8 (ELL-associated protein of 30 kDa) (ESCRT-II complex subunit VPS22) (hVps22) SNF8 EAP30 Homo sapiens (Human) early endosome to late endosome transport [GO:0045022]; endocytic recycling [GO:0032456]; localization [GO:0051179]; macroautophagy [GO:0016236]; membrane fission [GO:0090148]; multivesicular body assembly [GO:0036258]; multivesicular body sorting pathway [GO:0071985]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of gene expression [GO:0010628]; positive regulation of protein catabolic process [GO:0045732]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; regulation of protein catabolic process [GO:0042176]; regulation of protein complex stability [GO:0061635]; regulation of transcription by RNA polymerase II [GO:0006357] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; ESCRT II complex [GO:0000814]; extracellular exosome [GO:0070062]; late endosome membrane [GO:0031902]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; transcription regulator complex [GO:0005667] channel regulator activity [GO:0016247]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803] 0.78834 0.24712 ASLKWETERAR 0 0 0 0 0 0 0 0 0 0 0 8.72891 0 0 0 0 0 0 0 0 0 0 0 0 0 12.7892 0 Q96H22 CENPN_HUMAN Centromere protein N (CENP-N) (Interphase centromere complex protein 32) CENPN C16orf60 ICEN32 BM-309 Homo sapiens (Human) CENP-A containing chromatin assembly [GO:0034080]; chromosome segregation [GO:0007059] cytosol [GO:0005829]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654] 0.8697 0.053545 VQRITQETFGDYPQPQLEFAQYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.7912 0 0 0 0 0 0 0 Q96H35 RBM18_HUMAN Probable RNA-binding protein 18 (RNA-binding motif protein 18) RBM18 Homo sapiens (Human) cytosol [GO:0005829]; intercellular bridge [GO:0045171]; nucleoplasm [GO:0005654] RNA binding [GO:0003723] 0.72077 0.36253 QFDFLFHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.87166 10.1381 0 0 0 0 0 Q96H40 ZN486_HUMAN Zinc finger protein 486 (KRAB domain only protein 2) ZNF486 KRBO2 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] extracellular exosome [GO:0070062]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.89864 -0.57409 CKECGKAFNWSSDLNK 0 0 10.9743 0 13.2897 0 0 11.4309 11.2687 13.7246 0 0 0 0 0 0 0 0 0 0 0 9.50458 0 0 0 0 0 Q96H55 MYO19_HUMAN Unconventional myosin-XIX (Myosin head domain-containing protein 1) MYO19 MYOHD1 Homo sapiens (Human) actin filament organization [GO:0007015]; mitochondrion migration along actin filament [GO:0034642]; mitocytosis [GO:0160040]; regulation of cytokinesis [GO:0032465]; regulation of mitochondrial fission [GO:0090140]; vesicle transport along actin filament [GO:0030050] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; myosin complex [GO:0016459]; vesicle [GO:0031982] actin binding [GO:0003779]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; myosin light chain binding [GO:0032027]; plus-end directed microfilament motor activity [GO:0060002] 0.16694 0.97519 LQQHFVAHYLR 0 0 11.2279 0 0 0 0 0 0 0 9.4641 0 0 0 0 0 0 0 0 0 10.2952 0 0 0 0 0 0 Q96H72 S39AD_HUMAN Zinc transporter ZIP13 (LIV-1 subfamily of ZIP zinc transporter 9) (LZT-Hs9) (Solute carrier family 39 member 13) (Zrt- and Irt-like protein 13) (ZIP-13) SLC39A13 ZIP13 Homo sapiens (Human) brown fat cell differentiation [GO:0050873]; connective tissue development [GO:0061448]; intracellular zinc ion homeostasis [GO:0006882]; zinc ion transmembrane transport [GO:0071577]; zinc ion transport [GO:0006829] cytoplasmic vesicle membrane [GO:0030659]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471] protein homodimerization activity [GO:0042803]; zinc ion transmembrane transporter activity [GO:0005385] 0.88332 -0.26995 AGFDRWSAAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.0724 0 0 0 0 Q96H79 ZCCHL_HUMAN Zinc finger CCCH-type antiviral protein 1-like ZC3HAV1L C7orf39 Homo sapiens (Human) cytosol [GO:0005829] 0.30239 0.80726 AEPTVCSFLTK 0 0 0 0 0 0 0 0 0 9.46773 9.1249 9.08353 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96H86 ZN764_HUMAN Zinc finger protein 764 ZNF764 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.94775 -1.3582 FSQSSALYQHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.45914 0 0 0 0 0 0 0 0 0 0 0 Q96HA1 P121A_HUMAN Nuclear envelope pore membrane protein POM 121 (Nuclear envelope pore membrane protein POM 121A) (Nucleoporin Nup121) (Pore membrane protein of 121 kDa) POM121 KIAA0618 NUP121 POM121A Homo sapiens (Human) mRNA transport [GO:0051028]; nucleocytoplasmic transport [GO:0006913]; protein import into nucleus [GO:0006606]; RNA export from nucleus [GO:0006405] endoplasmic reticulum membrane [GO:0005789]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654] nuclear localization sequence binding [GO:0008139]; structural constituent of nuclear pore [GO:0017056] 0.16443 0.99315 AADTTPR 0 0 0 0 0 0 0 0 0 0 0 8.22689 0 0 0 9.82428 0 0 0 0 0 0 0 0 0 0 0 Q96HA4 CA159_HUMAN Uncharacterized protein C1orf159 C1orf159 UNQ2998/PRO9739 Homo sapiens (Human) membrane [GO:0016020] 0.84123 0.18107 SSGTPGRPHPGAPR 0 0 0 0 0 0 0 10.3002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96HA9 PX11C_HUMAN Peroxisomal membrane protein 11C (Peroxin-11C) (Peroxisomal biogenesis factor 11C) (Protein PEX11 homolog gamma) (PEX11-gamma) PEX11G PEX11C Homo sapiens (Human) peroxisome fission [GO:0016559]; regulation of peroxisome size [GO:0044375] peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991] 0.84168 0.18272 VLHVDSSR 0 0 0 0 0 0 0 0 0 0 0 0 0 12.0508 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96HD1 CREL1_HUMAN Protein disulfide isomerase CRELD1 (EC 5.3.4.1) (Cysteine-rich with EGF-like domain protein 1) CRELD1 CIRRIN UNQ188/PRO214 Homo sapiens (Human) cardiac septum development [GO:0003279]; endocardial cushion development [GO:0003197] collagen-containing extracellular matrix [GO:0062023]; membrane [GO:0016020] calcium ion binding [GO:0005509]; protein disulfide isomerase activity [GO:0003756] 0.84808 0.1282 LLELSEELVESWWFHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6592 0 0 Q96HE7 ERO1A_HUMAN ERO1-like protein alpha (ERO1-L) (ERO1-L-alpha) (EC 1.8.4.-) (Endoplasmic oxidoreductin-1-like protein) (Endoplasmic reticulum oxidoreductase alpha) (Oxidoreductin-1-L-alpha) ERO1A ERO1L UNQ434/PRO865 Homo sapiens (Human) brown fat cell differentiation [GO:0050873]; cell redox homeostasis [GO:0045454]; cellular response to hypoxia [GO:0071456]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; extracellular matrix organization [GO:0030198]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; protein folding [GO:0006457]; protein folding in endoplasmic reticulum [GO:0034975]; protein maturation by protein folding [GO:0022417]; protein modification process [GO:0036211]; release of sequestered calcium ion into cytosol [GO:0051209]; response to endoplasmic reticulum stress [GO:0034976]; response to oxidative stress [GO:0006979]; response to temperature stimulus [GO:0009266] dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020] FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]; protein-disulfide reductase activity [GO:0015035]; thiol oxidase activity [GO:0016972] 0.89789 -0.67974 AVLQWTK 0 0 0 12.5268 0 9.4614 0 14.0448 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.67389 0 0 Q96HE8 TMM80_HUMAN Transmembrane protein 80 TMEM80 Homo sapiens (Human) non-motile cilium assembly [GO:1905515] ciliary transition zone [GO:0035869]; membrane [GO:0016020] 0.84283 0.15187 TSAPETR 10.0806 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96HF1 SFRP2_HUMAN Secreted frizzled-related protein 2 (FRP-2) (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) SFRP2 FRP2 SARP1 FKSG12 UNQ361/PRO697 Homo sapiens (Human) BMP signaling pathway [GO:0030509]; branching involved in blood vessel morphogenesis [GO:0001569]; canonical Wnt signaling pathway [GO:0060070]; cardiac left ventricle morphogenesis [GO:0003214]; cardiac muscle cell apoptotic process [GO:0010659]; cell-cell signaling [GO:0007267]; cellular response to extracellular stimulus [GO:0031668]; cellular response to X-ray [GO:0071481]; chondrocyte development [GO:0002063]; collagen fibril organization [GO:0030199]; convergent extension involved in axis elongation [GO:0060028]; digestive tract morphogenesis [GO:0048546]; embryonic digit morphogenesis [GO:0042733]; hematopoietic stem cell proliferation [GO:0071425]; male gonad development [GO:0008584]; mesodermal cell fate specification [GO:0007501]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of dermatome development [GO:0061185]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of mesodermal cell fate specification [GO:0042662]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of planar cell polarity pathway involved in axis elongation [GO:2000041]; negative regulation of Wnt signaling pathway [GO:0030178]; non-canonical Wnt signaling pathway [GO:0035567]; outflow tract morphogenesis [GO:0003151]; planar cell polarity pathway involved in axis elongation [GO:0003402]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endopeptidase activity [GO:0010950]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; regulation of midbrain dopaminergic neuron differentiation [GO:1904956]; regulation of neuron projection development [GO:0010975]; regulation of stem cell division [GO:2000035]; response to nutrient [GO:0007584]; response to xenobiotic stimulus [GO:0009410]; sclerotome development [GO:0061056]; stem cell fate specification [GO:0048866]; Wnt signaling pathway involved in somitogenesis [GO:0090244] collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615] endopeptidase activator activity [GO:0061133]; fibronectin binding [GO:0001968]; integrin binding [GO:0005178]; receptor ligand activity [GO:0048018]; Wnt-protein binding [GO:0017147] 0.88264 -0.11451 EITYINR 0 0 0 0 0 0 0 0 0 0 0 10.9155 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96HH4 TM169_HUMAN Transmembrane protein 169 TMEM169 Homo sapiens (Human) membrane [GO:0016020] 0.89701 -0.62907 ELQELTKPKESSR 0 0 11.7113 0 0 0 0 9.87808 0 0 0 0 0 0 0 0 11.1075 0 0 0 0 0 0 0 0 0 0 Q96HH6 TMM19_HUMAN Transmembrane protein 19 TMEM19 Homo sapiens (Human) membrane [GO:0016020] 0.95329 -1.4947 SSPRLITTWEK 0 0 0 0 0 0 0 0 0 12.2948 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96HH9 GRM2B_HUMAN GRAM domain-containing protein 2B (HCV NS3-transactivated protein 2) GRAMD2B GRAMD3 NS3TP2 Homo sapiens (Human) cytoplasmic microtubule [GO:0005881] identical protein binding [GO:0042802] 0.96394 -2.4373 IISLWSKSSFDGASLASDKNDCK 8.46573 0 12.676 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96HI0 SENP5_HUMAN Sentrin-specific protease 5 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP5) SENP5 FKSG45 Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; protein desumoylation [GO:0016926]; protein sumoylation [GO:0016925] nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] deSUMOylase activity [GO:0016929]; SUMO-specific endopeptidase activity [GO:0070139] 0.95925 -1.7306 ENGEGGSCSPFPSPEPK 0 0 0 0 0 0 0 0 0 9.6755 0 0 0 0 0 11.4678 0 0 0 0 9.69284 0 0 0 0 0 0 Q96HJ3 CCD34_HUMAN Coiled-coil domain-containing protein 34 (Renal carcinoma antigen NY-REN-41) CCDC34 RAMA3 L15 Homo sapiens (Human) spermatogenesis [GO:0007283] sperm midpiece [GO:0097225] 0.80237 0.23984 FQEWLENAK 0 8.98077 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96HJ9 FMC1_HUMAN "Protein FMC1 homolog (ATP synthase assembly factor FMC1, mitochondrial) (Formation of mitochondrial complex V assembly factor 1 homolog)" FMC1 C7orf55 HSPC268 Homo sapiens (Human) mitochondrial proton-transporting ATP synthase complex assembly [GO:0033615]; negative regulation of lipid catabolic process [GO:0050995]; regulation of type B pancreatic cell proliferation [GO:0061469] mitochondrion [GO:0005739] 0.95536 -1.557 AHRVTSEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5721 0 0 0 0 0 Q96HP0 DOCK6_HUMAN Dedicator of cytokinesis protein 6 DOCK6 KIAA1395 Homo sapiens (Human) positive regulation of GTPase activity [GO:0043547]; small GTPase mediated signal transduction [GO:0007264] cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471] guanyl-nucleotide exchange factor activity [GO:0005085] 0.8862 -0.33816 HHNKLRLCFK 0 10.2287 9.35405 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96HQ0 ZN419_HUMAN Zinc finger protein 419 ZNF419 ZNF419A Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.9599 -1.9246 FYSHKSNLIKHWR 0 0 0 0 0 0 0 0 0 10.6665 10.6927 9.64613 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96HR8 NAF1_HUMAN H/ACA ribonucleoprotein complex non-core subunit NAF1 (hNAF1) NAF1 Homo sapiens (Human) box H/ACA snoRNP assembly [GO:0000493]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of telomere maintenance via telomere lengthening [GO:1904358]; ribosome biogenesis [GO:0042254]; RNA stabilization [GO:0043489]; snoRNA guided rRNA pseudouridine synthesis [GO:0000454]; telomerase holoenzyme complex assembly [GO:1905323]; telomerase RNA stabilization [GO:0090669] cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; sno(s)RNA-containing ribonucleoprotein complex [GO:0005732] identical protein binding [GO:0042802]; RNA binding [GO:0003723]; telomerase RNA binding [GO:0070034] 0.90575 -0.72288 DFTQYIFTEKLK 0 0 0 8.68979 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96HS1 PGAM5_HUMAN "Serine/threonine-protein phosphatase PGAM5, mitochondrial (EC 3.1.3.16) (Bcl-XL-binding protein v68) (Phosphoglycerate mutase family member 5)" PGAM5 Homo sapiens (Human) macroautophagy [GO:0016236]; necroptotic process [GO:0070266]; negative regulation of cold-induced thermogenesis [GO:0120163]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of mitochondrial fission [GO:0090141] mitochondrial inner membrane [GO:0005743]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739] GTPase activator activity [GO:0005096]; myosin phosphatase activity [GO:0017018]; phosphatase activity [GO:0016791]; protein serine/threonine phosphatase activity [GO:0004722]; protein-containing complex binding [GO:0044877] 0.93993 -1.3015 DRTLTPLGR 0 0 0 0 0 0 0 9.14272 0 0 0 0 0 0 0 11.7033 0 0 0 0 0 0 0 0 0 0 0 Q96HU1 SGSM3_HUMAN Small G protein signaling modulator 3 (Merlin-associated protein) (RUN and TBC1 domain-containing protein 3) (Rab-GTPase-activating protein-like protein) (RabGAPLP) SGSM3 MAP RABGAPLP RUTBC3 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; cell cycle [GO:0007049]; plasma membrane to endosome transport [GO:0048227]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein catabolic process [GO:0045732]; Rap protein signal transduction [GO:0032486]; regulation of cell cycle [GO:0051726]; regulation of Rab protein signal transduction [GO:0032483] cytosol [GO:0005829]; gap junction [GO:0005921] GTPase activator activity [GO:0005096]; small GTPase binding [GO:0031267] 0.90116 -0.69472 GTLCPALK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.39457 0 0 9.40557 0 0 0 9.52718 0 0 Q96HW7 INT4_HUMAN Integrator complex subunit 4 (Int4) INTS4 MSTP093 Homo sapiens (Human) regulation of transcription elongation by RNA polymerase II [GO:0034243]; snRNA processing [GO:0016180] integrator complex [GO:0032039]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.95992 -1.8917 DAEGLAAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.18066 0 0 0 0 0 0 0 0 Q96HY7 DHTK1_HUMAN "2-oxoadipate dehydrogenase complex component E1 (E1a) (OADC-E1) (OADH-E1) (EC 1.2.4.-) (2-oxoadipate dehydrogenase, mitochondrial) (Alpha-ketoadipate dehydrogenase) (Alpha-KADH-E1) (Dehydrogenase E1 and transketolase domain-containing protein 1) (Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial)" DHTKD1 KIAA1630 Homo sapiens (Human) generation of precursor metabolites and energy [GO:0006091]; glycolytic process [GO:0006096]; hematopoietic progenitor cell differentiation [GO:0002244]; tricarboxylic acid cycle [GO:0006099] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] oxoglutarate dehydrogenase (succinyl-transferring) activity [GO:0004591]; thiamine pyrophosphate binding [GO:0030976] 0.96358 -2.2492 LAFEYQRQFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.8501 11.1359 Q96I13 ABHD8_HUMAN Protein ABHD8 (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 8) (Abhydrolase domain-containing protein 8) ABHD8 Homo sapiens (Human) extracellular exosome [GO:0070062] hydrolase activity [GO:0016787] 0.05383 1.3945 LAPGSAGSGSGSGSGGRR 0 0 0 0 0 0 0 0 0 0 0 9.7234 0 0 0 0 0 11.8442 0 0 0 11.9356 11.9226 11.8655 0 10.3334 0 Q96I24 FUBP3_HUMAN Far upstream element-binding protein 3 (FUSE-binding protein 3) FUBP3 FBP3 Homo sapiens (Human) DNA-templated transcription [GO:0006351]; intracellular mRNA localization [GO:0008298]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468] cytoplasm [GO:0005737]; dendritic shaft [GO:0043198]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; polysome [GO:0005844]; ribosome [GO:0005840] mRNA binding [GO:0003729]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697] 0.87758 0.021346 GVPQQIEVARQLIDEK 0 10.4067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.564 0 0 0 10.2341 0 0 0 0 0 0 Q96I25 SPF45_HUMAN Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17) RBM17 SPF45 Homo sapiens (Human) "alternative mRNA splicing, via spliceosome [GO:0000380]; mRNA cis splicing, via spliceosome [GO:0045292]" nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681] RNA binding [GO:0003723] 0.95074 -1.3838 AVVDLNGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.12975 0 0 0 0 Q96I34 PP16A_HUMAN Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase-targeting subunit 3) PPP1R16A MYPT3 Homo sapiens (Human) cytoplasm [GO:0005737]; plasma membrane [GO:0005886] enzyme inhibitor activity [GO:0004857]; myosin phosphatase regulator activity [GO:0017020] 0.95992 -1.8126 MAEHLELLAEMPMVGRMSTQER 11.175 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.68061 0 0 0 0 0 0 Q96I51 RCC1L_HUMAN RCC1-like G exchanging factor-like protein (RCC1-like) (Williams-Beuren syndrome chromosomal region 16 protein) RCC1L WBSCR16 Homo sapiens (Human) mitochondrial fusion [GO:0008053]; positive regulation of mitochondrial translation [GO:0070131] mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966] GTP binding [GO:0005525]; guanyl-nucleotide exchange factor activity [GO:0005085]; RNA binding [GO:0003723]; rRNA binding [GO:0019843] 0.85029 0.16017 ISSAACGYGFTLLSSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.67424 0 0 0 0 0 0 0 0 Q96I59 SYNM_HUMAN "Probable asparagine--tRNA ligase, mitochondrial (EC 6.1.1.22) (Asparaginyl-tRNA synthetase) (AsnRS)" NARS2 Homo sapiens (Human) asparaginyl-tRNA aminoacylation [GO:0006421] cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] asparagine-tRNA ligase activity [GO:0004816]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676] 0.88513 -0.21709 DALGAQNASGER 0 0 0 0 0 0 0 0 0 0 0 0 0 9.18225 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96I82 KAZD1_HUMAN Kazal-type serine protease inhibitor domain-containing protein 1 KAZALD1 FKSG28 FKSG40 UNQ2945/PRO21184 Homo sapiens (Human) cell differentiation [GO:0030154]; extracellular matrix organization [GO:0030198]; ossification [GO:0001503]; regulation of cell growth [GO:0001558]; regulation of signal transduction [GO:0009966] extracellular space [GO:0005615]; interstitial matrix [GO:0005614] insulin-like growth factor binding [GO:0005520] 0.87663 -0.0063206 LDTGGDLSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.28404 0 0 0 0 0 0 Q96IC2 REXO5_HUMAN RNA exonuclease 5 (EC 3.1.-.-) (Exonuclease NEF-sp) REXO5 44M2.3 Homo sapiens (Human) extracellular exosome [GO:0070062]; nucleolus [GO:0005730]; nucleus [GO:0005634] exonuclease activity [GO:0004527]; RNA binding [GO:0003723] 0.83242 0.20099 FYLEFGCLR 0 0 0 0 0 0 0 0 0 0 0 0 9.3323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96ID5 IGS21_HUMAN Immunoglobulin superfamily member 21 (IgSF21) IGSF21 Homo sapiens (Human) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; synapse maturation [GO:0060074] adherens junction [GO:0005912]; external side of plasma membrane [GO:0009897]; inhibitory synapse [GO:0060077]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734] 0.95936 -1.8388 ARVGDTVR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8257 0 0 0 11.2657 0 0 0 0 0 9.79251 0 0 0 Q96IF1 AJUBA_HUMAN LIM domain-containing protein ajuba AJUBA JUB Homo sapiens (Human) "calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell cycle [GO:0007049]; cytoskeleton organization [GO:0007010]; focal adhesion assembly [GO:0048041]; glycerophospholipid biosynthetic process [GO:0046474]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; lamellipodium assembly [GO:0030032]; miRNA-mediated gene silencing [GO:0035195]; negative regulation of hippo signaling [GO:0035331]; negative regulation of kinase activity [GO:0033673]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cellular biosynthetic process [GO:0031328]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; positive regulation of protein-containing complex assembly [GO:0031334]; protein localization [GO:0008104]; regulation of cell migration [GO:0030334]; regulation of cellular response to hypoxia [GO:1900037]; regulation of DNA-templated transcription [GO:0006355]; regulation of GTPase activity [GO:0043087]; response to hypoxia [GO:0001666]; wound healing, spreading of epidermal cells [GO:0035313]" adherens junction [GO:0005912]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; lamellipodium [GO:0030027]; microtubule organizing center [GO:0005815]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; plasma membrane [GO:0005886]; transcription regulator complex [GO:0005667] actin filament binding [GO:0051015]; alpha-catenin binding [GO:0045294]; chromatin binding [GO:0003682]; metal ion binding [GO:0046872]; transcription corepressor activity [GO:0003714] 0.87755 -0.004082 EQGSLDAER 0 0 0 0 0 0 0 0 0 0 8.77456 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96IG2 FXL20_HUMAN F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like) FBXL20 FBL2 Homo sapiens (Human) "behavioral fear response [GO:0001662]; regulation of protein catabolic process at presynapse, modulating synaptic transmission [GO:0099575]; regulation of synaptic vesicle exocytosis [GO:2000300]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]" cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; presynapse [GO:0098793]; SCF ubiquitin ligase complex [GO:0019005]; Schaffer collateral - CA1 synapse [GO:0098685] 0.81223 0.22212 NIEVLNLNGCTK 0 0 0 0 0 0 0 0 0 0 0 0 11.3066 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96II8 LRCH3_HUMAN DISP complex protein LRCH3 (Leucine-rich repeat and calponin homology domain-containing protein 3) LRCH3 Homo sapiens (Human) septin cytoskeleton organization [GO:0032185] cytoplasm [GO:0005737]; cytosol [GO:0005829] 0.95438 -1.5291 LDFSCNKITTIPVCYR 0 0 0 0 0 0 0 0 0 9.47861 0 0 0 0 0 0 0 0 0 9.73666 0 0 0 0 0 0 0 Q96IL0 COA8_HUMAN "Cytochrome c oxidase assembly factor 8 (COA8) (Apoptogenic protein 1, mitochondrial) (APOP-1)" COA8 APOP1 APOPT1 C14orf153 Homo sapiens (Human) intrinsic apoptotic signaling pathway [GO:0097193]; mitochondrial cytochrome c oxidase assembly [GO:0033617]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; positive regulation of cytochrome-c oxidase activity [GO:1904960]; protein stabilization [GO:0050821]; response to reactive oxygen species [GO:0000302] matrix side of mitochondrial inner membrane [GO:0099617]; mitochondrion [GO:0005739] 0.94953 -1.381 MLPCAAGARGRGAMVVLR 0 0 10.1183 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96IM9 DYDC2_HUMAN DPY30 domain-containing protein 2 DYDC2 Homo sapiens (Human) Set1C/COMPASS complex [GO:0048188] 0.43996 0.64784 CFGNCLAQALAEVAK 0 0 0 0 0 0 0 0 9.1535 11.8329 12.1646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96IR7 HPDL_HUMAN 4-hydroxyphenylpyruvate dioxygenase-like protein (HPD-like protein) (EC 1.13.-.-) (Glyoxalase domain-containing protein 1) HPDL GLOXD1 Homo sapiens (Human) aromatic amino acid metabolic process [GO:0009072] mitochondrion [GO:0005739] 4-hydroxyphenylpyruvate dioxygenase activity [GO:0003868]; metal ion binding [GO:0046872] 0.8218 0.21802 QDQVEQFLAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.941 0 0 0 0 Q96IS3 RAX2_HUMAN Retina and anterior neural fold homeobox protein 2 (Q50-type retinal homeobox protein) (Retina and anterior neural fold homeobox-like protein 1) RAX2 QRX RAXL1 Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; response to stimulus [GO:0050896]; visual perception [GO:0007601] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.9399 -1.3258 LLAKEHAQALDRAWPPA 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1813 0 0 0 0 0 0 0 0 Q96IT1 ZN496_HUMAN Zinc finger protein 496 (Zinc finger protein with KRAB and SCAN domains 17) ZNF496 ZKSCAN17 Homo sapiens (Human) positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.81815 0.21979 SFTQNYDLLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.13584 0 0 0 0 Q96IU2 ZBED3_HUMAN Zinc finger BED domain-containing protein 3 (Axin-interacting protein) ZBED3 Homo sapiens (Human) actin filament organization [GO:0007015]; endoplasmic reticulum localization [GO:0051643]; establishment of spindle localization [GO:0051293]; mitochondrion localization [GO:0051646]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of embryonic development [GO:0040019]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein stabilization [GO:0050821]; regulation of transcription by RNA polymerase II [GO:0006357]; response to glucose [GO:0009749]; response to insulin [GO:0032868]; Wnt signaling pathway [GO:0016055] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020] "DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]" 0.90232 -0.70203 EALQARLRDVSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.0018 0 0 0 0 0 0 0 0 0 0 Q96IV0 NGLY1_HUMAN Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (PNGase) (hPNGase) (EC 3.5.1.52) (N-glycanase 1) (Peptide:N-glycanase) NGLY1 PNG1 Homo sapiens (Human) ER-associated misfolded protein catabolic process [GO:0071712]; glycoprotein catabolic process [GO:0006516]; protein deglycosylation [GO:0006517]; protein folding [GO:0006457]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] metal ion binding [GO:0046872]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224] 0.95902 -1.7647 KSQEKLSR 0 0 0 0 0 0 0 0 0 0 0 9.08847 0 0 0 0 0 0 9.1603 0 0 0 0 0 0 0 0 Q96IW2 SHD_HUMAN SH2 domain-containing adapter protein D SHD Homo sapiens (Human) phosphotyrosine residue binding [GO:0001784] 0.87146 0.036776 QPWFHGPLNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.25574 0 0 0 Q96IX9 A26L1_HUMAN Putative ankyrin repeat domain-containing protein 26-like 1 (Ankyrin repeat domain-containing protein 36B pseudogene 1) ANKRD36BP1 ANKRD26L1 Homo sapiens (Human) 0.84948 0.12134 NHLMQDEIAR 0 0 0 0 14.7984 0 0 0 0 10.4089 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96IY4 CBPB2_HUMAN Carboxypeptidase B2 (EC 3.4.17.20) (Carboxypeptidase U) (CPU) (Plasma carboxypeptidase B) (pCPB) (Thrombin-activable fibrinolysis inhibitor) (TAFI) CPB2 Homo sapiens (Human) blood coagulation [GO:0007596]; cellular response to glucose stimulus [GO:0071333]; fibrinolysis [GO:0042730]; liver regeneration [GO:0097421]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of plasminogen activation [GO:0010757]; positive regulation of extracellular matrix constituent secretion [GO:0003331]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to xenobiotic stimulus [GO:0009410] extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615] metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270] 0.96931 -3.1999 HPDMLTK 0 0 0 0 0 0 0 0 0 0 0 9.14519 0 0 0 0 0 0 0 0 0 9.73495 0 0 0 0 0 Q96IZ0 PAWR_HUMAN PRKC apoptosis WT1 regulator protein (Prostate apoptosis response 4 protein) (Par-4) PAWR PAR4 Homo sapiens (Human) actin filament bundle assembly [GO:0051017]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of gene expression [GO:0010629]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of amyloid precursor protein biosynthetic process [GO:0042986]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cellular senescence [GO:2000774]; positive regulation of gene expression [GO:0010628]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300] actin cytoskeleton [GO:0015629]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886] actin binding [GO:0003779]; enzyme binding [GO:0019899]; leucine zipper domain binding [GO:0043522]; transcription corepressor activity [GO:0003714] 0.95101 -1.4196 LVRLMQDK 0 0 0 0 0 0 0 0 9.52978 0 0 0 0 8.94743 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96IZ2 ADTRP_HUMAN Androgen-dependent TFPI-regulating protein (Fatty acid esters of hydroxy fatty acids hydrolase ADTRP) (FAHFA hydrolase ADTRP) (EC 3.1.-.-) ADTRP C6orf105 Homo sapiens (Human) cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to oxidised low-density lipoprotein particle stimulus [GO:0140052]; cellular response to steroid hormone stimulus [GO:0071383]; long-chain fatty acid catabolic process [GO:0042758]; negative regulation of blood coagulation [GO:0030195]; negative regulation of extracellular matrix constituent secretion [GO:0003332]; negative regulation of leukocyte cell-cell adhesion [GO:1903038]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of lymphocyte migration [GO:2000402]; negative regulation of protein secretion [GO:0050709]; positive regulation of gene expression [GO:0010628]; positive regulation of protein phosphorylation [GO:0001934]; protein kinase B signaling [GO:0043491] caveola [GO:0005901]; cell surface [GO:0009986]; endomembrane system [GO:0012505]; membrane [GO:0016020] hydrolase activity [GO:0016787] 0.95314 -1.4973 ILANGARWK 0 0 0 0 0 0 0 0 0 0 10.5994 0 0 0 0 11.0793 0 0 0 0 0 0 0 0 0 0 0 Q96J01 THOC3_HUMAN THO complex subunit 3 (Tho3) (TEX1 homolog) (hTREX45) THOC3 Homo sapiens (Human) mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380]; viral mRNA export from host cell nucleus [GO:0046784] nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; THO complex part of transcription export complex [GO:0000445]; transcription export complex [GO:0000346] RNA binding [GO:0003723] 0.076321 1.2586 GENINICWSPDGQTIAVGNKDDVVTFIDAK 12.4726 12.6805 0 0 0 0 12.5478 0 12.6716 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96J02 ITCH_HUMAN E3 ubiquitin-protein ligase Itchy homolog (Itch) (EC 2.3.2.26) (Atrophin-1-interacting protein 4) (AIP4) (HECT-type E3 ubiquitin transferase Itchy homolog) (NFE2-associated polypeptide 1) (NAPP1) ITCH Homo sapiens (Human) "apoptotic process [GO:0006915]; CD4-positive, alpha-beta T cell proliferation [GO:0035739]; defense response to virus [GO:0051607]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of defense response to virus [GO:0050687]; negative regulation of JNK cascade [GO:0046329]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of type I interferon production [GO:0032480]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of receptor catabolic process [GO:2000646]; positive regulation of T cell anergy [GO:0002669]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K29-linked ubiquitination [GO:0035519]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]; receptor internalization [GO:0031623]; regulation of cell growth [GO:0001558]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of necroptotic process [GO:0060544]; regulation of protein deubiquitination [GO:0090085]; T cell anergy [GO:0002870]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral entry into host cell [GO:0046718]" cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] arrestin family protein binding [GO:1990763]; CXCR chemokine receptor binding [GO:0045236]; ligase activity [GO:0016874]; ribonucleoprotein complex binding [GO:0043021]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-like protein transferase activity [GO:0019787]; ubiquitin-protein transferase activity [GO:0004842] 0.95162 -1.43 ENWLPRSHTCFNRLDLPPYK 0 0 0 0 0 0 0 0 0 13.2187 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96J65 MRP9_HUMAN ATP-binding cassette sub-family C member 12 (Multidrug resistance-associated protein 9) ABCC12 MRP9 Homo sapiens (Human) transmembrane transport [GO:0055085] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] ABC-type transporter activity [GO:0140359]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626] 0.88904 -0.42333 ELMEERGRYAK 14.9905 14.8714 16.3227 0 0 0 14.7857 14.7833 14.7043 0 15.7401 14.2399 0 9.1482 0 9.92134 9.80382 0 0 0 9.85812 0 9.97441 0 0 0 0 Q96J66 MRP8_HUMAN ATP-binding cassette sub-family C member 11 (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 8) ABCC11 MRP8 Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; leukotriene transport [GO:0071716]; organic anion transport [GO:0015711]; purine nucleotide transport [GO:0015865]; transmembrane transport [GO:0055085]; xenobiotic transport [GO:0042908] apical plasma membrane [GO:0016324]; cytoplasmic vesicle membrane [GO:0030659]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774] ABC-type bile acid transporter activity [GO:0015432]; ABC-type glutathione S-conjugate transporter activity [GO:0015431]; ABC-type xenobiotic transporter activity [GO:0008559]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled inorganic anion transmembrane transporter activity [GO:0043225]; ATPase-coupled transmembrane transporter activity [GO:0042626]; organic anion transmembrane transporter activity [GO:0008514]; purine nucleotide transmembrane transporter activity [GO:0015216] 0.88296 -0.2665 GLNLSGGQKQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.666 0 Q96J77 TPD55_HUMAN Tumor protein D55 (hD55) (Testis development protein NYD-SP25) (Tumor protein D52-like 3) TPD52L3 Homo sapiens (Human) cytoplasm [GO:0005737] 0.96232 -2.0343 ELKTKLTK 0 0 0 0 0 0 10.5135 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96J84 KIRR1_HUMAN Kin of IRRE-like protein 1 (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1) KIRREL1 KIRREL NEPH1 Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cell-cell junction maintenance [GO:0045217]; glomerular filtration [GO:0003094]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of actin filament polymerization [GO:0030838]; renal protein absorption [GO:0097017] cell-cell junction [GO:0005911]; dendritic shaft [GO:0043198]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] cell adhesion molecule binding [GO:0050839]; myosin binding [GO:0017022] 0.89713 -0.6765 DPTNGYYNVR 0 0 0 9.7061 10.1537 10.0865 0 0 0 0 9.62086 8.76451 0 0 0 0 0 0 10.261 0 0 0 0 0 0 0 0 Q96J87 CELF6_HUMAN CUGBP Elav-like family member 6 (CELF-6) (Bruno-like protein 6) (CUG-BP- and ETR-3-like factor 6) (RNA-binding protein BRUNOL-6) CELF6 BRUNOL6 Homo sapiens (Human) "mRNA splice site selection [GO:0006376]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]" cytoplasm [GO:0005737]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] mRNA binding [GO:0003729]; RNA binding [GO:0003723] 0.88919 -0.44272 LTGLHKGCAFLTYCAR 9.5195 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9527 0 9.56929 0 0 0 0 0 0 0 0 0 Q96J92 WNK4_HUMAN Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase lysine-deficient 4) (Protein kinase with no lysine 4) WNK4 PRKWNK4 Homo sapiens (Human) activation of protein kinase activity [GO:0032147]; aldosterone secretion [GO:0035932]; calcium ion homeostasis [GO:0055074]; cellular response to xenobiotic stimulus [GO:0071466]; chloride transport [GO:0006821]; distal tubule morphogenesis [GO:0072156]; ERK1 and ERK2 cascade [GO:0070371]; gene expression [GO:0010467]; inflammatory response [GO:0006954]; intracellular chloride ion homeostasis [GO:0030644]; intracellular signal transduction [GO:0035556]; macrophage activation [GO:0042116]; monoatomic ion homeostasis [GO:0050801]; negative regulation of pancreatic juice secretion [GO:0090188]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of sodium ion transport [GO:0010766]; potassium ion transmembrane transport [GO:0071805]; protein kinase C signaling [GO:0070528]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; renal sodium ion absorption [GO:0070294]; renal sodium ion transport [GO:0003096]; response to dietary excess [GO:0002021]; signal transduction [GO:0007165]; sodium ion transmembrane transport [GO:0035725] bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; protein-containing complex [GO:0032991] ATP binding [GO:0005524]; chloride channel inhibitor activity [GO:0019869]; chloride ion binding [GO:0031404]; ion channel inhibitor activity [GO:0008200]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96764 -3.7093 GVHVELAEEDDGEKPGLK 0 0 0 0 0 0 0 0 11.8708 0 0 0 0 0 0 10.0816 0 0 0 0 0 0 10.5304 0 11.4411 0 0 Q96J94 PIWL1_HUMAN Piwi-like protein 1 (EC 3.1.26.-) PIWIL1 HIWI Homo sapiens (Human) meiotic cell cycle [GO:0051321]; negative regulation of transposition [GO:0010529]; piRNA processing [GO:0034587]; regulation of translation [GO:0006417]; RNA-mediated gene silencing [GO:0031047]; sperm DNA condensation [GO:0035092]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283] chromatoid body [GO:0033391]; cytoplasm [GO:0005737]; dense body [GO:0097433]; nucleus [GO:0005634]; P granule [GO:0043186] metal ion binding [GO:0046872]; mRNA binding [GO:0003729]; mRNA cap binding complex binding [GO:0140262]; piRNA binding [GO:0034584]; polysome binding [GO:1905538]; protein kinase binding [GO:0019901]; RNA endonuclease activity [GO:0004521]; single-stranded RNA binding [GO:0003727] 0.27562 0.83961 LIDYIHK 0 0 0 0 0 0 0 0 0 10.935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.52709 0 Q96JA1 LRIG1_HUMAN Leucine-rich repeats and immunoglobulin-like domains protein 1 (LIG-1) LRIG1 LIG1 Homo sapiens (Human) hair cycle process [GO:0022405]; innervation [GO:0060384]; otolith morphogenesis [GO:0032474]; sensory perception of sound [GO:0007605] extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] 0.75671 0.30616 AEGTPGPHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1755 0 0 0 0 0 0 0 0 Q96JA4 M4A14_HUMAN Membrane-spanning 4-domains subfamily A member 14 (Testis development protein NYD-SP21) MS4A14 MS4A13 MS4A16 Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166] plasma membrane [GO:0005886] 0.84136 0.18192 HSLNQQTK 0 0 9.44855 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96JB1 DYH8_HUMAN Dynein axonemal heavy chain 8 (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8) DNAH8 Homo sapiens (Human) cilium-dependent cell motility [GO:0060285]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] axonemal dynein complex [GO:0005858]; axoneme [GO:0005930]; microtubule [GO:0005874]; outer dynein arm [GO:0036157]; sperm flagellum [GO:0036126] ATP binding [GO:0005524]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; microtubule motor activity [GO:0003777]; minus-end-directed microtubule motor activity [GO:0008569] 0.96827 -9.4173 AYLKKYDPEVQLSK 12.7589 12.6339 12.9504 9.42465 0 0 12.5354 12.4822 12.4212 10.1888 13.0906 12.9909 11.6921 0 0 0 0 0 9.33166 10.9094 11.4796 0 9.44919 0 0 0 12.1984 Q96JB2 COG3_HUMAN Conserved oligomeric Golgi complex subunit 3 (COG complex subunit 3) (Component of oligomeric Golgi complex 3) (Vesicle-docking protein SEC34 homolog) (p94) COG3 SEC34 Homo sapiens (Human) "endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; glycosylation [GO:0070085]; Golgi organization [GO:0007030]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; protein glycosylation [GO:0006486]; protein localization to organelle [GO:0033365]; protein stabilization [GO:0050821]; retrograde transport, vesicle recycling within Golgi [GO:0000301]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]" cis-Golgi network [GO:0005801]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588] 0.87163 0.030444 LDDCITYISSHPNFK 0 0 0 0 0 0 12.466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96JB6 LOXL4_HUMAN Lysyl oxidase homolog 4 (EC 1.4.3.-) (Lysyl oxidase-like protein 4) (Lysyl oxidase-related protein C) LOXL4 LOXC Homo sapiens (Human) collagen fibril organization [GO:0030199]; peptidyl-lysine oxidation [GO:0018057] collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; receptor complex [GO:0043235] copper ion binding [GO:0005507]; protein-lysine 6-oxidase activity [GO:0004720]; scavenger receptor activity [GO:0005044] 0.91603 -0.84096 KGSWAEEPR 0 0 0 0 0 0 9.05295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96JB8 MPP4_HUMAN MAGUK p55 subfamily member 4 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein) (Discs large homolog 6) MPP4 ALS2CR5 DLG6 Homo sapiens (Human) protein localization to synapse [GO:0035418] actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] 0.89877 -0.66168 GADPPDKKDMK 0 10.5535 10.7492 0 8.40062 0 0 11.4148 0 0 0 0 0 0 0 12.4932 0 0 0 0 0 0 0 0 0 0 0 Q96JC1 VPS39_HUMAN Vam6/Vps39-like protein (TRAP1-like protein) (hVam6p) VPS39 KIAA0770 TLP VAM6 Homo sapiens (Human) autophagosome-lysosome fusion [GO:0061909]; autophagy [GO:0006914]; endocytic recycling [GO:0032456]; endosomal vesicle fusion [GO:0034058]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; late endosome to lysosome transport [GO:1902774]; regulation of SNARE complex assembly [GO:0035542] AP-3 adaptor complex [GO:0030123]; cytoplasm [GO:0005737]; endosome membrane [GO:0010008]; HOPS complex [GO:0030897]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lysosomal HOPS complex [GO:1902501]; lysosomal membrane [GO:0005765]; membrane [GO:0016020] 0.96761 -2.8998 ALQVLVDQSK 0 0 9.46809 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2177 0 0 Q96JC9 EAF1_HUMAN ELL-associated factor 1 EAF1 Homo sapiens (Human) regulation of transcription elongation by RNA polymerase II [GO:0034243]; transcription elongation by RNA polymerase II [GO:0006368] Cajal body [GO:0015030]; intercellular bridge [GO:0045171]; intracellular membrane-bounded organelle [GO:0043231]; nuclear body [GO:0016604]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; super elongation complex [GO:0032783]; transcription elongation factor complex [GO:0008023] transcription elongation factor activity [GO:0003711] 0.87014 0.058535 DNPSPEPQLDDIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.41785 0 0 Q96JD6 AKCL2_HUMAN "1,5-anhydro-D-fructose reductase (AF reductase) (EC 1.1.1.263) (Aldo-keto reductase family 1 member C-like protein 2) (Aldo-keto reductase family 1 member E2) (LoopADR) (Testis aldo-keto reductase) (htAKR) (Testis-specific protein) (hTSP)" AKR1E2 AKR1CL2 AKRDC1 Homo sapiens (Human) cytosol [GO:0005829] "1,5-anhydro-D-fructose reductase activity [GO:0050571]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; oxidoreductase activity [GO:0016491]" 0.84952 0.16551 EVGAGIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.2078 0 0 0 0 0 0 0 Q96JE7 SC16B_HUMAN Protein transport protein Sec16B (Leucine zipper transcription regulator 2) (Regucalcin gene promoter region-related protein p117) (RGPR-p117) (SEC16 homolog B) SEC16B KIAA1928 LZTR2 RGPR SEC16S Homo sapiens (Human) autophagy [GO:0006914]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; peroxisome fission [GO:0016559]; peroxisome organization [GO:0007031]; positive regulation of gene expression [GO:0010628]; positive regulation of protein exit from endoplasmic reticulum [GO:0070863]; protein localization to endoplasmic reticulum exit site [GO:0070973]; protein transport [GO:0015031] cytosol [GO:0005829]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231] 0.96224 -2.4858 SETLGSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.68503 10.4595 0 Q96JE9 MAP6_HUMAN Microtubule-associated protein 6 (MAP-6) (Stable tubule-only polypeptide) (STOP) MAP6 KIAA1878 Homo sapiens (Human) cytoskeleton-dependent intracellular transport [GO:0030705]; dendrite morphogenesis [GO:0048813]; lysosome localization [GO:0032418]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of axonogenesis [GO:0050772]; regulation of microtubule cytoskeleton organization [GO:0070507] axon [GO:0030424]; cis-Golgi network [GO:0005801]; dendrite [GO:0030425]; Golgi-associated vesicle [GO:0005798]; microtubule [GO:0005874]; perinuclear region of cytoplasm [GO:0048471]; transport vesicle membrane [GO:0030658] calmodulin binding [GO:0005516]; microtubule binding [GO:0008017] 0.63017 0.40958 AWKVQRPEPSCRPR 10.0743 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1193 0 Q96JF6 ZN594_HUMAN Zinc finger protein 594 (Zinc finger protein HZF18) ZNF594 KIAA1871 Homo sapiens (Human) nucleoplasm [GO:0005654] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.9696 -3.0394 HQVTHTREKPYECK 0 9.59124 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.92941 9.17632 0 0 0 0 0 Q96JG9 ZN469_HUMAN Zinc finger protein 469 ZNF469 KIAA1858 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of extracellular matrix organization [GO:1903053] nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.96937 -3.183 AAALPEETR 0 0 0 8.99129 0 0 8.55413 0 0 10.972 0 0 0 0 0 0 10.1473 9.66672 0 0 0 9.92981 0 0 0 0 0 Q96JH7 VCIP1_HUMAN Deubiquitinating protein VCPIP1 (EC 3.4.19.12) (Valosin-containing protein p97/p47 complex-interacting protein 1) (Valosin-containing protein p97/p47 complex-interacting protein p135) (VCP/p47 complex-interacting 135-kDa protein) VCPIP1 KIAA1850 VCIP135 Homo sapiens (Human) DNA damage response [GO:0006974]; endoplasmic reticulum membrane fusion [GO:0016320]; Golgi reassembly [GO:0090168]; mitotic cell cycle [GO:0000278]; protein deubiquitination [GO:0016579]; protein K11-linked deubiquitination [GO:0035871]; protein K48-linked deubiquitination [GO:0071108]; protein ubiquitination [GO:0016567]; protein-DNA covalent cross-linking repair [GO:0106300]; regulation of protein localization to chromatin [GO:1905634] cytoplasm [GO:0005737]; endoplasmic reticulum lumen [GO:0005788]; Golgi stack [GO:0005795]; nucleus [GO:0005634] cysteine-type deubiquitinase activity [GO:0004843] 0.61457 0.42373 LKQEQKGQPR 0 0 0 0 0 0 0 0 0 0 10.049 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.5003 Q96JH8 RADIL_HUMAN Ras-associating and dilute domain-containing protein RADIL KIAA1849 Homo sapiens (Human) neural crest cell migration [GO:0001755]; signal transduction [GO:0007165]; substrate adhesion-dependent cell spreading [GO:0034446] microtubule [GO:0005874]; protein-containing complex [GO:0032991] GTPase binding [GO:0051020] 0.96921 -4.9427 AVDLIRHGGK 0 0 0 0 0 0 0 0 0 8.68278 0 0 0 0 0 0 0 0 0 0 0 10.4952 0 0 0 9.16639 0 Q96JI7 SPTCS_HUMAN Spatacsin (Colorectal carcinoma-associated protein) (Spastic paraplegia 11 protein) SPG11 KIAA1840 Homo sapiens (Human) autophagosome organization [GO:1905037]; axo-dendritic transport [GO:0008088]; axon extension [GO:0048675]; chemical synaptic transmission [GO:0007268]; cholesterol efflux [GO:0033344]; corticospinal tract morphogenesis [GO:0021957]; localization within membrane [GO:0051668]; lysosome organization [GO:0007040]; memory [GO:0007613]; motor behavior [GO:0061744]; motor neuron apoptotic process [GO:0097049]; neuromuscular junction development [GO:0007528]; phagosome-lysosome fusion involved in apoptotic cell clearance [GO:0090389]; protein import into nucleus [GO:0006606]; regulation of store-operated calcium entry [GO:2001256]; skeletal muscle fiber development [GO:0048741]; synaptic vesicle transport [GO:0048489]; walking behavior [GO:0090659] axon [GO:0030424]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosomal membrane [GO:0005765]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; synapse [GO:0045202] protein kinase binding [GO:0019901] 0.96866 -5.7854 DFLVEILKEK 0 0 0 0 0 9.63303 0 0 0 0 0 0 0 0 12.4062 0 0 0 10.3258 0 10.0947 0 0 0 0 0 0 Q96JJ3 ELMO2_HUMAN Engulfment and cell motility protein 2 (Protein ced-12 homolog A) (hCed-12A) ELMO2 CED12A KIAA1834 Homo sapiens (Human) actin filament organization [GO:0007015]; apoptotic process [GO:0006915]; cell chemotaxis [GO:0060326]; cell motility [GO:0048870]; phagocytosis [GO:0006909] cytosol [GO:0005829]; membrane [GO:0016020] receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124] 0.95993 -1.9468 AIVTGKDCPHMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.32339 0 0 Q96JJ7 TMX3_HUMAN Protein disulfide-isomerase TMX3 (EC 5.3.4.1) (Thioredoxin domain-containing protein 10) (Thioredoxin-related transmembrane protein 3) TMX3 KIAA1830 TXNDC10 Homo sapiens (Human) peptidyl-cysteine oxidation [GO:0018171] cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092] protein disulfide isomerase activity [GO:0003756]; protein-disulfide reductase activity [GO:0015035] 0.88134 -0.30226 SIIQEVARDYR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3994 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96JK9 MAML3_HUMAN Mastermind-like protein 3 (Mam-3) MAML3 KIAA1816 Homo sapiens (Human) Notch signaling pathway [GO:0007219]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221] nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] transcription coactivator activity [GO:0003713] 0.88323 -0.037839 AHLSEDQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.677 0 0 9.24959 0 0 0 0 0 0 0 0 Q96JL9 ZN333_HUMAN Zinc finger protein 333 ZNF333 KIAA1806 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.8774 -0.011864 NLASVADQLCKPNALSYLEER 0 0 0 0 0 0 0 0 0 8.99597 0 0 0 0 0 0 0 0 0 0 9.10991 0 0 0 0 0 0 Q96JM2 ZN462_HUMAN Zinc finger protein 462 (Zinc finger PBX1-interacting protein) (ZFPIP) ZNF462 KIAA1803 Homo sapiens (Human) chromatin organization [GO:0006325]; negative regulation of DNA binding [GO:0043392]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468] nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.9695 -4.758 CDECPFTCK 0 0 0 9.99181 0 9.65152 0 10.9379 8.2998 0 0 10.8789 8.67751 10.2822 0 0 0 10.8364 0 10.6652 10.3165 0 0 0 0 0 0 Q96JM3 CHAP1_HUMAN Chromosome alignment-maintaining phosphoprotein 1 (Zinc finger protein 828) CHAMP1 C13orf8 CAMP CHAMP KIAA1802 ZNF828 Homo sapiens (Human) attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; protein localization to kinetochore [GO:0034501]; protein localization to microtubule [GO:0035372]; sister chromatid biorientation [GO:0031134] condensed chromosome [GO:0000793]; cytoplasm [GO:0005737]; kinetochore [GO:0000776]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819] metal ion binding [GO:0046872] 0.96765 -3.7102 AMKKGAVLHHLVNK 0 0 0 0 12.7322 0 0 0 8.65785 0 0 0 0 0 0 0 0 0 10.8787 0 0 0 0 0 10.2064 10.3492 0 Q96JM4 LRIQ1_HUMAN Leucine-rich repeat and IQ domain-containing protein 1 LRRIQ1 KIAA1801 Homo sapiens (Human) regulation of signal transduction [GO:0009966] 0.96991 -5.9798 EQFPLQELK 10.2649 0 12.5247 0 0 0 9.68745 11.3459 9.97255 0 0 9.76837 0 9.46504 10.347 10.948 0 0 9.88506 9.74888 0 0 0 0 9.47927 0 10.3621 Q96JM7 LMBL3_HUMAN Lethal(3)malignant brain tumor-like protein 3 (H-l(3)mbt-like protein 3) (L(3)mbt-like protein 3) (L3mbt-like 3) (MBT-1) L3MBTL3 KIAA1798 MBT1 Homo sapiens (Human) chromatin organization [GO:0006325]; erythrocyte maturation [GO:0043249]; granulocyte differentiation [GO:0030851]; macrophage differentiation [GO:0030225]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; regulation of DNA methylation-dependent heterochromatin formation [GO:0090308] nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; identical protein binding [GO:0042802]; methylation-dependent protein binding [GO:0140034]; zinc ion binding [GO:0008270] 0.96321 -2.1872 HIKDKDQK 0 0 0 0 0 0 0 0 0 15.4002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4402 10.5904 Q96JN0 LCOR_HUMAN Ligand-dependent corepressor (LCoR) (Mblk1-related protein 2) LCOR C10orf12 KIAA1795 MLR2 Homo sapiens (Human) cellular response to estradiol stimulus [GO:0071392]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; histone deacetylase binding [GO:0042826]; histone methyltransferase binding [GO:1990226]; nuclear estrogen receptor binding [GO:0030331]; transcription corepressor activity [GO:0003714]; transcription corepressor binding [GO:0001222]; ubiquitin-specific protease binding [GO:1990381] 0.86482 0.078179 IPQVRGMDLSWESR 0 0 0 0 8.78064 0 0 0 0 0 0 0 0 10.3309 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96JN2 CC136_HUMAN Coiled-coil domain-containing protein 136 (Nasopharyngeal carcinoma-associated gene 6 protein) CCDC136 KIAA1793 NAG6 Homo sapiens (Human) acrosome assembly [GO:0001675]; single fertilization [GO:0007338]; spermatogenesis [GO:0007283] acrosomal membrane [GO:0002080] 0.96866 -8.1104 EEMEEEK 0 0 0 0 0 0 0 0 0 10.2576 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96JN8 NEUL4_HUMAN Neuralized-like protein 4 NEURL4 KIAA1787 Homo sapiens (Human) centriole [GO:0005814]; cytoplasm [GO:0005737] ubiquitin protein ligase activity [GO:0061630] 0.8849 -0.19592 AEEVFEVK 0 10.1647 10.244 9.79875 0 9.4465 0 0 10.2348 9.19513 10.5483 9.18445 0 9.56102 9.97097 0 0 0 0 0 0 8.06829 12.8828 0 0 0 0 Q96JP0 FEM1C_HUMAN Protein fem-1 homolog C (FEM1c) (FEM1-gamma) FEM1C KIAA1785 Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] Cul2-RING ubiquitin ligase complex [GO:0031462]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; ubiquitin ligase complex [GO:0000151] ubiquitin ligase-substrate adaptor activity [GO:1990756] 0.96787 -3.6658 ILGPSHPDTSYYIR 0 0 0 0 0 0 0 0 0 10.4525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96JP2 MY15B_HUMAN Unconventional myosin-XVB (Myosin XVBP) (Unconventional myosin-15B) MYO15B KIAA1783 MYO15BP Homo sapiens (Human) cytoplasm [GO:0005737]; myosin complex [GO:0016459] ATP binding [GO:0005524]; cytoskeletal motor activity [GO:0003774] 0.88384 -0.31571 APKEAEAEPAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6595 0 0 Q96JP5 ZFP91_HUMAN E3 ubiquitin-protein ligase ZFP91 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase ZFP91) (Zinc finger protein 757) (Zinc finger protein 91 homolog) (Zfp-91) ZFP91 ZNF757 FKSG11 Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; protein K63-linked ubiquitination [GO:0070534]; regulation of transcription by RNA polymerase II [GO:0006357] nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] metal ion binding [GO:0046872]; ubiquitin-protein transferase activity [GO:0004842] 0.96175 -2.4556 AEYPRRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.72608 0 0 0 0 0 0 9.95942 0 Q96JQ0 PCD16_HUMAN Protocadherin-16 (Cadherin-19) (Cadherin-25) (Fibroblast cadherin-1) (Protein dachsous homolog 1) DCHS1 CDH19 CDH25 FIB1 KIAA1773 PCDH16 Homo sapiens (Human) branching involved in ureteric bud morphogenesis [GO:0001658]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell migration involved in endocardial cushion formation [GO:0003273]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cochlea development [GO:0090102]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; mitral valve formation [GO:0003192]; neural tube development [GO:0021915]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; pattern specification process [GO:0007389]; post-anal tail morphogenesis [GO:0036342]; protein localization to plasma membrane [GO:0072659] apical part of cell [GO:0045177]; catenin complex [GO:0016342]; membrane [GO:0016020] cadherin binding [GO:0045296]; calcium ion binding [GO:0005509] 0.93256 -1.2858 DPDLGEAAR 0 0 0 0 0 0 0 0 0 9.22142 0 0 0 0 0 0 0 10.9438 10.9292 0 0 0 0 0 0 0 0 Q96JS3 PGBD1_HUMAN PiggyBac transposable element-derived protein 1 (Cerebral protein 4) PGBD1 hucep-4 Homo sapiens (Human) membrane [GO:0016020] identical protein binding [GO:0042802]; scavenger receptor activity [GO:0005044]; sequence-specific DNA binding [GO:0043565] 0.8703 0.040185 ELCHQWLRPEMHTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0025 0 0 0 0 0 0 0 0 Q96JW4 S41A2_HUMAN Solute carrier family 41 member 2 SLC41A2 Homo sapiens (Human) cobalt ion transport [GO:0006824]; iron ion transport [GO:0006826]; magnesium ion transport [GO:0015693]; manganese ion transport [GO:0006828]; nickel cation transport [GO:0015675] plasma membrane [GO:0005886] magnesium ion transmembrane transporter activity [GO:0015095] 0.9233 -1.0468 NQEDRHKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.71359 0 0 0 0 0 0 0 0 0 0 0 0 Q96JY0 MAEL_HUMAN Protein maelstrom homolog MAEL Homo sapiens (Human) cell morphogenesis [GO:0000902]; DNA methylation involved in gamete generation [GO:0043046]; ectopic germ cell programmed cell death [GO:0035234]; fertilization [GO:0009566]; homologous chromosome pairing at meiosis [GO:0007129]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; male meiotic nuclear division [GO:0007140]; negative regulation of apoptotic process [GO:0043066]; negative regulation of developmental process [GO:0051093]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of reproductive process [GO:2000242]; negative regulation of transcription by RNA polymerase II [GO:0000122]; piRNA processing [GO:0034587]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of organ growth [GO:0046620]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] autosome [GO:0030849]; chromatin [GO:0000785]; chromatoid body [GO:0033391]; cytoplasm [GO:0005737]; male germ cell nucleus [GO:0001673]; nucleus [GO:0005634]; P granule [GO:0043186]; perinuclear region of cytoplasm [GO:0048471]; piP-body [GO:0071547]; XY body [GO:0001741] sequence-specific DNA binding [GO:0043565] 0.96962 -4.8201 ASRNAYYFFVQEK 0 0 0 0 0 0 0 0 0 8.68972 9.83939 9.44458 0 0 11.3129 0 0 0 0 0 0 0 0 0 0 0 0 Q96JY6 PDLI2_HUMAN PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) PDLIM2 PP6345 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; heart development [GO:0007507]; muscle structure development [GO:0061061]; protein catabolic process [GO:0030163] adherens junction [GO:0005912]; cortical actin cytoskeleton [GO:0030864]; filamentous actin [GO:0031941]; nucleus [GO:0005634]; stress fiber [GO:0001725]; Z disc [GO:0030018] actin binding [GO:0003779]; filamin binding [GO:0031005]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]; myosin heavy chain binding [GO:0032036]; ubiquitin protein ligase binding [GO:0031625] 0.94407 -1.3351 IQEGRYR 0 0 0 0 0 0 0 0 0 8.58256 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96K21 ANCHR_HUMAN Abscission/NoCut checkpoint regulator (ANCHR) (MLL partner containing FYVE domain) (Zinc finger FYVE domain-containing protein 19) ZFYVE19 ANCHR MPFYVE Homo sapiens (Human) abscission [GO:0009838]; cell division [GO:0051301]; mitotic cytokinesis checkpoint signaling [GO:0044878]; negative regulation of cytokinesis [GO:0032466] centrosome [GO:0005813]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; Flemming body [GO:0090543]; midbody [GO:0030496] metal ion binding [GO:0046872]; phosphatidylinositol-3-phosphate binding [GO:0032266] 0.86802 0.071082 CAGCDGDLFCARCFR 0 0 0 0 0 0 0 0 0 0 8.80597 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96K31 CH076_HUMAN Uncharacterized protein C8orf76 C8orf76 Homo sapiens (Human) 0.88446 -0.1552 IKDEVHPEVK 0 0 0 0 0 0 9.5751 9.45683 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96K37 S35E1_HUMAN Solute carrier family 35 member E1 SLC35E1 PSEC0038 Homo sapiens (Human) Golgi apparatus [GO:0005794]; membrane [GO:0016020] antiporter activity [GO:0015297] 0.88439 -0.13421 TKYDANQQAR 0 11.2545 0 0 0 0 0 0 0 0 0 0 0 0 0 9.76137 0 0 0 0 0 0 0 0 0 0 0 Q96K58 ZN668_HUMAN Zinc finger protein 668 ZNF668 Homo sapiens (Human) DNA repair [GO:0006281] nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.92321 -1.1595 AFLSASDLR 0 13.3712 0 0 0 0 0 0 0 0 0 0 0 10.4092 0 0 0 0 0 0 0 8.51487 0 9.91648 0 0 0 Q96K75 ZN514_HUMAN Zinc finger protein 514 ZNF514 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.95223 -1.4609 HLKQMSTIHK 0 0 0 9.44232 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96K76 UBP47_HUMAN Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.4.19.12) (Deubiquitinating enzyme 47) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) USP47 Homo sapiens (Human) base-excision repair [GO:0006284]; cellular response to UV [GO:0034644]; DNA damage response [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; monoubiquitinated protein deubiquitination [GO:0035520]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; protein deubiquitination [GO:0016579]; response to xenobiotic stimulus [GO:0009410]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005] cysteine-type deubiquitinase activity [GO:0004843]; cysteine-type endopeptidase activity [GO:0004197]; deubiquitinase activity [GO:0101005]; WD40-repeat domain binding [GO:0071987] 0.97023 -4.3154 AEGFFRSNK 0 0 13.0893 0 0 0 9.18646 0 9.39669 0 0 0 0 0 0 0 10.6354 0 0 0 0 0 0 0 0 0 0 Q96K78 AGRG7_HUMAN Adhesion G-protein coupled receptor G7 (G-protein coupled receptor 128) ADGRG7 GPR128 Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] membrane [GO:0016020] G protein-coupled receptor activity [GO:0004930] 0.95448 -1.5014 SLPSVTRPRLR 0 0 0 0 0 0 0 0 0 0 0 0 11.8237 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96K80 ZC3HA_HUMAN Zinc finger CCCH domain-containing protein 10 ZC3H10 ZC3HDC10 Homo sapiens (Human) negative regulation of miRNA processing [GO:1903799]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of RNA splicing [GO:0043484] nucleus [GO:0005634] metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; RNA binding [GO:0003723] 0.88424 -0.14193 GVECRLLEEENAMLRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.0898 0 0 0 0 0 0 0 0 0 0 Q96K83 ZN521_HUMAN Zinc finger protein 521 (Early hematopoietic zinc finger protein) (LYST-interacting protein 3) ZNF521 EHZF LIP3 Homo sapiens (Human) neuron fate commitment [GO:0048663] nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.95581 -1.5442 CTLCQEVFDSK 0 0 0 0 0 0 0 0 0 0 10.058 9.93656 0 0 0 0 0 10.1901 0 0 0 0 0 0 0 0 0 Q96KA5 CLP1L_HUMAN Lipid scramblase CLPTM1L (Cisplatin resistance-related protein 9) (CRR9p) (Cleft lip and palate transmembrane protein 1-like protein) (CLPTM1-like protein) CLPTM1L CRR9 Homo sapiens (Human) apoptotic process [GO:0006915] endomembrane system [GO:0012505]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] phospholipid scramblase activity [GO:0017128] 0.95415 -1.5273 SMIGMSTKAVLWR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.3307 0 0 0 0 Q96KB5 TOPK_HUMAN Lymphokine-activated killer T-cell-originated protein kinase (EC 2.7.12.2) (Cancer/testis antigen 84) (CT84) (MAPKK-like protein kinase) (Nori-3) (PDZ-binding kinase) (Spermatogenesis-related protein kinase) (SPK) (T-LAK cell-originated protein kinase) PBK TOPK Homo sapiens (Human) cellular response to UV [GO:0034644]; mitotic cell cycle [GO:0000278]; negative regulation of inflammatory response [GO:0050728]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of stress-activated MAPK cascade [GO:0032873]; peptidyl-serine phosphorylation [GO:0018105]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; stress-activated MAPK cascade [GO:0051403] nucleus [GO:0005634] ATP binding [GO:0005524]; MAP kinase kinase activity [GO:0004708]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713] 0.96783 -2.7909 SLNDLIEER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.77536 0 0 0 0 0 10.4713 0 0 0 0 0 Q96KC8 DNJC1_HUMAN DnaJ homolog subfamily C member 1 (DnaJ protein homolog MTJ1) DNAJC1 HTJ1 Homo sapiens (Human) negative regulation of proteolysis [GO:0045861]; protein folding [GO:0006457]; regulation of protein secretion [GO:0050708]; regulation of translation [GO:0006417] endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886] ATPase activator activity [GO:0001671]; DNA binding [GO:0003677]; protein-folding chaperone binding [GO:0051087] 0.969 -4.1943 FPGGTPGRWEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.2704 0 0 0 0 0 0 0 0 0 0 Q96KE9 BTBD6_HUMAN BTB/POZ domain-containing protein 6 (Lens BTB domain protein) BTBD6 BDPL Homo sapiens (Human) neurogenesis [GO:0022008] cytosol [GO:0005829] 0.87201 0.028842 GAASTGAEAAPAAPPAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.66589 0 0 0 0 0 0 0 Q96KG9 SCYL1_HUMAN N-terminal kinase-like protein (Coated vesicle-associated kinase of 90 kDa) (SCY1-like protein 1) (Telomerase regulation-associated protein) (Telomerase transcriptional element-interacting factor) (Teratoma-associated tyrosine kinase) SCYL1 CVAK90 GKLP NTKL TAPK TEIF TRAP HT019 Homo sapiens (Human) "inflammatory response [GO:0006954]; neuron development [GO:0048666]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; spinal cord motor neuron differentiation [GO:0021522]" cis-Golgi network [GO:0005801]; COPI vesicle coat [GO:0030126]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634] ATP binding [GO:0005524]; cadherin binding [GO:0045296]; DNA binding [GO:0003677]; protein tyrosine kinase activity [GO:0004713] 0.95342 -1.5004 ATRDPFAPSR 0 0 0 0 0 0 0 0 0 0 9.21466 9.38401 0 0 0 0 0 0 0 10.084 0 0 0 0 0 0 0 Q96KJ9 COX42_HUMAN "Cytochrome c oxidase subunit 4 isoform 2, mitochondrial (Cytochrome c oxidase subunit IV isoform 2) (COX IV-2)" COX4I2 COX4L2 Homo sapiens (Human) "cellular respiration [GO:0045333]; generation of precursor metabolites and energy [GO:0006091]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]" mitochondrial respiratory chain complex IV [GO:0005751] cytochrome-c oxidase activity [GO:0004129] 0.88334 -0.31316 AQQLQRMLDMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.52093 0 0 0 0 0 0 0 Q96KK4 O10C1_HUMAN Olfactory receptor 10C1 (Hs6M1-17) (Olfactory receptor 10C2) OR10C1 OR10C2 Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of smell [GO:0050911] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.91734 -0.862 IPSVAGR 11.4263 11.4611 11.3885 11.4587 11.4851 11.4697 11.6392 11.5917 11.564 12.3281 0 0 0 0 10.7317 0 0 0 10.6852 0 0 11.3915 11.4367 11.4217 0 9.19712 0 Q96KN2 CNDP1_HUMAN Beta-Ala-His dipeptidase (EC 3.4.13.20) (CNDP dipeptidase 1) (Carnosine dipeptidase 1) (Glutamate carboxypeptidase-like protein 2) (Serum carnosinase) CNDP1 CN1 CPGL2 UNQ1915/PRO4380 Homo sapiens (Human) proteolysis [GO:0006508]; regulation of protein metabolic process [GO:0051246] cytosol [GO:0005829]; extracellular region [GO:0005576] carboxypeptidase activity [GO:0004180]; dipeptidase activity [GO:0016805]; metal ion binding [GO:0046872]; metallodipeptidase activity [GO:0070573] 0.92728 -1.1939 LYGRGATDNK 0 0 0 0 0 0 0 9.44514 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96KN4 LRAT1_HUMAN Protein LRATD1 (LRAT domain-containing 1) (Neurologic sensory protein 1) (NSE1) (Protein FAM84A) LRATD1 FAM84A NSE1 Homo sapiens (Human) cell morphogenesis [GO:0000902]; cell motility [GO:0048870] cytoplasm [GO:0005737] 0.89755 -0.52947 FGKREFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.092 0 0 Q96KN7 RPGR1_HUMAN X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1) RPGRIP1 Homo sapiens (Human) neural precursor cell proliferation [GO:0061351]; non-motile cilium assembly [GO:1905515]; response to stimulus [GO:0050896]; retinal rod cell development [GO:0046548]; visual perception [GO:0007601] axoneme [GO:0005930]; photoreceptor connecting cilium [GO:0032391]; photoreceptor distal connecting cilium [GO:0120206] thromboxane A2 receptor binding [GO:0031870] 0.90385 -0.70607 VEDLEKER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.46991 9.90346 0 0 0 0 0 0 Q96KN9 CXD4_HUMAN Gap junction delta-4 protein (Connexin-40.1) (Cx40.1) GJD4 CX40.1 Homo sapiens (Human) cell-cell signaling [GO:0007267]; regulation of satellite cell activation involved in skeletal muscle regeneration [GO:0014717] connexin complex [GO:0005922] gap junction channel activity [GO:0005243] 0.60753 0.43499 EPASGQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.63996 0 0 0 0 Q96KP1 EXOC2_HUMAN Exocyst complex component 2 (Exocyst complex component Sec5) EXOC2 SEC5 SEC5L1 Homo sapiens (Human) exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; membrane fission [GO:0090148]; mitotic cytokinesis [GO:0000281]; protein transport [GO:0015031]; regulation of entry of bacterium into host cell [GO:2000535]; vesicle docking involved in exocytosis [GO:0006904]; vesicle tethering involved in exocytosis [GO:0090522] cytosol [GO:0005829]; exocyst [GO:0000145]; Flemming body [GO:0090543]; membrane [GO:0016020]; plasma membrane [GO:0005886] protein kinase binding [GO:0019901]; small GTPase binding [GO:0031267] 0.91623 -0.83887 DCLPPTGVRNYLK 8.2096 0 10.0027 10.8438 8.87295 0 0 0 10.1663 0 0 11.2815 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96KP4 CNDP2_HUMAN Cytosolic non-specific dipeptidase (EC 3.4.13.18) (CNDP dipeptidase 2) (Glutamate carboxypeptidase-like protein 1) (Peptidase A) (Threonyl dipeptidase) CNDP2 CN2 CPGL HEL-S-13 PEPA Homo sapiens (Human) proteolysis [GO:0006508] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654] alanylglutamate dipeptidase activity [GO:0103046]; carboxypeptidase activity [GO:0004180]; dipeptidase activity [GO:0016805]; metal ion binding [GO:0046872]; metallodipeptidase activity [GO:0070573] 0.005988 2.4616 AALTTLFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5193 0 0 0 0 9.88457 0 0 0 0 Q96KP6 TNIP3_HUMAN TNFAIP3-interacting protein 3 (A20-binding inhibitor of NF-kappa-B activation 3) (ABIN-3) (Listeria-induced gene protein) TNIP3 ABIN3 LIND Homo sapiens (Human) cellular response to lipopolysaccharide [GO:0071222]; inflammatory response [GO:0006954]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; regulation of transcription by RNA polymerase II [GO:0006357]; toll-like receptor 4 signaling pathway [GO:0034142] cytosol [GO:0005829] polyubiquitin modification-dependent protein binding [GO:0031593] 0.92502 -0.97011 DDRQREDDR 0 0 0 0 0 0 8.90599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96KQ4 ASPP1_HUMAN Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B) PPP1R13B ASPP1 KIAA0771 Homo sapiens (Human) intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; negative regulation of cell cycle [GO:0045786]; regulation of apoptotic process [GO:0042981] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] p53 binding [GO:0002039] 0.87617 -0.001689 NMEVAMMDK 0 0 0 0 0 0 0 0 0 0 0 0 0 8.11343 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96KQ7 EHMT2_HUMAN Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Lysine N-methyltransferase 1C) (Protein G9a) EHMT2 BAT8 C6orf30 G9A KMT1C NG36 Homo sapiens (Human) behavioral response to cocaine [GO:0048148]; cellular response to cocaine [GO:0071314]; cellular response to starvation [GO:0009267]; cellular response to xenobiotic stimulus [GO:0071466]; DNA methylation [GO:0006306]; DNA methylation on cytosine within a CG sequence [GO:0010424]; fertilization [GO:0009566]; histone lysine methylation [GO:0034968]; long-term memory [GO:0007616]; negative regulation of autophagosome assembly [GO:1902902]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron fate specification [GO:0048665]; oocyte development [GO:0048599]; organ growth [GO:0035265]; peptidyl-lysine dimethylation [GO:0018027]; phenotypic switching [GO:0036166]; regulation of DNA methylation [GO:0044030]; regulation of DNA replication [GO:0006275]; regulation of histone methylation [GO:0031060]; response to ethanol [GO:0045471]; response to fungicide [GO:0060992]; spermatid development [GO:0007286]; synaptonemal complex assembly [GO:0007130] chromatin [GO:0000785]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] C2H2 zinc finger domain binding [GO:0070742]; histone H3K27 methyltransferase activity [GO:0046976]; histone H3K56 methyltransferase activity [GO:0140759]; histone H3K9 methyltransferase activity [GO:0046974]; histone H3K9me2 methyltransferase activity [GO:0140947]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protein-lysine N-methyltransferase activity [GO:0016279]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; transcription corepressor binding [GO:0001222]; zinc ion binding [GO:0008270] 0.95487 -1.5778 IICRDVAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.44226 Q96KR1 ZFR_HUMAN Zinc finger RNA-binding protein (hZFR) (M-phase phosphoprotein homolog) ZFR Homo sapiens (Human) chromosome [GO:0005694]; cytoplasm [GO:0005737]; nucleus [GO:0005634] DNA binding [GO:0003677]; double-stranded RNA binding [GO:0003725]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]; zinc ion binding [GO:0008270] 0.92115 -1.1065 HATIYPTEEELQAVQK 0 0 0 0 0 0 0 0 0 0 0 0 10.6884 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96KR7 PHAR3_HUMAN Phosphatase and actin regulator 3 (Scaffold-associated PP1-inhibiting protein) (Scapinin) PHACTR3 C20orf101 SCAPIN1 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036] nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654] actin binding [GO:0003779]; protein phosphatase inhibitor activity [GO:0004864] 0.96165 -2.5902 ASSKTTK 10.0053 8.86793 9.09424 11.1461 11.3045 11.2923 0 0 0 11.313 10.6069 10.8103 0 11.7706 11.7764 13.152 13.5507 0 0 0 0 0 0 0 0 0 0 Q96KS9 F167A_HUMAN Protein FAM167A FAM167A C8orf13 Homo sapiens (Human) 0.95238 -1.478 GGQEPLLPLREAGQHPPSAR 0 0 0 0 0 0 0 0 0 0 0 0 11.4427 0 11.7839 11.9759 0 0 0 0 0 0 0 0 0 0 0 Q96KV7 WDR90_HUMAN WD repeat-containing protein 90 WDR90 C16orf15 C16orf16 C16orf17 C16orf18 C16orf19 KIAA1924 Homo sapiens (Human) cilium assembly [GO:0060271] centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737] 0.71209 0.36774 AVVGYSGNGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5498 0 0 0 0 0 Q96KW2 P12L2_HUMAN POM121-like protein 2 POM121L2 POM121L Homo sapiens (Human) protein import into nucleus [GO:0006606]; RNA export from nucleus [GO:0006405] nuclear pore [GO:0005643] nuclear localization sequence binding [GO:0008139]; structural constituent of nuclear pore [GO:0017056] 0.9562 -1.5434 GGTLSSKR 0 0 0 0 9.42545 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96KX1 CD036_HUMAN Uncharacterized protein C4orf36 C4orf36 Homo sapiens (Human) 0.9321 -1.2861 LEREYEVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.95591 0 0 10.2236 10.117 0 0 0 Q96L03 SPT17_HUMAN Spermatogenesis-associated protein 17 SPATA17 Homo sapiens (Human) establishment of meiotic spindle localization [GO:0051295]; mitotic cell cycle [GO:0000278]; spindle organization [GO:0007051] cytoplasm [GO:0005737]; spindle pole [GO:0000922] calmodulin binding [GO:0005516] 0.88366 -0.1068 ALEEFAEMKEREEK 10.0213 0 0 0 0 0 10.2922 0 0 0 9.48307 9.72146 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96L12 CALR3_HUMAN Calreticulin-3 (Calreticulin-2) (Calsperin) CALR3 CRT2 Homo sapiens (Human) cell differentiation [GO:0030154]; protein folding [GO:0006457]; spermatogenesis [GO:0007283]; ubiquitin-dependent ERAD pathway [GO:0030433] endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; nuclear envelope [GO:0005635] carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082] 0.95334 -1.501 DKGLQTTQNGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.24401 0 0 0 0 0 0 0 Q96L21 RL10L_HUMAN Ribosomal protein uL16-like (60S ribosomal protein L10-like) (Large ribosomal subunit protein uL16-like) RPL10L Homo sapiens (Human) cell differentiation [GO:0030154]; male meiosis I [GO:0007141]; ribosomal large subunit assembly [GO:0000027]; spermatogenesis [GO:0007283]; translation [GO:0006412] cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; endoplasmic reticulum [GO:0005783]; membrane [GO:0016020]; nucleus [GO:0005634]; polysome [GO:0005844]; ribosome [GO:0005840] structural constituent of ribosome [GO:0003735] 0.95396 -1.5243 YCKNKPYPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.84588 0 0 0 0 0 Q96L34 MARK4_HUMAN MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1) MARK4 KIAA1860 MARKL1 Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; cilium organization [GO:0044782]; intracellular signal transduction [GO:0035556]; microtubule bundle formation [GO:0001578]; microtubule cytoskeleton organization [GO:0000226]; nervous system development [GO:0007399]; positive regulation of cell cycle [GO:0045787]; positive regulation of cilium assembly [GO:0045724]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein localization to centrosome [GO:1904781]; protein phosphorylation [GO:0006468]; regulation of centrosome cycle [GO:0046605] centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; gamma-tubulin complex [GO:0000930]; microtubule cytoskeleton [GO:0015630]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; neuron projection [GO:0043005] ATP binding [GO:0005524]; cytoskeletal anchor activity [GO:0008093]; gamma-tubulin binding [GO:0043015]; microtubule binding [GO:0008017]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321]; ubiquitin binding [GO:0043130] 0.96196 -2.4619 GVLFRRVAGTALAFR 0 0 0 0 0 0 0 9.75273 0 0 10.3889 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96L42 KCNH8_HUMAN Potassium voltage-gated channel subfamily H member 8 (ELK1) (hElk1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (Voltage-gated potassium channel subunit Kv12.1) KCNH8 Homo sapiens (Human) potassium ion transmembrane transport [GO:0071805]; regulation of membrane potential [GO:0042391]; regulation of monoatomic ion transmembrane transport [GO:0034765] plasma membrane [GO:0005886] voltage-gated potassium channel activity [GO:0005249] 0.96401 -2.3846 AGTHFDSARR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8165 0 0 0 0 0 0 0 0 0 0 0 Q96L73 NSD1_HUMAN "Histone-lysine N-methyltransferase, H3 lysine-36 specific (EC 2.1.1.357) (Androgen receptor coactivator 267 kDa protein) (Androgen receptor-associated protein of 267 kDa) (H3-K36-HMTase) (Lysine N-methyltransferase 3B) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein)" NSD1 ARA267 KMT3B Homo sapiens (Human) methylation [GO:0032259]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription [GO:0006355]; regulation of peptidyl-serine phosphorylation [GO:0033135]; regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903025] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; histone H3K36 dimethyltransferase activity [GO:0140954]; histone H3K36 methyltransferase activity [GO:0046975]; histone H4K20 methyltransferase activity [GO:0042799]; nuclear androgen receptor binding [GO:0050681]; nuclear estrogen receptor binding [GO:0030331]; nuclear retinoic acid receptor binding [GO:0042974]; nuclear retinoid X receptor binding [GO:0046965]; nuclear thyroid hormone receptor binding [GO:0046966]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; transcription coregulator activity [GO:0003712]; transcription corepressor activity [GO:0003714]; zinc ion binding [GO:0008270] 0.96955 -5.4503 APASLPTEEK 0 9.74772 0 0 9.63427 9.54508 0 12.8476 0 12.5764 0 0 0 0 0 0 9.20345 0 0 0 0 10.5525 11.3139 11.4468 0 0 8.20139 Q96L91 EP400_HUMAN E1A-binding protein p400 (EC 3.6.4.-) (CAG repeat protein 32) (Domino homolog) (hDomino) (Trinucleotide repeat-containing gene 12 protein) (p400 kDa SWI2/SNF2-related protein) EP400 CAGH32 KIAA1498 KIAA1818 TNRC12 Homo sapiens (Human) DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of double-strand break repair [GO:2000779] NuA4 histone acetyltransferase complex [GO:0035267]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; Swr1 complex [GO:0000812] ATP binding [GO:0005524]; ATP-dependent chromatin remodeler activity [GO:0140658]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; helicase activity [GO:0004386]; hydrolase activity [GO:0016787]; protein antigen binding [GO:1990405] 0 2.8112 EHAAPYFQQLR 0 0 0 0 0 0 0 0 0 0 9.69469 8.71757 0 8.15411 0 10.355 9.564 8.97387 0 0 0 9.41022 0 0 0 0 0 Q96L92 SNX27_HUMAN Sorting nexin-27 SNX27 KIAA0488 My014 Homo sapiens (Human) endocytic recycling [GO:0032456]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; establishment of natural killer cell polarity [GO:0001770]; intracellular protein transport [GO:0006886]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; signal transduction [GO:0007165] cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; intracellular membrane-bounded organelle [GO:0043231]; Schaffer collateral - CA1 synapse [GO:0098685] phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-3-phosphate binding [GO:0032266] 0.96572 -2.3031 GEKKPRWVK 0 0 0 0 0 0 0 0 0 0 11.0038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96L93 KI16B_HUMAN Kinesin-like protein KIF16B (Sorting nexin-23) KIF16B C20orf23 KIAA1590 SNX23 Homo sapiens (Human) early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919] cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; kinesin complex [GO:0005871]; microtubule [GO:0005874]; spindle [GO:0005819] "ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; microtubule binding [GO:0008017]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; plus-end-directed microtubule motor activity [GO:0008574]" 0.96942 -3.0934 EILESREK 0 9.06488 13.714 0 0 0 0 9.59909 10.957 0 0 0 0 0 0 0 0 0 0 0 9.34012 0 0 0 0 0 9.98996 Q96L94 SNX22_HUMAN Sorting nexin-22 SNX22 Homo sapiens (Human) protein transport [GO:0015031] cytoplasmic vesicle membrane [GO:0030659] phosphatidylinositol phosphate binding [GO:1901981] 0.9634 -2.4396 LYKVPDFPSK 0 0 0 9.64938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4763 0 0 0 9.39343 0 0 Q96L96 ALPK3_HUMAN Alpha-protein kinase 3 (EC 2.7.11.1) (Muscle alpha-protein kinase) ALPK3 KIAA1330 MAK Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; heart development [GO:0007507]; protein phosphorylation [GO:0006468] nucleus [GO:0005634] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.95283 -1.4642 ALKEESGAK 0 0 0 0 0 0 9.76115 8.60833 0 9.55025 0 0 11.2665 0 9.80632 7.97877 8.94667 0 11.8743 11.756 0 0 0 0 0 0 0 Q96LA5 FCRL2_HUMAN Fc receptor-like protein 2 (FcR-like protein 2) (FcRL2) (Fc receptor homolog 2) (FcRH2) (IFGP family protein 4) (Immunoglobulin receptor translocation-associated protein 4) (SH2 domain-containing phosphatase anchor protein 1) (CD antigen CD307b) FCRL2 FCRH2 IFGP4 IRTA4 SPAP1 UNQ9236/PRO31998 Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; cell-cell signaling [GO:0007267] cell surface [GO:0009986]; membrane [GO:0016020]; plasma membrane [GO:0005886] protein phosphatase binding [GO:0019903]; signaling adaptor activity [GO:0035591]; transmembrane signaling receptor activity [GO:0004888] 0.86461 0.077719 CQGEQNWKIQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.17418 0 0 0 0 0 0 0 Q96LA8 ANM6_HUMAN Protein arginine N-methyltransferase 6 (EC 2.1.1.319) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6) (Histone-arginine N-methyltransferase PRMT6) PRMT6 HRMT1L6 Homo sapiens (Human) "base-excision repair [GO:0006284]; cellular senescence [GO:0090398]; histone modification [GO:0016570]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; protein modification process [GO:0036211]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of mitochondrion organization [GO:0010821]; regulation of signal transduction by p53 class mediator [GO:1901796]" nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; histone arginine N-methyltransferase activity [GO:0008469]; histone binding [GO:0042393]; histone H2AR3 methyltransferase activity [GO:0070612]; histone H3R2 methyltransferase activity [GO:0070611]; histone H4R3 methyltransferase activity [GO:0044020]; histone methyltransferase activity [GO:0042054]; protein-arginine N-methyltransferase activity [GO:0016274]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241] 0.94837 -1.3681 RKLESGGGGEGGEGTEEEDGAER 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2201 0 0 0 0 0 0 0 0 0 10.5272 0 0 0 Q96LB3 IFT74_HUMAN Intraflagellar transport protein 74 homolog (Capillary morphogenesis gene 1 protein) (CMG-1) (Coiled-coil domain-containing protein 2) IFT74 CCDC2 CMG1 Homo sapiens (Human) cilium assembly [GO:0060271]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; intraciliary anterograde transport [GO:0035720]; intraciliary transport involved in cilium assembly [GO:0035735]; keratinocyte development [GO:0003334]; keratinocyte proliferation [GO:0043616]; negative regulation of keratinocyte proliferation [GO:0010839]; non-motile cilium assembly [GO:1905515]; Notch signaling pathway [GO:0007219]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of transcription by RNA polymerase II [GO:0045944] acrosomal vesicle [GO:0001669]; centrosome [GO:0005813]; ciliary tip [GO:0097542]; cilium [GO:0005929]; intraciliary transport particle B [GO:0030992]; motile cilium [GO:0031514]; nucleus [GO:0005634] beta-tubulin binding [GO:0048487]; chromatin binding [GO:0003682] 0.84894 0.15735 QEAVLLHEK 0 0 0 0 0 0 0 0 0 0 9.03746 9.30494 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96LB8 PGRP4_HUMAN Peptidoglycan recognition protein 4 (Peptidoglycan recognition protein I-beta) (PGLYRPIbeta) (PGRP-I-beta) (Peptidoglycan recognition protein intermediate beta) PGLYRP4 PGRPIB SBBI67 Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; innate immune response [GO:0045087]; killing of cells of another organism [GO:0031640]; peptidoglycan catabolic process [GO:0009253] extracellular region [GO:0005576]; membrane [GO:0016020]; protein-containing complex [GO:0032991] N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; peptidoglycan immune receptor activity [GO:0016019]; protein heterodimerization activity [GO:0046982]; zinc ion binding [GO:0008270] 0.9511 -1.3838 ACPGVVPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7853 0 0 0 0 0 0 0 0 0 0 Q96LI5 CNO6L_HUMAN CCR4-NOT transcription complex subunit 6-like (EC 3.1.13.4) (Carbon catabolite repressor protein 4 homolog B) CNOT6L CCR4B Homo sapiens (Human) mRNA processing [GO:0006397]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; RNA-mediated gene silencing [GO:0031047] CCR4-NOT complex [GO:0030014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] metal ion binding [GO:0046872]; poly(A)-specific ribonuclease activity [GO:0004535] 0.82885 0.20412 GYDGFFSPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.43538 0 0 0 0 Q96LK0 CEP19_HUMAN Centrosomal protein of 19 kDa (Cep19) CEP19 C3orf34 HSD5 Homo sapiens (Human) "cilium assembly [GO:0060271]; microtubule anchoring at centrosome [GO:0034454]; vesicle targeting, trans-Golgi to periciliary membrane compartment [GO:0097712]" centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cilium [GO:0005929]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; spindle pole [GO:0000922] 0.93976 -1.305 SIMDELFEKNQKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8928 0 0 0 0 0 0 0 0 11.1227 Q96LL4 CH048_HUMAN Uncharacterized protein C8orf48 C8orf48 Homo sapiens (Human) 0.96291 -2.1838 IDEHLHTKDFLTR 0 0 0 9.16832 0 0 0 0 0 11.1987 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96LL9 DJC30_HUMAN "DnaJ homolog subfamily C member 30, mitochondrial (Williams-Beuren syndrome chromosomal region 18 protein)" DNAJC30 WBSCR18 Homo sapiens (Human) ATP biosynthetic process [GO:0006754]; brain development [GO:0007420]; regulation of mitochondrial ATP synthesis coupled proton transport [GO:1905706] mitochondrial inner membrane [GO:0005743] 0.92299 -1.1565 ISQAYVVLGSATLRR 0 0 0 0 0 0 0 0 0 9.36387 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96LM5 CD045_HUMAN Uncharacterized protein C4orf45 C4orf45 Homo sapiens (Human) 0.42411 0.66785 ASFAWHMSAFEDTDQRNSKWAILVR 0 0 0 0 0 0 0 0 0 0 0 0 10.7313 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96LM6 TEX37_HUMAN Testis-expressed sequence 37 protein (Testis-specific conserved protein of 21 kDa) TEX37 C2orf51 TSC21 Homo sapiens (Human) cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] 0.95332 -1.4964 LDAQLRDK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.19695 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96LP2 FA81B_HUMAN Protein FAM81B FAM81B Homo sapiens (Human) nucleus [GO:0005634] 0.87071 0.043059 SHAFLPIIPNTQR 0 0 0 0 0 0 0 0 12.0654 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96LQ0 PPR36_HUMAN Protein phosphatase 1 regulatory subunit 36 PPP1R36 C14orf50 Homo sapiens (Human) negative regulation of phosphatase activity [GO:0010923] phosphatase binding [GO:0019902]; protein phosphatase inhibitor activity [GO:0004864] 0.80948 0.2318 DDKSAKAVEK 0 0 0 0 0 0 0 8.98973 0 10.96 0 11.4402 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96LR2 LURA1_HUMAN Leucine rich adaptor protein 1 (Leucine repeat adapter protein 35A) LURAP1 C1orf190 LRAP35A LRP35A Homo sapiens (Human) positive regulation of cytokine production [GO:0001819]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123] cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231] 0.91979 -0.91045 KTPEGLLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1983 Q96LR4 TAFA4_HUMAN Chemokine-like protein TAFA-4 TAFA4 FAM19A4 Homo sapiens (Human) macrophage chemotaxis [GO:0048246]; phagocytosis [GO:0006909]; regulation of membrane potential [GO:0042391]; regulation of sensory perception of pain [GO:0051930]; regulation of signaling receptor activity [GO:0010469]; superoxide anion generation [GO:0042554] extracellular space [GO:0005615] receptor ligand activity [GO:0048018] 0.8817 -0.096655 IEERSQTVK 0 0 0 0 0 0 0 0 0 0 10.3889 0 0 0 0 0 0 0 9.80806 0 0 0 0 0 0 0 0 Q96LR9 APLD1_HUMAN Apolipoprotein L domain-containing protein 1 (Vascular early response gene protein) APOLD1 VERGE Homo sapiens (Human) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; lipid transport [GO:0006869]; lipoprotein metabolic process [GO:0042157]; regulation of endothelial cell differentiation [GO:0045601] extracellular region [GO:0005576]; plasma membrane [GO:0005886] lipid binding [GO:0008289] 0.9474 -1.3479 EVARRLER 0 0 0 0 0 0 0 0 0 0 0 10.7027 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96LT4 SAMD8_HUMAN Sphingomyelin synthase-related protein 1 (SMSr) (EC 2.7.8.-) (Ceramide phosphoethanolamine synthase) (CPE synthase) (Sterile alpha motif domain-containing protein 8) (SAM domain-containing protein 8) SAMD8 Homo sapiens (Human) ceramide biosynthetic process [GO:0046513]; ceramide phosphoethanolamine biosynthetic process [GO:1905373]; regulation of ceramide biosynthetic process [GO:2000303]; sphingolipid biosynthetic process [GO:0030148]; sphingomyelin biosynthetic process [GO:0006686] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] ceramide cholinephosphotransferase activity [GO:0047493]; ceramide phosphoethanolamine synthase activity [GO:0002950]; sphingomyelin synthase activity [GO:0033188] 0.82328 0.21604 AGPNQLCIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.83185 0 0 0 0 0 0 0 Q96LT9 RNPC3_HUMAN RNA-binding region-containing protein 3 (RNA-binding motif protein 40) (RNA-binding protein 40) (U11/U12 small nuclear ribonucleoprotein 65 kDa protein) (U11/U12 snRNP 65 kDa protein) (U11/U12-65K) RNPC3 KIAA1839 RBM40 RNP SNRNP65 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]" nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U12-type spliceosomal complex [GO:0005689] pre-mRNA intronic binding [GO:0097157]; U12 snRNA binding [GO:0030626] 0.87944 0.011688 IEFHISTDMPAAFK 0 0 0 0 0 0 0 0 10.7482 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96LU7 MRFL_HUMAN Myelin regulatory factor-like protein MYRFL C12orf15 C12orf28 Homo sapiens (Human) positive regulation of DNA-templated transcription [GO:0045893]; protein autoprocessing [GO:0016540] endoplasmic reticulum membrane [GO:0005789]; nucleus [GO:0005634] DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565] 0.55942 0.51941 LTNNLEER 0 0 11.2063 0 0 0 0 0 0 0 0 0 0 0 9.03138 0 0 0 0 0 0 0 0 0 0 0 0 Q96LW2 KS6R_HUMAN Ribosomal protein S6 kinase-related protein (EC 2.7.11.1) (Sugen kinase 494) RSKR SGK494 Homo sapiens (Human) protein phosphorylation [GO:0006468] ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.78789 0.25087 GVAFDPELLQK 9.17058 0 0 0 0 0 0 0 0 0 0 0 0 9.8467 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96LW7 CAR19_HUMAN Caspase recruitment domain-containing protein 19 (Bcl10-interacting CARD protein) (BinCARD) CARD19 C9orf89 Homo sapiens (Human) negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124] cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634] CARD domain binding [GO:0050700] 0.95197 -1.3838 LSEQQVDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.56281 0 0 0 Q96LW9 ZSC31_HUMAN Zinc finger and SCAN domain-containing protein 31 (Zinc finger protein 323) ZSCAN31 ZNF310P ZNF323 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96994 -5.2419 DVSLDSKYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.11189 0 0 10.3802 13.1218 0 Q96LZ2 MAGBA_HUMAN Melanoma-associated antigen B10 (MAGE-B10 antigen) MAGEB10 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] 0.87148 0.064428 DLVKENYLEYQQVPNSDPPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.80763 Q96LZ3 CANB2_HUMAN Calcineurin subunit B type 2 (Calcineurin B-like protein) (CBLP) (Calcineurin BII) (CNBII) (PPP3R1-like) (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform) PPP3R2 CBLP PPP3RL Homo sapiens (Human) calcineurin-mediated signaling [GO:0097720]; negative regulation of calcium ion import across plasma membrane [GO:1905949]; negative regulation of voltage-gated calcium channel activity [GO:1901386]; penetration of zona pellucida [GO:0007341]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of calcium ion import across plasma membrane [GO:1905665]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; protein dephosphorylation [GO:0006470] calcineurin complex [GO:0005955]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; protein serine/threonine phosphatase complex [GO:0008287]; sperm mitochondrial sheath [GO:0097226] calcium ion binding [GO:0005509]; calcium-dependent protein serine/threonine phosphatase regulator activity [GO:0008597]; phosphatase binding [GO:0019902] 0.93174 -1.2519 LRFAFSIYDMDKDGYISNGELFQVLK 0 0 0 0 0 0 0 0 0 9.84667 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96M02 CJ090_HUMAN (E2-independent) E3 ubiquitin-conjugating enzyme FATS (EC 2.3.2.-) (Centrosomal protein C10orf90) (E2/E3 hybrid ubiquitin-protein ligase FATS) (Fragile-site associated tumor suppressor homolog) (FATS) C10orf90 FATS Homo sapiens (Human) protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of centriole replication [GO:0046599] actin cytoskeleton [GO:0015629]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] microtubule binding [GO:0008017]; ubiquitin protein ligase activity [GO:0061630] 0.22944 0.8688 ASLPLPCAIAQSRAHHAK 0 0 0 0 0 0 0 0 0 10.9285 0 0 0 0 0 8.55662 0 0 0 0 8.59634 8.87061 0 0 10.6681 8.17867 10.6987 Q96M20 CNBD2_HUMAN Cyclic nucleotide-binding domain-containing protein 2 CNBD2 C20orf152 Homo sapiens (Human) spermatogenesis [GO:0007283] cytosol [GO:0005829] cAMP binding [GO:0030552] 0.88416 -0.13839 ELGLYQLAMDIIIMIRVCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6804 0 0 Q96M32 KAD7_HUMAN Adenylate kinase 7 (AK 7) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 7) AK7 Homo sapiens (Human) cell projection organization [GO:0030030]; nucleoside triphosphate biosynthetic process [GO:0009142]; phosphorylation [GO:0016310] cytoplasm [GO:0005737]; cytosol [GO:0005829]; motile cilium [GO:0031514] adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; cytidylate kinase activity [GO:0004127]; nucleoside diphosphate kinase activity [GO:0004550] 0.90717 -0.71227 ALDPEDSEVPFTEEDYR 0 0 0 0 0 0 0 0 0 0 10.1416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96M34 TEX55_HUMAN "Testis-specific expressed protein 55 (Testis-specific conserved, cAMP-dependent type II PK-anchoring protein)" TEX55 C3orf30 TSCPA Homo sapiens (Human) nucleus [GO:0005634] 0.5068 0.60885 LNYTSSQEK 0 0 0 0 9.8784 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96M42 CU129_HUMAN Putative uncharacterized protein encoded by LINC00479 LINC00479 C21orf129 PRED76 Homo sapiens (Human) 0.94033 -1.3098 LLIPRWR 11.2617 11.1576 0 0 0 0 12.2926 0 12.5643 0 12.7234 12.4435 0 0 10.6545 0 0 0 12.699 12.4134 12.3727 11.1584 11.0373 11.0293 13.3807 13.1988 13.0506 Q96M60 F227B_HUMAN Protein FAM227B FAM227B C15orf33 Homo sapiens (Human) 0.96376 -2.4122 EAKRQFAR 0 0 0 11.5376 0 0 0 0 0 8.59582 9.18411 0 10.3383 10.2851 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96M61 MAGBI_HUMAN Melanoma-associated antigen B18 (MAGE-B18 antigen) MAGEB18 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] cytoplasm [GO:0005737]; nucleus [GO:0005634] 0.88564 -0.33698 DEEQRTQAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.56142 0 0 0 0 0 Q96M63 ODAD1_HUMAN Outer dynein arm-docking complex subunit 1 (Coiled-coil domain-containing protein 114) ODAD1 CCDC114 Homo sapiens (Human) cilium movement [GO:0003341]; outer dynein arm assembly [GO:0036158] axoneme [GO:0005930]; cilium [GO:0005929]; outer dynein arm [GO:0036157]; outer dynein arm docking complex [GO:0120228] 0.93966 -1.3243 LVLCYEDALNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0651 0 9.19732 0 0 0 0 0 0 0 0 0 0 Q96M83 CCDC7_HUMAN Coiled-coil domain-containing protein 7 (Protein BIOT2) CCDC7 BIOT2 C10orf68 Homo sapiens (Human) 0.96913 -5.7706 EPNENLILRHQDSMSK 8.56932 8.63771 10.0251 0 0 11.5034 0 0 0 0 0 0 0 10.9753 10.9837 9.73081 0 0 0 0 0 9.14507 0 10.5641 0 0 0 Q96M86 DNHD1_HUMAN Dynein heavy chain domain-containing protein 1 (Coiled-coil domain-containing protein 35) (Dynein heavy chain domain 1-like protein) DNHD1 C11orf47 CCDC35 DHCD1 DNHD1L UNQ5781/PRO12970 Homo sapiens (Human) cilium movement [GO:0003341]; flagellated sperm motility [GO:0030317]; sperm flagellum assembly [GO:0120316] extracellular exosome [GO:0070062]; inner dynein arm [GO:0036156]; sperm flagellum [GO:0036126] ATP binding [GO:0005524]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; minus-end-directed microtubule motor activity [GO:0008569] 0.96937 -5.5611 EQPLACQQKQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8806 0 8.91907 0 12.6402 10.166 9.36717 Q96M91 CFA53_HUMAN Cilia- and flagella-associated protein 53 (Coiled-coil domain-containing protein 11) CFAP53 CCDC11 Homo sapiens (Human) cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287] axonemal microtubule [GO:0005879]; extracellular region [GO:0005576] 0.96345 -2.1339 HINESLKELNCEEK 0 0 0 0 0 0 0 0 0 9.9901 0 0 9.19889 0 0 0 0 0 0 9.05997 9.04319 0 0 10.0511 0 0 11.0912 Q96M94 KLH15_HUMAN Kelch-like protein 15 KLHL15 KIAA1677 Homo sapiens (Human) negative regulation of double-strand break repair via homologous recombination [GO:2000042]; nuclear protein quality control by the ubiquitin-proteasome system [GO:0071630]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] Cul3-RING ubiquitin ligase complex [GO:0031463]; nucleus [GO:0005634] ubiquitin ligase-substrate adaptor activity [GO:1990756] 0.88309 -0.10551 IMFTADMRERDQDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.332 0 0 0 0 0 0 0 0 0 0 0 0 Q96M95 CCD42_HUMAN Coiled-coil domain-containing protein 42 CCDC42 CCDC42A Homo sapiens (Human) spermatid development [GO:0007286] 0.96518 -2.2877 LARYMEEK 8.82909 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.9497 0 0 0 0 0 0 0 Q96M96 FGD4_HUMAN "FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament-binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6)" FGD4 FRABP ZFYVE6 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cytoskeleton organization [GO:0007010]; filopodium assembly [GO:0046847]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; lamellipodium [GO:0030027]; ruffle [GO:0001726] actin binding [GO:0003779]; guanyl-nucleotide exchange factor activity [GO:0005085]; metal ion binding [GO:0046872]; small GTPase binding [GO:0031267] 0.9163 -0.83686 FTVRTRVGIDGMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14.0533 0 0 0 0 0 0 0 0 0 0 0 Q96M98 PACRG_HUMAN Parkin coregulated gene protein (Molecular chaperone/chaperonin-binding protein) (PARK2 coregulated gene protein) PACRG GLUP Homo sapiens (Human) cellular response to unfolded protein [GO:0034620]; negative regulation of cell death [GO:0060548]; protein localization [GO:0008104]; spermatid development [GO:0007286] axonemal microtubule [GO:0005879]; cell body [GO:0044297]; cytosol [GO:0005829]; manchette [GO:0002177]; neuron projection [GO:0043005]; nucleus [GO:0005634]; sperm midpiece [GO:0097225]; vesicle [GO:0031982] actin binding [GO:0003779]; alpha-tubulin binding [GO:0043014]; beta-tubulin binding [GO:0048487]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; protein-folding chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625] 0.94803 -1.362 ETLSLNKCPDKMPK 0 0 0 0 0 0 0 0 0 0 0 10.3607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96MC2 DRC1_HUMAN Dynein regulatory complex protein 1 (Coiled-coil domain-containing protein 164) DRC1 C2orf39 CCDC164 Homo sapiens (Human) axonemal dynein complex assembly [GO:0070286]; cilium-dependent cell motility [GO:0060285]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; regulation of cilium movement [GO:0003352] axonemal dynein complex [GO:0005858]; axoneme [GO:0005930]; cytosol [GO:0005829]; motile cilium [GO:0031514] 0.96735 -2.3371 DEESTVIK 0 9.98085 0 0 0 8.87918 9.87557 0 0 0 0 0 11.3553 0 11.6625 0 0 0 0 0 9.17832 0 0 0 0 0 0 Q96MC4 C295L_HUMAN CEP295 N-terminal-like protein (KIAA1731 N-terminal like protein) CEP295NL KIAA1731NL Homo sapiens (Human) regulation of centriole replication [GO:0046599] centriole [GO:0005814]; centrosome [GO:0005813]; cilium [GO:0005929]; cytosol [GO:0005829] microtubule binding [GO:0008017] 0.96946 -4.0909 TDLKTFMGK 0 0 0 8.79867 0 0 0 0 0 0 0 0 0 0 0 9.36545 0 8.82553 9.91 0 0 0 0 0 0 0 0 Q96MC9 CA147_HUMAN Putative uncharacterized protein IKBKE-AS1 (IKBKE antisense RNA 1) (Uncharacterized protein C1orf147) IKBKE-AS1 C1orf147 Homo sapiens (Human) 0.86776 0.070894 SHFQCEFSSISK 0 0 0 0 0 0 0 0 0 0 9.83879 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96MF2 STAC3_HUMAN SH3 and cysteine-rich domain-containing protein 3 STAC3 Homo sapiens (Human) neuromuscular synaptic transmission [GO:0007274]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; skeletal muscle contraction [GO:0003009]; skeletal muscle fiber development [GO:0048741] cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nucleoplasm [GO:0005654]; synapse [GO:0045202]; T-tubule [GO:0030315]; voltage-gated calcium channel complex [GO:0005891] identical protein binding [GO:0042802]; metal ion binding [GO:0046872] 0.8807 0.0070705 AEKKTPDDK 0 0 0 0 0 0 0 0 0 0 9.90417 0 0 0 0 11.6974 0 0 0 0 0 0 0 0 0 0 0 Q96MF6 CQ10A_HUMAN "Coenzyme Q-binding protein COQ10 homolog A, mitochondrial" COQ10A UNQ6192/PRO20219 Homo sapiens (Human) cellular respiration [GO:0045333]; ubiquinone biosynthetic process [GO:0006744] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] ubiquinone binding [GO:0048039] 0.91283 -0.82254 EFVPWCKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.71249 0 0 0 0 Q96MG7 NSE3_HUMAN Non-structural maintenance of chromosomes element 3 homolog (Non-SMC element 3 homolog) (Hepatocellular carcinoma-associated protein 4) (MAGE-G1 antigen) (Melanoma-associated antigen G1) (Necdin-like protein 2) NSMCE3 HCA4 MAGEG1 NDNL2 Homo sapiens (Human) cellular response to hydroxyurea [GO:0072711]; cellular response to radiation [GO:0071478]; cellular response to UV [GO:0034644]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of protein ubiquitination [GO:0031398]; protein sumoylation [GO:0016925]; regulation of telomere maintenance [GO:0032204] "chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Smc5-Smc6 complex [GO:0030915]" protein dimerization activity [GO:0046983] 0.90557 -0.72919 ADILKHVIGDYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.80479 0 0 Q96MG8 PCMD1_HUMAN Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 PCMTD1 Homo sapiens (Human) protein ubiquitination [GO:0016567] Cul5-RING ubiquitin ligase complex [GO:0031466]; cytoplasm [GO:0005737]; membrane [GO:0016020] protein-L-isoaspartate (D-aspartate) O-methyltransferase activity [GO:0004719]; ubiquitin ligase-substrate adaptor activity [GO:1990756] 0.91558 -0.81004 AYLTYFR 0 0 0 0 0 0 9.87739 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96MH2 HEXI2_HUMAN Protein HEXIM2 (Hexamethylene bis-acetamide-inducible protein 2) HEXIM2 L3 Homo sapiens (Human) negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 7SK snRNA binding [GO:0097322]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; identical protein binding [GO:0042802]; snRNA binding [GO:0017069] 0.8779 -0.012043 DYLELEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.4184 0 0 0 0 0 0 0 0 0 0 0 Q96MH7 CE034_HUMAN Uncharacterized protein C5orf34 C5orf34 Homo sapiens (Human) 0.96127 -2.5639 FLTSDISEERGK 9.24722 0 0 0 0 0 8.57777 0 0 0 0 8.85978 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96MI9 CBPC4_HUMAN Cytosolic carboxypeptidase 4 (EC 3.4.17.-) (EC 3.4.17.24) (ATP/GTP-binding protein-like 1) (Protein deglutamylase CCP4) AGBL1 CCP4 Homo sapiens (Human) C-terminal protein deglutamylation [GO:0035609]; protein side chain deglutamylation [GO:0035610]; proteolysis [GO:0006508] cytosol [GO:0005829] metallocarboxypeptidase activity [GO:0004181]; tubulin binding [GO:0015631]; zinc ion binding [GO:0008270] 0.9276 -1.222 ALELEALDVTLILAR 10.9557 0 0 9.53327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96MK2 RIPR3_HUMAN RIPOR family member 3 RIPOR3 C20orf175 C20orf176 FAM65C Homo sapiens (Human) 0.95965 -1.8604 LAFEKMDK 0 0 0 0 0 0 0 0 0 0 10.2268 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96MK3 FA20A_HUMAN Pseudokinase FAM20A FAM20A UNQ9388/PRO34279 Homo sapiens (Human) biomineral tissue development [GO:0031214]; calcium ion homeostasis [GO:0055074]; enamel mineralization [GO:0070166]; positive regulation of protein phosphorylation [GO:0001934]; response to bacterium [GO:0009617]; tooth eruption [GO:0044691] cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794] protein serine/threonine kinase activator activity [GO:0043539] 0.96817 -2.8856 LSVPNPWIR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.67442 0 0 0 0 0 0 0 9.58613 0 0 0 0 0 Q96MM3 ZFP42_HUMAN Zinc finger protein 42 homolog (Zfp-42) (Reduced expression protein 1) (REX-1) (hREX-1) (Zinc finger protein 754) ZFP42 REX1 ZNF754 Homo sapiens (Human) female gonad development [GO:0008585]; male gonad development [GO:0008584]; meiotic cell cycle [GO:0051321]; regulation of transcription by RNA polymerase II [GO:0006357] cytoplasm [GO:0005737]; PcG protein complex [GO:0031519]; transcription regulator complex [GO:0005667] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.51549 0.59277 IVGENSLEYSEYMTGKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.85493 9.7051 0 0 0 0 0 0 0 0 0 0 Q96MM6 HS12B_HUMAN Heat shock 70 kDa protein 12B HSPA12B C20orf60 Homo sapiens (Human) ATP binding [GO:0005524] 0.89912 -0.61562 DWLYFEK 8.97997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96MM7 H6ST2_HUMAN Heparan-sulfate 6-O-sulfotransferase 2 (HS6ST-2) (EC 2.8.2.-) HS6ST2 PSEC0092 Homo sapiens (Human) "heparan sulfate proteoglycan biosynthetic process, enzymatic modification [GO:0015015]" Golgi membrane [GO:0000139] heparan sulfate 6-O-sulfotransferase activity [GO:0017095] 0.92383 -1.0716 DLFLQRYQFMR 0 0 0 0 9.14389 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0993 0 Q96MN2 NALP4_HUMAN "NACHT, LRR and PYD domains-containing protein 4 (Cancer/testis antigen 58) (CT58) (PAAD and NACHT-containing protein 2) (PAN2) (PYRIN and NACHT-containing protein 2) (PYRIN-containing APAF1-like protein 4) (PYPAF4) (Ribonuclease inhibitor 2)" NLRP4 NALP4 PAN2 PYPAF4 RNH2 Homo sapiens (Human) inflammatory response [GO:0006954]; regulation of inflammatory response [GO:0050727] cytoplasm [GO:0005737]; cytosol [GO:0005829] ATP binding [GO:0005524] 0.969 -5.8308 DLCMKVMR 8.90165 0 0 10.2345 0 0 0 0 10.3417 9.91163 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96MP5 ZSWM3_HUMAN Zinc finger SWIM domain-containing protein 3 ZSWIM3 C20orf164 Homo sapiens (Human) zinc ion binding [GO:0008270] 0.87376 0.025088 SLVEPSFCLDK 0 0 0 0 0 0 8.33954 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96MR6 CFA57_HUMAN Cilia- and flagella-associated protein 57 (WD repeat-containing protein 65) CFAP57 WDR65 Homo sapiens (Human) 0.92187 -1.1379 EKRIYDLK 0 10.609 10.449 0 0 9.02506 12.0091 11.6269 12.0914 11.3901 10.4701 10.5007 0 11.6613 10.4118 0 11.4722 0 0 0 9.6395 11.2303 0 9.8775 11.141 10.7185 11.0577 Q96MR7 OBAS1_HUMAN Putative uncharacterized protein OBSCN-AS1 (OBSCN antisense RNA 1) (OBSCN antisense gene protein 1) OBSCN-AS1 C1orf145 Homo sapiens (Human) 0.88924 -0.42904 GTAGSAR 0 0 9.59733 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3323 0 0 Q96MR9 ZN560_HUMAN Zinc finger protein 560 ZNF560 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.73098 0.3355 LYQCKKCGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.52376 0 0 0 0 Q96MS0 ROBO3_HUMAN Roundabout homolog 3 (Roundabout-like protein 3) ROBO3 Homo sapiens (Human) axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; dendrite self-avoidance [GO:0070593]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] axon [GO:0030424]; membrane [GO:0016020]; plasma membrane [GO:0005886] cell-cell adhesion mediator activity [GO:0098632] 0.95208 -1.3922 IVEQPPDLLVSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.23759 0 0 0 0 0 Q96MS3 GL1D1_HUMAN Glycosyltransferase 1 domain-containing protein 1 (EC 2.4.-.-) GLT1D1 Homo sapiens (Human) cytosol [GO:0005829]; extracellular region [GO:0005576] glycosyltransferase activity [GO:0016757] 0.9537 -1.4986 NTVMGRVLEEAR 0 0 0 9.86471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96MT1 RN145_HUMAN RING finger protein 145 (EC 2.3.2.27) RNF145 Homo sapiens (Human) endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789] transferase activity [GO:0016740]; zinc ion binding [GO:0008270] 0.82304 0.21588 AFMNDPAMNR 0 9.13532 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96MT3 PRIC1_HUMAN Prickle-like protein 1 (REST/NRSF-interacting LIM domain protein 1) PRICKLE1 RILP Homo sapiens (Human) "anterior visceral endoderm cell migration [GO:1905070]; aorta development [GO:0035904]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; basement membrane organization [GO:0071711]; bone mineralization [GO:0030282]; cardiac muscle cell development [GO:0055013]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; cornea development in camera-type eye [GO:0061303]; coronary vasculature development [GO:0060976]; cytoskeleton-dependent intracellular transport [GO:0030705]; dendrite development [GO:0016358]; embryonic brain development [GO:1990403]; embryonic nail plate morphogenesis [GO:0035880]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of bipolar cell polarity involved in cell morphogenesis [GO:0061159]; extracellular matrix assembly [GO:0085029]; eyelid development in camera-type eye [GO:0061029]; face morphogenesis [GO:0060325]; focal adhesion disassembly [GO:0120181]; gene expression [GO:0010467]; mesenchyme development [GO:0060485]; mitotic spindle assembly [GO:0090307]; multicellular organism growth [GO:0035264]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle cell myoblast differentiation [GO:2000691]; negative regulation of DNA-templated transcription [GO:0045892]; neural tube closure [GO:0001843]; neuron projection extension [GO:1990138]; outflow tract morphogenesis [GO:0003151]; planar cell polarity pathway involved in axis elongation [GO:0003402]; polarized secretion of basement membrane proteins in epithelium [GO:0061865]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein import into nucleus [GO:0006606]; renal tubule development [GO:0061326]; response to electrical stimulus [GO:0051602]; response to xenobiotic stimulus [GO:0009410]; tear secretion [GO:0070075]; tissue homeostasis [GO:0001894]; vesicle-mediated transport [GO:0016192]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" cell trailing edge [GO:0031254]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; proteasome complex [GO:0000502] protein-containing complex binding [GO:0044877]; zinc ion binding [GO:0008270] 0.92042 -0.91731 CSACDEIIFADECTEAEGR 12.5744 0 10.7708 0 0 0 12.1978 12.3201 12.2678 0 0 9.09748 0 0 0 9.62207 9.66878 10.5811 0 9.82361 0 0 0 0 0 0 0 Q96MT7 CFA44_HUMAN Cilia- and flagella-associated protein 44 (WD repeat-containing protein 52) CFAP44 WDR52 Homo sapiens (Human) microtubule cytoskeleton organization [GO:0000226]; sperm axoneme assembly [GO:0007288] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; motile cilium [GO:0031514] peptidase activity [GO:0008233] 0.96968 -6.0012 EKEIQPADL 11.702 0 10.9648 0 0 0 10.5986 0 10.4268 9.04352 0 10.0462 0 0 9.82039 11.0793 0 0 0 0 0 0 0 0 0 0 0 Q96MT8 CEP63_HUMAN Centrosomal protein of 63 kDa (Cep63) CEP63 Homo sapiens (Human) cell division [GO:0051301]; centriole replication [GO:0007099]; de novo centriole assembly involved in multi-ciliated epithelial cell differentiation [GO:0098535]; DNA damage checkpoint signaling [GO:0000077]; negative regulation of innate immune response [GO:0045824]; negative regulation of protein K63-linked ubiquitination [GO:1900045]; protein stabilization [GO:0050821]; signal transduction in response to DNA damage [GO:0042770]; spindle assembly [GO:0051225] centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; spindle pole [GO:0000922] molecular adaptor activity [GO:0060090] 0.96968 -4.3326 DLMNTKSQLEISTQMCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.515 0 0 Q96MU5 CQ077_HUMAN Uncharacterized protein CD300LD-AS1 (CD300LD antisense RNA 1) CD300LD-AS1 C17orf77 Homo sapiens (Human) extracellular region [GO:0005576] 0.8986 -0.62311 APATLTWEDEKQQR 0 0 0 0 0 0 0 0 0 0 9.35546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96MU6 ZN778_HUMAN Zinc finger protein 778 ZNF778 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.95561 -1.5457 GPALRQDR 0 0 0 11.0723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96MU7 YTDC1_HUMAN YTH domain-containing protein 1 (Splicing factor YT521) (YT521-B) YTHDC1 KIAA1966 YT521 Homo sapiens (Human) "dosage compensation by inactivation of X chromosome [GO:0009048]; in utero embryonic development [GO:0001701]; mRNA alternative polyadenylation [GO:0110104]; mRNA export from nucleus [GO:0006406]; mRNA splice site selection [GO:0006376]; mRNA splicing, via spliceosome [GO:0000398]; post-transcriptional regulation of gene expression [GO:0010608]; primary follicle stage [GO:0048160]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of mRNA splicing, via spliceosome [GO:0048024]; spermatogenesis [GO:0007283]" nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] mRNA binding [GO:0003729]; N6-methyladenosine-containing RNA binding [GO:1990247]; RNA binding [GO:0003723] 0.96167 -2.0522 KSDRMESTDTK 0 0 0 0 0 0 0 0 0 0 9.68422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96MV1 TLCD4_HUMAN TLC domain-containing protein 4 (Transmembrane protein 56) TLCD4 TMEM56 Homo sapiens (Human) lipid homeostasis [GO:0055088] endoplasmic reticulum [GO:0005783]; membrane [GO:0016020] 0.95292 -1.4638 ISKGCIK 0 0 0 0 0 0 0 0 0 11.4697 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96MV8 ZDH15_HUMAN Palmitoyltransferase ZDHHC15 (EC 2.3.1.225) (Acyltransferase ZDHHC15) (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 15) (DHHC-15) ZDHHC15 UNQ1969/PRO4501 Homo sapiens (Human) peptidyl-L-cysteine S-palmitoylation [GO:0018230]; positive regulation of dendrite development [GO:1900006]; protein localization to membrane [GO:0072657]; protein localization to postsynapse [GO:0062237]; protein palmitoylation [GO:0018345]; protein targeting to Golgi apparatus [GO:0140450]; protein targeting to membrane [GO:0006612]; regulation of dendritic spine morphogenesis [GO:0061001]; synaptic vesicle maturation [GO:0016188] endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069] palmitoyltransferase activity [GO:0016409]; protein-cysteine S-myristoyltransferase activity [GO:0019705]; protein-cysteine S-palmitoyltransferase activity [GO:0019706]; protein-cysteine S-stearoyltransferase activity [GO:0140439]; zinc ion binding [GO:0008270] 0.95262 -1.4642 MALSGGLR 0 0 9.14748 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96MW5 COG8_HUMAN Conserved oligomeric Golgi complex subunit 8 (COG complex subunit 8) (Component of oligomeric Golgi complex 8) COG8 Homo sapiens (Human) "glycosylation [GO:0070085]; Golgi organization [GO:0007030]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]; retrograde transport, vesicle recycling within Golgi [GO:0000301]" Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; membrane [GO:0016020]; trans-Golgi network membrane [GO:0032588] 0.9154 -0.7939 DLAFANYK 0 0 0 0 0 9.00039 0 0 0 0 0 0 0 0 0 0 10.1733 0 0 0 0 0 0 0 0 0 0 Q96MW7 TIGD1_HUMAN Tigger transposable element-derived protein 1 TIGD1 Homo sapiens (Human) nucleus [GO:0005634] DNA binding [GO:0003677] 0.95588 -1.5949 ALTLFNSMK 0 0 9.81954 0 0 11.7694 9.25831 0 0 9.77015 0 0 0 0 11.823 0 0 0 0 0 0 0 0 0 0 0 0 Q96MZ4 F218A_HUMAN Protein FAM218A FAM218A C4orf39 Homo sapiens (Human) 0.88845 -0.40232 SEGPPGK 0 0 0 0 0 0 0 8.60507 0 0 0 9.01198 8.65069 9.32935 9.08574 0 10.247 9.25065 0 10.6845 8.65832 8.8515 0 8.57992 0 0 9.91425 Q96N11 INT15_HUMAN Integrator complex subunit 15 INTS15 C7orf26 Homo sapiens (Human) integrator complex [GO:0032039] 0.87029 0.054607 IPVLECAASWLQR 0 9.11447 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96N16 JKIP1_HUMAN Janus kinase and microtubule-interacting protein 1 (GABA-B receptor-binding protein) (Multiple alpha-helices and RNA-linker protein 1) (Marlin-1) JAKMIP1 GABABRBP JAMIP1 MARLIN1 Homo sapiens (Human) cognition [GO:0050890]; protein transport [GO:0015031] cytoplasm [GO:0005737]; membrane [GO:0016020]; microtubule [GO:0005874]; ribonucleoprotein complex [GO:1990904] GABA receptor binding [GO:0050811]; kinase binding [GO:0019900]; microtubule binding [GO:0008017]; RNA binding [GO:0003723] 0.9627 -2.1559 AKLTSIQIEFQQEK 8.41193 9.89271 0 0 0 0 12.6565 0 0 0 0 0 0 0 0 0 0 0 0 10.3487 0 0 0 0 0 0 0 Q96N21 AP4AT_HUMAN AP-4 complex accessory subunit Tepsin (ENTH domain-containing protein 2) (Epsin for AP-4) (Tetra-epsin) TEPSIN C17orf56 ENTHD2 Homo sapiens (Human) coated vesicle membrane [GO:0030662]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; nuclear speck [GO:0016607]; trans-Golgi network membrane [GO:0032588] 0.95206 -1.3898 IPGGTDSPKRGPSSCAWSR 12.5547 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.513 0 0 0 0 0 0 0 0 0 Q96N22 ZN681_HUMAN Zinc finger protein 681 ZNF681 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.18325 0.9468 SIHTGEKPYQCEK 0 0 0 0 0 0 0 9.42708 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96N23 CFA54_HUMAN Cilia- and flagella-associated protein 54 CFAP54 C12orf55 C12orf63 Homo sapiens (Human) cerebrospinal fluid circulation [GO:0090660]; cilium assembly [GO:0060271]; cilium movement involved in cell motility [GO:0060294]; establishment of localization in cell [GO:0051649]; mucociliary clearance [GO:0120197]; sperm flagellum assembly [GO:0120316]; spermatogenesis [GO:0007283] axoneme [GO:0005930]; extracellular region [GO:0005576] 0.96946 -4.5907 AEGSYGK 0 0 0 0 0 0 12.7389 0 0 0 0 9.35365 0 0 9.87231 0 10.0756 11.5087 0 0 0 9.38418 10.1258 0 11.2216 11.9673 0 Q96N46 TTC14_HUMAN Tetratricopeptide repeat protein 14 (TPR repeat protein 14) TTC14 KIAA1980 UNQ5813/PRO19630 Homo sapiens (Human) nucleic acid binding [GO:0003676] 0.96944 -6.3778 CVKIGVDYFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4433 9.8106 9.66231 0 0 0 0 10.2515 0 0 0 0 Q96N53 CK037_HUMAN Putative uncharacterized protein encoded by LINC00167 (PRDM10-DT divergent transcript) PRDM10-DT C11orf37 LINC00167 NCRNA00167 Homo sapiens (Human) 0.83476 0.18775 ANGEEASSCAWVSR 0 8.65428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96N58 ZN578_HUMAN Zinc finger protein 578 ZNF578 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.95995 -1.9 AIHTGEKPYK 0 10.7509 10.6084 0 0 0 0 0 10.9718 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96N64 PWP2A_HUMAN PWWP domain-containing protein 2A PWWP2A KIAA1935 MST101 Homo sapiens (Human) chromatin remodeling [GO:0006338]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; regulation of transcriptional start site selection at RNA polymerase II promoter [GO:0001178] nucleus [GO:0005634] chromatin binding [GO:0003682]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; NuRD complex binding [GO:0120325] 0.88932 -0.44785 TICVGDIVWAK 0 0 0 0 0 0 0 0 0 0 0 0 10.6 0 0 0 0 0 10.3245 0 0 0 10.0996 0 0 0 0 Q96N67 DOCK7_HUMAN Dedicator of cytokinesis protein 7 DOCK7 KIAA1771 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; axonogenesis [GO:0007409]; establishment of neuroblast polarity [GO:0045200]; interkinetic nuclear migration [GO:0022027]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of cold-induced thermogenesis [GO:0120163]; neuron projection development [GO:0031175]; positive regulation of GTPase activity [GO:0043547]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; regulation of neurogenesis [GO:0050767]; small GTPase mediated signal transduction [GO:0007264] axon [GO:0030424]; basal part of cell [GO:0045178]; focal adhesion [GO:0005925]; growth cone [GO:0030426]; neuron projection [GO:0043005] guanyl-nucleotide exchange factor activity [GO:0005085]; small GTPase binding [GO:0031267] 0.96863 -7.7368 DFTKRCEDALR 0 0 0 0 0 0 0 9.2863 0 0 9.62967 0 10.0657 0 0 8.81762 0 0 9.8732 9.57881 0 0 9.05485 0 0 11.1292 0 Q96N68 CR015_HUMAN Putative uncharacterized protein C18orf15 C18orf15 Homo sapiens (Human) membrane [GO:0016020] 0.6502 0.39598 QGQGALK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.84847 0 0 Q96N95 ZN396_HUMAN Zinc finger protein 396 (Zinc finger and SCAN domain-containing protein 14) ZNF396 ZSCAN14 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.93033 -1.2354 IHSGKKPYACDECAK 0 0 0 10.0883 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.08619 0 0 0 0 0 0 Q96N96 SPT13_HUMAN Spermatogenesis-associated protein 13 (APC-stimulated guanine nucleotide exchange factor 2) (Asef2) SPATA13 Homo sapiens (Human) cell migration [GO:0016477]; filopodium assembly [GO:0046847]; lamellipodium assembly [GO:0030032]; regulation of cell migration [GO:0030334]; regulation of small GTPase mediated signal transduction [GO:0051056] cytoplasm [GO:0005737]; cytosol [GO:0005829]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; nucleoplasm [GO:0005654]; ruffle membrane [GO:0032587] guanyl-nucleotide exchange factor activity [GO:0005085]; identical protein binding [GO:0042802] 0.88187 -0.30413 AAYEAMK 0 0 0 0 0 0 0 0 0 0 0 9.92807 0 0 0 0 0 0 0 0 0 0 0 0 10.7363 0 0 Q96NB1 CEP20_HUMAN Centrosomal protein 20 (FGFR1OP N-terminal-like protein) (FOP-related protein of 20 kDa) (LisH domain-containing protein FOPNL) CEP20 C16orf63 FOPNL FOR20 PHSECRG2 Homo sapiens (Human) cilium assembly [GO:0060271]; microtubule anchoring [GO:0034453] centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; motile cilium [GO:0031514]; nucleoplasm [GO:0005654] identical protein binding [GO:0042802] 0.96789 -2.7848 ATVAELKAVLK 0 0 0 0 0 0 9.34454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96NB2 SFXN2_HUMAN Sideroflexin-2 SFXN2 Homo sapiens (Human) mitochondrial transmembrane transport [GO:1990542]; serine import into mitochondrion [GO:0140300] mitochondrial inner membrane [GO:0005743]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739] monoatomic ion transmembrane transporter activity [GO:0015075]; serine transmembrane transporter activity [GO:0022889] 0.68704 0.38828 ELDWAKVMVEKSR 9.71096 9.61782 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96NB3 ZN830_HUMAN Zinc finger protein 830 (Coiled-coil domain-containing protein 16) ZNF830 CCDC16 Homo sapiens (Human) blastocyst growth [GO:0001832]; cell division [GO:0051301]; chromosome organization [GO:0051276]; intestinal epithelial structure maintenance [GO:0060729]; mitotic DNA damage checkpoint signaling [GO:0044773]; mitotic DNA replication checkpoint signaling [GO:0033314]; mRNA processing [GO:0006397]; negative regulation of apoptotic process [GO:0043066]; nuclear DNA replication [GO:0033260]; ovarian follicle development [GO:0001541]; preantral ovarian follicle growth [GO:0001546]; RNA processing [GO:0006396]; RNA splicing [GO:0008380] chromosome [GO:0005694]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681] nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270] 0.19565 0.92861 KAPDADDQDVK 0 0 0 0 9.5002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0463 0 0 Q96NC0 ZMAT2_HUMAN Zinc finger matrin-type protein 2 ZMAT2 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]" nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540] DNA binding [GO:0003677]; zinc ion binding [GO:0008270] 0.96929 -4.2597 ELREEEEK 0 0 0 0 0 0 8.93151 0 0 0 0 0 9.77691 0 0 0 0 0 0 0 11.5783 0 0 0 0 10.6466 0 Q96ND0 F210A_HUMAN Protein FAM210A FAM210A C18orf19 Homo sapiens (Human) cytoplasm [GO:0005737]; membrane [GO:0016020]; mitochondrion [GO:0005739] 0.95573 -1.5889 TFRQYGK 0 0 0 0 0 0 0 0 9.77717 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96ND8 ZN583_HUMAN Zinc finger protein 583 (Zinc finger protein L3-5) ZNF583 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.91592 -0.77588 KAFSQYAHLAQHQR 0 0 0 0 0 0 0 0 0 9.27429 0 0 0 0 9.75409 0 0 0 0 0 0 0 0 0 0 0 0 Q96NE9 FRMD6_HUMAN FERM domain-containing protein 6 (Willin) FRMD6 C14orf31 Homo sapiens (Human) apical constriction [GO:0003383]; positive regulation of hippo signaling [GO:0035332]; protein localization [GO:0008104]; regulation of actin filament-based process [GO:0032970] apical junction complex [GO:0043296]; cytoplasm [GO:0005737]; cytoplasmic side of apical plasma membrane [GO:0098592]; cytoskeleton [GO:0005856]; plasma membrane [GO:0005886] 0.95979 -1.7199 LIYYTGCPMRSR 0 0 9.33472 0 0 0 0 10.0583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96NG3 ODAD4_HUMAN Outer dynein arm-docking complex subunit 4 (Tetratricopeptide repeat protein 25) (TPR repeat protein 25) ODAD4 TTC25 Homo sapiens (Human) brain development [GO:0007420]; cerebrospinal fluid circulation [GO:0090660]; cilium movement [GO:0003341]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; heart development [GO:0007507]; lung development [GO:0030324]; mucociliary clearance [GO:0120197]; outer dynein arm assembly [GO:0036158]; protein localization to motile cilium [GO:0120229] 9+0 motile cilium [GO:0097728]; 9+2 motile cilium [GO:0097729]; axoneme [GO:0005930]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; outer dynein arm docking complex [GO:0120228] 0.9188 -0.893 ALDNIGR 0 9.83761 9.63517 0 0 0 0 0 12.8259 0 7.92244 0 0 9.29724 0 9.8464 0 0 0 0 0 0 0 0 0 0 0 Q96NH3 BROMI_HUMAN Protein broad-minded (TBC1 domain family member 32) TBC1D32 BROMI C6orf170 C6orf171 Homo sapiens (Human) determination of left/right symmetry [GO:0007368]; embryonic digit morphogenesis [GO:0042733]; heart development [GO:0007507]; kidney development [GO:0001822]; lens development in camera-type eye [GO:0002088]; non-motile cilium assembly [GO:1905515]; protein localization to cilium [GO:0061512]; retinal pigment epithelium development [GO:0003406]; roof of mouth development [GO:0060021]; smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] cilium [GO:0005929]; cytoplasm [GO:0005737] 0.61295 0.42174 LLNEYQK 0 0 0 0 9.90127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.88332 0 Q96NI6 LRFN5_HUMAN Leucine-rich repeat and fibronectin type-III domain-containing protein 5 LRFN5 C14orf146 SALM5 Homo sapiens (Human) negative regulation of inflammatory response [GO:0050728]; negative regulation of macrophage activation [GO:0043031]; regulation of presynapse assembly [GO:1905606]; synaptic membrane adhesion [GO:0099560] cell surface [GO:0009986]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; postsynaptic density membrane [GO:0098839] 0.83609 0.18931 QAVGHEENAQCCK 0 0 0 0 0 0 14.7305 0 0 0 0 0 0 10.1128 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96NI8 ZN570_HUMAN Zinc finger protein 570 ZNF570 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.77683 0.26323 AFSQFAYLAQHQR 0 0 0 0 0 0 0 0 0 9.96809 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.895 0 Q96NJ3 ZN285_HUMAN Zinc finger protein 285 (Zinc finger protein 285A) ZNF285 ZNF285A Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.85069 0.16571 CDECGKGFSRNSDLNVHLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.44083 0 0 0 0 0 0 Q96NJ5 KLH32_HUMAN Kelch-like protein 32 (BTB and kelch domain-containing protein 5) KLHL32 BKLHD5 KIAA1900 Homo sapiens (Human) 0.96386 -2.2255 NKWTFVQSFDR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.92939 0 0 0 0 0 0 9.56621 0 0 0 0 0 0 Q96NJ6 ZFP3_HUMAN Zinc finger protein 3 homolog (Zfp-3) (Zinc finger protein 752) ZFP3 ZNF752 Homo sapiens (Human) nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.89841 -0.55521 ECGKAFRGNSELLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.6325 0 0 0 0 0 0 0 0 0 0 Q96NL1 TMM74_HUMAN Transmembrane protein 74 TMEM74 Homo sapiens (Human) "general adaptation syndrome, behavioral process [GO:0051867]; macroautophagy [GO:0016236]; regulation of cation channel activity [GO:2001257]" autophagosome membrane [GO:0000421]; cytoplasmic vesicle [GO:0031410]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886] transmembrane transporter binding [GO:0044325] 0.71613 0.36557 NRFASSKESAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.97928 0 0 0 0 0 0 0 Q96NL3 ZN599_HUMAN Zinc finger protein 599 ZNF599 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.95075 -1.406 HNRIHTGEKPFECK 10.7611 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2744 0 0 0 0 0 0 0 0 0 0 0 0 Q96NL6 SCLT1_HUMAN Sodium channel and clathrin linker 1 (Sodium channel-associated protein 1) SCLT1 SAP1 Homo sapiens (Human) cilium assembly [GO:0060271]; clustering of voltage-gated sodium channels [GO:0045162] centriole [GO:0005814]; centrosome [GO:0005813]; ciliary transition fiber [GO:0097539]; clathrin complex [GO:0071439]; cytosol [GO:0005829] clathrin binding [GO:0030276]; sodium channel regulator activity [GO:0017080] 0.95303 -1.472 EVANTKK 0 0 0 8.99129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.0077 Q96NM4 TOX2_HUMAN TOX high mobility group box family member 2 (Granulosa cell HMG box protein 1) (GCX-1) TOX2 C20orf100 GCX1 Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin DNA binding [GO:0031490]; transcription coactivator activity [GO:0003713] 0.3088 0.79766 IVASMWDSLGEEQKQSSPDQGETKSTQANPPAK 0 0 0 0 0 0 0 0 0 0 0 0 9.96694 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96NN9 AIFM3_HUMAN Apoptosis-inducing factor 3 (EC 1.-.-.-) (Apoptosis-inducing factor-like protein) AIFM3 AIFL Homo sapiens (Human) execution phase of apoptosis [GO:0097194] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] "2 iron, 2 sulfur cluster binding [GO:0051537]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on NAD(P)H [GO:0016651]" 0.96849 -3.9142 IVLCTLDR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.73454 0 0 0 0 0 0 0 0 0 0 0 9.69125 0 Q96NR8 RDH12_HUMAN Retinol dehydrogenase 12 (EC 1.1.1.300) (All-trans and 9-cis retinol dehydrogenase) (Short chain dehydrogenase/reductase family 7C member 2) RDH12 SDR7C2 Homo sapiens (Human) cellular detoxification of aldehyde [GO:0110095]; photoreceptor cell maintenance [GO:0045494]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; visual perception [GO:0007601] endoplasmic reticulum membrane [GO:0005789]; photoreceptor inner segment [GO:0001917]; photoreceptor inner segment membrane [GO:0060342] 11-cis-retinol dehydrogenase activity [GO:0102354]; NAD-retinol dehydrogenase activity [GO:0004745]; NADP-retinol dehydrogenase activity [GO:0052650] 0.96175 -2.0493 AFAEGFLAEEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2622 0 0 0 0 Q96NS8 CLUP3_HUMAN Putative protein CLUHP3 (Clustered mitochondria (cluA/CLU1) homolog pseudogene 3) (KIAA0664-like protein 3) CLUHP3 C16orf67 KIAA0664L3 Homo sapiens (Human) 0.20852 0.91038 ACCSTWWK 10.0602 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2622 0 0 0 0 Q96NT5 PCFT_HUMAN Proton-coupled folate transporter (HsPCFT) (hPCFT) (Heme carrier protein 1) (PCFT/HCP1) (Solute carrier family 46 member 1) SLC46A1 G21 HCP1 PCFT Homo sapiens (Human) folate import across plasma membrane [GO:1904447]; folate transmembrane transport [GO:0098838]; folic acid metabolic process [GO:0046655]; folic acid transport [GO:0015884]; heme metabolic process [GO:0042168]; intestinal folate absorption [GO:0098829]; intracellular iron ion homeostasis [GO:0006879]; proton transmembrane transport [GO:1902600]; transmembrane transport [GO:0055085] apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; endosome [GO:0005768]; endosome membrane [GO:0010008]; plasma membrane [GO:0005886] folic acid binding [GO:0005542]; folic acid transmembrane transporter activity [GO:0008517]; folic acid:proton symporter activity [GO:0140211]; heme transmembrane transporter activity [GO:0015232]; methotrexate transmembrane transporter activity [GO:0015350]; proton transmembrane transporter activity [GO:0015078]; symporter activity [GO:0015293]; transmembrane transporter activity [GO:0022857] 0.88249 -0.27241 FSADLGYNGTRQR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.06983 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96NU1 SAM11_HUMAN Sterile alpha motif domain-containing protein 11 (SAM domain-containing protein 11) SAMD11 Homo sapiens (Human) nucleus [GO:0005634] 0.96162 -2.0769 ISSDCFSEKRAR 0 9.19754 0 0 0 0 0 0 9.37234 0 0 0 0 8.64627 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96NW4 ANR27_HUMAN Ankyrin repeat domain-containing protein 27 (VPS9 domain-containing protein) ANKRD27 PP12899 Homo sapiens (Human) early endosome to late endosome transport [GO:0045022]; endocytic recycling [GO:0032456]; endosome to melanosome transport [GO:0035646]; negative regulation of SNARE complex assembly [GO:0035544]; neuron projection morphogenesis [GO:0048812]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of neuron projection development [GO:0010976]; protein transport [GO:0015031] cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; early endosome [GO:0005769]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane [GO:0016020]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]; tubular endosome [GO:0097422] GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; small GTPase binding [GO:0031267]; SNARE binding [GO:0000149] 0.96226 -2.5134 LKETPLK 0 0 10.5379 8.06032 0 0 8.48361 0 0 9.15833 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96NW7 LRRC7_HUMAN Leucine-rich repeat-containing protein 7 (Densin-180) (Densin) (Protein LAP1) LRRC7 KIAA1365 LAP1 Homo sapiens (Human) "neurotransmitter receptor transport postsynaptic membrane to endosome [GO:0098968]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive regulation of neuron projection development [GO:0010976]" adherens junction [GO:0005912]; axon initial segment [GO:0043194]; cytosol [GO:0005829]; extracellular region [GO:0005576]; postsynaptic density [GO:0014069]; specific granule lumen [GO:0035580] 0.96578 -2.2948 EQQPYEGNINK 0 0 0 0 0 0 0 0 0 0 0 0 10.9769 0 0 0 0 0 0 0 0 0 0 0 10.5539 0 0 Q96NX9 DACH2_HUMAN Dachshund homolog 2 (Dach2) DACH2 Homo sapiens (Human) development of primary female sexual characteristics [GO:0046545] nucleus [GO:0005634]; transcription regulator complex [GO:0005667] RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96321 -2.1639 KDFETLFTDCTNAR 0 0 0 0 0 0 9.49356 0 0 0 11.3642 0 0 0 0 0 0 0 11.4462 0 0 10.2947 0 0 0 0 0 Q96NY9 MUS81_HUMAN Crossover junction endonuclease MUS81 (EC 3.1.22.-) MUS81 Homo sapiens (Human) DNA catabolic process [GO:0006308]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via break-induced replication [GO:0000727]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; osteoblast proliferation [GO:0033687]; replication fork processing [GO:0031297]; resolution of meiotic recombination intermediates [GO:0000712]; response to intra-S DNA damage checkpoint signaling [GO:0072429] endodeoxyribonuclease complex [GO:1905347]; Holliday junction resolvase complex [GO:0048476]; nuclear replication fork [GO:0043596]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; replication fork [GO:0005657] 3'-flap endonuclease activity [GO:0048257]; crossover junction DNA endonuclease activity [GO:0008821]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872] 0.92757 -1.2026 EAKILQHFGDGLCR 0 11.8118 11.9058 0 0 0 0 11.65 0 0 11.3135 0 0 0 0 0 0 12.1969 0 0 0 0 0 0 0 10.0783 0 Q96NZ1 FOXN4_HUMAN Forkhead box protein N4 FOXN4 Homo sapiens (Human) amacrine cell differentiation [GO:0035881]; atrioventricular canal development [GO:0036302]; heart looping [GO:0001947]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of heart contraction [GO:0008016]; retina layer formation [GO:0010842]; ventral spinal cord interneuron differentiation [GO:0021514]; ventral spinal cord interneuron fate commitment [GO:0060579] chromatin [GO:0000785]; nucleus [GO:0005634] "chromatin binding [GO:0003682]; cis-regulatory region sequence-specific DNA binding [GO:0000987]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]" 0.87344 0.031991 LISDRPESCR 0 0 0 0 0 0 0 0 0 0 0 8.80781 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96P09 BIRC8_HUMAN Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis-like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis) BIRC8 ILP2 Homo sapiens (Human) negative regulation of apoptotic process [GO:0043066]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of protein ubiquitination [GO:0031398]; regulation of cell cycle [GO:0051726] cytoplasm [GO:0005737]; nucleus [GO:0005634] cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630] 0.91445 -0.78173 EISPEEPLRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.71788 0 0 0 0 0 0 0 0 0 0 Q96P16 RPR1A_HUMAN Regulation of nuclear pre-mRNA domain-containing protein 1A (Cyclin-dependent kinase inhibitor 2B-related protein) (p15INK4B-related protein) RPRD1A P15RS Homo sapiens (Human) mRNA 3'-end processing [GO:0031124]; RNA polymerase II promoter clearance [GO:0001111] "nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II, holoenzyme [GO:0016591]; transcription preinitiation complex [GO:0097550]" identical protein binding [GO:0042802]; RNA polymerase II complex binding [GO:0000993] 0.96971 -5.4414 HSRPIVTVWERELRK 8.80903 0 0 8.93843 0 0 0 0 0 13.1746 14.3759 12.5554 0 0 0 12.5328 12.5158 13.8809 9.6082 9.25925 9.39622 9.7749 0 0 0 9.7938 10.4028 Q96P20 NLRP3_HUMAN "NACHT, LRR and PYD domains-containing protein 3 (EC 3.6.4.-) (Angiotensin/vasopressin receptor AII/AVP-like) (Caterpiller protein 1.1) (CLR1.1) (Cold-induced autoinflammatory syndrome 1 protein) (Cryopyrin) (PYRIN-containing APAF1-like protein 1)" NLRP3 C1orf7 CIAS1 NALP3 PYPAF1 Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to virus [GO:0098586]; defense response [GO:0006952]; detection of biotic stimulus [GO:0009595]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; NLRP3 inflammasome complex assembly [GO:0044546]; osmosensory signaling pathway [GO:0007231]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type 2 immune response [GO:0002830]; protein homooligomerization [GO:0051260]; protein maturation [GO:0051604]; pyroptosis [GO:0070269]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; interphase microtubule organizing center [GO:0031021]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; mitochondrion [GO:0005739]; NLRP3 inflammasome complex [GO:0072559]; nucleus [GO:0005634] ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; cysteine-type endopeptidase activator activity [GO:0140608]; DNA-binding transcription factor binding [GO:0140297]; identical protein binding [GO:0042802]; molecular adaptor activity [GO:0060090]; molecular condensate scaffold activity [GO:0140693]; peptidoglycan binding [GO:0042834]; phosphatidylinositol phosphate binding [GO:1901981]; phosphatidylinositol-4-phosphate binding [GO:0070273]; sequence-specific DNA binding [GO:0043565]; signaling adaptor activity [GO:0035591]; small molecule sensor activity [GO:0140299] 0.92728 -1.2057 HLLCNLK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2397 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96P26 5NT1B_HUMAN Cytosolic 5'-nucleotidase 1B (cN1B) (EC 3.1.3.5) (Autoimmune infertility-related protein) (Cytosolic 5'-nucleotidase IB) (cN-IB) NT5C1B AIRP FKSG85 Homo sapiens (Human) adenosine metabolic process [GO:0046085]; purine nucleotide catabolic process [GO:0006195] cytosol [GO:0005829]; nucleus [GO:0005634] 5'-nucleotidase activity [GO:0008253]; magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; XMP 5'-nucleosidase activity [GO:0106411] 0.96406 -2.2712 ISRSPSTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0875 0 0 0 0 0 0 0 0 0 0 0 Q96P44 COLA1_HUMAN Collagen alpha-1(XXI) chain COL21A1 COL1AL FP633 Homo sapiens (Human) collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576] 0.88145 -0.025879 GLPGYKGEPGR 0 0 0 0 0 0 0 0 9.42469 0 0 0 0 0 0 0 10.8147 0 0 0 0 0 0 0 0 0 0 Q96P47 AGAP3_HUMAN "Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 (AGAP-3) (CRAM-associated GTPase) (CRAG) (Centaurin-gamma-3) (Cnt-g3) (MR1-interacting protein) (MRIP-1)" AGAP3 CENTG3 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; cellular response to reactive oxygen species [GO:0034614]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] cell periphery [GO:0071944]; cytoplasm [GO:0005737]; nucleus [GO:0005634] GTP binding [GO:0005525]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; polyubiquitin modification-dependent protein binding [GO:0031593] 0.96798 -2.8822 ARKLSTDLK 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3765 0 0 0 0 0 0 11.0144 0 0 0 0 0 0 Q96P50 ACAP3_HUMAN "Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 (Centaurin-beta-5) (Cnt-b5)" ACAP3 CENTB5 KIAA1716 Homo sapiens (Human) neuron migration [GO:0001764]; regulation of neuron projection development [GO:0010975] cytoplasm [GO:0005737]; growth cone [GO:0030426] GTPase activator activity [GO:0005096]; metal ion binding [GO:0046872] 0.84093 0.181 GVKGESVLQR 0 0 0 0 0 0 0 0 0 0 0 10.6457 0 0 0 0 0 0 0 0 0 0 0 0 0 9.68555 0 Q96P53 WDFY2_HUMAN WD repeat and FYVE domain-containing protein 2 (Propeller-FYVE protein) (Prof) (WD40- and FYVE domain-containing protein 2) (Zinc finger FYVE domain-containing protein 22) WDFY2 WDF2 ZFYVE22 Homo sapiens (Human) positive regulation of fat cell differentiation [GO:0045600]; positive regulation of protein phosphorylation [GO:0001934] early endosome [GO:0005769]; intracellular membrane-bounded organelle [GO:0043231]; vesicle [GO:0031982] metal ion binding [GO:0046872] 0.93157 -1.2725 IGLRQHHCR 0 0 0 0 0 0 0 0 0 9.76155 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96P64 AGAP4_HUMAN "Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4 (AGAP-4) (Centaurin-gamma-like family member 1) (Centaurin-gamma-like family member 5)" AGAP4 AGAP8 CTGLF1 CTGLF5 MRIP2 Homo sapiens (Human) activation of GTPase activity [GO:0090630] GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872] 0.95969 -1.9378 LNPPPSPHANK 10.0395 0 0 0 10.453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.87599 0 0 0 0 0 Q96P66 GP101_HUMAN Probable G-protein coupled receptor 101 GPR101 Homo sapiens (Human) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880] plasma membrane [GO:0005886]; receptor complex [GO:0043235] G protein-coupled receptor activity [GO:0004930] 0.96291 -2.6651 DCVENEDEEGAEK 0 0 0 0 0 0 0 0 0 11.961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96P69 GPR78_HUMAN G-protein coupled receptor 78 GPR78 UNQ5925/PRO19818 Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930] 0.87174 0.029637 AVADPFTYSLLR 0 0 0 0 0 0 0 0 0 0 9.22848 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96P70 IPO9_HUMAN Importin-9 (Imp9) (Ran-binding protein 9) (RanBP9) IPO9 IMP9 KIAA1192 RANBP9 HSPC273 Homo sapiens (Human) proteasome localization [GO:0031144]; protein import into nucleus [GO:0006606] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nuclear envelope [GO:0005635] histone binding [GO:0042393]; histone chaperone activity [GO:0140713]; nuclear import signal receptor activity [GO:0061608]; small GTPase binding [GO:0031267] 0.16364 0.98804 ELGENLDQILR 0 0 0 0 0 0 8.86171 0 0 0 0 0 0 0 0 0 10.2922 0 0 0 0 0 0 0 10.1329 0 0 Q96P71 NECA3_HUMAN N-terminal EF-hand calcium-binding protein 3 (Amyloid-beta A4 protein-binding family A member 2-binding protein) (Nek2-interacting protein 1) (Neuronal calcium-binding protein 3) (X11L-binding protein 51) NECAB3 APBA2BP NIP1 SYTIP2 XB51 Homo sapiens (Human) protein metabolic process [GO:0019538]; protein secretion [GO:0009306]; regulation of amyloid precursor protein biosynthetic process [GO:0042984] cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; Golgi cis cisterna [GO:0000137]; nucleus [GO:0005634] calcium ion binding [GO:0005509] 0.92106 -1.1158 ASKVDQFVTR 0 0 0 0 0 0 0 0 0 10.6892 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96PB1 CASD1_HUMAN N-acetylneuraminate 9-O-acetyltransferase (EC 2.3.1.45) (CAS1 domain-containing protein 1) (Sialate O-acetyltransferase) (SOAT) CASD1 C7orf12 Nbla04196 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975] Golgi membrane [GO:0000139] N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity [GO:0047186] 0.96542 -2.371 EINHYFSVR 8.54782 8.92047 8.84571 0 0 0 0 0 0 0 0 9.49229 0 0 0 0 0 0 0 9.3127 9.91211 0 0 10.449 0 0 10.6287 Q96PC3 AP1S3_HUMAN AP-1 complex subunit sigma-3 (Adaptor protein complex AP-1 subunit sigma-1C) (Adaptor-related protein complex 1 subunit sigma-1C) (Clathrin assembly protein complex 1 sigma-1C small chain) (Golgi adaptor HA1/AP1 adaptin sigma-1C subunit) (Sigma 1C subunit of AP-1 clathrin) (Sigma-adaptin 1C) (Sigma1C-adaptin) AP1S3 Homo sapiens (Human) melanosome assembly [GO:1903232]; platelet dense granule organization [GO:0060155]; protein targeting [GO:0006605]; vesicle-mediated transport [GO:0016192] AP-1 adaptor complex [GO:0030121]; clathrin-coated pit [GO:0005905]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; early endosome [GO:0005769]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; trans-Golgi network membrane [GO:0032588] clathrin adaptor activity [GO:0035615] 0.96792 -2.8894 ELKLVYKR 0 9.86366 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96PC5 MIA2_HUMAN Melanoma inhibitory activity protein 2 (MIA protein 2) (CTAGE family member 5 ER export factor) (Cutaneous T-cell lymphoma-associated antigen 5) (Meningioma-expressed antigen 6/11) MIA2 CTAGE5 MEA11 MEA6 MGEA11 MGEA6 Homo sapiens (Human) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; lipoprotein transport [GO:0042953]; protein exit from endoplasmic reticulum [GO:0032527]; protein localization to endoplasmic reticulum exit site [GO:0070973]; protein secretion [GO:0009306]; vesicle cargo loading [GO:0035459] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] cargo receptor activity [GO:0038024]; enzyme activator activity [GO:0008047] 0.97002 -4.3494 ENAHNRQK 0 9.18237 8.85175 0 10.3372 0 0 0 0 0 0 0 0 0 0 10.0404 0 0 0 0 0 0 0 0 11.5308 0 0 Q96PD7 DGAT2_HUMAN Diacylglycerol O-acyltransferase 2 (EC 2.3.1.20) (Acyl-CoA retinol O-fatty-acyltransferase) (ARAT) (Retinol O-fatty-acyltransferase) (EC 2.3.1.76) (Diglyceride acyltransferase 2) DGAT2 HMFN1045 UNQ738/PRO1433 Homo sapiens (Human) bile acid signaling pathway [GO:0038183]; cellular response to oleic acid [GO:0071400]; cholesterol homeostasis [GO:0042632]; diacylglycerol biosynthetic process [GO:0006651]; diacylglycerol metabolic process [GO:0046339]; fat pad development [GO:0060613]; fatty acid homeostasis [GO:0055089]; glycerol metabolic process [GO:0006071]; intracellular triglyceride homeostasis [GO:0035356]; lipid storage [GO:0019915]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]; low-density lipoprotein particle clearance [GO:0034383]; monoacylglycerol biosynthetic process [GO:0006640]; negative regulation of fatty acid oxidation [GO:0046322]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of cholesterol metabolic process [GO:0090181]; regulation of lipoprotein metabolic process [GO:0050746]; regulation of plasma lipoprotein particle levels [GO:0097006]; triglyceride biosynthetic process [GO:0019432] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; mitochondrion [GO:0005739]; perinuclear endoplasmic reticulum membrane [GO:1990578]; perinuclear region of cytoplasm [GO:0048471] 2-acylglycerol O-acyltransferase activity [GO:0003846]; diacylglycerol O-acyltransferase activity [GO:0004144]; protein homodimerization activity [GO:0042803]; retinol O-fatty-acyltransferase activity [GO:0050252] 0.96419 -2.3835 GERQAEADRSQR 0 0 10.8454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96PE1 AGRA2_HUMAN Adhesion G protein-coupled receptor A2 (G-protein coupled receptor 124) (Tumor endothelial marker 5) ADGRA2 GPR124 KIAA1531 TEM5 Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; central nervous system development [GO:0007417]; endothelial cell migration [GO:0043542]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of vascular endothelial growth factor signaling pathway [GO:1900747]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of endothelial cell migration [GO:0010595]; regulation of angiogenesis [GO:0045765]; regulation of chemotaxis [GO:0050920]; regulation of establishment of blood-brain barrier [GO:0090210]; sprouting angiogenesis [GO:0002040]; Wnt signaling pathway [GO:0016055] cell surface [GO:0009986]; filopodium [GO:0030175]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; plasma membrane [GO:0005886]; Wnt signalosome [GO:1990909] G protein-coupled receptor activity [GO:0004930] 0.92185 -1.1358 GDFRWPR 0 0 0 0 0 0 0 0 10.1198 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96PE2 ARHGH_HUMAN Rho guanine nucleotide exchange factor 17 (164 kDa Rho-specific guanine-nucleotide exchange factor) (p164-RhoGEF) (p164RhoGEF) (Tumor endothelial marker 4) ARHGEF17 KIAA0337 TEM4 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; regulation of small GTPase mediated signal transduction [GO:0051056] cytosol [GO:0005829] guanyl-nucleotide exchange factor activity [GO:0005085] 0.96937 -7.2886 DLTATLRR 9.8566 0 0 0 0 0 0 0 0 0 0 0 9.58856 0 0 0 0 10.5505 0 10.2174 9.60491 0 9.4412 0 0 0 8.7828 Q96PE3 INP4A_HUMAN "Inositol polyphosphate-4-phosphatase type I A (Inositol polyphosphate 4-phosphatase type I) (Type I inositol 3,4-bisphosphate 4-phosphatase) (EC 3.1.3.66)" INPP4A Homo sapiens (Human) inositol phosphate metabolic process [GO:0043647]; phosphatidylinositol biosynthetic process [GO:0006661]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; recycling endosome membrane [GO:0055038] "inositol-1,3,4-trisphosphate 4-phosphatase activity [GO:0017161]; inositol-3,4-bisphosphate 4-phosphatase activity [GO:0052828]; phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity [GO:0016316]" 0.88351 -0.29917 EVLPEDCLPR 0 0 0 0 0 0 0 0 0 0 9.24918 9.13317 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96PE6 ZIM3_HUMAN Zinc finger imprinted 3 (Zinc finger protein 657) ZIM3 ZNF657 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.78618 0.25546 HACQKPFECHSCGRAFGEK 0 0 11.0949 0 0 0 0 11.1257 0 0 0 0 10.6467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96PF1 TGM7_HUMAN Protein-glutamine gamma-glutamyltransferase Z (Transglutaminase Z) (TG(Z)) (TGZ) (TGase Z) (EC 2.3.2.13) (Transglutaminase-7) (TGase-7) TGM7 Homo sapiens (Human) peptide cross-linking [GO:0018149] metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810] 0.9595 -1.8859 AGPRQLQVLISSNEVK 10.0053 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8577 0 0 0 0 0 0 0 0 0 0 Q96PF2 TSSK2_HUMAN Testis-specific serine/threonine-protein kinase 2 (TSK-2) (TSK2) (TSSK-2) (Testis-specific kinase 2) (EC 2.7.11.1) (DiGeorge syndrome protein G) (DGS-G) (Serine/threonine-protein kinase 22B) TSSK2 DGSG SPOGA2 STK22B Homo sapiens (Human) cellular response to glucose starvation [GO:0042149]; intracellular signal transduction [GO:0035556]; negative regulation of TOR signaling [GO:0032007]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; spermatid development [GO:0007286] acrosomal vesicle [GO:0001669]; centriole [GO:0005814]; cytoplasm [GO:0005737]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634] ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein-containing complex binding [GO:0044877] 0.56561 0.50158 LSDFGFSKRCLR 9.50865 9.39421 9.17966 0 9.84235 9.67904 9.27177 9.36737 0 0 0 8.97281 0 0 0 10.3512 0 0 0 0 0 0 0 0 0 10.5773 0 Q96PG8 BBC3B_HUMAN "Bcl-2-binding component 3, isoforms 3/4 (JFY-1) (p53 up-regulated modulator of apoptosis)" BBC3 PUMA Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; execution phase of apoptosis [GO:0097194]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; release of cytochrome c from mitochondria [GO:0001836] mitochondrion [GO:0005739] ATPase binding [GO:0051117] 0.89855 -0.60453 TPGGQLPGAR 9.99124 10.1285 0 0 0 0 0 9.6524 9.50019 9.8279 9.96924 9.96129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96PK6 RBM14_HUMAN RNA-binding protein 14 (Paraspeckle protein 2) (PSP2) (RNA-binding motif protein 14) (RRM-containing coactivator activator/modulator) (Synaptotagmin-interacting protein) (SYT-interacting protein) RBM14 SIP Homo sapiens (Human) "activation of innate immune response [GO:0002218]; centriole assembly [GO:0098534]; innate immune response [GO:0045087]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of centriole replication [GO:0046600]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to hormone [GO:0009725]; SMAD protein signal transduction [GO:0060395]; transcription initiation-coupled chromatin remodeling [GO:0045815]" cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription regulator complex [GO:0005667] nuclear receptor coactivator activity [GO:0030374]; RNA binding [GO:0003723] 0.94665 -1.3514 AQPSVSLGAPYR 0 0 0 0 0 0 0 0 0 8.9128 11.1306 8.92736 0 0 0 0 8.92828 0 0 0 0 0 0 0 0 0 0 Q96PL1 SG3A2_HUMAN Secretoglobin family 3A member 2 (Pneumo secretory protein 1) (PnSP-1) (Uteroglobin-related protein 1) SCGB3A2 PNSP1 UGRP1 UNQ566/PRO1128 Homo sapiens (Human) endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; extracellular space [GO:0005615] 0.84351 0.15187 VPLPVDK 0 0 0 0 0 0 0 0 11.7568 12.6263 12.5879 12.6817 10.2016 0 0 0 0 11.8338 0 10.5581 10.6231 0 11.129 11.0989 0 0 0 Q96PM5 ZN363_HUMAN RING finger and CHY zinc finger domain-containing protein 1 (EC 2.3.2.27) (Androgen receptor N-terminal-interacting protein) (CH-rich-interacting match with PLAG1) (E3 ubiquitin-protein ligase Pirh2) (RING finger protein 199) (RING-type E3 ubiquitin transferase RCHY1) (Zinc finger protein 363) (p53-induced RING-H2 protein) (hPirh2) RCHY1 ARNIP CHIMP PIRH2 RNF199 ZNF363 Homo sapiens (Human) error-free translesion synthesis [GO:0070987]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; rescue of stalled ribosome [GO:0072344]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151] p53 binding [GO:0002039]; protein homodimerization activity [GO:0042803]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.36949 0.7378 KQYHCENCGICR 0 0 9.06859 0 8.71833 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96PN6 ADCYA_HUMAN Adenylate cyclase type 10 (EC 4.6.1.1) (AH-related protein) (Adenylate cyclase homolog) (Germ cell soluble adenylyl cyclase) (hsAC) (sAC) (Testicular soluble adenylyl cyclase) ADCY10 SAC Homo sapiens (Human) cAMP biosynthetic process [GO:0006171]; cellular response to inorganic substance [GO:0071241]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; spermatogenesis [GO:0007283] apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular region [GO:0005576]; growth cone [GO:0030426]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] adenylate cyclase activity [GO:0004016]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; bicarbonate binding [GO:0071890]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145] 0.94129 -1.3148 LNALDMDAIK 9.70895 0 0 0 0 0 9.68769 9.76353 0 0 8.91516 0 0 0 0 10.6825 0 0 0 0 0 0 0 0 0 0 0 Q96PN7 TREF1_HUMAN Transcriptional-regulating factor 1 (Breast cancer anti-estrogen resistance 2) (Transcriptional-regulating protein 132) (Zinc finger protein rapa) (Zinc finger transcription factor TReP-132) TRERF1 BCAR2 RAPA TREP132 Homo sapiens (Human) cellular response to progesterone stimulus [GO:0071393]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; progesterone receptor signaling pathway [GO:0050847]; regulation of transcription by RNA polymerase II [GO:0006357] cytosol [GO:0005829]; fibrillar center [GO:0001650]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] DNA binding [GO:0003677]; metal ion binding [GO:0046872]; nuclear progesterone receptor binding [GO:0033142]; nuclear receptor coactivator activity [GO:0030374]; transcription coactivator activity [GO:0003713]; transcription coactivator binding [GO:0001223]; transcription corepressor activity [GO:0003714] 0.88533 -0.3751 GAIPSGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5065 Q96PP9 GBP4_HUMAN Guanylate-binding protein 4 (EC 3.6.5.-) (GTP-binding protein 4) (GBP-4) (Guanine nucleotide-binding protein 4) GBP4 Homo sapiens (Human) cellular response to type II interferon [GO:0071346]; defense response to Gram-positive bacterium [GO:0050830]; defense response to protozoan [GO:0042832] cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803] 0.065347 1.2898 ISQPVVVVAIVGLYR 10.4261 10.1518 10.5948 9.8083 0 9.90752 9.46365 9.61289 9.63708 9.73833 9.87344 9.54705 8.8041 0 0 9.96867 0 0 0 0 0 0 0 0 0 0 0 Q96PQ0 SORC2_HUMAN VPS10 domain-containing receptor SorCS2 [Cleaved into: SorCS2 122 kDa chain; SorCS2 104 kDa chain; SorCS2 18 kDa chain] SORCS2 KIAA1329 Homo sapiens (Human) intracellular protein transport [GO:0006886]; long-term synaptic depression [GO:0060292]; neuropeptide signaling pathway [GO:0007218] cytosol [GO:0005829]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; perikaryon [GO:0043204]; postsynaptic density membrane [GO:0098839]; recycling endosome membrane [GO:0055038] neuropeptide receptor activity [GO:0008188] 0.97013 -4.2913 APSPGAPPPPR 0 8.72591 0 0 0 9.81903 9.85905 0 0 0 0 0 0 0 10.5275 0 0 0 0 0 10.239 0 9.20055 0 0 0 0 Q96PQ5 IPP2L_HUMAN "Putative protein phosphatase inhibitor 2-like protein 1 (Protein phosphatase 1, regulatory subunit 2 pseudogene 1)" PPP1R2P1 Homo sapiens (Human) glycogen metabolic process [GO:0005977]; regulation of phosphoprotein phosphatase activity [GO:0043666]; regulation of signal transduction [GO:0009966] protein phosphatase inhibitor activity [GO:0004864] 0.79991 0.23919 TLHYNEGLNIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.77629 0 0 0 Q96PQ6 ZN317_HUMAN Zinc finger protein 317 ZNF317 KIAA1588 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.92228 -1.1211 LFVSSVWK 0 0 0 0 0 0 0 0 0 0 0 0 9.68862 0 0 0 0 0 9.75816 0 9.46432 0 0 0 0 0 0 Q96PR1 KCNC2_HUMAN Potassium voltage-gated channel subfamily C member 2 (Shaw-like potassium channel) (Voltage-gated potassium channel Kv3.2) KCNC2 Homo sapiens (Human) action potential [GO:0001508]; cellular response to ammonium ion [GO:0071242]; cellular response to nitric oxide [GO:0071732]; cellular response to toxic substance [GO:0097237]; globus pallidus development [GO:0021759]; nitric oxide-cGMP-mediated signaling pathway [GO:0038060]; optic nerve development [GO:0021554]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; response to amine [GO:0014075]; response to ethanol [GO:0045471]; response to light intensity [GO:0009642]; response to magnesium ion [GO:0032026]; response to nerve growth factor [GO:1990089]; response to organic cyclic compound [GO:0014070] apical plasma membrane [GO:0016324]; axolemma [GO:0030673]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; dendrite [GO:0030425]; dendrite membrane [GO:0032590]; GABA-ergic synapse [GO:0098982]; membrane [GO:0016020]; neuronal cell body membrane [GO:0032809]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; vesicle [GO:0031982]; voltage-gated potassium channel complex [GO:0008076] delayed rectifier potassium channel activity [GO:0005251]; transmembrane transporter binding [GO:0044325]; voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential [GO:0099508]; voltage-gated potassium channel activity [GO:0005249] 0.88275 -0.035871 SVLSGDDSTGSEPPLSPPER 0 0 0 11.129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96PU4 UHRF2_HUMAN E3 ubiquitin-protein ligase UHRF2 (EC 2.3.2.27) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear protein 97) (Nuclear zinc finger protein Np97) (RING finger protein 107) (RING-type E3 ubiquitin transferase UHRF2) (Ubiquitin-like PHD and RING finger domain-containing protein 2) (Ubiquitin-like-containing PHD and RING finger domains protein 2) UHRF2 NIRF RNF107 Homo sapiens (Human) cell cycle [GO:0007049]; cell differentiation [GO:0030154]; negative regulation of gene expression via CpG island methylation [GO:0044027]; protein autoubiquitination [GO:0051865]; protein sumoylation [GO:0016925]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726] heterochromatin [GO:0000792]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721] DNA binding [GO:0003677]; histone binding [GO:0042393]; metal ion binding [GO:0046872]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; SUMO transferase activity [GO:0019789]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.90301 -0.69973 TIDGSKTCTIEDVSRK 0 0 0 0 0 0 0 0 9.4215 0 0 0 0 0 0 0 0 0 9.48844 0 0 0 0 0 0 0 0 Q96PU5 NED4L_HUMAN E3 ubiquitin-protein ligase NEDD4-like (EC 2.3.2.26) (EC 2.3.2.36) (HECT-type E3 ubiquitin transferase NED4L) (NEDD4.2) (Nedd4-2) NEDD4L KIAA0439 NEDL3 Homo sapiens (Human) cell differentiation [GO:0030154]; monoatomic ion transmembrane transport [GO:0034220]; negative regulation of potassium ion transmembrane transport [GO:1901380]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of sodium ion transmembrane transport [GO:1902306]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; positive regulation of caveolin-mediated endocytosis [GO:2001288]; positive regulation of dendrite extension [GO:1903861]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; regulation of dendrite morphogenesis [GO:0048814]; regulation of membrane depolarization [GO:0003254]; regulation of membrane potential [GO:0042391]; regulation of membrane repolarization [GO:0060306]; regulation of monoatomic ion transmembrane transport [GO:0034765]; regulation of potassium ion transmembrane transporter activity [GO:1901016]; regulation of protein stability [GO:0031647]; regulation of sodium ion transmembrane transport [GO:1902305]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular cardiac muscle cell action potential [GO:0086005] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; multivesicular body [GO:0005771]; nucleoplasm [GO:0005654] potassium channel inhibitor activity [GO:0019870]; potassium channel regulator activity [GO:0015459]; sodium channel inhibitor activity [GO:0019871]; sodium channel regulator activity [GO:0017080]; transmembrane transporter binding [GO:0044325]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.88507 -0.23495 LDLPPYETFEDLREK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.36518 0 0 0 9.37136 0 0 0 0 0 0 0 0 0 Q96PU9 ODF3A_HUMAN Outer dense fiber protein 3 (Outer dense fiber of sperm tails protein 3) (Sperm tail protein SHIPPO 1) (Transcript induced in spermiogenesis protein 50) ODF3 SHIPPO1 TISP50 Homo sapiens (Human) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; outer dense fiber [GO:0001520] 0.82055 0.21893 GPIMALYSSPGPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0034 0 0 0 0 0 Q96PV0 SYGP1_HUMAN Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1) SYNGAP1 KIAA1938 Homo sapiens (Human) axonogenesis [GO:0007409]; dendrite development [GO:0016358]; maintenance of postsynaptic specialization structure [GO:0098880]; negative regulation of axonogenesis [GO:0050771]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of Ras protein signal transduction [GO:0046580]; neuron apoptotic process [GO:0051402]; pattern specification process [GO:0007389]; Ras protein signal transduction [GO:0007265]; receptor clustering [GO:0043113]; regulation of GTPase activity [GO:0043087]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of MAPK cascade [GO:0043408]; regulation of synapse structure or activity [GO:0050803]; regulation of synaptic plasticity [GO:0048167]; visual learning [GO:0008542] cytosol [GO:0005829]; dendritic shaft [GO:0043198]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] GTPase activator activity [GO:0005096]; SH3 domain binding [GO:0017124] 0.96953 -4.0874 ELKEVFASWRLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.75606 0 0 0 0 0 0 0 0 Q96PV4 PNMA5_HUMAN Paraneoplastic antigen-like protein 5 (Tumor antigen BJ-HCC-25) PNMA5 KIAA1934 Homo sapiens (Human) positive regulation of apoptotic process [GO:0043065] identical protein binding [GO:0042802] 0.96415 -2.2085 AVHKSPLSVR 0 10.6262 10.7308 9.06218 9.38003 0 0 0 9.63278 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96PV6 LENG8_HUMAN Leukocyte receptor cluster member 8 LENG8 KIAA1932 Homo sapiens (Human) nucleus [GO:0005634]; protein-containing complex [GO:0032991] 0.14236 1.0359 CFTACESEEDK 9.6553 9.0728 0 0 0 0 0 0 0 9.15494 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.9474 0 0 Q96PV7 F193B_HUMAN Protein FAM193B FAM193B IRIZIO KIAA1931 Homo sapiens (Human) cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.88713 -0.34084 VPNSARAAK 0 0 0 0 0 0 0 0 0 0 0 8.24916 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96PX8 SLIK1_HUMAN SLIT and NTRK-like protein 1 (Leucine-rich repeat-containing protein 12) SLITRK1 KIAA1910 LRRC12 UNQ233/PRO266 Homo sapiens (Human) adult behavior [GO:0030534]; axonogenesis [GO:0007409]; homeostatic process [GO:0042592]; multicellular organism growth [GO:0035264]; positive regulation of axonogenesis [GO:0050772]; positive regulation of synapse assembly [GO:0051965]; regulation of presynapse assembly [GO:1905606]; synapse assembly [GO:0007416]; synaptic membrane adhesion [GO:0099560] extracellular region [GO:0005576]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; synapse [GO:0045202] 0.89684 -0.53891 ILILNNNLLR 0 0 13.5499 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96PX9 PKH4B_HUMAN Pleckstrin homology domain-containing family G member 4B (PH domain-containing family G member 4B) PLEKHG4B KIAA1909 Homo sapiens (Human) axon guidance [GO:0007411]; regulation of small GTPase mediated signal transduction [GO:0051056] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; plasma membrane [GO:0005886] guanyl-nucleotide exchange factor activity [GO:0005085] 0.96723 -3.7681 CQHCPLAVGR 9.65216 9.31517 9.11213 10.7716 10.6385 0 9.24208 11.4055 9.11239 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96PY0 K1908_HUMAN Putative uncharacterized protein PSMG3-AS1 (PSMG3 antisense RNA 1) PSMG3-AS1 KIAA1908 Homo sapiens (Human) 0.88439 -0.16072 RHPHSSFPQASSPSSPSRR 0 0 0 0 8.69234 0 0 0 10.5286 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96PY5 FMNL2_HUMAN Formin-like protein 2 (Formin homology 2 domain-containing protein 2) FMNL2 FHOD2 KIAA1902 Homo sapiens (Human) cell migration [GO:0016477]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeleton organization [GO:0007010]; regulation of cell morphogenesis [GO:0022604]; regulation of cell shape [GO:0008360] cytosol [GO:0005829] actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; small GTPase binding [GO:0031267] 0.96988 -5.263 ERKPLENLSDEDRFMMQFSK 9.74143 9.64496 9.69829 0 0 0 10.0455 9.88663 9.96809 10.7275 10.7132 0 0 0 0 0 0 10.6238 9.28997 0 0 10.055 0 0 0 0 0 Q96PY6 NEK1_HUMAN Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) (Renal carcinoma antigen NY-REN-55) NEK1 KIAA1901 Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; cilium assembly [GO:0060271]; protein phosphorylation [GO:0006468] centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentriolar material [GO:0000242] 14-3-3 protein binding [GO:0071889]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713] 0.97001 -5.2108 EAMQNKARAEGHMVYLAR 0 0 0 0 0 0 9.1342 0 0 0 9.05398 0 0 0 0 0 0 0 0 9.66244 0 0 0 0 0 0 0 Q96PZ0 PUS7_HUMAN Pseudouridylate synthase 7 homolog (EC 5.4.99.-) PUS7 KIAA1897 Homo sapiens (Human) mRNA processing [GO:0006397]; mRNA pseudouridine synthesis [GO:1990481]; negative regulation of translation [GO:0017148]; pseudouridine synthesis [GO:0001522]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mesoderm development [GO:2000380]; RNA splicing [GO:0008380]; tRNA pseudouridine synthesis [GO:0031119] nucleus [GO:0005634] enzyme binding [GO:0019899]; pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723] 0.89745 -0.53467 EMLTADNLDIDNMRHK 0 0 0 0 0 0 9.24745 0 0 0 0 0 0 0 0 0 0 13.2098 0 0 0 0 0 0 0 0 0 Q96PZ2 F111A_HUMAN Serine protease FAM111A (EC 3.4.21.-) FAM111A KIAA1895 Homo sapiens (Human) DNA damage response [GO:0006974]; DNA replication [GO:0006260]; negative regulation of viral genome replication [GO:0045071]; protein autoprocessing [GO:0016540]; protein-DNA covalent cross-linking repair [GO:0106300]; proteolysis [GO:0006508]; replication fork processing [GO:0031297] chromatin [GO:0000785]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] peptidase activity [GO:0008233]; single-stranded DNA binding [GO:0003697] 0.92165 -1.1369 GLFILTCR 0 0 0 0 0 0 0 0 0 11.3944 0 9.28251 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96PZ7 CSMD1_HUMAN CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1) CSMD1 KIAA1890 UNQ5952/PRO19863 Homo sapiens (Human) conditioned place preference [GO:1990708]; female gonad development [GO:0008585]; glucose homeostasis [GO:0042593]; male gonad development [GO:0008584]; mammary gland branching involved in pregnancy [GO:0060745]; memory [GO:0007613]; oviduct epithelium development [GO:0035846]; startle response [GO:0001964] membrane [GO:0016020] 0.95889 -1.6972 ADMKWTGKSPVCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.40435 10.6908 0 0 9.3617 0 0 0 0 0 0 10.0692 0 Q96Q04 LMTK3_HUMAN Serine/threonine-protein kinase LMTK3 (EC 2.7.11.1) (Lemur tyrosine kinase 3) LMTK3 KIAA1883 TYKLM3 Homo sapiens (Human) protein phosphorylation [GO:0006468] axon [GO:0030424]; dendrite [GO:0030425]; Golgi membrane [GO:0000139] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.56087 0.53448 ALENGELR 0 0 0 0 0 0 0 0 0 8.30588 8.30611 0 0 0 0 0 0 0 0 0 0 10.0497 0 0 0 0 0 Q96Q05 TPPC9_HUMAN Trafficking protein particle complex subunit 9 (NIK- and IKBKB-binding protein) (Tularik gene 1 protein) TRAPPC9 KIAA1882 NIBP T1 Homo sapiens (Human) cerebral cortex development [GO:0021987]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; neuron differentiation [GO:0030182]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; vesicle coating [GO:0006901]; vesicle tethering [GO:0099022] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; trans-Golgi network [GO:0005802]; TRAPP complex [GO:0030008]; TRAPPII protein complex [GO:1990071] 0.92386 -1.0155 EAVAACQVGDPVR 9.70931 0 9.96723 0 0 0 0 9.0124 0 10.8842 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96Q07 BTBD9_HUMAN BTB/POZ domain-containing protein 9 BTBD9 KIAA1880 Homo sapiens (Human) "adult locomotory behavior [GO:0008344]; circadian behavior [GO:0048512]; circadian sleep/wake cycle, non-REM sleep [GO:0042748]; long-term memory [GO:0007616]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal-level iron ion homeostasis [GO:0060586]; regulation of synaptic vesicle endocytosis [GO:1900242]; sensory perception of temperature stimulus [GO:0050951]; serotonin metabolic process [GO:0042428]" cytoplasm [GO:0005737]; glutamatergic synapse [GO:0098978] 0.78535 0.25897 IVGTHNTVNK 8.80096 0 0 9.11866 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96Q15 SMG1_HUMAN Serine/threonine-protein kinase SMG1 (SMG-1) (hSMG-1) (EC 2.7.11.1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (Nonsense mediated mRNA decay-associated PI3K-related kinase SMG1) SMG1 ATX KIAA0421 LIP Homo sapiens (Human) "DNA damage response [GO:0006974]; DNA repair [GO:0006281]; mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine phosphorylation [GO:0018105]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of telomere maintenance [GO:0032204]" chromatoid body [GO:0033391]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein kinase C activity [GO:0004697]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; RNA binding [GO:0003723]; telomeric DNA binding [GO:0042162] 0.96869 -10.194 ALATKDMR 0 0 9.13935 0 0 10.4468 0 0 0 0 0 0 0 10.8015 0 10.4065 9.83441 9.55635 10.4456 9.43225 0 10.3641 0 0 0 9.53411 10.5792 Q96Q35 FACC1_HUMAN Flagellum-associated coiled-coil domain-containing protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein) FLACC1 ALS2CR12 Homo sapiens (Human) cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; outer dense fiber [GO:0001520]; sperm flagellum [GO:0036126] 0.96947 -6.5375 LEEMGKEYK 0 0 0 0 0 0 0 0 0 9.01156 0 0 0 0 0 0 0 0 0 0 0 0 0 9.95629 0 0 0 Q96Q40 CDK15_HUMAN Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein) (Cell division protein kinase 15) (Serine/threonine-protein kinase ALS2CR7) (Serine/threonine-protein kinase PFTAIRE-2) CDK15 ALS2CR7 PFTK2 Homo sapiens (Human) protein phosphorylation [GO:0006468]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; metal ion binding [GO:0046872]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.89685 -0.52526 LGEGSYATVYK 0 0 0 0 0 0 0 0 0 0 0 0 0 8.67642 0 0 0 0 0 0 0 0 0 0 11.0086 0 0 Q96Q42 ALS2_HUMAN Alsin (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein) (Amyotrophic lateral sclerosis 2 protein) ALS2 ALS2CR6 KIAA1563 Homo sapiens (Human) "axonogenesis [GO:0007409]; behavioral fear response [GO:0001662]; cell death [GO:0008219]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; in utero embryonic development [GO:0001701]; locomotory behavior [GO:0007626]; lysosomal transport [GO:0007041]; neuromuscular junction development [GO:0007528]; neuron projection morphogenesis [GO:0048812]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of Rac protein signal transduction [GO:0035022]; protein homooligomerization [GO:0051260]; protein localization [GO:0008104]; Rac protein signal transduction [GO:0016601]; receptor recycling [GO:0001881]; regulation of endosome size [GO:0051036]; regulation of GTPase activity [GO:0043087]; response to oxidative stress [GO:0006979]; synaptic transmission, glutamatergic [GO:0035249]" centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; growth cone [GO:0030426]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; vesicle [GO:0031982] GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activator activity [GO:0043539]; small GTPase binding [GO:0031267] 0.88298 -0.26748 AISQAVDQALR 0 0 0 0 0 0 0 0 0 0 10.9346 9.28098 0 0 0 9.18093 0 0 0 0 0 0 0 0 0 0 0 Q96Q83 ALKB3_HUMAN Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 (EC 1.14.11.33) (EC 1.14.11.54) (Alkylated DNA repair protein alkB homolog 3) (hABH3) (DEPC-1) (Prostate cancer antigen 1) ALKBH3 ABH3 DEPC1 Homo sapiens (Human) cell population proliferation [GO:0008283]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553] cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; L-ascorbic acid binding [GO:0031418]; mRNA N1-methyladenosine dioxygenase activity [GO:1990930]; oxidative DNA demethylase activity [GO:0035516]; oxidative RNA demethylase activity [GO:0035515] 0.95454 -1.5058 EFVFKEPQQVVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.36584 0 0 0 0 0 0 0 0 0 0 0 Q96Q89 KI20B_HUMAN Kinesin-like protein KIF20B (Cancer/testis antigen 90) (CT90) (Kinesin family member 20B) (Kinesin-related motor interacting with PIN1) (M-phase phosphoprotein 1) (MPP1) KIF20B KRMP1 MPHOSPH1 Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; microtubule-based movement [GO:0007018]; neural tube closure [GO:0001843]; neuron projection morphogenesis [GO:0048812]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of mitotic cytokinetic process [GO:1903438]; positive regulation of neuron migration [GO:2001224]; protein localization to microtubule [GO:0035372]; regulation of cell cycle [GO:0051726]; regulation of establishment of cell polarity [GO:2000114]; regulation of mitotic nuclear division [GO:0007088] centrosome [GO:0005813]; contractile ring [GO:0070938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; intercellular bridge [GO:0045171]; kinesin complex [GO:0005871]; microtubule [GO:0005874]; midbody [GO:0030496]; mitotic spindle midzone [GO:1990023]; mitotic spindle pole [GO:0097431]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; spindle midzone [GO:0051233] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777]; plus-end-directed microtubule motor activity [GO:0008574]; protein homodimerization activity [GO:0042803]; WW domain binding [GO:0050699] 0.96861 -10.21 DLNVKELKLK 0 0 0 0 16.2025 10.2199 0 0 0 0 10.8827 9.72148 11.5013 0 0 0 10.5779 0 11.1306 9.33517 0 0 0 0 9.39019 0 0 Q96Q91 B3A4_HUMAN Anion exchange protein 4 (AE 4) (Anion exchanger 4) (Sodium bicarbonate cotransporter 5) (Solute carrier family 4 member 9) SLC4A9 AE4 SBC5 Homo sapiens (Human) bicarbonate transport [GO:0015701]; regulation of intracellular pH [GO:0051453]; transmembrane transport [GO:0055085] apical part of cell [GO:0045177]; basolateral plasma membrane [GO:0016323]; plasma membrane [GO:0005886] monoatomic anion transmembrane transporter activity [GO:0008509]; sodium:bicarbonate symporter activity [GO:0008510]; solute:inorganic anion antiporter activity [GO:0005452] 0.2 0.92025 NPVVLGSLTEVSLPSR 12.6766 12.5377 13.5738 11.5105 10.8455 11.8857 11.997 11.56 12.0636 13.8638 15.4238 15.4163 10.5558 10.7489 10.8011 11.2423 11.6878 11.6069 0 0 0 0 0 10.8133 0 0 0 Q96QB1 RHG07_HUMAN Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein) (DLC-1) (HP protein) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12) DLC1 ARHGAP7 KIAA1723 STARD12 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; focal adhesion assembly [GO:0048041]; forebrain development [GO:0030900]; heart morphogenesis [GO:0003007]; hindbrain morphogenesis [GO:0021575]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; neural tube closure [GO:0001843]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] caveola [GO:0005901]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; membrane raft [GO:0045121]; nucleus [GO:0005634]; ruffle membrane [GO:0032587] GTPase activator activity [GO:0005096]; lipid binding [GO:0008289]; SH2 domain binding [GO:0042169] 0.56028 0.53352 DGPSPGGTLMDLSER 0 0 0 8.96206 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96QC0 PP1RA_HUMAN Serine/threonine-protein phosphatase 1 regulatory subunit 10 (MHC class I region proline-rich protein CAT53) (PP1-binding protein of 114 kDa) (Phosphatase 1 nuclear targeting subunit) (Protein FB19) (p99) PPP1R10 CAT53 FB19 PNUTS Homo sapiens (Human) negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of mitotic DNA damage checkpoint [GO:1904290]; positive regulation of telomere maintenance [GO:0032206]; protein import into nucleus [GO:0006606] chromatin [GO:0000785]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PTW/PP1 phosphatase complex [GO:0072357] DNA binding [GO:0003677]; metal ion binding [GO:0046872]; protein phosphatase 1 binding [GO:0008157]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723] 0.88423 -0.14026 LLGPPPPPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.65456 0 0 0 0 0 0 Q96QD5 DEPD7_HUMAN DEP domain-containing protein 7 (Protein TR2/D15) DEPDC7 Homo sapiens (Human) intracellular signal transduction [GO:0035556] 0.83678 0.19315 LLDFQNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.48583 Q96QD9 UIF_HUMAN UAP56-interacting factor (Forty-two-three domain-containing protein 1) (Protein 40-2-3) FYTTD1 UIF Homo sapiens (Human) mRNA export from nucleus [GO:0006406] nuclear speck [GO:0016607]; nucleoplasm [GO:0005654] mRNA binding [GO:0003729]; RNA binding [GO:0003723] 0.96248 -2.1704 IDMSLDDIIKLNR 10.4009 0 13.3697 0 0 0 0 0 10.3492 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96QE3 ATAD5_HUMAN ATPase family AAA domain-containing protein 5 (Chromosome fragility-associated gene 1 protein) ATAD5 C17orf41 Elg1 FRAG1 Homo sapiens (Human) cell population proliferation [GO:0008283]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; isotype switching [GO:0045190]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; nuclear DNA replication [GO:0033260]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell cycle G2/M phase transition [GO:1902751]; positive regulation of DNA replication [GO:0045740]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; regulation of mitotic cell cycle phase transition [GO:1901990]; signal transduction in response to DNA damage [GO:0042770] Elg1 RFC-like complex [GO:0031391]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA binding [GO:0003677]; DNA clamp unloader activity [GO:0061860] 0.96052 -1.988 ETVNTLAADFP 0 0 0 0 0 0 0 0 0 9.72247 12.9111 0 9.62416 0 0 0 0 0 0 0 0 9.34975 0 0 0 0 0 Q96QE4 LR37B_HUMAN Leucine-rich repeat-containing protein 37B (C66 SLIT-like testicular protein) LRRC37B Homo sapiens (Human) membrane [GO:0016020] 0.81556 0.22102 LPEVVPLLNR 0 0 0 0 0 0 0 0 0 11.5755 0 0 0 0 0 9.11559 0 0 0 0 0 0 0 0 9.62145 0 0 Q96QF7 GCNA_HUMAN Germ cell nuclear acidic protein (Acidic repeat-containing protein) (Germ cell nuclear acidic peptidase) (Germ cell nuclear antigen) GCNA ACRC Homo sapiens (Human) protein-DNA covalent cross-linking repair [GO:0106300] chromosome [GO:0005694]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605] SUMO polymer binding [GO:0032184] 0.95311 -1.483 TKNIVEPPR 0 0 0 0 0 0 0 0 0 0 0 9.18725 0 0 0 0 0 0 0 0 0 0 0 0 9.19734 0 0 Q96QH8 LYZL5_HUMAN Sperm acrosome-associated protein 5 (EC 3.2.1.17) (Lysozyme-like protein 5) (Sperm-specific lysozyme-like protein X) (SLLP-X) SPACA5 LYZL5 SPACA5A UNQ6288/PRO20753; SPACA5B Homo sapiens (Human) fusion of sperm to egg plasma membrane involved in single fertilization [GO:0007342]; metabolic process [GO:0008152] acrosomal vesicle [GO:0001669]; extracellular region [GO:0005576]; sperm flagellum [GO:0036126] lysozyme activity [GO:0003796] 0.9053 -0.72674 IYERCELAAR 0 0 0 0 0 0 0 0 0 0 0 11.8865 0 10.8977 10.8116 11.5982 0 12.3409 0 0 0 0 0 0 0 0 0 Q96QI5 HS3S6_HUMAN Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (3-OST-6) (Heparan sulfate 3-O-sulfotransferase 6) (h3-OST-6) HS3ST6 HS3ST5 Homo sapiens (Human) "blastocyst hatching [GO:0001835]; heparan sulfate proteoglycan biosynthetic process, enzymatic modification [GO:0015015]" Golgi membrane [GO:0000139] [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity [GO:0008467] 0.88753 -0.36005 EAPRRIHAMSPDTK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.3844 0 10.3488 0 0 0 0 0 0 0 0 0 0 0 Q96QK1 VPS35_HUMAN Vacuolar protein sorting-associated protein 35 (hVPS35) (Maternal-embryonic 3) (Vesicle protein sorting 35) VPS35 MEM3 TCCCTA00141 Homo sapiens (Human) "endocytic recycling [GO:0032456]; intracellular protein transport [GO:0006886]; lysosome organization [GO:0007040]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrion to lysosome transport [GO:0099074]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of cell death [GO:0060548]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of late endosome to lysosome transport [GO:1902823]; negative regulation of lysosomal protein catabolic process [GO:1905166]; negative regulation of neuron death [GO:1901215]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of protein localization [GO:1903828]; neurotransmitter receptor transport, endosome to plasma membrane [GO:0099639]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of dopamine receptor signaling pathway [GO:0060161]; positive regulation of gene expression [GO:0010628]; positive regulation of locomotion involved in locomotory behavior [GO:0090326]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of Wnt protein secretion [GO:0061357]; protein destabilization [GO:0031648]; protein localization to endosome [GO:0036010]; regulation of dendritic spine maintenance [GO:1902950]; regulation of macroautophagy [GO:0016241]; regulation of mitochondrion organization [GO:0010821]; regulation of postsynapse assembly [GO:0150052]; regulation of presynapse assembly [GO:1905606]; regulation of protein metabolic process [GO:0051246]; regulation of protein stability [GO:0031647]; regulation of synapse maturation [GO:0090128]; regulation of terminal button organization [GO:2000331]; retrograde transport, endosome to Golgi [GO:0042147]; transcytosis [GO:0045056]; vesicle-mediated transport in synapse [GO:0099003]; voluntary musculoskeletal movement [GO:0050882]; Wnt signaling pathway [GO:0016055]" "cytosol [GO:0005829]; dopaminergic synapse [GO:0098691]; early endosome [GO:0005769]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; mitochondrion-derived vesicle [GO:0099073]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; retromer complex [GO:0030904]; retromer, cargo-selective complex [GO:0030906]; tubular endosome [GO:0097422]" D1 dopamine receptor binding [GO:0031748] 0 2.8093 AELAELPLR 0 0 0 0 0 0 0 0 0 0 0 9.97699 0 0 0 0 0 0 0 0 0 0 0 0 0 8.98319 0 Q96QS6 KPSH2_HUMAN Serine/threonine-protein kinase H2 (EC 2.7.11.1) (Protein serine kinase H2) (PSK-H2) PSKH2 Homo sapiens (Human) protein phosphorylation [GO:0006468] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.92387 -1.0445 ASPHSQSPGSAQSSK 9.09437 11.9299 0 9.50609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5618 Q96QT4 TRPM7_HUMAN Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Channel-kinase 1) (Long transient receptor potential channel 7) (LTrpC-7) (LTrpC7) TRPM7 CHAK1 LTRPC7 Homo sapiens (Human) actomyosin structure organization [GO:0031032]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; calcium-dependent cell-matrix adhesion [GO:0016340]; monoatomic cation transmembrane transport [GO:0098655]; necroptotic process [GO:0070266]; protein autophosphorylation [GO:0046777]; protein tetramerization [GO:0051262] plasma membrane [GO:0005886]; ruffle [GO:0001726] actin binding [GO:0003779]; ATP binding [GO:0005524]; calcium channel activity [GO:0005262]; metal ion binding [GO:0046872]; myosin binding [GO:0017022]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.89899 -0.60283 IDTVMEEGK 9.10148 0 10.2187 0 0 0 0 8.72516 0 0 0 0 8.26973 0 0 8.67892 0 0 0 0 0 0 0 0 0 0 0 Q96QU1 PCD15_HUMAN Protocadherin-15 PCDH15 USH1F Homo sapiens (Human) cell adhesion [GO:0007155]; equilibrioception [GO:0050957]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear development [GO:0048839]; photoreceptor cell maintenance [GO:0045494]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605] extracellular region [GO:0005576]; extracellular space [GO:0005615]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; stereocilium [GO:0032420]; synapse [GO:0045202] calcium ion binding [GO:0005509] 0.90223 -0.69807 IEDLTEILDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7881 0 0 0 10.6441 0 0 0 0 0 0 Q96QU8 XPO6_HUMAN Exportin-6 (Exp6) (Ran-binding protein 20) XPO6 KIAA0370 RANBP20 Homo sapiens (Human) protein export from nucleus [GO:0006611] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] nuclear export signal receptor activity [GO:0005049]; small GTPase binding [GO:0031267] 0.96994 -4.3597 FTDFLRLFVSVHLRR 0 0 0 0 0 0 0 10.3906 0 0 0 0 12.4263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96QV1 HHIP_HUMAN Hedgehog-interacting protein (HHIP) (HIP) HHIP HIP UNQ5825/PRO19644 Homo sapiens (Human) dorsal/ventral pattern formation [GO:0009953]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; negative regulation of apoptotic process [GO:0043066]; negative regulation of signal transduction [GO:0009968]; negative regulation of smoothened signaling pathway [GO:0045879]; neuroblast proliferation [GO:0007405]; regulation of fibroblast growth factor receptor signaling pathway [GO:0040036]; signal transduction [GO:0007165]; skeletal system morphogenesis [GO:0048705] cell surface [GO:0009986]; ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886] hedgehog family protein binding [GO:0097108]; zinc ion binding [GO:0008270] 0.95065 -1.4171 EVLERDLVLPLLCK 0 0 0 12.0505 12.0807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96QZ0 PANX3_HUMAN Pannexin-3 PANX3 Homo sapiens (Human) cell-cell signaling [GO:0007267]; monoatomic cation transport [GO:0006812]; positive regulation of interleukin-1 production [GO:0032732] gap junction [GO:0005921]; plasma membrane [GO:0005886] channel activity [GO:0015267]; structural molecule activity [GO:0005198] 0.94579 -1.341 QDGPGQDKMKSLWPHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.68284 0 0 0 0 0 0 0 Q96QZ7 MAGI1_HUMAN "Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (Atrophin-1-interacting protein 3) (AIP-3) (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Trinucleotide repeat-containing gene 19 protein) (WW domain-containing protein 3) (WWP3)" MAGI1 AIP3 BAIAP1 BAP1 TNRC19 Homo sapiens (Human) cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; positive regulation of cell-cell adhesion [GO:0022409]; protein-containing complex assembly [GO:0065003]; signal transduction [GO:0007165] adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] alpha-actinin binding [GO:0051393]; ATP binding [GO:0005524] 0.96942 -4.4277 AAAANGPK 10.619 14.5791 9.40269 0 13.1371 0 12.1775 12.6757 8.07628 11.6774 0 0 0 0 0 11.1624 0 0 9.75298 9.52284 0 0 0 0 0 9.7185 9.89913 Q96R06 SPAG5_HUMAN Sperm-associated antigen 5 (Astrin) (Deepest) (Mitotic spindle-associated protein p126) (MAP126) SPAG5 Homo sapiens (Human) cell division [GO:0051301]; chromosome segregation [GO:0007059]; establishment of spindle orientation [GO:0051294]; mitotic sister chromatid segregation [GO:0000070]; positive regulation of intracellular transport [GO:0032388]; positive regulation of spindle assembly [GO:1905832]; protein localization to centrosome [GO:0071539]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of metaphase plate congression [GO:0090235]; spindle organization [GO:0007051] centriolar satellite [GO:0034451]; ciliary basal body [GO:0036064]; ciliary rootlet [GO:0035253]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; microtubule plus-end [GO:0035371]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; mitotic spindle pole [GO:0097431]; nuclear body [GO:0016604] microtubule binding [GO:0008017] 0.8337 0.19976 ISQLEQDLASMR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.98251 0 0 0 0 0 Q96R30 OR2V2_HUMAN Olfactory receptor 2V2 (Olfactory receptor 2V3) (Olfactory receptor OR5-3) OR2V2 OR2V3 Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of smell [GO:0050911] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.79887 0.23967 LACVDTSLFEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.283 0 0 0 0 0 0 0 0 0 Q96R72 OR4K3_HUMAN Olfactory receptor 4K3 (Olfactory receptor OR14-14) OR4K3 OR4K3P Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.64974 0.39598 SSGGSSK 0 0 0 0 0 0 0 0 0 0 0 0 0 8.73495 0 10.7348 11.0936 10.9325 0 0 0 0 0 0 0 0 0 Q96RD3 O52E6_HUMAN Olfactory receptor 52E6 (Olfactory receptor OR11-58) OR52E6 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.95282 -1.4638 IFFKTDH 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.29875 9.75069 0 0 0 0 0 Q96RD6 PANX2_HUMAN Pannexin-2 PANX2 Homo sapiens (Human) monoatomic cation transport [GO:0006812]; positive regulation of interleukin-1 production [GO:0032732]; response to ischemia [GO:0002931] cytoplasm [GO:0005737]; gap junction [GO:0005921]; plasma membrane [GO:0005886] channel activity [GO:0015267]; structural molecule activity [GO:0005198] 0.86498 0.084841 DQALYARGYCWTELR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.25701 0 0 0 0 0 0 0 0 0 0 0 Q96RD7 PANX1_HUMAN Pannexin-1 PANX1 MRS1 UNQ2529/PRO6028 Homo sapiens (Human) calcium ion transport [GO:0006816]; cell-cell signaling [GO:0007267]; monoatomic cation transport [GO:0006812]; oogenesis [GO:0048477]; positive regulation of interleukin-1 alpha production [GO:0032730]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of macrophage cytokine production [GO:0060907]; response to ATP [GO:0033198]; response to ischemia [GO:0002931] bleb [GO:0032059]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; gap junction [GO:0005921]; membrane [GO:0016020]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] actin filament binding [GO:0051015]; calcium channel activity [GO:0005262]; gap junction channel activity [GO:0005243]; identical protein binding [GO:0042802]; leak channel activity [GO:0022840]; protease binding [GO:0002020]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; transmembrane transporter binding [GO:0044325] 0.61402 0.42399 FAAAPHICSDLK 0 0 10.9299 8.8828 9.26155 0 10.651 10.8643 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96RD9 FCRL5_HUMAN Fc receptor-like protein 5 (FcR-like protein 5) (FcRL5) (BXMAS1) (Fc receptor homolog 5) (FcRH5) (Immune receptor translocation-associated protein 2) (CD antigen CD307e) FCRL5 FCRH5 IRTA2 UNQ503/PRO820 Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; single fertilization [GO:0007338] cell surface [GO:0009986]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] transmembrane signaling receptor activity [GO:0004888] 0.89004 -0.4832 GENVVYSEVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5719 Q96RE7 NACC1_HUMAN Nucleus accumbens-associated protein 1 (NAC-1) (BTB/POZ domain-containing protein 14B) NACC1 BTBD14B NAC1 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; regulation of transcription by RNA polymerase II [GO:0006357] cell junction [GO:0030054]; cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; histone deacetylase binding [GO:0042826]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.81949 0.21926 LYDEGDPSEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.8959 0 0 0 0 0 0 0 0 0 Q96RE9 ZN300_HUMAN Zinc finger protein 300 ZNF300 Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944] nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]" 0.86863 0.071855 GVTRDGSLCSILK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.75201 9.75096 0 Q96RG2 PASK_HUMAN PAS domain-containing serine/threonine-protein kinase (PAS-kinase) (PASKIN) (hPASK) (EC 2.7.11.1) PASK KIAA0135 Homo sapiens (Human) energy homeostasis [GO:0097009]; intracellular signal transduction [GO:0035556]; negative regulation of glycogen biosynthetic process [GO:0045719]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of glucagon secretion [GO:0070092]; regulation of respiratory gaseous exchange [GO:0043576] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] ATP binding [GO:0005524]; phosphatidylinositol binding [GO:0035091]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.76494 0.28652 AIFTVDAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.43993 0 0 8.51318 0 0 0 9.74819 10.1109 Q96RK0 CIC_HUMAN Protein capicua homolog CIC KIAA0306 Homo sapiens (Human) brain development [GO:0007420]; learning [GO:0007612]; memory [GO:0007613]; negative regulation of DNA-templated transcription [GO:0045892]; regulation of transcription by RNA polymerase II [GO:0006357]; social behavior [GO:0035176] chromatin [GO:0000785]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.88151 -0.30436 EAHFKAHPDWK 0 0 0 0 0 0 0 0 0 0 0 9.31302 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96RK4 BBS4_HUMAN Bardet-Biedl syndrome 4 protein BBS4 Homo sapiens (Human) adult behavior [GO:0030534]; brain morphogenesis [GO:0048854]; centrosome cycle [GO:0007098]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; dendrite development [GO:0016358]; face development [GO:0060324]; fat cell differentiation [GO:0045444]; fat pad development [GO:0060613]; gene expression [GO:0010467]; heart looping [GO:0001947]; hippocampus development [GO:0021766]; intracellular transport [GO:0046907]; maintenance of protein location in nucleus [GO:0051457]; melanosome transport [GO:0032402]; microtubule anchoring at centrosome [GO:0034454]; microtubule cytoskeleton organization [GO:0000226]; mitotic cytokinesis [GO:0000281]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of appetite by leptin-mediated signaling pathway [GO:0038108]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of systemic arterial blood pressure [GO:0003085]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; photoreceptor cell outer segment organization [GO:0035845]; positive regulation of cilium assembly [GO:0045724]; positive regulation of multicellular organism growth [GO:0040018]; protein localization to centrosome [GO:0071539]; protein localization to cilium [GO:0061512]; protein localization to organelle [GO:0033365]; protein localization to photoreceptor outer segment [GO:1903546]; protein transport [GO:0015031]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296]; regulation of cytokinesis [GO:0032465]; regulation of lipid metabolic process [GO:0019216]; regulation of non-motile cilium assembly [GO:1902855]; regulation of stress fiber assembly [GO:0051492]; retina homeostasis [GO:0001895]; retinal rod cell development [GO:0046548]; sensory perception of smell [GO:0007608]; sensory processing [GO:0050893]; social behavior [GO:0035176]; spermatid development [GO:0007286]; striatum development [GO:0021756]; ventricular system development [GO:0021591]; visual perception [GO:0007601] BBSome [GO:0034464]; centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary membrane [GO:0060170]; ciliary transition zone [GO:0035869]; cilium [GO:0005929]; cytosol [GO:0005829]; motile cilium [GO:0031514]; non-motile cilium [GO:0097730]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; photoreceptor connecting cilium [GO:0032391]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750] alpha-tubulin binding [GO:0043014]; beta-tubulin binding [GO:0048487]; dynactin binding [GO:0034452]; protein-macromolecule adaptor activity [GO:0030674]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629] 0.91562 -0.76335 RAYAEAVHLDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.65195 0 0 0 0 0 0 0 0 Q96RL1 UIMC1_HUMAN BRCA1-A complex subunit RAP80 (Receptor-associated protein 80) (Retinoid X receptor-interacting protein 110) (Ubiquitin interaction motif-containing protein 1) UIMC1 RAP80 RXRIP110 Homo sapiens (Human) chromatin organization [GO:0006325]; double-strand break repair [GO:0006302]; histone H2A K63-linked deubiquitination [GO:0070537]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; mitotic G2/M transition checkpoint [GO:0044818]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of DNA repair [GO:0045739]; regulation of DNA repair [GO:0006282]; response to ionizing radiation [GO:0010212] BRCA1-A complex [GO:0070531]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861] DNA binding [GO:0003677]; histone binding [GO:0042393]; K63-linked polyubiquitin modification-dependent protein binding [GO:0070530]; metal ion binding [GO:0046872]; ubiquitin modification-dependent histone binding [GO:0061649] 0.96875 -8.2084 AKCLAKR 0 0 0 0 9.03348 0 0 0 0 0 13.269 10.0946 0 0 0 0 0 0 0 9.63398 0 0 0 0 0 0 0 Q96RL7 VP13A_HUMAN Intermembrane lipid transfer protein VPS13A (Chorea-acanthocytosis protein) (Chorein) (Vacuolar protein sorting-associated protein 13A) VPS13A CHAC KIAA0986 Homo sapiens (Human) autophagy [GO:0006914]; flagellated sperm motility [GO:0030317]; Golgi to endosome transport [GO:0006895]; lipid transport [GO:0006869]; locomotory behavior [GO:0007626]; lysosomal protein catabolic process [GO:1905146]; nervous system development [GO:0007399]; protein localization [GO:0008104]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; social behavior [GO:0035176]; sperm mitochondrion organization [GO:0030382] cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lipid droplet [GO:0005811]; lysosomal membrane [GO:0005765]; mitochondria-associated endoplasmic reticulum membrane [GO:0044233]; mitochondrial membrane [GO:0031966]; mitochondrial outer membrane [GO:0005741]; neuronal dense core vesicle lumen [GO:0099013]; sperm midpiece [GO:0097225] 0.96957 -5.4766 DMMDIKYR 0 0 0 0 0 0 8.78247 0 0 10.178 9.37321 0 0 10.4321 8.58931 0 11.143 0 0 0 0 0 0 0 9.99845 0 0 Q96RM1 SPR2F_HUMAN Small proline-rich protein 2F (SPR-2F) SPRR2F Homo sapiens (Human) epidermis development [GO:0008544]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216] cornified envelope [GO:0001533]; cytosol [GO:0005829] 0.82163 0.21701 QPCQPPPVCPAPKCPEPCPPPK 0 10.7514 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96RN1 S26A8_HUMAN Testis anion transporter 1 (Anion exchange transporter) (Solute carrier family 26 member 8) SLC26A8 TAT1 Homo sapiens (Human) cell differentiation [GO:0030154]; chloride transport [GO:0006821]; meiotic cell cycle [GO:0051321]; oxalate transport [GO:0019532]; spermatogenesis [GO:0007283]; sulfate transport [GO:0008272] plasma membrane [GO:0005886] bicarbonate transmembrane transporter activity [GO:0015106]; chloride channel activity [GO:0005254]; chloride transmembrane transporter activity [GO:0015108]; oxalate transmembrane transporter activity [GO:0019531]; sulfate transmembrane transporter activity [GO:0015116] 0.95448 -1.5089 ETYSETDKNDNSR 0 12.7929 0 8.66803 11.3812 11.258 12.3321 0 12.4267 0 0 0 0 0 0 11.1653 0 10.8546 0 0 0 0 0 0 0 0 0 Q96RN5 MED15_HUMAN Mediator of RNA polymerase II transcription subunit 15 (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a) (Mediator complex subunit 15) (Positive cofactor 2 glutamine/Q-rich-associated protein) (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Trinucleotide repeat-containing gene 7 protein) MED15 ARC105 CTG7A PCQAP TIG1 TNRC7 Homo sapiens (Human) positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; RNA polymerase II preinitiation complex assembly [GO:0051123]; somatic stem cell population maintenance [GO:0035019] core mediator complex [GO:0070847]; cytoplasm [GO:0005737]; mediator complex [GO:0016592]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] transcription coregulator activity [GO:0003712] 0.88479 -0.28582 SSKDMESHVFLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.6699 0 0 0 0 0 Q96RP7 G3ST4_HUMAN "Galactose-3-O-sulfotransferase 4 (Gal3ST-4) (EC 2.8.2.-) (Beta-galactose-3-O-sulfotransferase 4) (Gal-beta-1,3-GalNAc 3'-sulfotransferase)" GAL3ST4 PP6968 Homo sapiens (Human) cell-cell signaling [GO:0007267]; glycolipid biosynthetic process [GO:0009247]; glycoprotein biosynthetic process [GO:0009101]; glycoprotein metabolic process [GO:0009100]; oligosaccharide metabolic process [GO:0009311]; proteoglycan biosynthetic process [GO:0030166]; sulfur compound metabolic process [GO:0006790] extracellular exosome [GO:0070062]; Golgi cisterna membrane [GO:0032580]; membrane [GO:0016020] 3'-phosphoadenosine 5'-phosphosulfate binding [GO:0050656]; galactose 3-O-sulfotransferase activity [GO:0050694]; galactosylceramide sulfotransferase activity [GO:0001733]; proteoglycan sulfotransferase activity [GO:0050698]; sulfotransferase activity [GO:0008146] 0.92422 -1.0311 LQTAVAELR 0 0 0 0 0 0 0 0 0 0 0 0 0 8.94743 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96RP9 EFGM_HUMAN "Elongation factor G, mitochondrial (EF-Gmt) (Elongation factor G 1, mitochondrial) (mEF-G 1) (Elongation factor G1) (hEFG1)" GFM1 EFG EFG1 GFM Homo sapiens (Human) mitochondrial translational elongation [GO:0070125] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; RNA binding [GO:0003723]; translation elongation factor activity [GO:0003746] 0.96371 -2.2144 DNSHPFVGLAFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0391 10.2353 Q96RQ1 ERGI2_HUMAN Endoplasmic reticulum-Golgi intermediate compartment protein 2 ERGIC2 ERV41 PTX1 CDA14 Homo sapiens (Human) "endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]" "COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; retrograde transporter complex, Golgi to ER [GO:0061852]; transporter complex [GO:1990351]" 0.84332 0.17648 ISADTHQFSVTER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1482 0 0 0 0 0 0 Q96RQ3 MCCA_HUMAN "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (MCCase subunit alpha) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (3-methylcrotonyl-CoA carboxylase biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha)" MCCC1 MCCA Homo sapiens (Human) biotin metabolic process [GO:0006768]; branched-chain amino acid catabolic process [GO:0009083]; leucine catabolic process [GO:0006552] "3-methylcrotonyl-CoA carboxylase complex, mitochondrial [GO:0002169]; cytosol [GO:0005829]; methylcrotonoyl-CoA carboxylase complex [GO:1905202]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]" ATP binding [GO:0005524]; biotin binding [GO:0009374]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; methylcrotonoyl-CoA carboxylase activity [GO:0004485] 0.96577 -2.3635 KLGVQTVAVYSEADR 0 0 0 0 0 0 0 10.0312 0 0 0 0 0 0 0 0 10.629 0 0 0 0 10.9347 0 0 0 11.3176 0 Q96RR1 PEO1_HUMAN "Twinkle mtDNA helicase (EC 3.6.4.12) (Progressive external ophthalmoplegia 1 protein) (T7 gp4-like protein with intramitochondrial nucleoid localization) (T7-like mitochondrial DNA helicase) (Twinkle protein, mitochondrial)" TWNK C10orf2 PEO1 Homo sapiens (Human) cellular response to glucose stimulus [GO:0071333]; DNA unwinding involved in DNA replication [GO:0006268]; mitochondrial DNA replication [GO:0006264]; mitochondrial transcription [GO:0006390]; protein hexamerization [GO:0034214] mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739] 5'-3' DNA helicase activity [GO:0043139]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA helicase activity [GO:0003678]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; single-stranded DNA binding [GO:0003697] 0.96752 -3.7004 KIKDDTGPVAK 8.83023 9.77213 9.7625 0 9.7698 0 9.42534 10.7791 10.7703 0 10.481 0 11.1993 10.9931 11.1525 9.95935 10.1192 10.0031 10.0178 0 9.83281 9.2644 0 0 10.2064 0 0 Q96RR4 KKCC2_HUMAN Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta) CAMKK2 CAMKKB KIAA0787 Homo sapiens (Human) activation of protein kinase activity [GO:0032147]; calcium-mediated signaling [GO:0019722]; CAMKK-AMPK signaling cascade [GO:0061762]; cellular response to reactive oxygen species [GO:0034614]; MAPK cascade [GO:0000165]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein phosphorylation [GO:0001934]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of protein kinase activity [GO:0045859] cytosol [GO:0005829]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654] ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713] 0.8262 0.21354 MSSCVSSQPSSNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.75017 0 8.64472 Q96RS0 TGS1_HUMAN Trimethylguanosine synthase (EC 2.1.1.-) (CLL-associated antigen KW-2) (Cap-specific guanine-N2 methyltransferase) (Hepatocellular carcinoma-associated antigen 137) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIMT) (PIPMT) TGS1 HCA137 NCOA6IP PIMT Homo sapiens (Human) 7-methylguanosine cap hypermethylation [GO:0036261]; 7-methylguanosine RNA capping [GO:0009452]; ribonucleoprotein complex biogenesis [GO:0022613]; spliceosomal snRNP assembly [GO:0000387] Cajal body [GO:0015030]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; small nuclear ribonucleoprotein complex [GO:0030532] RNA methyltransferase activity [GO:0008173]; RNA trimethylguanosine synthase activity [GO:0071164] 0.95456 -1.5123 EYEEDDILASDDPSSIEQYENTR 0 0 0 0 0 0 0 9.52761 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.43169 0 0 0 0 Q96RS6 NUDC1_HUMAN NudC domain-containing protein 1 (Chronic myelogenous leukemia tumor antigen 66) (Tumor antigen CML66) NUDCD1 CML66 Homo sapiens (Human) immune system process [GO:0002376] cytosol [GO:0005829]; nucleoplasm [GO:0005654] 0.96716 -3.782 LFVLTTKNLFLIK 0 0 0 0 0 0 0 0 0 9.45853 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96RT1 ERBIN_HUMAN Erbin (Densin-180-like protein) (Erbb2-interacting protein) (Protein LAP2) ERBIN ERBB2IP KIAA1225 LAP2 Homo sapiens (Human) basal protein localization [GO:0045175]; cell adhesion [GO:0007155]; cellular response to tumor necrosis factor [GO:0071356]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; integrin-mediated signaling pathway [GO:0007229]; intermediate filament cytoskeleton organization [GO:0045104]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070433]; protein targeting [GO:0006605]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; signal transduction [GO:0007165] basal plasma membrane [GO:0009925]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; glutamatergic synapse [GO:0098978]; hemidesmosome [GO:0030056]; nuclear membrane [GO:0031965]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794] ErbB-2 class receptor binding [GO:0005176]; signaling receptor binding [GO:0005102]; structural constituent of cytoskeleton [GO:0005200] 0.9555 -1.5977 LITNDTFQPEIMERSK 0 0 0 0 0 0 0 9.72433 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8521 0 0 Q96RT7 GCP6_HUMAN Gamma-tubulin complex component 6 (GCP-6) TUBGCP6 GCP6 KIAA1669 Homo sapiens (Human) cytoplasmic microtubule organization [GO:0031122]; meiotic cell cycle [GO:0051321]; microtubule nucleation [GO:0007020]; mitotic cell cycle [GO:0000278]; spindle assembly [GO:0051225] centrosome [GO:0005813]; cytosol [GO:0005829]; equatorial microtubule organizing center [GO:0000923]; gamma-tubulin complex [GO:0000930]; gamma-tubulin ring complex [GO:0000931]; membrane [GO:0016020]; microtubule [GO:0005874]; spindle pole [GO:0000922] gamma-tubulin binding [GO:0043015]; microtubule binding [GO:0008017] 0.96566 -2.7141 AAVDYFFVELHLEAHYEALR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.531 0 0 0 0 10.2148 10.8141 0 0 0 Q96RT8 GCP5_HUMAN Gamma-tubulin complex component 5 (GCP-5) TUBGCP5 GCP5 KIAA1899 Homo sapiens (Human) cytoplasmic microtubule organization [GO:0031122]; meiotic cell cycle [GO:0051321]; microtubule nucleation [GO:0007020]; mitotic cell cycle [GO:0000278]; spindle assembly [GO:0051225] centrosome [GO:0005813]; cytosol [GO:0005829]; equatorial microtubule organizing center [GO:0000923]; gamma-tubulin complex [GO:0000930]; gamma-tubulin ring complex [GO:0000931]; microtubule [GO:0005874]; spindle pole [GO:0000922] gamma-tubulin binding [GO:0043015]; microtubule binding [GO:0008017] 0.9695 -3.1542 DLDQLIKIHYR 0 0 0 10.7148 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.68361 0 0 Q96RU3 FNBP1_HUMAN Formin-binding protein 1 (Formin-binding protein 17) (hFBP17) FNBP1 FBP17 KIAA0554 Homo sapiens (Human) endocytosis [GO:0006897]; signal transduction [GO:0007165] cell cortex [GO:0005938]; clathrin-coated pit [GO:0005905]; cytoplasmic vesicle [GO:0031410]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; plasma membrane [GO:0005886] identical protein binding [GO:0042802]; lipid binding [GO:0008289] 0.88427 -0.14389 TEIELSYAKQLRNLSK 0 0 0 0 0 0 9.13168 0 9.89592 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96RU7 TRIB3_HUMAN Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase) (SINK) (p65-interacting inhibitor of NF-kappa-B) TRIB3 C20orf97 NIPK SKIP3 TRB3 Homo sapiens (Human) cellular response to insulin stimulus [GO:0032869]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein phosphorylation [GO:0006468]; regulation of autophagy [GO:0010506]; regulation of glucose transmembrane transport [GO:0010827]; regulation of MAP kinase activity [GO:0043405]; response to endoplasmic reticulum stress [GO:0034976] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; mitogen-activated protein kinase kinase binding [GO:0031434]; protein kinase binding [GO:0019901]; protein kinase inhibitor activity [GO:0004860]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase regulator activity [GO:0055106] 0.96386 -2.4139 FVFADRER 9.68452 0 0 0 0 0 0 0 0 0 0 0 12.674 0 0 0 0 0 0 0 0 10.7263 0 0 0 0 0 Q96RU8 TRIB1_HUMAN Tribbles homolog 1 (TRB-1) (G-protein-coupled receptor-induced gene 2 protein) (GIG-2) (SKIP1) TRIB1 C8FW GIG2 TRB1 Homo sapiens (Human) JNK cascade [GO:0007254]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of neutrophil differentiation [GO:0045659]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of eosinophil differentiation [GO:0045645]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of MAP kinase activity [GO:0043405]; response to lipopolysaccharide [GO:0032496] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] mitogen-activated protein kinase kinase binding [GO:0031434]; protein kinase inhibitor activity [GO:0004860]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase regulator activity [GO:0055106] 0.96048 -1.804 DFGDMHSYVR 0 0 0 0 0 0 0 10.1556 0 0 9.45629 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0584 0 0 Q96RV3 PCX1_HUMAN Pecanex-like protein 1 (Pecanex homolog protein 1) PCNX1 KIAA0805 KIAA0995 PCNX PCNXL1 Homo sapiens (Human) membrane [GO:0016020] 0.87643 -0.0063279 ARVLSLDSGTVACLNDSNR 10.1489 0 0 0 0 0 10.5248 0 10.2743 0 0 0 0 0 0 0 0 11.895 0 0 0 0 0 0 0 0 8.79938 Q96RW7 HMCN1_HUMAN Hemicentin-1 (Fibulin-6) (FIBL-6) HMCN1 FIBL6 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] adherens junction [GO:0005912]; basement membrane [GO:0005604]; cell cortex [GO:0005938]; cleavage furrow [GO:0032154]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; muscle tendon junction [GO:0005927] calcium ion binding [GO:0005509]; extracellular matrix structural constituent [GO:0005201] 0.9261 -1.2131 AINIAGTSQK 0 14.9569 0 0 0 11.2367 0 11.3882 0 10.353 0 9.76253 0 11.4724 0 0 10.1204 11.0709 0 0 0 0 0 0 0 0 0 Q96RY5 CRML_HUMAN Protein cramped-like (Cramped chromatin regulator homolog 1) (Hematological and neurological expressed 1-like protein) CRAMP1 C16orf34 CRAMP1L HN1L KIAA1426 Homo sapiens (Human) pattern specification process [GO:0007389] nucleus [GO:0005634] chromatin binding [GO:0003682]; DNA binding [GO:0003677] 0.91822 -0.88116 KSSQELYGLICYGELR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.86963 0 0 0 0 0 0 0 0 9.6669 0 0 11.7647 0 Q96RY7 IF140_HUMAN Intraflagellar transport protein 140 homolog (WD and tetratricopeptide repeats protein 2) IFT140 KIAA0590 WDTC2 Homo sapiens (Human) cilium assembly [GO:0060271]; determination of left/right symmetry [GO:0007368]; embryonic brain development [GO:1990403]; embryonic camera-type eye development [GO:0031076]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digit morphogenesis [GO:0042733]; heart development [GO:0007507]; intraciliary retrograde transport [GO:0035721]; neural tube patterning [GO:0021532]; non-motile cilium assembly [GO:1905515]; photoreceptor cell outer segment organization [GO:0035845]; protein localization to cilium [GO:0061512]; regulation of cilium assembly [GO:1902017]; regulation of smoothened signaling pathway [GO:0008589] axoneme [GO:0005930]; centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary tip [GO:0097542]; cilium [GO:0005929]; cone photoreceptor outer segment [GO:0120199]; intraciliary transport particle A [GO:0030991]; photoreceptor connecting cilium [GO:0032391] 0.95562 -1.6397 ALLKSGDTEK 0 9.53068 0 0 0 9.34074 0 0 0 10.2879 0 0 11.0163 0 0 0 0 0 0 0 0 0 0 0 0 9.2096 0 Q96S16 JMJD8_HUMAN JmjC domain-containing protein 8 (Jumonji domain-containing protein 8) JMJD8 C16orf20 PP14397 Homo sapiens (Human) positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of sprouting angiogenesis [GO:1903672]; regulation of glycolytic process [GO:0006110]; regulation of pyruvate kinase activity [GO:1903302] cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; nucleus [GO:0005634] 0.95492 -1.52 DRLLASFGDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.0972 0 0 0 0 0 0 0 0 0 0 Q96S19 MTL26_HUMAN Methyltransferase-like 26 METTL26 JFP2 C16orf13 Homo sapiens (Human) 0.87145 0.06449 VLEVASGSGQHAAHFAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.87731 Q96S38 KS6C1_HUMAN Ribosomal protein S6 kinase delta-1 (S6K-delta-1) (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein) RPS6KC1 RPK118 Homo sapiens (Human) protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] early endosome [GO:0005769]; endosome [GO:0005768]; lysosome [GO:0005764]; membrane [GO:0016020] ATP binding [GO:0005524]; phosphatidylinositol binding [GO:0035091]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.88434 -0.25236 AGELIKLALKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.63007 9.4212 0 0 0 0 0 0 0 10.4648 0 0 Q96S44 PRPK_HUMAN EKC/KEOPS complex subunit TP53RK (EC 3.6.-.-) (Atypical serine/threonine protein kinase TP53RK) (Nori-2) (TP53-regulating kinase) (EC 2.7.11.1) (p53-related protein kinase) TP53RK C20orf64 PRPK Homo sapiens (Human) protein phosphorylation [GO:0006468]; regulation of signal transduction by p53 class mediator [GO:1901796]; tRNA processing [GO:0008033]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525] cytoplasm [GO:0005737]; cytosol [GO:0005829]; EKC/KEOPS complex [GO:0000408]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; hydrolase activity [GO:0016787]; p53 binding [GO:0002039]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.61418 0.42466 GVDLYVLEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2873 0 0 0 9.19537 0 0 0 0 Q96S53 TESK2_HUMAN Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2) TESK2 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; focal adhesion assembly [GO:0048041]; protein phosphorylation [GO:0006468]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein tyrosine kinase activity [GO:0004713] 0.96001 -1.9275 ANMLKEVQLMNRLSHPNILR 0 0 0 0 0 0 0 0 0 0 0 0 8.67751 0 0 9.74987 0 0 9.55159 0 0 0 0 0 0 0 0 Q96S55 WRIP1_HUMAN ATPase WRNIP1 (EC 3.6.1.-) (Werner helicase-interacting protein 1) WRNIP1 WHIP Homo sapiens (Human) DNA synthesis involved in DNA repair [GO:0000731]; DNA-templated DNA replication [GO:0006261]; innate immune response [GO:0045087]; regulation of DNA-templated DNA replication initiation [GO:0030174] membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA binding [GO:0003677]; enzyme activator activity [GO:0008047]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA helicase activity [GO:0017116] 0.96771 -2.9536 AGLNGLQLAVLAR 0 10.0341 0 0 9.65431 0 0 10.3756 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.7057 0 0 Q96S65 CSRN1_HUMAN Cysteine/serine-rich nuclear protein 1 (CSRNP-1) (Axin-1 up-regulated gene 1 protein) (Protein URAX1) (TGF-beta-induced apoptosis protein 3) (TAIP-3) CSRNP1 AXUD1 TAIP3 Homo sapiens (Human) apoptotic process [GO:0006915]; face morphogenesis [GO:0060325]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; regulation of transcription by RNA polymerase II [GO:0006357]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific DNA binding [GO:0043565]" 0.93213 -1.274 ELQALRQSREDCGCHCDR 0 0 0 0 0 0 0 0 0 12.9306 0 10.6769 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96S66 CLCC1_HUMAN Chloride channel CLIC-like protein 1 (Mid-1-related chloride channel protein 1) CLCC1 KIAA0761 MCLC Homo sapiens (Human) chloride channel complex [GO:0034707]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondria-associated endoplasmic reticulum membrane [GO:0044233]; nuclear membrane [GO:0031965] chloride channel activity [GO:0005254] 0.88454 -0.19654 KMDWTGSIWEWFRSSWTYK 0 0 0 0 0 0 0 0 9.41667 0 0 0 0 0 0 9.42507 0 9.21772 0 0 0 0 0 0 0 9.47519 0 Q96S86 HPLN3_HUMAN Hyaluronan and proteoglycan link protein 3 HAPLN3 EXLD1 UNQ238/PRO271 Homo sapiens (Human) cell adhesion [GO:0007155]; glial cell differentiation [GO:0010001]; positive regulation of neuroblast proliferation [GO:0002052]; response to estrogen [GO:0043627] extracellular space [GO:0005615]; perineuronal net [GO:0072534]; synapse [GO:0045202] hyaluronic acid binding [GO:0005540] 0.89866 -0.57035 VGQLFAAWK 0 0 0 0 0 0 0 0 0 0 0 0 9.46862 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96S94 CCNL2_HUMAN Cyclin-L2 (Paneth cell-enhanced expression protein) CCNL2 SB138 Homo sapiens (Human) regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of centrosome cycle [GO:0046605]; regulation of RNA splicing [GO:0043484]; regulation of transcription by RNA polymerase II [GO:0006357] cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; intracellular membrane-bounded organelle [GO:0043231]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538] 0.93985 -1.3177 TGRRYER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.7212 0 0 0 Q96SB3 NEB2_HUMAN Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin) PPP1R9B PPP1R6 Homo sapiens (Human) actin filament depolymerization [GO:0030042]; actin filament organization [GO:0007015]; aging [GO:0007568]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to morphine [GO:0071315]; cellular response to peptide [GO:1901653]; cellular response to xenobiotic stimulus [GO:0071466]; cerebral cortex development [GO:0021987]; dendrite development [GO:0016358]; developmental process involved in reproduction [GO:0003006]; filopodium assembly [GO:0046847]; hippocampus development [GO:0021766]; learning [GO:0007612]; male mating behavior [GO:0060179]; negative regulation of cell growth [GO:0030308]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; neuron projection development [GO:0031175]; positive regulation of protein localization to actin cortical patch [GO:1904372]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to actin cytoskeleton [GO:1903119]; protein localization to cell periphery [GO:1990778]; regulation of cell cycle [GO:0051726]; regulation of cell growth by extracellular stimulus [GO:0001560]; regulation of cell population proliferation [GO:0042127]; regulation of exit from mitosis [GO:0007096]; regulation of opioid receptor signaling pathway [GO:2000474]; regulation of protein phosphorylation [GO:0001932]; reproductive system development [GO:0061458]; response to amphetamine [GO:0001975]; response to clozapine [GO:0097338]; response to immobilization stress [GO:0035902]; response to kainic acid [GO:1904373]; response to L-phenylalanine derivative [GO:1904386]; response to nicotine [GO:0035094]; response to prostaglandin E [GO:0034695]; response to steroid hormone [GO:0048545]; RNA splicing [GO:0008380] actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoplasmic side of dendritic spine plasma membrane [GO:1990780]; dendrite [GO:0030425]; dendritic spine head [GO:0044327]; dendritic spine neck [GO:0044326]; filopodium [GO:0030175]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein phosphatase type 1 complex [GO:0000164]; ruffle membrane [GO:0032587] actin filament binding [GO:0051015]; D2 dopamine receptor binding [GO:0031749]; kinase binding [GO:0019900]; protein kinase activity [GO:0004672]; protein phosphatase 1 binding [GO:0008157]; protein phosphatase inhibitor activity [GO:0004864]; transmembrane transporter binding [GO:0044325] 0.9239 -1.0293 LGTSVSERVSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2144 0 0 0 0 0 0 0 0 0 0 0 Q96SB4 SRPK1_HUMAN SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1) SRPK1 Homo sapiens (Human) "chromosome segregation [GO:0007059]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of viral genome replication [GO:0045071]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of viral genome replication [GO:0045070]; protein phosphorylation [GO:0006468]; regulation of mRNA processing [GO:0050684]; regulation of mRNA splicing, via spliceosome [GO:0048024]; RNA splicing [GO:0008380]; sperm DNA condensation [GO:0035092]; spliceosomal complex assembly [GO:0000245]" chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; RNA binding [GO:0003723] 0.96854 -3.3483 KSETQHR 8.82133 0 0 0 0 0 9.57249 9.37263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96SB8 SMC6_HUMAN Structural maintenance of chromosomes protein 6 (SMC protein 6) (SMC-6) (hSMC6) SMC6 SMC6L1 Homo sapiens (Human) cellular senescence [GO:0090398]; DNA damage response [GO:0006974]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation by host of viral genome replication [GO:0044828]; positive regulation of chromosome segregation [GO:0051984]; protein sumoylation [GO:0016925]; regulation of telomere maintenance [GO:0032204]; telomere maintenance via recombination [GO:0000722] "chromosome, centromeric region [GO:0000775]; chromosome, telomeric region [GO:0000781]; interchromatin granule [GO:0035061]; mitotic spindle pole [GO:0097431]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; sex chromosome [GO:0000803]; site of double-strand break [GO:0035861]; Smc5-Smc6 complex [GO:0030915]" ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA secondary structure binding [GO:0000217]; single-stranded DNA binding [GO:0003697]; ubiquitin protein ligase binding [GO:0031625] 0.96272 -2.1817 EAFTADGDQVFAGR 0 0 9.44675 9.86471 0 10.1034 10.4324 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96SC8 DMTA2_HUMAN Doublesex- and mab-3-related transcription factor A2 (Doublesex- and mab-3-related transcription factor 5) DMRTA2 DMRT5 Homo sapiens (Human) cerebral cortex regionalization [GO:0021796]; dopaminergic neuron differentiation [GO:0071542]; germ cell development [GO:0007281]; neuroblast proliferation [GO:0007405]; neuron fate specification [GO:0048665]; positive regulation of neuroblast proliferation [GO:0002052]; regulation of transcription by RNA polymerase II [GO:0006357]; sex differentiation [GO:0007548]; skeletal muscle cell differentiation [GO:0035914]; stem cell fate specification [GO:0048866] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.95354 -1.4965 TPLDILTRVFPGHR 11.9413 0 0 0 0 0 12.0919 0 12.0533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96SD1 DCR1C_HUMAN Protein artemis (EC 3.1.-.-) (DNA cross-link repair 1C protein) (Protein A-SCID) (SNM1 homolog C) (hSNM1C) (SNM1-like protein) DCLRE1C ARTEMIS ASCID SCIDA SNM1C Homo sapiens (Human) adaptive immune response [GO:0002250]; B cell differentiation [GO:0030183]; double-strand break repair via nonhomologous end joining [GO:0006303]; interstrand cross-link repair [GO:0036297]; response to ionizing radiation [GO:0010212]; telomere maintenance [GO:0000723]; V(D)J recombination [GO:0033151] Golgi apparatus [GO:0005794]; nonhomologous end joining complex [GO:0070419]; nucleoplasm [GO:0005654] 5'-3' DNA exonuclease activity [GO:0035312]; 5'-3' exonuclease activity [GO:0008409]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; single-stranded DNA endodeoxyribonuclease activity [GO:0000014] 0.95896 -1.736 ADGDVPQWEVFFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.99036 0 0 0 Q96SE7 ZN347_HUMAN Zinc finger protein 347 (Zinc finger protein 1111) ZNF347 ZNF1111 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.86894 0.067337 NTHGLEYQCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.88408 0 0 0 0 0 0 0 0 0 0 0 Q96SI1 KCD15_HUMAN BTB/POZ domain-containing protein KCTD15 (Potassium channel tetramerization domain-containing protein 15) KCTD15 Homo sapiens (Human) protein homooligomerization [GO:0051260] nucleus [GO:0005634] identical protein binding [GO:0042802] 0.95435 -1.5264 VTPDLGERIALSGEK 0 0 0 0 0 0 0 0 0 0 9.56396 0 0 9.27559 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96SK3 ZN607_HUMAN Zinc finger protein 607 ZNF607 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.91031 -0.74725 IYSGEKHYECK 0 8.90992 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96SL4 GPX7_HUMAN Glutathione peroxidase 7 (GPx-7) (GSHPx-7) (EC 1.11.1.9) (CL683) GPX7 GPX6 UNQ469/PRO828 Homo sapiens (Human) cellular response to oxidative stress [GO:0034599] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576] catalase activity [GO:0004096]; glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601] 0.91454 -0.8326 EIESFARR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0204 0 0 0 Q96SM3 CPXM1_HUMAN Probable carboxypeptidase X1 (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1) CPXM1 CPX1 CPXM UNQ3015/PRO9782 Homo sapiens (Human) peptide metabolic process [GO:0006518]; protein processing [GO:0016485] extracellular space [GO:0005615] metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270] 0.94729 -1.3479 AVIKWMKR 0 0 0 0 11.3485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96SN8 CK5P2_HUMAN CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215) CDK5RAP2 CEP215 KIAA1633 Homo sapiens (Human) brain development [GO:0007420]; centriole replication [GO:0007099]; centrosome cycle [GO:0007098]; chromosome segregation [GO:0007059]; establishment of mitotic spindle orientation [GO:0000132]; microtubule bundle formation [GO:0001578]; microtubule cytoskeleton organization [GO:0000226]; microtubule organizing center organization [GO:0031023]; negative regulation of centriole replication [GO:0046600]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of neuron differentiation [GO:0045665]; neurogenesis [GO:0022008]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of microtubule polymerization [GO:0031116]; regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090266]; regulation of neuron differentiation [GO:0045664] cell junction [GO:0030054]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; microtubule [GO:0005874]; microtubule plus-end [GO:0035371]; mitotic spindle pole [GO:0097431]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]; spindle pole [GO:0000922] calmodulin binding [GO:0005516]; gamma-tubulin binding [GO:0043015]; microtubule binding [GO:0008017]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; transcription cis-regulatory region binding [GO:0000976]; tubulin binding [GO:0015631] 0.96894 -10.729 CSSQQPPGSK 10.1925 10.7893 11.049 9.72216 10.8897 9.69827 11.7847 12.3153 11.6424 0 0 11.3369 0 0 0 0 10.2336 0 0 0 0 10.9255 9.31209 0 0 10.4219 10.5073 Q96SQ5 ZN587_HUMAN Zinc finger protein 587 ZNF587 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.9494 -1.3805 GNLVHHQRGHTGERPYECK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.05544 0 0 0 0 0 0 9.23024 9.01288 0 0 10.2138 11.1429 0 Q96SQ9 CP2S1_HUMAN Cytochrome P450 2S1 (EC 1.14.14.-) (CYPIIS1) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152) (Thromboxane-A synthase) (EC 5.3.99.5) CYP2S1 UNQ891/PRO1906 Homo sapiens (Human) epoxygenase P450 pathway [GO:0019373]; icosanoid metabolic process [GO:0006690]; prostaglandin metabolic process [GO:0006693]; retinoic acid metabolic process [GO:0042573]; xenobiotic metabolic process [GO:0006805] cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231] "12-hydroxyheptadecatrienoic acid synthase activity [GO:0036134]; arachidonic acid epoxygenase activity [GO:0008392]; heme binding [GO:0020037]; hydro-lyase activity [GO:0016836]; hydroperoxy icosatetraenoate dehydratase activity [GO:0106256]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; retinoic acid 4-hydroxylase activity [GO:0008401]; thromboxane-A synthase activity [GO:0004796]" 0.86902 0.067032 HPEEFNPDRFLDADGR 0 9.3376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96SR6 ZN382_HUMAN Zinc finger protein 382 (KRAB/zinc finger suppressor protein 1) (KS1) (Multiple zinc finger and krueppel-associated box protein KS1) ZNF382 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96192 -2.4543 GERTFEYNK 9.76764 0 0 0 9.14389 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5989 0 0 0 0 Q96ST2 IWS1_HUMAN Protein IWS1 homolog (IWS1-like protein) IWS1 IWS1L Homo sapiens (Human) chromatin remodeling [GO:0006338]; mRNA processing [GO:0006397]; poly(A)+ mRNA export from nucleus [GO:0016973]; regulation of mRNA export from nucleus [GO:0010793]; regulation of mRNA processing [GO:0050684]; RNA splicing [GO:0008380]; transcription elongation-coupled chromatin remodeling [GO:0140673] nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.96359 -2.1433 EEREQRDLEQMPQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0744 0 10.2779 0 0 0 Q96ST3 SIN3A_HUMAN Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a) SIN3A Homo sapiens (Human) activation of innate immune response [GO:0002218]; aging [GO:0007568]; cellular response to dopamine [GO:1903351]; cellular response to glucose stimulus [GO:0071333]; cerebral cortex neuron differentiation [GO:0021895]; DNA replication [GO:0006260]; hematopoietic progenitor cell differentiation [GO:0002244]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell migration [GO:0030336]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of heterochromatin formation [GO:0031453]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization [GO:0008104]; regulation of axon extension [GO:0030516]; regulation of hormone levels [GO:0010817]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to methylglyoxal [GO:0051595]; rhythmic process [GO:0048511] chromatin [GO:0000785]; histone deacetylase complex [GO:0000118]; kinetochore [GO:0000776]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Sin3 complex [GO:0016580]; transcription repressor complex [GO:0017053] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription regulator inhibitor activity [GO:0140416] 0.92379 -1.0188 ALQRIYADK 0 0 0 0 0 0 0 0 0 0 0 12.7632 0 0 0 0 0 0 0 0 10.4635 0 0 0 0 0 0 Q96ST8 CEP89_HUMAN Centrosomal protein of 89 kDa (Cep89) (Centrosomal protein 123) (Cep123) (Coiled-coil domain-containing protein 123) CEP89 CCDC123 Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; cilium assembly [GO:0060271]; mitochondrion organization [GO:0007005]; non-motile cilium assembly [GO:1905515] centriole [GO:0005814]; centrosome [GO:0005813]; ciliary transition fiber [GO:0097539]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; motile cilium [GO:0031514]; non-motile cilium [GO:0097730]; spindle pole [GO:0000922]; synapse [GO:0045202] 0.96995 -4.3743 AAVPRTPPPR 0 0 0 0 0 0 0 0 0 0 0 10.0538 0 0 0 0 0 0 10.971 0 9.67005 0 0 0 0 0 0 Q96SU4 OSBL9_HUMAN Oxysterol-binding protein-related protein 9 (ORP-9) (OSBP-related protein 9) OSBPL9 ORP9 OSBP4 Homo sapiens (Human) bile acid biosynthetic process [GO:0006699] cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; membrane [GO:0016020] sterol binding [GO:0032934]; sterol transporter activity [GO:0015248] 0.96218 -2.4933 DIDAATEAK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9496 0 0 0 0 0 0 0 9.46655 0 0 0 0 0 Q96SW2 CRBN_HUMAN Protein cereblon CRBN AD-006 Homo sapiens (Human) locomotory exploration behavior [GO:0035641]; negative regulation of large conductance calcium-activated potassium channel activity [GO:1902607]; negative regulation of protein-containing complex assembly [GO:0031333]; positive regulation of protein-containing complex assembly [GO:0031334]; positive regulation of Wnt signaling pathway [GO:0030177]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567] Cul4A-RING E3 ubiquitin ligase complex [GO:0031464]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] metal ion binding [GO:0046872]; transmembrane transporter binding [GO:0044325] 0.88324 -0.069018 KFHCANLTSWPR 0 9.71225 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96SZ4 ZSC10_HUMAN Zinc finger and SCAN domain-containing protein 10 (Zinc finger protein 206) ZSCAN10 ZNF206 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892] nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565] 0.89889 -0.68189 FVRRASLAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5706 0 0 0 0 0 0 0 0 12.3886 0 0 Q96SZ6 CK5P1_HUMAN Mitochondrial tRNA methylthiotransferase CDK5RAP1 (EC 2.8.4.3) (CDK5 activator-binding protein C42) (CDK5 regulatory subunit-associated protein 1) (mt-tRNA-2-methylthio-N6-dimethylallyladenosine synthase) (mt-tRNA-N6-(dimethylallyl)adenosine(37) methylthiotransferase) CDK5RAP1 C20orf34 CGI-05 HSPC167 Homo sapiens (Human) brain development [GO:0007420]; mitochondrial tRNA modification [GO:0070900]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; positive regulation of mitochondrial translation [GO:0070131]; positive regulation of translational fidelity [GO:0045903]; regulation of neuron differentiation [GO:0045664] cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] "4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]; N6-isopentenyladenosine methylthiotransferase activity [GO:0035597]; protein kinase binding [GO:0019901]" 0.96392 -2.2185 HPLQCVLQVQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.54824 0 0 0 0 Q96T17 MA7D2_HUMAN MAP7 domain-containing protein 2 MAP7D2 Homo sapiens (Human) microtubule cytoskeleton organization [GO:0000226] microtubule cytoskeleton [GO:0015630] 0.63118 0.4083 CLAAREQQILEKQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.54496 0 11.2227 0 0 Q96T21 SEBP2_HUMAN Selenocysteine insertion sequence-binding protein 2 (SECIS-binding protein 2) SECISBP2 SBP2 Homo sapiens (Human) "forebrain neuron development [GO:0021884]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; selenocysteine incorporation [GO:0001514]; striatum development [GO:0021756]" mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ribonucleoprotein complex [GO:1990904] DNA binding [GO:0003677]; mRNA 3'-UTR binding [GO:0003730]; ribonucleoprotein complex binding [GO:0043021]; RNA binding [GO:0003723]; selenocysteine insertion sequence binding [GO:0035368] 0.91538 -0.77031 FQSKQQPQDNFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5427 0 9.51094 0 0 0 0 0 0 0 0 Q96T23 RSF1_HUMAN Remodeling and spacing factor 1 (Rsf-1) (HBV pX-associated protein 8) (Hepatitis B virus X-associated protein) (p325 subunit of RSF chromatin-remodeling complex) RSF1 HBXAP XAP8 Homo sapiens (Human) chromatin remodeling [GO:0006338]; DNA-templated transcription initiation [GO:0006352]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-templated transcription [GO:0045892]; nucleosome assembly [GO:0006334]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of viral transcription [GO:0050434]; regulation of DNA-templated transcription [GO:0006355] nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RSF complex [GO:0031213] histone binding [GO:0042393]; histone octamer slider activity [GO:0140751]; metal ion binding [GO:0046872] 0.96399 -2.2588 AQIDPVLLK 13.5342 13.726 0 0 0 0 13.4253 13.5492 13.5303 13.2923 12.9438 0 12.0161 11.9056 11.9062 0 0 0 0 0 0 0 0 0 0 0 0 Q96T25 ZIC5_HUMAN Zinc finger protein ZIC 5 (Zinc finger protein of the cerebellum 5) ZIC5 Homo sapiens (Human) cell differentiation [GO:0030154]; central nervous system development [GO:0007417]; regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96798 -2.8804 HMKIHCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.2555 0 0 0 0 0 0 9.73897 0 Q96T37 RBM15_HUMAN RNA-binding protein 15 (One-twenty two protein 1) (RNA-binding motif protein 15) RBM15 OTT OTT1 Homo sapiens (Human) "branching involved in blood vessel morphogenesis [GO:0001569]; dosage compensation by inactivation of X chromosome [GO:0009048]; negative regulation of myeloid cell differentiation [GO:0045638]; placenta blood vessel development [GO:0060674]; positive regulation of transcription of Notch receptor target [GO:0007221]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of megakaryocyte differentiation [GO:0045652]; RNA methylation [GO:0001510]; spleen development [GO:0048536]; thrombopoietin-mediated signaling pathway [GO:0038163]; ventricular septum morphogenesis [GO:0060412]" nuclear membrane [GO:0031965]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA N6-methyladenosine methyltransferase complex [GO:0036396] mRNA binding [GO:0003729]; RNA binding [GO:0003723] 0.96929 -3.4233 KNSASAERDR 10.7224 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.14776 0 10.2055 0 0 0 0 10.746 0 0 0 0 Q96T51 RUFY1_HUMAN RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (La-binding protein 1) (Rab4-interacting protein) (Zinc finger FYVE domain-containing protein 12) RUFY1 RABIP4 ZFYVE12 Homo sapiens (Human) endocytosis [GO:0006897]; protein transport [GO:0015031]; regulation of endocytosis [GO:0030100]; small GTPase mediated signal transduction [GO:0007264] cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; intracellular membrane-bounded organelle [GO:0043231]; nuclear speck [GO:0016607] identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124] 0.38792 0.71389 DVQDLDGGK 0 0 0 0 0 0 8.99577 0 0 8.94375 0 9.27833 0 0 0 0 11.409 10.5494 0 0 0 0 0 0 0 10.685 0 Q96T52 IMP2L_HUMAN Mitochondrial inner membrane protease subunit 2 (EC 3.4.21.-) (IMP2-like protein) IMMP2L Homo sapiens (Human) blood circulation [GO:0008015]; brain development [GO:0007420]; cerebellum vasculature development [GO:0061300]; DNA damage response [GO:0006974]; mitochondrial respiratory chain complex assembly [GO:0033108]; ovarian follicle development [GO:0001541]; ovulation [GO:0030728]; protein processing involved in protein targeting to mitochondrion [GO:0006627]; respiratory electron transport chain [GO:0022904]; signal peptide processing [GO:0006465]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801] mitochondrial inner membrane [GO:0005743]; mitochondrial inner membrane peptidase complex [GO:0042720] endopeptidase activity [GO:0004175]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252] 0.96884 -3.0107 NRYVKVPR 0 0 0 0 0 0 0 0 0 0 0 0 11.2298 0 0 0 9.10575 0 0 0 0 0 0 0 0 0 0 Q96T53 MBOA4_HUMAN Ghrelin O-acyltransferase (EC 2.3.1.-) (Membrane-bound O-acyltransferase domain-containing protein 4) (O-acyltransferase domain-containing protein 4) MBOAT4 GOAT OACT4 FKSG89 Homo sapiens (Human) lipid modification [GO:0030258]; peptide hormone processing [GO:0016486]; peptidyl-serine octanoylation [GO:0018191]; protein decanoylation [GO:0051366] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] "acyltransferase activity, transferring groups other than amino-acyl groups [GO:0016747]; O-acyltransferase activity [GO:0008374]; serine O-acyltransferase activity [GO:0016412]" 0.6673 0.39409 AASGGFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0065 0 0 0 0 0 9.62994 8.62783 0 0 0 0 Q96T58 MINT_HUMAN Msx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog) SPEN KIAA0929 MINT SHARP Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of neurogenesis [GO:0050769]; regulation of transcription by RNA polymerase II [GO:0006357] extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription repressor complex [GO:0017053] DNA binding [GO:0003677]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription corepressor activity [GO:0003714] 0.96481 -2.3802 DPRERTLQHGLYYASR 0 0 0 9.84438 0 10.5096 0 14.5072 8.4543 0 0 0 0 0 0 0 8.9002 0 0 0 0 0 9.62337 0 8.82177 0 0 Q96T60 PNKP_HUMAN Bifunctional polynucleotide phosphatase/kinase (DNA 5'-kinase/3'-phosphatase) (Polynucleotide kinase-3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)] PNKP Homo sapiens (Human) "base-excision repair, gap-filling [GO:0006287]; DNA ligation involved in DNA repair [GO:0051103]; DNA repair [GO:0006281]; DNA-templated DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide-excision repair [GO:0006289]; phosphorylation [GO:0016310]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]" membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861] ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; double-stranded DNA binding [GO:0003690]; endonuclease activity [GO:0004519]; polydeoxyribonucleotide 5'-hydroxyl-kinase activity [GO:0046404]; polynucleotide 3'-phosphatase activity [GO:0046403]; purine nucleotide binding [GO:0017076] 0.9673 -2.86 ARYVQCAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3664 0 0 Q96T66 NMNA3_HUMAN Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 (NMN/NaMN adenylyltransferase 3) (Nicotinamide-nucleotide adenylyltransferase 3) (NMN adenylyltransferase 3) (Nicotinate-nucleotide adenylyltransferase 3) (NaMN adenylyltransferase 3) (EC 2.7.7.18) (Pyridine nucleotide adenylyltransferase 3) (PNAT-3) (EC 2.7.7.1) NMNAT3 FKSG76 Homo sapiens (Human) NAD biosynthetic process [GO:0009435]; nucleotide biosynthetic process [GO:0009165] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515] 0.9563 -1.5501 VLRHHHSK 0 0 0 9.71339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96T68 SETB2_HUMAN Histone-lysine N-methyltransferase SETDB2 (EC 2.1.1.366) (Chronic lymphocytic leukemia deletion region gene 8 protein) (Lysine N-methyltransferase 1F) (SET domain bifurcated 2) SETDB2 C13orf4 CLLD8 KMT1F Homo sapiens (Human) cell division [GO:0051301]; chromosome segregation [GO:0007059]; heart looping [GO:0001947]; heterochromatin organization [GO:0070828]; histone H3-K9 methylation [GO:0051567]; left/right axis specification [GO:0070986]; mitotic cell cycle [GO:0000278]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309] chromosome [GO:0005694]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; histone H3K9 methyltransferase activity [GO:0046974]; histone H3K9 monomethyltransferase activity [GO:0140948]; zinc ion binding [GO:0008270] 0.96958 -4.8802 ITTGYKYK 0 0 9.13489 0 0 0 13.5723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96T76 MMS19_HUMAN MMS19 nucleotide excision repair protein homolog (hMMS19) (MET18 homolog) (MMS19-like protein) MMS19 MMS19L Homo sapiens (Human) chromosome segregation [GO:0007059]; DNA damage response [GO:0006974]; DNA metabolic process [GO:0006259]; DNA repair [GO:0006281]; DNA-templated transcription [GO:0006351]; iron-sulfur cluster assembly [GO:0016226]; nucleotide-excision repair [GO:0006289]; phosphorelay signal transduction system [GO:0000160]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein maturation by iron-sulfur cluster transfer [GO:0097428]; response to hormone [GO:0009725] CIA complex [GO:0097361]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; MMXD complex [GO:0071817]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819]; transcription factor TFIIH holo complex [GO:0005675] enzyme binding [GO:0019899]; nuclear estrogen receptor binding [GO:0030331]; protein-macromolecule adaptor activity [GO:0030674]; signaling receptor complex adaptor activity [GO:0030159]; transcription coactivator activity [GO:0003713] 0.75973 0.29533 EVFQTASER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.33517 0 9.97427 0 0 9.55507 0 0 Q96T88 UHRF1_HUMAN E3 ubiquitin-protein ligase UHRF1 (EC 2.3.2.27) (Inverted CCAAT box-binding protein of 90 kDa) (Nuclear protein 95) (Nuclear zinc finger protein Np95) (HuNp95) (hNp95) (RING finger protein 106) (RING-type E3 ubiquitin transferase UHRF1) (Transcription factor ICBP90) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (hUHRF1) (Ubiquitin-like-containing PHD and RING finger domains protein 1) UHRF1 ICBP90 NP95 RNF106 Homo sapiens (Human) cell cycle [GO:0007049]; DNA repair [GO:0006281]; heterochromatin formation [GO:0031507]; histone monoubiquitination [GO:0010390]; negative regulation of gene expression via CpG island methylation [GO:0044027]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity [GO:2000373]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autoubiquitination [GO:0051865]; regulation of epithelial cell proliferation [GO:0050678]; ubiquitin-dependent protein catabolic process [GO:0006511] chromatin [GO:0000785]; euchromatin [GO:0000791]; heterochromatin [GO:0000792]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; replication fork [GO:0005657] cis-regulatory region sequence-specific DNA binding [GO:0000987]; hemi-methylated DNA-binding [GO:0044729]; histone binding [GO:0042393]; identical protein binding [GO:0042802]; methyl-CpG binding [GO:0008327]; methylated histone binding [GO:0035064]; nucleic acid binding [GO:0003676]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.96298 -2.0907 DCLDRSFRAQVFSCPACR 0 0 9.96723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.16461 0 0 0 0 0 0 9.18567 Q96TA1 NIBA2_HUMAN Protein Niban 2 (Meg-3) (Melanoma invasion by ERK) (MINERVA) (Niban-like protein 1) (Protein FAM129B) NIBAN2 C9orf88 FAM129B Homo sapiens (Human) axon guidance [GO:0007411]; cell differentiation [GO:0030154]; gonadotropin secretion [GO:0032274]; negative regulation of angiogenesis [GO:0016525]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA biosynthetic process [GO:2000279]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of embryonic development [GO:0040019]; positive regulation of gene expression via CpG island demethylation [GO:0044029]; positive regulation of skeletal muscle fiber development [GO:0048743]; positive regulation of transcription regulatory region DNA binding [GO:2000679] adherens junction [GO:0005912]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] cadherin binding [GO:0045296]; transcription coactivator activity [GO:0003713] 0.11691 1.0939 LDGLQQR 0 0 0 0 9.04851 0 0 0 0 0 0 0 0 0 0 0 0 10.4069 0 0 0 0 0 0 0 0 10.9088 Q96TA2 YMEL1_HUMAN ATP-dependent zinc metalloprotease YME1L1 (EC 3.4.24.-) (ATP-dependent metalloprotease FtsH1) (Meg-4) (Presenilin-associated metalloprotease) (PAMP) (YME1-like protein 1) YME1L1 FTSH1 YME1L UNQ1868/PRO4304 Homo sapiens (Human) cell population proliferation [GO:0008283]; mitochondrial protein catabolic process [GO:0035694]; mitochondrial protein processing [GO:0034982]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; protein hexamerization [GO:0034214]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515] membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; nuclear body [GO:0016604] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent peptidase activity [GO:0004176]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222] 0.96791 -2.8861 GKIFEGYR 0 0 0 0 0 0 0 0 0 9.4735 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q96TC7 RMD3_HUMAN Regulator of microtubule dynamics protein 3 (RMD-3) (hRMD-3) (Cerebral protein 10) (Protein FAM82A2) (Protein FAM82C) (Protein tyrosine phosphatase-interacting protein 51) (TCPTP-interacting protein 51) RMDN3 FAM82A2 FAM82C PTPIP51 hucep-10 UNQ3122/PRO10274 Homo sapiens (Human) apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; intracellular calcium ion homeostasis [GO:0006874] cytoplasm [GO:0005737]; intercellular bridge [GO:0045171]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; mitotic spindle pole [GO:0097431]; nucleus [GO:0005634]; organelle membrane contact site [GO:0044232]; spindle microtubule [GO:0005876] microtubule binding [GO:0008017] 0.95971 -1.9631 AEELQPGFSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2403 0 11.0609 Q99062 CSF3R_HUMAN Granulocyte colony-stimulating factor receptor (G-CSF receptor) (G-CSF-R) (CD antigen CD114) CSF3R GCSFR Homo sapiens (Human) cell adhesion [GO:0007155]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; neutrophil chemotaxis [GO:0030593]; regulation of myeloid cell differentiation [GO:0045637]; signal transduction [GO:0007165] endocytic vesicle membrane [GO:0030666]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; granulocyte colony-stimulating factor binding [GO:0051916]; signaling receptor activity [GO:0038023] 0.95909 -1.7628 LDTWWRQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.68401 0 0 9.38524 0 10.1258 0 0 0 0 Q99102 MUC4_HUMAN Mucin-4 (MUC-4) (Ascites sialoglycoprotein) (ASGP) (Pancreatic adenocarcinoma mucin) (Testis mucin) (Tracheobronchial mucin) [Cleaved into: Mucin-4 alpha chain (Ascites sialoglycoprotein 1) (ASGP-1); Mucin-4 beta chain (Ascites sialoglycoprotein 2) (ASGP-2)] MUC4 Homo sapiens (Human) cell-matrix adhesion [GO:0007160]; maintenance of gastrointestinal epithelium [GO:0030277]; regulation of signaling receptor activity [GO:0010469] extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; membrane [GO:0016020]; plasma membrane [GO:0005886]; vesicle [GO:0031982] "ErbB-2 class receptor binding [GO:0005176]; extracellular matrix constituent, lubricant activity [GO:0030197]" 0.87002 0.041356 VGNSSLEVAGCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.10743 0 Q99250 SCN2A_HUMAN Sodium channel protein type 2 subunit alpha (HBSC II) (Sodium channel protein brain II subunit alpha) (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) SCN2A NAC2 SCN2A1 SCN2A2 Homo sapiens (Human) calcium ion import across plasma membrane [GO:0098703]; cellular response to hypoxia [GO:0071456]; intrinsic apoptotic signaling pathway in response to osmotic stress [GO:0008627]; memory [GO:0007613]; myelination [GO:0042552]; nervous system development [GO:0007399]; neuron apoptotic process [GO:0051402]; regulation of monoatomic ion transmembrane transport [GO:0034765]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] axon [GO:0030424]; glutamatergic synapse [GO:0098978]; intercalated disc [GO:0014704]; membrane [GO:0016020]; node of Ranvier [GO:0033268]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; sodium channel complex [GO:0034706]; T-tubule [GO:0030315]; voltage-gated calcium channel complex [GO:0005891]; voltage-gated sodium channel complex [GO:0001518] calmodulin binding [GO:0005516]; growth factor binding [GO:0019838]; high voltage-gated calcium channel activity [GO:0008331]; voltage-gated sodium channel activity [GO:0005248] 0.96965 -4.7425 ECDGTPIKEDTLIDKLNENSTPEK 0 0 0 0 0 0 0 0 9.29002 0 0 10.8054 0 9.72298 0 0 0 0 0 0 0 0 0 0 0 10.4163 0 Q99259 DCE1_HUMAN Glutamate decarboxylase 1 (EC 4.1.1.15) (67 kDa glutamic acid decarboxylase) (GAD-67) (Glutamate decarboxylase 67 kDa isoform) GAD1 GAD GAD67 Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid biosynthetic process [GO:0009449]; glutamate catabolic process [GO:0006538]; glutamate decarboxylation to succinate [GO:0006540]; locomotory exploration behavior [GO:0035641]; neurotransmitter biosynthetic process [GO:0042136]; protein-pyridoxal-5-phosphate linkage [GO:0018352]; social behavior [GO:0035176] axon terminus [GO:0043679]; cell cortex [GO:0005938]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; cytoplasm [GO:0005737]; GABA-ergic synapse [GO:0098982]; inhibitory synapse [GO:0060077]; plasma membrane [GO:0005886]; presynaptic active zone [GO:0048786]; vesicle membrane [GO:0012506] glutamate decarboxylase activity [GO:0004351]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170] 0.96877 -3.3354 GVPDSPQRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.58605 0 0 Q99417 MYCBP_HUMAN c-Myc-binding protein (Associate of Myc 1) (AMY-1) MYCBP AMY1 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] transcription coactivator activity [GO:0003713] 0.55726 0.5539 LELAEMKEK 0 9.72719 9.40971 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q99418 CYH2_HUMAN "Cytohesin-2 (ARF exchange factor) (ARF nucleotide-binding site opener) (Protein ARNO) (PH, SEC7 and coiled-coil domain-containing protein 2)" CYTH2 ARNO PSCD2 PSCD2L Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; endocytosis [GO:0006897]; regulation of ARF protein signal transduction [GO:0032012] adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; growth cone [GO:0030426]; membrane [GO:0016020]; plasma membrane [GO:0005886] "guanyl-nucleotide exchange factor activity [GO:0005085]; inositol 1,4,5 trisphosphate binding [GO:0070679]; lipid binding [GO:0008289]" 0.91177 -0.752 ISAPTQEEKDEWIK 9.7494 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q99424 ACOX2_HUMAN "Peroxisomal acyl-coenzyme A oxidase 2 (EC 1.17.99.3) (3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase) (3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase) (Trihydroxycoprostanoyl-CoA oxidase) (THCA-CoA oxidase) (THCCox)" ACOX2 Homo sapiens (Human) bile acid biosynthetic process [GO:0006699]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088]; very long-chain fatty acid metabolic process [GO:0000038] cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777] "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity [GO:0033791]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]; palmitoyl-CoA oxidase activity [GO:0016401]; protein homodimerization activity [GO:0042803]" 0.9146 -0.78873 ALSGDVALNIHRVFVRALR 0 0 0 0 0 16.1878 0 0 0 0 0 0 0 0 0 10.2853 0 0 0 0 0 0 0 0 0 0 0 Q99426 TBCB_HUMAN Tubulin-folding cofactor B (Cytoskeleton-associated protein 1) (Cytoskeleton-associated protein CKAPI) (Tubulin-specific chaperone B) TBCB CG22 CKAP1 Homo sapiens (Human) cell differentiation [GO:0030154]; cytoplasmic microtubule organization [GO:0031122]; nervous system development [GO:0007399]; post-chaperonin tubulin folding pathway [GO:0007023]; tubulin complex assembly [GO:0007021] cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; microtubule cytoskeleton [GO:0015630]; microtubule plus-end [GO:0035371]; nucleus [GO:0005634] alpha-tubulin binding [GO:0043014]; microtubule plus-end binding [GO:0051010] 0.86205 0.094928 VEKYTISQEAYDQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4185 Q99435 NELL2_HUMAN Protein kinase C-binding protein NELL2 (NEL-like protein 2) (Nel-related protein 2) NELL2 NRP2 Homo sapiens (Human) fertilization [GO:0009566]; neuron cellular homeostasis [GO:0070050] extracellular region [GO:0005576]; extracellular space [GO:0005615] calcium ion binding [GO:0005509]; heparin binding [GO:0008201] 0.95903 -1.7161 NEVRLHYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0877 0 0 0 0 0 11.3935 0 Q99436 PSB7_HUMAN Proteasome subunit beta type-7 (EC 3.4.25.1) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z) (Proteasome subunit Z) PSMB7 Z Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] "cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]" endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298] 0.8981 -0.55329 DGIVLGADTR 9.8069 0 0 0 0 0 0 0 0 0 0 0 0 0 9.7275 0 0 0 0 0 0 0 0 0 0 0 0 Q99447 PCY2_HUMAN Ethanolamine-phosphate cytidylyltransferase (EC 2.7.7.14) (CTP:phosphoethanolamine cytidylyltransferase) (Phosphorylethanolamine transferase) PCYT2 Homo sapiens (Human) phosphatidylethanolamine biosynthetic process [GO:0006646]; phospholipid biosynthetic process [GO:0008654] cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789] ethanolamine-phosphate cytidylyltransferase activity [GO:0004306] 0.87379 0.035363 AHHSSQEMSSEYR 0 0 0 0 0 0 0 0 0 11.9711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q99456 K1C12_HUMAN "Keratin, type I cytoskeletal 12 (Cytokeratin-12) (CK-12) (Keratin-12) (K12)" KRT12 Homo sapiens (Human) cornea development in camera-type eye [GO:0061303]; epithelial cell differentiation [GO:0030855]; intermediate filament organization [GO:0045109]; morphogenesis of an epithelium [GO:0002009]; visual perception [GO:0007601] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882] structural molecule activity [GO:0005198] 0.8621 0.096878 LASYLDK 0 0 0 0 0 10.8612 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.40578 0 0 0 0 0 10.0404 Q99457 NP1L3_HUMAN Nucleosome assembly protein 1-like 3 NAP1L3 BNAP Homo sapiens (Human) nucleosome assembly [GO:0006334] chromatin [GO:0000785]; nucleus [GO:0005634] chromatin binding [GO:0003682]; histone binding [GO:0042393] 0.95984 -1.9314 DVTVTTTQSR 9.41346 0 10.487 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q99459 CDC5L_HUMAN Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5-related protein) CDC5L KIAA0432 PCDC5RP Homo sapiens (Human) "cell cycle [GO:0007049]; DNA damage checkpoint signaling [GO:0000077]; DNA repair [GO:0006281]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]" catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Prp19 complex [GO:0000974]; spliceosomal complex [GO:0005681]; U2-type catalytic step 2 spliceosome [GO:0071007] "DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; WD40-repeat domain binding [GO:0071987]" 0.96198 -2.4878 DAERVKEMK 9.74143 0 0 0 0 0 0 11.1322 0 0 0 0 0 0 0 0 0 0 9.40593 0 0 0 0 0 0 0 0 Q99460 PSMD1_HUMAN 26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112) PSMD1 Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of protein catabolic process [GO:0042176] "azurophil granule lumen [GO:0035578]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome accessory complex [GO:0022624]; proteasome complex [GO:0000502]; proteasome regulatory particle [GO:0005838]; proteasome regulatory particle, base subcomplex [GO:0008540]; proteasome storage granule [GO:0034515]" enzyme regulator activity [GO:0030234]; ubiquitin protein ligase binding [GO:0031625] 0.42128 0.67156 QDVYDLLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.79484 0 0 0 0 0 0 0 0 Q99467 CD180_HUMAN CD180 antigen (Lymphocyte antigen 64) (Radioprotective 105 kDa protein) (CD antigen CD180) CD180 LY64 RP105 Homo sapiens (Human) B cell proliferation involved in immune response [GO:0002322]; cellular response to lipopolysaccharide [GO:0071222]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666] extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; mitotic spindle [GO:0072686]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] 0.93949 -1.3195 FPKDFPAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.18535 0 11.7326 0 0 0 0 0 0 0 0 0 0 Q99469 STAC_HUMAN SH3 and cysteine-rich domain-containing protein (Src homology 3 and cysteine-rich domain-containing protein) STAC STAC1 Homo sapiens (Human) cellular response to heat [GO:0034605]; positive regulation of cation channel activity [GO:2001259]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; signal transduction [GO:0007165]; skeletal muscle contraction [GO:0003009] cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; T-tubule [GO:0030315] metal ion binding [GO:0046872]; transmembrane transporter binding [GO:0044325] 0.56076 0.53384 AGLHPGGK 10.0664 10.0426 9.56921 0 0 0 0 0 0 0 0 0 0 0 9.02973 9.23033 0 9.13942 0 0 0 0 0 0 0 9.88679 0 Q99470 SDF2_HUMAN Stromal cell-derived factor 2 (SDF-2) SDF2 Homo sapiens (Human) chaperone cofactor-dependent protein refolding [GO:0051085] endoplasmic reticulum [GO:0005783]; protein folding chaperone complex [GO:0101031] misfolded protein binding [GO:0051787] 0.88492 -0.244 SATVCERGTPIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.43692 Q99471 PFD5_HUMAN Prefoldin subunit 5 (Myc modulator 1) (c-Myc-binding protein Mm-1) PFDN5 MM1 PFD5 Homo sapiens (Human) negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of DNA-templated transcription [GO:0045892]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; regulation of DNA-templated transcription [GO:0006355]; retina development in camera-type eye [GO:0060041]; RNA polymerase I assembly [GO:1990113]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase III assembly [GO:1990115] cytoplasm [GO:0005737]; cytosol [GO:0005829]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; prefoldin complex [GO:0016272] amyloid-beta binding [GO:0001540]; transcription corepressor activity [GO:0003714]; unfolded protein binding [GO:0051082] 0.95459 -1.522 IDFLTKQMEK 0 0 0 0 0 0 0 0 0 0 0 0 10.0982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q99490 AGAP2_HUMAN "Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (AGAP-2) (Centaurin-gamma-1) (Cnt-g1) (GTP-binding and GTPase-activating protein 2) (GGAP2) (Phosphatidylinositol 3-kinase enhancer) (PIKE)" AGAP2 CENTG1 KIAA0167 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; activation of GTPase activity [GO:0090630]; endosomal transport [GO:0016197]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein catabolic process [GO:0042177]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of protein kinase activity [GO:0045860]; protein transport [GO:0015031] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; GTP binding [GO:0005525]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; phosphatidylinositol 3-kinase regulator activity [GO:0035014]; protein kinase activator activity [GO:0030295]; protein kinase binding [GO:0019901] 0.89785 -0.56162 LTTPSKTEGSAGQAEAK 0 0 10.4065 0 0 0 0 0 0 0 0 0 10.1107 0 0 10.4704 0 0 0 0 0 0 0 0 0 0 0 Q99497 PARK7_HUMAN "Parkinson disease protein 7 (Maillard deglycase) (Oncogene DJ1) (Parkinsonism-associated deglycase) (Protein DJ-1) (DJ-1) (Protein/nucleic acid deglycase DJ-1) (EC 3.1.2.-, EC 3.5.1.-, EC 3.5.1.124)" PARK7 Homo sapiens (Human) "activation of protein kinase B activity [GO:0032148]; adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular detoxification of aldehyde [GO:0110095]; cellular detoxification of methylglyoxal [GO:0140041]; cellular response to glyoxal [GO:0036471]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; detection of oxidative stress [GO:0070994]; detoxification of copper ion [GO:0010273]; detoxification of hydrogen peroxide [GO:0061691]; detoxification of mercury ion [GO:0050787]; DNA repair [GO:0006281]; dopamine uptake involved in synaptic transmission [GO:0051583]; glucose homeostasis [GO:0042593]; glutathione deglycation [GO:0036531]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; lactate biosynthetic process [GO:0019249]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal catabolic process to lactate [GO:0061727]; methylglyoxal metabolic process [GO:0009438]; mitochondrion organization [GO:0007005]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of death-inducing signaling complex assembly [GO:1903073]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; peptidyl-arginine deglycation [GO:0036527]; peptidyl-cysteine deglycation [GO:0036526]; peptidyl-lysine deglycation [GO:0036528]; positive regulation of acute inflammatory response to antigenic stimulus [GO:0002866]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of L-dopa decarboxylase activity [GO:1903200]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein-containing complex assembly [GO:0031334]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tyrosine 3-monooxygenase activity [GO:1903178]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycation, methylglyoxal removal [GO:0036530]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; proteolysis [GO:0006508]; Ras protein signal transduction [GO:0007265]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of supramolecular fiber organization [GO:1902903]; response to oxidative stress [GO:0006979]; single fertilization [GO:0007338]" adherens junction [GO:0005912]; axon [GO:0030424]; cell body [GO:0044297]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; PML body [GO:0016605]; presynapse [GO:0098793] "cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; cytokine binding [GO:0019955]; DNA-binding transcription factor binding [GO:0140297]; enzyme binding [GO:0019899]; glyoxalase (glycolic acid-forming) activity [GO:1990422]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-dopa decarboxylase activator activity [GO:0036478]; mercury ion binding [GO:0045340]; mRNA binding [GO:0003729]; nuclear androgen receptor binding [GO:0050681]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; oxygen sensor activity [GO:0019826]; peptidase activity [GO:0008233]; peroxiredoxin activity [GO:0051920]; protein deglycase activity [GO:0036524]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; small protein activating enzyme binding [GO:0044388]; superoxide dismutase copper chaperone activity [GO:0016532]; transcription coactivator activity [GO:0003713]; tyrosine 3-monooxygenase activator activity [GO:0036470]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; ubiquitin-specific protease binding [GO:1990381]" 0 4.6186 ALVILAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.43131 9.1499 9.57601 9.45863 9.24051 9.57257 11.152 11.5374 11.2574 Q99501 GA2L1_HUMAN GAS2-like protein 1 (GAS2-related protein on chromosome 22) (Growth arrest-specific protein 2-like 1) GAS2L1 GAR22 Homo sapiens (Human) actin crosslink formation [GO:0051764]; cellular response to starvation [GO:0009267]; cellular response to thyroid hormone stimulus [GO:0097067]; microtubule bundle formation [GO:0001578]; negative regulation of cell growth [GO:0030308]; negative regulation of erythrocyte differentiation [GO:0045647]; negative regulation of gene expression [GO:0010629]; negative regulation of microtubule depolymerization [GO:0007026]; protein localization to microtubule plus-end [GO:1904825]; regulation of cell cycle [GO:0051726]; regulation of microtubule polymerization or depolymerization [GO:0031110] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856] actin filament binding [GO:0051015]; cytoskeletal anchor activity [GO:0008093]; microtubule binding [GO:0008017]; nuclear thyroid hormone receptor binding [GO:0046966] 0.88357 -0.14331 VGGGWDTLEHYLDK 0 0 0 0 0 0 0 0 0 9.36337 0 0 0 9.07103 0 0 0 0 0 0 0 0 0 0 0 0 0 Q99527 GPER1_HUMAN G-protein coupled estrogen receptor 1 (Chemoattractant receptor-like 2) (Flow-induced endothelial G-protein coupled receptor 1) (FEG-1) (G protein-coupled estrogen receptor 1) (G-protein coupled receptor 30) (GPCR-Br) (IL8-related receptor DRY12) (Lymphocyte-derived G-protein coupled receptor) (LYGPR) (Membrane estrogen receptor) (mER) GPER1 CEPR CMKRL2 DRY12 GPER GPR30 Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; apoptotic chromosome condensation [GO:0030263]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cellular response to estradiol stimulus [GO:0071392]; cellular response to glucose stimulus [GO:0071333]; cellular response to mineralocorticoid stimulus [GO:0071389]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to tumor necrosis factor [GO:0071356]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intracellular steroid hormone receptor signaling pathway [GO:0030518]; negative regulation of cell cycle process [GO:0010948]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of leukocyte activation [GO:0002695]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; nervous system development [GO:0007399]; neuronal action potential [GO:0019228]; nuclear fragmentation involved in apoptotic nuclear change [GO:0030264]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac vascular smooth muscle cell differentiation [GO:2000724]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of gene expression [GO:0010628]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of insulin secretion [GO:0032024]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neurogenesis [GO:0050769]; positive regulation of neurotransmitter secretion [GO:0001956]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of uterine smooth muscle contraction [GO:0070474]; regulation of cell cycle [GO:0051726]; regulation of cytosolic calcium ion concentration [GO:0051480]; steroid hormone mediated signaling pathway [GO:0043401]; vasodilation [GO:0042311] axon [GO:0030424]; axon terminus [GO:0043679]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine head [GO:0044327]; dendritic spine membrane [GO:0032591]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; intracellular membrane-bounded organelle [GO:0043231]; keratin filament [GO:0045095]; mitochondrial membrane [GO:0031966]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynaptic active zone [GO:0048786]; presynaptic membrane [GO:0042734]; recycling endosome [GO:0055037]; trans-Golgi network [GO:0005802] chromatin binding [GO:0003682]; G protein-coupled estrogen receptor activity [GO:0038054]; G protein-coupled receptor activity [GO:0004930]; nuclear estrogen receptor activity [GO:0030284]; steroid binding [GO:0005496]; steroid hormone binding [GO:1990239] 0.93223 -1.2874 AMRCSLFRTK 0 0 0 0 0 0 0 0 0 8.5941 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q99536 VAT1_HUMAN Synaptic vesicle membrane protein VAT-1 homolog (EC 1.-.-.-) VAT1 Homo sapiens (Human) negative regulation of mitochondrial fusion [GO:0010637] azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741] oxidoreductase activity [GO:0016491]; zinc ion binding [GO:0008270] 0.57486 0.47354 TVENVTVFGTASASK 0 0 0 0 0 0 8.00949 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q99538 LGMN_HUMAN "Legumain (EC 3.4.22.34) (Asparaginyl endopeptidase) (Protease, cysteine 1)" LGMN PRSC1 Homo sapiens (Human) activation of cysteine-type endopeptidase activity [GO:0097202]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; associative learning [GO:0008306]; cellular response to amyloid-beta [GO:1904646]; cellular response to calcium ion [GO:0071277]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; dendritic spine organization [GO:0097061]; memory [GO:0007613]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of gene expression [GO:0010629]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; receptor catabolic process [GO:0032801]; renal system process [GO:0003014]; response to acidic pH [GO:0010447]; self proteolysis [GO:0097264]; vacuolar protein processing [GO:0006624]; vitamin D metabolic process [GO:0042359] apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; perinuclear region of cytoplasm [GO:0048471] cysteine-type endopeptidase activity [GO:0004197]; peptidase activity [GO:0008233]; tau protein binding [GO:0048156] 0.89711 -0.52737 ESSYACYYDEK 0 0 0 0 0 0 11.2449 12.4245 0 0 0 0 0 0 0 0 0 0 0 0 0 9.90506 0 0 0 0 0 Q99541 PLIN2_HUMAN Perilipin-2 (Adipophilin) (Adipose differentiation-related protein) (ADRP) PLIN2 ADFP Homo sapiens (Human) cellular response to glucose starvation [GO:0042149]; lipid droplet disassembly [GO:1905691]; lipid storage [GO:0019915]; long-chain fatty acid transport [GO:0015909]; positive regulation of sequestering of triglyceride [GO:0010890]; response to organic cyclic compound [GO:0014070]; response to xenobiotic stimulus [GO:0009410] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; lipid droplet [GO:0005811]; nucleus [GO:0005634]; plasma membrane [GO:0005886] 0.96184 -2.5603 GAVTGAK 0 0 0 0 0 0 0 8.96852 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q99542 MMP19_HUMAN Matrix metalloproteinase-19 (MMP-19) (EC 3.4.24.-) (Matrix metalloproteinase RASI) (Matrix metalloproteinase-18) (MMP-18) MMP19 MMP18 RASI Homo sapiens (Human) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; luteolysis [GO:0001554]; ovarian follicle development [GO:0001541]; ovulation from ovarian follicle [GO:0001542]; proteolysis [GO:0006508]; response to cAMP [GO:0051591]; response to hormone [GO:0009725] extracellular matrix [GO:0031012]; extracellular region [GO:0005576] metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270] 0.88406 -0.25667 MSPGFPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5038 0 0 Q99543 DNJC2_HUMAN "DnaJ homolog subfamily C member 2 (M-phase phosphoprotein 11) (Zuotin-related factor 1) [Cleaved into: DnaJ homolog subfamily C member 2, N-terminally processed]" DNAJC2 MPHOSPH11 MPP11 ZRF1 Homo sapiens (Human) 'de novo' cotranslational protein folding [GO:0051083]; chromatin organization [GO:0006325]; DNA replication [GO:0006260]; negative regulation of DNA biosynthetic process [GO:2000279]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cellular response to heat [GO:1900034]; regulation of translational fidelity [GO:0006450] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATPase activator activity [GO:0001671]; chromatin binding [GO:0003682]; histone binding [GO:0042393]; Hsp70 protein binding [GO:0030544]; ribosome binding [GO:0043022]; RNA binding [GO:0003723]; ubiquitin modification-dependent histone binding [GO:0061649] 0.94737 -1.3476 ELVEMVKAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.21233 0 0 0 0 0 0 0 0 Q99550 MPP9_HUMAN M-phase phosphoprotein 9 MPHOSPH9 MPP9 Homo sapiens (Human) negative regulation of cilium assembly [GO:1902018] centriole [GO:0005814]; centrosome [GO:0005813]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020] 0.95966 -1.8212 DALNTTENKLLDAYTQISDLK 9.30047 0 0 0 0 0 9.86006 0 0 0 10.0885 0 0 0 0 0 0 0 10.2016 0 0 0 0 0 0 8.63147 0 Q99558 M3K14_HUMAN Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF-kappa-beta-inducing kinase) (HsNIK) (Serine/threonine-protein kinase NIK) MAP3K14 NIK Homo sapiens (Human) cellular response to mechanical stimulus [GO:0071260]; defense response to virus [GO:0051607]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein phosphorylation [GO:0006468] cytosol [GO:0005829]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654] ATP binding [GO:0005524]; MAP kinase kinase kinase activity [GO:0004709]; NF-kappaB-inducing kinase activity [GO:0004704]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.95423 -1.5328 APGPRPAEETTGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.703 0 0 0 0 0 0 0 0 0 0 0 0 Q99569 PKP4_HUMAN Plakophilin-4 (p0071) PKP4 Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cell-cell junction assembly [GO:0007043]; cell-cell signaling [GO:0007267]; positive regulation of cytokinesis [GO:0032467]; positive regulation of GTPase activity [GO:0043547]; regulation of cell adhesion [GO:0030155] adherens junction [GO:0005912]; cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytoskeleton [GO:0005856]; desmosome [GO:0030057]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; spindle midzone [GO:0051233]; spindle pole [GO:0000922] cadherin binding [GO:0045296] 0.72197 0.35972 LGAESPSIASTSSTEK 0 0 0 0 0 0 10.7683 0 0 0 0 0 9.76717 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q99570 PI3R4_HUMAN Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) PIK3R4 VPS15 Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] "autophagosome [GO:0005776]; axoneme [GO:0005930]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; nucleus-vacuole junction [GO:0071561]; phagocytic vesicle membrane [GO:0030670]; phosphatidylinositol 3-kinase complex, class III [GO:0035032]; phosphatidylinositol 3-kinase complex, class III, type I [GO:0034271]; phosphatidylinositol 3-kinase complex, class III, type II [GO:0034272]" ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.88221 -0.072132 ETFLSADER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.07551 0 Q99571 P2RX4_HUMAN P2X purinoceptor 4 (P2X4) (ATP receptor) (Purinergic receptor) P2RX4 Homo sapiens (Human) apoptotic signaling pathway [GO:0097190]; behavioral response to pain [GO:0048266]; calcium ion transmembrane transport [GO:0070588]; calcium-mediated signaling [GO:0019722]; cellular response to ATP [GO:0071318]; cellular response to zinc ion [GO:0071294]; endothelial cell activation [GO:0042118]; membrane depolarization [GO:0051899]; monoatomic ion transmembrane transport [GO:0034220]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; neuronal action potential [GO:0019228]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of microglial cell migration [GO:1904141]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein kinase B signaling [GO:0051897]; purinergic nucleotide receptor signaling pathway [GO:0035590]; regulation of blood pressure [GO:0008217]; regulation of cardiac muscle contraction [GO:0055117]; regulation of chemotaxis [GO:0050920]; regulation of sodium ion transport [GO:0002028]; relaxation of cardiac muscle [GO:0055119]; response to ATP [GO:0033198]; response to axon injury [GO:0048678]; response to fluid shear stress [GO:0034405]; response to ischemia [GO:0002931]; sensory perception of pain [GO:0019233]; sensory perception of touch [GO:0050975]; signal transduction [GO:0007165]; tissue homeostasis [GO:0001894] cell body [GO:0044297]; cell junction [GO:0030054]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; terminal bouton [GO:0043195] ATP binding [GO:0005524]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; extracellularly ATP-gated monoatomic cation channel activity [GO:0004931]; identical protein binding [GO:0042802]; ligand-gated calcium channel activity [GO:0099604]; purinergic nucleotide receptor activity [GO:0001614]; signaling receptor binding [GO:0005102]; zinc ion binding [GO:0008270] 0.93366 -1.2829 NNIWYPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.36385 0 0 0 0 0 0 0 0 0 0 0 Q99572 P2RX7_HUMAN P2X purinoceptor 7 (P2X7) (ATP receptor) (P2Z receptor) (Purinergic receptor) P2RX7 Homo sapiens (Human) apoptotic signaling pathway [GO:0097190]; bleb assembly [GO:0032060]; calcium ion transmembrane transport [GO:0070588]; calcium-mediated signaling using extracellular calcium source [GO:0035585]; cell morphogenesis [GO:0000902]; cell surface receptor signaling pathway [GO:0007166]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular response to ATP [GO:0071318]; cellular response to dsRNA [GO:0071359]; cellular response to extracellular stimulus [GO:0031668]; ceramide biosynthetic process [GO:0046513]; collagen metabolic process [GO:0032963]; defense response to Gram-positive bacterium [GO:0050830]; extrinsic apoptotic signaling pathway [GO:0097191]; gamma-aminobutyric acid secretion [GO:0014051]; glutamate secretion [GO:0014047]; homeostasis of number of cells within a tissue [GO:0048873]; inflammatory response [GO:0006954]; MAPK cascade [GO:0000165]; membrane depolarization [GO:0051899]; membrane protein ectodomain proteolysis [GO:0006509]; mitochondrial depolarization [GO:0051882]; mitochondrion organization [GO:0007005]; NAD transport [GO:0043132]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell volume [GO:0045794]; negative regulation of MAPK cascade [GO:0043409]; phagolysosome assembly [GO:0001845]; phospholipid transfer to membrane [GO:0006649]; plasma membrane phospholipid scrambling [GO:0017121]; pore complex assembly [GO:0046931]; positive regulation of bleb assembly [GO:1904172]; positive regulation of bone mineralization [GO:0030501]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cytoskeleton organization [GO:0051495]; positive regulation of gamma-aminobutyric acid secretion [GO:0014054]; positive regulation of gene expression [GO:0010628]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of glycolytic process [GO:0045821]; positive regulation of interleukin-1 alpha production [GO:0032730]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of monoatomic ion transmembrane transport [GO:0034767]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein secretion [GO:0050714]; positive regulation of T cell apoptotic process [GO:0070234]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; prostaglandin secretion [GO:0032310]; protein catabolic process [GO:0030163]; protein phosphorylation [GO:0006468]; protein processing [GO:0016485]; protein secretion [GO:0009306]; purinergic nucleotide receptor signaling pathway [GO:0035590]; reactive oxygen species metabolic process [GO:0072593]; regulation of killing of cells of another organism [GO:0051709]; regulation of sodium ion transport [GO:0002028]; release of sequestered calcium ion into cytosol [GO:0051209]; response to ATP [GO:0033198]; response to calcium ion [GO:0051592]; response to electrical stimulus [GO:0051602]; response to fluid shear stress [GO:0034405]; response to ischemia [GO:0002931]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to xenobiotic stimulus [GO:0009410]; response to zinc ion [GO:0010043]; sensory perception of pain [GO:0019233]; skeletal system morphogenesis [GO:0048705]; synaptic vesicle exocytosis [GO:0016079]; T cell apoptotic process [GO:0070231]; T cell homeostasis [GO:0043029]; T cell mediated cytotoxicity [GO:0001913]; T cell proliferation [GO:0042098]; vesicle budding from membrane [GO:0006900] bleb [GO:0032059]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; membrane [GO:0016020]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; presynapse [GO:0098793] ATP binding [GO:0005524]; extracellularly ATP-gated monoatomic cation channel activity [GO:0004931]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; purinergic nucleotide receptor activity [GO:0001614]; signaling receptor binding [GO:0005102] 0.96411 -2.2623 FGSQDMADFAILPSCCRWRIR 8.68654 10.0256 0 0 0 0 0 0 0 10.7624 10.049 0 0 0 9.26155 0 0 0 0 0 0 0 0 0 0 0 0 Q99575 POP1_HUMAN Ribonucleases P/MRP protein subunit POP1 (hPOP1) POP1 KIAA0061 Homo sapiens (Human) "RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; tRNA 5'-leader removal [GO:0001682]; tRNA catabolic process [GO:0016078]; tRNA processing [GO:0008033]" extracellular space [GO:0005615]; multimeric ribonuclease P complex [GO:0030681]; nucleolar ribonuclease P complex [GO:0005655]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; ribonuclease MRP complex [GO:0000172] ribonuclease P activity [GO:0004526]; ribonuclease P RNA binding [GO:0033204]; RNA binding [GO:0003723] 0.96731 -3.7678 AGPEGTSQEIPK 9.12337 10.5641 9.61532 9.24498 0 0 9.2056 0 9.16531 9.94689 9.68963 9.99676 0 0 0 11.3472 0 0 9.87093 0 9.44702 0 0 9.53611 10.0391 0 0 Q99576 T22D3_HUMAN TSC22 domain family protein 3 (DSIP-immunoreactive peptide) (Protein DIP) (hDIP) (Delta sleep-inducing peptide immunoreactor) (Glucocorticoid-induced leucine zipper protein) (GILZ) (TSC-22-like protein) (TSC-22-related protein) (TSC-22R) TSC22D3 DSIPI GILZ Homo sapiens (Human) negative regulation of activation-induced cell death of T cells [GO:0070236]; regulation of transcription by RNA polymerase II [GO:0006357]; response to osmotic stress [GO:0006970] cytosol [GO:0005829]; nucleus [GO:0005634] 0.86995 0.034467 TLASPEQLEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.83355 0 0 0 0 0 Q99581 FEV_HUMAN Protein FEV (Fifth Ewing variant protein) (PC12 ETS domain-containing transcription factor 1) (PC12 ETS factor 1) (Pet-1) FEV PET1 Homo sapiens (Human) neuron fate specification [GO:0048665]; neuron maturation [GO:0042551]; positive regulation of gene expression [GO:0010628]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nuclear speck [GO:0016607]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96404 -2.3916 ALRYYYDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2074 0 0 0 0 0 0 0 0 Q99583 MNT_HUMAN Max-binding protein MNT (Class D basic helix-loop-helix protein 3) (bHLHd3) (Myc antagonist MNT) (Protein ROX) MNT BHLHD3 ROX Homo sapiens (Human) cellular senescence [GO:0090398]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of cell cycle [GO:0051726]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] chromatin [GO:0000785]; nucleoplasm [GO:0005654] "chromatin binding [GO:0003682]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; protein dimerization activity [GO:0046983]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.89053 -0.46147 ECFETLK 0 0 0 0 0 0 9.42842 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q99590 SCAFB_HUMAN "Protein SCAF11 (CTD-associated SR protein 11) (Renal carcinoma antigen NY-REN-40) (SC35-interacting protein 1) (SR-related and CTD-associated factor 11) (SRSF2-interacting protein) (Serine/arginine-rich splicing factor 2-interacting protein) (Splicing factor, arginine/serine-rich 2-interacting protein) (Splicing regulatory protein 129) (SRrp129)" SCAF11 CASP11 SFRS2IP SIP1 SRSF2IP Homo sapiens (Human) "mRNA processing [GO:0006397]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal complex assembly [GO:0000245]" nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] metal ion binding [GO:0046872]; RNA binding [GO:0003723] 0.9696 -4.6766 ETSRENKR 0 0 0 0 0 10.3242 0 0 13.2 0 0 0 9.15919 0 0 10.2724 0 0 0 0 0 0 0 10.8175 0 10.8765 0 Q99593 TBX5_HUMAN T-box transcription factor TBX5 (T-box protein 5) TBX5 Homo sapiens (Human) atrial septum morphogenesis [GO:0060413]; atrioventricular bundle cell differentiation [GO:0003167]; atrioventricular node cell development [GO:0060928]; atrioventricular node cell fate commitment [GO:0060929]; atrioventricular valve morphogenesis [GO:0003181]; bundle of His cell to Purkinje myocyte communication by electrical coupling [GO:0086054]; bundle of His development [GO:0003166]; cardiac left ventricle formation [GO:0003218]; cardiac muscle cell proliferation [GO:0060038]; cell fate specification [GO:0001708]; cell migration involved in coronary vasculogenesis [GO:0060980]; cell-cell signaling [GO:0007267]; cell-cell signaling involved in cardiac conduction [GO:0086019]; embryonic forelimb morphogenesis [GO:0035115]; embryonic limb morphogenesis [GO:0030326]; endocardial cushion development [GO:0003197]; forelimb morphogenesis [GO:0035136]; heart development [GO:0007507]; lung development [GO:0030324]; morphogenesis of an epithelium [GO:0002009]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; pattern specification process [GO:0007389]; pericardium development [GO:0060039]; positive regulation of cardiac conduction [GO:1903781]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardioblast differentiation [GO:0051891]; positive regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901846]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of secondary heart field cardioblast proliferation [GO:0072513]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of atrial cardiac muscle cell membrane depolarization [GO:0060371]; regulation of transcription by RNA polymerase II [GO:0006357]; sinoatrial node development [GO:0003163]; transcription by RNA polymerase II [GO:0006366]; ventricular septum development [GO:0003281] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; transcription regulator complex [GO:0005667] "DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific DNA binding [GO:0043565]" 0.86504 0.078319 EEECSTTDHPYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7508 0 10.6079 0 0 0 0 0 0 0 0 0 Q99594 TEAD3_HUMAN Transcriptional enhancer factor TEF-5 (DTEF-1) (TEA domain family member 3) (TEAD-3) TEAD3 TEAD5 TEF5 Homo sapiens (Human) asymmetric neuroblast division [GO:0055059]; embryonic organ development [GO:0048568]; female pregnancy [GO:0007565]; hippo signaling [GO:0035329]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; transcription regulator complex [GO:0005667] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]" 0.95428 -1.5014 AMNLDQVSKDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.5922 0 0 0 Q99598 TSNAX_HUMAN Translin-associated protein X (Translin-associated factor X) TSNAX TRAX Homo sapiens (Human) cell differentiation [GO:0030154]; siRNA processing [GO:0030422]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoribonuclease complex [GO:1902555]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] A2A adenosine receptor binding [GO:0031687]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA endonuclease activity [GO:0004521]; sequence-specific DNA binding [GO:0043565]; single-stranded DNA binding [GO:0003697] 0.92947 -1.2309 ITSAPDMEDILTESEIK 0 0 0 0 0 0 0 0 0 9.96622 0 0 0 0 0 0 9.44137 0 0 0 0 0 0 0 0 0 0 Q99613 EIF3C_HUMAN Eukaryotic translation initiation factor 3 subunit C (eIF3c) (Eukaryotic translation initiation factor 3 subunit 8) (eIF3 p110) EIF3C EIF3S8 Homo sapiens (Human) formation of cytoplasmic translation initiation complex [GO:0001732]; positive regulation of mRNA binding [GO:1902416]; positive regulation of translation [GO:0045727]; translational initiation [GO:0006413] cytosol [GO:0005829]; eukaryotic 43S preinitiation complex [GO:0016282]; eukaryotic 48S preinitiation complex [GO:0033290]; eukaryotic translation initiation factor 3 complex [GO:0005852] ribosome binding [GO:0043022]; RNA binding [GO:0003723]; translation initiation factor activity [GO:0003743]; translation initiation factor binding [GO:0031369] 0.96798 -2.913 NNAKALSTLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.91616 0 0 0 Q99615 DNJC7_HUMAN DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2) DNAJC7 TPR2 TTC2 Homo sapiens (Human) chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; regulation of cellular response to heat [GO:1900034] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654] ATPase activator activity [GO:0001671]; heat shock protein binding [GO:0031072] 0.11797 1.1044 LDDSFVR 0 9.89582 0 0 0 0 11.0088 11.4313 0 0 0 0 0 0 0 0 0 11.4086 0 0 0 0 0 0 0 0 0 Q99622 C10_HUMAN Protein C10 C12orf57 C10 Homo sapiens (Human) camera-type eye morphogenesis [GO:0048593]; cognition [GO:0050890]; corpus callosum morphogenesis [GO:0021540]; post-embryonic development [GO:0009791]; psychomotor behavior [GO:0036343]; regulation of skeletal muscle contraction [GO:0014819]; third ventricle development [GO:0021678] cytoplasm [GO:0005737]; nuclear speck [GO:0016607] 0.84773 0.12708 MASASTQPAALSAEQAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4353 0 0 0 0 0 0 0 0 0 Q99623 PHB2_HUMAN Prohibitin-2 (B-cell receptor-associated protein BAP37) (D-prohibitin) (Repressor of estrogen receptor activity) PHB2 BAP REA Homo sapiens (Human) activation of phospholipase C activity [GO:0007202]; activation of protein kinase C activity [GO:1990051]; antiviral innate immune response [GO:0140374]; B cell activation [GO:0042113]; CD40 signaling pathway [GO:0023035]; cell migration [GO:0016477]; cellular response to hypoxia [GO:0071456]; cellular response to retinoic acid [GO:0071300]; intracellular estrogen receptor signaling pathway [GO:0030520]; mammary gland alveolus development [GO:0060749]; mammary gland branching involved in thelarche [GO:0060744]; mammary gland epithelial cell proliferation [GO:0033598]; mitochondrion organization [GO:0007005]; mitophagy [GO:0000423]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exit from mitosis [GO:0031536]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; protein import into nucleus [GO:0006606]; protein stabilization [GO:0050821]; regulation of branching involved in mammary gland duct morphogenesis [GO:0060762]; regulation of cardiolipin metabolic process [GO:1900208]; regulation of cytochrome-c oxidase activity [GO:1904959]; response to wounding [GO:0009611]; RIG-I signaling pathway [GO:0039529]; sister chromatid cohesion [GO:0007062] axon [GO:0030424]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; mitochondrial inner membrane [GO:0005743]; mitochondrial outer membrane [GO:0005741]; mitochondrial prohibitin complex [GO:0035632]; mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991] amide binding [GO:0033218]; identical protein binding [GO:0042802]; nuclear estrogen receptor binding [GO:0030331]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; sphingolipid binding [GO:0046625] 0 8.3063 EYTAAVEAK 0 0 0 0 0 0 0 0 10.1737 0 9.62708 10.4205 11.8759 11.3893 11.131 11.4697 11.5406 11.8088 10.0208 10.3927 8.58368 9.83518 0 0 0 9.33849 9.25842 Q99640 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase) PKMYT1 MYT1 Homo sapiens (Human) G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; protein phosphorylation [GO:0006468]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of mitotic nuclear division [GO:0007088] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.78514 0.25914 LGHGSYGEVFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1018 0 0 0 0 0 0 0 0 Q99650 OSMR_HUMAN Oncostatin-M-specific receptor subunit beta (Interleukin-31 receptor subunit beta) (IL-31 receptor subunit beta) (IL-31R subunit beta) (IL-31R-beta) (IL-31RB) OSMR OSMRB Homo sapiens (Human) cytokine-mediated signaling pathway [GO:0019221]; oncostatin-M-mediated signaling pathway [GO:0038165]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of cell population proliferation [GO:0008284]; response to cytokine [GO:0034097] apical plasma membrane [GO:0016324]; external side of plasma membrane [GO:0009897]; oncostatin-M receptor complex [GO:0005900]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] ciliary neurotrophic factor receptor binding [GO:0005127]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838] 0.88479 -0.33031 DFSCETEDFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.7134 8.74806 0 0 0 0 0 Q99661 KIF2C_HUMAN Kinesin-like protein KIF2C (Kinesin-like protein 6) (Mitotic centromere-associated kinesin) (MCAK) KIF2C KNSL6 Homo sapiens (Human) attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; cell division [GO:0051301]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; metaphase plate congression [GO:0051310]; microtubule depolymerization [GO:0007019]; microtubule-based movement [GO:0007018]; mitotic metaphase plate congression [GO:0007080]; regulation of chromosome segregation [GO:0051983] "centrosome [GO:0005813]; chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; kinesin complex [GO:0005871]; kinetochore [GO:0000776]; membrane [GO:0016020]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; microtubule plus-end [GO:0035371]; nucleus [GO:0005634]; spindle [GO:0005819]" ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; centromeric DNA binding [GO:0019237]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777]; microtubule plus-end binding [GO:0051010] 0.88616 -0.36516 AESALAQQAK 9.8069 0 0 0 0 0 0 0 0 0 0 8.52783 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q99666 RGPD5_HUMAN RANBP2-like and GRIP domain-containing protein 5/6 (Ran-binding protein 2-like 1/2) (RanBP2-like 1/2) (RanBP2L1) (RanBP2L2) (Sperm membrane protein BS-63) RGPD5 RANBP2L1 RGP5 RGP7 RGPD7; RGPD6 RANBP2L2 RGP6 Homo sapiens (Human) NLS-bearing protein import into nucleus [GO:0006607] cytoplasm [GO:0005737]; nuclear pore [GO:0005643] 0.96778 -2.8986 DVGQWKER 0 0 0 0 0 0 0 0 9.38946 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q99674 CGRE1_HUMAN Cell growth regulator with EF hand domain protein 1 (Cell growth regulatory gene 11 protein) (Hydrophobestin) CGREF1 CGR11 Homo sapiens (Human) cell adhesion [GO:0007155]; cell cycle [GO:0007049]; negative regulation of cell population proliferation [GO:0008285]; regulation of cell cycle [GO:0051726] extracellular region [GO:0005576] calcium ion binding [GO:0005509] 0.96174 -2.5603 GDAPGPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.8989 0 0 0 Q99676 ZN184_HUMAN Zinc finger protein 184 ZNF184 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; zinc ion binding [GO:0008270] 0.96101 -2.0096 HQRLHPGI 0 0 10.1301 0 0 0 0 0 0 0 0 0 0 0 0 9.83988 0 0 0 0 0 0 0 0 0 0 0 Q99680 GPR22_HUMAN G-protein coupled receptor 22 GPR22 Homo sapiens (Human) cell projection organization [GO:0030030]; cellular response to hormone stimulus [GO:0032870]; G protein-coupled receptor signaling pathway [GO:0007186] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; peptide binding [GO:0042277] 0.87756 0.0031113 ITFEDSEIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.29951 0 0 0 0 0 0 0 0 0 0 Q99683 M3K5_HUMAN Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) MAP3K5 ASK1 MAPKKK5 MEKK5 Homo sapiens (Human) apoptotic signaling pathway [GO:0097190]; cellular response to amino acid starvation [GO:0034198]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to reactive nitrogen species [GO:1902170]; cellular response to tumor necrosis factor [GO:0071356]; cellular senescence [GO:0090398]; endothelial cell apoptotic process [GO:0072577]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; JNK cascade [GO:0007254]; MAPK cascade [GO:0000165]; p38MAPK cascade [GO:0038066]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neuron death [GO:1901216]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; programmed necrotic cell death [GO:0097300]; protein phosphorylation [GO:0006468]; response to endoplasmic reticulum stress [GO:0034976]; response to ischemia [GO:0002931]; stress-activated MAPK cascade [GO:0051403]; wound healing [GO:0042060] cytoplasm [GO:0005737]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; IRE1-TRAF2-ASK1 complex [GO:1990604]; protein kinase complex [GO:1902911]; protein-containing complex [GO:0032991] ATP binding [GO:0005524]; identical protein binding [GO:0042802]; JUN kinase kinase kinase activity [GO:0004706]; magnesium ion binding [GO:0000287]; MAP kinase kinase kinase activity [GO:0004709]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96894 -3.891 DHGASWFKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.76361 0 9.65821 0 0 0 0 0 0 0 10.6466 0 Q99684 GFI1_HUMAN Zinc finger protein Gfi-1 (Growth factor independent protein 1) (Zinc finger protein 163) GFI1 ZNF163 Homo sapiens (Human) cellular response to lipopolysaccharide [GO:0071222]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of neuron projection development [GO:0010977]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vitamin D biosynthetic process [GO:0010957]; positive regulation of interleukin-6-mediated signaling pathway [GO:0070105]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032] nuclear body [GO:0016604]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]; transcription repressor complex [GO:0017053] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]" 0.96065 -2.0138 HRETQHGLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.27633 0 0 0 0 0 0 0 Q99697 PITX2_HUMAN Pituitary homeobox 2 (ALL1-responsive protein ARP1) (Homeobox protein PITX2) (Paired-like homeodomain transcription factor 2) (RIEG bicoid-related homeobox transcription factor) (Solurshin) PITX2 ARP1 RGS RIEG RIEG1 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cardiac neural crest cell migration involved in outflow tract morphogenesis [GO:0003253]; cell proliferation involved in outflow tract morphogenesis [GO:0061325]; deltoid tuberosity development [GO:0035993]; determination of left/right symmetry [GO:0007368]; embryonic heart tube left/right pattern formation [GO:0060971]; hair cell differentiation [GO:0035315]; iris morphogenesis [GO:0061072]; left/right axis specification [GO:0070986]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; positive regulation of transcription by RNA polymerase II [GO:0045944]; prolactin secreting cell differentiation [GO:0060127]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; somatotropin secreting cell differentiation [GO:0060126]; spleen development [GO:0048536] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription factor binding [GO:0140297]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; phosphoprotein binding [GO:0051219]; protein homodimerization activity [GO:0042803]; ribonucleoprotein complex binding [GO:0043021]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]" 0.94118 -1.3127 EAASSKFFPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.68862 0 Q99698 LYST_HUMAN Lysosomal-trafficking regulator (Beige homolog) LYST CHS CHS1 Homo sapiens (Human) defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; leukocyte chemotaxis [GO:0030595]; mast cell secretory granule organization [GO:0033364]; melanosome organization [GO:0032438]; natural killer cell mediated cytotoxicity [GO:0042267]; phagocytosis [GO:0006909]; pigmentation [GO:0043473]; protein localization [GO:0008104]; protein transport [GO:0015031] cytosol [GO:0005829]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630] protein kinase binding [GO:0019901] 0.082692 1.2345 AICGLSRNFCLLMTYSK 0 0 0 0 0 0 0 9.12521 0 13.7389 0 0 0 0 9.74197 11.0856 0 0 0 0 0 0 0 10.2997 0 0 0 Q99704 DOK1_HUMAN Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)) (pp62) DOK1 Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; macrophage colony-stimulating factor signaling pathway [GO:0038145]; positive regulation of MAPK cascade [GO:0043410]; Ras protein signal transduction [GO:0007265]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] 0.89903 -0.61362 AQGKAGQGHDVLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1219 Q99705 MCHR1_HUMAN Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCH-R1) (MCHR-1) (G-protein coupled receptor 24) (MCH-1R) (MCH1R) (MCHR) (SLC-1) (Somatostatin receptor-like protein) MCHR1 GPR24 SLC1 Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; cell surface receptor signaling pathway [GO:0007166]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; generation of precursor metabolites and energy [GO:0006091]; neuropeptide signaling pathway [GO:0007218]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cytosolic calcium ion concentration [GO:0007204] ciliary membrane [GO:0060170]; cilium [GO:0005929]; neuron projection [GO:0043005]; non-motile cilium [GO:0097730]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; hormone binding [GO:0042562]; melanin-concentrating hormone receptor activity [GO:0030273]; neuropeptide receptor activity [GO:0008188]; signaling receptor binding [GO:0005102] 0.96123 -2.5603 MSVGAMK 0 0 0 0 0 0 0 0 7.52818 0 0 0 0 0 0 0 0 0 0 0 0 0 8.86648 8.17612 0 0 0 Q99706 KI2L4_HUMAN Killer cell immunoglobulin-like receptor 2DL4 (CD158 antigen-like family member D) (G9P) (Killer cell inhibitory receptor 103AS) (KIR-103AS) (MHC class I NK cell receptor KIR103AS) (CD antigen CD158d) KIR2DL4 CD158D KIR103AS Homo sapiens (Human) cellular defense response [GO:0006968]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; positive regulation of cellular senescence [GO:2000774]; positive regulation of natural killer cell cytokine production [GO:0002729]; signal transduction [GO:0007165] early endosome membrane [GO:0031901]; membrane [GO:0016020]; plasma membrane [GO:0005886] MHC class Ib receptor activity [GO:0032394]; transmembrane signaling receptor activity [GO:0004888] 0.96834 -3.649 ITGPSQR 14.4745 14.3927 14.3696 0 0 0 14.4398 14.5147 14.5902 0 0 0 0 0 0 9.79915 0 9.623 0 0 0 0 0 0 0 0 0 Q99707 METH_HUMAN Methionine synthase (MS) (EC 2.1.1.13) (5-methyltetrahydrofolate--homocysteine methyltransferase) (Cobalamin-dependent methionine synthase) (Vitamin-B12 dependent methionine synthase) MTR Homo sapiens (Human) axon regeneration [GO:0031103]; cellular response to nitric oxide [GO:0071732]; cobalamin metabolic process [GO:0009235]; homocysteine metabolic process [GO:0050667]; methionine biosynthetic process [GO:0009086]; methylation [GO:0032259]; nervous system development [GO:0007399]; response to axon injury [GO:0048678]; tetrahydrofolate metabolic process [GO:0046653] cytosol [GO:0005829] cobalamin binding [GO:0031419]; methionine synthase activity [GO:0008705]; zinc ion binding [GO:0008270] 0.95199 -1.4279 SKYFAVGK 0 0 0 0 0 0 10.4349 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q99708 CTIP_HUMAN DNA endonuclease RBBP8 (EC 3.1.-.-) (CtBP-interacting protein) (CtIP) (Retinoblastoma-binding protein 8) (RBBP-8) (Retinoblastoma-interacting protein and myosin-like) (RIM) (Sporulation in the absence of SPO11 protein 2 homolog) (SAE2) RBBP8 CTIP Homo sapiens (Human) blastocyst hatching [GO:0001835]; cell division [GO:0051301]; DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA repair [GO:0006281]; DNA strand resection involved in replication fork processing [GO:0110025]; double-strand break repair via homologous recombination [GO:0000724]; G1/S transition of mitotic cell cycle [GO:0000082]; homologous recombination [GO:0035825]; meiotic cell cycle [GO:0051321]; mitotic G2/M transition checkpoint [GO:0044818]; regulation of transcription by RNA polymerase II [GO:0006357] BRCA1-C complex [GO:0070533]; chromosome [GO:0005694]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription repressor complex [GO:0017053] damaged DNA binding [GO:0003684]; identical protein binding [GO:0042802]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; single-stranded DNA endodeoxyribonuclease activity [GO:0000014]; transcription corepressor activity [GO:0003714] 0.95905 -1.8761 EVQGLQVK 0 0 0 0 0 0 0 8.76467 12.0565 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q99712 KCJ15_HUMAN "ATP-sensitive inward rectifier potassium channel 15 (Inward rectifier K(+) channel Kir1.3) (Inward rectifier K(+) channel Kir4.2) (Potassium channel, inwardly rectifying subfamily J member 15)" KCNJ15 KCNJ14 Homo sapiens (Human) potassium ion import across plasma membrane [GO:1990573]; potassium ion transport [GO:0006813]; regulation of monoatomic ion transmembrane transport [GO:0034765] plasma membrane [GO:0005886] inward rectifier potassium channel activity [GO:0005242] 0.76151 0.29781 DLTPQNLK 0 0 0 0 0 0 0 0 0 0 0 0 0 8.30072 0 0 0 0 0 0 0 0 0 0 0 0 0 Q99714 HCD2_HUMAN 3-hydroxyacyl-CoA dehydrogenase type-2 (EC 1.1.1.35) (17-beta-estradiol 17-dehydrogenase) (EC 1.1.1.62) (2-methyl-3-hydroxybutyryl-CoA dehydrogenase) (MHBD) (3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))) (EC 1.1.1.239) (3-hydroxy-2-methylbutyryl-CoA dehydrogenase) (EC 1.1.1.178) (3-hydroxyacyl-CoA dehydrogenase type II) (3alpha(or 20beta)-hydroxysteroid dehydrogenase) (EC 1.1.1.53) (7-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.159) (Endoplasmic reticulum-associated amyloid beta-peptide-binding protein) (Mitochondrial ribonuclease P protein 2) (Mitochondrial RNase P protein 2) (Short chain dehydrogenase/reductase family 5C member 1) (Short-chain type dehydrogenase/reductase XH98G2) (Type II HADH) HSD17B10 ERAB HADH2 MRPP2 SCHAD SDR5C1 XH98G2 Homo sapiens (Human) androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; brexanolone metabolic process [GO:0062173]; C21-steroid hormone metabolic process [GO:0008207]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; fatty acid metabolic process [GO:0006631]; isoleucine catabolic process [GO:0006550]; lipid metabolic process [GO:0006629]; mitochondrial tRNA 3'-end processing [GO:1990180]; mitochondrial tRNA 5'-end processing [GO:0097745]; mitochondrial tRNA methylation [GO:0070901]; mitochondrion organization [GO:0007005]; protein homotetramerization [GO:0051289] cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrial ribonuclease P complex [GO:0030678]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; tRNA methyltransferase complex [GO:0043527] "17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity [GO:0047015]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; androstan-3-alpha,17-beta-diol dehydrogenase activity [GO:0047044]; chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity [GO:0106281]; cholate 7-alpha-dehydrogenase activity [GO:0008709]; estradiol 17-beta-dehydrogenase [NAD(P)] activity [GO:0004303]; isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity [GO:0106282]; RNA binding [GO:0003723]; testosterone dehydrogenase (NAD+) activity [GO:0047035]; testosterone dehydrogenase [NAD(P)] activity [GO:0030283]; tRNA binding [GO:0000049]; ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity [GO:0106283]" 0 7.1668 GGIVGMTLPIAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.79594 0 10.6214 9.98085 10.3049 11.0858 10.6285 10.1941 11.3264 10.952 10.9915 Q99715 COCA1_HUMAN Collagen alpha-1(XII) chain COL12A1 COL12A1L Homo sapiens (Human) cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; endodermal cell differentiation [GO:0035987] collagen type XII trimer [GO:0005595]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561] extracellular matrix structural constituent conferring tensile strength [GO:0030020] 0.95104 -1.4356 GLPGEKGER 0 0 8.69738 0 9.25366 9.8507 11.131 0 10.5322 0 10.6813 11.073 11.5512 12.0847 0 0 0 0 10.0501 0 0 0 0 0 0 0 0 Q99717 SMAD5_HUMAN Mothers against decapentaplegic homolog 5 (MAD homolog 5) (Mothers against DPP homolog 5) (JV5-1) (SMAD family member 5) (SMAD 5) (Smad5) (hSmad5) SMAD5 MADH5 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; BMP signaling pathway [GO:0030509]; bone development [GO:0060348]; cardiac conduction system development [GO:0003161]; cardiac muscle contraction [GO:0060048]; cartilage development [GO:0051216]; cell differentiation [GO:0030154]; cellular response to organic cyclic compound [GO:0071407]; embryonic pattern specification [GO:0009880]; erythrocyte differentiation [GO:0030218]; germ cell development [GO:0007281]; Mullerian duct regression [GO:0001880]; negative regulation of apoptotic process [GO:0043066]; negative regulation of Fas signaling pathway [GO:1902045]; negative regulation of gene expression [GO:0010629]; osteoblast fate commitment [GO:0002051]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; protein phosphorylation [GO:0006468]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ureteric bud development [GO:0001657] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; heteromeric SMAD protein complex [GO:0071144]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; SMAD protein complex [GO:0071141] "DEAD/H-box RNA helicase binding [GO:0017151]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; I-SMAD binding [GO:0070411]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]; ubiquitin protein ligase binding [GO:0031625]" 0.79966 0.23919 DVQPVAYEEPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.84048 0 0 0 0 0 0 0 0 0 0 Q99719 SEPT5_HUMAN Septin-5 (Cell division control-related protein 1) (CDCrel-1) (Peanut-like protein 1) SEPTIN5 PNUTL1 SEPT5 Homo sapiens (Human) adult behavior [GO:0030534]; cytoskeleton-dependent cytokinesis [GO:0061640]; regulation of exocytosis [GO:0017157]; regulation of synaptic vesicle exocytosis [GO:2000300]; social behavior [GO:0035176]; synaptic vesicle targeting [GO:0016080] cell division site [GO:0032153]; microtubule cytoskeleton [GO:0015630]; plasma membrane [GO:0005886]; septin complex [GO:0031105]; septin ring [GO:0005940]; synaptic vesicle [GO:0008021] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; molecular adaptor activity [GO:0060090]; structural molecule activity [GO:0005198] 0.92303 -1.1513 LYPWGIVEVENQAHCDFVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8119 0 0 0 0 0 Q99728 BARD1_HUMAN BRCA1-associated RING domain protein 1 (BARD-1) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase BARD1) BARD1 Homo sapiens (Human) cellular response to ionizing radiation [GO:0071479]; DNA damage response [GO:0006974]; DNA repair [GO:0006281]; DNA strand resection involved in replication fork processing [GO:0110025]; histone H2A K63-linked deubiquitination [GO:0070537]; histone H2A monoubiquitination [GO:0035518]; homologous recombination [GO:0035825]; mitotic G2/M transition checkpoint [GO:0044818]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle [GO:0045786]; negative regulation of mRNA 3'-end processing [GO:0031441]; negative regulation of protein export from nucleus [GO:0046826]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein catabolic process [GO:0045732]; protein autoubiquitination [GO:0051865]; protein K6-linked ubiquitination [GO:0085020]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; regulation of DNA damage checkpoint [GO:2000001]; regulation of DNA repair [GO:0006282]; regulation of phosphorylation [GO:0042325]; tissue homeostasis [GO:0001894] BRCA1-A complex [GO:0070531]; BRCA1-B complex [GO:0070532]; BRCA1-BARD1 complex [GO:0031436]; BRCA1-C complex [GO:0070533]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; nuclear speck [GO:0016607]; nuclear ubiquitin ligase complex [GO:0000152]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151] kinase binding [GO:0019900]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; ubiquitin-protein transferase activity [GO:0004842] 0.89779 -0.63099 NEVVTPEK 0 0 0 0 0 0 0 0 8.67937 0 0 0 0 0 0 0 0 0 12.1136 0 0 10.938 0 9.15785 0 0 0 Q99729 ROAA_HUMAN Heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) (APOBEC1-binding protein 1) (ABBP-1) HNRNPAB ABBP1 HNRPAB Homo sapiens (Human) "cellular response to amino acid stimulus [GO:0071230]; epithelial to mesenchymal transition [GO:0001837]; mRNA modification [GO:0016556]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; positive regulation of DNA demethylation [GO:1901537]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of gene expression [GO:0010468]; regulation of intracellular mRNA localization [GO:1904580]" cytoplasm [GO:0005737]; dendrite [GO:0030425]; messenger ribonucleoprotein complex [GO:1990124]; mRNA editing complex [GO:0045293]; neuronal ribonucleoprotein granule [GO:0071598]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA polymerase II transcription regulator complex [GO:0090575] mRNA binding [GO:0003729]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; sequence-specific double-stranded DNA binding [GO:1990837] 0.9194 -0.90853 EVYQQQQYGSGGR 0 0 0 0 0 0 0 14.5661 0 9.03683 0 9.02616 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q99733 NP1L4_HUMAN Nucleosome assembly protein 1-like 4 (Nucleosome assembly protein 2) (NAP-2) NAP1L4 NAP2 Homo sapiens (Human) nucleosome assembly [GO:0006334] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleus [GO:0005634] chromatin binding [GO:0003682]; histone binding [GO:0042393]; nucleosome binding [GO:0031491]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082] 0.58957 0.45905 EFITGDVEPTDAESEWHSENEEEEK 0 0 0 0 0 0 0 10.7102 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q99741 CDC6_HUMAN Cell division control protein 6 homolog (CDC6-related protein) (Cdc18-related protein) (HsCdc18) (p62(cdc6)) (HsCDC6) CDC6 CDC18L Homo sapiens (Human) cell division [GO:0051301]; cellular response to angiotensin [GO:1904385]; cellular response to vasopressin [GO:1904117]; DNA replication checkpoint signaling [GO:0000076]; DNA replication initiation [GO:0006270]; mitotic DNA replication checkpoint signaling [GO:0033314]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; positive regulation of chromosome segregation [GO:0051984]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokinesis [GO:0032467]; positive regulation of fibroblast proliferation [GO:0048146]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; traversing start control point of mitotic cell cycle [GO:0007089] cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle midzone [GO:0051233]; spindle pole [GO:0000922] ATP binding [GO:0005524]; kinase binding [GO:0019900]; nucleotide binding [GO:0000166] 0.94006 -1.3265 ENGPPHSHTLKGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.72741 Q99758 ABCA3_HUMAN Phospholipid-transporting ATPase ABCA3 (EC 7.6.2.1) (ABC-C transporter) (ATP-binding cassette sub-family A member 3) (ATP-binding cassette transporter 3) (ATP-binding cassette 3) (Xenobiotic-transporting ATPase ABCA3) (EC 7.6.2.2) [Cleaved into: 150 Kda mature form] ABCA3 ABC3 Homo sapiens (Human) lipid transport [GO:0006869]; lung development [GO:0030324]; organelle assembly [GO:0070925]; phosphatidylcholine metabolic process [GO:0046470]; phosphatidylglycerol metabolic process [GO:0046471]; phospholipid homeostasis [GO:0055091]; phospholipid transport [GO:0015914]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of phospholipid efflux [GO:1902995]; positive regulation of phospholipid transport [GO:2001140]; positive regulation of protein homooligomerization [GO:0032464]; protein metabolic process [GO:0019538]; regulation of lipid biosynthetic process [GO:0046890]; regulation of phosphatidylcholine metabolic process [GO:0150172]; response to glucocorticoid [GO:0051384]; response to xenobiotic stimulus [GO:0009410]; surfactant homeostasis [GO:0043129]; xenobiotic export from cell [GO:0046618]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport [GO:0042908] alveolar lamellar body [GO:0097208]; alveolar lamellar body membrane [GO:0097233]; cytoplasmic vesicle membrane [GO:0030659]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lamellar body [GO:0042599]; lamellar body membrane [GO:0097232]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; multivesicular body membrane [GO:0032585]; plasma membrane [GO:0005886] ABC-type xenobiotic transporter activity [GO:0008559]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]; lipid transporter activity [GO:0005319]; phosphatidylcholine flippase activity [GO:0140345]; phosphatidylcholine transfer activity [GO:0120019] 0.97012 -3.2266 DQFNEGRK 8.93981 9.12197 0 0 0 0 8.75992 0 10.324 0 0 0 0 0 0 0 0 0 0 9.92116 0 0 9.66688 9.46314 0 0 0 Q99766 ATP5S_HUMAN "ATP synthase subunit s, mitochondrial (ATP synthase-coupling factor B) (FB) (Distal membrane arm assembly complex 2-like protein) (Mitochondrial ATP synthase regulatory component factor B)" DMAC2L ATP5S ATPW Homo sapiens (Human) ATP biosynthetic process [GO:0006754]; proton transmembrane transport [GO:1902600] "cytoplasm [GO:0005737]; mitochondrial inner membrane [GO:0005743]; proton-transporting ATP synthase complex, coupling factor F(o) [GO:0045263]" metal ion binding [GO:0046872]; proton transmembrane transporter activity [GO:0015078] 0.81091 0.22467 ISQQLCGVKKLPWSCDSR 0 0 10.6928 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q99767 APBA2_HUMAN Amyloid-beta A4 precursor protein-binding family A member 2 (Adapter protein X11beta) (Neuron-specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) APBA2 MINT2 X11L Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; in utero embryonic development [GO:0001701]; locomotory behavior [GO:0007626]; multicellular organism growth [GO:0035264]; nervous system development [GO:0007399]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein transport [GO:0015031]; regulation of gene expression [GO:0010468] cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; Schaffer collateral - CA1 synapse [GO:0098685] amyloid-beta binding [GO:0001540]; identical protein binding [GO:0042802] 0.8022 0.23782 SLNLLPEAK 0 0 0 0 0 0 0 13.2447 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q99784 NOE1_HUMAN Noelin (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1) OLFM1 NOE1 NOEL1 Homo sapiens (Human) atrioventricular valve formation [GO:0003190]; cardiac epithelial to mesenchymal transition [GO:0060317]; negative regulation of gene expression [GO:0010629]; nervous system development [GO:0007399]; neuronal signal transduction [GO:0023041]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of gene expression [GO:0010628]; regulation of axon extension [GO:0030516]; signal transduction [GO:0007165] axon [GO:0030424]; axonal growth cone [GO:0044295]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; synapse [GO:0045202] 0.84149 0.18212 FGSWMTDPLAPEGDNR 10.4289 10.3657 0 10.8434 10.9361 0 10.2199 0 9.91054 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q99797 MIPEP_HUMAN Mitochondrial intermediate peptidase (MIP) (EC 3.4.24.59) MIPEP MIP Homo sapiens (Human) peptide metabolic process [GO:0006518]; protein processing involved in protein targeting to mitochondrion [GO:0006627] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222] 0.91467 -0.82816 AAGERYR 0 0 0 0 0 0 11.041 0 0 0 0 11.9407 0 0 10.3565 0 0 8.97298 0 0 8.29425 7.94544 0 9.91616 0 10.934 0 Q99798 ACON_HUMAN "Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase)" ACO2 Homo sapiens (Human) citrate metabolic process [GO:0006101]; generation of precursor metabolites and energy [GO:0006091]; isocitrate metabolic process [GO:0006102]; liver development [GO:0001889]; response to isolation stress [GO:0035900]; tricarboxylic acid cycle [GO:0006099] cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] "3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; citrate dehydratase activity [GO:0047780]; iron ion binding [GO:0005506]" 0 21.263 DGYAQILR 0 0 0 0 0 0 10.587 10.9006 11.1456 10.9446 0 10.4539 0 0 9.78347 0 0 10.4417 10.097 10.3159 0 10.3581 9.3614 10.469 11.3851 10.9051 10.9278 Q99807 COQ7_HUMAN "5-demethoxyubiquinone hydroxylase, mitochondrial (DMQ hydroxylase) (EC 1.14.99.60) (Timing protein clk-1 homolog) (Ubiquinone biosynthesis monooxygenase COQ7)" COQ7 Homo sapiens (Human) determination of adult lifespan [GO:0008340]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; regulation of reactive oxygen species metabolic process [GO:2000377]; ubiquinone biosynthetic process [GO:0006744] chromosome [GO:0005694]; extrinsic component of mitochondrial inner membrane [GO:0031314]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; ubiquinone biosynthesis complex [GO:0110142] "3-demethoxyubiquinol 3-hydroxylase activity [GO:0008682]; chromatin binding [GO:0003682]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]" 0.95958 -1.7185 SLSAYGRR 0 0 0 0 0 0 0 0 0 12.1239 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q99814 EPAS1_HUMAN Endothelial PAS domain-containing protein 1 (EPAS-1) (Basic-helix-loop-helix-PAS protein MOP2) (Class E basic helix-loop-helix protein 73) (bHLHe73) (HIF-1-alpha-like factor) (HLF) (Hypoxia-inducible factor 2-alpha) (HIF-2-alpha) (HIF2-alpha) (Member of PAS protein 2) (PAS domain-containing protein 2) EPAS1 BHLHE73 HIF2A MOP2 PASD2 Homo sapiens (Human) angiogenesis [GO:0001525]; blood vessel remodeling [GO:0001974]; cellular response to hypoxia [GO:0071456]; embryonic placenta development [GO:0001892]; epithelial cell maturation [GO:0002070]; erythrocyte differentiation [GO:0030218]; lung development [GO:0030324]; mitochondrion organization [GO:0007005]; mRNA transcription by RNA polymerase II [GO:0042789]; multicellular organismal-level iron ion homeostasis [GO:0060586]; myoblast fate commitment [GO:0048625]; norepinephrine metabolic process [GO:0042415]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of heart rate [GO:0002027]; regulation of protein neddylation [GO:2000434]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; surfactant homeostasis [GO:0043129]; visual perception [GO:0007601] chromatin [GO:0000785]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; transcription regulator complex [GO:0005667] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription coactivator binding [GO:0001223]" 0.96927 -6.2559 DFFMRMK 10.8737 8.62655 0 0 0 0 0 0 0 12.9739 0 0 0 0 0 0 0 0 0 0 0 0 0 9.05742 0 0 0 Q99828 CIB1_HUMAN Calcium and integrin-binding protein 1 (CIB) (Calcium- and integrin-binding protein) (CIBP) (Calmyrin) (DNA-PKcs-interacting protein) (Kinase-interacting protein) (KIP) (SNK-interacting protein 2-28) (SIP2-28) CIB1 CIB KIP PRKDCIP Homo sapiens (Human) angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; cell division [GO:0051301]; cellular response to growth factor stimulus [GO:0071363]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to tumor necrosis factor [GO:0071356]; cytoplasmic microtubule organization [GO:0031122]; DNA damage response [GO:0006974]; double-strand break repair [GO:0006302]; endomitotic cell cycle [GO:0007113]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; platelet formation [GO:0030220]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of male germ cell proliferation [GO:2000256]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of cell division [GO:0051302]; regulation of cell population proliferation [GO:0042127]; response to ischemia [GO:0002931]; spermatid development [GO:0007286]; thrombopoietin-mediated signaling pathway [GO:0038163] apical plasma membrane [GO:0016324]; axon [GO:0030424]; cell periphery [GO:0071944]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; filopodium tip [GO:0032433]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; vesicle [GO:0031982] calcium ion binding [GO:0005509]; calcium-dependent protein kinase inhibitor activity [GO:0008427]; magnesium ion binding [GO:0000287]; protein serine/threonine kinase inhibitor activity [GO:0030291]; protein-membrane adaptor activity [GO:0043495]; small GTPase binding [GO:0031267]; transmembrane transporter binding [GO:0044325] 0.96173 -2.5603 LSASEMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.57939 8.82477 8.6643 8.70179 0 0 0 0 0 Q99832 TCPH_HUMAN "T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]" CCT7 CCTH NIP7-1 Homo sapiens (Human) binding of sperm to zona pellucida [GO:0007339]; chaperone-mediated protein folding [GO:0061077]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of protein localization to Cajal body [GO:1904871]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; toxin transport [GO:1901998] cell body [GO:0044297]; chaperonin-containing T-complex [GO:0005832]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein folding chaperone [GO:0140662]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082] 0 6.4712 ALEIIPR 8.67285 0 0 0 0 0 10.0739 10.6692 10.7819 10.29 10.2938 14.095 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q99835 SMO_HUMAN Protein smoothened (Protein Gx) SMO SMOH Homo sapiens (Human) alpha-tubulin acetylation [GO:0071929]; anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; atrial septum morphogenesis [GO:0060413]; cell fate specification [GO:0001708]; cellular response to cholesterol [GO:0071397]; central nervous system development [GO:0007417]; central nervous system neuron differentiation [GO:0021953]; cerebellar cortex morphogenesis [GO:0021696]; cerebral cortex development [GO:0021987]; commissural neuron axon guidance [GO:0071679]; contact inhibition [GO:0060242]; dentate gyrus development [GO:0021542]; determination of left/right asymmetry in lateral mesoderm [GO:0003140]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral neural tube patterning [GO:0021904]; epithelial cell proliferation [GO:0050673]; epithelial-mesenchymal cell signaling [GO:0060684]; forebrain morphogenesis [GO:0048853]; gene expression [GO:0010467]; hair follicle morphogenesis [GO:0031069]; heart looping [GO:0001947]; homeostasis of number of cells within a tissue [GO:0048873]; in utero embryonic development [GO:0001701]; left/right axis specification [GO:0070986]; mammary gland epithelial cell differentiation [GO:0060644]; mesenchymal to epithelial transition involved in metanephric renal vesicle formation [GO:0072285]; midgut development [GO:0007494]; multicellular organism growth [GO:0035264]; myoblast migration [GO:0051451]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA binding [GO:0043392]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of gene expression [GO:0010629]; negative regulation of hair follicle development [GO:0051799]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural crest cell migration [GO:0001755]; neuroblast proliferation [GO:0007405]; odontogenesis of dentin-containing tooth [GO:0042475]; osteoblast differentiation [GO:0001649]; pancreas morphogenesis [GO:0061113]; pattern specification process [GO:0007389]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of gene expression [GO:0010628]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of organ growth [GO:0046622]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein import into nucleus [GO:0006606]; protein stabilization [GO:0050821]; regulation of heart morphogenesis [GO:2000826]; regulation of somatic stem cell population maintenance [GO:1904672]; skeletal muscle fiber development [GO:0048741]; smooth muscle tissue development [GO:0048745]; smoothened signaling pathway [GO:0007224]; smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation [GO:0021938]; smoothened signaling pathway involved in ventral spinal cord patterning [GO:0021910]; somite development [GO:0061053]; thalamus development [GO:0021794]; type B pancreatic cell development [GO:0003323]; vasculogenesis [GO:0001570]; ventral midline determination [GO:0007371] 9+0 non-motile cilium [GO:0097731]; centriole [GO:0005814]; ciliary membrane [GO:0060170]; ciliary tip [GO:0097542]; cilium [GO:0005929]; dendrite [GO:0030425]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; patched binding [GO:0005113] 0.16189 0.9991 GVMTLFSIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.8743 0 0 0 0 0 10.2018 0 0 Q99856 ARI3A_HUMAN AT-rich interactive domain-containing protein 3A (ARID domain-containing protein 3A) (B-cell regulator of IgH transcription) (Bright) (Dead ringer-like protein 1) (E2F-binding protein 1) ARID3A DRIL1 DRIL3 DRX E2FBP1 Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] cytosol [GO:0005829]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; transcription coregulator activity [GO:0003712] 0.4185 0.67908 LESAEPPEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8853 0 Q99878 H2A1J_HUMAN Histone H2A type 1-J (Histone H2A/e) H2AC14 H2AFE HIST1H2AJ Homo sapiens (Human) extracellular exosome [GO:0070062]; nucleosome [GO:0000786]; nucleus [GO:0005634] DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; structural constituent of chromatin [GO:0030527] 0 99.26 AGLQFPVGR 12.5645 12.3937 12.4235 9.03433 9.04565 10.1353 12.5021 12.6004 12.399 12.7884 12.7411 12.6035 8.99464 9.5883 10.6578 10.6311 10.1556 8.97229 10.8293 10.7789 11.0855 11.7293 10.0778 11.7884 11.8705 13.4592 10.9201 Q99879 H2B1M_HUMAN Histone H2B type 1-M (Histone H2B.e) (H2B/e) H2BC14 H2BFE HIST1H2BM Homo sapiens (Human) nucleosome assembly [GO:0006334] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634] DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; structural constituent of chromatin [GO:0030527] 0.90601 -0.72592 AMGIMNSFVNDIFER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.08212 0 0 0 0 0 0 0 0 0 0 0 0 Q99880 H2B1L_HUMAN Histone H2B type 1-L (Histone H2B.c) (H2B/c) H2BC13 H2BFC HIST1H2BL Homo sapiens (Human) nucleosome assembly [GO:0006334] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634] DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; structural constituent of chromatin [GO:0030527] 0.95357 -1.5253 AMGIMNSFVNDIFER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3023 0 0 0 0 0 0 0 Q99895 CTRC_HUMAN Chymotrypsin-C (EC 3.4.21.2) (Caldecrin) CTRC CLCR Homo sapiens (Human) intracellular calcium ion homeostasis [GO:0006874]; proteolysis [GO:0006508] peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252] 0.96943 -4.908 IDWWGFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1493 0 9.98527 Q99909 SSX3_HUMAN Protein SSX3 (Cancer/testis antigen 5.3) (CT5.3) SSX3 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] 0.95176 -1.4396 GEHAWTHRLRER 0 11.4185 0 0 0 0 0 0 0 0 0 0 10.5504 0 0 0 10.7086 0 0 0 0 0 0 0 0 0 0 Q99928 GBRG3_HUMAN Gamma-aminobutyric acid receptor subunit gamma-3 (GABA(A) receptor subunit gamma-3) GABRG3 Homo sapiens (Human) "chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; nervous system process [GO:0050877]; regulation of postsynaptic membrane potential [GO:0060078]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165]; synaptic transmission, GABAergic [GO:0051932]" chloride channel complex [GO:0034707]; dendrite membrane [GO:0032590]; GABA-A receptor complex [GO:1902711]; GABA-ergic synapse [GO:0098982]; microtubule cytoskeleton [GO:0015630]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202] GABA-A receptor activity [GO:0004890]; GABA-gated chloride ion channel activity [GO:0022851]; inhibitory extracellular ligand-gated monoatomic ion channel activity [GO:0005237]; transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315] 0.95827 -1.6774 MAPKLLLLLCLFSGLHAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.36394 0 0 0 9.37584 0 0 0 0 0 0 Q99933 BAG1_HUMAN BAG family molecular chaperone regulator 1 (BAG-1) (Bcl-2-associated athanogene 1) BAG1 HAP Homo sapiens (Human) apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; protein stabilization [GO:0050821] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] adenyl-nucleotide exchange factor activity [GO:0000774]; protein-folding chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625] 0.96581 -2.3026 GAAAGAR 0 0 0 7.81449 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.388 0 0 0 Q99943 PLCA_HUMAN 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 1) (1-AGP acyltransferase 1) (1-AGPAT 1) (Lysophosphatidic acid acyltransferase alpha) (LPAAT-alpha) (Protein G15) AGPAT1 G15 Homo sapiens (Human) CDP-diacylglycerol biosynthetic process [GO:0016024]; phosphatidic acid biosynthetic process [GO:0006654]; phospholipid metabolic process [GO:0006644]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine-mediated signaling pathway [GO:0001961] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] 1-acylglycerol-3-phosphate O-acyltransferase activity [GO:0003841] 0.65223 0.39575 GGGDYLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.81317 0 0 8.88795 8.82257 0 0 0 Q99952 PTN18_HUMAN Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase) PTPN18 BDP1 Homo sapiens (Human) blastocyst formation [GO:0001825]; negative regulation of ERBB signaling pathway [GO:1901185]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; protein tyrosine phosphatase activity [GO:0004725] 0.92429 -0.99098 EIENGRK 0 9.78387 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.72586 Q99958 FOXC2_HUMAN Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14) FOXC2 FKHL14 MFH1 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; apoptotic process involved in outflow tract morphogenesis [GO:0003275]; artery morphogenesis [GO:0048844]; blood vessel diameter maintenance [GO:0097746]; blood vessel remodeling [GO:0001974]; branching involved in blood vessel morphogenesis [GO:0001569]; camera-type eye development [GO:0043010]; cardiac muscle cell proliferation [GO:0060038]; cell differentiation [GO:0030154]; collagen fibril organization [GO:0030199]; embryonic heart tube development [GO:0035050]; embryonic viscerocranium morphogenesis [GO:0048703]; glomerular endothelium development [GO:0072011]; glomerular mesangial cell development [GO:0072144]; heart development [GO:0007507]; insulin receptor signaling pathway [GO:0008286]; lymphangiogenesis [GO:0001946]; mesoderm development [GO:0007498]; metanephros development [GO:0001656]; negative regulation of apoptotic process involved in outflow tract morphogenesis [GO:1902257]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural crest cell development [GO:0014032]; Notch signaling pathway [GO:0007219]; ossification [GO:0001503]; paraxial mesodermal cell fate commitment [GO:0048343]; podocyte differentiation [GO:0072112]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular wound healing [GO:0035470]; regulation of organ growth [GO:0046620]; regulation of transcription by RNA polymerase II [GO:0006357]; response to hormone [GO:0009725]; somitogenesis [GO:0001756]; ureteric bud development [GO:0001657]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; ventricular cardiac muscle tissue morphogenesis [GO:0055010] chromatin [GO:0000785]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "chromatin DNA binding [GO:0031490]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]" 0.23662 0.85025 KDVSKEK 0 0 0 0 0 0 0 0 0 0 0 0 11.1377 11.0902 0 0 0 0 0 0 0 0 0 0 0 0 0 Q99959 PKP2_HUMAN Plakophilin-2 PKP2 Homo sapiens (Human) bundle of His cell-Purkinje myocyte adhesion involved in cell communication [GO:0086073]; cardiac muscle cell action potential involved in contraction [GO:0086002]; cell communication by electrical coupling involved in cardiac conduction [GO:0086064]; cell-cell adhesion [GO:0098609]; cell-cell junction assembly [GO:0007043]; cell-cell signaling involved in cardiac conduction [GO:0086019]; desmosome assembly [GO:0002159]; desmosome organization [GO:0002934]; heart development [GO:0007507]; intermediate filament bundle assembly [GO:0045110]; maintenance of animal organ identity [GO:0048496]; positive regulation of sodium ion transport [GO:0010765]; protein localization to plasma membrane [GO:0072659]; regulation of cell-substrate adhesion [GO:0010810]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; ventricular cardiac muscle cell action potential [GO:0086005]; ventricular cardiac muscle tissue morphogenesis [GO:0055010] adherens junction [GO:0005912]; cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; desmosome [GO:0030057]; intercalated disc [GO:0014704]; intermediate filament [GO:0005882]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] alpha-catenin binding [GO:0045294]; cadherin binding [GO:0045296]; cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication [GO:0086083]; intermediate filament binding [GO:0019215]; molecular adaptor activity [GO:0060090]; protein kinase C binding [GO:0005080]; sodium channel regulator activity [GO:0017080]; transmembrane transporter binding [GO:0044325] 0.87774 -0.01401 EQYQDVPMPEEKSNPK 0 0 0 0 9.67055 11.2459 0 9.96482 0 0 9.78851 0 0 0 0 0 0 0 0 11.718 0 0 0 0 0 0 0 Q99961 SH3G1_HUMAN Endophilin-A2 (EEN fusion partner of MLL) (Endophilin-2) (Extra eleven-nineteen leukemia fusion gene protein) (EEN) (SH3 domain protein 2B) (SH3 domain-containing GRB2-like protein 1) SH3GL1 CNSA1 SH3D2B Homo sapiens (Human) central nervous system development [GO:0007417]; signal transduction [GO:0007165]; synaptic vesicle uncoating [GO:0016191] anchoring junction [GO:0070161]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; glutamatergic synapse [GO:0098978]; podosome [GO:0002102]; presynapse [GO:0098793] cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; lipid binding [GO:0008289] 0.88305 -0.27512 RMREASSRPK 0 8.51688 0 0 0 0 9.15168 9.16372 0 0 0 0 0 0 0 0 0 0 9.07644 0 0 0 9.84057 0 0 10.1134 0 Q99963 SH3G3_HUMAN Endophilin-A3 (EEN-B2) (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3) SH3GL3 CNSA3 SH3D2C Homo sapiens (Human) central nervous system development [GO:0007417]; negative regulation of clathrin-dependent endocytosis [GO:1900186]; positive regulation of neuron differentiation [GO:0045666]; signal transduction [GO:0007165]; synaptic vesicle uncoating [GO:0016191] "acrosomal vesicle [GO:0001669]; early endosome membrane [GO:0031901]; glutamatergic synapse [GO:0098978]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic endosome [GO:0098845]; presynapse [GO:0098793]" identical protein binding [GO:0042802]; lipid binding [GO:0008289] 0.95473 -1.5201 QAVEKFEESK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.56744 0 0 0 0 0 0 0 0 Q99972 MYOC_HUMAN "Myocilin (Myocilin 55 kDa subunit) (Trabecular meshwork-induced glucocorticoid response protein) [Cleaved into: Myocilin, N-terminal fragment (Myocilin 20 kDa N-terminal fragment); Myocilin, C-terminal fragment (Myocilin 35 kDa N-terminal fragment)]" MYOC GLC1A TIGR Homo sapiens (Human) bone development [GO:0060348]; clustering of voltage-gated sodium channels [GO:0045162]; ERBB2-ERBB3 signaling pathway [GO:0038133]; myelination in peripheral nervous system [GO:0022011]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; neuron projection development [GO:0031175]; non-canonical Wnt signaling pathway via JNK cascade [GO:0038031]; osteoblast differentiation [GO:0001649]; positive regulation of cell migration [GO:0030335]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of MAPK cascade [GO:0043408]; signal transduction [GO:0007165]; skeletal muscle hypertrophy [GO:0014734] cilium [GO:0005929]; collagen-containing extracellular matrix [GO:0062023]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; node of Ranvier [GO:0033268]; rough endoplasmic reticulum [GO:0005791] fibronectin binding [GO:0001968]; frizzled binding [GO:0005109]; metal ion binding [GO:0046872]; myosin light chain binding [GO:0032027]; receptor tyrosine kinase binding [GO:0030971] 0.84733 0.1705 ESPSGYLR 0 0 0 0 0 0 0 0 0 0 10.58 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q99973 TEP1_HUMAN Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog) TEP1 TLP1 TP1 Homo sapiens (Human) telomere maintenance via recombination [GO:0000722] "chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; nuclear matrix [GO:0016363]; ribonucleoprotein complex [GO:1990904]; telomerase holoenzyme complex [GO:0005697]" ATP binding [GO:0005524]; enzyme binding [GO:0019899]; p53 binding [GO:0002039]; RNA binding [GO:0003723]; telomerase activity [GO:0003720]; telomerase RNA binding [GO:0070034] 0.96006 -1.9011 DRSLLCWDVRTPK 0 0 0 0 0 9.42461 0 0 0 0 0 10.4193 0 0 0 0 9.27247 0 0 0 0 9.67004 0 0 0 0 0 Q99985 SEM3C_HUMAN Semaphorin-3C (Semaphorin-E) (Sema E) SEMA3C SEMAE Homo sapiens (Human) axon guidance [GO:0007411]; blood vessel remodeling [GO:0001974]; cardiac endothelial to mesenchymal transition [GO:0140074]; cardiac right ventricle morphogenesis [GO:0003215]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; immune response [GO:0006955]; limb bud formation [GO:0060174]; negative chemotaxis [GO:0050919]; negative regulation of axon extension involved in axon guidance [GO:0048843]; neural crest cell migration [GO:0001755]; neural tube development [GO:0021915]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis [GO:1905312]; positive regulation of cell migration [GO:0030335]; post-embryonic development [GO:0009791]; pulmonary myocardium development [GO:0003350]; response to xenobiotic stimulus [GO:0009410]; semaphorin-plexin signaling pathway [GO:0071526]; somitogenesis [GO:0001756] extracellular exosome [GO:0070062] chemorepellent activity [GO:0045499]; semaphorin receptor binding [GO:0030215] 0.96823 -3.6317 DIMGAFSHSEMQMINQYCK 0 11.1443 0 0 0 0 13.1274 0 0 11.719 8.89785 0 0 9.66899 0 0 0 0 0 0 0 0 0 0 0 0 0 Q99986 VRK1_HUMAN Serine/threonine-protein kinase VRK1 (EC 2.7.11.1) (Vaccinia-related kinase 1) VRK1 Homo sapiens (Human) cell division [GO:0051301]; DNA damage response [GO:0006974]; Golgi disassembly [GO:0090166]; mitotic nuclear membrane disassembly [GO:0007077]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of protein localization to chromatin [GO:0120187]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] cytosol [GO:0005829]; Golgi stack [GO:0005795]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; histone binding [GO:0042393]; histone H3S10 kinase activity [GO:0035175]; histone H3T3 kinase activity [GO:0072354]; molecular function activator activity [GO:0140677]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96885 -3.5994 KTVLQLSLR 12.4362 0 0 0 0 0 0 0 0 0 0 0 0 9.24194 0 0 0 0 0 0 0 0 0 0 0 0 0 Q99996 AKAP9_HUMAN A-kinase anchor protein 9 (AKAP-9) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (A-kinase anchor protein 450 kDa) (AKAP 450) (AKAP 120-like protein) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP) (Protein hyperion) (Protein kinase A-anchoring protein 9) (PRKA9) (Protein yotiao) AKAP9 AKAP350 AKAP450 KIAA0803 Homo sapiens (Human) cellular response to cAMP [GO:0071320]; chemical synaptic transmission [GO:0007268]; maintenance of centrosome location [GO:0051661]; microtubule nucleation [GO:0007020]; negative regulation of adenylate cyclase activity [GO:0007194]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; protein-containing complex localization [GO:0031503]; regulation of cardiac muscle cell action potential involved in regulation of contraction [GO:0098909]; regulation of Golgi organization [GO:1903358]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of membrane repolarization [GO:0060306]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to electrical stimulus [GO:0051602]; signal transduction [GO:0007165] centrosome [GO:0005813]; cis-Golgi network [GO:0005801]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic branch [GO:0044307]; extrinsic component of postsynaptic density membrane [GO:0099147]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi stack [GO:0005795]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; potassium channel complex [GO:0034705]; synaptic membrane [GO:0097060]; voltage-gated potassium channel complex [GO:0008076] DNA binding [GO:0003677]; molecular adaptor activity [GO:0060090]; potassium channel regulator activity [GO:0015459]; protein kinase A regulatory subunit binding [GO:0034237]; signaling receptor binding [GO:0005102]; transmembrane transporter binding [GO:0044325] 0.96905 -6.755 DIQERNEEIEK 10.0392 0 9.99251 11.5508 0 9.45092 10.2058 9.99831 9.07625 0 0 9.97699 8.39476 0 0 9.92785 0 0 0 0 9.41614 9.88527 9.50692 10.9192 11.2896 8.83058 10.9457 Q9BPU6 DPYL5_HUMAN Dihydropyrimidinase-related protein 5 (DRP-5) (CRMP3-associated molecule) (CRAM) (Collapsin response mediator protein 5) (CRMP-5) (UNC33-like phosphoprotein 6) (ULIP-6) DPYSL5 CRMP5 ULIP6 Homo sapiens (Human) axon guidance [GO:0007411]; negative regulation of dendrite morphogenesis [GO:0050774]; nervous system development [GO:0007399]; signal transduction [GO:0007165] cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; protein-containing complex [GO:0032991] "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [GO:0016812]" 0.78597 0.24942 DIGAIAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.49729 0 Q9BPV8 P2Y13_HUMAN P2Y purinoceptor 13 (P2Y13) (G-protein coupled receptor 86) (G-protein coupled receptor 94) P2RY13 GPR86 GPR94 FKSG77 Homo sapiens (Human) cellular response to organic cyclic compound [GO:0071407]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of adenylate cyclase activity [GO:0007194] endoplasmic reticulum [GO:0005783]; plasma membrane [GO:0005886] G protein-coupled purinergic nucleotide receptor activity [GO:0045028] 0.84998 0.11087 VTLEAMNTTVMQGFNR 0 0 0 9.0778 9.24512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BPW5 RSLBB_HUMAN Ras-like protein family member 11B (EC 3.6.5.2) RASL11B Homo sapiens (Human) negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512] G protein activity [GO:0003925]; GTP binding [GO:0005525]; transforming growth factor beta receptor binding [GO:0005160] 0.96735 -2.8022 EVSHKQQPSSTPEK 0 9.47204 0 0 9.16862 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BPX3 CND3_HUMAN Condensin complex subunit 3 (Chromosome-associated protein G) (Condensin subunit CAP-G) (hCAP-G) (Melanoma antigen NY-MEL-3) (Non-SMC condensin I complex subunit G) (XCAP-G homolog) NCAPG CAPG NYMEL3 Homo sapiens (Human) cell division [GO:0051301]; mitotic chromosome condensation [GO:0007076]; positive regulation of chromosome condensation [GO:1905821]; positive regulation of chromosome segregation [GO:0051984]; positive regulation of chromosome separation [GO:1905820] "condensed chromosome [GO:0000793]; condensed chromosome, centromeric region [GO:0000779]; condensed nuclear chromosome [GO:0000794]; condensin complex [GO:0000796]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]" 0.92292 -1.1587 GAERRLLSIK 14.3222 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.47356 0 0 0 0 0 Q9BPX6 MICU1_HUMAN "Calcium uptake protein 1, mitochondrial (Atopy-related autoantigen CALC) (ara CALC) (Calcium-binding atopy-related autoantigen 1) (allergen Hom s 4)" MICU1 CALC CBARA1 Homo sapiens (Human) calcium import into the mitochondrion [GO:0036444]; calcium ion import [GO:0070509]; defense response [GO:0006952]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transmembrane transport [GO:0006851]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; protein homooligomerization [GO:0051260]; regulation of cellular hyperosmotic salinity response [GO:1900069] calcium channel complex [GO:0034704]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; uniplex complex [GO:1990246] calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982] 0.91434 -0.78469 LMQAMWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.68909 0 0 0 10.2997 0 0 0 0 Q9BPY3 F118B_HUMAN Protein FAM118B FAM118B Homo sapiens (Human) Cajal body [GO:0015030] identical protein binding [GO:0042802] 0.91503 -0.81077 RGDVDEFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1524 0 0 0 0 0 0 Q9BPZ7 SIN1_HUMAN Target of rapamycin complex 2 subunit MAPKAP1 (TORC2 subunit MAPKAP1) (Mitogen-activated protein kinase 2-associated protein 1) (Stress-activated map kinase-interacting protein 1) (SAPK-interacting protein 1) (mSIN1) MAPKAP1 MIP1 SIN1 Homo sapiens (Human) cellular response to nutrient levels [GO:0031669]; cytoskeleton organization [GO:0007010]; negative regulation of apoptotic process [GO:0043066]; negative regulation of Ras protein signal transduction [GO:0046580]; phosphorylation [GO:0016310]; positive regulation of cell growth [GO:0030307]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; regulation of cellular response to oxidative stress [GO:1900407]; substantia nigra development [GO:0021762]; TORC2 signaling [GO:0038203] cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; TORC2 complex [GO:0031932] "molecular adaptor activity [GO:0060090]; phosphatidic acid binding [GO:0070300]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein kinase binding [GO:0019901]; small GTPase binding [GO:0031267]" 0.95379 -1.5224 ADYFAQKQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.22932 0 0 Q9BQ04 RBM4B_HUMAN RNA-binding protein 4B (RNA-binding motif protein 30) (RNA-binding motif protein 4B) (RNA-binding protein 30) RBM4B RBM30 Homo sapiens (Human) "circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of gene expression [GO:0010628]; regulation of translation [GO:0006417]" cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991] RNA binding [GO:0003723]; zinc ion binding [GO:0008270] 0.61236 0.42079 LFIGNLPR 0 0 0 0 0 0 0 0 9.06437 0 0 0 0 0 0 0 0 0 0 0 0 0 8.80416 0 0 0 0 Q9BQ16 TICN3_HUMAN "Testican-3 (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3)" SPOCK3 TICN3 UNQ409/PRO771 Homo sapiens (Human) negative regulation of cell motility [GO:2000146]; negative regulation of endopeptidase activity [GO:0010951]; peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan [GO:0019800] extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] calcium ion binding [GO:0005509]; glycosaminoglycan binding [GO:0005539]; metalloendopeptidase inhibitor activity [GO:0008191] 0.96838 -3.3508 LTHRMKEAGVDHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.4463 0 0 0 0 0 0 0 10.1439 0 0 Q9BQ31 KCNS3_HUMAN Potassium voltage-gated channel subfamily S member 3 (Delayed-rectifier K(+) channel alpha subunit 3) (Voltage-gated potassium channel subunit Kv9.3) KCNS3 Homo sapiens (Human) potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of monoatomic ion transmembrane transport [GO:0034765] cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076] delayed rectifier potassium channel activity [GO:0005251]; potassium channel regulator activity [GO:0015459]; voltage-gated potassium channel activity [GO:0005249] 0.87163 0.027098 DIDVDQCSEDAPEK 0 0 0 0 0 0 0 0 9.52728 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BQ39 DDX50_HUMAN ATP-dependent RNA helicase DDX50 (EC 3.6.4.13) (DEAD box protein 50) (Gu-beta) (Nucleolar protein Gu2) DDX50 Homo sapiens (Human) membrane [GO:0016020]; nucleolus [GO:0005730]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.96463 -2.3809 DLIAQARTGTGK 0 0 0 0 0 0 0 0 0 0 0 10.8786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BQ69 MACD1_HUMAN ADP-ribose glycohydrolase MACROD1 (MACRO domain-containing protein 1) (O-acetyl-ADP-ribose deacetylase MACROD1) (EC 3.1.1.106) (Protein LRP16) ([Protein ADP-ribosylaspartate] hydrolase MACROD1) (EC 3.2.2.-) ([Protein ADP-ribosylglutamate] hydrolase MACROD1) (EC 3.2.2.-) MACROD1 LRP16 Homo sapiens (Human) DNA damage response [GO:0006974]; peptidyl-glutamate ADP-deribosylation [GO:0140291]; protein de-ADP-ribosylation [GO:0051725]; purine nucleoside metabolic process [GO:0042278] nucleoplasm [GO:0005654]; nucleus [GO:0005634] "ADP-ribosylglutamate hydrolase activity [GO:0140293]; deacetylase activity [GO:0019213]; hydrolase activity, acting on glycosyl bonds [GO:0016798]" 0.96951 -3.0417 GLSDKQR 0 0 0 10.099 0 0 0 0 0 0 9.00809 0 0 0 0 0 0 10.1417 0 0 0 0 0 0 0 0 0 Q9BQ70 TCF25_HUMAN Ribosome quality control complex subunit TCF25 (Nuclear localized protein 1) (Transcription factor 25) (TCF-25) TCF25 KIAA1049 NULP1 FKSG26 Homo sapiens (Human) heart development [GO:0007507]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of protein K48-linked ubiquitination [GO:0061945]; rescue of stalled ribosome [GO:0072344] nucleus [GO:0005634]; RQC complex [GO:1990112] DNA binding [GO:0003677]; transcription corepressor activity [GO:0003714] 0.92997 -1.2452 VLYQRAPR 10.3405 8.38016 0 15.4655 15.1969 0 17.1634 0 0 0 8.75649 0 0 8.94743 0 0 0 15.1341 8.09339 0 0 0 0 0 0 0 0 Q9BQ89 F110A_HUMAN Protein FAM110A FAM110A C20orf55 F10 Homo sapiens (Human) mitotic spindle organization [GO:0007052] cell cortex [GO:0005938]; centrosome [GO:0005813]; cytosol [GO:0005829]; nucleus [GO:0005634]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922] 0.91524 -0.81168 GLGVAHLAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.5548 0 0 0 0 0 0 0 0 0 0 Q9BQ95 ECSIT_HUMAN "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (Protein SITPEC)" ECSIT Homo sapiens (Human) innate immune response [GO:0045087]; mitochondrial respiratory chain complex I assembly [GO:0032981]; regulation of oxidoreductase activity [GO:0051341]; regulation of protein complex stability [GO:0061635] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.92021 -1.1434 CVYYHILR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4022 0 0 0 0 0 9.3884 0 0 0 0 0 0 Q9BQA5 HINFP_HUMAN Histone H4 transcription factor (Histone nuclear factor P) (HiNF-P) (MBD2-interacting zinc finger protein) (Methyl-CpG-binding protein 2-interacting zinc finger protein) HINFP MIZF ZNF743 Homo sapiens (Human) anatomical structure development [GO:0048856]; DNA damage checkpoint signaling [GO:0000077]; DNA repair [GO:0006281]; establishment of protein localization [GO:0045184]; G1/S transition of mitotic cell cycle [GO:0000082]; in utero embryonic development [GO:0001701]; myoblast differentiation [GO:0045445]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083] Cajal body [GO:0015030]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; histone binding [GO:0042393]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; transcription cis-regulatory region binding [GO:0000976]" 0.83644 0.18819 HSEDRPFK 0 0 0 0 0 0 9.27726 0 9.5875 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BQB4 SOST_HUMAN Sclerostin SOST UNQ2976/PRO7455/PRO7476 Homo sapiens (Human) BMP signaling pathway [GO:0030509]; canonical Wnt signaling pathway [GO:0060070]; cellular response to parathyroid hormone stimulus [GO:0071374]; localization [GO:0051179]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of Wnt signaling pathway [GO:0030178]; ossification [GO:0001503]; positive regulation of DNA-templated transcription [GO:0045893]; response to mechanical stimulus [GO:0009612] extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; protein-containing complex [GO:0032991] BMP binding [GO:0036122]; carbohydrate binding [GO:0030246]; DNA-binding transcription factor binding [GO:0140297]; heparin binding [GO:0008201]; molecular function inhibitor activity [GO:0140678] 0.96319 -2.159 LVASCKCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3583 0 0 0 0 0 Q9BQE5 APOL2_HUMAN Apolipoprotein L2 (Apolipoprotein L-II) (ApoL-II) APOL2 Homo sapiens (Human) acute-phase response [GO:0006953]; cholesterol metabolic process [GO:0008203]; lipid metabolic process [GO:0006629]; lipid transport [GO:0006869]; lipoprotein metabolic process [GO:0042157]; maternal process involved in female pregnancy [GO:0060135] endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; membrane [GO:0016020] high-density lipoprotein particle binding [GO:0008035]; lipid binding [GO:0008289]; signaling receptor binding [GO:0005102] 0.91466 -0.79606 ELEDHIRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.24871 0 0 0 0 Q9BQE9 BCL7B_HUMAN B-cell CLL/lymphoma 7 protein family member B (allergen Hom s 3) BCL7B Homo sapiens (Human) apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; chromatin remodeling [GO:0006338]; negative regulation of cell differentiation [GO:0045596]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of stem cell population maintenance [GO:1902459]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357]; Wnt signaling pathway [GO:0016055] chromatin [GO:0000785]; GBAF complex [GO:0140288]; SWI/SNF complex [GO:0016514] actin binding [GO:0003779] 0.96131 -2.5603 SNSSAAR 0 0 0 0 0 0 0 0 0 0 9.49514 9.14591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BQF6 SENP7_HUMAN Sentrin-specific protease 7 (EC 3.4.22.-) (SUMO-1-specific protease 2) (Sentrin/SUMO-specific protease SENP7) SENP7 KIAA1707 SSP2 SUSP2 Homo sapiens (Human) antiviral innate immune response [GO:0140374]; protein desumoylation [GO:0016926] cytoplasm [GO:0005737]; nucleus [GO:0005634] SUMO-specific endopeptidase activity [GO:0070139] 0.96717 -2.8252 GASKGCVTITK 0 0 0 0 0 0 0 0 0 9.65812 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BQG0 MBB1A_HUMAN Myb-binding protein 1A MYBBP1A P160 Homo sapiens (Human) cellular response to glucose starvation [GO:0042149]; chromatin remodeling [GO:0006338]; circadian regulation of gene expression [GO:0032922]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; negative regulation of DNA-templated transcription [GO:0045892]; osteoblast differentiation [GO:0001649]; positive regulation of anoikis [GO:2000210]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; regulation of DNA-templated transcription [GO:0006355]; regulation of G1 to G0 transition [GO:1903450]; respiratory electron transport chain [GO:0022904]; ribosome biogenesis [GO:0042254] B-WICH complex [GO:0110016]; cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; NLS-dependent protein nuclear import complex [GO:0042564]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] E-box binding [GO:0070888]; RNA binding [GO:0003723]; sequence-specific DNA binding [GO:0043565]; transcription corepressor activity [GO:0003714] 0.91757 -0.86562 EQLHLVMQGDVIR 10.2753 0 0 10.9971 0 0 10.8057 0 10.8647 0 0 0 0 0 0 9.70974 0 0 0 0 0 0 0 0 0 0 0 Q9BQG2 NUD12_HUMAN NAD-capped RNA hydrolase NUDT12 (DeNADding enzyme NUDT12) (EC 3.6.1.-) (NADH pyrophosphatase NUDT12) (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12) NUDT12 Homo sapiens (Human) circadian regulation of gene expression [GO:0032922]; methylguanosine-cap decapping [GO:0110156]; mRNA catabolic process [GO:0006402]; NAD biosynthesis via nicotinamide riboside salvage pathway [GO:0034356]; NAD catabolic process [GO:0019677]; NAD-cap decapping [GO:0110155]; NADH metabolic process [GO:0006734]; NADP catabolic process [GO:0006742] cytoplasm [GO:0005737]; nucleus [GO:0005634]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777] magnesium ion binding [GO:0000287]; NAD+ diphosphatase activity [GO:0000210]; NADH pyrophosphatase activity [GO:0035529]; phosphodiesterase decapping endonuclease activity [GO:1990174]; RNA NAD-cap (NMN-forming) hydrolase activity [GO:0110153]; zinc ion binding [GO:0008270] 0.95024 -1.3838 DYLAQPEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.05094 0 0 0 0 Q9BQI0 AIF1L_HUMAN Allograft inflammatory factor 1-like (Ionized calcium-binding adapter molecule 2) AIF1L C9orf58 IBA2 UNQ672/PRO1306 Homo sapiens (Human) actin filament bundle assembly [GO:0051017]; ruffle assembly [GO:0097178] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; ruffle membrane [GO:0032587] actin filament binding [GO:0051015]; calcium ion binding [GO:0005509] 0.91696 -0.7671 LAEINREFLCDQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4223 0 0 0 Q9BQI3 E2AK1_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-controlled repressor) (HCR) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (hHRI) (Hemin-sensitive initiation factor 2-alpha kinase) EIF2AK1 HRI KIAA1369 PRO1362 Homo sapiens (Human) acute inflammatory response [GO:0002526]; establishment of localization in cell [GO:0051649]; HRI-mediated signaling [GO:0140468]; integrated stress response signaling [GO:0140467]; macrophage differentiation [GO:0030225]; multicellular organismal-level iron ion homeostasis [GO:0060586]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of hemoglobin biosynthetic process [GO:0046986]; negative regulation of translational initiation by iron [GO:0045993]; phagocytosis [GO:0006909]; protein autophosphorylation [GO:0046777]; protoporphyrinogen IX metabolic process [GO:0046501]; regulation of eIF2 alpha phosphorylation by heme [GO:0010999]; response to iron ion starvation [GO:1990641] cytoplasm [GO:0005737] ATP binding [GO:0005524]; eukaryotic translation initiation factor 2alpha kinase activity [GO:0004694]; heme binding [GO:0020037]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310] 0.92022 -1.1426 GVRDDGK 0 0 0 0 0 0 0 0 0 7.92148 0 0 0 0 0 0 0 0 0 0 0 0 8.48115 8.49005 0 0 0 Q9BQI5 SGIP1_HUMAN SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin-3-interacting protein) SGIP1 Homo sapiens (Human) clathrin-dependent endocytosis [GO:0072583]; energy homeostasis [GO:0097009]; positive regulation of feeding behavior [GO:2000253]; positive regulation of receptor-mediated endocytosis [GO:0048260]; response to dietary excess [GO:0002021] AP-2 adaptor complex [GO:0030122]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886] microtubule binding [GO:0008017]; phospholipid binding [GO:0005543]; SH3 domain binding [GO:0017124] 0.86858 0.069334 FYLTFEGSSR 0 0 0 0 0 0 0 0 0 0 0 8.97281 0 0 0 0 0 0 0 9.06743 0 0 0 0 0 0 0 Q9BQI6 SLF1_HUMAN SMC5-SMC6 complex localization factor protein 1 (Ankyrin repeat domain-containing protein 32) (BRCT domain-containing protein 1) (Smc5/6 localization factor 1) SLF1 ANKRD32 BRCTD1 Homo sapiens (Human) DNA damage response [GO:0006974]; double-strand break repair via homologous recombination [GO:0000724]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of protein-containing complex assembly [GO:0031334]; protein localization to site of double-strand break [GO:1990166]; protein sumoylation [GO:0016925]; regulation of telomere maintenance [GO:0032204] "centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; nuclear inclusion body [GO:0042405]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]; Smc5-Smc6 complex [GO:0030915]" protein-containing complex binding [GO:0044877]; ubiquitin protein ligase binding [GO:0031625] 0.96945 -6.0207 CSSSLKK 0 0 0 0 8.85125 0 0 0 0 12.1549 0 8.81092 0 0 0 8.7495 0 0 0 0 0 10.097 0 0 0 0 9.99986 Q9BQI7 PSD2_HUMAN PH and SEC7 domain-containing protein 2 (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 C) (Exchange factor for ARF6 C) (Pleckstrin homology and SEC7 domain-containing protein 2) PSD2 EFA6C Homo sapiens (Human) regulation of ARF protein signal transduction [GO:0032012] cleavage furrow [GO:0032154]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587] guanyl-nucleotide exchange factor activity [GO:0005085]; phospholipid binding [GO:0005543] 0.89691 -0.67522 DATGPDT 0 0 0 0 0 0 0 0 0 8.25125 0 9.08055 9.55543 8.73738 9.92935 0 0 10.882 9.87049 9.95613 10.0879 10.0308 0 7.85966 9.41863 9.91337 11.0645 Q9BQI9 NRIP2_HUMAN Nuclear receptor-interacting protein 2 NRIP2 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; proteolysis [GO:0006508] cytoplasm [GO:0005737]; nucleus [GO:0005634] aspartic-type endopeptidase activity [GO:0004190] 0.93924 -1.3036 RLKQATQFLHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5152 0 0 0 0 0 0 0 0 9.17078 0 0 0 Q9BQK8 LPIN3_HUMAN Phosphatidate phosphatase LPIN3 (EC 3.1.3.4) (Lipin-3) (Lipin-3-like) LPIN3 LIPN3L Homo sapiens (Human) cellular response to insulin stimulus [GO:0032869]; fatty acid catabolic process [GO:0009062]; positive regulation of transcription by RNA polymerase II [GO:0045944]; triglyceride biosynthetic process [GO:0019432] endoplasmic reticulum membrane [GO:0005789]; nucleus [GO:0005634] phosphatidate phosphatase activity [GO:0008195]; transcription coactivator activity [GO:0003713] 0.0057637 2.3221 AIGMADLTK 12.543 12.5431 12.3244 10.7388 10.851 10.7973 11.8813 11.9972 11.8096 13.7026 13.6387 13.9254 9.99322 9.96867 9.98868 10.6795 10.8011 10.8077 0 0 0 0 0 0 0 0 0 Q9BQM9 CT144_HUMAN Uncharacterized protein C20orf144 (Bcl-2-like protein from testis) (Bclt) C20orf144 Homo sapiens (Human) 0.92415 -1.1734 AALSWPR 0 0 0 0 0 9.30367 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.90412 0 0 Q9BQN1 FA83C_HUMAN Protein FAM83C FAM83C C20orf128 Homo sapiens (Human) epidermal growth factor receptor signaling pathway [GO:0007173] protein kinase binding [GO:0019901] 0.96917 -4.5203 IVEDFDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.46222 0 0 0 0 0 0 0 0 0 0 0 0 Q9BQP7 MGME1_HUMAN Mitochondrial genome maintenance exonuclease 1 (EC 3.1.-.-) MGME1 C20orf72 DDK1 Homo sapiens (Human) mitochondrial DNA repair [GO:0043504]; mitochondrial DNA replication [GO:0006264]; mitochondrial genome maintenance [GO:0000002] mitochondrion [GO:0005739] single-stranded DNA 5'-3' DNA exonuclease activity [GO:0045145]; single-stranded DNA exodeoxyribonuclease activity [GO:0008297] 0.90485 -0.73011 LEEYTEK 0 0 0 0 0 0 0 0 0 0 0 10.907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BQP9 BPIA3_HUMAN "BPI fold-containing family A member 3 (Short palate, lung and nasal epithelium carcinoma-associated protein 3)" BPIFA3 C20orf71 SPLUNC3 Homo sapiens (Human) extracellular region [GO:0005576] lipid binding [GO:0008289] 0.77224 0.27056 MMCPLWR 0 8.76537 0 0 0 0 0 0 0 0 0 0 0 0 10.2037 0 0 0 0 0 0 0 0 0 0 0 0 Q9BQQ3 GORS1_HUMAN Golgi reassembly-stacking protein 1 (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5) (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) GORASP1 GOLPH5 GRASP65 Homo sapiens (Human) establishment of protein localization to plasma membrane [GO:0061951]; Golgi organization [GO:0007030]; negative regulation of dendrite morphogenesis [GO:0050774]; protein N-linked glycosylation [GO:0006487]; protein transport [GO:0015031] cis-Golgi network [GO:0005801]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139] metal ion binding [GO:0046872] 0.77672 0.26358 LEVFNMK 0 0 0 0 0 0 0 0 0 0 0 0 9.10287 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BQQ7 RTP3_HUMAN Receptor-transporting protein 3 (3CxxC-type zinc finger protein 3) (Transmembrane protein 7) RTP3 TMEM7 Z3CXXC3 Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; protein insertion into membrane [GO:0051205]; protein targeting to membrane [GO:0006612] cytoplasm [GO:0005737]; membrane [GO:0016020] metal ion binding [GO:0046872]; olfactory receptor binding [GO:0031849] 0.90211 -0.70275 EVKPWHR 0 0 0 11.5508 0 0 11.1306 0 9.49789 0 0 12.4056 0 0 0 0 0 0 0 9.7413 0 9.67248 0 0 0 0 0 Q9BQS6 HSPB9_HUMAN Heat shock protein beta-9 (HspB9) (Cancer/testis antigen 51) (CT51) HSPB9 Homo sapiens (Human) cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.96775 -2.8899 LGSLGSKASNLTR 0 0 0 0 0 0 0 0 8.82474 0 0 0 0 0 0 0 0 0 10.4113 0 0 0 9.9486 0 0 0 0 Q9BQS8 FYCO1_HUMAN FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7) FYCO1 ZFYVE7 Homo sapiens (Human) plus-end-directed vesicle transport along microtubule [GO:0072383]; positive regulation of autophagosome maturation [GO:1901098] autophagosome [GO:0005776]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020] metal ion binding [GO:0046872] 0.9632 -2.1219 ELLEQEVR 0 0 0 0 9.79594 0 10.6796 0 0 10.3966 0 10.7811 10.4406 10.2297 10.4244 0 0 0 0 0 0 0 0 0 0 10.615 0 Q9BQY9 DBND2_HUMAN Dysbindin domain-containing protein 2 (Casein kinase-1 binding protein) (CK1BP) (HSMNP1) DBNDD2 C20orf35 Homo sapiens (Human) negative regulation of protein kinase activity [GO:0006469] cytoplasm [GO:0005737] 0.95304 -1.4723 AALERQQLR 10.5108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BR26 OCSTP_HUMAN Osteoclast stimulatory transmembrane protein (OC-STAMP) OCSTAMP C20orf123 Homo sapiens (Human) cellular response to estrogen stimulus [GO:0071391]; cellular response to tumor necrosis factor [GO:0071356]; multinuclear osteoclast differentiation [GO:0072674]; positive regulation of macrophage fusion [GO:0034241]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of osteoclast proliferation [GO:0090290] membrane [GO:0016020] 0.83524 0.18595 SLHLSEPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.41908 0 0 0 Q9BR39 JPH2_HUMAN Junctophilin-2 (JP-2) (Junctophilin type 2) [Cleaved into: Junctophilin-2 N-terminal fragment (JP2NT)] JPH2 JP2 Homo sapiens (Human) calcium ion homeostasis [GO:0055074]; calcium ion transport into cytosol [GO:0060402]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle tissue development [GO:0055024]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314] endoplasmic reticulum membrane [GO:0005789]; junctional membrane complex [GO:0030314]; junctional sarcoplasmic reticulum membrane [GO:0014701]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018] "core promoter sequence-specific DNA binding [GO:0001046]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatidic acid binding [GO:0070300]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; phosphatidylserine binding [GO:0001786]" 0.92173 -1.134 SGFGVSERSSGLRYEGEWLDNLR 0 0 0 10.5447 0 0 0 0 0 0 14.2734 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BR76 COR1B_HUMAN Coronin-1B (Coronin-2) CORO1B Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; cell migration [GO:0016477]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; endothelial cell chemotaxis [GO:0035767]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; positive regulation of lamellipodium morphogenesis [GO:2000394]; protein localization to cell leading edge [GO:1902463]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315]; ruffle organization [GO:0031529]; wound healing [GO:0042060] actin filament [GO:0005884]; cell leading edge [GO:0031252]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; stress fiber [GO:0001725] actin filament binding [GO:0051015]; Arp2/3 complex binding [GO:0071933]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802] 0.026608 1.5425 DADPILISLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.01179 8.86895 8.84536 8.86316 9.17103 8.9695 10.8941 10.8558 10.1412 Q9BR77 CCD77_HUMAN Coiled-coil domain-containing protein 77 CCDC77 Homo sapiens (Human) centrosome [GO:0005813]; membrane [GO:0016020] 0.92365 -1.0704 EQIEGLIEDRR 0 0 0 0 0 0 0 0 9.0604 0 0 0 0 0 0 0 0 0 0 9.70482 0 0 0 0 0 0 9.81429 Q9BR84 ZN559_HUMAN Zinc finger protein 559 ZNF559 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.93264 -1.2661 VLPIEHKKFGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1615 0 0 Q9BRB3 PIGQ_HUMAN Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q (N-acetylglucosamyl transferase component GPI1) (Phosphatidylinositol-glycan biosynthesis class Q protein) (PIG-Q) PIGQ GPI1 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; GPI anchor biosynthetic process [GO:0006506] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex [GO:0000506] 0.8796 0.00484 HPLAPSAEQHPASGGLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.149 0 0 Q9BRC7 PLCD4_HUMAN "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (hPLCD4) (EC 3.1.4.11) (Phosphoinositide phospholipase C-delta-4) (Phospholipase C-delta-4) (PLC-delta-4)" PLCD4 Homo sapiens (Human) acrosome reaction [GO:0007340]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; small GTPase mediated signal transduction [GO:0007264] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nucleus [GO:0005634]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; G-protein alpha-subunit binding [GO:0001965]; guanyl-nucleotide exchange factor activity [GO:0005085]; phosphatidylinositol phospholipase C activity [GO:0004435] 0.58969 0.45254 VLVPELAMLR 0 11.8878 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BRD0 BUD13_HUMAN BUD13 homolog BUD13 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; U2-type prespliceosome assembly [GO:1903241]" nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RES complex [GO:0070274]; spliceosomal complex [GO:0005681]; U2 snRNP [GO:0005686]; U2-type precatalytic spliceosome [GO:0071005]; U2-type spliceosomal complex [GO:0005684] RNA binding [GO:0003723] 0.95288 -1.4893 AVEELAYK 18.1614 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2426 9.48238 0 0 0 Q9BRG1 VPS25_HUMAN Vacuolar protein-sorting-associated protein 25 (hVps25) (Dermal papilla-derived protein 9) (ELL-associated protein of 20 kDa) (ESCRT-II complex subunit VPS25) VPS25 DERP9 EAP20 Homo sapiens (Human) macroautophagy [GO:0016236]; membrane fission [GO:0090148]; multivesicular body assembly [GO:0036258]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; ESCRT II complex [GO:0000814]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] protein homodimerization activity [GO:0042803]; structural molecule activity [GO:0005198] 0.92161 -0.93886 AMSFEWPWQYR 0 13.8785 13.7757 0 10.4609 0 12.7653 13.055 0 0 0 0 0 0 0 13.2228 0 0 0 0 0 0 0 0 0 0 0 Q9BRG2 SH23A_HUMAN SH2 domain-containing protein 3A (Novel SH2-containing protein 1) SH2D3A NSP1 UNQ175/PRO201 Homo sapiens (Human) JNK cascade [GO:0007254]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; small GTPase mediated signal transduction [GO:0007264] guanyl-nucleotide exchange factor activity [GO:0005085]; phosphotyrosine residue binding [GO:0001784] 0.95402 -1.5229 TLHGARHMVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7172 0 0 0 0 0 0 0 0 0 0 0 0 Q9BRH9 ZN251_HUMAN Zinc finger protein 251 ZNF251 Homo sapiens (Human) hematopoietic stem cell homeostasis [GO:0061484]; regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96207 -2.5542 FSEEVKTPEFVSR 0 14.3797 0 0 9.8981 0 0 0 0 0 0 0 0 10.9259 10.6858 0 0 0 0 10.4005 0 0 0 0 0 0 0 Q9BRJ2 RM45_HUMAN "Large ribosomal subunit protein mL45 (39S ribosomal protein L45, mitochondrial) (L45mt) (MRP-L45)" MRPL45 Homo sapiens (Human) mitochondrial translation [GO:0032543] mitochondrial inner membrane [GO:0005743]; mitochondrial large ribosomal subunit [GO:0005762]; mitochondrion [GO:0005739] RNA binding [GO:0003723] 0.95107 -1.4153 FKTEKEFMQHAR 0 0 0 0 0 0 10.9413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BRK4 LZTS2_HUMAN Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1) LZTS2 KIAA1813 LAPSER1 Homo sapiens (Human) microtubule severing [GO:0051013]; mitotic cytokinesis [GO:0000281]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; nuclear export [GO:0051168]; spindle midzone assembly [GO:0051255]; Wnt signaling pathway [GO:0016055] centrosome [GO:0005813]; cytosol [GO:0005829]; microtubule [GO:0005874]; midbody [GO:0030496]; plasma membrane [GO:0005886]; vesicle [GO:0031982] 0.96777 -2.9416 CATLEREQR 0 0 0 0 0 0 0 0 0 0 0 8.59096 0 0 0 0 0 0 0 8.63372 0 0 0 0 0 0 0 Q9BRL7 SC22C_HUMAN Vesicle-trafficking protein SEC22c (SEC22 vesicle-trafficking protein homolog C) (SEC22 vesicle-trafficking protein-like 3) SEC22C SEC22L3 UNQ459/PRO784 Homo sapiens (Human) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein transport [GO:0015031] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] 0.96893 -3.3761 LAQYPGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.8831 0 Q9BRP1 PDD2L_HUMAN Programmed cell death protein 2-like PDCD2L Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049] cytoplasm [GO:0005737]; membrane [GO:0016020] 0.93347 -1.2836 EGIAMDQLLSQSLPNDGDEKYEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.49043 0 0 0 Q9BRP4 PAAF1_HUMAN Proteasomal ATPase-associated factor 1 (Protein G-16) (WD repeat-containing protein 71) PAAF1 WDR71 Homo sapiens (Human) transcription initiation at RNA polymerase II promoter [GO:0006367] proteasome complex [GO:0000502]; transcription factor TFIID complex [GO:0005669] 0.95997 -1.9017 APVQVIHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.029 0 0 Q9BRP7 FDXA1_HUMAN Ferredoxin-fold anticodon-binding domain-containing protein 1 (FDX-ACDB domain-containing protein 1) FDXACB1 Homo sapiens (Human) rRNA base methylation [GO:0070475] cytoplasm [GO:0005737] rRNA (uridine-N3-)-methyltransferase activity [GO:0070042] 0.86983 0.039829 NPGRDGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.86216 0 0 0 0 Q9BRP8 PYM1_HUMAN Partner of Y14 and mago (PYM homolog 1 exon junction complex-associated factor) (Protein wibg homolog) PYM1 PYM WIBG Homo sapiens (Human) "exon-exon junction complex disassembly [GO:1903259]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of translation [GO:0045727]" cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; exon-exon junction complex [GO:0035145]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] ribosome binding [GO:0043022]; RNA binding [GO:0003723] 0.8458 0.17449 QVEELQQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.90758 0 Q9BRP9 YK016_HUMAN Putative uncharacterized protein MGC13053 Homo sapiens (Human) 0.88718 -0.36068 EGEGRCEQVALSSGPPEGALHASR 8.68349 0 0 0 8.7212 0 0 0 0 0 9.10205 0 0 9.03009 9.06824 8.6143 8.60899 11.4249 0 0 0 8.75802 0 9.03593 0 0 0 Q9BRQ4 CF300_HUMAN Cilia- and flagella-associated protein 300 CFAP300 C11orf70 Homo sapiens (Human) cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; motile cilium [GO:0031514] 0.84222 0.18304 VLLVEDSEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2955 0 0 0 0 0 0 0 0 Q9BRR0 ZKSC3_HUMAN Zinc finger protein with KRAB and SCAN domains 3 (Zinc finger and SCAN domain-containing protein 13) (Zinc finger protein 306) (Zinc finger protein 309) (Zinc finger protein 47 homolog) (Zf47) (Zfp-47) ZKSCAN3 ZFP47 ZNF306 ZNF309 ZSCAN13 Homo sapiens (Human) autophagy [GO:0006914]; lysosome organization [GO:0007040]; negative regulation of autophagy [GO:0010507]; negative regulation of cellular senescence [GO:2000773]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357] cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]" 0.9153 -0.79531 RHICHECGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.8906 0 0 0 0 0 0 0 0 0 0 0 Q9BRR3 PGAP4_HUMAN Post-GPI attachment to proteins factor 4 (Post-GPI attachment to proteins GalNAc transferase 4) (Transmembrane protein 246) PGAP4 C9orf125 TMEM246 Homo sapiens (Human) GPI anchor biosynthetic process [GO:0006506] Golgi membrane [GO:0000139] glycosyltransferase activity [GO:0016757] 0.90343 -0.70474 HYFLELR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.496 10.5636 0 0 Q9BRR8 GPTC1_HUMAN G patch domain-containing protein 1 (Evolutionarily conserved G-patch domain-containing protein) GPATCH1 ECGP GPATC1 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]" catalytic step 2 spliceosome [GO:0071013]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] RNA binding [GO:0003723] 0.97022 -3.2443 ASNFKPFAK 8.92083 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3371 Q9BRR9 RHG09_HUMAN Rho GTPase-activating protein 9 (Rho-type GTPase-activating protein 9) ARHGAP9 Homo sapiens (Human) regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; secretory granule lumen [GO:0034774] "GTPase activator activity [GO:0005096]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]" 0.92159 -1.1268 AVTSDGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.6689 0 0 9.73574 0 0 0 0 11.1599 0 0 0 0 Q9BRS8 LARP6_HUMAN La-related protein 6 (Acheron) (Achn) (La ribonucleoprotein domain family member 6) LARP6 Homo sapiens (Human) positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of mRNA binding [GO:1902416]; positive regulation of translation [GO:0045727]; RNA processing [GO:0006396] cytoplasm [GO:0005737]; nucleus [GO:0005634]; polysome [GO:0005844]; ribonucleoprotein complex [GO:1990904] mRNA 5'-UTR binding [GO:0048027]; mRNA binding [GO:0003729]; myosin binding [GO:0017022]; RNA stem-loop binding [GO:0035613]; sequence-specific mRNA binding [GO:1990825] 0.91854 -0.89022 GAGDPAR 10.4879 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.69822 0 0 0 Q9BRT2 UQCC2_HUMAN Ubiquinol-cytochrome-c reductase complex assembly factor 2 (Breast cancer-associated protein SGA-81M) (Mitochondrial nucleoid factor 1) (Mitochondrial protein M19) UQCC2 C6orf125 MNF1 Homo sapiens (Human) mitochondrial respiratory chain complex III assembly [GO:0034551]; positive regulation of mitochondrial translation [GO:0070131]; regulation of insulin secretion [GO:0050796]; regulation of oxidative phosphorylation [GO:0002082]; regulation of skeletal muscle cell differentiation [GO:2001014] mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; nuclear body [GO:0016604] 0.32161 0.78787 AASRYRR 0 0 0 0 0 0 0 0 0 8.3117 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.89266 0 0 Q9BRU2 TCAL7_HUMAN Transcription elongation factor A protein-like 7 (TCEA-like protein 7) (Transcription elongation factor S-II protein-like 7) TCEAL7 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of NF-kappaB transcription factor activity [GO:0032088] nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.93249 -1.2768 EDIDYRHFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.19343 0 0 9.0212 0 0 0 0 Q9BRX8 PXL2A_HUMAN Peroxiredoxin-like 2A (Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes) (Protein PAMM) (Redox-regulatory protein FAM213A) PRXL2A C10orf58 FAM213A PAMM PRO2290 PSEC0139 UNQ611/PRO1198 Homo sapiens (Human) regulation of osteoclast differentiation [GO:0045670] cytoplasm [GO:0005737]; extracellular region [GO:0005576] antioxidant activity [GO:0016209] 0.96357 -2.6427 EEAADLSSLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.9969 0 10.2965 0 0 0 0 0 0 0 0 10.5083 0 Q9BRX9 WDR83_HUMAN WD repeat domain-containing protein 83 (Mitogen-activated protein kinase organizer 1) (MAPK organizer 1) WDR83 MORG1 Homo sapiens (Human) "inflammatory response to wounding [GO:0090594]; mRNA splicing, via spliceosome [GO:0000398]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; RNA splicing, via transesterification reactions [GO:0000375]" catalytic step 2 spliceosome [GO:0071013]; endosome membrane [GO:0010008]; spliceosomal complex [GO:0005681] 0.80186 0.24143 DGQCTLVSSLDSTLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0474 0 0 0 0 0 0 0 0 0 0 Q9BRZ2 TRI56_HUMAN E3 ubiquitin-protein ligase TRIM56 (EC 2.3.2.27) (RING finger protein 109) (Tripartite motif-containing protein 56) TRIM56 RNF109 Homo sapiens (Human) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; regulation of type I interferon production [GO:0032479]; response to type I interferon [GO:0034340] cytoplasm [GO:0005737]; cytosol [GO:0005829] molecular function activator activity [GO:0140677]; RNA binding [GO:0003723]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.10536 1.1424 DGAGTQGGEESQSRR 0 0 0 0 0 0 0 0 8.98467 0 9.42666 9.50458 0 0 0 0 0 0 0 0 0 0 9.06762 0 0 0 0 Q9BS34 ZN670_HUMAN Zinc finger protein 670 ZNF670 Homo sapiens (Human) cellular lipid metabolic process [GO:0044255]; lipid metabolic process [GO:0006629]; regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96265 -2.0852 SFTSSSALR 11.9045 11.711 11.6879 0 9.43392 9.55568 10.9653 10.9076 10.9914 0 13.2616 0 10.8619 0 0 0 0 0 0 0 0 0 10.1948 0 0 0 0 Q9BS91 S35A5_HUMAN Probable UDP-sugar transporter protein SLC35A5 (Solute carrier family 35 member A5) SLC35A5 UNQ164/PRO190 Homo sapiens (Human) carbohydrate transport [GO:0008643] Golgi membrane [GO:0000139] pyrimidine nucleotide-sugar transmembrane transporter activity [GO:0015165] 0.95435 -1.5013 IRDLSGNLWER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.03488 0 0 0 0 Q9BSA4 TTYH2_HUMAN Protein tweety homolog 2 (hTTY2) TTYH2 C17orf29 Homo sapiens (Human) chloride channel complex [GO:0034707]; plasma membrane [GO:0005886] intracellular calcium activated chloride channel activity [GO:0005229]; volume-sensitive chloride channel activity [GO:0072320] 0.5139 0.60225 EVTMELTK 11.4167 11.3119 11.3232 9.79875 0 0 0 0 0 12.9441 12.4576 12.986 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BSC4 NOL10_HUMAN Nucleolar protein 10 NOL10 Homo sapiens (Human) "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]" nucleolus [GO:0005730]; small-subunit processome [GO:0032040] RNA binding [GO:0003723] 0.7874 0.2498 IYSLSCGK 0 0 0 0 0 0 0 0 0 0 0 0 9.43461 0 0 0 0 0 0 0 9.19756 0 0 0 0 0 0 Q9BSD3 RHNO1_HUMAN "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 (RAD9, RAD1, HUS1-interacting nuclear orphan protein)" RHNO1 C12orf32 RHINO HKMT1188 Homo sapiens (Human) cell cycle [GO:0007049]; cellular response to ionizing radiation [GO:0071479]; cellular response to UV [GO:0034644]; DNA damage checkpoint signaling [GO:0000077]; positive regulation of G0 to G1 transition [GO:0070318]; recombinational repair [GO:0000725] chromosome [GO:0005694]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.91569 -0.77621 RRQHLLAYLR 0 0 0 0 0 0 10.9929 0 9.76454 0 0 0 11.5353 10.0897 0 0 0 0 9.97957 0 0 0 0 0 0 0 0 Q9BSD7 NTPCR_HUMAN Cancer-related nucleoside-triphosphatase (NTPase) (EC 3.6.1.15) (Nucleoside triphosphate phosphohydrolase) NTPCR C1orf57 Homo sapiens (Human) membrane [GO:0016020] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; CTPase activity [GO:0043273]; GTPase activity [GO:0003924]; ribonucleoside triphosphate phosphatase activity [GO:0017111]; RNA binding [GO:0003723] 0.9546 -1.5221 TTLIHKASEVLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.9028 Q9BSE5 GDAH_HUMAN "Guanidino acid hydrolase, mitochondrial (EC 3.5.3.-) (Arginase, mitochondrial) (EC 3.5.3.1) (Guanidinobutyrase, mitochondrial) (EC 3.5.3.7) (Guanidinopropionase, mitochondrial) (EC 3.5.3.17)" AGMAT GDAH Homo sapiens (Human) "agmatine biosynthetic process [GO:0097055]; putrescine biosynthetic process from arginine, using agmatinase [GO:0033389]; spermidine biosynthetic process [GO:0008295]" mitochondrion [GO:0005739] agmatinase activity [GO:0008783]; metal ion binding [GO:0046872] 0.69461 0.38388 IQEAYEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.78051 8.74457 0 0 0 0 0 0 0 0 0 0 Q9BSF4 TIM29_HUMAN Mitochondrial import inner membrane translocase subunit Tim29 (TIM29) TIMM29 c19orf52 Homo sapiens (Human) protein insertion into mitochondrial inner membrane [GO:0045039] mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; TIM22 mitochondrial import inner membrane insertion complex [GO:0042721] protein transporter activity [GO:0140318] 0.96125 -2.5603 DASAEAR 0 0 0 0 0 0 0 0 0 0 9.41517 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BSF8 BTBDA_HUMAN BTB/POZ domain-containing protein 10 (Glucose metabolism-related protein 1) BTBD10 GMRP1 Homo sapiens (Human) positive regulation of phosphorylation [GO:0042327]; protein kinase B signaling [GO:0043491]; type B pancreatic cell proliferation [GO:0044342] cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654] 0.8491 0.15813 DHSSSRPSSPRPQK 0 0 0 0 9.16277 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BSH4 TACO1_HUMAN Translational activator of cytochrome c oxidase 1 (Coiled-coil domain-containing protein 44) (Translational activator of mitochondrially-encoded cytochrome c oxidase I) TACO1 CCDC44 PRO0477 Homo sapiens (Human) mitochondrial cytochrome c oxidase assembly [GO:0033617]; motor learning [GO:0061743]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of mitochondrial translation [GO:0070129] mitochondrion [GO:0005739] mitochondrial ribosome binding [GO:0097177]; mRNA binding [GO:0003729]; rRNA binding [GO:0019843] 0.87334 0.032188 GVIVVEVEDR 0 0 0 0 0 0 0 0 0 0 9.23009 0 0 0 0 0 0 0 0 0 0 0 0 0 8.37656 0 0 Q9BSI4 TINF2_HUMAN TERF1-interacting nuclear factor 2 (TRF1-interacting nuclear protein 2) TINF2 TIN2 Homo sapiens (Human) "negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein ADP-ribosylation [GO:0010836]; negative regulation of telomere maintenance via telomerase [GO:0032211]; positive regulation of telomere maintenance [GO:0032206]; protein localization to chromosome, telomeric region [GO:0070198]; regulation of telomere maintenance via telomere lengthening [GO:1904356]; telomere assembly [GO:0032202]; telomere capping [GO:0016233]" "chromosome, telomeric region [GO:0000781]; nuclear body [GO:0016604]; nuclear matrix [GO:0016363]; nuclear telomere cap complex [GO:0000783]; nucleoplasm [GO:0005654]; perinucleolar chromocenter [GO:0010370]; shelterin complex [GO:0070187]" telomeric DNA binding [GO:0042162] 0.95812 -1.6705 ESLENYQKTK 0 0 0 0 0 10.4722 0 0 0 0 0 0 0 0 9.17712 0 0 0 0 0 9.60303 0 0 0 0 0 9.97857 Q9BSJ2 GCP2_HUMAN Gamma-tubulin complex component 2 (GCP-2) (hGCP2) (Gamma-ring complex protein 103 kDa) (h103p) (hGrip103) (Spindle pole body protein Spc97 homolog) (hSpc97) TUBGCP2 GCP2 Homo sapiens (Human) brain development [GO:0007420]; cytoplasmic microtubule organization [GO:0031122]; meiotic cell cycle [GO:0051321]; microtubule nucleation [GO:0007020]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; protein-containing complex assembly [GO:0065003]; spindle assembly [GO:0051225] centrosome [GO:0005813]; cytoplasmic microtubule [GO:0005881]; cytosol [GO:0005829]; equatorial microtubule organizing center [GO:0000923]; gamma-tubulin complex [GO:0000930]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; nucleoplasm [GO:0005654]; spindle pole [GO:0000922] gamma-tubulin binding [GO:0043015] 0.95902 -1.7669 LDFNGFYTERLERLSAER 0 0 0 0 0 0 9.19478 0 0 0 0 0 0 0 9.60144 0 0 0 0 0 0 0 9.56634 0 11.1172 0 10.293 Q9BSJ5 CQ080_HUMAN Uncharacterized protein C17orf80 (Cell migration-inducing gene 3 protein) (Human lung cancer oncogene 8 protein) (HLC-8) C17orf80 HLC8 MIG3 Homo sapiens (Human) extracellular exosome [GO:0070062]; membrane [GO:0016020] 0.84821 0.12514 QERTVMSHGCENFNTRDSVTGK 0 10.0595 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BSJ8 ESYT1_HUMAN Extended synaptotagmin-1 (E-Syt1) (Membrane-bound C2 domain-containing protein) ESYT1 FAM62A KIAA0747 MBC2 Homo sapiens (Human) endoplasmic reticulum-plasma membrane tethering [GO:0061817]; intermembrane lipid transfer [GO:0120009] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; identical protein binding [GO:0042802]; phosphatidylcholine binding [GO:0031210]; phosphatidylethanolamine binding [GO:0008429]; phosphatidylinositol binding [GO:0035091]; phospholipid transfer activity [GO:0120014] 0.057732 1.3886 AEDLPLRK 0 0 0 0 9.00523 0 0 9.09679 0 0 0 0 0 0 0 9.26303 0 0 0 0 0 0 0 0 0 0 0 Q9BSK1 ZN577_HUMAN Zinc finger protein 577 ZNF577 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.87175 0.035023 AFAHMSVLIK 0 0 0 0 0 0 0 0 0 0 8.45935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BSK2 S2533_HUMAN Solute carrier family 25 member 33 (Bone marrow stromal cell mitochondrial carrier protein) (BMSC-MCP) (HuBMSC-MCP) (Protein PNC1) SLC25A33 Homo sapiens (Human) cellular response to insulin stimulus [GO:0032869]; cellular response to insulin-like growth factor stimulus [GO:1990314]; mitochondria-nucleus signaling pathway [GO:0031930]; mitochondrial genome maintenance [GO:0000002]; mitochondrial respiratory chain complex III assembly [GO:0034551]; mitochondrial transcription [GO:0006390]; mitochondrion organization [GO:0007005]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; pyrimidine nucleotide import into mitochondrion [GO:1990519]; pyrimidine nucleotide transport [GO:0006864]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of oxidative phosphorylation [GO:0002082]; regulation of reactive oxygen species biosynthetic process [GO:1903426] mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739] pyrimidine nucleotide transmembrane transporter activity [GO:0015218] 0.55882 0.54648 AVYFACYSK 0 0 0 0 0 0 0 10.4228 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BSM1 PCGF1_HUMAN Polycomb group RING finger protein 1 (Nervous system Polycomb-1) (NSPc1) (RING finger protein 68) PCGF1 NSPC1 RNF68 Homo sapiens (Human) chromatin remodeling [GO:0006338]; histone H2A-K119 monoubiquitination [GO:0036353]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PcG protein complex [GO:0031519]; PRC1 complex [GO:0035102] metal ion binding [GO:0046872]; promoter-specific chromatin binding [GO:1990841] 0.96295 -2.1475 NEEEVRVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.88425 0 0 0 0 Q9BST9 RTKN_HUMAN Rhotekin RTKN RTKN1 Homo sapiens (Human) actomyosin contractile ring assembly [GO:0000915]; apoptotic process [GO:0006915]; mitotic cytokinesis [GO:0000281]; regulation of apoptotic process [GO:0042981]; Rho protein signal transduction [GO:0007266]; septin ring organization [GO:0031106]; signal transduction [GO:0007165] actomyosin contractile ring [GO:0005826]; cytosol [GO:0005829] GTP binding [GO:0005525]; GTPase inhibitor activity [GO:0005095]; small GTPase binding [GO:0031267] 0.90908 -0.74574 ILSYMGELQRR 0 0 0 0 0 0 0 0 0 12.2112 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BSW2 EFC4B_HUMAN EF-hand calcium-binding domain-containing protein 4B (Calcium release-activated calcium channel regulator 2A) (CRAC channel regulator 2A) (Calcium release-activated channel regulator 2A) (Ras-related protein Rab-46) CRACR2A EFCAB4B RAB46 Homo sapiens (Human) activation of store-operated calcium channel activity [GO:0032237]; adaptive immune response [GO:0002250]; endosomal transport [GO:0016197]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of JNK cascade [GO:0046330]; response to histamine [GO:0034776]; store-operated calcium entry [GO:0002115]; T-helper 1 cell differentiation [GO:0045063] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; immunological synapse [GO:0001772]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; plasma membrane [GO:0005886]; specific granule lumen [GO:0035580]; trans-Golgi network membrane [GO:0032588]; vesicle [GO:0031982]; Weibel-Palade body [GO:0033093] calcium ion binding [GO:0005509]; GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.95937 -1.9508 AQEFFQTCDAEGK 0 0 0 0 0 0 13.0097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BT09 CNPY3_HUMAN Protein canopy homolog 3 (CTG repeat protein 4a) (Expanded repeat-domain protein CAG/CTG 5) (Protein associated with TLR4) (Trinucleotide repeat-containing gene 5 protein) CNPY3 CTG4A ERDA5 PRAT4A TNRC5 HSPC084 UNQ1934/PRO4409 Homo sapiens (Human) innate immune response [GO:0045087] endoplasmic reticulum lumen [GO:0005788] signaling receptor binding [GO:0005102] 0.13357 1.0568 AKAAGGR 0 0 0 9.72945 0 9.77091 0 0 0 12.7113 0 0 0 0 0 0 10.642 0 0 0 0 0 0 0 0 0 0 Q9BT25 HAUS8_HUMAN HAUS augmin-like complex subunit 8 (HEC1/NDC80-interacting centrosome-associated protein 1) (Sarcoma antigen NY-SAR-48) HAUS8 HICE1 Homo sapiens (Human) cell division [GO:0051301]; centrosome cycle [GO:0007098]; spindle assembly [GO:0051225] centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; HAUS complex [GO:0070652]; mitotic spindle microtubule [GO:1990498]; nuclear microtubule [GO:0005880]; spindle pole [GO:0000922] microtubule binding [GO:0008017] 0.96742 -2.7976 ADSSGVGK 0 9.27608 0 0 0 0 8.35451 8.54419 0 9.54834 0 0 0 0 0 0 0 0 0 0 0 0 0 9.39701 0 0 0 Q9BT30 ALKB7_HUMAN "Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 7) (Spermatogenesis cell proliferation-related protein) (Spermatogenesis-associated protein 11)" ALKBH7 ABH7 SPATA11 UNQ6002/PRO34564 Homo sapiens (Human) DNA damage response [GO:0006974]; fatty acid metabolic process [GO:0006631]; regulation of lipid storage [GO:0010883]; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [GO:1902445] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872] 0.93301 -1.2792 ELEPELRRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.61787 0 Q9BT78 CSN4_HUMAN COP9 signalosome complex subunit 4 (SGN4) (Signalosome subunit 4) (JAB1-containing signalosome subunit 4) COPS4 CSN4 Homo sapiens (Human) protein deneddylation [GO:0000338]; protein neddylation [GO:0045116]; regulation of protein neddylation [GO:2000434] cell junction [GO:0030054]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; synaptic vesicle [GO:0008021] deNEDDylase activity [GO:0019784] 0.82433 0.21499 ATTADGSSILDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.75442 0 0 0 0 Q9BT88 SYT11_HUMAN Synaptotagmin-11 (Synaptotagmin XI) (SytXI) SYT11 KIAA0080 Homo sapiens (Human) autophagy [GO:0006914]; calcium ion regulated lysosome exocytosis [GO:1990927]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cellular response to calcium ion [GO:0071277]; establishment of vesicle localization [GO:0051650]; learning [GO:0007612]; memory [GO:0007613]; negative regulation of cytokine production [GO:0001818]; negative regulation of dopamine secretion [GO:0033602]; negative regulation of endocytosis [GO:0045806]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of neurotransmitter secretion [GO:0046929]; negative regulation of phagocytosis [GO:0050765]; negative regulation of tumor necrosis factor production [GO:0032720]; plasma membrane repair [GO:0001778]; positive regulation of protein localization to phagocytic vesicle [GO:1905171]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of defense response to bacterium [GO:1900424]; regulation of dopamine secretion [GO:0014059]; regulation of phagosome maturation [GO:1905162]; regulation of synaptic vesicle endocytosis [GO:1900242]; vesicle fusion [GO:0006906] axon [GO:0030424]; clathrin-coated vesicle membrane [GO:0030665]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; dopaminergic synapse [GO:0098691]; early phagosome [GO:0032009]; excitatory synapse [GO:0060076]; inhibitory synapse [GO:0060077]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; phagocytic cup [GO:0001891]; phagocytic vesicle [GO:0045335]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; presynaptic active zone membrane [GO:0048787]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; vesicle [GO:0031982] beta-tubulin binding [GO:0048487]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; phosphatidylserine binding [GO:0001786]; SNARE binding [GO:0000149]; translation initiation factor binding [GO:0031369]; ubiquitin protein ligase binding [GO:0031625] 0.8692 0.067365 LILGAHSVTASGAEHWR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0532 0 0 Q9BT92 TCHP_HUMAN Trichoplein keratin filament-binding protein (Protein TCHP) (Mitochondrial protein with oncostatic activity) (Mitostatin) (Tumor suppressor protein) TCHP Homo sapiens (Human) apoptotic process [GO:0006915]; cell projection organization [GO:0030030]; negative regulation of cell growth [GO:0030308]; negative regulation of cilium assembly [GO:1902018] apical cortex [GO:0045179]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; desmosome [GO:0030057]; keratin filament [GO:0045095]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886] 0.89727 -0.53131 ALPTLPSYWCSQQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.55211 0 0 Q9BTA9 WAC_HUMAN WW domain-containing adapter protein with coiled-coil WAC KIAA1844 Homo sapiens (Human) chromatin remodeling [GO:0006338]; DNA damage response [GO:0006974]; histone monoubiquitination [GO:0010390]; mitotic G1 DNA damage checkpoint signaling [GO:0031571]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of macroautophagy [GO:0016239]; positive regulation of TORC1 signaling [GO:1904263]; regulation of autophagy [GO:0010506] nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681] chromatin binding [GO:0003682]; RNA polymerase II complex binding [GO:0000993] 0.95935 -1.7304 EEAHNMGTIHMSEICTELK 0 0 0 0 0 0 0 0 10.238 0 0 0 0 0 0 0 9.2861 0 0 0 0 0 0 0 0 0 0 Q9BTC0 DIDO1_HUMAN Death-inducer obliterator 1 (DIO-1) (hDido1) (Death-associated transcription factor 1) (DATF-1) DIDO1 C20orf158 DATF1 KIAA0333 Homo sapiens (Human) apoptotic signaling pathway [GO:0097190]; DNA-templated transcription [GO:0006351] cytoplasm [GO:0005737]; nucleus [GO:0005634]; spindle [GO:0005819] metal ion binding [GO:0046872]; RNA binding [GO:0003723] 0.96995 -5.2462 EWDRSRER 9.09666 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2913 0 0 0 0 11.5645 0 0 12.4671 0 0 0 0 Q9BTC8 MTA3_HUMAN Metastasis-associated protein MTA3 MTA3 KIAA1266 Homo sapiens (Human) chromatin remodeling [GO:0006338]; G2/M transition of mitotic cell cycle [GO:0000086]; granulosa cell proliferation [GO:1990739]; histone deacetylation [GO:0016575]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of granulosa cell proliferation [GO:1904197]; regulation of cell fate specification [GO:0042659]; regulation of stem cell differentiation [GO:2000736] cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NuRD complex [GO:0016581] chromatin binding [GO:0003682]; histone deacetylase binding [GO:0042826]; metal ion binding [GO:0046872]; NuRD complex binding [GO:0120325]; sequence-specific DNA binding [GO:0043565]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714] 0.96271 -2.1813 AAEAESK 0 0 0 0 0 0 0 0 8.20965 0 0 0 0 0 0 0 0 9.73574 0 0 0 0 0 0 0 12.4367 0 Q9BTD8 RBM42_HUMAN RNA-binding protein 42 (RNA-binding motif protein 42) RBM42 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]" cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U4/U6 x U5 tri-snRNP complex [GO:0046540] mRNA binding [GO:0003729]; RNA binding [GO:0003723] 0.96402 -2.1043 AFSRFPSFLKAK 18.1614 18.3765 0 0 14.3104 0 9.93173 8.33807 18.1839 8.53955 9.5819 0 0 14.75 0 9.26205 16.3788 16.2693 0 0 0 0 0 0 12.3067 0 10.1311 Q9BTE1 DCTN5_HUMAN Dynactin subunit 5 (Dynactin subunit p25) DCTN5 Homo sapiens (Human) aorta development [GO:0035904]; coronary vasculature development [GO:0060976]; ventricular septum development [GO:0003281] centrosome [GO:0005813]; cytosol [GO:0005829]; dynactin complex [GO:0005869]; kinetochore [GO:0000776]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654] 0.81332 0.22197 MELGELLYNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.9319 0 Q9BTE6 AASD1_HUMAN Alanyl-tRNA editing protein Aarsd1 (Alanyl-tRNA synthetase domain-containing protein 1) AARSD1 Homo sapiens (Human) alanyl-tRNA aminoacylation [GO:0006419]; regulation of translational fidelity [GO:0006450] cytoplasm [GO:0005737]; nucleus [GO:0005634] alanine-tRNA ligase activity [GO:0004813]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; Ser-tRNA(Ala) hydrolase activity [GO:0002196] 0.56494 0.49041 ELSLDDPEVEQVSGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.93852 0 0 0 0 0 0 0 Q9BTE7 DCNL5_HUMAN DCN1-like protein 5 (DCNL5) (DCUN1 domain-containing protein 5) (Defective in cullin neddylation protein 1-like protein 5) (Squamous cell carcinoma-related oncogene 5) DCUN1D5 SCCRO5 Homo sapiens (Human) DNA damage response [GO:0006974]; positive regulation of protein neddylation [GO:2000436]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein neddylation [GO:0045116]; regulation of cell growth [GO:0001558]; regulation of protein neddylation [GO:2000434] cytoplasm [GO:0005737]; nucleus [GO:0005634]; spindle [GO:0005819]; ubiquitin ligase complex [GO:0000151] cullin family protein binding [GO:0097602]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin-like protein binding [GO:0032182] 0.96969 -5.0421 KCKISSYCR 0 0 11.2309 0 9.02511 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1585 0 0 0 0 0 0 0 Q9BTF0 THUM2_HUMAN THUMP domain-containing protein 2 THUMPD2 C2orf8 Homo sapiens (Human) tRNA methylation [GO:0030488] RNA binding [GO:0003723]; tRNA (guanine) methyltransferase activity [GO:0016423] 0.85082 0.16043 LSQRDDNQLK 0 0 0 0 0 0 0 0 0 9.59811 0 0 0 0 0 0 0 0 0 0 0 0 9.94457 0 0 0 0 Q9BTT6 LRRC1_HUMAN Leucine-rich repeat-containing protein 1 (LANO adapter protein) (LAP and no PDZ protein) LRRC1 LANO Homo sapiens (Human) cytosol [GO:0005829]; membrane [GO:0016020] 0.7824 0.26113 NEVNHAIDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.5878 0 0 0 0 0 0 Q9BTU6 P4K2A_HUMAN Phosphatidylinositol 4-kinase type 2-alpha (EC 2.7.1.67) (Phosphatidylinositol 4-kinase type II-alpha) PI4K2A Homo sapiens (Human) endosome organization [GO:0007032]; Golgi organization [GO:0007030]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol phosphate biosynthetic process [GO:0046854] cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; Golgi membrane [GO:0000139]; growing cell tip [GO:0035838]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; trans-Golgi network [GO:0005802] 1-phosphatidylinositol 4-kinase activity [GO:0004430]; AP-3 adaptor complex binding [GO:0035651]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287] 0.29229 0.82115 IIAVFKPK 0 0 11.4058 0 10.0055 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BTV6 DPH7_HUMAN Diphthine methyltransferase (EC 3.1.1.97) (Diphthamide biosynthesis protein 7) (WD repeat-containing protein 85) DPH7 C9orf112 WDR85 Homo sapiens (Human) peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183] cytoplasm [GO:0005737] diphthine methylesterase activity [GO:0061685] 0.88527 -0.33334 GWDTRVPGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.31655 9.17988 0 0 0 0 0 0 0 Q9BTV7 CABL2_HUMAN CDK5 and ABL1 enzyme substrate 2 (Interactor with CDK3 2) (Ik3-2) CABLES2 C20orf150 Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of cell cycle [GO:0051726] 0.84211 0.14789 SLCAAFSVLPYGEGLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.0126 Q9BTW9 TBCD_HUMAN Tubulin-specific chaperone D (Beta-tubulin cofactor D) (tfcD) (SSD-1) (Tubulin-folding cofactor D) TBCD KIAA0988 SSD1 TFCD PP1096 Homo sapiens (Human) adherens junction assembly [GO:0034333]; bicellular tight junction assembly [GO:0070830]; cell morphogenesis involved in neuron differentiation [GO:0048667]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of microtubule polymerization [GO:0031115]; post-chaperonin tubulin folding pathway [GO:0007023]; protein folding [GO:0006457]; tubulin complex assembly [GO:0007021] adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; lateral plasma membrane [GO:0016328]; microtubule [GO:0005874] beta-tubulin binding [GO:0048487]; GTPase activator activity [GO:0005096]; protein-folding chaperone binding [GO:0051087] 0.95947 -1.8834 GELEKLFPR 0 0 8.22289 0 0 0 0 0 0 0 0 9.36159 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BTX1 NDC1_HUMAN Nucleoporin NDC1 (hNDC1) (Transmembrane protein 48) NDC1 TMEM48 Homo sapiens (Human) homologous chromosome pairing at meiosis [GO:0007129]; mRNA transport [GO:0051028]; nuclear pore complex assembly [GO:0051292]; nuclear pore localization [GO:0051664]; nuclear pore organization [GO:0006999]; nucleocytoplasmic transport [GO:0006913]; protein transport [GO:0015031]; spermatogenesis [GO:0007283] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear pore transmembrane ring [GO:0070762]; plasma membrane [GO:0005886] protein-macromolecule adaptor activity [GO:0030674]; structural constituent of nuclear pore [GO:0017056] 0.81797 0.22023 LILYQEAAATNGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.9646 9.74369 9.84519 0 0 0 0 0 0 Q9BTX7 TTPAL_HUMAN Alpha-tocopherol transfer protein-like TTPAL C20orf121 Homo sapiens (Human) membrane [GO:0016020] phosphatidylinositol bisphosphate binding [GO:1902936] 0.40409 0.69955 ALQLLVNYHSCRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9103 0 0 0 0 0 0 0 0 0 Q9BTY2 FUCO2_HUMAN Plasma alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase 2) (Alpha-L-fucosidase 2) FUCA2 PSEC0151 UNQ227/PRO260 Homo sapiens (Human) fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]; regulation of entry of bacterium into host cell [GO:2000535]; response to bacterium [GO:0009617] azurophil granule lumen [GO:0035578]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764] alpha-L-fucosidase activity [GO:0004560] 0.88354 -0.32378 LSWGYRR 9.11749 0 10.1132 0 0 0 9.30232 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BTZ2 DHRS4_HUMAN Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184) (NADPH-dependent carbonyl reductase) (CR) (NADPH-dependent retinol dehydrogenase/reductase) (NRDR) (humNRDR) (Peroxisomal short-chain alcohol dehydrogenase) (PSCD) (SCAD-SRL) (Short chain dehydrogenase/reductase family 25C member 2) (Protein SDR25C2) (Short-chain dehydrogenase/reductase family member 4) DHRS4 SDR25C2 UNQ851/PRO1800 Homo sapiens (Human) alcohol metabolic process [GO:0006066]; cellular ketone metabolic process [GO:0042180]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; retinal metabolic process [GO:0042574]; steroid metabolic process [GO:0008202] cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777] "3-keto sterol reductase activity [GO:0000253]; 3beta-hydroxy-5beta-steroid dehydrogenase activity [GO:0033703]; alcohol dehydrogenase [NAD(P)+] activity [GO:0018455]; carbonyl reductase (NADPH) activity [GO:0004090]; identical protein binding [GO:0042802]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]" 0.96697 -2.8404 APALMTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.07996 0 9.20408 0 0 0 0 0 0 0 0 0 0 Q9BU40 CRDL1_HUMAN Chordin-like protein 1 (Neuralin-1) (Neurogenesin-1) (Ventroptin) CHRDL1 NRLN1 Homo sapiens (Human) AMPA glutamate receptor clustering [GO:0097113]; BMP signaling pathway [GO:0030509]; cell differentiation [GO:0030154]; embryonic axis specification [GO:0000578]; excitatory chemical synaptic transmission [GO:0098976]; eye development [GO:0001654]; negative regulation of BMP signaling pathway [GO:0030514]; ossification [GO:0001503]; regulation of synaptic plasticity [GO:0048167]; synapse maturation [GO:0060074] endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; synapse [GO:0045202] BMP binding [GO:0036122]; transforming growth factor beta binding [GO:0050431] 0.9529 -1.4692 EARHSYHR 0 0 0 0 0 0 0 0 0 0 9.16159 0 0 0 0 0 0 0 0 8.7788 0 0 0 0 0 0 0 Q9BU61 NDUF3_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 NDUFAF3 C3orf60 Homo sapiens (Human) mitochondrial respiratory chain complex I assembly [GO:0032981] mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634] 0.95968 -1.8248 GHRLSPADDELYQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6287 0 0 0 0 0 0 0 0 0 10.1088 0 Q9BU76 MMTA2_HUMAN Multiple myeloma tumor-associated protein 2 (hMMTAG2) MMTAG2 C1orf35 Homo sapiens (Human) extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774] RNA binding [GO:0003723] 0.95486 -1.6127 AEDQTESSCESHR 0 0 0 0 0 0 0 0 0 0 0 10.4044 0 0 0 0 0 12.5686 0 0 0 0 0 0 0 0 0 Q9BUB4 ADAT1_HUMAN tRNA-specific adenosine deaminase 1 (hADAT1) (EC 3.5.4.34) (tRNA-specific adenosine-37 deaminase) ADAT1 Homo sapiens (Human) tRNA processing [GO:0008033] metal ion binding [GO:0046872]; RNA binding [GO:0003723]; tRNA-specific adenosine deaminase activity [GO:0008251]; tRNA-specific adenosine-37 deaminase activity [GO:0043829] 0.91496 -0.81502 KTIGSLQAR 9.44632 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BUG6 ZSA5A_HUMAN Zinc finger and SCAN domain-containing protein 5A (Zinc finger protein 495) ZSCAN5A ZNF495 ZSCAN5 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.92991 -1.2378 ELQILPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.61554 0 9.69479 0 0 0 0 Q9BUH6 PAXX_HUMAN Protein PAXX (Paralog of XRCC4 and XLF) (XRCC4-like small protein) PAXX C9orf142 XLS Homo sapiens (Human) DNA damage response [GO:0006974]; double-strand break repair via nonhomologous end joining [GO:0006303] cytoplasm [GO:0005737]; nonhomologous end joining complex [GO:0070419]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861] DNA polymerase binding [GO:0070182]; identical protein binding [GO:0042802]; molecular adaptor activity [GO:0060090]; protein homodimerization activity [GO:0042803] 0.8987 -0.6432 FVCYCEGEESGEGDR 10.4491 9.25727 10.2098 0 0 0 0 0 9.28607 0 0 10.8623 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BUH8 BEGIN_HUMAN Brain-enriched guanylate kinase-associated protein BEGAIN KIAA1446 Homo sapiens (Human) regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] cytoplasm [GO:0005737]; membrane [GO:0016020]; synapse [GO:0045202] 0.87681 -0.00056339 LEKLETEFDSTR 0 10.3222 0 0 9.31667 0 0 10.4913 0 0 0 0 0 0 0 0 0 0 0 0 0 9.2963 0 0 0 0 9.51408 Q9BUI4 RPC3_HUMAN DNA-directed RNA polymerase III subunit RPC3 (RNA polymerase III subunit C3) (DNA-directed RNA polymerase III subunit C) (RNA polymerase III 62 kDa subunit) (RPC62) POLR3C Homo sapiens (Human) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728]; regulation of transcription by RNA polymerase III [GO:0006359]; transcription by RNA polymerase III [GO:0006383] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; RNA polymerase III complex [GO:0005666] DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; single-stranded DNA binding [GO:0003697] 0.82226 0.21704 LTETMEDGKTMDYAEVSNTFVR 10.9167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BUJ2 HNRL1_HUMAN Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5) HNRNPUL1 E1BAP5 HNRPUL1 Homo sapiens (Human) response to virus [GO:0009615]; RNA processing [GO:0006396] nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; synapse [GO:0045202] enzyme binding [GO:0019899]; RNA binding [GO:0003723] 0.89907 -0.65687 GPPGGNR 0 0 0 0 0 13.3112 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.84483 9.04379 0 9.87107 0 0 Q9BUP3 HTAI2_HUMAN Oxidoreductase HTATIP2 (EC 1.1.1.-) (30 kDa HIV-1 TAT-interacting protein) (HIV-1 TAT-interactive protein 2) HTATIP2 CC3 TIP30 Homo sapiens (Human) angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; import into nucleus [GO:0051170]; negative regulation of apoptotic process [GO:0043066]; positive regulation of programmed cell death [GO:0043068]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autophosphorylation [GO:0046777]; regulation of angiogenesis [GO:0045765]; regulation of transcription by RNA polymerase II [GO:0006357] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nucleus [GO:0005634] oxidoreductase activity [GO:0016491]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713] 0.96435 -2.4009 AGAEGFVR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.64589 0 0 0 9.12402 0 0 0 9.65517 8.57641 0 9.24029 0 0 Q9BUQ8 DDX23_HUMAN Probable ATP-dependent RNA helicase DDX23 (EC 3.6.4.13) (100 kDa U5 snRNP-specific protein) (DEAD box protein 23) (PRP28 homolog) (U5-100kD) DDX23 Homo sapiens (Human) "cis assembly of pre-catalytic spliceosome [GO:0000354]; mRNA splicing, via spliceosome [GO:0000398]; R-loop processing [GO:0062176]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]" catalytic step 2 spliceosome [GO:0071013]; chromatin [GO:0000785]; extracellular exosome [GO:0070062]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.96123 -2.5738 DIIGVAETGSGK 0 0 0 0 0 0 0 0 0 0 9.43802 0 0 0 0 0 0 0 0 0 10.079 0 0 0 0 0 0 Q9BUV0 RSRP1_HUMAN Arginine/serine-rich protein 1 RSRP1 C1orf63 HT033 NPD014 Homo sapiens (Human) spliceosomal complex assembly [GO:0000245] nucleus [GO:0005634] 0.88255 -0.10338 AATEEASSRSPKIDQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3781 0 0 0 Q9BUY5 ZN426_HUMAN Zinc finger protein 426 ZNF426 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.55925 0.52457 DFLTLCEK 0 0 0 0 0 0 9.07417 0 0 9.1221 9.05441 0 0 0 0 0 0 0 0 0 9.1733 0 0 0 0 10.0968 10.1709 Q9BUY7 EFC11_HUMAN EF-hand calcium-binding domain-containing protein 11 EFCAB11 C14orf143 Homo sapiens (Human) calcium ion binding [GO:0005509] 0.94023 -1.3106 ACDEDHKGYLSREDFK 0 0 0 0 0 9.68774 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BV36 MELPH_HUMAN Melanophilin (Exophilin-3) (Slp homolog lacking C2 domains a) (SlaC2-a) (Synaptotagmin-like protein 2a) MLPH SLAC2A Homo sapiens (Human) intracellular protein transport [GO:0006886]; melanosome transport [GO:0032402] cortical actin cytoskeleton [GO:0030864]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471] actin binding [GO:0003779]; metal ion binding [GO:0046872]; myosin binding [GO:0017022]; protein-macromolecule adaptor activity [GO:0030674]; small GTPase binding [GO:0031267] 0.86183 0.094582 IGSLEWYYEHVK 11.0664 0 0 0 0 0 0 10.8823 10.9558 0 10.6549 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BV38 WDR18_HUMAN WD repeat-containing protein 18 WDR18 Homo sapiens (Human) DNA-templated DNA replication [GO:0006261]; rRNA processing [GO:0006364] dynein axonemal particle [GO:0120293]; nuclear pre-replicative complex [GO:0005656]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; Rix1 complex [GO:0097344] 0.96393 -2.1063 GGQAGPR 0 0 9.67981 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.82817 0 Q9BV40 VAMP8_HUMAN Vesicle-associated membrane protein 8 (VAMP-8) (Endobrevin) (EDB) VAMP8 Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagosome membrane docking [GO:0016240]; defense response to virus [GO:0051607]; mucus secretion [GO:0070254]; negative regulation of secretion by cell [GO:1903531]; positive regulation of histamine secretion by mast cell [GO:1903595]; protein transport [GO:0015031]; regulation of protein localization to plasma membrane [GO:1903076]; SNARE complex assembly [GO:0035493]; vesicle fusion [GO:0006906]; viral entry into host cell [GO:0046718] azurophil granule membrane [GO:0035577]; clathrin-coated endocytic vesicle membrane [GO:0030669]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; extracellular exosome [GO:0070062]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; mucin granule [GO:0098594]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; secretory granule membrane [GO:0030667]; SNARE complex [GO:0031201]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; vesicle [GO:0031982] chloride channel inhibitor activity [GO:0019869]; SNAP receptor activity [GO:0005484]; syntaxin binding [GO:0019905] 0.87108 0.064811 ILARGENLEHLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.10182 0 0 0 0 0 0 0 0 9.0989 0 0 Q9BV44 THUM3_HUMAN tRNA (guanine(6)-N2)-methyltransferase THUMP3 (EC 2.1.1.256) (THUMP domain-containing protein 3) THUMPD3 Homo sapiens (Human) tRNA methylation [GO:0030488]; tRNA N2-guanine methylation [GO:0002940] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730] tRNA (guanine) methyltransferase activity [GO:0016423]; tRNA (guanine-N2-)-methyltransferase activity [GO:0004809]; tRNA binding [GO:0000049] 0.89055 -0.49316 INASFKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4644 Q9BV57 MTND_HUMAN Acireductone dioxygenase (Acireductone dioxygenase (Fe(2+)-requiring)) (ARD') (Fe-ARD) (EC 1.13.11.54) (Acireductone dioxygenase (Ni(2+)-requiring)) (ARD) (Ni-ARD) (EC 1.13.11.53) (Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1) (MTCBP-1) (Submergence-induced protein-like factor) (Sip-L) ADI1 MTCBP1 HMFT1638 Homo sapiens (Human) L-methionine salvage from methylthioadenosine [GO:0019509]; methionine metabolic process [GO:0006555] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886] acireductone dioxygenase (Ni2+-requiring) activity [GO:0010308]; acireductone dioxygenase [iron(II)-requiring] activity [GO:0010309]; iron ion binding [GO:0005506]; nickel cation binding [GO:0016151]; oxidoreductase activity [GO:0016491] 0.94002 -1.298 VQAWYMDDAPGDPR 0 0 0 0 0 0 9.54772 0 0 0 9.8537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BV73 CP250_HUMAN Centrosome-associated protein CEP250 (250 kDa centrosomal protein) (Cep250) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Centrosomal protein 2) CEP250 CEP2 CNAP1 Homo sapiens (Human) centriole-centriole cohesion [GO:0010457]; cilium assembly [GO:0060271]; detection of light stimulus involved in visual perception [GO:0050908]; mitotic cell cycle [GO:0000278]; non-motile cilium assembly [GO:1905515]; positive regulation of protein localization to centrosome [GO:1904781]; protein localization [GO:0008104]; protein localization to centrosome [GO:0071539]; protein localization to organelle [GO:0033365]; regulation of centriole-centriole cohesion [GO:0030997] centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule organizing center [GO:0005815]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; protein-containing complex [GO:0032991] protein domain specific binding [GO:0019904] 0.96896 -11.796 ALREDVEK 10.1021 10.3316 12.2632 0 0 0 0 0 0 10.879 10.7402 11.5578 0 0 11.4864 0 10.5629 0 10.304 8.67112 0 9.78852 0 0 10.3485 8.99772 8.25955 Q9BV79 MECR_HUMAN "Enoyl-[acyl-carrier-protein] reductase, mitochondrial (EC 1.3.1.104) (2-enoyl thioester reductase) (Nuclear receptor-binding factor 1) (HsNrbf-1) (NRBF-1)" MECR NBRF1 CGI-63 Homo sapiens (Human) fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634] trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166] 0.92599 -1.1824 GFWLSQWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.04963 0 0 0 0 0 0 0 0 0 0 9.7808 Q9BV86 NTM1A_HUMAN "N-terminal Xaa-Pro-Lys N-methyltransferase 1 (EC 2.1.1.244) (Alpha N-terminal protein methyltransferase 1A) (Methyltransferase-like protein 11A) (N-terminal RCC1 methyltransferase) (X-Pro-Lys N-terminal protein methyltransferase 1A) (NTM1A) [Cleaved into: N-terminal Xaa-Pro-Lys N-methyltransferase 1, N-terminally processed]" NTMT1 C9orf32 METTL11A NRMT NRMT1 AD-003 Homo sapiens (Human) chromosome segregation [GO:0007059]; N-terminal peptidyl-alanine methylation [GO:0018011]; N-terminal peptidyl-alanine trimethylation [GO:0018012]; N-terminal peptidyl-glycine methylation [GO:0018013]; N-terminal peptidyl-proline dimethylation [GO:0018016]; N-terminal peptidyl-proline methylation [GO:0035568]; N-terminal peptidyl-serine dimethylation [GO:0035572]; N-terminal peptidyl-serine methylation [GO:0035570]; N-terminal peptidyl-serine trimethylation [GO:0035573]; spindle organization [GO:0007051] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] histone methyltransferase activity [GO:0042054]; N-terminal protein N-methyltransferase activity [GO:0071885]; protein methyltransferase activity [GO:0008276] 0.93238 -1.2769 QFYSKAKTYWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5535 0 Q9BV94 EDEM2_HUMAN ER degradation-enhancing alpha-mannosidase-like protein 2 EDEM2 C20orf31 C20orf49 UNQ573/PRO1135 Homo sapiens (Human) "carbohydrate metabolic process [GO:0005975]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; positive regulation of retrograde protein transport, ER to cytosol [GO:1904154]; response to unfolded protein [GO:0006986]; trimming of first mannose on A branch [GO:0036511]; trimming of second mannose on A branch [GO:0036512]; trimming of terminal mannose on B branch [GO:0036509]; trimming of terminal mannose on C branch [GO:0036510]; ubiquitin-dependent glycoprotein ERAD pathway [GO:0097466]; viral protein processing [GO:0019082]" endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum quality control compartment [GO:0044322]; membrane [GO:0016020] "calcium ion binding [GO:0005509]; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [GO:0004571]" 0.96779 -2.9013 DAVESIEKISK 0 0 0 0 0 0 0 0 0 0 0 0 0 16.1473 0 0 0 0 0 0 0 0 0 0 0 11.6165 0 Q9BVA0 KTNB1_HUMAN Katanin p80 WD40 repeat-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin) KATNB1 Homo sapiens (Human) cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; microtubule depolymerization [GO:0007019]; microtubule severing [GO:0051013]; mitotic chromosome movement towards spindle pole [GO:0007079]; negative regulation of microtubule depolymerization [GO:0007026]; positive regulation of cell death [GO:0010942]; positive regulation of microtubule depolymerization [GO:0031117]; positive regulation of neuron projection development [GO:0010976]; protein targeting [GO:0006605] centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; katanin complex [GO:0008352]; membrane [GO:0016020]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; spindle [GO:0005819]; spindle pole [GO:0000922] ATPase regulator activity [GO:0060590]; dynein complex binding [GO:0070840]; microtubule binding [GO:0008017]; protein heterodimerization activity [GO:0046982] 0.76471 0.28388 ASDFLPAVK 0 0 0 0 0 0 0 10.8721 0 0 0 0 11.5773 0 0 0 0 10.7916 0 0 0 0 0 0 0 0 0 Q9BVA1 TBB2B_HUMAN Tubulin beta-2B chain TUBB2B Homo sapiens (Human) cerebral cortex development [GO:0021987]; embryonic brain development [GO:1990403]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; modulation of chemical synaptic transmission [GO:0050804]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669] cytoplasm [GO:0005737]; intercellular bridge [GO:0045171]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; mitotic spindle [GO:0072686]; nucleus [GO:0005634]; Schaffer collateral - CA1 synapse [GO:0098685] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200] 0 3.9202 AILVDLEPGTMDSVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4624 10.2779 0 10.1803 9.41979 0 0 0 0 0 0 10.891 12.187 Q9BVC3 DCC1_HUMAN Sister chromatid cohesion protein DCC1 (Defective in sister chromatid cohesion protein 1 homolog) DSCC1 DCC1 UNQ9337/PRO34008 Homo sapiens (Human) DNA duplex unwinding [GO:0032508]; DNA replication [GO:0006260]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264]; post-translational protein acetylation [GO:0034421]; regulation of DNA replication [GO:0006275] "chromatin [GO:0000785]; chromosome, centromeric region [GO:0000775]; Ctf18 RFC-like complex [GO:0031390]; nucleoplasm [GO:0005654]" DNA binding [GO:0003677] 0.72869 0.34043 DEQAVLCSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.7501 0 0 0 0 0 0 0 Q9BVC4 LST8_HUMAN Target of rapamycin complex subunit LST8 (TORC subunit LST8) (G protein beta subunit-like) (Gable) (Protein GbetaL) (Mammalian lethal with SEC13 protein 8) (mLST8) MLST8 GBL LST8 Homo sapiens (Human) cellular response to hypoxia [GO:0071456]; cellular response to nutrient levels [GO:0031669]; cellular response to osmotic stress [GO:0071470]; cytoskeleton organization [GO:0007010]; DNA damage response [GO:0006974]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; phosphorylation [GO:0016310]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell growth [GO:0030307]; positive regulation of glycolytic process [GO:0045821]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of pentose-phosphate shunt [GO:1905857]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of TOR signaling [GO:0032008]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of GTPase activity [GO:0043087]; TOR signaling [GO:0031929]; TORC1 signaling [GO:0038202] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; TORC1 complex [GO:0031931]; TORC2 complex [GO:0031932] protein serine/threonine kinase activator activity [GO:0043539] 0.57445 0.47836 MNTSPGTVGSDPVILATAGYDHTVR 0 9.22335 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BVC5 ASHWN_HUMAN Ashwin C2orf49 Homo sapiens (Human) "embryonic morphogenesis [GO:0048598]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]" cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tRNA-splicing ligase complex [GO:0072669] 0.84845 0.15595 IQHVTWP 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.97711 0 0 0 0 0 0 0 0 0 Q9BVC6 TM109_HUMAN Transmembrane protein 109 (Mitsugumin-23) (Mg23) TMEM109 Homo sapiens (Human) cellular response to gamma radiation [GO:0071480]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; negative regulation of cell death [GO:0060548]; negative regulation of programmed cell death [GO:0043069]; regulation of monoatomic ion transmembrane transport [GO:0034765] extracellular exosome [GO:0070062]; nuclear outer membrane [GO:0005640]; sarcoplasmic reticulum membrane [GO:0033017] voltage-gated monoatomic ion channel activity [GO:0005244] 0 6.296 EAPVDVLTQIGR 8.63887 0 0 0 0 0 9.04707 9.26285 0 10.1706 9.85961 9.39819 0 0 0 0 0 0 10.1017 0 9.99845 0 9.70726 0 0 11.0962 0 Q9BVG3 TRI62_HUMAN E3 ubiquitin-protein ligase TRIM62 (EC 2.3.2.27) (Tripartite motif-containing protein 62) TRIM62 Homo sapiens (Human) innate immune response [GO:0045087]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of viral transcription [GO:0032897]; positive regulation of antifungal innate immune response [GO:1905036]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein K27-linked ubiquitination [GO:0044314]; protein ubiquitination [GO:0016567]; regulation of viral entry into host cell [GO:0046596]; viral release from host cell [GO:0019076] cytoplasm [GO:0005737]; cytosol [GO:0005829] identical protein binding [GO:0042802]; transcription coactivator activity [GO:0003713]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.92409 -1.0257 SLRTTIGEAFER 0 0 0 0 0 0 0 0 0 0 9.35713 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BVG4 PBDC1_HUMAN Protein PBDC1 (Polysaccharide biosynthesis domain-containing protein 1) PBDC1 CXorf26 Homo sapiens (Human) 0.94742 -1.3585 EGYNKAVYISVQDKEGEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.45884 0 0 0 0 Q9BVG8 KIFC3_HUMAN Kinesin-like protein KIFC3 KIFC3 Homo sapiens (Human) epithelial cell-cell adhesion [GO:0090136]; Golgi organization [GO:0007030]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017]; visual perception [GO:0007601]; zonula adherens maintenance [GO:0045218] centrosome [GO:0005813]; cytoplasmic vesicle membrane [GO:0030659]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; kinesin complex [GO:0005871]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; zonula adherens [GO:0005915] ATP binding [GO:0005524]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777] 0.76794 0.27797 LAEVELR 0 0 0 0 0 0 0 0 0 0 9.35524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BVH7 SIA7E_HUMAN "Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 (EC 2.4.99.-) (GD1 alpha synthase) (GalNAc alpha-2,6-sialyltransferase V) (ST6GalNAc V) (ST6GalNAcV) (Sialyltransferase 7E) (SIAT7-E)" ST6GALNAC5 SIAT7E Homo sapiens (Human) ganglioside biosynthetic process [GO:0001574]; glycosphingolipid biosynthetic process [GO:0006688]; oligosaccharide biosynthetic process [GO:0009312]; oligosaccharide metabolic process [GO:0009311]; protein glycosylation [GO:0006486] Golgi membrane [GO:0000139] "alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity [GO:0001665]; sialyltransferase activity [GO:0008373]" 0.95206 -1.4468 DVGNRTSLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2353 0 0 0 0 0 0 Q9BVI0 PHF20_HUMAN PHD finger protein 20 (Glioma-expressed antigen 2) (Hepatocellular carcinoma-associated antigen 58) (Novel zinc finger protein) (Transcription factor TZP) PHF20 C20orf104 GLEA2 HCA58 NZF TZP Homo sapiens (Human) chromatin organization [GO:0006325]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of histone H3-K4 methylation [GO:0051571]; regulation of dosage compensation by inactivation of X chromosome [GO:1900095]; regulation of transcription by RNA polymerase II [GO:0006357] cytosol [GO:0005829]; histone acetyltransferase complex [GO:0000123]; MLL1 complex [GO:0071339]; NSL complex [GO:0044545]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.96902 -7.0529 AYYPAVEQK 0 0 0 0 10.8552 9.55013 0 0 0 10.703 10.7433 11.6446 0 9.46076 0 0 0 0 0 0 10.218 0 9.35034 10.0161 11.4106 0 0 Q9BVJ6 UT14A_HUMAN U3 small nucleolar RNA-associated protein 14 homolog A (Antigen NY-CO-16) (Serologically defined colon cancer antigen 16) UTP14A SDCCAG16 Homo sapiens (Human) rRNA processing [GO:0006364] cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040] RNA binding [GO:0003723] 0.96712 -2.352 ALKEFEQLR 8.7075 8.78735 0 0 0 0 0 0 0 8.49625 0 0 9.8435 0 0 0 9.7609 0 0 0 0 0 0 0 0 10.3876 0 Q9BVK2 ALG8_HUMAN "Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase (EC 2.4.1.265) (Asparagine-linked glycosylation protein 8 homolog) (Dol-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichyl alpha-1,3-glucosyltransferase) (Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase)" ALG8 HUSSY-02 Homo sapiens (Human) dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; oligosaccharide-lipid intermediate biosynthetic process [GO:0006490]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279] endoplasmic reticulum membrane [GO:0005789] "alpha-1,3-mannosyltransferase activity [GO:0000033]; dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity [GO:0042283]; dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity [GO:0004583]" 0.085714 1.2246 FLDPNNIPK 0 0 0 0 0 0 8.99529 9.42358 9.35238 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BVK6 TMED9_HUMAN Transmembrane emp24 domain-containing protein 9 (GMP25) (Glycoprotein 25L2) (p24 family protein alpha-2) (p24alpha2) (p25) TMED9 GP25L2 Homo sapiens (Human) COPI coating of Golgi vesicle [GO:0048205]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; positive regulation of organelle organization [GO:0010638] COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; synaptic vesicle [GO:0008021]; trans-Golgi network transport vesicle [GO:0030140]; transport vesicle [GO:0030133] syntaxin binding [GO:0019905] 0.0077121 2.0323 QLVEQVEQIQK 8.54921 0 0 0 0 0 9.26217 0 9.14723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BVL4 SELO_HUMAN "Protein adenylyltransferase SelO, mitochondrial (EC 2.7.7.-) (EC 2.7.7.108) (Selenoprotein O) (SelO)" SELENOO SELO Homo sapiens (Human) protein adenylylation [GO:0018117] chromosome [GO:0005694]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein adenylyltransferase activity [GO:0070733] 0.95913 -1.7093 AGIARELER 0 0 0 0 0 0 8.95341 0 0 0 0 0 0 9.07812 0 0 0 0 0 9.67708 0 0 0 0 0 0 0 Q9BVN2 RUSC1_HUMAN AP-4 complex accessory subunit RUSC1 (New molecule containing SH3 at the carboxy-terminus) (Nesca) (RUN and SH3 domain-containing protein 1) RUSC1 NESCA Homo sapiens (Human) protein polyubiquitination [GO:0000209] cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; Golgi apparatus [GO:0005794]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; nucleus [GO:0005634]; postsynaptic density [GO:0014069] actin binding [GO:0003779] 0.96821 -3.8347 ITDSGSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.61637 0 Q9BVP2 GNL3_HUMAN Guanine nucleotide-binding protein-like 3 (E2-induced gene 3 protein) (Novel nucleolar protein 47) (NNP47) (Nucleolar GTP-binding protein 3) (Nucleostemin) GNL3 E2IG3 NS Homo sapiens (Human) "cell population proliferation [GO:0008283]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of protein localization to chromosome, telomeric region [GO:1904816]; positive regulation of protein sumoylation [GO:0033235]; positive regulation of telomere maintenance [GO:0032206]; regulation of cell population proliferation [GO:0042127]; stem cell division [GO:0017145]; stem cell population maintenance [GO:0019827]" chromosome [GO:0005694]; extracellular space [GO:0005615]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleus [GO:0005634] GTP binding [GO:0005525]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723] 0.95243 -1.4744 DIHEELPKR 0 0 0 0 0 0 0 0 9.07866 0 0 0 0 0 0 0 10.6221 0 0 0 0 0 0 9.24805 0 0 0 Q9BVS4 RIOK2_HUMAN Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2) RIOK2 RIO2 Homo sapiens (Human) cell cycle [GO:0007049]; maturation of SSU-rRNA [GO:0030490]; positive regulation of ribosomal small subunit export from nucleus [GO:2000208]; positive regulation of rRNA processing [GO:2000234]; protein autophosphorylation [GO:0046777]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; ribosomal small subunit biogenesis [GO:0042274] "cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; preribosome, small subunit precursor [GO:0030688]" ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.9304 -1.2334 EFRPFRDEENVGAMNQYRTR 0 0 0 0 0 11.1224 0 0 0 0 0 0 0 9.43221 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BVS5 TR61B_HUMAN "tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial (EC 2.1.1.220) (mRNA methyladenosine-N(1)-methyltransferase) (EC 2.1.1.-)" TRMT61B Homo sapiens (Human) mitochondrial tRNA methylation [GO:0070901]; mRNA methylation [GO:0080009]; protein homooligomerization [GO:0051260] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; tRNA (m1A) methyltransferase complex [GO:0031515] mRNA (adenine-N1-)-methyltransferase activity [GO:0061953]; rRNA (adenine) methyltransferase activity [GO:0016433]; tRNA (adenine-N1-)-methyltransferase activity [GO:0016429] 0.92323 -1.055 NYKHWRDSWK 0 12.8944 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BVV2 FND11_HUMAN Fibronectin type III domain-containing protein 11 FNDC11 C20orf195 Homo sapiens (Human) 0.47331 0.62901 AELDALLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.6711 0 0 0 0 0 0 0 0 0 0 Q9BVV6 TALD3_HUMAN Protein TALPID3 KIAA0586 TALPID3 Homo sapiens (Human) cilium assembly [GO:0060271]; regulation of establishment of protein localization [GO:0070201]; smoothened signaling pathway [GO:0007224] centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; photoreceptor inner segment [GO:0001917] 0.96885 -4.5281 FHADAILSFAK 0 0 0 0 10.516 0 11.5527 0 0 0 0 0 0 0 9.88458 0 0 9.41872 0 0 0 0 0 0 0 0 0 Q9BW19 KIFC1_HUMAN Kinesin-like protein KIFC1 (Kinesin-like protein 2) (Kinesin-related protein HSET) KIFC1 HSET KNSL2 Homo sapiens (Human) cell division [GO:0051301]; microtubule-based movement [GO:0007018]; mitotic metaphase plate congression [GO:0007080]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly [GO:0090307] early endosome [GO:0005769]; kinesin complex [GO:0005871]; membrane [GO:0016020]; microtubule [GO:0005874]; microtubule organizing center [GO:0005815]; mitotic spindle [GO:0072686]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777] 0.54679 0.57141 ITTSHPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.52529 Q9BW30 TPPP3_HUMAN Tubulin polymerization-promoting protein family member 3 (TPPP/p20) TPPP3 CGI-38 Homo sapiens (Human) decidualization [GO:0046697]; embryo implantation [GO:0007566]; microtubule bundle formation [GO:0001578]; microtubule polymerization [GO:0046785]; positive regulation of protein polymerization [GO:0032273] cytoplasm [GO:0005737]; microtubule [GO:0005874] tubulin binding [GO:0015631] 0.89842 -0.59433 AKTGGAVDRLTDTSR 0 0 0 0 0 0 0 0 0 9.65903 0 0 0 0 9.72523 13.8588 14.0276 0 10.4579 0 0 0 0 0 10.6592 0 9.84334 Q9BW71 HIRP3_HUMAN HIRA-interacting protein 3 HIRIP3 Homo sapiens (Human) chromatin organization [GO:0006325] nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.96928 -3.0569 EPPVQRKSEDR 0 0 13.3626 0 0 12.0769 0 0 0 0 9.10573 11.5868 12.4651 0 12.6685 0 0 0 0 0 0 0 0 0 0 0 0 Q9BW85 YJU2_HUMAN Splicing factor YJU2 (Coiled-coil domain-containing protein 94) YJU2 CCDC94 Homo sapiens (Human) "generation of catalytic spliceosome for first transesterification step [GO:0000349]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; RNA splicing [GO:0008380]" nucleoplasm [GO:0005654]; U2-type catalytic step 1 spliceosome [GO:0071006] metal ion binding [GO:0046872] 0.94118 -1.3148 LSEEERRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3136 0 0 Q9BW91 NUDT9_HUMAN "ADP-ribose pyrophosphatase, mitochondrial (EC 3.6.1.13) (ADP-ribose diphosphatase) (ADP-ribose phosphohydrolase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (Nucleoside diphosphate-linked moiety X motif 9) (Nudix motif 9)" NUDT9 NUDT10 PSEC0099 UNQ3012/PRO9771 Homo sapiens (Human) ADP catabolic process [GO:0046032]; IDP catabolic process [GO:0046709]; nucleobase-containing small molecule metabolic process [GO:0055086] cell junction [GO:0030054]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965] ADP-ribose diphosphatase activity [GO:0047631]; ADP-sugar diphosphatase activity [GO:0019144] 0.95741 -1.6522 ARTSPYPGSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.81556 0 9.6789 0 0 9.3959 0 0 0 0 Q9BW92 SYTM_HUMAN "Threonine--tRNA ligase, mitochondrial (EC 6.1.1.3) (Threonyl-tRNA synthetase) (ThrRS) (Threonyl-tRNA synthetase-like 1)" TARS2 TARSL1 Homo sapiens (Human) mitochondrial threonyl-tRNA aminoacylation [GO:0070159]; threonyl-tRNA aminoacylation [GO:0006435] mitochondrial matrix [GO:0005759] aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; threonine-tRNA ligase activity [GO:0004829] 0.96319 -2.1577 IDAVAWNTTPYQLAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.4103 0 0 0 0 0 0 0 0 0 9.89508 0 0 Q9BWD1 THIC_HUMAN "Acetyl-CoA acetyltransferase, cytosolic (EC 2.3.1.9) (Acetyl-CoA transferase-like protein) (Cytosolic acetoacetyl-CoA thiolase)" ACAT2 ACTL Homo sapiens (Human) fatty acid beta-oxidation [GO:0006635]; lipid metabolic process [GO:0006629] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739] acetyl-CoA C-acetyltransferase activity [GO:0003985] 0 19.127 ELGLNPEK 0 8.47808 0 0 9.98783 0 9.09879 9.01959 9.0545 9.03133 9.7151 9.20692 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BWE0 REPI1_HUMAN Replication initiator 1 (60 kDa origin-specific DNA-binding protein) (60 kDa replication initiation region protein) (ATT-binding protein) (DHFR oribeta-binding protein RIP60) (Zinc finger protein 464) REPIN1 RIP60 ZNF464 Homo sapiens (Human) DNA replication [GO:0006260]; regulation of transcription by RNA polymerase II [GO:0006357] chromosome [GO:0005694]; nuclear origin of replication recognition complex [GO:0005664]; nucleoplasm [GO:0005654] chromatin insulator sequence binding [GO:0043035]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; RNA binding [GO:0003723] 0.8967 -0.67467 IHTGEKPYPCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4553 0 10.684 0 0 0 0 0 0 0 0 0 0 Q9BWF2 TRAIP_HUMAN E3 ubiquitin-protein ligase TRAIP (EC 2.3.2.27) (RING finger protein 206) (TRAF-interacting protein) TRAIP RNF206 TRIP Homo sapiens (Human) apoptotic process [GO:0006915]; DNA damage response [GO:0006974]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; protein ubiquitination [GO:0016567]; protein-DNA covalent cross-linking repair [GO:0106300]; replication fork processing [GO:0031297]; signal transduction [GO:0007165] nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; site of DNA damage [GO:0090734] identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.95955 -1.7161 DLFSSRSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.40546 0 0 0 0 0 0 0 0 Q9BWG4 SSBP4_HUMAN Single-stranded DNA-binding protein 4 SSBP4 Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944] nucleus [GO:0005634] single-stranded DNA binding [GO:0003697] 0.82241 0.21586 EACEHSGEAK 0 0 9.27519 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BWH2 FUND2_HUMAN FUN14 domain-containing protein 2 (Cervical cancer proto-oncogene 3 protein) (HCC-3) (Hepatitis C virus core-binding protein 6) FUNDC2 HCBP6 DC44 HCC3 PD03104 Homo sapiens (Human) autophagy of mitochondrion [GO:0000422]; intracellular triglyceride homeostasis [GO:0035356]; regulation of platelet activation [GO:0010543] mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleus [GO:0005634] "phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]" 0.9161 -0.809 AEEVVSFVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.89294 0 0 0 0 0 0 0 0 0 10.6774 0 0 Q9BWH6 RPAP1_HUMAN RNA polymerase II-associated protein 1 RPAP1 KIAA1403 Homo sapiens (Human) transcription by RNA polymerase II [GO:0006366] DNA-directed RNA polymerase complex [GO:0000428]; nucleus [GO:0005634] DNA binding [GO:0003677]; nucleotidyltransferase activity [GO:0016779] 0.8904 -0.46337 DTQGKSATSGKR 15.4394 15.5183 14.8231 10.5998 10.5732 10.5787 14.9356 15.3542 15.4108 15.2331 15.2542 15.3654 10.108 11.0831 10.0713 10.1587 10.0782 10.0297 0 0 0 0 0 0 0 0 0 Q9BWM5 ZN416_HUMAN Zinc finger protein 416 ZNF416 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.94051 -1.3313 LYESSKCGK 9.38241 0 0 0 9.53995 9.20962 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BWS9 CHID1_HUMAN Chitinase domain-containing protein 1 (Stabilin-1-interacting chitinase-like protein) (SI-CLP) CHID1 GL008 PSEC0104 SB139 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; innate immune response [GO:0045087]; negative regulation of cytokine production involved in inflammatory response [GO:1900016] endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; membrane [GO:0016020]; nucleus [GO:0005634]; trans-Golgi network [GO:0005802] chitin binding [GO:0008061]; oligosaccharide binding [GO:0070492] 0.84926 0.1123 DHRPRMVWDSQASEHFFEYKK 0 0 0 0 0 0 9.81737 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BWT1 CDCA7_HUMAN Cell division cycle-associated protein 7 (Protein JPO1) CDCA7 JPO1 Homo sapiens (Human) apoptotic process [GO:0006915]; regulation of cell population proliferation [GO:0042127]; regulation of DNA-templated transcription [GO:0006355] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.96776 -2.9347 SLGSTCHQCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.72644 0 Q9BWT3 PAPOG_HUMAN Poly(A) polymerase gamma (PAP-gamma) (EC 2.7.7.19) (Neo-poly(A) polymerase) (Neo-PAP) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3'-adenylating enzyme) (Signal recognition particle RNA-adenylating enzyme) (SRP RNA-adenylating enzyme) PAPOLG PAP2 PAPG Homo sapiens (Human) mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631] cytosol [GO:0005829]; membrane [GO:0016020]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; poly(A) RNA polymerase activity [GO:1990817]; RNA binding [GO:0003723] 0.96338 -2.1213 DDSRLRSLDIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1165 10.6035 0 0 0 10.8116 Q9BWT7 CAR10_HUMAN Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3) CARD10 CARMA3 Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; positive regulation of protein localization to nucleus [GO:1900182]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981] CBM complex [GO:0032449]; cytoplasm [GO:0005737] signaling receptor complex adaptor activity [GO:0030159] 0.96867 -3.9269 DQAIQSR 0 0 0 0 0 0 0 0 0 0 12.4092 0 0 0 0 0 0 9.96203 0 8.30702 0 0 0 0 0 0 0 Q9BWU0 NADAP_HUMAN Kanadaptin (Human lung cancer oncogene 3 protein) (HLC-3) (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein) SLC4A1AP HLC3 Homo sapiens (Human) cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] mRNA binding [GO:0003729] 0.78641 0.25478 LPVDDSTGK 0 10.2267 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BWU1 CDK19_HUMAN Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell division cycle 2-like protein kinase 6) (Cell division protein kinase 19) (Cyclin-dependent kinase 11) (Death-preventing kinase) CDK19 CDC2L6 CDK11 KIAA1028 Homo sapiens (Human) cellular response to lipopolysaccharide [GO:0071222]; positive regulation of apoptotic process [GO:0043065]; positive regulation of inflammatory response [GO:0050729]; protein phosphorylation [GO:0006468] cytosol [GO:0005829]; mediator complex [GO:0016592]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] ATP binding [GO:0005524]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein serine kinase activity [GO:0106310] 0.9598 -1.9255 LLTMDPTK 0 0 0 0 0 0 0 0 0 0 9.23695 0 0 0 9.11964 0 0 0 0 0 0 0 0 0 0 0 0 Q9BWV3 CDAC1_HUMAN Cytidine and dCMP deaminase domain-containing protein 1 (EC 3.5.4.5) (Cytidine deaminase) (Testis development protein NYD-SP15) CDADC1 Homo sapiens (Human) cytidine deamination [GO:0009972]; DNA cytosine deamination [GO:0070383] cytoplasm [GO:0005737]; nucleus [GO:0005634] cytidine deaminase activity [GO:0004126]; importin-alpha family protein binding [GO:0061676]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270] 0.92368 -1.02 EAGQMQNLESAR 0 0 9.0802 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BWW7 SCRT1_HUMAN Transcriptional repressor scratch 1 (Scratch homolog 1 zinc finger protein) (SCRT) (Scratch 1) (hScrt) SCRT1 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355]; regulation of neuron migration [GO:2001222] nuclear body [GO:0016604] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96904 -3.9011 GYLSDYVGPSSVYDGDAEAALLK 0 0 0 0 0 11.6964 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2482 10.9562 10.2501 10.2589 0 0 0 0 Q9BWW8 APOL6_HUMAN Apolipoprotein L6 (Apolipoprotein L-VI) (ApoL-VI) APOL6 UNQ3095/PRO21341 Homo sapiens (Human) lipid transport [GO:0006869]; lipoprotein metabolic process [GO:0042157] cytoplasm [GO:0005737]; extracellular region [GO:0005576] lipid binding [GO:0008289] 0.96369 -2.2307 EDLKGNIDK 0 0 0 0 0 10.2232 0 0 0 8.90057 0 10.9553 0 10.7511 10.6589 0 0 0 0 0 0 0 0 0 0 0 0 Q9BWW9 APOL5_HUMAN Apolipoprotein L5 (Apolipoprotein L-V) (ApoL-V) APOL5 Homo sapiens (Human) lipid metabolic process [GO:0006629]; lipid transport [GO:0006869]; lipoprotein metabolic process [GO:0042157] cytoplasm [GO:0005737]; extracellular region [GO:0005576] high-density lipoprotein particle binding [GO:0008035]; lipid binding [GO:0008289] 0.95085 -1.406 HIPFWTAR 0 0 0 0 0 8.33307 0 0 0 0 0 0 0 0 0 0 0 0 10.2239 9.92967 9.76759 0 0 0 0 0 0 Q9BWX1 PHF7_HUMAN PHD finger protein 7 (Testis development protein NYD-SP6) PHF7 Homo sapiens (Human) cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] metal ion binding [GO:0046872] 0.96865 -3.9125 EPGDPEK 0 0 0 0 0 0 0 0 0 0 0 9.12521 0 0 0 0 0 0 0 0 0 8.42017 8.51199 0 0 0 0 Q9BX10 GTPB2_HUMAN GTP-binding protein 2 GTPBP2 Homo sapiens (Human) translational elongation [GO:0006414] extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; translation elongation factor activity [GO:0003746] 0.95914 -1.876 FLKHPEYLK 0 0 0 0 0 9.74403 0 0 0 0 0 0 0 0 0 0 0 0 9.43979 8.911 0 0 9.77803 9.81319 0 0 0 Q9BX26 SYCP2_HUMAN Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2) SYCP2 SCP2 Homo sapiens (Human) apoptotic process [GO:0006915]; cell division [GO:0051301]; ectopic germ cell programmed cell death [GO:0035234]; female meiotic nuclear division [GO:0007143]; fertilization [GO:0009566]; male genitalia morphogenesis [GO:0048808]; male meiotic nuclear division [GO:0007140]; negative regulation of apoptotic process [GO:0043066]; negative regulation of developmental process [GO:0051093]; negative regulation of reproductive process [GO:2000242]; synaptonemal complex assembly [GO:0007130] lateral element [GO:0000800]; nucleus [GO:0005634]; synaptonemal complex [GO:0000795] DNA binding [GO:0003677] 0.96835 -9.4715 EDMKVLQDR 0 0 10.0157 0 10.8011 0 0 10.2685 0 10.0207 0 0 10.4308 0 0 0 0 0 0 0 10.5469 0 0 0 0 0 9.70442 Q9BX40 LS14B_HUMAN Protein LSM14 homolog B (RNA-associated protein 55B) (hRAP55B) LSM14B C20orf40 FAM61B RAP55B Homo sapiens (Human) regulation of translation [GO:0006417] ribonucleoprotein complex [GO:1990904] mRNA binding [GO:0003729]; RNA binding [GO:0003723] 0.91391 -0.7849 LNFKDDK 0 0 0 0 0 0 0 0 0 0 0 0 8.26238 0 0 0 0 0 0 0 0 9.5504 0 0 9.84131 0 0 Q9BX63 FANCJ_HUMAN Fanconi anemia group J protein (Protein FACJ) (EC 3.6.4.13) (ATP-dependent RNA helicase BRIP1) (BRCA1-associated C-terminal helicase 1) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) BRIP1 BACH1 FANCJ Homo sapiens (Human) cellular response to angiotensin [GO:1904385]; cellular response to hypoxia [GO:0071456]; cellular response to vitamin [GO:0071295]; chiasma assembly [GO:0051026]; DNA damage checkpoint signaling [GO:0000077]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair involved in meiotic recombination [GO:1990918]; homologous recombination [GO:0035825]; meiotic DNA double-strand break processing involved in reciprocal meiotic recombination [GO:0010705]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; nucleotide-excision repair [GO:0006289]; regulation of transcription by RNA polymerase II [GO:0006357]; response to toxic substance [GO:0009636]; seminiferous tubule development [GO:0072520]; spermatid development [GO:0007286]; spermatogonial cell division [GO:0007284] BRCA1-B complex [GO:0070532]; cytoplasm [GO:0005737]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "4 iron, 4 sulfur cluster binding [GO:0051539]; 5'-3' DNA helicase activity [GO:0043139]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; metal ion binding [GO:0046872]; RNA helicase activity [GO:0003724]" 0.96966 -5.9211 AEKIVISRSTSPTFNK 8.74335 0 0 9.81219 9.84721 9.93764 9.60125 0 9.31651 0 0 0 9.23467 0 0 0 0 0 11.8583 0 0 0 0 0 0 10.2943 0 Q9BX66 SRBS1_HUMAN Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP) SORBS1 KIAA0894 KIAA1296 SH3D5 Homo sapiens (Human) cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; cellular response to insulin stimulus [GO:0032869]; focal adhesion assembly [GO:0048041]; insulin receptor signaling pathway [GO:0008286]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of protein localization to plasma membrane [GO:1903078]; stress fiber assembly [GO:0043149] adherens junction [GO:0005912]; cell-substrate junction [GO:0030055]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; flotillin complex [GO:0016600]; focal adhesion [GO:0005925]; membrane raft [GO:0045121]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; zonula adherens [GO:0005915] actin binding [GO:0003779]; cytoskeletal protein binding [GO:0008092]; insulin receptor binding [GO:0005158]; signaling receptor complex adaptor activity [GO:0030159] 0.92256 -1.0586 ATADPLR 9.63016 0 0 0 0 0 0 0 0 0 0 0 0 9.96751 0 0 0 0 0 0 0 10.603 0 0 0 0 0 Q9BX67 JAM3_HUMAN Junctional adhesion molecule C (JAM-C) (JAM-2) (Junctional adhesion molecule 3) (JAM-3) [Cleaved into: Soluble form of JAM-C (sJAM-C)] JAM3 UNQ859/PRO1868 Homo sapiens (Human) adaptive immune response [GO:0002250]; adherens junction assembly [GO:0034333]; angiogenesis [GO:0001525]; apical protein localization [GO:0045176]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; establishment of cell polarity [GO:0030010]; granulocyte migration [GO:0097530]; hematopoietic stem cell migration to bone marrow [GO:0097241]; heterotypic cell-cell adhesion [GO:0034113]; leukocyte migration involved in inflammatory response [GO:0002523]; maintenance of blood-brain barrier [GO:0035633]; myelination [GO:0042552]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of integrin activation [GO:0033624]; neutrophil homeostasis [GO:0001780]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of membrane permeability [GO:1905710]; protein localization to cell junction [GO:1902414]; protein localization to cell surface [GO:0034394]; regulation of actin cytoskeleton organization by cell-cell adhesion [GO:0090138]; regulation of neutrophil chemotaxis [GO:0090022]; spermatid development [GO:0007286]; transmission of nerve impulse [GO:0019226] bicellular tight junction [GO:0005923]; cell-cell contact zone [GO:0044291]; cell-cell junction [GO:0005911]; desmosome [GO:0030057]; extracellular space [GO:0005615]; filamentous actin [GO:0031941]; Golgi apparatus [GO:0005794]; microvillus [GO:0005902]; paranodal junction [GO:0033010]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]; Schmidt-Lanterman incisure [GO:0043220]; tight junction [GO:0070160] cell-cell adhesion mediator activity [GO:0098632]; integrin binding [GO:0005178]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803] 0.91373 -0.80184 NDVPLPTDSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6304 0 0 0 Q9BX68 HINT2_HUMAN "Adenosine 5'-monophosphoramidase HINT2 (EC 3.9.1.-) (HINT-3) (HIT-17kDa) (Histidine triad nucleotide-binding protein 2, mitochondrial) (HINT-2) (PKCI-1-related HIT protein)" HINT2 Homo sapiens (Human) apoptotic process [GO:0006915]; lipid catabolic process [GO:0016042]; negative regulation of peptidyl-lysine acetylation [GO:2000757]; steroid biosynthetic process [GO:0006694] cytoplasm [GO:0005737]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739] adenosine 5'-monophosphoramidase activity [GO:0043530]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166] 0.80201 0.23984 AEGLGDGYR 9.22887 8.90746 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.10019 0 0 0 0 Q9BX84 TRPM6_HUMAN Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6) TRPM6 CHAK2 Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; monoatomic cation transmembrane transport [GO:0098655]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; response to toxic substance [GO:0009636] apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; calcium channel activity [GO:0005262]; metal ion binding [GO:0046872]; monoatomic cation channel activity [GO:0005261]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.61381 0.42226 GVFDKRECSTIIPSSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3388 0 0 0 0 0 9.74012 0 0 8.9924 Q9BX97 PLVAP_HUMAN Plasmalemma vesicle-associated protein (Fenestrated endothelial-linked structure protein) (Plasmalemma vesicle protein 1) (PV-1) PLVAP FELS PV1 Homo sapiens (Human) developmental process [GO:0032502]; MAPK cascade [GO:0000165]; positive regulation of cellular extravasation [GO:0002693]; regulation of vascular permeability [GO:0043114]; tumor necrosis factor-mediated signaling pathway [GO:0033209] caveola [GO:0005901]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471] identical protein binding [GO:0042802] 0.95191 -1.3956 EKTICTKDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.1629 9.10614 0 0 0 0 10.2071 0 10.2596 0 0 0 0 Q9BXA9 SALL3_HUMAN Sal-like protein 3 (Zinc finger protein 796) (Zinc finger protein SALL3) (hSALL3) SALL3 ZNF796 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.82523 0.2147 MTDPNQCVICHR 0 0 0 0 0 0 0 0 0 0 0 0 9.64488 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BXB1 LGR4_HUMAN Leucine-rich repeat-containing G-protein coupled receptor 4 (G-protein coupled receptor 48) LGR4 GPR48 Homo sapiens (Human) bone mineralization [GO:0030282]; bone remodeling [GO:0046849]; canonical Wnt signaling pathway involved in metanephric kidney development [GO:0061290]; cell differentiation involved in metanephros development [GO:0072202]; circadian regulation of gene expression [GO:0032922]; digestive tract development [GO:0048565]; epithelial cell proliferation involved in renal tubule morphogenesis [GO:2001013]; hair follicle development [GO:0001942]; innate immune response [GO:0045087]; intestinal stem cell homeostasis [GO:0036335]; male genitalia development [GO:0030539]; metanephric glomerulus development [GO:0072224]; metanephric nephron tubule morphogenesis [GO:0072282]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of cytokine production [GO:0001818]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; osteoblast differentiation [GO:0001649]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of DNA-templated transcription [GO:0045893]; spermatogenesis [GO:0007283] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; protein-hormone receptor activity [GO:0016500]; transmembrane signaling receptor activity [GO:0004888] 0.6137 0.42346 ISSIPNNLCQEQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0564 0 9.27079 0 0 0 0 0 0 0 Q9BXB4 OSB11_HUMAN Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11) OSBPL11 ORP11 OSBP12 Homo sapiens (Human) fat cell differentiation [GO:0045444]; positive regulation of sequestering of triglyceride [GO:0010890] cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; membrane [GO:0016020]; nucleoplasm [GO:0005654] sterol binding [GO:0032934]; sterol transporter activity [GO:0015248] 0.61413 0.42367 IIPTTQPAE 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.72935 0 0 0 9.78658 0 Q9BXB7 SPT16_HUMAN Spermatogenesis-associated protein 16 (Testis development protein NYD-SP12) SPATA16 Homo sapiens (Human) spermatid development [GO:0007286]; spermatogenesis [GO:0007283] acrosomal vesicle [GO:0001669]; Golgi apparatus [GO:0005794] 0.88957 -0.42254 AEGEEKPTRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.67163 9.83648 Q9BXC9 BBS2_HUMAN Bardet-Biedl syndrome 2 protein BBS2 Homo sapiens (Human) adult behavior [GO:0030534]; artery smooth muscle contraction [GO:0014824]; brain morphogenesis [GO:0048854]; cartilage development [GO:0051216]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; fat cell differentiation [GO:0045444]; gene expression [GO:0010467]; Golgi to plasma membrane protein transport [GO:0043001]; hippocampus development [GO:0021766]; melanosome transport [GO:0032402]; negative regulation of appetite by leptin-mediated signaling pathway [GO:0038108]; negative regulation of gene expression [GO:0010629]; negative regulation of multicellular organism growth [GO:0040015]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of multicellular organism growth [GO:0040018]; protein localization [GO:0008104]; protein localization to organelle [GO:0033365]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296]; sperm axoneme assembly [GO:0007288]; striatum development [GO:0021756]; vasodilation [GO:0042311]; visual perception [GO:0007601] BBSome [GO:0034464]; ciliary basal body [GO:0036064]; ciliary membrane [GO:0060170]; cytosol [GO:0005829]; membrane [GO:0016020]; microvillus [GO:0005902]; motile cilium [GO:0031514]; neuron projection [GO:0043005]; stereocilium [GO:0032420] RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629] 0.76997 0.26924 ISTSNDTIIR 0 0 0 0 0 0 0 0 10.8117 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BXF3 CECR2_HUMAN Chromatin remodeling regulator CECR2 (Cat eye syndrome critical region protein 2) CECR2 KIAA1740 Homo sapiens (Human) apoptotic DNA fragmentation [GO:0006309]; chromatin remodeling [GO:0006338]; cochlea development [GO:0090102]; cytoskeleton organization [GO:0007010]; cytoskeleton-dependent cytokinesis [GO:0061640]; execution phase of apoptosis [GO:0097194]; inner ear receptor cell stereocilium organization [GO:0060122]; neural fold formation [GO:0001842]; neural tube closure [GO:0001843]; single fertilization [GO:0007338]; vesicle-mediated transport [GO:0016192] CERF complex [GO:0090537]; euchromatin [GO:0000791]; nucleus [GO:0005634] ATP-dependent chromatin remodeler activity [GO:0140658] 0.9692 -4.5665 EFLDLDNHNAATK 0 0 0 0 0 0 0 9.03988 11.892 0 0 0 0 9.09247 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BXF6 RFIP5_HUMAN Rab11 family-interacting protein 5 (Rab11-FIP5) (Gamma-SNAP-associated factor 1) (Gaf-1) (Phosphoprotein pp75) (Rab11-interacting protein Rip11) RAB11FIP5 GAF1 KIAA0857 RIP11 Homo sapiens (Human) cellular response to acidic pH [GO:0071468]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; negative regulation of adiponectin secretion [GO:0070164]; regulated exocytosis [GO:0045055]; regulation of protein localization to cell surface [GO:2000008] centriolar satellite [GO:0034451]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; phagocytic vesicle [GO:0045335]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; secretory granule [GO:0030141]; transport vesicle membrane [GO:0030658] gamma-tubulin binding [GO:0043015]; small GTPase binding [GO:0031267] 0.86942 0.044858 NNLSASMFDLSMK 0 0 0 0 8.79568 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BXF9 TEKT3_HUMAN Tektin-3 TEKT3 Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement involved in cell motility [GO:0060294]; flagellated sperm motility [GO:0030317]; regulation of brood size [GO:0060378] acrosomal membrane [GO:0002080]; axonemal microtubule [GO:0005879]; extracellular exosome [GO:0070062]; microtubule cytoskeleton [GO:0015630]; nucleus [GO:0005634]; outer acrosomal membrane [GO:0002081]; sperm flagellum [GO:0036126] 0.78622 0.25829 FTDDNILR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8045 Q9BXG8 SPZ1_HUMAN Spermatogenic leucine zipper protein 1 (Testis-specific protein 1) (Testis-specific protein NYD-TSP1) SPZ1 TSP1 Homo sapiens (Human) cytoplasm [GO:0005737]; nucleus [GO:0005634] DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700] 0.60951 0.43141 VEMYKQNK 0 0 0 0 0 0 0 10.9812 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BXH1 BBC3_HUMAN "Bcl-2-binding component 3, isoforms 1/2 (JFY-1) (p53 up-regulated modulator of apoptosis)" BBC3 PUMA Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic signaling pathway [GO:0097190]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; determination of adult lifespan [GO:0008340]; DNA damage response [GO:0006974]; execution phase of apoptosis [GO:0097194]; fibroblast apoptotic process [GO:0044346]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; negative regulation of growth [GO:0045926]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein homooligomerization [GO:0032464]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein-containing complex assembly [GO:0031334]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of thymocyte apoptotic process [GO:0070245]; protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:0001844]; release of cytochrome c from mitochondria [GO:0001836]; release of sequestered calcium ion into cytosol [GO:0051209]; response to endoplasmic reticulum stress [GO:0034976]; T cell apoptotic process [GO:0070231]; toxin transport [GO:1901998] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; PUMA-BCL-xl complex [GO:0097143] 0.96176 -2.5603 APEMEPN 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.86009 0 0 0 0 0 0 0 Q9BXJ2 C1QT7_HUMAN Complement C1q tumor necrosis factor-related protein 7 C1QTNF7 CTRP7 Homo sapiens (Human) collagen trimer [GO:0005581]; extracellular region [GO:0005576] 0.94581 -1.343 GDQGETGKKGPIGPEGEK 0 0 0 0 0 0 0 0 0 0 9.76384 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BXJ3 C1QT4_HUMAN Complement C1q tumor necrosis factor-related protein 4 (C1q/TNF-related protein 4) C1QTNF4 CTRP4 Homo sapiens (Human) positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6-mediated signaling pathway [GO:0070105]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of tumor necrosis factor production [GO:0032760] extracellular space [GO:0005615] cytokine activity [GO:0005125] 0.84869 0.15615 YITFSGFLVYPDLAPAAPPGLGASELL 13.3106 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BXJ5 C1QT2_HUMAN Complement C1q tumor necrosis factor-related protein 2 C1QTNF2 CTRP2 UNQ6349/PRO21054 Homo sapiens (Human) regulation of lipid metabolic process [GO:0019216] collagen trimer [GO:0005581]; extracellular region [GO:0005576] 0.92005 -1.1426 AGPRGPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.78836 0 0 Q9BXJ7 AMNLS_HUMAN Protein amnionless [Cleaved into: Soluble protein amnionless] AMN UNQ513/PRO1028 Homo sapiens (Human) cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; Golgi to plasma membrane protein transport [GO:0043001]; protein localization [GO:0008104]; receptor-mediated endocytosis [GO:0006898]; renal protein absorption [GO:0097017] apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; clathrin-coated pit [GO:0005905]; endocytic vesicle [GO:0030139]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] cargo receptor activity [GO:0038024]; signaling receptor binding [GO:0005102] 0.88346 -0.057446 HDDVFFPPSASFR 0 8.89636 0 0 0 0 9.40848 0 10.8022 9.46418 0 9.34578 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BXJ8 TACAN_HUMAN Ion channel TACAN (Transmembrane protein 120A) (Transmembrane protein induced by tumor necrosis factor alpha) TMEM120A TACAN TMPIT Homo sapiens (Human) detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; fat cell differentiation [GO:0045444]; monoatomic ion transmembrane transport [GO:0034220]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260] membrane [GO:0016020]; nuclear inner membrane [GO:0005637]; plasma membrane [GO:0005886] monoatomic ion channel activity [GO:0005216] 0.8699 0.057541 LQNNCTSSITR 0 0 0 0 0 0 0 9.24105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BXJ9 NAA15_HUMAN "N-alpha-acetyltransferase 15, NatA auxiliary subunit (Gastric cancer antigen Ga19) (N-terminal acetyltransferase) (NMDA receptor-regulated protein 1) (Protein tubedown-1) (Tbdn100)" NAA15 GA19 NARG1 NATH TBDN100 Homo sapiens (Human) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; N-terminal peptidyl-methionine acetylation [GO:0017196]; N-terminal protein amino acid acetylation [GO:0006474]; negative regulation of apoptotic process [GO:0043066]; positive regulation of DNA-templated transcription [GO:0045893]; protein stabilization [GO:0050821] cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; NatA complex [GO:0031415]; nuclear body [GO:0016604]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] ribosome binding [GO:0043022]; RNA binding [GO:0003723] 0.95923 -1.7091 LEDAADVYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.185 0 10.9625 0 0 0 0 Q9BXK1 KLF16_HUMAN Krueppel-like factor 16 (Basic transcription element-binding protein 4) (BTE-binding protein 4) (Novel Sp1-like zinc finger transcription factor 2) (Transcription factor BTEB4) (Transcription factor NSLP2) KLF16 BTEB4 NSLP2 Homo sapiens (Human) dopamine receptor signaling pathway [GO:0007212]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.93339 -1.2795 FSCPLCSKRFTR 0 0 0 0 0 8.74322 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BXL5 HEMGN_HUMAN Hemogen (Erythroid differentiation-associated gene protein) (EDAG-1) (Hemopoietic gene protein) (Negative differentiation regulator protein) HEMGN EDAG NDR PRO1037 PRO1620 Homo sapiens (Human) cell differentiation [GO:0030154]; regulation of osteoblast differentiation [GO:0045667] nucleoplasm [GO:0005654] 0.84844 0.15439 ALAPIEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.28529 0 0 0 0 0 0 0 0 0 0 Q9BXL6 CAR14_HUMAN Caspase recruitment domain-containing protein 14 (CARD-containing MAGUK protein 2) (Carma 2) CARD14 CARMA2 Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein phosphorylation [GO:0001934]; tumor necrosis factor-mediated signaling pathway [GO:0033209] aggresome [GO:0016235]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886] CARD domain binding [GO:0050700] 0.88404 -0.12246 AGHLLDLLK 0 0 0 0 0 0 0 8.58538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.64308 0 8.98265 0 Q9BXL7 CAR11_HUMAN Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 1) (Carma 1) CARD11 CARMA1 Homo sapiens (Human) "B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; CD4-positive, alpha-beta T cell proliferation [GO:0035739]; homeostasis of number of cells [GO:0048872]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell receptor signaling pathway [GO:0050862]; protein homooligomerization [GO:0051260]; regulation of apoptotic process [GO:0042981]; regulation of B cell differentiation [GO:0045577]; regulation of T cell differentiation [GO:0045580]; T cell costimulation [GO:0031295]; thymic T cell selection [GO:0045061]; TORC1 signaling [GO:0038202]" CBM complex [GO:0032449]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; immunological synapse [GO:0001772]; membrane raft [GO:0045121]; plasma membrane [GO:0005886] CARD domain binding [GO:0050700]; guanylate kinase activity [GO:0004385]; protein self-association [GO:0043621] 0.96934 -3.467 CSTLGKDCEMYK 11.8882 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4343 0 0 0 0 0 0 8.80529 9.72799 0 0 0 0 Q9BXM0 PRAX_HUMAN Periaxin PRX KIAA1620 Homo sapiens (Human) axon ensheathment [GO:0008366]; peripheral nervous system myelin maintenance [GO:0032287]; regulation of RNA splicing [GO:0043484] anchoring junction [GO:0070161]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886] 0.95447 -1.5239 APEVQLKATK 0 0 0 0 0 0 0 0 0 0 11.1081 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BXM7 PINK1_HUMAN "Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)" PINK1 Homo sapiens (Human) "activation of protein kinase B activity [GO:0032148]; autophagy of mitochondrion [GO:0000422]; cellular response to hydrogen sulfide [GO:1904881]; cellular response to hypoxia [GO:0071456]; cellular response to oxidative stress [GO:0034599]; cellular response to toxic substance [GO:0097237]; dopamine secretion [GO:0014046]; establishment of protein localization to mitochondrion [GO:0072655]; hemopoiesis [GO:0030097]; intracellular signal transduction [GO:0035556]; maintenance of protein location in mitochondrion [GO:0072656]; mitochondrion organization [GO:0007005]; mitochondrion to lysosome transport [GO:0099074]; mitophagy [GO:0000423]; negative regulation of autophagosome assembly [GO:1902902]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide [GO:1903751]; negative regulation of JNK cascade [GO:0046329]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mitochondrial fission [GO:0090258]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-serine autophosphorylation [GO:0036289]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of cristae formation [GO:1903852]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine secretion [GO:0033603]; positive regulation of free ubiquitin chain polymerization [GO:1904544]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of peptidase activity [GO:0010952]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of synaptic transmission, dopaminergic [GO:0032226]; positive regulation of translation [GO:0045727]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mitochondrion organization [GO:0010821]; regulation of oxidative phosphorylation [GO:0002082]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of protein targeting to mitochondrion [GO:1903214]; regulation of protein ubiquitination [GO:0031396]; regulation of protein-containing complex assembly [GO:0043254]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of synaptic vesicle transport [GO:1902803]; respiratory electron transport chain [GO:0022904]; response to ischemia [GO:0002931]; response to oxidative stress [GO:0006979]; TORC2 signaling [GO:0038203]; ubiquitin-dependent protein catabolic process [GO:0006511]" astrocyte projection [GO:0097449]; axon [GO:0030424]; cell body [GO:0044297]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; growth cone [GO:0030426]; Lewy body [GO:0097413]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; calcium-dependent protein kinase activity [GO:0010857]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein kinase activity [GO:0004672]; protein kinase B binding [GO:0043422]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein-containing complex binding [GO:0044877]; TORC2 complex binding [GO:1904841]; ubiquitin protein ligase binding [GO:0031625] 0.60526 0.43844 AYGLGRPGPAAGCVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2863 0 0 0 0 0 0 0 0 0 0 Q9BXM9 FSD1L_HUMAN FSD1-like protein (Coiled-coil domain-containing protein 10) (FSD1 N-terminal-like protein) FSD1L CCDC10 CSDUFD1 FSD1CL FSD1NL Homo sapiens (Human) 0.83575 0.19254 ESMINCIKQEQAR 0 0 9.83875 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BXN1 ASPN_HUMAN Asporin (Periodontal ligament-associated protein 1) (PLAP-1) ASPN PLAP1 SLRR1C UNQ215/PRO241 Homo sapiens (Human) bone mineralization [GO:0030282]; negative regulation of tooth mineralization [GO:0070171]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; response to fluoride [GO:1902617] cell projection [GO:0042995]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615] calcium ion binding [GO:0005509] 0.92019 -0.92947 ISTVELEDFK 11.2532 0 0 8.99223 8.90427 9.08058 0 0 0 10.8981 0 0 9.11437 0 11.6908 10.5258 11.3245 0 0 0 0 0 0 0 0 0 0 Q9BXP2 S12A9_HUMAN Solute carrier family 12 member 9 (Cation-chloride cotransporter 6) (hCCC6) (Cation-chloride cotransporter-interacting protein 1) (CCC-interacting protein 1) (hCIP1) (Potassium-chloride transporter 9) (WO3.3) SLC12A9 CCC6 CIP1 Homo sapiens (Human) cell volume homeostasis [GO:0006884]; chloride ion homeostasis [GO:0055064]; chloride transmembrane transport [GO:1902476]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573] extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886] chloride:monoatomic cation symporter activity [GO:0015377]; potassium:chloride symporter activity [GO:0015379] 0.9463 -1.3499 NVVLARASGALPPERLSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.2961 0 0 0 0 0 0 0 0 0 0 0 0 Q9BXP5 SRRT_HUMAN Serrate RNA effector molecule homolog (Arsenite-resistance protein 2) SRRT ARS2 ASR2 Homo sapiens (Human) mRNA processing [GO:0006397]; neuronal stem cell population maintenance [GO:0097150]; positive regulation of neurogenesis [GO:0050769]; primary miRNA processing [GO:0031053]; regulation of DNA-templated transcription [GO:0006355]; response to arsenic-containing substance [GO:0046685] cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904] DNA binding [GO:0003677]; mRNA cap binding complex binding [GO:0140262]; protein-macromolecule adaptor activity [GO:0030674]; RNA binding [GO:0003723] 0.97024 -3.2535 AEIISLCK 0 10.3243 11.9462 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BXQ6 T121B_HUMAN Transmembrane protein 121B (Cat eye syndrome critical region protein 6) TMEM121B CECR6 Homo sapiens (Human) 0.94786 -1.3661 LQPLFLRGGSFRGR 0 0 0 8.8334 0 0 0 0 0 0 0 0 0 0 0 0 10.4239 0 0 0 0 0 0 0 0 0 0 Q9BXR0 TGT_HUMAN Queuine tRNA-ribosyltransferase catalytic subunit 1 (EC 2.4.2.64) (Guanine insertion enzyme) (tRNA-guanine transglycosylase) QTRT1 TGT TGUT Homo sapiens (Human) tRNA modification [GO:0006400]; tRNA-guanine transglycosylation [GO:0101030] mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transferase complex [GO:1990234] metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; queuine tRNA-ribosyltransferase activity [GO:0008479] 0.83266 0.20138 GITTEQLDALGCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.88379 0 0 0 Q9BXR5 TLR10_HUMAN Toll-like receptor 10 (CD antigen CD290) TLR10 UNQ315/PRO358 Homo sapiens (Human) cellular response to bacterial lipopeptide [GO:0071221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; toll-like receptor signaling pathway [GO:0002224] membrane [GO:0016020]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] "identical protein binding [GO:0042802]; lipopeptide binding [GO:0071723]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; signaling receptor activity [GO:0038023]; Toll-like receptor 2 binding [GO:0035663]; transmembrane signaling receptor activity [GO:0004888]" 0.60496 0.43761 ETIHLMALR 8.6218 0 8.27826 0 12.7673 11.7694 14.467 0 8.18676 0 14.659 14.5881 12.0751 12.2659 12.3802 13.0233 12.7341 12.4226 0 0 9.20901 0 0 0 0 0 0 Q9BXR6 FHR5_HUMAN Complement factor H-related protein 5 (FHR-5) CFHR5 CFHL5 FHR5 Homo sapiens (Human) "complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; cytolysis by host of symbiont cells [GO:0051838]; negative regulation of protein binding [GO:0032091]" extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991] complement component C3b binding [GO:0001851]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982] 0.96335 -2.2406 GECHVPILEANVDAQPK 0 10.7571 0 0 0 0 10.6696 0 10.8764 0 0 0 0 0 0 0 0 0 0 0 0 0 9.6331 0 0 0 0 Q9BXS0 COPA1_HUMAN Collagen alpha-1(XXV) chain (Alzheimer disease amyloid-associated protein) (AMY) (CLAC-P) [Cleaved into: Collagen-like Alzheimer amyloid plaque component (CLAC)] COL25A1 Homo sapiens (Human) collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886] amyloid-beta binding [GO:0001540]; heparin binding [GO:0008201]; identical protein binding [GO:0042802] 0.31062 0.79399 GEPGLPGAVGQNGIPGPKGEPGEQGEK 0 0 0 0 0 10.9299 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BXS6 NUSAP_HUMAN Nucleolar and spindle-associated protein 1 (NuSAP) NUSAP1 ANKT BM-037 PRO0310 Homo sapiens (Human) establishment of mitotic spindle localization [GO:0040001]; mitotic chromosome condensation [GO:0007076]; mitotic cytokinesis [GO:0000281]; mitotic sister chromatid segregation [GO:0000070]; positive regulation of mitotic nuclear division [GO:0045840] chromosome [GO:0005694]; cytoplasm [GO:0005737]; microtubule [GO:0005874]; mitotic spindle [GO:0072686]; nucleolus [GO:0005730] DNA binding [GO:0003677]; microtubule binding [GO:0008017]; RNA binding [GO:0003723] 0.78495 0.25586 TAITTPNFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.26725 0 0 0 0 0 0 0 0 Q9BXT2 CCG6_HUMAN Voltage-dependent calcium channel gamma-6 subunit (Neuronal voltage-gated calcium channel gamma-6 subunit) CACNG6 Homo sapiens (Human) calcium ion transport [GO:0006816]; regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1902514] L-type voltage-gated calcium channel complex [GO:1990454]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891] calcium channel regulator activity [GO:0005246]; voltage-gated calcium channel activity [GO:0005245] 0.2961 0.81605 GAEFLLR 0 0 0 0 9.42545 0 0 0 0 0 0 0 0 0 0 10.7985 0 10.9986 0 0 0 0 0 0 0 0 0 Q9BXT4 TDRD1_HUMAN Tudor domain-containing protein 1 (Cancer/testis antigen 41.1) (CT41.1) TDRD1 Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; P granule [GO:0043186]; pi-body [GO:0071546] metal ion binding [GO:0046872] 0.8982 -0.55855 IMFSDLRSLQLK 0 10.9767 10.5303 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BXT5 TEX15_HUMAN Testis-expressed protein 15 (Cancer/testis antigen 42) (CT42) TEX15 Homo sapiens (Human) cell differentiation [GO:0030154]; DNA methylation-dependent heterochromatin formation [GO:0006346]; DNA repair [GO:0006281]; male meiotic nuclear division [GO:0007140]; regulation of double-strand break repair via homologous recombination [GO:0010569]; retrotransposon silencing [GO:0010526]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130] cytoplasm [GO:0005737]; nucleus [GO:0005634] 0.96932 -5.6382 FLKNSPDPTQK 0 0 0 0 0 0 0 0 0 0 0 10.0739 0 0 0 0 0 0 0 0 0 0 0 9.41075 10.6295 0 0 Q9BXT6 M10L1_HUMAN RNA helicase Mov10l1 (EC 3.6.4.13) (Moloney leukemia virus 10-like protein 1) (MOV10-like protein 1) MOV10L1 Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; male meiosis I [GO:0007141]; ncRNA-mediated post-transcriptional gene silencing [GO:0035194]; piRNA processing [GO:0034587]; spermatogenesis [GO:0007283] cytosol [GO:0005829]; P granule [GO:0043186]; pi-body [GO:0071546] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.95492 -1.6049 EPFSWKK 0 10.1491 0 0 0 10.9576 0 8.90881 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BXT8 RNF17_HUMAN RING finger protein 17 (Tudor domain-containing protein 4) RNF17 TDRD4 Homo sapiens (Human) spermatid development [GO:0007286] cytoplasm [GO:0005737]; nucleus [GO:0005634] identical protein binding [GO:0042802]; metal ion binding [GO:0046872] 0.96894 -7.0535 ALQLSPSLR 0 0 9.5224 0 9.51515 11.798 0 0 0 0 0 0 0 0 0 0 9.42044 10.3829 0 9.18274 0 0 0 0 0 0 12.3351 Q9BXU1 STK31_HUMAN Serine/threonine-protein kinase 31 (EC 2.7.11.1) (Serine/threonine-protein kinase NYD-SPK) (Sugen kinase 396) (SgK396) STK31 SGK396 Homo sapiens (Human) protein phosphorylation [GO:0006468] acrosomal vesicle [GO:0001669] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96762 -3.7482 KQLIEYLNKSPSVDHLLSIK 0 0 8.34674 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BXU2 TX13B_HUMAN Testis-expressed protein 13B TEX13B Homo sapiens (Human) mRNA binding [GO:0003729] 0.90838 -0.74269 RVQWLQGFAK 0 0 0 0 0 0 0 0 0 10.2722 0 9.57061 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BXU3 TX13A_HUMAN Testis-expressed protein 13A TEX13A Homo sapiens (Human) metal ion binding [GO:0046872]; mRNA binding [GO:0003729] 0.95043 -1.4073 IDHQEHPRDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.911 0 0 0 0 0 0 0 0 Q9BXU7 UBP26_HUMAN Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.4.19.12) (Deubiquitinating enzyme 26) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) USP26 Homo sapiens (Human) G1/S transition of mitotic cell cycle [GO:0000082]; protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] cysteine-type deubiquitinase activity [GO:0004843]; cysteine-type endopeptidase activity [GO:0004197] 0.924 -1.1723 DLYEDKNIR 0 0 0 0 0 0 0 0 0 0 0 10.4389 0 0 0 0 0 0 0 0 0 0 9.66123 0 0 0 0 Q9BXU8 FHL17_HUMAN Ferritin heavy polypeptide-like 17 (Cancer/testis antigen 38) (CT38) FTHL17 Homo sapiens (Human) intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826] cytoplasm [GO:0005737] ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198] 0.90584 -0.72795 LSDDKMEHAQK 0 0 0 0 0 0 0 0 0 9.93409 0 0 0 0 0 0 0 8.73545 0 0 0 0 0 0 0 0 0 Q9BXW4 MLP3C_HUMAN Microtubule-associated proteins 1A/1B light chain 3C (Autophagy-related protein LC3 C) (Autophagy-related ubiquitin-like modifier LC3 C) (MAP1 light chain 3-like protein 3) (MAP1A/MAP1B light chain 3 C) (MAP1A/MAP1B LC3 C) (Microtubule-associated protein 1 light chain 3 gamma) MAP1LC3C Homo sapiens (Human) aggrephagy [GO:0035973]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]; protein exit from endoplasmic reticulum [GO:0032527] autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; microtubule [GO:0005874]; organelle membrane [GO:0031090] ubiquitin protein ligase binding [GO:0031625] 0.83655 0.19447 IPSVRPFK 11.7936 0 11.7826 0 0 11.8131 12.012 11.8912 11.8267 12.2498 12.2931 12.3894 0 0 0 0 12.1583 0 0 11.756 0 11.5683 11.5469 11.6644 0 0 0 Q9BXW6 OSBL1_HUMAN Oxysterol-binding protein-related protein 1 (ORP-1) (OSBP-related protein 1) OSBPL1A ORP1 OSBP8 OSBPL1 OSBPL1B Homo sapiens (Human) bile acid biosynthetic process [GO:0006699]; cholesterol metabolic process [GO:0008203]; vesicle-mediated transport [GO:0016192] cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; membrane [GO:0016020]; organelle membrane contact site [GO:0044232] cholesterol binding [GO:0015485]; phospholipid binding [GO:0005543]; sterol transporter activity [GO:0015248] 0.96902 -4.0007 LEELLLAAAREGK 0 0 0 0 0 0 0 0 0 0 8.96541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BXW9 FACD2_HUMAN Fanconi anemia group D2 protein (Protein FACD2) FANCD2 FACD Homo sapiens (Human) brain morphogenesis [GO:0048854]; cellular response to oxidative stress [GO:0034599]; double-strand break repair involved in meiotic recombination [GO:1990918]; gamete generation [GO:0007276]; homologous chromosome pairing at meiosis [GO:0007129]; interstrand cross-link repair [GO:0036297]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; neuronal stem cell population maintenance [GO:0097150]; regulation of CD40 signaling pathway [GO:2000348]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of inflammatory response [GO:0050727]; regulation of regulatory T cell differentiation [GO:0045589]; response to gamma radiation [GO:0010332] chromatin [GO:0000785]; condensed chromosome [GO:0000793]; cytosol [GO:0005829]; DNA repair complex [GO:1990391]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA polymerase binding [GO:0070182] 0.95947 -1.9203 DLQGEEIK 0 8.77995 10.4195 0 0 0 8.75986 0 0 0 0 10.1744 8.38681 0 0 0 0 0 0 10.0849 0 0 0 0 0 0 0 Q9BXX0 EMIL2_HUMAN EMILIN-2 (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10) EMILIN2 Homo sapiens (Human) cell adhesion mediated by integrin [GO:0033627]; negative regulation of cell migration [GO:0030336]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood coagulation [GO:0030194]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of platelet aggregation [GO:1901731]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127] collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; EMILIN complex [GO:1990971]; extracellular region [GO:0005576] extracellular matrix constituent conferring elasticity [GO:0030023] 0.9697 -3.1709 GAINGEVGDLK 0 9.23424 0 0 0 0 0 0 0 10.5377 0 0 0 0 0 0 0 0 0 0 0 0 0 8.43987 10.4871 0 0 Q9BXX2 AN30B_HUMAN Ankyrin repeat domain-containing protein 30B (Serologically defined breast cancer antigen NY-BR-1.1) ANKRD30B Homo sapiens (Human) 0.96713 -2.8623 DIKTINHK 9.92932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.399 0 0 0 0 0 0 9.92355 0 0 0 Q9BXX3 AN30A_HUMAN Ankyrin repeat domain-containing protein 30A (Serologically defined breast cancer antigen NY-BR-1) ANKRD30A Homo sapiens (Human) 0.96934 -5.6829 EIMSPAKETSEK 0 0 0 0 0 0 8.66697 0 0 10.6444 0 0 0 9.99067 9.50819 10.9814 10.4887 8.45282 10.1262 0 9.1724 10.3551 9.13843 10.3348 10.6486 11.8204 12.918 Q9BXY0 MAK16_HUMAN Protein MAK16 homolog (NNP78) (Protein RBM13) MAK16 RBM13 Homo sapiens (Human) maturation of 5.8S rRNA [GO:0000460]; maturation of LSU-rRNA [GO:0000470] "intracellular membrane-bounded organelle [GO:0043231]; nucleolus [GO:0005730]; preribosome, large subunit precursor [GO:0030687]" RNA binding [GO:0003723] 0.82973 0.20722 LDASSDEDQDGKSSSEEEEEK 0 0 0 0 0 0 0 0 8.72417 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BXY4 RSPO3_HUMAN R-spondin-3 (Protein with TSP type-1 repeat) (hPWTSR) (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) RSPO3 PWTSR THSD2 Homo sapiens (Human) "blood vessel remodeling [GO:0001974]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; canonical Wnt signaling pathway [GO:0060070]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of non-canonical Wnt signaling pathway [GO:2000052]; positive regulation of Wnt signaling pathway [GO:0030177]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; sprouting angiogenesis [GO:0002040]" extracellular region [GO:0005576] frizzled binding [GO:0005109]; heparin binding [GO:0008201]; signaling receptor binding [GO:0005102] 0.4796 0.62505 GTETRVREIIQHPSAK 0 0 0 0 0 0 0 0 11.4312 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BXY5 CAYP2_HUMAN Calcyphosin-2 (Calcyphosine-2) CAPS2 UG0636c06 Homo sapiens (Human) calcium ion binding [GO:0005509] 0.96956 -3.3069 GVAATSR 9.6556 9.53126 9.52503 0 0 0 9.99506 9.93627 9.89218 11.2809 10.0649 0 0 0 0 0 0 0 0 0 0 10.0369 0 0 0 0 0 Q9BY07 S4A5_HUMAN Electrogenic sodium bicarbonate cotransporter 4 (NBCe2) (Solute carrier family 4 member 5) SLC4A5 NBC4 Homo sapiens (Human) bicarbonate transport [GO:0015701]; cerebrospinal fluid secretion [GO:0033326]; epithelial cell development [GO:0002064]; mitochondrion distribution [GO:0048311]; regulation of gene expression [GO:0010468]; regulation of intracellular pH [GO:0051453]; regulation of systemic arterial blood pressure [GO:0003073]; renal system process [GO:0003014]; retina development in camera-type eye [GO:0060041]; transmembrane transport [GO:0055085] apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; membrane [GO:0016020]; plasma membrane [GO:0005886] monoatomic anion transmembrane transporter activity [GO:0008509]; sodium:bicarbonate symporter activity [GO:0008510]; solute:inorganic anion antiporter activity [GO:0005452] 0.96934 -6.1949 FFGGLCLDIK 0 0 0 0 0 0 0 0 0 0 0 0 0 8.80265 0 0 9.29804 0 0 0 10.078 0 9.93908 0 0 0 0 Q9BY11 PACN1_HUMAN Protein kinase C and casein kinase substrate in neurons protein 1 (Syndapin-1) PACSIN1 KIAA1379 Homo sapiens (Human) actin filament organization [GO:0007015]; cytoskeleton organization [GO:0007010]; negative regulation of endocytosis [GO:0045806]; neuron projection morphogenesis [GO:0048812]; plasma membrane tubulation [GO:0097320]; positive regulation of dendrite development [GO:1900006]; protein localization to membrane [GO:0072657]; protein localization to plasma membrane [GO:0072659]; regulation of endocytosis [GO:0030100]; synaptic vesicle endocytosis [GO:0048488] axon terminus [GO:0043679]; COPI-coated vesicle [GO:0030137]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; endosome [GO:0005768]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor ribbon synapse [GO:0098684]; plasma membrane [GO:0005886]; presynaptic endocytic zone [GO:0098833]; ruffle membrane [GO:0032587]; synapse [GO:0045202] cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; phospholipid binding [GO:0005543] 0.96955 -4.1696 AGDELTK 13.242 0 0 0 0 0 0 0 0 9.53594 0 0 0 0 0 0 0 0 0 0 0 9.51235 9.2754 0 0 0 0 Q9BY12 SCAPE_HUMAN S phase cyclin A-associated protein in the endoplasmic reticulum (S phase cyclin A-associated protein in the ER) (Zinc finger protein 291) SCAPER KIAA1454 ZNF291 MSTP063 Homo sapiens (Human) antral ovarian follicle growth [GO:0001547]; retina development in camera-type eye [GO:0060041]; seminiferous tubule development [GO:0072520]; spermatogenesis [GO:0007283] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; ooplasm [GO:1990917]; sperm head [GO:0061827] nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270] 0.96912 -5.7408 ALEAERQAR 9.00144 9.01176 0 0 0 0 9.58982 0 10.0807 0 0 8.27603 9.29506 0 9.69364 0 0 0 0 8.97937 0 0 0 0 0 10.0857 0 Q9BY21 GPR87_HUMAN G-protein coupled receptor 87 (G-protein coupled receptor 95) GPR87 GPR95 FKSG78 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of adenylate cyclase activity [GO:0007194] plasma membrane [GO:0005886] G protein-coupled purinergic nucleotide receptor activity [GO:0045028] 0.95997 -1.9369 GFNLTLAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.16621 10.2836 0 10.1558 0 10.2641 0 Q9BY31 ZN717_HUMAN Zinc finger protein 717 (Krueppel-like factor X17) ZNF717 Homo sapiens (Human) nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96408 -2.2586 CNECRKTFSQK 0 0 9.15494 0 0 0 0 0 14.9437 0 14.8811 0 9.36448 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BY41 HDAC8_HUMAN Histone deacetylase 8 (HD8) (EC 3.5.1.98) (Protein deacetylase HDAC8) (EC 3.5.1.-) (Protein decrotonylase HDAC8) (EC 3.5.1.-) HDAC8 HDACL1 CDA07 Homo sapiens (Human) chromatin organization [GO:0006325]; histone deacetylation [GO:0016575]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204] cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA-binding transcription factor binding [GO:0140297]; histone deacetylase activity [GO:0004407]; histone decrotonylase activity [GO:0160009]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; protein lysine deacetylase activity [GO:0033558] 0.86967 0.045823 EVYQAFNPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.32802 0 0 0 0 0 0 0 0 0 0 0 0 Q9BY42 RTF2_HUMAN Replication termination factor 2 (RTF2) (Replication termination factor 2 domain-containing protein 1) RTF2 C20orf43 RTFDC1 AD-007 CDA05 HSPC164 HSPC169 Homo sapiens (Human) cellular response to hydroxyurea [GO:0072711]; mitotic DNA replication termination [GO:1902979]; regulation of DNA stability [GO:0097752] nucleus [GO:0005634]; replication fork [GO:0005657] DNA binding [GO:0003677] 0.92442 -1.0663 SIKNVTELK 0 0 0 0 0 0 0 0 0 9.87304 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BY43 CHM4A_HUMAN Charged multivesicular body protein 4a (Chromatin-modifying protein 4a) (CHMP4a) (SNF7 homolog associated with Alix-2) (SNF7-1) (hSnf-1) (Vacuolar protein sorting-associated protein 32-1) (Vps32-1) (hVps32-1) CHMP4A C14orf123 SHAX2 CDA04 HSPC134 Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; late endosome to lysosome transport [GO:1902774]; late endosome to vacuole transport via multivesicular body sorting pathway [GO:0032511]; macroautophagy [GO:0016236]; membrane fission [GO:0090148]; membrane invagination [GO:0010324]; midbody abscission [GO:0061952]; mitotic metaphase plate congression [GO:0007080]; multivesicular body assembly [GO:0036258]; multivesicular body sorting pathway [GO:0071985]; multivesicular body-lysosome fusion [GO:0061763]; negative regulation of cell death [GO:0060548]; nervous system process [GO:0050877]; nuclear membrane reassembly [GO:0031468]; nucleus organization [GO:0006997]; plasma membrane repair [GO:0001778]; plasma membrane tubulation [GO:0097320]; post-translational protein targeting to endoplasmic reticulum membrane [GO:0006620]; protein polymerization [GO:0051258]; regulation of mitotic spindle assembly [GO:1901673]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; vesicle budding from membrane [GO:0006900]; vesicle fusion with vacuole [GO:0051469]; viral budding from plasma membrane [GO:0046761]; viral budding via host ESCRT complex [GO:0039702] amphisome membrane [GO:1904930]; autophagosome membrane [GO:0000421]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; ESCRT III complex [GO:0000815]; kinetochore [GO:0000776]; kinetochore microtubule [GO:0005828]; lysosomal membrane [GO:0005765]; membrane coat [GO:0030117]; midbody [GO:0030496]; multivesicular body [GO:0005771]; multivesicular body membrane [GO:0032585]; nuclear pore [GO:0005643]; nucleus [GO:0005634]; plasma membrane [GO:0005886] ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803] 0.88402 -0.2981 EKGPTPEEAIQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.77037 0 0 0 0 0 0 0 0 Q9BY66 KDM5D_HUMAN Lysine-specific demethylase 5D (EC 1.14.11.67) (Histocompatibility Y antigen) (H-Y) (Histone demethylase JARID1D) (Jumonji/ARID domain-containing protein 1D) (Protein SmcY) ([histone H3]-trimethyl-L-lysine(4) demethylase 5D) KDM5D HY HYA JARID1D KIAA0234 SMCY Homo sapiens (Human) chromatin remodeling [GO:0006338]; regulation of androgen receptor signaling pathway [GO:0060765]; T cell antigen processing and presentation [GO:0002457] fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; histone demethylase activity [GO:0032452]; histone H3K4 demethylase activity [GO:0032453]; histone H3K4me/H3K4me2/H3K4me3 demethylase activity [GO:0034647]; metal ion binding [GO:0046872]; nuclear androgen receptor binding [GO:0050681] 0.96259 -2.5032 FEHQGSRTR 0 0 0 9.60378 0 0 0 0 0 0 0 0 0 8.63008 0 0 0 9.85611 0 0 9.9257 0 0 9.15831 0 9.83567 8.3847 Q9BY71 LRRC3_HUMAN Leucine-rich repeat-containing protein 3 LRRC3 C21orf102 LRRC3A UNQ9233/PRO31982 Homo sapiens (Human) plasma membrane [GO:0005886] 0.67378 0.39371 DPIGPGP 0 0 0 0 0 0 0 0 0 0 0 0 9.32805 0 9.41424 8.91522 0 0 0 8.45348 8.55182 9.25257 0 0 0 8.93858 10.45 Q9BY76 ANGL4_HUMAN Angiopoietin-related protein 4 (Angiopoietin-like protein 4) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP) [Cleaved into: ANGPTL4 N-terminal chain; ANGPTL4 C-terminal chain] ANGPTL4 ARP4 HFARP PGAR PP1158 PSEC0166 UNQ171/PRO197 Homo sapiens (Human) angiogenesis [GO:0001525]; endothelial cell apoptotic process [GO:0072577]; lipid metabolic process [GO:0006629]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lipoprotein lipase activity [GO:0051005]; positive regulation of angiogenesis [GO:0045766]; protein unfolding [GO:0043335]; response to hypoxia [GO:0001666]; triglyceride homeostasis [GO:0070328] blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615] enzyme inhibitor activity [GO:0004857]; identical protein binding [GO:0042802] 0.84302 0.15073 IQHLQSQFGLLDHK 0 0 0 0 0 0 0 0 0 0 0 0 11.55 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BY77 PDIP3_HUMAN Polymerase delta-interacting protein 3 (46 kDa DNA polymerase delta interaction protein) (p46) (S6K1 Aly/REF-like target) (SKAR) POLDIP3 KIAA1649 PDIP46 Homo sapiens (Human) poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of translation [GO:0045727] cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] mRNA binding [GO:0003729]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723] 0.88363 -0.1815 ALTNMSRTLVNK 0 0 0 0 9.81436 9.77091 0 0 9.04759 0 0 9.15264 0 0 10.5252 0 0 0 0 0 0 0 0 0 0 0 0 Q9BY78 RNF26_HUMAN E3 ubiquitin-protein ligase RNF26 (EC 2.3.2.27) (RING finger protein 26) RNF26 Homo sapiens (Human) endosome organization [GO:0007032]; negative regulation of defense response to virus [GO:0050687]; protein K11-linked ubiquitination [GO:0070979]; protein localization to perinuclear region of cytoplasm [GO:1905719]; protein ubiquitination [GO:0016567]; regulation of type I interferon production [GO:0032479]; ubiquitin-dependent protein catabolic process [GO:0006511] endoplasmic reticulum membrane [GO:0005789] molecular function activator activity [GO:0140677]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.84732 0.1676 TVLLLPCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1472 0 0 0 0 0 0 0 0 0 Q9BY89 K1671_HUMAN Uncharacterized protein KIAA1671 KIAA1671 Homo sapiens (Human) 0.95993 -1.8572 DCGRVPLDIK 0 10.1829 10.6842 0 0 0 10.7428 0 10.4328 10.4651 12.096 10.3201 11.8565 0 10.9791 0 0 10.192 9.31981 0 0 0 0 0 0 0 0 Q9BYB0 SHAN3_HUMAN SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) SHANK3 KIAA1650 PROSAP2 PSAP2 Homo sapiens (Human) "adult behavior [GO:0030534]; AMPA glutamate receptor clustering [GO:0097113]; brain morphogenesis [GO:0048854]; dendritic spine morphogenesis [GO:0060997]; guanylate kinase-associated protein clustering [GO:0097117]; learning [GO:0007612]; MAPK cascade [GO:0000165]; memory [GO:0007613]; negative regulation of actin filament bundle assembly [GO:0032232]; negative regulation of cell volume [GO:0045794]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of AMPA receptor activity [GO:2000969]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of glutamate receptor signaling pathway [GO:1900451]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of synapse structural plasticity [GO:0051835]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density assembly [GO:0097107]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of long-term synaptic depression [GO:1900452]; regulation of long-term synaptic potentiation [GO:1900271]; social behavior [GO:0035176]; striatal medium spiny neuron differentiation [GO:0021773]; synapse assembly [GO:0007416]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625]" ciliary membrane [GO:0060170]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; neuron projection [GO:0043005]; neuron spine [GO:0044309]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] actin binding [GO:0003779]; ionotropic glutamate receptor binding [GO:0035255]; protein self-association [GO:0043621]; scaffold protein binding [GO:0097110]; SH3 domain binding [GO:0017124]; synaptic receptor adaptor activity [GO:0030160]; zinc ion binding [GO:0008270] 0.97002 -4.1466 ITPAEISSLFER 0 0 0 0 0 10.2456 0 0 0 8.41967 0 0 10.3856 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BYB4 GNB1L_HUMAN Guanine nucleotide-binding protein subunit beta-like protein 1 (G protein subunit beta-like protein 1) (DGCRK3) (WD repeat-containing protein 14) (WD40 repeat-containing protein deleted in VCFS) (WDVCF) GNB1L GY2 KIAA1645 WDR14 FKSG1 Homo sapiens (Human) 0.96497 -2.2819 DLKLCLWDLAEGR 0 0 0 0 0 9.5542 0 10.5277 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BYC2 SCOT2_HUMAN "Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial (EC 2.8.3.5) (3-oxoacid CoA-transferase 2A) (Testis-specific succinyl-CoA:3-oxoacid CoA-transferase) (SCOT-t)" OXCT2 FKSG25 Homo sapiens (Human) cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; motile cilium [GO:0031514] succinyl-CoA:3-oxo-acid CoA-transferase activity [GO:0008260] 0.82023 0.21884 VVVTMQHCTK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.51227 0 0 0 0 0 0 9.90394 0 0 0 0 0 0 Q9BYD2 RM09_HUMAN "Large ribosomal subunit protein bL9m (39S ribosomal protein L9, mitochondrial) (L9mt) (MRP-L9)" MRPL9 Homo sapiens (Human) mitochondrial translation [GO:0032543]; translation [GO:0006412] mitochondrial inner membrane [GO:0005743]; mitochondrial large ribosomal subunit [GO:0005762]; mitochondrial ribosome [GO:0005761]; mitochondrion [GO:0005739] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.96869 -3.0203 LEVGMKNNVK 0 0 0 0 0 0 0 0 9.15975 0 0 0 10.7021 0 0 0 9.64151 0 0 0 0 0 0 0 0 0 0 Q9BYD9 ACTT3_HUMAN Actin-related protein T3 (ARP-T3) (Actin-related protein M1) ACTRT3 ARPM1 Homo sapiens (Human) cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; male germ cell nucleus [GO:0001673] 0.91398 -0.80046 KPDCLEKVYQLPDGK 0 0 0 0 10.1719 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BYE2 TMPSD_HUMAN Transmembrane protease serine 13 (EC 3.4.21.-) (Membrane-type mosaic serine protease) (Mosaic serine protease) TMPRSS13 MSP TMPRSS11 Homo sapiens (Human) proteolysis [GO:0006508] blood microparticle [GO:0072562]; membrane [GO:0016020] scavenger receptor activity [GO:0005044]; serine-type endopeptidase activity [GO:0004252] 0.9323 -1.2662 MMCAGDLRGGR 0 0 0 9.258 9.03546 9.28091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BYE7 PCGF6_HUMAN Polycomb group RING finger protein 6 (Mel18 and Bmi1-like RING finger) (RING finger protein 134) PCGF6 MBLR RNF134 Homo sapiens (Human) chromatin remodeling [GO:0006338]; histone H2A-K119 monoubiquitination [GO:0036353]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PcG protein complex [GO:0031519]; PRC1 complex [GO:0035102] metal ion binding [GO:0046872] 0.93886 -1.3186 SCIVRHFYYSNRCPK 0 0 0 9.6343 9.45539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BYG3 MK67I_HUMAN MKI67 FHA domain-interacting nucleolar phosphoprotein (Nucleolar phosphoprotein Nopp34) (Nucleolar protein interacting with the FHA domain of pKI-67) (hNIFK) NIFK MKI67IP NOPP34 Homo sapiens (Human) "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; protein-containing complex assembly [GO:0065003]; rRNA metabolic process [GO:0016072]; rRNA transcription [GO:0009303]" chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] RNA binding [GO:0003723] 0.93244 -1.2858 TNRQTSTKGQVLR 0 0 0 0 0 0 0 0 0 9.58305 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BYG4 PAR6G_HUMAN Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D) PARD6G PAR6G Homo sapiens (Human) cell division [GO:0051301]; centrosome cycle [GO:0007098]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; regulation of cellular localization [GO:0060341] apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell cortex [GO:0005938]; cytosol [GO:0005829]; nucleus [GO:0005634]; PAR polarity complex [GO:0120157]; plasma membrane [GO:0005886]; tight junction [GO:0070160] 0.88479 -0.29616 LLSSLRADPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.32384 0 Q9BYG7 MSTRO_HUMAN Protein maestro (Male-specific transcription in the developing reproductive organs) (Protein B29) MRO B29 C18orf3 Homo sapiens (Human) nucleolus [GO:0005730] 0.69536 0.37677 EEYSFQSEEDQR 12.2212 11.6713 11.739 8.9125 0 0 9.84837 11.6801 11.7771 0 11.6515 11.6902 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BYG8 GSDMC_HUMAN "Gasdermin-C (Melanoma-derived leucine zipper-containing extranuclear factor) [Cleaved into: Gasdermin-C, N-terminal (GSDMC-NT); Gasdermin-C, C-terminal (GSDMC-CT)]" GSDMC MLZE Homo sapiens (Human) defense response to bacterium [GO:0042742]; pyroptosis [GO:0070269] cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886] "phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylserine binding [GO:0001786]" 0.9555 -1.5515 NLVKEIGSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2189 0 0 0 0 0 0 0 0 0 Q9BYH1 SE6L1_HUMAN Seizure 6-like protein SEZ6L KIAA0927 UNQ2542/PRO6094 Homo sapiens (Human) regulation of protein kinase C signaling [GO:0090036]; synapse maturation [GO:0060074] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuronal cell body [GO:0043025] 0.846 0.15391 IHVGEEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0893 0 0 0 0 0 0 0 0 0 Q9BYH8 IKBZ_HUMAN NF-kappa-B inhibitor zeta (I-kappa-B-zeta) (IkB-zeta) (IkappaBzeta) (IL-1 inducible nuclear ankyrin-repeat protein) (INAP) (Molecule possessing ankyrin repeats induced by lipopolysaccharide) (MAIL) NFKBIZ IKBZ INAP MAIL Homo sapiens (Human) B cell proliferation [GO:0042100]; B cell receptor apoptotic signaling pathway [GO:1990117]; cellular response to interleukin-17 [GO:0097398]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; chromatin remodeling [GO:0006338]; chronic inflammatory response [GO:0002544]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; epithelial cell apoptotic process [GO:1904019]; establishment of skin barrier [GO:0061436]; execution phase of apoptosis [GO:0097194]; homeostasis of number of cells within a tissue [GO:0048873]; inflammatory response to wounding [GO:0090594]; isotype switching [GO:0045190]; keratinocyte activation [GO:0032980]; keratinocyte differentiation [GO:0030216]; keratinocyte proliferation [GO:0043616]; mRNA transcription by RNA polymerase II [GO:0042789]; plasma cell differentiation [GO:0002317]; positive regulation of inflammatory response [GO:0050729]; positive regulation of T-helper 17 cell differentiation [GO:2000321]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; response to cisplatin [GO:0072718]; response to folic acid [GO:0051593]; response to Gram-positive bacterium [GO:0140459]; response to xenobiotic stimulus [GO:0009410]; spleen development [GO:0048536]; T cell mediated immunity [GO:0002456]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 cell differentiation [GO:0045063]; T-helper 17 cell differentiation [GO:0072539]; toll-like receptor signaling pathway [GO:0002224]; transcription preinitiation complex assembly [GO:0070897] cytoplasmic ribonucleoprotein granule [GO:0036464]; nuclear speck [GO:0016607]; nucleus [GO:0005634] RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; transcription coregulator activity [GO:0003712] 0.96226 -2.5392 ELLLHIRSHKQK 0 0 0 0 0 9.87386 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BYI3 HYCCI_HUMAN Hyccin (Down-regulated by CTNNB1 protein A) HYCC1 DRCTNNB1A FAM126A Homo sapiens (Human) myelination [GO:0042552]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; protein localization to plasma membrane [GO:0072659] cytosol [GO:0005829]; neuron projection [GO:0043005]; plasma membrane [GO:0005886] 0.73507 0.32853 ASLPHGPMK 0 0 0 0 0 0 0 0 0 9.44211 0 0 0 0 0 0 0 0 0 0 0 9.84604 9.54127 9.7212 0 0 0 Q9BYJ1 LOXE3_HUMAN Hydroperoxide isomerase ALOXE3 (Epidermis-type lipoxygenase 3) (Epidermal LOX-3) (e-LOX-3) (eLOX-3) (Hydroperoxy dehydratase ALOXE3) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152) (Hydroperoxy icosatetraenoate isomerase) (EC 5.4.4.7) ALOXE3 Homo sapiens (Human) arachidonic acid metabolic process [GO:0019369]; ceramide biosynthetic process [GO:0046513]; establishment of skin barrier [GO:0061436]; fat cell differentiation [GO:0045444]; hepoxilin biosynthetic process [GO:0051122]; linoleic acid metabolic process [GO:0043651]; lipid oxidation [GO:0034440]; lipoxygenase pathway [GO:0019372]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; sensory perception of pain [GO:0019233]; sphingolipid metabolic process [GO:0006665] cytosol [GO:0005829] "hepoxilin A3 synthase activity [GO:0051120]; hydroperoxy icosatetraenoate dehydratase activity [GO:0106256]; hydroperoxy icosatetraenoate isomerase activity [GO:0106255]; intramolecular transferase activity, transferring hydroxy groups [GO:0050486]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]" 0.87621 -0.0084778 LCTPGEMVK 0 0 0 0 0 0 0 0 0 0 0 9.87163 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BYJ4 TRI34_HUMAN E3 ubiquitin-protein ligase TRIM34 (EC 2.3.2.27) (Interferon-responsive finger protein 1) (RING finger protein 21) TRIM34 IFP1 RNF21 Homo sapiens (Human) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of autophagy [GO:0010508]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein polyubiquitination [GO:0000209]; regulation of protein localization [GO:0032880]; regulation of viral entry into host cell [GO:0046596] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.46193 0.63528 LEEEEKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.08284 0 0 0 0 9.68626 0 0 0 Q9BYK8 HELZ2_HUMAN "Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-)" HELZ2 KIAA1769 PRIC285 Homo sapiens (Human) ncRNA-mediated post-transcriptional gene silencing [GO:0035194]; positive regulation of transcription by RNA polymerase II [GO:0045944] cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; P granule [GO:0043186] ATP binding [GO:0005524]; DNA binding [GO:0003677]; helicase activity [GO:0004386]; metal ion binding [GO:0046872]; nuclear receptor coactivator activity [GO:0030374]; RNA binding [GO:0003723]; RNA nuclease activity [GO:0004540] 0.95107 -1.4374 LNPSQNVAVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.9334 0 0 9.69785 0 10.1799 0 11.6109 Q9BYL1 SAM10_HUMAN Sterile alpha motif domain-containing protein 10 (SAM domain-containing protein 10) SAMD10 C20orf136 Homo sapiens (Human) transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] cytoplasmic side of plasma membrane [GO:0009898] 0.86741 0.072466 DVDATAHFSFCR 0 0 0 0 0 0 0 10.0471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BYM8 HOIL1_HUMAN RanBP-type and C3HC4-type zinc finger-containing protein 1 (EC 2.3.2.31) (HBV-associated factor 4) (Heme-oxidized IRP2 ubiquitin ligase 1) (HOIL-1) (Hepatitis B virus X-associated protein 4) (RING finger protein 54) (RING-type E3 ubiquitin transferase HOIL-1) (Ubiquitin-conjugating enzyme 7-interacting protein 3) RBCK1 C20orf18 RNF54 UBCE7IP3 XAP3 XAP4 Homo sapiens (Human) cytoplasmic sequestering of protein [GO:0051220]; defense response to bacterium [GO:0042742]; negative regulation of necroptotic process [GO:0060546]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein linear polyubiquitination [GO:0097039]; protein polyubiquitination [GO:0000209]; T cell receptor signaling pathway [GO:0050852] cytosol [GO:0005829]; LUBAC complex [GO:0071797] identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein sequestering activity [GO:0140311]; transcription coactivator activity [GO:0003713]; ubiquitin binding [GO:0043130]; ubiquitin-protein transferase activity [GO:0004842] 0.75696 0.30466 AEEMALSLTR 0 0 0 0 0 0 0 0 0 0 9.06657 0 0 0 0 0 0 0 0 0 0 0 0 9.89341 0 0 0 Q9BYN7 ZN341_HUMAN Zinc finger protein 341 ZNF341 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96918 -4.4365 CVKCVNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.72503 0 9.62311 0 0 0 0 0 0 0 0 0 0 Q9BYN8 RT26_HUMAN "Small ribosomal subunit protein mS26 (28S ribosomal protein S13, mitochondrial) (MRP-S13) (S13mt) (28S ribosomal protein S26, mitochondrial) (MRP-S26) (S26mt)" MRPS26 C20orf193 RPMS13 Homo sapiens (Human) mitochondrial translation [GO:0032543] mitochondrial inner membrane [GO:0005743]; mitochondrial small ribosomal subunit [GO:0005763]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] RNA binding [GO:0003723] 0.89901 -0.60318 AEEVQAWAQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.93278 0 0 0 0 0 0 0 0 Q9BYP7 WNK3_HUMAN Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase lysine-deficient 3) (Protein kinase with no lysine 3) WNK3 KIAA1566 PRKWNK3 Homo sapiens (Human) cell volume homeostasis [GO:0006884]; intracellular signal transduction [GO:0035556]; maintenance of blood-brain barrier [GO:0035633]; monoatomic ion homeostasis [GO:0050801]; negative regulation of apoptotic process [GO:0043066]; osmosensory signaling pathway [GO:0007231]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of ion transmembrane transporter activity [GO:0032414]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein autophosphorylation [GO:0046777]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; regulation of calcium ion import [GO:0090279]; regulation of monoatomic cation transmembrane transport [GO:1904062] adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737] ATP binding [GO:0005524]; chloride channel inhibitor activity [GO:0019869]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.88299 -0.27126 FYDSWESILKGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0058 0 0 0 0 0 0 0 0 0 0 Q9BYS8 LRRC2_HUMAN Leucine-rich repeat-containing protein 2 LRRC2 Homo sapiens (Human) 0.92065 -0.92052 FSSVPICVLR 0 0 13.0472 0 0 0 0 0 0 0 0 0 0 0 0 0 9.41443 0 0 0 9.84141 0 0 0 0 0 0 Q9BYT3 STK33_HUMAN Serine/threonine-protein kinase 33 (EC 2.7.11.1) STK33 Homo sapiens (Human) mitotic DNA damage checkpoint signaling [GO:0044773]; protein autophosphorylation [GO:0046777] cytoplasm [GO:0005737]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.78685 0.25866 CPDCSSASQK 0 0 10.0325 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BYT8 NEUL_HUMAN "Neurolysin, mitochondrial (EC 3.4.24.16) (Angiotensin-binding protein) (Microsomal endopeptidase) (MEP) (Mitochondrial oligopeptidase M) (Neurotensin endopeptidase)" NLN AGTBP KIAA1226 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; peptide metabolic process [GO:0006518]; proteolysis [GO:0006508]; regulation of gluconeogenesis [GO:0006111]; regulation of skeletal muscle fiber differentiation [GO:1902809] cytosol [GO:0005829]; extracellular region [GO:0005576]; mitochondrial intermembrane space [GO:0005758]; plasma membrane [GO:0005886] metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; peptide binding [GO:0042277] 0.91436 -0.83119 EFILNLKK 0 8.19081 0 8.50871 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BYT9 ANO3_HUMAN Anoctamin-3 (Transmembrane protein 16C) ANO3 C11orf25 TMEM16C GENX-3947 Homo sapiens (Human) calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; chloride transmembrane transport [GO:1902476]; detection of mechanical stimulus [GO:0050982]; detection of temperature stimulus [GO:0016048]; establishment of localization in cell [GO:0051649]; monoatomic ion transmembrane transport [GO:0034220] plasma membrane [GO:0005886] chloride channel activity [GO:0005254]; intracellular calcium activated chloride channel activity [GO:0005229]; phospholipid scramblase activity [GO:0017128]; protein dimerization activity [GO:0046983] 0.96966 -3.4529 DTFFSNATRSR 0 0 9.62726 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1075 0 9.63436 0 0 0 0 0 0 0 0 Q9BYV1 AGT2_HUMAN "Alanine--glyoxylate aminotransferase 2, mitochondrial (AGT 2) (EC 2.6.1.44) ((R)-3-amino-2-methylpropionate--pyruvate transaminase) (EC 2.6.1.40) (Beta-ALAAT II) (Beta-alanine-pyruvate aminotransferase) (D-AIBAT)" AGXT2 AGT2 Homo sapiens (Human) "glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]; glyoxylate catabolic process [GO:0009436]; L-alanine catabolic process, by transamination [GO:0019481]; positive regulation of nitric oxide biosynthetic process [GO:0045429]" mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] (R)-3-amino-2-methylpropionate-pyruvate transaminase activity [GO:0047305]; alanine-glyoxylate transaminase activity [GO:0008453]; pyridoxal phosphate binding [GO:0030170] 0.95006 -1.3838 ISCRPLPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3009 0 0 0 Q9BYV6 TRI55_HUMAN Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF-2) (MuRF2) (RING finger protein 29) TRIM55 MURF2 RNF29 Homo sapiens (Human) diapedesis [GO:0050904]; leukocyte migration involved in inflammatory response [GO:0002523]; macrophage migration [GO:1905517]; protein ubiquitination [GO:0016567]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleus [GO:0005634] identical protein binding [GO:0042802]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.91726 -0.85967 KSDQPMCEEHEEER 0 9.41022 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2648 0 Q9BYW2 SETD2_HUMAN Histone-lysine N-methyltransferase SETD2 (EC 2.1.1.359) (HIF-1) (Huntingtin yeast partner B) (Huntingtin-interacting protein 1) (HIP-1) (Huntingtin-interacting protein B) (Lysine N-methyltransferase 3A) (Protein-lysine N-methyltransferase SETD2) (EC 2.1.1.-) (SET domain-containing protein 2) (hSET2) (p231HBP) SETD2 HIF1 HYPB KIAA1732 KMT3A SET2 HSPC069 Homo sapiens (Human) angiogenesis [GO:0001525]; cell migration involved in vasculogenesis [GO:0035441]; coronary vasculature morphogenesis [GO:0060977]; defense response to virus [GO:0051607]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic placenta morphogenesis [GO:0060669]; endodermal cell differentiation [GO:0035987]; forebrain development [GO:0030900]; histone H3-K36 dimethylation [GO:0097676]; histone H3-K36 trimethylation [GO:0097198]; mesoderm morphogenesis [GO:0048332]; microtubule cytoskeleton organization involved in mitosis [GO:1902850]; mismatch repair [GO:0006298]; morphogenesis of a branching structure [GO:0001763]; neural tube closure [GO:0001843]; nucleosome organization [GO:0034728]; peptidyl-lysine trimethylation [GO:0018023]; pericardium development [GO:0060039]; positive regulation of autophagy [GO:0010508]; positive regulation of interferon-alpha production [GO:0032727]; regulation of cytokinesis [GO:0032465]; regulation of DNA-templated transcription [GO:0006355]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of gene expression [GO:0010468]; regulation of mRNA export from nucleus [GO:0010793]; regulation of protein localization to chromatin [GO:1905634]; response to type I interferon [GO:0034340]; stem cell development [GO:0048864]; stem cell differentiation [GO:0048863]; transcription elongation by RNA polymerase II [GO:0006368] chromosome [GO:0005694]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] alpha-tubulin binding [GO:0043014]; histone H3K36 methyltransferase activity [GO:0046975]; histone H3K36 trimethyltransferase activity [GO:0140955]; metal ion binding [GO:0046872]; protein-lysine N-methyltransferase activity [GO:0016279] 0.95983 -1.9305 EVYRIPK 10.4037 0 0 0 0 0 0 9.79755 0 0 0 0 0 0 0 0 0 0 0 0 10.4115 0 0 0 0 0 0 Q9BYX2 TBD2A_HUMAN TBC1 domain family member 2A (Armus) (Prostate antigen recognized and identified by SEREX 1) (PARIS-1) TBC1D2 PARIS1 PP8997 TBC1D2A Homo sapiens (Human) activation of GTPase activity [GO:0090630]; positive regulation of GTPase activity [GO:0043547] anchoring junction [GO:0070161]; cell junction [GO:0030054]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] cadherin binding [GO:0045296]; GTPase activator activity [GO:0005096] 0.97003 -4.1595 ADAEEGIFEIKTPSR 0 0 0 0 0 0 0 0 0 0 0 0 9.26071 0 0 0 0 0 0 10.0294 0 9.40699 0 0 0 9.19261 0 Q9BYX4 IFIH1_HUMAN Interferon-induced helicase C domain-containing protein 1 (EC 3.6.4.13) (Clinically amyopathic dermatomyositis autoantigen 140 kDa) (CADM-140 autoantigen) (Helicase with 2 CARD domains) (Helicard) (Interferon-induced with helicase C domain protein 1) (Melanoma differentiation-associated protein 5) (MDA-5) (Murabutide down-regulated protein) (RIG-I-like receptor 2) (RLR-2) (RNA helicase-DEAD box protein 116) IFIH1 MDA5 RH116 Homo sapiens (Human) antiviral innate immune response [GO:0140374]; cellular response to exogenous dsRNA [GO:0071360]; cellular response to virus [GO:0098586]; cytosolic pattern recognition receptor signaling pathway [GO:0002753]; defense response to virus [GO:0051607]; detection of virus [GO:0009597]; innate immune response [GO:0045087]; MDA-5 signaling pathway [GO:0039530]; negative regulation of viral genome replication [GO:0045071]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of response to cytokine stimulus [GO:0060760]; positive regulation of tumor necrosis factor production [GO:0032760]; protein complex oligomerization [GO:0051259]; protein sumoylation [GO:0016925]; regulation of type III interferon production [GO:0034344]; response to virus [GO:0009615]; type I interferon-mediated signaling pathway [GO:0060337] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634] adenyl ribonucleotide binding [GO:0032559]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA binding [GO:0003677]; double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; pattern recognition receptor activity [GO:0038187]; purine ribonucleoside triphosphate binding [GO:0035639]; ribonucleoprotein complex binding [GO:0043021]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; zinc ion binding [GO:0008270] 0.95504 -1.5366 ELYIVRENKALQK 13.7716 0 13.9611 0 0 0 10.4432 12.9832 0 10.7536 0 8.3773 10.5504 11.4438 0 0 0 0 0 0 9.56352 0 0 0 10.9124 0 0 Q9BYZ2 LDH6B_HUMAN L-lactate dehydrogenase A-like 6B (EC 1.1.1.27) LDHAL6B LDHAL6 LDHL Homo sapiens (Human) lactate metabolic process [GO:0006089]; pyruvate metabolic process [GO:0006090] cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; oxidoreductase complex [GO:1990204] L-lactate dehydrogenase activity [GO:0004459] 0.95976 -1.9758 GETRLNLVQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1982 0 0 0 0 0 0 0 0 0 0 0 0 Q9BZ19 ANR60_HUMAN Ankyrin repeat domain-containing protein 60 ANKRD60 C20orf86 Homo sapiens (Human) 0.84335 0.13985 AAAGAGGAR 0 0 0 0 0 0 7.90412 8.84229 0 0 0 9.04745 0 0 0 0 0 0 0 8.70155 10.0039 10.855 0 0 0 0 0 Q9BZ23 PANK2_HUMAN "Pantothenate kinase 2, mitochondrial (hPanK2) (EC 2.7.1.33) (Pantothenic acid kinase 2) [Cleaved into: Pantothenate kinase 2, mitochondrial intermediate form (iPanK2); Pantothenate kinase 2, mitochondrial mature form (mPanK2)]" PANK2 C20orf48 Homo sapiens (Human) aerobic respiration [GO:0009060]; angiogenesis [GO:0001525]; coenzyme A biosynthetic process [GO:0015937]; mitochondrion morphogenesis [GO:0070584]; pantothenate metabolic process [GO:0015939]; phosphorylation [GO:0016310]; regulation of bile acid metabolic process [GO:1904251]; regulation of fatty acid metabolic process [GO:0019217]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of triglyceride metabolic process [GO:0090207]; spermatid development [GO:0007286] cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634] ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594] 0.96178 -2.5603 DLTLCGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.36151 0 0 Q9BZ29 DOCK9_HUMAN Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin-1) (Zizimin-1) DOCK9 KIAA1058 ZIZ1 Homo sapiens (Human) positive regulation of GTPase activity [GO:0043547]; small GTPase mediated signal transduction [GO:0007264] cytosol [GO:0005829]; endomembrane system [GO:0012505]; membrane [GO:0016020] cadherin binding [GO:0045296]; guanyl-nucleotide exchange factor activity [GO:0005085] 0.9598 -1.7208 DSDEEDSQPLK 9.3386 0 0 10.7248 0 9.6728 0 0 9.65939 0 0 0 0 10.0776 0 0 0 11.4242 11.5549 0 0 8.32908 10.8471 9.36807 9.22882 9.52123 0 Q9BZ67 FRMD8_HUMAN FERM domain-containing protein 8 (Band4.1 inhibitor LRP interactor) (Bili) (iRhom tail-associated protein) (iTAP) FRMD8 FKSG44 Homo sapiens (Human) negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of tumor necrosis factor production [GO:0032760]; protein localization to plasma membrane [GO:0072659] centriolar satellite [GO:0034451]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] 0.62715 0.41131 GNVLAAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.5328 0 0 0 0 0 0 0 0 0 0 0 Q9BZ72 PITM2_HUMAN "Membrane-associated phosphatidylinositol transfer protein 2 (Phosphatidylinositol transfer protein, membrane-associated 2) (PITPnm 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3)" PITPNM2 KIAA1457 NIR3 Homo sapiens (Human) phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; membrane [GO:0016020] calcium ion binding [GO:0005509]; phosphatidylcholine binding [GO:0031210]; phosphatidylcholine transporter activity [GO:0008525]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol transfer activity [GO:0008526]; receptor tyrosine kinase binding [GO:0030971] 0.96161 -2.0766 DITKWSSNDLMDK 0 0 0 0 0 0 0 9.17981 0 0 0 9.18244 0 0 0 0 0 0 0 0 0 10.5259 0 0 0 0 0 Q9BZ76 CNTP3_HUMAN Contactin-associated protein-like 3 (Cell recognition molecule Caspr3) CNTNAP3 CASPR3 KIAA1714 Homo sapiens (Human) cell adhesion [GO:0007155]; cell recognition [GO:0008037] extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886] 0.91529 -0.79463 DVTLTREMITLSFR 10.0723 0 0 0 0 0 0 8.68377 0 0 0 0 0 0 0 0 0 0 0 0 9.40557 0 0 0 0 0 0 Q9BZ81 MAGB5_HUMAN Melanoma-associated antigen B5 (Cancer/testis antigen 3.3) (CT3.3) (MAGE-B5 antigen) MAGEB5 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] 0.94127 -1.3144 ILKEDMLK 0 0 0 0 0 0 0 0 0 0 0 0 9.28526 0 0 0 0 11.2505 0 0 0 0 0 0 0 0 0 Q9BZ95 NSD3_HUMAN Histone-lysine N-methyltransferase NSD3 (EC 2.1.1.370) (EC 2.1.1.371) (Nuclear SET domain-containing protein 3) (Protein whistle) (WHSC1-like 1 isoform 9 with methyltransferase activity to lysine) (Wolf-Hirschhorn syndrome candidate 1-like protein 1) (WHSC1-like protein 1) NSD3 WHSC1L1 DC28 Homo sapiens (Human) methylation [GO:0032259]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription [GO:0006355] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] histone H3K27 dimethyltransferase activity [GO:0140952]; histone H3K36 methyltransferase activity [GO:0046975]; histone H3K4 dimethyltransferase activity [GO:0140946]; metal ion binding [GO:0046872]; transcription regulator activator activity [GO:0140537] 0.88506 -0.22574 DRIIDAGPKGNYSR 11.0325 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1143 0 10.2786 0 Q9BZ98 TTY12_HUMAN Putative transcript Y 12 protein TTTY12 TTY12 Homo sapiens (Human) 0.95451 -1.5106 IDPETRHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.79084 0 0 9.90218 0 0 0 0 0 Q9BZB8 CPEB1_HUMAN Cytoplasmic polyadenylation element-binding protein 1 (CPE-BP1) (CPE-binding protein 1) (h-CPEB) (hCPEB-1) CPEB1 CPEB Homo sapiens (Human) cellular response to amino acid stimulus [GO:0071230]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; mRNA processing [GO:0006397]; negative regulation of cytoplasmic translation [GO:2000766]; positive regulation of mRNA polyadenylation [GO:1900365] cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; membrane [GO:0016020]; messenger ribonucleoprotein complex [GO:1990124]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; postsynaptic density [GO:0014069]; synapse [GO:0045202] "metal ion binding [GO:0046872]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA regulatory element binding translation repressor activity [GO:0000900]; ribosome binding [GO:0043022]; translation factor activity, RNA binding [GO:0008135]" 0.93311 -1.2787 HPRCPPKGNMPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3439 0 Q9BZC7 ABCA2_HUMAN ATP-binding cassette sub-family A member 2 (EC 7.6.2.-) (ATP-binding cassette transporter 2) (ATP-binding cassette 2) ABCA2 ABC2 KIAA1062 Homo sapiens (Human) central nervous system myelin formation [GO:0032289]; ceramide translocation [GO:0099040]; cholesterol homeostasis [GO:0042632]; ganglioside metabolic process [GO:0001573]; glycosphingolipid metabolic process [GO:0006687]; intracellular sphingolipid homeostasis [GO:0090156]; lipid metabolic process [GO:0006629]; lipid transport [GO:0006869]; locomotory behavior [GO:0007626]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of intracellular cholesterol transport [GO:0032384]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of phospholipid biosynthetic process [GO:0071072]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of sphingolipid biosynthetic process [GO:0090155]; negative regulation of steroid metabolic process [GO:0045939]; positive regulation of amyloid precursor protein biosynthetic process [GO:0042986]; positive regulation of amyloid precursor protein catabolic process [GO:1902993]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; regulation of intracellular cholesterol transport [GO:0032383]; regulation of post-translational protein modification [GO:1901873]; regulation of protein glycosylation [GO:0060049]; regulation of protein localization to cell periphery [GO:1904375]; regulation of protein localization to cell surface [GO:2000008]; regulation of steroid metabolic process [GO:0019218]; response to cholesterol [GO:0070723]; response to steroid hormone [GO:0048545]; response to xenobiotic stimulus [GO:0009410]; sphingomyelin metabolic process [GO:0006684]; sphingosine biosynthetic process [GO:0046512]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104] ATP-binding cassette (ABC) transporter complex [GO:0043190]; cytoplasmic vesicle [GO:0031410]; endosome [GO:0005768]; endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; plasma membrane [GO:0005886] ABC-type transporter activity [GO:0140359]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]; ceramide floppase activity [GO:0099038]; endopeptidase regulator activity [GO:0061135]; lipid transporter activity [GO:0005319]; nucleotide binding [GO:0000166] 0.93239 -1.2677 AQLSFNTDTLC 0 0 0 0 0 0 10.6478 0 0 0 0 0 0 9.5562 0 0 0 0 0 0 0 8.81099 0 0 0 0 0 Q9BZD4 NUF2_HUMAN Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1) NUF2 CDCA1 NUF2R Homo sapiens (Human) attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; attachment of spindle microtubules to kinetochore [GO:0008608]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; kinetochore organization [GO:0051383]; meiotic chromosome segregation [GO:0045132]; mitotic spindle assembly checkpoint signaling [GO:0007094]; mitotic spindle organization [GO:0007052] "chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; kinetochore [GO:0000776]; membrane [GO:0016020]; Ndc80 complex [GO:0031262]; nucleoplasm [GO:0005654]" protein-containing complex binding [GO:0044877] 0.96998 -5.2971 IVDSPEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4184 0 11.1828 9.60548 0 0 0 10.4224 Q9BZE0 GLIS2_HUMAN Zinc finger protein GLIS2 (GLI-similar 2) (Neuronal Krueppel-like protein) GLIS2 NKL Homo sapiens (Human) cell differentiation involved in kidney development [GO:0061005]; central nervous system development [GO:0007417]; hematopoietic stem cell homeostasis [GO:0061484]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of transcription by RNA polymerase II [GO:0045944] cytoplasm [GO:0005737]; non-motile cilium [GO:0097730]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]" 0.83476 0.18656 ALGMEGHK 0 0 0 0 0 0 0 0 0 0 0 8.90394 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BZE2 PUS3_HUMAN tRNA pseudouridine(38/39) synthase (EC 5.4.99.45) (tRNA pseudouridine synthase 3) (tRNA pseudouridylate synthase 3) (tRNA-uridine isomerase 3) PUS3 FKSG32 Homo sapiens (Human) mRNA pseudouridine synthesis [GO:1990481]; tRNA modification [GO:0006400]; tRNA pseudouridine synthesis [GO:0031119] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723]; tRNA pseudouridine synthase activity [GO:0106029] 0.88988 -0.45944 ADLDIVTMDYAAQKYVGTHDFR 0 12.0888 12.676 0 0 0 12.279 0 9.94742 13.6221 13.4153 0 0 0 0 11.2265 0 0 0 0 0 0 0 0 0 0 0 Q9BZE4 GTPB4_HUMAN GTP-binding protein 4 (Chronic renal failure gene protein) (GTP-binding protein NGB) (Nucleolar GTP-binding protein 1) GTPBP4 CRFG NOG1 Homo sapiens (Human) "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of collagen binding [GO:0033342]; negative regulation of DNA replication [GO:0008156]; negative regulation of protein ubiquitination [GO:0031397]; osteoblast differentiation [GO:0001649]; protein stabilization [GO:0050821]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; ribosomal large subunit biogenesis [GO:0042273]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; preribosome binding [GO:1990275]; RNA binding [GO:0003723] 0.96983 -3.2608 DVKMVKK 0 0 0 9.42465 0 0 0 10.667 0 9.18767 9.2466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BZE9 ASPC1_HUMAN Tether containing UBX domain for GLUT4 (Alveolar soft part sarcoma chromosomal region candidate gene 1 protein) (Alveolar soft part sarcoma locus) (Renal papillary cell carcinoma protein 17) (UBX domain-containing protein 9) ASPSCR1 ASPL RCC17 TUG UBXD9 UBXN9 Homo sapiens (Human) glucose homeostasis [GO:0042593]; intracellular protein transport [GO:0006886]; positive regulation of protein modification process [GO:0031401]; regulation of glucose import [GO:0046324] cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506] 0.91981 -1.1426 SLGKVPK 0 0 0 0 0 0 9.29902 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BZF1 OSBL8_HUMAN Oxysterol-binding protein-related protein 8 (ORP-8) (OSBP-related protein 8) OSBPL8 KIAA1451 ORP8 OSBP10 Homo sapiens (Human) activation of protein kinase B activity [GO:0032148]; fat cell differentiation [GO:0045444]; negative regulation of cell migration [GO:0030336]; negative regulation of sequestering of triglyceride [GO:0010891]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid transport [GO:0015914]; positive regulation of glucose import [GO:0046326]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of protein kinase B signaling [GO:0051897]; protein localization to nuclear pore [GO:0090204] cortical endoplasmic reticulum [GO:0032541]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nuclear membrane [GO:0031965] cholesterol binding [GO:0015485]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylserine binding [GO:0001786]; phosphatidylserine transfer activity [GO:0140343]; phospholipid transporter activity [GO:0005548]; sterol transporter activity [GO:0015248] 0.96925 -3.3959 LYNGSEKDSSTSSK 0 0 0 0 0 0 0 0 0 0 0 11.4605 0 0 9.82671 10.7095 0 0 0 0 0 0 0 0 0 0 10.6339 Q9BZF2 OSBL7_HUMAN Oxysterol-binding protein-related protein 7 (ORP-7) (OSBP-related protein 7) OSBPL7 ORP7 Homo sapiens (Human) bile acid biosynthetic process [GO:0006699]; cellular response to cholesterol [GO:0071397]; positive regulation of proteasomal protein catabolic process [GO:1901800]; regulation of autophagy [GO:0010506] autophagosome [GO:0005776]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; perinuclear endoplasmic reticulum [GO:0097038]; plasma membrane [GO:0005886] cholesterol binding [GO:0015485]; sterol transporter activity [GO:0015248] 0.96416 -2.2105 GLPPTDYAHLQRSFWALAQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.3975 0 Q9BZF9 UACA_HUMAN Uveal autoantigen with coiled-coil domains and ankyrin repeats UACA KIAA1561 Homo sapiens (Human) negative regulation of NIK/NF-kappaB signaling [GO:1901223]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280] cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] actin binding [GO:0003779] 0.92147 -1.1268 EQQTVTK 0 0 10.3392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.18527 0 0 0 0 0 0 8.38694 0 0 Q9BZG2 PPAT_HUMAN Testicular acid phosphatase (EC 3.1.3.2) (Acid phosphatase 4) ACP4 ACPT Homo sapiens (Human) lysosome organization [GO:0007040]; negative regulation of ERBB4 signaling pathway [GO:0120154]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein processing [GO:0010955]; odontogenesis [GO:0042476]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; regulation of neuronal synaptic plasticity [GO:0048168] lysosome [GO:0005764]; postsynaptic membrane [GO:0045211] acid phosphatase activity [GO:0003993]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971] 0.88282 -0.10493 REEVYIRSTDFDR 0 0 0 0 0 0 0 0 0 9.2097 0 0 0 0 0 8.54102 0 0 0 0 0 0 0 0 0 0 0 Q9BZG8 DPH1_HUMAN 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 (EC 2.5.1.108) (Diphthamide biosynthesis protein 1) (Diphtheria toxin resistance protein 1) (Ovarian cancer-associated gene 1 protein) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1) DPH1 DPH2L DPH2L1 OVCA1 Homo sapiens (Human) peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183] cell junction [GO:0030054]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991] "2-(3-amino-3-carboxypropyl)histidine synthase activity [GO:0090560]; 4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]" 0.84222 0.17702 ILEHLESR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2635 0 0 0 0 0 0 0 0 0 0 0 Q9BZI1 IRX2_HUMAN Iroquois-class homeodomain protein IRX-2 (Homeodomain protein IRXA2) (Iroquois homeobox protein 2) IRX2 IRXA2 Homo sapiens (Human) cell development [GO:0048468]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; proximal/distal pattern formation involved in metanephric nephron development [GO:0072272]; regulation of transcription by RNA polymerase II [GO:0006357]; specification of loop of Henle identity [GO:0072086] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]" 0.48569 0.6219 MTLTQVSTWFANAR 0 0 0 0 0 0 0 0 0 0 0 9.56459 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BZI7 REN3B_HUMAN Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (Up-frameshift suppressor 3 homolog on chromosome X) (hUpf3p-X) UPF3B RENT3B UPF3X Homo sapiens (Human) "brain development [GO:0007420]; mRNA transport [GO:0051028]; neuron projection development [GO:0031175]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of translation [GO:0045727]" centriolar satellite [GO:0034451]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; exon-exon junction complex [GO:0035145]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] mRNA binding [GO:0003729]; RNA binding [GO:0003723] 0.88568 -0.36788 DYRERER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.01475 0 0 Q9BZJ0 CRNL1_HUMAN Crooked neck-like protein 1 (Crooked neck homolog) (hCrn) CRNKL1 CRN CGI-201 MSTP021 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; spliceosomal complex assembly [GO:0000245]" catalytic step 2 spliceosome [GO:0071013]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; post-mRNA release spliceosomal complex [GO:0071014]; Prp19 complex [GO:0000974]; spliceosomal complex [GO:0005681]; U2-type catalytic step 2 spliceosome [GO:0071007] RNA binding [GO:0003723] 0.88691 -0.34684 FQYEEEVK 0 0 0 0 0 0 0 0 0 0 0 0 12.2727 9.11202 0 0 0 0 0 0 10.4065 0 0 0 0 0 0 Q9BZJ4 S2539_HUMAN Probable mitochondrial glutathione transporter SLC25A39 (Solute carrier family 25 member 39) SLC25A39 CGI-69 PRO2163 Homo sapiens (Human) glutathione import into mitochondrion [GO:0160007]; heme biosynthetic process [GO:0006783]; mitochondrial transmembrane transport [GO:1990542] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] 0.8848 -0.33422 ELGACVR 0 0 0 0 0 0 0 0 0 0 9.32026 0 0 0 0 0 0 0 0 0 0 10.3099 0 0 0 0 0 Q9BZL4 PP12C_HUMAN Protein phosphatase 1 regulatory subunit 12C (Protein phosphatase 1 myosin-binding subunit of 85 kDa) (Protein phosphatase 1 myosin-binding subunit p85) PPP1R12C LENG3 MBS85 Homo sapiens (Human) signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856] enzyme inhibitor activity [GO:0004857]; phosphatase regulator activity [GO:0019208]; protein kinase binding [GO:0019901] 0.85005 0.11743 ISLQDLSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.96168 0 0 0 0 Q9BZM6 ULBP1_HUMAN UL16-binding protein 1 (ALCAN-beta) (NKG2D ligand 1) (N2DL-1) (NKG2DL1) (Retinoic acid early transcript 1I) ULBP1 N2DL1 RAET1I Homo sapiens (Human) "antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent [GO:0002486]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; immune response [GO:0006955]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; positive regulation of T cell mediated cytotoxicity [GO:0001916]" cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] natural killer cell lectin-like receptor binding [GO:0046703] 0.83543 0.19081 DVTMFFQK 0 0 0 0 0 0 0 0 0 0 9.52448 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BZP3 CR002_HUMAN Putative uncharacterized protein encoded by LINC00470 LINC00470 C18orf2 Homo sapiens (Human) 0.89855 -0.56805 VGAAATSR 0 0 0 0 0 0 0 0 0 9.30054 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BZP6 CHIA_HUMAN Acidic mammalian chitinase (AMCase) (EC 3.2.1.14) (Lung-specific protein TSA1902) CHIA Homo sapiens (Human) apoptotic process [GO:0006915]; chitin catabolic process [GO:0006032]; chitin metabolic process [GO:0006030]; immune system process [GO:0002376]; polysaccharide catabolic process [GO:0000272]; polysaccharide digestion [GO:0044245]; positive regulation of chemokine production [GO:0032722]; production of molecular mediator involved in inflammatory response [GO:0002532] cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615] chitin binding [GO:0008061]; chitinase activity [GO:0004568]; kinase binding [GO:0019900] 0.0083102 2.196 QTFITSVIK 11.4968 11.4911 11.3937 9.61062 9.85342 9.70297 11.0935 11.2064 11.3003 12.0385 11.6573 10.9504 10.7767 10.8277 10.6959 10.9519 11.1573 11.3713 0 0 0 0 0 0 0 0 0 Q9BZQ6 EDEM3_HUMAN "ER degradation-enhancing alpha-mannosidase-like protein 3 (EC 3.2.1.113) (Alpha-1,2-mannosidase EDEM3)" EDEM3 C1orf22 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; endoplasmic reticulum mannose trimming [GO:1904380]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; protein glycosylation [GO:0006486]; response to unfolded protein [GO:0006986] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum quality control compartment [GO:0044322]; membrane [GO:0016020] "calcium ion binding [GO:0005509]; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [GO:0004571]" 0.68193 0.39073 TKEFEDAVRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.09003 0 0 0 0 0 0 0 0 0 0 0 Q9BZQ8 NIBA1_HUMAN Protein Niban 1 (Cell growth-inhibiting gene 39 protein) (Protein FAM129A) NIBAN1 C1orf24 FAM129A NIBAN GIG39 Homo sapiens (Human) negative regulation of protein phosphorylation [GO:0001933]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of translation [GO:0045727]; response to endoplasmic reticulum stress [GO:0034976] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886] 0.92513 -0.98473 ALASTCKPELQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.7413 9.87593 0 9.54682 9.60403 11.9681 0 0 Q9BZR6 RTN4R_HUMAN Reticulon-4 receptor (Nogo receptor) (NgR) (Nogo-66 receptor) RTN4R NOGOR UNQ330/PRO526 Homo sapiens (Human) axonogenesis [GO:0007409]; cell surface receptor signaling pathway [GO:0007166]; corpus callosum development [GO:0022038]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of neuron projection development [GO:0010977]; neuronal signal transduction [GO:0023041]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Rho protein signal transduction [GO:0035025] axonal growth cone [GO:0044295]; cell surface [GO:0009986]; dendritic shaft [GO:0043198]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793] chondroitin sulfate binding [GO:0035374]; ganglioside GM1 binding [GO:1905573]; ganglioside GT1b binding [GO:1905576]; heparin binding [GO:0008201]; neuregulin receptor activity [GO:0038131]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023] 0.67618 0.39371 ASAGGSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.12309 0 0 0 0 Q9BZR8 B2L14_HUMAN Apoptosis facilitator Bcl-2-like protein 14 (Bcl2-L-14) (Apoptosis regulator Bcl-G) BCL2L14 BCLG Homo sapiens (Human) apoptotic process [GO:0006915]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; regulation of extrinsic apoptotic signaling pathway [GO:2001236] cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular organelle [GO:0043229]; membrane [GO:0016020] protein kinase binding [GO:0019901] 0.73576 0.32816 LTAIDNHPMNR 0 0 11.0697 0 0 0 0 10.8548 0 0 0 0 0 9.54108 0 0 0 0 0 0 0 0 0 9.60164 0 0 0 Q9BZS1 FOXP3_HUMAN "Forkhead box protein P3 (Scurfin) [Cleaved into: Forkhead box protein P3, C-terminally processed; Forkhead box protein P3 41 kDa form]" FOXP3 IPEX JM2 Homo sapiens (Human) "B cell homeostasis [GO:0001782]; CD4-positive, alpha-beta T cell proliferation [GO:0035739]; CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment [GO:0002362]; chromatin remodeling [GO:0006338]; establishment of endothelial blood-brain barrier [GO:0014045]; immature T cell proliferation in thymus [GO:0033080]; inflammatory response [GO:0006954]; isotype switching to IgE isotypes [GO:0048289]; myeloid cell homeostasis [GO:0002262]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chronic inflammatory response [GO:0002677]; negative regulation of CREB transcription factor activity [GO:0032792]; negative regulation of cytokine production [GO:0001818]; negative regulation of defense response to virus [GO:0050687]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of histone deacetylation [GO:0031064]; negative regulation of immune response [GO:0050777]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of interleukin-4 production [GO:0032713]; negative regulation of interleukin-5 production [GO:0032714]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of isotype switching to IgE isotypes [GO:0048294]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell cytokine production [GO:0002725]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 17 cell differentiation [GO:2000320]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation [GO:0032831]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of histone acetylation [GO:0035066]; positive regulation of immature T cell proliferation in thymus [GO:0033092]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peripheral T cell tolerance induction [GO:0002851]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of T cell anergy [GO:0002669]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta1 production [GO:0032914]; regulation of DNA-templated transcription [GO:0006355]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of T cell anergy [GO:0002667]; regulation of transcription by RNA polymerase II [GO:0006357]; regulatory T cell differentiation [GO:0045066]; response to lipopolysaccharide [GO:0032496]; response to radiation [GO:0009314]; response to rapamycin [GO:1901355]; response to virus [GO:0009615]; T cell activation [GO:0042110]; T cell anergy [GO:0002870]; T cell homeostasis [GO:0043029]; T cell mediated immunity [GO:0002456]; T cell receptor signaling pathway [GO:0050852]; tolerance induction to self antigen [GO:0002513]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta1 production [GO:0032905]" chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] "DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; NFAT protein binding [GO:0051525]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription corepressor activity [GO:0003714]" 0.94824 -1.362 GAVWTVDELEFRKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4772 0 0 0 0 0 0 0 0 0 Q9BZV1 UBXN6_HUMAN UBX domain-containing protein 6 (UBX domain-containing protein 1) UBXN6 UBXD1 UBXDC2 Homo sapiens (Human) endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; macroautophagy [GO:0016236] cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] 0.88863 -0.43652 KDQRDACIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.36942 0 0 0 0 0 0 0 0 0 0 Q9BZV3 IMPG2_HUMAN Interphotoreceptor matrix proteoglycan 2 (Interphotoreceptor matrix proteoglycan of 200 kDa) (IPM 200) (Sialoprotein associated with cones and rods proteoglycan) (Spacrcan) IMPG2 IPM200 Homo sapiens (Human) extracellular matrix organization [GO:0030198]; protein localization [GO:0008104]; retina morphogenesis in camera-type eye [GO:0060042]; visual perception [GO:0007601] cell projection [GO:0042995]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; interphotoreceptor matrix [GO:0033165]; membrane [GO:0016020]; receptor complex [GO:0043235] extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; hyaluronic acid binding [GO:0005540] 0.96911 -7.1157 QMYESSELSREEIQERMR 0 0 13.4124 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.51041 0 9.61405 Q9BZW7 TSG10_HUMAN Testis-specific gene 10 protein (Testis development protein NYD-SP7) TSGA10 CEP4L Homo sapiens (Human) spermatogenesis [GO:0007283] centriole [GO:0005814]; cytoplasm [GO:0005737]; motile cilium [GO:0031514] 0.95947 -1.7564 EKECLQACLDKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.41642 9.58808 0 0 Q9BZW8 CD244_HUMAN Natural killer cell receptor 2B4 (NK cell activation-inducing ligand) (NAIL) (NK cell type I receptor protein 2B4) (NKR2B4) (h2B4) (SLAM family member 4) (SLAMF4) (Signaling lymphocytic activation molecule 4) (CD antigen CD244) CD244 2B4 Homo sapiens (Human) adaptive immune response [GO:0002250]; innate immune response [GO:0045087]; natural killer cell activation involved in immune response [GO:0002323]; positive regulation of granzyme B production [GO:0071663]; positive regulation of inositol phosphate biosynthetic process [GO:0060732]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of type II interferon production [GO:0032729]; signal transduction [GO:0007165] external side of plasma membrane [GO:0009897]; plasma membrane [GO:0005886] MHC class I protein binding [GO:0042288]; signaling receptor activity [GO:0038023] 0.932 -1.2564 AQNPARLSR 10.4642 10.5317 0 0 0 0 0 10.7801 10.6544 10.2085 10.078 10.6174 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9BZX2 UCK2_HUMAN Uridine-cytidine kinase 2 (UCK 2) (EC 2.7.1.48) (Cytidine monophosphokinase 2) (Testis-specific protein TSA903) (Uridine monophosphokinase 2) UCK2 UMPK Homo sapiens (Human) CTP salvage [GO:0044211]; phosphorylation [GO:0016310]; UMP salvage [GO:0044206] cytoplasm [GO:0005737]; cytosol [GO:0005829] ATP binding [GO:0005524]; cytidine kinase activity [GO:0043771]; identical protein binding [GO:0042802]; uridine kinase activity [GO:0004849] 0.8489 0.12481 GQFNFDHPDAFDNELILK 0 0 0 0 0 0 0 0 0 0 0 10.4399 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9C000 NLRP1_HUMAN "NACHT, LRR and PYD domains-containing protein 1 (EC 3.4.-.-) (EC 3.6.4.-) (Caspase recruitment domain-containing protein 7) (Death effector filament-forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) [Cleaved into: NACHT, LRR and PYD domains-containing protein 1, C-terminus (NLRP1-CT); NACHT, LRR and PYD domains-containing protein 1, N-terminus (NLRP1-NT)]" NLRP1 CARD7 DEFCAP KIAA0926 NAC NALP1 Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; antiviral innate immune response [GO:0140374]; apoptotic process [GO:0006915]; cellular response to UV-B [GO:0071493]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; inflammatory response [GO:0006954]; neuron apoptotic process [GO:0051402]; NLRP1 inflammasome complex assembly [GO:1904784]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; protein homooligomerization [GO:0051260]; pyroptosis [GO:0070269]; regulation of apoptotic process [GO:0042981]; regulation of inflammatory response [GO:0050727]; response to muramyl dipeptide [GO:0032495]; self proteolysis [GO:0097264]; stress-activated protein kinase signaling cascade [GO:0031098] canonical inflammasome complex [GO:0061702]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; NLRP1 inflammasome complex [GO:0072558]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; cysteine-type endopeptidase activator activity [GO:0140608]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; double-stranded DNA binding [GO:0003690]; double-stranded RNA binding [GO:0003725]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; molecular condensate scaffold activity [GO:0140693]; molecular function activator activity [GO:0140677]; pattern recognition receptor activity [GO:0038187]; peptidase activity [GO:0008233]; protein domain specific binding [GO:0019904]; protein self-association [GO:0043621]; signaling adaptor activity [GO:0035591]; signaling receptor activator activity [GO:0030546] 0.96949 -4.1173 AGGAWGR 0 0 0 0 0 0 0 0 0 0 9.28263 8.56335 0 0 0 0 0 0 0 9.24441 0 0 0 0 0 0 0 Q9C002 NMES1_HUMAN Normal mucosa of esophagus-specific gene 1 protein (Protein FOAP-11) NMES1 C15orf48 Homo sapiens (Human) response to bacterium [GO:0009617] mitochondrial respiratory chain complex IV [GO:0005751]; nucleus [GO:0005634] 0.91464 -0.83119 TDVILDRK 12.0073 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9C004 SPY4_HUMAN Protein sprouty homolog 4 (Spry-4) SPRY4 Homo sapiens (Human) animal organ development [GO:0048513]; cellular response to leukemia inhibitory factor [GO:1990830]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025] cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; ruffle membrane [GO:0032587] protein kinase inhibitor activity [GO:0004860] 0.91421 -0.77852 HFLLCEACGKCKCK 10.3725 9.95462 9.99025 9.97842 9.9993 9.80373 9.96809 0 10.1347 10.3015 10.4443 10.3613 0 10.1346 0 0 10.1347 10.0105 0 0 0 0 0 0 10.5106 0 10.0646 Q9C009 FOXQ1_HUMAN Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1) FOXQ1 HFH1 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; hair follicle morphogenesis [GO:0031069]; negative regulation of neuron apoptotic process [GO:0043524]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.91433 -0.82663 KLEVFVPR 0 0 0 0 0 0 0 0 0 0 11.9151 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9C019 TRI15_HUMAN E3 ubiquitin-protein ligase TRIM15 (EC 2.3.2.27) (RING finger protein 93) (Zinc finger protein 178) (Zinc finger protein B7) TRIM15 RNF93 ZNF178 ZNFB7 Homo sapiens (Human) innate immune response [GO:0045087]; mesodermal cell fate determination [GO:0007500]; negative regulation of intracellular transport of viral material [GO:1901253]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of RIG-I signaling pathway [GO:1900246]; positive regulation of type I interferon production [GO:0032481]; protein ubiquitination [GO:0016567]; suppression of viral release by host [GO:0044790] cytoplasm [GO:0005737]; focal adhesion [GO:0005925]; nucleus [GO:0005634] molecular sequestering activity [GO:0140313]; transcription coactivator activity [GO:0003713]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.54786 0.5667 ILTLPEMMR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4746 8.90454 9.98783 0 0 0 0 10.1045 Q9C029 TRIM7_HUMAN E3 ubiquitin-protein ligase TRIM7 (EC 2.3.2.27) (Glycogenin-interacting protein) (RING finger protein 90) (Tripartite motif-containing protein 7) TRIM7 GNIP RNF90 Homo sapiens (Human) antiviral innate immune response [GO:0140374]; protein ubiquitination [GO:0016567] cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634] ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.86273 0.087684 DGWAFGVARESVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.00251 0 0 0 9.33646 0 0 9.07957 0 0 0 0 0 Q9C030 TRIM6_HUMAN Tripartite motif-containing protein 6 (EC 2.3.2.27) (RING finger protein 89) (RING-type E3 ubiquitin transferase TRIM6) TRIM6 RNF89 Homo sapiens (Human) antiviral innate immune response [GO:0140374]; cellular response to interferon-beta [GO:0035458]; cellular response to virus [GO:0098586]; free ubiquitin chain polymerization [GO:0010994]; innate immune response [GO:0045087]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of viral genome replication [GO:0045071]; positive regulation of autophagy [GO:0010508]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; regulation of protein localization [GO:0032880]; regulation of viral entry into host cell [GO:0046596]; response to lipopolysaccharide [GO:0032496] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654] DNA-binding transcription factor binding [GO:0140297]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein-macromolecule adaptor activity [GO:0030674]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.95895 -1.7142 ELISDLER 11.0249 0 0 0 0 0 0 0 11.2312 0 0 0 0 0 10.6322 0 0 0 0 0 0 0 0 0 0 0 0 Q9C035 TRIM5_HUMAN Tripartite motif-containing protein 5 (EC 2.3.2.27) (RING finger protein 88) (RING-type E3 ubiquitin transferase TRIM5) TRIM5 RNF88 Homo sapiens (Human) activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of autophagy [GO:0010508]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; regulation of lipopolysaccharide-mediated signaling pathway [GO:0031664]; regulation of protein localization [GO:0032880]; regulation of viral entry into host cell [GO:0046596]; suppression of viral release by host [GO:0044790] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932] identical protein binding [GO:0042802]; pattern recognition receptor activity [GO:0038187]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein-macromolecule adaptor activity [GO:0030674]; transcription coactivator activity [GO:0003713]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.22222 0.87957 KPETFPK 0 0 0 0 0 0 0 0 0 9.05151 9.0993 9.06937 9.64221 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9C037 TRIM4_HUMAN E3 ubiquitin-protein ligase TRIM4 (EC 2.3.2.27) (RING finger protein 87) (RING-type E3 ubiquitin transferase TRIM4) (Tripartite motif-containing protein 4) TRIM4 RNF87 Homo sapiens (Human) innate immune response [GO:0045087]; protein ubiquitination [GO:0016567]; regulation of gene expression [GO:0010468] cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886] identical protein binding [GO:0042802]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.96772 -2.7851 LNQTIASLK 0 0 0 0 0 0 0 11.1436 0 0 0 0 0 0 0 0 0 9.48593 0 0 0 0 0 0 0 0 0 Q9C056 NKX62_HUMAN Homeobox protein Nkx-6.2 (Homeobox protein NK-6 homolog B) NKX6-2 GTX NKX6B Homo sapiens (Human) cell differentiation [GO:0030154]; central nervous system myelination [GO:0022010]; negative regulation of cell fate commitment [GO:0010454]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of oligodendrocyte differentiation [GO:0048715]; neuromuscular process controlling balance [GO:0050885]; neuron fate commitment [GO:0048663]; pancreatic A cell differentiation [GO:0003310]; positive regulation of cell fate commitment [GO:0010455]; positive regulation of oligodendrocyte differentiation [GO:0048714]; regulation of DNA-templated transcription [GO:0006355]; regulation of myelination [GO:0031641]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.95312 -1.4845 LAGPAPAGGVLDK 0 0 0 0 0 0 0 0 0 0 0 0 10.1731 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9C073 F117A_HUMAN Protein FAM117A (C/EBP-induced protein) FAM117A Homo sapiens (Human) 0.9635 -2.2317 AGAAAGGR 0 10.5408 10.8532 0 0 0 9.51564 9.74702 9.56035 0 11.1266 0 0 0 0 0 0 0 0 0 0 0 9.88596 0 0 0 0 Q9C075 K1C23_HUMAN "Keratin, type I cytoskeletal 23 (Cytokeratin-23) (CK-23) (Keratin-23) (K23)" KRT23 Homo sapiens (Human) epithelial cell differentiation [GO:0030855]; intermediate filament organization [GO:0045109] cytosol [GO:0005829]; intermediate filament [GO:0005882] structural molecule activity [GO:0005198] 0.92474 -1.0012 EDLIKVLEDMR 0 0 0 0 0 0 0 0 0 0 9.92398 0 0 0 0 0 9.21087 0 0 9.0886 0 0 0 0 0 0 0 Q9C086 IN80B_HUMAN INO80 complex subunit B (High mobility group AT-hook 1-like 4) (IES2 homolog) (hIes2) (PAP-1-associated protein 1) (PAPA-1) (Zinc finger HIT domain-containing protein 4) INO80B HMGA1L4 PAPA1 ZNHIT4 Homo sapiens (Human) chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of telomere maintenance in response to DNA damage [GO:1904507]; regulation of cell cycle [GO:0051726]; regulation of chromosome organization [GO:0033044]; regulation of DNA repair [GO:0006282]; regulation of DNA replication [GO:0006275]; regulation of DNA strand elongation [GO:0060382]; regulation of embryonic development [GO:0045995]; telomere maintenance [GO:0000723] Ino80 complex [GO:0031011]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] metal ion binding [GO:0046872] 0.82124 0.21796 CSVPGCPHPR 0 0 0 0 0 0 16.0694 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9C093 SPEF2_HUMAN Sperm flagellar protein 2 (Protein KPL2) SPEF2 KIAA1770 KPL2 Homo sapiens (Human) brain morphogenesis [GO:0048854]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; respiratory system development [GO:0060541]; skeletal system morphogenesis [GO:0048705]; sperm axoneme assembly [GO:0007288]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; manchette [GO:0002177]; sperm flagellum [GO:0036126]; sperm midpiece [GO:0097225] 0.96958 -3.5228 ALALLEDLVTKVVDVYK 0 0 0 0 10.8409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2682 Q9C098 DCLK3_HUMAN Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like and CAM kinase-like 3) (Doublecortin-like kinase 3) DCLK3 DCAMKL3 DCDC3C KIAA1765 Homo sapiens (Human) peptidyl-serine phosphorylation [GO:0018105] cytoplasm [GO:0005737]; nucleus [GO:0005634] ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96939 -4.1733 APSPRLR 0 15.4896 0 11.6484 0 0 0 0 0 0 9.47326 0 9.00739 11.223 0 0 0 13.5191 0 0 0 9.52812 0 0 0 0 0 Q9C099 LRCC1_HUMAN Leucine-rich repeat and coiled-coil domain-containing protein 1 (Centrosomal leucine-rich repeat and coiled-coil domain-containing protein) LRRCC1 CLERC KIAA1764 Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301] centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737] 0.96922 -4.477 AVILQTLPQLR 10.2287 0 0 0 0 0 0 9.96466 0 0 0 0 0 0 0 12.3233 10.0195 0 8.47752 0 9.65338 0 9.9432 0 0 0 0 Q9C0A0 CNTP4_HUMAN Contactin-associated protein-like 4 (Cell recognition molecule Caspr4) CNTNAP4 CASPR4 KIAA1763 Homo sapiens (Human) "cell adhesion [GO:0007155]; regulation of grooming behavior [GO:2000821]; regulation of synaptic transmission, dopaminergic [GO:0032225]; regulation of synaptic transmission, GABAergic [GO:0032228]" cell projection [GO:0042995]; presynaptic membrane [GO:0042734] 0.95107 -1.4381 LSREMIK 0 0 9.23156 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9C0A1 ZFHX2_HUMAN Zinc finger homeobox protein 2 (Zinc finger homeodomain protein 2) (ZFH-2) ZFHX2 KIAA1056 KIAA1762 ZNF409 Homo sapiens (Human) adult behavior [GO:0030534]; brain development [GO:0007420]; regulation of neuron differentiation [GO:0045664]; regulation of sensory perception of pain [GO:0051930]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; zinc ion binding [GO:0008270]" 0.96948 -4.7267 FLPFEALSRYAAQFRK 0 0 0 0 0 0 0 0 0 11.1619 0 0 9.28716 9.14845 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9C0A6 SETD5_HUMAN Histone-lysine N-methyltransferase SETD5 (EC 2.1.1.359) (EC 2.1.1.367) (SET domain-containing protein 5) SETD5 KIAA1757 Homo sapiens (Human) cognition [GO:0050890]; methylation [GO:0032259]; negative regulation of transcription by RNA polymerase III [GO:0016480]; regulation of chromatin organization [GO:1902275]; regulation of DNA-templated transcription elongation [GO:0032784]; regulation of synapse assembly [GO:0051963] chromatin [GO:0000785]; euchromatin [GO:0000791]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] histone H3K36 methyltransferase activity [GO:0046975]; histone H3K36 trimethyltransferase activity [GO:0140955]; histone H3K9 methyltransferase activity [GO:0046974]; histone H3K9 monomethyltransferase activity [GO:0140948]; histone H3K9me2 methyltransferase activity [GO:0140947]; transcription corepressor activity [GO:0003714] 0.96064 -1.9927 FIRRSCTPNAEVR 0 0 0 0 0 0 0 0 0 0 12.3461 0 0 10.8977 0 0 0 0 0 0 0 0 0 0 0 10.5264 11.0007 Q9C0B0 UNK_HUMAN RING finger protein unkempt homolog (Zinc finger CCCH domain-containing protein 5) UNK KIAA1753 ZC3H5 ZC3HDC5 Homo sapiens (Human) cell morphogenesis involved in neuron differentiation [GO:0048667]; in utero embryonic development [GO:0001701]; negative regulation of cytoplasmic translation [GO:2000766]; neuron migration [GO:0001764] cytoplasm [GO:0005737]; polysome [GO:0005844] metal ion binding [GO:0046872]; mRNA CDS binding [GO:1990715]; polysome binding [GO:1905538]; RNA binding [GO:0003723] 0.9649 -2.3787 CLKCQEQKR 0 0 0 0 12.8228 0 9.0465 0 9.65476 12.6464 12.2397 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3832 0 Q9C0B1 FTO_HUMAN Alpha-ketoglutarate-dependent dioxygenase FTO (Fat mass and obesity-associated protein) (U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO) (EC 1.14.11.-) (U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO) (EC 1.14.11.-) (mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO) (m6A(m)-demethylase FTO) (EC 1.14.11.-) (mRNA N(6)-methyladenosine demethylase FTO) (EC 1.14.11.53) (tRNA N1-methyl adenine demethylase FTO) (EC 1.14.11.-) FTO KIAA1752 Homo sapiens (Human) adipose tissue development [GO:0060612]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; mRNA destabilization [GO:0061157]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; regulation of brown fat cell differentiation [GO:0090335]; regulation of lipid storage [GO:0010883]; regulation of multicellular organism growth [GO:0040014]; regulation of respiratory system process [GO:0044065]; regulation of white fat cell proliferation [GO:0070350]; RNA repair [GO:0042245]; temperature homeostasis [GO:0001659] cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; mRNA N6-methyladenosine dioxygenase activity [GO:1990931]; oxidative DNA demethylase activity [GO:0035516]; oxidative RNA demethylase activity [GO:0035515]; transferase activity [GO:0016740]; tRNA demethylase activity [GO:1990984] 0.79905 0.23965 ILIGNPGCTYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.80126 0 0 0 0 0 0 0 0 0 0 Q9C0B2 CFA74_HUMAN Cilia- and flagella-associated protein 74 CFAP74 C1orf222 KIAA1751 Homo sapiens (Human) axoneme assembly [GO:0035082] axoneme [GO:0005930]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; sperm flagellum [GO:0036126] 0.96973 -4.9868 DKTWNYISDFCK 0 0 10.496 0 0 0 9.84438 0 9.83924 9.43006 11.5741 0 0 0 0 12.9309 11.5379 11.6334 9.47409 0 9.6189 10.4223 9.17388 0 0 0 0 Q9C0B7 TNG6_HUMAN Transport and Golgi organization protein 6 homolog (Transmembrane and coiled-coil domain-containing protein 7) TANGO6 KIAA1746 TMCO7 Homo sapiens (Human) protein secretion [GO:0009306] membrane [GO:0016020] 0.96827 -3.6523 ALGDMVSKYR 0 0 0 0 0 0 0 0 0 0 0 0 0 8.76785 0 0 0 0 0 0 0 10.3039 0 0 0 0 0 Q9C0C2 TB182_HUMAN 182 kDa tankyrase-1-binding protein TNKS1BP1 KIAA1741 TAB182 Homo sapiens (Human) cellular response to ionizing radiation [GO:0071479]; double-strand break repair [GO:0006302]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein autophosphorylation [GO:0031954]; telomere maintenance via telomerase [GO:0007004] adherens junction [GO:0005912]; CCR4-NOT complex [GO:0030014]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; heterochromatin [GO:0000792]; nucleus [GO:0005634]; plasma membrane [GO:0005886] ankyrin repeat binding [GO:0071532]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; protein-containing complex binding [GO:0044877] 0.96361 -2.2356 LTFNHDGSSR 0 0 0 0 0 8.85549 0 0 0 0 0 0 0 0 0 0 0 11.2031 0 0 0 0 0 8.4814 9.88748 0 9.61152 Q9C0C4 SEM4C_HUMAN Semaphorin-4C SEMA4C KIAA1739 SEMAI UNQ5855/PRO34487 Homo sapiens (Human) cell migration in hindbrain [GO:0021535]; cerebellum development [GO:0021549]; muscle cell differentiation [GO:0042692]; negative chemotaxis [GO:0050919]; negative regulation of axon extension involved in axon guidance [GO:0048843]; neural crest cell migration [GO:0001755]; neural tube closure [GO:0001843]; positive regulation of cell migration [GO:0030335]; positive regulation of stress-activated MAPK cascade [GO:0032874]; semaphorin-plexin signaling pathway [GO:0071526] extracellular space [GO:0005615]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; synaptic vesicle membrane [GO:0030672] chemorepellent activity [GO:0045499]; semaphorin receptor binding [GO:0030215] 0.92263 -1.1035 GAKATER 0 0 0 0 0 0 0 0 0 0 0 9.45576 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9C0C6 CIPC_HUMAN CLOCK-interacting pacemaker (CLOCK-interacting circadian protein) CIPC KIAA1737 Homo sapiens (Human) negative regulation of circadian rhythm [GO:0042754]; negative regulation of DNA-templated transcription [GO:0045892]; rhythmic process [GO:0048511] cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.86413 0.086297 TAKNAFPTLSPMVVMK 0 0 0 0 9.31393 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9C0C7 AMRA1_HUMAN Activating molecule in BECN1-regulated autophagy protein 1 (DDB1- and CUL4-associated factor 3) AMBRA1 DCAF3 KIAA1736 Homo sapiens (Human) autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cellular response to starvation [GO:0009267]; mitophagy [GO:0000423]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; neural tube development [GO:0021915]; positive regulation of autophagy [GO:0010508]; positive regulation of free ubiquitin chain polymerization [GO:1904544]; positive regulation of mitophagy [GO:1901526]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of regulatory T cell differentiation [GO:0045591]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of transcription by RNA polymerase II [GO:0006357]; response to mitochondrial depolarisation [GO:0098780] autophagosome [GO:0005776]; axoneme [GO:0005930]; Cul4-RING E3 ubiquitin ligase complex [GO:0080008]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335] GTPase binding [GO:0051020]; molecular function inhibitor activity [GO:0140678]; protein phosphatase binding [GO:0019903]; ubiquitin ligase-substrate adaptor activity [GO:1990756]; ubiquitin protein ligase binding [GO:0031625] 0.96382 -2.4051 HELQCDLRR 0 0 12.7226 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9C0C9 UBE2O_HUMAN (E3-independent) E2 ubiquitin-conjugating enzyme (EC 2.3.2.24) (E2/E3 hybrid ubiquitin-protein ligase UBE2O) (Ubiquitin carrier protein O) (Ubiquitin-conjugating enzyme E2 O) (Ubiquitin-conjugating enzyme E2 of 230 kDa) (Ubiquitin-conjugating enzyme E2-230K) (Ubiquitin-protein ligase O) UBE2O KIAA1734 Homo sapiens (Human) "positive regulation of BMP signaling pathway [GO:0030513]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; retrograde transport, endosome to Golgi [GO:0042147]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; RNA binding [GO:0003723]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.968 -2.8861 CLYVFPAK 0 9.0798 0 0 0 15.4799 0 0 0 0 9.78851 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9C0D0 PHAR1_HUMAN Phosphatase and actin regulator 1 PHACTR1 KIAA1733 RPEL1 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; actomyosin structure organization [GO:0031032]; cell motility [GO:0048870]; cerebral cortex development [GO:0021987]; dendrite arborization [GO:0140059]; regulation of neuron migration [GO:2001222]; stress fiber assembly [GO:0043149] cytosol [GO:0005829]; nucleus [GO:0005634]; synapse [GO:0045202] actin binding [GO:0003779]; protein phosphatase inhibitor activity [GO:0004864] 0.83496 0.19209 TLAMTMQR 0 0 0 0 0 0 0 0 0 0 9.45822 0 0 0 0 0 0 0 8.95417 0 0 0 0 0 0 0 0 Q9C0D2 CE295_HUMAN Centrosomal protein of 295 kDa CEP295 KIAA1731 Homo sapiens (Human) centriole replication [GO:0007099]; positive regulation of centriole elongation [GO:1903724]; positive regulation of centrosome duplication [GO:0010825]; positive regulation of establishment of protein localization [GO:1904951]; positive regulation of protein acetylation [GO:1901985]; regulation of centriole replication [GO:0046599] centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; mitotic spindle microtubule [GO:1990498]; plasma membrane [GO:0005886] microtubule binding [GO:0008017] 0.97005 -3.2977 ALQEQLATQR 9.71961 0 10.1313 0 0 0 14.6853 0 0 0 10.3503 0 0 0 0 0 0 0 0 0 0 9.10436 10.0304 0 11.7473 0 0 Q9C0D3 ZY11B_HUMAN Protein zyg-11 homolog B ZYG11B KIAA1730 Homo sapiens (Human) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515] Cul2-RING ubiquitin ligase complex [GO:0031462] 0.72578 0.34761 HLNHLDISDDK 0 0 0 8.52697 0 0 0 8.38081 8.45992 10.4426 9.11361 0 10.55 10.6701 10.7019 11.0398 10.8847 0 10.4113 10.3373 10.3074 9.93712 9.9486 9.99986 0 0 10.9388 Q9C0D4 Z518B_HUMAN Zinc finger protein 518B ZNF518B KIAA1729 Homo sapiens (Human) chromatin organization [GO:0006325]; regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.55425 0.55729 LTYQNAEEASQIK 0 0 0 0 0 0 9.52203 0 0 0 0 0 0 10.1447 0 0 0 0 0 9.98584 0 0 0 0 0 0 0 Q9C0D5 TANC1_HUMAN "Protein TANC1 (Tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 1)" TANC1 KIAA1728 Homo sapiens (Human) dendritic spine maintenance [GO:0097062]; myoblast fusion [GO:0007520]; regulation of postsynapse organization [GO:0099175]; visual learning [GO:0008542] axon terminus [GO:0043679]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; postsynaptic density [GO:0014069] 0.96966 -4.7537 LLLERGCDVNLSDK 0 0 0 0 0 10.303 0 0 0 0 0 0 0 0 0 0 11.178 9.87977 0 0 0 0 0 0 9.89803 0 8.68236 Q9C0D6 FHDC1_HUMAN FH2 domain-containing protein 1 (Inverted formin-1) FHDC1 INF1 KIAA1727 Homo sapiens (Human) actin filament polymerization [GO:0030041]; cilium assembly [GO:0060271]; Golgi ribbon formation [GO:0090161]; stress fiber assembly [GO:0043149] actin filament [GO:0005884]; cilium [GO:0005929]; cytoplasmic microtubule [GO:0005881]; Golgi apparatus [GO:0005794]; microtubule [GO:0005874] actin binding [GO:0003779]; microtubule binding [GO:0008017] 0.92742 -1.2009 LPRGSSGSSSTRPGR 0 0 0 0 0 0 9.47318 9.61956 0 10.2803 11.6909 0 0 0 0 0 0 0 10.5016 0 0 0 0 0 0 0 0 Q9C0D7 ZC12C_HUMAN Probable ribonuclease ZC3H12C (EC 3.1.-.-) (MCP-induced protein 3) (Zinc finger CCCH domain-containing protein 12C) ZC3H12C KIAA1726 MCPIP3 Homo sapiens (Human) "RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]" cytoplasmic ribonucleoprotein granule [GO:0036464]; nucleus [GO:0005634] metal ion binding [GO:0046872]; mRNA binding [GO:0003729]; RNA endonuclease activity [GO:0004521] 0.96932 -3.0338 DLANEKPEWKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.08828 0 0 0 0 0 0 10.9885 10.799 0 0 0 Q9C0E4 GRIP2_HUMAN Glutamate receptor-interacting protein 2 (GRIP-2) GRIP2 KIAA1719 Homo sapiens (Human) "artery smooth muscle contraction [GO:0014824]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; Notch signaling pathway [GO:0007219]; positive regulation of blood pressure [GO:0045777]; vesicle-mediated transport in synapse [GO:0099003]" "cytosol [GO:0005829]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; neuron spine [GO:0044309]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic membrane [GO:0045211]" glutamate receptor binding [GO:0035254] 0.92411 -1.049 DPMRHDFGFSVSDGLLEK 9.64422 0 9.59373 0 0 0 0 0 0 10.4287 10.1807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9C0E8 LNP_HUMAN Endoplasmic reticulum junction formation protein lunapark (ER junction formation factor lunapark) LNPK KIAA1715 LNP Homo sapiens (Human) blood coagulation [GO:0007596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum tubular network maintenance [GO:0071788]; endoplasmic reticulum tubular network organization [GO:0071786]; limb development [GO:0060173]; positive regulation of endoplasmic reticulum tubular network organization [GO:1903373]; regulation of chondrocyte differentiation [GO:0032330] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum tubular network [GO:0071782]; endoplasmic reticulum tubular network membrane [GO:0098826]; membrane [GO:0016020]; nucleoplasm [GO:0005654] identical protein binding [GO:0042802]; metal ion binding [GO:0046872] 0.87714 -0.011519 ILEEVMEKETYK 0 0 0 0 0 0 0 0 0 0 0 11.5459 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.71122 Q9C0F0 ASXL3_HUMAN Putative Polycomb group protein ASXL3 (Additional sex combs-like protein 3) ASXL3 KIAA1713 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; negative regulation of lipid biosynthetic process [GO:0051055]; positive regulation of transcription by RNA polymerase II [GO:0045944] PR-DUB complex [GO:0035517] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; peroxisome proliferator activated receptor binding [GO:0042975] 0.92948 -1.2311 DSSLTNTAVQSK 14.7137 14.7573 0 10.7521 14.206 9.98071 10.0243 14.7377 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9C0F1 CEP44_HUMAN Centrosomal protein of 44 kDa (Cep44) (HBV PreS1-transactivated protein 3) (PS1TP3) CEP44 KIAA1712 Homo sapiens (Human) centriole replication [GO:0007099]; centriole-centriole cohesion [GO:0010457]; centrosome cycle [GO:0007098] centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; midbody [GO:0030496]; spindle pole [GO:0000922] microtubule binding [GO:0008017] 0.8281 0.20478 DQFNYKPILTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.637 0 0 0 0 0 0 0 0 0 0 Q9C0G0 ZN407_HUMAN Zinc finger protein 407 ZNF407 KIAA1703 Homo sapiens (Human) regulation of gene expression [GO:0010468] nucleus [GO:0005634] DNA binding [GO:0003677]; zinc ion binding [GO:0008270] 0.89855 -0.59862 CHVCGVAFVMK 0 8.82899 0 0 0 8.6347 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9C0G6 DYH6_HUMAN Dynein axonemal heavy chain 6 (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6) DNAH6 DNAHC6 DNHL1 HL2 KIAA1697 Homo sapiens (Human) microtubule-based movement [GO:0007018] axoneme [GO:0005930]; dynein complex [GO:0030286]; microtubule [GO:0005874] ATP binding [GO:0005524]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; minus-end-directed microtubule motor activity [GO:0008569] 0.92451 -1.0021 DLAKALAIQCVVFNCSDGLDYK 0 0 12.2975 0 0 0 0 0 9.08404 0 12.9814 12.7517 10.0658 0 9.85381 0 0 10.6468 0 9.21805 0 0 0 0 0 8.29811 0 Q9C0H5 RHG39_HUMAN Rho GTPase-activating protein 39 ARHGAP39 KIAA1688 Homo sapiens (Human) postsynapse organization [GO:0099173]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; nucleus [GO:0005634] GTPase activator activity [GO:0005096] 0.96954 -3.1774 AALTGAK 0 9.72514 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0599 0 0 0 0 0 0 0 10.5974 0 0 Q9C0H9 SRCN1_HUMAN SRC kinase signaling inhibitor 1 (SNAP-25-interacting protein) (SNIP) (p130Cas-associated protein) (p140Cap) SRCIN1 KIAA1684 P140 SNIP Homo sapiens (Human) exocytosis [GO:0006887]; negative regulation of protein secretion [GO:0050709]; negative regulation of protein tyrosine kinase activity [GO:0061099]; positive regulation of protein tyrosine kinase activity [GO:0061098]; postsynaptic actin cytoskeleton organization [GO:0098974]; regulation of cell migration [GO:0030334]; regulation of dendritic spine morphogenesis [GO:0061001]; substrate adhesion-dependent cell spreading [GO:0034446] actin cytoskeleton [GO:0015629]; axon [GO:0030424]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; filopodium [GO:0030175]; glutamatergic synapse [GO:0098978]; lamellipodium [GO:0030027]; neuronal cell body [GO:0043025]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; synapse [GO:0045202] protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901] 0.96943 -3.5919 AAQGQAGSPDKSKHGK 0 0 0 0 0 0 0 0 0 9.66276 0 0 0 0 0 0 0 10.025 0 9.40035 0 0 0 0 0 0 0 Q9C0I1 MTMRC_HUMAN Myotubularin-related protein 12 (Inactive phosphatidylinositol 3-phosphatase 12) (Phosphatidylinositol 3 phosphate 3-phosphatase adapter subunit) (3-PAP) (3-phosphatase adapter protein) MTMR12 KIAA1682 PIP3AP Homo sapiens (Human) toxin transport [GO:1901998] cytoplasm [GO:0005737]; cytosol [GO:0005829]; sarcomere [GO:0030017]; sarcoplasmic reticulum [GO:0016529] 0.8822 -0.30076 VFQFCLRYTK 0 0 0 0 0 0 0 0 0 0 0 10.212 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9C0I3 CCSE1_HUMAN Serine-rich coiled-coil domain-containing protein 1 (Coiled-coil serine-rich protein 1) CCSER1 FAM190A KIAA1680 Homo sapiens (Human) 0.91786 -0.85625 AGSSSSK 0 0 0 0 0 0 0 0 0 10.5285 0 0 10.6746 11.7319 0 0 0 0 0 0 0 9.96867 0 0 0 0 0 Q9C0I4 THS7B_HUMAN Thrombospondin type-1 domain-containing protein 7B THSD7B KIAA1679 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532] plasma membrane [GO:0005886] 0.9695 -3.1519 MFPKSNLTVTCWVWR 0 0 0 0 0 10.3144 0 0 0 0 0 0 0 0 0 0 0 0 9.69246 11.1069 0 0 0 0 0 0 0 Q9C0I9 LRC27_HUMAN Leucine-rich repeat-containing protein 27 LRRC27 KIAA1674 Homo sapiens (Human) cardiac muscle cell development [GO:0055013] cytoskeleton [GO:0005856]; sarcomere [GO:0030017] actin binding [GO:0003779] 0.91464 -0.78218 EMSALQERNLEEK 0 0 12.3028 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9C0J1 B3GN4_HUMAN "N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4 (EC 2.4.1.149) (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4) (BGnT-4) (Beta-1,3-Gn-T4) (Beta-1,3-N-acetylglucosaminyltransferase 4) (Beta3Gn-T4)" B3GNT4 UNQ1898/PRO4344 Homo sapiens (Human) keratan sulfate biosynthetic process [GO:0018146]; O-glycan processing [GO:0016266]; poly-N-acetyllactosamine biosynthetic process [GO:0030311]; protein O-linked glycosylation [GO:0006493] Golgi membrane [GO:0000139]; membrane [GO:0016020] "beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity [GO:0008457]; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity [GO:0008532]; UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity [GO:0008499]" 0.87983 -0.027874 GPAMLCR 8.89051 0 0 0 0 0 9.70494 0 10.3399 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9C0J8 WDR33_HUMAN pre-mRNA 3' end processing protein WDR33 (WD repeat-containing protein 33) (WD repeat-containing protein of 146 kDa) WDR33 WDC146 Homo sapiens (Human) mRNA polyadenylation [GO:0006378]; postreplication repair [GO:0006301]; spermatogenesis [GO:0007283] collagen trimer [GO:0005581]; fibrillar center [GO:0001650]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] RNA binding [GO:0003723] 0.95451 -1.5105 MFQAHKEAIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.7612 0 0 0 0 Q9GZK3 OR2B2_HUMAN Olfactory receptor 2B2 (Hs6M1-10) (Olfactory receptor 2B9) (Olfactory receptor 6-1) (OR6-1) OR2B2 OR2B9 Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of smell [GO:0050911] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.93151 -1.2707 SLLNQEIR 0 0 9.1604 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3397 0 0 0 0 0 0 Q9GZK7 O11A1_HUMAN Olfactory receptor 11A1 (Hs6M1-18) (Olfactory receptor 11A2) (Olfactory receptor OR6-30) OR11A1 OR11A2 Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.96166 -2.5603 VPAGASR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.88313 0 0 0 0 0 0 0 0 0 0 Q9GZL7 WDR12_HUMAN Ribosome biogenesis protein WDR12 (WD repeat-containing protein 12) WDR12 Homo sapiens (Human) "maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; Notch signaling pathway [GO:0007219]; regulation of cell cycle [GO:0051726]; ribosomal large subunit biogenesis [GO:0042273]" "nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; PeBoW complex [GO:0070545]; preribosome, large subunit precursor [GO:0030687]" ribonucleoprotein complex binding [GO:0043021] 0.88482 -0.28638 FCSGSWDKMLK 0 0 11.5139 0 0 0 0 0 0 0 0 9.44288 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9GZM5 YIPF3_HUMAN "Protein YIPF3 (Killer lineage protein 1) (Natural killer cell-specific antigen KLIP1) (YIP1 family member 3) [Cleaved into: Protein YIPF3, 36 kDa form III]" YIPF3 C6orf109 KLIP1 Homo sapiens (Human) cell differentiation [GO:0030154] Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133] 0.9515 -1.3978 GFKGQLSRQVADQMWQAGK 0 0 0 0 9.09527 0 0 0 0 0 0 0 9.90573 0 0 0 0 0 0 0 0 0 0 0 9.89532 10.0584 0 Q9GZM7 TINAL_HUMAN Tubulointerstitial nephritis antigen-like (Glucocorticoid-inducible protein 5) (Oxidized LDL-responsive gene 2 protein) (OLRG-2) (Tubulointerstitial nephritis antigen-related protein) (TIN Ag-related protein) (TIN-Ag-RP) TINAGL1 GIS5 LCN7 OLRG2 TINAGL PP6614 PSEC0088 UNQ204/PRO230 Homo sapiens (Human) endosomal transport [GO:0016197] collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615] extracellular matrix structural constituent [GO:0005201]; laminin binding [GO:0043236] 0.88278 0.010461 IYPVLGTYWDNCNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.41124 0 0 0 0 0 0 0 0 0 0 0 0 Q9GZM8 NDEL1_HUMAN Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin-associated protein 1) NDEL1 EOPA MITAP1 NUDEL Homo sapiens (Human) activation of GTPase activity [GO:0090630]; cell migration [GO:0016477]; central nervous system neuron axonogenesis [GO:0021955]; centrosome localization [GO:0051642]; cerebral cortex radially oriented cell migration [GO:0021799]; chromosome segregation [GO:0007059]; establishment of chromosome localization [GO:0051303]; establishment of mitotic spindle orientation [GO:0000132]; inner cell mass cell proliferation [GO:0001833]; insulin receptor signaling pathway [GO:0008286]; lysosome localization [GO:0032418]; microtubule nucleation [GO:0007020]; mitotic centrosome separation [GO:0007100]; neurofilament cytoskeleton organization [GO:0060052]; neuron projection extension [GO:1990138]; positive regulation of GTPase activity [GO:0043547]; positive regulation of ruffle assembly [GO:1900029]; radial glia-guided pyramidal neuron migration [GO:0140650]; regulation of intracellular protein transport [GO:0033157]; regulation of neuron projection development [GO:0010975]; retrograde axonal transport [GO:0008090]; vesicle transport along microtubule [GO:0047496] axon cytoplasm [GO:1904115]; axon hillock [GO:0043203]; cell leading edge [GO:0031252]; centrosome [GO:0005813]; cytosol [GO:0005829]; kinesin complex [GO:0005871]; kinetochore [GO:0000776]; microtubule [GO:0005874]; neurofilament cytoskeleton [GO:0060053]; spindle [GO:0005819]; synaptic vesicle [GO:0008021] alpha-tubulin binding [GO:0043014]; beta-tubulin binding [GO:0048487]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017] 0.96584 -2.7195 AIKEQLHK 0 0 0 9.8955 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9GZN7 ROGDI_HUMAN Protein rogdi homolog ROGDI Homo sapiens (Human) brain development [GO:0007420]; hemopoiesis [GO:0030097]; neurogenesis [GO:0022008]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell population proliferation [GO:0008284] axon [GO:0030424]; dendrite [GO:0030425]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; nuclear envelope [GO:0005635]; perikaryon [GO:0043204]; RAVE complex [GO:0043291]; synaptic vesicle [GO:0008021] 0.79446 0.24503 FTLPGSGTEGPAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3245 0 0 0 0 10.0768 0 0 0 Q9GZP1 NRSN2_HUMAN Neurensin-2 NRSN2 C20orf98 Homo sapiens (Human) nervous system development [GO:0007399] neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133] 0.91212 -0.75229 MPSCNRSCSCSR 0 0 0 0 0 0 0 0 0 0 10.1254 10.157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9GZP4 PITH1_HUMAN PITH domain-containing protein 1 PITHD1 C1orf128 AD039 HT014 PP603 Homo sapiens (Human) penetration of cumulus oophorus [GO:0061956]; penetration of zona pellucida [GO:0007341]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of megakaryocyte differentiation [GO:0045654]; regulation of proteasomal protein catabolic process [GO:0061136]; spermatid development [GO:0007286] cytoplasm [GO:0005737]; nucleus [GO:0005634]; sperm cytoplasmic droplet [GO:0097598] 0.91373 -0.75727 DLTGELEYATK 11.0184 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3921 9.95102 0 0 0 0 0 0 0 0 0 0 0 Q9GZP7 VN1R1_HUMAN Vomeronasal type-1 receptor 1 (G-protein coupled receptor GPCR24) (hGPCR24) (V1r-like receptor 1) (V3r-related gene protein) (Vomeronasal olfactory receptor chromosome 19 subtype I member 1) VN1R1 V1RL1 VNR19I1 Homo sapiens (Human) response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606] plasma membrane [GO:0005886] pheromone receptor activity [GO:0016503] 0.8821 -0.019128 LNPSICRWMEIK 0 0 0 0 10.6852 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.22337 0 0 0 0 0 Q9GZQ4 NMUR2_HUMAN Neuromedin-U receptor 2 (NMU-R2) (G-protein coupled receptor FM-4) (G-protein coupled receptor TGR-1) NMUR2 NMU2R TGR1 Homo sapiens (Human) arachidonic acid secretion [GO:0050482]; calcium ion transport [GO:0006816]; calcium-mediated signaling [GO:0019722]; cell-cell signaling [GO:0007267]; central nervous system development [GO:0007417]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; grooming behavior [GO:0007625]; inositol phosphate-mediated signaling [GO:0048016]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; reduction of food intake in response to dietary excess [GO:0002023]; regulation of sensory perception of pain [GO:0051930]; regulation of smooth muscle contraction [GO:0006940]; response to pain [GO:0048265] membrane [GO:0016020]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; GTP binding [GO:0005525]; intracellular calcium activated chloride channel activity [GO:0005229]; neuromedin U binding [GO:0042924]; neuromedin U receptor activity [GO:0001607] 0.8761 0.022405 FQAAFQNVISSFHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5866 0 Q9GZR1 SENP6_HUMAN Sentrin-specific protease 6 (EC 3.4.22.-) (SUMO-1-specific protease 1) (Sentrin/SUMO-specific protease SENP6) SENP6 KIAA0797 SSP1 SUSP1 FKSG6 Homo sapiens (Human) protein desumoylation [GO:0016926]; protein modification by small protein removal [GO:0070646]; protein sumoylation [GO:0016925]; regulation of kinetochore assembly [GO:0090234]; regulation of spindle assembly [GO:0090169] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] SUMO-specific endopeptidase activity [GO:0070139] 0.96954 -4.0881 DQFGNSIINTPLKR 0 0 0 0 0 0 11.2664 0 10.037 9.39658 0 0 0 0 0 0 0 0 0 0 9.91244 0 0 0 9.64024 10.1298 9.83482 Q9GZR2 REXO4_HUMAN RNA exonuclease 4 (EC 3.1.-.-) (Exonuclease XPMC2) (Prevents mitotic catastrophe 2 protein homolog) (hPMC2) REXO4 PMC2 XPMC2H Homo sapiens (Human) DNA catabolic process [GO:0006308]; DNA repair [GO:0006281]; regulation of DNA-templated transcription [GO:0006355]; rRNA processing [GO:0006364] nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 3'-5' exonuclease activity [GO:0008408]; double-stranded DNA binding [GO:0003690]; endonuclease activity [GO:0004519]; exonuclease activity [GO:0004527]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697] 0.93387 -1.2888 EWESMAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.10899 0 0 0 0 0 0 0 0 0 0 0 0 Q9GZR5 ELOV4_HUMAN Elongation of very long chain fatty acids protein 4 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL4) (ELOVL fatty acid elongase 4) (ELOVL FA elongase 4) (Very long chain 3-ketoacyl-CoA synthase 4) (Very long chain 3-oxoacyl-CoA synthase 4) ELOVL4 Homo sapiens (Human) "fatty acid biosynthetic process [GO:0006633]; fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; fatty acid elongation, saturated fatty acid [GO:0019367]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; sphingolipid biosynthetic process [GO:0030148]; unsaturated fatty acid biosynthetic process [GO:0006636]; very long-chain fatty acid biosynthetic process [GO:0042761]" endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789] 3-oxo-cerotoyl-CoA synthase activity [GO:0102337]; fatty acid elongase activity [GO:0009922]; G protein-coupled photoreceptor activity [GO:0008020]; very-long-chain 3-ketoacyl-CoA synthase activity [GO:0102756] 0.87033 0.063709 TAMNGISANGVSK 0 0 0 0 0 0 0 0 0 0 9.26744 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9GZR7 DDX24_HUMAN ATP-dependent RNA helicase DDX24 (EC 3.6.4.13) (DEAD box protein 24) DDX24 Homo sapiens (Human) RNA metabolic process [GO:0016070] membrane [GO:0016020]; nucleolus [GO:0005730] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.92514 -1.1776 EQTGNLKQELDDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.80958 0 Q9GZS0 DNAI2_HUMAN Dynein axonemal intermediate chain 2 (Axonemal dynein intermediate chain 2) DNAI2 Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; outer dynein arm assembly [GO:0036158] axonemal dynein complex [GO:0005858]; axoneme [GO:0005930]; dynein axonemal particle [GO:0120293]; external side of plasma membrane [GO:0009897]; microtubule [GO:0005874]; outer dynein arm [GO:0036157]; sperm flagellum [GO:0036126] dynein heavy chain binding [GO:0045504]; dynein light chain binding [GO:0045503]; microtubule motor activity [GO:0003777] 0.40611 0.69766 EIVYVYVK 9.62115 0 0 9.77512 0 0 8.99577 0 0 11.8389 11.2576 11.1467 0 9.4483 9.43673 0 0 0 0 9.02209 8.8453 0 0 0 0 0 0 Q9GZS3 SKI8_HUMAN "Superkiller complex protein 8 (Ski8) (Meiotic recombination REC14 protein homolog) (WD repeat-containing protein 61) [Cleaved into: Superkiller complex protein 8, N-terminally processed (WD repeat-containing protein 61, N-terminally processed)]" SKIC8 WDR61 Homo sapiens (Human) "histone H3-K4 methylation [GO:0051568]; negative regulation of myeloid cell differentiation [GO:0045638]; nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay [GO:0070478]; rescue of stalled ribosome [GO:0072344]; transcription elongation by RNA polymerase II [GO:0006368]; Wnt signaling pathway [GO:0016055]" Cdc73/Paf1 complex [GO:0016593]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Ski complex [GO:0055087] 0.87945 0.0053906 VNIFGVESGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15.3463 0 0 0 0 0 0 Q9GZS9 CHST5_HUMAN Carbohydrate sulfotransferase 5 (EC 2.8.2.-) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-alpha) (GST4-alpha) (Intestinal N-acetylglucosamine-6-O-sulfotransferase) (I-GlcNAc6ST) (Intestinal GlcNAc-6-sulfotransferase) (hIGn6ST) (N-acetylglucosamine 6-O-sulfotransferase 3) (GlcNAc6ST-3) (Gn6st-3) CHST5 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; keratan sulfate biosynthetic process [GO:0018146]; N-acetylglucosamine metabolic process [GO:0006044]; protein sulfation [GO:0006477]; sulfur compound metabolic process [GO:0006790] Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020] N-acetylglucosamine 6-O-sulfotransferase activity [GO:0001517]; sulfotransferase activity [GO:0008146] 0.87085 0.05926 NLSAFFNWATSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1392 0 0 Q9GZT5 WN10A_HUMAN Protein Wnt-10a WNT10A Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; cellular response to transforming growth factor beta stimulus [GO:0071560]; epidermis morphogenesis [GO:0048730]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; neural crest cell differentiation [GO:0014033]; neuron differentiation [GO:0030182]; odontogenesis [GO:0042476]; positive regulation of gene expression [GO:0010628]; regulation of odontogenesis of dentin-containing tooth [GO:0042487]; sebaceous gland development [GO:0048733]; skin development [GO:0043588]; tongue development [GO:0043586] extracellular region [GO:0005576]; extracellular space [GO:0005615] cytokine activity [GO:0005125]; frizzled binding [GO:0005109]; receptor ligand activity [GO:0048018] 0.92449 -1.0418 ASPADLVYFEK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.93281 10.0125 0 0 0 10.4428 0 0 0 9.64604 0 0 0 0 Q9GZT8 NIF3L_HUMAN NIF3-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein) NIF3L1 ALS2CR1 MDS015 My018 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; positive regulation of DNA-templated transcription [GO:0045893] cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nucleus [GO:0005634] identical protein binding [GO:0042802]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629] 0.92593 -1.2118 ITWNTWK 0 10.3891 0 0 0 0 0 0 0 8.45039 0 0 0 0 0 9.13355 0 10.2153 0 0 0 9.86412 0 0 0 0 0 Q9GZU1 MCLN1_HUMAN Mucolipin-1 (ML1) (MG-2) (Mucolipidin) (Transient receptor potential channel mucolipin 1) (TRPML1) MCOLN1 ML4 TRPML1 MSTP080 Homo sapiens (Human) adaptive immune response [GO:0002250]; autophagosome maturation [GO:0097352]; calcium ion export [GO:1901660]; calcium ion transmembrane transport [GO:0070588]; cellular response to calcium ion [GO:0071277]; cellular response to pH [GO:0071467]; monoatomic cation transport [GO:0006812]; phagosome maturation [GO:0090382]; positive regulation of lysosome organization [GO:1905673]; protein homotetramerization [GO:0051289]; transferrin transport [GO:0033572] cell projection [GO:0042995]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; phagocytic cup [GO:0001891]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] "calcium channel activity [GO:0005262]; identical protein binding [GO:0042802]; intracellular phosphatidylinositol-3,5-bisphosphate-sensitive monatomic cation channel activity [GO:0097682]; iron ion transmembrane transporter activity [GO:0005381]; ligand-gated calcium channel activity [GO:0099604]; lipid binding [GO:0008289]; monoatomic cation channel activity [GO:0005261]; NAADP-sensitive calcium-release channel activity [GO:0072345]" 0.96178 -2.039 LKYFFMSPCDK 0 0 0 0 0 0 0 0 0 0 0 9.30191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9GZU5 NYX_HUMAN Nyctalopin NYX CLRP Homo sapiens (Human) response to stimulus [GO:0050896]; visual perception [GO:0007601] extracellular matrix [GO:0031012]; extracellular space [GO:0005615] 0.96123 -2.5603 GVGGAGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.5429 0 0 0 0 9.38003 0 0 0 Q9GZV1 ANKR2_HUMAN Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp) ANKRD2 ARPP Homo sapiens (Human) muscle contraction [GO:0006936]; muscle organ development [GO:0007517]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619] cytosol [GO:0005829]; euchromatin [GO:0000791]; I band [GO:0031674]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; PML body [GO:0016605] protein kinase B binding [GO:0043422]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; structural constituent of muscle [GO:0008307] 0.84754 0.16966 ASLEGHMEILEK 0 0 0 0 0 0 0 0 0 10.3363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9GZV8 PRD14_HUMAN PR domain zinc finger protein 14 (EC 2.1.1.-) (PR domain-containing protein 14) PRDM14 Homo sapiens (Human) cell fate specification [GO:0001708]; cell morphogenesis [GO:0000902]; embryo implantation [GO:0007566]; fertilization [GO:0009566]; fibroblast growth factor receptor signaling pathway [GO:0008543]; germ cell development [GO:0007281]; germ-line stem cell population maintenance [GO:0030718]; histone H3-R26 methylation [GO:0034972]; homeostasis of number of cells within a tissue [GO:0048873]; inactivation of paternal X chromosome [GO:0060817]; inner cell mass cell fate commitment [GO:0001827]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of flagellated sperm motility [GO:1902093]; positive regulation of stem cell population maintenance [GO:1902459]; regulation of DNA methylation [GO:0044030]; regulation of transcription by RNA polymerase II [GO:0006357] nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin DNA binding [GO:0031490]; metal ion binding [GO:0046872]; methyltransferase activity [GO:0008168]; RNA binding [GO:0003723]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977] 0.91637 -0.84983 DKHLKYTPCVDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0751 0 0 0 0 0 0 0 0 0 0 Q9GZX3 CHST6_HUMAN Carbohydrate sulfotransferase 6 (Corneal N-acetylglucosamine-6-O-sulfotransferase) (C-GlcNAc6ST) (hCGn6ST) (EC 2.8.2.21) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-beta) (GST4-beta) (N-acetylglucosamine 6-O-sulfotransferase 5) (GlcNAc6ST-5) (Gn6st-5) CHST6 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; keratan sulfate biosynthetic process [GO:0018146]; N-acetylglucosamine metabolic process [GO:0006044]; sulfur compound metabolic process [GO:0006790] Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139] keratan sulfotransferase activity [GO:0045130]; N-acetylglucosamine 6-O-sulfotransferase activity [GO:0001517] 0.95918 -1.7161 EAFKTSSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.14708 0 0 0 0 0 0 0 0 0 Q9GZX5 ZN350_HUMAN Zinc finger protein 350 (KRAB zinc finger protein ZFQR) (Zinc finger and BRCA1-interacting protein with a KRAB domain 1) (Zinc finger protein ZBRK1) ZNF350 ZBRK1 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] nuclear body [GO:0016604]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription repressor complex [GO:0017053] "DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding [GO:0001162]" 0.55755 0.55213 LQSESLVNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5971 0 0 12.8442 10.2666 0 0 12.9767 0 0 0 Q9GZY4 COA1_HUMAN Cytochrome c oxidase assembly factor 1 homolog (Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 15 kDa) COA1 C7orf44 MITRAC15 Homo sapiens (Human) mitochondrial cytochrome c oxidase assembly [GO:0033617]; mitochondrial respiratory chain complex I assembly [GO:0032981] cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] 0.93355 -1.2829 YAGSRRSMPLGAR 0 0 0 0 0 0 0 0 0 0 0 0 9.41185 9.80986 0 9.8475 0 0 0 0 0 0 0 0 0 0 0 Q9GZY8 MFF_HUMAN Mitochondrial fission factor MFF C2orf33 AD030 AD033 GL004 Homo sapiens (Human) mitochondrial fission [GO:0000266]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrial fusion [GO:0008053]; mitochondrion morphogenesis [GO:0070584]; peroxisome fission [GO:0016559]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; protein targeting to mitochondrion [GO:0006626]; regulation of mitochondrion organization [GO:0010821]; regulation of peroxisome organization [GO:1900063]; release of cytochrome c from mitochondria [GO:0001836] mitochondrial membrane [GO:0031966]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; synaptic vesicle [GO:0008021] identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803] 0.56145 0.51594 AYQQILDVLDENR 0 0 0 0 0 0 0 10.2662 0 0 0 12.5644 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9GZZ7 GFRA4_HUMAN GDNF family receptor alpha-4 (GDNF receptor alpha-4) (GDNFR-alpha-4) (GFR-alpha-4) (Persephin receptor) GFRA4 Homo sapiens (Human) negative regulation of ossification [GO:0030279]; nervous system development [GO:0007399]; ossification [GO:0001503] external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] glial cell-derived neurotrophic factor receptor activity [GO:0016167] 0.92362 -1.0168 AAAGPWRGWGR 0 0 0 8.58007 8.78241 8.65105 8.79152 8.90644 0 0 9.85894 0 0 9.33684 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H040 SPRTN_HUMAN DNA-dependent metalloprotease SPRTN (EC 3.4.24.-) (DNA damage protein targeting VCP) (DVC1) (Protein with SprT-like domain at the N terminus) (Spartan) SPRTN C1orf124 DVC1 UNQ1880/PRO4323 Homo sapiens (Human) DNA damage response [GO:0006974]; positive regulation of protein ubiquitination [GO:0031398]; protein autoprocessing [GO:0016540]; protein-DNA covalent cross-linking repair [GO:0106300]; proteolysis [GO:0006508]; response to UV [GO:0009411]; translesion synthesis [GO:0019985] chromatin [GO:0000785]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] double-stranded DNA binding [GO:0003690]; K63-linked polyubiquitin modification-dependent protein binding [GO:0070530]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; polyubiquitin modification-dependent protein binding [GO:0031593]; single-stranded DNA binding [GO:0003697]; ubiquitin binding [GO:0043130] 0.8992 -0.6131 ISLRNSSK 0 0 10.8532 0 0 0 0 0 0 11.3406 0 0 10.7283 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H061 T126A_HUMAN Transmembrane protein 126A TMEM126A Homo sapiens (Human) mitochondrial respiratory chain complex I assembly [GO:0032981]; optic nerve development [GO:0021554]; toll-like receptor 4 signaling pathway [GO:0034142] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886] 0.7645 0.28501 ENITIVDISR 0 0 0 0 9.76852 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H069 DRC3_HUMAN Dynein regulatory complex subunit 3 (Leucine-rich repeat-containing protein 48) DRC3 LRRC48 Homo sapiens (Human) axoneme [GO:0005930]; cilium [GO:0005929]; cytoplasm [GO:0005737]; sperm flagellum [GO:0036126] 0.88647 -0.3564 EAIQENQEQGKRK 12.5606 0 0 0 0 0 10.128 0 0 0 0 0 8.94125 0 0 8.70719 0 0 0 0 0 0 0 0 0 0 0 Q9H078 CLPB_HUMAN "Mitochondrial disaggregase (EC 3.6.1.-) (Suppressor of potassium transport defect 3) [Cleaved into: Mitochondrial disaggregase, cleaved form]" CLPB SKD3 Homo sapiens (Human) antiviral innate immune response [GO:0140374]; cellular response to heat [GO:0034605]; granulocyte differentiation [GO:0030851]; RIG-I signaling pathway [GO:0039529] cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent protein disaggregase activity [GO:0140545] 0.96361 -2.2363 EVADVLVDGYNVHYGAR 0 0 0 9.13538 8.8464 0 0 0 0 0 0 10.8598 0 0 0 0 0 0 0 0 10.3497 10.9905 0 0 0 0 10.5424 Q9H082 RB33B_HUMAN Ras-related protein Rab-33B RAB33B Homo sapiens (Human) "autophagosome assembly [GO:0000045]; intra-Golgi vesicle-mediated transport [GO:0006891]; negative regulation of constitutive secretory pathway [GO:1903434]; protein localization to Golgi apparatus [GO:0034067]; protein transport [GO:0015031]; Rab protein signal transduction [GO:0032482]; regulation of exocytosis [GO:0017157]; regulation of Golgi organization [GO:1903358]; regulation of retrograde vesicle-mediated transport, Golgi to ER [GO:2000156]; skeletal system morphogenesis [GO:0048705]" endosome [GO:0005768]; Golgi apparatus [GO:0005794]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; presynapse [GO:0098793] GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.88423 -0.10852 IQLWDTAGQERFRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.85158 Q9H089 LSG1_HUMAN Large subunit GTPase 1 homolog (hLsg1) (EC 3.6.1.-) LSG1 Homo sapiens (Human) nuclear export [GO:0051168]; protein transport [GO:0015031]; ribosomal subunit export from nucleus [GO:0000054] Cajal body [GO:0015030]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; membrane [GO:0016020]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654] GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.95471 -1.5705 LLENKMNSDEIK 0 0 0 0 0 0 0 0 0 0 0 0 10.1596 0 0 0 0 0 0 0 9.96441 0 0 0 0 10.3808 0 Q9H091 ZMY15_HUMAN Zinc finger MYND domain-containing protein 15 ZMYND15 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; spermatid development [GO:0007286] cytoplasm [GO:0005737]; male germ cell nucleus [GO:0001673] histone deacetylase binding [GO:0042826]; metal ion binding [GO:0046872] 0.96427 -2.2574 CPDDVSHR 0 0 0 9.71339 0 0 0 0 0 0 10.0782 0 0 0 9.34283 9.41937 0 0 0 0 0 0 0 0 0 0 0 Q9H094 NBPF3_HUMAN Neuroblastoma breakpoint family member 3 (Protein AE2) (Protein SHIIIa4) NBPF3 L7 Homo sapiens (Human) cytoplasm [GO:0005737] 0.89061 -0.46502 LAEELGQAEELR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9688 0 0 0 0 0 0 0 0 12.0845 0 Q9H095 DRC9_HUMAN Dynein regulatory complex protein 9 (IQ domain-containing protein G) IQCG DRC9 Homo sapiens (Human) cilium organization [GO:0044782]; sperm axoneme assembly [GO:0007288]; spermatid development [GO:0007286] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; manchette [GO:0002177]; motile cilium [GO:0031514]; sperm flagellum [GO:0036126] calmodulin binding [GO:0005516]; Hsp70 protein binding [GO:0030544] 0.89868 -0.57047 KVKQDLLELK 0 0 0 0 0 0 0 0 0 0 0 0 11.3736 11.7129 0 0 11.8407 11.218 9.40977 0 0 0 0 0 0 0 0 Q9H098 F107B_HUMAN Protein FAM107B FAM107B C10orf45 Homo sapiens (Human) 0.91477 -0.83119 ELLMNQKR 0 0 0 0 0 0 0 0 0 0 0 0 9.64369 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H0A0 NAT10_HUMAN RNA cytidine acetyltransferase (EC 2.3.1.-) (18S rRNA cytosine acetyltransferase) (N-acetyltransferase 10) (N-acetyltransferase-like protein) (hALP) NAT10 ALP KIAA1709 Homo sapiens (Human) negative regulation of telomere maintenance via telomerase [GO:0032211]; positive regulation of translation [GO:0045727]; protein acetylation [GO:0006473]; regulation of centrosome duplication [GO:0010824]; ribosomal small subunit biogenesis [GO:0042274]; rRNA acetylation involved in maturation of SSU-rRNA [GO:1904812]; rRNA modification [GO:0000154]; tRNA acetylation [GO:0051391] "chromosome, telomeric region [GO:0000781]; membrane [GO:0016020]; midbody [GO:0030496]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; small-subunit processome [GO:0032040]; telomerase holoenzyme complex [GO:0005697]" ATP binding [GO:0005524]; DNA polymerase binding [GO:0070182]; mRNA N-acetyltransferase activity [GO:0106162]; N-acetyltransferase activity [GO:0008080]; RNA binding [GO:0003723]; rRNA cytidine N-acetyltransferase activity [GO:1990883]; tRNA binding [GO:0000049] 0.88429 -0.15583 DTLFCYHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.85891 0 0 0 0 0 0 0 0 0 0 0 0 Q9H0A6 RNF32_HUMAN RING finger protein 32 RNF32 FKSG33 HSD15 Homo sapiens (Human) aggresome [GO:0016235]; cytosol [GO:0005829]; endosome [GO:0005768]; nuclear body [GO:0016604] metal ion binding [GO:0046872] 0.92415 -1.0341 CGHEITEEEWEK 0 0 0 0 0 0 0 0 11.7771 0 14.5429 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H0A9 SPC1L_HUMAN Speriolin-like protein (Spermatogenesis and centriole-associated protein 1-like protein) SPATC1L C21orf56 Homo sapiens (Human) actin polymerization or depolymerization [GO:0008154]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of protein kinase A signaling [GO:0010739]; spermatogenesis [GO:0007283] centrosome [GO:0005813]; sperm connecting piece [GO:0097224] identical protein binding [GO:0042802]; protein kinase A regulatory subunit binding [GO:0034237] 0.96233 -2.4857 LEKLGYSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.57824 0 0 0 0 0 0 0 Q9H0B3 IQCN_HUMAN IQ domain-containing protein N IQCN KIAA1683 Homo sapiens (Human) spermatid development [GO:0007286] mitochondrion [GO:0005739]; nucleus [GO:0005634] 0.92356 -1.0468 AAAELPLEAEK 0 11.126 0 9.91341 0 0 0 0 0 0 10.5415 0 9.10415 0 0 0 0 9.8769 0 0 0 0 0 0 0 0 0 Q9H0B6 KLC2_HUMAN Kinesin light chain 2 (KLC 2) KLC2 Homo sapiens (Human) lysosome localization [GO:0032418]; microtubule-based movement [GO:0007018] cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinesin complex [GO:0005871]; kinesin I complex [GO:0016938]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] cadherin binding [GO:0045296]; kinesin binding [GO:0019894] 0.3083 0.7993 AEEVEYYYRR 10.5203 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.32105 0 0 0 Q9H0B8 CRLD2_HUMAN Cysteine-rich secretory protein LCCL domain-containing 2 (Cysteine-rich secretory protein 11) (CRISP-11) (LCCL domain-containing cysteine-rich secretory protein 2) CRISPLD2 CRISP11 LCRISP2 UNQ2914/PRO1156/PRO9783 Homo sapiens (Human) extracellular matrix organization [GO:0030198]; face morphogenesis [GO:0060325]; lung development [GO:0030324] extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; transport vesicle [GO:0030133] glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201] 0.95468 -1.5085 AFRIFAVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.0155 0 0 0 0 0 0 0 0 Q9H0C1 ZMY12_HUMAN Zinc finger MYND domain-containing protein 12 ZMYND12 Homo sapiens (Human) metal ion binding [GO:0046872] 0.89847 -0.56044 KNYEEAR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8916 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H0C2 ADT4_HUMAN "ADP/ATP translocase 4 (ADP,ATP carrier protein 4) (Adenine nucleotide translocator 4) (ANT 4) (Solute carrier family 25 member 31) (Sperm flagellar energy carrier protein)" SLC25A31 AAC4 ANT4 SFEC Homo sapiens (Human) cell differentiation [GO:0030154]; male meiosis I [GO:0007141]; mitochondrial ADP transmembrane transport [GO:0140021]; mitochondrial ATP transmembrane transport [GO:1990544]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; regulation of mitochondrial membrane permeability [GO:0046902]; spermatogenesis [GO:0007283] membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial permeability transition pore complex [GO:0005757]; mitochondrion [GO:0005739]; motile cilium [GO:0031514]; nucleus [GO:0005634]; plasma membrane [GO:0005886] ATP:ADP antiporter activity [GO:0005471] 0.95281 -1.4636 GMVDCLVRIPR 0 0 0 0 0 0 0 0 0 10.0403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H0C3 TM117_HUMAN Transmembrane protein 117 TMEM117 Homo sapiens (Human) intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059] endoplasmic reticulum [GO:0005783]; plasma membrane [GO:0005886] 0.93241 -1.2661 KSPSEHSKDMGITR 0 0 0 0 0 10.0591 11.2449 0 0 0 10.8369 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H0C5 BTBD1_HUMAN BTB/POZ domain-containing protein 1 (Hepatitis C virus NS5A-transactivated protein 8) (HCV NS5A-transactivated protein 8) BTBD1 C15orf1 NS5ATP8 Homo sapiens (Human) muscle organ development [GO:0007517]; neurogenesis [GO:0022008]; protein ubiquitination [GO:0016567]; regulation of protein binding [GO:0043393] cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; protein-containing complex [GO:0032991] cullin family protein binding [GO:0097602]; identical protein binding [GO:0042802] 0.90571 -0.72444 VEYIDRPRCCLR 0 0 0 0 0 0 0 0 0 0 0 10.6941 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H0C8 ILKAP_HUMAN Integrin-linked kinase-associated serine/threonine phosphatase 2C (ILKAP) (EC 3.1.3.16) ILKAP Homo sapiens (Human) protein dephosphorylation [GO:0006470] cytosol [GO:0005829]; nucleus [GO:0005634] metal ion binding [GO:0046872]; myosin phosphatase activity [GO:0017018] 0.96585 -2.3595 LANKAVQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2393 0 0 0 0 0 12.1925 0 Q9H0D2 ZN541_HUMAN Zinc finger protein 541 ZNF541 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-templated transcription [GO:0045892]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283] histone deacetylase complex [GO:0000118]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] metal ion binding [GO:0046872]; transcription corepressor activity [GO:0003714] 0.95608 -1.5944 ERPSHHPTPK 0 0 9.77292 0 0 0 0 0 0 0 11.0935 0 0 0 0 0 0 0 0 0 0 0 0 9.70181 0 0 0 Q9H0D6 XRN2_HUMAN 5'-3' exoribonuclease 2 (EC 3.1.13.-) (DHM1-like protein) (DHP protein) XRN2 Homo sapiens (Human) hippocampus development [GO:0021766]; mRNA processing [GO:0006397]; neuron differentiation [GO:0030182]; nuclear-transcribed mRNA catabolic process [GO:0000956]; retina development in camera-type eye [GO:0060041]; RNA catabolic process [GO:0006401]; RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]; rRNA processing [GO:0006364]; spermatogenesis [GO:0007283]; termination of RNA polymerase II transcription [GO:0006369] aggresome [GO:0016235]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 3'-5'-RNA exonuclease activity [GO:0000175]; 5'-3' exonuclease activity [GO:0008409]; 5'-3' RNA exonuclease activity [GO:0004534]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; RNA binding [GO:0003723]; transcription termination site sequence-specific DNA binding [GO:0001147] 0.96982 -5.0072 CLRYYIADR 0 0 0 0 0 0 0 10.2848 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7393 0 0 0 Q9H0E3 SP130_HUMAN Histone deacetylase complex subunit SAP130 (130 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p130) SAP130 Homo sapiens (Human) negative regulation of cell migration [GO:0030336]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of stem cell population maintenance [GO:1902459] nuclear speck [GO:0016607]; nucleus [GO:0005634]; Sin3 complex [GO:0016580]; Sin3-type complex [GO:0070822] 0.89205 -0.51046 INELIQGNMQR 0 9.36715 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H0E7 UBP44_HUMAN Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.4.19.12) (Deubiquitinating enzyme 44) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) USP44 Homo sapiens (Human) antiviral innate immune response [GO:0140374]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; negative regulation of mitotic metaphase/anaphase transition [GO:0045841]; negative regulation of ubiquitin protein ligase activity [GO:1904667]; nucleotide-excision repair [GO:0006289]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090266]; regulatory T cell differentiation [GO:0045066] chromatin [GO:0000785]; cytoplasm [GO:0005737]; mitotic spindle [GO:0072686]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] cysteine-type deubiquitinase activity [GO:0004843]; deubiquitinase activity [GO:0101005]; zinc ion binding [GO:0008270] 0.91935 -0.89248 QELEYQVK 0 0 0 0 0 0 0 0 0 0 10.1119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H0E9 BRD8_HUMAN Bromodomain-containing protein 8 (Skeletal muscle abundant protein) (Skeletal muscle abundant protein 2) (Thyroid hormone receptor coactivating protein of 120 kDa) (TrCP120) (p120) BRD8 SMAP SMAP2 Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; cellular response to thyroid hormone stimulus [GO:0097067]; chromatin organization [GO:0006325]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of double-strand break repair [GO:2000779] mitochondrion [GO:0005739]; NuA4 histone acetyltransferase complex [GO:0035267]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; Swr1 complex [GO:0000812] nuclear receptor coactivator activity [GO:0030374]; nuclear thyroid hormone receptor binding [GO:0046966] 0.31895 0.78985 APSIDGK 0 0 0 0 0 0 0 0 0 0 0 0 0 8.39601 0 0 10.0272 9.44545 8.49725 9.40035 0 9.19259 0 0 0 9.08377 9.06269 Q9H0G5 NSRP1_HUMAN Nuclear speckle splicing regulatory protein 1 (Coiled-coil domain-containing protein 55) (Nuclear speckle-related protein 70) (NSrp70) NSRP1 CCDC55 NSRP70 Homo sapiens (Human) "developmental process [GO:0032502]; in utero embryonic development [GO:0001701]; mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]" nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] mRNA binding [GO:0003729]; RNA binding [GO:0003723] 0.96901 -4.5265 AKEEHMK 0 0 0 0 0 8.98219 0 0 0 0 8.23036 10.4667 0 0 0 0 0 9.13758 10.2831 0 8.83469 8.54998 0 8.48643 0 0 0 Q9H0H5 RGAP1_HUMAN Rac GTPase-activating protein 1 (Male germ cell RacGap) (MgcRacGAP) (Protein CYK4 homolog) (CYK4) (HsCYK-4) RACGAP1 KIAA1478 MGCRACGAP Homo sapiens (Human) actomyosin contractile ring assembly [GO:0000915]; erythrocyte differentiation [GO:0030218]; mitotic cytokinesis [GO:0000281]; mitotic spindle midzone assembly [GO:0051256]; monoatomic ion transport [GO:0006811]; neuroblast proliferation [GO:0007405]; positive regulation of cytokinesis [GO:0032467]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of embryonic development [GO:0045995]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; spermatogenesis [GO:0007283]; sulfate transport [GO:0008272] acrosomal vesicle [GO:0001669]; centralspindlin complex [GO:0097149]; cleavage furrow [GO:0032154]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; Flemming body [GO:0090543]; microtubule [GO:0005874]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819]; spindle midzone [GO:0051233] "alpha-tubulin binding [GO:0043014]; beta-tubulin binding [GO:0048487]; gamma-tubulin binding [GO:0043015]; GTPase activator activity [GO:0005096]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; protein kinase binding [GO:0019901]" 0.95958 -1.7172 ISGCDRTVK 0 0 0 11.1314 11.1083 11.2088 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.33898 0 9.60783 9.19894 0 0 10.8066 Q9H0I2 ENKD1_HUMAN Enkurin domain-containing protein 1 ENKD1 C16orf48 UNQ6410/PRO21183 Homo sapiens (Human) establishment of mitotic spindle orientation [GO:0000132]; motile cilium assembly [GO:0044458]; non-motile cilium assembly [GO:1905515] 9+0 non-motile cilium [GO:0097731]; centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary base [GO:0097546]; cytoplasmic microtubule [GO:0005881]; microtubule cytoskeleton [GO:0015630]; spindle pole [GO:0000922] alpha-tubulin binding [GO:0043014]; microtubule binding [GO:0008017] 0.92373 -1.0692 DLWRREAEAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1778 0 0 11.2011 0 0 0 Q9H0I3 CC113_HUMAN Coiled-coil domain-containing protein 113 CCDC113 HSPC065 Homo sapiens (Human) cilium assembly [GO:0060271] axoneme [GO:0005930]; centriolar satellite [GO:0034451]; ciliary basal body [GO:0036064]; protein-containing complex [GO:0032991] 0.89718 -0.53829 AMEIYLNLDK 0 9.09916 0 0 0 8.91139 9.21483 0 0 0 10.4216 0 0 0 0 0 0 0 0 0 0 8.86031 0 0 0 0 0 Q9H0J4 QRIC2_HUMAN Glutamine-rich protein 2 QRICH2 Homo sapiens (Human) cell projection assembly [GO:0030031]; flagellated sperm motility [GO:0030317]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059] cytoplasm [GO:0005737]; nuclear membrane [GO:0031965]; sperm flagellum [GO:0036126] 0.96949 -3.5173 ELAELRESQDR 9.70134 0 0 0 9.12565 8.60047 0 0 11.3584 0 0 0 0 11.2938 0 0 0 0 10.1127 9.56413 0 0 0 0 0 0 0 Q9H0J9 PAR12_HUMAN Protein mono-ADP-ribosyltransferase PARP12 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Poly [ADP-ribose] polymerase 12) (PARP-12) (Zinc finger CCCH domain-containing protein 1) PARP12 ZC3HDC1 Homo sapiens (Human) protein auto-ADP-ribosylation [GO:0070213] nucleus [GO:0005634] metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+- protein-cysteine ADP-ribosyltransferase activity [GO:0140803]; NAD+-protein ADP-ribosyltransferase activity [GO:1990404]; nucleotidyltransferase activity [GO:0016779]; RNA binding [GO:0003723] 0.89832 -0.56063 DAAYSHHYSK 0 0 0 0 0 8.05441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H0K4 RSH6A_HUMAN Radial spoke head protein 6 homolog A (Radial spoke head-like protein 1) RSPH6A RSHL1 Homo sapiens (Human) axoneme assembly [GO:0035082]; cilium movement [GO:0003341]; cilium movement involved in cell motility [GO:0060294]; manchette disassembly [GO:1905199]; motile cilium assembly [GO:0044458] axoneme [GO:0005930]; radial spoke [GO:0001534]; sperm flagellum [GO:0036126] 0.74478 0.31972 AVDIVPK 0 0 0 0 0 0 0 0 0 0 0 0 9.24693 0 9.34283 0 10.3622 0 0 0 0 0 0 0 9.53986 0 0 Q9H0K6 PUS7L_HUMAN Pseudouridylate synthase PUS7L (EC 5.4.99.-) (Pseudouridylate synthase 7 homolog-like protein) PUS7L Homo sapiens (Human) mRNA processing [GO:0006397]; mRNA pseudouridine synthesis [GO:1990481]; pseudouridine synthesis [GO:0001522] nucleus [GO:0005634] pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723] 0.95484 -1.6282 FTFKPDTNK 17.1063 0 0 0 0 0 0 0 0 0 10.1227 0 0 0 0 0 8.94307 14.9687 9.59137 0 0 0 0 0 0 0 0 Q9H0L4 CSTFT_HUMAN Cleavage stimulation factor subunit 2 tau variant (CF-1 64 kDa subunit tau variant) (Cleavage stimulation factor 64 kDa subunit tau variant) (CSTF 64 kDa subunit tau variant) (TauCstF-64) CSTF2T KIAA0689 Homo sapiens (Human) pre-mRNA cleavage required for polyadenylation [GO:0098789] intracellular membrane-bounded organelle [GO:0043231]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleoplasm [GO:0005654] mRNA binding [GO:0003729]; RNA binding [GO:0003723] 0.96332 -2.4411 DSRAMETR 8.78375 0 0 0 0 0 0 0 0 0 0 8.70099 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H0M0 WWP1_HUMAN NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 2.3.2.26) (Atrophin-1-interacting protein 5) (AIP5) (HECT-type E3 ubiquitin transferase WWP1) (TGIF-interacting ubiquitin ligase 1) (Tiul1) (WW domain-containing protein 1) WWP1 Homo sapiens (Human) central nervous system development [GO:0007417]; monoatomic ion transmembrane transport [GO:0034220]; negative regulation of DNA-templated transcription [GO:0045892]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; signal transduction [GO:0007165]; viral entry into host cell [GO:0046718] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ubiquitin ligase complex [GO:0000151] ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.92399 -1.0543 RRVYYVDHNTR 0 0 0 0 0 0 0 0 0 9.35968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H0P0 5NT3A_HUMAN Cytosolic 5'-nucleotidase 3A (EC 3.1.3.5) (7-methylguanosine phosphate-specific 5'-nucleotidase) (7-methylguanosine nucleotidase) (EC 3.1.3.91) (Cytosolic 5'-nucleotidase 3) (Cytosolic 5'-nucleotidase III) (cN-III) (Pyrimidine 5'-nucleotidase 1) (P5'N-1) (P5N-1) (PN-I) (Uridine 5'-monophosphate hydrolase 1) (p36) NT5C3A NT5C3 P5N1 UMPH1 HSPC233 Homo sapiens (Human) defense response to virus [GO:0051607]; nucleotide metabolic process [GO:0009117]; pyrimidine nucleoside metabolic process [GO:0006213] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654] 5'-nucleotidase activity [GO:0008253]; magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; tRNA 2'-phosphotransferase activity [GO:0000215]; XMP 5'-nucleosidase activity [GO:0106411] 0.8165 0.22099 IIEMMPEFQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5053 0 0 0 0 0 Q9H0R5 GBP3_HUMAN Guanylate-binding protein 3 (EC 3.6.5.-) (GTP-binding protein 3) (GBP-3) (Guanine nucleotide-binding protein 3) GBP3 Homo sapiens (Human) cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; cytolysis in another organism [GO:0051715]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of pyroptosis [GO:0140639] cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; perinuclear region of cytoplasm [GO:0048471] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803] 0.95079 -1.3838 MVEEMQIK 0 0 0 0 0 0 0 0 0 0 0 9.31524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H0R6 GATA_HUMAN "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial (Glu-AdT subunit A) (EC 6.3.5.7) (Glutaminyl-tRNA synthase-like protein 1)" QRSL1 Homo sapiens (Human) glutaminyl-tRNAGln biosynthesis via transamidation [GO:0070681]; mitochondrial translation [GO:0032543]; regulation of protein stability [GO:0031647] glutamyl-tRNA(Gln) amidotransferase complex [GO:0030956]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity [GO:0050567] 0.85106 0.16103 ENYENYFVKAQKVR 0 0 0 0 8.946 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.54175 0 0 0 0 0 0 10.5725 Q9H0S4 DDX47_HUMAN Probable ATP-dependent RNA helicase DDX47 (EC 3.6.4.13) (DEAD box protein 47) DDX47 Homo sapiens (Human) extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380]; rRNA processing [GO:0006364] membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.92376 -0.99219 CAVSSKYQTVEK 0 0 0 0 0 0 0 0 0 9.60086 10.227 11.4781 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H0T7 RAB17_HUMAN Ras-related protein Rab-17 RAB17 Homo sapiens (Human) cilium assembly [GO:0060271]; endocytic recycling [GO:0032456]; endocytosis [GO:0006897]; establishment of melanosome localization [GO:0032401]; filopodium assembly [GO:0046847]; immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor [GO:0002415]; intracellular protein transport [GO:0006886]; melanosome transport [GO:0032402]; regulation of dendrite development [GO:0050773]; regulation of endocytosis [GO:0030100]; regulation of filopodium assembly [GO:0051489]; regulation of synapse assembly [GO:0051963]; transcytosis [GO:0045056] apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; dendrite [GO:0030425]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; melanosome [GO:0042470]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038] GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.92435 -1.1712 EVTFQEGKEFADSQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.79269 0 0 10.0606 0 Q9H0U4 RAB1B_HUMAN Ras-related protein Rab-1B (EC 3.6.5.2) RAB1B Homo sapiens (Human) autophagosome assembly [GO:0000045]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; positive regulation of glycoprotein metabolic process [GO:1903020]; regulation of autophagosome assembly [GO:2000785]; virion assembly [GO:0019068] cytosol [GO:0005829]; endomembrane system [GO:0012505]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; perinuclear region of cytoplasm [GO:0048471]; phagophore assembly site membrane [GO:0034045]; transport vesicle [GO:0030133] G protein activity [GO:0003925]; GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0 21.513 EFADSLGIPFLETSAK 9.76678 0 0 11.1583 0 0 0 0 9.71051 0 0 12.957 0 0 0 9.95569 0 0 0 0 0 0 10.6225 0 10.9189 9.23213 11.1331 Q9H0W5 CCDC8_HUMAN Coiled-coil domain-containing protein 8 CCDC8 Homo sapiens (Human) microtubule cytoskeleton organization [GO:0000226]; regulation of mitotic nuclear division [GO:0007088] 3M complex [GO:1990393]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] 0.9277 -1.2251 DKSRQGPR 0 0 0 0 0 0 0 0 0 10.4008 0 0 0 0 10.1746 0 0 0 0 0 0 9.28981 0 0 0 0 0 Q9H0W7 THAP2_HUMAN THAP domain-containing protein 2 THAP2 Homo sapiens (Human) nucleolus [GO:0005730]; nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.8985 -0.61748 FPLDPKRR 0 0 0 0 0 0 0 0 0 0 10.5994 0 10.5571 10.6437 0 0 0 10.428 11.3431 11.4184 11.3514 11.1828 0 11.2011 0 0 0 Q9H0W8 SMG9_HUMAN Nonsense-mediated mRNA decay factor SMG9 SMG9 C19orf61 Homo sapiens (Human) "brain development [GO:0007420]; eye development [GO:0001654]; heart development [GO:0007507]; in utero embryonic development [GO:0001701]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]" cytosol [GO:0005829] identical protein binding [GO:0042802] 0.87722 -0.003889 SSALAEYSR 0 0 0 0 0 0 0 0 9.68946 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H0X9 OSBL5_HUMAN Oxysterol-binding protein-related protein 5 (ORP-5) (OSBP-related protein 5) (Oxysterol-binding protein homolog 1) OSBPL5 KIAA1534 OBPH1 ORP5 Homo sapiens (Human) cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; Golgi to plasma membrane transport [GO:0006893]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid transport [GO:0015914] cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-plasma membrane contact site [GO:0140268]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020] cholesterol binding [GO:0015485]; oxysterol binding [GO:0008142]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylserine binding [GO:0001786]; phosphatidylserine transfer activity [GO:0140343]; phospholipid transporter activity [GO:0005548]; sterol binding [GO:0032934]; sterol transporter activity [GO:0015248] 0.92033 -1.141 ATQEKFALEEAQRQR 10.1489 0 9.77602 0 0 0 10.5248 10.2904 10.2743 11.6808 0 0 0 0 0 0 0 0 0 10.3487 0 0 0 0 0 0 0 Q9H114 CSTL1_HUMAN Cystatin-like 1 (RCET11) CSTL1 Homo sapiens (Human) negative regulation of peptidase activity [GO:0010466] extracellular region [GO:0005576] cysteine-type endopeptidase inhibitor activity [GO:0004869] 0.96892 -3.3761 WEGFQQK 0 0 0 0 0 0 0 8.38914 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H115 SNAB_HUMAN Beta-soluble NSF attachment protein (SNAP-beta) (N-ethylmaleimide-sensitive factor attachment protein beta) NAPB SNAPB Homo sapiens (Human) "intracellular protein transport [GO:0006886]; regulation of synaptic vesicle priming [GO:0010807]; SNARE complex disassembly [GO:0035494]; synaptic transmission, glutamatergic [GO:0035249]" extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; synaptobrevin 2-SNAP-25-syntaxin-1a complex [GO:0070044] soluble NSF attachment protein activity [GO:0005483]; syntaxin binding [GO:0019905] 0.47505 0.62661 EAVQLMAEAEKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.65691 0 Q9H116 GZF1_HUMAN GDNF-inducible zinc finger protein 1 (Zinc finger and BTB domain-containing protein 23) (Zinc finger protein 336) GZF1 ZBTB23 ZNF336 Homo sapiens (Human) branching involved in ureteric bud morphogenesis [GO:0001658]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]" 0.8718 0.06491 HVHSSERHFPCELCGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.79152 0 0 0 0 0 0 0 0 0 0 0 Q9H147 TDIF1_HUMAN Deoxynucleotidyltransferase terminal-interacting protein 1 (Terminal deoxynucleotidyltransferase-interacting factor 1) (TdIF1) (TdT-interacting factor 1) DNTTIP1 C20orf167 TDIF1 Homo sapiens (Human) chromosome [GO:0005694]; histone deacetylase complex [GO:0000118]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; nucleosome binding [GO:0031491]; protein homodimerization activity [GO:0042803] 0.95989 -1.8484 GRQAEEECAHRGSPLPK 0 0 0 10.2684 0 10.6235 0 0 0 0 0 0 0 0 0 0 0 0 9.80037 0 0 0 0 0 0 0 0 Q9H158 PCDC1_HUMAN Protocadherin alpha-C1 (PCDH-alpha-C1) PCDHAC1 Homo sapiens (Human) cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399] plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.84549 0.15372 TGHLVTK 0 0 0 0 0 0 0 0 0 9.19522 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H159 CAD19_HUMAN Cadherin-19 CDH19 CDH7L2 UNQ478/PRO941 Homo sapiens (Human) adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] adherens junction [GO:0005912]; catenin complex [GO:0016342] cadherin binding [GO:0045296]; calcium ion binding [GO:0005509] 0.35627 0.75329 KVDFEHQNHYGIR 0 0 0 0 0 0 0 0 0 0 10.2851 10.2397 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H161 ALX4_HUMAN Homeobox protein aristaless-like 4 ALX4 KIAA1788 Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; digestive tract development [GO:0048565]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic skeletal system morphogenesis [GO:0048704]; hair follicle development [GO:0001942]; muscle organ development [GO:0007517]; post-embryonic development [GO:0009791]; regulation of apoptotic process [GO:0042981]; regulation of transcription by RNA polymerase II [GO:0006357]; roof of mouth development [GO:0060021]; skeletal system development [GO:0001501] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; HMG box domain binding [GO:0071837]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.65723 0.39534 AFPGGDK 0 0 0 0 0 0 0 8.24203 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H165 BC11A_HUMAN B-cell lymphoma/leukemia 11A (BCL-11A) (B-cell CLL/lymphoma 11A) (COUP-TF-interacting protein 1) (Ecotropic viral integration site 9 protein homolog) (EVI-9) (Zinc finger protein 856) BCL11A CTIP1 EVI9 KIAA1809 ZNF856 Homo sapiens (Human) cellular response to L-glutamate [GO:1905232]; negative regulation of axon extension [GO:0030517]; negative regulation of branching morphogenesis of a nerve [GO:2000173]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendrite development [GO:2000171]; negative regulation of dendrite extension [GO:1903860]; negative regulation of neuron projection development [GO:0010977]; negative regulation of neuron remodeling [GO:1904800]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein sumoylation [GO:0016925]; regulation of dendrite development [GO:0050773]; regulation of transcription by RNA polymerase II [GO:0006357] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; postsynaptic density [GO:0014069]; SWI/SNF complex [GO:0016514] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor binding [GO:0140297]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; transcription coregulator activity [GO:0003712]; transcription regulatory region nucleic acid binding [GO:0001067]" 0.87239 0.031149 AVDKPPSPSPIEMK 0 0 0 0 0 0 0 9.57154 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H169 STMN4_HUMAN Stathmin-4 (Stathmin-like protein B3) (RB3) STMN4 Homo sapiens (Human) microtubule depolymerization [GO:0007019]; neuron projection development [GO:0031175]; regulation of microtubule polymerization or depolymerization [GO:0031110] cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; neuron projection [GO:0043005] tubulin binding [GO:0015631] 0.86425 0.085703 EVIQKAIEENNNFIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9075 0 Q9H171 ZBP1_HUMAN Z-DNA-binding protein 1 (DNA-dependent activator of IFN-regulatory factors) (DAI) (Tumor stroma and activated macrophage protein DLM-1) ZBP1 C20orf183 DLM1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; antiviral innate immune response [GO:0140374]; apoptotic process [GO:0006915]; defense response to fungus [GO:0050832]; defense response to virus [GO:0051607]; positive regulation of apoptotic process [GO:0043065]; positive regulation of inflammatory response [GO:0050729]; positive regulation of necroptotic process [GO:0060545]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; pyroptosis [GO:0070269]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-1-mediated signaling pathway [GO:2000659] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] DNA binding [GO:0003677]; double-stranded RNA adenosine deaminase activity [GO:0003726]; double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; left-handed Z-DNA binding [GO:0003692]; RNA binding [GO:0003723] 0.96538 -2.2902 DVNRDLYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.42438 0 0 0 0 0 Q9H175 CSRN2_HUMAN Cysteine/serine-rich nuclear protein 2 (CSRNP-2) (Protein FAM130A1) (TGF-beta-induced apoptosis protein 12) (TAIP-12) CSRNP2 C12orf22 FAM130A1 TAIP12 Homo sapiens (Human) apoptotic process [GO:0006915]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; phosphatase binding [GO:0019902]; sequence-specific DNA binding [GO:0043565]" 0.94657 -1.352 LHAKKMK 0 0 0 0 0 0 0 0 0 12.3281 0 0 0 10.4419 0 0 0 0 10.6852 0 0 11.3915 11.4367 0 0 0 0 Q9H190 SDCB2_HUMAN Syntenin-2 (Similar to TACIP18) (SITAC) (Syndecan-binding protein 2) SDCBP2 SITAC18 Homo sapiens (Human) cell population proliferation [GO:0008283]; intracellular signal transduction [GO:0035556]; intracellular transport [GO:0046907]; nervous system development [GO:0007399] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] "identical protein binding [GO:0042802]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]" 0.9241 -1.0487 EIHLCKDER 0 0 0 0 0 0 0 0 0 0 8.84172 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5995 Q9H1A3 METL9_HUMAN Protein-L-histidine N-pros-methyltransferase (EC 2.1.1.-) (DORA reverse strand protein) (DREV) (DREV1) (Methyltransferase-like protein 9) (hMETTL9) METTL9 DREV CGI-81 Homo sapiens (Human) methylation [GO:0032259] endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739] protein-L-histidine N-pros-methyltransferase activity [GO:0106370] 0.20884 0.91113 DIRSVLEPTRGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0614 0 10.2021 0 9.59751 0 10.4466 Q9H1A4 APC1_HUMAN Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein) ANAPC1 TSG24 Homo sapiens (Human) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; protein K11-linked ubiquitination [GO:0070979]; regulation of meiotic cell cycle [GO:0051445]; regulation of mitotic cell cycle [GO:0007346] anaphase-promoting complex [GO:0005680]; cytosol [GO:0005829]; nucleoplasm [GO:0005654] molecular adaptor activity [GO:0060090] 0.59008 0.4635 DLETLPFGIALPIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.28432 0 0 0 0 0 0 0 0 0 0 0 Q9H1B7 I2BPL_HUMAN Probable E3 ubiquitin-protein ligase IRF2BPL (EC 2.3.2.27) (Enhanced at puberty protein 1) (Interferon regulatory factor 2-binding protein-like) IRF2BPL C14orf4 EAP1 KIAA1865 My039 Homo sapiens (Human) development of secondary female sexual characteristics [GO:0046543]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein ubiquitination [GO:0016567] extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630] 0.89756 -0.58286 LGEEQQR 0 0 8.6566 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.43187 0 0 0 0 0 Q9H1D0 TRPV6_HUMAN Transient receptor potential cation channel subfamily V member 6 (TrpV6) (CaT-like) (CaT-L) (Calcium transport protein 1) (CaT1) (Epithelial calcium channel 2) (ECaC2) TRPV6 ECAC2 Homo sapiens (Human) calcium ion homeostasis [GO:0055074]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; parathyroid hormone secretion [GO:0035898]; regulation of calcium ion-dependent exocytosis [GO:0017158]; response to calcium ion [GO:0051592] calcium channel complex [GO:0034704]; plasma membrane [GO:0005886] calcium channel activity [GO:0005262]; calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872] 0.92656 -1.186 ATGTAFR 0 0 0 0 0 0 10.1916 10.0471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.15826 0 0 0 0 Q9H1D9 RPC6_HUMAN DNA-directed RNA polymerase III subunit RPC6 (RNA polymerase III subunit C6) (DNA-directed RNA polymerase III subunit F) (RNA polymerase III 39 kDa subunit) (RPC39) POLR3F Homo sapiens (Human) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728]; regulation of transcription by RNA polymerase III [GO:0006359]; transcription by RNA polymerase III [GO:0006383] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; RNA polymerase III complex [GO:0005666] DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; double-stranded DNA binding [GO:0003690] 0.78162 0.26139 EGTVGSVDGHMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.10045 11.7671 0 0 0 0 0 0 0 0 0 0 0 Q9H1E1 RNAS7_HUMAN Ribonuclease 7 (RNase 7) (EC 3.1.27.-) (Skin-derived antimicrobial protein 2) (SAP-2) RNASE7 UNQ2516/PRO6006 Homo sapiens (Human) antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytolysis in another organism [GO:0051715]; defense response to fungus [GO:0050832]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087] cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615] endonuclease activity [GO:0004519]; lipopolysaccharide binding [GO:0001530]; nucleic acid binding [GO:0003676]; peptidoglycan binding [GO:0042834]; RNA nuclease activity [GO:0004540] 0.95262 -1.4937 LTSGKHPNCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.79534 0 0 0 0 0 Q9H1E3 NUCKS_HUMAN Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 (P1) NUCKS1 NUCKS JC7 Homo sapiens (Human) cellular response to X-ray [GO:0071481]; chromatin organization [GO:0006325]; double-strand break repair via homologous recombination [GO:0000724]; gene conversion [GO:0035822]; interstrand cross-link repair [GO:0036297]; intracellular glucose homeostasis [GO:0001678]; modulation by host of RNA binding by virus [GO:1990968]; modulation by host of viral genome replication [GO:0044827]; modulation by host of viral RNA-binding transcription factor activity [GO:1990969]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA replication [GO:0006275]; regulation of DNA strand elongation [GO:0060382]; regulation of insulin receptor signaling pathway [GO:0046626]; replication fork processing [GO:0031297] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; DNA-binding transcription factor binding [GO:0140297]; double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; transcription coactivator activity [GO:0003713] 0.0099751 1.8525 ATVTPSPVK 0 0 0 0 0 0 0 0 0 8.34403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H1H9 KI13A_HUMAN Kinesin-like protein KIF13A (Kinesin-like protein RBKIN) KIF13A RBKIN Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; cytoskeleton-dependent intracellular transport [GO:0030705]; endosome to lysosome transport [GO:0008333]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; melanosome organization [GO:0032438]; microtubule-based movement [GO:0007018]; plus-end-directed vesicle transport along microtubule [GO:0072383]; regulation of cytokinesis [GO:0032465]; vesicle cargo loading [GO:0035459] centrosome [GO:0005813]; endosome membrane [GO:0010008]; Golgi membrane [GO:0000139]; kinesin complex [GO:0005871]; microtubule [GO:0005874]; midbody [GO:0030496]; trans-Golgi network membrane [GO:0032588] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777] 0.80954 0.23317 AFSPQPPK 0 0 0 0 0 0 0 0 0 0 8.98513 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H1J5 WNT8A_HUMAN Protein Wnt-8a (Protein Wnt-8d) WNT8A WNT8D Homo sapiens (Human) anterior/posterior axis specification [GO:0009948]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment [GO:0061317]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; cell fate commitment [GO:0045165]; neural crest cell fate commitment [GO:0014034]; neuron differentiation [GO:0030182]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to retinoic acid [GO:0032526]; secondary palate development [GO:0062009] collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615] cytokine activity [GO:0005125]; frizzled binding [GO:0005109]; receptor ligand activity [GO:0048018] 0.87097 0.062281 ALMNLHNNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.39752 0 0 0 0 0 0 0 0 0 0 Q9H1K4 GHC2_HUMAN Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+) symporter 2) (Solute carrier family 25 member 18) SLC25A18 GC2 Homo sapiens (Human) aspartate transmembrane transport [GO:0015810]; L-glutamate transmembrane transport [GO:0015813]; malate-aspartate shuttle [GO:0043490]; monoatomic ion transport [GO:0006811] mitochondrial inner membrane [GO:0005743] amino acid:proton symporter activity [GO:0005280]; L-aspartate transmembrane transporter activity [GO:0015183]; L-glutamate transmembrane transporter activity [GO:0005313] 0.88424 -0.29641 LLMEDGMQRNLK 0 0 0 0 0 0 0 0 0 0 8.65996 0 0 0 0 0 0 0 0 9.28364 0 0 0 0 9.97269 10.0136 10.115 Q9H1K6 TLRN1_HUMAN Talin rod domain-containing protein 1 (Mesoderm development candidate 1) TLNRD1 MESDC1 Homo sapiens (Human) stress fiber [GO:0001725] actin binding [GO:0003779]; identical protein binding [GO:0042802] 0.96736 -2.8524 FLTDACALASDKSRDR 0 0 0 0 0 0 0 0 0 0 10.8875 0 0 0 0 0 0 0 0 0 0 0 9.20474 0 0 0 0 Q9H1P3 OSBL2_HUMAN Oxysterol-binding protein-related protein 2 (ORP-2) (OSBP-related protein 2) OSBPL2 KIAA0772 ORP2 Homo sapiens (Human) bile acid biosynthetic process [GO:0006699]; cholesterol transport [GO:0030301]; intracellular cholesterol transport [GO:0032367]; phospholipid transport [GO:0015914]; plasma membrane organization [GO:0007009]; protein homotetramerization [GO:0051289] cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020] "cholesterol binding [GO:0015485]; cholesterol transfer activity [GO:0120020]; phosphatidylinositol transfer activity [GO:0008526]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; sterol transporter activity [GO:0015248]" 0.61011 0.43254 TSLPAPMFSRSDFSVWTILK 13.0189 0 12.76 12.7973 0 0 12.4528 0 0 0 0 0 12.3856 12.78 12.8249 0 13.269 0 0 0 12.3188 12.0588 0 0 13.5895 0 0 Q9H1R3 MYLK2_HUMAN "Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2) (EC 2.7.11.18)" MYLK2 Homo sapiens (Human) cardiac muscle contraction [GO:0060048]; cardiac muscle tissue morphogenesis [GO:0055008]; neuromuscular synaptic transmission [GO:0007274]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of gene expression [GO:0010628]; protein autophosphorylation [GO:0046777]; regulation of muscle filament sliding [GO:0032971]; skeletal muscle cell differentiation [GO:0035914]; skeletal muscle satellite cell differentiation [GO:0014816]; striated muscle contraction [GO:0006941] cytoplasm [GO:0005737]; nucleus [GO:0005634]; sarcomere [GO:0030017]; synapse [GO:0045202] ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; myosin light chain binding [GO:0032027]; myosin light chain kinase activity [GO:0004687] 0.90752 -0.73742 APDPPTLKK 0 0 0 0 8.24332 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H1V8 S6A17_HUMAN Sodium-dependent neutral amino acid transporter SLC6A17 (Sodium-dependent neurotransmitter transporter NTT4) (Solute carrier family 6 member 17) SLC6A17 NTT4 Homo sapiens (Human) alanine transport [GO:0032328]; brain development [GO:0007420]; glycine transport [GO:0015816]; leucine transport [GO:0015820]; neurotransmitter transport [GO:0006836]; neutral amino acid transport [GO:0015804]; proline transport [GO:0015824]; protein catabolic process [GO:0030163]; sodium ion transmembrane transport [GO:0035725]; transport across blood-brain barrier [GO:0150104] cell projection [GO:0042995]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672] symporter activity [GO:0015293] 0.87113 0.037848 FYFYMWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.81553 0 0 0 0 0 0 0 0 0 0 0 0 Q9H1X1 RSPH9_HUMAN Radial spoke head protein 9 homolog RSPH9 C6orf206 MRPS18AL1 Homo sapiens (Human) axonemal central apparatus assembly [GO:1904158]; axoneme assembly [GO:0035082]; cilium movement [GO:0003341]; cilium movement involved in cell motility [GO:0060294]; motile cilium assembly [GO:0044458]; radial spoke assembly [GO:0062177] 9+2 motile cilium [GO:0097729]; axoneme [GO:0005930]; kinocilium [GO:0060091]; motile cilium [GO:0031514] 0.94992 -1.3838 LSSYFHFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.80951 0 0 0 0 0 0 0 0 0 Q9H1X3 DJC25_HUMAN DnaJ homolog subfamily C member 25 DNAJC25 Homo sapiens (Human) protein folding [GO:0006457] endoplasmic reticulum membrane [GO:0005789] 0.5243 0.58712 KDYDYMLDHPEEYYSHYYHYYSR 9.97183 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H1Z4 WDR13_HUMAN WD repeat-containing protein 13 WDR13 Homo sapiens (Human) negative regulation of type B pancreatic cell proliferation [GO:1904691] centriolar satellite [GO:0034451]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] promoter-specific chromatin binding [GO:1990841] 0.52385 0.58764 SFPIEQSSHPVR 0 0 0 9.04617 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9272 0 Q9H1Z8 AUGN_HUMAN Augurin (Esophageal cancer-related gene 4 protein) (ECRG4) ECRG4 C2orf40 UNQ761/PRO1508 Homo sapiens (Human) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular senescence [GO:0090398]; central nervous system development [GO:0007417]; G1 to G0 transition [GO:0070314]; negative regulation of cell population proliferation [GO:0008285]; neuropeptide signaling pathway [GO:0007218]; positive regulation of corticosterone secretion [GO:2000854]; positive regulation of corticotropin secretion [GO:0051461]; positive regulation of corticotropin-releasing hormone secretion [GO:0051466]; regulation of cell population proliferation [GO:0042127]; response to wounding [GO:0009611]; vasopressin secretion [GO:0030103] apical plasma membrane [GO:0016324]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; extracellular space [GO:0005615] neuropeptide hormone activity [GO:0005184] 0.92114 -1.1064 VAVDENKAK 0 0 0 0 0 0 0 0 0 9.62273 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H1Z9 TSN10_HUMAN Tetraspanin-10 (Tspan-10) (Oculospanin) TSPAN10 OCSP Homo sapiens (Human) establishment of protein localization to organelle [GO:0072594] membrane [GO:0016020] enzyme binding [GO:0019899] 0.8119 0.22212 VVYLEGCGPPLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.5615 0 0 0 0 0 0 0 0 0 0 0 0 Q9H201 EPN3_HUMAN Epsin-3 (EPS-15-interacting protein 3) EPN3 Homo sapiens (Human) endocytosis [GO:0006897] clathrin vesicle coat [GO:0030125]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of plasma membrane [GO:0019897]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] clathrin binding [GO:0030276]; EH domain binding [GO:1990175]; phospholipid binding [GO:0005543] 0.9144 -0.77789 ALTLLDYLLKTGSER 0 0 11.9776 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H211 CDT1_HUMAN DNA replication factor Cdt1 (Double parked homolog) (DUP) CDT1 Homo sapiens (Human) attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; cell division [GO:0051301]; DNA replication checkpoint signaling [GO:0000076]; DNA replication preinitiation complex assembly [GO:0071163]; mitotic cell cycle [GO:0000278]; negative regulation of cell cycle [GO:0045786]; negative regulation of DNA-templated DNA replication [GO:2000104]; positive regulation of chromatin binding [GO:0035563]; positive regulation of DNA replication [GO:0045740]; positive regulation of DNA-templated DNA replication [GO:2000105]; regulation of DNA replication origin binding [GO:1902595]; regulation of DNA-templated DNA replication initiation [GO:0030174]; regulation of nuclear cell cycle DNA replication [GO:0033262]; response to sorbitol [GO:0072708] kinetochore [GO:0000776]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA polymerase binding [GO:0070182] 0.8097 0.22623 SMDTIVGMLHNRSETPTFAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.63557 0 0 0 0 0 0 Q9H228 S1PR5_HUMAN Sphingosine 1-phosphate receptor 5 (S1P receptor 5) (S1P5) (Endothelial differentiation G-protein-coupled receptor 8) (Sphingosine 1-phosphate receptor Edg-8) (S1P receptor Edg-8) S1PR5 EDG8 Homo sapiens (Human) regulation of neuron differentiation [GO:0045664] plasma membrane [GO:0005886] sphingosine-1-phosphate receptor activity [GO:0038036] 0.94771 -1.3541 HALLRLVCCGRHSCGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1844 0 0 0 0 0 0 0 0 0 Q9H237 PORCN_HUMAN Protein-serine O-palmitoleoyltransferase porcupine (EC 2.3.1.250) (Protein MG61) PORCN MG61 PORC PPN Homo sapiens (Human) glycoprotein metabolic process [GO:0009100]; lipid modification [GO:0030258]; protein lipidation [GO:0006497]; protein palmitoleylation [GO:0045234]; protein palmitoylation [GO:0018345]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; Wnt protein secretion [GO:0061355]; Wnt signaling pathway [GO:0016055] AMPA glutamate receptor complex [GO:0032281]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020] palmitoleoyltransferase activity [GO:1990698]; Wnt-protein binding [GO:0017147] 0.94279 -1.3327 KARGTMVR 0 0 0 0 0 9.87064 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H239 MMP28_HUMAN Matrix metalloproteinase-28 (MMP-28) (EC 3.4.24.-) (Epilysin) MMP28 MMP25 UNQ1893/PRO4339 Homo sapiens (Human) collagen catabolic process [GO:0030574]; extracellular matrix organization [GO:0030198]; negative regulation of macrophage chemotaxis [GO:0010760]; proteolysis [GO:0006508] collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576] metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270] 0.5597 0.51829 EAEAFLEK 0 0 0 0 0 0 0 0 0 0 9.94721 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H244 P2Y12_HUMAN P2Y purinoceptor 12 (P2Y12) (ADP-glucose receptor) (ADPG-R) (P2T(AC)) (P2Y(AC)) (P2Y(cyc)) (P2Y12 platelet ADP receptor) (P2Y(ADP)) (SP1999) P2RY12 HORK3 Homo sapiens (Human) "activation of phospholipase C activity [GO:0007202]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; calcium-mediated signaling [GO:0019722]; calcium-mediated signaling using extracellular calcium source [GO:0035585]; cell projection organization [GO:0030030]; cellular response to ATP [GO:0071318]; cytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration [GO:0021808]; establishment of localization in cell [GO:0051649]; G protein-coupled receptor signaling pathway [GO:0007186]; hemostasis [GO:0007599]; lamellipodium assembly [GO:0030032]; monoatomic ion transport [GO:0006811]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of chemotaxis [GO:0050921]; positive regulation of integrin activation by cell surface receptor linked signal transduction [GO:0033626]; positive regulation of microglial cell migration [GO:1904141]; positive regulation of monoatomic ion transport [GO:0043270]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of ruffle assembly [GO:1900029]; regulation of chemotaxis [GO:0050920]; regulation of microglial cell migration [GO:1904139]; response to axon injury [GO:0048678]; substrate-dependent cell migration, cell extension [GO:0006930]; visual system development [GO:0150063]" cell body membrane [GO:0044298]; cell projection membrane [GO:0031253]; cell surface [GO:0009986]; membrane [GO:0016020]; plasma membrane [GO:0005886] G protein-coupled adenosine receptor activity [GO:0001609]; G protein-coupled ADP receptor activity [GO:0001621]; G protein-coupled purinergic nucleotide receptor activity [GO:0045028]; guanyl-nucleotide exchange factor activity [GO:0005085] 0.91683 -0.84337 KEQDGGDPNEETPM 0 11.6713 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H251 CAD23_HUMAN Cadherin-23 (Otocadherin) CDH23 KIAA1774 KIAA1812 UNQ1894/PRO4340 Homo sapiens (Human) auditory receptor cell stereocilium organization [GO:0060088]; calcium ion transport [GO:0006816]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; equilibrioception [GO:0050957]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; locomotory behavior [GO:0007626]; photoreceptor cell maintenance [GO:0045494]; post-embryonic animal organ morphogenesis [GO:0048563]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] catenin complex [GO:0016342]; centrosome [GO:0005813]; cochlear hair cell ribbon synapse [GO:0098683]; kinocilium [GO:0060091]; membrane [GO:0016020]; photoreceptor inner segment [GO:0001917]; photoreceptor ribbon synapse [GO:0098684]; stereocilium [GO:0032420]; stereocilium tip [GO:0032426] cadherin binding [GO:0045296]; calcium ion binding [GO:0005509] 0.95902 -1.831 AEYTAGVATDAK 0 0 0 0 0 0 0 8.81602 0 0 0 0 10.2329 10.9834 0 0 0 0 0 0 0 0 0 0 9.82606 0 0 Q9H252 KCNH6_HUMAN Potassium voltage-gated channel subfamily H member 6 (Ether-a-go-go-related gene potassium channel 2) (ERG-2) (Eag-related protein 2) (Ether-a-go-go-related protein 2) (hERG-2) (hERG2) (Voltage-gated potassium channel subunit Kv11.2) KCNH6 ERG2 Homo sapiens (Human) membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of monoatomic ion transmembrane transport [GO:0034765]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307] plasma membrane [GO:0005886] inward rectifier potassium channel activity [GO:0005242] 0.69826 0.37514 IAVHYFK 0 0 0 0 9.58011 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5624 0 Q9H254 SPTN4_HUMAN "Spectrin beta chain, non-erythrocytic 4 (Beta-IV spectrin) (Spectrin, non-erythroid beta chain 3)" SPTBN4 KIAA1642 SPTBN3 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament capping [GO:0051693]; adult walking behavior [GO:0007628]; axonogenesis [GO:0007409]; cardiac conduction [GO:0061337]; central nervous system projection neuron axonogenesis [GO:0021952]; clustering of voltage-gated sodium channels [GO:0045162]; fertilization [GO:0009566]; negative regulation of heart rate [GO:0010459]; positive regulation of multicellular organism growth [GO:0040018]; protein localization to plasma membrane [GO:0072659]; regulation of peptidyl-serine phosphorylation [GO:0033135]; regulation of sodium ion transport [GO:0002028]; sensory perception of sound [GO:0007605]; transmission of nerve impulse [GO:0019226]; vesicle-mediated transport [GO:0016192] actin filament [GO:0005884]; axon hillock [GO:0043203]; axon initial segment [GO:0043194]; cell body fiber [GO:0070852]; cell junction [GO:0030054]; cell projection [GO:0042995]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercalated disc [GO:0014704]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; node of Ranvier [GO:0033268]; nuclear matrix [GO:0016363]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; PML body [GO:0016605]; spectrin [GO:0008091] actin binding [GO:0003779]; actin filament binding [GO:0051015]; ankyrin binding [GO:0030506]; cytoskeletal protein-membrane anchor activity [GO:0106006]; phosphatase binding [GO:0019902]; phospholipid binding [GO:0005543]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200] 0.96073 -2.0124 AEHEREAALR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.9407 0 0 0 0 0 0 9.89621 Q9H257 CARD9_HUMAN Caspase recruitment domain-containing protein 9 (hCARD9) CARD9 Homo sapiens (Human) antifungal innate immune response [GO:0061760]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; host-mediated regulation of intestinal microbiota composition [GO:0048874]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immunoglobulin mediated immune response [GO:0016064]; JNK cascade [GO:0007254]; neutrophil mediated immunity [GO:0002446]; positive regulation of chemokine production [GO:0032722]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of T-helper 17 type immune response [GO:2000318]; positive regulation of tumor necrosis factor production [GO:0032760]; protein homooligomerization [GO:0051260]; regulation of apoptotic process [GO:0042981]; regulation of interleukin-2 production [GO:0032663]; response to exogenous dsRNA [GO:0043330]; response to muramyl dipeptide [GO:0032495]; response to peptidoglycan [GO:0032494]; response to xenobiotic stimulus [GO:0009410] CBM complex [GO:0032449]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] CARD domain binding [GO:0050700]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621] 0.91782 -0.868 AEDDCKVERK 0 0 0 0 0 0 0 0 0 0 0 9.15026 10.5897 0 9.95993 0 0 0 0 0 0 0 0 0 0 0 0 Q9H267 VP33B_HUMAN Vacuolar protein sorting-associated protein 33B (hVPS33B) VPS33B Homo sapiens (Human) collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; endosome organization [GO:0007032]; intracellular protein transport [GO:0006886]; intracellular transport [GO:0046907]; lysosome localization [GO:0032418]; megakaryocyte development [GO:0035855]; melanosome localization [GO:0032400]; membrane fusion [GO:0061025]; peptidyl-lysine hydroxylation [GO:0017185]; phagosome-lysosome fusion [GO:0090385]; platelet alpha granule organization [GO:0070889]; protein transport [GO:0015031]; regulation of platelet aggregation [GO:0090330]; skin morphogenesis [GO:0043589]; vesicle-mediated transport [GO:0016192] clathrin-coated vesicle [GO:0030136]; CORVET complex [GO:0033263]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; HOPS complex [GO:0030897]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; perinuclear region of cytoplasm [GO:0048471]; platelet alpha granule [GO:0031091]; recycling endosome [GO:0055037]; vesicle tethering complex [GO:0099023] protein-containing complex binding [GO:0044877] 0.93013 -1.2394 KYKVIFSPQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.86556 0 0 0 0 0 Q9H269 VPS16_HUMAN Vacuolar protein sorting-associated protein 16 homolog (hVPS16) VPS16 Homo sapiens (Human) "autophagosome maturation [GO:0097352]; endosomal transport [GO:0016197]; endosomal vesicle fusion [GO:0034058]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; regulation of SNARE complex assembly [GO:0035542]; vacuole fusion, non-autophagic [GO:0042144]" autophagosome [GO:0005776]; axon [GO:0030424]; clathrin-coated vesicle [GO:0030136]; CORVET complex [GO:0033263]; early endosome [GO:0005769]; endosome [GO:0005768]; endosome membrane [GO:0010008]; HOPS complex [GO:0030897]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; neuronal cell body [GO:0043025]; presynapse [GO:0098793]; recycling endosome [GO:0055037] actin binding [GO:0003779]; actin filament binding [GO:0051015] 0.9677 -2.946 LLEYEPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2413 0 0 0 0 0 0 0 Q9H270 VPS11_HUMAN Vacuolar protein sorting-associated protein 11 homolog (hVPS11) (RING finger protein 108) VPS11 RNF108 PP3476 Homo sapiens (Human) autophagy [GO:0006914]; endosomal vesicle fusion [GO:0034058]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; organelle fusion [GO:0048284]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein ubiquitination [GO:0016567]; regulation of organelle assembly [GO:1902115]; regulation of protein stability [GO:0031647]; regulation of SNARE complex assembly [GO:0035542]; vacuole organization [GO:0007033]; vesicle docking involved in exocytosis [GO:0006904] autophagosome [GO:0005776]; clathrin-coated vesicle [GO:0030136]; CORVET complex [GO:0033263]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endosome [GO:0005768]; endosome membrane [GO:0010008]; HOPS complex [GO:0030897]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764] metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; protein domain specific binding [GO:0019904]; protein-macromolecule adaptor activity [GO:0030674]; syntaxin binding [GO:0019905]; ubiquitin protein ligase activity [GO:0061630] 0.9655 -2.7202 EKLHAEAISLLKSGR 0 0 11.1981 0 0 0 10.6083 0 0 0 0 11.6541 9.92785 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H299 SH3L3_HUMAN SH3 domain-binding glutamic acid-rich-like protein 3 (SH3 domain-binding protein 1) (SH3BP-1) (TNF inhibitory protein B1) (TIP-B1) SH3BGRL3 P1725 Homo sapiens (Human) cytoskeleton organization [GO:0007010] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; ruffle membrane [GO:0032587] 0.0057143 2.2973 VYSTSVTGSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.28503 0 8.99749 8.70321 8.77017 0 9.39468 9.67237 Q9H2A7 CXL16_HUMAN C-X-C motif chemokine 16 (Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein) (SR-PSOX) (Small-inducible cytokine B16) (Transmembrane chemokine CXCL16) CXCL16 SCYB16 SRPSOX UNQ2759/PRO6714 Homo sapiens (Human) chemotaxis [GO:0006935]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; receptor-mediated endocytosis [GO:0006898]; response to cytokine [GO:0034097]; response to tumor necrosis factor [GO:0034612]; response to type II interferon [GO:0034341]; T cell chemotaxis [GO:0010818] extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886] chemokine activity [GO:0008009]; low-density lipoprotein particle receptor activity [GO:0005041]; scavenger receptor activity [GO:0005044] 0.89857 -0.57627 AYHRCLYYTR 0 0 9.1936 0 0 0 0 0 0 0 10.3662 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H2A9 CHST8_HUMAN Carbohydrate sulfotransferase 8 (EC 2.8.2.-) (GalNAc-4-O-sulfotransferase 1) (GalNAc-4-ST1) (GalNAc4ST-1) (N-acetylgalactosamine-4-O-sulfotransferase 1) CHST8 Homo sapiens (Human) carbohydrate biosynthetic process [GO:0016051]; central nervous system development [GO:0007417]; hormone biosynthetic process [GO:0042446]; proteoglycan biosynthetic process [GO:0030166]; sulfur compound metabolic process [GO:0006790] Golgi membrane [GO:0000139]; membrane [GO:0016020] N-acetylgalactosamine 4-O-sulfotransferase activity [GO:0001537]; sulfotransferase activity [GO:0008146] 0.96114 -2.576 DLSSGAPRGR 0 0 0 0 0 0 0 0 0 9.233 10.332 10.2784 0 12.0056 0 0 0 0 10.3585 9.39474 10.8878 9.59358 10.2596 0 0 0 0 Q9H2B2 SYT4_HUMAN Synaptotagmin-4 (Synaptotagmin IV) (SytIV) SYT4 KIAA1342 Homo sapiens (Human) "calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cell differentiation [GO:0030154]; cellular response to calcium ion [GO:0071277]; dense core granule cytoskeletal transport [GO:0099519]; memory [GO:0007613]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of catecholamine secretion [GO:0033604]; negative regulation of protein secretion [GO:0050709]; negative regulation of retrograde trans-synaptic signaling by neuropeptide [GO:1905433]; negative regulation of short-term neuronal synaptic plasticity [GO:0048174]; negative regulation of synaptic vesicle exocytosis [GO:2000301]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of dendrite extension [GO:1903861]; positive regulation of dense core granule exocytosis [GO:1905415]; positive regulation of glutamate secretion [GO:0014049]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of endocytosis [GO:0030100]; regulation of postsynaptic dense core vesicle exocytosis [GO:0150044]; regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0150035]; regulation of vesicle fusion [GO:0031338]; vesicle fusion [GO:0006906]" astrocyte projection [GO:0097449]; axon [GO:0030424]; dendrite [GO:0030425]; dense core granule membrane [GO:0032127]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; microvesicle [GO:1990742]; neuronal cell body [GO:0043025]; neuronal dense core vesicle [GO:0098992]; neuronal dense core vesicle membrane [GO:0099012]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672] calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; clathrin binding [GO:0030276]; phosphatidylserine binding [GO:0001786]; SNARE binding [GO:0000149] 0.88377 -0.14331 GVDIYPENLNSKK 0 0 0 0 0 0 0 0 0 0 0 0 8.7997 0 0 0 10.6682 0 10.6406 0 0 0 0 0 0 0 0 Q9H2C0 GAN_HUMAN Gigaxonin (Kelch-like protein 16) GAN GAN1 KLHL16 Homo sapiens (Human) cytoskeleton organization [GO:0007010]; protein ubiquitination [GO:0016567] Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829] 0.95045 -1.4089 EQMLNEPLVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.87306 0 0 0 0 0 0 Q9H2C1 LHX5_HUMAN LIM/homeobox protein Lhx5 (LIM homeobox protein 5) LHX5 Homo sapiens (Human) cell proliferation in forebrain [GO:0021846]; cerebellar Purkinje cell differentiation [GO:0021702]; cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation [GO:0021937]; forebrain neuron differentiation [GO:0021879]; hippocampus development [GO:0021766]; neuroblast proliferation [GO:0007405]; neuron differentiation [GO:0030182]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of neuroblast proliferation [GO:1902692]; regulation of transcription by RNA polymerase II [GO:0006357]; spinal cord association neuron differentiation [GO:0021527] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.9511 -1.3838 FLLNVLDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0464 0 Q9H2C8 O51V1_HUMAN Olfactory receptor 51V1 (Odorant receptor HOR3'beta1) (Olfactory receptor 51A12) (Olfactory receptor OR11-36) OR51V1 OR51A12 Homo sapiens (Human) sensory perception of smell [GO:0007608] membrane [GO:0016020]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.95482 -1.52 TQQIHTRMLR 0 0 0 0 0 0 0 0 12.254 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H2D6 TARA_HUMAN TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin) TRIOBP KIAA1662 TARA HRIHFB2122 Homo sapiens (Human) actin modification [GO:0030047]; auditory receptor cell stereocilium organization [GO:0060088]; barbed-end actin filament capping [GO:0051016]; cell cycle [GO:0007049]; cell division [GO:0051301]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; sensory perception of sound [GO:0007605] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; focal adhesion [GO:0005925]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; nucleus [GO:0005634]; stereocilium base [GO:0120044] actin filament binding [GO:0051015]; myosin II binding [GO:0045159]; small GTPase binding [GO:0031267]; ubiquitin protein ligase binding [GO:0031625] 0.96937 -7.3569 ITQRDTSR 0 0 0 0 0 0 0 8.58774 0 0 9.2466 0 9.84123 0 0 9.34917 0 0 0 0 0 0 0 0 0 0 0 Q9H2E6 SEM6A_HUMAN Semaphorin-6A (Semaphorin VIA) (Sema VIA) (Semaphorin-6A-1) (SEMA6A-1) SEMA6A KIAA1368 SEMAQ Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cytoskeleton organization [GO:0007010]; negative chemotaxis [GO:0050919]; negative regulation of angiogenesis [GO:0016525]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion involved in sprouting angiogenesis [GO:0106089]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of sprouting angiogenesis [GO:1903671]; negative regulation of vascular endothelial growth factor signaling pathway [GO:1900747]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; positive regulation of neuron migration [GO:2001224]; semaphorin-plexin signaling pathway [GO:0071526] axon [GO:0030424]; membrane [GO:0016020]; plasma membrane [GO:0005886] chemorepellent activity [GO:0045499]; semaphorin receptor binding [GO:0030215] 0.95993 -1.9688 EASLGPPGASLSQTGLSK 0 9.24389 0 0 9.35903 7.93852 8.76593 9.00773 8.70314 10.4137 10.3669 10.7755 0 0 0 0 0 0 0 0 0 0 0 0 9.28313 0 0 Q9H2F5 EPC1_HUMAN Enhancer of polycomb homolog 1 EPC1 Homo sapiens (Human) "DNA-templated transcription [GO:0006351]; double-strand break repair via homologous recombination [GO:0000724]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of double-strand break repair [GO:2000779]; regulation of transcription by RNA polymerase II [GO:0006357]; sperm DNA condensation [GO:0035092]; spermatid development [GO:0007286]" cytoplasm [GO:0005737]; NuA4 histone acetyltransferase complex [GO:0035267]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; Piccolo NuA4 histone acetyltransferase complex [GO:0032777]; site of double-strand break [GO:0035861] chromatin-protein adaptor activity [GO:0140463]; enzyme-substrate adaptor activity [GO:0140767]; molecular function activator activity [GO:0140677] 0.95094 -1.4356 DLSQILVNIKSCR 0 0 0 0 0 0 0 0 0 0 0 9.62832 0 0 0 0 0 0 0 0 0 10.2004 0 9.2087 0 0 0 Q9H2F9 CCD68_HUMAN Coiled-coil domain-containing protein 68 (Cutaneous T-cell lymphoma-associated antigen se57-1) (CTCL-associated antigen se57-1) CCDC68 Homo sapiens (Human) intracellular signal transduction [GO:0035556]; microtubule anchoring at centrosome [GO:0034454]; protein localization [GO:0008104] centriolar subdistal appendage [GO:0120103]; centriole [GO:0005814]; cytoplasm [GO:0005737] 0.96947 -5.4595 DLQLLEMNK 0 0 0 0 14.6698 0 0 0 9.63499 0 9.05444 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H2G2 SLK_HUMAN STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor antigen se20-9) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (Serine/threonine-protein kinase 2) SLK KIAA0204 STK2 Homo sapiens (Human) apoptotic process [GO:0006915]; cytoplasmic microtubule organization [GO:0031122]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of cell migration [GO:0030334]; regulation of focal adhesion assembly [GO:0051893] cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471] ATP binding [GO:0005524]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96977 -5.3857 AELANIER 9.3468 0 9.17752 0 0 0 0 10.7735 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H2G9 GO45_HUMAN Golgin-45 (Basic leucine zipper nuclear factor 1) (JEM-1) (p45 basic leucine-zipper nuclear factor) BLZF1 JEM1 Homo sapiens (Human) Golgi organization [GO:0007030]; Golgi to plasma membrane protein transport [GO:0043001] cis-Golgi network [GO:0005801]; cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] enzyme binding [GO:0019899]; ubiquitin protein ligase binding [GO:0031625] 0.88651 -0.39058 AAITHDIPNKNTKVK 0 0 0 0 0 0 0 0 0 0 11.0473 0 0 0 11.1648 0 0 8.52572 10.5067 0 0 0 0 0 0 0 12.2495 Q9H2H8 PPIL3_HUMAN Peptidyl-prolyl cis-trans isomerase-like 3 (PPIase) (EC 5.2.1.8) (Cyclophilin J) (CyPJ) (Cyclophilin-like protein PPIL3) (Rotamase PPIL3) PPIL3 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]" catalytic step 2 spliceosome [GO:0071013]; nucleoplasm [GO:0005654] peptidyl-prolyl cis-trans isomerase activity [GO:0003755] 0.88495 -0.29582 IEVFCERTPK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4245 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H2I8 LRMDA_HUMAN Leucine-rich melanocyte differentiation-associated protein LRMDA C10orf11 CDA017 Homo sapiens (Human) melanocyte differentiation [GO:0030318] 0.96283 -2.6668 FIRDDQL 0 10.587 0 0 0 0 0 0 0 9.95369 9.89474 0 0 0 0 0 0 0 0 0 0 0 0 10.1537 0 0 0 Q9H2J7 S6A15_HUMAN Sodium-dependent neutral amino acid transporter B(0)AT2 (Sodium- and chloride-dependent neurotransmitter transporter NTT73) (Sodium-coupled branched-chain amino-acid transporter 1) (Solute carrier family 6 member 15) (Transporter v7-3) SLC6A15 B0AT2 NTT73 SBAT1 Homo sapiens (Human) amino acid transport [GO:0006865]; leucine transport [GO:0015820]; neurotransmitter transport [GO:0006836]; neutral amino acid transport [GO:0015804]; proline transport [GO:0015824]; sodium ion transmembrane transport [GO:0035725] membrane [GO:0016020]; plasma membrane [GO:0005886] amino acid transmembrane transporter activity [GO:0015171]; branched-chain amino acid:sodium symporter activity [GO:0015657]; neurotransmitter transmembrane transporter activity [GO:0005326]; neutral L-amino acid:sodium symporter activity [GO:0005295]; proline:sodium symporter activity [GO:0005298] 0.93976 -1.3238 VVKRELDDDVTESVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2188 0 0 0 0 0 0 0 Q9H2K0 IF3M_HUMAN "Translation initiation factor IF-3, mitochondrial (IF-3(Mt)) (IF-3Mt) (IF3(mt)) (IF3mt)" MTIF3 DC38 Homo sapiens (Human) mitochondrial translational initiation [GO:0070124]; ribosome disassembly [GO:0032790] mitochondrion [GO:0005739] "ribosomal small subunit binding [GO:0043024]; ribosome binding [GO:0043022]; translation factor activity, RNA binding [GO:0008135]; translation initiation factor activity [GO:0003743]" 0.96934 -4.6455 AALFLKRLTLQTVK 0 0 0 0 11.3224 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.14001 9.79549 0 0 0 0 0 Q9H2K8 TAOK3_HUMAN Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) (CTCL-associated antigen HD-CL-09) (Dendritic cell-derived protein kinase) (JNK/SAPK-inhibitory kinase) (Jun kinase-inhibitory kinase) (Kinase from chicken homolog A) (hKFC-A) (Thousand and one amino acid protein 3) TAOK3 DPK JIK KDS MAP3K18 Homo sapiens (Human) DNA damage response [GO:0006974]; DNA repair [GO:0006281]; MAPK cascade [GO:0000165]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of JNK cascade [GO:0046329]; neuron projection morphogenesis [GO:0048812]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of MAPK cascade [GO:0043408] cytoplasm [GO:0005737]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; protein kinase inhibitor activity [GO:0004860]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; transferase activity [GO:0016740] 0.95458 -1.5039 AGNILLTEPGQVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.33958 Q9H2L5 RASF4_HUMAN Ras association domain-containing protein 4 RASSF4 AD037 Homo sapiens (Human) cell cycle [GO:0007049]; signal transduction [GO:0007165] 0.72867 0.33308 ILHGPCEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.77526 0 0 0 0 0 0 0 0 Q9H2M3 BHMT2_HUMAN S-methylmethionine--homocysteine S-methyltransferase BHMT2 (SMM-hcy methyltransferase) (EC 2.1.1.10) (Betaine--homocysteine S-methyltransferase 2) BHMT2 Homo sapiens (Human) L-methionine salvage [GO:0071267]; methylation [GO:0032259]; S-adenosylmethionine metabolic process [GO:0046500]; S-methylmethionine metabolic process [GO:0033477] cytosol [GO:0005829]; extracellular exosome [GO:0070062] S-methylmethionine-homocysteine S-methyltransferase activity [GO:0061627]; zinc ion binding [GO:0008270] 0.96317 -2.1532 GDALVAGGICQTSIYKYQKDEAR 14.8936 0 0 0 0 0 0 0 0 0 0 0 9.68222 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H2M9 RBGPR_HUMAN Rab3 GTPase-activating protein non-catalytic subunit (RGAP-iso) (Rab3 GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP150) (Rab3-GAP regulatory subunit) RAB3GAP2 KIAA0839 Homo sapiens (Human) establishment of protein localization to endoplasmic reticulum membrane [GO:0097051]; intracellular protein transport [GO:0006886]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of endoplasmic reticulum tubular network organization [GO:1903373]; positive regulation of protein lipidation [GO:1903061]; regulation of GTPase activity [GO:0043087] cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] enzyme activator activity [GO:0008047]; enzyme regulator activity [GO:0030234]; GTPase activator activity [GO:0005096]; small GTPase binding [GO:0031267] 0.96054 -1.9932 DMHLVKKLAALLK 0 8.86882 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H2S5 RNF39_HUMAN RING finger protein 39 (Protein HZFw) RNF39 HZFW Homo sapiens (Human) protein ubiquitination [GO:0016567] cytoplasm [GO:0005737] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630] 0.92213 -1.1243 GIYTASSRGGPPSAR 0 0 0 0 0 0 0 0 0 9.97528 0 0 0 0 0 0 0 0 0 0 0 8.86484 0 0 0 0 0 Q9H2S6 TNMD_HUMAN Tenomodulin (TeM) (hTeM) (Chondromodulin-1-like protein) (ChM1L) (hChM1L) (Chondromodulin-I-like protein) (Myodulin) (Tendin) TNMD CHM1L UNQ771/PRO1565 Homo sapiens (Human) endothelial cell morphogenesis [GO:0001886]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937] cytoplasm [GO:0005737]; membrane [GO:0016020]; nuclear envelope [GO:0005635] 0.88351 -0.12408 VIMPCNWWVARMLGRV 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2299 0 0 Q9H2S9 IKZF4_HUMAN Zinc finger protein Eos (Ikaros family zinc finger protein 4) IKZF4 KIAA1782 ZNFN1A4 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein homooligomerization [GO:0051260]; regulation of transcription by RNA polymerase II [GO:0006357] nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] bHLH transcription factor binding [GO:0043425]; DNA-binding transcription factor activity [GO:0003700]; protein domain specific binding [GO:0019904]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; zinc ion binding [GO:0008270] 0.33883 0.77144 GTPGPSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.31447 0 0 0 0 0 0 0 0 0 Q9H2T7 RBP17_HUMAN Ran-binding protein 17 RANBP17 Homo sapiens (Human) mRNA transport [GO:0051028]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606] cytoplasm [GO:0005737]; nuclear pore [GO:0005643] GTP binding [GO:0005525]; nuclear export signal receptor activity [GO:0005049]; small GTPase binding [GO:0031267] 0.72778 0.34451 ASLINSQPLPK 0 0 0 0 0 0 0 0 0 0 0 11.5571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H2U1 DHX36_HUMAN ATP-dependent DNA/RNA helicase DHX36 (EC 3.6.4.12) (EC 3.6.4.13) (DEAD/H box polypeptide 36) (DEAH-box protein 36) (G4-resolvase-1) (G4R1) (MLE-like protein 1) (RNA helicase associated with AU-rich element protein) DHX36 DDX36 KIAA1488 MLEL1 RHAU Homo sapiens (Human) "3'-UTR-mediated mRNA destabilization [GO:0061158]; cell differentiation [GO:0030154]; cellular response to arsenite ion [GO:1903843]; cellular response to heat [GO:0034605]; cellular response to UV [GO:0034644]; defense response to virus [GO:0051607]; G-quadruplex DNA unwinding [GO:0044806]; innate immune response [GO:0045087]; negative regulation of translation [GO:0017148]; ossification [GO:0001503]; positive regulation of cardioblast differentiation [GO:0051891]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of gene expression [GO:0010628]; positive regulation of hematopoietic progenitor cell differentiation [GO:1901534]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of intracellular mRNA localization [GO:1904582]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of myeloid dendritic cell cytokine production [GO:0002735]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of telomere maintenance [GO:0032206]; positive regulation of telomere maintenance via telomere lengthening [GO:1904358]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; regulation of embryonic development [GO:0045995]; regulation of mRNA stability [GO:0043488]; regulation of transcription by RNA polymerase III [GO:0006359]; response to exogenous dsRNA [GO:0043330]; RNA secondary structure unwinding [GO:0010501]; spermatogenesis [GO:0007283]; telomerase RNA stabilization [GO:0090669]" "axon [GO:0030424]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]" "ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent activity, acting on DNA [GO:0008094]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; G-quadruplex DNA binding [GO:0051880]; G-quadruplex RNA binding [GO:0002151]; histone deacetylase binding [GO:0042826]; magnesium ion binding [GO:0000287]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA 5'-UTR binding [GO:0048027]; pre-miRNA binding [GO:0070883]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; single-stranded DNA binding [GO:0003697]; telomerase RNA binding [GO:0070034]; transcription cis-regulatory region binding [GO:0000976]" 0.96952 -3.0493 DPFVIPLGKEKIADAR 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5381 0 0 8.05273 0 0 0 0 0 0 0 0 0 0 Q9H2U2 IPYR2_HUMAN "Inorganic pyrophosphatase 2, mitochondrial (EC 3.6.1.1) (Pyrophosphatase SID6-306) (Pyrophosphate phospho-hydrolase 2) (PPase 2)" PPA2 HSPC124 Homo sapiens (Human) diphosphate metabolic process [GO:0071344]; phosphate-containing compound metabolic process [GO:0006796]; regulation of mitochondrial membrane potential [GO:0051881] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; synapse [GO:0045202] inorganic diphosphate phosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; protein serine/threonine phosphatase activity [GO:0004722] 0.82083 0.21694 TGAPAAACLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.89341 0 0 0 Q9H2U9 ADAM7_HUMAN Disintegrin and metalloproteinase domain-containing protein 7 (ADAM 7) (Sperm maturation-related glycoprotein GP-83) ADAM7 GP83 Homo sapiens (Human) proteolysis [GO:0006508] plasma membrane [GO:0005886] metalloendopeptidase activity [GO:0004222] 0.95915 -1.8376 FLPCEEKDVR 0 0 0 11.4048 0 0 0 11.6781 11.6719 10.4525 11.4192 0 0 0 0 0 0 0 0 0 10.0968 0 0 0 0 0 0 Q9H2W6 RM46_HUMAN "Large ribosomal subunit protein mL46 (39S ribosomal protein L46, mitochondrial) (L46mt) (MRP-L46) (P2ECSL)" MRPL46 C15orf4 LIECG2 Homo sapiens (Human) mitochondrial translation [GO:0032543] cell junction [GO:0030054]; mitochondrial inner membrane [GO:0005743]; mitochondrial large ribosomal subunit [GO:0005762]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] structural constituent of ribosome [GO:0003735] 0.9638 -2.1121 ALDENQRLAK 0 0 9.39934 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2864 0 Q9H2X0 CHRD_HUMAN Chordin CHRD UNQ217/PRO243 Homo sapiens (Human) BMP signaling pathway involved in spinal cord dorsal/ventral patterning [GO:0021919]; dorsal/ventral pattern formation [GO:0009953]; floor plate development [GO:0033504]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell migration [GO:0030336]; negative regulation of osteoblast differentiation [GO:0045668]; positive regulation of cell adhesion [GO:0045785]; positive regulation of mesenchymal cell proliferation [GO:0002053]; skeletal system development [GO:0001501] extracellular space [GO:0005615] BMP binding [GO:0036122]; cytokine binding [GO:0019955] 0.88314 -0.29928 DPEHRSYSDR 0 0 8.49813 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H2X9 S12A5_HUMAN Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (hKCC2) (Neuronal K-Cl cotransporter) SLC12A5 KCC2 KIAA1176 Homo sapiens (Human) cell volume homeostasis [GO:0006884]; chemical synaptic transmission [GO:0007268]; chloride ion homeostasis [GO:0055064]; chloride transmembrane transport [GO:1902476]; dendritic spine development [GO:0060996]; hypotonic response [GO:0006971]; intracellular chloride ion homeostasis [GO:0030644]; intracellular pH reduction [GO:0051452]; learning [GO:0007612]; monoatomic ion transport [GO:0006811]; multicellular organism growth [GO:0035264]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; response to xenobiotic stimulus [GO:0009410]; thermosensory behavior [GO:0040040] cell periphery [GO:0071944]; dendrite membrane [GO:0032590]; membrane [GO:0016020]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; synapse [GO:0045202] ammonium transmembrane transporter activity [GO:0008519]; chloride transmembrane transporter activity [GO:0015108]; potassium:chloride symporter activity [GO:0015379]; protein kinase binding [GO:0019901] 0.74721 0.31506 ENLWSSYLTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.8706 0 0 0 0 Q9H2Y7 ZN106_HUMAN Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) ZNF106 SH3BP3 ZFP106 ZNF474 Homo sapiens (Human) insulin receptor signaling pathway [GO:0008286] cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730] metal ion binding [GO:0046872]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124] 0.96948 -5.0819 AGQSQKATMHLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.38143 0 0 0 0 0 0 0 Q9H300 PARL_HUMAN "Presenilin-associated rhomboid-like protein, mitochondrial (EC 3.4.21.105) (Mitochondrial intramembrane cleaving protease PARL) [Cleaved into: P-beta (Pbeta)]" PARL PSARL PRO2207 Homo sapiens (Human) membrane protein proteolysis [GO:0033619]; mitochondrial fusion [GO:0008053]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of mitochondrion organization [GO:0010821]; regulation of protein targeting to mitochondrion [GO:1903214]; regulation of proteolysis [GO:0030162]; regulation of reactive oxygen species metabolic process [GO:2000377]; signal peptide processing [GO:0006465] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; nucleus [GO:0005634] endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252] 0.95217 -1.4781 VPSLQRTMIR 0 0 10.0712 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H305 CDIP1_HUMAN Cell death-inducing p53-target protein 1 (Cell death involved p53-target) (Cell death-inducing protein) (LITAF-like protein) (Lipopolysaccharide-induced tumor necrosis factor-alpha-like protein) (Transmembrane protein I1) CDIP1 C16orf5 CDIP LITAFL Homo sapiens (Human) intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771] cytoplasmic side of late endosome membrane [GO:0098560]; cytoplasmic side of lysosomal membrane [GO:0098574]; nucleus [GO:0005634] zinc ion binding [GO:0008270] 0.84795 0.15775 AYIYTYK 0 0 8.66761 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H306 MMP27_HUMAN Matrix metalloproteinase-27 (MMP-27) (EC 3.4.24.-) MMP27 UNQ2503/PRO5992 Homo sapiens (Human) collagen catabolic process [GO:0030574]; extracellular matrix organization [GO:0030198]; proteolysis [GO:0006508] extracellular matrix [GO:0031012]; extrinsic component of endoplasmic reticulum membrane [GO:0042406] metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270] 0.96392 -2.1045 EVMFFKGR 0 0 0 0 0 0 10.1128 0 11.5779 10.935 0 0 0 0 8.87458 8.87646 0 0 0 0 0 0 0 0 0 0 0 Q9H307 PININ_HUMAN Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Desmosome-associated protein) (Domain-rich serine protein) (DRS protein) (DRSP) (Melanoma metastasis clone A protein) (Nuclear protein SDK3) (SR-like protein) PNN DRS MEMA Homo sapiens (Human) "cell adhesion [GO:0007155]; mRNA splicing, via spliceosome [GO:0000398]" catalytic step 2 spliceosome [GO:0071013]; cell-cell junction [GO:0005911]; desmosome [GO:0030057]; intermediate filament [GO:0005882]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] DNA binding [GO:0003677]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198] 0.96206 -2.4643 ELFEERRAK 0 0 0 0 0 0 0 0 11.7619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2596 Q9H329 E41LB_HUMAN Band 4.1-like protein 4B (Erythrocyte membrane protein band 4.1-like 4B) (FERM-containing protein CG1) (Protein EHM2) EPB41L4B EHM2 LULU2 Homo sapiens (Human) actomyosin structure organization [GO:0031032]; positive regulation of cell adhesion [GO:0045785]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte migration [GO:0051549]; wound healing [GO:0042060] apical part of cell [GO:0045177]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; plasma membrane [GO:0005886] cytoskeletal protein binding [GO:0008092]; structural constituent of cytoskeleton [GO:0005200] 0.8828 -0.093733 AKWLEMYGVDMHVVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.309 0 8.83986 Q9H330 TM245_HUMAN Transmembrane protein 245 (Protein CG-2) TMEM245 C9orf5 Homo sapiens (Human) membrane [GO:0016020] 0.4602 0.63824 ADGGGPK 0 0 0 0 0 0 0 0 0 10.5771 0 7.74025 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5738 0 Q9H346 O52D1_HUMAN Olfactory receptor 52D1 (Odorant receptor HOR5'beta14) (Olfactory receptor OR11-43) OR52D1 Homo sapiens (Human) sensory perception of smell [GO:0007608] membrane [GO:0016020]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.91328 -0.78613 FGHHEVPK 0 0 0 0 7.85742 0 9.35423 9.33689 0 9.34789 0 0 0 9.13042 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H354 YJ001_HUMAN Putative uncharacterized protein PRO1933 PRO1933 Homo sapiens (Human) membrane [GO:0016020] 0.93259 -1.2761 EKIPPNHR 11.9282 0 0 0 0 0 11.5035 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H3E2 SNX25_HUMAN Sorting nexin-25 SNX25 MSTP043 Homo sapiens (Human) negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; protein transport [GO:0015031]; receptor catabolic process [GO:0032801] endosome [GO:0005768]; endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231] phosphatidylinositol binding [GO:0035091] 0.88475 -0.22056 DRYYPSFIVSDLYEK 11.3504 0 0 0 0 9.26132 0 0 0 9.05861 0 10.3742 0 0 0 0 0 0 0 9.78337 0 0 10.9006 0 0 0 0 Q9H3G5 CPVL_HUMAN "Probable serine carboxypeptidase CPVL (EC 3.4.16.-) (Carboxypeptidase, vitellogenic-like) (Vitellogenic carboxypeptidase-like protein) (VCP-like protein) (hVLP)" CPVL VLP PSEC0124 UNQ197/PRO223 Homo sapiens (Human) proteolysis [GO:0006508] extracellular exosome [GO:0070062] serine-type carboxypeptidase activity [GO:0004185] 0.76923 0.26878 QAGDFHQVIIR 0 0 10.0003 0 0 0 0 8.81215 0 0 9.56744 9.66297 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H3H3 CK068_HUMAN UPF0696 protein C11orf68 (Basophilic leukemia-expressed protein Bles03) (Protein p5326) C11orf68 BLES03 Homo sapiens (Human) RNA binding [GO:0003723] 0.94639 -1.3458 GWAGVER 0 0 0 0 0 0 0 11.2913 0 0 11.149 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H3K6 BOLA2_HUMAN BolA-like protein 2 BOLA2 BOLA2A My016; BOLA2B Homo sapiens (Human) [2Fe-2S] cluster assembly [GO:0044571]; cell redox homeostasis [GO:0045454]; intracellular iron ion homeostasis [GO:0006879]; iron-sulfur cluster assembly [GO:0016226]; protein maturation by iron-sulfur cluster transfer [GO:0097428] cytoplasm [GO:0005737]; cytosol [GO:0005829]; iron-sulfur cluster assembly complex [GO:1990229]; nucleus [GO:0005634] "2 iron, 2 sulfur cluster binding [GO:0051537]; iron-sulfur cluster binding [GO:0051536]" 0.56359 0.49003 TLTPDQWAR 0 0 0 0 0 0 0 0 0 0 0 9.71691 0 0 0 0 0 0 0 0 0 0 9.53902 0 0 0 0 Q9H3M0 KCNF1_HUMAN Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1) KCNF1 Homo sapiens (Human) non-motile cilium assembly [GO:1905515]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of monoatomic ion transmembrane transport [GO:0034765] ciliary base [GO:0097546]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076] potassium channel activity [GO:0005267]; voltage-gated potassium channel activity [GO:0005249] 0.91612 -0.7686 RCQKCVWK 9.10944 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H3P2 NELFA_HUMAN Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein) NELFA WHSC2 P/OKcl.15 Homo sapiens (Human) negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of transcription by RNA polymerase II [GO:0045944] cytosol [GO:0005829]; NELF complex [GO:0032021]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; molecular adaptor activity [GO:0060090] 0.95965 -1.8588 GIPKQAPFR 0 0 0 0 0 0 0 9.80402 0 0 0 0 0 0 0 0 0 0 9.1982 0 0 0 0 0 0 0 0 Q9H3P7 GCP60_HUMAN "Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi complex-associated protein 1) (GOCAP1) (Golgi phosphoprotein 1) (GOLPH1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7) [Cleaved into: Golgi resident protein GCP60, N-terminally processed]" ACBD3 GCP60 GOCAP1 GOLPH1 Homo sapiens (Human) steroid biosynthetic process [GO:0006694] Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; mitochondrion [GO:0005739] fatty-acyl-CoA binding [GO:0000062]; protein kinase A regulatory subunit binding [GO:0034237] 0.87527 0.0009225 EDAMVEFVK 0 0 0 0 0 0 0 0 0 0 8.83343 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H3R0 KDM4C_HUMAN Lysine-specific demethylase 4C (EC 1.14.11.66) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein) (JmjC domain-containing histone demethylation protein 3C) (Jumonji domain-containing protein 2C) ([histone H3]-trimethyl-L-lysine(9) demethylase 4C) KDM4C GASC1 JHDM3C JMJD2C KIAA0780 Homo sapiens (Human) blastocyst formation [GO:0001825]; chromatin remodeling [GO:0006338]; histone H3-K9 demethylation [GO:0033169]; positive regulation of cell population proliferation [GO:0008284]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of stem cell differentiation [GO:2000736]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721] enzyme binding [GO:0019899]; histone demethylase activity [GO:0032452]; histone H3K36 demethylase activity [GO:0051864]; histone H3K9 demethylase activity [GO:0032454]; histone H3K9me2/H3K9me3 demethylase activity [GO:0140684]; nuclear androgen receptor binding [GO:0050681]; zinc ion binding [GO:0008270] 0.95316 -1.4796 RNAWTAECCLCNLRGGALK 0 0 0 0 0 0 0 0 0 0 0 0 10.0239 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H3R1 NDST4_HUMAN Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST-4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 4 (EC 2.8.2.-)] NDST4 HSST4 Homo sapiens (Human) "heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; heparin biosynthetic process [GO:0030210]" Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139] [heparan sulfate]-glucosamine N-sulfotransferase activity [GO:0015016]; deacetylase activity [GO:0019213]; N-acetylglucosamine deacetylase activity [GO:0050119] 0.95504 -1.556 DIWSREK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.73679 0 0 0 Q9H3S1 SEM4A_HUMAN Semaphorin-4A (Semaphorin-B) (Sema B) SEMA4A SEMAB SEMB UNQ783/PRO1317 Homo sapiens (Human) angiogenesis [GO:0001525]; axonogenesis [GO:0007409]; negative chemotaxis [GO:0050919]; negative regulation of angiogenesis [GO:0016525]; negative regulation of axon extension involved in axon guidance [GO:0048843]; neural crest cell migration [GO:0001755]; positive regulation of cell migration [GO:0030335]; positive regulation of excitatory synapse assembly [GO:1904891]; positive regulation of inhibitory synapse assembly [GO:1905704]; regulation of cell shape [GO:0008360]; regulation of endothelial cell migration [GO:0010594]; semaphorin-plexin signaling pathway [GO:0071526]; T-helper 1 cell differentiation [GO:0045063] plasma membrane [GO:0005886] chemorepellent activity [GO:0045499]; semaphorin receptor binding [GO:0030215] 0.92412 -1.0689 GLQDFDTLLLSGDGNTLYVGAR 8.54782 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.82343 0 0 0 Q9H3S3 TMPS5_HUMAN Transmembrane protease serine 5 (EC 3.4.21.-) (Spinesin) TMPRSS5 Homo sapiens (Human) proteolysis [GO:0006508] neuronal cell body [GO:0043025]; plasma membrane [GO:0005886] peptidase activity [GO:0008233]; scavenger receptor activity [GO:0005044]; serine-type endopeptidase activity [GO:0004252] 0.88618 -0.33656 EQHFPKGSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.603 0 0 0 0 0 0 0 Q9H3S7 PTN23_HUMAN Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14) PTPN23 KIAA1471 Homo sapiens (Human) cilium assembly [GO:0060271]; early endosome to late endosome transport [GO:0045022]; endocytic recycling [GO:0032456]; negative regulation of epithelial cell migration [GO:0010633]; positive regulation of adherens junction organization [GO:1903393]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of homophilic cell adhesion [GO:1903387]; positive regulation of Wnt protein secretion [GO:0061357]; protein dephosphorylation [GO:0006470]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725] 0.92435 -1.0016 KLELLRQNAVR 0 0 0 0 0 0 0 0 0 0 0 0 9.25311 0 0 0 0 0 0 10.2037 0 11.0877 0 10.24 0 0 12.3246 Q9H3T2 SEM6C_HUMAN Semaphorin-6C (Semaphorin-Y) (Sema Y) SEMA6C KIAA1869 SEMAY Homo sapiens (Human) axon guidance [GO:0007411]; negative chemotaxis [GO:0050919]; negative regulation of axon extension [GO:0030517]; negative regulation of axon extension involved in axon guidance [GO:0048843]; neural crest cell migration [GO:0001755]; positive regulation of cell migration [GO:0030335]; semaphorin-plexin signaling pathway [GO:0071526] cell surface [GO:0009986]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886] chemorepellent activity [GO:0045499]; semaphorin receptor binding [GO:0030215] 0.95988 -1.9374 LGVGGGRR 0 9.96939 0 0 0 0 0 0 0 0 0 0 9.36988 0 0 0 0 0 0 0 0 0 0 0 11.6567 0 0 Q9H3U1 UN45A_HUMAN Protein unc-45 homolog A (Unc-45A) (GCUNC-45) (Smooth muscle cell-associated protein 1) (SMAP-1) UNC45A SMAP1 Homo sapiens (Human) cell differentiation [GO:0030154]; chaperone-mediated protein folding [GO:0061077]; muscle organ development [GO:0007517] cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nuclear speck [GO:0016607]; perinuclear region of cytoplasm [GO:0048471] cadherin binding [GO:0045296]; Hsp90 protein binding [GO:0051879] 0.20368 0.91549 AAAACLDK 0 11.7062 0 0 0 11.6201 11.2664 0 11.6695 10.9388 0 10.5014 0 0 0 0 0 0 0 0 0 12.0153 11.9996 0 0 0 13.1634 Q9H3U7 SMOC2_HUMAN SPARC-related modular calcium-binding protein 2 (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2) SMOC2 SMAP2 MSTP117 Homo sapiens (Human) extracellular matrix organization [GO:0030198]; positive regulation of angiogenesis [GO:0045766]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; positive regulation of vascular wound healing [GO:0035470] basement membrane [GO:0005604]; cell periphery [GO:0071944]; extracellular space [GO:0005615] calcium ion binding [GO:0005509]; extracellular matrix binding [GO:0050840]; heparin binding [GO:0008201] 0.88974 -0.42248 DVSRCVAERK 0 0 0 0 0 0 0 0 0 0 11.3112 0 0 0 0 9.44603 0 0 0 0 0 0 0 0 0 0 0 Q9H3W5 LRRN3_HUMAN Leucine-rich repeat neuronal protein 3 (Neuronal leucine-rich repeat protein 3) (NLRR-3) LRRN3 Nbla10363 UNQ194/PRO220 Homo sapiens (Human) positive regulation of synapse assembly [GO:0051965] extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; membrane [GO:0016020] 0.90607 -0.71277 FYVHSEGTLDINGVTPK 0 0 0 0 0 10.3821 0 0 0 10.7283 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H3Y6 SRMS_HUMAN Tyrosine-protein kinase Srms (EC 2.7.10.2) SRMS C20orf148 Homo sapiens (Human) cell differentiation [GO:0030154]; innate immune response [GO:0045087]; negative regulation of signal transduction [GO:0009968]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234] ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102] 0.94124 -1.3139 GLRHERLIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0865 0 0 0 0 0 0 Q9H3Z7 ABHGB_HUMAN Protein ABHD16B (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 16B) (Abhydrolase domain-containing protein 16B) ABHD16B C20orf135 Homo sapiens (Human) monoacylglycerol catabolic process [GO:0052651]; phosphatidylserine catabolic process [GO:0006660] nucleoplasm [GO:0005654] acylglycerol lipase activity [GO:0047372]; phospholipase activity [GO:0004620] 0.19784 0.92438 GWPVAFRWDDVR 11.8312 11.6839 0 10.582 10.8325 10.6986 13.1014 11.7773 11.3826 11.9857 11.6001 12.202 10.8078 10.9086 0 0 11.616 11.3371 0 0 0 0 0 0 0 0 0 Q9H425 CA198_HUMAN Uncharacterized protein C1orf198 C1orf198 Homo sapiens (Human) cytosol [GO:0005829] 0.89889 -0.58982 KIMQDKEK 0 0 0 0 8.05246 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H461 FZD8_HUMAN Frizzled-8 (Fz-8) (hFz8) FZD8 Homo sapiens (Human) angiogenesis [GO:0001525]; canonical Wnt signaling pathway [GO:0060070]; neuron differentiation [GO:0030182]; non-canonical Wnt signaling pathway [GO:0035567]; positive regulation of JUN kinase activity [GO:0043507]; T cell differentiation in thymus [GO:0033077] Golgi apparatus [GO:0005794]; membrane [GO:0016020]; neuronal dense core vesicle [GO:0098992]; plasma membrane [GO:0005886]; Wnt-Frizzled-LRP5/6 complex [GO:1990851] G protein-coupled receptor activity [GO:0004930]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; Wnt receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147] 0.65065 0.39598 GGGGGGK 0 0 7.46123 0 0 0 10.1001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H488 OFUT1_HUMAN GDP-fucose protein O-fucosyltransferase 1 (EC 2.4.1.221) (Peptide-O-fucosyltransferase 1) (O-FucT-1) POFUT1 FUT12 KIAA0180 Homo sapiens (Human) angiogenesis [GO:0001525]; fucose metabolic process [GO:0006004]; heart development [GO:0007507]; nervous system development [GO:0007399]; Notch signaling pathway [GO:0007219]; O-glycan processing [GO:0016266]; protein O-linked fucosylation [GO:0036066]; protein O-linked glycosylation [GO:0006493]; regulation of DNA-templated transcription [GO:0006355]; regulation of Notch signaling pathway [GO:0008593]; somitogenesis [GO:0001756] endoplasmic reticulum [GO:0005783]; membrane [GO:0016020] fucosyltransferase activity [GO:0008417]; peptide-O-fucosyltransferase activity [GO:0046922] 0.92623 -1.2082 EQWSQRFSPK 0 0 0 0 0 9.2863 0 9.8518 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H489 TSY26_HUMAN Putative testis-specific Y-encoded-like protein 3 (TSPY-like protein 3) (Testis-specific Y-encoded protein 26 pseudogene) TSPY26P TSPYL3 Homo sapiens (Human) nucleosome assembly [GO:0006334] chromatin [GO:0000785]; nucleus [GO:0005634] chromatin binding [GO:0003682]; histone binding [GO:0042393] 0.92773 -1.2225 VIVKEYECR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8584 0 0 0 0 0 0 0 0 Q9H497 TOR3A_HUMAN Torsin-3A (ATP-dependent interferon-responsive protein) (Torsin family 3 member A) TOR3A ADIR Homo sapiens (Human) endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; nuclear envelope [GO:0005635] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887] 0.96873 -3.9114 AAGALSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2062 0 0 0 0 0 0 0 0 0 0 0 Q9H4A3 WNK1_HUMAN Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Erythrocyte 65 kDa protein) (p65) (Kinase deficient protein) (Protein kinase lysine-deficient 1) (Protein kinase with no lysine 1) (hWNK1) WNK1 HSN2 KDP KIAA0344 PRKWNK1 Homo sapiens (Human) cellular response to chemokine [GO:1990869]; chemokine (C-C motif) ligand 21 signaling pathway [GO:0038116]; intracellular chloride ion homeostasis [GO:0030644]; intracellular signal transduction [GO:0035556]; lymphocyte migration into lymph node [GO:0097022]; monoatomic cation homeostasis [GO:0055080]; monoatomic ion transport [GO:0006811]; negative regulation of cell-cell adhesion mediated by integrin [GO:0033633]; negative regulation of GTPase activity [GO:0034260]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of leukocyte cell-cell adhesion [GO:1903038]; negative regulation of pancreatic juice secretion [GO:0090188]; negative regulation of sodium ion transport [GO:0010766]; neuron development [GO:0048666]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of systemic arterial blood pressure [GO:0003084]; positive regulation of T cell chemotaxis [GO:0010820]; potassium ion homeostasis [GO:0055075]; protein phosphorylation [GO:0006468]; regulation of monoatomic cation transmembrane transport [GO:1904062]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of sodium ion transport [GO:0002028]; signal transduction [GO:0007165]; sodium ion transmembrane transport [GO:0035725]; T cell receptor signaling pathway [GO:0050852] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; protein-containing complex [GO:0032991] ATP binding [GO:0005524]; chloride channel inhibitor activity [GO:0019869]; phosphatase binding [GO:0019902]; protein kinase activator activity [GO:0030295]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein kinase inhibitor activity [GO:0004860]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.9642 -2.2622 AIKDRVSLIK 9.25165 9.38334 10.234 0 0 12.8109 9.04037 9.13881 14.2698 0 0 13.9599 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4969 0 Q9H4A4 AMPB_HUMAN Aminopeptidase B (AP-B) (EC 3.4.11.6) (Arginine aminopeptidase) (Arginyl aminopeptidase) RNPEP APB Homo sapiens (Human) proteolysis [GO:0006508] extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; metalloaminopeptidase activity [GO:0070006]; metalloexopeptidase activity [GO:0008235]; zinc ion binding [GO:0008270] 0.020501 1.6078 AEFGPPGPGAGSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.8373 0 0 0 10.9889 10.6646 10.2557 Q9H4A6 GOLP3_HUMAN Golgi phosphoprotein 3 (Coat protein GPP34) (Mitochondrial DNA absence factor) (MIDAS) GOLPH3 GPP34 Homo sapiens (Human) "asymmetric Golgi ribbon formation [GO:0090164]; cell adhesion molecule production [GO:0060352]; cell migration [GO:0016477]; cellular response to rapamycin [GO:0072752]; gene expression [GO:0010467]; glycoprotein biosynthetic process [GO:0009101]; Golgi organization [GO:0007030]; Golgi ribbon formation [GO:0090161]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi vesicle budding [GO:0048194]; lamellipodium assembly [GO:0030032]; leukocyte tethering or rolling [GO:0050901]; negative regulation of apoptotic process [GO:0043066]; positive regulation of protein secretion [GO:0050714]; positive regulation of TOR signaling [GO:0032008]; protein retention in Golgi apparatus [GO:0045053]; protein secretion [GO:0009306]; regulation of mitochondrion organization [GO:0010821]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]" cytosol [GO:0005829]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802] enzyme binding [GO:0019899]; phosphatidylinositol-4-phosphate binding [GO:0070273] 0.96292 -2.1238 AAGGGAGSSEDDAQSRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.13052 0 0 0 0 0 Q9H4A9 DPEP2_HUMAN Dipeptidase 2 (EC 3.4.13.19) DPEP2 UNQ284/PRO323 Homo sapiens (Human) leukotriene D4 catabolic process [GO:1901749]; leukotriene metabolic process [GO:0006691]; proteolysis [GO:0006508] membrane [GO:0016020] dipeptidase activity [GO:0016805]; metal ion binding [GO:0046872]; metallodipeptidase activity [GO:0070573] 0.85802 0.10031 VQEENKWQSPLEDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.16279 0 0 0 0 0 0 0 0 0 0 Q9H4B6 SAV1_HUMAN Protein salvador homolog 1 (45 kDa WW domain protein) (hWW45) SAV1 WW45 Homo sapiens (Human) cardiac muscle cell proliferation [GO:0060038]; epithelial cell proliferation [GO:0050673]; hair follicle development [GO:0001942]; hippo signaling [GO:0035329]; intestinal epithelial cell differentiation [GO:0060575]; keratinocyte apoptotic process [GO:0097283]; keratinocyte differentiation [GO:0030216]; lung epithelial cell differentiation [GO:0060487]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epithelial cell proliferation [GO:0050680]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of keratinocyte apoptotic process [GO:1902174]; protein stabilization [GO:0050821]; regulation of stem cell population maintenance [GO:2000036]; ventricular septum morphogenesis [GO:0060412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] identical protein binding [GO:0042802]; molecular adaptor activity [GO:0060090] 0.42287 0.66841 EGLPPGWER 0 0 0 0 0 0 0 0 0 0 0 10.0689 0 0 0 0 0 0 0 10.0371 0 0 0 0 0 0 0 Q9H4B7 TBB1_HUMAN Tubulin beta-1 chain TUBB1 Homo sapiens (Human) microtubule cytoskeleton organization [GO:0000226]; microtubule polymerization [GO:0046785]; mitotic cell cycle [GO:0000278]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; spindle assembly [GO:0051225]; thyroid gland development [GO:0030878]; thyroid hormone transport [GO:0070327] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; mitotic spindle [GO:0072686] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; structural constituent of cytoskeleton [GO:0005200] 0.92777 -1.1999 FPGQLNADLR 0 0 0 0 0 0 0 0 0 0 0 11.1317 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H4D0 CSTN2_HUMAN Calsyntenin-2 (Alcadein-gamma) (Alc-gamma) CLSTN2 CS2 Homo sapiens (Human) associative learning [GO:0008306]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inhibitory synapse assembly [GO:1904862]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission [GO:0050806] cell surface [GO:0009986]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211] amyloid-beta binding [GO:0001540]; calcium ion binding [GO:0005509]; kinesin binding [GO:0019894]; X11-like protein binding [GO:0042988] 0.1634 0.98352 DAPVPFAGEICAFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7447 10.9302 11.0701 0 10.4527 0 10.5054 0 0 10.1311 11.2785 11.0847 10.9593 Q9H4D5 NXF3_HUMAN Nuclear RNA export factor 3 (TAP-like protein 3) (TAPL-3) NXF3 TAPL3 Homo sapiens (Human) mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973] cytoplasm [GO:0005737]; nuclear RNA export factor complex [GO:0042272]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] RNA binding [GO:0003723] 0.96846 -2.7691 ILKDPYLR 0 0 0 0 0 0 0 0 0 0 0 10.8512 14.4107 0 0 0 0 0 0 10.1068 0 0 0 0 0 0 0 Q9H4E5 RHOJ_HUMAN Rho-related GTP-binding protein RhoJ (Ras-like protein family member 7B) (Tc10-like GTP-binding protein) RHOJ ARHJ RASL7B RHOI TCL Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; angiogenesis [GO:0001525]; Cdc42 protein signal transduction [GO:0032488]; endocytosis [GO:0006897]; establishment or maintenance of cell polarity [GO:0007163]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; regulation of cell shape [GO:0008360]; regulation of endothelial cell migration [GO:0010594]; regulation of sprouting angiogenesis [GO:1903670]; retina vasculature morphogenesis in camera-type eye [GO:0061299] extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.91508 -0.7808 LLYMKEKPLTYEHGVK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.42074 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H4E7 DEFI6_HUMAN Differentially expressed in FDCP 6 homolog (DEF-6) (IRF4-binding protein) DEF6 IBP Homo sapiens (Human) regulation of small GTPase mediated signal transduction [GO:0051056]; vesicle-mediated transport to the plasma membrane [GO:0098876] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; filopodium [GO:0030175]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] guanyl-nucleotide exchange factor activity [GO:0005085] 0.96744 -2.337 ADEDVEAAQRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2099 0 0 0 Q9H4F1 SIA7D_HUMAN "Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase (EC 2.4.3.7) (NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase) (ST6GalNAc IV) (ST6GalNAcIV) (Sialyltransferase 3C) (SIAT3-C) (Sialyltransferase 7D) (SIAT7-D)" ST6GALNAC4 SIAT3C SIAT7D Homo sapiens (Human) ganglioside biosynthetic process [GO:0001574]; glycolipid metabolic process [GO:0006664]; O-glycan processing [GO:0016266]; oligosaccharide metabolic process [GO:0009311]; viral protein processing [GO:0019082] Golgi membrane [GO:0000139] "(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity [GO:0047290]; alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity [GO:0001665]; sialyltransferase activity [GO:0008373]" 0.95518 -1.5211 HMDRVLGGR 0 0 0 0 11.6247 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H4F8 SMOC1_HUMAN SPARC-related modular calcium-binding protein 1 (Secreted modular calcium-binding protein 1) (SMOC-1) SMOC1 Homo sapiens (Human) cell differentiation [GO:0030154]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; limb development [GO:0060173]; regulation of osteoblast differentiation [GO:0045667] basement membrane [GO:0005604]; extracellular space [GO:0005615] calcium ion binding [GO:0005509]; extracellular matrix binding [GO:0050840]; heparin binding [GO:0008201] 0.91757 -0.85328 VYSCDQERQSALEEAQQNPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.51377 0 0 0 0 0 0 0 0 Q9H4H8 FA83D_HUMAN Protein FAM83D (Spindle protein CHICA) FAM83D C20orf129 Homo sapiens (Human) cell division [GO:0051301]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; epithelial to mesenchymal transition [GO:0001837]; metaphase plate congression [GO:0051310]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; protein localization to mitotic spindle [GO:1902480]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein catabolic process [GO:0042176]; regulation of TOR signaling [GO:0032006]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; microtubule cytoskeleton [GO:0015630]; mitotic spindle [GO:0072686]; mitotic spindle pole [GO:0097431]; spindle [GO:0005819] kinesin binding [GO:0019894]; microtubule binding [GO:0008017]; protein kinase binding [GO:0019901] 0.81039 0.22546 DVALYPSYQ 0 0 0 0 0 0 11.877 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H4I2 ZHX3_HUMAN Zinc fingers and homeoboxes protein 3 (Triple homeobox protein 1) (Zinc finger and homeodomain protein 3) ZHX3 KIAA0395 TIX1 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]" 0.9598 -1.9247 KSTTPCMIPVK 0 0 0 0 0 0 0 0 0 0 0 10.9461 0 0 0 0 0 0 0 10.2037 0 0 0 10.0768 0 0 0 Q9H4I3 TRABD_HUMAN TraB domain-containing protein (Protein TTG2) TRABD TTG2 PP2447 Homo sapiens (Human) 0.92735 -1.1867 EVQPDVVVVELCQYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.53384 0 0 0 0 Q9H4I8 SEHL2_HUMAN Serine hydrolase-like protein 2 (EC 3.1.-.-) SERHL2 SERHL Homo sapiens (Human) perinuclear region of cytoplasm [GO:0048471]; peroxisome [GO:0005777] hydrolase activity [GO:0016787] 0.82587 0.21431 AVHGYFDSR 0 0 0 0 0 0 10.295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H4K1 RIBC2_HUMAN RIB43A-like with coiled-coils protein 2 RIBC2 C22orf11 Homo sapiens (Human) axonemal microtubule [GO:0005879]; nucleus [GO:0005634] 0.29933 0.81329 AINDFQQSFQKPETR 9.05664 8.52834 8.99726 0 0 0 8.9706 0 8.74282 8.80281 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H4L5 OSBL3_HUMAN Oxysterol-binding protein-related protein 3 (ORP-3) (OSBP-related protein 3) OSBPL3 KIAA0704 ORP3 OSBP3 Homo sapiens (Human) bile acid biosynthetic process [GO:0006699] cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; filopodium tip [GO:0032433]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nuclear membrane [GO:0031965]; perinuclear endoplasmic reticulum [GO:0097038]; plasma membrane [GO:0005886] cholesterol binding [GO:0015485]; sterol transporter activity [GO:0015248] 0.96304 -2.6566 IEQLQRER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.81548 Q9H4L7 SMRCD_HUMAN SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.4.12) (ATP-dependent helicase 1) (hHEL1) SMARCAD1 KIAA1122 Homo sapiens (Human) chromatin remodeling [GO:0006338]; chromosome separation [GO:0051304]; DNA double-strand break processing [GO:0000729]; regulation of DNA recombination [GO:0000018] heterochromatin [GO:0000792]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861] "ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent activity, acting on DNA [GO:0008094]; ATP-dependent chromatin remodeler activity [GO:0140658]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; helicase activity [GO:0004386]; ubiquitin binding [GO:0043130]" 0.96976 -4.6661 EVSSRSQNYPK 0 0 0 0 0 0 0 0 0 11.9658 0 10.3699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H4M7 PKHA4_HUMAN Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1) PLEKHA4 PEPP1 Homo sapiens (Human) "positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]" cytoplasm [GO:0005737]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; plasma membrane [GO:0005886] "identical protein binding [GO:0042802]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]" 0.96972 -3.305 ATLCHLTQERER 10.925 0 0 0 0 0 0 11.7045 13.4164 0 0 0 0 9.33586 0 0 0 0 0 0 0 0 0 0 0 9.88004 11.2486 Q9H4M9 EHD1_HUMAN EH domain-containing protein 1 (PAST homolog 1) (hPAST1) (Testilin) EHD1 PAST PAST1 CDABP0131 Homo sapiens (Human) cellular response to nerve growth factor stimulus [GO:1990090]; cholesterol homeostasis [GO:0042632]; cilium assembly [GO:0060271]; endocytic recycling [GO:0032456]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; low-density lipoprotein particle clearance [GO:0034383]; neuron projection development [GO:0031175]; positive regulation of cholesterol storage [GO:0010886]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of neuron projection development [GO:0010976]; protein homooligomerization [GO:0051260]; protein localization to cilium [GO:0061512]; protein localization to plasma membrane [GO:0072659] ciliary pocket membrane [GO:0020018]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet dense tubular network membrane [GO:0031095]; recycling endosome membrane [GO:0055038] ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; small GTPase binding [GO:0031267] 0.88139 -0.30275 MFSWVSKDAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0385 0 0 0 0 Q9H4Q3 PRD13_HUMAN PR domain zinc finger protein 13 (EC 2.1.1.-) (PR domain-containing protein 13) PRDM13 PFM10 Homo sapiens (Human) GABAergic neuron differentiation [GO:0097154]; hypothalamus cell differentiation [GO:0021979]; methylation [GO:0032259]; negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; histone methyltransferase activity [GO:0042054]; metal ion binding [GO:0046872]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629] 0.91366 -0.78276 HIRLHAEGNTPYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4815 0 0 0 0 0 0 0 0 0 0 0 Q9H4T2 ZSC16_HUMAN Zinc finger and SCAN domain-containing protein 16 (Zinc finger protein 392) (Zinc finger protein 435) ZSCAN16 ZNF392 ZNF435 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.96807 -3.6819 EFLGEINDR 0 8.81449 0 0 0 0 0 0 0 9.26672 0 0 0 0 9.1375 0 0 0 0 9.5648 0 8.91973 0 8.57043 9.68001 0 0 Q9H4Y5 GSTO2_HUMAN Glutathione S-transferase omega-2 (GSTO-2) (EC 2.5.1.18) (Glutathione S-transferase omega 2-2) (GSTO 2-2) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1) (Monomethylarsonic acid reductase) (MMA(V) reductase) (EC 1.20.4.2) GSTO2 Homo sapiens (Human) cellular response to arsenic-containing substance [GO:0071243]; glutathione metabolic process [GO:0006749]; L-ascorbic acid metabolic process [GO:0019852]; xenobiotic metabolic process [GO:0006805] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062] glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491] 0.82978 0.20875 MLLELFCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.96454 9.84543 0 0 0 0 0 0 Q9H4Z2 ZN335_HUMAN Zinc finger protein 335 (NRC-interacting factor 1) (NIF-1) ZNF335 Homo sapiens (Human) brain development [GO:0007420]; brain morphogenesis [GO:0048854]; cerebral cortex neuron differentiation [GO:0021895]; epigenetic regulation of gene expression [GO:0040029]; in utero embryonic development [GO:0001701]; neuron projection morphogenesis [GO:0048812]; positive regulation of lymphocyte proliferation [GO:0050671]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neurogenesis [GO:0050769]; regulation of gene expression [GO:0010468] histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] histone methyltransferase binding [GO:1990226]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; transcription cis-regulatory region binding [GO:0000976] 0.95894 -1.8729 CEFCEFVCEDK 0 0 13.2683 11.0429 9.12195 11.0374 15.245 0 15.3238 15.6938 15.6353 14.9111 10.108 11.3713 10.6791 11.0389 10.627 10.0297 0 0 0 0 0 0 0 0 0 Q9H501 ESF1_HUMAN ESF1 homolog (ABT1-associated protein) ESF1 ABTAP C20orf6 HDCMC28P Homo sapiens (Human) rRNA processing [GO:0006364] extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] RNA binding [GO:0003723] 0.96921 -4.4769 ELDKDAPR 0 0 0 0 0 0 0 0 0 0 9.69662 9.14756 9.47454 0 0 0 0 11.9853 0 0 0 0 0 0 0 0 0 Q9H521 YM006_HUMAN Putative uncharacterized protein LOC645739 Homo sapiens (Human) 0.55822 0.54579 EGEMEVAMQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.53572 0 9.20376 0 0 0 0 0 10.8826 Q9H553 ALG2_HUMAN "Alpha-1,3/1,6-mannosyltransferase ALG2 (EC 2.4.1.132) (EC 2.4.1.257) (Asparagine-linked glycosylation protein 2 homolog) (GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase) (GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase) (GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase)" ALG2 UNQ666/PRO1298 Homo sapiens (Human) dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; oligosaccharide-lipid intermediate biosynthetic process [GO:0006490]; protein glycosylation [GO:0006486]; response to calcium ion [GO:0051592] cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] "alpha-1,3-mannosyltransferase activity [GO:0000033]; calcium-dependent protein binding [GO:0048306]; GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity [GO:0004378]; GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity [GO:0102704]; protein heterodimerization activity [GO:0046982]" 0.96886 -7.6931 ATMGLAGRAR 0 0 0 0 0 0 0 0 13.2 0 10.8946 0 0 0 0 8.96327 0 0 0 0 10.7221 0 0 0 0 0 0 Q9H568 ACTL8_HUMAN Actin-like protein 8 (Cancer/testis antigen 57) (CT57) ACTL8 Homo sapiens (Human) epithelial cell differentiation [GO:0030855]; skeletal muscle thin filament assembly [GO:0030240] actin filament [GO:0005884]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865] 0.36029 0.75042 EEYGEHMR 0 0 0 0 0 0 0 0 0 0 8.853 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.74907 0 Q9H579 MROH8_HUMAN Protein MROH8 (Maestro heat-like repeat-containing protein family member 8) MROH8 C20orf131 C20orf132 Homo sapiens (Human) 0.92453 -1.0327 CHNEPAQEK 0 9.29776 8.69905 0 0 0 0 0 8.77614 8.55171 9.72693 0 11.18 11.2496 0 0 0 0 0 0 10.3192 9.88223 9.77187 9.98939 11.561 11.1317 11.5843 Q9H582 ZN644_HUMAN Zinc finger protein 644 (Zinc finger motif enhancer-binding protein 2) (Zep-2) ZNF644 KIAA1221 ZEP2 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; transcription corepressor binding [GO:0001222]" 0.59187 0.45664 ANSHYLYRHK 0 0 0 0 0 0 0 8.90032 0 0 0 0 0 0 0 0 0 9.66278 0 0 0 0 0 0 0 0 0 Q9H583 HEAT1_HUMAN "HEAT repeat-containing protein 1 (Protein BAP28) (U3 small nucleolar RNA-associated protein 10 homolog) [Cleaved into: HEAT repeat-containing protein 1, N-terminally processed]" HEATR1 BAP28 UTP10 Homo sapiens (Human) "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; positive regulation of rRNA processing [GO:2000234]; positive regulation of transcription by RNA polymerase I [GO:0045943]; ribosomal small subunit biogenesis [GO:0042274]" 90S preribosome [GO:0030686]; fibrillar center [GO:0001650]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040]; t-UTP complex [GO:0034455] RNA binding [GO:0003723]; snoRNA binding [GO:0030515] 0.96823 -2.7809 AKPLGTVQQK 10.3875 0 0 0 0 0 10.9373 10.4056 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H596 DUS21_HUMAN Dual specificity protein phosphatase 21 (EC 3.1.3.16) (EC 3.1.3.48) (Low molecular weight dual specificity phosphatase 21) (LMW-DSP21) DUSP21 LMWDSP21 Homo sapiens (Human) peptidyl-tyrosine dephosphorylation [GO:0035335] cytoplasm [GO:0005737]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; nucleus [GO:0005634] MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; myosin phosphatase activity [GO:0017018]; protein tyrosine phosphatase activity [GO:0004725] 0.80164 0.23943 TLLHCMAGVSR 0 0 0 0 0 0 10.5937 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H5F2 CFA68_HUMAN Cilia- and flagella-associated protein 68 CFAP68 C11orf1 Homo sapiens (Human) axoneme [GO:0005930]; nucleoplasm [GO:0005654] 0.84896 0.1152 TLMGNWNQERYDLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1525 0 0 0 0 0 0 0 0 0 0 0 0 Q9H5I1 SUV92_HUMAN Histone-lysine N-methyltransferase SUV39H2 (EC 2.1.1.355) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Lysine N-methyltransferase 1B) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2) SUV39H2 KMT1B Homo sapiens (Human) "cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cellular response to hypoxia [GO:0071456]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; circadian rhythm [GO:0007623]; histone lysine methylation [GO:0034968]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription by RNA polymerase II [GO:0000122]" "chromatin [GO:0000785]; chromosome, centromeric region [GO:0000775]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]" histone H3K9 methyltransferase activity [GO:0046974]; histone H3K9 trimethyltransferase activity [GO:0140949]; S-adenosyl-L-methionine binding [GO:1904047]; transcription cis-regulatory region binding [GO:0000976]; zinc ion binding [GO:0008270] 0.92513 -1.1765 WQDELNRRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1996 Q9H5I5 PIEZ2_HUMAN Piezo-type mechanosensitive ion channel component 2 (Protein FAM38B) PIEZO2 C18orf30 C18orf58 FAM38B Homo sapiens (Human) cellular response to mechanical stimulus [GO:0071260]; detection of mechanical stimulus [GO:0050982]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; monoatomic cation transport [GO:0006812]; regulation of membrane potential [GO:0042391]; response to mechanical stimulus [GO:0009612] plasma membrane [GO:0005886] mechanosensitive monoatomic ion channel activity [GO:0008381]; monoatomic cation channel activity [GO:0005261] 0.96278 -2.5326 EADKQKAK 0 0 15.6527 0 0 0 0 0 0 0 0 8.39485 0 0 0 0 10.9287 10.5669 0 11.9848 11.9799 0 0 0 0 12.3661 12.2015 Q9H5L6 THAP9_HUMAN DNA transposase THAP9 (EC 2.7.7.-) (THAP domain-containing protein 9) (hTh9) THAP9 Homo sapiens (Human) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; DNA transposition [GO:0006313] DNA binding [GO:0003677]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transferase activity [GO:0016740]; transposase activity [GO:0004803] 0.963 -2.6355 DTVLSRER 0 9.13414 0 0 0 0 0 0 10.6092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H5N1 RABE2_HUMAN Rab GTPase-binding effector protein 2 (Rabaptin-5beta) RABEP2 RABPT5B Homo sapiens (Human) cell projection organization [GO:0030030]; endocytosis [GO:0006897]; protein transport [GO:0015031]; regulation of cilium assembly [GO:1902017] centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytosol [GO:0005829]; early endosome [GO:0005769]; intracellular membrane-bounded organelle [GO:0043231] growth factor activity [GO:0008083]; GTPase activator activity [GO:0005096] 0.58998 0.46157 EIVLPMEK 11.0331 11.0453 11.5009 0 9.15421 0 10.8336 12.2403 10.7812 10.2905 10.2789 10.3894 9.8117 9.5273 9.55808 10.0192 9.68382 9.74265 0 0 0 0 0 0 9.31438 0 0 Q9H5Q4 TFB2M_HUMAN "Dimethyladenosine transferase 2, mitochondrial (EC 2.1.1.-) (Hepatitis C virus NS5A-transactivated protein 5) (HCV NS5A-transactivated protein 5) (Mitochondrial 12S rRNA dimethylase 2) (Mitochondrial transcription factor B2) (h-mtTFB) (h-mtTFB2) (hTFB2M) (mtTFB2) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2)" TFB2M NS5ATP5 Homo sapiens (Human) mitochondrial transcription [GO:0006390]; rRNA methylation [GO:0031167]; transcription initiation at mitochondrial promoter [GO:0006391] mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739] "mitochondrial transcription factor activity [GO:0034246]; RNA binding [GO:0003723]; rRNA (adenine-N6,N6-)-dimethyltransferase activity [GO:0000179]" 0.96963 -3.1272 ELLDQLQQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7.94468 0 0 Q9H5U6 ZCHC4_HUMAN rRNA N6-adenosine-methyltransferase ZCCHC4 (EC 2.1.1.-) (Zinc finger CCHC domain-containing protein 4) ZCCHC4 Homo sapiens (Human) positive regulation of translation [GO:0045727]; rRNA methylation [GO:0031167] cytoplasm [GO:0005737]; nucleolus [GO:0005730] nucleic acid binding [GO:0003676]; rRNA (adenine-N6-)-methyltransferase activity [GO:0008988]; S-adenosyl-L-methionine binding [GO:1904047]; zinc ion binding [GO:0008270] 0.89074 -0.46317 TGRKQSPVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.08212 0 0 0 0 0 0 0 0 0 0 0 0 Q9H5Y7 SLIK6_HUMAN SLIT and NTRK-like protein 6 SLITRK6 Homo sapiens (Human) adult locomotory behavior [GO:0008344]; auditory behavior [GO:0031223]; auditory receptor cell morphogenesis [GO:0002093]; axonogenesis [GO:0007409]; cochlea development [GO:0090102]; innervation [GO:0060384]; lens development in camera-type eye [GO:0002088]; linear vestibuloocular reflex [GO:0060007]; multicellular organism growth [GO:0035264]; positive regulation of synapse assembly [GO:0051965]; regulation of presynapse assembly [GO:1905606]; sensory perception of sound [GO:0007605]; startle response [GO:0001964]; synapse assembly [GO:0007416]; vestibulocochlear nerve development [GO:0021562]; visual perception [GO:0007601] cell surface [GO:0009986]; plasma membrane [GO:0005886] 0.57433 0.478 ELQQLGITEYLR 0 0 0 9.49045 0 9.35955 0 0 0 0 0 0 0 0 0 0 10.6173 0 0 0 0 8.51487 0 0 0 0 0 Q9H5Z6 F124B_HUMAN Protein FAM124B FAM124B Homo sapiens (Human) mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] 0.96592 -2.3057 LYEMILQREATLQK 0 0 9.61752 0 0 9.05265 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H611 PIF1_HUMAN ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1) (PIF1/RRM3 DNA helicase-like protein) PIF1 C15orf20 Homo sapiens (Human) DNA recombination [GO:0006310]; DNA repair [GO:0006281]; mitochondrial genome maintenance [GO:0000002]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; regulation of telomere maintenance [GO:0032204]; telomere maintenance via telomerase [GO:0007004] "chromosome, telomeric region [GO:0000781]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]" 5'-3' DNA helicase activity [GO:0043139]; 5'-3' DNA/RNA helicase activity [GO:0033678]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; G-quadruplex DNA binding [GO:0051880]; magnesium ion binding [GO:0000287]; single-stranded DNA helicase activity [GO:0017116]; telomerase inhibitor activity [GO:0010521]; telomeric DNA binding [GO:0042162] 0.92163 -1.1382 AATRVPDTTLVK 0 0 12.305 0 0 0 0 0 0 0 0 0 0 0 0 10.0112 0 0 0 0 0 0 0 0 0 0 0 Q9H628 RERGL_HUMAN Ras-related and estrogen-regulated growth inhibitor-like protein (EC 3.6.5.2) (RERG/Ras-like protein) RERGL Homo sapiens (Human) G protein activity [GO:0003925]; GTP binding [GO:0005525] 0.91072 -0.7482 MSNFLHLKYNEK 0 0 0 0 0 0 0 8.72079 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H633 RPP21_HUMAN Ribonuclease P protein subunit p21 (RNaseP protein p21) (Ribonuclease P/MRP 21 kDa subunit) (Ribonucleoprotein V) RPP21 C6orf135 CAT60 Homo sapiens (Human) response to xenobiotic stimulus [GO:0009410]; tRNA 5'-leader removal [GO:0001682]; tRNA processing [GO:0008033] multimeric ribonuclease P complex [GO:0030681]; nucleolar ribonuclease P complex [GO:0005655]; nucleoplasm [GO:0005654] metal ion binding [GO:0046872]; ribonuclease P activity [GO:0004526]; ribonuclease P RNA binding [GO:0033204] 0.95944 -1.7299 DPSVKRTLCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2716 10.4116 0 0 0 0 0 0 0 Q9H649 NSUN3_HUMAN "tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 3)" NSUN3 MSTP077 UG0651E06 Homo sapiens (Human) regulation of mitochondrial translation [GO:0070129]; rRNA methylation [GO:0031167]; tRNA wobble base cytosine methylation [GO:0002127] mitochondrial large ribosomal subunit [GO:0005762]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] methyltransferase activity [GO:0008168]; tRNA (cytosine-5-)-methyltransferase activity [GO:0016428]; tRNA binding [GO:0000049] 0.88273 -0.11223 QICKVVLDHFEKQYSK 0 0 0 0 0 0 0 0 0 0 0 0 0 8.86477 0 0 0 0 0 0 0 0 0 0 0 0 11.1684 Q9H665 IGFR1_HUMAN IGF-like family receptor 1 (Transmembrane protein 149) (U2 small nuclear RNA auxiliary factor 1-like 4) IGFLR1 TMEM149 U2AF1L4 Homo sapiens (Human) nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] 0.3602 0.74937 ALIEMVVAR 11.7231 11.4915 11.5122 8.39356 0 0 11.5687 0 11.5608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H668 STN1_HUMAN CST complex subunit STN1 (Oligonucleotide/oligosaccharide-binding fold-containing protein 1) (Suppressor of cdc thirteen homolog) STN1 OBFC1 Homo sapiens (Human) DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nucleotide-excision repair [GO:0006289]; positive regulation of DNA replication [GO:0045740]; telomere capping [GO:0016233]; telomere maintenance [GO:0000723]; telomere maintenance via telomere lengthening [GO:0010833] "chromosome, telomeric region [GO:0000781]; CST complex [GO:1990879]; DNA replication factor A complex [GO:0005662]; fibrillar center [GO:0001650]; intermediate filament cytoskeleton [GO:0045111]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]" single-stranded DNA binding [GO:0003697]; single-stranded telomeric DNA binding [GO:0043047]; telomeric DNA binding [GO:0042162] 0.54521 0.56911 QVPGVFLYNGHPIK 0 0 0 9.29756 9.4204 9.56609 0 0 0 11.5754 11.1051 11.1684 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H6A0 DEN2D_HUMAN DENN domain-containing protein 2D DENND2D Homo sapiens (Human) cytosol [GO:0005829]; nucleoplasm [GO:0005654] guanyl-nucleotide exchange factor activity [GO:0005085] 0.88826 -0.43197 MEGQVVGRVFRLFQR 0 0 0 0 10.2016 0 0 0 0 0 0 0 0 0 9.50752 0 0 0 0 0 0 0 0 0 0 0 0 Q9H6A9 PCX3_HUMAN Pecanex-like protein 3 (Pecanex homolog protein 3) PCNX3 PCNXL3 Homo sapiens (Human) membrane [GO:0016020] 0.88319 -0.042655 GAAGGPR 0 0 0 0 0 0 9.40546 0 0 0 0 11.0637 0 0 0 0 0 0 8.7186 0 0 9.42236 0 9.7155 9.19168 0 0 Q9H6B1 Z385D_HUMAN Zinc finger protein 385D (Zinc finger protein 659) ZNF385D ZNF659 Homo sapiens (Human) nucleus [GO:0005634] sequence-specific double-stranded DNA binding [GO:1990837]; zinc ion binding [GO:0008270] 0.95913 -1.7161 HKTMLEAR 0 0 0 9.93737 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H6B4 CLMP_HUMAN CXADR-like membrane protein (Adipocyte adhesion molecule) (Coxsackie- and adenovirus receptor-like membrane protein) (CAR-like membrane protein) CLMP ACAM ASAM UNQ318/PRO363 Homo sapiens (Human) digestive tract development [GO:0048565] bicellular tight junction [GO:0005923]; cell surface [GO:0009986]; cytoplasmic microtubule [GO:0005881]; plasma membrane [GO:0005886] 0.69202 0.38534 LVKPSSSSSGSR 0 0 0 0 0 0 9.57928 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H6B9 EPHX3_HUMAN Epoxide hydrolase 3 (EH3) (EC 3.3.2.10) (Abhydrolase domain-containing protein 9) EPHX3 ABHD9 Homo sapiens (Human) epoxide metabolic process [GO:0097176]; lipid metabolic process [GO:0006629] endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020] epoxide hydrolase activity [GO:0004301]; hydrolase activity [GO:0016787] 0.5124 0.60133 PELVVTALLAPSRLSLKLLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0428 0 0 Q9H6D7 HAUS4_HUMAN HAUS augmin-like complex subunit 4 HAUS4 C14orf94 Homo sapiens (Human) cell division [GO:0051301]; centrosome cycle [GO:0007098]; spindle assembly [GO:0051225] centrosome [GO:0005813]; cytosol [GO:0005829]; HAUS complex [GO:0070652]; mitotic spindle microtubule [GO:1990498] microtubule minus-end binding [GO:0051011] 0.56396 0.49554 ILSDTYTVEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.97321 0 Q9H6E5 STPAP_HUMAN Speckle targeted PIP5K1A-regulated poly(A) polymerase (Star-PAP) (EC 2.7.7.19) (RNA-binding motif protein 21) (RNA-binding protein 21) (U6 snRNA-specific terminal uridylyltransferase 1) (U6-TUTase) (EC 2.7.7.52) TUT1 RBM21 Homo sapiens (Human) mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; snRNA processing [GO:0016180]; U6 snRNA 3'-end processing [GO:0034477] cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] ATP binding [GO:0005524]; enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; mRNA 3'-UTR binding [GO:0003730]; poly(A) RNA polymerase activity [GO:1990817]; RNA binding [GO:0003723]; RNA uridylyltransferase activity [GO:0050265]; U6 snRNA binding [GO:0017070] 0.80034 0.23929 GAAPDSHQLAK 0 0 0 0 0 0 0 0 0 0 0 0 8.74029 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H6H4 REEP4_HUMAN Receptor expression-enhancing protein 4 REEP4 C8orf20 PP432 Homo sapiens (Human) cell division [GO:0051301]; endoplasmic reticulum tubular network organization [GO:0071786]; mitotic nuclear membrane reassembly [GO:0007084]; nuclear envelope organization [GO:0006998] cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum tubular network [GO:0071782] microtubule binding [GO:0008017] 0.7942 0.24498 EIDAYIVQAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7399 0 0 0 0 0 0 0 0 0 0 0 0 Q9H6I2 SOX17_HUMAN Transcription factor SOX-17 SOX17 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; cardiac cell fate determination [GO:0060913]; cardiogenic plate morphogenesis [GO:0003142]; cell migration involved in gastrulation [GO:0042074]; cellular response to leukemia inhibitory factor [GO:1990830]; common bile duct development [GO:0061009]; embryonic foregut morphogenesis [GO:0048617]; embryonic heart tube development [GO:0035050]; embryonic heart tube morphogenesis [GO:0003143]; endocardial cell differentiation [GO:0060956]; endocardium formation [GO:0060214]; endoderm formation [GO:0001706]; endodermal cell fate determination [GO:0007493]; endodermal cell fate specification [GO:0001714]; endodermal digestive tract morphogenesis [GO:0061031]; gallbladder development [GO:0061010]; heart development [GO:0007507]; heart formation [GO:0060914]; heart looping [GO:0001947]; inner cell mass cellular morphogenesis [GO:0001828]; metanephros development [GO:0001656]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; negative regulation of Wnt signaling pathway involved in heart development [GO:0003308]; outflow tract morphogenesis [GO:0003151]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endodermal cell differentiation [GO:1903226]; positive regulation of gene expression [GO:0010628]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of stem cell differentiation [GO:2000738]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein destabilization [GO:0031648]; protein stabilization [GO:0050821]; regulation of cardiac cell fate specification [GO:2000043]; regulation of DNA-templated transcription [GO:0006355]; regulation of embryonic development [GO:0045995]; regulation of stem cell division [GO:2000035]; regulation of stem cell proliferation [GO:0072091]; regulation of transcription by RNA polymerase II [GO:0006357]; rostrocaudal neural tube patterning [GO:0021903]; signal transduction involved in regulation of gene expression [GO:0023019]; spermatogenesis [GO:0007283]; stem cell fate specification [GO:0048866]; ureter development [GO:0072189]; vasculogenesis [GO:0001570]; Wnt signaling pathway [GO:0016055] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "beta-catenin binding [GO:0008013]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription cis-regulatory region binding [GO:0000976]" 0.88372 -0.045037 LAQQNPDLHNAELSKMLGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2125 0 0 0 0 0 10.2924 0 Q9H6K5 PRR36_HUMAN Proline-rich protein 36 PRR36 Homo sapiens (Human) 0.22779 0.86161 APAHPSQPKPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5485 0 0 0 0 0 0 8.4402 Q9H6N6 MYH16_HUMAN Putative uncharacterized protein MYH16 (Myosin heavy chain 16 pseudogene) (myosin heavy polypeptide 5) MYH16 MYH5 Homo sapiens (Human) myosin complex [GO:0016459] 0.96217 -2.5137 DLEINSVNSK 11.3673 0 11.7651 0 8.85941 0 10.5901 8.72823 0 12.5156 0 0 0 0 0 10.9245 0 11.2781 10.7048 9.35017 0 0 0 0 0 0 0 Q9H6Q4 CIAO3_HUMAN Cytosolic iron-sulfur assembly component 3 (Cytosolic Fe-S cluster assembly factor NARFL) (Iron-only hydrogenase-like protein 1) (IOP1) (Nuclear prelamin A recognition factor-like protein) (Protein related to Narf) CIAO3 NARFL PRN Homo sapiens (Human) hematopoietic progenitor cell differentiation [GO:0002244]; intracellular oxygen homeostasis [GO:0032364]; iron-sulfur cluster assembly [GO:0016226]; regulation of gene expression [GO:0010468]; response to hypoxia [GO:0001666] CIA complex [GO:0097361] "4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]" 0.65203 0.39565 AGSGVAK 0 0 0 9.39103 9.63083 0 0 0 0 0 0 0 12.0086 11.9046 0 12.6543 0 0 0 0 0 0 0 0 0 0 0 Q9H6R0 DHX33_HUMAN ATP-dependent RNA helicase DHX33 (EC 3.6.4.13) (DEAH box protein 33) DHX33 DDX33 Homo sapiens (Human) positive regulation of MAPK cascade [GO:0043410]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of type I interferon production [GO:0032481]; translational initiation [GO:0006413] cytoplasm [GO:0005737]; NLRP3 inflammasome complex [GO:0072559]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA-binding transcription factor binding [GO:0140297]; double-stranded RNA binding [GO:0003725]; helicase activity [GO:0004386]; mRNA binding [GO:0003729]; rDNA binding [GO:0000182]; ribosomal large subunit binding [GO:0043023]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.064257 1.3066 AGSFPPGR 0 0 0 0 0 0 0 0 0 11.4697 11.6504 11.6451 0 0 0 0 0 8.75932 0 0 0 0 9.34196 0 0 0 0 Q9H6R3 ACSS3_HUMAN "Acyl-CoA synthetase short-chain family member 3, mitochondrial (EC 6.2.1.1) (Acetate--CoA ligase 3) (Acyl-CoA synthetase short-chain family member 3) (Propionate--CoA ligase) (EC 6.2.1.17)" ACSS3 Homo sapiens (Human) ketone body biosynthetic process [GO:0046951] intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] acetate-CoA ligase activity [GO:0003987]; ATP binding [GO:0005524]; butyrate-CoA ligase activity [GO:0047760]; propionate-CoA ligase activity [GO:0050218] 0.57354 0.47477 DLDWDEEMAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.957 0 0 Q9H6R4 NOL6_HUMAN Nucleolar protein 6 (Nucleolar RNA-associated protein) (Nrap) NOL6 Homo sapiens (Human) ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364]; tRNA export from nucleus [GO:0006409] condensed nuclear chromosome [GO:0000794]; CURI complex [GO:0032545]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040]; UTP-C complex [GO:0034456] RNA binding [GO:0003723] 0.56162 0.50852 GPAPAGEQLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2619 9.95591 0 10.1236 0 0 0 0 0 Q9H6R6 ZDHC6_HUMAN Palmitoyltransferase ZDHHC6 (EC 2.3.1.225) (Stearoyltransferase ZDHHC6) (EC 2.3.1.-) (Transmembrane protein H4) (Zinc finger DHHC domain-containing protein 6) (DHHC-6) (Zinc finger protein 376) ZDHHC6 ZNF376 Homo sapiens (Human) peptidyl-L-cysteine S-palmitoylation [GO:0018230]; positive regulation of mitochondrial fusion [GO:0010636]; protein palmitoylation [GO:0018345]; protein stearoylation [GO:0140438]; protein targeting to membrane [GO:0006612] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794] palmitoyltransferase activity [GO:0016409]; protein-cysteine S-palmitoyltransferase activity [GO:0019706]; protein-cysteine S-stearoyltransferase activity [GO:0140439] 0.88463 -0.19377 GEFILATRGLR 0 0 0 0 9.50353 0 0 0 0 0 0 0 10.0658 0 0 0 0 0 0 0 0 0 0 0 9.73329 0 0 Q9H6S0 YTDC2_HUMAN 3'-5' RNA helicase YTHDC2 (EC 3.6.4.13) (YTH domain-containing protein 2) (hYTHDC2) YTHDC2 Homo sapiens (Human) "germline cell cycle switching, mitotic to meiotic cell cycle [GO:0051729]; meiotic cell cycle [GO:0051321]; oocyte development [GO:0048599]; positive regulation by host of viral genome replication [GO:0044829]; response to interleukin-1 [GO:0070555]; response to tumor necrosis factor [GO:0034612]; spermatid development [GO:0007286]" endoplasmic reticulum [GO:0005783]; perinuclear region of cytoplasm [GO:0048471]; ribonucleoprotein granule [GO:0035770] "3'-5' RNA helicase activity [GO:0034458]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent activity, acting on RNA [GO:0008186]; helicase activity [GO:0004386]; N6-methyladenosine-containing RNA binding [GO:1990247]; RNA binding [GO:0003723]; RNA polymerase binding [GO:0070063]" 0.96791 -3.6842 AGRCRPGICFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.80761 0 10.0261 0 Q9H6T0 ESRP2_HUMAN Epithelial splicing regulatory protein 2 (RNA-binding motif protein 35B) (RNA-binding protein 35B) ESRP2 RBM35B PP7059 Homo sapiens (Human) "alternative mRNA splicing, via spliceosome [GO:0000380]; branching involved in salivary gland morphogenesis [GO:0060445]; epithelial cell proliferation [GO:0050673]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; positive regulation of epithelial cell proliferation [GO:0050679]; regulation of RNA splicing [GO:0043484]" nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] mRNA binding [GO:0003729]; RNA binding [GO:0003723] 0.54653 0.56777 ALAAAQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.97427 0 0 0 0 0 0 0 10.9891 0 Q9H6T3 RPAP3_HUMAN RNA polymerase II-associated protein 3 RPAP3 Homo sapiens (Human) protein stabilization [GO:0050821] cytosol [GO:0005829]; protein folding chaperone complex [GO:0101031]; R2TP complex [GO:0097255]; RPAP3/R2TP/prefoldin-like complex [GO:1990062] 0.77077 0.27432 DCTQAILLDGSYSKAFAR 0 0 10.2538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H6U6 BCAS3_HUMAN BCAS3 microtubule associated cell migration factor (Breast carcinoma-amplified sequence 3) (GAOB1) BCAS3 Homo sapiens (Human) angiogenesis [GO:0001525]; autophagy [GO:0006914]; cell-cell signaling [GO:0007267]; cellular response to estrogen stimulus [GO:0071391]; positive regulation of catalytic activity [GO:0043085]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of actin cytoskeleton organization [GO:0032956]; response to estrogen [GO:0043627]; response to starvation [GO:0042594] cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; euchromatin [GO:0000791]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; phagophore assembly site [GO:0000407] acetyltransferase activator activity [GO:0010698]; beta-tubulin binding [GO:0048487]; chromatin binding [GO:0003682]; histone acetyltransferase binding [GO:0035035]; histone binding [GO:0042393]; nuclear receptor binding [GO:0016922]; phosphatidylinositol binding [GO:0035091] 0.96792 -3.6922 EKIVWVR 0 0 0 0 0 0 13.9342 0 0 9.91163 0 0 0 0 11.0266 0 0 0 0 0 0 0 0 0 0 0 0 Q9H6X2 ANTR1_HUMAN Anthrax toxin receptor 1 (Tumor endothelial marker 8) ANTXR1 ATR TEM8 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; blood vessel development [GO:0001568]; negative regulation of extracellular matrix assembly [GO:1901202]; positive regulation of metallopeptidase activity [GO:1905050]; reproductive process [GO:0022414]; substrate adhesion-dependent cell spreading [GO:0034446]; toxin transport [GO:1901998] cell surface [GO:0009986]; endosome membrane [GO:0010008]; external side of plasma membrane [GO:0009897]; filopodium membrane [GO:0031527]; lamellipodium membrane [GO:0031258]; plasma membrane [GO:0005886] actin filament binding [GO:0051015]; collagen binding [GO:0005518]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888] 0.96411 -2.4349 LEKAKNAR 0 0 8.8867 0 0 0 0 0 8.85792 0 12.8489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H6X5 CS044_HUMAN Uncharacterized protein C19orf44 C19orf44 Homo sapiens (Human) 0.9673 -2.35 IAPGHSRFLKR 0 9.99181 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5113 0 0 0 0 0 0 0 0 0 Q9H6Z4 RANB3_HUMAN Ran-binding protein 3 (RanBP3) RANBP3 Homo sapiens (Human) protein export from nucleus [GO:0006611] cytoplasm [GO:0005737]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] R-SMAD binding [GO:0070412]; small GTPase binding [GO:0031267] 0.952 -1.3853 SRVEQEQEAK 0 0 0 0 0 0 0 0 0 0 0 0 9.27041 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H706 GARE1_HUMAN GRB2-associated and regulator of MAPK protein 1 (GRB2-associated and regulator of MAPK1) GAREM1 C18orf11 FAM59A GAREM Homo sapiens (Human) cellular response to epidermal growth factor stimulus [GO:0071364]; epidermal growth factor receptor signaling pathway [GO:0007173]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] plasma membrane [GO:0005886] proline-rich region binding [GO:0070064] 0.9678 -2.9589 EPVQYFNSVEEVAK 9.59913 9.44348 0 0 0 0 0 0 0 0 9.17105 0 0 9.57732 0 0 9.79737 0 0 0 0 0 0 0 9.26512 0 0 Q9H714 PACER_HUMAN Protein associated with UVRAG as autophagy enhancer (Pacer) (Protein Rubicon-like) RUBCNL C13orf18 KIAA0226L Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagosome-endosome fusion [GO:0061910]; autophagosome-lysosome fusion [GO:0061909]; lipid metabolic process [GO:0006629]; regulation of glycogen metabolic process [GO:0070873]; regulation of lipid metabolic process [GO:0019216] autophagosome membrane [GO:0000421]; cytoplasmic vesicle [GO:0031410]; intracellular membrane-bounded organelle [GO:0043231] phosphatidylinositol phosphate binding [GO:1901981]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314] 0.96938 -3.1902 ILMMWDFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2927 Q9H720 PG2IP_HUMAN PGAP2-interacting protein (Cell wall biogenesis protein 43 C-terminal homolog) CWH43 PGAP2IP Homo sapiens (Human) GPI anchor biosynthetic process [GO:0006506] endoplasmic reticulum [GO:0005783]; membrane [GO:0016020] 0.8207 0.21944 EVSAAIWPFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4069 0 0 0 0 0 0 0 0 0 Q9H756 LRC19_HUMAN Leucine-rich repeat-containing protein 19 LRRC19 Homo sapiens (Human) host-mediated regulation of intestinal microbiota composition [GO:0048874]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cytokine production [GO:0001817]; regulation of inflammatory response [GO:0050727]; toll-like receptor signaling pathway [GO:0002224]; TRAF-mediated signal transduction [GO:0038008] plasma membrane [GO:0005886] signaling receptor activity [GO:0038023] 0.76506 0.28651 CPIWYNILLSYNHHR 0 0 0 0 10.1949 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H765 ASB8_HUMAN Ankyrin repeat and SOCS box protein 8 (ASB-8) ASB8 PP14212 Homo sapiens (Human) intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567] cytosol [GO:0005829] 0.9262 -0.96224 DTPLHWAAFK 0 0 0 0 0 10.1669 0 0 0 12.1944 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7685 Q9H788 SH24A_HUMAN SH2 domain-containing protein 4A (Protein SH(2)A) (Protein phosphatase 1 regulatory subunit 38) SH2D4A PPP1R38 SH2A Homo sapiens (Human) cytoplasm [GO:0005737]; cytosol [GO:0005829] phosphatase binding [GO:0019902] 0.96885 -3.0137 LSLGAQKGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8977 9.56503 0 0 9.37689 0 9.6539 0 9.47131 0 0 Q9H790 EXO5_HUMAN Exonuclease V (Exo V) (hExo5) (EC 3.1.-.-) (Defects in morphology protein 1 homolog) EXO5 C1orf176 DEM1 Homo sapiens (Human) interstrand cross-link repair [GO:0036297] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; single-stranded DNA 3'-5' DNA exonuclease activity [GO:0008310]; single-stranded DNA 5'-3' DNA exonuclease activity [GO:0045145]" 0.95211 -1.4285 KDCFQVSLYKYIFDAMVQGK 0 0 0 0 0 9.8423 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H792 PEAK1_HUMAN Inactive tyrosine-protein kinase PEAK1 (Pseudopodium-enriched atypical kinase 1) (Sugen kinase 269) (Tyrosine-protein kinase SgK269) PEAK1 KIAA2002 Homo sapiens (Human) cell migration [GO:0016477]; focal adhesion assembly [GO:0048041]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of focal adhesion assembly [GO:0051893]; substrate adhesion-dependent cell spreading [GO:0034446] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; focal adhesion [GO:0005925] identical protein binding [GO:0042802]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672] 0.72248 0.36055 DEDDMEETEEDAK 0 15.6832 15.4296 14.4031 14.6698 14.4184 15.7078 15.9124 0 0 0 14.5512 0 15.9823 0 15.994 15.852 0 15.4849 15.5016 15.6574 14.9238 14.4938 14.6563 16.0621 15.8603 15.3123 Q9H799 CPLN1_HUMAN Ciliogenesis and planar polarity effector 1 (Protein JBTS17) CPLANE1 C5orf42 JBTS17 Homo sapiens (Human) cilium assembly [GO:0060271] ciliary transition zone [GO:0035869]; membrane [GO:0016020] 0.97016 -3.257 ALQEIEEK 0 0 0 0 9.87655 0 0 0 0 0 0 0 9.4302 0 0 0 0 0 0 0 0 0 9.78252 0 0 0 11.7349 Q9H7B4 SMYD3_HUMAN Histone-lysine N-methyltransferase SMYD3 (EC 2.1.1.354) (SET and MYND domain-containing protein 3) (Zinc finger MYND domain-containing protein 1) SMYD3 ZMYND1 ZNFN3A1 Homo sapiens (Human) cellular response to dexamethasone stimulus [GO:0071549]; establishment of protein localization [GO:0045184]; histone lysine methylation [GO:0034968]; myotube cell development [GO:0014904]; negative regulation of protein kinase activity [GO:0006469]; nucleosome assembly [GO:0006334]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription by RNA polymerase II [GO:0045944] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] histone H3K36 dimethyltransferase activity [GO:0140954]; histone H3K4 trimethyltransferase activity [GO:0140999]; histone H4 methyltransferase activity [GO:0140939]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding [GO:0001162] 0.96733 -2.798 GVQVMKVGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.77584 0 0 0 9.80445 0 0 0 0 0 0 0 0 Q9H7C9 AAMDC_HUMAN Mth938 domain-containing protein (Adipogenesis associated Mth938 domain-containing protein) AAMDC C11orf67 PTD015 Homo sapiens (Human) positive regulation of fat cell differentiation [GO:0045600] cytoplasm [GO:0005737] 0.81893 0.21909 ETGTEHSPGVQPADVK 0 0 0 9.40998 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H7D0 DOCK5_HUMAN Dedicator of cytokinesis protein 5 DOCK5 Homo sapiens (Human) bone remodeling [GO:0046849]; cell migration [GO:0016477]; myoblast fusion [GO:0007520]; negative regulation of vascular associated smooth muscle contraction [GO:1904694]; podosome assembly [GO:0071800]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; Rac protein signal transduction [GO:0016601] anchoring junction [GO:0070161]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; podosome [GO:0002102] GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; small GTPase binding [GO:0031267] 0.9677 -3.7458 ELKEKVEK 0 9.96939 0 0 0 0 0 10.4032 0 0 0 10.7109 10.0914 10.6185 0 13.3457 9.87662 10.8166 0 0 0 0 0 0 11.5673 11.2909 0 Q9H7D7 WDR26_HUMAN WD repeat-containing protein 26 (CUL4- and DDB1-associated WDR protein 2) (Myocardial ischemic preconditioning up-regulated protein 2) WDR26 CDW2 MIP2 PRO0852 Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] cytoplasm [GO:0005737]; cytosol [GO:0005829]; GID complex [GO:0034657]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151] 0.21694 0.89153 LSQSDEDVIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.2122 0 0 0 0 0 10.5558 0 0 0 Q9H7E2 TDRD3_HUMAN Tudor domain-containing protein 3 TDRD3 Homo sapiens (Human) chromatin organization [GO:0006325]; DNA topological change [GO:0006265] cytosol [GO:0005829]; DNA topoisomerase III-beta-TDRD3 complex [GO:0140225]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; methylated histone binding [GO:0035064]; RNA binding [GO:0003723]; transcription coactivator activity [GO:0003713] 0.96328 -2.137 HPPRNDTRQPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0377 0 0 0 Q9H7E9 CH033_HUMAN UPF0488 protein C8orf33 C8orf33 Homo sapiens (Human) 0.95472 -1.5015 NRASVANGGEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1704 0 0 0 0 Q9H7F0 AT133_HUMAN Polyamine-transporting ATPase 13A3 (ATPase family homolog up-regulated in senescence cells 1) (Putrescine transporting ATPase) (EC 7.6.2.16) ATP13A3 AFURS1 Homo sapiens (Human) intracellular calcium ion homeostasis [GO:0006874]; polyamine transmembrane transport [GO:1902047] early endosome membrane [GO:0031901]; late endosome membrane [GO:0031902]; membrane [GO:0016020]; recycling endosome membrane [GO:0055038] ABC-type putrescine transporter activity [GO:0015594]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled monoatomic cation transmembrane transporter activity [GO:0019829]; metal ion binding [GO:0046872]; P-type transmembrane transporter activity [GO:0140358]; polyamine transmembrane transporter activity [GO:0015203] 0.88158 -0.31056 ISKYSQTESQQIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2466 0 0 9.03177 0 0 0 0 0 Q9H7H0 MET17_HUMAN "Methyltransferase-like protein 17, mitochondrial (EC 2.1.1.-) (False p73 target gene protein) (Methyltransferase 11 domain-containing protein 1) (Protein RSM22 homolog, mitochondrial)" METTL17 METT11D1 Homo sapiens (Human) methylation [GO:0032259]; ribosomal small subunit biogenesis [GO:0042274]; translation [GO:0006412] mitochondrial matrix [GO:0005759]; nucleoplasm [GO:0005654] methyltransferase activity [GO:0008168]; S-adenosyl-L-methionine binding [GO:1904047] 0.56759 0.48447 FLENPDLSQTEEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8338 0 0 0 0 0 0 0 0 11.1317 0 Q9H7L2 KI3X1_HUMAN Putative killer cell immunoglobulin-like receptor-like protein KIR3DX1 (Leukocyte receptor cluster member 12) KIR3DX1 KIR3DL0 LENG12 Homo sapiens (Human) extracellular region [GO:0005576] 0.59465 0.44738 EAFQANFSVGR 0 0 0 9.34447 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.47102 0 Q9H7M6 ZSWM4_HUMAN Zinc finger SWIM domain-containing protein 4 ZSWIM4 Homo sapiens (Human) Cul2-RING ubiquitin ligase complex [GO:0031462] zinc ion binding [GO:0008270] 0.78776 0.24987 HYGDFIEFLGK 0 0 0 0 0 0 0 0 0 8.99215 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H7N4 SFR19_HUMAN "Splicing factor, arginine/serine-rich 19 (SR-related C-terminal domain-associated factor 1) (SR-related and CTD-associated factor 1) (SR-related-CTD-associated factor) (SCAF) (Serine arginine-rich pre-mRNA splicing factor SR-A1) (SR-A1)" SCAF1 SFRS19 SRA1 Homo sapiens (Human) mRNA processing [GO:0006397]; RNA splicing [GO:0008380]; transcription by RNA polymerase II [GO:0006366] nucleus [GO:0005634] protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA polymerase II C-terminal domain binding [GO:0099122] 0.96206 -2.6235 ALDGGDR 0 9.75647 0 0 9.81144 9.82466 0 0 11.8772 0 0 0 11.6148 0 0 0 8.60118 0 0 8.87845 9.23264 9.15059 0 0 0 0 0 Q9H7P9 PKHG2_HUMAN Pleckstrin homology domain-containing family G member 2 (PH domain-containing family G member 2) PLEKHG2 Homo sapiens (Human) regulation of actin filament polymerization [GO:0030833] cytosol [GO:0005829] guanyl-nucleotide exchange factor activity [GO:0005085]; small GTPase binding [GO:0031267] 0.95617 -1.5417 DPGPSTHDIPK 0 0 8.46385 0 0 0 0 0 0 10.8107 0 0 0 0 11.5468 0 8.26547 0 0 0 0 0 10.933 0 0 0 0 Q9H7S9 ZN703_HUMAN Zinc finger protein 703 (Zinc finger elbow-related proline domain protein 1) ZNF703 ZEPPO1 ZPO1 Homo sapiens (Human) adherens junction assembly [GO:0034333]; cellular response to estradiol stimulus [GO:0071392]; mammary gland epithelial cell differentiation [GO:0060644]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of mammary gland epithelial cell proliferation [GO:0033601]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of cell cycle [GO:0051726]; regulation of DNA-templated transcription [GO:0006355]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015] cytoplasm [GO:0005737]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] DNA-binding transcription factor binding [GO:0140297]; metal ion binding [GO:0046872] 0.91349 -0.75955 QLGDSPAEDKSSFKPYSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9405 0 0 0 0 0 0 0 0 0 Q9H7T0 CTSRB_HUMAN Cation channel sperm-associated auxiliary subunit beta (CatSper-beta) CATSPERB C14orf161 Homo sapiens (Human) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] CatSper complex [GO:0036128]; cilium [GO:0005929]; plasma membrane [GO:0005886]; sperm principal piece [GO:0097228] 0.96952 -4.7934 KVLQHTTPK 0 12.2356 0 0 0 0 0 8.9238 0 0 0 0 0 0 0 0 0 0 0 0 10.6328 0 0 0 0 0 0 Q9H7U1 CCSE2_HUMAN Serine-rich coiled-coil domain-containing protein 2 (Coiled-coil serine-rich protein 2) (Protein GCAP14 homolog) CCSER2 FAM190B KIAA1128 NPD012 Homo sapiens (Human) microtubule bundle formation [GO:0001578] cytoplasm [GO:0005737]; microtubule cytoskeleton [GO:0015630] microtubule binding [GO:0008017] 0.92292 -1.0787 ITPEEMSLK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.2369 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H7Z3 NRDE2_HUMAN Nuclear exosome regulator NRDE2 (Protein NRDE2 homolog) NRDE2 C14orf102 Homo sapiens (Human) cell division [GO:0051301]; DNA damage response [GO:0006974]; mitotic cell cycle [GO:0000278]; mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of RNA catabolic process [GO:1902369]; positive regulation of RNA export from nucleus [GO:0046833]; RNA splicing [GO:0008380]; small ncRNA-mediated heterochromatin formation [GO:0031048] nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.95971 -1.909 GVFYKALQNCPWAK 0 0 0 0 0 0 9.42206 9.45596 9.28815 0 0 0 8.5789 0 10.053 0 8.97671 0 0 0 0 0 0 0 0 0 0 Q9H7Z6 KAT8_HUMAN "Histone acetyltransferase KAT8 (EC 2.3.1.48) (Lysine acetyltransferase 8) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (MYST-1) (hMOF)" KAT8 MOF MYST1 PP7073 Homo sapiens (Human) histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; myeloid cell differentiation [GO:0030099]; negative regulation of DNA-templated transcription [GO:0045892]; neurogenesis [GO:0022008]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of histone H3-K4 methylation [GO:0051571]; regulation of autophagy [GO:0010506]; regulation of dosage compensation by inactivation of X chromosome [GO:1900095] histone acetyltransferase complex [GO:0000123]; kinetochore [GO:0000776]; MLL1 complex [GO:0071339]; MSL complex [GO:0072487]; NSL complex [GO:0044545]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] enzyme binding [GO:0019899]; histone H4K16 acetyltransferase activity [GO:0046972]; metal ion binding [GO:0046872]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription coactivator activity [GO:0003713] 0.89293 -0.51337 TVKDAVQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2429 0 0 0 0 0 0 0 0 0 0 Q9H7Z7 PGES2_HUMAN Prostaglandin E synthase 2 (EC 5.3.99.3) (Membrane-associated prostaglandin E synthase-2) (mPGE synthase-2) (Microsomal prostaglandin E synthase 2) (mPGES-2) (Prostaglandin-H(2) E-isomerase) [Cleaved into: Prostaglandin E synthase 2 truncated form] PTGES2 C9orf15 PGES2 Homo sapiens (Human) cyclooxygenase pathway [GO:0019371]; lipid metabolic process [GO:0006629]; positive regulation of DNA-templated transcription [GO:0045893]; secretion [GO:0046903] azurophil granule lumen [GO:0035578]; cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] 12-hydroxyheptadecatrienoic acid synthase activity [GO:0036134]; DNA binding [GO:0003677]; glutathione binding [GO:0043295]; heme binding [GO:0020037]; lyase activity [GO:0016829]; prostaglandin-E synthase activity [GO:0050220] 0.96967 -3.5274 EARTEEMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.61798 0 0 9.76719 0 0 0 0 Q9H814 PHAX_HUMAN Phosphorylated adapter RNA export protein (RNA U small nuclear RNA export adapter protein) PHAX RNUXA Homo sapiens (Human) protein transport [GO:0015031]; RNA stabilization [GO:0043489]; snRNA export from nucleus [GO:0006408] Cajal body [GO:0015030]; cytosol [GO:0005829]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] mRNA cap binding complex binding [GO:0140262]; RNA binding [GO:0003723]; toxic substance binding [GO:0015643] 0.80838 0.23075 SLNFQEDDDTSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.27543 9.21194 9.00422 0 0 0 0 0 0 Q9H816 DCR1B_HUMAN 5' exonuclease Apollo (EC 3.1.-.-) (Beta-lactamase DCLRE1B) (EC 3.5.2.6) (DNA cross-link repair 1B protein) (SNM1 homolog B) (SNMIB) (hSNM1B) DCLRE1B SNM1B Homo sapiens (Human) double-strand break repair via nonhomologous end joining [GO:0006303]; interstrand cross-link repair [GO:0036297]; protection from non-homologous end joining at telomere [GO:0031848]; telomere capping [GO:0016233]; telomere maintenance [GO:0000723]; telomere maintenance via telomere lengthening [GO:0010833]; telomeric 3' overhang formation [GO:0031860]; telomeric loop formation [GO:0031627] "centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]" 5'-3' DNA exonuclease activity [GO:0035312]; 5'-3' exonuclease activity [GO:0008409]; beta-lactamase activity [GO:0008800]; damaged DNA binding [GO:0003684]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877] 0.89899 -0.59196 AVPFCESQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.8258 0 0 0 0 0 0 0 0 0 0 Q9H819 DJC18_HUMAN DnaJ homolog subfamily C member 18 DNAJC18 Homo sapiens (Human) cellular response to misfolded protein [GO:0071218]; chaperone cofactor-dependent protein refolding [GO:0051085] endoplasmic reticulum membrane [GO:0005789] Hsp70 protein binding [GO:0030544] 0.94812 -1.3637 DYIDYIQTSCWKEKQQK 0 10.2778 0 0 0 0 0 0 10.263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H825 METL8_HUMAN "tRNA N(3)-methylcytidine methyltransferase METTL8, mitochondrial (EC 2.1.1.-) (Methyltransferase-like protein 8) (mRNA N(3)-methylcytidine methyltransferase METTL8) (EC 2.1.1.-)" METTL8 Homo sapiens (Human) mitochondrial tRNA modification [GO:0070900]; mRNA methylation [GO:0080009]; positive regulation of mitochondrial translation [GO:0070131]; tRNA C3-cytosine methylation [GO:0106217] mitochondrion [GO:0005739] mRNA methyltransferase activity [GO:0008174]; tRNA (cytosine-3-)-methyltransferase activity [GO:0052735] 0.96704 -2.837 IHKNKFFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.9497 0 0 0 0 0 10.5162 0 Q9H832 UBE2Z_HUMAN Ubiquitin-conjugating enzyme E2 Z (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme Z) (Uba6-specific E2 conjugating enzyme 1) (Use1) (Ubiquitin carrier protein Z) (Ubiquitin-protein ligase Z) UBE2Z HOYS7 Homo sapiens (Human) apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; positive regulation of apoptotic process [GO:0043065]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; molecular adaptor activity [GO:0060090]; ubiquitin conjugating enzyme activity [GO:0061631] 0.41886 0.67646 GHFDYQSLLMR 0 0 0 0 0 0 0 0 0 10.9818 10.8456 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H857 NT5D2_HUMAN 5'-nucleotidase domain-containing protein 2 (EC 3.1.3.-) NT5DC2 Homo sapiens (Human) 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872] 0.9158 -0.77313 TGAIIPELEREIR 0 0 0 9.79479 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H871 RMD5A_HUMAN E3 ubiquitin-protein transferase RMND5A (EC 2.3.2.27) (P44CTLH) (Protein RMD5 homolog A) RMND5A Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209] cytoplasm [GO:0005737]; GID complex [GO:0034657]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.81739 0.22072 FSGYGQLCER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2812 0 0 0 0 0 0 0 0 0 Q9H892 TTC12_HUMAN Tetratricopeptide repeat protein 12 (TPR repeat protein 12) TTC12 Homo sapiens (Human) axonemal dynein complex assembly [GO:0070286]; sperm axoneme assembly [GO:0007288] centrosome [GO:0005813]; cytoplasm [GO:0005737] 0.96729 -2.3483 AVLETEKR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2928 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H8E8 CSR2B_HUMAN Cysteine-rich protein 2-binding protein (CSRP2-binding protein) (ADA2A-containing complex subunit 2) (ATAC2) (CRP2-binding partner) (CRP2BP) (Lysine acetyltransferase 14) KAT14 CSRP2BP Homo sapiens (Human) histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of DNA-templated transcription [GO:0006355]; regulation of embryonic development [GO:0045995]; regulation of histone deacetylation [GO:0031063]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tubulin deacetylation [GO:0090043] ATAC complex [GO:0140672]; cytoplasm [GO:0005737]; mitotic spindle [GO:0072686]; nucleus [GO:0005634] histone acetyltransferase activity [GO:0004402]; LIM domain binding [GO:0030274] 0.82132 0.21701 QGYFRWKEDICAFIEK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.27587 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H8G1 ZN430_HUMAN Zinc finger protein 430 ZNF430 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; substantia nigra development [GO:0021762] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.75265 0.31028 ENSYQCEECGK 0 11.453 0 9.2213 0 0 0 0 0 0 0 0 0 0 0 10.9585 0 0 0 0 0 0 0 0 0 0 0 Q9H8G2 CAAP1_HUMAN Caspase activity and apoptosis inhibitor 1 (Conserved anti-apoptotic protein) (CAAP) CAAP1 C9orf82 CAAP Homo sapiens (Human) apoptotic process [GO:0006915]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268] 0.057377 1.3706 KLCQEQLELLSEK 0 0 0 0 0 0 0 0 0 11.305 11.2038 11.2515 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H8H0 NOL11_HUMAN Nucleolar protein 11 NOL11 L14 Homo sapiens (Human) maturation of SSU-rRNA [GO:0030490]; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901838] nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; t-UTP complex [GO:0034455] RNA binding [GO:0003723] 0.92403 -1.0233 IETVISDEEVIK 0 0 0 0 9.64149 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H8H2 DDX31_HUMAN Probable ATP-dependent RNA helicase DDX31 (EC 3.6.4.13) (DEAD box protein 31) (Helicain) DDX31 Homo sapiens (Human) ribosome biogenesis [GO:0042254] Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; nucleolus [GO:0005730]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.89845 -0.58699 GGGAGSSR 0 0 0 0 0 0 0 0 0 8.85882 7.97304 0 0 10.1122 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H8H3 TMT1A_HUMAN N6-adenosine-methyltransferase TMT1A (EC 2.1.1.348) (Methyltransferase TMT1A) (Methyltransferase-like protein 7A) (Protein AAM-B) (Thiol methyltransferase 1A) TMT1A METTL7A PRO0066 UNQ1902/PRO4348 Homo sapiens (Human) DNA methylation [GO:0006306]; mRNA methylation [GO:0080009]; odontogenesis [GO:0042476]; osteoblast differentiation [GO:0001649] endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; lipid droplet [GO:0005811]; membrane [GO:0016020]; tertiary granule lumen [GO:1904724] methyltransferase activity [GO:0008168]; mRNA (N6-adenosine)-methyltransferase activity [GO:0001734] 0.0082192 2.141 ELFSNLQEFAGPSGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.98257 0 0 0 0 0 9.47231 0 0 0 10.0272 0 Q9H8J5 MANS1_HUMAN MANSC domain-containing protein 1 (Loss of heterozygosity 12 chromosomal region 3 protein) MANSC1 LOH12CR3 UNQ316/PRO361 Homo sapiens (Human) Golgi apparatus [GO:0005794]; membrane [GO:0016020] 0.80246 0.24048 LSASQNCLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.8096 0 0 0 0 0 0 0 0 0 0 Q9H8K7 PAAT_HUMAN ATPase PAAT (EC 3.6.1.-) (Protein associated with ABC transporters) (PAAT) PAAT C10orf88 Homo sapiens (Human) cytoplasm [GO:0005737]; mitochondrion [GO:0005739] ATP hydrolysis activity [GO:0016887]; identical protein binding [GO:0042802] 0.93034 -1.2389 ILSKNMELMEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3414 0 0 0 0 0 0 0 0 0 Q9H8L6 MMRN2_HUMAN Multimerin-2 (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit) MMRN2 EMILIN3 Homo sapiens (Human) cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903588]; negative regulation of cell migration [GO:0030336]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of epithelial tube formation [GO:1905278]; positive regulation of morphogenesis of an epithelium [GO:1905332] basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; multimerin complex [GO:1990972] 0.56172 0.50899 EEELQYTLEDMRATLTR 0 9.12461 0 0 0 0 0 0 0 10.876 10.5725 10.8629 0 10.6651 0 0 11.1411 0 0 0 0 0 0 0 0 0 0 Q9H8M2 BRD9_HUMAN Bromodomain-containing protein 9 (Rhabdomyosarcoma antigen MU-RMS-40.8) BRD9 UNQ3040/PRO9856 Homo sapiens (Human) chromatin remodeling [GO:0006338]; negative regulation of cell differentiation [GO:0045596]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of stem cell population maintenance [GO:1902459]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; GBAF complex [GO:0140288]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SWI/SNF complex [GO:0016514] lysine-acetylated histone binding [GO:0070577]; nucleic acid binding [GO:0003676] 0.7418 0.32254 HLDDEER 0 0 10.0305 0 0 0 0 9.35012 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H8M5 CNNM2_HUMAN Metal transporter CNNM2 (Ancient conserved domain-containing protein 2) (Cyclin-M2) CNNM2 ACDP2 Homo sapiens (Human) magnesium ion homeostasis [GO:0010960] basolateral plasma membrane [GO:0016323]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; magnesium ion transmembrane transporter activity [GO:0015095] 0.95162 -1.4301 IVQNCGTEKEKNYAK 0 0 0 0 0 9.75317 0 0 0 0 0 0 8.49209 0 0 9.1844 0 0 0 0 0 0 0 0 0 0 0 Q9H8M7 MINY3_HUMAN Ubiquitin carboxyl-terminal hydrolase MINDY-3 (EC 3.4.19.12) (Dermal papilla-derived protein 5) (Deubiquitinating enzyme MINDY-3) (Protein CARP) MINDY3 C10orf97 CARP DERP5 FAM188A MSTP126 My042 Homo sapiens (Human) apoptotic process [GO:0006915]; protein K48-linked deubiquitination [GO:0071108] nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654] cysteine-type deubiquitinase activity [GO:0004843]; K48-linked deubiquitinase activity [GO:1990380] 0.87018 0.039062 ELMELVWGTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.90724 0 0 0 0 0 0 Q9H8P0 PORED_HUMAN Polyprenol reductase (EC 1.3.1.94) (3-oxo-5-alpha-steroid 4-dehydrogenase 3) (EC 1.3.1.22) (Steroid 5-alpha-reductase 2-like) (Steroid 5-alpha-reductase 3) (S5AR 3) (SR type 3) SRD5A3 SRD5A2L Homo sapiens (Human) androgen biosynthetic process [GO:0006702]; dolichol biosynthetic process [GO:0019408]; dolichol metabolic process [GO:0019348]; dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; dolichyl diphosphate biosynthetic process [GO:0006489]; polyprenol catabolic process [GO:0016095] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789] "3-oxo-5-alpha-steroid 4-dehydrogenase activity [GO:0003865]; cholestenone 5-alpha-reductase activity [GO:0047751]; oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [GO:0016628]; polyprenol reductase activity [GO:0102389]" 0.95482 -1.6051 CGEPSRPAACRAFDVPK 0 11.09 11.0639 0 8.93552 0 11.0877 0 0 8.46197 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H8S5 CCNP_HUMAN Cyclin-P (Cyclin N-terminal domain-containing protein 2) CCNP CNTD2 Homo sapiens (Human) mitotic cell cycle phase transition [GO:0044772]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079] centrosome [GO:0005813]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; nucleus [GO:0005634] cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538] 0.91344 -0.75364 AAAALSLAHRLLDGAGSR 9.62569 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H8T0 AKTIP_HUMAN AKT-interacting protein (Ft1) (Fused toes protein homolog) AKTIP FTS Homo sapiens (Human) apoptotic process [GO:0006915]; early endosome to late endosome transport [GO:0045022]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; lysosome organization [GO:0007040]; positive regulation of protein binding [GO:0032092]; positive regulation of protein phosphorylation [GO:0001934]; protein localization to perinuclear region of cytoplasm [GO:1905719]; protein neddylation [GO:0045116]; protein transport [GO:0015031] cytosol [GO:0005829]; FHF complex [GO:0070695]; nucleus [GO:0005634]; plasma membrane [GO:0005886] NEDD8 transferase activity [GO:0019788] 0.85081 0.10829 IDTASPLNPEAAVLYEK 0 10.9819 10.9267 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H8V3 ECT2_HUMAN Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene) ECT2 Homo sapiens (Human) "activation of GTPase activity [GO:0090630]; activation of protein kinase activity [GO:0032147]; bicellular tight junction assembly [GO:0070830]; cell differentiation [GO:0030154]; cell morphogenesis [GO:0000902]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to ionizing radiation [GO:0071479]; intracellular signal transduction [GO:0035556]; mitotic cytokinesis [GO:0000281]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cytokinesis [GO:0032467]; positive regulation of GTPase activity [GO:0043547]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of protein import into nucleus [GO:0042307]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cytokinesis, actomyosin contractile ring assembly [GO:2000431]; regulation of protein kinase activity [GO:0045859]; regulation of small GTPase mediated signal transduction [GO:0051056]" bicellular tight junction [GO:0005923]; cell cortex [GO:0005938]; cell-cell junction [GO:0005911]; centralspindlin complex [GO:0097149]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; protein homodimerization activity [GO:0042803]; small GTPase binding [GO:0031267] 0.96416 -2.2726 QEELIKALK 0 0 0 11.1583 11.3608 11.4922 0 0 0 11.025 11.257 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H8W5 TRI45_HUMAN E3 ubiquitin-protein ligase TRIM45 (EC 2.3.2.27) (RING finger protein 99) TRIM45 RNF99 Homo sapiens (Human) bone development [GO:0060348]; negative regulation of inflammatory response [GO:0050728]; protein K48-linked ubiquitination [GO:0070936] cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; nucleoplasm [GO:0005654] molecular function inhibitor activity [GO:0140678]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.91829 -0.87566 GHPGHPHWSCCGK 0 0 0 0 10.6662 11.0633 13.9661 0 0 14.5278 0 0 9.33865 10.5335 0 0 10.9792 0 0 0 0 0 0 0 0 0 0 Q9H8Y5 ANKZ1_HUMAN tRNA endonuclease ANKZF1 (EC 3.1.-.-) (Ankyrin repeat and zinc finger domain-containing protein 1) (Zinc finger protein 744) ANKZF1 ZNF744 Homo sapiens (Human) cellular response to hydrogen peroxide [GO:0070301]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; rescue of stalled ribosome [GO:0072344]; ubiquitin-dependent ERAD pathway [GO:0030433] cytoplasm [GO:0005737]; membrane [GO:0016020] "catalytic activity, acting on a tRNA [GO:0140101]; metal ion binding [GO:0046872]; RNA endonuclease activity [GO:0004521]" 0.91408 -0.81827 AGDVGVLK 0 0 0 0 0 0 0 0 9.46215 0 0 0 0 0 0 0 0 0 10.109 0 0 0 0 0 0 0 0 Q9H8Y8 GORS2_HUMAN Golgi reassembly-stacking protein 2 (GRS2) (Golgi phosphoprotein 6) (GOLPH6) (Golgi reassembly-stacking protein of 55 kDa) (GRASP55) (p59) GORASP2 GOLPH6 Homo sapiens (Human) cell differentiation [GO:0030154]; establishment of protein localization to plasma membrane [GO:0061951]; Golgi organization [GO:0007030]; organelle assembly [GO:0070925]; organelle organization [GO:0006996]; response to endoplasmic reticulum stress [GO:0034976]; spermatogenesis [GO:0007283] cis-Golgi network [GO:0005801]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020] 0.92448 -0.95134 DLLKANVEKPVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.54212 Q9H900 ZWILC_HUMAN Protein zwilch homolog (hZwilch) ZWILCH Homo sapiens (Human) cell division [GO:0051301]; mitotic spindle assembly checkpoint signaling [GO:0007094]; protein localization to kinetochore [GO:0034501] cytosol [GO:0005829]; kinetochore [GO:0000776]; kinetochore microtubule [GO:0005828]; RZZ complex [GO:1990423] 0.88501 -0.33114 GPLNHLYR 0 0 0 0 0 0 0 10.314 0 0 0 9.08974 0 0 0 0 0 0 9.95187 0 0 0 0 0 0 0 9.65428 Q9H902 REEP1_HUMAN Receptor expression-enhancing protein 1 (Spastic paraplegia 31 protein) REEP1 C2orf23 SPG31 Homo sapiens (Human) endoplasmic reticulum tubular network organization [GO:0071786]; protein insertion into membrane [GO:0051205] cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum tubular network [GO:0071782]; membrane [GO:0016020]; mitochondrial membrane [GO:0031966] microtubule binding [GO:0008017]; olfactory receptor binding [GO:0031849] 0.88528 -0.33508 ASGKHGQPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.74724 0 Q9H903 MTD2L_HUMAN "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial (NADP-dependent methylenetetrahydrofolate dehydrogenase 2-like protein) (MTHFD2-like) [Includes: NAD-dependent methylenetetrahydrofolate dehydrogenase (EC 1.5.1.15) (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]" MTHFD2L Homo sapiens (Human) 10-formyltetrahydrofolate metabolic process [GO:0009256]; folic acid metabolic process [GO:0046655]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999] mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NAD+) activity [GO:0004487]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488] 0.88627 -0.38802 LVGDVDFEAVK 0 0 9.57461 0 0 0 9.57928 0 11.451 9.26529 0 0 0 0 0 0 0 0 0 0 0 9.33438 0 0 0 0 0 Q9H910 JUPI2_HUMAN Jupiter microtubule associated homolog 2 (Hematological and neurological expressed 1-like protein) (HN1-like protein) JPT2 C16orf34 HN1L L11 Homo sapiens (Human) endocytosis involved in viral entry into host cell [GO:0075509]; regulation of calcium-mediated signaling [GO:0050848] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886] 0.56402 0.49841 GSGIFDESTPVQTR 0 0 0 0 0 0 0 0 0 8.82228 0 0 9.48216 0 0 0 0 0 0 8.99203 9.19153 0 0 0 0 0 0 Q9H920 RN121_HUMAN E3 ubiquitin ligase RNF121 (EC 2.3.2.27) (RING finger protein 121) RNF121 Homo sapiens (Human) protein ubiquitination [GO:0016567]; ubiquitin-dependent ERAD pathway [GO:0030433] endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630] 0.92423 -1.0316 KQTCPYCKEK 0 0 8.99726 0 9.24693 0 0 0 0 0 9.79455 0 0 0 0 9.06894 0 0 0 0 0 0 0 0 0 0 0 Q9H930 SP14L_HUMAN Nuclear body protein SP140-like protein SP140L Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]" 0.9688 -3.907 CIQTEDGKWFTPMEFEIK 0 0 0 0 11.2832 10.3231 0 14.7937 0 15.4183 15.4346 8.63416 12.6888 12.7409 0 12.8751 12.8605 0 12.1494 0 8.9134 0 11.5481 0 0 0 0 Q9H936 GHC1_HUMAN Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+) symporter 1) (Solute carrier family 25 member 22) SLC25A22 GC1 Homo sapiens (Human) aspartate transmembrane transport [GO:0015810]; L-glutamate transmembrane transport [GO:0015813]; malate-aspartate shuttle [GO:0043490]; monoatomic ion transport [GO:0006811]; regulation of insulin secretion [GO:0050796] mitochondrial inner membrane [GO:0005743] amino acid:proton symporter activity [GO:0005280]; L-aspartate transmembrane transporter activity [GO:0015183]; L-glutamate transmembrane transporter activity [GO:0005313] 0.95945 -1.7515 GIAGLYK 0 0 0 0 0 0 0 0 0 0 0 0 9.62416 0 9.65252 0 0 9.74364 0 0 0 0 0 0 0 0 0 Q9H939 PPIP2_HUMAN Proline-serine-threonine phosphatase-interacting protein 2 (PEST phosphatase-interacting protein 2) PSTPIP2 Homo sapiens (Human) actin filament polymerization [GO:0030041] actin filament [GO:0005884]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886] actin filament binding [GO:0051015] 0.92621 -0.96239 ACEAFEAQECER 0 0 0 0 0 0 0 0 0 0 0 0 9.95434 10.2312 0 0 10.5704 0 0 0 0 0 10.0996 0 0 12.1131 0 Q9H967 WDR76_HUMAN WD repeat-containing protein 76 WDR76 Homo sapiens (Human) DNA damage response [GO:0006974]; regulation of DNA damage checkpoint [GO:2000001] heterochromatin [GO:0000792]; nucleus [GO:0005634]; site of DNA damage [GO:0090734] DNA binding [GO:0003677]; enzyme binding [GO:0019899] 0.96944 -3.1175 ADSRQRPQMK 0 0 8.96555 0 0 0 9.24141 9.20545 9.39938 0 10.2407 9.37563 9.20063 0 0 12.3921 9.06229 0 0 0 10.6402 0 10.4654 0 10.4249 10.3129 0 Q9H981 ARP8_HUMAN Actin-related protein 8 (hArp8) (INO80 complex subunit N) ACTR8 ARP8 INO80N Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of telomere maintenance in response to DNA damage [GO:1904507]; regulation of cell cycle [GO:0051726]; regulation of chromosome organization [GO:0033044]; regulation of DNA repair [GO:0006282]; regulation of DNA replication [GO:0006275]; regulation of DNA strand elongation [GO:0060382]; regulation of DNA-templated transcription [GO:0006355]; regulation of embryonic development [GO:0045995]; telomere maintenance [GO:0000723] centrosome [GO:0005813]; Ino80 complex [GO:0031011]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524] 0.95517 -1.5856 QEQSAKATADR 0 8.28133 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.538 0 0 0 0 0 0 0 Q9H987 SYP2L_HUMAN Synaptopodin 2-like protein SYNPO2L Homo sapiens (Human) heart morphogenesis [GO:0003007]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of stress fiber assembly [GO:0051496]; sarcomere organization [GO:0045214] actin cytoskeleton [GO:0015629]; nucleus [GO:0005634]; Z disc [GO:0030018] actin binding [GO:0003779] 0.93013 -1.237 KQMFRPGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4092 0 0 0 0 0 0 0 0 0 Q9H992 MARH7_HUMAN E3 ubiquitin-protein ligase MARCHF7 (EC 2.3.2.27) (Axotrophin) (Membrane-associated RING finger protein 7) (Membrane-associated RING-CH protein VII) (MARCH-VII) (RING finger protein 177) (RING-type E3 ubiquitin transferase MARCHF7) MARCHF7 AXOT MARCH7 RNF177 Homo sapiens (Human) "negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of proteasomal protein catabolic process [GO:1901799]; negative regulation of protein autoubiquitination [GO:1905524]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein polyubiquitination [GO:1902916]; protein autoubiquitination [GO:0051865]; protein monoubiquitination [GO:0006513]; protein stabilization [GO:0050821]; regulation of tolerance induction [GO:0002643]" cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886] MDM2/MDM4 family protein binding [GO:0097371]; transferase activity [GO:0016740]; ubiquitin binding [GO:0043130]; ubiquitin conjugating enzyme binding [GO:0031624]; zinc ion binding [GO:0008270] 0.95498 -1.5216 NSLRSNFSSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.25538 0 0 0 0 0 0 Q9H9A6 LRC40_HUMAN Leucine-rich repeat-containing protein 40 LRRC40 Homo sapiens (Human) membrane [GO:0016020] 0.91416 -0.76119 KSGQLNLSGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6511 0 0 0 0 0 0 0 0 0 0 0 0 Q9H9A7 RMI1_HUMAN RecQ-mediated genome instability protein 1 (BLM-associated protein of 75 kDa) (BLAP75) (FAAP75) RMI1 C9orf76 Homo sapiens (Human) DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; glucose homeostasis [GO:0042593]; multicellular organism growth [GO:0035264]; reduction of food intake in response to dietary excess [GO:0002023]; resolution of meiotic recombination intermediates [GO:0000712]; resolution of recombination intermediates [GO:0071139]; response to glucose [GO:0009749] nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RecQ family helicase-topoisomerase III complex [GO:0031422] nucleotide binding [GO:0000166] 0.84843 0.11502 ILNREVVNYVQK 0 0 0 0 0 0 0 0 0 0 0 12.9507 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H9B1 EHMT1_HUMAN Histone-lysine N-methyltransferase EHMT1 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a-like protein 1) (GLP) (GLP1) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Lysine N-methyltransferase 1D) EHMT1 EUHMTASE1 GLP KIAA1876 KMT1D Homo sapiens (Human) chromatin organization [GO:0006325]; DNA methylation [GO:0006306]; facultative heterochromatin formation [GO:0140718]; histone lysine methylation [GO:0034968]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of embryonic development [GO:0045995] chromatin [GO:0000785]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] C2H2 zinc finger domain binding [GO:0070742]; histone H3K27 methyltransferase activity [GO:0046976]; histone H3K9 methyltransferase activity [GO:0046974]; histone H3K9me2 methyltransferase activity [GO:0140947]; methyltransferase activity [GO:0008168]; p53 binding [GO:0002039]; protein-lysine N-methyltransferase activity [GO:0016279]; transcription corepressor binding [GO:0001222]; zinc ion binding [GO:0008270] 0.7284 0.34579 YELMRPSNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1037 0 0 Q9H9B4 SFXN1_HUMAN Sideroflexin-1 SFXN1 Homo sapiens (Human) erythrocyte differentiation [GO:0030218]; iron ion transport [GO:0006826]; L-alanine transport [GO:0015808]; L-serine transport [GO:0015825]; one-carbon metabolic process [GO:0006730]; serine import into mitochondrion [GO:0140300] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] L-alanine transmembrane transporter activity [GO:0015180]; L-serine transmembrane transporter activity [GO:0015194]; monoatomic ion transmembrane transporter activity [GO:0015075]; serine transmembrane transporter activity [GO:0022889] 0.88355 -0.31886 EPRWDQSTFIGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9019 0 0 0 0 0 0 0 0 0 0 Q9H9C1 SPE39_HUMAN Spermatogenesis-defective protein 39 homolog (hSPE-39) (VPS33B-interacting protein in apical-basolateral polarity regulator) (VPS33B-interacting protein in polarity and apical restriction) VIPAS39 C14orf133 SPE39 VIPAR Homo sapiens (Human) cell differentiation [GO:0030154]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; intracellular transport [GO:0046907]; peptidyl-lysine hydroxylation [GO:0017185]; phagosome-lysosome fusion [GO:0090385]; post-translational protein modification [GO:0043687]; spermatogenesis [GO:0007283]; vacuolar transport [GO:0007034] cytoplasm [GO:0005737]; early endosome [GO:0005769]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; recycling endosome [GO:0055037]; vesicle tethering complex [GO:0099023] protein-containing complex binding [GO:0044877] 0.90537 -0.72081 CHDVVIDTYR 0 0 0 0 0 0 0 0 0 0 0 8.98051 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H9D4 ZN408_HUMAN Zinc finger protein 408 (PR domain zinc finger protein 17) ZNF408 PFM14 PRDM17 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96784 -3.6936 ALQLAREPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0724 0 0 0 0 0 0 0 0 0 0 10.3523 0 Q9H9E3 COG4_HUMAN Conserved oligomeric Golgi complex subunit 4 (COG complex subunit 4) (Component of oligomeric Golgi complex 4) COG4 Homo sapiens (Human) "glycosylation [GO:0070085]; Golgi organization [GO:0007030]; Golgi vesicle prefusion complex stabilization [GO:0048213]; protein transport [GO:0015031]; retrograde transport, vesicle recycling within Golgi [GO:0000301]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]" cytosol [GO:0005829]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; trans-Golgi network membrane [GO:0032588] identical protein binding [GO:0042802] 0.88906 -0.42359 AVALDTYEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.4886 0 0 0 0 8.89163 0 0 0 0 0 10.0374 0 Q9H9J2 RM44_HUMAN "Large ribosomal subunit protein mL44 (EC 3.1.26.-) (39S ribosomal protein L44, mitochondrial) (L44mt) (MRP-L44)" MRPL44 Homo sapiens (Human) mitochondrial translation [GO:0032543]; mitochondrial translational elongation [GO:0070125]; rRNA processing [GO:0006364] mitochondrial inner membrane [GO:0005743]; mitochondrial large ribosomal subunit [GO:0005762]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.84386 0.1524 LQENFSLDLLK 0 0 0 0 0 0 10.6274 9.47972 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H9J4 UBP42_HUMAN Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.4.19.12) (Deubiquitinating enzyme 42) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) USP42 Homo sapiens (Human) cell differentiation [GO:0030154]; protein deubiquitination [GO:0016579]; regulation of apoptotic process [GO:0042981]; spermatogenesis [GO:0007283]; ubiquitin-dependent protein catabolic process [GO:0006511] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] cysteine-type deubiquitinase activity [GO:0004843]; cysteine-type endopeptidase activity [GO:0004197] 0.92334 -1.1635 DPGTPATK 0 12.5148 0 12.351 12.4227 12.2386 12.2972 0 0 0 0 12.7744 9.88209 0 0 0 0 11.7493 0 0 8.32396 0 8.32638 0 0 0 0 Q9H9L3 I20L2_HUMAN Interferon-stimulated 20 kDa exonuclease-like 2 (EC 3.1.-.-) ISG20L2 HSD-38 HSD38 Homo sapiens (Human) ribosome biogenesis [GO:0042254] nucleolus [GO:0005730]; nucleus [GO:0005634] 3'-5'-RNA exonuclease activity [GO:0000175]; exonuclease activity [GO:0004527]; RNA binding [GO:0003723] 0.96938 -3.1311 APKLHSEPSKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.537 0 Q9H9L4 KANL2_HUMAN KAT8 regulatory NSL complex subunit 2 (NSL complex protein NSL2) (Non-specific lethal 2 homolog) KANSL2 C12orf41 NSL2 Homo sapiens (Human) chromatin organization [GO:0006325]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of histone H3-K4 methylation [GO:0051571]; regulation of dosage compensation by inactivation of X chromosome [GO:1900095] actin cytoskeleton [GO:0015629]; cytosol [GO:0005829]; histone acetyltransferase complex [GO:0000123]; NSL complex [GO:0044545]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] 0.90819 -0.74313 RLQHLLKEK 0 0 0 0 0 0 0 0 11.7816 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H9P5 UNKL_HUMAN Putative E3 ubiquitin-protein ligase UNKL (EC 2.3.2.-) (RING finger protein unkempt-like) (Zinc finger CCCH domain-containing protein 5-like) UNKL C16orf28 ZC3H5L ZC3HDC5L Homo sapiens (Human) protein ubiquitination [GO:0016567] cytosol [GO:0005829]; nucleus [GO:0005634] metal ion binding [GO:0046872]; transferase activity [GO:0016740] 0.82051 0.21694 QWEESWQQVK 0 0 0 0 0 0 9.434 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H9P8 L2HDH_HUMAN "L-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.2) (Duranin)" L2HGDH C14orf160 Homo sapiens (Human) 2-oxoglutarate metabolic process [GO:0006103]; small molecule metabolic process [GO:0044281] membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] 2-hydroxyglutarate dehydrogenase activity [GO:0047545] 0.63086 0.40503 LIQQEDIK 0 0 0 0 0 0 10.8356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H9Q2 CSN7B_HUMAN COP9 signalosome complex subunit 7b (SGN7b) (Signalosome subunit 7b) (JAB1-containing signalosome subunit 7b) COPS7B CSN7B Homo sapiens (Human) COP9 signalosome assembly [GO:0010387]; protein deneddylation [GO:0000338]; protein neddylation [GO:0045116]; regulation of protein neddylation [GO:2000434] COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.95099 -1.4004 ENHNRTQQQVEAEVTNIKK 0 0 0 0 0 0 0 0 9.6961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9H9R9 DBND1_HUMAN Dysbindin domain-containing protein 1 DBNDD1 Homo sapiens (Human) negative regulation of protein kinase activity [GO:0006469] cytoplasm [GO:0005737] 0.95293 -1.4724 AGYLRSPSWTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.72853 9.35905 Q9H9T3 ELP3_HUMAN Elongator complex protein 3 (hELP3) (EC 2.3.1.-) (tRNA uridine(34) acetyltransferase) ELP3 Homo sapiens (Human) central nervous system development [GO:0007417]; neuron migration [GO:0001764]; positive regulation of cell migration [GO:0030335]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation [GO:0002926]; tRNA wobble uridine modification [GO:0002098] cytoplasm [GO:0005737]; cytosol [GO:0005829]; elongator holoenzyme complex [GO:0033588]; nucleolus [GO:0005730]; nucleus [GO:0005634] "4 iron, 4 sulfur cluster binding [GO:0051539]; acetyltransferase activity [GO:0016407]; metal ion binding [GO:0046872]; phosphorylase kinase regulator activity [GO:0008607]; tRNA binding [GO:0000049]; tRNA uridine(34) acetyltransferase activity [GO:0106261]" 0.89861 -0.66518 AVCESFHLAK 0 0 0 7.75154 0 0 0 0 0 0 14.0406 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.63457 0 Q9H9Y6 RPA2_HUMAN DNA-directed RNA polymerase I subunit RPA2 (RNA polymerase I subunit 2) (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (RPA135) POLR1B Homo sapiens (Human) embryo implantation [GO:0007566]; neural crest formation [GO:0014029]; nucleologenesis [GO:0017126]; rRNA transcription [GO:0009303]; transcription by RNA polymerase I [GO:0006360] chromosome [GO:0005694]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; RNA polymerase I complex [GO:0005736] DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; metal ion binding [GO:0046872]; ribonucleoside binding [GO:0032549] 0.88695 -0.34779 DLAPGIADSLR 0 0 0 0 0 0 8.80858 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.5477 0 Q9H9Z2 LN28A_HUMAN Protein lin-28 homolog A (Lin-28A) (Zinc finger CCHC domain-containing protein 1) LIN28A CSDD1 LIN28 ZCCHC1 Homo sapiens (Human) cellular response to glucose stimulus [GO:0071333]; germ cell development [GO:0007281]; miRNA catabolic process [GO:0010587]; negative regulation of glial cell differentiation [GO:0045686]; negative regulation of pre-miRNA processing [GO:2000632]; negative regulation of translation [GO:0017148]; positive regulation of cell proliferation involved in kidney development [GO:1901724]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of TOR signaling [GO:0032008]; pre-miRNA processing [GO:0031054]; RNA 3' uridylation [GO:0071076]; RNA 3'-end processing [GO:0031123]; stem cell differentiation [GO:0048863]; stem cell population maintenance [GO:0019827] cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleus [GO:0005634]; P-body [GO:0000932]; polysome [GO:0005844]; ribonucleoprotein complex [GO:1990904]; rough endoplasmic reticulum [GO:0005791] G-quadruplex RNA binding [GO:0002151]; miRNA binding [GO:0035198]; polysome binding [GO:1905538]; pre-miRNA binding [GO:0070883]; protein-RNA adaptor activity [GO:0140517]; RNA binding [GO:0003723]; sequence-specific mRNA binding [GO:1990825]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270] 0.87054 0.042814 GSVSNQQFAGGCAK 8.98704 8.87092 8.54782 0 0 0 0 0 8.55827 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HA38 ZMAT3_HUMAN Zinc finger matrin-type protein 3 (Zinc finger protein WIG-1) (p53-activated gene 608 protein) ZMAT3 PAG608 WIG1 Homo sapiens (Human) apoptotic process [GO:0006915]; DNA damage response [GO:0006974]; protein transport [GO:0015031] nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] RNA binding [GO:0003723]; zinc ion binding [GO:0008270] 0.93955 -1.3244 RNMYTVQNNSAGPYFNPRSR 0 10.64 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HA64 KT3K_HUMAN Ketosamine-3-kinase (EC 2.7.1.172) (Fructosamine-3-kinase-related protein) (FN3K-RP) (FN3K-related protein) (Protein-psicosamine 3-kinase FN3KRP) (EC 2.7.1.-) FN3KRP Homo sapiens (Human) phosphorylation [GO:0016310]; post-translational protein modification [GO:0043687] cytosol [GO:0005829] ATP binding [GO:0005524]; kinase activity [GO:0016301]; protein-ribulosamine 3-kinase activity [GO:0102193] 0.84883 0.17174 SYDTDQGR 0 0 0 0 0 0 0 0 0 10.5347 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HA82 CERS4_HUMAN Ceramide synthase 4 (CerS4) (EC 2.3.1.-) (LAG1 longevity assurance homolog 4) (Sphingosine N-acyltransferase CERS4) (EC 2.3.1.24) CERS4 LASS4 Homo sapiens (Human) ceramide biosynthetic process [GO:0046513]; sphingolipid biosynthetic process [GO:0030148] endoplasmic reticulum membrane [GO:0005789] DNA binding [GO:0003677]; sphingosine N-acyltransferase activity [GO:0050291] 0.92436 -1.1714 KFCEASWR 0 0 0 0 0 0 9.94303 9.88548 10.0664 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HA90 EFCC1_HUMAN EF-hand and coiled-coil domain-containing protein 1 (Coiled-coil domain-containing protein 48) EFCC1 C3orf73 CCDC48 Homo sapiens (Human) calcium ion binding [GO:0005509] 0.93964 -1.3252 KTPAAEAKTLLAR 0 9.78341 9.66238 9.60857 9.40678 0 10.9172 11.1506 0 0 10.6785 0 11.5509 11.5404 11.5152 0 0 9.87825 0 0 9.98698 0 0 9.17078 0 0 0 Q9HA92 RSAD1_HUMAN "Radical S-adenosyl methionine domain-containing protein 1, mitochondrial (Putative heme chaperone)" RSAD1 Homo sapiens (Human) porphyrin-containing compound biosynthetic process [GO:0006779] cytoplasm [GO:0005737]; mitochondrion [GO:0005739] "4 iron, 4 sulfur cluster binding [GO:0051539]; coproporphyrinogen oxidase activity [GO:0004109]; heme binding [GO:0020037]; metal ion binding [GO:0046872]" 0.94762 -1.3545 ALPGARARGWAAAAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5997 0 0 0 0 0 0 0 0 0 0 0 Q9HAC7 SUCHY_HUMAN Succinate--hydroxymethylglutarate CoA-transferase (EC 2.8.3.13) (Dermal papilla-derived protein 13) (SuccinylCoA:glutarate-CoA transferase) SUGCT C7orf10 DERP13 Homo sapiens (Human) mitochondrion [GO:0005739] succinate-hydroxymethylglutarate CoA-transferase activity [GO:0047369] 0.96755 -2.7877 EVLRYDDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.9845 0 0 Q9HAC8 UBTD1_HUMAN Ubiquitin domain-containing protein 1 UBTD1 Homo sapiens (Human) 0.95509 -1.5681 TRLQETK 0 0 0 0 0 0 0 0 0 0 0 12.6568 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HAD4 WDR41_HUMAN WD repeat-containing protein 41 WDR41 MSTP048 Homo sapiens (Human) autophagy [GO:0006914]; negative regulation of exocytosis [GO:0045920]; negative regulation of immune response [GO:0050777]; positive regulation of GTPase activity [GO:0043547]; regulation of autophagy [GO:0010506] cytoplasm [GO:0005737]; guanyl-nucleotide exchange factor complex [GO:0032045]; lysosomal membrane [GO:0005765] 0.94901 -1.3757 ISCFQSTVK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.05134 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HAE3 CLXN_HUMAN Calaxin (EF-hand calcium-binding domain-containing protein 1) CLXN EFCAB1 Homo sapiens (Human) cilium movement [GO:0003341]; outer dynein arm assembly [GO:0036158]; regulation of cilium movement [GO:0003352]; regulation of flagellated sperm motility [GO:1901317] cilium [GO:0005929]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856] calcium ion binding [GO:0005509] 0.88856 -0.4256 KMDHDHDGK 0 0 0 0 11.1406 0 0 0 0 0 0 0 0 0 0 11.6529 0 0 0 0 0 0 0 0 8.44787 0 0 Q9HAH1 ZN556_HUMAN Zinc finger protein 556 ZNF556 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.95927 -1.8632 CEKCGKAFSCPK 9.99407 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.12531 0 0 0 0 0 Q9HAH7 FBRS_HUMAN Probable fibrosin-1 FBRS FBS FBS1 Homo sapiens (Human) 0.93148 -1.2697 ESVRVKEER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.948 0 0 0 0 0 0 0 0 0 0 0 0 Q9HAQ2 KIF9_HUMAN Kinesin-like protein KIF9 KIF9 Homo sapiens (Human) extracellular matrix disassembly [GO:0022617]; microtubule-based movement [GO:0007018]; organelle disassembly [GO:1903008]; regulation of flagellated sperm motility [GO:1901317]; regulation of podosome assembly [GO:0071801] cytoplasm [GO:0005737]; kinesin complex [GO:0005871]; microtubule [GO:0005874]; podosome [GO:0002102]; sperm flagellum [GO:0036126]; vesicle [GO:0031982] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777] 0.7163 0.36543 IFKENKSILNER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.66592 0 0 0 0 0 0 0 0 0 0 Q9HAR2 AGRL3_HUMAN Adhesion G protein-coupled receptor L3 (Calcium-independent alpha-latrotoxin receptor 3) (CIRL-3) (Latrophilin-3) (Lectomedin-3) ADGRL3 KIAA0768 LEC3 LPHN3 Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; brain development [GO:0007420]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; G protein-coupled receptor signaling pathway [GO:0007186]; neuron migration [GO:0001764]; synapse assembly [GO:0007416] axon [GO:0030424]; cell-cell junction [GO:0005911]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; G protein-coupled receptor activity [GO:0004930] 0.96169 -2.0737 DPLQASDKIYYMPWTPYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5021 0 0 Q9HAS0 NJMU_HUMAN Protein Njmu-R1 C17orf75 Homo sapiens (Human) intracellular protein transport [GO:0006886]; vesicle tethering to Golgi [GO:0099041] cytoplasmic vesicle [GO:0031410]; trans-Golgi network [GO:0005802] 0.84772 0.15775 NNMNCEAR 0 0 0 0 0 0 0 0 0 0 0 8.8849 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HAS3 S28A3_HUMAN Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (CNT 3) (hCNT3) SLC28A3 CNT3 Homo sapiens (Human) nucleoside transmembrane transport [GO:1901642]; purine nucleobase transmembrane transport [GO:1904823]; purine nucleoside transmembrane transport [GO:0015860]; pyrimidine nucleoside transport [GO:0015864]; pyrimidine-containing compound transmembrane transport [GO:0072531]; uridine transport [GO:0015862]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] brush border membrane [GO:0031526]; endoplasmic reticulum membrane [GO:0005789]; plasma membrane [GO:0005886] nucleoside:sodium symporter activity [GO:0005415]; purine nucleobase transmembrane transporter activity [GO:0005345]; purine-specific nucleoside:sodium symporter activity [GO:0015390]; pyrimidine- and adenosine-specific:sodium symporter activity [GO:0015389]; uridine transmembrane transporter activity [GO:0015213] 0.73171 0.33738 YDTVCGFCR 9.24432 9.0717 0 0 0 0 8.78803 0 0 9.48022 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HAT0 ROP1A_HUMAN Ropporin-1A (Cancer/testis antigen 91) (CT91) (Rhophilin-associated protein 1A) ROPN1 ROPN1A Homo sapiens (Human) cilium organization [GO:0044782]; flagellated sperm motility [GO:0030317]; protein localization to cilium [GO:0061512]; regulation of protein phosphorylation [GO:0001932]; sperm capacitation [GO:0048240] cytoplasm [GO:0005737]; motile cilium [GO:0031514]; nucleus [GO:0005634] identical protein binding [GO:0042802] 0.77207 0.27168 AELTPELLK 0 0 0 9.71339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HAT1 LMA1L_HUMAN Protein ERGIC-53-like (ERGIC53-like protein) (Lectin mannose-binding 1-like) (LMAN1-like protein) LMAN1L ERGL UNQ2784/PRO7174 Homo sapiens (Human) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888] collagen-containing extracellular matrix [GO:0062023]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; Golgi membrane [GO:0000139] mannose binding [GO:0005537] 0.84896 0.15444 ITYWGQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.8839 0 0 0 0 0 0 0 0 Q9HAU0 PKHA5_HUMAN Pleckstrin homology domain-containing family A member 5 (PH domain-containing family A member 5) (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2) PLEKHA5 KIAA1686 PEPP2 Homo sapiens (Human) reproductive system development [GO:0061458] cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; postsynaptic density [GO:0014069] "phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]" 0.97015 -5.1537 AQIQKELWR 0 0 0 0 8.92618 0 0 0 9.5671 0 9.15947 8.95939 0 0 0 0 0 8.99904 0 0 0 0 0 0 0 0 10.2022 Q9HAU4 SMUF2_HUMAN E3 ubiquitin-protein ligase SMURF2 (hSMURF2) (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase SMURF2) (SMAD ubiquitination regulatory factor 2) (SMAD-specific E3 ubiquitin-protein ligase 2) SMURF2 Homo sapiens (Human) "negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of trophoblast cell migration [GO:1901165]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent SMAD protein catabolic process [GO:0030579]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane raft [GO:0045121]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ubiquitin ligase complex [GO:0000151] identical protein binding [GO:0042802]; SMAD binding [GO:0046332]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.35941 0.74963 EEIFEESYRQVMK 0 0 0 0 0 0 0 0 9.32897 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HAU5 RENT2_HUMAN Regulator of nonsense transcripts 2 (Up-frameshift suppressor 2 homolog) (hUpf2) UPF2 KIAA1408 RENT2 Homo sapiens (Human) "animal organ regeneration [GO:0031100]; liver development [GO:0001889]; mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]" cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; exon-exon junction complex [GO:0035145]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; polysome [GO:0005844] molecular adaptor activity [GO:0060090]; RNA binding [GO:0003723]; telomeric DNA binding [GO:0042162] 0.96915 -6.0693 ALFIVPR 10.1393 9.82774 0 0 0 0 0 0 0 0 0 10.6782 0 0 0 0 0 0 0 0 0 10.3718 0 0 0 0 0 Q9HAU8 RNPL1_HUMAN Aminopeptidase RNPEPL1 (EC 3.4.11.-) (Arginyl aminopeptidase-like 1) (Methionyl aminopeptidase) (EC 3.4.11.18) RNPEPL1 Homo sapiens (Human) proteolysis [GO:0006508] metalloaminopeptidase activity [GO:0070006]; zinc ion binding [GO:0008270] 0.89669 -0.53934 RFLESQMSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.7144 0 0 0 0 0 0 0 0 Q9HAV0 GBB4_HUMAN Guanine nucleotide-binding protein subunit beta-4 (Transducin beta chain 4) GNB4 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; substantia nigra development [GO:0021762] cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; heterotrimeric G-protein complex [GO:0005834]; lysosomal membrane [GO:0005765] protein-containing complex binding [GO:0044877]; signaling receptor complex adaptor activity [GO:0030159] 0.9187 -0.87884 LLLAGYDDFNCNVWDTLKGDR 0 0 0 10.4157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HAV4 XPO5_HUMAN Exportin-5 (Exp5) (Ran-binding protein 21) XPO5 KIAA1291 RANBP21 Homo sapiens (Human) miRNA metabolic process [GO:0010586]; positive regulation of post-transcriptional gene silencing by RNA [GO:1900370]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; RNA export from nucleus [GO:0006405] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RISC complex [GO:0016442]; RNA nuclear export complex [GO:0042565] mRNA binding [GO:0003729]; nuclear export signal receptor activity [GO:0005049]; pre-miRNA binding [GO:0070883]; RISC complex binding [GO:1905172]; RNA binding [GO:0003723]; small GTPase binding [GO:0031267]; tRNA binding [GO:0000049] 0.96772 -2.8556 APRTRAVR 10.5558 10.5507 10.6501 9.84194 9.96665 11.2972 10.5755 10.4213 10.5189 0 16.2303 0 10.332 10.5158 10.2608 0 0 0 0 11.3881 11.3485 11.1997 11.1033 11.1545 0 0 0 Q9HAV7 GRPE1_HUMAN "GrpE protein homolog 1, mitochondrial (HMGE) (Mt-GrpE#1)" GRPEL1 GREPEL1 Homo sapiens (Human) intracellular protein transport [GO:0006886]; protein folding [GO:0006457]; protein import into mitochondrial matrix [GO:0030150] "mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; PAM complex, Tim23 associated import motor [GO:0001405]; TIM23 mitochondrial import inner membrane translocase complex [GO:0005744]" adenyl-nucleotide exchange factor activity [GO:0000774]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein-folding chaperone binding [GO:0051087]; unfolded protein binding [GO:0051082] 0.7301 0.33152 ADPPATEK 0 0 0 0 0 0 0 0 0 9.23419 9.31157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HAW4 CLSPN_HUMAN Claspin (hClaspin) CLSPN Homo sapiens (Human) activation of protein kinase activity [GO:0032147]; DNA damage checkpoint signaling [GO:0000077]; DNA repair [GO:0006281]; DNA replication checkpoint signaling [GO:0000076]; mitotic DNA replication checkpoint signaling [GO:0033314]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; peptidyl-serine phosphorylation [GO:0018105] Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] anaphase-promoting complex binding [GO:0010997]; DNA secondary structure binding [GO:0000217] 0.96639 -2.3545 IEREQWLR 0 0 0 0 0 0 0 0 0 0 10.4392 0 0 0 0 0 9.26496 0 0 11.827 0 0 0 0 13.3509 0 0 Q9HAZ1 CLK4_HUMAN Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4) CLK4 Homo sapiens (Human) peptidyl-tyrosine phosphorylation [GO:0018108]; protein autophosphorylation [GO:0046777]; regulation of RNA splicing [GO:0043484] nucleus [GO:0005634] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein tyrosine kinase activity [GO:0004713] 0.96212 -2.4774 SLNERDYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.93075 0 0 0 0 0 0 0 0 0 0 0 0 Q9HB07 MYG1_HUMAN MYG1 exonuclease (EC 3.1.-.-) MYG1 C12orf10 Homo sapiens (Human) locomotory exploration behavior [GO:0035641] cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] nuclease activity [GO:0004518] 0.86429 0.082287 AMDLVQEEFLQR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.52121 0 9.76671 0 9.66318 0 9.61798 0 0 8.49961 9.71354 0 0 0 Q9HB09 B2L12_HUMAN Bcl-2-like protein 12 (Bcl2-L-12) (Bcl-2-related proline-rich protein) BCL2L12 BPR Homo sapiens (Human) apoptotic process [GO:0006915]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of extrinsic apoptotic signaling pathway [GO:2001236] membrane [GO:0016020]; nucleus [GO:0005634] 0.88371 -0.31774 VQWRRPQVEWR 0 0 0 0 0 9.3028 0 8.75268 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HB15 KCNKC_HUMAN Potassium channel subfamily K member 12 (Tandem pore domain halothane-inhibited potassium channel 2) (THIK-2) KCNK12 Homo sapiens (Human) potassium ion transmembrane transport [GO:0071805]; regulation of monoatomic ion transmembrane transport [GO:0034765]; stabilization of membrane potential [GO:0030322] membrane [GO:0016020] potassium ion leak channel activity [GO:0022841]; voltage-gated monoatomic ion channel activity [GO:0005244] 0.80009 0.23976 QLSETANGYPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5879 Q9HB19 PKHA2_HUMAN Pleckstrin homology domain-containing family A member 2 (PH domain-containing family A member 2) (Tandem PH domain-containing protein 2) (TAPP-2) PLEKHA2 TAPP2 Homo sapiens (Human) positive regulation of cell-matrix adhesion [GO:0001954] cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] "fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; lipid binding [GO:0008289]; PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]" 0.96139 -2.5603 SEPQHPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.3818 0 0 0 0 0 0 0 0 Q9HB55 CP343_HUMAN Cytochrome P450 3A43 (EC 1.14.14.1) CYP3A43 Homo sapiens (Human) oxidative demethylation [GO:0070989] endoplasmic reticulum membrane [GO:0005789] aromatase activity [GO:0070330]; estrogen 16-alpha-hydroxylase activity [GO:0101020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497] 0.97005 -5.2903 ALQNFSFKPCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.9368 0 0 0 0 0 0 0 8.21169 0 Q9HB71 CYBP_HUMAN Calcyclin-binding protein (CacyBP) (hCacyBP) (S100A6-binding protein) (Siah-interacting protein) CACYBP S100A6BP SIP PNAS-107 Homo sapiens (Human) cellular response to leukemia inhibitory factor [GO:1990830]; heart development [GO:0007507] beta-catenin destruction complex [GO:0030877]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nuclear envelope lumen [GO:0005641]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005] protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; tubulin binding [GO:0015631]; ubiquitin protein ligase binding [GO:0031625] 0.88238 -0.084001 IETEIKNKMQQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5319 0 0 0 10.4835 0 9.92861 0 0 10.9433 0 0 Q9HB75 PIDD1_HUMAN p53-induced death domain-containing protein 1 (EC 3.4.21.-) (Leucine-rich repeat and death domain-containing protein) [Cleaved into: PIDD-N; PIDD-C; PIDD-CC] PIDD1 LRDD PIDD Homo sapiens (Human) "activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; DNA damage response [GO:0006974]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; negative regulation of apoptotic process [GO:0043066]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein autoprocessing [GO:0016540]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; signal transduction [GO:0007165]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; endopeptidase complex [GO:1905369]; Golgi apparatus [GO:0005794]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] death receptor binding [GO:0005123]; endopeptidase activity [GO:0004175] 0.96934 -3.394 EVQRIRHEFR 0 0 0 0 0 0 0 0 0 0 0 8.73139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HB89 NMUR1_HUMAN Neuromedin-U receptor 1 (NMU-R1) (G-protein coupled receptor 66) (G-protein coupled receptor FM-3) NMUR1 GPR66 Homo sapiens (Human) activation of phospholipase C activity [GO:0007202]; calcium ion transport [GO:0006816]; calcium-mediated signaling [GO:0019722]; chloride transport [GO:0006821]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate-mediated signaling [GO:0048016]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; smooth muscle contraction [GO:0006939] membrane [GO:0016020]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; neuromedin U binding [GO:0042924]; neuromedin U receptor activity [GO:0001607]; neuropeptide receptor activity [GO:0008188] 0.63104 0.40558 ETFQEALCLGACCHR 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5303 11.3815 0 0 0 0 0 0 0 0 0 0 0 11.5272 Q9HB96 FANCE_HUMAN Fanconi anemia group E protein (Protein FACE) FANCE FACE Homo sapiens (Human) interstrand cross-link repair [GO:0036297]; protein monoubiquitination [GO:0006513] centrosome [GO:0005813]; chromatin [GO:0000785]; chromosome [GO:0005694]; Fanconi anaemia nuclear complex [GO:0043240]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.84776 0.15662 SLESLADGGSASPIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.34087 0 Q9HBB8 CDHR5_HUMAN Cadherin-related family member 5 (Mu-protocadherin) (Mucin and cadherin-like protein) (Mucin-like protocadherin) (MLPCDH) CDHR5 MUCDHL MUPCDH UNQ2781/PRO7168 Homo sapiens (Human) cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intermicrovillar adhesion [GO:0090675]; regulation of microvillus length [GO:0032532] apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; clathrin-coated pit [GO:0005905]; extracellular exosome [GO:0070062]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886] beta-catenin binding [GO:0008013]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839] 0.54478 0.57645 AGGSPTAVR 0 0 0 0 0 0 0 0 0 9.44483 0 0 0 0 0 0 0 0 9.79687 0 0 0 0 0 0 0 0 Q9HBE1 PATZ1_HUMAN "POZ-, AT hook-, and zinc finger-containing protein 1 (BTB/POZ domain zinc finger transcription factor) (Protein kinase A RI subunit alpha-associated protein) (Zinc finger and BTB domain-containing protein 19) (Zinc finger protein 278) (Zinc finger sarcoma gene protein)" PATZ1 PATZ RIAZ ZBTB19 ZNF278 ZSG Homo sapiens (Human) male gonad development [GO:0008584]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cytokine production [GO:0001817]; regulation of DNA-templated transcription [GO:0006355]; regulation of immune system process [GO:0002682]; spermatogenesis [GO:0007283]; T cell differentiation [GO:0030217] male germ cell nucleus [GO:0001673]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; ubiquitin protein ligase binding [GO:0031625] 0.75889 0.3023 KHSEGPSNFCSICNR 0 0 0 0 0 0 9.93748 10.2737 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.89615 0 0 0 Q9HBE4 IL21_HUMAN Interleukin-21 (IL-21) (Za11) IL21 Homo sapiens (Human) cell maturation [GO:0048469]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; germinal center B cell differentiation [GO:0002314]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production [GO:0001819]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of type II interferon production [GO:0032729]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; signal transduction [GO:0007165]; T follicular helper cell differentiation [GO:0061470]; tyrosine phosphorylation of STAT protein [GO:0007260] extracellular region [GO:0005576]; extracellular space [GO:0005615] cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; interleukin-2 receptor binding [GO:0005134] 0.91498 -0.78121 LTCPSCDSYEKKPPK 0 0 0 0 0 0 0 0 0 0 0 0 10.9126 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HBF4 ZFYV1_HUMAN Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (SR3) (Tandem FYVE fingers-1) ZFYVE1 DFCP1 KIAA1589 TAFF1 ZNFN2A1 PP10436 Homo sapiens (Human) cellular response to starvation [GO:0009267]; lipid droplet formation [GO:0140042]; macroautophagy [GO:0016236]; positive regulation by host of viral genome replication [GO:0044829] autophagosome [GO:0005776]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extrinsic component of omegasome membrane [GO:0097629]; Golgi apparatus [GO:0005794]; Golgi stack [GO:0005795]; lipid droplet [GO:0005811]; mitochondria-associated endoplasmic reticulum membrane [GO:0044233]; mitochondrion [GO:0005739]; omegasome [GO:1990462]; perinuclear region of cytoplasm [GO:0048471]; phagophore assembly site [GO:0000407] "1-phosphatidylinositol binding [GO:0005545]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; zinc ion binding [GO:0008270]" 0.84437 0.15262 VCFNCNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.94075 0 0 0 0 Q9HBG4 VPP4_HUMAN V-type proton ATPase 116 kDa subunit a 4 (V-ATPase 116 kDa isoform a 4) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 4) (Vacuolar proton translocating ATPase 116 kDa subunit a kidney isoform) ATP6V0A4 ATP6N1B ATP6N2 Homo sapiens (Human) intracellular pH reduction [GO:0051452]; ossification [GO:0001503]; proton transmembrane transport [GO:1902600]; regulation of pH [GO:0006885]; renal tubular secretion [GO:0097254]; sensory perception of sound [GO:0007605]; synaptic vesicle lumen acidification [GO:0097401]; vacuolar acidification [GO:0007035] "apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; lysosomal membrane [GO:0005765]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; proton-transporting V-type ATPase complex [GO:0033176]; synaptic vesicle membrane [GO:0030672]; vacuolar proton-transporting V-type ATPase complex [GO:0016471]; vacuolar proton-transporting V-type ATPase, V0 domain [GO:0000220]" "ATPase binding [GO:0051117]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]" 0.91985 -0.9128 FLEDEMQNEIVVQLLEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.53986 0 0 0 0 0 0 0 0 0 0 0 0 Q9HBG6 IF122_HUMAN Intraflagellar transport protein 122 homolog (WD repeat-containing protein 10) (WD repeat-containing protein 140) IFT122 SPG WDR10 WDR140 Homo sapiens (Human) camera-type eye morphogenesis [GO:0048593]; cilium assembly [GO:0060271]; embryonic body morphogenesis [GO:0010172]; embryonic heart tube development [GO:0035050]; intraciliary retrograde transport [GO:0035721]; intraciliary transport [GO:0042073]; limb development [GO:0060173]; negative regulation of smoothened signaling pathway [GO:0045879]; neural tube closure [GO:0001843]; non-motile cilium assembly [GO:1905515]; protein localization to cilium [GO:0061512] ciliary basal body [GO:0036064]; ciliary tip [GO:0097542]; cilium [GO:0005929]; cytoplasm [GO:0005737]; intraciliary transport particle A [GO:0030991]; membrane [GO:0016020]; non-motile cilium [GO:0097730]; photoreceptor connecting cilium [GO:0032391] 0.88355 -0.32869 EGLLVGLK 0 0 0 0 8.71699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.93174 8.70169 8.67811 0 10.0276 0 Q9HBH1 DEFM_HUMAN "Peptide deformylase, mitochondrial (EC 3.5.1.88) (Polypeptide deformylase)" PDF PDF1A Homo sapiens (Human) co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; peptidyl-methionine modification [GO:0018206]; positive regulation of cell population proliferation [GO:0008284]; translation [GO:0006412] mitochondrion [GO:0005739] metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586] 0.9188 -0.88872 IIQHEMDHLQGCLFIDKMDSR 0 0 0 9.7061 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HBH5 RDH14_HUMAN Retinol dehydrogenase 14 (EC 1.1.1.300) (Alcohol dehydrogenase PAN2) (Short chain dehydrogenase/reductase family 7C member 4) RDH14 PAN2 SDR7C4 UNQ529/PRO1072 Homo sapiens (Human) osteoblast differentiation [GO:0001649] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 11-cis-retinol dehydrogenase activity [GO:0102354]; NADP-retinol dehydrogenase activity [GO:0052650] 0.88565 -0.38696 AEEAAGQLR 0 0 0 0 0 0 0 0 0 0 0 0 9.21133 0 0 0 0 10.4141 0 0 0 0 0 0 0 0 0 Q9HBH7 BEX1_HUMAN Protein BEX1 (Brain-expressed X-linked protein 1) BEX1 Homo sapiens (Human) cell differentiation [GO:0030154]; nervous system development [GO:0007399]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription by RNA polymerase II [GO:0045944]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; signaling receptor binding [GO:0005102] 0.96776 -2.9367 GEPLALPLDAGEYCVPR 0 9.12272 0 0 0 0 0 0 10.0139 0 9.18992 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HBH9 MKNK2_HUMAN MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (MAPK signal-integrating kinase 2) (Mnk2) MKNK2 GPRK7 MNK2 Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; cellular response to arsenic-containing substance [GO:0071243]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; hemopoiesis [GO:0030097]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of translation [GO:0006417] cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605] ATP binding [GO:0005524]; calcium-dependent protein serine/threonine kinase activity [GO:0009931]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; metal ion binding [GO:0046872]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.95976 -1.933 CGSDCGWDR 10.9017 0 0 0 0 0 10.2058 0 0 9.98171 0 0 0 0 11.2081 0 0 0 0 0 0 0 0 0 10.2501 0 0 Q9HBI1 PARVB_HUMAN Beta-parvin (Affixin) PARVB CGI-56 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; cell projection assembly [GO:0030031]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of cell polarity regulating cell shape [GO:0071963]; lamellipodium assembly [GO:0030032]; substrate adhesion-dependent cell spreading [GO:0034446] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886]; Z disc [GO:0030018] actin binding [GO:0003779] 0.95861 -1.8664 SLITFVNKHLNK 0 0 0 9.83161 0 0 11.1859 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HBI5 CEP15_HUMAN Centrosomal protein 15 kDa CEP15 C3orf14 HT021 Homo sapiens (Human) 0.82983 0.21005 LGDQHTEK 0 0 0 0 0 0 0 0 0 0 0 0 9.44684 9.86158 0 0 10.5704 0 0 0 0 0 0 0 0 0 0 Q9HBJ7 UBP29_HUMAN Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.4.19.12) (Deubiquitinating enzyme 29) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) USP29 Homo sapiens (Human) defense response to virus [GO:0051607]; G1/S transition of mitotic cell cycle [GO:0000082]; innate immune response [GO:0045087]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein stabilization [GO:0050821]; ubiquitin-dependent protein catabolic process [GO:0006511] cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] cysteine-type deubiquitinase activity [GO:0004843]; cysteine-type endopeptidase activity [GO:0004197] 0.6973 0.37543 SCVARHTFSRLSR 9.29421 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HBL0 TENS1_HUMAN Tensin-1 (EC 3.1.3.-) TNS1 TNS Homo sapiens (Human) fibroblast migration [GO:0010761] cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925] actin binding [GO:0003779]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; RNA binding [GO:0003723] 0.95933 -1.7076 QSHPLTQSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0902 9.84991 10.3773 0 9.9407 0 0 0 9.34287 0 0 0 Q9HBL6 LRTM1_HUMAN Leucine-rich repeat and transmembrane domain-containing protein 1 LRTM1 HT017 Homo sapiens (Human) axon guidance [GO:0007411]; negative chemotaxis [GO:0050919] membrane [GO:0016020] heparin binding [GO:0008201]; Roundabout binding [GO:0048495] 0.87778 -0.0047299 LFHSLPQLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.62514 9.3285 9.4845 9.13 0 0 0 0 0 0 0 0 0 Q9HBL8 NMRL1_HUMAN NmrA-like family domain-containing protein 1 NMRAL1 HSCARG Homo sapiens (Human) cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] identical protein binding [GO:0042802] 0.89907 -0.57585 DIGVPMTSVR 0 0 0 0 0 0 0 0 0 0 9.82279 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HBM0 VEZA_HUMAN Vezatin VEZT Homo sapiens (Human) cell-cell adhesion [GO:0098609] acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; stereocilia ankle link complex [GO:0002142]; stereocilium membrane [GO:0060171] myosin binding [GO:0017022] 0.96951 -4.0609 RSYEFYR 0 0 0 0 0 0 0 0 0 0 0 9.10826 0 0 0 0 0 0 0 0 0 0 0 0 10.519 0 0 Q9HBM1 SPC25_HUMAN Kinetochore protein Spc25 (hSpc25) SPC25 SPBC25 AD024 Homo sapiens (Human) attachment of spindle microtubules to kinetochore [GO:0008608]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; mitotic spindle assembly checkpoint signaling [GO:0007094]; mitotic spindle organization [GO:0007052] cytosol [GO:0005829]; kinetochore [GO:0000776]; Ndc80 complex [GO:0031262]; nucleus [GO:0005634] 0.42457 0.66799 KETISTANK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2046 0 0 0 0 0 0 0 0 0 0 0 0 Q9HBM6 TAF9B_HUMAN Transcription initiation factor TFIID subunit 9B (Neuronal cell death-related protein 7) (DN-7) (Transcription initiation factor TFIID subunit 9-like) (Transcription-associated factor TAFII31L) TAF9B TAF9L Homo sapiens (Human) DNA-templated transcription initiation [GO:0006352]; negative regulation of apoptotic process [GO:0043066]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell growth [GO:0030307]; protein stabilization [GO:0050821] nucleoplasm [GO:0005654]; transcription factor TFIID complex [GO:0005669]; transcription factor TFTC complex [GO:0033276] protein heterodimerization activity [GO:0046982]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; transcription corepressor activity [GO:0003714] 0.96222 -2.0331 KGPNQGRLVPR 0 0 0 9.9617 9.86482 9.98897 0 0 0 0 0 0 8.54342 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HBR0 S38AA_HUMAN Putative sodium-coupled neutral amino acid transporter 10 (Solute carrier family 38 member 10) SLC38A10 PP1744 Homo sapiens (Human) amino acid transmembrane transport [GO:0003333]; bone development [GO:0060348]; sodium ion transport [GO:0006814] Golgi apparatus [GO:0005794]; membrane [GO:0016020] L-amino acid transmembrane transporter activity [GO:0015179] 0.96031 -1.8094 EIHQQRQEDEEDKPR 0 0 0 0 0 8.87354 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4763 0 0 0 0 0 0 Q9HBT6 CAD20_HUMAN Cadherin-20 CDH20 CDH7L3 Homo sapiens (Human) adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] adherens junction [GO:0005912]; catenin complex [GO:0016342] cadherin binding [GO:0045296]; calcium ion binding [GO:0005509] 0.95131 -1.4309 EAQAGAAPKTRQDMLPEIESLSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.1634 8.89836 0 0 0 0 0 0 0 0 0 0 0 Q9HBU6 EKI1_HUMAN Ethanolamine kinase 1 (EKI 1) (EC 2.7.1.82) ETNK1 EKI1 Homo sapiens (Human) phosphatidylethanolamine biosynthetic process [GO:0006646]; phosphorylation [GO:0016310] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020] ATP binding [GO:0005524]; ethanolamine kinase activity [GO:0004305] 0.89888 -0.59809 TELLVDRDEEVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.12011 Q9HBU9 POPD2_HUMAN Popeye domain-containing protein 2 (Popeye protein 2) POPDC2 POP2 Homo sapiens (Human) heart development [GO:0007507]; regulation of heart rate [GO:0002027]; regulation of membrane potential [GO:0042391]; skeletal muscle tissue development [GO:0007519]; striated muscle cell differentiation [GO:0051146] membrane [GO:0016020]; sarcolemma [GO:0042383] cAMP binding [GO:0030552] 0.97031 -3.2409 LSRPDSGILASR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.1852 0 0 0 0 8.40259 0 0 0 Q9HBV1 POPD3_HUMAN Popeye domain-containing protein 3 (Popeye protein 3) POPDC3 POP3 Homo sapiens (Human) heart development [GO:0007507]; regulation of membrane potential [GO:0042391]; skeletal muscle tissue development [GO:0007519]; striated muscle cell differentiation [GO:0051146] membrane [GO:0016020]; sarcolemma [GO:0042383] cAMP binding [GO:0030552] 0.96947 -4.6055 ERNSSLWK 0 0 0 0 0 0 0 0 0 0 0 8.88679 0 0 0 0 0 0 0 0 0 0 0 9.32513 0 0 0 Q9HBW9 AGRL4_HUMAN "Adhesion G protein-coupled receptor L4 (EGF, latrophilin and seven transmembrane domain-containing protein 1) (EGF-TM7-latrophilin-related protein) (ETL protein)" ADGRL4 ELTD1 ETL UNQ202/PRO228 Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186]; protein-containing complex assembly [GO:0065003] cytoplasmic vesicle [GO:0031410]; membrane [GO:0016020]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; G protein-coupled receptor activity [GO:0004930] 0.95016 -1.3838 TVNNFVQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.54832 0 0 0 0 0 0 Q9HBX8 LGR6_HUMAN Leucine-rich repeat-containing G-protein coupled receptor 6 LGR6 UNQ6427/PRO21331 VTS20631 Homo sapiens (Human) axon guidance [GO:0007411]; bone regeneration [GO:1990523]; cell population proliferation [GO:0008283]; G protein-coupled receptor signaling pathway [GO:0007186]; negative chemotaxis [GO:0050919]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of Wnt signaling pathway [GO:0030177]; Wnt signaling pathway [GO:0016055] plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; vesicle [GO:0031982] heparin binding [GO:0008201]; protein-hormone receptor activity [GO:0016500]; Roundabout binding [GO:0048495]; transmembrane signaling receptor activity [GO:0004888] 0.86978 0.041319 LQEFPVAIR 0 0 14.0841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3529 0 0 Q9HBX9 RXFP1_HUMAN Relaxin receptor 1 (Leucine-rich repeat-containing G-protein coupled receptor 7) (Relaxin family peptide receptor 1) RXFP1 LGR7 Homo sapiens (Human) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; extracellular matrix organization [GO:0030198]; hormone-mediated signaling pathway [GO:0009755]; lung connective tissue development [GO:0060427]; myofibroblast differentiation [GO:0036446]; nipple morphogenesis [GO:0060658]; parturition [GO:0007567] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; hormone binding [GO:0042562]; metal ion binding [GO:0046872] 0.84868 0.15444 NYHDLQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.20955 0 0 0 0 0 0 0 0 0 0 0 Q9HBY0 NOX3_HUMAN NADPH oxidase 3 (EC 1.6.3.-) (Mitogenic oxidase 2) (MOX-2) (gp91phox homolog 3) (GP91-3) NOX3 MOX2 Homo sapiens (Human) defense response [GO:0006952]; detection of gravity [GO:0009590]; otolith development [GO:0048840]; superoxide anion generation [GO:0042554]; temperature homeostasis [GO:0001659] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; NADPH oxidase complex [GO:0043020]; plasma membrane [GO:0005886] superoxide-generating NAD(P)H oxidase activity [GO:0016175] 0.90864 -0.74364 LGNTPNESYLNPVR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.57156 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HBY8 SGK2_HUMAN Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 2) SGK2 Homo sapiens (Human) intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of transporter activity [GO:0032411]; protein phosphorylation [GO:0006468]; regulation of cell growth [GO:0001558]; regulation of cell population proliferation [GO:0042127]; response to oxidative stress [GO:0006979] cytosol [GO:0005829]; nucleoplasm [GO:0005654] ATP binding [GO:0005524]; potassium channel regulator activity [GO:0015459]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; sodium channel regulator activity [GO:0017080] 0.8997 -0.69099 ANGNINLGPSANPNAQPTDFDFLK 0 0 0 0 0 11.1224 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.39378 0 0 Q9HBZ2 ARNT2_HUMAN Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2) (Class E basic helix-loop-helix protein 1) (bHLHe1) ARNT2 BHLHE1 KIAA0307 Homo sapiens (Human) brain development [GO:0007420]; central nervous system development [GO:0007417]; in utero embryonic development [GO:0001701]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; response to hypoxia [GO:0001666] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "aryl hydrocarbon receptor binding [GO:0017162]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.95561 -1.6375 MAVSHMKSMR 0 0 0 0 11.695 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HC07 TM165_HUMAN Transmembrane protein 165 (Transmembrane protein PT27) (Transmembrane protein TPARL) TMEM165 TPARL Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; Golgi calcium ion homeostasis [GO:0032468]; Golgi calcium ion transport [GO:0032472]; intracellular calcium ion homeostasis [GO:0006874]; manganese ion transmembrane transport [GO:0071421]; protein N-linked glycosylation [GO:0006487]; regulation of lysosomal lumen pH [GO:0035751] early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; trans-Golgi network membrane [GO:0032588] calcium ion transmembrane transporter activity [GO:0015085]; manganese ion transmembrane transporter activity [GO:0005384] 0.81942 0.21879 EGLKMSPDEGQEELEEVQAELK 13.8506 14.0138 0 0 0 0 0 0 0 13.0589 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HC10 OTOF_HUMAN Otoferlin (Fer-1-like protein 2) OTOF FER1L2 Homo sapiens (Human) membrane fusion [GO:0061025]; regulation of neurotransmitter secretion [GO:0046928]; sensory perception of sound [GO:0007605]; synaptic vesicle exocytosis [GO:0016079] basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; presynaptic membrane [GO:0042734]; synaptic vesicle membrane [GO:0030672] calcium ion binding [GO:0005509] 0.85012 0.16196 SWWPDQR 0 13.2083 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HC21 TPC_HUMAN Mitochondrial thiamine pyrophosphate carrier (Mitochondrial thiamine pyrophosphate transporter) (MTPPT) (Mitochondrial uncoupling protein 1) (Solute carrier family 25 member 19) SLC25A19 DNC MUP1 Homo sapiens (Human) deoxynucleotide transport [GO:0030302]; thiamine pyrophosphate transmembrane transport [GO:0030974]; thiamine-containing compound metabolic process [GO:0042723] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; nucleus [GO:0005634] antiporter activity [GO:0015297]; deoxynucleotide transmembrane transporter activity [GO:0030233]; thiamine pyrophosphate transmembrane transporter activity [GO:0090422]; thiamine transmembrane transporter activity [GO:0015234] 0.91033 -0.7473 HLYKWAIPAEGKK 0 0 0 0 0 0 0 0 0 9.273 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HC24 LFG4_HUMAN Protein lifeguard 4 (Golgi anti-apoptotic protein) (Protein S1R) (Transmembrane BAX inhibitor motif-containing protein 4) (Z-protein) TMBIM4 GAAP LFG4 CGI-119 Homo sapiens (Human) apoptotic process [GO:0006915]; locomotory behavior [GO:0007626]; negative regulation of apoptotic process [GO:0043066]; negative regulation of neuron apoptotic process [GO:0043524]; regulation of calcium-mediated signaling [GO:0050848] Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; membrane [GO:0016020] 0.95145 -1.4402 ADPDPRYPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14.6588 0 0 0 0 0 0 0 0 0 Q9HC29 NOD2_HUMAN Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) (Inflammatory bowel disease protein 1) NOD2 CARD15 Homo sapiens (Human) biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gamma-delta T cell activation [GO:0046645]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; mitochondrion [GO:0005739]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; vesicle [GO:0031982] actin binding [GO:0003779]; ATP binding [GO:0005524]; CARD domain binding [GO:0050700]; enzyme binding [GO:0019899]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; muramyl dipeptide binding [GO:0032500]; pattern recognition receptor activity [GO:0038187]; peptidoglycan binding [GO:0042834]; protein kinase binding [GO:0019901]; protein tyrosine kinase activator activity [GO:0030296]; protein-containing complex binding [GO:0044877]; signaling receptor activator activity [GO:0030546] 0.96761 -2.7492 LGCRDTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.89609 0 0 0 0 0 9.12169 0 0 Q9HC38 GLOD4_HUMAN Glyoxalase domain-containing protein 4 GLOD4 C17orf25 CGI-150 My027 Homo sapiens (Human) extracellular exosome [GO:0070062]; mitochondrion [GO:0005739] cadherin binding [GO:0045296] 0.97001 -4.3434 ELPDLEDLMKR 0 0 0 9.59421 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1018 0 8.52775 0 0 0 0 0 9.35993 Q9HC52 CBX8_HUMAN Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (hPc3) (Rectachrome 1) CBX8 PC3 RC1 Homo sapiens (Human) chromatin organization [GO:0006325]; negative regulation of transcription by RNA polymerase II [GO:0000122] chromatin [GO:0000785]; heterochromatin [GO:0000792]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PcG protein complex [GO:0031519]; PRC1 complex [GO:0035102] chromatin binding [GO:0003682]; methylated histone binding [GO:0035064]; single-stranded RNA binding [GO:0003727]; ubiquitin-protein transferase activator activity [GO:0097027] 0.36209 0.74748 IPYPGRSPQDLASTSRAR 0 0 0 0 0 0 0 0 0 9.06099 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5669 0 Q9HC56 PCDH9_HUMAN Protocadherin-9 PCDH9 Homo sapiens (Human) cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] cell-cell contact zone [GO:0044291]; growth cone [GO:0030426]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.96133 -2.6007 EETAIHK 0 0 0 0 0 0 0 0 0 10.7718 0 0 11.346 0 0 11.7358 0 0 0 0 0 0 0 0 0 0 0 Q9HC58 NCKX3_HUMAN Sodium/potassium/calcium exchanger 3 (Na(+)/K(+)/Ca(2+)-exchange protein 3) (Solute carrier family 24 member 3) SLC24A3 NCKX3 Homo sapiens (Human) bone mineralization [GO:0030282]; calcium ion transmembrane transport [GO:0070588]; intracellular calcium ion homeostasis [GO:0006874]; monoatomic ion transport [GO:0006811]; negative regulation of gene expression [GO:0010629]; positive regulation of gene expression [GO:0010628]; potassium ion transmembrane transport [GO:0071805]; sodium ion transmembrane transport [GO:0035725]; transport across blood-brain barrier [GO:0150104] cell periphery [GO:0071944]; plasma membrane [GO:0005886] "calcium channel activity [GO:0005262]; calcium, potassium:sodium antiporter activity [GO:0008273]; symporter activity [GO:0015293]" 0.94683 -1.3509 KANFHRK 0 12.2295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HC62 SENP2_HUMAN Sentrin-specific protease 2 (EC 3.4.22.-) (Axam2) (SMT3-specific isopeptidase 2) (Smt3ip2) (Sentrin/SUMO-specific protease SENP2) SENP2 KIAA1331 Homo sapiens (Human) fat cell differentiation [GO:0045444]; heart development [GO:0007507]; labyrinthine layer development [GO:0060711]; mRNA transport [GO:0051028]; negative regulation of chromatin binding [GO:0035562]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein destabilization [GO:0031648]; protein desumoylation [GO:0016926]; protein sumoylation [GO:0016925]; protein transport [GO:0015031]; regulation of DNA endoreduplication [GO:0032875]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of Wnt signaling pathway [GO:0030111]; spongiotrophoblast layer development [GO:0060712]; trophoblast giant cell differentiation [GO:0060707]; Wnt signaling pathway [GO:0016055] cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605] deSUMOylase activity [GO:0016929]; SUMO-specific endopeptidase activity [GO:0070139] 0.9626 -2.5352 LDCFIHQVK 0 0 0 0 9.4204 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HC77 CENPJ_HUMAN Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1) CENPJ CPAP LAP LIP1 Homo sapiens (Human) astral microtubule nucleation [GO:0030954]; cell division [GO:0051301]; centriole elongation [GO:0061511]; centriole replication [GO:0007099]; cilium assembly [GO:0060271]; microtubule nucleation [GO:0007020]; microtubule polymerization [GO:0046785]; motile cilium assembly [GO:0044458]; non-motile cilium assembly [GO:1905515]; positive regulation of centriole elongation [GO:1903724]; positive regulation of centriole replication [GO:0046601]; positive regulation of establishment of protein localization [GO:1904951]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of non-motile cilium assembly [GO:1902857]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of spindle assembly [GO:1905832]; regulation of centriole replication [GO:0046599]; regulation of mitotic spindle organization [GO:0060236]; smoothened signaling pathway [GO:0007224] centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; gamma-tubulin small complex [GO:0008275]; microtubule [GO:0005874]; procentriole replication complex [GO:0120099] gamma-tubulin binding [GO:0043015]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; transcription coactivator activity [GO:0003713]; tubulin binding [GO:0015631] 0.047109 1.4501 EITFPDQTVK 0 0 0 0 0 0 0 0 0 9.5183 0 9.53961 0 0 0 10.4634 0 0 10.9818 0 0 11.1922 0 0 0 0 0 Q9HC84 MUC5B_HUMAN "Mucin-5B (MUC-5B) (Cervical mucin) (High molecular weight salivary mucin MG1) (Mucin-5 subtype B, tracheobronchial) (Sublingual gland mucin)" MUC5B MUC5 Homo sapiens (Human) extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886] metal ion binding [GO:0046872] 0.96949 -3.5187 CQWTEWFDEDYPK 0 0 0 0 0 0 0 8.99955 0 0 0 0 0 0 0 0 0 0 9.40444 0 0 0 0 0 0 0 0 Q9HC96 CAN10_HUMAN Calpain-10 (EC 3.4.22.-) (Calcium-activated neutral proteinase 10) (CANP 10) CAPN10 KIAA1845 Homo sapiens (Human) cellular component disassembly involved in execution phase of apoptosis [GO:0006921]; cellular response to insulin stimulus [GO:0032869]; positive regulation of glucose import [GO:0046326]; positive regulation of insulin secretion [GO:0032024]; positive regulation of intracellular transport [GO:0032388]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; proteolysis [GO:0006508]; regulation of actin cytoskeleton organization [GO:0032956]; type B pancreatic cell apoptotic process [GO:0097050] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886] calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; cytoskeletal protein binding [GO:0008092]; SNARE binding [GO:0000149] 0.90508 -0.72617 LPCLAGRLCFSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1218 0 0 0 0 0 0 0 0 Q9HC97 GPR35_HUMAN G-protein coupled receptor 35 (Kynurenic acid receptor) (KYNA receptor) GPR35 Homo sapiens (Human) chemokine-mediated signaling pathway [GO:0070098]; cytoskeleton organization [GO:0007010]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of neuronal action potential [GO:1904456]; negative regulation of voltage-gated calcium channel activity [GO:1901386]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of Rho protein signal transduction [GO:0035025] plasma membrane [GO:0005886] C-X-C chemokine receptor activity [GO:0016494]; G protein-coupled receptor activity [GO:0004930] 0.59852 0.44286 SQDSLCVTLA 0 9.25271 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HCC0 MCCB_HUMAN "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta)" MCCC2 MCCB Homo sapiens (Human) branched-chain amino acid catabolic process [GO:0009083]; coenzyme A metabolic process [GO:0015936]; leucine catabolic process [GO:0006552] "3-methylcrotonyl-CoA carboxylase complex, mitochondrial [GO:0002169]; cytosol [GO:0005829]; methylcrotonoyl-CoA carboxylase complex [GO:1905202]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]" ATP binding [GO:0005524]; methylcrotonoyl-CoA carboxylase activity [GO:0004485] 0.95526 -1.5652 ALHISRGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.35837 0 0 0 0 0 Q9HCC9 LST2_HUMAN Lateral signaling target protein 2 homolog (hLst2) (Zinc finger FYVE domain-containing protein 28) ZFYVE28 KIAA1643 LST2 Homo sapiens (Human) negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175] cytosol [GO:0005829]; early endosome membrane [GO:0031901] metal ion binding [GO:0046872]; phosphatidylinositol-3-phosphate binding [GO:0032266] 0.95209 -1.4511 DFCVKFPEEIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.9026 0 0 9.75221 0 0 0 0 Q9HCD5 NCOA5_HUMAN Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA) NCOA5 KIAA1637 Homo sapiens (Human) glucose homeostasis [GO:0042593]; insulin receptor signaling pathway [GO:0008286]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of signal transduction [GO:0009966] actin cytoskeleton [GO:0015629]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654] chromatin binding [GO:0003682]; RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714] 0.88439 -0.19101 DPYGFGDSR 10.1906 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1268 0 0 0 0 Q9HCD6 TANC2_HUMAN "Protein TANC2 (Tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 2)" TANC2 KIAA1148 KIAA1636 Homo sapiens (Human) dense core granule cytoskeletal transport [GO:0099519]; regulation of dendritic spine development [GO:0060998]; regulation of dendritic spine morphogenesis [GO:0061001] axon [GO:0030424]; dendritic spine [GO:0043197] 0.87662 -0.0084648 YSQTPQIGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7577 0 0 0 0 0 0 0 0 Q9HCE0 EPG5_HUMAN Ectopic P granules protein 5 homolog EPG5 KIAA1632 Homo sapiens (Human) autophagosome maturation [GO:0097352]; cellular response to dsDNA [GO:1990786]; endocytic recycling [GO:0032456]; endosome to lysosome transport [GO:0008333]; nucleotide transport [GO:0006862]; toll-like receptor 9 signaling pathway [GO:0034162] cytoplasm [GO:0005737]; lysosome [GO:0005764]; perinuclear region of cytoplasm [GO:0048471] 0.8961 -0.54209 KVLETILK 0 9.27237 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3386 Q9HCE1 MOV10_HUMAN Helicase MOV-10 (EC 3.6.4.13) (Armitage homolog) (Moloney leukemia virus 10 protein) MOV10 KIAA1631 Homo sapiens (Human) 3'-UTR-mediated mRNA destabilization [GO:0061158]; defense response to virus [GO:0051607]; miRNA-mediated gene silencing [GO:0035195]; miRNA-mediated gene silencing by mRNA destabilization [GO:0035279]; ncRNA-mediated post-transcriptional gene silencing [GO:0035194]; positive regulation of mRNA catabolic process [GO:0061014]; regulation of neuron projection arborization [GO:0150011]; retrotransposon silencing [GO:0010526]; retrotransposon silencing by mRNA destabilization [GO:0141008] cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; P granule [GO:0043186]; P-body [GO:0000932] 5'-3' RNA helicase activity [GO:0032574]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; RNA binding [GO:0003723] 0.96415 -2.4192 AEYLHGK 0 0 0 0 0 0 0 0 0 10.7974 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4814 0 0 0 Q9HCE3 ZN532_HUMAN Zinc finger protein 532 ZNF532 KIAA1629 Homo sapiens (Human) nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.95916 -1.7332 IEVTCNHCTK 10.6192 11.7442 10.3373 0 11.8716 11.9949 9.81946 0 0 12.546 0 12.4012 11.0402 0 0 0 0 0 0 0 0 10.269 0 9.99788 9.88609 0 0 Q9HCE5 MET14_HUMAN N6-adenosine-methyltransferase non-catalytic subunit (Methyltransferase-like protein 14) (hMETTL14) METTL14 KIAA1627 Homo sapiens (Human) "forebrain radial glial cell differentiation [GO:0021861]; gliogenesis [GO:0042063]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; mRNA methylation [GO:0080009]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of hematopoietic progenitor cell differentiation [GO:1901533]; positive regulation of translation [GO:0045727]; regulation of neuron differentiation [GO:0045664]; spermatogenesis [GO:0007283]; stem cell population maintenance [GO:0019827]" nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA N6-methyladenosine methyltransferase complex [GO:0036396] mRNA (N6-adenosine)-methyltransferase activity [GO:0001734]; mRNA binding [GO:0003729] 0.96746 -2.8565 DEQREIAETR 0 0 0 0 0 0 0 0 0 0 0 9.40448 0 0 0 0 0 0 0 0 0 0 0 0 11.1676 0 0 Q9HCE6 ARGAL_HUMAN Rho guanine nucleotide exchange factor 10-like protein (GrinchGEF) ARHGEF10L GRINCHGEF KIAA1626 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; positive regulation of stress fiber assembly [GO:0051496]; regulation of small GTPase mediated signal transduction [GO:0051056]; SREBP signaling pathway [GO:0032933] cytosol [GO:0005829] GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085] 0.89735 -0.53794 ILQDYRNPLMEMEPK 0 0 10.6045 0 0 0 0 10.8629 0 0 0 0 0 0 0 0 0 0 0 8.67299 0 0 0 0 0 0 0 Q9HCE7 SMUF1_HUMAN E3 ubiquitin-protein ligase SMURF1 (hSMURF1) (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase SMURF1) (SMAD ubiquitination regulatory factor 1) (SMAD-specific E3 ubiquitin-protein ligase 1) SMURF1 KIAA1625 Homo sapiens (Human) "BMP signaling pathway [GO:0030509]; cell differentiation [GO:0030154]; ectoderm development [GO:0007398]; engulfment of target by autophagosome [GO:0061736]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of axon extension [GO:0045773]; positive regulation of dendrite extension [GO:1903861]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein export from nucleus [GO:0006611]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein polyubiquitination [GO:0000209]; protein targeting to vacuole involved in autophagy [GO:0071211]; protein ubiquitination [GO:0016567]; receptor catabolic process [GO:0032801]; substrate localization to autophagosome [GO:0061753]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent SMAD protein catabolic process [GO:0030579]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] activin binding [GO:0048185]; I-SMAD binding [GO:0070411]; phospholipid binding [GO:0005543]; R-SMAD binding [GO:0070412]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.93014 -1.2483 IYFVDHNNR 0 0 0 0 0 9.29013 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HCE9 ANO8_HUMAN Anoctamin-8 (Transmembrane protein 16H) ANO8 KIAA1623 TMEM16H Homo sapiens (Human) chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; monoatomic ion transmembrane transport [GO:0034220] endoplasmic reticulum lumen [GO:0005788]; plasma membrane [GO:0005886] chloride channel activity [GO:0005254]; intracellular calcium activated chloride channel activity [GO:0005229] 0.0082645 2.193 VESIGQWQK 0 0 0 0 0 0 0 0 9.37286 0 0 9.82998 0 0 0 0 0 0 0 0 0 0 0 0 11.3136 0 9.6722 Q9HCF6 TRPM3_HUMAN Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC-3) (LTrpC3) (Melastatin-2) (MLSN2) TRPM3 KIAA1616 LTRPC3 Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; monoatomic cation transmembrane transport [GO:0098655]; monoatomic cation transport [GO:0006812]; protein tetramerization [GO:0051262] plasma membrane [GO:0005886] calcium channel activity [GO:0005262]; monoatomic cation channel activity [GO:0005261] 0.9278 -1.2244 ATSSHSVAKEPK 9.12466 9.12112 11.0025 0 0 0 0 8.63089 0 9.41631 0 9.24479 0 0 0 0 0 0 0 0 9.42517 0 10.7601 0 10.0154 0 0 Q9HCG1 ZN160_HUMAN Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18) ZNF160 KIAA1611 Homo sapiens (Human) hemopoiesis [GO:0030097]; regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.70456 0.3703 CTIKDLLPKEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.67509 0 0 0 0 0 0 0 0 0 0 Q9HCG7 GBA2_HUMAN Non-lysosomal glucosylceramidase (NLGase) (EC 3.2.1.45) (Beta-glucocerebrosidase 2) (Beta-glucosidase 2) (Bile acid beta-glucosidase GBA2) (Bile acid glucosyl transferase GBA2) (Cholesterol glucosyltransferase GBA2) (EC 2.4.1.-) (Cholesteryl-beta-glucosidase GBA2) (EC 3.2.1.-) (Glucosylceramidase 2) (Non-lysosomal cholesterol glycosyltransferase) (Non-lysosomal galactosylceramidase) (EC 3.2.1.46) (Non-lysosomal glycosylceramidase) GBA2 KIAA1605 SPG46 AD035 Homo sapiens (Human) bile acid metabolic process [GO:0008206]; carbohydrate metabolic process [GO:0005975]; central nervous system development [GO:0007417]; central nervous system neuron development [GO:0021954]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycoside catabolic process [GO:0016139]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; regulation of actin filament polymerization [GO:0030833]; regulation of membrane lipid distribution [GO:0097035]; regulation of microtubule polymerization [GO:0031113] cytosol [GO:0005829]; extrinsic component of endoplasmic reticulum membrane [GO:0042406]; extrinsic component of Golgi membrane [GO:0090498]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; plasma membrane [GO:0005886]; smooth endoplasmic reticulum [GO:0005790] beta-glucosidase activity [GO:0008422]; galactosylceramidase activity [GO:0004336]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; steryl-beta-glucosidase activity [GO:0050295] 0.89849 -0.59231 GQVHYRR 0 0 8.63554 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4762 0 0 Q9HCG8 CWC22_HUMAN Pre-mRNA-splicing factor CWC22 homolog (Nucampholin homolog) (fSAPb) CWC22 KIAA1604 NCM Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA splicing, via spliceosome [GO:0048024]" catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2-type catalytic step 1 spliceosome [GO:0071006]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005] RNA binding [GO:0003723] 0.96959 -4.0576 NSSPEDR 0 9.79357 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.31213 0 0 Q9HCH0 NCK5L_HUMAN Nck-associated protein 5-like (NCKAP5-like) (Centrosomal protein of 169 kDa) (Cep169) NCKAP5L CEP169 KIAA1602 FP1193 Homo sapiens (Human) microtubule bundle formation [GO:0001578]; microtubule depolymerization [GO:0007019] centrosome [GO:0005813]; cytoplasm [GO:0005737]; microtubule plus-end [GO:0035371] 0.1776 0.96405 AGSESPHPGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15.935 0 15.852 0 0 0 0 0 0 0 0 0 15.3123 Q9HCI5 MAGE1_HUMAN Melanoma-associated antigen E1 (Alpha-dystrobrevin-associated MAGE Protein) (DAMAGE) (Hepatocellular carcinoma-associated protein 1) (MAGE-E1 antigen) MAGEE1 HCA1 KIAA1587 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] dendrite [GO:0030425]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211] 0.89003 -0.47029 ALRYVARIHR 10.638 10.6383 10.6492 0 0 0 0 8.66519 0 12.6091 12.9108 12.6568 8.55562 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HCI6 K1586_HUMAN E3 SUMO-protein ligase KIAA1586 (EC 2.3.2.-) (E3 SUMO-protein transferase KIAA1586) KIAA1586 Homo sapiens (Human) protein sumoylation [GO:0016925] SUMO ligase activity [GO:0061665] 0.941 -1.3113 STNIKKAQK 9.81804 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HCJ5 ZSWM6_HUMAN Zinc finger SWIM domain-containing protein 6 ZSWIM6 KIAA1577 Homo sapiens (Human) striatal medium spiny neuron differentiation [GO:0021773] Cul2-RING ubiquitin ligase complex [GO:0031462] zinc ion binding [GO:0008270] 0.92693 -1.1946 FERIPEPVQRR 0 0 0 10.6302 0 0 0 0 0 0 0 0 0 0 9.6618 0 9.59498 0 0 0 0 0 0 0 0 0 0 Q9HCJ6 VAT1L_HUMAN Synaptic vesicle membrane protein VAT-1 homolog-like (EC 1.-.-.-) VAT1L KIAA1576 Homo sapiens (Human) oxidoreductase activity [GO:0016491]; zinc ion binding [GO:0008270] 0.91718 -0.85674 AMPEPQDGELKIR 0 0 0 0 0 0 0 0 0 0 10.2054 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7143 0 Q9HCK0 ZBT26_HUMAN Zinc finger and BTB domain-containing protein 26 (Zinc finger protein 481) (Zinc finger protein Bioref) ZBTB26 KIAA1572 ZNF481 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of cytokine production [GO:0001817]; regulation of immune system process [GO:0002682] nucleus [GO:0005634] identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific double-stranded DNA binding [GO:1990837] 0.92474 -0.98496 FENYGDSMLQK 0 10.8752 0 0 0 0 10.2772 0 10.2413 9.21476 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HCK1 ZDBF2_HUMAN DBF4-type zinc finger-containing protein 2 ZDBF2 KIAA1571 Homo sapiens (Human) DNA methylation involved in embryo development [GO:0043045]; genomic imprinting [GO:0071514] nucleus [GO:0005634] nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270] 0.97 -4.1358 EKHAEFQGR 0 0 0 0 0 0 10.4201 9.45666 0 0 9.25231 10.1712 0 10.4508 0 0 0 8.74302 9.1682 0 0 0 0 9.84536 0 0 0 Q9HCK4 ROBO2_HUMAN Roundabout homolog 2 ROBO2 KIAA1568 Homo sapiens (Human) aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in luteolysis [GO:0061364]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; brain development [GO:0007420]; cell-cell adhesion [GO:0098609]; cellular response to hormone stimulus [GO:0032870]; central nervous system development [GO:0007417]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; metanephros development [GO:0001656]; negative regulation of negative chemotaxis [GO:0050925]; negative regulation of synapse assembly [GO:0051964]; olfactory bulb interneuron development [GO:0021891]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; pulmonary valve morphogenesis [GO:0003184]; retinal ganglion cell axon guidance [GO:0031290]; ureteric bud development [GO:0001657]; ventricular septum morphogenesis [GO:0060412] axolemma [GO:0030673]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802] 0.92707 -1.1914 QPQFIQGYRVMYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.52025 0 0 0 0 0 0 0 0 0 0 Q9HCK8 CHD8_HUMAN Chromodomain-helicase-DNA-binding protein 8 (CHD-8) (EC 3.6.4.12) (ATP-dependent helicase CHD8) (Helicase with SNF2 domain 1) CHD8 HELSNF1 KIAA1564 Homo sapiens (Human) brain development [GO:0007420]; chromatin remodeling [GO:0006338]; digestive tract development [GO:0048565]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of fibroblast apoptotic process [GO:2000270]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; prepulse inhibition [GO:0060134]; social behavior [GO:0035176]; Wnt signaling pathway [GO:0016055] chromatin [GO:0000785]; MLL1 complex [GO:0071339]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] armadillo repeat domain binding [GO:0070016]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent chromatin remodeler activity [GO:0140658]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; p53 binding [GO:0002039] 0.96218 -2.4512 EDEESSIQK 0 0 0 0 0 0 0 0 0 0 0 0 9.06706 0 0 0 9.87662 9.1954 0 9.9334 0 0 0 0 0 0 0 Q9HCL0 PCD18_HUMAN Protocadherin-18 PCDH18 KIAA1562 Homo sapiens (Human) brain development [GO:0007420]; cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.93862 -1.2969 FSLKDSGR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.89382 0 10.1301 0 0 0 0 0 0 0 0 0 0 0 Q9HCL2 GPAT1_HUMAN "Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAT-1) (EC 2.3.1.15)" GPAM GPAT1 KIAA1560 Homo sapiens (Human) activated T cell proliferation [GO:0050798]; activation-induced cell death of T cells [GO:0006924]; acyl-CoA metabolic process [GO:0006637]; CDP-diacylglycerol biosynthetic process [GO:0016024]; defense response to virus [GO:0051607]; diacylglycerol biosynthetic process [GO:0006651]; fatty acid homeostasis [GO:0055089]; fatty acid metabolic process [GO:0006631]; glycerol-3-phosphate metabolic process [GO:0006072]; negative regulation of activation-induced cell death of T cells [GO:0070236]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylglycerol biosynthetic process [GO:0006655]; phospholipid homeostasis [GO:0055091]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of multicellular organism growth [GO:0040018]; regulation of cytokine production [GO:0001817]; response to glucose [GO:0009749]; triglyceride biosynthetic process [GO:0019432] mitochondrial membrane [GO:0031966]; mitochondrial outer membrane [GO:0005741]; plasma membrane [GO:0005886] glycerol-3-phosphate O-acyltransferase activity [GO:0004366]; sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity [GO:0102420] 0.89741 -0.58354 NESLWSVAR 0 0 0 0 0 0 0 0 9.19362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.515 0 0 Q9HCL3 ZFP14_HUMAN Zinc finger protein 14 homolog (Zfp-14) (Zinc finger protein 531) ZFP14 KIAA1559 ZNF531 Homo sapiens (Human) blastocyst hatching [GO:0001835]; regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96902 -4.5499 AFRQHSHLTQHQK 10.1387 10.0373 10.5619 0 0 0 0 0 0 10.7917 9.5292 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4996 0 Q9HCM1 RESF1_HUMAN Retroelement silencing factor 1 RESF1 C12orf35 KIAA1551 Homo sapiens (Human) negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309] nucleus [GO:0005634] histone binding [GO:0042393]; histone methyltransferase binding [GO:1990226] 0.89778 -0.55063 ESLNGLTSHGK 0 0 0 11.6954 12.2156 0 0 0 10.7963 0 0 0 9.46984 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HCM2 PLXA4_HUMAN Plexin-A4 PLXNA4 KIAA1550 PLXNA4A PLXNA4B UNQ2820/PRO34003 Homo sapiens (Human) anterior commissure morphogenesis [GO:0021960]; chemorepulsion of branchiomotor axon [GO:0021793]; embryonic heart tube development [GO:0035050]; facial nerve structural organization [GO:0021612]; glossopharyngeal nerve morphogenesis [GO:0021615]; maintenance of synapse structure [GO:0099558]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; postganglionic parasympathetic fiber development [GO:0021784]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of negative chemotaxis [GO:0050923]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; sympathetic nervous system development [GO:0048485]; sympathetic neuron axon guidance [GO:0097492]; trigeminal nerve structural organization [GO:0021637]; vagus nerve morphogenesis [GO:0021644] cerebellar climbing fiber to Purkinje cell synapse [GO:0150053]; plasma membrane [GO:0005886]; semaphorin receptor complex [GO:0002116] semaphorin receptor activity [GO:0017154] 0.96958 -5.5127 DIPSYKNWVERYYSDIGK 9.32136 9.30686 9.31039 0 0 9.2023 0 0 0 0 0 0 0 0 0 11.4067 0 0 0 0 10.979 9.44777 0 0 0 0 0 Q9HCM4 E41L5_HUMAN Band 4.1-like protein 5 (Erythrocyte membrane protein band 4.1-like 5) EPB41L5 KIAA1548 Homo sapiens (Human) "actomyosin structure organization [GO:0031032]; apical constriction [GO:0003383]; axial mesoderm morphogenesis [GO:0048319]; cellular response to transforming growth factor beta stimulus [GO:0071560]; ectoderm development [GO:0007398]; embryonic foregut morphogenesis [GO:0048617]; endoderm development [GO:0007492]; epithelial to mesenchymal transition [GO:0001837]; in utero embryonic development [GO:0001701]; left/right axis specification [GO:0070986]; mesoderm migration involved in gastrulation [GO:0007509]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of protein binding [GO:0032091]; neural plate morphogenesis [GO:0001839]; paraxial mesoderm development [GO:0048339]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein binding [GO:0032092]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of establishment of protein localization [GO:0070201]; somite rostral/caudal axis specification [GO:0032525]; substrate-dependent cell migration, cell attachment to substrate [GO:0006931]; unidimensional cell growth [GO:0009826]" adherens junction [GO:0005912]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleoplasm [GO:0005654]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587] cytoskeletal protein binding [GO:0008092]; protein domain specific binding [GO:0019904] 0.95097 -1.416 FYSSEPNNLR 0 0 0 0 0 0 0 0 10.2363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HCM7 FBSL_HUMAN Fibrosin-1-like protein (AUTS2-like protein) (HBV X-transactivated gene 9 protein) (HBV XAg-transactivated protein 9) FBRSL1 AUTS2L KIAA1545 XTP9 Homo sapiens (Human) RNA binding [GO:0003723] 0.88383 -0.17137 AAPGDVK 8.6462 0 9.32477 0 0 0 0 0 0 12.0907 0 0 0 0 0 11.1354 9.58075 10.0959 0 8.60366 0 0 0 0 0 0 0 Q9HCM9 TRI39_HUMAN E3 ubiquitin-protein ligase TRIM39 (EC 2.3.2.27) (RING finger protein 23) (RING-type E3 ubiquitin transferase TRIM39) (Testis-abundant finger protein) (Tripartite motif-containing protein 39) TRIM39 RNF23 TFP Homo sapiens (Human) apoptotic process [GO:0006915]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of cell cycle G1/S phase transition [GO:1902806] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634] identical protein binding [GO:0042802]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.95587 -1.549 SVKFVETR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8973 0 0 0 0 0 0 0 0 0 0 Q9HCN3 PGAP6_HUMAN Post-GPI attachment to proteins factor 6 (EC 3.1.1.4) (GPI processing phospholipase A2) (GPI-PLA2) (Protein M83) (Transmembrane protein 6) (Transmembrane protein 8) (Transmembrane protein 8A) PGAP6 TMEM6 TMEM8 TMEM8A Homo sapiens (Human) lipid metabolic process [GO:0006629] extracellular exosome [GO:0070062]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886] phospholipase A2 activity [GO:0004623] 0.86335 0.076053 VLTCTGAPWPCR 0 0 0 0 0 0 0 0 0 9.63403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HCP6 HHATL_HUMAN Protein-cysteine N-palmitoyltransferase HHAT-like protein (Glycerol uptake/transporter homolog) (Hedgehog acyltransferase-like protein) HHATL C3orf3 GUP1 KIAA1173 Homo sapiens (Human) negative regulation of N-terminal protein palmitoylation [GO:0060262] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; perinuclear region of cytoplasm [GO:0048471] acyltransferase activity [GO:0016746] 0.8134 0.22282 LAEWGPLAR 0 0 0 8.44332 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HCQ5 GALT9_HUMAN Polypeptide N-acetylgalactosaminyltransferase 9 (EC 2.4.1.41) (Polypeptide GalNAc transferase 9) (GalNAc-T9) (pp-GaNTase 9) (Protein-UDP acetylgalactosaminyltransferase 9) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 9) GALNT9 Homo sapiens (Human) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139] carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; polypeptide N-acetylgalactosaminyltransferase activity [GO:0004653] 0.9217 -0.93708 NWIKHARH 0 0 0 0 0 0 0 0 8.21485 9.33085 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.60268 0 Q9HCQ7 NPVF_HUMAN Pro-FMRFamide-related neuropeptide VF [Cleaved into: Neuropeptide NPSF; Neuropeptide RFRP-1; Neuropeptide RFRP-2; Neuropeptide NPVF (Neuropeptide RFRP-3)] NPVF C7orf9 RFRP Homo sapiens (Human) negative regulation of gonadotropin secretion [GO:0032277]; neuropeptide signaling pathway [GO:0007218] extracellular region [GO:0005576] signaling receptor binding [GO:0005102] 0.84166 0.17844 ENYDKYSEPRGYPK 0 11.4862 0 0 0 0 0 0 0 0 0 0 0 9.11069 0 10.6908 0 0 0 0 0 0 0 0 0 0 0 Q9HCR9 PDE11_HUMAN "Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (EC 3.1.4.35) (EC 3.1.4.53) (cAMP and cGMP phosphodiesterase 11A)" PDE11A Homo sapiens (Human) metabolic process [GO:0008152]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; signal transduction [GO:0007165] cytosol [GO:0005829]; perikaryon [GO:0043204] "3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; cyclic-nucleotide phosphodiesterase activity [GO:0004112]; metal ion binding [GO:0046872]" 0.89005 -0.45903 NRKDELPR 0 0 10.5462 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HCS2 CP4FC_HUMAN Cytochrome P450 4F12 (EC 1.14.14.1) (CYPIVF12) CYP4F12 UNQ568/PRO1129 Homo sapiens (Human) arachidonic acid metabolic process [GO:0019369]; epoxygenase P450 pathway [GO:0019373]; fatty acid metabolic process [GO:0006631]; leukotriene B4 catabolic process [GO:0036101]; long-chain fatty acid metabolic process [GO:0001676]; menaquinone catabolic process [GO:0042361]; phylloquinone catabolic process [GO:0042376]; pressure natriuresis [GO:0003095]; renal water homeostasis [GO:0003091]; sodium ion homeostasis [GO:0055078]; very long-chain fatty acid metabolic process [GO:0000038]; vitamin E metabolic process [GO:0042360]; xenobiotic metabolic process [GO:0006805] apical plasma membrane [GO:0016324]; cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231] alkane 1-monooxygenase activity [GO:0018685]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; leukotriene-B4 20-monooxygenase activity [GO:0050051]; monooxygenase activity [GO:0004497] 0.56589 0.49694 FLPDHTEPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.68951 9.94654 0 0 0 0 0 0 0 0 0 0 Q9HCS4 TF7L1_HUMAN Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF-3) TCF7L1 TCF3 Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; chromatin organization [GO:0006325]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of Wnt signaling pathway [GO:0030111] beta-catenin-TCF complex [GO:1990907]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.88413 -0.15703 WHNLSREEQAKYYELAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.77658 0 0 0 0 0 0 0 0 0 0 0 0 Q9HCS5 E41LA_HUMAN Band 4.1-like protein 4A (Erythrocyte membrane protein band 4.1-like 4A) (Protein NBL4) EPB41L4A EPB41L4 Homo sapiens (Human) actomyosin structure organization [GO:0031032] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856] cytoskeletal protein binding [GO:0008092] 0.96472 -2.7016 FYAEDPCK 0 0 9.10313 0 9.58778 0 9.41339 0 0 9.90937 0 0 0 0 11.4517 0 0 0 0 0 0 0 0 0 0 0 0 Q9HCS7 SYF1_HUMAN Pre-mRNA-splicing factor SYF1 (Protein HCNP) (XPA-binding protein 2) XAB2 HCNP KIAA1177 SYF1 PP3898 Homo sapiens (Human) "blastocyst development [GO:0001824]; cerebral cortex development [GO:0021987]; DNA-templated transcription [GO:0006351]; generation of catalytic spliceosome for first transesterification step [GO:0000349]; mRNA splicing, via spliceosome [GO:0000398]; transcription-coupled nucleotide-excision repair [GO:0006283]" catalytic step 2 spliceosome [GO:0071013]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; post-mRNA release spliceosomal complex [GO:0071014]; Prp19 complex [GO:0000974]; U2-type catalytic step 2 spliceosome [GO:0071007] 0.96807 -2.9116 ATALPARR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.097 9.62587 9.10405 0 0 0 0 0 0 Q9HCU0 CD248_HUMAN Endosialin (Tumor endothelial marker 1) (CD antigen CD248) CD248 CD164L1 TEM1 Homo sapiens (Human) anatomical structure regression [GO:0060033]; cell migration [GO:0016477]; endothelial cell apoptotic process [GO:0072577]; fibroblast migration [GO:0010761]; fibroblast proliferation [GO:0048144]; lymph node development [GO:0048535]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of fibroblast proliferation [GO:0048146] cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012] calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; extracellular matrix binding [GO:0050840]; extracellular matrix protein binding [GO:1990430] 0.67192 0.39371 EDGPSPK 0 0 0 0 0 0 0 9.89107 7.84818 0 0 9.03895 0 0 8.66966 0 8.27053 0 0 0 0 0 0 0 0 0 0 Q9HCU4 CELR2_HUMAN Cadherin EGF LAG seven-pass G-type receptor 2 (Cadherin family member 10) (Epidermal growth factor-like protein 2) (EGF-like protein 2) (Flamingo homolog 3) (Multiple epidermal growth factor-like domains protein 3) (Multiple EGF-like domains protein 3) CELSR2 CDHF10 EGFL2 KIAA0279 MEGF3 Homo sapiens (Human) "cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; G protein-coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" cytoplasm [GO:0005737]; membrane [GO:0016020]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; G protein-coupled receptor activity [GO:0004930] 0.96822 -3.6255 EDVTPGAPVLRVTASDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.04797 0 0 0 0 0 0 0 11.1418 0 Q9HCU5 PREB_HUMAN Prolactin regulatory element-binding protein (Mammalian guanine nucleotide exchange factor mSec12) PREB SEC12 Homo sapiens (Human) COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein exit from endoplasmic reticulum [GO:0032527]; protein secretion [GO:0009306]; regulation of COPII vesicle coating [GO:0003400] endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; nucleus [GO:0005634] DNA binding [GO:0003677]; GTPase activator activity [GO:0005096]; GTPase binding [GO:0051020]; guanyl-nucleotide exchange factor activity [GO:0005085] 0.77034 0.26935 CGAETQHEGLELR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3763 0 0 0 0 0 0 0 0 9.55042 0 Q9HCX3 ZN304_HUMAN Zinc finger protein 304 (KRAB-containing zinc finger protein) ZNF304 Homo sapiens (Human) angiogenesis [GO:0001525]; chromatin organization [GO:0006325]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of anoikis [GO:2000811]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of transcription by RNA polymerase II [GO:0045944] nucleus [GO:0005634] metal ion binding [GO:0046872]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.88559 -0.29523 AYSRSSHLVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5976 0 0 0 0 0 0 9.81949 0 0 0 Q9HCX4 TRPC7_HUMAN Short transient receptor potential channel 7 (TrpC7) (Transient receptor protein 7) (TRP-7) (hTRP7) TRPC7 TRP7 Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; regulation of cytosolic calcium ion concentration [GO:0051480]; single fertilization [GO:0007338] cation channel complex [GO:0034703]; cis-Golgi network [GO:0005801]; nuclear envelope [GO:0005635]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] "calcium channel activity [GO:0005262]; inositol 1,4,5 trisphosphate binding [GO:0070679]; store-operated calcium channel activity [GO:0015279]" 0.866 0.073964 SQATGELADLIQQLSEK 0 0 10.9267 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HCY8 S10AE_HUMAN Protein S100-A14 (S100 calcium-binding protein A14) (S114) S100A14 S100A15 Homo sapiens (Human) apoptotic process [GO:0006915]; calcium ion homeostasis [GO:0055074]; defense response to bacterium [GO:0042742]; positive regulation of granulocyte chemotaxis [GO:0071624]; positive regulation of monocyte chemotaxis [GO:0090026]; response to lipopolysaccharide [GO:0032496]; toll-like receptor 4 signaling pathway [GO:0034142] extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471] calcium ion binding [GO:0005509]; chemokine receptor binding [GO:0042379] 0.85767 0.1015 LEFRSFWELIGEAAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4972 0 0 0 0 0 0 0 0 0 Q9HCZ1 ZN334_HUMAN Zinc finger protein 334 ZNF334 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.94595 -1.3436 TYRRLWTLTEHQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5989 0 0 0 0 Q9HD23 MRS2_HUMAN "Magnesium transporter MRS2 homolog, mitochondrial (MRS2-like protein)" MRS2 HPT MRS2L Homo sapiens (Human) mitochondrial magnesium ion transmembrane transport [GO:0045016]; transmembrane transport [GO:0055085] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] magnesium ion transmembrane transporter activity [GO:0015095] 0.96914 -4.8333 AMRLPRR 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8277 0 0 0 0 0 0 0 0 0 0 0 9.74416 10.0995 Q9HD26 GOPC_HUMAN Golgi-associated PDZ and coiled-coil motif-containing protein (CFTR-associated ligand) (Fused in glioblastoma) (PDZ protein interacting specifically with TC10) (PIST) GOPC CAL FIG Homo sapiens (Human) apical protein localization [GO:0045176]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein transport [GO:0015031] cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle membrane [GO:0030660]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140] identical protein binding [GO:0042802]; molecular sequestering activity [GO:0140313]; transmembrane transporter binding [GO:0044325] 0.42291 0.666 ELEANKKEK 0 0 11.1206 11.3664 0 0 0 10.9707 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.57684 0 0 0 Q9HD34 LYRM4_HUMAN LYR motif-containing protein 4 LYRM4 C6orf149 ISD11 CGI-203 Homo sapiens (Human) [2Fe-2S] cluster assembly [GO:0044571]; [4Fe-4S] cluster assembly [GO:0044572]; iron-sulfur cluster assembly [GO:0016226] iron-sulfur cluster assembly complex [GO:1990229]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial iron-sulfur cluster assembly complex [GO:0099128]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear body [GO:0016604] protein homodimerization activity [GO:0042803] 0.89593 -0.54242 DAFRENKNVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.118 9.67076 0 0 0 0 0 Q9HD40 SPCS_HUMAN O-phosphoseryl-tRNA(Sec) selenium transferase (EC 2.9.1.2) (Liver-pancreas antigen) (LP) (SLA-p35) (SLA/LP autoantigen) (Selenocysteine synthase) (Sec synthase) (Selenocysteinyl-tRNA(Sec) synthase) (Sep-tRNA:Sec-tRNA synthase) (SepSecS) (Soluble liver antigen) (SLA) (UGA suppressor tRNA-associated protein) (tRNA(Ser/Sec)-associated antigenic protein) SEPSECS TRNP48 Homo sapiens (Human) conversion of seryl-tRNAsec to selenocys-tRNAsec [GO:0001717]; selenocysteine incorporation [GO:0001514] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] phosphoseryl-selenocysteinyl-tRNA selenium transferase activity [GO:0098621]; tRNA binding [GO:0000049] 0.90726 -0.73798 ERSKESDDNYDK 0 0 0 0 0 0 0 0 0 0 0 10.0962 8.89482 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HD43 PTPRH_HUMAN Receptor-type tyrosine-protein phosphatase H (R-PTP-H) (EC 3.1.3.48) (Stomach cancer-associated protein tyrosine phosphatase 1) (SAP-1) (Transmembrane-type protein-tyrosine phosphatase type H) PTPRH SAP1 Homo sapiens (Human) apoptotic process [GO:0006915]; protein dephosphorylation [GO:0006470] apical plasma membrane [GO:0016324]; cytoplasm [GO:0005737]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886] cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001] 0.91669 -0.84342 KQQKPELR 0 0 0 0 8.60207 8.81179 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9HD45 TM9S3_HUMAN Transmembrane 9 superfamily member 3 (EP70-P-iso) (SM-11044-binding protein) TM9SF3 SMBP UNQ245/PRO282 Homo sapiens (Human) protein localization to membrane [GO:0072657] membrane [GO:0016020] 0.9053 -0.71336 ADEHEHTYQDK 12.5744 12.7228 12.8545 0 0 0 12.1978 12.3201 12.2678 12.5529 9.1079 0 0 0 0 0 9.66878 9.71968 0 0 0 0 0 0 0 0 0 Q9HD67 MYO10_HUMAN Unconventional myosin-X (Unconventional myosin-10) MYO10 KIAA0799 Homo sapiens (Human) cytoskeleton-dependent intracellular transport [GO:0030705]; positive regulation of cell-cell adhesion [GO:0022409]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; signal transduction [GO:0007165] cell cortex [GO:0005938]; cytosol [GO:0005829]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; filopodium tip [GO:0032433]; lamellipodium [GO:0030027]; myosin complex [GO:0016459]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; ruffle [GO:0001726] "actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; microfilament motor activity [GO:0000146]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; plus-end directed microfilament motor activity [GO:0060002]; spectrin binding [GO:0030507]" 0.96249 -2.032 ENGIDIIMADR 0 0 8.88765 0 10.8455 11.0204 0 11.5829 9.90091 14.2958 10.6791 0 0 10.4721 10.4095 0 0 0 0 0 0 10.1043 0 10.2334 0 11.4582 10.8826 Q9HDB9 GAK5_HUMAN Endogenous retrovirus group K member 5 Gag polyprotein (HERV-K(II) Gag protein) (HERV-K_3q12.3 provirus ancestral Gag polyprotein) (Gag polyprotein) ERVK-5 ERVK5 Homo sapiens (Human) viral process [GO:0016032] plasma membrane [GO:0005886] nucleic acid binding [GO:0003676]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270] 0.96914 -3.97 AICLRAWGK 0 0 0 9.85797 0 8.72373 0 0 0 0 0 0 0 0 0 0 0 12.1023 0 0 0 0 0 0 0 0 10.7244 Q9HDC9 APMAP_HUMAN Adipocyte plasma membrane-associated protein (Protein BSCv) APMAP C20orf3 UNQ1869/PRO4305 Homo sapiens (Human) biosynthetic process [GO:0009058] cell surface [GO:0009986]; membrane [GO:0016020] arylesterase activity [GO:0004064]; strictosidine synthase activity [GO:0016844] 0 3.7304 EPPLLLGVLHPNTK 0 0 0 0 0 11.2617 0 0 0 0 0 0 0 0 0 0 0 0 10.8293 9.50928 9.59967 0 10.3982 9.15226 11.4098 10.1621 11.0062 Q9NNX1 TUFT1_HUMAN Tuftelin TUFT1 Homo sapiens (Human) bone mineralization [GO:0030282]; intracellular signal transduction [GO:0035556]; odontogenesis [GO:0042476] cytoplasm [GO:0005737]; extracellular region [GO:0005576] structural constituent of tooth enamel [GO:0030345] 0.92195 -1.1355 EVAGLREK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2133 Q9NNZ3 DNJC4_HUMAN DnaJ homolog subfamily C member 4 (DnaJ-like protein HSPF2) (Multiple endocrine neoplasia type 1 candidate protein number 18) DNAJC4 HSPF2 MCG18 Homo sapiens (Human) protein folding [GO:0006457]; response to unfolded protein [GO:0006986] membrane [GO:0016020] unfolded protein binding [GO:0051082] 0.90473 -0.7305 FVELSEAYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.94991 0 0 0 Q9NP50 SHCAF_HUMAN SIN3-HDAC complex-associated factor (Protein FAM60A) (Tera protein homolog) SINHCAF C12orf14 FAM60A L4 Homo sapiens (Human) negative regulation of cell differentiation [GO:0045596]; negative regulation of cell migration [GO:0030336]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of stem cell population maintenance [GO:1902459] nucleus [GO:0005634]; Sin3 complex [GO:0016580] 0.96831 -2.7781 QKICCGIIYKGR 0 0 0 9.87851 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.00214 0 0 0 0 0 0 Q9NP56 PDE7B_HUMAN "cAMP-specific 3',5'-cyclic phosphodiesterase 7B (EC 3.1.4.53)" PDE7B Homo sapiens (Human) cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; chemical synaptic transmission [GO:0007268]; signal transduction [GO:0007165] cytosol [GO:0005829]; synapse [GO:0045202] "3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]" 0.8914 -0.50406 GQTGVRAER 0 0 0 0 0 0 0 0 0 0 0 9.07791 0 0 10.161 0 0 0 0 0 0 0 0 0 0 0 0 Q9NP58 ABCB6_HUMAN ATP-binding cassette sub-family B member 6 (ABC-type heme transporter ABCB6) (EC 7.6.2.5) (Mitochondrial ABC transporter 3) (Mt-ABC transporter 3) (P-glycoprotein-related protein) (Ubiquitously-expressed mammalian ABC half transporter) ABCB6 MTABC3 PRP UMAT Homo sapiens (Human) brain development [GO:0007420]; cellular detoxification of cadmium ion [GO:0098849]; heme metabolic process [GO:0042168]; heme transmembrane transport [GO:0035351]; heme transport [GO:0015886]; intracellular copper ion homeostasis [GO:0006878]; intracellular iron ion homeostasis [GO:0006879]; melanosome assembly [GO:1903232]; porphyrin-containing compound biosynthetic process [GO:0006779]; porphyrin-containing compound metabolic process [GO:0006778]; skin development [GO:0043588]; tetrapyrrole metabolic process [GO:0033013]; transmembrane transport [GO:0055085] ATP-binding cassette (ABC) transporter complex [GO:0043190]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endolysosome membrane [GO:0036020]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; lysosomal membrane [GO:0005765]; melanosome membrane [GO:0033162]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; multivesicular body membrane [GO:0032585]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774] ABC-type heme transporter activity [GO:0015439]; ABC-type transporter activity [GO:0140359]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; efflux transmembrane transporter activity [GO:0015562]; heme binding [GO:0020037]; tetrapyrrole binding [GO:0046906] 0.92706 -1.195 AIQASLAK 0 0 9.21796 0 0 0 10.0934 0 0 0 11.6899 0 8.7211 0 0 10.2253 10.086 0 0 0 0 10.1219 10.1683 8.85209 10.1161 10.0123 0 Q9NP62 GCM1_HUMAN Chorion-specific transcription factor GCMa (hGCMa) (GCM motif protein 1) (Glial cells missing homolog 1) GCM1 GCMA Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; astrocyte fate commitment [GO:0060018]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell differentiation involved in embryonic placenta development [GO:0060706]; gliogenesis [GO:0042063]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of syncytium formation by plasma membrane fusion [GO:0060143]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell differentiation involved in embryonic placenta development [GO:0060800]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; syncytium formation by plasma membrane fusion [GO:0000768]; transcription by RNA polymerase II [GO:0006366] chromatin [GO:0000785]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone deacetylase binding [GO:0042826]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]; zinc ion binding [GO:0008270]" 0.95382 -1.5229 HIYSSEDKNAQR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.09405 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NP66 HM20A_HUMAN High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein 1) (HMG domain-containing protein HMGX1) HMG20A HMGX1 HMGXB1 Homo sapiens (Human) chromatin organization [GO:0006325]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468] nucleus [GO:0005634] DNA binding [GO:0003677]; identical protein binding [GO:0042802] 0.96398 -2.2122 ELEQYQKTEAYKVFSR 0 0 0 0 0 0 0 0 0 0 9.25753 0 0 0 0 0 0 0 0 0 0 0 0 9.63052 0 0 10.0349 Q9NP72 RAB18_HUMAN Ras-related protein Rab-18 RAB18 Homo sapiens (Human) brain development [GO:0007420]; endoplasmic reticulum tubular network organization [GO:0071786]; eye development [GO:0001654]; intracellular protein transport [GO:0006886]; lipid droplet organization [GO:0034389]; small GTPase mediated signal transduction [GO:0007264] apical plasma membrane [GO:0016324]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum tubular network [GO:0071782]; Golgi apparatus [GO:0005794]; lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667] GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.95939 -1.8846 ENREVDR 0 0 0 0 0 0 0 0 9.39556 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.29322 0 0 0 Q9NP74 PALMD_HUMAN Palmdelphin (Paralemmin-like protein) PALMD C1orf11 PALML Homo sapiens (Human) regulation of cell shape [GO:0008360] cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; membrane [GO:0016020] 0.93185 -1.2731 IEEDKLKHQHLK 0 0 0 0 0 0 0 0 0 9.24039 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NP77 SSU72_HUMAN RNA polymerase II subunit A C-terminal domain phosphatase SSU72 (CTD phosphatase SSU72) (EC 3.1.3.16) SSU72 HSPC182 PNAS-120 Homo sapiens (Human) mRNA polyadenylation [GO:0006378]; termination of RNA polymerase II transcription [GO:0006369] cytosol [GO:0005829]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleoplasm [GO:0005654] myosin phosphatase activity [GO:0017018]; RNA polymerase II CTD heptapeptide repeat phosphatase activity [GO:0008420] 0.88403 -0.12627 TTYDQMYNDLLRKDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.66991 0 0 0 0 0 0 0 Q9NP78 ABCB9_HUMAN ABC-type oligopeptide transporter ABCB9 (EC 7.4.2.6) (ATP-binding cassette sub-family B member 9) (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (hABCB9) (TAP-like protein) (TAPL) ABCB9 KIAA1520 Homo sapiens (Human) peptide metabolic process [GO:0006518]; peptide transport [GO:0015833]; protein transport [GO:0015031]; transmembrane transport [GO:0055085] endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; membrane [GO:0016020] ABC-type oligopeptide transporter activity [GO:0015421]; ABC-type peptide transporter activity [GO:0015440]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]; protein homodimerization activity [GO:0042803]; transmembrane transporter activity [GO:0022857] 0.96684 -2.8283 VAMARALVR 0 0 0 0 0 0 10.0833 0 0 0 0 0 9.85131 0 9.44611 0 0 0 0 0 0 0 0 0 0 0 0 Q9NP79 VTA1_HUMAN Vacuolar protein sorting-associated protein VTA1 homolog (Dopamine-responsive gene 1 protein) (DRG-1) (LYST-interacting protein 5) (LIP5) (SKD1-binding protein 1) (SBP1) VTA1 C6orf55 HSPC228 My012 Homo sapiens (Human) ESCRT III complex disassembly [GO:1904903]; late endosome to vacuole transport via multivesicular body sorting pathway [GO:0032511]; macroautophagy [GO:0016236]; multivesicular body assembly [GO:0036258]; multivesicular body sorting pathway [GO:0071985]; protein transport [GO:0015031] cytosol [GO:0005829]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; multivesicular body [GO:0005771]; nucleoplasm [GO:0005654] 0.0060606 2.5806 AALAPLPPLPAQFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.88756 0 0 0 0 0 0 0 0 0 0 0 Q9NP80 PLPL8_HUMAN Calcium-independent phospholipase A2-gamma (EC 3.1.1.-) (EC 3.1.1.5) (Intracellular membrane-associated calcium-independent phospholipase A2 gamma) (iPLA2-gamma) (PNPLA-gamma) (Patatin-like phospholipase domain-containing protein 8) (iPLA2-2) PNPLA8 IPLA22 IPLA2G BM-043 Homo sapiens (Human) arachidonic acid metabolic process [GO:0019369]; arachidonic acid secretion [GO:0050482]; cardiolipin metabolic process [GO:0032048]; fatty acid metabolic process [GO:0006631]; intracellular signal transduction [GO:0035556]; linoleic acid metabolic process [GO:0043651]; lipid homeostasis [GO:0055088]; phosphatidylcholine catabolic process [GO:0034638]; phosphatidylethanolamine catabolic process [GO:0046338]; prostaglandin biosynthetic process [GO:0001516]; regulation of cellular response to oxidative stress [GO:1900407]; triglyceride homeostasis [GO:0070328] endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777] ATP binding [GO:0005524]; calcium-independent phospholipase A2 activity [GO:0047499]; lysophospholipase activity [GO:0004622]; phosphatidyl phospholipase B activity [GO:0102545]; phospholipase A1 activity [GO:0008970] 0.969 -6.8749 ISHISLQRGFHTNIIR 0 0 0 10.3026 0 0 10.6696 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7587 9.63517 0 Q9NP91 S6A20_HUMAN Sodium- and chloride-dependent transporter XTRP3 (Sodium/imino-acid transporter 1) (Solute carrier family 6 member 20) (Transporter rB21A homolog) SLC6A20 SIT1 XT3 XTRP3 Homo sapiens (Human) amino acid import across plasma membrane [GO:0089718]; amino acid transport [GO:0006865]; amino-acid betaine transport [GO:0015838]; glycine import across plasma membrane [GO:1903804]; glycine transport [GO:0015816]; L-isoleucine import across plasma membrane [GO:1903806]; L-proline import across plasma membrane [GO:1904271]; proline import across plasma membrane [GO:1905647]; proline transport [GO:0015824]; sodium ion transmembrane transport [GO:0035725]; transport across blood-brain barrier [GO:0150104] apical plasma membrane [GO:0016324]; plasma membrane [GO:0005886] amino acid transmembrane transporter activity [GO:0015171]; amino-acid betaine transmembrane transporter activity [GO:0015199]; L-isoleucine transmembrane transporter activity [GO:0015188]; L-proline transmembrane transporter activity [GO:0015193]; neutral L-amino acid transmembrane transporter activity [GO:0015175]; proline:sodium symporter activity [GO:0005298]; solute:sodium symporter activity [GO:0015370] 0.87108 0.034655 GLTLHGATNGLMYMFTPK 0 0 0 0 0 11.4812 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NP92 RT30_HUMAN "Large ribosomal subunit protein mL65 (39S ribosomal protein S30, mitochondrial) (MRP-S30) (S30mt) (Large ribosomal subunit protein mS30) (Programmed cell death protein 9)" MRPS30 PDCD9 BM-047 Homo sapiens (Human) apoptotic process [GO:0006915]; mitochondrial translation [GO:0032543] mitochondrial inner membrane [GO:0005743]; mitochondrial large ribosomal subunit [GO:0005762]; mitochondrion [GO:0005739] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.96694 -2.8327 AAARCWRPLLR 0 0 0 0 0 0 0 0 9.47342 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NP94 S39A2_HUMAN Zinc transporter ZIP2 (6A1) (Eti-1) (Solute carrier family 39 member 2) (Zrt- and Irt-like protein 2) (ZIP-2) (hZIP2) SLC39A2 ZIP2 Homo sapiens (Human) cadmium ion transmembrane transport [GO:0070574]; keratinocyte differentiation [GO:0030216]; zinc ion transmembrane transport [GO:0071577]; zinc ion transport [GO:0006829] cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic vesicle [GO:0031410]; plasma membrane [GO:0005886] metal ion transmembrane transporter activity [GO:0046873]; zinc ion transmembrane transporter activity [GO:0005385] 0.93263 -1.2593 GHHRLVLR 11.39 11.357 11.3112 0 11.5853 11.669 11.7268 11.7249 11.65 11.9169 11.9151 11.8427 11.6461 0 0 0 0 0 11.4134 0 0 0 0 0 0 0 0 Q9NP98 MYOZ1_HUMAN "Myozenin-1 (Calsarcin-2) (Filamin-, actinin- and telethonin-binding protein) (Protein FATZ)" MYOZ1 MYOZ Homo sapiens (Human) myofibril assembly [GO:0030239]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of skeletal muscle tissue regeneration [GO:0043417]; negative regulation of transcription by RNA polymerase II [GO:0000122]; sarcomere organization [GO:0045214]; skeletal muscle fiber adaptation [GO:0043503]; skeletal muscle tissue development [GO:0007519]; wound healing [GO:0042060] actin cytoskeleton [GO:0015629]; nucleus [GO:0005634]; pseudopodium [GO:0031143]; Z disc [GO:0030018] actin binding [GO:0003779]; FATZ binding [GO:0051373]; protein serine/threonine phosphatase inhibitor activity [GO:0004865]; telethonin binding [GO:0031433] 0.83001 0.2046 TYISPWER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.94518 0 0 0 0 0 0 0 0 0 0 0 0 Q9NPA0 EMC7_HUMAN ER membrane protein complex subunit 7 EMC7 C11orf3 C15orf24 HT022 UNQ905/PRO1926 Homo sapiens (Human) protein insertion into ER membrane by stop-transfer membrane-anchor sequence [GO:0045050]; tail-anchored membrane protein insertion into ER membrane [GO:0071816] EMC complex [GO:0072546]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020] carbohydrate binding [GO:0030246] 0.88599 -0.36516 MRARYVNYIK 10.4441 0 8.60311 0 9.10279 0 9.54886 10.0256 8.50414 0 0 9.78979 0 0 0 0 0 0 0 10.4366 0 0 0 0 0 0 0 Q9NPA1 KCMB3_HUMAN "Calcium-activated potassium channel subunit beta-3 (BK channel subunit beta-3) (BKbeta3) (Hbeta3) (Calcium-activated potassium channel, subfamily M subunit beta-3) (Charybdotoxin receptor subunit beta-3) (K(VCA)beta-3) (Maxi K channel subunit beta-3) (Slo-beta-3)" KCNMB3 KCNMB2 KCNMBL Homo sapiens (Human) action potential [GO:0001508]; detection of calcium ion [GO:0005513]; neuronal action potential [GO:0019228]; potassium ion transport [GO:0006813] plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076] calcium-activated potassium channel activity [GO:0015269]; potassium channel regulator activity [GO:0015459] 0.8719 0.033091 VPYIEQHQFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.9074 0 0 0 Q9NPA2 MMP25_HUMAN Matrix metalloproteinase-25 (MMP-25) (EC 3.4.24.-) (Leukolysin) (Membrane-type matrix metalloproteinase 6) (MT-MMP 6) (MTMMP6) (Membrane-type-6 matrix metalloproteinase) (MT6-MMP) (MT6MMP) MMP25 MMP20 MMPL1 MT6MMP Homo sapiens (Human) collagen catabolic process [GO:0030574]; extracellular matrix organization [GO:0030198]; hard palate development [GO:0060022]; inflammatory response [GO:0006954]; proteolysis [GO:0006508] extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579] metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270] 0.77264 0.27295 DGLQQLYGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.35771 0 0 0 Q9NPA3 M1IP1_HUMAN Mid1-interacting protein 1 (Gastrulation-specific G12-like protein) (Mid1-interacting G12-like protein) (Protein STRAIT11499) (Spot 14-related protein) (S14R) (Spot 14-R) MID1IP1 MIG12 Homo sapiens (Human) lipid metabolic process [GO:0006629]; negative regulation of microtubule depolymerization [GO:0007026]; positive regulation of fatty acid biosynthetic process [GO:0045723]; positive regulation of ligase activity [GO:0051351]; protein polymerization [GO:0051258]; regulation of lipid biosynthetic process [GO:0046890] cytosol [GO:0005829]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; nucleus [GO:0005634] identical protein binding [GO:0042802] 0.91404 -0.81728 MMQICDTYNQK 0 0 0 0 0 0 0 0 0 0 12.2208 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NPB1 NT5M_HUMAN "5'(3')-deoxyribonucleotidase, mitochondrial (5',3'-nucleotidase, mitochondrial) (EC 3.1.3.-) (Deoxy-5'-nucleotidase 2) (dNT-2)" NT5M DNT2 Homo sapiens (Human) DNA replication [GO:0006260]; dUMP catabolic process [GO:0046079]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166] 0.95437 -1.528 AILDSKRPC 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.38221 0 0 0 0 0 Q9NPC2 KCNK9_HUMAN Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2) (Two pore K(+) channel KT3.2) KCNK9 TASK3 Homo sapiens (Human) potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; stabilization of membrane potential [GO:0030322] plasma membrane [GO:0005886]; synaptic vesicle [GO:0008021] potassium channel activity [GO:0005267]; potassium ion leak channel activity [GO:0022841]; voltage-gated potassium channel activity [GO:0005249] 0.92654 -1.1853 IKGKYNISSEDYR 0 0 10.487 9.82251 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NPC3 CIP1_HUMAN E3 ubiquitin-protein ligase CCNB1IP1 (EC 2.3.2.27) (Cyclin-B1-interacting protein 1) (Human enhancer of invasion 10) (RING-type E3 ubiquitin transferase CCNB1IP1) CCNB1IP1 C14orf18 HEI10 Homo sapiens (Human) blastocyst formation [GO:0001825]; chiasma assembly [GO:0051026]; protein ubiquitination [GO:0016567]; reciprocal meiotic recombination [GO:0007131]; spermatid development [GO:0007286] synaptonemal complex [GO:0000795] identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630] 0.89874 -0.57619 KVLEEYKK 10.616 0 0 0 0 9.35652 0 10.0098 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NPC6 MYOZ2_HUMAN Myozenin-2 (Calsarcin-1) (FATZ-related protein 2) MYOZ2 C4orf5 Homo sapiens (Human) negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of transcription by RNA polymerase II [GO:0000122]; sarcomere organization [GO:0045214]; skeletal muscle fiber adaptation [GO:0043503]; skeletal muscle tissue development [GO:0007519] actin cytoskeleton [GO:0015629]; sarcomere [GO:0030017]; Z disc [GO:0030018] actin binding [GO:0003779]; FATZ binding [GO:0051373]; protein phosphatase 2B binding [GO:0030346]; telethonin binding [GO:0031433] 0.73936 0.32405 SDKYTFENFQYQSRAQINHSIAMQNGK 11.312 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NPD3 EXOS4_HUMAN Exosome complex component RRP41 (Exosome component 4) (Ribosomal RNA-processing protein 41) (p12A) EXOSC4 RRP41 SKI6 Homo sapiens (Human) "defense response to virus [GO:0051607]; DNA deamination [GO:0045006]; histone mRNA catabolic process [GO:0071044]; maturation of 5.8S rRNA [GO:0000460]; nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; positive regulation of cell growth [GO:0030307]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; U4 snRNA 3'-end processing [GO:0034475]" cytoplasm [GO:0005737]; cytoplasmic exosome (RNase complex) [GO:0000177]; cytosol [GO:0005829]; euchromatin [GO:0000791]; exosome (RNase complex) [GO:0000178]; intracellular membrane-bounded organelle [GO:0043231]; nuclear exosome (RNase complex) [GO:0000176]; nucleolar exosome (RNase complex) [GO:0101019]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 3'-5'-RNA exonuclease activity [GO:0000175]; mRNA 3'-UTR AU-rich region binding [GO:0035925] 0.87379 0.036087 VLEAAAQAAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5471 0 0 0 0 0 0 10.0231 0 0 0 0 Q9NPE2 NGRN_HUMAN Neugrin (Mesenchymal stem cell protein DSC92) (Neurite outgrowth-associated protein) (Spinal cord-derived protein FI58G) NGRN FI58G HT020 Homo sapiens (Human) mitochondrial ribosome assembly [GO:0061668]; neuron differentiation [GO:0030182]; positive regulation of mitochondrial translation [GO:0070131] extracellular region [GO:0005576]; intercellular bridge [GO:0045171]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] RNA binding [GO:0003723]; rRNA binding [GO:0019843] 0.94669 -1.3492 TNTPRRR 0 12.2295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NPE6 SPAG4_HUMAN Sperm-associated antigen 4 protein (Outer dense fiber-associated protein SPAG4) (SUN domain-containing protein 4) SPAG4 SUN4 Homo sapiens (Human) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; meiotic nuclear membrane microtubule tethering complex [GO:0034993]; motile cilium [GO:0031514]; nuclear envelope [GO:0005635]; nuclear inner membrane [GO:0005637] protein-membrane adaptor activity [GO:0043495]; structural molecule activity [GO:0005198] 0.55934 0.53688 LNEDFVRKPDYALSSVGASIDLQKTSHDYADR 0 0 0 0 0 0 9.7704 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NPF0 CD320_HUMAN CD320 antigen (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6) (Transcobalamin receptor) (TCblR) (CD antigen CD320) CD320 8D6A UNQ198/PRO224 Homo sapiens (Human) B cell costimulation [GO:0031296]; cobalamin transport [GO:0015889]; positive regulation of B cell proliferation [GO:0030890]; regulation of vitamin metabolic process [GO:0030656]; ventral spinal cord development [GO:0021517] caveola [GO:0005901]; endoplasmic reticulum [GO:0005783]; membrane [GO:0016020]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; cargo receptor activity [GO:0038024]; cobalamin binding [GO:0031419]; growth factor activity [GO:0008083] 0.94643 -1.3516 LRNCSRLACLAGELR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8176 0 0 0 0 0 0 0 0 0 Q9NPF2 CHSTB_HUMAN Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) CHST11 Homo sapiens (Human) apoptotic process [GO:0006915]; carbohydrate biosynthetic process [GO:0016051]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic viscerocranium morphogenesis [GO:0048703]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; proteoglycan biosynthetic process [GO:0030166]; regulation of cell population proliferation [GO:0042127]; respiratory gaseous exchange by respiratory system [GO:0007585]; transforming growth factor beta receptor signaling pathway [GO:0007179] Golgi membrane [GO:0000139]; membrane [GO:0016020] chondroitin 4-sulfotransferase activity [GO:0047756]; N-acetylgalactosamine 4-O-sulfotransferase activity [GO:0001537]; N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity [GO:0050659]; sulfotransferase activity [GO:0008146] 0.9627 -2.4446 DQVTDTCRANSATSRK 0 0 0 0 0 0 0 0 0 9.01028 9.20401 0 0 0 0 0 11.2962 0 10.4921 0 0 0 0 0 0 0 0 Q9NPF4 OSGEP_HUMAN tRNA N6-adenosine threonylcarbamoyltransferase (EC 2.3.1.234) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (O-sialoglycoprotein endopeptidase) (hOSGEP) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEP) (tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP) OSGEP GCPL1 Homo sapiens (Human) tRNA modification [GO:0006400]; tRNA threonylcarbamoyladenosine modification [GO:0002949] cytoplasm [GO:0005737]; EKC/KEOPS complex [GO:0000408]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] "catalytic activity, acting on a tRNA [GO:0140101]; metal ion binding [GO:0046872]; N(6)-L-threonylcarbamoyladenine synthase activity [GO:0061711]" 0.39538 0.70832 LFATDER 10.0215 0 9.34924 0 0 0 8.53897 0 8.62461 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NPF5 DMAP1_HUMAN DNA methyltransferase 1-associated protein 1 (DNMAP1) (DNMT1-associated protein 1) DMAP1 KIAA1425 Homo sapiens (Human) chromatin remodeling [GO:0006338]; DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of protein import into nucleus [GO:0042307]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of DNA-templated transcription [GO:0006355]; regulation of double-strand break repair [GO:2000779]; response to ethanol [GO:0045471] cytoplasm [GO:0005737]; cytosol [GO:0005829]; NuA4 histone acetyltransferase complex [GO:0035267]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; replication fork [GO:0005657]; Swr1 complex [GO:0000812] RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription corepressor activity [GO:0003714] 0.92358 -1.0376 AVPGTDLK 0 0 0 12.2415 0 0 0 0 9.94775 0 10.9894 0 0 9.43602 9.22349 0 0 0 0 0 0 0 0 0 0 0 0 Q9NPF8 ADAP2_HUMAN Arf-GAP with dual PH domain-containing protein 2 (Centaurin-alpha-2) (Cnt-a2) ADAP2 CENTA2 Homo sapiens (Human) heart development [GO:0007507]; inositol lipid-mediated signaling [GO:0048017]; positive regulation of GTPase activity [GO:0043547]; regulation of GTPase activity [GO:0043087] cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial envelope [GO:0005740]; plasma membrane [GO:0005886] "GTPase activator activity [GO:0005096]; inositol 1,3,4,5 tetrakisphosphate binding [GO:0043533]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein-macromolecule adaptor activity [GO:0030674]" 0.97004 -4.2834 DNSQFLRRK 0 0 0 0 0 0 0 0 0 8.34465 8.56856 11.9351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NPG1 FZD3_HUMAN Frizzled-3 (Fz-3) (hFz3) FZD3 Homo sapiens (Human) "canonical Wnt signaling pathway [GO:0060070]; cell proliferation in midbrain [GO:0033278]; commissural neuron axon guidance [GO:0071679]; dopaminergic neuron axon guidance [GO:0036514]; establishment of planar polarity [GO:0001736]; hair follicle development [GO:0001942]; inner ear morphogenesis [GO:0042472]; midbrain morphogenesis [GO:1904693]; motor neuron migration [GO:0097475]; negative regulation of execution phase of apoptosis [GO:1900118]; negative regulation of mitotic cell cycle, embryonic [GO:0045976]; neural tube closure [GO:0001843]; neuron differentiation [GO:0030182]; non-canonical Wnt signaling pathway [GO:0035567]; planar cell polarity pathway involved in axon guidance [GO:1904938]; positive regulation of neuroblast proliferation [GO:0002052]; post-anal tail morphogenesis [GO:0036342]; response to electrical stimulus [GO:0051602]; response to xenobiotic stimulus [GO:0009410]; serotonergic neuron axon guidance [GO:0036515]; sympathetic ganglion development [GO:0061549]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" apical plasma membrane [GO:0016324]; axon [GO:0030424]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; filopodium tip [GO:0032433]; lateral plasma membrane [GO:0016328]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; presynaptic active zone [GO:0048786] G protein-coupled receptor activity [GO:0004930]; PDZ domain binding [GO:0030165]; Wnt receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147] 0.9208 -1.118 AGSIHSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.28186 10.2724 0 0 8.93044 9.8724 9.29214 9.44855 0 8.99856 0 0 0 Q9NPG3 UBN1_HUMAN Ubinuclein-1 (HIRA-binding protein) (Protein VT4) (Ubiquitously expressed nuclear protein) UBN1 Homo sapiens (Human) nucleosome assembly [GO:0006334] bicellular tight junction [GO:0005923]; centriolar satellite [GO:0034451]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605] DNA binding [GO:0003677] 0.9656 -2.7227 DDTYDKEK 0 0 0 0 0 0 0 0 0 0 0 10.4156 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NPG4 PCD12_HUMAN "Protocadherin-12 (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cad-2) (VE-cadherin-2) [Cleaved into: Protocadherin-12, secreted form]" PCDH12 UNQ395/PRO731 Homo sapiens (Human) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; glycogen metabolic process [GO:0005977]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; labyrinthine layer development [GO:0060711]; neuron recognition [GO:0008038] cell-cell junction [GO:0005911]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.9677 -2.9481 AYNCREAESTYRQQPK 0 0 0 0 0 0 0 0 0 0 10.2095 10.3453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NPH2 INO1_HUMAN Inositol-3-phosphate synthase 1 (IPS 1) (EC 5.5.1.4) (Myo-inositol 1-phosphate synthase) (MI-1-P synthase) (MIP synthase) (hIPS) (Myo-inositol 1-phosphate synthase A1) (hINO1) ISYNA1 INO1 Homo sapiens (Human) inositol biosynthetic process [GO:0006021]; phospholipid biosynthetic process [GO:0008654] cytoplasm [GO:0005737]; cytosol [GO:0005829] inositol-3-phosphate synthase activity [GO:0004512] 0.95464 -1.5116 DFRSSAGLDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2166 0 0 0 0 0 0 0 0 0 0 Q9NPH6 OBP2B_HUMAN Odorant-binding protein 2b (Odorant-binding protein IIb) (OBPIIb) OBP2B UNQ653/PRO1283 Homo sapiens (Human) chemosensory behavior [GO:0007635]; sensory perception of smell [GO:0007608] extracellular space [GO:0005615] odorant binding [GO:0005549]; small molecule binding [GO:0036094] 0.89827 -0.56805 VTALGGGK 9.53827 0 9.04316 0 0 0 9.35749 9.38862 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NPI5 NRK2_HUMAN Nicotinamide riboside kinase 2 (NRK 2) (NmR-K 2) (EC 2.7.1.22) (Integrin beta-1-binding protein 3) (Muscle integrin-binding protein) (MIBP) (Nicotinic acid riboside kinase 2) (EC 2.7.1.173) (Ribosylnicotinamide kinase 2) (RNK 2) (Ribosylnicotinic acid kinase 2) NMRK2 ITGB1BP3 NRK2 Homo sapiens (Human) NAD biosynthetic process [GO:0009435]; NAD metabolic process [GO:0019674]; negative regulation of myoblast differentiation [GO:0045662]; phosphorylation [GO:0016310] cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribosylnicotinamide kinase activity [GO:0050262]; ribosylnicotinate kinase activity [GO:0061769] 0.76886 0.26876 LIVGIGGMTNGGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.92665 0 0 0 0 Q9NPJ4 PNRC2_HUMAN Proline-rich nuclear receptor coactivator 2 PNRC2 HSPC208 Homo sapiens (Human) "deadenylation-independent decapping of nuclear-transcribed mRNA [GO:0031087]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]" cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932] 0.9527 -1.4921 NQQQLNRQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7231 0 0 Q9NPJ8 NXT2_HUMAN NTF2-related export protein 2 (Protein p15-2) NXT2 BM-025 DC9 Homo sapiens (Human) mRNA export from nucleus [GO:0006406]; protein import into nucleus [GO:0006606] cytosol [GO:0005829]; nuclear pore central transport channel [GO:0044613]; nuclear RNA export factor complex [GO:0042272]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] 0.88922 -0.42328 ATSLDFK 0 0 0 0 0 0 0 0 0 8.79302 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NPL8 TIDC1_HUMAN "Complex I assembly factor TIMMDC1, mitochondrial (Protein M5-14) (Translocase of inner mitochondrial membrane domain-containing protein 1) (TIMM domain containing-protein 1)" TIMMDC1 C3orf1 UNQ247/PRO284 Homo sapiens (Human) mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654] 0.95627 -1.5914 ELFGKDEQQR 0 0 0 0 10.5858 0 0 0 0 0 0 0 0 0 8.87458 0 0 0 0 0 0 0 0 0 0 0 0 Q9NPR9 GP108_HUMAN Protein GPR108 (Lung seven transmembrane receptor 2) GPR108 LUSTR2 Homo sapiens (Human) negative regulation of toll-like receptor signaling pathway [GO:0034122]; regulation of immune response [GO:0050776] cis-Golgi network membrane [GO:0033106]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; trans-Golgi network [GO:0005802] 0.93253 -1.2629 EHPFDITVMIR 0 0 0 9.68752 0 0 0 0 0 0 9.14425 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NPY3 C1QR1_HUMAN Complement component C1q receptor (C1q/MBL/SPA receptor) (C1qR) (C1qR(p)) (C1qRp) (CDw93) (Complement component 1 q subcomponent receptor 1) (Matrix-remodeling-associated protein 4) (CD antigen CD93) CD93 C1QR1 MXRA4 Homo sapiens (Human) cell-cell adhesion [GO:0098609]; macrophage activation [GO:0042116]; phagocytosis [GO:0006909] cell surface [GO:0009986]; ficolin-1-rich granule membrane [GO:0101003]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821] calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q complex binding [GO:0001849]; signaling receptor activity [GO:0038023] 0.67419 0.39371 GPEGTPK 0 0 0 0 0 0 0 0 0 0 8.33445 0 0 0 0 0 0 0 0 0 0 0 8.58064 8.30278 0 0 0 Q9NQ11 AT132_HUMAN Polyamine-transporting ATPase 13A2 (EC 7.6.2.-) ATP13A2 PARK9 Homo sapiens (Human) autophagosome organization [GO:1905037]; autophagosome-lysosome fusion [GO:0061909]; autophagy [GO:0006914]; cellular response to manganese ion [GO:0071287]; cellular response to oxidative stress [GO:0034599]; cellular response to zinc ion [GO:0071294]; extracellular exosome biogenesis [GO:0097734]; intracellular calcium ion homeostasis [GO:0006874]; intracellular iron ion homeostasis [GO:0006879]; intracellular monoatomic cation homeostasis [GO:0030003]; intracellular zinc ion homeostasis [GO:0006882]; lipid homeostasis [GO:0055088]; lysosomal transport [GO:0007041]; monoatomic ion transmembrane transport [GO:0034220]; negative regulation of lysosomal protein catabolic process [GO:1905166]; negative regulation of neuron death [GO:1901215]; peptidyl-aspartic acid autophosphorylation [GO:1990938]; polyamine transmembrane transport [GO:1902047]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein autophosphorylation [GO:0046777]; protein localization to lysosome [GO:0061462]; regulation of autophagosome size [GO:0016243]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of chaperone-mediated autophagy [GO:1904714]; regulation of endopeptidase activity [GO:0052548]; regulation of glucosylceramidase activity [GO:1905123]; regulation of intracellular protein transport [GO:0033157]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of mitochondrion organization [GO:0010821]; regulation of neuron apoptotic process [GO:0043523]; regulation of protein localization to nucleus [GO:1900180]; regulation of ubiquitin-specific protease activity [GO:2000152]; spermine transmembrane transport [GO:1903710]; transmembrane transport [GO:0055085] autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; membrane [GO:0016020]; multivesicular body [GO:0005771]; multivesicular body membrane [GO:0032585]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; transport vesicle [GO:0030133]; vesicle [GO:0031982] "ABC-type polyamine transporter activity [GO:0015417]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled monoatomic cation transmembrane transporter activity [GO:0019829]; cupric ion binding [GO:1903135]; manganese ion binding [GO:0030145]; P-type transmembrane transporter activity [GO:0140358]; phosphatidic acid binding [GO:0070300]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; polyamine transmembrane transporter activity [GO:0015203]; zinc ion binding [GO:0008270]" 0.92124 -1.1061 FPFSSALQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6998 0 0 0 0 0 0 0 0 0 Q9NQ29 LUC7L_HUMAN Putative RNA-binding protein Luc7-like 1 (Putative SR protein LUC7B1) (SR+89) LUC7L LUC7L1 Homo sapiens (Human) mRNA splice site selection [GO:0006376]; negative regulation of striated muscle tissue development [GO:0045843] U1 snRNP [GO:0005685]; U2-type prespliceosome [GO:0071004] identical protein binding [GO:0042802]; mRNA binding [GO:0003729]; RS domain binding [GO:0050733] 0.93297 -1.2785 TVAEKQEKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.231 0 0 0 0 0 0 0 0 0 Q9NQ34 TMM9B_HUMAN Transmembrane protein 9B TMEM9B C11orf15 UNQ712/PRO1375 Homo sapiens (Human) positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123] early endosome membrane [GO:0031901]; lysosomal membrane [GO:0005765] 0.95813 -1.6719 CKCICPPYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.001 0 0 0 Q9NQ36 SCUB2_HUMAN "Signal peptide, CUB and EGF-like domain-containing protein 2 (Protein CEGP1) (Scube/You)" SCUBE2 CEGP1 Homo sapiens (Human) signal transduction [GO:0007165] cell surface [GO:0009986]; extracellular region [GO:0005576]; extracellular space [GO:0005615] calcium ion binding [GO:0005509]; lipid binding [GO:0008289] 0.93285 -1.2849 LNEGKCSLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.99803 Q9NQ38 ISK5_HUMAN Serine protease inhibitor Kazal-type 5 (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Cleaved into: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665] SPINK5 Homo sapiens (Human) cell differentiation [GO:0030154]; central nervous system development [GO:0007417]; epidermal cell differentiation [GO:0009913]; epithelial cell differentiation [GO:0030855]; extracellular matrix organization [GO:0030198]; hair cell differentiation [GO:0035315]; negative regulation of angiogenesis [GO:0016525]; negative regulation of antibacterial peptide production [GO:0002787]; negative regulation of immune response [GO:0050777]; negative regulation of serine-type endopeptidase activity [GO:1900004]; negative regulation of serine-type peptidase activity [GO:1902572]; regulation of cell adhesion [GO:0030155]; regulation of T cell differentiation [GO:0045580]; regulation of timing of anagen [GO:0051884] cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; epidermal lamellar body [GO:0097209]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; perinuclear region of cytoplasm [GO:0048471] serine-type endopeptidase inhibitor activity [GO:0004867] 0.96883 -8.362 AVFQKENEER 0 0 0 0 0 0 10.0024 9.07625 0 0 0 0 8.66548 9.87549 0 0 10.0991 0 0 0 10.3041 10.0612 0 0 0 0 0 Q9NQ39 RS10L_HUMAN Putative ribosomal protein eS10-like (Putative 40S ribosomal protein S10-like) RPS10P5 RPS10L Homo sapiens (Human) cytosolic small ribosomal subunit [GO:0022627] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.0099256 1.8427 AEAGAGSATEFQFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.85613 9.31809 0 0 0 0 0 0 10.297 9.80766 9.91752 Q9NQ48 LZTL1_HUMAN Leucine zipper transcription factor-like protein 1 LZTFL1 Homo sapiens (Human) flagellated sperm motility [GO:0030317]; negative regulation of protein localization to ciliary membrane [GO:1903568]; negative regulation of protein localization to cilium [GO:1903565]; spermatogenesis [GO:0007283] cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; manchette [GO:0002177] BBSome binding [GO:0062063]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877] 0.89887 -0.61394 LAPLNEGGTAELLNK 0 0 0 9.29843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NQ55 SSF1_HUMAN Suppressor of SWI4 1 homolog (Ssf-1) (Brix domain-containing protein 3) (Peter Pan homolog) PPAN BXDC3 SSF1 Homo sapiens (Human) ribosomal large subunit assembly [GO:0000027]; rRNA processing [GO:0006364] "nucleolus [GO:0005730]; nucleus [GO:0005634]; preribosome, large subunit precursor [GO:0030687]" RNA binding [GO:0003723]; rRNA binding [GO:0019843] 0.9232 -1.0758 GNMRAQQSAVR 10.4592 10.2919 10.3859 0 0 0 0 10.5022 10.5809 11.642 11.7137 11.5563 0 0 0 11.8834 0 0 0 0 0 10.0153 0 10.1975 0 0 0 Q9NQ66 PLCB1_HUMAN "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-I) (PLC-I) (Phospholipase C-beta-1) (PLC-beta-1)" PLCB1 KIAA0581 Homo sapiens (Human) "activation of meiosis involved in egg activation [GO:0060466]; cellular response to fluoride [GO:1902618]; cellular response to glyceraldehyde [GO:1905631]; cellular response to ionomycin [GO:1904637]; cellular response to vasopressin [GO:1904117]; cerebral cortex development [GO:0021987]; fat cell differentiation [GO:0045444]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor signaling pathway [GO:0007186]; G2/M transition of mitotic cell cycle [GO:0000086]; glutamate receptor signaling pathway [GO:0007215]; inositol trisphosphate metabolic process [GO:0032957]; insulin-like growth factor receptor signaling pathway [GO:0048009]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-15-mediated signaling pathway [GO:0035723]; ion channel modulating, G protein-coupled receptor signaling pathway [GO:0099105]; learning [GO:0007612]; ligand-gated ion channel signaling pathway [GO:1990806]; memory [GO:0007613]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of monocyte extravasation [GO:2000438]; phosphatidylinositol catabolic process [GO:0031161]; phosphatidylinositol metabolic process [GO:0046488]; phosphatidylinositol-mediated signaling [GO:0048015]; phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway [GO:0007207]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of CD24 production [GO:2000560]; positive regulation of developmental growth [GO:0048639]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of embryonic development [GO:0040019]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of insulin secretion [GO:0032024]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of JNK cascade [GO:0046330]; positive regulation of myoblast differentiation [GO:0045663]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fertilization [GO:0080154]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; regulation of retrograde trans-synaptic signaling by endocanabinoid [GO:0099178]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]" chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; nuclear membrane [GO:0031965]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; protein-containing complex [GO:0032991] "calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; channel activator activity [GO:0099103]; enzyme binding [GO:0019899]; GTPase activator activity [GO:0005096]; identical protein binding [GO:0042802]; ion channel regulator activity involved in G protein-coupled receptor signaling pathway [GO:0099107]; lamin binding [GO:0005521]; phosphatidylinositol phospholipase C activity [GO:0004435]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipase C activity [GO:0004629]; protein serine/threonine kinase activator activity [GO:0043539]" 0.95203 -1.4451 DKSQMEEEK 0 10.3939 10.1799 0 0 0 8.78555 0 0 0 0 0 0 0 0 0 0 0 0 0 9.90376 0 0 0 0 0 0 Q9NQ69 LHX9_HUMAN LIM/homeobox protein Lhx9 (LIM homeobox protein 9) LHX9 Homo sapiens (Human) cell population proliferation [GO:0008283]; dorsal spinal cord interneuron anterior axon guidance [GO:0097380]; female gonad development [GO:0008585]; gonad morphogenesis [GO:0035262]; male gonad development [GO:0008584]; negative regulation of DNA-templated transcription [GO:0045892]; neuron differentiation [GO:0030182]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.68661 0.38826 GAQLNGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5051 0 0 0 0 0 0 0 0 0 Q9NQ75 CASS4_HUMAN Cas scaffolding protein family member 4 (HEF-like protein) (HEF1-EFS-p130Cas-like protein) (HEPL) CASS4 C20orf32 HEFL Homo sapiens (Human) actin filament reorganization [GO:0090527]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925] protein tyrosine kinase binding [GO:1990782] 0.73088 0.33504 LLFKRNCEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1688 Q9NQ76 MEPE_HUMAN Matrix extracellular phosphoglycoprotein (Osteoblast/osteocyte factor 45) (OF45) (Osteoregulin) MEPE Homo sapiens (Human) biomineral tissue development [GO:0031214]; skeletal system development [GO:0001501] endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576] extracellular matrix protein binding [GO:1990430]; extracellular matrix structural constituent [GO:0005201] 0.96301 -2.1235 SQNYFTNRQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.70499 0 0 0 0 0 0 Q9NQ79 CRAC1_HUMAN Cartilage acidic protein 1 (68 kDa chondrocyte-expressed protein) (CEP-68) (ASPIC) CRTAC1 ASPIC1 CEP68 Homo sapiens (Human) axonal fasciculation [GO:0007413] extracellular exosome [GO:0070062] calcium ion binding [GO:0005509] 0.87112 0.064549 NNRWEDILSDEVNVAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3287 0 0 Q9NQ87 HEYL_HUMAN Hairy/enhancer-of-split related with YRPW motif-like protein (hHeyL) (Class B basic helix-loop-helix protein 33) (bHLHb33) (Hairy-related transcription factor 3) (HRT-3) (hHRT3) HEYL BHLHB33 HRT3 Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; aortic valve morphogenesis [GO:0003180]; atrioventricular valve morphogenesis [GO:0003181]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac ventricle morphogenesis [GO:0003208]; cellular response to BMP stimulus [GO:0071773]; circulatory system development [GO:0072359]; endocardial cushion morphogenesis [GO:0003203]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; glomerulus development [GO:0032835]; mesenchymal cell development [GO:0014031]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; outflow tract morphogenesis [GO:0003151]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of neurogenesis [GO:0050767]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal muscle cell differentiation [GO:0035914]; ventricular septum morphogenesis [GO:0060412] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "AF-1 domain binding [GO:0050683]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.76183 0.29616 YLGVLEGPSSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.83518 10.289 0 0 0 0 Q9NQ89 CL004_HUMAN Protein C12orf4 C12orf4 Homo sapiens (Human) regulation of mast cell degranulation [GO:0043304] cytoplasm [GO:0005737] 0.64097 0.39659 LKESLDSGNQNGGNDDKTK 0 0 0 0 0 11.4841 0 12.5848 11.6719 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NQ90 ANO2_HUMAN Anoctamin-2 (Transmembrane protein 16B) ANO2 C12orf3 TMEM16B Homo sapiens (Human) chloride transmembrane transport [GO:1902476]; monoatomic ion transmembrane transport [GO:0034220] chloride channel complex [GO:0034707]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] chloride channel activity [GO:0005254]; intracellular calcium activated chloride channel activity [GO:0005229]; protein dimerization activity [GO:0046983] 0.86247 0.087574 LLYQEWAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.65778 0 0 0 0 0 0 0 0 0 9.31701 0 0 Q9NQ94 A1CF_HUMAN APOBEC1 complementation factor (APOBEC1-stimulating protein) A1CF ACF ASP Homo sapiens (Human) "cytidine to uridine editing [GO:0016554]; embryo implantation [GO:0007566]; mRNA localization resulting in post-transcriptional regulation of gene expression [GO:0010609]; mRNA modification [GO:0016556]; mRNA processing [GO:0006397]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; positive regulation of DNA demethylation [GO:1901537]; protein stabilization [GO:0050821]" apolipoprotein B mRNA editing enzyme complex [GO:0030895]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mRNA editing complex [GO:0045293]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] enzyme-substrate adaptor activity [GO:0140767]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727] 0.54479 0.57009 GYAFVTFSNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.62154 9.67934 0 10.4735 10.746 10.2853 0 0 0 Q9NQA5 TRPV5_HUMAN Transient receptor potential cation channel subfamily V member 5 (TrpV5) (Calcium transport protein 2) (CaT2) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Osm-9-like TRP channel 3) (OTRPC3) TRPV5 ECAC1 Homo sapiens (Human) calcium ion homeostasis [GO:0055074]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; protein homotetramerization [GO:0051289]; regulation of urine volume [GO:0035809] apical plasma membrane [GO:0016324]; plasma membrane [GO:0005886] calcium channel activity [GO:0005262]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872] 0.4016 0.70353 AEGPGSQLQK 0 0 0 0 0 0 0 0 0 0 0 12.1156 0 0 0 0 0 0 10.1298 0 0 0 0 9.86341 11.4335 0 0 Q9NQB0 TF7L2_HUMAN Transcription factor 7-like 2 (HMG box transcription factor 4) (T-cell-specific transcription factor 4) (T-cell factor 4) (TCF-4) (hTCF-4) TCF7L2 TCF4 Homo sapiens (Human) blood vessel development [GO:0001568]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition [GO:0044334]; fat cell differentiation [GO:0045444]; glucose homeostasis [GO:0042593]; maintenance of DNA repeat elements [GO:0043570]; myoblast fate commitment [GO:0048625]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type B pancreatic cell apoptotic process [GO:2000675]; pancreas development [GO:0031016]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of heparan sulfate proteoglycan biosynthetic process [GO:0010909]; positive regulation of insulin secretion [GO:0032024]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of hormone metabolic process [GO:0032350]; regulation of smooth muscle cell proliferation [GO:0048660]; regulation of transcription by RNA polymerase II [GO:0006357]; response to glucose [GO:0009749] beta-catenin-TCF complex [GO:1990907]; beta-catenin-TCF7L2 complex [GO:0070369]; catenin-TCF7L2 complex [GO:0071664]; chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-DNA complex [GO:0032993] "armadillo repeat domain binding [GO:0070016]; beta-catenin binding [GO:0008013]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; gamma-catenin binding [GO:0045295]; molecular adaptor activity [GO:0060090]; nuclear receptor binding [GO:0016922]; nucleic acid binding [GO:0003676]; protein kinase binding [GO:0019901]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific DNA binding [GO:0043565]; transcription cis-regulatory region binding [GO:0000976]" 0.88365 -0.12274 ESLEEAAKRQDGGLFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5675 0 0 Q9NQC3 RTN4_HUMAN Reticulon-4 (Foocen) (Neurite outgrowth inhibitor) (Nogo protein) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5) RTN4 KIAA0886 NOGO My043 SP1507 Homo sapiens (Human) apoptotic process [GO:0006915]; axonal fasciculation [GO:0007413]; blastocyst formation [GO:0001825]; brain development [GO:0007420]; cardiac epithelial to mesenchymal transition [GO:0060317]; cell adhesion involved in sprouting angiogenesis [GO:0120078]; cell migration involved in vasculogenesis [GO:0035441]; cellular response to hypoxia [GO:0071456]; central nervous system vasculogenesis [GO:0022009]; cerebral cortex radial glia-guided migration [GO:0021801]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum tubular network formation [GO:0071787]; endoplasmic reticulum tubular network membrane organization [GO:1990809]; endoplasmic reticulum tubular network organization [GO:0071786]; intracellular sphingolipid homeostasis [GO:0090156]; leukocyte migration involved in inflammatory response [GO:0002523]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of axon extension [GO:0030517]; negative regulation of cell growth [GO:0030308]; negative regulation of vasculogenesis [GO:2001213]; neuron differentiation [GO:0030182]; nuclear pore complex assembly [GO:0051292]; positive regulation of angiogenesis [GO:0045766]; positive regulation of artery morphogenesis [GO:1905653]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERBB3 signaling pathway [GO:1905580]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of macrophage migration [GO:1905523]; positive regulation of mammary gland epithelial cell proliferation [GO:0033601]; positive regulation of neutrophil migration [GO:1902624]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to endoplasmic reticulum [GO:1905552]; positive regulation of Rac protein signal transduction [GO:0035022]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein localization to lysosome [GO:0061462]; protein stabilization [GO:0050821]; regulation of apoptotic process [GO:0042981]; regulation of branching morphogenesis of a nerve [GO:2000172]; regulation of cell migration [GO:0030334] anchoring junction [GO:0070161]; cell junction [GO:0030054]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum tubular network [GO:0071782]; endoplasmic reticulum tubular network membrane [GO:0098826]; glutamatergic synapse [GO:0098978]; neuron projection [GO:0043005]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] cadherin binding [GO:0045296]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625] 0 2.822 AESAVIVANPR 9.76434 9.4761 9.72884 0 0 0 9.64893 9.94319 10.055 10.0673 0 9.57162 0 0 0 0 0 0 0 9.67101 8.79802 8.70186 0 9.01483 9.21318 9.42322 10.0342 Q9NQC7 CYLD_HUMAN Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD) CYLD CYLD1 KIAA0849 HSPC057 Homo sapiens (Human) cell cycle [GO:0007049]; innate immune response [GO:0045087]; necroptotic process [GO:0070266]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-18-mediated signaling pathway [GO:2000493]; negative regulation of JNK cascade [GO:0046329]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of type I interferon production [GO:0032480]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; protein deubiquitination [GO:0016579]; protein K63-linked deubiquitination [GO:0070536]; protein linear deubiquitination [GO:1990108]; regulation of cilium assembly [GO:1902017]; regulation of inflammatory response [GO:0050727]; regulation of intrinsic apoptotic signaling pathway [GO:2001242]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of mitotic cell cycle [GO:0007346]; regulation of necroptotic process [GO:0060544]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055] centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary tip [GO:0097542]; cytosol [GO:0005829]; microtubule [GO:0005874]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; spindle [GO:0005819] cysteine-type deubiquitinase activity [GO:0004843]; K63-linked deubiquitinase activity [GO:0061578]; Met1-linked polyubiquitin deubiquitinase activity [GO:0061815]; proline-rich region binding [GO:0070064]; protein kinase binding [GO:0019901]; zinc ion binding [GO:0008270] 0.95928 -1.8425 DLPDWDWR 0 0 0 0 0 0 0 12.3524 8.86669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NQC8 IFT46_HUMAN Intraflagellar transport protein 46 homolog IFT46 C11orf2 C11orf60 Homo sapiens (Human) cilium assembly [GO:0060271]; intraciliary anterograde transport [GO:0035720]; intraciliary transport [GO:0042073]; protein stabilization [GO:0050821] centrosome [GO:0005813]; ciliary tip [GO:0097542]; cilium [GO:0005929]; cytoplasm [GO:0005737]; intraciliary transport particle B [GO:0030992]; motile cilium [GO:0031514] 0.61279 0.42098 ELFQYISR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2881 0 0 0 0 Q9NQG6 MID51_HUMAN Mitochondrial dynamics protein MIEF1 (Mitochondrial dynamics protein of 51 kDa) (Mitochondrial elongation factor 1) (Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like) (SMCR7-like protein) MIEF1 MID51 SMCR7L Homo sapiens (Human) cellular response to hypoxia [GO:0071456]; mitochondrial fission [GO:0000266]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of protein targeting to membrane [GO:0090314] mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739] ADP binding [GO:0043531]; GDP binding [GO:0019003]; identical protein binding [GO:0042802] 0.2486 0.8497 AGAGERK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.88993 0 0 0 0 0 Q9NQG7 HPS4_HUMAN BLOC-3 complex member HPS4 (Hermansky-Pudlak syndrome 4 protein) (Light-ear protein homolog) HPS4 KIAA1667 Homo sapiens (Human) blood coagulation [GO:0007596]; hemostasis [GO:0007599]; intracellular transport [GO:0046907]; lysosome organization [GO:0007040]; melanocyte differentiation [GO:0030318]; melanosome assembly [GO:1903232]; platelet dense granule organization [GO:0060155]; positive regulation of eye pigmentation [GO:0048075]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein stabilization [GO:0050821]; protein targeting [GO:0006605]; vesicle-mediated transport [GO:0016192] BLOC-3 complex [GO:0031085]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane [GO:0016020]; platelet dense granule [GO:0042827] guanyl-nucleotide exchange factor activity [GO:0005085]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; small GTPase binding [GO:0031267] 0.95095 -1.4368 ATSTSTEAK 12.2096 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.72018 0 0 Q9NQH7 XPP3_HUMAN Xaa-Pro aminopeptidase 3 (X-Pro aminopeptidase 3) (EC 3.4.11.9) (Aminopeptidase P3) (APP3) XPNPEP3 Homo sapiens (Human) glomerular filtration [GO:0003094]; protein processing [GO:0016485]; proteolysis [GO:0006508] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739] aminopeptidase activity [GO:0004177]; manganese ion binding [GO:0030145]; metalloaminopeptidase activity [GO:0070006]; protein homodimerization activity [GO:0042803] 0.95216 -1.4468 NIKENNAFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0189 10.1473 0 0 0 0 0 0 Q9NQI0 DDX4_HUMAN Probable ATP-dependent RNA helicase DDX4 (EC 3.6.4.13) (DEAD box protein 4) (Vasa homolog) DDX4 VASA Homo sapiens (Human) cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; flagellated sperm motility [GO:0030317]; gamete generation [GO:0007276]; male meiosis I [GO:0007141]; male meiotic nuclear division [GO:0007140]; piRNA processing [GO:0034587]; retrotransposon silencing [GO:0010526]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; nucleus [GO:0005634]; P granule [GO:0043186]; perinuclear region of cytoplasm [GO:0048471]; pi-body [GO:0071546]; piP-body [GO:0071547] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; molecular condensate scaffold activity [GO:0140693]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.96866 -3.3214 LVEILRNIGDER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1857 0 0 0 0 0 0 Q9NQL2 RRAGD_HUMAN Ras-related GTP-binding protein D (Rag D) (RagD) (EC 3.6.5.-) RRAGD Homo sapiens (Human) cellular response to amino acid stimulus [GO:0071230]; cellular response to leucine [GO:0071233]; cellular response to leucine starvation [GO:1990253]; cellular response to starvation [GO:0009267]; negative regulation of autophagy [GO:0010507]; positive regulation of TOR signaling [GO:0032008]; positive regulation of TORC1 signaling [GO:1904263]; protein localization [GO:0008104] centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Gtr1-Gtr2 GTPase complex [GO:1990131]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; GTPase binding [GO:0051020]; protein heterodimerization activity [GO:0046982] 0.89057 -0.46324 AIHEVFEVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5779 0 Q9NQS3 NECT3_HUMAN Nectin-3 (CDw113) (Nectin cell adhesion molecule 3) (Poliovirus receptor-related protein 3) (CD antigen CD113) NECTIN3 PRR3 PVRL3 Homo sapiens (Human) establishment of protein localization to plasma membrane [GO:0061951]; fertilization [GO:0009566]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens morphogenesis in camera-type eye [GO:0002089]; protein localization to cell junction [GO:1902414]; retina morphogenesis in camera-type eye [GO:0060042]; viral entry into host cell [GO:0046718] adherens junction [GO:0005912]; apical junction complex [GO:0043296]; cell-cell contact zone [GO:0044291]; cell-cell junction [GO:0005911]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839] cell adhesion molecule binding [GO:0050839]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803] 0.87176 0.030667 NYIPPSDMQK 0 0 0 0 0 0 0 0 8.9143 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NQT6 FSCN3_HUMAN Fascin-3 (Testis fascin) FSCN3 Homo sapiens (Human) actin filament bundle assembly [GO:0051017]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163] actin cytoskeleton [GO:0015629]; cell projection membrane [GO:0031253]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; filopodium [GO:0030175]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; ruffle [GO:0001726] actin filament binding [GO:0051015]; protein-macromolecule adaptor activity [GO:0030674] 0.95197 -1.3922 FISVIYDGEVRAASERLNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3264 0 0 Q9NQT8 KI13B_HUMAN Kinesin-like protein KIF13B (Kinesin-like protein GAKIN) KIF13B GAKIN KIAA0639 Homo sapiens (Human) cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]; protein targeting [GO:0006605]; regulation of axonogenesis [GO:0050770]; signal transduction [GO:0007165]; T cell activation [GO:0042110] axon [GO:0030424]; cytoplasm [GO:0005737]; kinesin complex [GO:0005871]; microtubule [GO:0005874] 14-3-3 protein binding [GO:0071889]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777]; protein kinase binding [GO:0019901] 0.96878 -10.422 AEAMKSPELK 0 0 0 0 0 9.15393 0 0 0 0 11.4375 9.78635 0 9.03719 0 10.3732 9.77459 8.81051 0 9.58543 0 0 10.1803 0 0 10.9627 0 Q9NQV5 PRD11_HUMAN PR domain-containing protein 11 (EC 2.1.1.-) PRDM11 PFM8 Homo sapiens (Human) methylation [GO:0032259]; negative regulation of cell growth [GO:0030308]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of fibroblast apoptotic process [GO:2000271]; regulation of cell cycle [GO:0051726]; regulation of MAPK cascade [GO:0043408] cytosol [GO:0005829]; nucleus [GO:0005634] chromatin binding [GO:0003682]; methyltransferase activity [GO:0008168] 0.96966 -4.8787 DTSGESDVRCVNEVIPK 0 0 0 0 0 0 0 0 0 0 8.90794 0 0 9.1419 9.63711 0 0 0 0 0 0 0 0 0 0 0 0 Q9NQV8 PRDM8_HUMAN PR domain zinc finger protein 8 (EC 2.1.1.-) (PR domain-containing protein 8) PRDM8 PFM5 Homo sapiens (Human) methylation [GO:0032259]; oligodendrocyte development [GO:0014003]; regulation of DNA-templated transcription [GO:0006355] nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872]; methyltransferase activity [GO:0008168] 0.89843 -0.56805 LEGGSPAR 0 9.94159 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NQW1 SC31B_HUMAN Protein transport protein Sec31B (SEC31-like protein 2) (SEC31-related protein B) (SEC31B-1) SEC31B SEC31L2 Homo sapiens (Human) COPII-coated vesicle cargo loading [GO:0090110]; endoplasmic reticulum organization [GO:0007029]; intracellular protein transport [GO:0006886] COPII vesicle coat [GO:0030127]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; vesicle coat [GO:0030120] structural molecule activity [GO:0005198] 0.91062 -0.74713 KELPPEHQSLK 0 8.83971 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NQW5 PRDM7_HUMAN Histone-lysine N-methyltransferase PRDM7 (EC 2.1.1.-) (PR domain zinc finger protein 7) (PR domain-containing protein 7) ([histone H3]-lysine4 N-methyltransferase PRDM7) PRDM7 PFM4 Homo sapiens (Human) histone H3-K4 trimethylation [GO:0080182]; positive regulation of reciprocal meiotic recombination [GO:0010845]; regulation of DNA-templated transcription [GO:0006355] chromosome [GO:0005694]; nucleus [GO:0005634] histone H3K36 methyltransferase activity [GO:0046975]; histone H3K4 methyltransferase activity [GO:0042800]; recombination hotspot binding [GO:0010844] 0.87357 0.031827 ITEDEEAANSGYSWLITK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.385 0 0 0 0 0 0 0 0 0 0 Q9NQW6 ANLN_HUMAN Anillin ANLN Homo sapiens (Human) actomyosin contractile ring assembly [GO:0000915]; hematopoietic progenitor cell differentiation [GO:0002244]; mitotic cytokinesis [GO:0000281]; podocyte cell migration [GO:0090521]; positive regulation of bleb assembly [GO:1904172]; regulation of exit from mitosis [GO:0007096]; septin ring assembly [GO:0000921]; septin ring organization [GO:0031106] actin cytoskeleton [GO:0015629]; actomyosin contractile ring [GO:0005826]; bleb [GO:0032059]; cell cortex [GO:0005938]; cytosol [GO:0005829]; midbody [GO:0030496]; nucleoplasm [GO:0005654] actin binding [GO:0003779]; cadherin binding [GO:0045296] 0.9589 -1.7018 DPSGLDK 0 0 0 0 0 10.8411 0 0 0 0 0 0 0 0 0 0 0 10.7917 0 0 9.95642 10.2938 9.92646 0 0 0 10.05 Q9NQW7 XPP1_HUMAN "Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (X-Pro aminopeptidase 1) (X-prolyl aminopeptidase 1, soluble)" XPNPEP1 XPNPEPL XPNPEPL1 Homo sapiens (Human) bradykinin catabolic process [GO:0010815]; negative regulation of programmed cell death [GO:0043069]; proteolysis [GO:0006508] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062] aminopeptidase activity [GO:0004177]; manganese ion binding [GO:0030145]; metalloaminopeptidase activity [GO:0070006]; protein homodimerization activity [GO:0042803] 0.93986 -1.3252 DAVALCELFNWLEKEVPK 0 0 0 0 0 0 0 0 0 11.5334 0 0 11.8289 12.0034 0 11.3933 11.3995 12.5686 0 0 0 0 0 0 0 0 0 Q9NQW8 CNGB3_HUMAN Cyclic nucleotide-gated cation channel beta-3 (Cone photoreceptor cGMP-gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel beta-3) (CNG channel beta-3) CNGB3 Homo sapiens (Human) monoatomic cation transmembrane transport [GO:0098655]; monoatomic cation transport [GO:0006812]; signal transduction [GO:0007165]; visual perception [GO:0007601] intracellular cyclic nucleotide activated cation channel complex [GO:0017071]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; transmembrane transporter complex [GO:1902495] cGMP binding [GO:0030553]; intracellular cAMP-activated cation channel activity [GO:0005222]; intracellular cGMP-activated cation channel activity [GO:0005223]; protein-containing complex binding [GO:0044877] 0.85006 0.11625 ENSEGGEEEGK 0 0 0 0 0 0 0 0 9.70836 0 0 0 0 0 0 10.1528 0 0 0 0 10.0203 0 0 0 0 0 0 Q9NQX1 PRDM5_HUMAN PR domain zinc finger protein 5 (EC 2.1.1.-) (PR domain-containing protein 5) PRDM5 PFM2 Homo sapiens (Human) cellular response to leukemia inhibitory factor [GO:1990830]; chromatin organization [GO:0006325]; methylation [GO:0032259]; mitotic cell cycle [GO:0000278]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of extracellular matrix organization [GO:1903053] nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor binding [GO:0140297]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; methyltransferase activity [GO:0008168]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; transcription cis-regulatory region binding [GO:0000976]" 0.96965 -5.1197 FTRNDYLK 0 0 0 0 0 0 8.897 8.76138 0 0 0 0 0 0 0 10.7609 10.9658 0 9.65542 0 0 0 0 0 0 0 0 Q9NQX4 MYO5C_HUMAN Unconventional myosin-Vc MYO5C Homo sapiens (Human) actin filament organization [GO:0007015]; vesicle transport along actin filament [GO:0030050] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; myosin complex [GO:0016459]; vesicle [GO:0031982] actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; cytoskeletal motor activity [GO:0003774] 0.96888 -11.959 DLEEELDMKDRVIK 8.82509 11.0995 9.67035 0 0 0 0 0 0 10.7138 10.3155 0 0 0 0 12.6946 0 0 0 9.9497 0 0 0 9.91228 0 12.133 0 Q9NQX5 NPDC1_HUMAN Neural proliferation differentiation and control protein 1 (NPDC-1) NPDC1 Homo sapiens (Human) plasma membrane [GO:0005886] 0.80236 0.23982 ESGHSTPPLPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2717 0 0 0 0 0 0 0 0 Q9NQY0 BIN3_HUMAN Bridging integrator 3 BIN3 Homo sapiens (Human) actin cortical patch localization [GO:0051666]; actin filament organization [GO:0007015]; cytoskeleton-dependent cytokinesis [GO:0061640]; division septum assembly [GO:0000917]; endocytosis [GO:0006897]; myoblast migration involved in skeletal muscle regeneration [GO:0014839]; plasma membrane tubulation [GO:0097320]; protein localization [GO:0008104]; regulation of lamellipodium assembly [GO:0010591]; skeletal muscle fiber development [GO:0048741]; unidimensional cell growth [GO:0009826] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737] cytoskeletal anchor activity [GO:0008093] 0.96001 -1.7263 AQVVYYSEMHK 0 0 0 0 0 0 0 0 0 0 0 0 9.80782 0 0 0 0 0 0 9.11095 0 0 0 0 0 10.4419 10.8507 Q9NQZ2 SAS10_HUMAN Something about silencing protein 10 (Charged amino acid-rich leucine zipper 1) (CRL1) (Disrupter of silencing SAS10) (UTP3 homolog) UTP3 CRLZ1 SAS10 Homo sapiens (Human) "brain development [GO:0007420]; chromatin organization [GO:0006325]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosomal small subunit biogenesis [GO:0042274]" nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; small-subunit processome [GO:0032040] RNA binding [GO:0003723] 0.94686 -1.353 AGVKKSIK 0 0 0 0 0 0 0 0 0 0 8.84292 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NQZ5 STAR7_HUMAN "StAR-related lipid transfer protein 7, mitochondrial (Gestational trophoblastic tumor protein 1) (START domain-containing protein 7) (StARD7)" STARD7 GTT1 Homo sapiens (Human) mitochondrial outer membrane [GO:0005741] lipid binding [GO:0008289] 0.89891 -0.65697 LLAAWLAGTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4557 0 0 Q9NQZ6 ZC4H2_HUMAN Zinc finger C4H2 domain-containing protein (Hepatocellular carcinoma-associated antigen 127) ZC4H2 HCA127 KIAA1166 Homo sapiens (Human) nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; noradrenergic neuron development [GO:0003358]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of neuron differentiation [GO:0045666]; protein monoubiquitination [GO:0006513]; regulation of transcription regulatory region DNA binding [GO:2000677]; spinal cord motor neuron differentiation [GO:0021522] cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991] metal ion binding [GO:0046872] 0.51341 0.602 EHVDALR 11.326 0 0 0 0 0 0 0 0 9.83216 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NQZ7 ENTP7_HUMAN Ectonucleoside triphosphate diphosphohydrolase 7 (NTPDase 7) (EC 3.6.1.15) (Lysosomal apyrase-like protein 1) ENTPD7 LALP1 Homo sapiens (Human) CTP catabolic process [GO:0006254]; GTP metabolic process [GO:0046039]; nucleobase-containing small molecule catabolic process [GO:0034656]; regulation of immune response [GO:0050776]; T-helper 17 cell differentiation [GO:0072539]; UDP catabolic process [GO:0006256]; UTP catabolic process [GO:0046052] cytoplasmic vesicle membrane [GO:0030659]; endocytic vesicle membrane [GO:0030666]; Golgi apparatus [GO:0005794]; membrane [GO:0016020] CTPase activity [GO:0043273]; GDP phosphatase activity [GO:0004382]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; ribonucleoside triphosphate phosphatase activity [GO:0017111]; UDP phosphatase activity [GO:0045134] 0.95248 -1.4559 IFVYFWPR 0 0 0 0 0 0 0 0 0 0 9.11361 0 0 0 0 10.4574 10.4285 0 0 0 0 0 0 0 0 0 0 Q9NQZ8 ZNF71_HUMAN Endothelial zinc finger protein induced by tumor necrosis factor alpha (Zinc finger protein 71) ZNF71 EZFIT Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.80763 0.22808 AFRKTSSLTQHER 0 0 0 0 8.49825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1741 Q9NR00 TCIM_HUMAN Transcriptional and immune response regulator (Thyroid cancer protein 1) (TC-1) TCIM C8orf4 TC1 Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to heat [GO:0034605]; endothelial cell activation involved in immune response [GO:0002264]; negative regulation of apoptotic process [GO:0043066]; negative regulation of Notch signaling pathway [GO:0045746]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase C activity [GO:1900020]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of hemopoiesis [GO:1903706] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] Notch binding [GO:0005112] 0.38747 0.71296 VSPSIHGYHFDTASRK 0 0 0 0 0 0 11.1822 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NR09 BIRC6_HUMAN Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON) BIRC6 KIAA1289 Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; labyrinthine layer development [GO:0060711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of peptidase activity [GO:0010466]; positive regulation of cell population proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell population proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; spongiotrophoblast layer development [GO:0060712] cytosol [GO:0005829]; endosome [GO:0005768]; Flemming body [GO:0090543]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; nucleus [GO:0005634]; spindle pole [GO:0000922]; trans-Golgi network [GO:0005802] cysteine-type endopeptidase inhibitor activity [GO:0004869]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-protein transferase activity [GO:0004842] 0.96873 -7.9341 AEVASAVCLR 12.385 9.47927 10.8606 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.63739 0 9.98883 0 0 Q9NR12 PDLI7_HUMAN PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma) PDLIM7 ENIGMA Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell differentiation [GO:0030154]; heart development [GO:0007507]; muscle structure development [GO:0061061]; ossification [GO:0001503]; positive regulation of osteoblast differentiation [GO:0045669]; receptor-mediated endocytosis [GO:0006898] actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; cytosol [GO:0005829]; filamentous actin [GO:0031941]; focal adhesion [GO:0005925]; nucleoplasm [GO:0005654]; ruffle [GO:0001726]; stress fiber [GO:0001725]; Z disc [GO:0030018] actin binding [GO:0003779]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371] 0.81315 0.22268 CHGCDFK 0 9.91442 0 0 0 0 0 0 0 0 0 0 0 0 8.07012 0 0 0 0 0 0 0 0 0 0 0 0 Q9NR16 C163B_HUMAN Scavenger receptor cysteine-rich type 1 protein M160 (CD163 antigen-like 1) (CD antigen CD163b) CD163L1 CD163B M160 UNQ6434/PRO23202 Homo sapiens (Human) external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576] scavenger receptor activity [GO:0005044] 0.9556 -1.539 IQGRWGTVCHHK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9093 0 0 0 0 0 0 0 0 0 0 0 0 10.7618 Q9NR19 ACSA_HUMAN "Acetyl-coenzyme A synthetase, cytoplasmic (EC 6.2.1.1) (Acetate--CoA ligase) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acetyl-CoA synthetase 1) (AceCS1) (Acyl-CoA synthetase short-chain family member 2) (Acyl-activating enzyme) (Propionate--CoA ligase) (EC 6.2.1.17)" ACSS2 ACAS2 Homo sapiens (Human) acetyl-CoA biosynthetic process [GO:0006085]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; ethanol oxidation [GO:0006069]; lipid biosynthetic process [GO:0008610] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759] acetate-CoA ligase activity [GO:0003987]; AMP binding [GO:0016208]; ATP binding [GO:0005524]; propionate-CoA ligase activity [GO:0050218] 0.84357 0.13996 FETTYFKK 9.43694 9.22928 9.10489 0 0 0 0 0 0 10.5574 10.4951 10.2855 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NR20 DYRK4_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 4 (EC 2.7.12.1) DYRK4 Homo sapiens (Human) peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein tyrosine kinase activity [GO:0004713] 0.9202 -1.1433 KDKVQGCHHSSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1913 0 0 0 0 0 0 0 0 0 Q9NR21 PAR11_HUMAN Protein mono-ADP-ribosyltransferase PARP11 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 11) (ARTD11) (Poly [ADP-ribose] polymerase 11) (PARP-11) PARP11 C12orf6 Homo sapiens (Human) cell differentiation [GO:0030154]; mRNA transport [GO:0051028]; nuclear envelope organization [GO:0006998]; protein auto-ADP-ribosylation [GO:0070213]; protein transport [GO:0015031]; spermatogenesis [GO:0007283] cytosol [GO:0005829]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+- protein-cysteine ADP-ribosyltransferase activity [GO:0140803]; NAD+- protein-lysine ADP-ribosyltransferase activity [GO:0140804]; NAD+-protein ADP-ribosyltransferase activity [GO:1990404]; nucleotidyltransferase activity [GO:0016779] 0.88556 -0.29073 QMNLTTGKQR 0 0 0 0 0 0 9.80382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NR22 ANM8_HUMAN Protein arginine N-methyltransferase 8 (EC 2.1.1.319) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4) PRMT8 HRMT1L3 HRMT1L4 Homo sapiens (Human) peptidyl-arginine methylation [GO:0018216]; protein homooligomerization [GO:0051260]; protein methylation [GO:0006479]; regulation of protein binding [GO:0043393] cytoplasmic side of plasma membrane [GO:0009898]; plasma membrane [GO:0005886] enzyme binding [GO:0019899]; histone H4 methyltransferase activity [GO:0140939]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757] 0.80972 0.23361 QVVTNACLIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1038 0 0 0 0 0 0 0 0 Q9NR28 DBLOH_HUMAN "Diablo IAP-binding mitochondrial protein (Diablo homolog, mitochondrial) (Direct IAP-binding protein with low pI) (Second mitochondria-derived activator of caspase) (Smac) [Cleaved into: Diablo IAP-binding mitochondrial protein, cleaved form]" DIABLO SMAC Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; apoptotic process [GO:0006915]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; neuron apoptotic process [GO:0051402]; positive regulation of apoptotic process [GO:0043065] CD40 receptor complex [GO:0035631]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739] 0.6082 0.43105 LAEAQIEELR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0664 0 Q9NR30 DDX21_HUMAN Nucleolar RNA helicase 2 (EC 3.6.4.13) (DEAD box protein 21) (Gu-alpha) (Nucleolar RNA helicase Gu) (Nucleolar RNA helicase II) (RH II/Gu) DDX21 Homo sapiens (Human) chromatin remodeling [GO:0006338]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; osteoblast differentiation [GO:0001649]; positive regulation of histone acetylation [GO:0035066]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myeloid dendritic cell cytokine production [GO:0002735]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; R-loop processing [GO:0062176]; response to exogenous dsRNA [GO:0043330]; rRNA processing [GO:0006364]; transcription by RNA polymerase II [GO:0006366] B-WICH complex [GO:0110016]; chromosome [GO:0005694]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] 7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; rRNA binding [GO:0019843]; snoRNA binding [GO:0030515] 0.95079 -1.4006 DLIAQARTGTGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.13814 0 0 0 0 0 0 10.1053 10.1534 0 0 0 Q9NR31 SAR1A_HUMAN GTP-binding protein SAR1a (COPII-associated small GTPase) SAR1A SAR1 SARA SARA1 Homo sapiens (Human) COPII-coated vesicle cargo loading [GO:0090110]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; membrane organization [GO:0061024]; positive regulation of protein exit from endoplasmic reticulum [GO:0070863]; regulation of COPII vesicle coating [GO:0003400]; vesicle organization [GO:0016050] COPII vesicle coat [GO:0030127]; endoplasmic reticulum exit site [GO:0070971]; Golgi apparatus [GO:0005794] GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.84156 0.14731 ELNARPMEVFMCSVLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4555 0 0 0 0 0 0 0 0 0 0 0 Q9NR34 MA1C1_HUMAN "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC (EC 3.2.1.113) (HMIC) (Mannosidase alpha class 1C member 1) (Processing alpha-1,2-mannosidase IC) (Alpha-1,2-mannosidase IC)" MAN1C1 MAN1A3 MAN1C Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; Golgi apparatus mannose trimming [GO:1904381]; N-glycan processing [GO:0006491]; protein N-linked glycosylation [GO:0006487] endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139] "calcium ion binding [GO:0005509]; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [GO:0004571]" 0.89733 -0.62889 EWGWEVVLALEKYCR 9.38481 0 0 0 0 0 0 0 0 0 8.77393 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.82788 Q9NR45 SIAS_HUMAN Sialic acid synthase (N-acetylneuraminate synthase) (EC 2.5.1.56) (N-acetylneuraminate-9-phosphate synthase) (EC 2.5.1.57) (N-acetylneuraminic acid phosphate synthase) (N-acetylneuraminic acid synthase) NANS SAS Homo sapiens (Human) carbohydrate biosynthetic process [GO:0016051]; CMP-N-acetylneuraminate biosynthetic process [GO:0006055]; glycosylation [GO:0070085] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062] N-acetylneuraminate synthase activity [GO:0050462]; N-acylneuraminate cytidylyltransferase activity [GO:0008781]; N-acylneuraminate-9-phosphate synthase activity [GO:0047444] 0.92251 -1.1016 MAKECGADCAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0244 10.3802 0 0 9.11194 0 0 0 0 0 0 0 0 Q9NR46 SHLB2_HUMAN Endophilin-B2 (SH3 domain-containing GRB2-like protein B2) SH3GLB2 KIAA1848 PP578 Homo sapiens (Human) membrane organization [GO:0061024] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654] cadherin binding [GO:0045296]; identical protein binding [GO:0042802] 0.91426 -0.78154 KLASDAGIFFTR 0 0 0 0 0 0 0 0 0 0 0 0 10.5266 10.7669 10.6903 0 0 0 0 0 0 0 0 0 0 0 0 Q9NR48 ASH1L_HUMAN Histone-lysine N-methyltransferase ASH1L (EC 2.1.1.359) (EC 2.1.1.367) (ASH1-like protein) (huASH1) (Absent small and homeotic disks protein 1 homolog) (Lysine N-methyltransferase 2H) ASH1L KIAA1420 KMT2H Homo sapiens (Human) decidualization [GO:0046697]; flagellated sperm motility [GO:0030317]; histone H3-K36 dimethylation [GO:0097676]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; MAPK cascade [GO:0000165]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of MAPK cascade [GO:0043409]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; regulation of DNA-templated transcription [GO:0006355]; single fertilization [GO:0007338]; skeletal system development [GO:0001501]; tarsal gland development [GO:1903699]; transcription by RNA polymerase II [GO:0006366]; uterine gland development [GO:1903709]; uterus morphogenesis [GO:0061038] bicellular tight junction [GO:0005923]; chromosome [GO:0005694]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; histone H3K36 methyltransferase activity [GO:0046975]; histone H3K36 trimethyltransferase activity [GO:0140955]; histone H3K4 methyltransferase activity [GO:0042800]; histone H3K9 methyltransferase activity [GO:0046974]; histone H3K9 monomethyltransferase activity [GO:0140948]; histone H3K9me2 methyltransferase activity [GO:0140947]; metal ion binding [GO:0046872] 0.96819 -9.2788 AEEKGWGIR 0 0 0 9.53327 10.2897 9.09511 0 8.6709 0 0 0 11.4465 9.84123 0 0 0 0 0 0 0 0 9.86423 0 0 0 0 0 Q9NR56 MBNL1_HUMAN Muscleblind-like protein 1 (Triplet-expansion RNA-binding protein) MBNL1 EXP KIAA0428 MBNL Homo sapiens (Human) embryonic limb morphogenesis [GO:0030326]; in utero embryonic development [GO:0001701]; mRNA processing [GO:0006397]; myoblast differentiation [GO:0045445]; nervous system development [GO:0007399]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; regulatory region RNA binding [GO:0001069]; RNA binding [GO:0003723] 0.84128 0.14712 AVSVTPIR 0 17.2307 0 12.6439 14.2652 0 0 16.9828 16.99 0 10.0366 0 0 15.1046 0 0 0 0 0 14.2501 0 13.7433 0 0 0 0 14.9606 Q9NR61 DLL4_HUMAN Delta-like protein 4 (Drosophila Delta homolog 4) (Delta4) DLL4 UNQ1895/PRO4341 Homo sapiens (Human) angiogenesis [GO:0001525]; aortic valve morphogenesis [GO:0003180]; blood circulation [GO:0008015]; blood vessel lumenization [GO:0072554]; blood vessel remodeling [GO:0001974]; branching involved in blood vessel morphogenesis [GO:0001569]; cardiac atrium morphogenesis [GO:0003209]; cardiac ventricle morphogenesis [GO:0003208]; cellular response to cholesterol [GO:0071397]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to oxygen-glucose deprivation [GO:0090650]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chondrocyte differentiation [GO:0002062]; dorsal aorta morphogenesis [GO:0035912]; luteolysis [GO:0001554]; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903588]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of gene expression [GO:0010629]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; pericardium morphogenesis [GO:0003344]; positive regulation of gene expression [GO:0010628]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of Notch signaling pathway [GO:0045747]; regulation of neural retina development [GO:0061074]; regulation of neurogenesis [GO:0050767]; signal transduction [GO:0007165]; T cell differentiation [GO:0030217]; ventral spinal cord interneuron fate commitment [GO:0060579]; ventricular trabecula myocardium morphogenesis [GO:0003222]; visual perception [GO:0007601] cytoplasm [GO:0005737]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; Notch binding [GO:0005112]; receptor ligand activity [GO:0048018] 0.30464 0.80553 NECVIATEV 9.80565 9.71749 9.43215 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NR71 ASAH2_HUMAN Neutral ceramidase (N-CDase) (NCDase) (EC 3.5.1.-) (EC 3.5.1.23) (Acylsphingosine deacylase 2) (BCDase) (LCDase) (hCD) (N-acylsphingosine amidohydrolase 2) (Non-lysosomal ceramidase) [Cleaved into: Neutral ceramidase soluble form] ASAH2 HNAC1 Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to cytokine stimulus [GO:0071345]; ceramide biosynthetic process [GO:0046513]; ceramide catabolic process [GO:0046514]; ceramide metabolic process [GO:0006672]; lipid digestion [GO:0044241]; long-chain fatty acid biosynthetic process [GO:0042759]; negative regulation of apoptotic signaling pathway [GO:2001234]; regulation of mitotic cell cycle [GO:0007346]; sphingosine biosynthetic process [GO:0046512]; sphingosine metabolic process [GO:0006670] caveola [GO:0005901]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; ceramidase activity [GO:0102121]; N-acylsphingosine amidohydrolase activity [GO:0017040]; zinc ion binding [GO:0008270] 0.91502 -0.81076 LYSRAFIMAEPDGSNR 0 10.2818 0 0 0 0 0 0 0 10.5909 0 0 0 10.2459 0 0 10.5918 0 0 0 0 0 0 0 0 0 0 Q9NR80 ARHG4_HUMAN Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor 1) (Asef) (Asef1) ARHGEF4 KIAA1112 Homo sapiens (Human) filopodium assembly [GO:0046847]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; regulation of small GTPase mediated signal transduction [GO:0051056] cytosol [GO:0005829]; ruffle membrane [GO:0032587] guanyl-nucleotide exchange factor activity [GO:0005085]; protein domain specific binding [GO:0019904] 0.96153 -2.5603 VTQPQAK 0 0 0 0 0 0 9.71222 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NR81 ARHG3_HUMAN Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN) ARHGEF3 Homo sapiens (Human) positive regulation of Rho protein signal transduction [GO:0035025]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266] cytosol [GO:0005829] guanyl-nucleotide exchange factor activity [GO:0005085] 0.95983 -1.9679 ALLDHKK 14.887 15.0377 14.8156 10.3901 9.86762 10.3231 14.8656 14.7762 14.749 0 15.3902 15.0887 0 0 0 0 0 0 12.1494 12.2994 12.466 0 11.5481 0 9.85198 0 0 Q9NR82 KCNQ5_HUMAN Potassium voltage-gated channel subfamily KQT member 5 (KQT-like 5) (Potassium channel subunit alpha KvLQT5) (Voltage-gated potassium channel subunit Kv7.5) KCNQ5 Homo sapiens (Human) potassium ion transmembrane transport [GO:0071805]; regulation of monoatomic ion transmembrane transport [GO:0034765] clathrin coat [GO:0030118]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076] voltage-gated potassium channel activity [GO:0005249] 0.78628 0.25724 EAAFASDSLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.60322 0 Q9NR83 S2A4R_HUMAN SLC2A4 regulator (GLUT4 enhancer factor) (GEF) (Huntington disease gene regulatory region-binding protein 1) (HDBP-1) SLC2A4RG HDBP1 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleus [GO:0005634] DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96148 -2.5704 ATPGKAR 0 0 0 0 0 0 0 0 0 8.90557 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NR90 DAZ3_HUMAN Deleted in azoospermia protein 3 DAZ3 Homo sapiens (Human) 3'-UTR-mediated mRNA stabilization [GO:0070935]; cell differentiation [GO:0030154]; positive regulation of translational initiation [GO:0045948]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] mRNA 3'-UTR binding [GO:0003730]; translation activator activity [GO:0008494] 0.87067 0.065554 IVGSQIHFHGK 0 0 0 0 0 9.31458 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NR96 TLR9_HUMAN Toll-like receptor 9 (CD antigen CD289) TLR9 UNQ5798/PRO19605 Homo sapiens (Human) cellular response to chloroquine [GO:1902350]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to metal ion [GO:0071248]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to virus [GO:0051607]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; I-kappaB phosphorylation [GO:0007252]; innate immune response [GO:0045087]; maintenance of gastrointestinal epithelium [GO:0030277]; male gonad development [GO:0008584]; microglial cell activation [GO:0001774]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; negative regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901895]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; positive regulation of autophagy [GO:0010508]; positive regulation of B cell activation [GO:0050871]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine production [GO:0032722]; positive regulation of gene expression [GO:0010628]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-18 production [GO:0032741]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; positive regulation of toll-like receptor signaling pathway [GO:0034123]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type II interferon production [GO:0032729]; regulation of B cell differentiation [GO:0045577]; regulation of dendritic cell cytokine production [GO:0002730]; regulation of toll-like receptor 9 signaling pathway [GO:0034163]; response to molecule of bacterial origin [GO:0002237]; toll-like receptor signaling pathway [GO:0002224] apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cytoplasm [GO:0005737]; early phagosome [GO:0032009]; endolysosome [GO:0036019]; endolysosome membrane [GO:0036020]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; lysosome [GO:0005764]; plasma membrane [GO:0005886] interleukin-1 receptor binding [GO:0005149]; pattern recognition receptor activity [GO:0038187]; protein homodimerization activity [GO:0042803]; siRNA binding [GO:0035197]; unmethylated CpG binding [GO:0045322] 0.88971 -0.47101 CDHAPNPCMECPR 0 0 0 0 0 0 0 0 0 9.97097 0 9.97025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NR97 TLR8_HUMAN Toll-like receptor 8 (CD antigen CD288) TLR8 UNQ249/PRO286 Homo sapiens (Human) cellular response to mechanical stimulus [GO:0071260]; defense response to virus [GO:0051607]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immunoglobulin mediated immune response [GO:0016064]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of interleukin-12 production [GO:0032695]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of type II interferon production [GO:0032729]; regulation of protein phosphorylation [GO:0001932]; response to virus [GO:0009615]; toll-like receptor 8 signaling pathway [GO:0034158]; toll-like receptor signaling pathway [GO:0002224] endolysosome membrane [GO:0036020]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; external side of plasma membrane [GO:0009897]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886] DNA binding [GO:0003677]; double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; pattern recognition receptor activity [GO:0038187]; RNA binding [GO:0003723]; signaling receptor activity [GO:0038023]; single-stranded RNA binding [GO:0003727] 0.88559 -0.372 NVVLTENDSR 0 0 0 0 0 0 0 0 8.50906 0 0 0 0 0 0 0 8.5877 0 0 0 0 0 0 0 9.41635 9.43406 9.35045 Q9NR99 MXRA5_HUMAN Matrix-remodeling-associated protein 5 (Adhesion protein with leucine-rich repeats and immunoglobulin domains related to perlecan) (Adlican) MXRA5 Homo sapiens (Human) response to transforming growth factor beta [GO:0071559] collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576] extracellular matrix structural constituent [GO:0005201] 0.95879 -1.6973 APMDDPDSK 15.4841 8.83971 15.499 11.9407 0 11.6964 17.457 0 0 12.0635 11.9066 13.0192 0 0 0 14.8655 0 14.938 12.9135 12.4611 0 0 13.5383 0 0 0 0 Q9NRA8 4ET_HUMAN Eukaryotic translation initiation factor 4E transporter (4E-T) (eIF4E transporter) (Eukaryotic translation initiation factor 4E nuclear import factor 1) EIF4ENIF1 Homo sapiens (Human) miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; mRNA stabilization [GO:0048255]; negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0106289]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of translation [GO:0017148]; neuron differentiation [GO:0030182]; P-body assembly [GO:0033962]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; protein import into nucleus [GO:0006606]; stem cell population maintenance [GO:0019827]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; P-body [GO:0000932]; PML body [GO:0016605] kinase binding [GO:0019900]; mRNA binding [GO:0003729]; nuclear export signal receptor activity [GO:0005049]; RNA binding [GO:0003723] 0.93989 -1.3012 DSSPTTNSKLSALQR 0 0 0 0 0 0 0 0 0 10.9516 0 0 0 0 0 0 0 0 0 0 0 0 0 8.73478 0 0 0 Q9NRB3 CHSTC_HUMAN Carbohydrate sulfotransferase 12 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 2) (Chondroitin 4-sulfotransferase 2) (C4ST-2) (C4ST2) (Sulfotransferase Hlo) CHST12 UNQ500/PRO1017 Homo sapiens (Human) chondroitin sulfate biosynthetic process [GO:0030206]; dermatan sulfate biosynthetic process [GO:0030208]; proteoglycan biosynthetic process [GO:0030166] Golgi membrane [GO:0000139]; membrane [GO:0016020] 3'-phosphoadenosine 5'-phosphosulfate binding [GO:0050656]; chondroitin 4-sulfotransferase activity [GO:0047756]; sulfotransferase activity [GO:0008146] 0.93229 -1.2571 QLRFPPSYRNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1698 0 0 Q9NRC1 ST7_HUMAN Suppressor of tumorigenicity 7 protein (Protein FAM4A1) (Protein HELG) ST7 FAM4A1 HELG RAY1 Homo sapiens (Human) extracellular matrix organization [GO:0030198]; regulation of cell differentiation [GO:0045595] membrane [GO:0016020] 0.93966 -1.3032 EAVKMMRDLMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0013 0 0 0 0 0 0 0 0 0 Q9NRC6 SPTN5_HUMAN "Spectrin beta chain, non-erythrocytic 5 (Beta-V spectrin)" SPTBN5 BSPECV HUBSPECV HUSPECV Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament capping [GO:0051693]; Golgi organization [GO:0007030]; lysosomal transport [GO:0007041] apical cortex [GO:0045179]; cell junction [GO:0030054]; cell projection [GO:0042995]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; microtubule associated complex [GO:0005875]; photoreceptor connecting cilium [GO:0032391]; photoreceptor disc membrane [GO:0097381]; plasma membrane [GO:0005886]; spectrin [GO:0008091] actin binding [GO:0003779]; actin filament binding [GO:0051015]; dynactin binding [GO:0034452]; dynein intermediate chain binding [GO:0045505]; identical protein binding [GO:0042802]; kinesin binding [GO:0019894]; myosin tail binding [GO:0032029]; opsin binding [GO:0002046]; protein self-association [GO:0043621]; spectrin binding [GO:0030507] 0.96957 -3.5128 AGQPHSPR 11.3676 0 11.2019 0 0 0 11.4915 11.5191 11.5932 0 12.2987 11.9083 0 0 0 0 9.83966 0 0 0 0 12.3653 11.1945 11.4172 11.6931 0 0 Q9NRC8 SIR7_HUMAN NAD-dependent protein deacetylase sirtuin-7 (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-7) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 7) (SIR2-like protein 7) SIRT7 SIR2L7 Homo sapiens (Human) "DNA damage response [GO:0006974]; DNA repair [GO:0006281]; DNA repair-dependent chromatin remodeling [GO:0140861]; histone H3 deacetylation [GO:0070932]; homologous chromosome pairing at meiosis [GO:0007129]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of rRNA processing [GO:2000234]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription involved in exit from mitosis [GO:0007072]; protein deacetylation [GO:0006476]; protein deglutarylation [GO:0061698]; protein depropionylation [GO:0106230]; R-loop processing [GO:0062176]; regulation of DNA repair [GO:0006282]; regulation of mitochondrion organization [GO:0010821]; regulation of protein export from nucleus [GO:0046825]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901836]; retrotransposon silencing [GO:0010526]; rRNA transcription [GO:0009303]; transcription initiation-coupled chromatin remodeling [GO:0045815]" chromatin [GO:0000785]; cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleolus organizer region [GO:0005731]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861] chromatin binding [GO:0003682]; metal ion binding [GO:0046872]; NAD+ binding [GO:0070403]; NAD-dependent histone H3K18 deacetylase activity [GO:0097372]; NAD-dependent protein deacetylase activity [GO:0034979]; protein methyltransferase activity [GO:0008276]; protein-glutaryllysine deglutarylase activity [GO:0061697]; protein-propionyllysine depropionylase activity [GO:0106231]; protein-succinyllysine desuccinylase activity [GO:0036055] 0.80326 0.24073 GPNGVWTLLQK 0 0 0 0 0 0 0 0 0 0 0 11.3748 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NRD0 FBX8_HUMAN F-box only protein 8 (F-box/SEC7 protein FBS) FBXO8 FBS FBX8 DC10 UNQ1877/PRO4320 Homo sapiens (Human) regulation of ARF protein signal transduction [GO:0032012]; ubiquitin-dependent protein catabolic process [GO:0006511] ubiquitin ligase complex [GO:0000151] guanyl-nucleotide exchange factor activity [GO:0005085] 0.91446 -0.7783 QVQGGIDIYHLLKAR 0 0 0 13.2587 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NRD1 FBX6_HUMAN F-box only protein 6 (F-box protein that recognizes sugar chains 2) (F-box/G-domain protein 2) FBXO6 FBG2 FBS2 FBX6 Homo sapiens (Human) DNA damage checkpoint signaling [GO:0000077]; DNA repair [GO:0006281]; glycoprotein catabolic process [GO:0006516]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; response to unfolded protein [GO:0006986]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent ERAD pathway [GO:0030433] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum quality control compartment [GO:0044322]; SCF ubiquitin ligase complex [GO:0019005] carbohydrate binding [GO:0030246]; ubiquitin protein ligase activity [GO:0061630] 0.8133 0.22165 YILFQHGGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.31653 Q9NRD5 PICK1_HUMAN PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein) PICK1 PRKCABP Homo sapiens (Human) "cellular response to decreased oxygen levels [GO:0036294]; cellular response to glucose starvation [GO:0042149]; dendritic spine maintenance [GO:0097062]; dendritic spine organization [GO:0097061]; DNA methylation involved in embryo development [GO:0043045]; DNA methylation involved in gamete generation [GO:0043046]; glial cell development [GO:0021782]; intracellular protein transport [GO:0006886]; long-term synaptic depression [GO:0060292]; monoamine transport [GO:0015844]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; neuronal ion channel clustering [GO:0045161]; positive regulation of receptor internalization [GO:0002092]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; protein phosphorylation [GO:0006468]; receptor clustering [GO:0043113]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315]; regulation of insulin secretion [GO:0050796]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]" cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; Golgi apparatus [GO:0005794]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic early endosome [GO:0098842]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588] actin filament binding [GO:0051015]; Arp2/3 complex binding [GO:0071933]; G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; membrane curvature sensor activity [GO:0140090]; metal ion binding [GO:0046872]; phospholipid binding [GO:0005543]; protein domain specific binding [GO:0019904]; protein kinase C binding [GO:0005080]; signaling receptor binding [GO:0005102] 0.96232 -2.4854 CRQEARAR 12.8235 12.6771 12.8858 10.56 10.8409 0 12.1038 12.4083 11.275 9.59557 12.2025 9.12042 0 11.4174 0 12.2285 12.3129 11.6977 0 0 0 0 0 0 0 0 0 Q9NRD8 DUOX2_HUMAN Dual oxidase 2 (EC 1.11.1.-) (EC 1.6.3.1) (Large NOX 2) (Long NOX 2) (NADH/NADPH thyroid oxidase p138-tox) (NADPH oxidase/peroxidase DUOX2) (NADPH thyroid oxidase 2) (Thyroid oxidase 2) (p138 thyroid oxidase) DUOX2 LNOX2 THOX2 Homo sapiens (Human) cuticle development [GO:0042335]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; hormone biosynthetic process [GO:0042446]; hydrogen peroxide biosynthetic process [GO:0050665]; hydrogen peroxide catabolic process [GO:0042744]; positive regulation of cell motility [GO:2000147]; positive regulation of wound healing [GO:0090303]; response to cAMP [GO:0051591]; response to oxidative stress [GO:0006979]; response to virus [GO:0009615]; superoxide anion generation [GO:0042554]; thyroid hormone generation [GO:0006590] anchoring junction [GO:0070161]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell leading edge [GO:0031252]; cell surface [GO:0009986]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; NADPH oxidase complex [GO:0043020]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; heme binding [GO:0020037]; NAD(P)H oxidase H2O2-forming activity [GO:0016174]; NADH oxidase H202-forming activity [GO:0106293]; NADPH oxidase H202-forming activity [GO:0106294]; peroxidase activity [GO:0004601]; superoxide-generating NAD(P)H oxidase activity [GO:0016175] 0.86905 0.044415 FVENYRR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.73993 0 0 10.0501 0 8.47735 10.0755 0 0 0 0 11.007 9.89703 0 Q9NRD9 DUOX1_HUMAN Dual oxidase 1 (EC 1.11.1.-) (EC 1.6.3.1) (Large NOX 1) (Long NOX 1) (NADPH thyroid oxidase 1) (Thyroid oxidase 1) DUOX1 DUOX LNOX1 THOX1 Homo sapiens (Human) cuticle development [GO:0042335]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; hormone biosynthetic process [GO:0042446]; hydrogen peroxide biosynthetic process [GO:0050665]; hydrogen peroxide catabolic process [GO:0042744]; positive regulation of cell motility [GO:2000147]; positive regulation of wound healing [GO:0090303]; response to cAMP [GO:0051591]; response to oxidative stress [GO:0006979]; superoxide anion generation [GO:0042554]; thyroid hormone generation [GO:0006590] apical plasma membrane [GO:0016324]; cell leading edge [GO:0031252]; cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; NADPH oxidase complex [GO:0043020]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; heme binding [GO:0020037]; NAD(P)H oxidase H2O2-forming activity [GO:0016174]; NADH oxidase H202-forming activity [GO:0106293]; NADP binding [GO:0050661]; NADPH oxidase H202-forming activity [GO:0106294]; peroxidase activity [GO:0004601]; superoxide-generating NAD(P)H oxidase activity [GO:0016175] 0.96419 -2.2609 AAGPWTTRLR 0 0 0 0 0 0 0 0 0 0 0 9.7874 0 0 0 0 12.2529 0 0 0 0 0 0 0 0 0 0 Q9NRE2 TSH2_HUMAN Teashirt homolog 2 (Ovarian cancer-related protein 10-2) (OVC10-2) (Zinc finger protein 218) TSHZ2 C20orf17 TSH2 ZNF218 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]" 0.96375 -2.2231 EEDLEDGSK 0 0 0 9.06872 0 0 0 0 0 0 12.3579 10.1648 0 0 0 0 0 0 0 10.9855 0 0 0 0 0 0 0 Q9NRF2 SH2B1_HUMAN "SH2B adapter protein 1 (Pro-rich, PH and SH2 domain-containing signaling mediator) (PSM) (SH2 domain-containing protein 1B)" SH2B1 KIAA1299 SH2B Homo sapiens (Human) intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of SMAD protein signal transduction [GO:0060391]; regulation of DNA biosynthetic process [GO:2000278] cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886] transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068] 0.71226 0.36754 LSIPCSSITDVR 0 9.34119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NRF8 PYRG2_HUMAN CTP synthase 2 (EC 6.3.4.2) (CTP synthetase 2) (UTP--ammonia ligase 2) CTPS2 Homo sapiens (Human) 'de novo' CTP biosynthetic process [GO:0044210]; CTP biosynthetic process [GO:0006241]; glutamine metabolic process [GO:0006541]; pyrimidine nucleobase biosynthetic process [GO:0019856]; pyrimidine nucleotide metabolic process [GO:0006220] cytoophidium [GO:0097268]; cytoplasm [GO:0005737]; cytosol [GO:0005829] ATP binding [GO:0005524]; CTP synthase activity [GO:0003883]; identical protein binding [GO:0042802] 0.62913 0.40219 ITETEDPVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8141 0 0 0 Q9NRF9 DPOE3_HUMAN DNA polymerase epsilon subunit 3 (Arsenic-transactivated protein) (AsTP) (Chromatin accessibility complex 17 kDa protein) (CHRAC-17) (HuCHRAC17) (DNA polymerase II subunit 3) (DNA polymerase epsilon subunit p17) POLE3 CHRAC17 Homo sapiens (Human) chromatin remodeling [GO:0006338]; DNA damage response [GO:0006974]; DNA replication [GO:0006260]; DNA-templated DNA replication [GO:0006261]; heterochromatin formation [GO:0031507]; histone H3 acetylation [GO:0043966]; leading strand elongation [GO:0006272]; nucleosome assembly [GO:0006334]; regulation of DNA replication [GO:0006275] ATAC complex [GO:0140672]; CHRAC [GO:0008623]; epsilon DNA polymerase complex [GO:0008622]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721] chromatin DNA binding [GO:0031490]; DNA-directed DNA polymerase activity [GO:0003887]; protein heterodimerization activity [GO:0046982] 0.97021 -3.2906 EALEAYR 9.8828 0 0 0 0 0 0 0 0 0 0 0 0 9.41229 9.85381 0 11.5734 0 0 0 0 0 0 0 0 0 0 Q9NRG4 SMYD2_HUMAN N-lysine methyltransferase SMYD2 (EC 2.1.1.-) (HSKM-B) (Histone methyltransferase SMYD2) (EC 2.1.1.354) (Lysine N-methyltransferase 3C) (SET and MYND domain-containing protein 2) SMYD2 KMT3C Homo sapiens (Human) "heart development [GO:0007507]; histone lysine methylation [GO:0034968]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of signal transduction by p53 class mediator [GO:1901796]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] histone H3K36 methyltransferase activity [GO:0046975]; histone H3K4 trimethyltransferase activity [GO:0140999]; lysine N-methyltransferase activity [GO:0016278]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein-lysine N-methyltransferase activity [GO:0016279]; RNA polymerase II complex binding [GO:0000993] 0.92218 -1.1353 LGRLYMGLEHK 0 0 0 0 0 0 0 0 0 0 0 0 10.1586 0 0 10.7135 11.0934 0 0 0 0 0 0 0 0 0 0 Q9NRH1 YAE1_HUMAN Protein YAE1 homolog (Yae1 domain-containing protein 1) YAE1 C7orf36 YAE1D1 GK003 Homo sapiens (Human) protein maturation by [4Fe-4S] cluster transfer [GO:0106035] cytoplasm [GO:0005737]; nucleus [GO:0005634] 0.88421 -0.14531 IDEAKDERLCENNAEFNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.93402 0 0 0 0 0 0 0 0 0 0 Q9NRH2 SNRK_HUMAN SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1-related kinase) SNRK KIAA0096 SNFRK Homo sapiens (Human) intracellular signal transduction [GO:0035556]; myeloid cell differentiation [GO:0030099]; protein phosphorylation [GO:0006468] nucleus [GO:0005634] ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.84494 0.17517 LVQHPNIVR 0 0 0 11.0356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NRI5 DISC1_HUMAN Disrupted in schizophrenia 1 protein DISC1 KIAA0457 Homo sapiens (Human) "canonical Wnt signaling pathway [GO:0060070]; cell proliferation in forebrain [GO:0021846]; cilium assembly [GO:0060271]; microtubule cytoskeleton organization [GO:0000226]; mitochondrial calcium ion homeostasis [GO:0051560]; negative regulation of protein binding [GO:0032091]; neuron cellular homeostasis [GO:0070050]; neuron migration [GO:0001764]; non-motile cilium assembly [GO:1905515]; positive regulation of axon extension [GO:0045773]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of Wnt signaling pathway [GO:0030177]; protein localization to centrosome [GO:0071539]; pyramidal neuron migration to cerebral cortex [GO:0021852]; regulation of dendritic spine development [GO:0060998]; regulation of postsynapse organization [GO:0099175]; regulation of synapse maturation [GO:0090128]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to electrical stimulus [GO:0051602]; TOR signaling [GO:0031929]; ubiquitin-dependent protein catabolic process [GO:0006511]" cell body [GO:0044297]; central region of growth cone [GO:0090724]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary base [GO:0097546]; cytosol [GO:0005829]; dynein complex [GO:0030286]; endoplasmic reticulum [GO:0005783]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; intermediate filament cytoskeleton [GO:0045111]; kinesin complex [GO:0005871]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; synaptic vesicle [GO:0008021] identical protein binding [GO:0042802]; kinesin binding [GO:0019894]; molecular adaptor activity [GO:0060090]; protein-containing complex binding [GO:0044877] 0.85028 0.11643 EESYILSAELGEK 0 0 0 0 0 0 0 0 0 0 0 0 11.0381 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NRJ4 TULP4_HUMAN Tubby-related protein 4 (Tubby superfamily protein) (Tubby-like protein 4) TULP4 KIAA1397 TUBL4 TUSP Homo sapiens (Human) protein ubiquitination [GO:0016567] cytoplasm [GO:0005737]; cytosol [GO:0005829] 0.80921 0.23295 EATLKMAQLADSPR 0 14.2937 0 0 0 0 14.7745 0 9.01976 0 0 9.33345 0 0 0 0 0 12.3197 0 0 0 0 11.0904 0 0 0 0 Q9NRJ7 PCDBG_HUMAN Protocadherin beta-16 (PCDH-beta-16) (Protocadherin-3X) PCDHB16 KIAA1621 PCDH3X Homo sapiens (Human) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; synapse assembly [GO:0007416] membrane [GO:0016020]; plasma membrane [GO:0005886]; synapse [GO:0045202] calcium ion binding [GO:0005509] 0.96789 -2.7532 DLGLGLTEMSTRKAR 0 0 14.929 13.6061 0 13.4824 0 15.2489 0 0 0 0 0 0 0 0 0 0 10.2726 0 0 0 0 0 10.3429 0 10.0823 Q9NRL2 BAZ1A_HUMAN Bromodomain adjacent to zinc finger domain protein 1A (ATP-dependent chromatin-remodeling protein) (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (CHRAC subunit ACF1) (Williams syndrome transcription factor-related chromatin-remodeling factor 180) (WCRF180) (hWALp1) BAZ1A ACF1 WCRF180 HSPC317 Homo sapiens (Human) chromatin remodeling [GO:0006338]; DNA-templated DNA replication [GO:0006261]; nucleosome assembly [GO:0006334]; positive regulation of DNA replication [GO:0045740]; regulation of DNA replication [GO:0006275]; regulation of DNA-templated transcription [GO:0006355]; regulation of heterochromatin formation [GO:0031445]; regulation of transcription by RNA polymerase II [GO:0006357] ACF complex [GO:0016590]; CHRAC [GO:0008623]; nuclear chromosome [GO:0000228]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.96892 -3.872 DFIEDYVDILRQAK 0 0 10.3244 0 0 0 0 0 0 0 8.43221 0 0 0 0 0 0 0 9.45092 9.57879 9.00694 9.06862 9.3708 9.14883 0 0 11.7613 Q9NRM1 ENAM_HUMAN Enamelin ENAM Homo sapiens (Human) ameloblast differentiation [GO:0036305]; amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; positive regulation of enamel mineralization [GO:0070175] endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576] structural constituent of tooth enamel [GO:0030345] 0.9275 -1.1878 DDVSTLR 0 0 0 0 0 0 0 0 0 0 11.0038 0 0 0 9.58502 0 0 0 0 0 0 0 0 0 0 0 0 Q9NRM2 ZN277_HUMAN Zinc finger protein 277 (Nuclear receptor-interacting factor 4) ZNF277 NRIF4 ZNF277P Homo sapiens (Human) cellular response to hydrogen peroxide [GO:0070301]; regulation of cellular senescence [GO:2000772] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.92 -0.90474 KINPKNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.45154 0 Q9NRN5 OLFL3_HUMAN Olfactomedin-like protein 3 (HNOEL-iso) (hOLF44) OLFML3 PSEC0035 PSEC0173 PSEC0244 UNQ663/PRO1294 Homo sapiens (Human) signal transduction [GO:0007165] extracellular space [GO:0005615]; extracellular vesicle [GO:1903561] 0.93991 -1.3261 TEADTISGRVDRLER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.65388 0 0 0 0 0 0 0 0 Q9NRP4 SDHF3_HUMAN "Succinate dehydrogenase assembly factor 3, mitochondrial (SDH assembly factor 3) (SDHAF3)" SDHAF3 ACN9 DC11 Homo sapiens (Human) mitochondrial respiratory chain complex II assembly [GO:0034553]; regulation of gluconeogenesis [GO:0006111]; succinate metabolic process [GO:0006105] mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759] 0.87932 0.012542 SLGDQYVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.29255 0 Q9NRP7 STK36_HUMAN Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog) STK36 KIAA1278 Homo sapiens (Human) axoneme assembly [GO:0035082]; brain development [GO:0007420]; cilium assembly [GO:0060271]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of smoothened signaling pathway [GO:0045880]; post-embryonic development [GO:0009791]; protein phosphorylation [GO:0006468]; regulation of DNA-binding transcription factor activity [GO:0051090]; smoothened signaling pathway [GO:0007224] cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; transcription corepressor binding [GO:0001222] 0.93034 -1.2474 DMSSSEMWTVLWHR 0 0 0 0 10.132 0 0 0 0 0 0 0 0 0 0 0 0 10.7709 0 0 0 0 0 0 11.8778 0 0 Q9NRR2 TRYG1_HUMAN Tryptase gamma (EC 3.4.21.-) (Serine protease 31) (Transmembrane tryptase) [Cleaved into: Tryptase gamma light chain; Tryptase gamma heavy chain] TPSG1 PRSS31 TMT Homo sapiens (Human) proteolysis [GO:0006508] extracellular space [GO:0005615]; plasma membrane [GO:0005886] serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236] 0.90905 -0.74547 EVKVSVVDTETCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1311 0 0 0 Q9NRR3 C42S2_HUMAN CDC42 small effector protein 2 (Small effector of CDC42 protein 2) CDC42SE2 SPEC2 Homo sapiens (Human) phagocytosis [GO:0006909]; regulation of cell shape [GO:0008360]; regulation of Rho protein signal transduction [GO:0035023]; regulation of signal transduction [GO:0009966] cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886] signaling adaptor activity [GO:0035591]; small GTPase binding [GO:0031267] 0.84957 0.16239 GGYGGGMPANVQMQLVDTK 0 0 0 0 9.5345 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NRR4 RNC_HUMAN Ribonuclease 3 (EC 3.1.26.3) (Protein Drosha) (Ribonuclease III) (RNase III) (p241) DROSHA RN3 RNASE3L RNASEN Homo sapiens (Human) defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; miRNA metabolic process [GO:0010586]; mitochondrial translational elongation [GO:0070125]; positive regulation of gene expression [GO:0010628]; pre-miRNA processing [GO:0031054]; primary miRNA processing [GO:0031053]; regulation of inflammatory response [GO:0050727]; regulation of miRNA metabolic process [GO:2000628]; regulation of regulatory T cell differentiation [GO:0045589]; rRNA processing [GO:0006364] cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; microprocessor complex [GO:0070877]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; postsynaptic density [GO:0014069] DEAD/H-box RNA helicase binding [GO:0017151]; lipopolysaccharide binding [GO:0001530]; metal ion binding [GO:0046872]; primary miRNA binding [GO:0070878]; protein homodimerization activity [GO:0042803]; R-SMAD binding [GO:0070412]; ribonuclease III activity [GO:0004525]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; structural constituent of ribosome [GO:0003735] 0.95509 -1.6194 FVRFLPDGGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1404 0 0 Q9NRR6 INP5E_HUMAN "Phosphatidylinositol polyphosphate 5-phosphatase type IV (72 kDa inositol polyphosphate 5-phosphatase) (Inositol polyphosphate-5-phosphatase E) (Phosphatidylinositol 4,5-bisphosphate 5-phosphatase) (EC 3.1.3.36) (Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase) (EC 3.1.3.86)" INPP5E Homo sapiens (Human) negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of protein localization to cilium [GO:1903565]; negative regulation of translation [GO:0017148]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856] axoneme [GO:0005930]; cilium [GO:0005929]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ruffle [GO:0001726] "inositol-polyphosphate 5-phosphatase activity [GO:0004445]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity [GO:0034485]; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity [GO:0004439]" 0.95937 -1.7577 AAPIAPRPPARPR 0 0 0 0 0 9.49679 0 0 0 0 10.4433 10.5374 0 0 0 0 0 0 0 0 0 0 0 0 8.06878 8.84336 8.67708 Q9NRS4 TMPS4_HUMAN Transmembrane protease serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (CAPH2) (Membrane-type serine protease 2) (MT-SP2) [Cleaved into: Transmembrane protease serine 4 catalytic chain] TMPRSS4 TMPRSS3 UNQ776/PRO1570 Homo sapiens (Human) negative regulation of growth rate [GO:0045967]; positive regulation of viral entry into host cell [GO:0046598]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611] extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule [GO:0030141] scavenger receptor activity [GO:0005044]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236] 0.86227 0.095061 IIIIEFNPMYPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.90106 0 0 0 0 0 0 0 0 0 0 0 Q9NRS6 SNX15_HUMAN Sorting nexin-15 SNX15 Homo sapiens (Human) intracellular protein transport [GO:0006886] cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleolus [GO:0005730]; plasma membrane [GO:0005886] phosphatidylinositol binding [GO:0035091] 0.84303 0.17644 AGAYAAALQGYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.33031 0 0 0 0 0 0 0 0 0 Q9NRU3 CNNM1_HUMAN Metal transporter CNNM1 (Ancient conserved domain-containing protein 1) (Cyclin-M1) CNNM1 ACDP1 Homo sapiens (Human) magnesium ion homeostasis [GO:0010960]; monoatomic ion transport [GO:0006811] plasma membrane [GO:0005886] transmembrane transporter activity [GO:0022857] 0.96358 -2.4391 AWHHHGAAGGFLLR 0 0 0 0 0 0 0 9.57922 0 0 0 8.03974 8.83029 0 0 0 0 0 0 0 8.76567 0 0 0 0 0 0 Q9NRV9 HEBP1_HUMAN Heme-binding protein 1 (p22HBP) HEBP1 HBP Homo sapiens (Human) circadian rhythm [GO:0007623] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576] heme binding [GO:0020037] 0.89032 -0.49576 RNEIWLLK 0 0 10.8454 11.1583 0 11.4922 0 10.4778 0 0 11.257 0 9.52205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NRW1 RAB6B_HUMAN Ras-related protein Rab-6B (EC 3.6.5.2) RAB6B Homo sapiens (Human) "Golgi organization [GO:0007030]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; neuron projection development [GO:0031175]; protein localization to Golgi membrane [GO:1903292]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]" cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; presynapse [GO:0098793] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin V binding [GO:0031489] 0.92145 -1.0923 LQLWDTAGQER 9.27629 0 0 0 0 0 0 0 0 10.2009 9.64933 9.78813 9.70726 0 0 0 0 0 0 10.5187 8.26796 0 0 0 11.0077 0 0 Q9NRX2 RM17_HUMAN "Large ribosomal subunit protein bL17m (39S ribosomal protein L17, mitochondrial) (L17mt) (MRP-L17) (LYST-interacting protein 2)" MRPL17 LIP2 Homo sapiens (Human) mitochondrial translation [GO:0032543] mitochondrial inner membrane [GO:0005743]; mitochondrial large ribosomal subunit [GO:0005762]; mitochondrion [GO:0005739] protein domain specific binding [GO:0019904]; structural constituent of ribosome [GO:0003735] 0.94723 -1.3535 HERIEAPWARVDEMR 0 16.2125 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NRX5 SERC1_HUMAN Serine incorporator 1 (Tumor differentially expressed protein 1-like) (Tumor differentially expressed protein 2) SERINC1 KIAA1253 TDE1L TDE2 UNQ396/PRO732 Homo sapiens (Human) membrane biogenesis [GO:0044091]; phosphatidylserine metabolic process [GO:0006658]; phospholipid biosynthetic process [GO:0008654]; positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity [GO:1904219]; positive regulation of serine C-palmitoyltransferase activity [GO:1904222]; sphingolipid metabolic process [GO:0006665] endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886] protein-macromolecule adaptor activity [GO:0030674] 0.92388 -1.0229 LTLTSDESTLIEDGGAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.79828 0 0 0 Q9NRY4 RHG35_HUMAN Rho GTPase-activating protein 35 (Glucocorticoid receptor DNA-binding factor 1) (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A) ARHGAP35 GRF1 GRLF1 KIAA1722 P190A p190ARHOGAP Homo sapiens (Human) "axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; camera-type eye development [GO:0043010]; cell migration [GO:0016477]; cellular response to extracellular stimulus [GO:0031668]; central nervous system neuron axonogenesis [GO:0021955]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain development [GO:0030900]; mammary gland development [GO:0030879]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of vascular permeability [GO:0043116]; neural tube closure [GO:0001843]; neuron projection guidance [GO:0097485]; positive regulation of cilium assembly [GO:0045724]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron projection development [GO:0010976]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin polymerization or depolymerization [GO:0008064]; regulation of axonogenesis [GO:0050770]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; wound healing, spreading of cells [GO:0044319]" actin cytoskeleton [GO:0015629]; ciliary basal body [GO:0036064]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886] DNA binding [GO:0003677]; GTP binding [GO:0005525]; GTPase activating protein binding [GO:0032794]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; phospholipid binding [GO:0005543]; protein-containing complex binding [GO:0044877] 0.43243 0.65295 NLQVVETSAR 0 0 0 0 0 0 10.7668 0 0 0 0 11.5379 0 0 0 10.0404 0 0 0 0 0 0 0 0 0 0 0 Q9NRY5 F1142_HUMAN Protein FAM114A2 FAM114A2 C5orf3 Homo sapiens (Human) purine nucleotide binding [GO:0017076] 0.8973 -0.67247 EAKEKEEIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4402 0 0 0 0 0 Q9NRY7 PLS2_HUMAN Phospholipid scramblase 2 (PL scramblase 2) (Ca(2+)-dependent phospholipid scramblase 2) PLSCR2 Homo sapiens (Human) plasma membrane phospholipid scrambling [GO:0017121] endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; phospholipid scramblase activity [GO:0017128] 0.88497 -0.29616 ISKHWSGFLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1975 0 0 0 0 0 0 0 0 0 0 Q9NRZ5 PLCD_HUMAN 1-acyl-sn-glycerol-3-phosphate acyltransferase delta (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 4) (1-AGP acyltransferase 4) (1-AGPAT 4) (Lysophosphatidic acid acyltransferase delta) (LPAAT-delta) AGPAT4 UNQ499/PRO1016 Homo sapiens (Human) CDP-diacylglycerol biosynthetic process [GO:0016024]; phosphatidic acid biosynthetic process [GO:0006654]; phospholipid biosynthetic process [GO:0008654] endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741] 1-acylglycerol-3-phosphate O-acyltransferase activity [GO:0003841] 0.92031 -0.92273 GSAYGNSDSK 0 0 9.59595 0 0 0 0 0 0 0 0 0 0 0 9.95485 0 0 0 0 0 0 0 0 0 0 0 0 Q9NRZ7 PLCC_HUMAN 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 3) (1-AGP acyltransferase 3) (1-AGPAT 3) (Lysophosphatidic acid acyltransferase gamma) (LPAAT-gamma) AGPAT3 LPAAT3 UNQ759/PRO1490 Homo sapiens (Human) CDP-diacylglycerol biosynthetic process [GO:0016024]; phosphatidic acid biosynthetic process [GO:0006654]; phospholipid biosynthetic process [GO:0008654] endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886] 1-acylglycerol-3-phosphate O-acyltransferase activity [GO:0003841] 0.90639 -0.71686 GTVAAVYDVTLNFRGNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.2059 0 Q9NRZ9 HELLS_HUMAN Lymphoid-specific helicase (EC 3.6.4.-) (Proliferation-associated SNF2-like protein) (SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6) HELLS PASG SMARCA6 Nbla10143 Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to leukemia inhibitory factor [GO:1990830]; DNA methylation [GO:0006306]; DNA methylation-dependent heterochromatin formation [GO:0006346]; kidney development [GO:0001822]; lymphocyte proliferation [GO:0046651]; negative regulation of gene expression via CpG island methylation [GO:0044027]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; pericentric heterochromatin formation [GO:0031508]; urogenital system development [GO:0001655] "chromosome, centromeric region [GO:0000775]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]" ATP binding [GO:0005524]; ATP-dependent chromatin remodeler activity [GO:0140658]; chromatin binding [GO:0003682]; helicase activity [GO:0004386]; hydrolase activity [GO:0016787] 0.82579 0.21241 EDESYNISEVMSK 0 0 0 0 9.68285 10.7571 0 0 0 0 0 0 9.80195 0 10.2382 0 0 0 0 0 0 0 0 0 0 0 0 Q9NS15 LTBP3_HUMAN Latent-transforming growth factor beta-binding protein 3 (LTBP-3) LTBP3 Homo sapiens (Human) bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; bone remodeling [GO:0046849]; chondrocyte differentiation [GO:0002062]; lung saccule development [GO:0060430]; negative regulation of bone mineralization [GO:0030502]; negative regulation of chondrocyte differentiation [GO:0032331]; positive regulation of bone resorption [GO:0045780]; positive regulation of mesenchymal stem cell differentiation [GO:2000741]; positive regulation of mesenchymal stem cell proliferation [GO:1902462]; transforming growth factor beta activation [GO:0036363]; transforming growth factor beta receptor signaling pathway [GO:0007179] collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576] calcium ion binding [GO:0005509]; transforming growth factor beta binding [GO:0050431] 0.96415 -2.2709 RTCLKGQCR 0 0 10.1235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.72629 0 Q9NS28 RGS18_HUMAN Regulator of G-protein signaling 18 (RGS18) RGS18 RGS13 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; regulation of G protein-coupled receptor signaling pathway [GO:0008277] cytoplasm [GO:0005737]; plasma membrane [GO:0005886] GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924] 0.88364 -0.12635 TFFKLIHGSGKEETSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.89133 0 0 0 Q9NS37 ZHANG_HUMAN CREB/ATF bZIP transcription factor (Host cell factor-binding transcription factor Zhangfei) (HCF-binding transcription factor Zhangfei) CREBZF ZF Homo sapiens (Human) "ATF6-mediated unfolded protein response [GO:0036500]; integrated stress response signaling [GO:0140467]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression, epigenetic [GO:0045814]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription by RNA polymerase II [GO:0006357]; response to virus [GO:0009615]" chromatin [GO:0000785]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575] "DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]" 0.80848 0.22875 VQALQEESR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8003 0 Q9NS39 RED2_HUMAN Double-stranded RNA-specific editase B2 (EC 3.5.-.-) (RNA-dependent adenosine deaminase 3) (RNA-editing deaminase 2) (RNA-editing enzyme 2) (dsRNA adenosine deaminase B2) ADARB2 ADAR3 RED2 Homo sapiens (Human) adenosine to inosine editing [GO:0006382]; mRNA processing [GO:0006397]; RNA processing [GO:0006396] cytoplasm [GO:0005737]; nucleolus [GO:0005730] adenosine deaminase activity [GO:0004000]; double-stranded RNA adenosine deaminase activity [GO:0003726]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]; tRNA-specific adenosine deaminase activity [GO:0008251] 0.92468 -0.99014 GGAPGAK 9.48506 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.62487 0 0 0 Q9NS40 KCNH7_HUMAN Potassium voltage-gated channel subfamily H member 7 (Ether-a-go-go-related gene potassium channel 3) (ERG-3) (Eag-related protein 3) (Ether-a-go-go-related protein 3) (hERG-3) (Voltage-gated potassium channel subunit Kv11.3) KCNH7 ERG3 Homo sapiens (Human) circadian rhythm [GO:0007623]; membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; regulation of monoatomic ion transmembrane transport [GO:0034765] plasma membrane [GO:0005886] inward rectifier potassium channel activity [GO:0005242]; protein-containing complex binding [GO:0044877] 0.96701 -2.3215 AFRGASK 0 10.2775 0 0 0 0 0 0 8.90527 0 0 0 0 0 0 9.81068 0 0 0 0 0 0 0 0 0 0 9.13761 Q9NS56 TOPRS_HUMAN E3 ubiquitin-protein ligase Topors (EC 2.3.2.27) (RING-type E3 ubiquitin transferase Topors) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3) TOPORS LUN TP53BPL Homo sapiens (Human) DNA damage response [GO:0006974]; DNA-templated transcription [GO:0006351]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of apoptotic process [GO:0043066]; photoreceptor cell outer segment organization [GO:0035845]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein localization to nucleus [GO:0034504]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein sumoylation [GO:0016925]; regulation of cell population proliferation [GO:0042127]; retina layer formation [GO:0010842]; retinal cone cell development [GO:0046549]; retinal rod cell development [GO:0046548]; ubiquitin-dependent protein catabolic process [GO:0006511] centriole [GO:0005814]; ciliary basal body [GO:0036064]; gamma-tubulin complex [GO:0000930]; midbody [GO:0030496]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; photoreceptor connecting cilium [GO:0032391]; PML body [GO:0016605]; spindle pole [GO:0000922]; ubiquitin ligase complex [GO:0000151] antigen binding [GO:0003823]; DNA binding [GO:0003677]; DNA topoisomerase binding [GO:0044547]; metal ion binding [GO:0046872]; SUMO transferase activity [GO:0019789]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.96968 -6.0048 LDGNYKNESDTFSDSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.60949 0 0 0 0 Q9NS62 THSD1_HUMAN Thrombospondin type-1 domain-containing protein 1 (Transmembrane molecule with thrombospondin module) THSD1 TMTSP UNQ3010/PRO9769 Homo sapiens (Human) focal adhesion assembly [GO:0048041] cell periphery [GO:0071944]; cytosol [GO:0005829]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular region [GO:0005576]; focal adhesion [GO:0005925] extracellular matrix binding [GO:0050840] 0.96819 -3.6545 EAPRYPGKR 0 0 0 0 0 0 0 9.38937 0 0 0 0 0 0 8.44439 0 0 0 0 0 0 0 0 0 0 0 0 Q9NS73 MBIP1_HUMAN MAP3K12-binding inhibitory protein 1 (MAPK upstream kinase-binding inhibitory protein) (MUK-binding inhibitory protein) MBIP BM-015 Homo sapiens (Human) histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; positive regulation of gene expression [GO:0010628]; positive regulation of JNK cascade [GO:0046330]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of DNA-templated transcription [GO:0006355]; regulation of embryonic development [GO:0045995]; regulation of histone deacetylation [GO:0031063]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tubulin deacetylation [GO:0090043] ATAC complex [GO:0140672]; cytosol [GO:0005829]; mitotic spindle [GO:0072686]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] identical protein binding [GO:0042802]; protein kinase inhibitor activity [GO:0004860] 0.93973 -1.3251 RISAFIERK 0 10.3285 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NS84 CHST7_HUMAN Carbohydrate sulfotransferase 7 (EC 2.8.2.-) (EC 2.8.2.17) (Chondroitin 6-sulfotransferase 2) (C6ST-2) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 5) (GST-5) (N-acetylglucosamine 6-O-sulfotransferase 4) (GlcNAc6ST-4) (Gn6st-4) CHST7 Homo sapiens (Human) chondroitin sulfate biosynthetic process [GO:0030206]; N-acetylglucosamine metabolic process [GO:0006044]; polysaccharide metabolic process [GO:0005976]; sulfur compound metabolic process [GO:0006790] Golgi membrane [GO:0000139]; membrane [GO:0016020] chondroitin 6-sulfotransferase activity [GO:0008459]; N-acetylglucosamine 6-O-sulfotransferase activity [GO:0001517] 0.87012 0.051612 DAREAVHAWRER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.06134 0 9.45578 0 0 0 0 0 0 Q9NS85 CAH10_HUMAN Carbonic anhydrase-related protein 10 (Carbonic anhydrase-related protein X) (CA-RP X) (CARP X) (Cerebral protein 15) CA10 hucep-15 UNQ533/PRO1076 Homo sapiens (Human) brain development [GO:0007420] carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270] 0.8841 -0.14273 INTGGRKVSGTMYNTGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.2416 0 0 0 0 0 0 0 0 Q9NS87 KIF15_HUMAN Kinesin-like protein KIF15 (Kinesin-like protein 2) (hKLP2) (Kinesin-like protein 7) (Serologically defined breast cancer antigen NY-BR-62) KIF15 KLP2 KNSL7 Homo sapiens (Human) microtubule-based movement [GO:0007018]; mitotic cell cycle [GO:0000278]; regulation of mitotic spindle assembly [GO:1901673] centrosome [GO:0005813]; cytosol [GO:0005829]; kinesin complex [GO:0005871]; membrane [GO:0016020]; microtubule [GO:0005874]; plus-end kinesin complex [GO:0005873]; spindle [GO:0005819] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; cytoskeletal motor activity [GO:0003774]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777] 0.96234 -2.5081 AFSEISGMEK 12.353 0 0 0 0 0 0 0 0 0 0 0 11.0443 9.64847 0 10.3474 0 0 0 0 0 0 0 0 0 0 0 Q9NS93 TM7S3_HUMAN Transmembrane 7 superfamily member 3 (Seven span transmembrane protein) TM7SF3 Homo sapiens (Human) cellular response to unfolded protein [GO:0034620]; negative regulation of programmed cell death [GO:0043069]; positive regulation of insulin secretion [GO:0032024] extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] 0.86999 0.040299 GVDPPPCDAGTDQDSR 0 0 0 0 9.27929 0 0 0 0 10.2438 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NS98 SEM3G_HUMAN Semaphorin-3G (Semaphorin sem2) SEMA3G Homo sapiens (Human) negative chemotaxis [GO:0050919]; negative regulation of axon extension [GO:0030517]; negative regulation of axon extension involved in axon guidance [GO:0048843]; neural crest cell migration [GO:0001755]; positive regulation of cell migration [GO:0030335]; semaphorin-plexin signaling pathway [GO:0071526] extracellular exosome [GO:0070062] chemorepellent activity [GO:0045499]; semaphorin receptor binding [GO:0030215]; signaling receptor binding [GO:0005102] 0.95603 -1.5884 VWCRGTTECSGCFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2131 0 0 0 0 0 0 0 0 0 0 Q9NSB2 KRT84_HUMAN "Keratin, type II cuticular Hb4 (Keratin-84) (K84) (Type II hair keratin Hb4) (Type-II keratin Kb24)" KRT84 KRTHB4 Homo sapiens (Human) hair follicle development [GO:0001942]; keratinization [GO:0031424]; nail development [GO:0035878]; regulation of keratinocyte differentiation [GO:0045616] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; keratin filament [GO:0045095] structural constituent of cytoskeleton [GO:0005200]; structural constituent of skin epidermis [GO:0030280] 0.88411 -0.13769 AEIEHAKAQRAK 0 0 0 0 0 0 0 0 0 0 0 10.3407 0 0 0 0 0 0 11.0802 10.1482 10.8455 10.4322 10.3826 10.2341 11.4672 0 0 Q9NSB8 HOME2_HUMAN Homer protein homolog 2 (Homer-2) (Cupidin) HOMER2 Homo sapiens (Human) behavioral response to cocaine [GO:0048148]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of interleukin-2 production [GO:0032703]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; regulation of store-operated calcium entry [GO:2001256]; sensory perception of sound [GO:0007605] apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; intracellular organelle [GO:0043229]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; stereocilium tip [GO:0032426] actin binding [GO:0003779]; G protein-coupled glutamate receptor binding [GO:0035256]; synaptic receptor adaptor activity [GO:0030160] 0.95489 -1.5219 AHVFQIDPNTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0214 0 0 0 0 0 0 Q9NSC2 SALL1_HUMAN Sal-like protein 1 (Spalt-like transcription factor 1) (Zinc finger protein 794) (Zinc finger protein SALL1) (Zinc finger protein Spalt-1) (HSal1) (Sal-1) SALL1 SAL1 ZNF794 Homo sapiens (Human) adrenal gland development [GO:0030325]; branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic digestive tract development [GO:0048566]; embryonic digit morphogenesis [GO:0042733]; gonad development [GO:0008406]; heart development [GO:0007507]; inductive cell-cell signaling [GO:0031129]; kidney development [GO:0001822]; kidney epithelium development [GO:0072073]; limb development [GO:0060173]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory bulb mitral cell layer development [GO:0061034]; olfactory nerve development [GO:0021553]; pituitary gland development [GO:0021983]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of transcription by RNA polymerase II [GO:0006357]; ureteric bud development [GO:0001657]; ureteric bud invasion [GO:0072092]; ventricular septum development [GO:0003281] chromocenter [GO:0010369]; cytoplasm [GO:0005737]; heterochromatin [GO:0000792]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "beta-catenin binding [GO:0008013]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.56096 0.50711 FPFGGLLDSAQASETSK 0 0 0 10.1012 0 0 0 0 0 0 0 0 10.4941 10.4494 0 0 11.478 11.6496 0 0 0 0 0 0 0 0 0 Q9NSC5 HOME3_HUMAN Homer protein homolog 3 (Homer-3) HOMER3 Homo sapiens (Human) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of interleukin-2 production [GO:0032703]; protein targeting [GO:0006605]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of store-operated calcium entry [GO:2001256] basal part of cell [GO:0045178]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] G protein-coupled glutamate receptor binding [GO:0035256]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904] 0.89861 -0.64766 DQEIQTLKSQTGGPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.83988 0 0 0 0 0 0 0 0 0 0 9.65473 Q9NSC7 SIA7A_HUMAN "Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.3.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (ST6GalNAc-I) (ST6GalNAcI) (hST6GalNAc-I) (Sialyltransferase 7A) (SIAT7-A)" ST6GALNAC1 SIAT7A UNQ543/PRO848 Homo sapiens (Human) host-mediated regulation of intestinal microbiota composition [GO:0048874]; oligosaccharide biosynthetic process [GO:0009312]; protein glycosylation [GO:0006486] Golgi membrane [GO:0000139] "alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity [GO:0001665]; sialyltransferase activity [GO:0008373]; transferase activity [GO:0016740]" 0.91455 -0.76274 LEREVWKR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.71129 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NSD4 ZN275_HUMAN Zinc finger protein 275 ZNF275 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96765 -2.3463 ALENAAEKR 0 0 0 0 0 0 0 0 0 0 10.5736 0 0 0 0 0 0 0 0 0 8.69307 0 0 0 0 0 0 Q9NSD7 RL3R1_HUMAN Relaxin-3 receptor 1 (RLN3 receptor 1) (G protein-coupled receptor SALPR) (G-protein coupled receptor GPCR135) (Relaxin family peptide receptor 3) (Somatostatin- and angiotensin-like peptide receptor) RXFP3 GPCR135 RLN3R1 SALPR Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218]; positive regulation of cytokinesis [GO:0032467] plasma membrane [GO:0005886] G protein-coupled peptide receptor activity [GO:0008528]; G protein-coupled receptor activity [GO:0004930] 0.95445 -1.5022 DRQFWLGLYHSQK 0 10.8976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NSD9 SYFB_HUMAN Phenylalanine--tRNA ligase beta subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase beta subunit) (PheRS) FARSB FARSLB FRSB HSPC173 Homo sapiens (Human) phenylalanyl-tRNA aminoacylation [GO:0006432]; protein heterotetramerization [GO:0051290]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; phenylalanine-tRNA ligase complex [GO:0009328] ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; RNA binding [GO:0003723] 0.88781 -0.40076 ASEGPAFFPGR 0 0 0 0 0 0 0 9.68191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NSE4 SYIM_HUMAN "Isoleucine--tRNA ligase, mitochondrial (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IleRS)" IARS2 Homo sapiens (Human) isoleucyl-tRNA aminoacylation [GO:0006428]; mitochondrial translation [GO:0032543]; tRNA aminoacylation for protein translation [GO:0006418] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; isoleucine-tRNA ligase activity [GO:0004822]; tRNA binding [GO:0000049] 0.84977 0.11051 DTVLLPQTSFPMK 0 0 0 9.18448 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1249 Q9NSI6 BRWD1_HUMAN Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9) BRWD1 C21orf107 WDR9 Homo sapiens (Human) cytoskeleton organization [GO:0007010]; regulation of cell shape [GO:0008360]; regulation of transcription by RNA polymerase II [GO:0006357] cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.96933 -6.1597 IFTGSDDCLVKIWSTHNGR 0 0 0 0 9.72057 0 9.06824 0 0 0 9.35346 0 0 0 0 0 12.3432 0 0 9.52882 9.79022 11.2686 0 9.8775 0 0 11.2591 Q9NSJ1 Z355P_HUMAN Putative zinc finger protein 355P (Zinc finger protein ZnFP01) ZNF355P ZNF834 PRED65 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.77111 0.26806 IIHSGEKPYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.6157 0 0 10.2938 0 Q9NSK0 KLC4_HUMAN Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8) KLC4 KNSL8 Homo sapiens (Human) microtubule-based movement [GO:0007018] cytoplasm [GO:0005737]; kinesin complex [GO:0005871]; microtubule [GO:0005874] kinesin binding [GO:0019894] 0.82272 0.21586 HHEGGTPYAEYGGWYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.0771 0 11.5484 0 Q9NSP4 CENPM_HUMAN Centromere protein M (CENP-M) (Interphase centromere complex protein 39) (Proliferation-associated nuclear element protein 1) CENPM C22orf18 ICEN39 PANE1 Homo sapiens (Human) cytosol [GO:0005829]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654] 0.87082 0.034111 HVDASFFLGK 0 0 0 0 0 0 0 8.52239 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NST1 PLPL3_HUMAN 1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 (EC 2.3.1.51) (Acylglycerol transacylase) (Adiponutrin) (ADPN) (Calcium-independent phospholipase A2-epsilon) (iPLA2-epsilon) (EC 3.1.1.4) (Lysophosphatidic acid acyltransferase) (Patatin-like phospholipase domain-containing protein 3) (EC 3.1.1.3) PNPLA3 ADPN C22orf20 Homo sapiens (Human) "acylglycerol acyl-chain remodeling [GO:0036155]; cellular response to 3,3',5-triiodo-L-thyronine [GO:1905243]; cellular response to insulin stimulus [GO:0032869]; glycerophospholipid metabolic process [GO:0006650]; lipid droplet organization [GO:0034389]; lipid homeostasis [GO:0055088]; long-chain fatty acid metabolic process [GO:0001676]; phosphatidic acid biosynthetic process [GO:0006654]; response to sucrose [GO:0009744]; triglyceride acyl-chain remodeling [GO:0036153]; triglyceride biosynthetic process [GO:0019432]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]" cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; lipid droplet [GO:0005811]; membrane [GO:0016020] 1-acylglycerol-3-phosphate O-acyltransferase activity [GO:0003841]; acylglycerol O-acyltransferase activity [GO:0016411]; diolein transacylation activity [GO:0051265]; lipoprotein lipase activity [GO:0004465]; long-chain fatty acyl-CoA binding [GO:0036042]; lysophosphatidic acid acyltransferase activity [GO:0042171]; lysophosphatidic acid binding [GO:0035727]; mono-olein transacylation activity [GO:0051264]; phospholipase A2 activity [GO:0004623]; triglyceride lipase activity [GO:0004806] 0.81344 0.2216 VLMCLLPASR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3414 0 0 0 0 0 0 0 0 Q9NSV4 DIAP3_HUMAN Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (MDia2) DIAPH3 DIAP3 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament polymerization [GO:0030041]; cytoskeleton organization [GO:0007010] actin filament [GO:0005884]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] actin binding [GO:0003779]; cadherin binding [GO:0045296]; small GTPase binding [GO:0031267] 0.75967 0.29285 VCNHENQK 0 0 9.56904 0 0 0 0 0 9.28144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NSY0 NRBP2_HUMAN Nuclear receptor-binding protein 2 (Transformation-related gene 16 protein) (TRG-16) NRBP2 PP9320 TRG16 Homo sapiens (Human) negative regulation of macroautophagy [GO:0016242]; negative regulation of neuron apoptotic process [GO:0043524]; neuron differentiation [GO:0030182]; protein phosphorylation [GO:0006468] cytoplasm [GO:0005737] ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674] 0.91992 -0.90759 LAAFLESTFLKYRGTQA 0 0 0 9.34928 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NSY1 BMP2K_HUMAN BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1) BMP2K BIKE HRIHFB2017 Homo sapiens (Human) positive regulation of Notch signaling pathway [GO:0045747]; protein phosphorylation [GO:0006468]; regulation of bone mineralization [GO:0030500]; regulation of clathrin-dependent endocytosis [GO:2000369] cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleus [GO:0005634] AP-2 adaptor complex binding [GO:0035612]; ATP binding [GO:0005524]; phosphatase regulator activity [GO:0019208]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.88427 -0.13695 AQQPQQEK 0 0 0 0 0 0 0 0 0 0 9.72853 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NT22 EMIL3_HUMAN EMILIN-3 (EMILIN-5) (Elastin microfibril interface-located protein 3) (Elastin microfibril interfacer 3) (Elastin microfibril interface-located protein 5) (Elastin microfibril interfacer 5) EMILIN3 C20orf130 EMILIN5 Homo sapiens (Human) collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576] extracellular matrix constituent conferring elasticity [GO:0030023]; identical protein binding [GO:0042802] 0.93927 -1.3046 TVTDLAWR 0 0 0 0 0 0 0 0 9.73378 0 0 0 0 0 0 0 0 0 0 0 0 9.72935 0 0 10.9522 10.6765 11.5364 Q9NT62 ATG3_HUMAN Ubiquitin-like-conjugating enzyme ATG3 (EC 2.3.2.-) (Autophagy-related protein 3) (APG3-like) (hApg3) (Protein PC3-96) ATG3 APG3 APG3L Homo sapiens (Human) autophagosome assembly [GO:0000045]; autophagy of mitochondrion [GO:0000422]; autophagy of nucleus [GO:0044804]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; negative regulation of phagocytosis [GO:0050765]; protein targeting to membrane [GO:0006612]; protein ubiquitination [GO:0016567]; regulation of cilium assembly [GO:1902017] cytoplasm [GO:0005737]; cytosol [GO:0005829]; phagophore assembly site [GO:0000407] Atg12 transferase activity [GO:0019777]; Atg8 ligase activity [GO:0019776]; enzyme binding [GO:0019899]; ubiquitin-like protein transferase activity [GO:0019787] 0.93356 -1.2831 NVPCYKRCK 0 0 0 0 0 0 0 0 0 0 0 0 11.1537 0 0 0 0 0 0 0 12.3016 0 0 0 0 0 0 Q9NT68 TEN2_HUMAN "Teneurin-2 (Ten-2) (Protein Odd Oz/ten-m homolog 2) (Tenascin-M2) (Ten-m2) (Teneurin transmembrane protein 2) [Cleaved into: Ten-2, soluble form; Ten-2 intracellular domain (Ten-2 ICD)]" TENM2 KIAA1127 ODZ2 TNM2 Homo sapiens (Human) axon guidance [GO:0007411]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell-cell adhesion [GO:0098609]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron development [GO:0048666]; positive regulation of filopodium assembly [GO:0051491]; retrograde trans-synaptic signaling by trans-synaptic protein complex [GO:0098942]; signal transduction [GO:0007165] cell junction [GO:0030054]; cell-cell junction [GO:0005911]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202] calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102] 0.96885 -10.418 ALGTAWAKEQQK 12.5286 0 0 0 0 11.5499 10.3318 0 0 10.6923 11.5321 0 0 0 10.8067 0 0 11.5072 0 0 8.9053 0 0 0 0 0 0 Q9NTG1 PKDRE_HUMAN Polycystin family receptor for egg jelly (PKD and REJ homolog) (Polycystic kidney disease and receptor for egg jelly-related protein) PKDREJ Homo sapiens (Human) acrosome reaction [GO:0007340]; detection of mechanical stimulus [GO:0050982] membrane [GO:0016020] calcium channel activity [GO:0005262]; calcium ion binding [GO:0005509] 0.95472 -1.5361 ILGLPLMRQVR 0 0 0 0 0 8.88926 0 0 0 8.6732 0 0 0 0 0 0 0 0 0 0 10.1426 0 0 0 0 0 0 Q9NTG7 SIR3_HUMAN "NAD-dependent protein deacetylase sirtuin-3, mitochondrial (hSIRT3) (EC 2.3.1.286) (Regulatory protein SIR2 homolog 3) (SIR2-like protein 3)" SIRT3 SIR2L3 Homo sapiens (Human) aerobic respiration [GO:0009060]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of catalase activity [GO:1902553]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of superoxide dismutase activity [GO:1901671]; protein deacetylation [GO:0006476] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent protein deacetylase activity [GO:0034979]; sequence-specific DNA binding [GO:0043565]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270] 0.95113 -1.4339 AAAPSFFFSSIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1126 0 0 0 0 9.33441 0 0 0 0 0 Q9NTI2 AT8A2_HUMAN Phospholipid-transporting ATPase IB (EC 7.6.2.1) (ATPase class I type 8A member 2) (ML-1) (P4-ATPase flippase complex alpha subunit ATP8A2) ATP8A2 ATPIB Homo sapiens (Human) aging [GO:0007568]; aminophospholipid translocation [GO:0140331]; axonogenesis [GO:0007409]; detection of light stimulus involved in visual perception [GO:0050908]; eating behavior [GO:0042755]; inner ear morphogenesis [GO:0042472]; involuntary skeletal muscle contraction [GO:0003011]; negative regulation of cell population proliferation [GO:0008285]; neurofilament cytoskeleton organization [GO:0060052]; neuromuscular process controlling posture [GO:0050884]; neuron development [GO:0048666]; phospholipid translocation [GO:0045332]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phospholipid translocation [GO:0061092]; response to auditory stimulus [GO:0010996]; retina layer formation [GO:0010842]; skin development [GO:0043588] cell projection [GO:0042995]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; phospholipid-translocating ATPase complex [GO:1990531]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled intramembrane lipid transporter activity [GO:0140326]; magnesium ion binding [GO:0000287]; phosphatidylethanolamine flippase activity [GO:0090555]; phosphatidylserine flippase activity [GO:0140346]; phosphatidylserine floppase activity [GO:0090556] 0.96942 -3.393 AVLRDSNGK 0 9.8603 0 0 0 0 0 0 0 9.82512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5562 0 0 Q9NTI5 PDS5B_HUMAN Sister chromatid cohesion protein PDS5 homolog B (Androgen-induced proliferation inhibitor) (Androgen-induced prostate proliferative shutoff-associated protein AS3) PDS5B APRIN AS3 KIAA0979 Homo sapiens (Human) cell division [GO:0051301]; cell population proliferation [GO:0008283]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of cell population proliferation [GO:0008285]; regulation of cell population proliferation [GO:0042127] "chromatin [GO:0000785]; chromosome [GO:0005694]; chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]" DNA binding [GO:0003677] 0.95973 -1.728 ISKPDMSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.75962 0 0 12.1181 0 0 0 9.29806 0 0 Q9NTI7 INKA2_HUMAN PAK4-inhibitor INKA2 (Induced in neural crest by AP2-alpha protein-related homolog) (HInca-r) (Inka box actin regulator 2) INKA2 C1orf183 FAM212B Homo sapiens (Human) intracellular membrane-bounded organelle [GO:0043231]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] protein kinase binding [GO:0019901]; protein serine/threonine kinase inhibitor activity [GO:0030291] 0.65107 0.39598 GETGGAR 0 0 0 0 0 0 0 0 0 9.48055 9.58425 9.78635 0 0 0 0 0 8.47569 0 0 0 0 0 0 9.36418 0 9.36606 Q9NTJ3 SMC4_HUMAN Structural maintenance of chromosomes protein 4 (SMC protein 4) (SMC-4) (Chromosome-associated polypeptide C) (hCAP-C) (XCAP-C homolog) SMC4 CAPC SMC4L1 Homo sapiens (Human) cell division [GO:0051301]; kinetochore organization [GO:0051383]; meiotic chromosome condensation [GO:0010032]; meiotic chromosome segregation [GO:0045132]; mitotic chromosome condensation [GO:0007076]; mitotic sister chromatid segregation [GO:0000070]; positive regulation of chromosome condensation [GO:1905821]; positive regulation of chromosome segregation [GO:0051984]; positive regulation of chromosome separation [GO:1905820] "chromosome, centromeric region [GO:0000775]; condensed nuclear chromosome [GO:0000794]; condensin complex [GO:0000796]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]" ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; chromatin binding [GO:0003682]; single-stranded DNA binding [GO:0003697] 0.96869 -8.5589 AMQIQEQK 0 9.36934 0 0 0 0 10.0455 0 0 0 0 0 0 0 10.5383 0 0 0 9.54243 0 11.3514 11.1828 9.79671 11.2011 8.7076 0 10.0848 Q9NTJ4 MA2C1_HUMAN Alpha-mannosidase 2C1 (EC 3.2.1.24) (Alpha mannosidase 6A8B) (Alpha-D-mannoside mannohydrolase) (Mannosidase alpha class 2C member 1) MAN2C1 MANA MANA1 Homo sapiens (Human) mannose metabolic process [GO:0006013]; oligosaccharide catabolic process [GO:0009313] cytosol [GO:0005829]; nucleoplasm [GO:0005654] alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872] 0.6314 0.40594 SWVTALQLMER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.55463 0 0 0 0 10.4031 Q9NTJ5 SAC1_HUMAN Phosphatidylinositol-3-phosphatase SAC1 (EC 3.1.3.64) (Phosphatidylinositol-4-phosphate phosphatase) (Suppressor of actin mutations 1-like protein) SACM1L KIAA0851 SAC1 Homo sapiens (Human) phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-plasma membrane contact site [GO:0140268]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139] phosphatase activity [GO:0016791]; phosphatidylinositol phosphate 4-phosphatase activity [GO:0034596]; phosphatidylinositol-3-phosphate phosphatase activity [GO:0004438]; phosphatidylinositol-4-phosphate phosphatase activity [GO:0043812] 0.92487 -1.0008 LEEQDEFEK 0 0 0 0 0 0 0 0 0 0 0 0 8.33856 0 11.7446 0 0 9.26231 0 0 0 0 0 0 0 0 0 Q9NTK1 DEPP1_HUMAN Protein DEPP1 (Decidual protein induced by progesterone) (Fasting-induced gene protein) (FIG) DEPP1 C10orf10 DEPP FIG Homo sapiens (Human) autophagy [GO:0006914]; regulation of autophagy [GO:0010506] cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; peroxisome [GO:0005777] 0.56394 0.48909 LAQPTSVLDK 0 0 0 8.80632 0 8.72291 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0775 0 0 0 0 0 0 Q9NTK5 OLA1_HUMAN Obg-like ATPase 1 (DNA damage-regulated overexpressed in cancer 45) (DOC45) (GTP-binding protein 9) OLA1 GTPBP9 PRO2455 PTD004 Homo sapiens (Human) ATP metabolic process [GO:0046034] centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nucleolus [GO:0005730]; platelet alpha granule lumen [GO:0031093] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; cadherin binding [GO:0045296]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; ribosomal large subunit binding [GO:0043023] 0 3.809 AFEDDDITHVEGSVDPIR 10.6811 10.4256 10.4543 0 9.35694 0 10.95 17.1889 10.8566 11.4241 11.4555 11.5298 0 0 9.95126 0 0 11.0893 0 9.83679 0 0 10.1076 0 0 0 0 Q9NTM9 CUTC_HUMAN Copper homeostasis protein cutC homolog CUTC CGI-32 Homo sapiens (Human) copper ion homeostasis [GO:0055070]; copper ion transport [GO:0006825]; protein tetramerization [GO:0051262] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] copper ion binding [GO:0005507] 0.37294 0.72708 ILEGSGATEFHCSARSTR 0 0 0 0 0 0 0 0 0 9.89691 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NTW7 ZF64B_HUMAN Zinc finger protein 64 (Zfp-64) (Zinc finger protein 338) ZFP64 ZNF338 Homo sapiens (Human) mesenchymal cell differentiation [GO:0048762]; regulation of gene expression [GO:0010468] cytoplasm [GO:0005737]; megasporocyte nucleus [GO:0043076]; nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.96943 -3.468 CEFCDVRCTMK 9.75097 9.84332 9.97742 0 0 0 0 9.47778 0 12.203 12.0041 12.2379 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NTX7 RN146_HUMAN E3 ubiquitin-protein ligase RNF146 (EC 2.3.2.27) (Dactylidin) (Iduna) (RING finger protein 146) (RING-type E3 ubiquitin transferase RNF146) RNF146 Homo sapiens (Human) positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] poly-ADP-D-ribose binding [GO:0072572]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.92681 -1.2202 HVFCYLCVK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7084 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NTX9 F217B_HUMAN Protein FAM217B FAM217B C20orf177 Homo sapiens (Human) cytosol [GO:0005829]; nucleoplasm [GO:0005654] 0.96153 -2.0642 NPLGSRCQGASGNKLFLDFQSMK 0 0 0 0 0 0 0 12.4489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NTZ6 RBM12_HUMAN RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN) RBM12 KIAA0765 HRIHFB2091 Homo sapiens (Human) regulation of RNA splicing [GO:0043484] nucleoplasm [GO:0005654]; ribonucleoprotein complex [GO:1990904] RNA binding [GO:0003723] 0.95468 -1.5084 ATGEGFVEFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5252 0 Q9NU02 ANKE1_HUMAN Ankyrin repeat and EF-hand domain-containing protein 1 (Ankyrin repeat domain-containing protein 5) ANKEF1 ANKRD5 Homo sapiens (Human) calcium ion binding [GO:0005509] 0.91422 -0.83131 AFESGIPVDMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5652 0 9.38896 0 0 0 0 0 0 Q9NU19 TB22B_HUMAN TBC1 domain family member 22B TBC1D22B C6orf197 Homo sapiens (Human) activation of GTPase activity [GO:0090630] 14-3-3 protein binding [GO:0071889]; GTPase activator activity [GO:0005096] 0.81232 0.22413 ASSFHEFAR 0 0 0 0 0 0 0 0 0 0 9.66816 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NU22 MDN1_HUMAN Midasin (Dynein-related AAA-ATPase MDN1) (MIDAS-containing protein) MDN1 KIAA0301 Homo sapiens (Human) ribosomal large subunit assembly [GO:0000027]; ribosomal large subunit export from nucleus [GO:0000055] "cytosol [GO:0005829]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; preribosome, large subunit precursor [GO:0030687]" ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887] 0.96925 -3.4648 DLLNWCNR 13.353 12.9444 13.2566 10.6793 11.073 10.915 12.5065 12.7649 12.3763 12.7223 12.5646 12.8896 0 12.3188 11.6814 0 0 0 0 0 0 0 10.6645 0 0 0 0 Q9NU63 ZFP57_HUMAN Zinc finger protein 57 homolog (Zfp-57) (Zinc finger protein 698) ZFP57 C6orf40 ZNF698 Homo sapiens (Human) DNA methylation involved in embryo development [GO:0043045]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of gene expression by genomic imprinting [GO:0006349] nucleus [GO:0005634] "chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.87603 -0.0085876 LEQEEEQWR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.63396 0 0 0 0 0 0 0 0 Q9NUA8 ZBT40_HUMAN Zinc finger and BTB domain-containing protein 40 ZBTB40 KIAA0478 Homo sapiens (Human) bone mineralization [GO:0030282]; DNA damage response [GO:0006974]; regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]" 0.95991 -1.9263 CFEGEGGHSAFQR 0 0 0 0 0 0 0 0 0 0 9.28545 0 0 0 0 0 10.1081 0 0 0 0 0 0 0 0 0 0 Q9NUC0 SRTD4_HUMAN SERTA domain-containing protein 4 SERTAD4 Homo sapiens (Human) nucleus [GO:0005634] 0.84104 0.18351 TLVLSMNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.78599 0 0 0 0 0 0 0 0 0 0 0 0 Q9NUD5 ZCHC3_HUMAN Zinc finger CCHC domain-containing protein 3 ZCCHC3 C20orf99 Homo sapiens (Human) activation of innate immune response [GO:0002218]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; detection of virus [GO:0009597]; innate immune response [GO:0045087]; positive regulation of RIG-I signaling pathway [GO:1900246]; positive regulation of type I interferon production [GO:0032481] cytoplasm [GO:0005737] double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270] 0.91539 -0.80646 CFRCGEEGHLSPYCR 0 0 0 0 0 0 9.97685 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NUD7 CT096_HUMAN Uncharacterized protein C20orf96 C20orf96 Homo sapiens (Human) 0.9557 -1.6365 MWESQDFLKCMQRFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.44595 9.53842 0 0 0 0 0 0 0 0 Q9NUG4 CCM2L_HUMAN Cerebral cavernous malformations 2 protein-like (CCM2-like) CCM2L C20orf160 Homo sapiens (Human) heart morphogenesis [GO:0003007] 0.93297 -1.2589 AGRRAACR 0 8.72714 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NUG6 PDRG1_HUMAN p53 and DNA damage-regulated protein 1 PDRG1 C20orf126 PDRG Homo sapiens (Human) protein folding [GO:0006457]; protein stabilization [GO:0050821] cytoplasm [GO:0005737]; prefoldin complex [GO:0016272]; protein folding chaperone complex [GO:0101031]; RPAP3/R2TP/prefoldin-like complex [GO:1990062] unfolded protein binding [GO:0051082] 0.84447 0.13719 YLVEVEELAEEVLADK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5259 0 0 0 10.4921 0 10.1467 0 0 0 0 12.4023 0 Q9NUJ1 ABHDA_HUMAN "Palmitoyl-protein thioesterase ABHD10, mitochondrial (EC 3.1.2.22) (Acyl-protein thioesterase ABHD10) (Alpha/beta hydrolase domain-containing protein 10) (Abhydrolase domain-containing protein 10) (Mycophenolic acid acyl-glucuronide esterase, mitochondrial) (EC 3.1.1.93)" ABHD10 Homo sapiens (Human) cellular glucuronidation [GO:0052695]; glucuronoside catabolic process [GO:0019391]; protein depalmitoylation [GO:0002084] cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] "hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; mycophenolic acid acyl-glucuronide esterase activity [GO:0102390]; palmitoyl-(protein) hydrolase activity [GO:0008474]" 0.92693 -1.2199 EVEMKGVWSMPSK 0 0 0 10.237 0 9.83779 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NUJ7 PLCX1_HUMAN PI-PLC X domain-containing protein 1 PLCXD1 Homo sapiens (Human) lipid metabolic process [GO:0006629] cytoplasm [GO:0005737] phosphoric diester hydrolase activity [GO:0008081] 0.8493 0.16432 GQQVIVSYEDESSLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.71462 0 0 0 0 0 0 0 0 0 0 0 Q9NUK0 MBNL3_HUMAN Muscleblind-like protein 3 (Cys3His CCG1-required protein) (Muscleblind-like X-linked protein) (Protein HCHCR) MBNL3 CHCR MBLX39 MBXL Homo sapiens (Human) mRNA processing [GO:0006397]; negative regulation of myoblast differentiation [GO:0045662]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA binding [GO:0003723] 0.88458 -0.33377 EFQRGTCSR 0 0 0 0 0 0 0 0 0 9.3501 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NUL3 STAU2_HUMAN Double-stranded RNA-binding protein Staufen homolog 2 STAU2 Homo sapiens (Human) anterograde dendritic transport of messenger ribonucleoprotein complex [GO:0098964]; cellular response to oxidative stress [GO:0034599]; eye morphogenesis [GO:0048592]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of long-term synaptic depression [GO:1900454]; positive regulation of synapse assembly [GO:0051965]; protein localization to synapse [GO:0035418]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of filopodium assembly [GO:0051489]; regulation of gene expression [GO:0010468] axon [GO:0030424]; cytoplasmic stress granule [GO:0010494]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; endoplasmic reticulum [GO:0005783]; membrane [GO:0016020]; messenger ribonucleoprotein complex [GO:1990124]; microtubule [GO:0005874]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730] double-stranded RNA binding [GO:0003725]; Hsp70 protein binding [GO:0030544]; kinesin binding [GO:0019894]; mitogen-activated protein kinase binding [GO:0051019]; ribosome binding [GO:0043022]; RNA binding [GO:0003723] 0.87077 0.033489 GWSGPKPGFPEPTNNTPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.2276 0 0 0 0 0 0 0 0 0 Q9NUL7 DDX28_HUMAN Probable ATP-dependent RNA helicase DDX28 (EC 3.6.4.13) (Mitochondrial DEAD box protein 28) DDX28 MDDX28 Homo sapiens (Human) mitochondrial large ribosomal subunit assembly [GO:1902775] cytosol [GO:0005829]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; ribonucleoprotein granule [GO:0035770] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; rRNA binding [GO:0019843] 0.95116 -1.3838 GLVLVPSR 10.4815 0 0 0 0 0 0 0 0 0 0 0 0 9.78072 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NUN5 LMBD1_HUMAN Lysosomal cobalamin transport escort protein LMBD1 (LMBD1) (HDAg-L-interacting protein NESI) (LMBR1 domain-containing protein 1) (Nuclear export signal-interacting protein) LMBRD1 C6orf209 NESI BM-021 CD001 MSTP044 Homo sapiens (Human) clathrin-dependent endocytosis [GO:0072583]; gastrulation [GO:0007369]; insulin receptor internalization [GO:0038016]; protein localization to lysosome [GO:0061462] clathrin-coated endocytic vesicle [GO:0045334]; clathrin-coated vesicle [GO:0030136]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886] AP-2 adaptor complex binding [GO:0035612]; clathrin heavy chain binding [GO:0032050]; cobalamin binding [GO:0031419]; insulin receptor binding [GO:0005158]; protein transporter activity [GO:0140318] 0.84793 0.15414 TYLFLHK 0 9.96737 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NUP7 TRM13_HUMAN tRNA:m(4)X modification enzyme TRM13 homolog (EC 2.1.1.225) (Coiled-coil domain-containing protein 76) TRMT13 CCDC76 Homo sapiens (Human) tRNA methylation [GO:0030488] metal ion binding [GO:0046872]; tRNA 2'-O-methyltransferase activity [GO:0106050]; tRNA methyltransferase activity [GO:0008175] 0.91754 -0.8591 EGNEKNVPEK 9.51475 0 0 0 0 0 0 0 0 0 10.165 0 0 0 0 0 0 0 0 0 0 9.1873 0 0 0 0 0 Q9NUQ2 PLCE_HUMAN 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 5) (1-AGP acyltransferase 5) (1-AGPAT 5) (Lysophosphatidic acid acyltransferase epsilon) (LPAAT-epsilon) AGPAT5 Homo sapiens (Human) acylglycerol metabolic process [GO:0006639]; CDP-diacylglycerol biosynthetic process [GO:0016024]; hematopoietic progenitor cell differentiation [GO:0002244]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phospholipid biosynthetic process [GO:0008654] endomembrane system [GO:0012505]; endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730] 1-acylglycerol-3-phosphate O-acyltransferase activity [GO:0003841]; acyltransferase activity [GO:0016746] 0.27548 0.83808 LLSAFLPAR 0 9.7225 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4134 11.3881 0 0 0 0 0 0 0 Q9NUQ3 TXLNG_HUMAN Gamma-taxilin (Environmental lipopolysaccharide-responding gene protein) (Factor inhibiting ATF4-mediated transcription) (FIAT) (Lipopolysaccharide-specific response protein 5) TXLNG CXorf15 ELRG LSR5 Homo sapiens (Human) cell cycle [GO:0007049]; regulation of bone mineralization [GO:0030500]; regulation of cell cycle [GO:0051726]; regulation of cell cycle process [GO:0010564] cytosol [GO:0005829]; nuclear membrane [GO:0031965] DNA-binding transcription factor binding [GO:0140297]; syntaxin binding [GO:0019905] 0.96334 -2.1302 EENMQQAREEEERR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2697 0 0 0 0 0 0 Q9NUQ7 UFSP2_HUMAN Ufm1-specific protease 2 (UfSP2) (EC 3.4.22.-) UFSP2 C4orf20 Homo sapiens (Human) proteolysis [GO:0006508]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146] cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634] deUFMylase activity [GO:0071567] 0.91486 -0.81293 CILKYMK 9.14392 0 9.44855 0 0 9.23213 0 0 0 0 10.325 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NUQ9 CYRIB_HUMAN CYFIP-related Rac1 interactor B (L1) CYRIB CYRI FAM49B BM-009 Homo sapiens (Human) cellular response to molecule of bacterial origin [GO:0071219]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of small GTPase mediated signal transduction [GO:0051058]; positive regulation of memory T cell activation [GO:2000568]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of type II interferon production [GO:0032729]; regulation of cell migration [GO:0030334]; regulation of chemotaxis [GO:0050920]; regulation of establishment of cell polarity [GO:2000114]; regulation of mitochondrial fission [GO:0090140] cilium [GO:0005929]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; mitochondrion [GO:0005739]; platelet alpha granule lumen [GO:0031093] "MHC class Ib protein binding, via antigen binding groove [GO:0023030]; small GTPase binding [GO:0031267]" 0.87173 0.06131 DAEGILEDLQSYRGAGHEIREAIQHPADEK 0 0 0 0 0 0 0 0 10.726 0 0 0 0 0 9.20958 0 0 0 0 0 0 0 0 0 11.3035 0 0 Q9NUT2 MITOS_HUMAN "Mitochondrial potassium channel ATP-binding subunit (ATP-binding cassette sub-family B member 8, mitochondrial) (ABCB8) (Mitochondrial ATP-binding cassette 1) (M-ABC1) (Mitochondrial sulfonylurea-receptor) (MITOSUR)" ABCB8 MABC1 MITOSUR Homo sapiens (Human) cell volume homeostasis [GO:0006884]; mitochondrial potassium ion transmembrane transport [GO:0140141]; potassium ion transmembrane transport [GO:0071805]; transmembrane transport [GO:0055085] ATP-binding cassette (ABC) transporter complex [GO:0043190]; mitochondrial ATP-gated potassium channel complex [GO:0062157]; mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] ABC-type transporter activity [GO:0140359]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626] 0.9631 -2.1223 GAHCIVVMADGR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.30248 0 0 0 0 0 0 0 0 0 0 0 9.09521 10.2764 Q9NUU6 OTULL_HUMAN Inactive ubiquitin thioesterase OTULINL OTULINL FAM105A Homo sapiens (Human) cytoplasm [GO:0005737]; cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; nuclear envelope [GO:0005635] 0.91608 -0.77165 FIMLYQVTEVYEQMK 0 0 0 0 0 0 0 0 0 0 9.11481 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NUU7 DD19A_HUMAN ATP-dependent RNA helicase DDX19A (EC 3.6.4.13) (DDX19-like protein) (DEAD box protein 19A) DDX19A DDX19L Homo sapiens (Human) poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of apoptotic process [GO:0043065]; response to zinc ion [GO:0010043] cytoplasmic stress granule [GO:0010494]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.95814 -1.6731 GLAVNMVDSK 0 0 0 0 13.341 13.4824 15.2989 0 0 10.378 0 10.002 0 0 9.2446 0 0 0 0 0 0 0 0 0 11.4789 0 0 Q9NUV7 SPTC3_HUMAN Serine palmitoyltransferase 3 (EC 2.3.1.50) (Long chain base biosynthesis protein 2b) (LCB2b) (Long chain base biosynthesis protein 3) (LCB 3) (Serine-palmitoyl-CoA transferase 3) (SPT 3) SPTLC3 C20orf38 SPTLC2L Homo sapiens (Human) ceramide biosynthetic process [GO:0046513]; sphingoid biosynthetic process [GO:0046520]; sphingolipid biosynthetic process [GO:0030148]; sphingosine biosynthetic process [GO:0046512] endoplasmic reticulum membrane [GO:0005789]; serine C-palmitoyltransferase complex [GO:0017059] pyridoxal phosphate binding [GO:0030170]; serine C-palmitoyltransferase activity [GO:0004758] 0.96955 -4.5992 ARFCVSAAHTR 0 0 0 0 0 0 0 0 0 0 0 9.08494 0 0 0 10.3336 0 0 0 0 0 0 10.0246 0 0 0 0 Q9NUV9 GIMA4_HUMAN GTPase IMAP family member 4 (Immunity-associated nucleotide 1 protein) (IAN-1) (hIAN1) (Immunity-associated protein 4) GIMAP4 IAN1 IMAP4 MSTP062 Homo sapiens (Human) cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231] GTP binding [GO:0005525] 0.88176 -0.31031 AEEEIQK 0 0 0 0 0 0 0 0 0 0 10.4781 8.74167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NUW8 TYDP1_HUMAN Tyrosyl-DNA phosphodiesterase 1 (Tyr-DNA phosphodiesterase 1) (EC 3.1.4.-) TDP1 Homo sapiens (Human) DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; single strand break repair [GO:0000012] cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] 3'-tyrosyl-DNA phosphodiesterase activity [GO:0017005]; double-stranded DNA binding [GO:0003690]; exonuclease activity [GO:0004527]; single-stranded DNA binding [GO:0003697] 0.95023 -1.382 WLCSEFKESMLTLGKESK 0 0 0 10.832 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NUX5 POTE1_HUMAN Protection of telomeres protein 1 (hPot1) (POT1-like telomere end-binding protein) POT1 Homo sapiens (Human) DNA duplex unwinding [GO:0032508]; establishment of protein localization to telomere [GO:0070200]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; positive regulation of DNA helicase activity [GO:1905776]; positive regulation of DNA strand elongation [GO:0060383]; positive regulation of helicase activity [GO:0051096]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere maintenance [GO:0032206]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of DNA helicase activity [GO:1905774]; regulation of double-strand break repair via nonhomologous end joining [GO:2001032]; regulation of telomere maintenance via telomerase [GO:0032210]; telomere assembly [GO:0032202]; telomere capping [GO:0016233]; telomere maintenance via telomerase [GO:0007004]; telomeric D-loop disassembly [GO:0061820] "chromosome, telomeric region [GO:0000781]; nuclear telomere cap complex [GO:0000783]; nucleoplasm [GO:0005654]; shelterin complex [GO:0070187]" 8-hydroxy-2'-deoxyguanosine DNA binding [GO:1905773]; DEAD/H-box RNA helicase binding [GO:0017151]; G-rich single-stranded DNA binding [GO:1990955]; G-rich strand telomeric DNA binding [GO:0098505]; single-stranded telomeric DNA binding [GO:0043047]; telomerase inhibitor activity [GO:0010521]; telomeric D-loop binding [GO:0061821]; telomeric DNA binding [GO:0042162] 0.96194 -2.0675 LRSYKPRR 0 0 0 0 0 0 0 0 11.141 0 0 0 0 0 0 0 0 0 0 0 10.6662 0 0 0 0 0 0 Q9NUZ1 ACOXL_HUMAN Acyl-coenzyme A oxidase-like protein (Acyl-CoA oxidase-like protein) (EC 1.3.3.-) ACOXL Homo sapiens (Human) fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088] peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777] acyl-CoA oxidase activity [GO:0003997]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660] 0.96912 -4.4647 GHGSNAR 0 0 0 0 0 0 0 0 0 9.99181 9.20955 0 0 0 0 0 0 0 0 9.9497 0 0 0 0 0 0 0 Q9NV06 DCA13_HUMAN DDB1- and CUL4-associated factor 13 (WD repeat and SOF domain-containing protein 1) DCAF13 WDSOF1 HSPC064 Homo sapiens (Human) "decidualization [GO:0046697]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; oocyte growth [GO:0001555]; protein ubiquitination [GO:0016567]; rRNA processing [GO:0006364]" cell junction [GO:0030054]; centrosome [GO:0005813]; Cul4-RING E3 ubiquitin ligase complex [GO:0080008]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040] nuclear estrogen receptor binding [GO:0030331]; RNA binding [GO:0003723]; ubiquitin ligase-substrate adaptor activity [GO:1990756] 0.95983 -1.8131 AAKDYNQK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.95009 0 0 0 0 9.49053 0 0 0 0 0 0 9.85672 0 Q9NV12 TM140_HUMAN Transmembrane protein 140 TMEM140 Homo sapiens (Human) membrane [GO:0016020] 0.6466 0.39623 VGLGLAR 10.1411 10.0133 9.7608 0 0 0 9.64043 9.73573 9.8145 9.15406 9.38213 9.50567 0 0 0 0 10.0364 0 0 0 0 0 0 0 0 0 0 Q9NV23 SAST_HUMAN "S-acyl fatty acid synthase thioesterase, medium chain (EC 3.1.2.14) (Augmented in rheumatoid arthritis 1) (AURA1) (Oleoyl-ACP hydrolase) (Thioesterase 2) (TE2) (Thioesterase II) (Thioesterase domain-containing protein 1)" OLAH THEDC1 Homo sapiens (Human) lipid biosynthetic process [GO:0008610]; medium-chain fatty acid biosynthetic process [GO:0051792] cytosol [GO:0005829] dodecanoyl-[acyl-carrier-protein] hydrolase activity [GO:0047381]; myristoyl-[acyl-carrier-protein] hydrolase activity [GO:0016295]; myristoyl-CoA hydrolase activity [GO:0102991]; oleoyl-[acyl-carrier-protein] hydrolase activity [GO:0004320]; palmitoyl-[acyl-carrier-protein] hydrolase activity [GO:0016296]; palmitoyl-CoA hydrolase activity [GO:0016290] 0.95357 -1.5251 HFAEAKEFVK 0 0 0 0 0 0 0 0 8.25229 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NV31 IMP3_HUMAN U3 small nucleolar ribonucleoprotein protein IMP3 (U3 snoRNP protein IMP3) (BRMS2) IMP3 C15orf12 MRPS4 Homo sapiens (Human) maturation of SSU-rRNA [GO:0030490]; ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364] Mpp10 complex [GO:0034457]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; preribosome [GO:0030684]; small ribosomal subunit [GO:0015935]; small-subunit processome [GO:0032040] RNA binding [GO:0003723]; rRNA binding [GO:0019843]; snoRNA binding [GO:0030515]; structural constituent of ribosome [GO:0003735] 0.83629 0.19271 SMEDFVTWVDSSK 0 0 0 0 0 0 0 0 0 0 9.8897 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NV64 TM39A_HUMAN Transmembrane protein 39A TMEM39A SUSR2 Homo sapiens (Human) autophagy [GO:0006914]; negative regulation of autophagosome assembly [GO:1902902]; negative regulation of autophagosome maturation [GO:1901097]; positive regulation of viral genome replication [GO:0045070] endoplasmic reticulum membrane [GO:0005789] 0.96263 -2.0837 AYSYPLNSYELKAN 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4278 0 0 0 0 0 0 0 0 0 Q9NV70 EXOC1_HUMAN Exocyst complex component 1 (Exocyst complex component Sec3) EXOC1 SEC3 SEC3L1 BM-012 Homo sapiens (Human) defense response to virus [GO:0051607]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; membrane fission [GO:0090148]; mitotic cytokinesis [GO:0000281]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of protein secretion [GO:0050714]; protein transport [GO:0015031]; regulation of macroautophagy [GO:0016241]; vesicle docking involved in exocytosis [GO:0006904]; vesicle tethering involved in exocytosis [GO:0090522] cytoplasm [GO:0005737]; cytoplasmic side of apical plasma membrane [GO:0098592]; cytosol [GO:0005829]; exocyst [GO:0000145]; Flemming body [GO:0090543]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] "phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]" 0.96741 -2.8196 DIFTPNDERLLSIVNVCKAGK 0 0 0 0 0 0 0 0 0 0 0 0 0 11.7219 0 0 0 0 0 0 0 9.47547 0 0 0 0 9.35129 Q9NV72 ZN701_HUMAN Zinc finger protein 701 ZNF701 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.95585 -1.5477 AIHTGEKPYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.47131 0 0 0 Q9NV79 PCMD2_HUMAN Protein-L-isoaspartate O-methyltransferase domain-containing protein 2 PCMTD2 C20orf36 Homo sapiens (Human) protein modification process [GO:0036211] cytoplasm [GO:0005737] protein-L-isoaspartate (D-aspartate) O-methyltransferase activity [GO:0004719] 0.92399 -1.0282 ENAYKDLAWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0003 0 0 Q9NV92 NFIP2_HUMAN NEDD4 family-interacting protein 2 (NEDD4 WW domain-binding protein 5A) (Putative MAPK-activating protein PM04/PM05/PM06/PM07) (Putative NF-kappa-B-activating protein 413) NDFIP2 KIAA1165 N4WBP5A Homo sapiens (Human) metal ion transport [GO:0030001]; negative regulation of gene expression [GO:0010629]; negative regulation of protein transport [GO:0051224]; negative regulation of transporter activity [GO:0032410]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein ubiquitination [GO:0031398]; ubiquitin-dependent protein catabolic process [GO:0006511]; vacuolar transport [GO:0007034] cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; multivesicular body membrane [GO:0032585]; perinuclear region of cytoplasm [GO:0048471] WW domain binding [GO:0050699] 0.83459 0.19083 AAAMAAAAAETSQR 0 0 0 0 0 0 0 0 0 0 0 0 11.4554 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NVC6 MED17_HUMAN Mediator of RNA polymerase II transcription subunit 17 (Activator-recruited cofactor 77 kDa component) (ARC77) (Cofactor required for Sp1 transcriptional activation subunit 6) (CRSP complex subunit 6) (Mediator complex subunit 17) (Thyroid hormone receptor-associated protein complex 80 kDa component) (Trap80) (Transcriptional coactivator CRSP77) (Vitamin D3 receptor-interacting protein complex 80 kDa component) (DRIP80) MED17 ARC77 CRSP6 DRIP77 DRIP80 TRAP80 Homo sapiens (Human) positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; protein ubiquitination [GO:0016567]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA polymerase II preinitiation complex assembly [GO:0051123]; somatic stem cell population maintenance [GO:0035019]; transcription initiation at RNA polymerase II promoter [GO:0006367] core mediator complex [GO:0070847]; mediator complex [GO:0016592]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667]; ubiquitin ligase complex [GO:0000151] nuclear receptor coactivator activity [GO:0030374]; nuclear thyroid hormone receptor binding [GO:0046966]; nuclear vitamin D receptor binding [GO:0042809]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; ubiquitin protein ligase activity [GO:0061630] 0.96947 -4.9659 FQPSLWPWDSVR 0 0 0 8.54408 8.45828 0 0 0 0 0 12.3879 12.4334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NVD3 SETD4_HUMAN SET domain-containing protein 4 (EC 2.1.1.-) (EC 2.1.1.364) SETD4 C21orf18 C21orf27 Homo sapiens (Human) chromatin remodeling [GO:0006338]; inflammatory response [GO:0006954]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; peptidyl-lysine trimethylation [GO:0018023]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell proliferation in bone marrow [GO:0071863] cytosol [GO:0005829]; nucleus [GO:0005634] histone H3K36 methyltransferase activity [GO:0046975]; histone H3K4 methyltransferase activity [GO:0042800]; histone H3K4 monomethyltransferase activity [GO:0140945]; histone H4K20 methyltransferase activity [GO:0042799]; histone H4K20 monomethyltransferase activity [GO:0140944]; histone H4K20me methyltransferase activity [GO:0140941]; transcription coactivator activity [GO:0003713] 0.91742 -0.87256 GVNESHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2299 0 0 Q9NVE4 CCD87_HUMAN Coiled-coil domain-containing protein 87 CCDC87 Homo sapiens (Human) cell differentiation [GO:0030154]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of fertilization [GO:1905516]; single fertilization [GO:0007338]; spermatogenesis [GO:0007283] 0.96281 -2.1811 ELKSIPR 0 0 0 14.0831 0 10.6303 0 0 0 0 0 0 0 0 10.8784 15.1376 0 0 14.4412 0 14.1863 12.9049 0 0 0 0 0 Q9NVE5 UBP40_HUMAN Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.4.19.12) (Deubiquitinating enzyme 40) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) USP40 Homo sapiens (Human) protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] cytosol [GO:0005829]; nucleus [GO:0005634] cysteine-type deubiquitinase activity [GO:0004843]; cysteine-type endopeptidase activity [GO:0004197] 0.96955 -5.0797 EAELKMGSSLGLCLGK 0 0 0 0 0 0 0 9.337 10.517 0 0 0 9.73628 0 0 0 9.67717 11.2776 0 0 0 0 0 0 11.7222 10.0261 0 Q9NVF7 FBX28_HUMAN F-box only protein 28 FBXO28 CENP-30 KIAA0483 Homo sapiens (Human) protein polyubiquitination [GO:0000209] kinetochore [GO:0000776] identical protein binding [GO:0042802] 0.63045 0.40011 LSLLNMTFMK 0 0 0 0 0 0 0 11.6787 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6228 0 0 0 0 0 Q9NVF9 EKI2_HUMAN Ethanolamine kinase 2 (EKI 2) (EC 2.7.1.82) (Ethanolamine kinase-like protein) ETNK2 EKI2 HMFT1716 Homo sapiens (Human) in utero embryonic development [GO:0001701]; multicellular organism growth [GO:0035264]; phosphatidylethanolamine biosynthetic process [GO:0006646]; phosphorylation [GO:0016310]; placenta development [GO:0001890]; post-embryonic development [GO:0009791] cytoplasm [GO:0005737]; cytosol [GO:0005829] ATP binding [GO:0005524]; ethanolamine kinase activity [GO:0004305] 0.95273 -1.4936 LFRLIALEMAK 0 0 0 0 0 0 12.275 0 12.5595 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NVH0 EXD2_HUMAN Exonuclease 3'-5' domain-containing protein 2 (EC 3.1.11.1) (3'-5' exoribonuclease EXD2) (EC 3.1.13.-) (Exonuclease 3'-5' domain-like-containing protein 2) EXD2 C14orf114 EXDL2 Homo sapiens (Human) DNA double-strand break processing [GO:0000729]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; replication fork processing [GO:0031297] cytoplasm [GO:0005737]; intermediate filament cytoskeleton [GO:0045111]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; site of DNA damage [GO:0090734] 3'-5' exonuclease activity [GO:0008408]; 3'-5'-DNA exonuclease activity [GO:0008296]; 3'-5'-RNA exonuclease activity [GO:0000175]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleic acid binding [GO:0003676]; protein homodimerization activity [GO:0042803]; single-stranded DNA 3'-5' DNA exonuclease activity [GO:0008310] 0.88882 -0.42819 ENLCVVCGKR 0 0 10.0443 0 0 0 0 0 11.486 9.08645 0 0 9.96152 0 0 0 0 0 9.82354 9.86118 0 0 0 0 0 0 0 Q9NVH6 TMLH_HUMAN "Trimethyllysine dioxygenase, mitochondrial (EC 1.14.11.8) (Epsilon-trimethyllysine 2-oxoglutarate dioxygenase) (Epsilon-trimethyllysine hydroxylase) (TML hydroxylase) (TML-alpha-ketoglutarate dioxygenase) (TML dioxygenase) (TMLD)" TMLHE TMLH Homo sapiens (Human) carnitine biosynthetic process [GO:0045329]; negative regulation of oxidoreductase activity [GO:0051354] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] iron ion binding [GO:0005506]; trimethyllysine dioxygenase activity [GO:0050353] 0.84273 0.15187 HEGTGGR 0 0 0 0 0 0 0 0 0 0 0 9.61784 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NVI1 FANCI_HUMAN Fanconi anemia group I protein (Protein FACI) FANCI KIAA1794 Homo sapiens (Human) cell cycle [GO:0007049]; interstrand cross-link repair [GO:0036297]; positive regulation of protein ubiquitination [GO:0031398] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; DNA repair complex [GO:1990391]; membrane [GO:0016020]; nucleoplasm [GO:0005654] DNA binding [GO:0003677]; DNA polymerase binding [GO:0070182] 0.96939 -4.1079 ILSLAAEKTADKLQEFLQTLR 10.2188 0 9.73486 9.04117 11.0156 0 0 11.064 0 0 0 0 0 0 0 0 0 0 0 9.07318 0 0 10.8543 10.7393 0 0 0 Q9NVI7 ATD3A_HUMAN ATPase family AAA domain-containing protein 3A ATAD3A Homo sapiens (Human) antiviral innate immune response [GO:0140374]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; regulation of cell growth [GO:0001558] mitochondrial inner membrane [GO:0005743]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; identical protein binding [GO:0042802] 0.89855 -0.62542 ITVLEALR 13.3109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5371 8.66924 0 0 0 0 0 0 0 0 0 0 Q9NVL1 F86C1_HUMAN Putative protein FAM86C1P (EC 2.1.1.-) (Protein FAM86C) FAM86C1P FAM86C FAM86C1 Homo sapiens (Human) methylation [GO:0032259] protein-containing complex [GO:0032991] methyltransferase activity [GO:0008168] 0.61375 0.42465 WQSLEAK 0 0 0 0 0 0 0 0 0 12.3535 0 0 9.00941 0 0 9.30943 9.47669 9.35592 0 0 0 0 0 0 0 0 0 Q9NVM4 ANM7_HUMAN Protein arginine N-methyltransferase 7 (EC 2.1.1.321) (Histone-arginine N-methyltransferase PRMT7) ([Myelin basic protein]-arginine N-methyltransferase PRMT7) PRMT7 KIAA1933 Homo sapiens (Human) cell differentiation [GO:0030154]; peptidyl-arginine methylation [GO:0018216]; regulation of gene expression by genomic imprinting [GO:0006349]; regulation of protein binding [GO:0043393]; spliceosomal snRNP assembly [GO:0000387] cytosol [GO:0005829]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] histone binding [GO:0042393]; histone H4 methyltransferase activity [GO:0140939]; histone H4R3 methyltransferase activity [GO:0044020]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]; protein-arginine omega-N symmetric methyltransferase activity [GO:0035243]; ribonucleoprotein complex binding [GO:0043021]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757] 0.81258 0.2226 ATVYAQLVESGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.2879 Q9NVM6 DJC17_HUMAN DnaJ homolog subfamily C member 17 DNAJC17 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; spliceosomal complex disassembly [GO:0000390]; toxin transport [GO:1901998] cytoplasm [GO:0005737]; spliceosomal complex [GO:0005681] RNA binding [GO:0003723] 0.96956 -4.7233 EVKKAYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3852 0 0 0 8.69742 0 0 0 0 0 0 Q9NVM9 INT13_HUMAN Integrator complex subunit 13 (Cell cycle regulator Mat89Bb homolog) (Germ cell tumor 1) (Protein asunder homolog) (Sarcoma antigen NY-SAR-95) INTS13 ASUN C12orf11 GCT1 Homo sapiens (Human) cell division [GO:0051301]; centrosome localization [GO:0051642]; flagellated sperm motility [GO:0030317]; mitotic spindle organization [GO:0007052]; protein localization to nuclear envelope [GO:0090435]; regulation of fertilization [GO:0080154]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription elongation by RNA polymerase II [GO:0034243]; snRNA processing [GO:0016180] cytoplasm [GO:0005737]; integrator complex [GO:0032039]; intracellular membrane-bounded organelle [GO:0043231]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.96315 -2.4419 IMYDIFPFKK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.72772 0 0 0 0 0 0 0 0 10.2856 0 0 0 0 Q9NVN3 RIC8B_HUMAN Synembryn-B (Brain synembryn) (hSyn) (Protein Ric-8B) RIC8B Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of G protein-coupled receptor signaling pathway [GO:0008277] cell cortex [GO:0005938]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886] G-protein alpha-subunit binding [GO:0001965]; guanyl-nucleotide exchange factor activity [GO:0005085] 0.96778 -2.9456 GSSYREGLTPVLSLLTECSR 10.6181 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NVN8 GNL3L_HUMAN Guanine nucleotide-binding protein-like 3-like protein GNL3L Homo sapiens (Human) "negative regulation of protein binding [GO:0032091]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of telomere maintenance via telomerase [GO:0032211]; positive regulation of protein localization to chromosome, telomeric region [GO:1904816]; positive regulation of protein-containing complex assembly [GO:0031334]; regulation of protein stability [GO:0031647]; ribosome biogenesis [GO:0042254]" cytosol [GO:0005829]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; telomerase holoenzyme complex [GO:0005697] GTP binding [GO:0005525]; RNA binding [GO:0003723] 0.89854 -0.58128 IADAIENK 0 0 0 0 0 0 0 0 0 0 0 0 10.2318 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NVP1 DDX18_HUMAN ATP-dependent RNA helicase DDX18 (EC 3.6.4.13) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb) DDX18 cPERP-D Homo sapiens (Human) "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]" chromosome [GO:0005694]; membrane [GO:0016020]; nucleolus [GO:0005730] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.29704 0.81409 FLLLFTFLKKNR 0 0 12.5908 12.6844 12.6956 10.8925 11.4397 12.6355 0 0 8.7086 0 9.70726 0 0 0 0 0 0 0 0 0 0 0 10.6017 0 0 Q9NVP4 DZAN1_HUMAN Double zinc ribbon and ankyrin repeat-containing protein 1 DZANK1 C20orf12 C20orf84 Homo sapiens (Human) eye photoreceptor cell development [GO:0042462] metal ion binding [GO:0046872] 0.96714 -2.8657 AIAVSKDCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.32513 0 0 0 Q9NVR2 INT10_HUMAN Integrator complex subunit 10 (Int10) INTS10 C8orf35 Homo sapiens (Human) regulation of transcription elongation by RNA polymerase II [GO:0034243]; snRNA processing [GO:0016180] integrator complex [GO:0032039]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.9632 -2.6406 GVKEDFRLAMER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3515 0 0 0 0 0 0 0 0 0 Q9NVR5 KTU_HUMAN "Protein kintoun (Dynein assembly factor 2, axonemal)" DNAAF2 C14orf104 KTU Homo sapiens (Human) axonemal dynein complex assembly [GO:0070286]; cilium-dependent cell motility [GO:0060285]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of left/right asymmetry [GO:0061966]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; inner dynein arm assembly [GO:0036159]; outer dynein arm assembly [GO:0036158]; protein stabilization [GO:0050821]; response to retinoic acid [GO:0032526] cytoplasm [GO:0005737]; cytosol [GO:0005829]; dynein axonemal particle [GO:0120293]; extracellular region [GO:0005576]; protein folding chaperone complex [GO:0101031] 0.95494 -1.5367 GVEVRFVHPEPGHVLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1106 0 0 11.3961 0 0 0 0 0 0 0 0 0 Q9NVR7 TBCC1_HUMAN TBCC domain-containing protein 1 TBCCD1 Homo sapiens (Human) maintenance of centrosome location [GO:0051661]; maintenance of Golgi location [GO:0051684]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360] cytoplasm [GO:0005737]; spindle pole centrosome [GO:0031616] 0.92527 -0.96951 DLAWLYFEIFDSLSMK 0 0 0 0 0 0 0 0 0 9.97799 0 0 0 9.70715 0 0 0 10.5693 0 0 0 9.52452 0 9.43325 0 0 0 Q9NVS2 RT18A_HUMAN "Large ribosomal subunit protein mL66 (39S ribosomal protein S18-3, mitochondrial) (MRP-S18-3) (39S ribosomal protein S18a, mitochondrial) (MRP-S18-a) (Mrps18a) (S18mt-a) (Large ribosomal subunit protein bS18a)" MRPS18A Homo sapiens (Human) mitochondrial translation [GO:0032543]; translation [GO:0006412] mitochondrial inner membrane [GO:0005743]; mitochondrial large ribosomal subunit [GO:0005762]; mitochondrial small ribosomal subunit [GO:0005763]; mitochondrion [GO:0005739] small ribosomal subunit rRNA binding [GO:0070181]; structural constituent of ribosome [GO:0003735] 0.9613 -2.0557 GLLAGPAATSWSRLPAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.93452 0 0 0 0 0 0 0 0 0 0 Q9NVS9 PNPO_HUMAN Pyridoxine-5'-phosphate oxidase (EC 1.4.3.5) (Pyridoxamine-phosphate oxidase) PNPO Homo sapiens (Human) pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615] cytosol [GO:0005829] FMN binding [GO:0010181]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; pyridoxamine-phosphate oxidase activity [GO:0004733] 0.21589 0.89781 KLPEEEAECYFHSRPK 11.6364 11.4522 0 11.1289 11.3354 11.0909 11.4858 0 11.6065 11.8498 0 0 0 0 11.0093 0 0 0 0 0 0 0 0 0 0 0 0 Q9NVT9 ARMC1_HUMAN Armadillo repeat-containing protein 1 ARMC1 ARCP Homo sapiens (Human) intracellular distribution of mitochondria [GO:0048312] cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739] metal ion binding [GO:0046872] 0.88488 -0.22585 AEALASAIASTK 12.1638 0 12.2671 0 0 0 0 0 0 0 11.6596 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NVU0 RPC5_HUMAN DNA-directed RNA polymerase III subunit RPC5 (RNA polymerase III subunit C5) (DNA-directed RNA polymerase III 80 kDa polypeptide) POLR3E KIAA1452 Homo sapiens (Human) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; transcription by RNA polymerase III [GO:0006383] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; RNA polymerase III complex [GO:0005666] 0.95419 -1.5055 LEKVYNLVK 0 10.2596 10.3475 0 10.215 10.1577 11.9103 11.9992 11.9263 11.5928 11.5767 0 0 12.1295 12.1634 10.9452 0 0 0 0 0 0 0 0 0 0 10.7685 Q9NVU7 SDA1_HUMAN Protein SDA1 homolog (Nucleolar protein 130) (SDA1 domain-containing protein 1) (hSDA) SDAD1 NUC130 Homo sapiens (Human) protein transport [GO:0015031]; ribosomal large subunit biogenesis [GO:0042273]; ribosomal large subunit export from nucleus [GO:0000055] nucleolus [GO:0005730]; nucleoplasm [GO:0005654] 0.96292 -2.1841 LATAMAGKTDR 8.74019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.3289 12.0987 11.655 11.2393 11.3271 0 8.68954 11.4939 11.5319 12.1925 12.3022 Q9NVV2 CS073_HUMAN Putative uncharacterized protein C19orf73 C19orf73 Homo sapiens (Human) 0.50049 0.61182 VGFQGGGCFRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6053 0 0 Q9NVV9 THAP1_HUMAN THAP domain-containing protein 1 THAP1 Homo sapiens (Human) cell cycle [GO:0007049]; DNA-templated transcription [GO:0006351]; endothelial cell proliferation [GO:0001935]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]" 0.96899 -4.4915 ECNNKLLK 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0928 9.78614 0 0 0 0 0 0 0 0 0 0 0 0 Q9NVX2 NLE1_HUMAN Notchless protein homolog 1 NLE1 HUSSY-07 Homo sapiens (Human) hematopoietic stem cell homeostasis [GO:0061484]; inner cell mass cell differentiation [GO:0001826]; kidney development [GO:0001822]; mitotic cell cycle [GO:0000278]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of mitotic cell cycle [GO:0045930]; Notch signaling pathway [GO:0007219]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; ribosomal large subunit assembly [GO:0000027]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756] nucleolus [GO:0005730]; nucleoplasm [GO:0005654] 0.92168 -0.9364 DKCLRIWR 0 0 0 0 0 0 0 0 9.27873 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NVX7 KBTB4_HUMAN Kelch repeat and BTB domain-containing protein 4 (BTB and kelch domain-containing protein 4) KBTBD4 BKLHD4 Homo sapiens (Human) 0.84119 0.18199 EAFAESLR 0 0 0 8.87067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NW08 RPC2_HUMAN DNA-directed RNA polymerase III subunit RPC2 (RNA polymerase III subunit C2) (EC 2.7.7.6) (C128) (DNA-directed RNA polymerase III 127.6 kDa polypeptide) (DNA-directed RNA polymerase III subunit B) POLR3B Homo sapiens (Human) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728]; transcription by RNA polymerase III [GO:0006383] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; RNA polymerase III complex [GO:0005666] DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; metal ion binding [GO:0046872]; ribonucleoside binding [GO:0032549] 0.97016 -5.1824 GPRAVLTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.66124 0 0 0 0 0 0 Q9NW13 RBM28_HUMAN RNA-binding protein 28 (RNA-binding motif protein 28) RBM28 Homo sapiens (Human) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] nucleolus [GO:0005730]; spliceosomal complex [GO:0005681] RNA binding [GO:0003723] 0.95956 -1.7553 AVQVSNK 0 0 0 7.98168 0 0 0 0 0 10.8751 0 0 0 9.34607 0 0 0 9.51118 0 9.2498 0 0 0 9.5745 0 10.8222 0 Q9NW15 ANO10_HUMAN Anoctamin-10 (Transmembrane protein 16K) ANO10 TMEM16K Homo sapiens (Human) chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; monoatomic cation transport [GO:0006812]; monoatomic ion transmembrane transport [GO:0034220] intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; plasma membrane [GO:0005886] calcium activated cation channel activity [GO:0005227]; chloride channel activity [GO:0005254]; intracellular calcium activated chloride channel activity [GO:0005229] 0.84108 0.14425 LEDTWYTR 0 0 0 0 0 0 10.1816 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NW64 RBM22_HUMAN Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22) (Zinc finger CCCH domain-containing protein 16) RBM22 ZC3H16 199G4 Homo sapiens (Human) "cellular response to xenobiotic stimulus [GO:0071466]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of RNA splicing [GO:0033120]" catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Prp19 complex [GO:0000974]; U2-type catalytic step 1 spliceosome [GO:0071006]; U2-type catalytic step 2 spliceosome [GO:0071007] calcium-dependent protein binding [GO:0048306]; metal ion binding [GO:0046872]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; U6 snRNA binding [GO:0017070] 0.96329 -2.6548 LDPPEDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2682 Q9NW68 BSDC1_HUMAN BSD domain-containing protein 1 BSDC1 UNQ2494/PRO5781 Homo sapiens (Human) cytoplasm [GO:0005737] 0.57533 0.47575 LATEGSSGATEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2807 0 0 0 0 0 Q9NW75 GPTC2_HUMAN G patch domain-containing protein 2 GPATCH2 GPATC2 Homo sapiens (Human) nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634] nucleic acid binding [GO:0003676] 0.96293 -2.1646 LHGMSSK 0 0 0 0 9.88266 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.94761 Q9NW81 DMAC2_HUMAN Distal membrane-arm assembly complex protein 2 (ATP synthase subunit s-like protein) DMAC2 ATP5SL Homo sapiens (Human) mitochondrial respiratory chain complex I assembly [GO:0032981]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] mitochondrion [GO:0005739]; SCF ubiquitin ligase complex [GO:0019005] 0.86297 0.090297 LVAPMWNGR 8.25597 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NW82 WDR70_HUMAN WD repeat-containing protein 70 WDR70 Homo sapiens (Human) nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861] enzyme binding [GO:0019899] 0.96304 -2.1473 EKEEEMNR 0 0 9.43505 0 0 0 9.00848 0 9.01709 0 0 0 0 0 0 8.09286 9.04617 9.1954 0 0 0 0 0 0 0 0 0 Q9NWB7 IFT57_HUMAN Intraflagellar transport protein 57 homolog (Dermal papilla-derived protein 8) (Estrogen-related receptor beta-like protein 1) (HIP1-interacting protein) (MHS4R2) IFT57 DERP8 ESRRBL1 HIPPI Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cilium assembly [GO:0060271]; heart looping [GO:0001947]; intraciliary anterograde transport [GO:0035720]; intraciliary transport [GO:0042073]; keratinocyte proliferation [GO:0043616]; motile cilium assembly [GO:0044458]; negative regulation of keratinocyte proliferation [GO:0010839]; neural tube closure [GO:0001843]; non-motile cilium assembly [GO:1905515]; regulation of apoptotic process [GO:0042981]; smoothened signaling pathway [GO:0007224] axoneme [GO:0005930]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary base [GO:0097546]; ciliary tip [GO:0097542]; cilium [GO:0005929]; dendrite terminus [GO:0044292]; Golgi apparatus [GO:0005794]; intraciliary transport particle B [GO:0030992]; photoreceptor connecting cilium [GO:0032391] DNA binding [GO:0003677] 0.88466 -0.13589 TADFPPSK 0 0 9.35083 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NWF9 RN216_HUMAN E3 ubiquitin-protein ligase RNF216 (EC 2.3.2.27) (RING finger protein 216) (RING-type E3 ubiquitin transferase RNF216) (Triad domain-containing protein 3) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) RNF216 TRIAD3 UBCE7IP1 ZIN Homo sapiens (Human) apoptotic process [GO:0006915]; negative regulation of type I interferon production [GO:0032480]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; regulation of defense response to virus by host [GO:0050691]; regulation of interferon-beta production [GO:0032648] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630] 0.92416 -1.0343 EAEEEQKRK 0 8.48901 8.9849 0 0 9.26301 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.57244 0 0 9.58301 0 0 0 Q9NWH7 SPAT6_HUMAN Spermatogenesis-associated protein 6 SPATA6 Homo sapiens (Human) cell differentiation [GO:0030154]; motile cilium assembly [GO:0044458]; spermatogenesis [GO:0007283] extracellular region [GO:0005576]; sperm connecting piece [GO:0097224] myosin light chain binding [GO:0032027] 0.89838 -0.65371 LAHLNLGPYEFK 0 0 0 0 9.88416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.97312 0 Q9NWH9 SLTM_HUMAN SAFB-like transcription modulator (Modulator of estrogen-induced transcription) SLTM MET Homo sapiens (Human) apoptotic process [GO:0006915]; regulation of mRNA processing [GO:0050684]; regulation of transcription by RNA polymerase II [GO:0006357] nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] RNA binding [GO:0003723]; sequence-specific DNA binding [GO:0043565] 0.96902 -4.5448 DVDHRRDDPYWSENK 0 0 0 0 0 0 0 10.5038 0 0 0 10.981 0 0 0 0 0 0 0 0 11.6535 10.7022 9.52066 0 0 9.28385 0 Q9NWL6 ASND1_HUMAN Asparagine synthetase domain-containing protein 1 (HCV NS3-transactivated protein 1) ASNSD1 NS3TP1 Nbla00058 Homo sapiens (Human) asparagine biosynthetic process [GO:0006529]; glutamine metabolic process [GO:0006541] asparagine synthase (glutamine-hydrolyzing) activity [GO:0004066] 0.95829 -1.68 GVLTTQPVEDER 0 0 0 0 8.94181 9.28797 0 0 0 0 0 10.3156 0 0 0 9.34935 0 0 0 0 0 0 0 0 0 0 0 Q9NWM8 FKB14_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP14 (PPIase FKBP14) (EC 5.2.1.8) (22 kDa FK506-binding protein) (22 kDa FKBP) (FKBP-22) (FK506-binding protein 14) (FKBP-14) (Rotamase) FKBP14 FKBP22 UNQ322/PRO381 Homo sapiens (Human) endoplasmic reticulum lumen [GO:0005788] calcium ion binding [GO:0005509]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755] 0.89653 -0.54016 DGFISAREFTYK 0 0 0 14.7399 14.7984 0 0 0 9.94398 0 0 0 13.5203 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NWN3 FBX34_HUMAN F-box only protein 34 FBXO34 FBX34 Homo sapiens (Human) 0.92279 -1.1516 EDPCKQCK 0 0 0 0 0 0 0 0 0 0 8.97094 0 9.96723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NWQ4 GPT2L_HUMAN G patch domain-containing protein 2-like GPATCH2L C14orf118 KIAA1152 Homo sapiens (Human) nucleus [GO:0005634] 0.86925 0.057832 LGELWEEMALSPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.08388 0 0 0 0 0 0 Q9NWR8 MCUB_HUMAN "Calcium uniporter regulatory subunit MCUb, mitochondrial (MCUb) (Coiled-coil domain-containing protein 109B)" MCUB CCDC109B Homo sapiens (Human) calcium import into the mitochondrion [GO:0036444]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transmembrane transport [GO:0006851] calcium channel complex [GO:0034704]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; uniplex complex [GO:1990246] calcium channel inhibitor activity [GO:0019855] 0.60624 0.43648 IAYDVQCPK 0 0 0 0 0 0 10.42 10.765 0 0 0 0 0 0 0 0 0 0 9.36759 9.51779 9.48718 9.57442 0 0 0 0 0 Q9NWS1 PARI_HUMAN PCNA-interacting partner (PARI) (PARP-1 binding protein) (PARP1-binding protein) (PARPBP) PARPBP C12orf48 PARI Homo sapiens (Human) DNA repair [GO:0006281]; negative regulation of double-strand break repair via homologous recombination [GO:2000042] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654] DNA binding [GO:0003677] 0.96951 -3.5915 ICVSMQEKK 11.5047 11.3506 11.0759 10.0568 10.0958 12.4708 11.1478 12.3594 12.2248 0 0 0 10.563 10.5517 10.343 10.8397 11.1447 11.0008 0 0 9.02495 0 0 0 0 0 0 Q9NWS8 RMND1_HUMAN Required for meiotic nuclear division protein 1 homolog RMND1 C6orf96 Homo sapiens (Human) positive regulation of mitochondrial translation [GO:0070131]; translation [GO:0006412] mitochondrion [GO:0005739] 0.77677 0.26394 EGAAVFWNVKDK 0 0 0 0 0 0 0 0 0 0 12.8271 0 0 8.29733 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NWV4 CZIB_HUMAN CXXC motif containing zinc binding protein (UPF0587 protein C1orf123) CZIB C1orf123 Homo sapiens (Human) zinc ion binding [GO:0008270] 0.8214 0.21738 CGNCGEISDK 0 0 0 0 0 0 0 9.89564 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NWW7 CB042_HUMAN Uncharacterized protein C2orf42 C2orf42 Homo sapiens (Human) nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.92653 -1.215 DGTYELFKCPK 0 0 0 0 0 0 0 0 0 0 0 0 10.8284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NWX6 THG1_HUMAN Probable tRNA(His) guanylyltransferase (EC 2.7.7.79) (Induced in high glucose-1) (IHG-1) (Interphase cytoplasmic foci protein 45) (tRNA-histidine guanylyltransferase) THG1L ICF45 Homo sapiens (Human) mitochondrial fusion [GO:0008053]; protein homotetramerization [GO:0051289]; response to oxidative stress [GO:0006979]; stress-induced mitochondrial fusion [GO:1990046]; tRNA modification [GO:0006400]; tRNA processing [GO:0008033] cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; transferase complex [GO:1990234] ATP binding [GO:0005524]; GTP binding [GO:0005525]; guanyl-nucleotide exchange factor activity [GO:0005085]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleotidyltransferase activity [GO:0016779]; tRNA binding [GO:0000049]; tRNA guanylyltransferase activity [GO:0008193] 0.92202 -1.0903 LDGRNFHR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.86743 0 0 0 0 9.56786 0 0 0 0 0 0 10.0175 0 Q9NWY4 HPF1_HUMAN Histone PARylation factor 1 HPF1 C4orf27 Homo sapiens (Human) DNA damage response [GO:0006974]; DNA repair [GO:0006281]; DNA repair-dependent chromatin remodeling [GO:0140861]; double-strand break repair [GO:0006302]; regulation of histone modification [GO:0031056]; regulation of protein ADP-ribosylation [GO:0010835] chromatin [GO:0000785]; nucleus [GO:0005634]; site of DNA damage [GO:0090734] chromatin binding [GO:0003682]; enzyme activator activity [GO:0008047]; histone binding [GO:0042393]; poly-ADP-D-ribose binding [GO:0072572]; protein ADP-ribosyltransferase-substrate adaptor activity [GO:0140768] 0.88404 -0.10881 ELGYSLEQRTVKMK 0 12.3136 9.73797 0 0 10.8588 8.30469 0 12.6471 0 10.1538 12.8529 9.96049 10.0073 10.3482 0 9.70694 0 0 0 8.8649 0 9.12309 0 0 0 9.6805 Q9NWZ3 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-64) IRAK4 Homo sapiens (Human) cytokine-mediated signaling pathway [GO:0019221]; innate immune response [GO:0045087]; interleukin-1-mediated signaling pathway [GO:0070498]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; neutrophil mediated immunity [GO:0002446]; neutrophil migration [GO:1990266]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein phosphorylation [GO:0006468]; toll-like receptor 9 signaling pathway [GO:0034162]; toll-like receptor signaling pathway [GO:0002224] cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; nucleus [GO:0005634]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; interleukin-1 receptor binding [GO:0005149]; kinase activator activity [GO:0019209]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; protein kinase binding [GO:0019901]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.80181 0.23941 VQQLLQEMTAS 0 0 0 0 0 0 0 0 0 0 8.81327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NWZ5 UCKL1_HUMAN Uridine-cytidine kinase-like 1 (EC 2.7.1.48) UCKL1 URKL1 F538 Homo sapiens (Human) CTP salvage [GO:0044211]; phosphorylation [GO:0016310]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] ATP binding [GO:0005524]; uridine kinase activity [GO:0004849] 0.53996 0.57963 GMHTIIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.9379 0 0 0 0 9.15175 0 0 0 Q9NX02 NALP2_HUMAN "NACHT, LRR and PYD domains-containing protein 2 (Nucleotide-binding site protein 1) (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2)" NLRP2 NALP2 NBS1 PAN1 PYPAF2 Homo sapiens (Human) apoptotic process [GO:0006915]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of interleukin-1 beta production [GO:0032731]; regulation of inflammatory response [GO:0050727] cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231] ATP binding [GO:0005524]; Pyrin domain binding [GO:0032090] 0.73758 0.3253 ELTHLCLAKNPIGNTGVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.03571 0 0 0 0 9.84183 0 0 0 10.6183 0 Q9NX05 F120C_HUMAN Constitutive coactivator of PPAR-gamma-like protein 2 (Protein FAM120C) (Tumor antigen BJ-HCC-21) FAM120C CXorf17 Homo sapiens (Human) nucleus [GO:0005634] RNA binding [GO:0003723] 0.95973 -1.814 AVEDKNRR 0 0 0 0 0 0 0 0 0 0 10.1337 10.5166 0 0 0 9.77924 0 0 0 9.83423 9.56836 0 0 0 0 0 0 Q9NX20 RM16_HUMAN "Large ribosomal subunit protein uL16m (39S ribosomal protein L16, mitochondrial) (L16mt) (MRP-L16)" MRPL16 PNAS-111 Homo sapiens (Human) mitochondrial translation [GO:0032543] mitochondrial inner membrane [GO:0005743]; mitochondrial large ribosomal subunit [GO:0005762]; mitochondrion [GO:0005739] rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735] 0.56595 0.49124 IATANMLGIR 0 0 0 0 11.0156 10.8612 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3723 0 0 Q9NX36 DJC28_HUMAN DnaJ homolog subfamily C member 28 DNAJC28 C21orf55 C21orf78 Homo sapiens (Human) 0.92588 -1.21 GEEEEDVEKFK 0 0 0 0 0 8.87918 0 0 0 9.42968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NX40 OCAD1_HUMAN OCIA domain-containing protein 1 (Ovarian cancer immunoreactive antigen domain containing 1) (Ovarian carcinoma immunoreactive antigen) OCIAD1 ASRIJ OCIA Homo sapiens (Human) endocytosis [GO:0006897]; hematopoietic stem cell homeostasis [GO:0061484]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of stem cell differentiation [GO:2000736] endosome [GO:0005768]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; membrane [GO:0016020] 0.63041 0.40297 NITYEELR 0 0 0 0 0 0 0 10.1795 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9752 0 Q9NX47 MARH5_HUMAN E3 ubiquitin-protein ligase MARCHF5 (EC 2.3.2.27) (Membrane-associated RING finger protein 5) (Membrane-associated RING-CH protein V) (MARCH-V) (Mitochondrial ubiquitin ligase) (MITOL) (RING finger protein 153) (RING-type E3 ubiquitin transferase MARCHF5) MARCHF5 MARCH5 RNF153 Homo sapiens (Human) positive regulation of mitochondrial fission [GO:0090141]; protein autoubiquitination [GO:0051865]; protein localization to mitochondrion [GO:0070585]; protein polyubiquitination [GO:0000209]; regulation of mitochondrial fission [GO:0090140] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739] GTPase binding [GO:0051020]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.87432 0.022762 PDQALQQMLDR 0 0 0 0 0 8.01117 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NX52 RHBL2_HUMAN "Rhomboid-related protein 2 (RRP2) (EC 3.4.21.105) (Rhomboid-like protein 2) [Cleaved into: Rhomboid-related protein 2, N-terminal fragment (NTF); Rhomboid-related protein 2, C-terminal fragment (CTF)]" RHBDL2 Homo sapiens (Human) proteolysis [GO:0006508] plasma membrane [GO:0005886] serine-type endopeptidase activity [GO:0004252] 0.95103 -1.4124 EMKEELEEEEK 0 0 0 0 0 9.80938 0 0 10.2968 0 0 0 0 0 10.6858 0 0 0 0 0 0 0 0 9.54431 0 0 10.9987 Q9NX57 RAB20_HUMAN Ras-related protein Rab-20 RAB20 Homo sapiens (Human) cellular response to type II interferon [GO:0071346]; intracellular protein transport [GO:0006886]; phagosome acidification [GO:0090383]; phagosome-lysosome fusion [GO:0090385] endomembrane system [GO:0012505]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; phagocytic vesicle [GO:0045335]; phagocytic vesicle membrane [GO:0030670] GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.8704 0.054097 GAAAIILTYDVNHR 0 9.36477 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NX58 LYAR_HUMAN Cell growth-regulating nucleolar protein LYAR PNAS-5 Homo sapiens (Human) erythrocyte development [GO:0048821]; innate immune response [GO:0045087]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of phagocytosis [GO:0050766]; positive regulation of transcription by RNA polymerase I [GO:0045943]; rRNA processing [GO:0006364] cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; photoreceptor outer segment [GO:0001750] DNA binding [GO:0003677]; DNA-binding transcription factor binding [GO:0140297]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; transcription regulator inhibitor activity [GO:0140416] 0.93425 -1.2895 ISKNPTFK 10.5788 0 0 0 0 0 0 0 10.5513 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NX61 T161A_HUMAN Transmembrane protein 161A (Adaptive response to oxidative stress protein 29) (AROS-29) TMEM161A UNQ582/PRO1152 Homo sapiens (Human) cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; positive regulation of DNA repair [GO:0045739]; response to retinoic acid [GO:0032526] membrane [GO:0016020] 0.80318 0.24086 WLLCNGSLFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5279 10.5809 0 0 0 0 0 0 0 0 0 0 Q9NX63 MIC19_HUMAN MICOS complex subunit MIC19 (Coiled-coil-helix-coiled-coil-helix domain-containing protein 3) CHCHD3 MIC19 MINOS3 Homo sapiens (Human) cristae formation [GO:0042407]; inner mitochondrial membrane organization [GO:0007007]; mitochondrial fusion [GO:0008053] extracellular exosome [GO:0070062]; MIB complex [GO:0140275]; MICOS complex [GO:0061617]; mitochondrial crista junction [GO:0044284]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; SAM complex [GO:0001401] molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902] 0.70804 0.36907 LSENVIDR 9.12322 0 0 0 0 0 0 0 0 9.53251 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NX65 ZSC32_HUMAN Zinc finger and SCAN domain-containing protein 32 (Human cervical cancer suppressor gene 5 protein) (HCCS-5) (Zinc finger protein 434) ZSCAN32 ZNF434 HCCS5 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.87064 0.049269 QEVQPEEPTFK 0 0 0 0 0 0 0 0 0 0 0 0 9.31075 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NX70 MED29_HUMAN Mediator of RNA polymerase II transcription subunit 29 (Intersex-like protein) (Mediator complex subunit 29) MED29 IXL Homo sapiens (Human) positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA polymerase II preinitiation complex assembly [GO:0051123] core mediator complex [GO:0070847]; mediator complex [GO:0016592]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] transcription coregulator activity [GO:0003712] 0.87097 0.028397 LAHECLSQSCDSAK 0 0 0 0 0 11.3839 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NX74 DUS2L_HUMAN tRNA-dihydrouridine(20) synthase [NAD(P)+]-like (EC 1.3.1.91) (Dihydrouridine synthase 2) (Up-regulated in lung cancer protein 8) (URLC8) (tRNA-dihydrouridine synthase 2-like) (hDUS2) DUS2 DUS2L Homo sapiens (Human) antiviral innate immune response [GO:0140374]; tRNA dihydrouridine synthesis [GO:0002943] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783] double-stranded RNA binding [GO:0003725]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; NADPH binding [GO:0070402]; protein kinase inhibitor activity [GO:0004860]; tRNA binding [GO:0000049]; tRNA dihydrouridine synthase activity [GO:0017150]; tRNA-dihydrouridine20 synthase activity [GO:0102264] 0.88265 -0.27206 LVENDVAGIDVNMGCPK 0 0 0 0 0 0 9.71179 0 0 0 0 0 0 0 0 0 10.0732 0 0 0 0 0 0 0 0 0 0 Q9NXB0 MKS1_HUMAN Tectonic-like complex member MKS1 (Meckel syndrome type 1 protein) MKS1 Homo sapiens (Human) "branching morphogenesis of an epithelial tube [GO:0048754]; cardiac septum morphogenesis [GO:0060411]; cilium assembly [GO:0060271]; common bile duct development [GO:0061009]; determination of left/right symmetry [GO:0007368]; embryonic brain development [GO:1990403]; embryonic digit morphogenesis [GO:0042733]; embryonic skeletal system development [GO:0048706]; epithelial structure maintenance [GO:0010669]; head development [GO:0060322]; inner ear receptor cell stereocilium organization [GO:0060122]; motile cilium assembly [GO:0044458]; neural tube closure [GO:0001843]; non-motile cilium assembly [GO:1905515]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901620]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation [GO:0003271]" centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; MKS complex [GO:0036038] 0.96105 -2.5603 LENSGGK 0 0 0 0 0 0 0 0 0 0 0 8.94951 0 0 0 0 0 0 0 0 0 8.63739 0 0 0 0 0 Q9NXC5 MIO_HUMAN GATOR complex protein MIOS (Missing oocyte meiosis regulator homolog) MIOS Homo sapiens (Human) cellular response to amino acid starvation [GO:0034198]; negative regulation of TORC1 signaling [GO:1904262]; positive regulation of TOR signaling [GO:0032008]; positive regulation of TORC1 signaling [GO:1904263]; protein-containing complex localization [GO:0031503] cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; GATOR2 complex [GO:0061700]; lysosomal membrane [GO:0005765]; nucleoplasm [GO:0005654] 0.89865 -0.55658 DLIGKEFVPKHAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.60235 0 0 0 0 0 0 0 0 0 0 0 0 Q9NXD2 MTMRA_HUMAN Myotubularin-related protein 10 (Inactive phosphatidylinositol 3-phosphatase 10) MTMR10 Homo sapiens (Human) cytoplasm [GO:0005737]; cytosol [GO:0005829] 0.96865 -3.8541 IDQRICNAITK 0 0 0 0 0 0 0 0 0 0 0 0 8.87166 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NXE4 NSMA3_HUMAN Sphingomyelin phosphodiesterase 4 (EC 3.1.4.12) (Neutral sphingomyelinase 3) (nSMase-3) (nSMase3) (Neutral sphingomyelinase III) SMPD4 KIAA1418 SKNY Homo sapiens (Human) cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; endoplasmic reticulum organization [GO:0007029]; glycerophospholipid catabolic process [GO:0046475]; sphingomyelin catabolic process [GO:0006685] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nuclear envelope [GO:0005635]; nuclear outer membrane [GO:0005640]; sarcolemma [GO:0042383]; trans-Golgi network [GO:0005802] metal ion binding [GO:0046872]; sphingomyelin phosphodiesterase activity [GO:0004767]; sphingomyelin phosphodiesterase D activity [GO:0050290] 0.91413 -0.82549 ALRTDLVSPK 0 0 0 0 0 0 0 8.64544 0 0 0 0 0 0 0 0 0 0 8.67832 10.2446 0 0 0 8.9364 0 0 0 Q9NXE8 CWC25_HUMAN Pre-mRNA-splicing factor CWC25 homolog (Coiled-coil domain-containing protein 49) (Spliceosome-associated protein homolog CWC25) CWC25 CCDC49 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]" nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type catalytic step 1 spliceosome [GO:0071006]; U2-type spliceosomal complex [GO:0005684] 0.87198 0.061361 QEMMENAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.71346 0 8.1822 0 0 0 0 0 0 0 0 0 0 Q9NXF8 ZDHC7_HUMAN Palmitoyltransferase ZDHHC7 (EC 2.3.1.225) (Acyltransferase ZDHHC7) (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 7) (DHHC-7) ZDHHC7 Homo sapiens (Human) androgen receptor signaling pathway [GO:0030521]; glucose import in response to insulin stimulus [GO:0044381]; negative regulation of catabolic process [GO:0009895]; peptidyl-L-cysteine S-palmitoylation [GO:0018230]; polarized epithelial cell differentiation [GO:0030859]; progesterone receptor signaling pathway [GO:0050847]; protein localization to plasma membrane [GO:0072659]; protein palmitoylation [GO:0018345]; protein targeting to membrane [GO:0006612]; regulation of Fas signaling pathway [GO:1902044]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; regulation of protein localization to cell-cell junction [GO:0150106]; regulation of protein localization to plasma membrane [GO:1903076]; steroid hormone mediated signaling pathway [GO:0043401] endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654] palmitoyltransferase activity [GO:0016409]; protein-cysteine S-myristoyltransferase activity [GO:0019705]; protein-cysteine S-palmitoyltransferase activity [GO:0019706]; protein-cysteine S-stearoyltransferase activity [GO:0140439] 0.88662 -0.35528 KMDHHCPWVNNCVGEK 0 0 0 0 0 0 0 0 0 10.0488 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NXG0 CNTLN_HUMAN Centlein (Centrosomal protein) CNTLN C9orf101 C9orf39 Homo sapiens (Human) centriole-centriole cohesion [GO:0010457]; protein localization to organelle [GO:0033365] centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654] protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein-macromolecule adaptor activity [GO:0030674] 0.96436 -2.3819 KERLQMLQTNYR 0 10.3545 10.5721 0 0 15.3589 0 0 0 0 0 9.40623 8.59406 10.8567 14.7648 0 15.4691 13.0186 0 0 0 0 0 0 0 9.0517 0 Q9NXG2 THUM1_HUMAN THUMP domain-containing protein 1 THUMPD1 Homo sapiens (Human) tRNA modification [GO:0006400] nucleoplasm [GO:0005654] RNA binding [GO:0003723] 0.91446 -0.80377 AFLEDMKK 0 0 0 0 0 0 0 0 0 0 10.2268 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NXG6 P4HTM_HUMAN Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4) P4HTM PH4 Homo sapiens (Human) peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; regulation of erythrocyte differentiation [GO:0045646] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789] 2-oxoglutarate-dependent dioxygenase activity [GO:0016706]; calcium ion binding [GO:0005509]; iron ion binding [GO:0005506]; L-ascorbic acid binding [GO:0031418]; procollagen-proline 4-dioxygenase activity [GO:0004656] 0.83632 0.18867 AESSELVR 0 0 0 0 0 0 0 0 0 10.4434 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NXH9 TRM1_HUMAN "tRNA (guanine(26)-N(2))-dimethyltransferase (EC 2.1.1.216) (tRNA 2,2-dimethylguanosine-26 methyltransferase) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase)" TRMT1 Homo sapiens (Human) tRNA modification [GO:0006400]; tRNA N2-guanine methylation [GO:0002940] nucleoplasm [GO:0005654]; nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA binding [GO:0003723]; tRNA (guanine-N2-)-methyltransferase activity [GO:0004809]; tRNA binding [GO:0000049] 0.8347 0.18779 LGKASGVPSGR 0 0 0 0 0 0 0 0 0 9.233 0 0 0 0 0 10.7738 0 0 8.7362 0 0 0 0 0 0 0 0 Q9NXI6 RN186_HUMAN E3 ubiquitin-protein ligase RNF186 (EC 2.3.2.27) (RING finger protein 186) RNF186 Homo sapiens (Human) intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K29-linked ubiquitination [GO:0035519]; protein K63-linked ubiquitination [GO:0070534]; protein localization to mitochondrion [GO:0070585]; regulation of autophagosome assembly [GO:2000785] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789] metal ion binding [GO:0046872]; molecular function activator activity [GO:0140677]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842] 0.92154 -1.1127 TLFCREQK 0 0 0 0 0 0 10.4734 0 0 0 0 13.0466 0 0 9.22197 0 10.8137 0 0 0 0 9.23795 0 9.59313 0 9.37217 0 Q9NXK8 FXL12_HUMAN F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12) FBXL12 FBL12 Homo sapiens (Human) protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] cytosol [GO:0005829]; SCF ubiquitin ligase complex [GO:0019005] 0.96753 -2.3365 ISRVCHR 0 0 0 0 0 0 0 0 8.63586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NXL2 ARH38_HUMAN Rho guanine nucleotide exchange factor 38 ARHGEF38 Homo sapiens (Human) cytoplasm [GO:0005737]; cytosol [GO:0005829] guanyl-nucleotide exchange factor activity [GO:0005085] 0.96338 -2.6553 DNTFNREEK 0 0 0 0 9.94479 9.94575 0 9.61989 9.69942 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NXL6 SIDT1_HUMAN SID1 transmembrane family member 1 SIDT1 Homo sapiens (Human) membrane [GO:0016020] cholesterol binding [GO:0015485]; RNA binding [GO:0003723]; RNA transmembrane transporter activity [GO:0051033] 0.34837 0.76857 LLVTKLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4712 0 0 0 9.58727 0 10.0393 0 0 0 0 0 0 Q9NXL9 MCM9_HUMAN DNA helicase MCM9 (hMCM9) (EC 3.6.4.12) (Mini-chromosome maintenance deficient domain-containing protein 1) (Minichromosome maintenance 9) MCM9 C6orf61 MCMDC1 Homo sapiens (Human) DNA damage response [GO:0006974]; DNA duplex unwinding [GO:0032508]; double-strand break repair via homologous recombination [GO:0000724]; female gamete generation [GO:0007292]; mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication [GO:0070716]; protein localization to chromatin [GO:0071168]; recombinational interstrand cross-link repair [GO:0036298] chromosome [GO:0005694]; MCM complex [GO:0042555]; MCM8-MCM9 complex [GO:0097362]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; chromatin binding [GO:0003682]; DNA helicase activity [GO:0003678]; enzyme binding [GO:0019899]; MutLbeta complex binding [GO:0032406]; MutSalpha complex binding [GO:0032407]; MutSbeta complex binding [GO:0032408]; protein-containing complex binding [GO:0044877]; single-stranded DNA binding [GO:0003697] 0.96885 -3.5969 NLQKLCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4885 0 0 0 0 0 0 0 10.2051 0 Q9NXN4 GDAP2_HUMAN Ganglioside-induced differentiation-associated protein 2 GDAP2 Homo sapiens (Human) response to retinoic acid [GO:0032526] lysosomal membrane [GO:0005765] 0.75902 0.30221 WLCQARSEDLSDIASLK 0 0 0 0 0 0 0 0 0 0 12.2469 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NXR1 NDE1_HUMAN Nuclear distribution protein nudE homolog 1 (NudE) NDE1 NUDE Homo sapiens (Human) cell division [GO:0051301]; cell migration [GO:0016477]; centrosome duplication [GO:0051298]; centrosome localization [GO:0051642]; cerebral cortex development [GO:0021987]; chromosome segregation [GO:0007059]; establishment of chromosome localization [GO:0051303]; establishment of mitotic spindle orientation [GO:0000132]; microtubule nucleation [GO:0007020]; mitotic centrosome separation [GO:0007100]; neuroblast proliferation [GO:0007405]; neuron migration [GO:0001764]; vesicle transport along microtubule [GO:0047496] centrosome [GO:0005813]; cleavage furrow [GO:0032154]; cytosol [GO:0005829]; kinesin complex [GO:0005871]; kinetochore [GO:0000776]; membrane [GO:0016020]; microtubule [GO:0005874]; spindle pole centrosome [GO:0031616]; synapse [GO:0045202] identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protein domain specific binding [GO:0019904] 0.95427 -1.5127 DLAMTYKQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.34336 0 0 0 Q9NXR8 ING3_HUMAN Inhibitor of growth protein 3 (p47ING3) ING3 HSPC301 Homo sapiens (Human) histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of DNA-templated transcription [GO:0006355]; regulation of double-strand break repair [GO:2000779] NuA4 histone acetyltransferase complex [GO:0035267]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; Piccolo NuA4 histone acetyltransferase complex [GO:0032777]; Swr1 complex [GO:0000812] histone H4K12 acetyltransferase activity [GO:0043997]; histone H4K16 acetyltransferase activity [GO:0046972]; histone H4K5 acetyltransferase activity [GO:0043995]; histone H4K8 acetyltransferase activity [GO:0043996]; metal ion binding [GO:0046872]; methylated histone binding [GO:0035064] 0.55091 0.5643 LYLEDYLEMIEQLPMDLRDR 0 0 9.15697 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0358 0 0 0 0 0 0 0 0 0 0 Q9NXS2 QPCTL_HUMAN Glutaminyl-peptide cyclotransferase-like protein (EC 2.3.2.5) (Golgi-resident glutaminyl-peptide cyclotransferase) (isoQC) (gQC) QPCTL Homo sapiens (Human) "peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase [GO:0017186]" Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020] glutaminyl-peptide cyclotransferase activity [GO:0016603]; zinc ion binding [GO:0008270] 0.93258 -1.276 TPGSPGNLQVRKFLEATLR 0 0 0 0 0 0 0 13.1461 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NXS3 KLH28_HUMAN Kelch-like protein 28 (BTB/POZ domain-containing protein 5) KLHL28 BTBD5 Homo sapiens (Human) 0.86751 0.070769 QHHELCDIILR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.82983 0 0 0 0 0 0 0 0 0 0 Q9NXZ1 SAGE1_HUMAN Sarcoma antigen 1 (Cancer/testis antigen 14) (CT14) SAGE1 SAGE Homo sapiens (Human) snRNA 3'-end processing [GO:0034472] integrator complex [GO:0032039]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654] 0.88906 -0.45249 DLYATVTHNVCEQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.7281 0 0 9.48565 10.4298 0 0 0 9.45847 0 0 0 Q9NXZ2 DDX43_HUMAN Probable ATP-dependent RNA helicase DDX43 (EC 3.6.4.13) (Cancer/testis antigen 13) (CT13) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen) DDX43 HAGE Homo sapiens (Human) ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.93985 -1.307 ALENFKTGK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.96967 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NY15 STAB1_HUMAN "Stabilin-1 (Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1) (FEEL-1) (MS-1 antigen)" STAB1 FEEL1 KIAA0246 Homo sapiens (Human) cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; defense response to bacterium [GO:0042742]; inflammatory response [GO:0006954]; negative regulation of angiogenesis [GO:0016525]; receptor-mediated endocytosis [GO:0006898] endocytic vesicle membrane [GO:0030666]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; hyaluronic acid binding [GO:0005540]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor activity [GO:0005041]; protein-disulfide reductase activity [GO:0015035]; scavenger receptor activity [GO:0005044] 0.87334 0.025946 AFWLQPRTLPNLVR 11.972 0 0 0 0 0 11.7934 0 0 0 0 10.8051 0 0 0 14.9726 0 0 0 0 0 0 0 0 0 0 0 Q9NY25 CLC5A_HUMAN C-type lectin domain family 5 member A (C-type lectin superfamily member 5) (Myeloid DAP12-associating lectin 1) (MDL-1) CLEC5A CLECSF5 MDL1 Homo sapiens (Human) cellular defense response [GO:0006968]; innate immune response [GO:0045087]; myeloid cell differentiation [GO:0030099]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid cell apoptotic process [GO:0033033]; osteoblast development [GO:0002076]; positive regulation of cytokine production [GO:0001819]; signal transduction [GO:0007165] cell surface [GO:0009986]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821] carbohydrate binding [GO:0030246]; virus receptor activity [GO:0001618] 0.80945 0.22595 SYGTVCPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.87144 0 0 0 0 0 0 0 Q9NY27 PP4R2_HUMAN Serine/threonine-protein phosphatase 4 regulatory subunit 2 PPP4R2 SBBI57 Homo sapiens (Human) mRNA processing [GO:0006397]; protein modification process [GO:0036211]; regulation of double-strand break repair [GO:2000779]; regulation of double-strand break repair via homologous recombination [GO:0010569]; RNA splicing [GO:0008380] centrosome [GO:0005813]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein phosphatase 4 complex [GO:0030289] protein phosphatase regulator activity [GO:0019888]; protein-macromolecule adaptor activity [GO:0030674] 0.96385 -2.4375 FDKEGEVR 0 0 11.2231 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NY28 GALT8_HUMAN Probable polypeptide N-acetylgalactosaminyltransferase 8 (EC 2.4.1.41) (Polypeptide GalNAc transferase 8) (GalNAc-T8) (pp-GaNTase 8) (Protein-UDP acetylgalactosaminyltransferase 8) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 8) GALNT8 Homo sapiens (Human) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139] carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; polypeptide N-acetylgalactosaminyltransferase activity [GO:0004653] 0.962 -2.4528 KHKTQMK 0 0 0 10.1076 0 0 0 0 0 0 0 0 0 10.9428 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NY30 BTG4_HUMAN Protein BTG4 (BTG family member 4) (Protein PC3b) BTG4 PC3B Homo sapiens (Human) negative regulation of cell population proliferation [GO:0008285]; negative regulation of mitotic cell cycle [GO:0045930]; neuron differentiation [GO:0030182]; regulation of cell cycle [GO:0051726] cytoplasm [GO:0005737]; nucleus [GO:0005634] 0.96294 -2.1267 GQAFRCIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.3415 0 0 0 0 0 Q9NY33 DPP3_HUMAN Dipeptidyl peptidase 3 (EC 3.4.14.4) (Dipeptidyl aminopeptidase III) (Dipeptidyl arylamidase III) (Dipeptidyl peptidase III) (DPP III) (Enkephalinase B) DPP3 Homo sapiens (Human) protein catabolic process [GO:0030163]; proteolysis [GO:0006508] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062] aminopeptidase activity [GO:0004177]; dipeptidyl-peptidase activity [GO:0008239]; metalloexopeptidase activity [GO:0008235]; zinc ion binding [GO:0008270] 0.33547 0.77513 GDYAPILQK 0 0 0 0 0 0 0 0 0 0 0 10.015 0 0 0 11.6375 10.6969 0 0 0 0 0 0 0 0 0 0 Q9NY37 ASIC5_HUMAN Acid-sensing ion channel 5 (ASIC5) (Amiloride-sensitive cation channel 5) (Human intestine Na(+) channel) (HINaC) ASIC5 ACCN5 HINAC Homo sapiens (Human) sodium ion transmembrane transport [GO:0035725] plasma membrane [GO:0005886] ligand-gated sodium channel activity [GO:0015280]; proton channel activity [GO:0015252] 0.73701 0.3265 IEINYSDLNYK 0 0 10.0391 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NY43 BARH2_HUMAN BarH-like 2 homeobox protein BARHL2 Homo sapiens (Human) amacrine cell differentiation [GO:0035881]; cell fate determination [GO:0001709]; neuron migration [GO:0001764]; positive regulation of translation [GO:0045727]; regulation of axon extension [GO:0030516]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.87155 0.048619 TAFSDHQLNQLER 0 0 0 0 0 9.86612 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NY46 SCN3A_HUMAN Sodium channel protein type 3 subunit alpha (Sodium channel protein brain III subunit alpha) (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subtype III) (Voltage-gated sodium channel subunit alpha Nav1.3) SCN3A KIAA1356 NAC3 Homo sapiens (Human) behavioral response to pain [GO:0048266]; calcium ion import across plasma membrane [GO:0098703]; regulation of monoatomic ion transmembrane transport [GO:0034765]; sodium ion transport [GO:0006814] sarcoplasm [GO:0016528]; voltage-gated calcium channel complex [GO:0005891]; voltage-gated sodium channel complex [GO:0001518] high voltage-gated calcium channel activity [GO:0008331]; voltage-gated sodium channel activity [GO:0005248] 0.96428 -2.2757 GERDSFPK 0 0 0 0 0 0 0 0 9.92441 0 9.00447 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NY47 CA2D2_HUMAN Voltage-dependent calcium channel subunit alpha-2/delta-2 (Voltage-gated calcium channel subunit alpha-2/delta-2) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-2; Voltage-dependent calcium channel subunit delta-2] CACNA2D2 KIAA0558 Homo sapiens (Human) regulation of monoatomic ion transmembrane transport [GO:0034765] plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891] metal ion binding [GO:0046872]; voltage-gated calcium channel activity [GO:0005245] 0.61227 0.4191 IFGGVQQLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.05452 0 0 0 10.5235 9.54353 0 10.3874 0 0 Q9NY57 ST32B_HUMAN Serine/threonine-protein kinase 32B (EC 2.7.11.1) (Yet another novel kinase 2) STK32B YANK2 UNQ3003/PRO9744 Homo sapiens (Human) intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.92724 -1.204 AIGKGSFGK 0 0 0 0 0 0 8.57856 0 0 0 0 0 0 0 0 0 13.0554 0 0 0 0 0 0 0 0 0 0 Q9NY64 GTR8_HUMAN "Solute carrier family 2, facilitated glucose transporter member 8 (Glucose transporter type 8) (GLUT-8) (Glucose transporter type X1)" SLC2A8 GLUT8 GLUTX1 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; dehydroascorbic acid transport [GO:0070837]; fructose transmembrane transport [GO:0015755]; glucose transmembrane transport [GO:1904659]; hexose transmembrane transport [GO:0008645]; insulin receptor signaling pathway [GO:0008286]; male meiosis I [GO:0007141]; response to hypoxia [GO:0001666] clathrin-coated endocytic vesicle membrane [GO:0030669]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; synaptic vesicle [GO:0008021] D-glucose transmembrane transporter activity [GO:0055056]; dehydroascorbic acid transmembrane transporter activity [GO:0033300]; fructose transmembrane transporter activity [GO:0005353]; glucose binding [GO:0005536]; glucose transmembrane transporter activity [GO:0005355] 0.88241 -0.019664 FLLTQHRR 0 0 0 0 0 0 0 0 0 0 10.0756 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2635 0 Q9NY72 SCN3B_HUMAN Sodium channel subunit beta-3 SCN3B KIAA1158 Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; cardiac muscle cell action potential involved in contraction [GO:0086002]; cardiac muscle contraction [GO:0060048]; membrane depolarization [GO:0051899]; membrane depolarization during action potential [GO:0086010]; membrane depolarization during cardiac muscle cell action potential [GO:0086012]; nervous system development [GO:0007399]; positive regulation of heart rate [GO:0010460]; positive regulation of sodium ion transport [GO:0010765]; protein localization to plasma membrane [GO:0072659]; regulation of atrial cardiac muscle cell membrane depolarization [GO:0060371]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of sodium ion transmembrane transporter activity [GO:2000649]; regulation of ventricular cardiac muscle cell membrane depolarization [GO:0060373]; SA node cell action potential [GO:0086015]; sensory perception of pain [GO:0019233]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]; ventricular cardiac muscle cell action potential [GO:0086005] membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated sodium channel complex [GO:0001518]; Z disc [GO:0030018] sodium channel inhibitor activity [GO:0019871]; sodium channel regulator activity [GO:0017080]; transmembrane transporter binding [GO:0044325]; voltage-gated monoatomic ion channel activity [GO:0005244]; voltage-gated sodium channel activity involved in cardiac muscle cell action potential [GO:0086006] 0.951 -1.3838 DFLIYEYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.83592 0 0 0 0 0 0 0 0 0 0 0 Q9NY93 DDX56_HUMAN Probable ATP-dependent RNA helicase DDX56 (EC 3.6.4.13) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD box protein 21) (DEAD box protein 56) DDX56 DDX21 NOH61 Homo sapiens (Human) defense response to virus [GO:0051607]; modulation by host of viral RNA genome replication [GO:0044830]; negative regulation of type I interferon production [GO:0032480]; positive regulation of neuron projection development [GO:0010976]; rRNA processing [GO:0006364] cytosol [GO:0005829]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; protein sequestering activity [GO:0140311]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA stem-loop binding [GO:0035613] 0.88165 -0.30141 LKTYFEDNPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.58192 0 0 0 0 0 0 0 0 0 0 0 0 Q9NYA3 GOG6A_HUMAN Golgin subfamily A member 6A (Golgin linked to PML) (Golgin-like protein) GOLGA6A GLP GOLGA6 Homo sapiens (Human) Golgi organization [GO:0007030] cis-Golgi network [GO:0005801]; Golgi cis cisterna [GO:0000137]; Golgi cisterna membrane [GO:0032580] 0.97015 -3.2476 LAQKEEEMK 0 0 0 0 0 0 0 0 0 0 9.85158 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NYA4 MTMR4_HUMAN Myotubularin-related protein 4 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 2) (FYVE-DSP2) (Zinc finger FYVE domain-containing protein 11) MTMR4 KIAA0647 ZFYVE11 Homo sapiens (Human) negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; phosphatidylinositol biosynthetic process [GO:0006661]; protein dephosphorylation [GO:0006470]; regulation of autophagy [GO:0010506]; regulation of phosphatidylinositol dephosphorylation [GO:0060304] cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; extracellular space [GO:0005615] "metal ion binding [GO:0046872]; phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity [GO:0052629]; phosphatidylinositol-3-phosphate phosphatase activity [GO:0004438]; protein phosphatase binding [GO:0019903]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine phosphatase activity [GO:0004725]" 0.75984 0.29417 AAVLVANTVDR 0 0 0 0 9.29928 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NYB5 SO1C1_HUMAN Solute carrier organic anion transporter family member 1C1 (Organic anion transporter 1C1) (OATP1C1) (Organic anion transporter F) (OATP-F) (Organic anion transporter polypeptide-related protein 5) (OAT-RP-5) (OATP-RP5) (Organic anion-transporting polypeptide 14) (OATP-14) (Solute carrier family 21 member 14) (Thyroxine transporter) SLCO1C1 OATP14 OATP1C1 OATPF SLC21A14 Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; monoatomic ion transport [GO:0006811]; positive regulation of thyroid hormone generation [GO:2000611]; sodium-independent organic anion transport [GO:0043252]; thyroid hormone transport [GO:0070327]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104] basolateral plasma membrane [GO:0016323]; plasma membrane [GO:0005886] bile acid transmembrane transporter activity [GO:0015125]; organic anion transmembrane transporter activity [GO:0008514]; sodium-independent organic anion transmembrane transporter activity [GO:0015347]; thyroid hormone transmembrane transporter activity [GO:0015349] 0.92165 -1.0943 ALAEGYLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.74819 0 Q9NYB9 ABI2_HUMAN Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1) ABI2 ARGBPIA Homo sapiens (Human) actin polymerization or depolymerization [GO:0008154]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; lens fiber cell morphogenesis [GO:0070309]; nervous system development [GO:0007399]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; positive regulation of lamellipodium assembly [GO:0010592]; Rac protein signal transduction [GO:0016601]; regulation of dendritic spine morphogenesis [GO:0061001]; zonula adherens assembly [GO:0045186] adherens junction [GO:0005912]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; filopodium tip [GO:0032433]; lamellipodium [GO:0030027]; nucleus [GO:0005634]; SCAR complex [GO:0031209] cytoskeletal anchor activity [GO:0008093]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; proline-rich region binding [GO:0070064]; SH3 domain binding [GO:0017124]; signaling adaptor activity [GO:0035591]; ubiquitin protein ligase binding [GO:0031625] 0.84064 0.18094 TYSSSGSSGGSHPSSR 0 0 0 0 0 0 0 0 0 0 9.4131 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NYC9 DYH9_HUMAN Dynein axonemal heavy chain 9 (Axonemal beta dynein heavy chain 9) (Ciliary dynein heavy chain 9) DNAH9 DNAH17L DNEL1 KIAA0357 Homo sapiens (Human) cell projection organization [GO:0030030]; cerebrospinal fluid circulation [GO:0090660]; cilium movement [GO:0003341]; establishment of localization in cell [GO:0051649]; mucociliary clearance [GO:0120197] 9+2 motile cilium [GO:0097729]; axoneme [GO:0005930]; distal portion of axoneme [GO:0120135]; dynein complex [GO:0030286]; extracellular region [GO:0005576]; microtubule [GO:0005874]; motile cilium [GO:0031514]; outer dynein arm [GO:0036157] ATP binding [GO:0005524]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; minus-end-directed microtubule motor activity [GO:0008569] 0.96908 -6.8732 AKIAHLNENLAKLTAR 12.962 0 0 0 0 11.6964 0 16.2626 0 8.96702 10.4921 9.55815 0 0 0 0 9.84378 0 0 12.8442 0 9.42074 0 9.96054 9.36418 0 11.5046 Q9NYF0 DACT1_HUMAN Dapper homolog 1 (hDPR1) (Dapper antagonist of catenin 1) (Hepatocellular carcinoma novel gene 3 protein) DACT1 DPR1 HNG3 Homo sapiens (Human) "embryonic hindgut morphogenesis [GO:0048619]; negative regulation of beta-catenin-TCF complex assembly [GO:1904864]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of JNK cascade [GO:0046329]; negative regulation of protein binding [GO:0032091]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of Wnt signaling pathway [GO:0030178]; neural tube development [GO:0021915]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of protein binding [GO:0032092]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of protein stability [GO:0031647]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; synapse [GO:0045202] beta-catenin binding [GO:0008013]; delta-catenin binding [GO:0070097]; histone deacetylase binding [GO:0042826]; protein kinase A binding [GO:0051018]; protein kinase C binding [GO:0005080]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629] 0.9695 -3.5847 AGSRAHGHGR 0 0 0 0 0 0 0 0 0 0 0 11.011 0 0 0 0 0 0 0 9.38974 0 0 0 0 0 0 0 Q9NYF3 FA53C_HUMAN Protein FAM53C FAM53C C5orf6 Homo sapiens (Human) protein import into nucleus [GO:0006606] nucleus [GO:0005634] 0.86306 0.090018 WQPVWRPAPSK 10.1563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NYF5 FA13B_HUMAN Protein FAM13B (GAP-like protein N61) FAM13B C5orf5 FAM13B1 Homo sapiens (Human) regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] cytosol [GO:0005829] GTPase activator activity [GO:0005096] 0.64234 0.39646 EQEIVSR 0 0 0 0 0 0 0 0 0 0 0 0 0 8.29733 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NYF8 BCLF1_HUMAN Bcl-2-associated transcription factor 1 (Btf) (BCLAF1 and THRAP3 family member 1) BCLAF1 BTF KIAA0164 Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to leukemia inhibitory factor [GO:1990830]; DNA damage response [GO:0006974]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-templated transcription initiation [GO:2000144]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription in response to stress [GO:0043620] cytoplasm [GO:0005737]; mediator complex [GO:0016592]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; RNA binding [GO:0003723]; transcription coregulator activity [GO:0003712] 0.95187 -1.3932 AEGEWEDQEALDYFSDK 10.121 0 0 11.6954 12.2156 12.1457 0 0 11.1803 0 0 9.14315 0 0 8.92704 0 0 0 0 0 9.64357 0 0 0 0 0 11.1142 Q9NYG8 KCNK4_HUMAN Potassium channel subfamily K member 4 (TWIK-related arachidonic acid-stimulated potassium channel protein) (TRAAK) (Two pore potassium channel KT4.1) (Two pore K(+) channel KT4.1) KCNK4 TRAAK Homo sapiens (Human) cellular response to alkaline pH [GO:0071469]; cellular response to fatty acid [GO:0071398]; cellular response to mechanical stimulus [GO:0071260]; cellular response to temperature stimulus [GO:0071502]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; memory [GO:0007613]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of monoatomic ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]; sensory perception of temperature stimulus [GO:0050951]; stabilization of membrane potential [GO:0030322] plasma membrane [GO:0005886]; potassium channel complex [GO:0034705] identical protein binding [GO:0042802]; mechanosensitived potassium channel activity [GO:0098782]; potassium channel activity [GO:0005267]; potassium ion leak channel activity [GO:0022841]; temperature-gated cation channel activity [GO:0097604]; voltage-gated monoatomic ion channel activity [GO:0005244] 0.91376 -0.79829 RRPNPPR 10.3995 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NYH9 UTP6_HUMAN U3 small nucleolar RNA-associated protein 6 homolog (Hepatocellular carcinoma-associated antigen 66) (Multiple hat domains protein) UTP6 C17orf40 HCA66 MHAT Homo sapiens (Human) "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosomal small subunit biogenesis [GO:0042274]" chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; Pwp2p-containing subcomplex of 90S preribosome [GO:0034388]; small-subunit processome [GO:0032040] snoRNA binding [GO:0030515] 0.91775 -0.86635 EYYERALR 0 0 0 0 0 0 0 0 0 8.80774 9.43931 8.79831 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NYI0 PSD3_HUMAN PH and SEC7 domain-containing protein 3 (Epididymis tissue protein Li 20mP) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 D) (Exchange factor for ARF6 D) (Hepatocellular carcinoma-associated antigen 67) (Pleckstrin homology and SEC7 domain-containing protein 3) PSD3 EFA6D EFA6R HCA67 KIAA0942 Homo sapiens (Human) regulation of ARF protein signal transduction [GO:0032012] postsynaptic density [GO:0014069]; ruffle membrane [GO:0032587] guanyl-nucleotide exchange factor activity [GO:0005085] 0.9619 -2.6067 ANGTHPK 0 0 0 0 0 0 0 0 0 9.60108 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7964 0 9.86521 0 Q9NYJ8 TAB2_HUMAN TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 2) (TAK1-binding protein 2) (TAB-2) (TGF-beta-activated kinase 1-binding protein 2) TAB2 KIAA0733 MAP3K7IP2 Homo sapiens (Human) heart development [GO:0007507]; inflammatory response [GO:0006954]; negative regulation of autophagy [GO:0010507]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein kinase activity [GO:0045860]; response to lipopolysaccharide [GO:0032496] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; lysosomal membrane [GO:0005765]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] K63-linked polyubiquitin modification-dependent protein binding [GO:0070530]; molecular adaptor activity [GO:0060090]; protein serine/threonine kinase activator activity [GO:0043539]; ubiquitin binding [GO:0043130]; zinc ion binding [GO:0008270] 0.86357 0.080102 NQPTLFISTNSGASAASR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3144 0 0 0 0 0 0 0 0 0 Q9NYK1 TLR7_HUMAN Toll-like receptor 7 TLR7 UNQ248/PRO285 Homo sapiens (Human) cellular response to mechanical stimulus [GO:0071260]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; I-kappaB phosphorylation [GO:0007252]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; JNK cascade [GO:0007254]; positive regulation of chemokine production [GO:0032722]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type II interferon production [GO:0032729]; regulation of protein phosphorylation [GO:0001932]; response to cGMP [GO:0070305]; toll-like receptor 7 signaling pathway [GO:0034154]; toll-like receptor signaling pathway [GO:0002224] cytoplasm [GO:0005737]; early phagosome [GO:0032009]; endolysosome membrane [GO:0036020]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi membrane [GO:0000139]; lysosome [GO:0005764]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] double-stranded RNA binding [GO:0003725]; pattern recognition receptor activity [GO:0038187]; single-stranded RNA binding [GO:0003727]; siRNA binding [GO:0035197] 0.43008 0.6606 TLPCDVTLDVPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2432 9.14588 0 10.799 0 0 0 Q9NYK5 RM39_HUMAN "Large ribosomal subunit protein mL39 (39S ribosomal protein L39, mitochondrial) (L39mt) (MRP-L39) (39S ribosomal protein L5, mitochondrial) (L5mt) (MRP-L5)" MRPL39 C21orf92 MRPL5 RPML5 MSTP003 PRED22 Homo sapiens (Human) mitochondrial translation [GO:0032543] mitochondrial inner membrane [GO:0005743]; mitochondrial large ribosomal subunit [GO:0005762]; mitochondrial ribosome [GO:0005761]; mitochondrion [GO:0005739] nucleotide binding [GO:0000166]; RNA binding [GO:0003723] 0.92409 -1.0486 FQGVSLPVHLRAHFTIWDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9892 0 0 Q9NYL2 M3K20_HUMAN Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical cancer suppressor gene 4 protein) (HCCS-4) (Leucine zipper- and sterile alpha motif-containing kinase) (MLK-like mitogen-activated protein triple kinase) (Mitogen-activated protein kinase kinase kinase MLT) (Mixed lineage kinase 7) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) MAP3K20 MLK7 MLTK ZAK HCCS4 Homo sapiens (Human) cell death [GO:0008219]; cell differentiation [GO:0030154]; cellular response to gamma radiation [GO:0071480]; cellular response to UV-B [GO:0071493]; chromosome segregation [GO:0007059]; cytoskeleton organization [GO:0007010]; DNA damage checkpoint signaling [GO:0000077]; embryonic digit morphogenesis [GO:0042733]; GCN2-mediated signaling [GO:0140469]; JNK cascade [GO:0007254]; limb development [GO:0060173]; negative regulation of stress-activated protein kinase signaling cascade [GO:0070303]; negative regulation of translation in response to endoplasmic reticulum stress [GO:1902010]; p38MAPK cascade [GO:0038066]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic process [GO:0043065]; positive regulation of mitotic DNA damage checkpoint [GO:1904291]; positive regulation of programmed cell death [GO:0043068]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; pyroptosis [GO:0070269]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; stress-activated MAPK cascade [GO:0051403]; stress-activated protein kinase signaling cascade [GO:0031098] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] ATP binding [GO:0005524]; JUN kinase kinase kinase activity [GO:0004706]; magnesium ion binding [GO:0000287]; MAP kinase kinase kinase activity [GO:0004709]; protein kinase activator activity [GO:0030295]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activator activity [GO:0043539]; protein serine/threonine kinase activity [GO:0004674]; ribosome binding [GO:0043022]; RNA binding [GO:0003723]; small ribosomal subunit rRNA binding [GO:0070181]; stalled ribosome sensor activity [GO:0170011]; translation regulator activity [GO:0045182] 0.89037 -0.46999 ASEEDSK 0 0 9.47107 0 9.981 0 0 0 0 8.73569 0 0 0 10.7511 0 11.4789 11.5734 11.3538 0 0 0 0 0 0 0 0 0 Q9NYL5 CP39A_HUMAN 24-hydroxycholesterol 7-alpha-hydroxylase (EC 1.14.14.26) (Cytochrome P450 39A1) (hCYP39A1) (Oxysterol 7-alpha-hydroxylase) CYP39A1 Homo sapiens (Human) bile acid biosynthetic process [GO:0006699]; cholesterol catabolic process [GO:0006707]; cholesterol homeostasis [GO:0042632]; digestion [GO:0007586]; sterol metabolic process [GO:0016125] endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231] 24-hydroxycholesterol 7alpha-hydroxylase activity [GO:0033782]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxysterol 7-alpha-hydroxylase activity [GO:0008396]; steroid 7-alpha-hydroxylase activity [GO:0008387] 0.96116 -2.5603 SLFSTNK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.13994 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NYL9 TMOD3_HUMAN Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod) TMOD3 Homo sapiens (Human) erythrocyte development [GO:0048821]; mitotic cell cycle phase transition [GO:0044772]; muscle contraction [GO:0006936]; myofibril assembly [GO:0030239]; pointed-end actin filament capping [GO:0051694]; positive regulation of mitotic cell cycle phase transition [GO:1901992] adherens junction [GO:0005912]; striated muscle thin filament [GO:0005865] actin binding [GO:0003779]; cadherin binding involved in cell-cell adhesion [GO:0098641]; tropomyosin binding [GO:0005523] 0.96989 -3.3032 DREDYVPYTGEK 0 0 0 0 0 9.26388 0 0 0 9.56405 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NYP3 DONS_HUMAN Protein downstream neighbor of Son (B17) DONSON C21orf60 Homo sapiens (Human) DNA damage checkpoint signaling [GO:0000077]; DNA replication [GO:0006260]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; nuclear DNA replication [GO:0033260]; replication fork processing [GO:0031297] nucleus [GO:0005634]; replication fork [GO:0005657]; replisome [GO:0030894] 0.56266 0.50979 KPPEVVR 0 0 0 0 0 0 0 0 0 0 15.3902 0 0 0 0 0 0 0 0 0 0 9.43723 0 9.8775 9.57954 0 9.71689 Q9NYP8 CU062_HUMAN Uncharacterized protein C21orf62 (B37) C21orf62 C21orf120 Homo sapiens (Human) 0.87579 0.0018365 DCDYSLANLMCNCK 0 0 0 0 9.74786 0 0 0 10.3571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NYP9 MS18A_HUMAN Protein Mis18-alpha (FAPP1-associated protein 1) MIS18A C21orf45 C21orf46 FASP1 Homo sapiens (Human) cell division [GO:0051301]; CENP-A containing chromatin assembly [GO:0034080]; chromosome segregation [GO:0007059]; regulation of DNA methylation [GO:0044030] "chromatin [GO:0000785]; chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]" identical protein binding [GO:0042802]; metal ion binding [GO:0046872] 0.80557 0.23648 ELFNLESR 0 0 0 0 0 0 0 0 0 0 0 0 11.9286 0 0 0 0 0 0 0 0 0 10.2596 10.0204 0 0 0 Q9NYQ3 HAOX2_HUMAN "2-Hydroxyacid oxidase 2 (HAOX2) (EC 1.1.3.15) ((S)-2-hydroxy-acid oxidase, peroxisomal) (Cell growth-inhibiting gene 16 protein) (Long chain alpha-hydroxy acid oxidase) (Long-chain L-2-hydroxy acid oxidase)" HAO2 HAOX2 GIG16 Homo sapiens (Human) fatty acid alpha-oxidation [GO:0001561]; fatty acid oxidation [GO:0019395] cytosol [GO:0005829]; peroxisomal matrix [GO:0005782] (S)-2-hydroxy-acid oxidase activity [GO:0003973]; FMN binding [GO:0010181] 0.84027 0.17989 DDNIAAFK 0 0 0 0 0 0 0 0 0 0 11.8675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NYQ6 CELR1_HUMAN Cadherin EGF LAG seven-pass G-type receptor 1 (Cadherin family member 9) (Flamingo homolog 2) (hFmi2) CELSR1 CDHF9 FMI2 Homo sapiens (Human) "apical protein localization [GO:0045176]; cell-cell adhesion [GO:0098609]; central nervous system development [GO:0007417]; establishment of body hair planar orientation [GO:0048105]; establishment of planar polarity [GO:0001736]; establishment of planar polarity of embryonic epithelium [GO:0042249]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lateral sprouting involved in lung morphogenesis [GO:0060490]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060488]; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060489]; protein localization involved in establishment of planar polarity [GO:0090251]; regulation of actin cytoskeleton organization [GO:0032956]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; G protein-coupled receptor activity [GO:0004930] 0.9555 -1.5982 LLAQDTCLPCDCFPHGSHSR 0 0 0 0 0 0 0 0 0 0 12.2208 0 0 0 0 0 0 0 0 0 9.62511 0 0 0 0 0 0 Q9NYQ7 CELR3_HUMAN Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2) CELSR3 CDHF11 EGFL1 FMI1 KIAA0812 MEGF2 Homo sapiens (Human) "cell-cell adhesion [GO:0098609]; G protein-coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" membrane [GO:0016020]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; G protein-coupled receptor activity [GO:0004930] 0.96824 -8.861 ATTSGAERTAPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.5112 0 9.60242 10.4724 9.88606 9.17732 10.3884 0 12.9534 Q9NYQ8 FAT2_HUMAN Protocadherin Fat 2 (hFat2) (Cadherin family member 8) (Multiple epidermal growth factor-like domains protein 1) (Multiple EGF-like domains protein 1) FAT2 CDHF8 KIAA0811 MEGF1 Homo sapiens (Human) cell-substrate adhesion [GO:0031589]; epithelial cell migration [GO:0010631]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] adherens junction [GO:0005912]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.88369 -0.29903 ATDGGGR 0 0 0 0 0 0 0 0 0 0 0 0 10.0355 11.0604 9.96737 10.1481 10.1804 10.9875 0 0 0 0 0 0 0 0 0 Q9NYR8 RDH8_HUMAN Retinol dehydrogenase 8 (EC 1.1.1.300) (Photoreceptor outer segment all-trans retinol dehydrogenase) (Short chain dehydrogenase/reductase family 28C member 2) RDH8 PRRDH SDR28C2 Homo sapiens (Human) estrogen biosynthetic process [GO:0006703]; response to stimulus [GO:0050896]; retinol metabolic process [GO:0042572]; steroid biosynthetic process [GO:0006694]; visual perception [GO:0007601] cytosol [GO:0005829]; plasma membrane [GO:0005886] estradiol 17-beta-dehydrogenase [NAD(P)] activity [GO:0004303]; NAD-retinol dehydrogenase activity [GO:0004745]; NADP-retinol dehydrogenase activity [GO:0052650] 0.78459 0.25581 AVLPGMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.3789 0 0 0 0 Q9NYT0 PLEK2_HUMAN Pleckstrin-2 PLEK2 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; intracellular signal transduction [GO:0035556]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; lamellipodium membrane [GO:0031258]; plasma membrane [GO:0005886] "phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]" 0.94816 -1.3645 AEWIEAIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.43208 0 Q9NYT6 ZN226_HUMAN Zinc finger protein 226 ZNF226 Homo sapiens (Human) nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.95314 -1.485 SLTCVERGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4054 0 Q9NYU1 UGGG2_HUMAN UDP-glucose:glycoprotein glucosyltransferase 2 (UGT2) (hUGT2) (EC 2.4.1.-) (UDP--Glc:glycoprotein glucosyltransferase 2) (UDP-glucose ceramide glucosyltransferase-like 1) UGGT2 UGCGL2 UGT2 Homo sapiens (Human) endoplasmic reticulum mannose trimming [GO:1904380]; ER-associated misfolded protein catabolic process [GO:0071712]; protein N-linked glycosylation via asparagine [GO:0018279] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum quality control compartment [GO:0044322]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; protein-containing complex [GO:0032991] UDP-glucose:glycoprotein glucosyltransferase activity [GO:0003980]; unfolded protein binding [GO:0051082] 0.97 -5.3738 ASRYDVTFLR 10.3898 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.36072 9.67172 0 0 8.62092 0 0 0 Q9NYU2 UGGG1_HUMAN UDP-glucose:glycoprotein glucosyltransferase 1 (UGT1) (hUGT1) (EC 2.4.1.-) (UDP--Glc:glycoprotein glucosyltransferase) (UDP-glucose ceramide glucosyltransferase-like 1) UGGT1 GT UGCGL1 UGGT UGT1 UGTR Homo sapiens (Human) 'de novo' post-translational protein folding [GO:0051084]; endoplasmic reticulum mannose trimming [GO:1904380]; ER-associated misfolded protein catabolic process [GO:0071712]; protein N-linked glycosylation via asparagine [GO:0018279] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum quality control compartment [GO:0044322]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; protein-containing complex [GO:0032991] UDP-glucose:glycoprotein glucosyltransferase activity [GO:0003980]; unfolded protein binding [GO:0051082] 0.97004 -3.231 AITTSLTTK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.53 0 0 8.44692 0 0 0 0 0 0 0 0 13.002 0 Q9NYV4 CDK12_HUMAN "Cyclin-dependent kinase 12 (EC 2.7.11.22) (EC 2.7.11.23) (Cdc2-related kinase, arginine/serine-rich) (CrkRS) (Cell division cycle 2-related protein kinase 7) (CDC2-related protein kinase 7) (Cell division protein kinase 12) (hCDK12)" CDK12 CRK7 CRKRS KIAA0904 Homo sapiens (Human) mRNA processing [GO:0006397]; negative regulation of stem cell differentiation [GO:2000737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; protein autophosphorylation [GO:0046777]; regulation of MAP kinase activity [GO:0043405]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]; transcription by RNA polymerase II [GO:0006366] cyclin K-CDK12 complex [GO:0002944]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; nuclear cyclin-dependent protein kinase holoenzyme complex [GO:0019908]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine kinase activity [GO:0106310]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353] 0.96933 -6.1887 ELKSGHKDR 0 0 0 0 0 10.0922 10.1553 9.80819 0 0 9.57599 0 11.9286 0 0 0 10.4069 0 0 0 0 0 0 0 0 0 9.14326 Q9NYV8 T2R14_HUMAN Taste receptor type 2 member 14 (T2R14) (Taste receptor family B member 1) (TRB1) TAS2R14 Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; G protein-coupled receptor signaling pathway [GO:0007186] membrane [GO:0016020]; plasma membrane [GO:0005886] bitter taste receptor activity [GO:0033038]; G protein-coupled receptor activity [GO:0004930]; taste receptor activity [GO:0008527] 0.94343 -1.3374 ISGDASTKAHR 0 0 0 0 0 0 0 0 0 0 0 0 9.16865 0 0 0 0 0 0 0 0 0 0 0 0 10.464 0 Q9NYW2 TA2R8_HUMAN Taste receptor type 2 member 8 (T2R8) (Taste receptor family B member 5) (TRB5) TAS2R8 Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580] membrane [GO:0016020]; plasma membrane [GO:0005886] bitter taste receptor activity [GO:0033038]; G protein-coupled receptor activity [GO:0004930]; taste receptor activity [GO:0008527] 0.89903 -0.57503 DPSTEVHVRAIK 0 0 0 0 0 0 0 0 0 11.8382 0 11.8336 0 10.0794 10.3139 11.1648 10.54 10.4614 0 0 10.0331 0 0 0 0 0 10.1787 Q9NYW3 TA2R7_HUMAN Taste receptor type 2 member 7 (T2R7) (Taste receptor family B member 4) (TRB4) TAS2R7 Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580] membrane [GO:0016020]; plasma membrane [GO:0005886] bitter taste receptor activity [GO:0033038]; G protein-coupled receptor activity [GO:0004930]; taste receptor activity [GO:0008527] 0.88993 -0.45597 DPSTEAHVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1055 9.88868 0 0 0 Q9NYW5 TA2R4_HUMAN Taste receptor type 2 member 4 (T2R4) TAS2R4 Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; respiratory gaseous exchange by respiratory system [GO:0007585] ciliary membrane [GO:0060170]; membrane [GO:0016020]; plasma membrane [GO:0005886] bitter taste receptor activity [GO:0033038]; G protein-coupled receptor activity [GO:0004930]; taste receptor activity [GO:0008527] 0.95546 -1.584 TWVKSHR 0 0 0 0 10.331 10.3622 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NYW7 TA2R1_HUMAN Taste receptor type 2 member 1 (T2R1) (Taste receptor family B member 7) (TRB7) TAS2R1 Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580] membrane [GO:0016020]; plasma membrane [GO:0005886] bitter taste receptor activity [GO:0033038]; G protein-coupled receptor activity [GO:0004930]; taste receptor activity [GO:0008527] 0.6237 0.41463 NTVAGSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.988 10.1558 0 Q9NYW8 RBAK_HUMAN RB-associated KRAB zinc finger protein (RB-associated KRAB repressor) (hRBaK) (Zinc finger protein 769) RBAK ZNF769 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; zinc ion binding [GO:0008270]" 0.92348 -1.0731 HSRQAACINSK 0 0 0 0 0 0 0 0 0 0 0 9.62617 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NYY1 IL20_HUMAN Interleukin-20 (IL-20) (Cytokine Zcyto10) IL20 ZCYTO10 UNQ852/PRO1801 Homo sapiens (Human) osteoclast differentiation [GO:0030316]; positive regulation of epidermal cell differentiation [GO:0045606]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of inflammatory response [GO:0050727] extracellular region [GO:0005576]; extracellular space [GO:0005615] cytokine activity [GO:0005125]; interleukin-20 receptor binding [GO:0045517]; interleukin-22 receptor binding [GO:0045518] 0.95562 -1.5463 GSVQAKDGNIDIR 0 0 0 0 0 0 0 0 0 0 0 11.9145 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NYY3 PLK2_HUMAN Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 2) (PLK-2) (hPlk2) (Serine/threonine-protein kinase SNK) (hSNK) (Serum-inducible kinase) PLK2 SNK Homo sapiens (Human) "DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; G1/S transition of mitotic cell cycle [GO:0000082]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; mitotic spindle organization [GO:0007052]; negative regulation of angiogenesis [GO:0016525]; negative regulation of apoptotic process [GO:0043066]; negative regulation of apoptotic process in bone marrow cell [GO:0071866]; negative regulation of cellular senescence [GO:2000773]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of autophagy [GO:0010508]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein catabolic process [GO:0045732]; protein phosphorylation [GO:0006468]; Rap protein signal transduction [GO:0032486]; Ras protein signal transduction [GO:0007265]; regulation of centriole replication [GO:0046599]; regulation of synaptic plasticity [GO:0048167]" centriole [GO:0005814]; centrosome [GO:0005813]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; kinetochore [GO:0000776]; nucleus [GO:0005634]; spindle pole [GO:0000922] ATP binding [GO:0005524]; ATP-dependent protein binding [GO:0043008]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.91518 -0.78041 LTTLLMSGCSSELKNR 10.3793 11.1387 9.81954 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.77076 0 0 0 0 0 Q9NYY8 FAKD2_HUMAN "FAST kinase domain-containing protein 2, mitochondrial" FASTKD2 KIAA0971 Homo sapiens (Human) apoptotic process [GO:0006915]; mitochondrial large ribosomal subunit assembly [GO:1902775]; mitochondrial RNA processing [GO:0000963]; mitochondrial translation [GO:0032543]; positive regulation of mitochondrial translation [GO:0070131]; regulation of mitochondrial mRNA stability [GO:0044528]; RNA processing [GO:0006396] mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; ribonucleoprotein granule [GO:0035770] RNA binding [GO:0003723]; rRNA binding [GO:0019843] 0.74492 0.31941 AGSFFWNLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1932 0 0 0 0 0 0 Q9NYZ3 GTSE1_HUMAN G2 and S phase-expressed protein 1 (GTSE-1) (Protein B99 homolog) GTSE1 Homo sapiens (Human) "DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; microtubule-based process [GO:0007017]" cytoplasmic microtubule [GO:0005881]; cytosol [GO:0005829]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; nucleoplasm [GO:0005654] microtubule binding [GO:0008017] 0.9228 -1.1489 FSIGDSPDSSTPK 9.61969 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NYZ4 SIGL8_HUMAN Sialic acid-binding Ig-like lectin 8 (Siglec-8) (Sialoadhesin family member 2) (SAF-2) SIGLEC8 SAF2 Homo sapiens (Human) cell adhesion [GO:0007155]; signal transduction [GO:0007165] membrane [GO:0016020]; plasma membrane [GO:0005886] carbohydrate binding [GO:0030246]; sialic acid binding [GO:0033691]; transmembrane signaling receptor activity [GO:0004888] 0.95397 -1.5137 WSYKSQLNYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5187 0 0 0 0 0 0 0 Q9NZ01 TECR_HUMAN "Very-long-chain enoyl-CoA reductase (EC 1.3.1.93) (Synaptic glycoprotein SC2) (Trans-2,3-enoyl-CoA reductase) (TER)" TECR GPSN2 SC2 Homo sapiens (Human) fatty acid elongation [GO:0030497]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; sphingolipid metabolic process [GO:0006665]; very long-chain fatty acid biosynthetic process [GO:0042761] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nucleus [GO:0005634] oxidoreductase activity [GO:0016491]; very-long-chain enoyl-CoA reductase activity [GO:0102758]; very-long-chain-acyl-CoA dehydrogenase activity [GO:0017099] 0 3.6419 LPVGTTATLYFR 0 0 0 0 0 0 0 9.08188 12.06 0 0 0 0 0 9.30882 9.60687 9.50142 0 9.68328 0 0 0 0 0 0 0 0 Q9NZ08 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1 (EC 3.4.11.-) (ARTS-1) (Adipocyte-derived leucine aminopeptidase) (A-LAP) (Aminopeptidase PILS) (Puromycin-insensitive leucyl-specific aminopeptidase) (PILS-AP) (Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator) ERAP1 APPILS ARTS1 KIAA0525 UNQ584/PRO1154 Homo sapiens (Human) adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; fat cell differentiation [GO:0045444]; membrane protein ectodomain proteolysis [GO:0006509]; peptide catabolic process [GO:0043171]; positive regulation of angiogenesis [GO:0045766]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of innate immune response [GO:0045088]; response to bacterium [GO:0009617] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020] "aminopeptidase activity [GO:0004177]; endopeptidase activity [GO:0004175]; interleukin-1, type II receptor binding [GO:0005151]; interleukin-6 receptor binding [GO:0005138]; metalloaminopeptidase activity [GO:0070006]; metalloexopeptidase activity [GO:0008235]; peptide binding [GO:0042277]; zinc ion binding [GO:0008270]" 0.8763 0.00073383 EYLSADAFK 0 0 0 0 0 0 0 0 0 0 0 9.72577 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NZ32 ARP10_HUMAN Actin-related protein 10 (Actin-related protein 11) (hARP11) ACTR10 ACTR11 ARP10 ARP11 Homo sapiens (Human) retrograde axonal transport of mitochondrion [GO:0098958] axon cytoplasm [GO:1904115]; azurophil granule lumen [GO:0035578]; cytosol [GO:0005829]; dynactin complex [GO:0005869]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813] 0.92374 -1.0544 AGMPKPVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1233 0 0 0 0 0 0 0 0 0 10.0391 0 Q9NZ42 PEN2_HUMAN Gamma-secretase subunit PEN-2 (Presenilin enhancer protein 2) PSENEN PEN2 MDS033 Homo sapiens (Human) amyloid precursor protein catabolic process [GO:0042987]; amyloid precursor protein metabolic process [GO:0042982]; amyloid-beta formation [GO:0034205]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; positive regulation of catalytic activity [GO:0043085]; positive regulation of endopeptidase activity [GO:0010950]; protein processing [GO:0016485] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; gamma-secretase complex [GO:0070765]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; membrane [GO:0016020]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734] endopeptidase activator activity [GO:0061133]; enzyme binding [GO:0019899] 0.93981 -1.2987 VSNEEKLNLCRK 0 0 0 0 0 0 9.87557 10.0309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NZ43 USE1_HUMAN Vesicle transport protein USE1 (Putative MAPK-activating protein PM26) (USE1-like protein) (p31) USE1 USE1L MDS032 Homo sapiens (Human) "lysosomal transport [GO:0007041]; protein catabolic process [GO:0030163]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; secretion by cell [GO:0032940]" endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; SNARE complex [GO:0031201] SNAP receptor activity [GO:0005484] 0.96932 -6.1114 ERVPATKTVHLQSR 14.6172 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.92238 0 0 0 0 0 0 0 Q9NZ52 GGA3_HUMAN "ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3)" GGA3 KIAA0154 Homo sapiens (Human) endocytic recycling [GO:0032456]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi to plasma membrane transport [GO:0006893]; intracellular protein transport [GO:0006886]; negative regulation of amyloid-beta formation [GO:1902430]; positive regulation of protein catabolic process [GO:0045732]; protein catabolic process [GO:0030163]; protein destabilization [GO:0031648]; protein localization to cell surface [GO:0034394]; protein targeting to lysosome [GO:0006622]; regulation of protein stability [GO:0031647] early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; protein-containing complex [GO:0032991]; recycling endosome membrane [GO:0055038]; trans-Golgi network [GO:0005802] phosphatidylinositol binding [GO:0035091]; protein-containing complex binding [GO:0044877]; small GTPase binding [GO:0031267]; ubiquitin binding [GO:0043130] 0.95447 -1.503 IKDAYHMLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4227 0 Q9NZ56 FMN2_HUMAN Formin-2 FMN2 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell migration [GO:0016477]; cellular response to hypoxia [GO:0071456]; DNA damage response [GO:0006974]; establishment of meiotic spindle localization [GO:0051295]; formin-nucleated actin cable assembly [GO:0070649]; homologous chromosome movement towards spindle pole in meiosis I anaphase [GO:0051758]; intracellular signal transduction [GO:0035556]; intracellular transport [GO:0046907]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein catabolic process [GO:0042177]; oogenesis [GO:0048477]; polar body extrusion after meiotic divisions [GO:0040038]; positive regulation of double-strand break repair [GO:2000781]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; microvillus [GO:0005902]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; spindle [GO:0005819] actin binding [GO:0003779] 0.96342 -2.1005 FEDFQKDLRK 8.67345 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NZ63 TLS1_HUMAN Splicing factor C9orf78 (Hepatocellular carcinoma-associated antigen 59) C9orf78 HCA59 Homo sapiens (Human) "chromosome segregation [GO:0007059]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; regulation of homologous chromosome segregation [GO:0060629]" "chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]" U5 snRNA binding [GO:0030623] 0.95481 -1.5691 GIVEHEEQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.59205 0 0 0 10.2531 0 0 9.71137 0 Q9NZ71 RTEL1_HUMAN Regulator of telomere elongation helicase 1 (EC 3.6.4.12) (Novel helicase-like) RTEL1 C20orf41 KIAA1088 NHL Homo sapiens (Human) DNA duplex unwinding [GO:0032508]; DNA repair [GO:0006281]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of DNA recombination [GO:0045910]; negative regulation of t-circle formation [GO:1904430]; negative regulation of telomere maintenance in response to DNA damage [GO:1904506]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance [GO:0032206]; positive regulation of telomere maintenance via telomere lengthening [GO:1904358]; positive regulation of telomeric loop disassembly [GO:1904535]; regulation of double-strand break repair via homologous recombination [GO:0010569]; replication fork processing [GO:0031297]; strand displacement [GO:0000732]; telomere maintenance [GO:0000723]; telomere maintenance in response to DNA damage [GO:0043247]; telomeric loop disassembly [GO:0090657] "chromosome, telomeric region [GO:0000781]; nuclear membrane [GO:0031965]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]" "4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; DNA polymerase binding [GO:0070182]; metal ion binding [GO:0046872]" 0.89843 -0.64429 ATAPSVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0554 0 0 Q9NZC2 TREM2_HUMAN Triggering receptor expressed on myeloid cells 2 (TREM-2) (Triggering receptor expressed on monocytes 2) TREM2 Homo sapiens (Human) "amyloid-beta clearance by cellular catabolic process [GO:0150094]; apoptotic cell clearance [GO:0043277]; astrocyte activation [GO:0048143]; cellular response to amyloid-beta [GO:1904646]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to lipid [GO:0071396]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to oxidised low-density lipoprotein particle stimulus [GO:0140052]; cellular response to peptidoglycan [GO:0071224]; complement-mediated synapse pruning [GO:0150062]; CXCL12-activated CXCR4 signaling pathway [GO:0038160]; defense response to Gram-negative bacterium [GO:0050829]; dendritic cell differentiation [GO:0097028]; dendritic spine maintenance [GO:0097062]; detection of lipopolysaccharide [GO:0032497]; detection of lipoteichoic acid [GO:0070392]; detection of peptidoglycan [GO:0032499]; excitatory synapse pruning [GO:1905805]; humoral immune response [GO:0006959]; import into cell [GO:0098657]; lipid homeostasis [GO:0055088]; memory [GO:0007613]; microglial cell activation [GO:0001774]; microglial cell activation involved in immune response [GO:0002282]; microglial cell proliferation [GO:0061518]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of astrocyte activation [GO:0061889]; negative regulation of autophagic cell death [GO:1904093]; negative regulation of autophagy [GO:0010507]; negative regulation of cell activation [GO:0050866]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fat cell proliferation [GO:0070345]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of macrophage colony-stimulating factor signaling pathway [GO:1902227]; negative regulation of neuroinflammatory response [GO:0150079]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of sequestering of triglyceride [GO:0010891]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of tumor necrosis factor production [GO:0032720]; osteoclast differentiation [GO:0030316]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of antigen processing and presentation of peptide antigen via MHC class II [GO:0002588]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of C-C chemokine receptor CCR7 signaling pathway [GO:1903082]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of CAMKK-AMPK signaling cascade [GO:1905291]; positive regulation of CD40 signaling pathway [GO:2000350]; positive regulation of chemotaxis [GO:0050921]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of complement activation, classical pathway [GO:0045960]; positive regulation of engulfment of apoptotic cell [GO:1901076]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of establishment of protein localization [GO:1904951]; positive regulation of gene expression [GO:0010628]; positive regulation of high-density lipoprotein particle clearance [GO:0010983]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of inward rectifier potassium channel activity [GO:1901980]; positive regulation of kinase activity [GO:0033674]; positive regulation of low-density lipoprotein particle clearance [GO:1905581]; positive regulation of macrophage fusion [GO:0034241]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of microglial cell migration [GO:1904141]; positive regulation of mitochondrion organization [GO:0010822]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein secretion [GO:0050714]; positive regulation of synapse pruning [GO:1905808]; positive regulation of TOR signaling [GO:0032008]; pyroptosis [GO:0070269]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of gene expression [GO:0010468]; regulation of hippocampal neuron apoptotic process [GO:0110089]; regulation of innate immune response [GO:0045088]; regulation of interleukin-6 production [GO:0032675]; regulation of intracellular signal transduction [GO:1902531]; regulation of lipid metabolic process [GO:0019216]; regulation of macrophage inflammatory protein 1 alpha production [GO:0071640]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of plasma membrane bounded cell projection organization [GO:0120035]; regulation of resting membrane potential [GO:0060075]; regulation of toll-like receptor 6 signaling pathway [GO:0034151]; regulation of TOR signaling [GO:0032006]; respiratory burst after phagocytosis [GO:0045728]; response to axon injury [GO:0048678]; response to ischemia [GO:0002931]; social behavior [GO:0035176]" cell surface [GO:0009986]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853] amyloid-beta binding [GO:0001540]; apolipoprotein A-I binding [GO:0034186]; apolipoprotein binding [GO:0034185]; high-density lipoprotein particle binding [GO:0008035]; kinase activator activity [GO:0019209]; lipid binding [GO:0008289]; lipopolysaccharide binding [GO:0001530]; lipoprotein particle binding [GO:0071813]; lipoteichoic acid binding [GO:0070891]; low-density lipoprotein particle binding [GO:0030169]; molecular function activator activity [GO:0140677]; peptidoglycan binding [GO:0042834]; phosphatidylethanolamine binding [GO:0008429]; phosphatidylserine binding [GO:0001786]; phospholipid binding [GO:0005543]; protein tyrosine kinase binding [GO:1990782]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; signaling receptor activity [GO:0038023]; sulfatide binding [GO:0120146]; transmembrane signaling receptor activity [GO:0004888]; very-low-density lipoprotein particle binding [GO:0034189] 0.42037 0.6714 KVLVEVLADPLDHR 0 10.7405 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NZC9 SMAL1_HUMAN SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.4.-) (HepA-related protein) (hHARP) (Sucrose nonfermenting protein 2-like 1) SMARCAL1 HARP Homo sapiens (Human) DNA damage response [GO:0006974]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; regulation of transcription by RNA polymerase II [GO:0006357]; replication fork processing [GO:0031297]; t-circle formation [GO:0090656] nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861] ATP binding [GO:0005524]; ATP-dependent chromatin remodeler activity [GO:0140658]; ATP-dependent DNA/DNA annealing activity [GO:0036310]; helicase activity [GO:0004386]; hydrolase activity [GO:0016787] 0.94919 -1.3741 LLLADDMGLGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.68314 0 0 0 0 0 0 0 0 Q9NZD2 GLTP_HUMAN Glycolipid transfer protein (GLTP) GLTP Homo sapiens (Human) ER to Golgi ceramide transport [GO:0035621]; glycosphingolipid metabolic process [GO:0006687]; intermembrane lipid transfer [GO:0120009] cytosol [GO:0005829] ceramide 1-phosphate binding [GO:1902387]; ceramide 1-phosphate transfer activity [GO:1902388]; glycolipid binding [GO:0051861]; glycolipid transfer activity [GO:0017089]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; lipid transfer activity [GO:0120013] 0.86366 0.080902 TLQNILEVEKEMYGAEWPK 0 9.37693 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NZD8 SPG21_HUMAN Maspardin (Acid cluster protein 33) (Spastic paraplegia 21 autosomal recessive Mast syndrome protein) (Spastic paraplegia 21 protein) SPG21 ACP33 BM-019 GL010 Homo sapiens (Human) antigen receptor-mediated signaling pathway [GO:0050851] cytosol [GO:0005829]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; trans-Golgi network transport vesicle [GO:0030140] CD4 receptor binding [GO:0042609] 0.89952 -0.61227 FAEYTHK 10.4777 9.11525 9.62311 0 0 0 9.024 8.98533 8.97321 10.0829 10.0358 9.72635 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NZH6 IL37_HUMAN Interleukin-37 (IL-37) (FIL1 zeta) (IL-1X) (Interleukin-1 family member 7) (IL-1F7) (Interleukin-1 homolog 4) (IL-1H) (IL-1H4) (Interleukin-1 zeta) (IL-1 zeta) (Interleukin-1-related protein) (IL-1RP1) IL37 FIL1Z IL1F7 IL1H4 IL1RP1 Homo sapiens (Human) cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of gene expression [GO:0010628]; regulation of inflammatory response [GO:0050727] cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654] cytokine activity [GO:0005125]; interleukin-1 receptor binding [GO:0005149] 0.95141 -1.4387 KHIEFSFQPVCKAEMSPSEVSD 0 0 0 0 0 0 0 0 9.24741 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NZI2 KCIP1_HUMAN Kv channel-interacting protein 1 (KChIP1) (A-type potassium channel modulatory protein 1) (Potassium channel-interacting protein 1) (Vesicle APC-binding protein) KCNIP1 KCHIP1 VABP Homo sapiens (Human) regulation of potassium ion transmembrane transport [GO:1901379] cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; dendrite [GO:0030425]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076] calcium ion binding [GO:0005509]; potassium channel activity [GO:0005267]; potassium channel regulator activity [GO:0015459]; transmembrane transporter binding [GO:0044325]; voltage-gated monoatomic ion channel activity [GO:0005244] 0.89016 -0.46912 DIAWWYYQYQRDK 0 0 0 0 0 0 0 0 0 9.53852 0 0 0 0 0 0 0 0 0 0 9.87869 0 0 0 0 0 0 Q9NZI6 TF2L1_HUMAN Transcription factor CP2-like protein 1 (CP2-related transcriptional repressor 1) (CRTR-1) (Transcription factor LBP-9) TFCP2L1 CRTR1 LBP9 Homo sapiens (Human) cell morphogenesis [GO:0000902]; cytoplasm organization [GO:0007028]; determination of adult lifespan [GO:0008340]; epithelial cell maturation [GO:0002070]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of growth [GO:0045927]; regulation of transcription by RNA polymerase II [GO:0006357]; salivary gland development [GO:0007431] chromatin [GO:0000785]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.90054 -0.69316 LHEETLTYLNQGQSYEIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5773 0 Q9NZJ4 SACS_HUMAN Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) SACS KIAA0730 Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] axon [GO:0030424]; cell body fiber [GO:0070852]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; nucleus [GO:0005634] Hsp70 protein binding [GO:0030544]; identical protein binding [GO:0042802]; proteasome binding [GO:0070628]; protein-folding chaperone binding [GO:0051087] 0.96942 -5.502 ALHYMVQTSTFR 10.5105 0 12.8364 0 0 11.0236 0 10.313 0 9.3771 10.9142 0 9.38944 0 0 10.7779 0 10.6892 0 12.0049 9.02223 0 0 10.4996 0 0 0 Q9NZJ5 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK) EIF2AK3 PEK PERK Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; calcium-mediated signaling [GO:0019722]; cellular response to amino acid starvation [GO:0034198]; cellular response to cold [GO:0070417]; cellular response to glucose starvation [GO:0042149]; chondrocyte development [GO:0002063]; eiF2alpha phosphorylation in response to endoplasmic reticulum stress [GO:0036492]; endocrine pancreas development [GO:0031018]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of myelination [GO:0031642]; negative regulation of translation [GO:0017148]; negative regulation of translation in response to stress [GO:0032055]; negative regulation of translational initiation in response to stress [GO:0032057]; ossification [GO:0001503]; peptidyl-serine phosphorylation [GO:0018105]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of vascular endothelial growth factor production [GO:0010575]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:0060734]; regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902235]; regulation of translational initiation by eIF2 alpha phosphorylation [GO:0010998]; response to endoplasmic reticulum stress [GO:0034976]; response to manganese-induced endoplasmic reticulum stress [GO:1990737]; skeletal system development [GO:0001501] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471] ATP binding [GO:0005524]; enzyme binding [GO:0019899]; eukaryotic translation initiation factor 2alpha kinase activity [GO:0004694]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]; protein phosphatase binding [GO:0019903]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96936 -6.3629 AVGPRSGNEK 0 0 0 0 0 0 11.6392 0 0 0 0 0 0 11.5636 0 0 0 0 9.56786 0 11.2292 0 0 0 0 0 0 Q9NZJ6 COQ3_HUMAN "Ubiquinone biosynthesis O-methyltransferase, mitochondrial (3-demethylubiquinol 3-O-methyltransferase) (EC 2.1.1.64) (Polyprenyldihydroxybenzoate methyltransferase) (EC 2.1.1.114)" COQ3 UG0215E05 Homo sapiens (Human) glycerol metabolic process [GO:0006071]; methylation [GO:0032259]; regulation of ubiquinone biosynthetic process [GO:0010795]; ubiquinone biosynthetic process [GO:0006744] extrinsic component of mitochondrial inner membrane [GO:0031314]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ubiquinone biosynthesis complex [GO:0110142] "2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity [GO:0008425]; 3-demethylubiquinol-10 3-O-methyltransferase activity [GO:0044596]; 3-demethylubiquinone-9 3-O-methyltransferase activity [GO:0008689]; decaprenyldihydroxybenzoate methyltransferase activity [GO:0044595]; hexaprenyldihydroxybenzoate methyltransferase activity [GO:0004395]; O-methyltransferase activity [GO:0008171]" 0.81779 0.22008 LGSSGGWFLR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.731 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NZJ9 NUDT4_HUMAN "Diphosphoinositol polyphosphate phosphohydrolase 2 (DIPP-2) (EC 3.6.1.52) (Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 2) (Nucleoside diphosphate-linked moiety X motif 4) (Nudix motif 4)" NUDT4 DIPP2 KIAA0487 HDCMB47P Homo sapiens (Human) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process [GO:1901911]; calcium-mediated signaling [GO:0019722]; cyclic-nucleotide-mediated signaling [GO:0019935]; diadenosine hexaphosphate catabolic process [GO:1901909]; diadenosine pentaphosphate catabolic process [GO:1901907]; diphosphoinositol polyphosphate metabolic process [GO:0071543]; intracellular signal transduction [GO:0035556] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] "bis(5'-adenosyl)-hexaphosphatase activity [GO:0034431]; bis(5'-adenosyl)-pentaphosphatase activity [GO:0034432]; diphosphoinositol-polyphosphate diphosphatase activity [GO:0008486]; endopolyphosphatase activity [GO:0000298]; inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity [GO:0052848]; inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity [GO:0052845]; metal ion binding [GO:0046872]; snoRNA binding [GO:0030515]" 0.78691 0.2487 LLGIFENQDR 0 0 0 0 0 0 0 0 0 0 0 9.53259 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NZK5 ADA2_HUMAN Adenosine deaminase 2 (EC 3.5.4.4) (Cat eye syndrome critical region protein 1) ADA2 ADGF CECR1 IDGFL Homo sapiens (Human) adenosine catabolic process [GO:0006154]; inosine biosynthetic process [GO:0046103] azurophil granule lumen [GO:0035578]; extracellular region [GO:0005576]; extracellular space [GO:0005615] 2'-deoxyadenosine deaminase activity [GO:0046936]; adenosine deaminase activity [GO:0004000]; adenosine receptor binding [GO:0031685]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; protein homodimerization activity [GO:0042803]; proteoglycan binding [GO:0043394]; zinc ion binding [GO:0008270] 0.87364 0.031999 GLSYDFYEVFMGIGGMK 0 0 0 0 10.0812 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NZK7 PA2GE_HUMAN Group IIE secretory phospholipase A2 (GIIE sPLA2) (sPLA2-IIE) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase 2E) PLA2G2E Homo sapiens (Human) arachidonic acid secretion [GO:0050482]; inflammatory response [GO:0006954]; lipid catabolic process [GO:0016042]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of T cell proliferation [GO:0042130]; phosphatidylcholine metabolic process [GO:0046470]; phosphatidylglycerol metabolic process [GO:0046471]; phospholipid metabolic process [GO:0006644] cytoplasm [GO:0005737]; extracellular region [GO:0005576] calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; phospholipase A2 activity [GO:0004623]; phospholipid binding [GO:0005543] 0.88645 -0.33865 LEKLGCEPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.2765 0 0 Q9NZL3 ZN224_HUMAN Zinc finger protein 224 (Bone marrow zinc finger 2) (BMZF-2) (Zinc finger protein 233) (Zinc finger protein 255) (Zinc finger protein 27) (Zinc finger protein KOX22) ZNF224 BMZF2 KOX22 ZNF233 ZNF255 ZNF27 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122] nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription repressor complex [GO:0017053] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]" 0.8411 0.1804 LNLDMHQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.88891 0 0 0 0 0 Q9NZL4 HPBP1_HUMAN Hsp70-binding protein 1 (HspBP1) (Heat shock protein-binding protein 1) (Hsp70-binding protein 2) (HspBP2) (Hsp70-interacting protein 1) (Hsp70-interacting protein 2) HSPBP1 HSPBP PP1845 Homo sapiens (Human) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457] endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615] adenyl-nucleotide exchange factor activity [GO:0000774]; enzyme inhibitor activity [GO:0004857]; molecular function inhibitor activity [GO:0140678]; molecular sequestering activity [GO:0140313]; ubiquitin protein ligase binding [GO:0031625] 0.96322 -2.6758 LLDRDACDTVRVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.6705 0 0 0 0 0 0 0 0 0 0 0 0 Q9NZL6 RGL1_HUMAN Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1) RGL1 KIAA0959 RGL Homo sapiens (Human) positive regulation of GTPase activity [GO:0043547]; Ras protein signal transduction [GO:0007265]; small GTPase mediated signal transduction [GO:0007264] cytosol [GO:0005829]; plasma membrane [GO:0005886] guanyl-nucleotide exchange factor activity [GO:0005085] 0.92425 -1.0649 SIMLTSQDK 0 0 0 0 0 0 0 0 0 0 9.21427 0 0 0 0 0 0 0 8.39618 0 0 0 0 0 0 0 0 Q9NZM1 MYOF_HUMAN Myoferlin (Fer-1-like protein 3) MYOF FER1L3 KIAA1207 Homo sapiens (Human) blood circulation [GO:0008015]; muscle contraction [GO:0006936]; plasma membrane repair [GO:0001778]; regulation of neurotransmitter secretion [GO:0046928] caveola [GO:0005901]; cytoplasmic vesicle [GO:0031410]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; synaptic vesicle membrane [GO:0030672] calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543] 0.95984 -1.9311 DLTGDQSRSLPYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.72212 9.27594 0 9.43146 0 0 0 9.63751 0 0 0 0 Q9NZM3 ITSN2_HUMAN Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein) ITSN2 KIAA1256 SH3D1B SWAP Homo sapiens (Human) cell differentiation [GO:0030154]; clathrin-dependent synaptic vesicle endocytosis [GO:0150007]; endosomal transport [GO:0016197]; positive regulation of dendrite extension [GO:1903861] centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular vesicle [GO:0097708]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734] calcium ion binding [GO:0005509]; guanyl-nucleotide exchange factor activity [GO:0005085]; molecular adaptor activity [GO:0060090] 0.96885 -5.8633 DTLKAEEK 0 0 0 0 9.54386 0 0 0 0 0 0 0 0 0 0 0 10.2692 9.15117 0 0 0 0 9.2902 0 0 0 10.3557 Q9NZM5 NOP53_HUMAN Ribosome biogenesis protein NOP53 (Glioma tumor suppressor candidate region gene 2 protein) (Protein interacting with carboxyl terminus 1) (PICT-1) (p60) NOP53 GLT GLTSCR2 PICT1 Homo sapiens (Human) cellular response to hypoxia [GO:0071456]; DNA damage response [GO:0006974]; DNA repair [GO:0006281]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901837]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; protein localization to nucleolus [GO:1902570]; protein localization to nucleoplasm [GO:1990173]; protein stabilization [GO:0050821]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of protein phosphorylation [GO:0001932]; regulation of RIG-I signaling pathway [GO:0039535]; regulation of signal transduction by p53 class mediator [GO:1901796]; ribosomal large subunit assembly [GO:0000027]; rRNA processing [GO:0006364] cytosol [GO:0005829]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] 5S rRNA binding [GO:0008097]; identical protein binding [GO:0042802]; p53 binding [GO:0002039]; RNA binding [GO:0003723] 0.95969 -1.9384 LAKQGELPREVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1438 0 0 Q9NZM6 PK2L2_HUMAN Polycystin-2-like protein 2 (Polycystin-2L2) (Polycystic kidney disease 2-like 2 protein) (Polycystin-L2) PKD2L2 Homo sapiens (Human) detection of mechanical stimulus [GO:0050982] membrane [GO:0016020] calcium channel activity [GO:0005262]; calcium ion binding [GO:0005509] 0.96761 -3.7395 AEASRWHR 0 0 8.9611 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.90603 0 0 0 0 0 0 0 0 0 Q9NZN5 ARHGC_HUMAN Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF) ARHGEF12 KIAA0382 LARG Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020] G protein-coupled receptor binding [GO:0001664]; GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085] 0.97013 -3.2372 LTKYPLLLDNIAK 0 0 0 0 0 8.55055 0 11.0253 8.31188 0 0 0 10.6812 11.4921 0 10.267 0 0 10.453 0 0 0 0 0 0 9.84582 0 Q9NZN8 CNOT2_HUMAN CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2) CNOT2 CDC36 NOT2 HSPC131 MSTP046 Homo sapiens (Human) "negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; regulation of stem cell population maintenance [GO:2000036]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; RNA-mediated gene silencing [GO:0031047]; trophectodermal cell differentiation [GO:0001829]" CCR4-NOT complex [GO:0030014]; CCR4-NOT core complex [GO:0030015]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; plasma membrane [GO:0005886] transcription coregulator activity [GO:0003712]; transcription corepressor binding [GO:0001222] 0.91899 -0.89047 DPTSSNDDSK 0 0 0 0 0 0 0 9.42362 0 11.1304 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6126 0 Q9NZN9 AIPL1_HUMAN Aryl-hydrocarbon-interacting protein-like 1 AIPL1 AIPL2 Homo sapiens (Human) "apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; phototransduction, visible light [GO:0007603]; protein farnesylation [GO:0018343]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; photoreceptor inner segment [GO:0001917] farnesylated protein binding [GO:0001918]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082] 0.96137 -2.5648 LEVWEILLTSMR 0 0 0 0 0 0 0 0 0 0 0 0 9.17978 10.4169 0 0 0 10.086 0 10.4835 0 0 0 0 0 10.9783 0 Q9NZP2 OR6C2_HUMAN Olfactory receptor 6C2 (HSA3) OR6C2 Homo sapiens (Human) sensory perception of smell [GO:0007608] membrane [GO:0016020]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.91549 -0.80567 FPSVQQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.80726 0 0 0 0 0 0 0 0 Q9NZP6 NPAP1_HUMAN Nuclear pore-associated protein 1 NPAP1 C15orf2 Homo sapiens (Human) cell differentiation [GO:0030154]; protein import into nucleus [GO:0006606]; RNA export from nucleus [GO:0006405]; spermatogenesis [GO:0007283] intracellular membrane-bounded organelle [GO:0043231]; nuclear inner membrane [GO:0005637]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] nuclear localization sequence binding [GO:0008139]; structural constituent of nuclear pore [GO:0017056] 0.91442 -0.81983 KTPMLPAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.2363 0 0 0 0 0 0 0 0 0 0 0 Q9NZQ3 SPN90_HUMAN NCK-interacting protein with SH3 domain (54 kDa VacA-interacting protein) (54 kDa vimentin-interacting protein) (VIP54) (90 kDa SH3 protein interacting with Nck) (AF3p21) (Dia-interacting protein 1) (DIP-1) (Diaphanous protein-interacting protein) (SH3 adapter protein SPIN90) (WASP-interacting SH3-domain protein) (WISH) (Wiskott-Aldrich syndrome protein-interacting protein) NCKIPSD AF3P21 SPIN90 Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endocytosis [GO:0006897]; positive regulation of neuron projection development [GO:0010976] cytosol [GO:0005829]; intermediate filament [GO:0005882]; nucleus [GO:0005634] Arp2/3 complex binding [GO:0071933]; cytoskeletal protein binding [GO:0008092]; SH3 domain binding [GO:0017124] 0.5 0.61149 MEYLSLMHAIVR 0 0 0 8.77752 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NZQ8 TRPM5_HUMAN Transient receptor potential cation channel subfamily M member 5 (Long transient receptor potential channel 5) (LTrpC-5) (LTrpC5) (MLSN1- and TRP-related gene 1 protein) TRPM5 LTRPC5 MTR1 Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; regulation of monoatomic ion transmembrane transport [GO:0034765] dendrite [GO:0030425]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886] calcium activated cation channel activity [GO:0005227]; ligand-gated calcium channel activity [GO:0099604]; monoatomic ion channel activity [GO:0005216]; potassium channel activity [GO:0005267]; sodium channel activity [GO:0005272]; voltage-gated monoatomic ion channel activity [GO:0005244] 0.93174 -1.2701 DLPDPLDQK 0 0 0 0 0 0 0 0 0 13.7366 0 0 0 10.2087 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NZQ9 TMOD4_HUMAN Tropomodulin-4 (Skeletal muscle tropomodulin) (Sk-Tmod) TMOD4 Homo sapiens (Human) muscle contraction [GO:0006936]; myofibril assembly [GO:0030239]; pointed-end actin filament capping [GO:0051694] striated muscle thin filament [GO:0005865] actin binding [GO:0003779]; tropomyosin binding [GO:0005523] 0.88259 -0.11362 FGYHFTQQGPRARAAQAMTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.72305 0 Q9NZR1 TMOD2_HUMAN Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod) TMOD2 NTMOD Homo sapiens (Human) learning or memory [GO:0007611]; muscle contraction [GO:0006936]; myofibril assembly [GO:0030239]; nervous system development [GO:0007399]; neuron-neuron synaptic transmission [GO:0007270]; pointed-end actin filament capping [GO:0051694]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; synapse [GO:0045202] actin binding [GO:0003779]; tropomyosin binding [GO:0005523] 0.92382 -1.0467 EALEQKDR 0 0 0 0 0 0 0 9.10693 9.35971 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NZR2 LRP1B_HUMAN Low-density lipoprotein receptor-related protein 1B (LRP-1B) (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT) LRP1B LRPDIT Homo sapiens (Human) protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] plasma membrane [GO:0005886]; receptor complex [GO:0043235] calcium ion binding [GO:0005509]; low-density lipoprotein particle receptor activity [GO:0005041] 0.96941 -3.4635 ATALTIMDK 9.20347 0 0 0 0 0 0 0 0 0 10.325 10.5131 10.4173 0 0 0 0 0 0 9.07245 0 0 0 0 0 9.99067 0 Q9NZR4 VSX1_HUMAN Visual system homeobox 1 (Homeodomain protein RINX) (Retinal inner nuclear layer homeobox protein) (Transcription factor VSX1) VSX1 RINX Homo sapiens (Human) neuron development [GO:0048666]; neuron maturation [GO:0042551]; regulation of DNA-templated transcription [GO:0006355]; response to stimulus [GO:0050896]; retinal bipolar neuron differentiation [GO:0060040]; visual perception [GO:0007601] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]" 0.46349 0.63352 DSLSDGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.37469 0 0 0 0 0 8.76835 0 0 Q9NZT2 OGFR_HUMAN Opioid growth factor receptor (OGFr) (Protein 7-60) (Zeta-type opioid receptor) OGFR Homo sapiens (Human) regulation of cell growth [GO:0001558] cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleus [GO:0005634] opioid growth factor receptor activity [GO:0140625] 0.95572 -1.5463 GTGTVGRAQNYQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1122 0 0 0 0 0 0 Q9NZU0 FLRT3_HUMAN Leucine-rich repeat transmembrane protein FLRT3 (Fibronectin-like domain-containing leucine-rich transmembrane protein 3) FLRT3 KIAA1469 UNQ856/PRO1865 Homo sapiens (Human) axon guidance [GO:0007411]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; embryonic morphogenesis [GO:0048598]; fibroblast growth factor receptor signaling pathway [GO:0008543]; head development [GO:0060322]; heart development [GO:0007507]; neuron projection development [GO:0031175]; neuron projection extension [GO:1990138]; positive regulation of synapse assembly [GO:0051965]; proepicardium cell migration involved in pericardium morphogenesis [GO:0003345]; response to axon injury [GO:0048678]; synapse assembly [GO:0007416]; synaptic membrane adhesion [GO:0099560] axon terminus [GO:0043679]; axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone membrane [GO:0032584]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; synaptic membrane [GO:0097060] chemorepellent activity [GO:0045499]; fibroblast growth factor receptor binding [GO:0005104]; protein homodimerization activity [GO:0042803]; protein-macromolecule adaptor activity [GO:0030674] 0.96445 -2.3817 QPDIKNPKLTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8987 0 0 0 0 0 0 0 0 0 Q9NZU1 FLRT1_HUMAN Leucine-rich repeat transmembrane protein FLRT1 (Fibronectin-like domain-containing leucine-rich transmembrane protein 1) FLRT1 UNQ752/PRO1483 Homo sapiens (Human) cell adhesion [GO:0007155]; dendrite development [GO:0016358]; fibroblast growth factor receptor signaling pathway [GO:0008543]; neuron projection extension [GO:1990138] cell-cell junction [GO:0005911]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; endoplasmic reticulum membrane [GO:0005789]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; neuron projection terminus [GO:0044306]; neuronal cell body membrane [GO:0032809]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] protein-macromolecule adaptor activity [GO:0030674] 0.8837 -0.32807 ATLPASSFR 0 0 12.098 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NZU5 LMCD1_HUMAN LIM and cysteine-rich domains protein 1 (Dyxin) LMCD1 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; regulation of cardiac muscle hypertrophy [GO:0010611] cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] transcription corepressor activity [GO:0003714]; zinc ion binding [GO:0008270] 0.92184 -1.1358 GLLENELK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3923 0 0 0 0 10.3375 0 0 0 Q9NZU7 CABP1_HUMAN Calcium-binding protein 1 (CaBP1) (Calbrain) (Caldendrin) CABP1 Homo sapiens (Human) negative regulation of protein import into nucleus [GO:0042308]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to stimulus [GO:0050896]; visual perception [GO:0007601] cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; enzyme inhibitor activity [GO:0004857]; nuclear localization sequence binding [GO:0008139] 0.95253 -1.4594 EFDTNGDGEISTSELREAMRK 0 0 0 0 0 0 0 0 0 0 0 0 10.9566 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9NZV1 CRIM1_HUMAN Cysteine-rich motor neuron 1 protein (CRIM-1) (Cysteine-rich repeat-containing protein S52) [Cleaved into: Processed cysteine-rich motor neuron 1 protein] CRIM1 S52 UNQ1886/PRO4330 Homo sapiens (Human) negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of osteoblast differentiation [GO:0045668]; nervous system development [GO:0007399] extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886] insulin-like growth factor receptor activity [GO:0005010]; PDZ domain binding [GO:0030165]; serine-type endopeptidase inhibitor activity [GO:0004867] 0.96953 -6.0194 GDGTPGK 0 0 0 0 0 0 0 0 0 0 9.84984 0 0 0 0 0 0 8.42538 0 0 0 0 0 0 8.97559 0 9.63552 Q9NZV5 SELN_HUMAN Selenoprotein N (SelN) SELENON SELN SEPN1 Homo sapiens (Human) calcium ion homeostasis [GO:0055074]; cellular response to caffeine [GO:0071313]; cellular response to oxidative stress [GO:0034599]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; multicellular organismal response to stress [GO:0033555]; positive regulation of response to oxidative stress [GO:1902884]; positive regulation of skeletal muscle cell proliferation [GO:0014858]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; respiratory system process [GO:0003016]; response to muscle activity involved in regulation of muscle adaptation [GO:0014873]; skeletal muscle fiber development [GO:0048741]; skeletal muscle satellite cell differentiation [GO:0014816]; skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration [GO:0014834] endoplasmic reticulum membrane [GO:0005789] calcium ion binding [GO:0005509]; oxidoreductase activity [GO:0016491] 0.44041 0.64784 WQQELSWEEAARR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.53091 0 0 Q9NZV7 ZIM2_HUMAN Zinc finger imprinted 2 (Zinc finger protein 656) ZIM2 ZNF656 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] DNA binding [GO:0003677]; zinc ion binding [GO:0008270] 0.95254 -1.46 HQKTHSGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.78555 9.31245 0 0 0 0 Q9NZV8 KCND2_HUMAN Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2) KCND2 KIAA1044 Homo sapiens (Human) action potential [GO:0001508]; cellular response to hypoxia [GO:0071456]; chemical synaptic transmission [GO:0007268]; locomotor rhythm [GO:0045475]; neuronal action potential [GO:0019228]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of monoatomic ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233] anchoring junction [GO:0070161]; dendritic spine [GO:0043197]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; neuronal cell body membrane [GO:0032809]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization membrane [GO:0099634]; voltage-gated potassium channel complex [GO:0008076] A-type (transient outward) potassium channel activity [GO:0005250]; metal ion binding [GO:0046872]; voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential [GO:1905030]; voltage-gated potassium channel activity [GO:0005249] 0.96138 -2.5603 TPLSNSR 0 0 0 0 0 0 0 0 8.2778 0 0 0 0 0 0 0 0 0 8.97997 0 0 0 0 0 0 0 0 Q9NZW5 PALS2_HUMAN "Protein PALS2 (MAGUK p55 subfamily member 6) (Membrane protein, palmitoylated 6) (Veli-associated MAGUK 1) (VAM-1)" PALS2 MPP6 VAM1 Homo sapiens (Human) protein-containing complex assembly [GO:0065003] cell-cell junction [GO:0005911]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886] 0.95436 -1.5124 EDEKDGQAYK 0 0 0 0 0 0 12.2458 12.0195 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P015 RM15_HUMAN "Large ribosomal subunit protein uL15m (39S ribosomal protein L15, mitochondrial) (L15mt) (MRP-L15)" MRPL15 HSPC145 Homo sapiens (Human) cellular response to leukemia inhibitory factor [GO:1990830]; mitochondrial translation [GO:0032543] mitochondrial inner membrane [GO:0005743]; mitochondrial large ribosomal subunit [GO:0005762]; mitochondrion [GO:0005739] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.82244 0.21714 YGFNEGHSFR 0 0 0 0 0 0 0 0 0 9.72773 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P031 TAP26_HUMAN Thyroid transcription factor 1-associated protein 26 (TTF-1-associated protein 26) (Coiled-coil domain-containing protein 59) (TTF-1-associated protein BR2) CCDC59 BR22 TAP26 HSPC128 Homo sapiens (Human) nucleoplasm [GO:0005654] RNA binding [GO:0003723] 0.95415 -1.5163 GEGVSTVGYRNK 0 0 0 0 0 0 0 0 0 0 9.31485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P035 HACD3_HUMAN Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase 3) (HACD3) (Butyrate-induced protein 1) (B-ind1) (hB-ind1) (Protein-tyrosine phosphatase-like A domain-containing protein 1) HACD3 BIND1 PTPLAD1 Homo sapiens (Human) fatty acid elongation [GO:0030497]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; JNK cascade [GO:0007254]; positive regulation by virus of viral protein levels in host cell [GO:0046726]; positive regulation of viral genome replication [GO:0045070]; Rac protein signal transduction [GO:0016601]; Rho protein signal transduction [GO:0007266]; small GTPase mediated signal transduction [GO:0007264]; sphingolipid biosynthetic process [GO:0030148]; very long-chain fatty acid biosynthetic process [GO:0042761] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; focal adhesion [GO:0005925]; nuclear membrane [GO:0031965] 3-hydroxyacyl-CoA dehydratase activity [GO:0018812]; enzyme binding [GO:0019899]; GTPase activator activity [GO:0005096] 0.6764 0.39371 AQGHGAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.28873 0 0 0 0 0 Q9P086 MED11_HUMAN Mediator of RNA polymerase II transcription subunit 11 (Mediator complex subunit 11) MED11 HSPC296 Homo sapiens (Human) positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; protein ubiquitination [GO:0016567]; RNA polymerase II preinitiation complex assembly [GO:0051123] core mediator complex [GO:0070847]; mediator complex [GO:0016592]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151] transcription coregulator activity [GO:0003712]; ubiquitin protein ligase activity [GO:0061630] 0.84411 0.15301 TCEQMLEN 0 0 0 0 0 0 9.30752 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P0G3 KLK14_HUMAN Kallikrein-14 (hK14) (EC 3.4.21.-) (Kallikrein-like protein 6) (KLK-L6) KLK14 KLKL6 Homo sapiens (Human) epidermis morphogenesis [GO:0048730]; fertilization [GO:0009566]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; proteolysis [GO:0006508]; seminal clot liquefaction [GO:0070684] extracellular region [GO:0005576]; extracellular space [GO:0005615] serine-type endopeptidase activity [GO:0004252] 0.84703 0.1705 SWIEETMR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3309 Q9P0J1 PDP1_HUMAN "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial (PDP 1) (EC 3.1.3.43) (Protein phosphatase 2C) (Pyruvate dehydrogenase phosphatase catalytic subunit 1) (PDPC 1)" PDP1 PDP PPM2C Homo sapiens (Human) peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of pyruvate dehydrogenase activity [GO:1904184]; protein dephosphorylation [GO:0006470] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; pyruvate dehydrogenase (lipoamide) phosphatase complex [GO:0045253] [pyruvate dehydrogenase (lipoamide)] phosphatase activity [GO:0004741]; [pyruvate dehydrogenase (lipoamide)] phosphatase regulator activity [GO:0019909]; metal ion binding [GO:0046872]; protein serine/threonine phosphatase activity [GO:0004722] 0.93274 -1.2657 LKLEHPKSEAK 0 0 0 0 0 9.8997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P0J7 KCMF1_HUMAN E3 ubiquitin-protein ligase KCMF1 (EC 2.3.2.27) (FGF-induced in gastric cancer) (Potassium channel modulatory factor) (PCMF) (RING-type E3 ubiquitin transferase KCMF1) (ZZ-type zinc finger-containing protein 1) KCMF1 FIGC ZZZ1 Homo sapiens (Human) synaptic signaling [GO:0099536] cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; plasma membrane [GO:0005886]; synapse [GO:0045202] ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.96762 -2.7515 GLGGPRAR 0 0 0 0 0 0 0 0 0 12.6189 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P0K1 ADA22_HUMAN "Disintegrin and metalloproteinase domain-containing protein 22 (ADAM 22) (Metalloproteinase-disintegrin ADAM22-3) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2)" ADAM22 MDC2 Homo sapiens (Human) cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; negative regulation of cell adhesion [GO:0007162]; proteolysis [GO:0006508] axon [GO:0030424]; membrane [GO:0016020]; plasma membrane [GO:0005886] integrin binding [GO:0005178]; metalloendopeptidase activity [GO:0004222] 0.91765 -0.85852 EQRQLPQGDYVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5816 0 0 0 0 0 0 Q9P0K7 RAI14_HUMAN Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Novel retinal pigment epithelial cell protein) (Retinoic acid-induced protein 14) RAI14 KIAA1334 NORPEG Homo sapiens (Human) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] anchoring junction [GO:0070161]; cell cortex [GO:0005938]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654] actin binding [GO:0003779] 0.96897 -5.7795 AEHEKLMQLTNVSRAK 0 11.4809 0 10.5624 0 10.2271 0 0 0 0 0 0 0 11.1912 11.2804 11.8871 11.636 0 0 0 10.1297 0 0 0 10.8111 0 0 Q9P0K8 FOXJ2_HUMAN Forkhead box protein J2 (Fork head homologous X) FOXJ2 FHX Homo sapiens (Human) cell differentiation [GO:0030154]; male meiosis I [GO:0007141]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell differentiation [GO:0110059]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283] chromatin [GO:0000785]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.889 -0.45078 CFRKVPRPR 0 0 0 0 0 0 0 0 0 0 0 9.10468 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P0L2 MARK1_HUMAN Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase 1) (PAR1 homolog c) (Par-1c) (Par1c) MARK1 KIAA1477 MARK Homo sapiens (Human) cytoskeleton organization [GO:0007010]; establishment of mitochondrion localization [GO:0051654]; intracellular signal transduction [GO:0035556]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of gene expression [GO:0010629]; neuron migration [GO:0001764]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]; regulation of dendrite development [GO:0050773]; regulation of neuron projection development [GO:0010975]; Wnt signaling pathway [GO:0016055] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dendrite [GO:0030425]; microtubule cytoskeleton [GO:0015630]; plasma membrane [GO:0005886] "ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphatidic acid binding [GO:0070300]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321]" 0.92324 -1.1502 IDIMVTMGFAR 0 12.6805 0 0 0 0 0 12.7414 0 0 0 0 0 9.27277 0 0 0 10.3782 0 0 0 0 0 0 0 0 0 Q9P0L9 PK2L1_HUMAN Polycystin-2-like protein 1 (Polycystin-2L1) (Polycystic kidney disease 2-like 1 protein) (Polycystin-2 homolog) (Polycystin-L) (Polycystin-L1) PKD2L1 PKD2L PKDL TRPP3 Homo sapiens (Human) cellular response to acidic pH [GO:0071468]; detection of chemical stimulus involved in sensory perception of sour taste [GO:0001581]; detection of chemical stimulus involved in sensory perception of taste [GO:0050912]; detection of mechanical stimulus [GO:0050982]; inorganic cation transmembrane transport [GO:0098662]; monoatomic cation transport [GO:0006812]; potassium ion transmembrane transport [GO:0071805]; protein homotetramerization [GO:0051289]; response to water [GO:0009415]; sensory perception of sour taste [GO:0050915]; smoothened signaling pathway [GO:0007224]; sodium ion transmembrane transport [GO:0035725] actin cytoskeleton [GO:0015629]; calcium channel complex [GO:0034704]; cell surface [GO:0009986]; ciliary membrane [GO:0060170]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; non-motile cilium [GO:0097730]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] alpha-actinin binding [GO:0051393]; calcium activated cation channel activity [GO:0005227]; calcium channel activity [GO:0005262]; calcium ion binding [GO:0005509]; calcium-activated potassium channel activity [GO:0015269]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; monoatomic cation channel activity [GO:0005261]; muscle alpha-actinin binding [GO:0051371]; sodium channel activity [GO:0005272]; sour taste receptor activity [GO:0033040] 0.89144 -0.50533 LKMLERK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.41576 0 0 0 0 0 0 Q9P0M2 AKA7G_HUMAN A-kinase anchor protein 7 isoform gamma (AKAP-7 isoform gamma) (A-kinase anchor protein 18 kDa) (AKAP 18) (Protein kinase A-anchoring protein 7 isoform gamma) (PRKA7 isoform gamma) AKAP7 AKAP18 Homo sapiens (Human) modulation of chemical synaptic transmission [GO:0050804]; regulation of protein kinase A signaling [GO:0010738] cytosol [GO:0005829]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] nucleotide binding [GO:0000166]; protein kinase A binding [GO:0051018]; protein kinase A regulatory subunit binding [GO:0034237]; protein kinase binding [GO:0019901] 0.91511 -0.77739 GIKILQNAIIQQDER 0 9.76847 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P0P8 MRES1_HUMAN Mitochondrial transcription rescue factor 1 MTRES1 C6orf203 HSPC230 Homo sapiens (Human) regulation of mitochondrial transcription [GO:1903108]; rescue of stalled ribosome [GO:0072344] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] ribosomal large subunit binding [GO:0043023]; RNA binding [GO:0003723]; tRNA binding [GO:0000049] 0.66963 0.39399 MAMASVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.20975 0 0 0 0 0 0 0 0 Q9P0T4 ZN581_HUMAN Zinc finger protein 581 ZNF581 HSPC189 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.88251 -0.067967 DAGELAQHSR 0 0 0 0 0 0 0 0 0 0 0 9.80649 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P0T7 TMEM9_HUMAN Proton-transporting V-type ATPase complex assembly regulator TMEM9 (v-ATPase assembly regulator TMEM9) (Dermal papilla-derived protein 4) (Transmembrane protein 9) (Protein TMEM9) TMEM9 DERP4 TMEM9A HSPC186 PSEC0012 UNQ631/PRO1248 Homo sapiens (Human) endosomal lumen acidification [GO:0048388]; lysosomal lumen acidification [GO:0007042]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein transport [GO:0015031]; proton-transporting V-type ATPase complex assembly [GO:0070070]; regulation of protein catabolic process [GO:0042176] intercellular bridge [GO:0045171]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; microtubule cytoskeleton [GO:0015630]; mitotic spindle [GO:0072686]; multivesicular body membrane [GO:0032585] 0.96947 -5.6058 TVFDRHK 0 0 0 0 0 0 0 0 0 0 8.92867 0 0 0 0 0 0 0 0 8.92032 0 0 0 0 0 0 0 Q9P0U3 SENP1_HUMAN Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1) SENP1 Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic signaling pathway [GO:0097190]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein desumoylation [GO:0016926]; protein sumoylation [GO:0016925]; proteolysis [GO:0006508] cytoplasm [GO:0005737]; focal adhesion [GO:0005925]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] deSUMOylase activity [GO:0016929]; endopeptidase activity [GO:0004175]; SUMO-specific endopeptidase activity [GO:0070139] 0.8843 -0.21007 ELTSVYDSRAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0042 0 Q9P0U4 CXXC1_HUMAN CXXC-type zinc finger protein 1 (CpG-binding protein) (PHD finger and CXXC domain-containing protein 1) CXXC1 CFP1 CGBP PCCX1 PHF18 Homo sapiens (Human) histone H3-K4 methylation [GO:0051568]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription [GO:0006355] cytosol [GO:0005829]; histone methyltransferase complex [GO:0035097]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188] cis-regulatory region sequence-specific DNA binding [GO:0000987]; methylated histone binding [GO:0035064]; unmethylated CpG binding [GO:0045322]; zinc ion binding [GO:0008270] 0.90597 -0.72333 AGSGTGVGAMLAR 0 0 0 9.22795 0 9.72306 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P0V3 SH3B4_HUMAN SH3 domain-binding protein 4 (EH-binding protein 10) (Transferrin receptor-trafficking protein) SH3BP4 BOG25 EHB10 TTP Homo sapiens (Human) cellular response to amino acid stimulus [GO:0071230]; endocytosis [GO:0006897]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of GTPase activity [GO:0034260]; negative regulation of TOR signaling [GO:0032007]; positive regulation of autophagy [GO:0010508]; protein localization to lysosome [GO:0061462]; regulation of catalytic activity [GO:0050790] clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleus [GO:0005634] GDP-dissociation inhibitor activity [GO:0005092]; identical protein binding [GO:0042802]; small GTPase binding [GO:0031267] 0.88911 -0.43036 ELVMALLKMDCQGLVVR 0 0 0 0 0 0 0 0 0 0 9.59694 9.50468 0 0 0 0 0 0 0 0 0 0 10.5075 0 0 0 0 Q9P0V9 SEP10_HUMAN Septin-10 SEPTIN10 SEPT10 Homo sapiens (Human) cytoskeleton-dependent cytokinesis [GO:0061640] cell division site [GO:0032153]; microtubule cytoskeleton [GO:0015630]; motile cilium [GO:0031514]; septin complex [GO:0031105]; septin ring [GO:0005940] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; molecular adaptor activity [GO:0060090] 0.88074 0.011187 TTCMSSQGSDDEQIK 0 0 0 0 0 9.07756 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P0W8 SPAT7_HUMAN Spermatogenesis-associated protein 7 (HSD-3.1) (Spermatogenesis-associated protein HSD3) SPATA7 HSD3 Homo sapiens (Human) microtubule cytoskeleton organization [GO:0000226]; photoreceptor cell maintenance [GO:0045494]; protein localization to photoreceptor connecting cilium [GO:1903621]; protein localization to photoreceptor outer segment [GO:1903546]; response to stimulus [GO:0050896]; visual perception [GO:0007601] axoneme [GO:0005930]; ciliary basal body [GO:0036064]; cytosol [GO:0005829]; microtubule cytoskeleton [GO:0015630]; photoreceptor connecting cilium [GO:0032391]; photoreceptor distal connecting cilium [GO:0120206]; rod photoreceptor outer segment [GO:0120200] 0.96968 -4.0702 ATSVLPR 0 0 0 0 0 0 0 0 0 15.3772 13.7193 0 0 0 13.1774 0 12.8097 0 0 0 0 0 0 0 0 9.89209 0 Q9P0X4 CAC1I_HUMAN Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage-gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3) CACNA1I KIAA1120 Homo sapiens (Human) calcium ion import across plasma membrane [GO:0098703]; neuronal action potential [GO:0019228]; regulation of monoatomic ion transmembrane transport [GO:0034765]; signal transduction [GO:0007165]; sleep [GO:0030431] plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891] high voltage-gated calcium channel activity [GO:0008331]; voltage-gated calcium channel activity [GO:0005245] 0.95284 -1.4736 EHRLMLEQR 0 0 0 0 0 0 0 0 0 10.3216 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P104 DOK5_HUMAN Docking protein 5 (Downstream of tyrosine kinase 5) (Insulin receptor substrate 6) (IRS-6) (IRS6) DOK5 C20orf180 Homo sapiens (Human) neuron differentiation [GO:0030182]; positive regulation of MAPK cascade [GO:0043410]; Ras protein signal transduction [GO:0007265]; regulation of neurotrophin TRK receptor signaling pathway [GO:0051386]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] cytoplasm [GO:0005737]; cytosol [GO:0005829] 0.94606 -1.3436 RLGIYQRCWLVFK 10.0053 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P107 GMIP_HUMAN GEM-interacting protein (GMIP) GMIP Homo sapiens (Human) activation of GTPase activity [GO:0090630]; intracellular signal transduction [GO:0035556]; negative regulation of GTPase activity [GO:0034260]; regulation of small GTPase mediated signal transduction [GO:0051056] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] GTPase activator activity [GO:0005096]; metal ion binding [GO:0046872] 0.9525 -1.4574 QQDLEIAKQR 0 0 0 0 0 0 0 0 0 11.9082 11.733 11.9641 0 0 0 0 0 0 0 0 0 0 0 0 9.49741 0 0 Q9P109 GCNT4_HUMAN "Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 (EC 2.4.1.102) (Core 2-branching enzyme 3) (Core2-GlcNAc-transferase 3) (C2GnT3)" GCNT4 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; inter-male aggressive behavior [GO:0002121]; kidney morphogenesis [GO:0060993]; neutrophil homeostasis [GO:0001780]; O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493]; thyroid hormone metabolic process [GO:0042403]; tissue morphogenesis [GO:0048729] Golgi membrane [GO:0000139] "acetylglucosaminyltransferase activity [GO:0008375]; beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity [GO:0003829]; N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity [GO:0008109]" 0.91409 -0.82491 SSIQWKYVINLCGQDFPLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.86527 0 Q9P121 NTRI_HUMAN Neurotrimin (hNT) (IgLON family member 2) NTM IGLON2 NT UNQ297/PRO337 Homo sapiens (Human) cell adhesion [GO:0007155]; neuron recognition [GO:0008038] extracellular region [GO:0005576]; plasma membrane [GO:0005886] 0.92379 -1.1617 CLVVVSLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2261 0 0 10.299 10.0794 0 0 0 0 0 0 0 0 Q9P126 CLC1B_HUMAN C-type lectin domain family 1 member B (C-type lectin-like receptor 2) (CLEC-2) CLEC1B CLEC2 UNQ721/PRO1384 Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; defense response [GO:0006952]; platelet formation [GO:0030220]; signal transduction [GO:0007165] cell surface [GO:0009986]; plasma membrane [GO:0005886] carbohydrate binding [GO:0030246]; transmembrane signaling receptor activity [GO:0004888] 0.86072 0.092804 FCQYVVKQSELK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.47431 0 0 0 0 0 0 0 0 0 0 Q9P127 LUZP4_HUMAN Leucine zipper protein 4 (Cancer/testis antigen 28) (CT-28) (CT28) (Tumor antigen HOM-TES-85) LUZP4 Homo sapiens (Human) mRNA transport [GO:0051028] cytoplasm [GO:0005737]; nucleus [GO:0005634] RNA binding [GO:0003723] 0.84965 0.12185 SLSQSDRSQGQLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.35797 0 0 Q9P1A2 PP4RL_HUMAN Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like PPP4R1L C20orf192 PRO1085 Homo sapiens (Human) 0.88365 -0.10884 LLLPRFCELCGDRK 0 0 0 0 0 0 0 0 0 0 0 0 9.27796 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P1A6 DLGP2_HUMAN Disks large-associated protein 2 (DAP-2) (PSD-95/SAP90-binding protein 2) (SAP90/PSD-95-associated protein 2) (SAPAP2) DLGAP2 C8orf68 DAP2 ERICH1-AS1 Homo sapiens (Human) neuron-neuron synaptic transmission [GO:0007270]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] glutamatergic synapse [GO:0098978]; neurofilament [GO:0005883]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic specialization [GO:0099572] molecular adaptor activity [GO:0060090] 0.95295 -1.4735 HSEPSTPTQYSAVRTVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.56982 0 0 0 0 0 Q9P1P5 TAAR2_HUMAN Trace amine-associated receptor 2 (TaR-2) (Trace amine receptor 2) (G-protein coupled receptor 58) TAAR2 GPR58 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; trace-amine receptor activity [GO:0001594] 0.85049 0.15903 SVENCWYFGLTFCK 0 0 0 0 0 0 0 0 0 10.3015 0 0 0 0 0 0 0 0 10.224 0 0 0 0 0 0 0 0 Q9P1Q0 VPS54_HUMAN Vacuolar protein sorting-associated protein 54 (Hepatocellular carcinoma protein 8) (Tumor antigen HOM-HCC-8) (Tumor antigen SLP-8p) VPS54 HCC8 Homo sapiens (Human) "apoptotic DNA fragmentation [GO:0006309]; astrocyte differentiation [GO:0048708]; cellular response to progesterone stimulus [GO:0071393]; gene expression [GO:0010467]; Golgi to vacuole transport [GO:0006896]; homeostasis of number of cells within a tissue [GO:0048873]; in utero embryonic development [GO:0001701]; intracellular calcium ion homeostasis [GO:0006874]; L-glutamate import [GO:0051938]; lysosomal transport [GO:0007041]; microglia differentiation [GO:0014004]; mitochondrion organization [GO:0007005]; motor behavior [GO:0061744]; motor neuron apoptotic process [GO:0097049]; musculoskeletal movement [GO:0050881]; negative regulation of motor neuron apoptotic process [GO:2000672]; neural tissue regeneration [GO:0097719]; neurofilament cytoskeleton organization [GO:0060052]; neuroinflammatory response [GO:0150076]; neuromuscular synaptic transmission [GO:0007274]; neuron projection morphogenesis [GO:0048812]; post-embryonic forelimb morphogenesis [GO:0035128]; protein localization to cell surface [GO:0034394]; protein targeting to ER [GO:0045047]; protein targeting to lysosome [GO:0006622]; regulation of growth [GO:0040008]; respiratory electron transport chain [GO:0022904]; response to antibiotic [GO:0046677]; response to calcium ion [GO:0051592]; retrograde transport, endosome to Golgi [GO:0042147]; skeletal muscle tissue growth [GO:0048630]; spermatid differentiation [GO:0048515]; sphingolipid catabolic process [GO:0030149]; striated muscle contraction [GO:0006941]; synaptic transmission, GABAergic [GO:0051932]; synaptic transmission, glutamatergic [GO:0035249]; thrombin-activated receptor signaling pathway [GO:0070493]; ubiquitin recycling [GO:0010992]; vacuole organization [GO:0007033]; vesicle-mediated cholesterol transport [GO:0090119]" cytosol [GO:0005829]; GARP complex [GO:0000938]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; synapse [GO:0045202]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588] syntaxin binding [GO:0019905] 0.95502 -1.6046 AVKFLMSRAK 0 12.9535 9.7156 0 0 0 0 0 0 0 0 8.71349 0 10.7511 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P1U1 ARP3B_HUMAN Actin-related protein 3B (ARP3-beta) (Actin-like protein 3B) (Actin-related protein ARP4) ACTR3B ARP11 ARP4 Homo sapiens (Human) cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; extracellular exosome [GO:0070062] actin binding [GO:0003779]; ATP binding [GO:0005524] 0.79983 0.23962 LSEELSGGR 0 0 0 0 0 0 8.94427 9.04327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P1V8 SAM15_HUMAN Sterile alpha motif domain-containing protein 15 (SAM domain-containing protein 15) SAMD15 C14orf174 FAM15A Homo sapiens (Human) 0.96941 -3.9841 ERVSEDDETQPEK 0 0 8.85888 0 0 0 0 0 0 0 0 0 8.57297 0 0 0 0 0 0 0 0 0 9.98741 0 0 0 0 Q9P1W3 CSC1_HUMAN Calcium permeable stress-gated cation channel 1 (Transmembrane protein 63C) TMEM63C C14orf171 CSC1 Homo sapiens (Human) glomerular filtration [GO:0003094]; monoatomic cation transport [GO:0006812] plasma membrane [GO:0005886] calcium activated cation channel activity [GO:0005227]; osmolarity-sensing monoatomic cation channel activity [GO:1990760] 0.96733 -2.8211 IHPCARLCFCK 0 0 0 0 0 0 11.2095 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P1W8 SIRPG_HUMAN Signal-regulatory protein gamma (SIRP-gamma) (CD172 antigen-like family member B) (Signal-regulatory protein beta-2) (SIRP-b2) (SIRP-beta-2) (CD antigen CD172g) SIRPG SIRPB2 Homo sapiens (Human) cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; intracellular signal transduction [GO:0035556]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of phagocytosis [GO:0050766]; positive regulation of T cell activation [GO:0050870] membrane [GO:0016020]; plasma membrane [GO:0005886] 0.71663 0.3651 ETASTLTENKDGTYNWTSWFLVNISDQR 0 0 0 0 0 0 12.5478 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P1Y5 CAMP3_HUMAN Calmodulin-regulated spectrin-associated protein 3 (Protein Nezha) CAMSAP3 KIAA1543 Homo sapiens (Human) cilium movement [GO:0003341]; DNA replication checkpoint signaling [GO:0000076]; embryo development ending in birth or egg hatching [GO:0009792]; epithelial cell-cell adhesion [GO:0090136]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; in utero embryonic development [GO:0001701]; microtubule anchoring [GO:0034453]; microtubule cytoskeleton organization [GO:0000226]; neuron projection development [GO:0031175]; protein transport along microtubule [GO:0098840]; regulation of cell migration [GO:0030334]; regulation of focal adhesion assembly [GO:0051893]; regulation of Golgi organization [GO:1903358]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of microtubule polymerization [GO:0031113]; regulation of organelle organization [GO:0033043]; replication fork arrest [GO:0043111]; zonula adherens maintenance [GO:0045218] axoneme [GO:0005930]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; microtubule minus-end [GO:0036449]; motile cilium [GO:0031514]; replication fork protection complex [GO:0031298]; zonula adherens [GO:0005915] actin filament binding [GO:0051015]; calmodulin binding [GO:0005516]; DNA binding [GO:0003677]; microtubule minus-end binding [GO:0051011]; spectrin binding [GO:0030507] 0.28082 0.82935 AVTFSPDLGPVPHEGLGEYNR 0 0 0 0 0 0 12.8837 0 0 0 0 12.2024 0 0 0 0 0 0 0 0 9.67518 0 0 0 0 0 0 Q9P1Y6 PHRF1_HUMAN PHD and RING finger domain-containing protein 1 PHRF1 KIAA1542 Homo sapiens (Human) mRNA processing [GO:0006397]; protein ubiquitination [GO:0016567]; transcription by RNA polymerase II [GO:0006366] membrane [GO:0016020] metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; RNA polymerase binding [GO:0070063] 0.88508 -0.19575 GPWGHSR 0 0 0 0 0 0 0 0 0 0 14.1277 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P1Z0 ZBTB4_HUMAN Zinc finger and BTB domain-containing protein 4 (KAISO-like zinc finger protein 1) (KAISO-L1) ZBTB4 KIAA1538 Homo sapiens (Human) DNA damage response [GO:0006974]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] chromosome [GO:0005694]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; methyl-CpG binding [GO:0008327]; methyl-CpNpG binding [GO:0010428]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]" 0.96238 -2.4734 GEGERAGVER 0 0 0 0 0 9.56609 0 0 0 11.3687 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P1Z2 CACO1_HUMAN Calcium-binding and coiled-coil domain-containing protein 1 (Calphoglin) (Coiled-coil coactivator protein) (Sarcoma antigen NY-SAR-3) CALCOCO1 KIAA1536 PP13275 UNQ2436/PRO4996 Homo sapiens (Human) intracellular steroid hormone receptor signaling pathway [GO:0030518]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055] chromatin [GO:0000785]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634] beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; metal ion binding [GO:0046872]; nuclear receptor coactivator activity [GO:0030374]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription cis-regulatory region binding [GO:0000976]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712] 0.92248 -0.94488 LPPYGLCER 0 0 0 0 0 0 0 9.50682 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3099 0 0 10.9385 0 0 Q9P1Z3 HCN3_HUMAN Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 HCN3 KIAA1535 Homo sapiens (Human) cellular response to cAMP [GO:0071320]; cellular response to dopamine [GO:1903351]; potassium ion transmembrane transport [GO:0071805]; regulation of cation channel activity [GO:2001257]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of membrane depolarization [GO:0003254]; regulation of membrane potential [GO:0042391]; regulation of SA node cell action potential [GO:0098907]; response to cisplatin [GO:0072718]; sodium ion transmembrane transport [GO:0035725] axon [GO:0030424]; cone cell pedicle [GO:0044316]; dendrite [GO:0030425]; HCN channel complex [GO:0098855]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886] cAMP binding [GO:0030552]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated sodium channel activity [GO:0005248] 0.91735 -0.85286 ATGDGSPGRK 13.5939 11.2834 0 0 0 0 10.5385 0 11.1419 11.155 11.377 0 0 0 0 10.4414 0 10.2352 0 8.52058 0 0 0 0 0 7.74187 9.1145 Q9P1Z9 CC180_HUMAN Coiled-coil domain-containing protein 180 CCDC180 C9orf174 KIAA1529 Homo sapiens (Human) extracellular exosome [GO:0070062] 0.96765 -2.9668 CQPENSGKK 0 0 10.3396 8.23021 0 0 0 0 0 0 0 0 0 11.4169 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P202 WHRN_HUMAN Whirlin (Autosomal recessive deafness type 31 protein) WHRN DFNB31 KIAA1526 Homo sapiens (Human) auditory receptor cell stereocilium organization [GO:0060088]; cerebellar Purkinje cell layer formation [GO:0021694]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; inner ear receptor cell differentiation [GO:0060113]; inner ear receptor cell stereocilium organization [GO:0060122]; paranodal junction maintenance [GO:1990227]; positive regulation of gene expression [GO:0010628]; retina homeostasis [GO:0001895]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605] actin filament [GO:0005884]; ciliary basal body [GO:0036064]; cilium [GO:0005929]; cytoplasm [GO:0005737]; growth cone [GO:0030426]; periciliary membrane compartment [GO:1990075]; photoreceptor connecting cilium [GO:0032391]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; stereocilia ankle link [GO:0002141]; stereocilia ankle link complex [GO:0002142]; stereocilium [GO:0032420]; stereocilium tip [GO:0032426]; synapse [GO:0045202]; USH2 complex [GO:1990696] identical protein binding [GO:0042802] 0.91436 -0.81818 TKDRDYIDFLVTEFNVML 0 0 0 0 0 9.47011 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P206 K1522_HUMAN Uncharacterized protein KIAA1522 KIAA1522 Homo sapiens (Human) cell differentiation [GO:0030154] 0.75982 0.29352 IPTVDGRPR 0 0 0 0 0 0 0 0 9.61886 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P209 CEP72_HUMAN Centrosomal protein of 72 kDa (Cep72) CEP72 KIAA1519 Homo sapiens (Human) centriole replication [GO:0007099]; gamma-tubulin complex localization [GO:0033566]; regulation of protein localization to centrosome [GO:1904779]; spindle organization [GO:0007051] centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytosol [GO:0005829] 0.42117 0.66935 AEVEQMHWSYQELK 0 0 0 0 0 9.15102 0 0 10.9115 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P212 PLCE1_HUMAN "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 (EC 3.1.4.11) (Pancreas-enriched phospholipase C) (Phosphoinositide phospholipase C-epsilon-1) (Phospholipase C-epsilon-1) (PLC-epsilon-1)" PLCE1 KIAA1516 PLCE PPLC Homo sapiens (Human) calcium-mediated signaling [GO:0019722]; cytoskeleton organization [GO:0007010]; diacylglycerol biosynthetic process [GO:0006651]; epidermal growth factor receptor signaling pathway [GO:0007173]; glomerulus development [GO:0032835]; heart development [GO:0007507]; inositol phosphate-mediated signaling [GO:0048016]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of MAPK cascade [GO:0043410]; Ras protein signal transduction [GO:0007265]; regulation of cell growth [GO:0001558]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; regulation of protein kinase activity [GO:0045859]; regulation of Ras protein signal transduction [GO:0046578]; regulation of smooth muscle contraction [GO:0006940]; release of sequestered calcium ion into cytosol [GO:0051209] cytosol [GO:0005829]; Golgi membrane [GO:0000139]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886] enzyme binding [GO:0019899]; guanyl-nucleotide exchange factor activity [GO:0005085]; metal ion binding [GO:0046872]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipase C activity [GO:0004629]; small GTPase binding [GO:0031267] 0.95896 -1.7768 AKMHKECR 0 0 0 10.582 0 0 0 0 0 11.6799 0 0 0 9.4103 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P217 ZSWM5_HUMAN Zinc finger SWIM domain-containing protein 5 ZSWIM5 KIAA1511 Homo sapiens (Human) Cul2-RING ubiquitin ligase complex [GO:0031462]; extracellular space [GO:0005615] zinc ion binding [GO:0008270] 0.967 -2.8256 FERIPEPVQRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.07954 0 9.85689 0 10.8705 0 0 Q9P218 COKA1_HUMAN Collagen alpha-1(XX) chain COL20A1 KIAA1510 Homo sapiens (Human) collagen trimer [GO:0005581]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615] 0.020882 1.6383 AALQEATFDPQEVRK 11.6258 8.62783 0 0 0 0 0 9.16463 0 10.4855 10.7591 10.3681 0 0 0 0 0 0 0 11.2904 0 0 0 0 10.358 8.49721 0 Q9P219 DAPLE_HUMAN Protein Daple (Coiled-coil domain-containing protein 88C) (Dvl-associating protein with a high frequency of leucine residues) (hDaple) (Hook-related protein 2) (HkRP2) CCDC88C DAPLE KIAA1509 Homo sapiens (Human) apical constriction [GO:0003383]; cytoplasmic microtubule organization [GO:0031122]; cytoskeleton-dependent intracellular transport [GO:0030705]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-canonical Wnt signaling pathway [GO:0035567]; protein destabilization [GO:0031648]; regulation of protein phosphorylation [GO:0001932]; small GTPase mediated signal transduction [GO:0007264]; stress-activated protein kinase signaling cascade [GO:0031098] anchoring junction [GO:0070161]; cell junction [GO:0030054]; centrosome [GO:0005813]; cytoplasm [GO:0005737] dynein light intermediate chain binding [GO:0051959]; frizzled binding [GO:0005109]; G-protein alpha-subunit binding [GO:0001965]; guanyl-nucleotide exchange factor activity [GO:0005085]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; PDZ domain binding [GO:0030165]; protein self-association [GO:0043621] 0.9694 -3.0272 AEKLERELQR 0 12.0112 10.5303 0 0 0 9.76832 0 10.3832 0 0 9.34899 0 10.3823 0 0 0 11.7744 0 0 0 0 0 0 0 0 0 Q9P225 DYH2_HUMAN Dynein axonemal heavy chain 2 (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2) (Dynein heavy chain domain-containing protein 3) DNAH2 DNAHC2 DNHD3 KIAA1503 Homo sapiens (Human) cilium-dependent cell motility [GO:0060285]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] axonemal dynein complex [GO:0005858]; axoneme [GO:0005930]; dynein complex [GO:0030286]; inner dynein arm [GO:0036156]; microtubule [GO:0005874]; motile cilium [GO:0031514]; sperm flagellum [GO:0036126] ATP binding [GO:0005524]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; microtubule motor activity [GO:0003777]; minus-end-directed microtubule motor activity [GO:0008569] 0.96911 -7.0984 AGGQTREEK 9.6746 0 11.1892 0 0 0 9.86785 10.5191 10.5976 0 9.51481 0 10.9654 9.11444 10.3033 10.1097 10.5773 11.4637 0 10.7026 0 9.00672 10.8112 0 11.669 8.38141 0 Q9P227 RHG23_HUMAN Rho GTPase-activating protein 23 (Rho-type GTPase-activating protein 23) ARHGAP23 KIAA1501 Homo sapiens (Human) regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] cytosol [GO:0005829]; extracellular exosome [GO:0070062] GTPase activator activity [GO:0005096] 0.96963 -5.0707 DDMLGWIRAIR 12.3184 0 8.43813 0 0 10.8627 0 8.9751 11.2597 0 9.71622 0 10.3661 10.7152 0 8.65807 0 0 0 0 0 0 0 0 0 0 9.6905 Q9P232 CNTN3_HUMAN Contactin-3 (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein) CNTN3 KIAA1496 PANG Homo sapiens (Human) cell adhesion [GO:0007155] extracellular region [GO:0005576]; plasma membrane [GO:0005886] 0.92375 -1.0167 EPSNSIFPVGSEDKKITLHCEAR 0 0 0 0 10.7267 0 0 0 0 0 0 0 0 0 0 0 11.3467 0 0 0 0 0 0 0 0 10.3522 0 Q9P241 AT10D_HUMAN Phospholipid-transporting ATPase VD (EC 7.6.2.1) (ATPase class V type 10D) (P4-ATPase flippase complex alpha subunit ATP10D) ATP10D ATPVD KIAA1487 Homo sapiens (Human) monoatomic cation transport [GO:0006812]; monoatomic ion transmembrane transport [GO:0034220]; phospholipid translocation [GO:0045332] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; phospholipid-translocating ATPase complex [GO:1990531]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled intramembrane lipid transporter activity [GO:0140326]; glycosylceramide flippase activity [GO:0140351]; magnesium ion binding [GO:0000287] 0.88436 -0.14903 FSGAYVNNR 0 0 0 0 0 0 0 0 0 0 9.18703 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P242 NYAP2_HUMAN Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2 NYAP2 KIAA1486 Homo sapiens (Human) neuron projection morphogenesis [GO:0048812]; phosphatidylinositol 3-kinase signaling [GO:0014065] 0.95559 -1.5956 NETNLAYLKEKNEK 0 0 9.05317 8.62333 0 0 8.54353 8.64829 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P243 ZFAT_HUMAN Zinc finger protein ZFAT (Zinc finger gene in AITD susceptibility region) (Zinc finger protein 406) ZFAT KIAA1485 ZFAT1 ZNF406 Homo sapiens (Human) hematopoietic progenitor cell differentiation [GO:0002244]; regulation of DNA-templated transcription [GO:0006355]; spongiotrophoblast layer development [GO:0060712] cytosol [GO:0005829]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.78423 0.25455 CPTDGCDYSTPDK 0 11.2386 10.4907 0 0 0 10.1567 9.73806 11.2894 0 9.94721 10.7292 8.69561 0 8.53045 9.17268 0 0 0 0 0 0 0 0 0 0 0 Q9P246 STIM2_HUMAN Stromal interaction molecule 2 STIM2 KIAA1482 Homo sapiens (Human) activation of store-operated calcium channel activity [GO:0032237]; intracellular calcium ion homeostasis [GO:0006874]; positive regulation of calcium ion transport [GO:0051928]; store-operated calcium entry [GO:0002115] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; plasma membrane [GO:0005886] calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; store-operated calcium channel activity [GO:0015279] 0.95942 -1.7074 AEKEFELR 0 0 0 0 0 0 0 0 0 0 13.3907 0 0 0 0 0 0 12.9137 0 0 0 0 0 0 0 0 0 Q9P253 VPS18_HUMAN Vacuolar protein sorting-associated protein 18 homolog (hVPS18) VPS18 KIAA1475 Homo sapiens (Human) autophagy [GO:0006914]; endosomal vesicle fusion [GO:0034058]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; lysosome organization [GO:0007040]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; organelle fusion [GO:0048284]; protein ubiquitination [GO:0016567]; regulation of SNARE complex assembly [GO:0035542]; regulation of synaptic vesicle exocytosis [GO:2000300]; vesicle docking involved in exocytosis [GO:0006904]; viral entry into host cell [GO:0046718] actin filament [GO:0005884]; AP-3 adaptor complex [GO:0030123]; autophagosome [GO:0005776]; clathrin-coated vesicle [GO:0030136]; CORVET complex [GO:0033263]; early endosome [GO:0005769]; endosome [GO:0005768]; endosome membrane [GO:0010008]; glutamatergic synapse [GO:0098978]; HOPS complex [GO:0030897]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; presynapse [GO:0098793] actin binding [GO:0003779]; metal ion binding [GO:0046872]; protein-macromolecule adaptor activity [GO:0030674]; syntaxin binding [GO:0019905]; ubiquitin protein ligase activity [GO:0061630] 0.96221 -2.0323 EADFCFRQRR 0 0 0 0 0 0 0 0 9.65476 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.489 0 10.2963 Q9P255 ZN492_HUMAN Zinc finger protein 492 (Zinc finger protein 115) ZNF492 KIAA1473 ZNF115 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.91563 -0.80565 ECEKSFCMLSHLAQHK 0 0 0 0 0 0 0 9.26847 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P258 RCC2_HUMAN Protein RCC2 (RCC1-like protein TD-60) (Telophase disk protein of 60 kDa) RCC2 KIAA1470 TD60 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; cell cycle [GO:0007049]; cell division [GO:0051301]; chromosome passenger complex localization to kinetochore [GO:0072356]; establishment of protein localization [GO:0045184]; focal adhesion assembly [GO:0048041]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of GTPase activity [GO:0034260]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; positive regulation of attachment of spindle microtubules to kinetochore [GO:0051987]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; regulation of cell migration [GO:0030334]; regulation of fibroblast migration [GO:0010762]; regulation of ruffle assembly [GO:1900027] "chromosome, centromeric core domain [GO:0034506]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; microtubule [GO:0005874]; midbody [GO:0030496]; mitotic spindle midzone [GO:1990023]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]" guanyl-nucleotide exchange factor activity [GO:0005085]; microtubule binding [GO:0008017]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; small GTPase binding [GO:0031267] 0.95332 -1.5004 DESETEKEK 0 10.1751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P260 RELCH_HUMAN "RAB11-binding protein RELCH (LisH domain and HEAT repeat-containing protein KIAA1468) (RAB11 binding and LisH domain, coiled-coil and HEAT repeat-containing) (RAB11-binding protein containing LisH, coiled-coil, and HEAT repeats)" RELCH KIAA1468 Homo sapiens (Human) intracellular cholesterol transport [GO:0032367] recycling endosome [GO:0055037]; trans-Golgi network [GO:0005802] 0.97007 -5.1553 IADSEKSVMLMLGR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.39418 0 0 0 0 0 0 0 0 9.01795 0 0 8.93387 0 Q9P265 DIP2B_HUMAN Disco-interacting protein 2 homolog B (DIP2 homolog B) DIP2B KIAA1463 Homo sapiens (Human) negative regulation of axon extension [GO:0030517]; nervous system development [GO:0007399]; positive regulation of peptidyl-lysine acetylation [GO:2000758] axon [GO:0030424]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; perikaryon [GO:0043204] alpha-tubulin binding [GO:0043014] 0.11722 1.1191 AQATPDHVLFMLLNAK 9.59419 9.36715 9.49133 0 0 0 0 8.84784 0 11.8655 11.8694 0 0 0 0 9.70996 0 0 9.15881 0 9.11538 0 0 0 0 11.7821 0 Q9P266 JCAD_HUMAN Junctional cadherin 5-associated protein (Junctional protein associated with coronary artery disease) (JCAD) JCAD KIAA1462 Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748] adherens junction [GO:0005912]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587] 0.96756 -2.7884 LASPPRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.27733 0 0 0 Q9P267 MBD5_HUMAN Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5) MBD5 KIAA1461 Homo sapiens (Human) glucose homeostasis [GO:0042593]; nervous system development [GO:0007399]; positive regulation of growth hormone receptor signaling pathway [GO:0060399]; regulation of behavior [GO:0050795]; regulation of multicellular organism growth [GO:0040014] chromocenter [GO:0010369]; chromosome [GO:0005694]; extracellular exosome [GO:0070062]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682] 0.82231 0.21724 CAHINGNRPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.80487 0 0 0 0 0 0 0 0 0 0 Q9P273 TEN3_HUMAN Teneurin-3 (Ten-3) (Protein Odd Oz/ten-m homolog 3) (Tenascin-M3) (Ten-m3) (Teneurin transmembrane protein 3) TENM3 KIAA1455 ODZ3 TNM3 Homo sapiens (Human) camera-type eye morphogenesis [GO:0048593]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron development [GO:0048666]; positive regulation of neuron projection development [GO:0010976]; regulation of homophilic cell adhesion [GO:1903385]; signal transduction [GO:0007165] axon [GO:0030424]; membrane [GO:0016020]; neuron projection [GO:0043005]; plasma membrane [GO:0005886] cell adhesion molecule binding [GO:0050839]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803] 0.8772 -0.0060448 AVEATLMSPKGMAVDK 0 0 0 14.058 0 0 0 0 0 10.4608 15.0927 0 0 0 0 0 0 0 0 0 0 10.0736 0 10.0161 0 0 9.83648 Q9P275 UBP36_HUMAN Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.4.19.12) (Deubiquitinating enzyme 36) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) USP36 KIAA1453 Homo sapiens (Human) chromatin organization [GO:0006325]; negative regulation of macroautophagy [GO:0016242]; nucleolus organization [GO:0007000]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of apoptotic process [GO:0042981]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of protein stability [GO:0031647]; regulation of rRNA processing [GO:2000232]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] cysteine-type deubiquitinase activity [GO:0004843]; cysteine-type endopeptidase activity [GO:0004197]; K48-linked deubiquitinase activity [GO:1990380]; RNA binding [GO:0003723] 0.96884 -4.2005 AVEEDGHLK 0 0 0 0 0 0 0 0 0 0 11.0293 0 0 0 0 0 0 0 0 0 11.7821 0 0 0 0 0 0 Q9P281 BAHC1_HUMAN BAH and coiled-coil domain-containing protein 1 (Bromo adjacent homology domain-containing protein 2) (BAH domain-containing protein 2) BAHCC1 BAHD2 KIAA1447 Homo sapiens (Human) chromatin binding [GO:0003682] 0.9559 -1.5503 AEGKGER 0 0 0 0 8.87295 0 0 0 8.90331 0 0 0 0 0 9.24263 0 9.21624 0 0 0 9.07007 11.7541 0 0 0 0 0 Q9P289 STK26_HUMAN Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian STE20-like protein kinase 4) (MST-4) (STE20-like kinase MST4) (Serine/threonine-protein kinase MASK) STK26 MASK MST4 Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to starvation [GO:0009267]; microvillus assembly [GO:0030033]; negative regulation of cell migration [GO:0030336]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; response to hydrogen peroxide [GO:0042542]; stress-activated protein kinase signaling cascade [GO:0031098] apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle [GO:0005798]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; vesicle membrane [GO:0012506] ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.84407 0.15187 CSADESP 0 0 0 0 0 9.15947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0623 0 Q9P291 ARMX1_HUMAN Armadillo repeat-containing X-linked protein 1 (ARM protein lost in epithelial cancers on chromosome X 1) (Protein ALEX1) ARMCX1 ALEX1 AD032 Homo sapiens (Human) hematopoietic stem cell homeostasis [GO:0061484] mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739] 0.91504 -0.78045 AHSGSHSGGGLEAKAK 0 0 0 0 0 0 0 0 0 0 10.4733 0 0 0 0 0 8.37012 0 0 0 0 0 0 0 0 0 0 Q9P298 HIG1B_HUMAN HIG1 domain family member 1B (Protein CLST 11240) HIGD1B Homo sapiens (Human) mitochondrial respirasome assembly [GO:0097250] membrane [GO:0016020]; mitochondrion [GO:0005739] 0.8487 0.17129 WWVPPDDEDCVSEK 0 0 0 10.144 10.1261 9.30415 0 0 0 0 0 11.5289 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P2B2 FPRP_HUMAN Prostaglandin F2 receptor negative regulator (CD9 partner 1) (CD9P-1) (Glu-Trp-Ile EWI motif-containing protein F) (EWI-F) (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD antigen CD315) PTGFRN CD9P1 EWIF FPRP KIAA1436 Homo sapiens (Human) lipid droplet organization [GO:0034389]; myoblast fusion involved in skeletal muscle regeneration [GO:0014905] cell surface [GO:0009986]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794] 0.8613 0.094533 EHTDTFNFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.7578 0 0 0 0 8.85801 0 0 9.41806 0 10.3477 Q9P2B4 CT2NL_HUMAN CTTNBP2 N-terminal-like protein CTTNBP2NL KIAA1433 Homo sapiens (Human) negative regulation of transmembrane transport [GO:0034763]; negative regulation of transporter activity [GO:0032410]; protein dephosphorylation [GO:0006470] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; lamellipodium [GO:0030027] protein phosphatase 2A binding [GO:0051721] 0.21791 0.89407 AAEEGQK 0 12.3005 0 0 0 0 0 0 0 8.7735 8.62425 0 0 0 0 10.9558 0 0 10.1784 0 0 0 9.55491 10.6838 0 10.8595 10.6811 Q9P2B7 CFA97_HUMAN Cilia- and flagella-associated protein 97 CFAP97 KIAA1430 Homo sapiens (Human) spermatogenesis [GO:0007283] 0.96749 -2.9833 LYHSALNR 0 0 0 0 0 0 0 10.7368 0 0 0 0 0 0 0 0 0 0 0 9.12228 0 0 0 0 0 0 9.68541 Q9P2C4 TM181_HUMAN Transmembrane protein 181 TMEM181 GPR178 KIAA1423 Homo sapiens (Human) membrane [GO:0016020] toxic substance binding [GO:0015643] 0.78914 0.25122 CLTFYLPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.83966 0 0 0 0 0 0 0 0 0 0 Q9P2D0 IBTK_HUMAN Inhibitor of Bruton tyrosine kinase (IBtk) IBTK BTKI KIAA1417 Homo sapiens (Human) negative regulation of protein phosphorylation [GO:0001933]; release of sequestered calcium ion into cytosol [GO:0051209] cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoplasm [GO:0005654] protein kinase binding [GO:0019901]; protein tyrosine kinase inhibitor activity [GO:0030292] 0.96929 -4.7994 KVLVSGGHMEYK 0 0 0 0 0 0 0 0 11.7226 0 0 9.47452 11.9094 0 0 11.1856 0 0 11.6765 0 0 0 0 0 0 0 0 Q9P2D1 CHD7_HUMAN Chromodomain-helicase-DNA-binding protein 7 (CHD-7) (EC 3.6.4.12) (ATP-dependent helicase CHD7) CHD7 KIAA1416 Homo sapiens (Human) adult heart development [GO:0007512]; adult walking behavior [GO:0007628]; aorta morphogenesis [GO:0035909]; atrioventricular canal development [GO:0036302]; blood circulation [GO:0008015]; blood vessel remodeling [GO:0001974]; cardiac septum morphogenesis [GO:0060411]; central nervous system development [GO:0007417]; chordate embryonic development [GO:0043009]; chromatin remodeling [GO:0006338]; cognition [GO:0050890]; cranial nerve development [GO:0021545]; embryonic hindlimb morphogenesis [GO:0035116]; epithelium development [GO:0060429]; face development [GO:0060324]; female genitalia development [GO:0030540]; genitalia development [GO:0048806]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; innervation [GO:0060384]; limb development [GO:0060173]; nose development [GO:0043584]; olfactory behavior [GO:0042048]; olfactory bulb development [GO:0021772]; olfactory nerve development [GO:0021553]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of growth hormone secretion [GO:0060123]; regulation of neurogenesis [GO:0050767]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; response to bacterium [GO:0009617]; retina development in camera-type eye [GO:0060041]; right ventricular compact myocardium morphogenesis [GO:0003226]; rRNA processing [GO:0006364]; secondary palate development [GO:0062009]; semicircular canal morphogenesis [GO:0048752]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]; T cell differentiation [GO:0030217]; transcription by RNA polymerase II [GO:0006366]; ventricular trabecula myocardium morphogenesis [GO:0003222] chromatin [GO:0000785]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent chromatin remodeler activity [GO:0140658]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; helicase activity [GO:0004386]; histone binding [GO:0042393]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.92033 -0.91835 AELDIDALNGR 10.0498 9.78789 9.74345 0 0 11.8586 9.58382 0 0 0 10.8816 12.1092 10.1483 10.7621 0 10.768 0 12.2625 11.2021 10.3255 10.2596 9.1754 0 11.6671 11.103 12.0437 12.3776 Q9P2D3 HTR5B_HUMAN HEAT repeat-containing protein 5B HEATR5B KIAA1414 p200 p200a Homo sapiens (Human) "endocytosis [GO:0006897]; protein localization [GO:0008104]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]" clathrin-coated vesicle [GO:0030136]; cytosol [GO:0005829]; endocytic vesicle [GO:0030139]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nuclear speck [GO:0016607]; perinuclear region of cytoplasm [GO:0048471] 0.97015 -4.3237 LAAVACVGAFYEKMGR 10.1509 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2979 9.68354 0 Q9P2D6 F135A_HUMAN Protein FAM135A FAM135A KIAA1411 Homo sapiens (Human) cellular lipid metabolic process [GO:0044255] 0.96314 -2.1931 IEMCKTALKDK 0 11.3506 0 0 0 0 0 0 0 0 0 10.1685 0 0 0 11.1807 0 0 0 0 8.93469 0 0 0 0 0 0 Q9P2D7 DYH1_HUMAN Dynein axonemal heavy chain 1 (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1) (Heat shock regulated protein 1) (HSRF-1) (hDHC7) DNAH1 DHC7 DNAHC1 KIAA1410 Homo sapiens (Human) cilium movement [GO:0003341]; cilium-dependent cell motility [GO:0060285]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; flagellated sperm motility [GO:0030317]; inner dynein arm assembly [GO:0036159]; sperm axoneme assembly [GO:0007288] axonemal dynein complex [GO:0005858]; axoneme [GO:0005930]; extracellular region [GO:0005576]; inner dynein arm [GO:0036156]; microtubule [GO:0005874]; sperm flagellum [GO:0036126] ATP binding [GO:0005524]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; microtubule motor activity [GO:0003777]; minus-end-directed microtubule motor activity [GO:0008569] 0.97024 -5.1799 AIRDVNVPK 0 9.13271 0 0 0 0 0 10.9261 0 0 0 11.3663 0 11.9401 0 0 0 0 0 0 11.7821 9.26179 9.33689 0 0 0 11.3663 Q9P2D8 UNC79_HUMAN Protein unc-79 homolog UNC79 KIAA1409 Homo sapiens (Human) plasma membrane [GO:0005886] 0.92597 -1.182 ILCLHGECLYIAR 0 0 0 0 0 0 0 8.55812 0 0 0 0 0 10.2205 0 10.4217 0 0 0 0 9.24039 0 0 0 0 0 0 Q9P2E2 KIF17_HUMAN Kinesin-like protein KIF17 (KIF3-related motor protein) KIF17 KIAA1405 KIF3X Homo sapiens (Human) anterograde dendritic transport of neurotransmitter receptor complex [GO:0098971]; cell projection organization [GO:0030030]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] axoneme [GO:0005930]; ciliary basal body [GO:0036064]; cilium [GO:0005929]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; kinesin complex [GO:0005871]; microtubule [GO:0005874]; neuron projection [GO:0043005]; periciliary membrane compartment [GO:1990075]; photoreceptor connecting cilium [GO:0032391]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; microtubule binding [GO:0008017]; plus-end-directed microtubule motor activity [GO:0008574] 0.96804 -2.8741 INEDPKDALLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0459 0 0 0 0 0 0 0 0 0 8.45224 0 Q9P2E3 ZNFX1_HUMAN NFX1-type zinc finger-containing protein 1 ZNFX1 KIAA1404 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; small ncRNA-mediated heterochromatin formation [GO:0031048] cytoplasmic stress granule [GO:0010494]; mitochondrial outer membrane [GO:0005741]; nuclear RNA-directed RNA polymerase complex [GO:0031380] helicase activity [GO:0004386]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270] 0.95972 -1.7457 CQEPCIGECPPCQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.371 9.42748 0 0 10.0537 0 9.70004 0 0 0 0 0 Q9P2E5 CHPF2_HUMAN Chondroitin sulfate glucuronyltransferase (EC 2.4.1.226) (CSGlcA-T) (Chondroitin glucuronyltransferase) (Chondroitin polymerizing factor 2) (ChPF-2) (Chondroitin synthase 3) (ChSy-3) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase) CHPF2 CHSY3 CSGLCAT KIAA1402 UNQ299/PRO339 Homo sapiens (Human) chondroitin sulfate biosynthetic process [GO:0030206] Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; membrane [GO:0016020] glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity [GO:0047238]; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity [GO:0050510] 0.88364 -0.279 ARLDQSDEDFKPR 0 12.2876 0 0 0 0 0 0 0 0 9.38651 0 0 0 10.598 10.2778 0 0 0 0 0 0 0 0 0 0 0 Q9P2E9 RRBP1_HUMAN Ribosome-binding protein 1 (180 kDa ribosome receptor homolog) (RRp) (ES/130-related protein) (Ribosome receptor protein) RRBP1 KIAA1398 Homo sapiens (Human) osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; translation [GO:0006412] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; ribosome [GO:0005840] RNA binding [GO:0003723]; signaling receptor activity [GO:0038023] 0 6.8224 AAAGEAK 0 0 0 0 0 9.23204 0 0 9.51562 0 0 0 0 0 0 0 0 0 10.9524 9.92166 10.292 0 0 0 8.79494 0 0 Q9P2F5 STOX2_HUMAN Storkhead-box protein 2 STOX2 KIAA1392 Homo sapiens (Human) embryo development ending in birth or egg hatching [GO:0009792]; maternal placenta development [GO:0001893]; regulation of transcription by RNA polymerase II [GO:0006357] cytoplasm [GO:0005737]; nucleus [GO:0005634] RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977] 0.96934 -4.4281 EKERDLQR 0 0 0 0 0 8.9861 0 0 0 0 0 0 0 0 0 0 0 0 9.82626 8.74406 0 0 9.88425 0 0 0 0 Q9P2F6 RHG20_HUMAN Rho GTPase-activating protein 20 (Rho-type GTPase-activating protein 20) ARHGAP20 KIAA1391 Homo sapiens (Human) regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] cytosol [GO:0005829] GTPase activator activity [GO:0005096] 0.96118 -2.0033 AKAARPEEEK 0 10.4313 0 0 0 0 0 9.03147 0 0 0 0 10.2022 0 0 10.5088 0 10.1753 0 0 0 0 0 10.5032 0 0 0 Q9P2F8 SI1L2_HUMAN Signal-induced proliferation-associated 1-like protein 2 (SIPA1-like protein 2) SIPA1L2 KIAA1389 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056] cytoplasm [GO:0005737] GTPase activator activity [GO:0005096] 0.97008 -5.358 DSKNVVFNCSCR 9.63012 0 0 0 0 0 10.4867 10.7124 0 0 0 10.0962 11.6457 0 8.65198 0 0 12.0143 0 0 0 10.9347 0 0 0 12.3067 0 Q9P2G1 AKIB1_HUMAN Ankyrin repeat and IBR domain-containing protein 1 (EC 2.3.2.31) ANKIB1 KIAA1386 Homo sapiens (Human) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737]; ubiquitin ligase complex [GO:0000151] metal ion binding [GO:0046872]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630] 0.89863 -0.62125 FMHYYTR 0 10.3417 0 0 0 0 10.9307 0 0 0 11.4515 11.5902 0 11.1369 0 0 11.4638 0 0 0 0 10.729 10.4802 10.4996 0 12.7449 11.0865 Q9P2G4 MAP10_HUMAN Microtubule-associated protein 10 (Microtubule regulator of 120 KDa) MAP10 KIAA1383 MTR120 Homo sapiens (Human) cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; mitotic spindle midzone assembly [GO:0051256]; positive regulation of cytokinesis [GO:0032467]; regulation of microtubule-based process [GO:0032886] centrosome [GO:0005813]; cytoplasmic microtubule [GO:0005881]; midbody [GO:0030496]; mitotic spindle midzone [GO:1990023]; mitotic spindle pole [GO:0097431] microtubule binding [GO:0008017] 0.87191 0.060392 QISGVFDEPSTSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.87318 0 0 Q9P2G9 KLHL8_HUMAN Kelch-like protein 8 KLHL8 KIAA1378 Homo sapiens (Human) protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] Cul3-RING ubiquitin ligase complex [GO:0031463]; nucleoplasm [GO:0005654] 0.11754 1.102 ASMNTKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.14728 8.96576 0 9.14149 0 0 7.97968 8.26336 0 9.39528 0 Q9P2H0 CE126_HUMAN Centrosomal protein of 126 kDa CEP126 KIAA1377 Homo sapiens (Human) cilium assembly [GO:0060271]; cytoplasmic microtubule organization [GO:0031122]; mitotic spindle organization [GO:0007052]; non-motile cilium assembly [GO:1905515] centrosome [GO:0005813]; ciliary base [GO:0097546]; cytoplasm [GO:0005737]; midbody [GO:0030496] 0.95989 -1.9401 AVSRKPVPPLEEALK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6862 0 0 0 0 9.79581 9.45413 9.544 9.42725 0 0 0 Q9P2H5 UBP35_HUMAN Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.4.19.12) (Deubiquitinating enzyme 35) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) USP35 KIAA1372 USP34 Homo sapiens (Human) protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] cytosol [GO:0005829]; nucleus [GO:0005634] cysteine-type deubiquitinase activity [GO:0004843]; cysteine-type endopeptidase activity [GO:0004197] 0.96469 -2.689 EEVGEEEESTR 0 0 0 0 9.90397 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.85894 0 0 0 0 Q9P2I0 CPSF2_HUMAN Cleavage and polyadenylation specificity factor subunit 2 (Cleavage and polyadenylation specificity factor 100 kDa subunit) (CPSF 100 kDa subunit) CPSF2 CPSF100 KIAA1367 Homo sapiens (Human) mRNA 3'-end processing by stem-loop binding and cleavage [GO:0006398]; mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789] glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleoplasm [GO:0005654]; postsynapse [GO:0098794] RNA binding [GO:0003723] 0.92416 -0.9495 FSQIVNLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.84477 0 Q9P2J2 TUTLA_HUMAN Protein turtle homolog A (Immunoglobulin superfamily member 9A) (IgSF9A) IGSF9 IGSF9A KIAA1355 NRT1 Homo sapiens (Human) axon guidance [GO:0007411]; dendrite development [GO:0016358]; dendrite self-avoidance [GO:0070593]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; regulation of synapse organization [GO:0050807] axon [GO:0030424]; dendrite [GO:0030425]; inhibitory synapse [GO:0060077]; plasma membrane [GO:0005886] cell-cell adhesion mediator activity [GO:0098632] 0.88374 -0.26037 EEFLAFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.05192 0 0 0 0 0 0 0 0 0 0 Q9P2J3 KLHL9_HUMAN Kelch-like protein 9 KLHL9 KIAA1354 Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; protein ubiquitination [GO:0016567]; regulation of cytokinesis [GO:0032465] Cul3-RING ubiquitin ligase complex [GO:0031463]; cytosol [GO:0005829]; midbody [GO:0030496] cullin family protein binding [GO:0097602] 0.96403 -2.4103 ELRMYDER 0 0 0 0 0 0 0 0 0 0 0 0 9.68222 10.4668 0 0 0 0 0 0 0 0 0 0 0 0 10.6931 Q9P2J5 SYLC_HUMAN "Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)" LARS1 KIAA1352 LARS Homo sapiens (Human) cellular response to amino acid starvation [GO:0034198]; cellular response to amino acid stimulus [GO:0071230]; cellular response to leucine [GO:0071233]; cellular response to leucine starvation [GO:1990253]; glutaminyl-tRNA aminoacylation [GO:0006425]; leucyl-tRNA aminoacylation [GO:0006429]; positive regulation of GTPase activity [GO:0043547]; positive regulation of TOR signaling [GO:0032008]; positive regulation of TORC1 signaling [GO:1904263]; regulation of cell size [GO:0008361]; tRNA aminoacylation for protein translation [GO:0006418] aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; lysosome [GO:0005764]; nuclear body [GO:0016604] aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]; GTPase activator activity [GO:0005096]; leucine-tRNA ligase activity [GO:0004823] 0.043197 1.4874 FDDPLLGPR 0 0 0 0 0 0 0 9.66913 0 0 0 0 0 0 0 0 0 0 0 0 10.9082 0 0 0 10.4179 0 0 Q9P2J8 ZN624_HUMAN Zinc finger protein 624 ZNF624 KIAA1349 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.89517 -0.51819 LQNNQENHLSQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.34096 9.66851 0 0 0 10.2004 0 Q9P2J9 PDP2_HUMAN "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial (PDP 2) (EC 3.1.3.43) (Pyruvate dehydrogenase phosphatase catalytic subunit 2) (PDPC 2)" PDP2 KIAA1348 Homo sapiens (Human) positive regulation of pyruvate dehydrogenase activity [GO:1904184]; protein dephosphorylation [GO:0006470] mitochondrial matrix [GO:0005759] [pyruvate dehydrogenase (lipoamide)] phosphatase activity [GO:0004741]; [pyruvate dehydrogenase (lipoamide)] phosphatase regulator activity [GO:0019909]; metal ion binding [GO:0046872]; protein serine/threonine phosphatase activity [GO:0004722] 0.78585 0.25497 LVVGHLAEADWHK 0 0 0 0 0 0 0 0 0 0 0 9.23967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P2K1 C2D2A_HUMAN Coiled-coil and C2 domain-containing protein 2A CC2D2A KIAA1345 Homo sapiens (Human) axoneme assembly [GO:0035082]; camera-type eye development [GO:0043010]; cilium assembly [GO:0060271]; determination of left/right symmetry [GO:0007368]; embryonic brain development [GO:1990403]; heart development [GO:0007507]; kidney development [GO:0001822]; motile cilium assembly [GO:0044458]; neural tube closure [GO:0001843]; non-motile cilium assembly [GO:1905515]; protein localization to ciliary transition zone [GO:1904491]; smoothened signaling pathway [GO:0007224] ciliary transition zone [GO:0035869]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; MKS complex [GO:0036038] 0.96793 -3.7362 ERNMILER 0 9.55411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.95672 0 0 0 0 0 0 9.30731 0 0 0 Q9P2K2 TXD16_HUMAN Thioredoxin domain-containing protein 16 TXNDC16 ERP90 KIAA1344 Homo sapiens (Human) endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062] 0.92462 -0.98599 GYVITGIYSEEDVLLLSTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.55344 0 0 9.03678 0 0 0 0 0 0 0 0 0 Q9P2K5 MYEF2_HUMAN Myelin expression factor 2 (MEF-2) (MyEF-2) (MST156) MYEF2 KIAA1341 Homo sapiens (Human) myotube differentiation [GO:0014902]; neuron differentiation [GO:0030182] nucleus [GO:0005634] DNA binding [GO:0003677]; mRNA binding [GO:0003729]; RNA binding [GO:0003723] 0.95407 -1.5136 ALETMNK 8.87104 10.2748 0 9.89853 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.56491 0 0 0 0 11.2761 0 11.4825 0 Q9P2K8 E2AK4_HUMAN eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 4) (GCN2-like protein) EIF2AK4 GCN2 KIAA1338 Homo sapiens (Human) adaptive immune response [GO:0002250]; cell cycle [GO:0007049]; cellular response to amino acid starvation [GO:0034198]; cellular response to cold [GO:0070417]; cellular response to leucine starvation [GO:1990253]; cellular response to UV [GO:0034644]; defense response to virus [GO:0051607]; DNA damage checkpoint signaling [GO:0000077]; eiF2alpha phosphorylation in response to endoplasmic reticulum stress [GO:0036492]; GCN2-mediated signaling [GO:0140469]; learning [GO:0007612]; long-term memory [GO:0007616]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of CREB transcription factor activity [GO:0032792]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of translational initiation [GO:0045947]; negative regulation of translational initiation in response to stress [GO:0032057]; neuron projection extension [GO:1990138]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of translational initiation in response to starvation [GO:0071264]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of feeding behavior [GO:0060259]; regulation of translational initiation [GO:0006446]; regulation of translational initiation by eIF2 alpha phosphorylation [GO:0010998]; T cell activation involved in immune response [GO:0002286]; viral translation [GO:0019081] cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; polysome [GO:0005844] ATP binding [GO:0005524]; eukaryotic translation initiation factor 2alpha kinase activity [GO:0004694]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; tRNA binding [GO:0000049] 0.96961 -3.168 CVCLDDKER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2936 10.6293 0 0 0 9.66048 0 0 0 0 0 0 Q9P2L0 WDR35_HUMAN WD repeat-containing protein 35 (Intraflagellar transport protein 121 homolog) WDR35 IFT121 KIAA1336 Homo sapiens (Human) cellular response to leukemia inhibitory factor [GO:1990830]; cilium assembly [GO:0060271]; intraciliary retrograde transport [GO:0035721]; intraciliary transport [GO:0042073]; protein localization to cilium [GO:0061512] axoneme [GO:0005930]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary tip [GO:0097542]; cilium [GO:0005929]; intraciliary transport particle A [GO:0030991] 0.56539 0.4994 ANYFFDAAKLMFK 0 0 0 0 0 0 0 12.162 0 0 0 0 0 0 0 0 0 0 0 10.6838 0 0 0 0 10.2564 0 0 Q9P2M4 TBC14_HUMAN TBC1 domain family member 14 TBC1D14 KIAA1322 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; autophagy [GO:0006914]; negative regulation of autophagy [GO:0010507]; recycling endosome to Golgi transport [GO:0071955]; regulation of autophagosome assembly [GO:2000785] autophagosome [GO:0005776]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; recycling endosome [GO:0055037] GTPase activator activity [GO:0005096]; protein kinase binding [GO:0019901] 0.92252 -1.102 APRLLSAPEYGPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.6818 0 0 0 0 0 0 0 0 0 Q9P2M7 CING_HUMAN Cingulin CGN KIAA1319 Homo sapiens (Human) microtubule cytoskeleton organization [GO:0000226] bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; myosin complex [GO:0016459]; plasma membrane [GO:0005886] actin binding [GO:0003779]; cadherin binding [GO:0045296]; microtubule binding [GO:0008017] 0.96861 -8.5715 ALEEEGKQR 0 10.8248 0 0 0 0 0 0 0 8.16093 8.80594 10.4033 8.76977 8.53146 8.64014 0 10.181 0 9.09608 0 0 0 10.3931 0 0 10.8402 0 Q9P2N4 ATS9_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAM-TS 9) (ADAM-TS9) (ADAMTS-9) (EC 3.4.24.-) ADAMTS9 KIAA1312 Homo sapiens (Human) aorta morphogenesis [GO:0035909]; endothelial cell-matrix adhesion [GO:0090673]; extracellular matrix organization [GO:0030198]; heart valve morphogenesis [GO:0003179]; melanocyte differentiation [GO:0030318]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of sprouting angiogenesis [GO:1903671]; positive regulation of melanocyte differentiation [GO:0045636]; protein transport [GO:0015031]; proteolysis [GO:0006508]; response to bacterium [GO:0009617]; ventricular cardiac muscle tissue development [GO:0003229]; vesicle-mediated transport [GO:0016192] cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231] metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270] 0.21746 0.88672 GVQQRHVGCQIGTHK 12.4791 12.1792 12.0037 10.457 10.5265 10.5215 12.2039 12.051 12.163 11.0756 11.6874 13.4458 10.6768 11.1474 11.0046 11.1195 11.7393 9.87117 9.00459 8.9448 0 0 0 9.702 0 0 0 Q9P2N5 RBM27_HUMAN RNA-binding protein 27 (RNA-binding motif protein 27) RBM27 KIAA1311 Homo sapiens (Human) mRNA processing [GO:0006397] cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA binding [GO:0003723] 0.96973 -3.5082 ELLDTELDLHK 0 0 0 0 0 0 0 0 0 0 12.4533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P2N6 KANL3_HUMAN KAT8 regulatory NSL complex subunit 3 (NSL complex protein NSL3) (Non-specific lethal 3 homolog) (Serum inhibited-related protein) (Testis development protein PRTD) KANSL3 KIAA1310 NSL3 PRTD SI1 Homo sapiens (Human) chromatin organization [GO:0006325]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of dosage compensation by inactivation of X chromosome [GO:1900095] histone acetyltransferase complex [GO:0000123]; intracellular membrane-bounded organelle [GO:0043231]; NSL complex [GO:0044545]; nucleoplasm [GO:0005654] 0.96854 -2.7671 ALQSDRLAR 0 0 0 0 0 16.1835 17.899 18.12 18.2163 0 12.2522 0 0 0 0 0 0 17.0888 13.7578 0 0 0 0 0 0 10.3492 0 Q9P2N7 KLH13_HUMAN Kelch-like protein 13 (BTB and kelch domain-containing protein 2) KLHL13 BKLHD2 KIAA1309 Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; protein ubiquitination [GO:0016567]; regulation of cytokinesis [GO:0032465] Cul3-RING ubiquitin ligase complex [GO:0031463]; cytosol [GO:0005829] cullin family protein binding [GO:0097602] 0.9553 -1.5522 ELRMYDEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.741 0 0 0 0 0 0 0 0 0 Q9P2P1 NYNRI_HUMAN Protein NYNRIN (NYN domain and retroviral integrase catalytic domain-containing protein) (Protein cousin of GIN1) NYNRIN CGIN1 KIAA1305 Homo sapiens (Human) "DNA integration [GO:0015074]; DNA repair [GO:0006281]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]" cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nucleus [GO:0005634] mRNA binding [GO:0003729]; RNA endonuclease activity [GO:0004521]; RNA-DNA hybrid ribonuclease activity [GO:0004523] 0.96395 -2.682 APAAPKVPVTPRVSR 0 8.63459 8.41384 8.83393 0 8.29925 0 8.90998 10.7703 11.9678 11.8199 10.3725 0 0 10.3036 11.4727 11.9178 10.6838 10.0178 10.3591 0 8.38076 0 11.0013 0 0 0 Q9P2P5 HECW2_HUMAN "E3 ubiquitin-protein ligase HECW2 (EC 2.3.2.26) (HECT, C2 and WW domain-containing protein 2) (HECT-type E3 ubiquitin transferase HECW2) (NEDD4-like E3 ubiquitin-protein ligase 2)" HECW2 KIAA1301 NEDL2 Homo sapiens (Human) negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; protein ubiquitination [GO:0016567]; regulation of dendrite morphogenesis [GO:0048814]; regulation of mitotic metaphase/anaphase transition [GO:0030071] cytoplasm [GO:0005737]; mitotic spindle [GO:0072686] ubiquitin protein ligase activity [GO:0061630] 0.92135 -0.93546 EYIERMVK 10.5851 0 0 0 0 0 10.4108 0 0 8.92615 0 10.8717 8.90011 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P2P6 STAR9_HUMAN StAR-related lipid transfer protein 9 (START domain-containing protein 9) (StARD9) STARD9 KIAA1300 Homo sapiens (Human) microtubule-based movement [GO:0007018]; spindle assembly [GO:0051225] centriole [GO:0005814]; cytoplasm [GO:0005737]; nucleus [GO:0005634] ATP binding [GO:0005524]; lipid binding [GO:0008289]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777] 0.96938 -6.4953 AIETLRRER 0 11.375 8.75532 0 0 0 9.00904 9.38741 0 10.497 11.8849 0 0 0 0 9.45732 9.56343 8.69181 0 0 8.75158 0 0 9.02411 10.3361 9.18678 0 Q9P2Q2 FRM4A_HUMAN FERM domain-containing protein 4A FRMD4A FRMD4 KIAA1294 Homo sapiens (Human) establishment of epithelial cell polarity [GO:0090162]; negative regulation of protein secretion [GO:0050709]; positive regulation of protein secretion [GO:0050714] adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856] protein-macromolecule adaptor activity [GO:0030674] 0.96205 -2.4612 LDEQKILPK 0 0 0 0 0 0 10.2403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P2R3 ANFY1_HUMAN Rabankyrin-5 (Rank-5) (Ankyrin repeat and FYVE domain-containing protein 1) (Ankyrin repeats hooked to a zinc finger motif) ANKFY1 ANKHZN KIAA1255 Homo sapiens (Human) "endocytosis [GO:0006897]; endosomal transport [GO:0016197]; endosomal vesicle fusion [GO:0034058]; Golgi to lysosome transport [GO:0090160]; positive regulation of pinocytosis [GO:0048549]; retrograde transport, endosome to Golgi [GO:0042147]" cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; macropinosome [GO:0044354]; membrane [GO:0016020] metal ion binding [GO:0046872]; phosphatidylinositol phosphate binding [GO:1901981]; small GTPase binding [GO:0031267] 0.96211 -2.6145 FQLQLLR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.33684 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P2R6 RERE_HUMAN Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein) RERE ARG ARP ATN1L KIAA0458 Homo sapiens (Human) branching morphogenesis of a nerve [GO:0048755]; cerebellar granule cell precursor proliferation [GO:0021930]; cerebellar Purkinje cell layer maturation [GO:0021691]; chromatin remodeling [GO:0006338]; dendrite morphogenesis [GO:0048813]; radial glia guided migration of Purkinje cell [GO:0021942] histone deacetylase complex [GO:0000118]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714] 0.96895 -3.3394 DIDQDNR 8.51159 0 8.34105 0 0 0 9.1605 8.99839 0 8.52775 0 0 0 0 0 0 10.8302 0 0 0 0 0 0 0 8.46033 0 0 Q9P2R7 SUCB1_HUMAN "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial (EC 6.2.1.5) (ATP-specific succinyl-CoA synthetase subunit beta) (A-SCS) (Succinyl-CoA synthetase beta-A chain) (SCS-betaA)" SUCLA2 Homo sapiens (Human) succinate metabolic process [GO:0006105]; succinyl-CoA catabolic process [GO:1901289]; succinyl-CoA metabolic process [GO:0006104]; succinyl-CoA pathway [GO:0006781]; tricarboxylic acid cycle [GO:0006099] extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; succinate-CoA ligase complex [GO:0042709]; succinate-CoA ligase complex (ADP-forming) [GO:0009361] ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; succinate-CoA ligase (ADP-forming) activity [GO:0004775] 0.59013 0.4528 IVFSPEEAK 0 0 0 0 0 0 9.31633 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P2S2 NRX2A_HUMAN Neurexin-2 (Neurexin II-alpha) (Neurexin-2-alpha) NRXN2 KIAA0921 Homo sapiens (Human) adult behavior [GO:0030534]; chemical synaptic transmission [GO:0007268]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; neurotransmitter secretion [GO:0007269]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; signal transduction [GO:0007165]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625] cell projection [GO:0042995]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991] calcium channel regulator activity [GO:0005246]; cell adhesion molecule binding [GO:0050839]; metal ion binding [GO:0046872]; neuroligin family protein binding [GO:0097109]; transmembrane signaling receptor activity [GO:0004888] 0.96111 -2.0084 EGDPKMK 0 0 9.17118 0 0 0 0 0 0 0 0 0 11.1266 8.86192 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P2S6 ANKY1_HUMAN Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc finger MYND domain-containing protein 13) ANKMY1 TSAL1 ZMYND13 Homo sapiens (Human) metal ion binding [GO:0046872] 0.90802 -0.73993 RSGFAPCGPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.24781 0 0 0 0 0 0 0 0 0 0 Q9P2T0 THEG_HUMAN Testicular haploid expressed gene protein (Cancer/testis antigen 56) (CT56) THEG Homo sapiens (Human) cell differentiation [GO:0030154]; chaperone-mediated protein complex assembly [GO:0051131]; spermatogenesis [GO:0007283] nucleus [GO:0005634] 0.36485 0.74481 RFYLEYYNNNR 0 0 0 0 0 0 0 0 0 0 0 9.56201 0 0 0 0 0 0 9.77353 0 0 0 0 0 0 0 0 Q9P2T1 GMPR2_HUMAN GMP reductase 2 (GMPR 2) (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 2) (Guanosine monophosphate reductase 2) GMPR2 Homo sapiens (Human) GMP metabolic process [GO:0046037]; purine nucleobase metabolic process [GO:0006144] cytosol [GO:0005829]; GMP reductase complex [GO:1902560] GMP reductase activity [GO:0003920]; metal ion binding [GO:0046872] 0.96666 -2.3535 DILGGIR 0 0 0 0 0 11.3237 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.8699 0 0 0 0 0 0 Q9P2V4 LRIT1_HUMAN "Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1 (Leucine-rich repeat-containing protein 21) (Photoreceptor-associated LRR superfamily protein) (Retina-specific protein PAL)" LRIT1 LRRC21 PAL Homo sapiens (Human) endoplasmic reticulum membrane [GO:0005789] 0.10701 1.138 AGPSEAR 0 0 0 0 8.98982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6318 0 0 0 0 0 Q9P2W1 HOP2_HUMAN Homologous-pairing protein 2 homolog (Nuclear receptor coactivator GT198) (PSMC3-interacting protein) (Proteasome 26S ATPase subunit 3-interacting protein) (Tat-binding protein 1-interacting protein) (TBP-1-interacting protein) PSMC3IP HOP2 TBPIP Homo sapiens (Human) homologous chromosome pairing at meiosis [GO:0007129]; meiotic joint molecule formation [GO:0000709]; meiotic strand invasion involved in reciprocal meiotic recombination [GO:0010774]; reciprocal meiotic recombination [GO:0007131] condensed nuclear chromosome [GO:0000794]; DNA recombinase auxiliary factor complex [GO:0120231]; nucleoplasm [GO:0005654] double-stranded DNA binding [GO:0003690]; nuclear receptor coactivator activity [GO:0030374]; recombinase activator activity [GO:0120230] 0.94138 -1.3144 AATNHVTPEEK 0 0 0 0 0 0 0 0 0 0 0 0 9.95411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9P2Y5 UVRAG_HUMAN UV radiation resistance-associated gene protein (p63) UVRAG Homo sapiens (Human) "autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; centrosome cycle [GO:0007098]; chromosome segregation [GO:0007059]; DNA repair [GO:0006281]; double-strand break repair via classical nonhomologous end joining [GO:0097680]; maintenance of Golgi location [GO:0051684]; multivesicular body sorting pathway [GO:0071985]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of autophagosome maturation [GO:1901098]; protein phosphorylation [GO:0006468]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of protein serine/threonine kinase activity [GO:0071900]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; SNARE complex assembly [GO:0035493]; spindle organization [GO:0007051]; viral entry into host cell [GO:0046718]" "autophagosome membrane [GO:0000421]; centrosome [GO:0005813]; chromosome, centromeric region [GO:0000775]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endosome [GO:0005768]; late endosome [GO:0005770]; lysosome [GO:0005764]; lytic vacuole [GO:0000323]; midbody [GO:0030496]; phagocytic vesicle [GO:0045335]; phosphatidylinositol 3-kinase complex, class III [GO:0035032]" SH3 domain binding [GO:0017124]; SNARE binding [GO:0000149] 0.87881 0.011485 QLLSELSYIYPIDLNEHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6468 0 0 0 0 0 0 0 Q9P2Z0 THA10_HUMAN THAP domain-containing protein 10 THAP10 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.93978 -1.3031 LLWDRFVRGCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9517 Q9UBB4 ATX10_HUMAN Ataxin-10 (Brain protein E46 homolog) (Spinocerebellar ataxia type 10 protein) ATXN10 SCA10 Homo sapiens (Human) cilium assembly [GO:0060271]; nervous system development [GO:0007399]; neuron projection development [GO:0031175] cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular space [GO:0005615]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] 0.956 -1.5503 LILKSTR 0 0 0 0 0 0 0 0 0 0 10.2027 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UBB5 MBD2_HUMAN Methyl-CpG-binding domain protein 2 (Demethylase) (DMTase) (Methyl-CpG-binding protein MBD2) MBD2 Homo sapiens (Human) aging [GO:0007568]; cellular response to organic cyclic compound [GO:0071407]; chromatin remodeling [GO:0006338]; DNA methylation-dependent heterochromatin formation [GO:0006346]; embryonic organ development [GO:0048568]; heart development [GO:0007507]; histone deacetylation [GO:0016575]; maternal behavior [GO:0042711]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of chromatin binding [GO:0035563]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of Wnt signaling pathway [GO:0030177]; protein-containing complex assembly [GO:0065003]; regulation of cell population proliferation [GO:0042127]; regulation of DNA methylation [GO:0044030]; response to estradiol [GO:0032355]; response to mechanical stimulus [GO:0009612]; response to nutrient levels [GO:0031667]; Wnt signaling pathway [GO:0016055] chromatin [GO:0000785]; cytosol [GO:0005829]; heterochromatin [GO:0000792]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NuRD complex [GO:0016581]; protein-containing complex [GO:0032991] C2H2 zinc finger domain binding [GO:0070742]; chromatin binding [GO:0003682]; methyl-CpG binding [GO:0008327]; molecular adaptor activity [GO:0060090]; mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; satellite DNA binding [GO:0003696]; siRNA binding [GO:0035197] 0.14261 1.0368 AADTEEMDIEMDSGDEA 8.64674 8.43488 0 0 0 0 0 8.37295 0 0 0 0 9.94303 8.5542 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UBB9 TFP11_HUMAN Tuftelin-interacting protein 11 (Septin and tuftelin-interacting protein 1) (STIP-1) TFIP11 STIP HSPC006 Homo sapiens (Human) "biomineral tissue development [GO:0031214]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of DNA ligase activity [GO:1904876]; negative regulation of double-strand break repair via nonhomologous end joining [GO:2001033]; negative regulation of protein binding [GO:0032091]; negative regulation of protein-containing complex assembly [GO:0031333]; protection from non-homologous end joining at telomere [GO:0031848]; RNA processing [GO:0006396]; spliceosomal complex disassembly [GO:0000390]" "catalytic step 2 spliceosome [GO:0071013]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U2-type post-mRNA release spliceosomal complex [GO:0071008]" nucleic acid binding [GO:0003676] 0.96367 -2.2471 GFAGGTK 0 0 0 0 0 0 0 0 9.45018 0 0 0 9.78483 9.36715 0 0 0 0 0 0 10.8584 9.73079 0 0 0 0 9.45685 Q9UBC1 IKBL1_HUMAN NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like protein) (I-kappa-B-like protein) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1) NFKBIL1 IKBL Homo sapiens (Human) cellular response to lipopolysaccharide [GO:0071222]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of tumor necrosis factor production [GO:0032720] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.84853 0.15778 SNPSPQVPEEEASTSVCRPK 0 0 0 0 0 0 0 0 0 9.34607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UBC2 EP15R_HUMAN Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) EPS15L1 EPS15R Homo sapiens (Human) endocytosis [GO:0006897]; endosomal transport [GO:0016197] clathrin coat of coated pit [GO:0030132]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886] cadherin binding [GO:0045296]; calcium ion binding [GO:0005509] 0.87074 0.033576 IWDLADPEGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.83359 0 Q9UBC3 DNM3B_HUMAN DNA (cytosine-5)-methyltransferase 3B (Dnmt3b) (EC 2.1.1.37) (DNA methyltransferase HsaIIIB) (DNA MTase HsaIIIB) (M.HsaIIIB) DNMT3B Homo sapiens (Human) C-5 methylation of cytosine [GO:0090116]; DNA methylation [GO:0006306]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of gene expression [GO:0010628] catalytic complex [GO:1902494]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates [GO:0051718]; DNA binding [GO:0003677]; DNA-methyltransferase activity [GO:0009008]; metal ion binding [GO:0046872]; transcription corepressor activity [GO:0003714]" 0.87019 0.040509 ELLLCSNTSCCR 11.3127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UBC9 SPRR3_HUMAN Small proline-rich protein 3 (22 kDa pancornulin) (Cornifin beta) (Esophagin) SPRR3 SPRC Homo sapiens (Human) epidermis development [GO:0008544]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; wound healing [GO:0042060] cornified envelope [GO:0001533]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; perinuclear region of cytoplasm [GO:0048471] structural molecule activity [GO:0005198] 0.7217 0.36384 VPEQGYTK 0 0 0 0 0 0 0 0 0 0 0 9.76845 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UBD0 HSFX1_HUMAN "Heat shock transcription factor, X-linked" HSFX1 LW-1; HSFX2 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.93043 -1.247 SLSMARCEERNSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.66945 0 0 0 0 0 0 0 0 0 0 Q9UBD3 XCL2_HUMAN Cytokine SCM-1 beta (C motif chemokine 2) (XC chemokine ligand 2) XCL2 SCYC2 Homo sapiens (Human) blood circulation [GO:0008015]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to type II interferon [GO:0071346]; chemokine-mediated signaling pathway [GO:0070098]; eosinophil chemotaxis [GO:0048245]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; lymphocyte chemotaxis [GO:0048247]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of T cell chemotaxis [GO:0010820]; signal transduction [GO:0007165] extracellular region [GO:0005576]; extracellular space [GO:0005615] CCR chemokine receptor binding [GO:0048020]; chemokine activity [GO:0008009] 0.96315 -2.6614 GLKVCADPQATWVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2922 0 Q9UBD5 ORC3_HUMAN Origin recognition complex subunit 3 (Origin recognition complex subunit Latheo) ORC3 LATHEO ORC3L Homo sapiens (Human) DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; glial cell proliferation [GO:0014009]; neural precursor cell proliferation [GO:0061351]; regulation of DNA replication [GO:0006275] "chromatin [GO:0000785]; chromosome, telomeric region [GO:0000781]; DNA replication preinitiation complex [GO:0031261]; nuclear body [GO:0016604]; nuclear origin of replication recognition complex [GO:0005664]; nuclear pre-replicative complex [GO:0005656]; nucleoplasm [GO:0005654]; origin recognition complex [GO:0000808]" DNA replication origin binding [GO:0003688] 0.71588 0.36535 DELMTILEK 0 0 0 0 0 0 0 0 0 0 10.6855 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UBD9 CLCF1_HUMAN Cardiotrophin-like cytokine factor 1 (B-cell-stimulating factor 3) (BSF-3) (Novel neurotrophin-1) (NNT-1) CLCF1 BSF3 CLC NNT1 Homo sapiens (Human) B cell differentiation [GO:0030183]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of isotype switching to IgE isotypes [GO:0048295]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; receptor signaling pathway via JAK-STAT [GO:0007259] CNTFR-CLCF1 complex [GO:0097059]; CRLF-CLCF1 complex [GO:0097058]; extracellular region [GO:0005576]; extracellular space [GO:0005615] ciliary neurotrophic factor receptor binding [GO:0005127]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; signaling receptor binding [GO:0005102] 0.75663 0.30062 ATVDLEVWR 0 0 0 0 0 0 0 0 9.59738 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UBF2 COPG2_HUMAN Coatomer subunit gamma-2 (Gamma-2-coat protein) (Gamma-2-COP) COPG2 Homo sapiens (Human) "endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; organelle transport along microtubule [GO:0072384]; protein secretion [GO:0009306]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]" COPI vesicle coat [GO:0030126]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi membrane [GO:0000139]; growth cone [GO:0030426]; transport vesicle [GO:0030133] structural molecule activity [GO:0005198] 0.88302 -0.27165 ALHQYTLEPSEKPFDMK 0 0 0 0 0 0 0 0 0 0 0 0 0 13.3993 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UBF9 MYOTI_HUMAN Myotilin (57 kDa cytoskeletal protein) (Myofibrillar titin-like Ig domains protein) (Titin immunoglobulin domain protein) MYOT TTID Homo sapiens (Human) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; muscle contraction [GO:0006936]; synapse organization [GO:0050808] actin cytoskeleton [GO:0015629]; axon [GO:0030424]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018] actin binding [GO:0003779]; alpha-actinin binding [GO:0051393]; axon guidance receptor activity [GO:0008046]; structural constituent of muscle [GO:0008307] 0.88223 -0.065027 QHAGSNPGQR 0 0 0 0 0 0 0 0 0 0 10.3104 0 0 0 0 0 0 0 0 0 0 0 0 10.0591 0 0 0 Q9UBG0 MRC2_HUMAN C-type mannose receptor 2 (C-type lectin domain family 13 member E) (Endocytic receptor 180) (Macrophage mannose receptor 2) (Urokinase-type plasminogen activator receptor-associated protein) (UPAR-associated protein) (Urokinase receptor-associated protein) (CD antigen CD280) MRC2 CLEC13E ENDO180 KIAA0709 UPARAP Homo sapiens (Human) collagen catabolic process [GO:0030574]; endocytosis [GO:0006897]; osteoblast differentiation [GO:0001649] focal adhesion [GO:0005925]; membrane [GO:0016020] carbohydrate binding [GO:0030246]; collagen binding [GO:0005518]; signaling receptor activity [GO:0038023] 0.92065 -0.91588 CLTALPYICK 0 0 0 0 0 0 0 0 0 0 8.89781 0 0 0 0 0 0 0 0 0 0 0 9.77502 0 0 0 0 Q9UBG7 RBPJL_HUMAN Recombining binding protein suppressor of hairless-like protein (Transcription factor RBP-L) RBPJL RBPL RBPSUHL Homo sapiens (Human) signal transduction [GO:0007165] chromatin [GO:0000785]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.94689 -1.3571 VSLFNRLRSQTVSTR 0 0 0 0 0 11.3138 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UBH6 S53A1_HUMAN Solute carrier family 53 member 1 (Phosphate exporter SLC53A1) (Protein SYG1 homolog) (Xenotropic and polytropic murine leukemia virus receptor X3) (X-receptor) (Xenotropic and polytropic retrovirus receptor 1) XPR1 SLC53A1 SYG1 X3 Homo sapiens (Human) cellular response to phosphate starvation [GO:0016036]; intracellular phosphate ion homeostasis [GO:0030643]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; response to virus [GO:0009615] cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886] efflux transmembrane transporter activity [GO:0015562]; inositol hexakisphosphate binding [GO:0000822]; phosphate ion transmembrane transporter activity [GO:0015114]; virus receptor activity [GO:0001618] 0.39655 0.70762 VAHVEVAPFYTCKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.92881 0 0 0 0 0 Q9UBJ2 ABCD2_HUMAN ATP-binding cassette sub-family D member 2 (EC 3.1.2.-) (EC 7.6.2.-) (Adrenoleukodystrophy-like 1) (Adrenoleukodystrophy-related protein) (hALDR) ABCD2 ALD1 ALDL1 ALDR ALDRP Homo sapiens (Human) fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid import into peroxisome [GO:0015910]; myelin maintenance [GO:0043217]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection maintenance [GO:1990535]; peroxisome organization [GO:0007031]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of unsaturated fatty acid biosynthetic process [GO:2001280]; response to bacterium [GO:0009617]; very long-chain fatty acid catabolic process [GO:0042760]; very long-chain fatty acid metabolic process [GO:0000038] cytosol [GO:0005829]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777] ABC-type transporter activity [GO:0140359]; acyl-CoA hydrolase activity [GO:0047617]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]; long-chain fatty acid transporter activity [GO:0005324]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803] 0.9697 -3.9646 IVKSIVEK 0 0 0 0 0 0 0 0 0 0 8.77814 9.08945 0 0 0 11.4896 0 0 0 0 0 0 0 0 0 0 0 Q9UBK2 PRGC1_HUMAN Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1-alpha) (PPAR-gamma coactivator 1-alpha) (PPARGC-1-alpha) (Ligand effect modulator 6) PPARGC1A LEM6 PGC1 PGC1A PPARGC1 Homo sapiens (Human) adipose tissue development [GO:0060612]; brown fat cell differentiation [GO:0050873]; cellular respiration [GO:0045333]; cellular response to oxidative stress [GO:0034599]; circadian regulation of gene expression [GO:0032922]; digestion [GO:0007586]; energy homeostasis [GO:0097009]; fatty acid oxidation [GO:0019395]; gluconeogenesis [GO:0006094]; intracellular glucose homeostasis [GO:0001678]; mitochondrion organization [GO:0007005]; mRNA processing [GO:0006397]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neuron apoptotic process [GO:0051402]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of cellular respiration [GO:1901857]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of fatty acid oxidation [GO:0046321]; positive regulation of gene expression [GO:0010628]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of histone acetylation [GO:0035066]; positive regulation of mitochondrial DNA metabolic process [GO:1901860]; positive regulation of mitochondrion organization [GO:0010822]; positive regulation of muscle tissue development [GO:1901863]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein stabilization [GO:0050821]; protein-containing complex assembly [GO:0065003]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-templated transcription [GO:0006355]; respiratory electron transport chain [GO:0022904]; response to dietary excess [GO:0002021]; response to muscle activity [GO:0014850]; response to starvation [GO:0042594]; RNA splicing [GO:0008380]; temperature homeostasis [GO:0001659]; transcription initiation at RNA polymerase II promoter [GO:0006367] chromatin [GO:0000785]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605] chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription factor binding [GO:0140297]; lncRNA binding [GO:0106222]; nuclear receptor binding [GO:0016922]; nuclear receptor coactivator activity [GO:0030374]; RNA binding [GO:0003723]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific DNA binding [GO:0043565]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription regulator activator activity [GO:0140537]; ubiquitin protein ligase binding [GO:0031625] 0.96929 -6.3961 EAQRSLRR 0 0 0 0 0 0 10.2528 10.4559 0 9.45492 9.47352 0 0 0 0 0 0 0 0 0 0 10.8628 10.64 0 0 0 0 Q9UBK8 MTRR_HUMAN Methionine synthase reductase (MSR) (EC 1.16.1.8) (Aquacobalamin reductase) (AqCbl reductase) MTRR Homo sapiens (Human) DNA methylation [GO:0006306]; folic acid metabolic process [GO:0046655]; homocysteine catabolic process [GO:0043418]; homocysteine metabolic process [GO:0050667]; methionine biosynthetic process [GO:0009086]; negative regulation of cystathionine beta-synthase activity [GO:1904042]; S-adenosylmethionine cycle [GO:0033353] cytosol [GO:0005829]; intermediate filament cytoskeleton [GO:0045111]; nucleoplasm [GO:0005654] "[methionine synthase] reductase activity [GO:0030586]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; NADPH binding [GO:0070402]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor [GO:0016723]" 0.92247 -1.0839 EHCVLLK 0 0 0 0 0 8.69418 0 0 0 0 0 0 0 0 11.6814 0 0 0 0 0 0 0 0 0 0 0 0 Q9UBK9 UXT_HUMAN Protein UXT (Androgen receptor trapped clone 27 protein) (ART-27) (Ubiquitously expressed transcript protein) UXT HSPC024 Homo sapiens (Human) apoptotic process [GO:0006915]; centrosome cycle [GO:0007098]; microtubule cytoskeleton organization [GO:0000226]; mitochondrion transport along microtubule [GO:0047497]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein stabilization [GO:0050821] centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein folding chaperone complex [GO:0101031]; RPAP3/R2TP/prefoldin-like complex [GO:1990062]; spindle pole [GO:0000922] beta-tubulin binding [GO:0048487]; chromatin binding [GO:0003682]; microtubule binding [GO:0008017]; transcription corepressor activity [GO:0003714] 0.93375 -1.2821 VLDHRDKVYEQLAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.798 0 0 0 Q9UBL3 ASH2L_HUMAN Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein) ASH2L ASH2L1 Homo sapiens (Human) DNA damage response [GO:0006974]; hemopoiesis [GO:0030097]; histone H3-K4 methylation [GO:0051568]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to estrogen [GO:0043627]; transcription initiation-coupled chromatin remodeling [GO:0045815] euchromatin [GO:0000791]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL1/2 complex [GO:0044665]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188] beta-catenin binding [GO:0008013]; metal ion binding [GO:0046872]; transcription cis-regulatory region binding [GO:0000976] 0.8823 -0.30029 FSYSWRSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.09038 0 0 0 0 0 Q9UBL6 CPNE7_HUMAN Copine-7 (Copine VII) CPNE7 Homo sapiens (Human) cellular response to calcium ion [GO:0071277]; lipid metabolic process [GO:0006629] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; plasma membrane [GO:0005886] calcium-dependent phospholipid binding [GO:0005544]; metal ion binding [GO:0046872] 0.96547 -2.7124 LSCRHLLDR 0 0 0 0 0 0 0 0 0 11.3202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UBL9 P2RX2_HUMAN P2X purinoceptor 2 (P2X2) (ATP receptor) (Purinergic receptor) P2RX2 P2X2 Homo sapiens (Human) behavioral response to pain [GO:0048266]; detection of hypoxic conditions in blood by carotid body chemoreceptor signaling [GO:0003029]; neuromuscular junction development [GO:0007528]; neuromuscular synaptic transmission [GO:0007274]; peristalsis [GO:0030432]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to hypoxia [GO:0001666]; response to ischemia [GO:0002931]; sensory perception of sound [GO:0007605]; sensory perception of taste [GO:0050909]; skeletal muscle fiber development [GO:0048741]; urinary bladder smooth muscle contraction [GO:0014832] apical plasma membrane [GO:0016324]; neuronal cell body [GO:0043025]; neuronal dense core vesicle [GO:0098992]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; receptor complex [GO:0043235] ATP binding [GO:0005524]; extracellularly ATP-gated monoatomic cation channel activity [GO:0004931]; identical protein binding [GO:0042802]; ligand-gated monoatomic ion channel activity [GO:0015276]; purinergic nucleotide receptor activity [GO:0001614] 0.95262 -1.4644 LGFIVEKAGESFTELAHK 0 0 0 0 0 0 0 0 0 9.50785 0 0 0 0 0 0 0 0 10.3868 0 0 0 0 0 0 10.9389 0 Q9UBM4 OPT_HUMAN Opticin (Oculoglycan) OPTC OPT Homo sapiens (Human) articular cartilage development [GO:0061975]; bone development [GO:0060348]; collagen fibril organization [GO:0030199] extracellular matrix [GO:0031012]; extracellular region [GO:0005576] extracellular matrix structural constituent [GO:0005201] 0.91574 -0.7686 FNRISRIR 10.1925 0 0 0 0 0 0 0 11.6424 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0749 0 0 0 0 Q9UBM7 DHCR7_HUMAN 7-dehydrocholesterol reductase (7-DHC reductase) (EC 1.3.1.21) (Delta7-sterol reductase) (Sterol Delta(7)-reductase) (Sterol reductase SR-2) DHCR7 D7SR Homo sapiens (Human) brassinosteroid biosynthetic process [GO:0016132]; cholesterol biosynthetic process [GO:0006695]; cholesterol biosynthetic process via desmosterol [GO:0033489]; cholesterol biosynthetic process via lathosterol [GO:0033490]; regulation of cholesterol biosynthetic process [GO:0045540] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; nuclear outer membrane [GO:0005640] 7-dehydrocholesterol reductase activity [GO:0047598]; NADP binding [GO:0050661]; sterol delta7 reductase activity [GO:0009918] 0.014184 1.6744 VIECSYTSADGQR 0 0 0 0 0 0 8.53193 0 9.2829 0 9.98356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UBM8 MGT4C_HUMAN "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (EC 2.4.1.145) (N-acetylglucosaminyltransferase IV homolog) (hGnT-IV-H) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc) (GlcNAc-T IVc) (GnT-IVc) (N-acetylglucosaminyltransferase IVc) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc)" MGAT4C Homo sapiens (Human) protein N-linked glycosylation [GO:0006487]; viral protein processing [GO:0019082] Golgi membrane [GO:0000139] "acetylglucosaminyltransferase activity [GO:0008375]; alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity [GO:0008454]; metal ion binding [GO:0046872]" 0.80228 0.24025 SIFEQSSYEELK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.2324 0 0 0 0 0 Q9UBN6 TR10D_HUMAN Tumor necrosis factor receptor superfamily member 10D (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD antigen CD264) TNFRSF10D DCR2 TRAILR4 TRUNDD UNQ251/PRO288 Homo sapiens (Human) apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; signal transduction [GO:0007165] cell surface [GO:0009986]; plasma membrane [GO:0005886] TRAIL binding [GO:0045569]; transmembrane signaling receptor activity [GO:0004888] 0.96978 -3.9633 GMVKVSNCTPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.5922 0 9.55042 0 Q9UBP8 KAAG1_HUMAN Kidney-associated antigen 1 (RU2 antisense gene protein) KAAG1 RU2AS Homo sapiens (Human) immune response [GO:0006955] 0.93895 -1.2962 HALHDGLR 0 0 0 0 0 0 0 0 0 0 0 8.86227 0 0 0 0 0 0 0 0 0 0 0 8.9364 0 0 0 Q9UBP9 GULP1_HUMAN PTB domain-containing engulfment adapter protein 1 (Cell death protein 6 homolog) (PTB domain adapter protein CED-6) (Protein GULP) GULP1 CED6 GULP Homo sapiens (Human) "apoptotic process [GO:0006915]; lipid transport [GO:0006869]; phagocytosis, engulfment [GO:0006911]" cytoplasm [GO:0005737] 0.69165 0.38581 ISFCADDKTDKR 9.54433 0 0 0 0 0 0 8.92582 9.37234 0 0 0 0 0 0 0 8.79828 0 0 0 0 0 0 0 0 0 0 Q9UBQ7 GRHPR_HUMAN Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81) GRHPR GLXR MSTP035 Homo sapiens (Human) carboxylic acid metabolic process [GO:0019752]; dicarboxylic acid metabolic process [GO:0043648]; glyoxylate metabolic process [GO:0046487] catalytic complex [GO:1902494]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782] carboxylic acid binding [GO:0031406]; glycerate dehydrogenase activity [GO:0008465]; glyoxylate reductase (NADP+) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; NAD binding [GO:0051287]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803] 0.90918 -0.74513 ILDAAGANLK 0 0 0 0 0 0 0 0 0 11.3339 10.7791 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UBR2 CATZ_HUMAN Cathepsin Z (EC 3.4.18.1) (Cathepsin P) (Cathepsin X) CTSZ Homo sapiens (Human) angiotensin maturation [GO:0002003]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; negative regulation of plasminogen activation [GO:0010757]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603] cell cortex [GO:0005938]; collagen-containing extracellular matrix [GO:0062023]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; plasma membrane [GO:0005886]; specific granule lumen [GO:0035580] carboxypeptidase activity [GO:0004180]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234] 0.82546 0.21275 FNQCGTCNEFK 0 10.853 0 0 0 0 0 0 0 11.4487 11.3984 9.44995 9.55907 0 0 9.80571 0 10.3781 0 0 0 0 0 0 0 0 0 Q9UBR4 LHX3_HUMAN LIM/homeobox protein Lhx3 (LIM homeobox protein 3) LHX3 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; inner ear development [GO:0048839]; lung development [GO:0030324]; medial motor column neuron differentiation [GO:0021526]; motor neuron axon guidance [GO:0008045]; negative regulation of apoptotic process [GO:0043066]; neuron differentiation [GO:0030182]; placenta development [GO:0001890]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; prolactin secreting cell differentiation [GO:0060127]; regulation of transcription by RNA polymerase II [GO:0006357]; somatotropin secreting cell differentiation [GO:0060126]; spinal cord association neuron differentiation [GO:0021527]; spinal cord motor neuron cell fate specification [GO:0021520]; thyroid-stimulating hormone-secreting cell differentiation [GO:0060129]; ventral spinal cord interneuron specification [GO:0021521] chromatin [GO:0000785]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific DNA binding [GO:0043565]; transcription coactivator binding [GO:0001223]" 0.96429 -2.4339 ALDRHWHSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.76509 0 0 0 0 9.26578 0 Q9UBS5 GABR1_HUMAN Gamma-aminobutyric acid type B receptor subunit 1 (GABA-B receptor 1) (GABA-B-R1) (GABA-BR1) (GABABR1) (Gb1) GABBR1 GPRC3A Homo sapiens (Human) "adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of dopamine secretion [GO:0033602]; negative regulation of epinephrine secretion [GO:0032811]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; negative regulation of synaptic transmission [GO:0050805]; neuron-glial cell signaling [GO:0150099]; osteoblast differentiation [GO:0001649]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of growth hormone secretion [GO:0060124]; response to ethanol [GO:0045471]; response to nicotine [GO:0035094]; synaptic transmission, GABAergic [GO:0051932]" axolemma [GO:0030673]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; G protein-coupled GABA receptor complex [GO:1902712]; G protein-coupled receptor heterodimeric complex [GO:0038039]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; Schaffer collateral - CA1 synapse [GO:0098685]; synaptic vesicle [GO:0008021] extracellular matrix protein binding [GO:1990430]; G protein-coupled GABA receptor activity [GO:0004965]; G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential [GO:0099579]; G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential [GO:0150047]; protein heterodimerization activity [GO:0046982] 0.95988 -1.9022 AINFLPVDYEIEYVCR 11.2724 11.3999 11.028 0 0 0 11.104 11.4908 11.1056 12.0993 12.1139 12.0386 0 9.74071 10.149 10.3706 10.4885 10.5494 0 0 0 0 10.7475 0 0 0 9.75852 Q9UBS8 RNF14_HUMAN E3 ubiquitin-protein ligase RNF14 (EC 2.3.2.31) (Androgen receptor-associated protein 54) (HFB30) (RING finger protein 14) RNF14 ARA54 HRIHFB2038 Homo sapiens (Human) androgen receptor signaling pathway [GO:0030521]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein K6-linked ubiquitination [GO:0085020]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; rescue of stalled ribosome [GO:0072344]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151] metal ion binding [GO:0046872]; molecular function inhibitor activity [GO:0140678]; nuclear androgen receptor binding [GO:0050681]; transcription coactivator activity [GO:0003713]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-like protein transferase activity [GO:0019787] 0.82155 0.21796 LTYHGVSPCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.66686 Q9UBS9 SUCO_HUMAN SUN domain-containing ossification factor (Membrane protein CH1) (Protein osteopotentia homolog) (SUN-like protein 1) SUCO C1orf9 CH1 OPT SLP1 Homo sapiens (Human) ossification [GO:0001503]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of bone remodeling [GO:0046850] cytoplasm [GO:0005737]; membrane [GO:0016020]; rough endoplasmic reticulum [GO:0005791]; rough endoplasmic reticulum membrane [GO:0030867] 0.8984 -0.65391 DFLVSISDR 0 0 0 9.06007 0 0 9.94848 0 0 0 10.8349 0 0 0 0 11.4888 10.3156 9.38319 9.86813 0 0 9.93127 9.9621 10.1001 0 11.5555 10.3309 Q9UBT2 SAE2_HUMAN SUMO-activating enzyme subunit 2 (EC 2.3.2.-) (Anthracycline-associated resistance ARX) (Ubiquitin-like 1-activating enzyme E1B) (Ubiquitin-like modifier-activating enzyme 2) UBA2 SAE2 UBLE1B HRIHFB2115 Homo sapiens (Human) positive regulation of protein sumoylation [GO:0033235]; protein sumoylation [GO:0016925] cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; SUMO activating enzyme complex [GO:0031510] ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; small protein activating enzyme binding [GO:0044388]; SUMO activating enzyme activity [GO:0019948]; SUMO binding [GO:0032183]; transferase activity [GO:0016740]; ubiquitin-like protein conjugating enzyme binding [GO:0044390] 0.95429 -1.5354 IDQCRTIFLNK 0 0 9.41692 0 0 0 0 0 0 0 0 0 0 9.63307 0 0 0 0 0 0 0 0 0 0 9.05249 0 0 Q9UBT3 DKK4_HUMAN Dickkopf-related protein 4 (Dickkopf-4) (Dkk-4) (hDkk-4) [Cleaved into: Dickkopf-related protein 4 short form] DKK4 Homo sapiens (Human) negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of hair follicle placode formation [GO:0061170]; negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055] extracellular space [GO:0005615] co-receptor binding [GO:0039706]; receptor antagonist activity [GO:0048019] 0.7283 0.34509 GSQCLSDTDCNTR 0 0 0 0 0 0 9.85468 0 10.9894 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UBT6 POLK_HUMAN DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP) POLK DINB1 Homo sapiens (Human) "cellular response to UV [GO:0034644]; DNA damage response [GO:0006974]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276]; nucleotide-excision repair, DNA gap filling [GO:0006297]" nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872] 0.96 -1.9079 LRLMGVR 0 0 8.62604 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UBT7 CTNL1_HUMAN Alpha-catulin (Alpha-catenin-related protein) (ACRP) (Catenin alpha-like protein 1) CTNNAL1 Homo sapiens (Human) cell adhesion [GO:0007155]; Rho protein signal transduction [GO:0007266] cytoskeleton [GO:0005856]; cytosol [GO:0005829]; plasma membrane [GO:0005886] actin filament binding [GO:0051015]; cadherin binding [GO:0045296] 0.92304 -1.1587 EGVFDRMKVALDK 0 0 0 0 10.2425 10.1348 9.96049 10.1767 0 0 0 0 0 11.8318 0 10.2268 10.2797 0 0 0 9.93777 0 0 0 0 0 0 Q9UBU7 DBF4A_HUMAN Protein DBF4 homolog A (Activator of S phase kinase) (Chiffon homolog A) (DBF4-type zinc finger-containing protein 1) DBF4 ASK DBF4A ZDBF1 Homo sapiens (Human) DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; positive regulation of nuclear cell cycle DNA replication [GO:0010571]; regulation of cell cycle phase transition [GO:1901987] Dbf4-dependent protein kinase complex [GO:0031431]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654] enzyme activator activity [GO:0008047]; nucleic acid binding [GO:0003676]; protein serine/threonine kinase activator activity [GO:0043539]; zinc ion binding [GO:0008270] 0.93308 -1.2657 KKGYCECCLQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.91085 0 0 0 0 0 0 0 0 0 0 0 Q9UBU8 MO4L1_HUMAN Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Protein MSL3-1) (Transcription factor-like protein MRG15) MORF4L1 MRG15 FWP006 HSPC008 HSPC061 PP368 Homo sapiens (Human) chromatin organization [GO:0006325]; double-strand break repair via homologous recombination [GO:0000724]; fibroblast proliferation [GO:0048144]; histone acetylation [GO:0016573]; histone deacetylation [GO:0016575]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of double-strand break repair [GO:2000779] NuA4 histone acetyltransferase complex [GO:0035267]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; Sin3 complex [GO:0016580] chromatin binding [GO:0003682] 0.32208 0.78675 GAAPGKK 10.8154 0 10.7383 0 0 0 11.2483 11.3766 11.4276 9.32321 9.41318 9.57628 0 0 0 0 11.3196 0 9.25307 0 0 0 10.1427 0 10.6423 0 0 Q9UBU9 NXF1_HUMAN Nuclear RNA export factor 1 (Tip-associated protein) (Tip-associating protein) (mRNA export factor TAP) NXF1 TAP Homo sapiens (Human) mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; protein transport [GO:0015031] cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear RNA export factor complex [GO:0042272]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] mRNA binding [GO:0003729]; RNA binding [GO:0003723] 0.97017 -5.2079 ILDRENR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0373 0 0 0 0 0 0 0 0 0 0 0 Q9UBV2 SE1L1_HUMAN Protein sel-1 homolog 1 (Suppressor of lin-12-like protein 1) (Sel-1L) SEL1L TSA305 UNQ128/PRO1063 Homo sapiens (Human) "ERAD pathway [GO:0036503]; Notch signaling pathway [GO:0007219]; protein secretion [GO:0009306]; protein stabilization [GO:0050821]; retrograde protein transport, ER to cytosol [GO:0030970]; triglyceride metabolic process [GO:0006641]; ubiquitin-dependent ERAD pathway [GO:0030433]" Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Hrd1p ubiquitin ligase complex [GO:0000836]; Hrd1p ubiquitin ligase ERAD-L complex [GO:0000839] 0.88401 -0.055633 LASEQQHSAQAMFNLGYMHEK 0 0 0 0 0 0 0 0 0 0 0 10.1779 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UBV7 B4GT7_HUMAN "Beta-1,4-galactosyltransferase 7 (Beta-1,4-GalTase 7) (Beta4Gal-T7) (b4Gal-T7) (EC 2.4.1.-) (Proteoglycan UDP-galactose:beta-xylose beta1,4-galactosyltransferase I) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 7) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 7) (UDP-galactose:beta-xylose beta-1,4-galactosyltransferase) (XGPT) (XGalT-1) (Xylosylprotein 4-beta-galactosyltransferase) (EC 2.4.1.133) (Xylosylprotein beta-1,4-galactosyltransferase)" B4GALT7 XGALT1 UNQ748/PRO1478 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan metabolic process [GO:0030203]; negative regulation of fibroblast proliferation [GO:0048147]; protein modification process [GO:0036211]; protein N-linked glycosylation [GO:0006487]; proteoglycan biosynthetic process [GO:0030166]; proteoglycan metabolic process [GO:0006029]; supramolecular fiber organization [GO:0097435] Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; membrane [GO:0016020] "beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; galactosyltransferase activity [GO:0008378]; manganese ion binding [GO:0030145]; xylosylprotein 4-beta-galactosyltransferase activity [GO:0046525]" 0.95266 -1.4672 TFRHLHDPAWR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.6751 0 Q9UBW7 ZMYM2_HUMAN Zinc finger MYM-type protein 2 (Fused in myeloproliferative disorders protein) (Rearranged in atypical myeloproliferative disorder protein) (Zinc finger protein 198) ZMYM2 FIM RAMP ZNF198 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892] cytosol [GO:0005829]; nucleus [GO:0005634]; PML body [GO:0016605] ubiquitin conjugating enzyme binding [GO:0031624]; zinc ion binding [GO:0008270] 0.96241 -2.0798 CVTCNYCSQLCK 0 0 0 0 0 0 0 0 0 0 10.029 9.03722 0 0 11.0046 0 0 0 0 9.84119 0 0 8.91373 0 0 0 0 Q9UBW8 CSN7A_HUMAN COP9 signalosome complex subunit 7a (SGN7a) (Signalosome subunit 7a) (Dermal papilla-derived protein 10) (JAB1-containing signalosome subunit 7a) COPS7A CSN7A DERP10 Homo sapiens (Human) COP9 signalosome assembly [GO:0010387]; protein deneddylation [GO:0000338]; protein neddylation [GO:0045116]; regulation of protein neddylation [GO:2000434] COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.91057 -0.74821 EPAPGTNQRQPSKK 10.9638 10.9064 0 0 0 0 0 12.5971 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UBX1 CATF_HUMAN Cathepsin F (CATSF) (EC 3.4.22.41) CTSF Homo sapiens (Human) antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603] collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; plasma membrane [GO:0005886] cysteine-type endopeptidase activity [GO:0004197] 0.88337 -0.060749 SAFTQGSAMISSLSQNHPDNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0783 0 0 0 0 0 0 Q9UBX7 KLK11_HUMAN Kallikrein-11 (hK11) (EC 3.4.21.-) (Hippostasin) (Serine protease 20) (Trypsin-like protease) [Cleaved into: Kallikrein-11 inactive chain 1; Kallikrein-11 inactive chain 2] KLK11 PRSS20 TLSP UNQ649/PRO1279 Homo sapiens (Human) proteolysis [GO:0006508] extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794] serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236] 0.89717 -0.52486 ILQLILLALATGLVGGETRIIK 0 0 0 0 0 9.34127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UBX8 B4GT6_HUMAN "Beta-1,4-galactosyltransferase 6 (Beta-1,4-GalTase 6) (Beta4Gal-T6) (b4Gal-T6) (EC 2.4.1.-) (Glucosylceramide beta-1,4-galactosyltransferase) (EC 2.4.1.274) (Lactosylceramide synthase) (LacCer synthase) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 6) (UDP-Gal:glucosylceramide beta-1,4-galactosyltransferase) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 6)" B4GALT6 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; central nervous system myelination [GO:0022010]; central nervous system neuron axonogenesis [GO:0021955]; ganglioside biosynthetic process via lactosylceramide [GO:0010706]; glycosphingolipid biosynthetic process [GO:0006688]; lactosylceramide biosynthetic process [GO:0001572]; neuron maturation [GO:0042551]; protein glycosylation [GO:0006486] Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139] "galactosyltransferase activity [GO:0008378]; metal ion binding [GO:0046872]; UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity [GO:0008489]" 0.93999 -1.2978 GIMLRENVK 0 0 0 0 0 0 0 0 0 0 11.6812 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UBY0 SL9A2_HUMAN Sodium/hydrogen exchanger 2 (Na(+)/H(+) exchanger 2) (NHE-2) (Solute carrier family 9 member 2) SLC9A2 NHE2 Homo sapiens (Human) epithelial cell differentiation [GO:0030855]; monoatomic ion transport [GO:0006811]; potassium ion transmembrane transport [GO:0071805]; protein localization [GO:0008104]; regulation of intracellular pH [GO:0051453]; sodium ion import across plasma membrane [GO:0098719] apical plasma membrane [GO:0016324]; membrane [GO:0016020]; plasma membrane [GO:0005886] potassium:proton antiporter activity [GO:0015386]; sodium:proton antiporter activity [GO:0015385] 0.54529 0.57035 ASTSTSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.79084 0 0 0 0 8.82257 0 0 0 Q9UBZ4 APEX2_HUMAN DNA-(apurinic or apyrimidinic site) endonuclease 2 (EC 3.1.11.2) (AP endonuclease XTH2) (APEX nuclease 2) (APEX nuclease-like 2) (Apurinic-apyrimidinic endonuclease 2) (AP endonuclease 2) APEX2 APE2 APEXL2 XTH2 Homo sapiens (Human) base-excision repair [GO:0006284]; cell cycle [GO:0007049]; DNA recombination [GO:0006310] fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; double-stranded DNA 3'-5' DNA exonuclease activity [GO:0008311]; endonuclease activity [GO:0004519]; phosphoric diester hydrolase activity [GO:0008081]; zinc ion binding [GO:0008270] 0.9621 -2.4535 GQAKTSEAK 0 0 0 0 0 0 0 0 0 10.1787 0 0 0 0 0 0 0 0 0 9.65644 0 0 0 0 0 0 0 Q9UBZ9 REV1_HUMAN DNA repair protein REV1 (EC 2.7.7.-) (Alpha integrin-binding protein 80) (AIBP80) (Rev1-like terminal deoxycytidyl transferase) REV1 REV1L Homo sapiens (Human) DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; response to UV [GO:0009411] nucleoplasm [GO:0005654] damaged DNA binding [GO:0003684]; deoxycytidyl transferase activity [GO:0017125]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872] 0.96409 -2.4048 AAVDLEISSASR 0 0 11.855 0 0 0 0 11.7757 0 0 0 8.98445 10.0554 0 0 9.38107 0 0 0 0 0 0 0 0 0 8.5467 0 Q9UC06 ZNF70_HUMAN Zinc finger protein 70 (Zinc finger protein N27C7-1) ZNF70 Homo sapiens (Human) cytoplasm [GO:0005737]; megasporocyte nucleus [GO:0043076] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.82215 0.21772 GLEQMAVIYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8719 0 0 0 0 0 0 0 0 0 0 0 Q9UC07 ZNF69_HUMAN Zinc finger protein 69 (hZNF3) ZNF69 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]" 0.89847 -0.62136 EVMLETFRNLTSVGK 0 0 0 9.39363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UDT6 CLIP2_HUMAN CAP-Gly domain-containing linker protein 2 (Cytoplasmic linker protein 115) (CLIP-115) (Cytoplasmic linker protein 2) (Williams-Beuren syndrome chromosomal region 3 protein) (Williams-Beuren syndrome chromosomal region 4 protein) CLIP2 CYLN2 KIAA0291 WBSCR3 WBSCR4 WSCR4 Homo sapiens (Human) cytoplasmic microtubule organization [GO:0031122] cell cortex [GO:0005938]; microtubule associated complex [GO:0005875]; microtubule plus-end [GO:0035371]; nucleus [GO:0005634] microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010] 0.96748 -2.9682 AEAQGKQEVESLR 0 0 0 0 8.66633 0 0 0 0 0 0 0 9.72768 0 0 0 0 0 10.6069 0 0 0 0 0 0 0 0 Q9UDV6 ZN212_HUMAN Zinc finger protein 212 (Zinc finger protein C2H2-150) ZNF212 ZNFC150 Homo sapiens (Human) "dendrite development [GO:0016358]; general adaptation syndrome, behavioral process [GO:0051867]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; response to alcohol [GO:0097305]; walking behavior [GO:0090659]" nucleoplasm [GO:0005654] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; zinc ion binding [GO:0008270]" 0.9563 -1.5433 LADCEKMAVEFGNQLEGK 9.89207 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UDV7 ZN282_HUMAN Zinc finger protein 282 (HTLV-I U5RE-binding protein 1) (HUB-1) ZNF282 HUB1 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] sequence-specific double-stranded DNA binding [GO:1990837]; zinc ion binding [GO:0008270] 0.94707 -1.356 GERPYKCSECEKTYSR 0 0 0 0 0 0 0 0 0 9.91792 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UDX3 S14L4_HUMAN SEC14-like protein 4 (Tocopherol-associated protein 3) SEC14L4 TAP3 Homo sapiens (Human) cytoplasm [GO:0005737] lipid binding [GO:0008289] 0.55983 0.5252 IVILGDNWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6277 0 0 10.6869 0 0 0 0 0 0 0 0 Q9UDX5 MTFP1_HUMAN Mitochondrial fission process protein 1 (Mitochondrial 18 kDa protein) (MTP18) MTFP1 MTP18 HSPC242 My022 Homo sapiens (Human) apoptotic process [GO:0006915]; mitochondrial fission [GO:0000266]; response to muscle activity [GO:0014850] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] 0.95504 -1.5645 AGEVPSPEAGRSAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.27433 0 0 0 0 0 0 0 Q9UDY2 ZO2_HUMAN Tight junction protein ZO-2 (Tight junction protein 2) (Zona occludens protein 2) (Zonula occludens protein 2) TJP2 X104 ZO2 Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cell-cell junction organization [GO:0045216]; establishment of endothelial intestinal barrier [GO:0090557]; homotypic cell-cell adhesion [GO:0034109]; intestinal absorption [GO:0050892]; maintenance of blood-brain barrier [GO:0035633]; positive regulation of blood-brain barrier permeability [GO:1905605]; protein localization to cell-cell junction [GO:0150105]; regulation of membrane permeability [GO:0090559] adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cell-cell contact zone [GO:0044291]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; guanylate kinase activity [GO:0004385]; protein domain specific binding [GO:0019904]; protein tyrosine kinase binding [GO:1990782]; protein-macromolecule adaptor activity [GO:0030674] 0.96808 -2.758 GARHDAR 0 0 0 0 0 0 0 0 0 0 10.8554 10.3103 0 0 8.99396 10.4892 0 0 9.38271 0 0 9.06018 8.78044 0 10.3383 0 0 Q9UDY4 DNJB4_HUMAN DnaJ homolog subfamily B member 4 (Heat shock 40 kDa protein 1 homolog) (HSP40 homolog) (Heat shock protein 40 homolog) (Human liver DnaJ-like protein) DNAJB4 DNAJW HLJ1 Homo sapiens (Human) chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of transcription by RNA polymerase II [GO:0000122]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] ATPase activator activity [GO:0001671]; protein-folding chaperone binding [GO:0051087]; unfolded protein binding [GO:0051082] 0.96194 -2.6149 EVLRKHLPAS 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7368 10.7687 Q9UEE5 ST17A_HUMAN Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 1) STK17A DRAK1 Homo sapiens (Human) apoptotic process [GO:0006915]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fibroblast apoptotic process [GO:2000271]; protein phosphorylation [GO:0006468]; regulation of reactive oxygen species metabolic process [GO:2000377] nuclear speck [GO:0016607]; nucleus [GO:0005634]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.93218 -1.2748 QSEKEKMEQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4042 0 0 0 Q9UEF7 KLOT_HUMAN Klotho (EC 3.2.1.31) [Cleaved into: Klotho peptide] KL Homo sapiens (Human) acute inflammatory response [GO:0002526]; aging [GO:0007568]; calcium ion homeostasis [GO:0055074]; carbohydrate metabolic process [GO:0005975]; energy reserve metabolic process [GO:0006112]; fibroblast growth factor receptor signaling pathway [GO:0008543]; negative regulation of systemic arterial blood pressure [GO:0003085]; norepinephrine biosynthetic process [GO:0042421]; positive regulation of bone mineralization [GO:0030501]; positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway [GO:0090080]; response to activity [GO:0014823]; response to angiotensin [GO:1990776]; response to vitamin D [GO:0033280] apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886] beta-glucosidase activity [GO:0008422]; beta-glucuronidase activity [GO:0004566]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor receptor binding [GO:0005104]; hormone activity [GO:0005179]; vitamin D binding [GO:0005499] 0.69755 0.37436 FIMETLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4941 0 0 0 0 0 0 0 0 0 0 Q9UEG4 ZN629_HUMAN Zinc finger protein 629 (Zinc finger protein 65) ZNF629 KIAA0326 ZNF65 Homo sapiens (Human) nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.95301 -1.5006 HQKIHAGEKPYR 8.95324 0 0 0 0 0 0 9.81084 0 0 0 8.69943 0 0 0 0 0 0 0 0 0 0 0 11.5133 0 0 0 Q9UEU0 VTI1B_HUMAN Vesicle transport through interaction with t-SNAREs homolog 1B (Vesicle transport v-SNARE protein Vti1-like 1) (Vti1-rp1) VTI1B VTI1 VTI1L VTI1L1 VTI2 Homo sapiens (Human) "Golgi to vacuole transport [GO:0006896]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; macroautophagy [GO:0016236]; membrane fusion [GO:0061025]; regulation of protein localization to plasma membrane [GO:1903076]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle docking involved in exocytosis [GO:0006904]; vesicle fusion with Golgi apparatus [GO:0048280]; vesicle-mediated transport [GO:0016192]" cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471]; platelet alpha granule lumen [GO:0031093]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; SNARE complex [GO:0031201]; synaptic vesicle [GO:0008021]; vesicle [GO:0031982] chloride channel inhibitor activity [GO:0019869]; SNAP receptor activity [GO:0005484]; SNARE binding [GO:0000149] 0.94353 -1.3342 GLHEDLQGVPERLLGTAGTEEKK 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0901 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UEY8 ADDG_HUMAN Gamma-adducin (Adducin-like protein 70) ADD3 ADDL Homo sapiens (Human) barbed-end actin filament capping [GO:0051016] brush border [GO:0005903]; cell cortex [GO:0005938]; cell-cell junction [GO:0005911]; condensed nuclear chromosome [GO:0000794]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] actin filament binding [GO:0051015]; calmodulin binding [GO:0005516]; structural constituent of cytoskeleton [GO:0005200] 0.95086 -1.4166 INENDPEYIRER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.61671 8.88829 0 0 0 0 10.484 0 0 10.3036 0 0 Q9UF12 HYPDH_HUMAN Hydroxyproline dehydrogenase (HYPDH) (EC 1.5.5.3) (Kidney and liver proline oxidase 1) (HsPOX1) (Probable proline dehydrogenase 2) (EC 1.5.5.2) (Probable proline oxidase 2) PRODH2 HSPOX1 HYPDH Homo sapiens (Human) proline catabolic process [GO:0006562]; proline catabolic process to glutamate [GO:0010133] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] "FAD binding [GO:0071949]; oxidoreductase activity, acting on the CH-NH group of donors [GO:0016645]; proline dehydrogenase activity [GO:0004657]" 0.95428 -1.5091 VAQYARAQHVR 9.26964 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.13681 0 0 0 Q9UF33 EPHA6_HUMAN Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2) (EPH-like kinase 12) (EK12) EPHA6 EHK2 HEK12 Homo sapiens (Human) axon guidance [GO:0007411]; ephrin receptor signaling pathway [GO:0048013]; protein phosphorylation [GO:0006468] dendrite [GO:0030425]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; transmembrane-ephrin receptor activity [GO:0005005] 0.92836 -1.227 AKMKSEEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.71516 8.95542 0 0 0 0 0 0 Q9UF56 FXL17_HUMAN F-box/LRR-repeat protein 17 (F-box and leucine-rich repeat protein 17) (F-box only protein 13) FBXL17 FBL17 FBX13 FBXO13 Homo sapiens (Human) entrainment of circadian clock by photoperiod [GO:0043153]; nervous system development [GO:0007399]; neural crest cell differentiation [GO:0014033]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein ubiquitination [GO:0016567]; regulation of smoothened signaling pathway [GO:0008589]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005] 0.89863 -0.64453 CCSWCRRR 0 0 0 8.34855 0 8.4458 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UFC0 LRWD1_HUMAN Leucine-rich repeat and WD repeat-containing protein 1 (Centromere protein 33) (CENP-33) (Origin recognition complex-associated protein) (ORC-associated protein) (ORCA) LRWD1 CENP-33 ORCA Homo sapiens (Human) chromatin organization [GO:0006325]; DNA replication initiation [GO:0006270]; establishment of protein localization to chromatin [GO:0071169] "chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; kinetochore [GO:0000776]; microtubule organizing center [GO:0005815]; nuclear origin of replication recognition complex [GO:0005664]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]" chromatin binding [GO:0003682]; methyl-CpG binding [GO:0008327]; methylated histone binding [GO:0035064] 0.87126 0.052642 DVRYGPESLSEFTQWR 0 0 0 0 0 9.18051 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UFD9 RIM3A_HUMAN RIMS-binding protein 3A (RIM-BP3.A) (RIMS-binding protein 3.1) (RIM-BP3.1) RIMBP3 KIAA1666 RIMBP3A Homo sapiens (Human) fertilization [GO:0009566]; spermatid development [GO:0007286] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; nucleus [GO:0005634] benzodiazepine receptor binding [GO:0030156] 0.96898 -6.7573 AGCPYQADEKVK 9.65458 10.7635 0 0 0 0 9.11333 0 0 9.42454 0 0 0 9.03917 0 9.17971 9.18021 9.36934 0 0 0 10.9347 0 0 9.68678 9.73471 11.0065 Q9UFE4 CCD39_HUMAN Coiled-coil domain-containing protein 39 CCDC39 Homo sapiens (Human) axonemal dynein complex assembly [GO:0070286]; brain development [GO:0007420]; cerebrospinal fluid circulation [GO:0090660]; cilium movement [GO:0003341]; cilium-dependent cell motility [GO:0060285]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment of left/right asymmetry [GO:0061966]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart looping [GO:0001947]; inner dynein arm assembly [GO:0036159]; lung development [GO:0030324]; motile cilium assembly [GO:0044458]; protein localization to cilium [GO:0061512]; regulation of cilium beat frequency [GO:0003356] axoneme [GO:0005930]; cilium [GO:0005929]; cytosol [GO:0005829]; extracellular region [GO:0005576] 0.82941 0.20775 AEEVLSLEKR 0 0 0 0 9.81187 9.77035 0 0 14.4463 11.207 10.9911 0 8.982 10.2319 10.6812 10.0721 9.67562 9.47887 10.3623 9.5598 10.2582 0 9.95797 0 0 9.24779 0 Q9UFF9 CNOT8_HUMAN CCR4-NOT transcription complex subunit 8 (EC 3.1.13.4) (CAF1-like protein) (CALIFp) (CAF2) (CCR4-associated factor 8) (Caf1b) CNOT8 CALIF POP2 Homo sapiens (Human) exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; miRNA-mediated gene silencing [GO:0035195]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of mRNA catabolic process [GO:0061014] CCR4-NOT complex [GO:0030014]; CCR4-NOT core complex [GO:0030015]; cytosol [GO:0005829]; nucleus [GO:0005634]; P-body [GO:0000932] 3'-5'-RNA exonuclease activity [GO:0000175]; metal ion binding [GO:0046872]; poly(A)-specific ribonuclease activity [GO:0004535]; RNA binding [GO:0003723] 0.90479 -0.70739 MKELFFEDSIDDAK 0 0 0 0 0 0 0 0 0 0 11.8641 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UFH2 DYH17_HUMAN Dynein axonemal heavy chain 17 (Axonemal beta dynein heavy chain 17) (Axonemal dynein heavy chain-like protein 1) (Ciliary dynein heavy chain 17) (Ciliary dynein heavy chain-like protein 1) (Dynein axonemal light chain 2) DNAH17 DNAHL1 DNEL2 Homo sapiens (Human) cilium movement [GO:0003341]; cilium-dependent cell motility [GO:0060285]; outer dynein arm assembly [GO:0036158] axonemal dynein complex [GO:0005858]; axoneme [GO:0005930]; dynein complex [GO:0030286]; microtubule [GO:0005874]; motile cilium [GO:0031514]; outer dynein arm [GO:0036157]; sperm flagellum [GO:0036126] ATP binding [GO:0005524]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; microtubule motor activity [GO:0003777]; minus-end-directed microtubule motor activity [GO:0008569] 0.9683 -3.8389 ACHREVR 9.56516 0 0 0 0 0 0 0 11.2409 10.7672 0 10.2384 0 11.3551 0 0 12.0972 10.5069 0 0 9.10066 0 10.0966 9.54473 9.31687 8.94805 0 Q9UFP1 GAK1A_HUMAN Golgi-associated kinase 1A (Protein FAM198A) GASK1A C3orf41 FAM198A Homo sapiens (Human) caveola [GO:0005901]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231] 0.95121 -1.4327 LLEGIDGFPESAVK 8.70957 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.87394 0 0 0 0 0 0 0 0 Q9UFV3 YO007_HUMAN Putative uncharacterized protein DKFZp434L187 Homo sapiens (Human) 0.8991 -0.61528 TTPNVWYK 0 0 0 0 9.0334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.11512 0 0 9.5457 9.42291 0 0 0 Q9UFW8 CGBP1_HUMAN CGG triplet repeat-binding protein 1 (CGG-binding protein 1) (20 kDa CGG-binding protein) (p20-CGGBP DNA-binding protein) CGGBP1 CGGBP Homo sapiens (Human) epigenetic regulation of gene expression [GO:0040029]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of gene expression [GO:0010468] nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA-binding transcription factor binding [GO:0140297]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802] 0.89701 -0.53845 AEFEEQNVR 0 0 0 0 0 8.91776 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UG01 IF172_HUMAN Intraflagellar transport protein 172 homolog IFT172 KIAA1179 Homo sapiens (Human) bone development [GO:0060348]; brain development [GO:0007420]; cilium assembly [GO:0060271]; cytoplasmic microtubule organization [GO:0031122]; dorsal/ventral pattern formation [GO:0009953]; embryonic camera-type eye morphogenesis [GO:0048596]; epidermis development [GO:0008544]; heart looping [GO:0001947]; hindgut development [GO:0061525]; intraciliary anterograde transport [GO:0035720]; intraciliary transport [GO:0042073]; keratinocyte proliferation [GO:0043616]; left/right axis specification [GO:0070986]; limb development [GO:0060173]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of smoothened signaling pathway [GO:0045879]; neural tube closure [GO:0001843]; non-motile cilium assembly [GO:1905515]; Notch signaling pathway [GO:0007219]; positive regulation of smoothened signaling pathway [GO:0045880]; protein processing [GO:0016485]; roof of mouth development [GO:0060021]; smoothened signaling pathway [GO:0007224]; spinal cord motor neuron differentiation [GO:0021522] axoneme [GO:0005930]; ciliary basal body [GO:0036064]; ciliary tip [GO:0097542]; cilium [GO:0005929]; extracellular vesicle [GO:1903561]; intraciliary transport particle B [GO:0030992]; sperm cytoplasmic droplet [GO:0097598]; sperm midpiece [GO:0097225]; sperm principal piece [GO:0097228] 0.88384 -0.055786 ATAFLETLEMTPETEAMWK 0 0 0 0 0 0 10.651 9.0124 9.19444 0 0 11.314 0 0 10.6726 0 0 0 0 0 0 0 0 9.82152 0 0 0 Q9UG22 GIMA2_HUMAN GTPase IMAP family member 2 (Immunity-associated protein 2) (hIMAP2) GIMAP2 IMAP2 Homo sapiens (Human) endoplasmic reticulum [GO:0005783]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654] GTP binding [GO:0005525]; identical protein binding [GO:0042802] 0.94074 -1.313 LERKTPR 0 0 0 0 0 0 10.5351 0 0 0 0 0 0 0 0 0 0 0 11.1673 0 0 0 0 0 0 0 0 Q9UG63 ABCF2_HUMAN ATP-binding cassette sub-family F member 2 (Iron-inhibited ABC transporter 2) ABCF2 HUSSY-18 Homo sapiens (Human) membrane [GO:0016020] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887] 0.72644 0.35153 EMPPSDKTPLHCVMEVDTER 0 9.90111 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.76694 0 Q9UGC7 RF1ML_HUMAN "Peptide chain release factor 1-like, mitochondrial (Mitochondrial translational release factor 1-like) (mtRF1a)" MTRF1L MTRF1A Homo sapiens (Human) mitochondrial translational termination [GO:0070126] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] translation release factor activity [GO:0003747] 0.91577 -0.77308 TYNFPQNRVTDHR 9.65051 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UGI6 KCNN3_HUMAN Small conductance calcium-activated potassium channel protein 3 (SK3) (SKCa 3) (SKCa3) (KCa2.3) KCNN3 K3 Homo sapiens (Human) potassium ion transmembrane transport [GO:0071805] cytoplasm [GO:0005737]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886] calmodulin binding [GO:0005516]; inward rectifier potassium channel activity [GO:0005242]; small conductance calcium-activated potassium channel activity [GO:0016286] 0.96256 -2.5484 LAFSYTPSR 0 0 0 0 0 0 10.9189 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UGJ0 AAKG2_HUMAN 5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma2) (AMPK subunit gamma-2) (H91620p) PRKAG2 Homo sapiens (Human) ATP biosynthetic process [GO:0006754]; cellular response to nutrient levels [GO:0031669]; fatty acid biosynthetic process [GO:0006633]; glycogen metabolic process [GO:0005977]; intracellular signal transduction [GO:0035556]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase activity [GO:0045860]; protein phosphorylation [GO:0006468]; regulation of fatty acid metabolic process [GO:0019217]; regulation of fatty acid oxidation [GO:0046320]; regulation of glucose import [GO:0046324]; regulation of glycolytic process [GO:0006110]; sterol biosynthetic process [GO:0016126] cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588] ADP binding [GO:0043531]; AMP binding [GO:0016208]; AMP-activated protein kinase activity [GO:0004679]; ATP binding [GO:0005524]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; cAMP-dependent protein kinase regulator activity [GO:0008603]; phosphorylase kinase regulator activity [GO:0008607]; protein kinase activator activity [GO:0030295]; protein kinase binding [GO:0019901] 0.84775 0.16871 SPMVQIYELEEHK 0 0 0 0 0 9.94067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UGJ1 GCP4_HUMAN Gamma-tubulin complex component 4 (GCP-4) (hGCP4) (Gamma-ring complex protein 76 kDa) (h76p) (hGrip76) TUBGCP4 76P GCP4 Homo sapiens (Human) cytoplasmic microtubule organization [GO:0031122]; meiotic cell cycle [GO:0051321]; microtubule nucleation [GO:0007020]; mitotic cell cycle [GO:0000278]; protein-containing complex assembly [GO:0065003]; spindle assembly [GO:0051225] centrosome [GO:0005813]; cytosol [GO:0005829]; equatorial microtubule organizing center [GO:0000923]; gamma-tubulin complex [GO:0000930]; gamma-tubulin ring complex [GO:0000931]; membrane [GO:0016020]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; recycling endosome [GO:0055037]; spindle pole [GO:0000922] gamma-tubulin binding [GO:0043015]; structural constituent of cytoskeleton [GO:0005200] 0.96391 -2.405 ADATQAR 0 0 0 0 0 0 0 7.99016 0 0 0 0 0 0 0 0 0 0 0 0 0 8.87301 0 0 0 0 0 Q9UGK8 SRGEF_HUMAN Secretion-regulating guanine nucleotide exchange factor (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF) (Guanine nucleotide exchange factor-related protein) SERGEF DELGEF GNEFR Homo sapiens (Human) negative regulation of protein secretion [GO:0050709]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] guanyl-nucleotide exchange factor activity [GO:0005085] 0.96358 -2.2283 EPSRVTGLENSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.84444 0 0 0 Q9UGL1 KDM5B_HUMAN Lysine-specific demethylase 5B (EC 1.14.11.67) (Cancer/testis antigen 31) (CT31) (Histone demethylase JARID1B) (Jumonji/ARID domain-containing protein 1B) (PLU-1) (Retinoblastoma-binding protein 2 homolog 1) (RBP2-H1) ([histone H3]-trimethyl-L-lysine(4) demethylase 5B) KDM5B JARID1B PLU1 RBBP2H1 Homo sapiens (Human) branching involved in mammary gland duct morphogenesis [GO:0060444]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to leukemia inhibitory factor [GO:1990830]; chromatin remodeling [GO:0006338]; lens fiber cell differentiation [GO:0070306]; mammary duct terminal end bud growth [GO:0060763]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of mammary gland epithelial cell proliferation [GO:0033601]; post-embryonic development [GO:0009791]; regulation of estradiol secretion [GO:2000864]; response to fungicide [GO:0060992]; rhythmic process [GO:0048511]; single fertilization [GO:0007338]; uterus morphogenesis [GO:0061038] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; histone binding [GO:0042393]; histone demethylase activity [GO:0032452]; histone H3K4 demethylase activity [GO:0032453]; histone H3K4me/H3K4me2/H3K4me3 demethylase activity [GO:0034647]; nucleic acid binding [GO:0003676]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription corepressor activity [GO:0003714]; zinc ion binding [GO:0008270] 0.9528 -1.4916 AMARLQELLTVSEHWDDKAK 9.87915 9.35416 0 0 0 9.21006 0 0 8.45327 0 8.81227 0 0 0 10.1226 0 0 8.60596 0 0 0 0 0 10.5602 0 0 0 Q9UGM3 DMBT1_HUMAN Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) DMBT1 GP340 Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of membrane [GO:0019898]; phagocytic vesicle membrane [GO:0030670]; zymogen granule membrane [GO:0042589] calcium-dependent protein binding [GO:0048306]; DNA binding [GO:0003677]; heparan sulfate binding [GO:1904399]; lipopolysaccharide binding [GO:0001530]; lipoteichoic acid binding [GO:0070891]; pattern recognition receptor activity [GO:0038187]; scavenger receptor activity [GO:0005044]; zymogen binding [GO:0035375] 0.8845 -0.29854 CQGRVEILYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3391 0 9.10554 Q9UGM6 SYWM_HUMAN "Tryptophan--tRNA ligase, mitochondrial (EC 6.1.1.2) ((Mt)TrpRS) (Tryptophanyl-tRNA synthetase) (TrpRS)" WARS2 Homo sapiens (Human) mitochondrial tryptophanyl-tRNA aminoacylation [GO:0070183]; positive regulation of angiogenesis [GO:0045766]; tRNA aminoacylation for protein translation [GO:0006418]; vasculogenesis [GO:0001570] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830] 0.89043 -0.48958 LAVADAVIEK 0 0 0 0 0 0 0 0 0 9.08295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.1738 0 0 Q9UGN4 CLM8_HUMAN CMRF35-like molecule 8 (CLM-8) (CD300 antigen-like family member A) (CMRF-35-H9) (CMRF35-H9) (CMRF35-H) (IRC1/IRC2) (Immunoglobulin superfamily member 12) (IgSF12) (Inhibitory receptor protein 60) (IRp60) (NK inhibitory receptor) (CD antigen CD300a) CD300A CMRF35H IGSF12 HSPC083 Homo sapiens (Human) "cell adhesion [GO:0007155]; immune system process [GO:0002376]; negative regulation of activation of Janus kinase activity [GO:1902569]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of B cell receptor signaling pathway [GO:0050859]; negative regulation of eosinophil activation [GO:1902567]; negative regulation of eosinophil migration [GO:2000417]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of mast cell activation involved in immune response [GO:0033007]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of MyD88-dependent toll-like receptor signaling pathway [GO:0034125]; negative regulation of neutrophil activation [GO:1902564]; negative regulation of NK T cell activation [GO:0051134]; negative regulation of phagocytosis, engulfment [GO:0060101]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; regulation of T cell receptor signaling pathway [GO:0050856]" extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821] phosphatidylethanolamine binding [GO:0008429]; phosphatidylserine binding [GO:0001786]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888] 0.84794 0.15679 IAAQRPR 0 0 0 0 0 0 0 0 0 0 0 0 10.3697 10.6942 10.5181 0 0 0 0 0 0 0 0 0 0 0 0 Q9UGN5 PARP2_HUMAN Poly [ADP-ribose] polymerase 2 (PARP-2) (hPARP-2) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 2) (ARTD2) (DNA ADP-ribosyltransferase PARP2) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 2) (ADPRT-2) (Poly[ADP-ribose] synthase 2) (pADPRT-2) (Protein poly-ADP-ribosyltransferase PARP2) (EC 2.4.2.-) PARP2 ADPRT2 ADPRTL2 Homo sapiens (Human) base-excision repair [GO:0006284]; decidualization [GO:0046697]; DNA ADP-ribosylation [GO:0030592]; DNA damage response [GO:0006974]; DNA repair [GO:0006281]; DNA repair-dependent chromatin remodeling [GO:0140861]; double-strand break repair [GO:0006302]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of neuron death [GO:1901215]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; protein auto-ADP-ribosylation [GO:0070213]; protein poly-ADP-ribosylation [GO:0070212] nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of DNA damage [GO:0090734] chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+- protein-aspartate ADP-ribosyltransferase activity [GO:0140806]; NAD+-protein ADP-ribosyltransferase activity [GO:1990404]; NAD+-protein-glutamate ADP-ribosyltransferase activity [GO:0140807]; NAD+-protein-serine ADP-ribosyltransferase activity [GO:0140805]; nucleosome binding [GO:0031491]; nucleotidyltransferase activity [GO:0016779]; poly-ADP-D-ribose binding [GO:0072572]; poly-ADP-D-ribose modification-dependent protein binding [GO:0160004] 0.93034 -1.2355 TKNNWEDREK 0 0 0 0 0 0 0 0 0 0 9.41504 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UGP4 LIMD1_HUMAN LIM domain-containing protein 1 LIMD1 Homo sapiens (Human) cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; miRNA-mediated gene silencing [GO:0035195]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hippo signaling [GO:0035331]; negative regulation of osteoblast differentiation [GO:0045668]; osteoblast development [GO:0002076]; P-body assembly [GO:0033962]; phosphorylation [GO:0016310]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; regulation of cell shape [GO:0008360]; regulation of DNA-templated transcription [GO:0006355]; response to hypoxia [GO:0001666] adherens junction [GO:0005912]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; plasma membrane [GO:0005886]; RISC complex [GO:0016442]; transcription regulator complex [GO:0005667] metal ion binding [GO:0046872]; transcription corepressor activity [GO:0003714] 0.66092 0.39482 GPVNGGGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8196 10.7273 0 0 0 0 Q9UGP5 DPOLL_HUMAN DNA polymerase lambda (Pol Lambda) (EC 2.7.7.7) (EC 4.2.99.-) (DNA polymerase beta-2) (Pol beta2) (DNA polymerase kappa) POLL Homo sapiens (Human) "base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]" nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861] 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872] 0.37749 0.7246 AAQAFNSGLLCVACGSYRR 0 0 9.51045 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UGP8 SEC63_HUMAN Translocation protein SEC63 homolog SEC63 SEC63L Homo sapiens (Human) "liver development [GO:0001889]; nitrogen compound metabolic process [GO:0006807]; post-translational protein targeting to endoplasmic reticulum membrane [GO:0006620]; post-translational protein targeting to membrane, translocation [GO:0031204]; protein targeting to membrane [GO:0006612]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]" endoplasmic reticulum [GO:0005783]; membrane [GO:0016020]; Sec62/Sec63 complex [GO:0031207] protein transmembrane transporter activity [GO:0008320]; RNA binding [GO:0003723]; signaling receptor activity [GO:0038023] 0.96859 -3.929 AYAALTDEESR 0 12.5761 0 0 0 0 0 0 0 9.84372 0 10.5037 0 0 0 10.5537 0 0 0 0 0 0 0 0 0 0 0 Q9UGT4 SUSD2_HUMAN Sushi domain-containing protein 2 SUSD2 Homo sapiens (Human) negative regulation of cell cycle G1/S phase transition [GO:1902807]; negative regulation of cell division [GO:0051782] extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] 0.9538 -1.5226 VGALRIIDSK 9.68457 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UGU0 TCF20_HUMAN Transcription factor 20 (TCF-20) (Nuclear factor SPBP) (Protein AR1) (Stromelysin-1 PDGF-responsive element-binding protein) (SPRE-binding protein) TCF20 KIAA0292 SPBP Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872]; RNA binding [GO:0003723] 0.96939 -4.7085 DSSKDLPSPDSRNCPAVTLTSPAK 14.9212 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6188 0 0 0 0 0 0 0 0 0 0 Q9UH03 SEPT3_HUMAN Neuronal-specific septin-3 SEPTIN3 SEP3 SEPT3 Homo sapiens (Human) cytoskeleton-dependent cytokinesis [GO:0061640] cell division site [GO:0032153]; microtubule cytoskeleton [GO:0015630]; neuron projection [GO:0043005]; presynapse [GO:0098793]; presynaptic cytoskeleton [GO:0099569]; septin complex [GO:0031105]; septin ring [GO:0005940] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; molecular adaptor activity [GO:0060090] 0.96314 -2.659 EYQVNGKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.94727 0 0 0 0 0 0 0 0 0 Q9UH62 ARMX3_HUMAN Armadillo repeat-containing X-linked protein 3 (ARM protein lost in epithelial cancers on chromosome X 3) (Protein ALEX3) ARMCX3 ALEX3 BM-017 UNQ2517/PRO6007 Homo sapiens (Human) axonal transport of mitochondrion [GO:0019896]; mitochondrion organization [GO:0007005]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization [GO:0008104] axon cytoplasm [GO:1904115]; cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleus [GO:0005634] 0.91455 -0.82862 ARRAVQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4169 0 0 0 0 0 0 0 0 0 0 0 9.7881 Q9UH65 SWP70_HUMAN Switch-associated protein 70 (SWAP-70) SWAP70 KIAA0640 HSPC321 Homo sapiens (Human) actin filament bundle assembly [GO:0051017]; isotype switching [GO:0045190]; negative regulation of actin filament depolymerization [GO:0030835]; negative regulation of cell-cell adhesion mediated by integrin [GO:0033633]; negative regulation of peptidyl-serine dephosphorylation [GO:1902309]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of mast cell chemotaxis [GO:0060754]; regulation of protein localization [GO:0032880]; regulation of small GTPase mediated signal transduction [GO:0051056] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lamellipodium [GO:0030027]; nucleus [GO:0005634]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; guanyl-nucleotide exchange factor activity [GO:0005085] 0.88326 -0.26433 ELQAANESK 0 9.78387 0 0 0 0 0 10.9929 0 0 0 0 0 0 0 0 11.3422 0 0 0 0 0 0 0 0 0 0 Q9UH77 KLHL3_HUMAN Kelch-like protein 3 KLHL3 KIAA1129 Homo sapiens (Human) distal tubule morphogenesis [GO:0072156]; gene expression [GO:0010467]; monoatomic ion homeostasis [GO:0050801]; potassium ion homeostasis [GO:0055075]; protein K48-linked ubiquitination [GO:0070936]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; renal sodium ion absorption [GO:0070294]; selective autophagy [GO:0061912]; ubiquitin-dependent protein catabolic process [GO:0006511] Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoskeleton [GO:0005856]; cytosol [GO:0005829] actin binding [GO:0003779]; cullin family protein binding [GO:0097602]; structural molecule activity [GO:0005198] 0.3722 0.72743 AFKVMNELR 0 0 0 0 0 0 0 0 0 0 9.12601 0 0 0 0 0 0 0 0 0 0 0 0 0 9.53986 0 0 Q9UH90 FBX40_HUMAN F-box only protein 40 (Muscle disease-related protein) FBXO40 FBX40 KIAA1195 Homo sapiens (Human) muscle cell differentiation [GO:0042692] cytoplasm [GO:0005737]; cytosol [GO:0005829] ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.91482 -0.77764 MLIHFGQMPACTPKER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9074 0 0 Q9UH92 MLX_HUMAN Max-like protein X (Class D basic helix-loop-helix protein 13) (bHLHd13) (Max-like bHLHZip protein) (Protein BigMax) (Transcription factor-like protein 4) MLX BHLHD13 TCFL4 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.89654 -0.67473 GASLLSPK 0 0 0 0 0 0 0 11.5539 11.2766 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UH99 SUN2_HUMAN SUN domain-containing protein 2 (Protein unc-84 homolog B) (Rab5-interacting protein) (Rab5IP) (Sad1/unc-84 protein-like 2) SUN2 FRIGG KIAA0668 RAB5IP UNC84B Homo sapiens (Human) centrosome localization [GO:0051642]; meiotic cell cycle [GO:0051321]; mitotic spindle organization [GO:0007052]; nuclear matrix anchoring at nuclear membrane [GO:0090292]; nuclear migration [GO:0007097]; nuclear migration along microfilament [GO:0031022]; nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration [GO:0021817]; positive regulation of cell migration [GO:0030335] "chromosome, telomeric region [GO:0000781]; condensed nuclear chromosome [GO:0000794]; endosome membrane [GO:0010008]; meiotic nuclear membrane microtubule tethering complex [GO:0034993]; nuclear envelope [GO:0005635]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]" cytoskeleton-nuclear membrane anchor activity [GO:0140444]; identical protein binding [GO:0042802]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protein-membrane adaptor activity [GO:0043495] 0.96932 -3.3114 LSARIRPTAVTLEHVPK 0 0 0 0 0 0 0 0 0 0 0 0 7.89081 0 0 0 0 0 0 0 0 0 0 8.50255 0 8.86446 0 Q9UHA2 S18L2_HUMAN SS18-like protein 2 (SYT homolog 2) SS18L2 Homo sapiens (Human) transcription coactivator activity [GO:0003713] 0.95452 -1.5188 GKAEVNQETIQR 0 0 0 0 0 0 0 0 0 0 0 11.9145 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UHB6 LIMA1_HUMAN LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm) LIMA1 EPLIN SREBP3 PP624 Homo sapiens (Human) actin filament bundle assembly [GO:0051017]; cell migration [GO:0016477]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; intestinal cholesterol absorption [GO:0030299]; negative regulation of actin filament depolymerization [GO:0030835]; ruffle organization [GO:0031529] actin cytoskeleton [GO:0015629]; brush border membrane [GO:0031526]; cleavage furrow [GO:0032154]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stress fiber [GO:0001725] actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; cadherin binding [GO:0045296]; metal ion binding [GO:0046872] 0.96929 -4.942 ILRAQSR 0 0 0 0 0 0 8.4279 0 0 0 0 0 0 10.9456 0 0 0 0 9.20936 0 0 0 0 0 0 0 0 Q9UHB7 AFF4_HUMAN AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31 protein) (Protein AF-5q31) (Major CDK9 elongation factor-associated protein) AFF4 AF5Q31 MCEF HSPC092 Homo sapiens (Human) regulation of gene expression [GO:0010468]; response to endoplasmic reticulum stress [GO:0034976]; spermatid development [GO:0007286] euchromatin [GO:0000791]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; super elongation complex [GO:0032783]; transcription elongation factor complex [GO:0008023] 0.96767 -2.8922 HNADALSDRFEK 10.2908 9.79718 9.96212 10.1629 0 0 0 0 0 10.6334 10.4329 0 0 0 9.66375 9.27062 0 0 0 0 0 0 0 0 0 0 0 Q9UHB9 SRP68_HUMAN Signal recognition particle subunit SRP68 (SRP68) (Signal recognition particle 68 kDa protein) SRP68 Homo sapiens (Human) response to xenobiotic stimulus [GO:0009410]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614] "cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; focal adhesion [GO:0005925]; nucleolus [GO:0005730]; ribosome [GO:0005840]; signal recognition particle [GO:0048500]; signal recognition particle, endoplasmic reticulum targeting [GO:0005786]" 7S RNA binding [GO:0008312]; endoplasmic reticulum signal peptide binding [GO:0030942]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; signal recognition particle binding [GO:0005047] 0.88447 -0.14389 AVKHAEELERLCESNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3576 0 0 0 0 0 0 0 0 0 Q9UHC1 MLH3_HUMAN DNA mismatch repair protein Mlh3 (MutL protein homolog 3) MLH3 Homo sapiens (Human) female meiosis I [GO:0007144]; male meiotic nuclear division [GO:0007140]; mismatch repair [GO:0006298]; protein localization [GO:0008104]; reciprocal meiotic recombination [GO:0007131]; synaptonemal complex assembly [GO:0007130] chiasma [GO:0005712]; male germ cell nucleus [GO:0001673]; mismatch repair complex [GO:0032300]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; synaptonemal complex [GO:0000795] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent DNA damage sensor activity [GO:0140664]; centromeric DNA binding [GO:0019237]; chromatin binding [GO:0003682]; mismatched DNA binding [GO:0030983]; satellite DNA binding [GO:0003696] 0.96941 -5.898 ALKACEADVTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6456 0 0 0 0 0 0 0 0 0 0 Q9UHC3 ASIC3_HUMAN Acid-sensing ion channel 3 (ASIC3) (hASIC3) (Amiloride-sensitive cation channel 3) (Neuronal amiloride-sensitive cation channel 3) (Testis sodium channel 1) (hTNaC1) ASIC3 ACCN3 SLNAC1 TNAC1 Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; sensory perception [GO:0007600]; sensory perception of sour taste [GO:0050915]; signal transduction [GO:0007165]; sodium ion transmembrane transport [GO:0035725] perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] acid-sensing ion channel activity [GO:0044736]; enterobactin transmembrane transporter activity [GO:0042931]; monoatomic cation channel activity [GO:0005261]; sodium channel activity [GO:0005272] 0.84962 0.12037 MVYMPGDVPVCSPQQYK 0 0 0 0 0 0 9.21515 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UHC6 CNTP2_HUMAN Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) CNTNAP2 CASPR2 KIAA0868 Homo sapiens (Human) adult behavior [GO:0030534]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; clustering of voltage-gated potassium channels [GO:0045163]; learning [GO:0007612]; limbic system development [GO:0021761]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; positive regulation of gap junction assembly [GO:1903598]; protein localization to juxtaparanode region of axon [GO:0071205]; social behavior [GO:0035176]; striatum development [GO:0021756]; superior temporal gyrus development [GO:0071109]; thalamus development [GO:0021794]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625] axolemma [GO:0030673]; axon [GO:0030424]; cell surface [GO:0009986]; dendrite [GO:0030425]; early endosome [GO:0005769]; Golgi apparatus [GO:0005794]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; voltage-gated potassium channel complex [GO:0008076] enzyme binding [GO:0019899] 0.9198 -0.90794 FSFSTTK 0 11.1396 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.048 0 0 0 0 0 0 0 Q9UHC7 MKRN1_HUMAN E3 ubiquitin-protein ligase makorin-1 (EC 2.3.2.27) (RING finger protein 61) (RING-type E3 ubiquitin transferase makorin-1) MKRN1 RNF61 Homo sapiens (Human) protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567] cytosol [GO:0005829] metal ion binding [GO:0046872]; RNA binding [GO:0003723]; ubiquitin protein ligase activity [GO:0061630] 0.96713 -2.3307 SKDMVCGICMEVVYEK 0 10.2178 0 0 0 0 0 0 0 9.97957 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UHC9 NPCL1_HUMAN NPC1-like intracellular cholesterol transporter 1 (NPC1L1) (Niemann-Pick C1-like protein 1) NPC1L1 Homo sapiens (Human) cellular response to sterol depletion [GO:0071501]; cholesterol biosynthetic process [GO:0006695]; cholesterol homeostasis [GO:0042632]; cholesterol transport [GO:0030301]; intestinal cholesterol absorption [GO:0030299]; lipoprotein metabolic process [GO:0042157]; vitamin E metabolic process [GO:0042360]; vitamin transport [GO:0051180] apical plasma membrane [GO:0016324]; cytoplasmic vesicle membrane [GO:0030659]; plasma membrane [GO:0005886] cholesterol binding [GO:0015485]; myosin V binding [GO:0031489]; protein homodimerization activity [GO:0042803]; small GTPase binding [GO:0031267]; vitamin E binding [GO:0008431] 0.91959 -0.8909 DKSKMVDPK 0 0 0 0 0 0 0 0 0 9.10087 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UHD0 IL19_HUMAN Interleukin-19 (IL-19) (Melanoma differentiation-associated protein-like protein) (NG.1) IL19 ZMDA1 Homo sapiens (Human) apoptotic process [GO:0006915]; immune response [GO:0006955]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; reactive oxygen species metabolic process [GO:0072593]; signal transduction [GO:0007165] extracellular region [GO:0005576]; extracellular space [GO:0005615] cytokine activity [GO:0005125] 0.88116 -0.30228 VFKDHQEPNPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.45953 0 0 0 0 0 0 0 0 0 0 Q9UHD8 SEPT9_HUMAN Septin-9 (MLL septin-like fusion protein MSF-A) (MLL septin-like fusion protein) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1) SEPTIN9 KIAA0991 MSF SEPT9 Homo sapiens (Human) cytoskeleton-dependent cytokinesis [GO:0061640]; positive regulation of non-motile cilium assembly [GO:1902857] actin cytoskeleton [GO:0015629]; axoneme [GO:0005930]; cell division site [GO:0032153]; cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; non-motile cilium [GO:0097730]; perinuclear region of cytoplasm [GO:0048471]; septin complex [GO:0031105]; septin ring [GO:0005940]; stress fiber [GO:0001725] cadherin binding [GO:0045296]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; molecular adaptor activity [GO:0060090] 0.0057307 2.3044 ADTLTLEER 0 0 0 9.17038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UHF4 I20RA_HUMAN Interleukin-20 receptor subunit alpha (IL-20 receptor subunit alpha) (IL-20R-alpha) (IL-20RA) (Cytokine receptor class-II member 8) (Cytokine receptor family 2 member 8) (CRF2-8) (IL-20R1) (ZcytoR7) IL20RA UNQ681/PRO1315 Homo sapiens (Human) cytokine-mediated signaling pathway [GO:0019221]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; regulation of bone resorption [GO:0045124] plasma membrane [GO:0005886] interleukin-20 binding [GO:0042015] 0.88543 -0.24155 TLKDQSSEFK 0 0 0 0 0 0 0 0 0 0 0 0 10.2275 0 0 10.9037 0 0 0 0 0 0 0 0 0 0 0 Q9UHF7 TRPS1_HUMAN Zinc finger transcription factor Trps1 (Tricho-rhino-phalangeal syndrome type I protein) (Zinc finger protein GC79) TRPS1 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of chondrocyte differentiation [GO:0032330]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; protein domain specific binding [GO:0019904]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; zinc ion binding [GO:0008270]" 0.045259 1.4594 QNNGEQIIRR 0 0 0 9.95671 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.76633 0 0 0 0 0 0 0 Q9UHG0 DCDC2_HUMAN Doublecortin domain-containing protein 2 (Protein RU2S) DCDC2 KIAA1154 RU2 Homo sapiens (Human) cellular defense response [GO:0006968]; cilium assembly [GO:0060271]; dendrite morphogenesis [GO:0048813]; intracellular signal transduction [GO:0035556]; neuron migration [GO:0001764]; positive regulation of smoothened signaling pathway [GO:0045880]; regulation of cilium assembly [GO:1902017]; regulation of Wnt signaling pathway [GO:0030111]; sensory perception of sound [GO:0007605] axoneme [GO:0005930]; centriolar satellite [GO:0034451]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinocilium [GO:0060091]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; microtubule organizing center [GO:0005815]; mitotic spindle [GO:0072686] kinesin binding [GO:0019894] 0.93003 -1.2437 GKKEDVNSEK 0 0 0 0 0 0 0 0 0 0 9.68294 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UHH9 IP6K2_HUMAN Inositol hexakisphosphate kinase 2 (InsP6 kinase 2) (InsP6K2) (EC 2.7.4.-) (P(i)-uptake stimulator) (PiUS) IP6K2 IHPK2 TCCCIA00113 Homo sapiens (Human) cellular response to flavonoid [GO:1905396]; inositol phosphate biosynthetic process [GO:0032958]; inositol phosphate metabolic process [GO:0043647]; negative regulation of cell growth [GO:0030308]; phosphate ion transport [GO:0006817]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; phosphorylation [GO:0016310]; positive regulation of apoptotic process [GO:0043065]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; protein stabilization [GO:0050821] cell junction [GO:0030054]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "ATP binding [GO:0005524]; flavonoid binding [GO:0097243]; inositol 5-diphosphate pentakisphosphate 5-kinase activity [GO:0052836]; inositol diphosphate tetrakisphosphate kinase activity [GO:0052839]; inositol heptakisphosphate kinase activity [GO:0000829]; inositol hexakisphosphate 5-kinase activity [GO:0000832]; inositol hexakisphosphate kinase activity [GO:0000828]; inositol-1,3,4,5,6-pentakisphosphate kinase activity [GO:0000827]" 0.9516 -1.4295 EHQFYETLPAEMRKFTPQYK 0 0 0 0 0 0 0 0 0 0 11.7557 0 0 0 0 0 0 0 0 0 8.79912 0 0 0 0 0 0 Q9UHI5 LAT2_HUMAN Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2) (hLAT2) (Solute carrier family 7 member 8) SLC7A8 LAT2 Homo sapiens (Human) amino acid import across plasma membrane [GO:0089718]; amino acid transmembrane transport [GO:0003333]; amino acid transport [GO:0006865]; glycine transport [GO:0015816]; L-alanine import across plasma membrane [GO:1904273]; L-leucine import across plasma membrane [GO:1903801]; leucine import across plasma membrane [GO:0098713]; leucine transport [GO:0015820]; neutral amino acid transport [GO:0015804]; proline transmembrane transport [GO:0035524]; thyroid hormone transport [GO:0070327]; transport across blood-brain barrier [GO:0150104]; tryptophan transport [GO:0015827]; valine transport [GO:0015829] apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytoplasm [GO:0005737]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886] amino acid transmembrane transporter activity [GO:0015171]; glycine transmembrane transporter activity [GO:0015187]; L-alanine transmembrane transporter activity [GO:0015180]; L-amino acid transmembrane transporter activity [GO:0015179]; L-leucine transmembrane transporter activity [GO:0015190]; neutral L-amino acid transmembrane transporter activity [GO:0015175]; organic cation transmembrane transporter activity [GO:0015101]; peptide antigen binding [GO:0042605]; thyroid hormone transmembrane transporter activity [GO:0015349]; toxin transmembrane transporter activity [GO:0019534] 0.33631 0.77294 EEGARHR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.73993 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UHI6 DDX20_HUMAN Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.15) (EC 3.6.4.13) (Component of gems 3) (DEAD box protein 20) (DEAD box protein DP 103) (Gemin-3) DDX20 DP103 GEMIN3 Homo sapiens (Human) negative regulation of cell population proliferation [GO:0008285]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oogenesis [GO:0048477]; positive regulation of apoptotic process [GO:0043065]; regulation of steroid biosynthetic process [GO:0050810]; RNA processing [GO:0006396]; spliceosomal snRNP assembly [GO:0000387]; spliceosomal tri-snRNP complex assembly [GO:0000244] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; Gemini of coiled bodies [GO:0097504]; membrane [GO:0016020]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription repressor complex [GO:0090571]; SMN complex [GO:0032797]; SMN-Sm protein complex [GO:0034719] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; DNA binding [GO:0003677]; DNA-binding transcription factor binding [GO:0140297]; histone deacetylase binding [GO:0042826]; protein domain specific binding [GO:0019904]; protein-macromolecule adaptor activity [GO:0030674]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.96877 -3.014 EGASQRAKQSR 0 0 0 0 0 0 0 0 0 8.99059 8.73407 0 0 0 0 0 0 0 0 0 10.3046 0 9.73552 0 10.9106 0 0 Q9UHI7 S23A1_HUMAN Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1) (hSVCT1) (Yolk sac permease-like molecule 3) SLC23A1 SVCT1 YSPL3 Homo sapiens (Human) brain development [GO:0007420]; dehydroascorbic acid transport [GO:0070837]; L-ascorbic acid metabolic process [GO:0019852]; L-ascorbic acid transmembrane transport [GO:0015882]; lung development [GO:0030324]; nucleobase transport [GO:0015851]; response to toxic substance [GO:0009636]; sodium ion transport [GO:0006814] apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; brush border [GO:0005903]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; intracellular organelle [GO:0043229]; plasma membrane [GO:0005886] dehydroascorbic acid transmembrane transporter activity [GO:0033300]; L-ascorbate:sodium symporter activity [GO:0008520]; L-ascorbic acid transmembrane transporter activity [GO:0015229]; nucleobase transmembrane transporter activity [GO:0015205]; sodium ion transmembrane transporter activity [GO:0015081] 0.87056 0.052522 AGAHANSDMSSSLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.14106 Q9UHI8 ATS1_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAM-TS 1) (ADAM-TS1) (ADAMTS-1) (EC 3.4.24.-) (METH-1) ADAMTS1 KIAA1346 METH1 Homo sapiens (Human) extracellular matrix organization [GO:0030198]; heart trabecula formation [GO:0060347]; integrin-mediated signaling pathway [GO:0007229]; kidney development [GO:0001822]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell population proliferation [GO:0008285]; ovulation from ovarian follicle [GO:0001542]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508] basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576] heparin binding [GO:0008201]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270] 0.91399 -0.82554 EEQCEAHNEFSK 11.702 0 0 0 0 0 11.9198 11.7889 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.89715 Q9UHJ3 SMBT1_HUMAN Scm-like with four MBT domains protein 1 (hSFMBT) (Renal ubiquitous protein 1) SFMBT1 RU1 Homo sapiens (Human) cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of muscle organ development [GO:0048635]; spermatogenesis [GO:0007283] nucleoplasm [GO:0005654]; nucleus [GO:0005634] histone binding [GO:0042393]; transcription corepressor activity [GO:0003714] 0.9537 -1.499 HLKNEAEWQEILAK 0 0 0 0 0 0 0 0 0 8.99215 0 0 0 0 10.0077 0 0 0 0 0 0 0 0 0 0 0 0 Q9UHK0 NUFP1_HUMAN FMR1-interacting protein NUFIP1 (Nuclear FMR1-interacting protein 1) (Nuclear FMRP-interacting protein 1) NUFIP1 Homo sapiens (Human) box C/D snoRNP assembly [GO:0000492]; positive regulation of transcription by RNA polymerase II [GO:0045944]; RNA processing [GO:0006396] fibrillar center [GO:0001650]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perichromatin fibrils [GO:0005726]; pre-snoRNP complex [GO:0070761]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; transcription elongation factor complex [GO:0008023] ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein-macromolecule adaptor activity [GO:0030674]; RNA binding [GO:0003723] 0.95483 -1.5201 GMSRHSQMAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.44969 0 0 0 0 Q9UHK6 AMACR_HUMAN Alpha-methylacyl-CoA racemase (EC 5.1.99.4) (2-methylacyl-CoA racemase) AMACR Homo sapiens (Human) bile acid biosynthetic process [GO:0006699]; bile acid metabolic process [GO:0008206]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540] cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; plasma membrane [GO:0005886] alpha-methylacyl-CoA racemase activity [GO:0008111]; signaling receptor binding [GO:0005102] 0.91609 -0.77178 GVMEKLQLGPEILQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14.9726 0 0 0 0 0 0 0 0 0 0 0 Q9UHL3 F153A_HUMAN Protein FAM153A (Renal carcinoma antigen NY-REN-7) FAM153A KIAA0752 Homo sapiens (Human) 0.79556 0.24352 ELHLYSTWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.6024 0 0 0 0 0 0 0 0 0 0 Q9UHL4 DPP2_HUMAN Dipeptidyl peptidase 2 (EC 3.4.14.2) (Dipeptidyl aminopeptidase II) (Dipeptidyl peptidase 7) (Dipeptidyl peptidase II) (DPP II) (Quiescent cell proline dipeptidase) DPP7 DPP2 QPP Homo sapiens (Human) lysosomal protein catabolic process [GO:1905146]; proteolysis [GO:0006508] azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; vesicle [GO:0031982] aminopeptidase activity [GO:0004177]; dipeptidyl-peptidase activity [GO:0008239]; serine-type peptidase activity [GO:0008236] 0.89873 -0.66483 DVTADFEGQSPK 0 0 0 0 0 0 0 0 0 0 10.1454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.10292 0 Q9UHL9 GT2D1_HUMAN General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (General transcription factor III) (MusTRD1/BEN) (Muscle TFII-I repeat domain-containing protein 1) (Slow-muscle-fiber enhancer-binding protein) (USE B1-binding protein) (Williams-Beuren syndrome chromosomal region 11 protein) (Williams-Beuren syndrome chromosomal region 12 protein) GTF2IRD1 CREAM1 GTF3 MUSTRD1 RBAP2 WBSCR11 WBSCR12 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355]; transcription by RNA polymerase II [GO:0006366]; transition between slow and fast fiber [GO:0014886] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.95973 -1.8135 AIGISEPVK 0 0 11.7195 0 0 0 0 0 0 0 0 0 8.91004 0 0 0 10.3809 0 10.3585 0 0 0 0 0 0 9.97039 11.2638 Q9UHM6 OPN4_HUMAN Melanopsin (Opsin-4) OPN4 MOP Homo sapiens (Human) detection of temperature stimulus involved in thermoception [GO:0050960]; G protein-coupled receptor signaling pathway [GO:0007186]; hyaloid vascular plexus regression [GO:1990384]; optokinetic behavior [GO:0007634]; phototransduction [GO:0007602]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; thermotaxis [GO:0043052]; visual perception [GO:0007601] axon [GO:0030424]; dendrite [GO:0030425]; membrane [GO:0016020]; perikaryon [GO:0043204]; photoreceptor disc membrane [GO:0097381]; plasma membrane [GO:0005886]; sperm head plasma membrane [GO:1990913] 11-cis retinal binding [GO:0005502]; G protein-coupled photoreceptor activity [GO:0008020] 0.87729 -0.0056403 GLIPSQDPR 0 0 0 0 0 0 0 0 0 8.94924 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UHP3 UBP25_HUMAN Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.4.19.12) (Deubiquitinating enzyme 25) (USP on chromosome 21) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) USP25 USP21 Homo sapiens (Human) negative regulation of ERAD pathway [GO:1904293]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; protein modification process [GO:0036211]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647]; ubiquitin-dependent protein catabolic process [GO:0006511] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634] ATPase binding [GO:0051117]; cysteine-type deubiquitinase activity [GO:0004843]; cysteine-type endopeptidase activity [GO:0004197]; peptidase activity [GO:0008233]; SUMO binding [GO:0032183]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein peptidase activity [GO:0019783] 0.55923 0.53595 ESYIDSLLFLICAYQNNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0433 0 0 0 0 10.7663 10.1477 0 Q9UHP7 CLC2D_HUMAN C-type lectin domain family 2 member D (Lectin-like NK cell receptor) (Lectin-like transcript 1) (LLT-1) (Osteoclast inhibitory lectin) CLEC2D CLAX LLT1 OCIL Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166] cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; membrane [GO:0016020]; plasma membrane [GO:0005886] carbohydrate binding [GO:0030246]; transmembrane signaling receptor activity [GO:0004888] 0.88784 -0.40149 EQGQPWKWINGTEWTR 0 0 0 0 0 0 0 0 0 10.1434 0 0 0 0 0 11.5417 0 0 0 0 0 8.1875 0 0 0 0 0 Q9UHQ1 NARF_HUMAN Nuclear prelamin A recognition factor (Iron-only hydrogenase-like protein 2) (IOP2) NARF Homo sapiens (Human) lamin filament [GO:0005638]; nuclear lamina [GO:0005652]; nuclear lumen [GO:0031981]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] lamin binding [GO:0005521] 0.92993 -1.244 ELFNEDVEEVTYRALRNK 0 0 0 10.8338 0 0 0 0 0 9.66947 0 0 11.295 0 10.9898 0 0 10.9003 0 0 0 0 0 0 0 0 0 Q9UHQ7 TCAL9_HUMAN Transcription elongation factor A protein-like 9 (TCEA-like protein 9) (Transcription elongation factor S-II protein-like 9) (WW domain-binding protein 5) (WBP-5) TCEAL9 WBP5 Homo sapiens (Human) nucleus [GO:0005634] 0.91781 -0.86342 HEEEPKPEEKPEEEEKLEEEAK 0 0 9.04004 0 0 0 0 0 0 0 0 9.10024 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UHR4 BI2L1_HUMAN Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1) (Insulin receptor tyrosine kinase substrate) BAIAP2L1 IRTKS Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin filament bundle assembly [GO:0051017]; plasma membrane organization [GO:0007009]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; regulation of actin cytoskeleton organization [GO:0032956] adherens junction [GO:0005912]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] actin binding [GO:0003779]; cadherin binding involved in cell-cell adhesion [GO:0098641]; proline-rich region binding [GO:0070064] 0.91827 -0.88331 LNESLDENFKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16.4619 0 10.3836 0 0 0 0 0 0 0 Q9UHR5 S30BP_HUMAN SAP30-binding protein (Transcriptional regulator protein HCNGP) SAP30BP HCNGP HTRG HTRP Homo sapiens (Human) modulation by host of symbiont transcription [GO:0052472]; regulation of DNA-templated transcription [GO:0006355]; response to virus [GO:0009615] intermediate filament cytoskeleton [GO:0045111]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.60465 0.4368 DMFDPHGWSEDSYYEALAK 0 9.74619 0 0 0 0 0 0 0 0 0 9.26336 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UHR6 ZNHI2_HUMAN Zinc finger HIT domain-containing protein 2 (Protein FON) ZNHIT2 C11orf5 Homo sapiens (Human) metal ion binding [GO:0046872] 0.80288 0.23782 GPVSPLVR 0 0 0 0 0 0 0 0 0 0 0 15.0887 0 0 0 0 12.8605 0 0 11.9583 0 0 0 0 0 12.7068 12.6152 Q9UHV5 RPGFL_HUMAN Rap guanine nucleotide exchange factor-like 1 (Link guanine nucleotide exchange factor II) (Link GEFII) RAPGEFL1 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; nervous system development [GO:0007399]; positive regulation of GTPase activity [GO:0043547]; Ras protein signal transduction [GO:0007265] membrane [GO:0016020]; plasma membrane [GO:0005886] guanyl-nucleotide exchange factor activity [GO:0005085] 0.95282 -1.4932 LHSVAEKVRTIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.17854 0 9.88347 0 0 0 0 0 0 0 0 11.1301 Q9UHV7 MED13_HUMAN Mediator of RNA polymerase II transcription subunit 13 (Activator-recruited cofactor 250 kDa component) (ARC250) (Mediator complex subunit 13) (Thyroid hormone receptor-associated protein 1) (Thyroid hormone receptor-associated protein complex 240 kDa component) (Trap240) (Vitamin D3 receptor-interacting protein complex component DRIP250) (DRIP250) MED13 ARC250 KIAA0593 THRAP1 TRAP240 Homo sapiens (Human) cholesterol homeostasis [GO:0042632]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; triglyceride homeostasis [GO:0070328] mediator complex [GO:0016592]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] nuclear receptor coactivator activity [GO:0030374]; nuclear thyroid hormone receptor binding [GO:0046966]; nuclear vitamin D receptor binding [GO:0042809]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712] 0.96199 -2.5603 VGSTASK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.16022 0 0 0 0 0 0 0 0 0 0 Q9UHV9 PFD2_HUMAN Prefoldin subunit 2 PFDN2 PFD2 HSPC231 Homo sapiens (Human) negative regulation of amyloid fibril formation [GO:1905907]; positive regulation of cytoskeleton organization [GO:0051495]; protein folding [GO:0006457]; protein stabilization [GO:0050821] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; prefoldin complex [GO:0016272]; protein folding chaperone complex [GO:0101031]; RPAP3/R2TP/prefoldin-like complex [GO:1990062] amyloid-beta binding [GO:0001540]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082] 0.76012 0.29533 GAVSAEQVIAGFNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3061 0 0 0 0 0 0 0 Q9UHW9 S12A6_HUMAN Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3) SLC12A6 KCC3 Homo sapiens (Human) ammonium import across plasma membrane [GO:0140157]; angiogenesis [GO:0001525]; cell volume homeostasis [GO:0006884]; cellular hypotonic response [GO:0071476]; cellular hypotonic salinity response [GO:0071477]; cellular response to glucose stimulus [GO:0071333]; chemical synaptic transmission [GO:0007268]; chloride ion homeostasis [GO:0055064]; chloride transmembrane transport [GO:1902476]; monoatomic ion transport [GO:0006811]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805] axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; membrane [GO:0016020]; plasma membrane [GO:0005886]; synapse [GO:0045202] ammonium transmembrane transporter activity [GO:0008519]; potassium ion transmembrane transporter activity [GO:0015079]; potassium:chloride symporter activity [GO:0015379]; protein kinase binding [GO:0019901] 0.88387 -0.29897 LDEDLHVKHPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.68766 0 0 0 0 0 0 0 0 0 0 0 0 Q9UHX1 PUF60_HUMAN Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor) (FUSE-binding protein-interacting repressor) (FBP-interacting repressor) (Ro-binding protein 1) (RoBP1) (Siah-binding protein 1) (Siah-BP1) PUF60 FIR ROBPI SIAHBP1 Homo sapiens (Human) "alternative mRNA splicing, via spliceosome [GO:0000380]; apoptotic process [GO:0006915]; mRNA splice site selection [GO:0006376]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]" cell junction [GO:0030054]; nucleoplasm [GO:0005654]; ribonucleoprotein complex [GO:1990904] cadherin binding [GO:0045296]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; RNA binding [GO:0003723] 0.56219 0.5095 QAFAPFGPIK 0 0 0 0 0 10.3821 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UHY8 FEZ2_HUMAN Fasciculation and elongation protein zeta-2 (Zygin II) (Zygin-2) FEZ2 Homo sapiens (Human) axon guidance [GO:0007411]; negative regulation of autophagosome assembly [GO:1902902]; nervous system development [GO:0007399]; signal transduction [GO:0007165] axon [GO:0030424]; cytoplasm [GO:0005737] 0.6846 0.38958 LKNGSSQNGKNER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.82498 0 0 0 Q9UI10 EI2BD_HUMAN Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta) EIF2B4 EIF2BD Homo sapiens (Human) myelination [GO:0042552]; oligodendrocyte development [GO:0014003]; ovarian follicle development [GO:0001541]; regulation of translation [GO:0006417]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to peptide hormone [GO:0043434]; T cell receptor signaling pathway [GO:0050852]; translational initiation [GO:0006413] cytoplasm [GO:0005737]; cytosol [GO:0005829]; eukaryotic translation initiation factor 2B complex [GO:0005851] translation initiation factor activity [GO:0003743]; translation initiation factor binding [GO:0031369] 0.49609 0.61586 ILQEAWTEGRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.71524 0 0 0 0 0 Q9UI12 VATH_HUMAN V-type proton ATPase subunit H (V-ATPase subunit H) (Nef-binding protein 1) (NBP1) (Protein VMA13 homolog) (V-ATPase 50/57 kDa subunits) (Vacuolar proton pump subunit H) (Vacuolar proton pump subunit SFD) ATP6V1H CGI-11 Homo sapiens (Human) endocytosis [GO:0006897]; endosomal lumen acidification [GO:0048388]; Golgi lumen acidification [GO:0061795]; intracellular pH reduction [GO:0051452]; lysosomal lumen acidification [GO:0007042]; proton transmembrane transport [GO:1902600]; regulation of macroautophagy [GO:0016241]; synaptic vesicle lumen acidification [GO:0097401]; vacuolar acidification [GO:0007035] "clathrin-coated vesicle membrane [GO:0030665]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; proton-transporting V-type ATPase complex [GO:0033176]; transmembrane transporter complex [GO:1902495]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]" "enzyme regulator activity [GO:0030234]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]" 0.92366 -1.0189 FEMKRSPEEK 0 0 0 0 0 0 0 0 0 0 0 0 9.40667 0 0 0 0 11.497 0 0 9.76962 0 0 10.5097 0 0 0 Q9UI14 PRAF1_HUMAN Prenylated Rab acceptor protein 1 (PRA1 family protein 1) RABAC1 PRA1 PRAF1 Homo sapiens (Human) Golgi apparatus [GO:0005794]; membrane [GO:0016020]; plasma membrane [GO:0005886]; synaptic vesicle [GO:0008021] GTPase binding [GO:0051020]; identical protein binding [GO:0042802]; proline-rich region binding [GO:0070064] 0.19025 0.93931 DAEAEGLSGTTLLPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.82381 Q9UI17 M2GD_HUMAN "Dimethylglycine dehydrogenase, mitochondrial (EC 1.5.8.4) (ME2GLYDH)" DMGDH Homo sapiens (Human) amino-acid betaine catabolic process [GO:0006579]; choline catabolic process [GO:0042426]; choline metabolic process [GO:0019695] cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] dimethylglycine dehydrogenase activity [GO:0047865]; electron transfer activity [GO:0009055]; RNA binding [GO:0003723] 0.93393 -1.2807 IHYDSIKLYEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.50506 0 0 0 0 0 0 0 0 Q9UI26 IPO11_HUMAN Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11) IPO11 RANBP11 Homo sapiens (Human) protein import into nucleus [GO:0006606]; ribosomal protein import into nucleus [GO:0006610] cytosol [GO:0005829]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654] nuclear import signal receptor activity [GO:0061608]; small GTPase binding [GO:0031267] 0.94855 -1.3617 SIGTDNVCR 0 0 0 0 0 0 0 0 0 0 0 9.50635 0 0 0 0 0 0 10.0674 0 0 0 0 0 0 0 0 Q9UI30 TR112_HUMAN Multifunctional methyltransferase subunit TRM112-like protein (tRNA methyltransferase 112 homolog) TRMT112 AD-001 HSPC152 HSPC170 Homo sapiens (Human) peptidyl-glutamine methylation [GO:0018364]; positive regulation of rRNA processing [GO:2000234]; rRNA (guanine-N7)-methylation [GO:0070476]; rRNA methylation [GO:0031167]; transcription initiation-coupled chromatin remodeling [GO:0045815]; tRNA methylation [GO:0030488]; tRNA N2-guanine methylation [GO:0002940] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991] protein heterodimerization activity [GO:0046982]; protein methyltransferase activity [GO:0008276] 0.91341 -0.78594 ICPVEFNPNFVARMIPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0542 0 0 0 Q9UI32 GLSL_HUMAN "Glutaminase liver isoform, mitochondrial (GLS) (EC 3.5.1.2) (L-glutaminase) (L-glutamine amidohydrolase)" GLS2 GA Homo sapiens (Human) amino acid metabolic process [GO:0006520]; glutamate biosynthetic process [GO:0006537]; glutamine catabolic process [GO:0006543]; reactive oxygen species metabolic process [GO:0072593]; regulation of apoptotic process [GO:0042981] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] glutaminase activity [GO:0004359] 0.95394 -1.5003 EPSGLRYNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.4015 0 0 0 0 0 0 0 0 0 0 Q9UI33 SCNBA_HUMAN Sodium channel protein type 11 subunit alpha (Peripheral nerve sodium channel 5) (PN5) (Sensory neuron sodium channel 2) (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (hNaN) SCN11A SCN12A SNS2 Homo sapiens (Human) action potential initiation [GO:0099610]; acute inflammatory response [GO:0002526]; artery development [GO:0060840]; axonogenesis [GO:0007409]; behavioral response to acetic acid induced pain [GO:0061367]; behavioral response to formalin induced pain [GO:0061368]; calcitonin gene-related peptide receptor signaling pathway [GO:1990408]; calcium ion import across plasma membrane [GO:0098703]; cell motility [GO:0048870]; cellular response to cold [GO:0070417]; chronic inflammatory response [GO:0002544]; circadian rhythm [GO:0007623]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; mast cell degranulation [GO:0043303]; micturition [GO:0060073]; neuronal action potential [GO:0019228]; protein kinase A signaling [GO:0010737]; reflex [GO:0060004]; regulation of monoatomic ion transmembrane transport [GO:0034765]; regulation of sensory perception of pain [GO:0051930]; response to auditory stimulus [GO:0010996]; response to heat [GO:0009408]; response to high light intensity [GO:0009644]; response to nitric oxide [GO:0071731]; response to prostaglandin E [GO:0034695]; response to toxic substance [GO:0009636]; response to xenobiotic stimulus [GO:0009410]; sensory perception of itch [GO:0160025]; skeletal muscle organ development [GO:0060538]; small intestine smooth muscle contraction [GO:1990770]; sodium ion transport [GO:0006814]; thermosensory behavior [GO:0040040]; thigmotaxis [GO:0001966] axon [GO:0030424]; axonal growth cone [GO:0044295]; C-fiber [GO:0044299]; extracellular exosome [GO:0070062]; neuronal cell body [GO:0043025]; voltage-gated calcium channel complex [GO:0005891]; voltage-gated sodium channel complex [GO:0001518] high voltage-gated calcium channel activity [GO:0008331]; voltage-gated sodium channel activity [GO:0005248] 0.90624 -0.71491 ALSQFEGMK 0 0 0 0 0 0 0 0 0 0 0 10.8211 0 10.1389 0 0 10.5814 0 0 0 0 0 0 0 0 0 0 Q9UI40 NCKX2_HUMAN Sodium/potassium/calcium exchanger 2 (Na(+)/K(+)/Ca(2+)-exchange protein 2) (Retinal cone Na-Ca+K exchanger) (Solute carrier family 24 member 2) SLC24A2 NCKX2 Homo sapiens (Human) calcium ion import [GO:0070509]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; cellular response to high light intensity [GO:0071486]; cone photoresponse recovery [GO:0036368]; establishment of localization in cell [GO:0051649]; intracellular calcium ion homeostasis [GO:0006874]; learning [GO:0007612]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; monoatomic ion transmembrane transport [GO:0034220]; monoatomic ion transport [GO:0006811]; neuron cellular homeostasis [GO:0070050]; phototransduction [GO:0007602]; potassium ion transmembrane transport [GO:0071805]; sodium ion transmembrane transport [GO:0035725] photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886] "calcium channel activity [GO:0005262]; calcium, potassium:sodium antiporter activity [GO:0008273]; symporter activity [GO:0015293]" 0.9509 -1.3838 DIFSLEER 0 0 0 0 0 0 0 0 0 0 0 8.02547 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UI42 CBPA4_HUMAN Carboxypeptidase A4 (EC 3.4.17.-) (Carboxypeptidase A3) CPA4 CPA3 UNQ694/PRO1339 Homo sapiens (Human) histone acetylation [GO:0016573]; proteolysis [GO:0006508] extracellular space [GO:0005615] metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270] 0.95465 -1.5071 LSQLVNSNNLKLNFWK 0 0 0 0 0 0 0 9.26365 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UI43 MRM2_HUMAN "rRNA methyltransferase 2, mitochondrial (EC 2.1.1.-) (16S rRNA (uridine(1369)-2'-O)-methyltransferase) (16S rRNA [Um1369] 2'-O-methyltransferase) (Protein ftsJ homolog 2)" MRM2 FJH1 FTSJ2 Homo sapiens (Human) mitochondrial large ribosomal subunit assembly [GO:1902775]; RNA methylation [GO:0001510]; rRNA 2'-O-methylation [GO:0000451]; rRNA methylation [GO:0031167]; rRNA processing [GO:0006364] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730] rRNA (uridine-2'-O-)-methyltransferase activity [GO:0008650] 0.3567 0.75344 LVCVSFQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4095 0 0 0 Q9UI46 DNAI1_HUMAN Dynein axonemal intermediate chain 1 (Axonemal dynein intermediate chain 1) DNAI1 Homo sapiens (Human) cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; insulin receptor signaling pathway [GO:0008286]; outer dynein arm assembly [GO:0036158] 9+2 motile cilium [GO:0097729]; centrosome [GO:0005813]; cilium [GO:0005929]; cytoskeleton [GO:0005856]; dynein axonemal particle [GO:0120293]; extracellular region [GO:0005576]; microtubule [GO:0005874]; outer dynein arm [GO:0036157] cytoskeletal motor activity [GO:0003774]; dynein heavy chain binding [GO:0045504]; dynein light chain binding [GO:0045503] 0.91404 -0.82047 IWDHTIK 0 11.3931 0 11.703 0 0 0 12.7585 0 10.1698 0 12.3111 11.8298 0 0 0 0 12.4742 0 0 0 0 0 0 0 0 0 Q9UIA9 XPO7_HUMAN Exportin-7 (Exp7) (Ran-binding protein 16) XPO7 KIAA0745 RANBP16 Homo sapiens (Human) protein export from nucleus [GO:0006611] cytoplasm [GO:0005737]; nuclear pore [GO:0005643]; nucleus [GO:0005634] nuclear export signal receptor activity [GO:0005049]; small GTPase binding [GO:0031267] 0.9515 -1.4297 ALVEFTNSPDCLSK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2885 0 0 0 0 0 0 0 0 0 8.40659 9.98214 0 0 Q9UID3 VPS51_HUMAN Vacuolar protein sorting-associated protein 51 homolog (Another new gene 2 protein) (Protein fat-free homolog) VPS51 ANG2 C11orf2 C11orf3 FFR PP5382 Homo sapiens (Human) "autophagy [GO:0006914]; brain morphogenesis [GO:0048854]; endocytic recycling [GO:0032456]; Golgi organization [GO:0007030]; Golgi vesicle transport [GO:0048193]; lysosomal transport [GO:0007041]; protein targeting [GO:0006605]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle-mediated cholesterol transport [GO:0090119]" cytosol [GO:0005829]; EARP complex [GO:1990745]; GARP complex [GO:0000938]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleolus [GO:0005730]; recycling endosome [GO:0055037]; trans-Golgi network membrane [GO:0032588] 0.88952 -0.42128 AQSSDSSKR 0 8.98965 0 0 0 0 0 0 0 0 0 0 0 0 9.00068 0 0 0 0 0 0 0 0 0 9.72358 0 0 Q9UIE0 ZN230_HUMAN Zinc finger protein 230 (Zinc finger protein FDZF2) ZNF230 FDZF2 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.95441 -1.5308 LVHRSFCK 0 0 0 10.3895 0 0 11.0502 10.6293 0 11.4482 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UIF3 TEKT2_HUMAN Tektin-2 (Tektin-t) (Testicular tektin) (Testicular tektin B1-like protein) (TEKTB1) (Tektin-B1) TEKT2 Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement involved in cell motility [GO:0060294]; flagellated sperm motility [GO:0030317]; inner dynein arm assembly [GO:0036159] axonemal microtubule [GO:0005879]; microtubule cytoskeleton [GO:0015630]; microtubule organizing center [GO:0005815]; motile cilium [GO:0031514]; nucleus [GO:0005634] 0.96523 -2.3686 ATLSVKPSRR 0 0 0 0 0 0 10.0614 10.667 0 0 10.3723 0 0 9.41492 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UIF7 MUTYH_HUMAN Adenine DNA glycosylase (EC 3.2.2.31) (MutY homolog) (hMYH) MUTYH MYH Homo sapiens (Human) base-excision repair [GO:0006284]; depurination [GO:0045007]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]; negative regulation of necroptotic process [GO:0060546] mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; DNA N-glycosylase activity [GO:0019104]; metal ion binding [GO:0046872]; MutSalpha complex binding [GO:0032407]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]" 0.88668 -0.34035 AAVGSGHR 0 0 0 0 0 0 0 0 0 0 0 0 8.91094 0 0 0 0 0 0 0 0 0 0 0 0 0 9.40465 Q9UIF8 BAZ2B_HUMAN Bromodomain adjacent to zinc finger domain protein 2B (hWALp4) BAZ2B KIAA1476 Homo sapiens (Human) chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.96929 -3.5595 FYSPLPNDQLLK 0 0 12.0836 0 0 0 0 0 9.41743 0 0 0 0 0 0 0 9.87662 0 0 0 0 10.9347 0 0 0 0 10.4951 Q9UIF9 BAZ2A_HUMAN Bromodomain adjacent to zinc finger domain protein 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3) BAZ2A KIAA0314 TIP5 Homo sapiens (Human) chromatin remodeling [GO:0006338]; DNA methylation [GO:0006306]; DNA-templated transcription [GO:0006351]; heterochromatin formation [GO:0031507]; negative regulation of transcription by RNA polymerase I [GO:0016479]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of histone methylation [GO:0031062]; rDNA heterochromatin formation [GO:0000183]; regulation of DNA methylation [GO:0044030]; regulation of DNA-templated transcription [GO:0006355]; RNA polymerase I preinitiation complex assembly [GO:0001188] chromatin silencing complex [GO:0005677]; cytosol [GO:0005829]; NoRC complex [GO:0090536]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634]; rDNA heterochromatin [GO:0033553] DNA binding [GO:0003677]; histone binding [GO:0042393]; lysine-acetylated histone binding [GO:0070577]; metal ion binding [GO:0046872]; nuclear receptor binding [GO:0016922]; RNA binding [GO:0003723] 0.96951 -5.5243 AVSLGQDRYRR 0 0 0 0 0 0 0 0 0 0 0 9.81724 0 0 0 0 0 0 9.5328 0 10.6231 0 9.2747 0 0 0 0 Q9UIG0 BAZ1B_HUMAN Tyrosine-protein kinase BAZ1B (EC 2.7.10.2) (Bromodomain adjacent to zinc finger domain protein 1B) (Williams syndrome transcription factor) (Williams-Beuren syndrome chromosomal region 10 protein) (Williams-Beuren syndrome chromosomal region 9 protein) (hWALp2) BAZ1B WBSC10 WBSCR10 WBSCR9 WSTF Homo sapiens (Human) chromatin remodeling [GO:0006338]; DNA damage response [GO:0006974]; negative regulation of mitotic chromosome condensation [GO:1905213]; phosphorylation [GO:0016310]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; post-translational protein modification [GO:0043687]; regulation of transcription by RNA polymerase II [GO:0006357] B-WICH complex [GO:0110016]; condensed chromosome [GO:0000793]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; WICH complex [GO:0090535] ATP binding [GO:0005524]; histone binding [GO:0042393]; histone H2AXY142 kinase activity [GO:0140801]; histone kinase activity [GO:0035173]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein tyrosine kinase activity [GO:0004713]; zinc ion binding [GO:0008270] 0.96924 -6.0994 EEYEARLER 0 0 9.28778 0 0 0 9.86006 0 0 11.4731 0 0 0 0 0 0 0 0 0 0 0 0 0 8.91591 0 0 0 Q9UII4 HERC5_HUMAN E3 ISG15--protein ligase HERC5 (EC 2.3.2.-) (Cyclin-E-binding protein 1) (HECT domain and RCC1-like domain-containing protein 5) HERC5 CEB1 CEBP1 Homo sapiens (Human) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; ISG15-protein conjugation [GO:0032020]; protein ubiquitination [GO:0016567]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of defense response to virus [GO:0050688]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737]; cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471] ISG15 transferase activity [GO:0042296]; RNA binding [GO:0003723]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.92763 -1.1977 LESHTSEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.99078 0 0 0 Q9UII5 ZN107_HUMAN Zinc finger protein 107 (Zinc finger protein 588) (Zinc finger protein ZFD25) ZNF107 ZFD25 ZNF588 Homo sapiens (Human) nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.90231 -0.70184 AFNWFSTLTKHKR 0 10.3141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9347 0 0 0 0 9.76472 Q9UIJ5 ZDHC2_HUMAN Palmitoyltransferase ZDHHC2 (EC 2.3.1.225) (Acyltransferase ZDHHC2) (EC 2.3.1.-) (Reduced expression associated with metastasis protein) (Ream) (Reduced expression in cancer protein) (Rec) (Zinc finger DHHC domain-containing protein 2) (DHHC-2) (Zinc finger protein 372) ZDHHC2 REAM REC ZNF372 Homo sapiens (Human) peptidyl-L-cysteine S-palmitoylation [GO:0018230]; positive regulation of AMPA glutamate receptor clustering [GO:1904719]; positive regulation of endosome to plasma membrane protein transport [GO:1905751]; positive regulation of long-term synaptic potentiation [GO:1900273]; protein localization to membrane raft [GO:1903044]; protein localization to plasma membrane [GO:0072659]; protein localization to postsynaptic membrane [GO:1903539]; protein metabolic process [GO:0019538]; protein palmitoylation [GO:0018345]; protein targeting to membrane [GO:0006612]; regulation of cell-cell adhesion [GO:0022407]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of protein catabolic process [GO:0042176]; regulation of protein localization to plasma membrane [GO:1903076]; synapse assembly [GO:0007416] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic recycling endosome [GO:0098837]; recycling endosome membrane [GO:0055038] palmitoyltransferase activity [GO:0016409]; protein homodimerization activity [GO:0042803]; protein-cysteine S-myristoyltransferase activity [GO:0019705]; protein-cysteine S-palmitoyltransferase activity [GO:0019706]; protein-cysteine S-stearoyltransferase activity [GO:0140439] 0.93273 -1.2589 NMRQVFGDEKK 0 0 10.2651 0 0 0 11.041 0 11.1536 0 11.0711 10.8249 0 0 10.3565 0 10.9542 11.0013 0 0 0 0 0 0 0 0 0 Q9UIK4 DAPK2_HUMAN Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related protein 1) (DRP-1) DAPK2 Homo sapiens (Human) anoikis [GO:0043276]; apoptotic process [GO:0006915]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; positive regulation of eosinophil chemotaxis [GO:2000424]; positive regulation of neutrophil chemotaxis [GO:0090023]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of intrinsic apoptotic signaling pathway [GO:2001242] autophagosome lumen [GO:0034423]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634] ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.56557 0.50439 EKSTGLEYAAKFIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0188 Q9UIK5 TEFF2_HUMAN Tomoregulin-2 (TR-2) (Hyperplastic polyposis protein 1) (Transmembrane protein with EGF-like and two follistatin-like domains) TMEFF2 HPP1 TENB2 TPEF UNQ178/PRO204 Homo sapiens (Human) "cell differentiation [GO:0030154]; negative regulation of cell migration [GO:0030336]; negative regulation of integrin biosynthetic process [GO:0045720]; negative regulation of stress fiber assembly [GO:0051497]; wound healing, spreading of cells [GO:0044319]" extracellular region [GO:0005576]; membrane [GO:0016020] 0.93178 -1.2527 EASCQKQEK 0 0 0 0 0 0 0 0 0 0 0 10.4928 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UIL8 PHF11_HUMAN PHD finger protein 11 (BRCA1 C-terminus-associated protein) (Renal carcinoma antigen NY-REN-34) PHF11 BCAP Homo sapiens (Human) nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] metal ion binding [GO:0046872] 0.91491 -0.79606 RTCALCPK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.4671 0 9.90603 0 0 0 0 0 0 0 0 0 0 0 Q9UIM3 FKBPL_HUMAN FK506-binding protein-like (WAF-1/CIP1 stabilizing protein 39) (WISp39) FKBPL DIR1 NG7 Homo sapiens (Human) regulation of blood vessel branching [GO:1905553]; response to radiation [GO:0009314] cytosol [GO:0005829]; extracellular region [GO:0005576] 0.9566 -1.542 EALAREER 0 0 0 0 0 0 0 0 0 0 10.4628 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UIS9 MBD1_HUMAN Methyl-CpG-binding domain protein 1 (CXXC-type zinc finger protein 3) (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1) MBD1 CXXC3 PCM1 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; transcription by RNA polymerase II [GO:0006366] chromosome [GO:0005694]; intracellular membrane-bounded organelle [GO:0043231]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; double-stranded methylated DNA binding [GO:0010385]; methyl-CpG binding [GO:0008327]; unmethylated CpG binding [GO:0045322]; zinc ion binding [GO:0008270] 0.39446 0.70825 CGACAACLRR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.0847 8.98948 0 0 0 0 0 0 0 0 0 0 0 0 Q9UIU6 SIX4_HUMAN Homeobox protein SIX4 (Sine oculis homeobox homolog 4) SIX4 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; embryonic cranial skeleton morphogenesis [GO:0048701]; fungiform papilla morphogenesis [GO:0061197]; generation of neurons [GO:0048699]; inner ear morphogenesis [GO:0042472]; male gonad development [GO:0008584]; male sex determination [GO:0030238]; male sex differentiation [GO:0046661]; metanephric mesenchyme development [GO:0072075]; myoblast migration [GO:0051451]; myotome development [GO:0061055]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of satellite cell differentiation [GO:1902725]; olfactory placode formation [GO:0030910]; pharyngeal system development [GO:0060037]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of ureteric bud formation [GO:0072107]; protein localization to nucleus [GO:0034504]; regulation of branch elongation involved in ureteric bud branching [GO:0072095]; regulation of epithelial cell proliferation [GO:0050678]; regulation of protein localization [GO:0032880]; regulation of synaptic assembly at neuromuscular junction [GO:0008582]; regulation of transcription by RNA polymerase II [GO:0006357]; sarcomere organization [GO:0045214]; skeletal muscle fiber differentiation [GO:0098528]; skeletal muscle tissue development [GO:0007519]; thymus development [GO:0048538]; tongue development [GO:0043586]; trigeminal ganglion development [GO:0061551] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.93031 -1.247 EKSRNALK 0 0 0 0 0 0 0 0 0 9.31125 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UIV8 SPB13_HUMAN Serpin B13 (HaCaT UV-repressible serpin) (Hurpin) (Headpin) (Peptidase inhibitor 13) (PI-13) (Proteinase inhibitor 13) SERPINB13 PI13 Homo sapiens (Human) negative regulation of endopeptidase activity [GO:0010951]; negative regulation of keratinocyte apoptotic process [GO:1902173]; regulation of proteolysis [GO:0030162]; response to UV [GO:0009411] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654] cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]; serine-type endopeptidase inhibitor activity [GO:0004867] 0.95066 -1.4083 ENTKEEKFWMNK 0 0 0 0 0 0 0 0 0 0 8.85325 0 9.91686 0 0 0 10.2143 9.57845 0 0 0 0 0 0 0 0 0 Q9UJ04 TSYL4_HUMAN Testis-specific Y-encoded-like protein 4 (TSPY-like protein 4) TSPYL4 KIAA0721 Homo sapiens (Human) nucleosome assembly [GO:0006334] chromatin [GO:0000785]; nucleus [GO:0005634] chromatin binding [GO:0003682]; histone binding [GO:0042393] 0.88134 -0.30756 EYERRSSGR 0 0 0 0 0 0 0 0 0 0 12.1546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UJ14 GGT7_HUMAN Glutathione hydrolase 7 (EC 3.4.19.13) (Gamma-glutamyltransferase 7) (GGT 7) (EC 2.3.2.2) (Gamma-glutamyltransferase-like 3) (Gamma-glutamyltransferase-like 5) (Gamma-glutamyltranspeptidase 7) [Cleaved into: Glutathione hydrolase 7 heavy chain; Glutathione hydrolase 7 light chain] GGT7 GGTL3 GGTL5 Homo sapiens (Human) glutathione biosynthetic process [GO:0006750]; glutathione catabolic process [GO:0006751]; leukotriene D4 biosynthetic process [GO:1901750]; negative regulation of response to oxidative stress [GO:1902883] plasma membrane [GO:0005886] glutathione hydrolase activity [GO:0036374]; hypoglycin A gamma-glutamyl transpeptidase activity [GO:0102953]; leukotriene C4 gamma-glutamyl transferase activity [GO:0103068] 0.85014 0.11729 DPFSAAAAECSCR 0 0 0 0 0 0 0 0 0 12.1388 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UJ41 RABX5_HUMAN Rab5 GDP/GTP exchange factor (RAP1) (Rabaptin-5-associated exchange factor for Rab5) (Rabex-5) RABGEF1 RABEX5 Homo sapiens (Human) dendritic transport [GO:0098935]; Kit signaling pathway [GO:0038109]; mast cell degranulation [GO:0043303]; mast cell migration [GO:0097531]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of Kit signaling pathway [GO:1900235]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of receptor-mediated endocytosis [GO:0048261]; protein phosphorylation [GO:0006468]; protein targeting to membrane [GO:0006612]; Ras protein signal transduction [GO:0007265]; receptor-mediated endocytosis [GO:0006898]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368] cytosol [GO:0005829]; dendrite [GO:0030425]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; nucleolus [GO:0005730]; recycling endosome [GO:0055037] DNA binding [GO:0003677]; guanyl-nucleotide exchange factor activity [GO:0005085]; small GTPase binding [GO:0031267]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.91609 -0.83931 EVQDIVEK 10.3606 10.5018 10.4185 0 0 0 0 0 0 0 10.0901 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UJ68 MSRA_HUMAN Mitochondrial peptide methionine sulfoxide reductase (EC 1.8.4.11) (Peptide-methionine (S)-S-oxide reductase) (Peptide Met(O) reductase) (Protein-methionine-S-oxide reductase) (PMSR) MSRA Homo sapiens (Human) cellular response to oxidative stress [GO:0034599]; methionine metabolic process [GO:0006555]; protein modification process [GO:0036211]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] L-methionine-(S)-S-oxide reductase activity [GO:0036456]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113] 0.59217 0.45636 ACQLLLLHSLFPVPR 0 0 0 0 0 0 0 0 0 9.45625 0 0 0 0 0 0 0 0 0 0 0 9.84604 0 0 0 0 0 Q9UJ70 NAGK_HUMAN N-acetyl-D-glucosamine kinase (N-acetylglucosamine kinase) (EC 2.7.1.59) (GlcNAc kinase) (Muramyl dipeptide kinase) (EC 2.7.1.-) (N-acetyl-D-mannosamine kinase) (EC 2.7.1.60) NAGK Homo sapiens (Human) N-acetylglucosamine metabolic process [GO:0006044]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262] cytosol [GO:0005829]; extracellular exosome [GO:0070062] ATP binding [GO:0005524]; N-acetylglucosamine kinase activity [GO:0045127] 0.020548 1.6169 AAIYGGVEGGGTR 11.4729 0 10.9963 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5976 0 0 0 0 10.0932 9.5561 0 0 0 0 Q9UJ72 ANX10_HUMAN Annexin A10 (Annexin-10) (Annexin-14) ANXA10 ANX14 Homo sapiens (Human) cytoplasm [GO:0005737] calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544] 0.96316 -2.0897 TVIRILIAR 0 0 0 10.106 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UJ78 ZMYM5_HUMAN Zinc finger MYM-type protein 5 (Zinc finger protein 198-like 1) (Zinc finger protein 237) ZMYM5 ZNF198L1 ZNF237 HSPC050 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] zinc ion binding [GO:0008270] 0.95482 -1.6246 KIEGIPEK 0 9.77545 0 0 0 0 0 0 0 0 0 0 0 0 9.22284 0 0 0 0 0 0 0 0 0 0 0 0 Q9UJ83 HACL1_HUMAN 2-hydroxyacyl-CoA lyase 1 (EC 4.1.2.63) (2-hydroxyphytanoyl-CoA lyase) (2-HPCL) (Phytanoyl-CoA 2-hydroxylase 2) HACL1 HPCL HPCL2 PHYH2 HSPC279 Homo sapiens (Human) fatty acid alpha-oxidation [GO:0001561]; fatty acid metabolic process [GO:0006631]; methyl-branched fatty acid metabolic process [GO:0097089]; phytanic acid metabolic process [GO:1903512]; protein targeting to peroxisome [GO:0006625] cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777] 2-hydroxy-3-methylhexadecanoyl-CoA lyase activity [GO:0106360]; 2-hydroxyphytanoyl-CoA lyase activity [GO:0106376]; ATP binding [GO:0005524]; carbon-carbon lyase activity [GO:0016830]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976] 0.91541 -0.7941 ALQFADVIVLFGAR 0 0 0 0 9.96665 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UJ98 STAG3_HUMAN Cohesin subunit SA-3 (SCC3 homolog 3) (Stromal antigen 3) (Stromalin-3) STAG3 Homo sapiens (Human) establishment of meiotic sister chromatid cohesion [GO:0034089]; sister chromatid cohesion [GO:0007062]; synaptonemal complex assembly [GO:0007130] "chromatin [GO:0000785]; chromosome, centromeric region [GO:0000775]; cohesin complex [GO:0008278]; extracellular space [GO:0005615]; meiotic cohesin complex [GO:0030893]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; synaptonemal complex [GO:0000795]" chromatin binding [GO:0003682] 0.92718 -1.191 GIVTPEMFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5037 0 0 0 0 0 0 8.98667 Q9UJ99 CAD22_HUMAN Cadherin-22 (Pituitary and brain cadherin) (PB-cadherin) CDH22 C20orf25 Homo sapiens (Human) adherens junction organization [GO:0034332]; brain development [GO:0007420]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] adherens junction [GO:0005912]; catenin complex [GO:0016342] cadherin binding [GO:0045296]; calcium ion binding [GO:0005509] 0.23011 0.85602 LLEPESEFIIK 0 14.2742 0 0 0 0 0 0 11.8773 0 0 0 0 12.1363 0 0 0 13.4066 0 0 0 0 0 0 0 0 0 Q9UJA2 CRLS1_HUMAN Cardiolipin synthase (CMP-forming) (CLS) (EC 2.7.8.41) (Protein GCD10 homolog) CRLS1 C20orf155 CLS1 Homo sapiens (Human) cardiolipin biosynthetic process [GO:0032049]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; response to phosphatidylethanolamine [GO:1905711]; response to thyroxine [GO:0097068] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] 1-acylglycerol-3-phosphate O-acyltransferase activity [GO:0003841]; 2-acylglycerol-3-phosphate O-acyltransferase activity [GO:0047144]; cardiolipin synthase (CMP-forming) [GO:0043337]; cardiolipin synthase activity [GO:0008808] 0.96342 -2.1002 LPGIGQRNHCSGAGK 0 0 0 0 8.87738 9.11473 10.6636 0 0 10.1648 0 10.2883 10.7347 9.39215 0 9.83208 0 0 0 0 0 0 0 0 9.65519 0 0 Q9UJA3 MCM8_HUMAN DNA helicase MCM8 (EC 3.6.4.12) (Minichromosome maintenance 8) MCM8 C20orf154 Homo sapiens (Human) cell cycle [GO:0007049]; DNA damage response [GO:0006974]; DNA duplex unwinding [GO:0032508]; double-strand break repair via homologous recombination [GO:0000724]; female gamete generation [GO:0007292]; male gamete generation [GO:0048232]; mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication [GO:0070716]; protein localization to chromatin [GO:0071168]; protein stabilization [GO:0050821]; recombinational interstrand cross-link repair [GO:0036298] chromosome [GO:0005694]; MCM complex [GO:0042555]; MCM8-MCM9 complex [GO:0097362]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; helicase activity [GO:0004386]; MutLbeta complex binding [GO:0032406]; MutSalpha complex binding [GO:0032407]; MutSbeta complex binding [GO:0032408]; single-stranded DNA binding [GO:0003697] 0.96787 -2.9449 DLYAIQEIQAEENLFK 0 10.5209 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5537 0 11.6206 Q9UJA5 TRM6_HUMAN tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 (mRNA methyladenosine-N(1)-methyltransferase non-catalytic subunit TRM6) (tRNA(m1A58)-methyltransferase subunit TRM6) (tRNA(m1A58)MTase subunit TRM6) TRMT6 KIAA1153 TRM6 CGI-09 Homo sapiens (Human) mRNA methylation [GO:0080009]; tRNA methylation [GO:0030488] nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tRNA (m1A) methyltransferase complex [GO:0031515] RNA binding [GO:0003723] 0.94062 -1.3171 EDVFKAVQVQR 0 0 0 0 0 0 0 0 0 0 0 8.43921 0 0 0 0 0 10.2055 0 8.58222 11.0144 0 9.3966 0 10.8999 0 0 Q9UJA9 ENPP5_HUMAN Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (E-NPP 5) (NPP-5) (EC 3.1.-.-) ENPP5 UNQ550/PRO1107 Homo sapiens (Human) cell communication [GO:0007154] extracellular region [GO:0005576]; plasma membrane [GO:0005886] NAD+ diphosphatase activity [GO:0000210]; zinc ion binding [GO:0008270] 0.86991 0.04592 SFSLDHMNIYDSK 0 0 0 0 0 0 8.37356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UJC5 SH3L2_HUMAN SH3 domain-binding glutamic acid-rich-like protein 2 (Fovea-associated SH3 domain-binding protein) SH3BGRL2 FASH3 Homo sapiens (Human) cytoplasm [GO:0005737]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654] SH3 domain binding [GO:0017124] 0.94019 -1.3067 LASKAEP 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.79409 0 0 0 0 Q9UJF2 NGAP_HUMAN Ras GTPase-activating protein nGAP (RAS protein activator-like 2) RASAL2 NGAP Homo sapiens (Human) adipose tissue development [GO:0060612]; gene expression [GO:0010467]; multicellular organism growth [GO:0035264]; regulation of GTPase activity [GO:0043087]; regulation of protein activation cascade [GO:2000257]; response to dietary excess [GO:0002021]; response to glucose [GO:0009749]; signal transduction [GO:0007165] cytosol [GO:0005829] GTPase activator activity [GO:0005096] 0.9231 -1.1559 IVSLDSANTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.48121 0 0 0 0 0 8.35429 Q9UJG1 MSPD1_HUMAN Motile sperm domain-containing protein 1 MOSPD1 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944] cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] 0.80815 0.22875 LQVSEQSQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3136 0 0 Q9UJH8 METRN_HUMAN Meteorin METRN C16orf23 RJD6 Homo sapiens (Human) axonogenesis [GO:0007409]; glial cell differentiation [GO:0010001]; positive regulation of axonogenesis [GO:0050772]; radial glial cell differentiation [GO:0060019] extracellular space [GO:0005615] hormone activity [GO:0005179] 0.88383 -0.12635 FGEARLGCAPRFQEFR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0874 0 0 0 0 0 0 0 0 0 0 0 0 Q9UJJ9 GNPTG_HUMAN N-acetylglucosamine-1-phosphotransferase subunit gamma (GlcNAc-1-phosphotransferase subunit gamma) (UDP-N-acetylglucosamine-1-phosphotransferase subunit gamma) GNPTG C16orf27 GNPTAG CAB56184 LP2537 Homo sapiens (Human) carbohydrate phosphorylation [GO:0046835]; N-glycan processing to lysosome [GO:0016256] extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complex [GO:0070622] protein homodimerization activity [GO:0042803]; UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity [GO:0003976] 0.64613 0.39623 MAAGLAR 0 0 0 0 0 0 0 0 0 0 0 0 0 11.6861 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UJL9 ZF69B_HUMAN Zinc finger protein 69 homolog B (Zinc finger protein 643) ZFP69B ZNF643 Homo sapiens (Human) Golgi organization [GO:0007030]; negative regulation of transcription by RNA polymerase II [GO:0000122] nucleolus [GO:0005730]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.9618 -2.6063 LESQQENQRMGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.76183 0 0 0 0 Q9UJM3 ERRFI_HUMAN ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein) (MIG-6) ERRFI1 MIG6 Homo sapiens (Human) cellular hyperosmotic response [GO:0071474]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to insulin stimulus [GO:0032869]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; lung alveolus development [GO:0048286]; lung epithelium development [GO:0060428]; lung vasculature development [GO:0060426]; negative regulation of cardiac muscle hypertrophy in response to stress [GO:1903243]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of keratinocyte differentiation [GO:0045616]; regulation of type B pancreatic cell proliferation [GO:0061469]; skin morphogenesis [GO:0043589] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nucleus [GO:0005634]; plasma membrane [GO:0005886] GTPase activator activity [GO:0005096]; protein kinase binding [GO:0019901]; SH3 domain binding [GO:0017124]; small GTPase binding [GO:0031267] 0.27448 0.83872 AMGNMRK 9.72511 0 9.49747 0 0 0 9.53415 0 0 9.36835 9.56045 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UJM8 HAOX1_HUMAN 2-Hydroxyacid oxidase 1 (HAOX1) (EC 1.1.3.15) (Glycolate oxidase) (GO) (GOX) (Glyoxylate oxidase) (EC 1.2.3.5) HAO1 GOX1 Homo sapiens (Human) fatty acid alpha-oxidation [GO:0001561]; glycine biosynthetic process [GO:0006545]; glycolate catabolic process [GO:0046296]; response to oxidative stress [GO:0006979] cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; peroxisomal matrix [GO:0005782] (S)-2-hydroxy-acid oxidase activity [GO:0003973]; FMN binding [GO:0010181]; glyoxylate oxidase activity [GO:0047969] 0.89636 -0.54372 MGYKAIFVTVDTPYLGNR 0 9.78789 8.84216 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UJN7 ZN391_HUMAN Zinc finger protein 391 ZNF391 Homo sapiens (Human) nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.96304 -2.6559 GFSRSSSLIIHQRTHTGEKPYK 0 0 0 12.1307 0 0 0 0 0 11.2279 11.3029 9.18304 0 0 0 0 11.8275 0 0 0 0 0 0 0 0 0 0 Q9UJQ1 LAMP5_HUMAN Lysosome-associated membrane glycoprotein 5 (Brain and dendritic cell-associated LAMP) (Brain-associated LAMP-like protein) (BAD-LAMP) (Lysosome-associated membrane protein 5) (LAMP-5) LAMP5 C20orf103 Homo sapiens (Human) cytoplasmic vesicle membrane [GO:0030659]; dendrite membrane [GO:0032590]; early endosome membrane [GO:0031901]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endosome membrane [GO:0010008]; growth cone membrane [GO:0032584]; late endosome [GO:0005770]; lysosome [GO:0005764]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; synaptic vesicle membrane [GO:0030672] 0.76152 0.2902 VQFVYDSSEK 0 0 0 0 0 10.1577 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UJQ4 SALL4_HUMAN Sal-like protein 4 (Zinc finger protein 797) (Zinc finger protein SALL4) SALL4 ZNF797 Homo sapiens (Human) embryonic limb morphogenesis [GO:0030326]; inner cell mass cell proliferation [GO:0001833]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; somatic stem cell population maintenance [GO:0035019]; ventricular septum development [GO:0003281] cytoplasm [GO:0005737]; heterochromatin [GO:0000792]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96955 -3.4993 GNLKVHFHRHPQVK 0 12.572 0 0 0 0 0 0 0 14.0295 0 13.9762 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UJS0 S2513_HUMAN "Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (Calcium-binding mitochondrial carrier protein Aralar2) (ARALAR-related gene 2) (ARALAR2) (Citrin) (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13)" SLC25A13 Homo sapiens (Human) aspartate family amino acid metabolic process [GO:0009066]; aspartate transmembrane transport [GO:0015810]; ATP biosynthetic process [GO:0006754]; cellular respiration [GO:0045333]; gluconeogenesis [GO:0006094]; L-glutamate transmembrane transport [GO:0015813]; malate-aspartate shuttle [GO:0043490]; mitochondrial transport [GO:0006839]; response to calcium ion [GO:0051592] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886] "3-sulfino-L-alanine: proton, glutamate antiporter activity [GO:0000514]; acidic amino acid transmembrane transporter activity [GO:0015172]; aspartate:glutamate, proton antiporter activity [GO:0000515]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; L-aspartate transmembrane transporter activity [GO:0015183]; L-glutamate transmembrane transporter activity [GO:0005313]" 0.13787 1.0463 IAPLEEGTLPFNLAEAQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.33215 9.13794 0 0 0 0 10.3206 10.2977 0 Q9UJT1 TBD_HUMAN Tubulin delta chain (Delta-tubulin) TUBD1 TUBD Homo sapiens (Human) cell projection organization [GO:0030030]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; positive regulation of smoothened signaling pathway [GO:0045880] centriole [GO:0005814]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; microtubule [GO:0005874]; nucleoplasm [GO:0005654] GTP binding [GO:0005525]; structural constituent of cytoskeleton [GO:0005200] 0.80753 0.23023 VINQMLSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.61596 0 0 0 0 0 0 0 0 0 Q9UJU3 ZN112_HUMAN Zinc finger protein 112 (Zfp-112) (Zinc finger protein 228) ZNF112 ZFP112 ZNF228 Homo sapiens (Human) nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96732 -2.3298 CEMCGKGFSQSSR 0 0 9.78293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.61532 0 0 Q9UJU6 DBNL_HUMAN Drebrin-like protein (Cervical SH3P7) (Cervical mucin-associated protein) (Drebrin-F) (HPK1-interacting protein of 55 kDa) (HIP-55) (SH3 domain-containing protein 7) DBNL CMAP SH3P7 PP5423 Homo sapiens (Human) adaptive immune response [GO:0002250]; endocytosis [GO:0006897]; membrane organization [GO:0061024]; neuron projection morphogenesis [GO:0048812]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; synapse assembly [GO:0007416] anchoring junction [GO:0070161]; cell cortex [GO:0005938]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; early endosome [GO:0005769]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; membrane [GO:0016020]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724] actin binding [GO:0003779]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; enzyme activator activity [GO:0008047]; protein domain specific binding [GO:0019904]; structural constituent of postsynaptic actin cytoskeleton [GO:0098973] 0.9246 -1.0076 DPNSGLPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.55771 0 0 0 0 0 Q9UJV3 TRIM1_HUMAN Probable E3 ubiquitin-protein ligase MID2 (EC 2.3.2.27) (Midin-2) (Midline defect 2) (Midline-2) (RING finger protein 60) (RING-type E3 ubiquitin transferase MID2) (Tripartite motif-containing protein 1) MID2 FXY2 RNF60 TRIM1 Homo sapiens (Human) innate immune response [GO:0045087]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral transcription [GO:0032897]; positive regulation of autophagy [GO:0010508]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein localization to microtubule [GO:0035372]; protein ubiquitination [GO:0016567]; suppression of viral release by host [GO:0044790] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; microtubule [GO:0005874] enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; phosphoprotein binding [GO:0051219]; protein homodimerization activity [GO:0042803]; transcription coactivator activity [GO:0003713]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270] 0.8841 -0.13199 AINQAGSR 0 0 0 0 0 0 0 0 0 0 0 0 9.09077 9.2593 0 0 0 0 0 0 9.34012 0 0 10.0804 0 0 0 Q9UJV9 DDX41_HUMAN Probable ATP-dependent RNA helicase DDX41 (EC 3.6.4.13) (DEAD box protein 41) (DEAD box protein abstrakt homolog) DDX41 ABS Homo sapiens (Human) "apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; mRNA splicing, via spliceosome [GO:0000398]" catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.96968 -4.6705 LEAMQTK 0 0 0 0 0 0 0 0 0 0 0 9.36102 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UJW0 DCTN4_HUMAN Dynactin subunit 4 (Dyn4) (Dynactin subunit p62) DCTN4 Homo sapiens (Human) cell cortex [GO:0005938]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; cytosol [GO:0005829]; dynactin complex [GO:0005869]; focal adhesion [GO:0005925]; kinetochore [GO:0000776]; nucleus [GO:0005634]; sarcomere [GO:0030017]; spindle pole [GO:0000922]; stress fiber [GO:0001725] 0.55973 0.52485 DVGMADK 10.7765 10.7996 0 0 0 0 0 0 0 0 0 0 0 0 0 8.87495 8.75999 0 0 0 0 0 0 0 0 9.70596 0 Q9UJW2 TINAG_HUMAN Tubulointerstitial nephritis antigen (TIN-Ag) TINAG Homo sapiens (Human) cell adhesion [GO:0007155]; proteolysis [GO:0006508] basement membrane [GO:0005604]; extracellular space [GO:0005615] cysteine-type endopeptidase activity [GO:0004197]; nucleotide binding [GO:0000166] 0.95982 -1.9294 AWWYLRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7.83731 0 8.61739 0 0 0 10.3757 Q9UJW8 ZN180_HUMAN Zinc finger protein 180 (HHZ168) ZNF180 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.88494 -0.18611 DVILENHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.687 0 0 0 0 10.5097 0 0 0 Q9UJX0 OSGI1_HUMAN "Oxidative stress-induced growth inhibitor 1 (Bone marrow stromal cell-derived growth inhibitor) (BMSC-derived growth inhibitor) (Ovary, kidney and liver protein 38) (huOKL38) (Pregnancy-induced growth inhibitor OKL38)" OSGIN1 BDGI OKL38 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of cell growth [GO:0030308]; regulation of apoptotic process [GO:0042981]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127] growth factor activity [GO:0008083] 0.8808 -0.30811 SLPRHQLLCFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.91537 0 0 0 0 0 0 0 0 0 Q9UJX2 CDC23_HUMAN Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8) CDC23 ANAPC8 Homo sapiens (Human) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; mitotic cell cycle [GO:0000278]; mitotic metaphase plate congression [GO:0007080]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; protein K11-linked ubiquitination [GO:0070979]; regulation of exit from mitosis [GO:0007096]; regulation of meiotic cell cycle [GO:0051445]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; ubiquitin-dependent protein catabolic process [GO:0006511] anaphase-promoting complex [GO:0005680]; cytosol [GO:0005829]; nucleoplasm [GO:0005654] ubiquitin-protein transferase activity [GO:0004842] 0.88837 -0.43509 AYAVGDVEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.5952 9.26578 0 Q9UJX3 APC7_HUMAN Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7) ANAPC7 APC7 Homo sapiens (Human) anaphase-promoting complex-dependent catabolic process [GO:0031145]; brain development [GO:0007420]; cell cycle [GO:0007049]; cell division [GO:0051301]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; protein K11-linked ubiquitination [GO:0070979]; protein ubiquitination [GO:0016567]; regulation of meiotic cell cycle [GO:0051445]; regulation of mitotic cell cycle [GO:0007346] anaphase-promoting complex [GO:0005680]; cytosol [GO:0005829]; heterochromatin [GO:0000792]; microtubule cytoskeleton [GO:0015630]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819] enzyme-substrate adaptor activity [GO:0140767]; protein phosphatase binding [GO:0019903] 0.92403 -1.1734 AGDNKNSVLK 0 0 0 0 0 0 0 0 11.0612 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6668 0 0 Q9UJX4 APC5_HUMAN Anaphase-promoting complex subunit 5 (APC5) (Cyclosome subunit 5) ANAPC5 APC5 Homo sapiens (Human) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell cycle [GO:0007049]; cell division [GO:0051301]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; protein K11-linked ubiquitination [GO:0070979]; regulation of meiotic cell cycle [GO:0051445]; regulation of mitotic cell cycle [GO:0007346] anaphase-promoting complex [GO:0005680]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819] protein phosphatase binding [GO:0019903] 0.92297 -1.1459 DSDLLHWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.10625 0 0 0 0 0 0 0 9.41606 0 0 0 Q9UJX6 ANC2_HUMAN Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2) ANAPC2 APC2 KIAA1406 Homo sapiens (Human) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell differentiation [GO:0030154]; cell division [GO:0051301]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; negative regulation of gene expression [GO:0010629]; nervous system development [GO:0007399]; positive regulation of axon extension [GO:0045773]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic plasticity [GO:0031915]; protein K11-linked ubiquitination [GO:0070979]; regulation of meiotic cell cycle [GO:0051445]; regulation of mitotic cell cycle [GO:0007346] anaphase-promoting complex [GO:0005680]; cytosol [GO:0005829]; nucleoplasm [GO:0005654] ubiquitin protein ligase binding [GO:0031625] 0.9678 -3.6728 AALEAYCKK 0 0 0 0 9.45703 0 0 0 0 0 0 0 8.90078 0 0 0 0 0 0 0 0 0 9.69943 0 0 10.4379 0 Q9UJY4 GGA2_HUMAN "ADP-ribosylation factor-binding protein GGA2 (Gamma-adaptin-related protein 2) (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear)" GGA2 KIAA1080 Homo sapiens (Human) Golgi to plasma membrane protein transport [GO:0043001]; Golgi to plasma membrane transport [GO:0006893]; intracellular protein transport [GO:0006886]; protein localization to cell surface [GO:0034394] clathrin-coated vesicle [GO:0030136]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; trans-Golgi network [GO:0005802] phosphatidylinositol binding [GO:0035091]; small GTPase binding [GO:0031267]; ubiquitin binding [GO:0043130] 0.86022 0.098981 LLKSNHPEDLQAANR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8207 0 0 0 0 0 0 0 0 0 0 10.5263 0 Q9UJZ1 STML2_HUMAN "Stomatin-like protein 2, mitochondrial (SLP-2) (EPB72-like protein 2) (Paraprotein target 7) (Paratarg-7)" STOML2 SLP2 HSPC108 Homo sapiens (Human) "CD4-positive, alpha-beta T cell activation [GO:0035710]; intracellular calcium ion homeostasis [GO:0006874]; lipid localization [GO:0010876]; mitochondrial protein processing [GO:0034982]; mitochondrion organization [GO:0007005]; positive regulation of interleukin-2 production [GO:0032743]; protein complex oligomerization [GO:0051259]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]; stress-induced mitochondrial fusion [GO:1990046]; T cell receptor signaling pathway [GO:0050852]" actin cytoskeleton [GO:0015629]; immunological synapse [GO:0001772]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886] cardiolipin binding [GO:1901612]; GTPase binding [GO:0051020]; T cell receptor binding [GO:0042608] 0.27785 0.83717 APVPGTPDSLSSGSSR 0 0 0 0 0 0 0 0 0 0 9.19609 0 0 0 0 0 0 0 0 0 0 0 8.49354 0 0 0 0 Q9UK05 GDF2_HUMAN Growth/differentiation factor 2 (GDF-2) (Bone morphogenetic protein 9) (BMP-9) GDF2 BMP9 Homo sapiens (Human) activin receptor signaling pathway [GO:0032924]; angiogenesis [GO:0001525]; blood vessel morphogenesis [GO:0048514]; BMP signaling pathway [GO:0030509]; branching involved in blood vessel morphogenesis [GO:0001569]; cartilage development [GO:0051216]; cellular response to BMP stimulus [GO:0071773]; intracellular iron ion homeostasis [GO:0006879]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell growth [GO:0030308]; negative regulation of DNA biosynthetic process [GO:2000279]; negative regulation of DNA replication [GO:0008156]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; positive regulation of angiogenesis [GO:0045766]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cartilage development [GO:0061036]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transcription by RNA polymerase II [GO:0045944]; SMAD protein signal transduction [GO:0060395]; transcription by RNA polymerase II [GO:0006366]; vasculogenesis [GO:0001570] cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615] BMP receptor binding [GO:0070700]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; protein serine/threonine kinase activator activity [GO:0043539]; signaling receptor activator activity [GO:0030546] 0.41876 0.6746 SFSMEDAISITATEDFPFQK 0 9.48551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1996 Q9UK08 GBG8_HUMAN Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 (Gamma-9) GNG8 GNG9 GNGT9 Homo sapiens (Human) cellular response to pheromone [GO:0071444]; G protein-coupled receptor signaling pathway [GO:0007186]; nose development [GO:0043584]; social behavior [GO:0035176] heterotrimeric G-protein complex [GO:0005834]; plasma membrane [GO:0005886] G-protein beta-subunit binding [GO:0031681]; GTPase activity [GO:0003924] 0.95429 -1.5055 LEVNIDRMK 0 0 0 0 0 0 0 0 0 9.2173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UK11 ZN223_HUMAN Zinc finger protein 223 ZNF223 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.96365 -2.1067 CEQCGRGFRCR 0 0 0 10.3748 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8969 0 0 Q9UK12 ZN222_HUMAN Zinc finger protein 222 ZNF222 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.96938 -4.5929 LVCRSYCK 0 0 0 0 0 0 0 0 0 10.2902 0 0 0 0 0 0 10.0501 0 0 9.14748 0 8.80352 0 0 0 0 0 Q9UK13 ZN221_HUMAN Zinc finger protein 221 ZNF221 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.95286 -1.4806 GFICRRDFCK 10.7701 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.39369 0 0 0 0 0 0 0 0 0 Q9UK23 NAGPA_HUMAN N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (EC 3.1.4.45) (Mannose 6-phosphate-uncovering enzyme) (Phosphodiester alpha-GlcNAcase) NAGPA Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; lysosome organization [GO:0007040]; protein glycosylation [GO:0006486]; protein modification process [GO:0036211]; protein targeting to lysosome [GO:0006622]; secretion of lysosomal enzymes [GO:0033299] Golgi cisterna membrane [GO:0032580]; membrane [GO:0016020] N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity [GO:0003944] 0.95377 -1.514 AVAGHLTRAVEPLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.23117 0 10.2458 Q9UK32 KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (p90RSK6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) RPS6KA6 RSK4 Homo sapiens (Human) "central nervous system development [GO:0007417]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; negative regulation of embryonic development [GO:0045992]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mesoderm development [GO:2000381]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; ribosomal protein S6 kinase activity [GO:0004711] 0.63147 0.40075 EVLFTEEDVK 0 0 10.684 0 0 0 0 0 0 0 0 0 10.0787 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UK39 NOCT_HUMAN Nocturnin (EC 3.1.3.108) (Carbon catabolite repression 4-like protein) NOCT CCR4 CCRN4L NOC Homo sapiens (Human) circadian regulation of gene expression [GO:0032922]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; mRNA stabilization [GO:0048255]; NADP metabolic process [GO:0006739]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoblast differentiation [GO:0045668]; P-body assembly [GO:0033962]; positive regulation of fat cell differentiation [GO:0045600]; regulation of circadian rhythm [GO:0042752]; regulation of embryonic development [GO:0045995]; response to extracellular stimulus [GO:0009991]; response to lipopolysaccharide [GO:0032496]; transcription by RNA polymerase II [GO:0006366] cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; perinuclear region of cytoplasm [GO:0048471] 3'-5'-RNA exonuclease activity [GO:0000175]; metal ion binding [GO:0046872]; mRNA binding [GO:0003729]; NADP phosphatase activity [GO:0019178]; NADPH phosphatase activity [GO:0102757]; poly(A)-specific ribonuclease activity [GO:0004535] 0.91575 -0.77642 HTLDYIWYSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.81678 Q9UK41 VPS28_HUMAN Vacuolar protein sorting-associated protein 28 homolog (H-Vps28) (ESCRT-I complex subunit VPS28) VPS28 Homo sapiens (Human) macroautophagy [GO:0016236]; membrane fission [GO:0090148]; multivesicular body assembly [GO:0036258]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of ubiquitin-dependent endocytosis [GO:2000397]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding via host ESCRT complex [GO:0039702] cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; endosome membrane [GO:0010008]; ESCRT I complex [GO:0000813]; extracellular exosome [GO:0070062]; late endosome membrane [GO:0031902]; plasma membrane [GO:0005886] protein-containing complex binding [GO:0044877]; ubiquitin binding [GO:0043130] 0.94827 -1.3687 LDCPLAMERIK 0 0 0 0 10.4157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UK53 ING1_HUMAN Inhibitor of growth protein 1 ING1 Homo sapiens (Human) cell cycle [GO:0007049]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of stem cell population maintenance [GO:1902459]; protein import into nucleus [GO:0006606]; regulation of programmed cell death [GO:0043067] nucleus [GO:0005634]; Sin3 complex [GO:0016580] metal ion binding [GO:0046872]; methylated histone binding [GO:0035064] 0.95626 -1.5417 TMDKALEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1619 0 0 Q9UK58 CCNL1_HUMAN Cyclin-L1 (Cyclin-L) CCNL1 BM-001 UNQ530/PRO1073 Homo sapiens (Human) regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of centrosome cycle [GO:0046605]; regulation of RNA splicing [GO:0043484]; regulation of transcription by RNA polymerase II [GO:0006357] cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; nuclear speck [GO:0016607]; nucleus [GO:0005634] cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538] 0.96935 -5.7173 HHGGSRSGHGRHR 0 0 0 0 9.51981 0 0 0 0 0 0 9.09722 0 0 0 0 0 0 0 0 0 0 0 0 9.01603 9.03174 8.92538 Q9UK59 DBR1_HUMAN Lariat debranching enzyme (EC 3.1.4.-) DBR1 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; RNA splicing, via transesterification reactions [GO:0000375]" nucleoplasm [GO:0005654]; nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA lariat debranching enzyme activity [GO:0008419] 0.62413 0.41489 LSDEHEPEQRKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.837 0 Q9UK61 TASOR_HUMAN Protein TASOR (CTCL tumor antigen se89-1) (Retinoblastoma-associated protein RAP140) (Transgene activation suppressor protein) TASOR C3orf63 FAM208A KIAA1105 Homo sapiens (Human) "anterior/posterior axis specification, embryo [GO:0008595]; mesodermal to mesenchymal transition involved in gastrulation [GO:0060809]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309]; protein localization to heterochromatin [GO:0097355]" heterochromatin [GO:0000792]; nucleoplasm [GO:0005654] chromatin binding [GO:0003682]; RNA binding [GO:0003723] 0.96827 -2.7609 ALGLSTDDAYEELRQK 11.2215 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1013 0 0 0 0 0 0 0 0 0 0 0 Q9UK73 FEM1B_HUMAN Protein fem-1 homolog B (FEM1b) (FEM1-beta) (Fem-1-like death receptor-binding protein alpha) (Fem-1-like in apoptotic pathway protein alpha) (F1A-alpha) FEM1B F1AA KIAA0396 Homo sapiens (Human) apoptotic process [GO:0006915]; branching involved in prostate gland morphogenesis [GO:0060442]; epithelial cell maturation involved in prostate gland development [GO:0060743]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of DNA damage checkpoint [GO:2000001]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of ubiquitin-protein transferase activity [GO:0051438]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] Cul2-RING ubiquitin ligase complex [GO:0031462]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] death receptor binding [GO:0005123]; ubiquitin ligase-substrate adaptor activity [GO:1990756] 0.91653 -0.76598 APDIECVLR 0 0 0 0 0 0 0 0 0 0 0 9.60722 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UK76 JUPI1_HUMAN "Jupiter microtubule associated homolog 1 (Androgen-regulated protein 2) (Hematological and neurological expressed 1 protein) [Cleaved into: Jupiter microtubule associated homolog 1, N-terminally processed]" JPT1 ARM2 HN1 Homo sapiens (Human) cytoplasm [GO:0005737]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.050633 1.423 GVDPNSR 0 0 0 8.28212 0 0 0 0 0 10.3025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UK80 UBP21_HUMAN Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.4.19.12) (Deubiquitinating enzyme 21) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) USP21 USP23 PP1490 Homo sapiens (Human) protein deubiquitination [GO:0016579]; transcription initiation-coupled chromatin remodeling [GO:0045815]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] cysteine-type deubiquitinase activity [GO:0004843]; cysteine-type peptidase activity [GO:0008234]; deNEDDylase activity [GO:0019784]; metal ion binding [GO:0046872]; transcription coactivator activity [GO:0003713] 0.97004 -4.3957 KGFAGGKVSLR 0 0 0 9.97885 0 0 0 0 0 0 0 0 0 0 0 0 9.53271 0 0 9.63497 0 0 0 0 0 0 0 Q9UK99 FBX3_HUMAN F-box only protein 3 FBXO3 FBX3 Homo sapiens (Human) protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; response to lipopolysaccharide [GO:0032496]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; SCF ubiquitin ligase complex [GO:0019005] ubiquitin ligase-substrate adaptor activity [GO:1990756]; ubiquitin-protein transferase activity [GO:0004842] 0.42111 0.67243 EEDLDAVEAQIGCK 0 0 0 0 0 0 10.6839 0 0 0 0 0 0 9.43471 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UKA2 FBXL4_HUMAN F-box/LRR-repeat protein 4 (F-box and leucine-rich repeat protein 4) (F-box protein FBL4/FBL5) FBXL4 FBL4 FBL5 Homo sapiens (Human) autophagy of mitochondrion [GO:0000422]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent protein catabolic process [GO:0006511] cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; nuclear speck [GO:0016607]; SCF ubiquitin ligase complex [GO:0019005]; ubiquitin ligase complex [GO:0000151] 0.93368 -1.2897 DGCGMDSLNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.41802 0 0 0 0 0 10.5967 Q9UKA4 AKA11_HUMAN A-kinase anchor protein 11 (AKAP-11) (A-kinase anchor protein 220 kDa) (AKAP 220) (hAKAP220) (Protein kinase A-anchoring protein 11) (PRKA11) AKAP11 AKAP220 KIAA0629 Homo sapiens (Human) cortical actin cytoskeleton organization [GO:0030866]; intracellular signal transduction [GO:0035556]; protein localization [GO:0008104]; protein localization to endosome [GO:0036010]; renal water homeostasis [GO:0003091] cytoplasm [GO:0005737]; cytosol [GO:0005829]; microtubule organizing center [GO:0005815]; nucleolus [GO:0005730]; plasma membrane [GO:0005886] protein kinase A binding [GO:0051018]; protein kinase A regulatory subunit binding [GO:0034237]; protein phosphatase 1 binding [GO:0008157] 0.88529 -0.38203 GVSSCTNALYHLAIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0133 0 0 0 0 0 0 0 0 0 0 0 Q9UKA8 RCAN3_HUMAN Calcipressin-3 (Down syndrome candidate region 1-like protein 2) (Myocyte-enriched calcineurin-interacting protein 3) (MCIP3) (Regulator of calcineurin 3) RCAN3 DSCR1L2 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; calcium-mediated signaling [GO:0019722] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634] calcium-dependent protein serine/threonine phosphatase regulator activity [GO:0008597]; phosphatase binding [GO:0019902]; RNA binding [GO:0003723]; troponin I binding [GO:0031013] 0.8975 -0.67908 LYFAQVQMSGEVRDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.82173 0 0 0 0 0 0 0 Q9UKB1 FBW1B_HUMAN F-box/WD repeat-containing protein 11 (F-box and WD repeats protein beta-TrCP2) (F-box/WD repeat-containing protein 1B) (Homologous to Slimb protein) (HOS) FBXW11 BTRCP2 FBW1B FBXW1B KIAA0696 Homo sapiens (Human) brain morphogenesis [GO:0048854]; establishment of mitotic spindle orientation [GO:0000132]; germ cell development [GO:0007281]; microtubule organizing center organization [GO:0031023]; negative regulation of DNA-templated transcription [GO:0045892]; nuclear migration [GO:0007097]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of proteolysis [GO:0045862]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein dephosphorylation [GO:0006470]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; retrograde axonal transport [GO:0008090]; rhythmic process [GO:0048511]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; vesicle transport along microtubule [GO:0047496]; Wnt signaling pathway [GO:0016055] axon cytoplasm [GO:1904115]; centrosome [GO:0005813]; cytoplasmic microtubule [GO:0005881]; cytosol [GO:0005829]; kinetochore [GO:0000776]; microtubule associated complex [GO:0005875]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; ubiquitin ligase complex [GO:0000151] dynein complex binding [GO:0070840]; microtubule plus-end binding [GO:0051010]; protein dimerization activity [GO:0046983]; ubiquitin-protein transferase activity [GO:0004842] 0.92371 -0.94766 CGRHNLQRIQCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1888 10.2184 Q9UKB3 DJC12_HUMAN DnaJ homolog subfamily C member 12 (J domain-containing protein 1) DNAJC12 JDP1 Homo sapiens (Human) cytoplasm [GO:0005737] 0.92455 -0.95485 EILTNEESR 0 0 8.57637 0 0 0 0 0 0 10.2234 10.6041 10.4483 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UKD2 MRT4_HUMAN mRNA turnover protein 4 homolog (Ribosome assembly factor MRTO4) MRTO4 C1orf33 MRT4 Homo sapiens (Human) nuclear-transcribed mRNA catabolic process [GO:0000956]; ribosomal large subunit assembly [GO:0000027]; ribosomal large subunit biogenesis [GO:0042273]; rRNA processing [GO:0006364] "cytoplasm [GO:0005737]; nucleolus [GO:0005730]; preribosome, large subunit precursor [GO:0030687]" RNA binding [GO:0003723] 0.9173 -0.85162 LRGEVGLLFTNRTK 0 0 0 0 0 0 0 0 0 0 0 11.1442 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UKE5 TNIK_HUMAN TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1) TNIK KIAA0551 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; microvillus assembly [GO:0030033]; neuron projection morphogenesis [GO:0048812]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein phosphorylation [GO:0001934]; protein autophosphorylation [GO:0046777]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; regulation of dendrite morphogenesis [GO:0048814]; regulation of MAPK cascade [GO:0043408]; response to organonitrogen compound [GO:0010243]; Wnt signaling pathway [GO:0016055] "apical plasma membrane [GO:0016324]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic density, intracellular component [GO:0099092]; presynapse [GO:0098793]; recycling endosome [GO:0055037]" ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.8895 -0.44777 AIDEDLTALAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.95629 0 0 0 Q9UKF5 ADA29_HUMAN Disintegrin and metalloproteinase domain-containing protein 29 (ADAM 29) (Cancer/testis antigen 73) (CT73) ADAM29 Homo sapiens (Human) male gonad development [GO:0008584]; proteolysis [GO:0006508]; spermatogenesis [GO:0007283] external side of plasma membrane [GO:0009897]; plasma membrane [GO:0005886]; sperm head plasma membrane [GO:1990913] metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237] 0.96809 -2.922 GYCYEKSCHDRNEQCR 0 0 0 0 0 0 0 0 0 0 10.612 0 10.7968 8.18898 0 0 0 0 0 0 0 0 8.53978 0 0 0 0 Q9UKG9 OCTC_HUMAN Peroxisomal carnitine O-octanoyltransferase (COT) (EC 2.3.1.137) CROT COT Homo sapiens (Human) carnitine metabolic process [GO:0009437]; coenzyme A metabolic process [GO:0015936]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; generation of precursor metabolites and energy [GO:0006091]; medium-chain fatty acid metabolic process [GO:0051791] cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777] carnitine O-octanoyltransferase activity [GO:0008458] 0.96774 -2.3462 IFQNEGRWK 0 0 0 0 0 0 0 0 0 0 9.36094 0 0 0 0 0 0 0 0 0 0 0 0 10.1085 0 11.4162 0 Q9UKJ0 PILRB_HUMAN Paired immunoglobulin-like type 2 receptor beta (Activating receptor PILR-beta) (Cell surface receptor FDFACT) PILRB FDFACT PP1551 Homo sapiens (Human) activation of transmembrane receptor protein tyrosine kinase activity [GO:0007171]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] plasma membrane [GO:0005886] MHC class I protein binding [GO:0042288] 0.90198 -0.69732 QQLQSIKGTK 0 0 0 0 0 0 0 0 0 9.47021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UKJ1 PILRA_HUMAN Paired immunoglobulin-like type 2 receptor alpha (Cell surface receptor FDF03) (Inhibitory receptor PILR-alpha) PILRA Homo sapiens (Human) signal transduction [GO:0007165] extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] MHC class I protein binding [GO:0042288] 0.89623 -0.54144 ISWRRGHFHR 14.5143 14.3311 0 0 12.7322 12.5829 0 14.0448 0 0 14.7538 10.7274 0 13.2483 13.1025 13.2185 13.4637 0 0 0 0 0 0 0 0 0 10.215 Q9UKJ3 GPTC8_HUMAN G patch domain-containing protein 8 GPATCH8 GPATC8 KIAA0553 Homo sapiens (Human) nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA binding [GO:0003723] 0.96249 -2.0321 ASEQMDGDNTTHPK 0 12.9582 8.50307 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UKJ8 ADA21_HUMAN Disintegrin and metalloproteinase domain-containing protein 21 (ADAM 21) (EC 3.4.24.-) ADAM21 Homo sapiens (Human) male gonad development [GO:0008584]; proteolysis [GO:0006508]; single fertilization [GO:0007338] axon [GO:0030424]; external side of plasma membrane [GO:0009897]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; sperm head plasma membrane [GO:1990913] metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237] 0.91783 -0.87523 EINSQGNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.92767 0 0 0 0 0 0 0 0 0 Q9UKK9 NUDT5_HUMAN ADP-sugar pyrophosphatase (EC 3.6.1.13) (8-oxo-dGDP phosphatase) (EC 3.6.1.58) (Nuclear ATP-synthesis protein NUDIX5) (EC 2.7.7.96) (Nucleoside diphosphate-linked moiety X motif 5) (Nudix motif 5) (hNUDT5) (YSA1H) NUDT5 NUDIX5 HSPC115 Homo sapiens (Human) ATP generation from poly-ADP-D-ribose [GO:1990966]; chromatin remodeling [GO:0006338]; D-ribose catabolic process [GO:0019303]; nucleobase-containing small molecule metabolic process [GO:0055086]; nucleoside phosphate metabolic process [GO:0006753]; nucleotide metabolic process [GO:0009117]; ribonucleoside diphosphate catabolic process [GO:0009191]; ribose phosphate metabolic process [GO:0019693] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634] 8-oxo-dGDP phosphatase activity [GO:0044715]; 8-oxo-GDP phosphatase activity [GO:0044716]; ADP-ribose diphosphatase activity [GO:0047631]; ADP-sugar diphosphatase activity [GO:0019144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; snoRNA binding [GO:0030515] 0.16558 0.97606 ELEEETGYK 0 0 0 0 0 0 9.99605 0 0 0 8.6453 0 10.4814 0 0 0 0 0 0 0 0 0 0 0 0 10.4422 0 Q9UKL0 RCOR1_HUMAN REST corepressor 1 (Protein CoREST) RCOR1 KIAA0071 RCOR Homo sapiens (Human) chromatin organization [GO:0006325]; erythrocyte differentiation [GO:0030218]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; positive regulation of megakaryocyte differentiation [GO:0045654]; regulation of transcription by RNA polymerase II [GO:0006357] DNA repair complex [GO:1990391]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667]; transcription repressor complex [GO:0017053] chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; transcription corepressor activity [GO:0003714] 0.96992 -5.0234 FYYSWKK 0 0 0 0 0 0 0 0 0 8.90989 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UKL3 C8AP2_HUMAN CASP8-associated protein 2 (FLICE-associated huge protein) CASP8AP2 FLASH KIAA1315 RIP25 Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic signaling pathway [GO:0097190]; cell cycle [GO:0007049]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; Fas signaling pathway [GO:0036337]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605] cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; death receptor binding [GO:0005123]; peptidase activator activity involved in apoptotic process [GO:0016505]; SUMO polymer binding [GO:0032184]; transcription corepressor activity [GO:0003714] 0.97015 -5.3391 AERHRTEDK 0 0 0 0 0 0 0 0 9.84447 0 0 10.3233 0 0 0 12.65 0 12.5792 0 0 0 0 0 9.92775 12.0475 12.7313 12.0752 Q9UKM7 MA1B1_HUMAN "Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (ER mannosidase 1) (ERMan1) (Man9GlcNAc2-specific-processing alpha-mannosidase) (Mannosidase alpha class 1B member 1)" MAN1B1 UNQ747/PRO1477 Homo sapiens (Human) "endoplasmic reticulum mannose trimming [GO:1904380]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; N-glycan processing [GO:0006491]; oligosaccharide metabolic process [GO:0009311]; protein alpha-1,2-demannosylation [GO:0036508]; protein glycosylation [GO:0006486]; trimming of first mannose on A branch [GO:0036511]; trimming of second mannose on A branch [GO:0036512]; trimming of terminal mannose on B branch [GO:0036509]; trimming of terminal mannose on C branch [GO:0036510]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral protein processing [GO:0019082]" cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum quality control compartment [GO:0044322]; extracellular vesicle [GO:1903561]; Golgi apparatus [GO:0005794]; membrane [GO:0016020] "calcium ion binding [GO:0005509]; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [GO:0004571]" 0.95982 -1.7276 ALAFRLEEEQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2951 0 0 0 0 0 0 9.89464 0 0 0 Q9UKN1 MUC12_HUMAN Mucin-12 (MUC-12) (Mucin-11) (MUC-11) MUC12 MUC11 Homo sapiens (Human) regulation of cell growth [GO:0001558] Golgi lumen [GO:0005796]; plasma membrane [GO:0005886] 0.96237 -2.5177 LACVNKCTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.48718 0 10.132 11.2105 0 0 0 Q9UKN7 MYO15_HUMAN Unconventional myosin-XV (Unconventional myosin-15) MYO15A MYO15 Homo sapiens (Human) actin filament organization [GO:0007015]; inner ear morphogenesis [GO:0042472]; locomotory behavior [GO:0007626]; response to light stimulus [GO:0009416]; sensory perception of sound [GO:0007605]; vesicle transport along actin filament [GO:0030050] actin cytoskeleton [GO:0015629]; actin-based cell projection [GO:0098858]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; myosin complex [GO:0016459]; stereocilium [GO:0032420]; vesicle [GO:0031982] actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; cytoskeletal motor activity [GO:0003774] 0.9696 -4.7902 ALSAFGAHR 10.4285 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2961 0 9.26796 0 0 Q9UKN8 TF3C4_HUMAN General transcription factor 3C polypeptide 4 (EC 2.3.1.48) (TF3C-delta) (Transcription factor IIIC 90 kDa subunit) (TFIIIC 90 kDa subunit) (TFIIIC90) (Transcription factor IIIC subunit delta) GTF3C4 Homo sapiens (Human) 5S class rRNA transcription by RNA polymerase III [GO:0042791]; transcription by RNA polymerase III [GO:0006383]; transcription initiation at RNA polymerase III promoter [GO:0006384]; tRNA transcription by RNA polymerase III [GO:0042797] mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; transcription factor TFIIIC complex [GO:0000127] DNA binding [GO:0003677]; enzyme activator activity [GO:0008047]; histone acetyltransferase activity [GO:0004402]; RNA polymerase III general transcription initiation factor activity [GO:0000995] 0.89668 -0.53894 ILPVNLKAVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5557 0 0 Q9UKP4 ATS7_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase) ADAMTS7 Homo sapiens (Human) cellular response to BMP stimulus [GO:0071773]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chondrocyte differentiation [GO:0002062]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; negative regulation of chondrocyte differentiation [GO:0032331]; ossification involved in bone maturation [GO:0043931]; proteoglycan metabolic process [GO:0006029]; proteolysis involved in protein catabolic process [GO:0051603] cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576] metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237] 0.86447 0.077172 GVQRQNVYCLER 0 0 0 8.84778 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UKP6 UR2R_HUMAN Urotensin-2 receptor (UR-2-R) (G-protein coupled receptor 14) (Urotensin II receptor) (UR-II-R) UTS2R GPR14 Homo sapiens (Human) blood circulation [GO:0008015]; blood vessel diameter maintenance [GO:0097746]; neuropeptide signaling pathway [GO:0007218]; regulation of blood pressure [GO:0008217]; signal transduction [GO:0007165] membrane [GO:0016020]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; urotensin II receptor activity [GO:0001604] 0.6605 0.39482 GPGSGGGR 0 0 0 0 0 0 0 0 8.78918 10.6769 0 10.6939 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UKR0 KLK12_HUMAN Kallikrein-12 (EC 3.4.21.-) (Kallikrein-like protein 5) (KLK-L5) KLK12 KLKL5 UNQ669/PRO1303 Homo sapiens (Human) proteolysis [GO:0006508] extracellular region [GO:0005576]; extracellular space [GO:0005615] peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236] 0.84245 0.14912 LGEHSLSQLDWTEQIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.99605 0 0 0 0 0 0 Q9UKR5 ERG28_HUMAN Ergosterol biosynthetic protein 28 homolog ERG28 C14orf1 AD-011 HSPC288 x0006 Homo sapiens (Human) sterol biosynthetic process [GO:0016126] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; transport vesicle [GO:0030133] identical protein binding [GO:0042802]; protein-macromolecule adaptor activity [GO:0030674] 0.54696 0.57342 YLEVEPVSR 0 0 0 0 0 0 8.99997 0 0 0 0 0 0 0 0 0 0 0 0 9.32798 0 0 0 9.95641 9.78351 0 0 Q9UKS6 PACN3_HUMAN Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) PACSIN3 Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endocytosis [GO:0006897]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endocytosis [GO:0045806]; plasma membrane tubulation [GO:0097320]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; regulation of endocytosis [GO:0030100] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] calcium channel inhibitor activity [GO:0019855]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; phospholipid binding [GO:0005543] 0.9591 -1.9578 LKEVEASKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9913 0 0 0 0 0 0 Q9UKT5 FBX4_HUMAN F-box only protein 4 FBXO4 FBX4 Homo sapiens (Human) cellular homeostasis [GO:0019725]; cellular response to ionizing radiation [GO:0071479]; cellular senescence [GO:0090398]; common myeloid progenitor cell proliferation [GO:0035726]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of protein localization to nucleus [GO:1900181]; positive regulation of protein polyubiquitination [GO:1902916]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of telomere maintenance via telomerase [GO:0032212]; post-transcriptional regulation of gene expression [GO:0010608]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA damage checkpoint [GO:2000001]; regulation of protein stability [GO:0031647]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; telomere maintenance [GO:0000723]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737]; cytosol [GO:0005829]; SCF ubiquitin ligase complex [GO:0019005]; ubiquitin ligase complex [GO:0000151] protein homodimerization activity [GO:0042803]; ubiquitin ligase-substrate adaptor activity [GO:1990756]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.80138 0.23946 DLPSWSSVDWK 0 0 0 0 0 0 0 0 0 0 0 9.21062 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UKT8 FBXW2_HUMAN F-box/WD repeat-containing protein 2 (F-box and WD-40 domain-containing protein 2) (Protein MD6) FBXW2 FBW2 FWD2 Homo sapiens (Human) protein modification process [GO:0036211]; proteolysis [GO:0006508] cytosol [GO:0005829] ubiquitin-protein transferase activity [GO:0004842] 0.89908 -0.6858 IWPIGREINCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.54971 0 0 0 0 0 Q9UKT9 IKZF3_HUMAN Zinc finger protein Aiolos (Ikaros family zinc finger protein 3) IKZF3 ZNFN1A3 Homo sapiens (Human) B cell differentiation [GO:0030183]; mesoderm development [GO:0007498]; regulation of apoptotic process [GO:0042981]; regulation of B cell differentiation [GO:0045577]; regulation of B cell proliferation [GO:0030888]; regulation of lymphocyte differentiation [GO:0045619]; regulation of transcription by RNA polymerase II [GO:0006357]; response to bacterium [GO:0009617]; T cell differentiation [GO:0030217] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]" 0.022272 1.5606 DPFECNMCGYR 9.04988 0 0 0 0 0 0 0 9.40508 0 9.91112 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5647 0 Q9UKU0 ACSL6_HUMAN Long-chain-fatty-acid--CoA ligase 6 (EC 6.2.1.3) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 6) (LACS 6) ACSL6 ACS2 FACL6 KIAA0837 LACS5 Homo sapiens (Human) acyl-CoA metabolic process [GO:0006637]; long-chain fatty acid metabolic process [GO:0001676]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; neuroblast proliferation [GO:0007405]; very long-chain fatty acid metabolic process [GO:0000038] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; plasma membrane [GO:0005886] arachidonate-CoA ligase activity [GO:0047676]; ATP binding [GO:0005524]; enzyme binding [GO:0019899]; long-chain fatty acid-CoA ligase activity [GO:0004467]; protein homodimerization activity [GO:0042803] 0.95889 -1.7161 LLNRMYDK 0 0 0 0 0 0 0 0 8.79666 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UKU6 TRHDE_HUMAN Thyrotropin-releasing hormone-degrading ectoenzyme (TRH-DE) (TRH-degrading ectoenzyme) (EC 3.4.19.6) (Pyroglutamyl-peptidase II) (PAP-II) (TRH-specific aminopeptidase) (Thyroliberinase) TRHDE UNQ2507/PRO5995 Homo sapiens (Human) cell-cell signaling [GO:0007267]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] aminopeptidase activity [GO:0004177]; metalloaminopeptidase activity [GO:0070006]; peptide binding [GO:0042277]; pyroglutamyl-peptidase activity [GO:0016920]; zinc ion binding [GO:0008270] 0.96349 -2.6794 NRIPLNVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9393 0 0 0 10.2667 0 0 0 0 0 Q9UKU7 ACAD8_HUMAN "Isobutyryl-CoA dehydrogenase, mitochondrial (IBDH) (EC 1.3.8.-) (Activator-recruited cofactor 42 kDa component) (ARC42) (Acyl-CoA dehydrogenase family member 8) (ACAD-8)" ACAD8 ARC42 IBD Homo sapiens (Human) lipid metabolic process [GO:0006629]; valine catabolic process [GO:0006574] mitochondrial matrix [GO:0005759] acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660] 0.5963 0.44602 DYAVQQYVR 0 8.41126 0 8.65793 0 0 8.65349 8.86576 9.14139 0 0 0 9.78767 11.7248 0 9.23112 11.027 0 0 9.87738 0 9.64681 9.8798 10.9309 9.54986 10.3183 10.1147 Q9UKV0 HDAC9_HUMAN Histone deacetylase 9 (HD9) (EC 3.5.1.98) (Histone deacetylase 7B) (HD7) (HD7b) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR) HDAC9 HDAC7 HDAC7B HDRP KIAA0744 MITR Homo sapiens (Human) "B cell activation [GO:0042113]; B cell differentiation [GO:0030183]; cellular response to insulin stimulus [GO:0032869]; cholesterol homeostasis [GO:0042632]; heart development [GO:0007507]; histone H4-K16 deacetylation [GO:1990678]; inflammatory response [GO:0006954]; negative regulation of cytokine production [GO:0001818]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of lipoprotein lipase activity [GO:0051005]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; regulation of skeletal muscle fiber development [GO:0048742]; regulation of striated muscle cell differentiation [GO:0051153]; response to amphetamine [GO:0001975]" cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] DNA-binding transcription factor binding [GO:0140297]; histone deacetylase activity [GO:0004407]; histone deacetylase binding [GO:0042826]; histone H3K14 deacetylase activity [GO:0031078]; histone H3K9 deacetylase activity [GO:0032129]; histone H4K16 deacetylase activity [GO:0034739]; metal ion binding [GO:0046872]; protein kinase C binding [GO:0005080]; protein lysine deacetylase activity [GO:0033558]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription corepressor activity [GO:0003714] 0.96158 -2.0252 ERAVASTEVK 0 0 9.85681 0 0 0 0 0 0 0 0 0 0 0 8.83194 0 0 0 0 0 0 0 0 0 0 0 0 Q9UKV3 ACINU_HUMAN Apoptotic chromatin condensation inducer in the nucleus (Acinus) ACIN1 ACINUS KIAA0670 Homo sapiens (Human) "apoptotic chromosome condensation [GO:0030263]; erythrocyte differentiation [GO:0030218]; mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of apoptotic process [GO:0043065]; positive regulation of monocyte differentiation [GO:0045657]; RNA splicing [GO:0008380]" ASAP complex [GO:0061574]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] ATP hydrolysis activity [GO:0016887]; enzyme binding [GO:0019899]; nucleic acid binding [GO:0003676]; RNA binding [GO:0003723] 0.96393 -2.3861 AESPAEK 0 0 0 0 0 10.3144 0 0 9.53128 12.0789 0 0 0 0 0 0 0 0 0 0 8.94805 0 0 0 10.8754 0 0 Q9UKV8 AGO2_HUMAN Protein argonaute-2 (Argonaute2) (hAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (PAZ Piwi domain protein) (PPD) (Protein slicer) AGO2 EIF2C2 Homo sapiens (Human) "miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; miRNA-mediated gene silencing by mRNA destabilization [GO:0035279]; ncRNA-mediated post-transcriptional gene silencing [GO:0035194]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of translational initiation [GO:0045947]; positive regulation of angiogenesis [GO:0045766]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of trophoblast cell migration [GO:1901165]; post-embryonic development [GO:0009791]; pre-miRNA processing [GO:0031054]; RISC complex assembly [GO:0070922]; RNA secondary structure unwinding [GO:0010501]; RNA-mediated gene silencing [GO:0031047]; siRNA processing [GO:0030422]; siRNA-mediated gene silencing by mRNA destabilization [GO:0090625]; translation [GO:0006412]" cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mRNA cap binding complex [GO:0005845]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; polysome [GO:0005844]; ribonucleoprotein complex [GO:1990904]; RISC complex [GO:0016442]; RISC-loading complex [GO:0070578] "core promoter sequence-specific DNA binding [GO:0001046]; double-stranded RNA binding [GO:0003725]; endoribonuclease activity, cleaving miRNA-paired mRNA [GO:0090624]; endoribonuclease activity, cleaving siRNA-paired mRNA [GO:0070551]; metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA cap binding [GO:0098808]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA endonuclease activity [GO:0004521]; RNA polymerase II complex binding [GO:0000993]; single-stranded RNA binding [GO:0003727]; siRNA binding [GO:0035197]; translation initiation factor activity [GO:0003743]" 0.92145 -0.93416 DRIFKVSIK 0 0 0 0 0 0 0 0 0 11.5928 0 0 0 0 0 0 0 0 0 9.77375 0 9.51706 0 0 0 0 0 Q9UKW4 VAV3_HUMAN Guanine nucleotide exchange factor VAV3 (VAV-3) VAV3 Homo sapiens (Human) angiogenesis [GO:0001525]; B cell receptor signaling pathway [GO:0050853]; cell migration [GO:0016477]; DNA damage response [GO:0006974]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; lamellipodium assembly [GO:0030032]; neutrophil chemotaxis [GO:0030593]; platelet activation [GO:0030168]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell adhesion [GO:0045785]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; response to xenobiotic stimulus [GO:0009410]; small GTPase mediated signal transduction [GO:0007264]; vesicle fusion [GO:0006906] cytoplasm [GO:0005737]; cytosol [GO:0005829]; immunological synapse [GO:0001772]; plasma membrane [GO:0005886] epidermal growth factor receptor binding [GO:0005154]; GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; metal ion binding [GO:0046872] 0.56522 0.5044 EIIDLQQYK 0 0 0 0 0 10.8025 0 0 0 0 0 0 0 10.2885 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UKW6 ELF5_HUMAN ETS-related transcription factor Elf-5 (E74-like factor 5) (Epithelium-restricted ESE-1-related Ets factor) (Epithelium-specific Ets transcription factor 2) (ESE-2) ELF5 ESE2 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.92166 -1.0992 KNDRMTYEK 0 8.53675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UKX2 MYH2_HUMAN "Myosin-2 (Myosin heavy chain 2) (Myosin heavy chain 2a) (MyHC-2a) (Myosin heavy chain IIa) (MyHC-IIa) (Myosin heavy chain, skeletal muscle, adult 2)" MYH2 MYHSA2 Homo sapiens (Human) muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049] cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; muscle myosin complex [GO:0005859]; myofibril [GO:0030016]; myosin filament [GO:0032982]; myosin II complex [GO:0016460]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017] actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; microfilament motor activity [GO:0000146] 0.96859 -5.8115 ADIAESQVNK 0 0 10.7378 8.90722 8.852 0 0 0 0 11.8411 9.14741 0 9.51262 10.9516 10.7368 9.96622 10.03 9.92449 10.2441 10.6493 9.02306 0 9.66448 0 0 10.9351 10.9088 Q9UKX3 MYH13_HUMAN "Myosin-13 (Myosin heavy chain 13) (Myosin heavy chain, skeletal muscle, extraocular) (MyHC-EO) (Myosin heavy chain, skeletal muscle, laryngeal) (MyHC-IIL) (Superfast myosin)" MYH13 Homo sapiens (Human) cellular response to starvation [GO:0009267]; muscle contraction [GO:0006936] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; muscle myosin complex [GO:0005859]; myofibril [GO:0030016]; myosin filament [GO:0032982]; myosin II complex [GO:0016460] actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; microfilament motor activity [GO:0000146] 0.5664 0.49147 ADIAESQVNK 0 0 0 0 8.57429 0 0 0 10.2746 9.76951 0 0 0 0 0 0 0 0 0 10.0415 0 0 0 0 0 0 0 Q9UKX5 ITA11_HUMAN Integrin alpha-11 ITGA11 MSTP018 Homo sapiens (Human) cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; collagen-activated signaling pathway [GO:0038065]; integrin-mediated signaling pathway [GO:0007229]; muscle organ development [GO:0007517]; osteoblast differentiation [GO:0001649]; substrate-dependent cell migration [GO:0006929] external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha11-beta1 complex [GO:0034681]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886] collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; collagen receptor activity [GO:0038064]; integrin binding [GO:0005178]; metal ion binding [GO:0046872] 0.95171 -1.4226 GINPETFLNEIK 0 0 0 9.86471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5586 0 0 Q9UKY0 PRND_HUMAN Prion-like protein doppel (PrPLP) (Prion protein 2) PRND DPL UNQ1830/PRO3443 Homo sapiens (Human) acrosome reaction [GO:0007340]; intracellular copper ion homeostasis [GO:0006878]; protein homooligomerization [GO:0051260] external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; plasma membrane [GO:0005886] copper ion binding [GO:0005507] 0.75943 0.29341 LVQELCSLKHCEFWLER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.35436 0 0 Q9UKY7 CDV3_HUMAN Protein CDV3 homolog CDV3 H41 Homo sapiens (Human) cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886] 0.96117 -2.021 EVDYSGLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6027 8.77116 Q9UKZ1 CNO11_HUMAN CCR4-NOT transcription complex subunit 11 CNOT11 C2orf29 C40 Homo sapiens (Human) nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; RNA-mediated gene silencing [GO:0031047] CCR4-NOT complex [GO:0030014]; cytosol [GO:0005829]; nucleus [GO:0005634] 0.84135 0.14428 LLTAAEQRGSR 0 0 9.53852 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.04089 0 0 0 Q9UKZ4 TEN1_HUMAN Teneurin-1 (Ten-1) (Protein Odd Oz/ten-m homolog 1) (Tenascin-M1) (Ten-m1) (Teneurin transmembrane protein 1) [Cleaved into: Ten-1 intracellular domain (IDten-1) (Ten-1 ICD); Teneurin C-terminal-associated peptide (TCPA-1) (Ten-1 extracellular domain) (Ten-1 ECD)] TENM1 ODZ1 TNM1 Homo sapiens (Human) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; immune response [GO:0006955]; negative regulation of cell population proliferation [GO:0008285]; nervous system development [GO:0007399]; neuron development [GO:0048666]; neuropeptide signaling pathway [GO:0007218]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; regulation of transcription by RNA polymerase III [GO:0006359] cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; neuron projection [GO:0043005]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] cell adhesion molecule binding [GO:0050839]; heparin binding [GO:0008201]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803] 0.96981 -4.9889 FSEEGLVNAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0937 0 10.4474 0 8.84276 Q9UKZ9 PCOC2_HUMAN Procollagen C-endopeptidase enhancer 2 (Procollagen COOH-terminal proteinase enhancer 2) (PCPE-2) (Procollagen C-proteinase enhancer 2) PCOLCE2 PCPE2 UNQ250/PRO287 Homo sapiens (Human) cellular response to leukemia inhibitory factor [GO:1990830] extracellular region [GO:0005576] collagen binding [GO:0005518]; heparin binding [GO:0008201]; peptidase activator activity [GO:0016504] 0.95321 -1.4825 FEKFDVER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1624 0 0 Q9UL01 DSE_HUMAN Dermatan-sulfate epimerase (DS epimerase) (EC 5.1.3.19) (Chondroitin-glucuronate 5-epimerase) (Squamous cell carcinoma antigen recognized by T-cells 2) (SART-2) DSE SART2 Homo sapiens (Human) chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate metabolic process [GO:0030204]; dermatan sulfate biosynthetic process [GO:0030208]; dermatan sulfate metabolic process [GO:0030205]; heparan sulfate proteoglycan biosynthetic process [GO:0015012] cytoplasmic vesicle membrane [GO:0030659]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139] chondroitin-glucuronate 5-epimerase activity [GO:0047757]; metal ion binding [GO:0046872] 0.95502 -1.5631 AASSHEHIAAR 0 0 0 0 0 0 0 0 10.3763 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UL03 INT6_HUMAN Integrator complex subunit 6 (Int6) (DBI-1) (Protein DDX26) (Protein deleted in cancer 1) (DICE1) INTS6 DBI1 DDX26 DDX26A Homo sapiens (Human) regulation of transcription elongation by RNA polymerase II [GO:0034243]; snRNA 3'-end processing [GO:0034472]; snRNA processing [GO:0016180] actin cytoskeleton [GO:0015629]; integrator complex [GO:0032039]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] transmembrane signaling receptor activity [GO:0004888] 0.84053 0.14399 DFQQLLQGISEDVPHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9016 Q9UL12 SARDH_HUMAN "Sarcosine dehydrogenase, mitochondrial (SarDH) (EC 1.5.8.3) (BPR-2)" SARDH DMGDHL1 Homo sapiens (Human) sarcosine catabolic process [GO:1901053] cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] sarcosine dehydrogenase activity [GO:0008480] 0.91384 -0.77928 RADFGFAIDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2483 0 0 0 0 0 0 0 0 Q9UL16 CFA45_HUMAN Cilia- and flagella-associated protein 45 (Coiled-coil domain-containing protein 19) (Nasopharyngeal epithelium-specific protein 1) CFAP45 CCDC19 NESG1 Homo sapiens (Human) cerebrospinal fluid circulation [GO:0090660]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment of left/right asymmetry [GO:0061966]; flagellated sperm motility [GO:0030317]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296] 9+0 motile cilium [GO:0097728]; 9+2 motile cilium [GO:0097729]; axonemal microtubule [GO:0005879]; axoneme [GO:0005930]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] AMP binding [GO:0016208] 0.96311 -2.1232 KANILPATSVN 0 0 0 0 0 0 0 0 0 0 0 0 10.2417 0 0 0 0 0 0 0 0 0 9.10284 0 10.5753 0 0 Q9UL17 TBX21_HUMAN T-box transcription factor TBX21 (T-box protein 21) (T-cell-specific T-box transcription factor T-bet) (Transcription factor TBLYM) TBX21 TBET TBLYM Homo sapiens (Human) cell fate specification [GO:0001708]; cellular response to organic substance [GO:0071310]; lymphocyte migration [GO:0072676]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of T-helper 17 cell differentiation [GO:2000320]; negative regulation of T-helper 17 cell lineage commitment [GO:2000329]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of T cell differentiation [GO:0045580]; regulation of transcription by RNA polymerase II [GO:0006357]; response to virus [GO:0009615]; T-helper 1 cell lineage commitment [GO:0002296] neuronal cell body [GO:0043025]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]" 0.86816 0.071583 FNQHQTEMIITKQGR 0 0 0 0 0 0 11.3511 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UL25 RAB21_HUMAN Ras-related protein Rab-21 RAB21 KIAA0118 Homo sapiens (Human) anterograde axonal transport [GO:0008089]; intracellular protein transport [GO:0006886]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein stabilization [GO:0050821]; Rab protein signal transduction [GO:0032482]; regulation of axon extension [GO:0030516]; regulation of exocytosis [GO:0017157] axon cytoplasm [GO:1904115]; cleavage furrow [GO:0032154]; cytoplasmic side of early endosome membrane [GO:0098559]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endomembrane system [GO:0012505]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; synapse [GO:0045202]; trans-Golgi network [GO:0005802]; vesicle membrane [GO:0012506] GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.55875 0.53558 GIEELFLDLCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6328 0 0 0 0 0 9.58731 Q9UL26 RB22A_HUMAN Ras-related protein Rab-22A (Rab-22) RAB22A RAB22 Homo sapiens (Human) endocytosis [GO:0006897]; endosome organization [GO:0007032]; intracellular protein transport [GO:0006886]; regulation of vesicle size [GO:0097494] actin cytoskeleton [GO:0015629]; early endosome [GO:0005769]; endomembrane system [GO:0012505]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; late endosome [GO:0005770]; phagocytic vesicle [GO:0045335]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; ruffle [GO:0001726] GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.92262 -1.0567 EVMERDAK 0 0 0 0 0 0 0 0 8.88935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UL36 ZN236_HUMAN Zinc finger protein 236 ZNF236 Homo sapiens (Human) cellular response to glucose stimulus [GO:0071333]; regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96939 -4.0369 CEICLLSFPK 0 9.6435 0 10.7599 0 10.7571 0 0 0 0 0 0 0 0 0 0 0 9.46624 0 0 0 0 0 0 0 9.69125 9.51798 Q9UL40 ZN346_HUMAN Zinc finger protein 346 (Just another zinc finger protein) ZNF346 JAZ Homo sapiens (Human) cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] double-stranded RNA binding [GO:0003725]; enzyme binding [GO:0019899]; miRNA binding [GO:0035198]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270] 0.96971 -5.4462 EEVEHMIQKNQCLFTNTQCK 0 0 0 0 0 0 0 0 0 10.9811 0 0 9.84365 0 0 0 0 0 0 0 0 0 8.00826 0 0 0 0 Q9UL41 PNMA3_HUMAN Paraneoplastic antigen Ma3 PNMA3 MA3 Homo sapiens (Human) positive regulation of apoptotic process [GO:0043065] nucleolus [GO:0005730] nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270] 0.89761 -0.55128 AGSRGSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.37036 Q9UL49 TCFL5_HUMAN Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1) TCFL5 CHA E2BP1 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; regulation of DNA-templated transcription [GO:0006355]; spermatogenesis [GO:0007283]; transcription by RNA polymerase II [GO:0006366] chromatin [GO:0000785]; male germ cell nucleus [GO:0001673]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; protein dimerization activity [GO:0046983]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.92378 -1.0468 HNRMERDR 0 0 0 0 0 0 0 0 0 0 10.3065 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UL52 TM11E_HUMAN Transmembrane protease serine 11E (EC 3.4.21.-) (Serine protease DESC1) (Transmembrane protease serine 11E2) [Cleaved into: Transmembrane protease serine 11E non-catalytic chain; Transmembrane protease serine 11E catalytic chain] TMPRSS11E DESC1 TMPRSS11E2 UNQ742/PRO1461 Homo sapiens (Human) cognition [GO:0050890]; proteolysis [GO:0006508] extracellular region [GO:0005576]; plasma membrane [GO:0005886] serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236] 0.16423 0.97659 MLCAGSLEGK 10.9977 0 0 0 0 0 0 0 0 0 0 9.17165 9.01235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UL54 TAOK2_HUMAN Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) (hKFC-C) (Prostate-derived sterile 20-like kinase 1) (PSK-1) (PSK1) (Prostate-derived STE20-like kinase 1) (Thousand and one amino acid protein kinase 2) TAOK2 KIAA0881 MAP3K17 PSK PSK1 UNQ2971/PRO7431 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; activation of protein kinase activity [GO:0032147]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; basal dendrite arborization [GO:0150020]; basal dendrite morphogenesis [GO:0150019]; cell migration [GO:0016477]; DNA damage response [GO:0006974]; focal adhesion assembly [GO:0048041]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein targeting to membrane [GO:0006612]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell growth [GO:0001558]; regulation of cell shape [GO:0008360]; stress-activated MAPK cascade [GO:0051403] actin cytoskeleton [GO:0015629]; axon [GO:0030424]; axonal growth cone [GO:0044295]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; receptor complex [GO:0043235] ATP binding [GO:0005524]; MAP kinase kinase kinase activity [GO:0004709]; mitogen-activated protein kinase kinase binding [GO:0031434]; neuropilin binding [GO:0038191]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activator activity [GO:0043539]; protein serine/threonine kinase activity [GO:0004674]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321] 0.96986 -4.3611 DAVRELDNLQYRK 0 0 0 0 0 0 0 0 11.1537 0 0 0 0 0 11.5152 9.48438 0 0 0 0 0 0 0 0 9.75892 9.46111 0 Q9UL58 ZN215_HUMAN Zinc finger protein 215 (BWSCR2-associated zinc finger protein 2) (BAZ-2) (Zinc finger protein with KRAB and SCAN domains 11) ZNF215 BAZ2 ZKSCAN11 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.95982 -1.9276 HQKLHAEAK 0 0 0 0 0 9.17988 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UL62 TRPC5_HUMAN Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (TRP-5) (hTRP-5) (hTRP5) TRPC5 TRP5 Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; negative regulation of dendrite morphogenesis [GO:0050774]; nervous system development [GO:0007399]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; phosphatidylserine exposure on apoptotic cell surface [GO:0070782]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of membrane hyperpolarization [GO:1902630] calcium channel complex [GO:0034704]; cation channel complex [GO:0034703]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; growth cone [GO:0030426]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886] "actin binding [GO:0003779]; actinin binding [GO:0042805]; ATPase binding [GO:0051117]; calcium channel activity [GO:0005262]; clathrin binding [GO:0030276]; inositol 1,4,5 trisphosphate binding [GO:0070679]; store-operated calcium channel activity [GO:0015279]" 0.95169 -1.4437 KVNYSPYRDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.0227 0 0 0 0 Q9UL63 MKLN1_HUMAN Muskelin MKLN1 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; cell-matrix adhesion [GO:0007160]; regulation of cell shape [GO:0008360]; regulation of receptor internalization [GO:0002090]; signal transduction [GO:0007165] cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; postsynapse [GO:0098794]; ruffle [GO:0001726]; ubiquitin ligase complex [GO:0000151] identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803] 0.92728 -1.2189 IALEHPMLTDIHDK 0 0 0 0 0 0 0 11.4148 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4497 0 0 0 Q9UL68 MYT1L_HUMAN Myelin transcription factor 1-like protein (MyT1-L) (MyT1L) MYT1L KIAA1106 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; neuron fate specification [GO:0048665]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; zinc ion binding [GO:0008270]" 0.96937 -6.3798 AKAMREK 0 0 0 9.89853 0 0 10.128 0 0 9.13127 0 0 9.13904 0 0 0 0 0 0 0 0 9.08207 0 0 0 0 0 Q9ULB1 NRX1A_HUMAN Neurexin-1 (Neurexin I-alpha) (Neurexin-1-alpha) NRXN1 KIAA0578 Homo sapiens (Human) "adult behavior [GO:0030534]; axon guidance [GO:0007411]; chemical synaptic transmission [GO:0007268]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; learning [GO:0007612]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuromuscular process controlling balance [GO:0050885]; neuron cell-cell adhesion [GO:0007158]; neurotransmitter secretion [GO:0007269]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625]" cell projection [GO:0042995]; cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; vesicle [GO:0031982] acetylcholine receptor binding [GO:0033130]; calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor activity [GO:0038023] 0.88917 -0.44867 NNDVRLELSRLAK 0 0 0 0 0 0 0 0 0 0 9.03727 9.35484 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9ULB4 CADH9_HUMAN Cadherin-9 CDH9 Homo sapiens (Human) adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; synapse assembly [GO:0007416]; synaptic membrane adhesion [GO:0099560] adherens junction [GO:0005912]; catenin complex [GO:0016342]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734] cadherin binding [GO:0045296]; calcium ion binding [GO:0005509] 0.87117 0.062866 ISVEDIDEPPVFTK 0 0 0 0 9.54661 0 0 0 0 8.81794 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9ULB5 CADH7_HUMAN Cadherin-7 CDH7 CDH7L1 Homo sapiens (Human) adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] adherens junction [GO:0005912]; catenin complex [GO:0016342]; plasma membrane [GO:0005886] cadherin binding [GO:0045296]; calcium ion binding [GO:0005509] 0.92228 -1.1246 IEAANKDADPR 0 8.76772 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.68349 0 0 0 0 0 0 0 0 0 Q9ULC4 MCTS1_HUMAN Malignant T-cell-amplified sequence 1 (MCT-1) (Multiple copies T-cell malignancies) MCTS1 MCT1 Homo sapiens (Human) cell cycle [GO:0007049]; DNA damage response [GO:0006974]; formation of translation preinitiation complex [GO:0001731]; IRES-dependent viral translational initiation [GO:0075522]; positive regulation of cell population proliferation [GO:0008284]; ribosome disassembly [GO:0032790] cytoplasm [GO:0005737] RNA binding [GO:0003723]; translation initiation factor activity [GO:0003743] 0.56049 0.50711 EGPFYPTLR 0 0 0 0 0 0 0 8.958 0 0 0 0 0 0 9.89392 0 0 0 0 0 0 0 0 0 0 0 10.3712 Q9ULC5 ACSL5_HUMAN Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 5) (LACS 5) ACSL5 ACS5 FACL5 UNQ633/PRO1250 Homo sapiens (Human) long-chain fatty acid metabolic process [GO:0001676]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; positive regulation of long-chain fatty acid import across plasma membrane [GO:0010747]; regulation of extrinsic apoptotic signaling pathway [GO:2001236] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] arachidonate-CoA ligase activity [GO:0047676]; ATP binding [GO:0005524]; long-chain fatty acid-CoA ligase activity [GO:0004467] 0.96065 -2.0136 GEKSGIEILSLYDAENLGKEHFR 0 0 0 0 0 9.72952 0 0 0 0 0 0 0 0 0 0 9.80113 0 0 0 0 0 0 0 0 0 0 Q9ULC6 PADI1_HUMAN Protein-arginine deiminase type-1 (EC 3.5.3.15) (Peptidylarginine deiminase I) (Protein-arginine deiminase type I) PADI1 PAD1 PDI1 Homo sapiens (Human) cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654] calcium ion binding [GO:0005509]; protein-arginine deiminase activity [GO:0004668] 0.84903 0.11321 SINEMLADR 0 9.00666 8.34886 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9ULC8 ZDHC8_HUMAN Palmitoyltransferase ZDHHC8 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378) ZDHHC8 KIAA1292 ZDHHCL1 ZNF378 Homo sapiens (Human) high-density lipoprotein particle assembly [GO:0034380]; locomotory behavior [GO:0007626]; peptidyl-L-cysteine S-palmitoylation [GO:0018230]; positive regulation by host of viral process [GO:0044794]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein palmitoylation [GO:0018345] cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; mitochondrial membrane [GO:0031966]; synapse [GO:0045202] palmitoyltransferase activity [GO:0016409]; protein-cysteine S-palmitoyltransferase activity [GO:0019706] 0.93171 -1.2686 SKSKGSLDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2359 0 0 0 0 0 Q9ULD0 OGDHL_HUMAN "2-oxoglutarate dehydrogenase-like, mitochondrial (EC 1.2.4.2) (2-oxoglutarate dehydrogenase complex component E1-like) (OGDC-E1-like) (Alpha-ketoglutarate dehydrogenase-like)" OGDHL KIAA1290 Homo sapiens (Human) 2-oxoglutarate metabolic process [GO:0006103]; glycolytic process [GO:0006096]; tricarboxylic acid cycle [GO:0006099] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; oxoglutarate dehydrogenase complex [GO:0045252] metal ion binding [GO:0046872]; oxoglutarate dehydrogenase (succinyl-transferring) activity [GO:0004591]; thiamine pyrophosphate binding [GO:0030976] 0.97013 -4.2954 LSGQDVER 9.50999 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.75729 0 0 0 0 0 Q9ULD2 MTUS1_HUMAN Microtubule-associated tumor suppressor 1 (AT2 receptor-binding protein) (Angiotensin-II type 2 receptor-interacting protein) (Mitochondrial tumor suppressor 1) MTUS1 ATBP ATIP GK1 KIAA1288 MTSG1 Homo sapiens (Human) regulation of macrophage chemotaxis [GO:0010758] extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; microtubule organizing center [GO:0005815]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; spindle [GO:0005819] microtubule binding [GO:0008017] 0.96689 -2.842 MESAECLEMTYVPNIDR 12.1879 10.6491 9.91467 0 9.42127 0 0 0 10.9278 0 0 9.5004 0 9.18785 9.19098 10.3039 9.23367 9.10575 0 0 0 0 0 0 0 0 0 Q9ULD5 ZN777_HUMAN Zinc finger protein 777 ZNF777 KIAA1285 Homo sapiens (Human) negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; protein heterooligomerization [GO:0051291] nucleus [GO:0005634] DNA binding [GO:0003677]; metal ion binding [GO:0046872] 0.94625 -1.3505 LTNHCRVHSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.59908 0 0 9.80797 0 0 0 Q9ULD6 INTU_HUMAN Protein inturned (Inturned planar cell polarity effector homolog) (PDZ domain-containing protein 6) INTU KIAA1284 PDZD6 PDZK6 Homo sapiens (Human) cell division [GO:0051301]; cilium assembly [GO:0060271]; embryonic digit morphogenesis [GO:0042733]; establishment of planar polarity [GO:0001736]; hair follicle morphogenesis [GO:0031069]; intraciliary transport [GO:0042073]; keratinocyte differentiation [GO:0030216]; limb development [GO:0060173]; motile cilium assembly [GO:0044458]; negative regulation of cell division [GO:0051782]; negative regulation of keratinocyte proliferation [GO:0010839]; nervous system development [GO:0007399]; neural tube development [GO:0021915]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization to organelle [GO:0033365]; regulation of cilium assembly [GO:1902017]; regulation of ossification [GO:0030278]; regulation of smoothened signaling pathway [GO:0008589]; roof of mouth development [GO:0060021]; smoothened signaling pathway [GO:0007224]; spinal cord dorsal/ventral patterning [GO:0021513]; tongue morphogenesis [GO:0043587]; vesicle-mediated transport [GO:0016192] cell surface [GO:0009986]; centriole [GO:0005814]; ciliary basal body [GO:0036064]; ciliary transition zone [GO:0035869]; cilium [GO:0005929]; cytoplasm [GO:0005737]; motile cilium [GO:0031514] 0.96329 -2.1387 FSENEIIIEDDYK 0 0 0 0 0 0 9.32973 0 0 0 0 0 0 0 0 0 9.48784 0 10.0545 0 9.6097 0 0 0 0 11.2339 11.4321 Q9ULD8 KCNH3_HUMAN Potassium voltage-gated channel subfamily H member 3 (Brain-specific eag-like channel 1) (BEC1) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Voltage-gated potassium channel subunit Kv12.2) KCNH3 KIAA1282 Homo sapiens (Human) potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of membrane potential [GO:0042391]; regulation of monoatomic ion transmembrane transport [GO:0034765] membrane [GO:0016020]; plasma membrane [GO:0005886] voltage-gated potassium channel activity [GO:0005249] 0.96907 -4.4889 DISETKNR 0 0 0 0 0 0 0 0 0 0 0 9.67925 0 0 0 0 0 0 0 0 0 9.30191 0 0 0 0 0 Q9ULD9 ZN608_HUMAN Zinc finger protein 608 (Renal carcinoma antigen NY-REN-36) ZNF608 KIAA1281 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] metal ion binding [GO:0046872] 0.96946 -3.9664 DLPGHFLKDHLNK 0 0 0 0 10.6469 0 8.864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9ULE3 DEN2A_HUMAN DENN domain-containing protein 2A DENND2A KIAA1277 Homo sapiens (Human) "protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]" actin cytoskeleton [GO:0015629]; cytosol [GO:0005829] guanyl-nucleotide exchange factor activity [GO:0005085] 0.96003 -1.8969 DKISEWEGKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2599 0 0 0 0 0 0 0 Q9ULE4 F184B_HUMAN Protein FAM184B FAM184B KIAA1276 Homo sapiens (Human) 0.96964 -5.6244 EVEAQLEEVRK 8.93534 0 9.4412 0 0 0 0 0 0 0 10.2954 0 0 0 9.80379 0 0 0 0 0 0 0 9.36416 0 0 0 0 Q9ULE6 PALD_HUMAN Paladin PALD1 KIAA1274 PALD Homo sapiens (Human) cytosol [GO:0005829] 0.95952 -1.9116 EVVLENQKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1153 10.5781 0 0 0 0 0 0 0 0 0 Q9ULF5 S39AA_HUMAN Zinc transporter ZIP10 (Solute carrier family 39 member 10) (Zrt- and Irt-like protein 10) (ZIP-10) SLC39A10 KIAA1265 ZIP10 Homo sapiens (Human) epithelial to mesenchymal transition [GO:0001837]; intracellular monoatomic cation homeostasis [GO:0030003]; intracellular zinc ion homeostasis [GO:0006882]; negative regulation of B cell apoptotic process [GO:0002903]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of B cell receptor signaling pathway [GO:0050861]; positive regulation of protein tyrosine phosphatase activity [GO:1903615]; zinc ion import across plasma membrane [GO:0071578]; zinc ion transmembrane transport [GO:0071577] apical plasma membrane [GO:0016324]; plasma membrane [GO:0005886] monoatomic cation:bicarbonate symporter activity [GO:0140410]; zinc ion transmembrane transporter activity [GO:0005385] 0.89038 -0.49337 KDLNEDDHHHECLNVTQLLK 0 0 0 0 0 0 0 0 0 10.8602 0 0 0 0 0 0 9.48464 0 9.20596 0 0 0 0 0 0 0 0 Q9ULG1 INO80_HUMAN Chromatin-remodeling ATPase INO80 (hINO80) (EC 3.6.4.-) (DNA helicase-related INO80 complex homolog 1) (DNA helicase-related protein INO80) (INO80 complex subunit A) INO80 INO80A INOC1 KIAA1259 Homo sapiens (Human) cell division [GO:0051301]; cellular response to ionizing radiation [GO:0071479]; cellular response to UV [GO:0034644]; chromatin remodeling [GO:0006338]; DNA repair [GO:0006281]; DNA-templated transcription [GO:0006351]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; mitotic sister chromatid segregation [GO:0000070]; positive regulation of cell growth [GO:0030307]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of nuclear cell cycle DNA replication [GO:0010571]; positive regulation of telomere maintenance in response to DNA damage [GO:1904507]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of chromosome organization [GO:0033044]; regulation of DNA repair [GO:0006282]; regulation of DNA replication [GO:0006275]; regulation of DNA strand elongation [GO:0060382]; regulation of embryonic development [GO:0045995]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; spindle assembly [GO:0051225]; telomere maintenance [GO:0000723]; UV-damage excision repair [GO:0070914] cytosol [GO:0005829]; Ino80 complex [GO:0031011]; microtubule [GO:0005874]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819] "actin binding [GO:0003779]; alpha-tubulin binding [GO:0043014]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent activity, acting on DNA [GO:0008094]; ATP-dependent chromatin remodeler activity [GO:0140658]; DNA binding [GO:0003677]; histone binding [GO:0042393]" 0.96861 -3.6031 AKEKSEIQR 0 0 0 8.24151 0 0 8.95338 0 0 11.8541 9.94685 8.75495 0 0 0 0 9.62293 0 0 0 0 0 9.04772 9.44956 10.8428 0 0 Q9ULH0 KDIS_HUMAN Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein) KIDINS220 ARMS KIAA1250 Homo sapiens (Human) cellular response to nerve growth factor stimulus [GO:1990090]; dendrite morphogenesis [GO:0048813]; in utero embryonic development [GO:0001701]; nerve growth factor signaling pathway [GO:0038180]; positive regulation of neuron projection development [GO:0010976] cytosol [GO:0005829]; late endosome [GO:0005770]; membrane [GO:0016020]; protein-containing complex [GO:0032991] PDZ domain binding [GO:0030165]; protein kinase regulator activity [GO:0019887] 0.93355 -1.2831 GGHVEIVRALLQKYADIDIR 0 0 0 0 0 0 0 0 0 0 0 0 10.3515 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9ULH1 ASAP1_HUMAN "Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein) (ADP-ribosylation factor-directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (DEF-1) (Differentiation-enhancing factor 1) (PIP2-dependent ARF1 GAP)" ASAP1 DDEF1 KIAA1249 PAG2 Homo sapiens (Human) cilium assembly [GO:0060271]; negative regulation of dendritic spine development [GO:0061000]; positive regulation of GTPase activity [GO:0043547]; positive regulation of membrane tubulation [GO:1903527]; regulation of postsynapse organization [GO:0099175] cytosol [GO:0005829]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; podosome [GO:0002102] "cadherin binding [GO:0045296]; GTPase activator activity [GO:0005096]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]" 0.93918 -1.2962 EYITAKYVDHR 0 9.31463 10.6467 0 0 0 0 0 8.5509 0 0 0 0 0 0 0 8.40467 0 0 0 0 0 0 0 0 0 0 Q9ULI1 NWD2_HUMAN NACHT and WD repeat domain-containing protein 2 (Leucine-rich repeat and WD repeat-containing protein KIAA1239) NWD2 KIAA1239 Homo sapiens (Human) 0.9694 -4.625 GEIIYSLDGSDCVHKWNFSSGFIEAVFK 0 0 0 0 10.1792 8.72209 0 11.1447 0 0 0 0 0 0 0 0 0 0 0 7.98168 0 0 0 0 0 0 0 Q9ULI3 HEG1_HUMAN Protein HEG homolog 1 HEG1 KIAA1237 Homo sapiens (Human) cardiac atrium morphogenesis [GO:0003209]; cardiac muscle tissue growth [GO:0055017]; cell-cell junction organization [GO:0045216]; endothelial cell morphogenesis [GO:0001886]; heart development [GO:0007507]; in utero embryonic development [GO:0001701]; lung development [GO:0030324]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; multicellular organism growth [GO:0035264]; negative regulation of membrane permeability [GO:1905709]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of Rho-dependent protein serine/threonine kinase activity [GO:2000299]; pericardium development [GO:0060039]; positive regulation of fibroblast growth factor production [GO:0090271]; post-embryonic development [GO:0009791]; protein localization to cell junction [GO:1902414]; regulation of body fluid levels [GO:0050878]; vasculogenesis [GO:0001570]; venous blood vessel morphogenesis [GO:0048845]; ventricular septum development [GO:0003281]; ventricular trabecula myocardium morphogenesis [GO:0003222] cell-cell junction [GO:0005911]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576] calcium ion binding [GO:0005509] 0.95955 -1.8177 MQKCVNSCK 0 0 0 0 10.4266 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.4121 0 0 10.0411 Q9ULI4 KI26A_HUMAN Kinesin-like protein KIF26A KIF26A KIAA1236 Homo sapiens (Human) cerebral cortex development [GO:0021987]; enteric nervous system development [GO:0048484]; negative regulation of signal transduction [GO:0009968]; regulation of cell growth by extracellular stimulus [GO:0001560]; regulation of neuron migration [GO:2001222]; regulation of neuron projection development [GO:0010975] cytosol [GO:0005829]; microtubule [GO:0005874] ATP binding [GO:0005524]; microtubule binding [GO:0008017] 0.064 1.3036 LVSGPGTTLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.0313 0 10.4743 0 10.5684 0 9.04357 0 Q9ULJ1 ODF2L_HUMAN Protein BCAP (Basal body centriole-associated protein) (Outer dense fiber protein 2-like) (ODF2-like protein) ODF2L BCAP KIAA1229 Homo sapiens (Human) cell projection organization [GO:0030030]; negative regulation of cilium assembly [GO:1902018] centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737] 0.95869 -1.6981 LDHFTGAIEK 9.79627 10.7122 0 0 0 0 10.8587 0 0 9.93469 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9ULJ3 ZBT21_HUMAN Zinc finger and BTB domain-containing protein 21 (Zinc finger protein 295) ZBTB21 KIAA1227 ZNF295 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methyl-CpG binding [GO:0008327]; POZ domain binding [GO:0031208]" 0.9687 -3.3443 EASLWPCEK 0 0 0 0 0 0 0 0 0 0 0 9.52628 0 0 0 0 0 0 0 9.67025 0 0 0 0 0 0 0 Q9ULJ6 ZMIZ1_HUMAN Zinc finger MIZ domain-containing protein 1 (PIAS-like protein Zimp10) (Retinoic acid-induced protein 17) ZMIZ1 KIAA1224 RAI17 ZIMP10 Homo sapiens (Human) androgen receptor signaling pathway [GO:0030521]; artery morphogenesis [GO:0048844]; cellular senescence [GO:0090398]; developmental growth [GO:0048589]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of nucleic acid-templated transcription [GO:1903508]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein sumoylation [GO:0016925]; pyramidal neuron migration to cerebral cortex [GO:0021852]; regulation of protein sumoylation [GO:0033233]; regulation of transcription by RNA polymerase II [GO:0006357]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vasculogenesis [GO:0001570]; vitellogenesis [GO:0007296] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] nuclear receptor coactivator activity [GO:0030374]; SMAD binding [GO:0046332]; SUMO ligase activity [GO:0061665]; transcription coactivator activity [GO:0003713]; zinc ion binding [GO:0008270] 0.89817 -0.56604 DDPDGIPSK 0 0 0 8.57833 0 8.56201 0 0 0 10.8292 10.3261 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9ULJ7 ANR50_HUMAN Ankyrin repeat domain-containing protein 50 ANKRD50 KIAA1223 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] endosome [GO:0005768] 0.96832 -3.6315 AKQSNSSQPK 8.9377 0 11.1157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.58045 0 0 0 0 11.042 0 10.5495 Q9ULJ8 NEB1_HUMAN Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A) PPP1R9A KIAA1222 Homo sapiens (Human) actin filament organization [GO:0007015]; calcium-mediated signaling [GO:0019722]; modulation of chemical synaptic transmission [GO:0050804]; neuron projection development [GO:0031175] actin cytoskeleton [GO:0015629]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; filopodium [GO:0030175]; postsynaptic density [GO:0014069] actin filament binding [GO:0051015] 0.4183 0.6746 QNGTQVNNNNNIFERR 0 0 0 0 0 0 0 0 0 10.698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9ULK0 GRID1_HUMAN "Glutamate receptor ionotropic, delta-1 (GluD1) (GluR delta-1 subunit)" GRID1 KIAA1220 Homo sapiens (Human) "modulation of chemical synaptic transmission [GO:0050804]; regulation of postsynapse organization [GO:0099175]; social behavior [GO:0035176]; synaptic transmission, glutamatergic [GO:0035249]" extracellular exosome [GO:0070062]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839] glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315] 0.83279 0.19877 LEDRKWHSMASLNCIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1652 0 0 0 0 0 0 0 0 0 0 0 0 Q9ULK4 MED23_HUMAN Mediator of RNA polymerase II transcription subunit 23 (Activator-recruited cofactor 130 kDa component) (ARC130) (Cofactor required for Sp1 transcriptional activation subunit 3) (CRSP complex subunit 3) (Mediator complex subunit 23) (Protein sur-2 homolog) (hSur-2) (Transcriptional coactivator CRSP130) (Vitamin D3 receptor-interacting protein complex 130 kDa component) (DRIP130) MED23 ARC130 CRSP3 DRIP130 KIAA1216 SUR2 Homo sapiens (Human) positive regulation of gene expression [GO:0010628]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription initiation at RNA polymerase II promoter [GO:0006367] core mediator complex [GO:0070847]; mediator complex [GO:0016592]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] transcription coactivator activity [GO:0003713] 0.89158 -0.50873 GVRDLLKVILEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.62591 0 0 0 0 0 0 0 0 0 0 0 9.99944 Q9ULL0 K1210_HUMAN Acrosomal protein KIAA1210 KIAA1210 Homo sapiens (Human) acrosomal vesicle [GO:0001669] 0.9692 -3.5555 FEDEQEVFSESK 0 0 0 0 0 0 11.8665 0 13.6702 12.1177 11.9149 0 9.10127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9ULL1 PKHG1_HUMAN Pleckstrin homology domain-containing family G member 1 PLEKHG1 KIAA1209 Homo sapiens (Human) regulation of small GTPase mediated signal transduction [GO:0051056] cytosol [GO:0005829]; nucleoplasm [GO:0005654] guanyl-nucleotide exchange factor activity [GO:0005085]; small GTPase binding [GO:0031267] 0.95966 -1.822 AQWRVDSNGAPKTIADSATSPK 10.1329 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.2956 0 0 0 0 0 0 0 0 0 Q9ULL4 PLXB3_HUMAN Plexin-B3 PLXNB3 KIAA1206 PLXN6 Homo sapiens (Human) cell chemotaxis [GO:0060326]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell migration [GO:0030336]; negative regulation of GTPase activity [GO:0034260]; negative regulation of lamellipodium assembly [GO:0010593]; positive chemotaxis [GO:0050918]; positive regulation of axonogenesis [GO:0050772]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neuron projection development [GO:0010976]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287] cell surface [GO:0009986]; plasma membrane [GO:0005886]; semaphorin receptor complex [GO:0002116] cell-cell adhesion mediator activity [GO:0098632]; protein domain specific binding [GO:0019904]; Rho GDP-dissociation inhibitor binding [GO:0051022]; semaphorin receptor activity [GO:0017154] 0.92401 -1.0229 EEVRVHIGRGECLVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4044 0 0 0 0 0 0 0 0 0 0 Q9ULL5 PRR12_HUMAN Proline-rich protein 12 PRR12 KIAA1205 Homo sapiens (Human) neuron projection [GO:0043005]; nucleus [GO:0005634]; postsynaptic density [GO:0014069] 0.72576 0.35437 AGPSGATAGASGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2079 0 0 0 10.2244 0 0 0 0 0 0 0 Q9ULL8 SHRM4_HUMAN Protein Shroom4 (Second homolog of apical protein) SHROOM4 KIAA1202 SHAP Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; brain development [GO:0007420]; cognition [GO:0050890] actin filament [GO:0005884]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; stress fiber [GO:0001725] actin filament binding [GO:0051015]; myosin II binding [GO:0045159] 0.92163 -1.1316 AFPPPRPPPPNWEKYRLFR 0 0 0 8.50565 0 0 0 0 0 0 9.57703 0 0 0 0 0 0 0 0 0 0 9.61025 0 10.9055 0 0 9.37036 Q9ULM0 PKHH1_HUMAN Pleckstrin homology domain-containing family H member 1 (PH domain-containing family H member 1) PLEKHH1 KIAA1200 Homo sapiens (Human) cytoskeleton [GO:0005856] 0.92443 -0.99825 DLEHCLQGSVK 0 0 0 0 0 0 11.2973 0 0 0 10.1897 0 0 0 9.82115 0 0 0 0 0 0 0 0 0 8.42484 0 0 Q9ULM2 ZN490_HUMAN Zinc finger protein 490 ZNF490 KIAA1198 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.96799 -2.8828 DVMRATFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4952 0 0 0 0 0 Q9ULN7 PNM8B_HUMAN Paraneoplastic antigen-like protein 8B (PNMA-like protein 2) PNMA8B KIAA1183 PNMAL2 Homo sapiens (Human) 0.95301 -1.4833 AGEAKGQAPTGSK 0 0 0 0 0 0 0 0 11.2879 0 0 0 0 0 0 0 0 0 0 0 0 9.00725 0 0 0 0 0 Q9ULP9 TBC24_HUMAN TBC1 domain family member 24 TBC1D24 KIAA1171 Homo sapiens (Human) axon development [GO:0061564]; cellular response to oxidative stress [GO:0034599]; dendrite development [GO:0016358]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; neuron projection development [GO:0031175]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron migration [GO:2001224]; synaptic vesicle endocytosis [GO:0048488] cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; neuromuscular junction [GO:0031594]; plasma membrane [GO:0005886]; terminal bouton [GO:0043195] GTPase activator activity [GO:0005096] 0.96739 -2.9734 AGQPLESDSVK 0 0 12.3645 0 0 0 0 9.31399 0 0 0 0 0 0 0 0 9.79116 0 11 0 0 0 0 0 0 8.99557 0 Q9ULQ0 STRP2_HUMAN Striatin-interacting protein 2 (Protein FAM40B) STRIP2 FAM40B KIAA1170 Homo sapiens (Human) cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; regulation of cell shape [GO:0008360] cytoplasm [GO:0005737]; cytosol [GO:0005829] 0.96702 -2.3523 QDSLDIYNERDLFK 0 10.7055 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9ULR0 ISY1_HUMAN Pre-mRNA-splicing factor ISY1 homolog ISY1 KIAA1160 Homo sapiens (Human) "generation of catalytic spliceosome for second transesterification step [GO:0000350]; mRNA 3'-splice site recognition [GO:0000389]; mRNA splicing, via spliceosome [GO:0000398]" catalytic step 2 spliceosome [GO:0071013]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; post-mRNA release spliceosomal complex [GO:0071014]; post-spliceosomal complex [GO:0071020]; Prp19 complex [GO:0000974]; U2-type catalytic step 1 spliceosome [GO:0071006] RNA binding [GO:0003723] 0.96903 -4.2311 EVPGNRGYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.96175 0 0 0 0 0 0 Q9ULR3 PPM1H_HUMAN Protein phosphatase 1H (EC 3.1.3.16) PPM1H ARHCL1 KIAA1157 URCC2 Homo sapiens (Human) positive regulation of pyruvate dehydrogenase activity [GO:1904184]; protein dephosphorylation [GO:0006470] cytoplasm [GO:0005737]; glutamatergic synapse [GO:0098978]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] [pyruvate dehydrogenase (lipoamide)] phosphatase activity [GO:0004741]; identical protein binding [GO:0042802]; myosin phosphatase activity [GO:0017018]; phosphoprotein phosphatase activity [GO:0004721] 0.93974 -1.3074 AGAVTSTPNR 0 0 0 0 0 8.69418 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9ULS5 TMCC3_HUMAN Transmembrane and coiled-coil domain protein 3 TMCC3 KIAA1145 Homo sapiens (Human) endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789] 14-3-3 protein binding [GO:0071889]; identical protein binding [GO:0042802] 0.89035 -0.47753 LELHQQEQQALQTDTVNAK 0 0 0 0 10.0146 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2999 10.7366 10.448 0 0 Q9ULS6 KCNS2_HUMAN Potassium voltage-gated channel subfamily S member 2 (Delayed-rectifier K(+) channel alpha subunit 2) (Voltage-gated potassium channel subunit Kv9.2) KCNS2 KIAA1144 Homo sapiens (Human) potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of delayed rectifier potassium channel activity [GO:1902259] perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076] voltage-gated potassium channel activity [GO:0005249] 0.87157 0.062608 NPELFPYVLHFYHTGK 0 10.3349 0 0 0 0 10.2482 10.1664 10.2292 10.6251 0 10.2935 0 0 0 0 9.06153 0 0 0 0 0 0 0 0 0 0 Q9ULT0 TTC7A_HUMAN Tetratricopeptide repeat protein 7A (TPR repeat protein 7A) TTC7A KIAA1140 TTC7 Homo sapiens (Human) hemopoiesis [GO:0030097]; intracellular iron ion homeostasis [GO:0006879]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; protein localization to plasma membrane [GO:0072659] cytoplasm [GO:0005737]; plasma membrane [GO:0005886] 0.96407 -2.273 CRAEGHWDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.22846 0 0 0 0 0 0 0 10.605 Q9ULT6 ZNRF3_HUMAN E3 ubiquitin-protein ligase ZNRF3 (EC 2.3.2.27) (RING finger protein 203) (RING-type E3 ubiquitin transferase ZNRF3) (Zinc/RING finger protein 3) ZNRF3 KIAA1133 RNF203 Homo sapiens (Human) "limb development [GO:0060173]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein ubiquitination [GO:0016567]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; stem cell proliferation [GO:0072089]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt receptor catabolic process [GO:0038018]; Wnt signaling pathway [GO:0016055]" plasma membrane [GO:0005886] frizzled binding [GO:0005109]; metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] 0.89853 -0.66075 LMNIVNKQKVAR 0 0 0 0 0 9.82466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.92716 0 0 0 Q9ULT8 HECD1_HUMAN E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1) HECTD1 KIAA1131 Homo sapiens (Human) anatomical structure development [GO:0048856]; aorta development [GO:0035904]; heart valve development [GO:0003170]; natural killer cell differentiation [GO:0001779]; negative regulation of protein localization to plasma membrane [GO:1903077]; neural tube closure [GO:0001843]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein localization to plasma membrane [GO:0072659]; spongiotrophoblast differentiation [GO:0060708]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281] nuclear speck [GO:0016607] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630] 0.96753 -2.9 AVESMPR 0 0 0 0 0 0 0 10.5133 8.60203 0 0 0 0 0 0 0 9.26496 9.22783 0 0 10.3308 0 0 0 0 0 10.7178 Q9ULU4 ZMYD8_HUMAN MYND-type zinc finger-containing chromatin reader ZMYND8 (Cutaneous T-cell lymphoma-associated antigen se14-3) (CTCL-associated antigen se14-3) (Protein kinase C-binding protein 1) (Rack7) (Transcription coregulator ZMYND8) (Zinc finger MYND domain-containing protein 8) ZMYND8 KIAA1125 PRKCBP1 RACK7 Homo sapiens (Human) chromatin organization [GO:0006325]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of cell migration [GO:0030336]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; protein localization to chromatin [GO:0071168] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of DNA damage [GO:0090734] DNA-binding transcription factor binding [GO:0140297]; lysine-acetylated histone binding [GO:0070577]; methylated histone binding [GO:0035064]; protein domain specific binding [GO:0019904]; transcription corepressor activity [GO:0003714]; zinc ion binding [GO:0008270] 0.96362 -2.2399 EPKEPSPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.68314 0 0 0 0 0 0 0 0 Q9ULU8 CAPS1_HUMAN Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1) CADPS CAPS CAPS1 KIAA1121 Homo sapiens (Human) dense core granule exocytosis [GO:1990504]; exocytosis [GO:0006887]; positive regulation of exocytosis [GO:0045921]; protein transport [GO:0015031]; synaptic vesicle exocytosis [GO:0016079] cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; neuronal dense core vesicle membrane [GO:0099012]; presynapse [GO:0098793] lipid binding [GO:0008289]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901] 0.92275 -1.0565 LQMADQIAR 0 0 0 0 0 0 9.63147 0 0 0 9.29168 0 0 0 0 10.0771 0 10.2188 0 0 0 0 0 0 12.0158 0 0 Q9ULV0 MYO5B_HUMAN Unconventional myosin-Vb MYO5B KIAA1119 Homo sapiens (Human) actin filament organization [GO:0007015]; endosomal transport [GO:0016197]; protein transport [GO:0015031]; renal water homeostasis [GO:0003091]; vesicle transport along actin filament [GO:0030050]; vesicle-mediated transport [GO:0016192] actin cytoskeleton [GO:0015629]; apical cortex [GO:0045179]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; extracellular exosome [GO:0070062]; myosin complex [GO:0016459]; protein-containing complex [GO:0032991]; vesicle [GO:0031982] actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; microfilament motor activity [GO:0000146]; small GTPase binding [GO:0031267] 0.96949 -5.4768 IEARSAEHLK 0 0 0 0 0 0 0 0 8.52509 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.73044 0 0 Q9ULV8 CBLC_HUMAN E3 ubiquitin-protein ligase CBL-C (EC 2.3.2.27) (RING finger protein 57) (RING-type E3 ubiquitin transferase CBL-C) (SH3-binding protein CBL-3) (SH3-binding protein CBL-C) (Signal transduction protein CBL-C) CBLC CBL3 RNF57 Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of MAP kinase activity [GO:0043407]; protein ubiquitination [GO:0016567]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511] membrane raft [GO:0045121]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; epidermal growth factor receptor binding [GO:0005154]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.96229 -2.4736 DLLPRTAQLLR 0 0 0 0 0 0 0 0 0 0 0 0 0 8.70556 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9ULW0 TPX2_HUMAN Targeting protein for Xklp2 (Differentially expressed in cancerous and non-cancerous lung cells 2) (DIL-2) (Hepatocellular carcinoma-associated antigen 519) (Hepatocellular carcinoma-associated antigen 90) (Protein fls353) (Restricted expression proliferation-associated protein 100) (p100) TPX2 C20orf1 C20orf2 DIL2 HCA519 Homo sapiens (Human) activation of protein kinase activity [GO:0032147]; apoptotic process [GO:0006915]; cell division [GO:0051301]; microtubule nucleation [GO:0007020]; mitotic cell cycle [GO:0000278]; mitotic spindle assembly [GO:0090307]; negative regulation of microtubule depolymerization [GO:0007026]; regulation of mitotic spindle organization [GO:0060236] axon hillock [GO:0043203]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; mitotic spindle [GO:0072686]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819]; spindle pole [GO:0000922] importin-alpha family protein binding [GO:0061676]; protein kinase binding [GO:0019901] 0.95351 -1.495 ANLENKLLGK 0 0 0 0 0 0 0 9.61095 9.82707 12.0374 0 8.93517 0 0 0 0 0 0 0 0 0 0 10.047 0 0 0 0 Q9ULW2 FZD10_HUMAN Frizzled-10 (Fz-10) (hFz10) (FzE7) (CD antigen CD350) FZD10 Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; cellular response to retinoic acid [GO:0071300]; negative regulation of GTPase activity [GO:0034260]; neuron differentiation [GO:0030182]; non-canonical Wnt signaling pathway [GO:0035567]; non-canonical Wnt signaling pathway via JNK cascade [GO:0038031]; positive regulation of GTPase activity [GO:0043547]; positive regulation of JUN kinase activity [GO:0043507]; regulation of actin cytoskeleton organization [GO:0032956] cell surface [GO:0009986]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; Wnt receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147] 0.96601 -2.305 LNMDYWKILAAQHKCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6149 0 Q9ULW8 PADI3_HUMAN Protein-arginine deiminase type-3 (EC 3.5.3.15) (Peptidylarginine deiminase III) (Protein-arginine deiminase type III) PADI3 PAD3 PDI3 Homo sapiens (Human) cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654] calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein-arginine deiminase activity [GO:0004668] 0.96943 -3.0448 MSLQRIVR 8.66725 10.3545 10.3386 0 0 0 0 0 9.35074 0 0 0 0 0 0 0 0 0 0 11.5562 0 0 0 0 0 0 0 Q9ULX3 NOB1_HUMAN RNA-binding protein NOB1 (EC 3.1.-.-) (Phosphorylation regulatory protein HP-10) (Protein ART-4) NOB1 ART4 NOB1P PSMD8BP1 MSTP158 Homo sapiens (Human) cleavage involved in rRNA processing [GO:0000469]; maturation of SSU-rRNA [GO:0030490]; rRNA processing [GO:0006364]; visual perception [GO:0007601] "cytosol [GO:0005829]; nucleoplasm [GO:0005654]; preribosome, small subunit precursor [GO:0030688]" metal ion binding [GO:0046872]; RNA endonuclease activity [GO:0004521] 0.9607 -1.986 EVVTEIRDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9603 0 0 0 0 0 0 0 0 0 0 0 Q9ULX6 AKP8L_HUMAN A-kinase anchor protein 8-like (AKAP8-like protein) (Helicase A-binding protein 95) (HAP95) (Homologous to AKAP95 protein) (HA95) (Neighbor of A-kinase-anchoring protein 95) (Neighbor of AKAP95) AKAP8L NAKAP NAKAP95 HRIHFB2018 Homo sapiens (Human) cell cycle G2/M phase transition [GO:0044839]; mitotic chromosome condensation [GO:0007076]; mRNA processing [GO:0006397]; nuclear membrane disassembly [GO:0051081]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of mRNA export from nucleus [GO:0010793]; RNA splicing [GO:0008380] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; PML body [GO:0016605]; ribonucleoprotein complex [GO:1990904] DEAD/H-box RNA helicase binding [GO:0017151]; DNA binding [GO:0003677]; histone deacetylase binding [GO:0042826]; lamin binding [GO:0005521]; metal ion binding [GO:0046872]; protein kinase A regulatory subunit binding [GO:0034237]; RNA binding [GO:0003723] 0.9694 -6.5439 AVLSERDLYR 9.71158 0 0 0 0 0 0 0 9.00759 0 0 0 0 0 0 0 11.7413 0 0 0 0 0 0 0 0 0 0 Q9ULX9 MAFF_HUMAN Transcription factor MafF (U-Maf) (V-maf musculoaponeurotic fibrosarcoma oncogene homolog F) MAFF Homo sapiens (Human) in utero embryonic development [GO:0001701]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parturition [GO:0007567]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of epidermal cell differentiation [GO:0045604]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal muscle cell differentiation [GO:0035914] chromatin [GO:0000785]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.92178 -1.0991 EELQKQKSELER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3092 0 0 Q9ULY5 CLC4E_HUMAN C-type lectin domain family 4 member E (C-type lectin superfamily member 9) (Macrophage-inducible C-type lectin) (MINCLE) CLEC4E CLECSF9 MINCLE UNQ218/PRO244 Homo sapiens (Human) antifungal innate immune response [GO:0061760]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway [GO:0038094]; innate immune response [GO:0045087]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cytokine production [GO:0001819]; T cell differentiation involved in immune response [GO:0002292] cell projection [GO:0042995]; external side of plasma membrane [GO:0009897]; membrane [GO:0016020]; phagocytic cup [GO:0001891]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; glycolipid binding [GO:0051861]; pattern recognition receptor activity [GO:0038187] 0.90817 -0.73989 DSSNPRQNWNDVTCFLNYFR 9.68138 0 0 0 0 0 0 0 0 0 10.0983 10.1315 0 0 0 0 0 0 0 0 0 0 0 0 0 9.11116 0 Q9ULZ0 T53G3_HUMAN TP53-target gene 3 protein (TP53-inducible gene 3 protein) TP53TG3 TP53TG3A; TP53TG3B; TP53TG3C; TP53TG3D; TP53TG3E; TP53TG3F Homo sapiens (Human) cytoplasm [GO:0005737]; nucleus [GO:0005634] 0.95077 -1.4178 LVSPGNCDTLSPR 0 0 0 8.57833 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.64744 Q9ULZ2 STAP1_HUMAN Signal-transducing adaptor protein 1 (STAP-1) (BCR downstream-signaling protein 1) (Docking protein BRDG1) (Stem cell adaptor protein 1) STAP1 BRDG1 Homo sapiens (Human) "cellular response to lipopolysaccharide [GO:0071222]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of macrophage colony-stimulating factor signaling pathway [GO:1902227]; negative regulation of microglial cell migration [GO:1904140]; negative regulation of phosphorylation [GO:0042326]; negative regulation of ruffle assembly [GO:1900028]; positive regulation of B cell receptor signaling pathway [GO:0050861]; positive regulation of gene expression [GO:0010628]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of phagocytosis, engulfment [GO:0060100]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]" centriolar satellite [GO:0034451]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] macrophage colony-stimulating factor receptor binding [GO:0005157]; phospholipid binding [GO:0005543]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein tyrosine kinase activator activity [GO:0030296]; signaling adaptor activity [GO:0035591]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068] 0.91752 -0.87507 EYEHYWTELR 0 0 0 0 0 0 0 0 0 0 8.67243 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UM00 TMCO1_HUMAN Calcium load-activated calcium channel (CLAC channel) (GEL complex subunit TMCO1) (Transmembrane and coiled-coil domain-containing protein 1) (Transmembrane and coiled-coil domains protein 4) (Xenogeneic cross-immune protein PCIA3) TMCO1 TMCC4 PNAS-10 PNAS-136 UNQ151/PRO177 Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; ER overload response [GO:0006983]; multi-pass transmembrane protein insertion into ER membrane [GO:0160063] cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; multi-pass translocon complex [GO:0160064] calcium channel activity [GO:0005262]; ribosome binding [GO:0043022] 0.96118 -2.0036 ALSPWRVR 9.04067 12.8506 9.0802 11.61 11.6434 0 13.3146 13.2447 13.2 0 13.533 13.3483 10.5348 10.9753 10.9837 11.2204 0 11.3424 0 0 0 0 0 0 0 0 0 Q9UM07 PADI4_HUMAN Protein-arginine deiminase type-4 (EC 3.5.3.15) (HL-60 PAD) (Peptidylarginine deiminase IV) (Protein-arginine deiminase type IV) PADI4 PAD4 PADI5 PDI5 Homo sapiens (Human) chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; innate immune response [GO:0045087]; nucleosome assembly [GO:0006334]; post-translational protein modification [GO:0043687]; protein modification process [GO:0036211]; stem cell population maintenance [GO:0019827] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] calcium ion binding [GO:0005509]; histone arginine deiminase activity [GO:0140794]; histone H3R17 arginine deiminase activity [GO:0140797]; histone H3R2 arginine deiminase activity [GO:0140795]; histone H3R26 arginine deiminase activity [GO:0140798]; histone H3R8 arginine deiminase activity [GO:0140796]; identical protein binding [GO:0042802]; protein-arginine deiminase activity [GO:0004668] 0.95976 -1.9748 TLREHNSFVER 0 0 0 0 0 0 0 0 0 0 0 9.81481 0 0 0 0 0 0 0 9.84897 10.0225 0 0 0 0 10.1954 0 Q9UM11 FZR1_HUMAN Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1) FZR1 CDH1 FYR FZR KIAA1242 Homo sapiens (Human) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; DNA repair [GO:0006281]; lens fiber cell differentiation [GO:0070306]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of cellular senescence [GO:2000773]; positive regulation of anaphase-promoting complex-dependent catabolic process [GO:1905786]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein K11-linked ubiquitination [GO:0070979]; regulation of meiotic cell cycle [GO:0051445]; regulation of meiotic nuclear division [GO:0040020]; regulation of mitotic cell cycle [GO:0007346] anaphase-promoting complex [GO:0005680]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] anaphase-promoting complex binding [GO:0010997]; kinase inhibitor activity [GO:0019210]; ubiquitin ligase activator activity [GO:1990757]; ubiquitin ligase-substrate adaptor activity [GO:1990756] 0.8814 -0.31063 LQPSTPEKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3231 0 0 0 0 0 0 0 0 0 0 9.96996 0 Q9UM21 MGT4A_HUMAN "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVa) (GlcNAc-T IVa) (GnT-IVa) (N-acetylglucosaminyltransferase IVa) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVa) [Cleaved into: Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A soluble form]" MGAT4A Homo sapiens (Human) glyoxylate metabolic process [GO:0046487]; N-glycan processing [GO:0006491]; protein glycosylation [GO:0006486]; protein N-linked glycosylation [GO:0006487]; viral protein processing [GO:0019082] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; peroxisome [GO:0005777] "acetylglucosaminyltransferase activity [GO:0008375]; alanine-glyoxylate transaminase activity [GO:0008453]; alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity [GO:0008454]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]" 0.92141 -1.1388 DALNKFSDNTLK 0 0 0 0 0 0 0 0 8.37221 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UM47 NOTC3_HUMAN Neurogenic locus notch homolog protein 3 (Notch 3) [Cleaved into: Notch 3 extracellular truncation; Notch 3 intracellular domain] NOTCH3 Homo sapiens (Human) artery morphogenesis [GO:0048844]; axon guidance [GO:0007411]; forebrain development [GO:0030900]; glomerular capillary formation [GO:0072104]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuroblast differentiation [GO:0014016]; neuron fate commitment [GO:0048663]; Notch signaling pathway [GO:0007219]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944] actin cytoskeleton [GO:0015629]; cell surface [GO:0009986]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235] cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; signaling receptor activity [GO:0038023] 0.95904 -1.7716 AACQAKRGDQR 0 9.34081 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.1457 Q9UM54 MYO6_HUMAN Unconventional myosin-VI (Unconventional myosin-6) MYO6 KIAA0389 Homo sapiens (Human) "actin filament organization [GO:0007015]; actin filament-based movement [GO:0030048]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; endocytosis [GO:0006897]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear morphogenesis [GO:0042472]; intracellular protein transport [GO:0006886]; regulation of secretion [GO:0051046]; sensory perception of sound [GO:0007605]; vesicle transport along actin filament [GO:0030050]" actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; autophagosome [GO:0005776]; cell cortex [GO:0005938]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endocytic vesicle [GO:0030139]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; microvillus [GO:0005902]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; unconventional myosin complex [GO:0016461] actin binding [GO:0003779]; actin filament binding [GO:0051015]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; cytoskeletal motor activity [GO:0003774]; identical protein binding [GO:0042802]; minus-end directed microfilament motor activity [GO:0060001] 0.96861 -8.583 AEACIKMQK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.79765 0 8.77215 11.2321 0 0 0 0 0 0 0 10.4007 0 0 Q9UM73 ALK_HUMAN ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246) ALK Homo sapiens (Human) adult behavior [GO:0030534]; energy homeostasis [GO:0097009]; hippocampus development [GO:0021766]; negative regulation of lipid catabolic process [GO:0050995]; neuron development [GO:0048666]; peptidyl-tyrosine autophosphorylation [GO:0038083]; phosphorylation [GO:0016310]; positive regulation of dendrite development [GO:1900006]; positive regulation of kinase activity [GO:0033674]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein autophosphorylation [GO:0046777]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of dopamine receptor signaling pathway [GO:0060159]; regulation of neuron differentiation [GO:0045664]; response to environmental enrichment [GO:0090648]; signal transduction [GO:0007165]; swimming behavior [GO:0036269]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235] ATP binding [GO:0005524]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; NF-kappaB-inducing kinase activity [GO:0004704]; protein tyrosine kinase activity [GO:0004713]; receptor signaling protein tyrosine kinase activator activity [GO:0030298]; transmembrane receptor protein tyrosine kinase activity [GO:0004714] 0.95925 -1.837 DLLLPPSSSELK 0 0 0 0 10.6797 0 8.86468 10.3014 10.2904 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0382 0 Q9UM82 SPAT2_HUMAN Spermatogenesis-associated protein 2 SPATA2 KIAA0757 PD1 Homo sapiens (Human) necroptotic process [GO:0070266]; protein K63-linked deubiquitination [GO:0070536]; protein linear deubiquitination [GO:1990108]; regulation of inflammatory response [GO:0050727]; regulation of necroptotic process [GO:0060544]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; seminiferous tubule development [GO:0072520]; spermatogenesis [GO:0007283] cytoplasm [GO:0005737]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654] protein-containing complex binding [GO:0044877]; signaling receptor complex adaptor activity [GO:0030159]; ubiquitin-specific protease binding [GO:1990381] 0.82212 0.21804 SVDAYDSYWESR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.26108 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UMD9 COHA1_HUMAN Collagen alpha-1(XVII) chain (180 kDa bullous pemphigoid antigen 2) (Bullous pemphigoid antigen 2) [Cleaved into: 120 kDa linear IgA disease antigen (120 kDa linear IgA dermatosis antigen) (Linear IgA disease antigen 1) (LAD-1); 97 kDa linear IgA disease antigen (97 kDa linear IgA bullous dermatosis antigen) (97 kDa LAD antigen) (97-LAD) (Linear IgA bullous disease antigen of 97 kDa) (LABD97)] COL17A1 BP180 BPAG2 Homo sapiens (Human) cell-matrix adhesion [GO:0007160]; epidermis development [GO:0008544]; extracellular matrix organization [GO:0030198]; hemidesmosome assembly [GO:0031581] basement membrane [GO:0005604]; cell-cell junction [GO:0005911]; collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; hemidesmosome [GO:0030056]; plasma membrane [GO:0005886] extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020] 0.51604 0.59513 VFTASPASIAATSFSEDTLKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1348 0 0 Q9UMF0 ICAM5_HUMAN Intercellular adhesion molecule 5 (ICAM-5) (Telencephalin) ICAM5 TLCN TLN Homo sapiens (Human) cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; phagocytosis [GO:0006909]; regulation of synapse assembly [GO:0051963] glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886] integrin binding [GO:0005178] 0.84708 0.15401 ALSGTYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0331 0 0 0 0 0 0 Q9UMN6 KMT2B_HUMAN Histone-lysine N-methyltransferase 2B (Lysine N-methyltransferase 2B) (EC 2.1.1.364) (Myeloid/lymphoid or mixed-lineage leukemia protein 4) (Trithorax homolog 2) (WW domain-binding protein 7) (WBP-7) KMT2B HRX2 KIAA0304 MLL2 MLL4 TRX2 WBP7 Homo sapiens (Human) histone H3-K4 methylation [GO:0051568]; positive regulation of DNA-templated transcription [GO:0045893] histone methyltransferase complex [GO:0035097]; MLL1/2 complex [GO:0044665]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] histone H3K4 methyltransferase activity [GO:0042800]; histone H3K4 monomethyltransferase activity [GO:0140945]; histone H3K4 trimethyltransferase activity [GO:0140999]; unmethylated CpG binding [GO:0045322]; zinc ion binding [GO:0008270] 0.97008 -4.3264 CDKIEARK 9.32879 0 0 0 0 0 0 0 9.11543 0 0 0 0 0 0 0 0 0 0 0 8.69624 0 0 11.8337 0 0 0 Q9UMR3 TBX20_HUMAN T-box transcription factor TBX20 (T-box protein 20) TBX20 Homo sapiens (Human) aortic valve morphogenesis [GO:0003180]; atrial septum morphogenesis [GO:0060413]; atrioventricular canal development [GO:0036302]; atrioventricular valve development [GO:0003171]; blood circulation [GO:0008015]; branching involved in blood vessel morphogenesis [GO:0001569]; cardiac chamber formation [GO:0003207]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right ventricle morphogenesis [GO:0003215]; cardiac septum development [GO:0003279]; cell fate specification [GO:0001708]; cell population proliferation [GO:0008283]; dorsal/ventral pattern formation [GO:0009953]; embryonic heart tube elongation [GO:0036306]; embryonic heart tube morphogenesis [GO:0003143]; endocardial cushion formation [GO:0003272]; endocardial cushion morphogenesis [GO:0003203]; endoderm formation [GO:0001706]; foramen ovale closure [GO:0035922]; heart looping [GO:0001947]; lateral mesoderm formation [GO:0048370]; mesenchymal cell development [GO:0014031]; motor neuron migration [GO:0097475]; muscle contraction [GO:0006936]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of SMAD protein complex assembly [GO:0010991]; negative regulation of transcription by RNA polymerase II [GO:0000122]; outflow tract septum morphogenesis [GO:0003148]; pericardium morphogenesis [GO:0003344]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; pulmonary valve formation [GO:0003193]; pulmonary vein morphogenesis [GO:0060577]; regulation of transcription by RNA polymerase II [GO:0006357]; tricuspid valve development [GO:0003175]; vasculogenesis [GO:0001570]; visceral motor neuron differentiation [GO:0021524] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.65377 0.39554 IACSLETK 0 0 0 0 0 0 9.65928 0 9.59528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UMS4 PRP19_HUMAN Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Nuclear matrix protein 200) (PRP19/PSO4 homolog) (hPso4) (RING-type E3 ubiquitin transferase PRP19) (Senescence evasion factor) PRPF19 NMP200 PRP19 SNEV Homo sapiens (Human) "DNA damage checkpoint signaling [GO:0000077]; double-strand break repair via nonhomologous end joining [GO:0006303]; lipid biosynthetic process [GO:0008610]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of neuron differentiation [GO:0045666]; proteasomal protein catabolic process [GO:0010498]; protein K63-linked ubiquitination [GO:0070534]; protein localization [GO:0008104]; protein polyubiquitination [GO:0000209]; spliceosomal complex assembly [GO:0000245]; spliceosomal tri-snRNP complex assembly [GO:0000244]" catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; lipid droplet [GO:0005811]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Prp19 complex [GO:0000974]; site of double-strand break [GO:0035861]; spindle [GO:0005819]; spliceosomal complex [GO:0005681]; U2-type catalytic step 1 spliceosome [GO:0071006]; U2-type catalytic step 2 spliceosome [GO:0071007] identical protein binding [GO:0042802]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; ubiquitin-ubiquitin ligase activity [GO:0034450] 0.84383 0.15298 TVPEELVKPEELSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.89798 0 0 0 0 0 0 Q9UMS6 SYNP2_HUMAN Synaptopodin-2 (Genethonin-2) (Myopodin) SYNPO2 Homo sapiens (Human) autophagosome assembly [GO:0000045]; chaperone-mediated autophagy [GO:0061684]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of cell migration [GO:0030335]; regulation of Rho-dependent protein serine/threonine kinase activity [GO:2000298] actin cytoskeleton [GO:0015629]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; stress fiber [GO:0001725]; vesicle tethering complex [GO:0099023]; Z disc [GO:0030018] 14-3-3 protein binding [GO:0071889]; actin binding [GO:0003779]; alpha-actinin binding [GO:0051393]; filamin binding [GO:0031005]; muscle alpha-actinin binding [GO:0051371]; protein-macromolecule adaptor activity [GO:0030674] 0.81255 0.22212 SPDPDPNLSHDR 0 0 0 0 0 0 0 0 0 10.262 10.0275 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UMX1 SUFU_HUMAN Suppressor of fused homolog (SUFUH) SUFU UNQ650/PRO1280 Homo sapiens (Human) aorta development [GO:0035904]; coronary vasculature development [GO:0060976]; cytoplasmic sequestering of transcription factor [GO:0042994]; heart looping [GO:0001947]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of hh target transcription factor activity [GO:1990787]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein import into nucleus [GO:0042308]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; neural tube closure [GO:0001843]; regulation of DNA-templated transcription [GO:0006355]; signal transduction [GO:0007165]; skin development [GO:0043588]; smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831]; smoothened signaling pathway involved in spinal cord motor neuron cell fate specification [GO:0021776]; smoothened signaling pathway involved in ventral spinal cord interneuron specification [GO:0021775]; ventricular septum development [GO:0003281] ciliary base [GO:0097546]; ciliary tip [GO:0097542]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; GLI-SUFU complex [GO:1990788]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] beta-catenin binding [GO:0008013]; protein kinase binding [GO:0019901]; transcription corepressor activity [GO:0003714] 0.96508 -2.378 EYSWPEKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2016 0 0 0 0 0 0 0 0 Q9UMX2 OAZ3_HUMAN Ornithine decarboxylase antizyme 3 (AZ3) (ODC-Az 3) OAZ3 Homo sapiens (Human) negative regulation of polyamine transmembrane transport [GO:1902268]; polyamine biosynthetic process [GO:0006596]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of protein catabolic process [GO:0045732]; spermatogenesis [GO:0007283] blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ornithine decarboxylase inhibitor activity [GO:0008073] 0.77108 0.26973 ESLTATLEYVEEKTNVDSVFVNFQNDRNDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6096 Q9UMX6 GUC1B_HUMAN Guanylyl cyclase-activating protein 2 (GCAP 2) (Guanylate cyclase activator 1B) GUCA1B GCAP2 Homo sapiens (Human) body fluid secretion [GO:0007589]; cell-cell signaling [GO:0007267]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of guanylate cyclase activity [GO:0031282]; visual perception [GO:0007601] cone photoreceptor outer segment [GO:0120199]; photoreceptor disc membrane [GO:0097381]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; calcium sensitive guanylate cyclase activator activity [GO:0008048] 0.9073 -0.73561 IYDKDGNGCIDR 0 0 0 0 0 0 0 0 10.3137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UMX9 S45A2_HUMAN Membrane-associated transporter protein (Melanoma antigen AIM1) (Protein AIM-1) (Solute carrier family 45 member 2) SLC45A2 AIM1 MATP Homo sapiens (Human) developmental pigmentation [GO:0048066]; lysosomal lumen pH elevation [GO:0035752]; melanin biosynthetic process from tyrosine [GO:0006583]; response to stimulus [GO:0050896]; sucrose transport [GO:0015770]; visual perception [GO:0007601] melanosome membrane [GO:0033162]; membrane [GO:0016020] glucose:proton symporter activity [GO:0005356]; sucrose:proton symporter activity [GO:0008506] 0.90779 -0.73915 VKNGYVNPELAMQGAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.6295 0 0 0 0 0 0 0 0 0 0 0 0 Q9UMY1 NOL7_HUMAN Nucleolar protein 7 (Nucleolar protein of 27 kDa) NOL7 C6orf90 NOP27 Homo sapiens (Human) ribosomal small subunit biogenesis [GO:0042274] chromosome [GO:0005694]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; small-subunit processome [GO:0032040] RNA binding [GO:0003723] 0.96905 -3.3761 MVQLRPR 0 0 9.52025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UMZ2 SYNRG_HUMAN Synergin gamma (AP1 subunit gamma-binding protein 1) (Gamma-synergin) SYNRG AP1GBP1 SYNG Homo sapiens (Human) endocytosis [GO:0006897]; intracellular protein transport [GO:0006886] AP-1 adaptor complex [GO:0030121]; clathrin coat of trans-Golgi network vesicle [GO:0030130]; cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; perinuclear region of cytoplasm [GO:0048471] 0.88251 -0.075842 ALPSMDK 10.0806 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.4816 0 0 10.0425 0 0 0 0 0 0 10.454 11.0832 Q9UMZ3 PTPRQ_HUMAN Phosphatidylinositol phosphatase PTPRQ (EC 3.1.3.-) (Receptor-type tyrosine-protein phosphatase Q) (PTP-RQ) (R-PTP-Q) (EC 3.1.3.48) PTPRQ Homo sapiens (Human) peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; regulation of fat cell differentiation [GO:0045598] membrane [GO:0016020]; receptor complex [GO:0043235] protein tyrosine phosphatase activity [GO:0004725] 0.40899 0.69331 ITPSTEK 0 11.1243 0 0 0 0 0 0 0 0 11.4408 0 0 0 0 10.609 0 0 0 0 0 0 0 0 0 0 0 Q9UN66 PCDB8_HUMAN Protocadherin beta-8 (PCDH-beta-8) (Protocadherin-3I) PCDHB8 PCDH3I Homo sapiens (Human) cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399] plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; identical protein binding [GO:0042802] 0.88458 -0.19042 DLGLEQREFSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.90543 0 0 0 Q9UN70 PCDGK_HUMAN Protocadherin gamma-C3 (PCDH-gamma-C3) (Protocadherin-2) (Protocadherin-43) (PC-43) PCDHGC3 PCDH2 Homo sapiens (Human) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; synapse organization [GO:0050808] membrane [GO:0016020]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.96447 -2.4321 APAGGNGNK 0 0 0 0 0 0 0 0 0 0 9.56041 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.58188 Q9UN71 PCDGG_HUMAN Protocadherin gamma-B4 (PCDH-gamma-B4) (Cadherin-20) (Fibroblast cadherin-2) PCDHGB4 CDH20 FIB2 Homo sapiens (Human) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399] membrane [GO:0016020]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.8477 0.16903 APAGGNGNK 0 0 0 0 0 0 0 9.21478 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UN74 PCDA4_HUMAN Protocadherin alpha-4 (PCDH-alpha-4) PCDHA4 Homo sapiens (Human) cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399] plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; identical protein binding [GO:0042802] 0.96383 -2.4081 ALDETDAPRHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.5982 0 0 0 0 0 0 0 0 0 0 0 Q9UN75 PCDAC_HUMAN Protocadherin alpha-12 (PCDH-alpha-12) PCDHA12 Homo sapiens (Human) cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399] plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.95936 -1.9186 DINDNPPVFREREQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.0961 0 0 0 0 0 0 0 0 0 Q9UN79 SOX13_HUMAN Transcription factor SOX-13 (Islet cell antigen 12) (SRY (Sex determining region Y)-box 13) (Type 1 diabetes autoantigen ICA12) SOX13 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; cell fate commitment [GO:0045165]; gamma-delta T cell differentiation [GO:0042492]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of gamma-delta T cell differentiation [GO:0045588]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; spinal cord oligodendrocyte cell differentiation [GO:0021529] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity [GO:0001217]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription cis-regulatory region binding [GO:0000976]" 0.88365 -0.32678 EEGEGTDDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7661 0 0 0 0 0 0 Q9UN81 LORF1_HUMAN LINE-1 retrotransposable element ORF1 protein (L1ORF1p) (LINE retrotransposable element 1) (LINE1 retrotransposable element 1) L1RE1 LRE1 Homo sapiens (Human) retrotransposition [GO:0032197] cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; nucleolus [GO:0005730]; ribonucleoprotein complex [GO:1990904] identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727] 0.91441 -0.78821 VSAMEDEMNEMKR 0 0 0 0 0 0 0 0 0 8.96099 8.90123 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UN86 G3BP2_HUMAN Ras GTPase-activating protein-binding protein 2 (G3BP-2) (GAP SH3 domain-binding protein 2) G3BP2 KIAA0660 Homo sapiens (Human) cytoplasmic sequestering of NF-kappaB [GO:0007253]; innate immune response [GO:0045087]; mRNA transport [GO:0051028]; positive regulation of stress granule assembly [GO:0062029]; protein homooligomerization [GO:0051260]; Ras protein signal transduction [GO:0007265]; stress granule assembly [GO:0034063] cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904] molecular condensate scaffold activity [GO:0140693]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; signaling receptor complex adaptor activity [GO:0030159] 0.91425 -0.82529 TEELKPQVEEKNLEELEEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.36931 0 0 0 Q9UNA0 ATS5_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAM-TS 5) (ADAM-TS5) (ADAMTS-5) (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 11) (ADAM-TS 11) (ADAMTS-11) (ADMP-2) (Aggrecanase-2) ADAMTS5 ADAMTS11 ADMP2 Homo sapiens (Human) aortic valve morphogenesis [GO:0003180]; defense response to bacterium [GO:0042742]; endocardial cushion morphogenesis [GO:0003203]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; myoblast fusion [GO:0007520]; negative regulation of cold-induced thermogenesis [GO:0120163]; proteolysis [GO:0006508]; pulmonary valve morphogenesis [GO:0003184]; tooth eruption [GO:0044691] collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615] endopeptidase activity [GO:0004175]; extracellular matrix binding [GO:0050840]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; peptidase activity [GO:0008233]; zinc ion binding [GO:0008270] 0.9228 -1.0579 HEQCEAKNGYQSDAK 9.23644 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.15142 0 0 0 0 0 Q9UNA1 RHG26_HUMAN Rho GTPase-activating protein 26 (GTPase regulator associated with focal adhesion kinase) (Oligophrenin-1-like protein) (Rho-type GTPase-activating protein 26) ARHGAP26 GRAF KIAA0621 OPHN1L Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; nervous system development [GO:0007399]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925] GTPase activator activity [GO:0005096]; phospholipid binding [GO:0005543] 0.86995 0.053657 ESQLQEADSQVDLVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.7541 0 0 0 0 0 0 0 0 0 0 Q9UNA4 POLI_HUMAN DNA polymerase iota (EC 2.7.7.7) (Eta2) (RAD30 homolog B) POLI RAD30B Homo sapiens (Human) DNA repair [GO:0006281]; DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985] cytoplasmic ribonucleoprotein granule [GO:0036464]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654] damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872] 0.89228 -0.51107 AGSDFHIGHK 0 0 0 0 0 0 0 0 0 0 0 10.8669 9.39002 0 0 0 0 9.5283 0 0 0 0 0 0 0 0 0 Q9UNE0 EDAR_HUMAN Tumor necrosis factor receptor superfamily member EDAR (Anhidrotic ectodysplasin receptor 1) (Downless homolog) (EDA-A1 receptor) (Ectodermal dysplasia receptor) (Ectodysplasin-A receptor) EDAR DL Homo sapiens (Human) apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; epidermis development [GO:0008544]; hair follicle development [GO:0001942]; odontogenesis of dentin-containing tooth [GO:0042475]; pigmentation [GO:0043473]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of JNK cascade [GO:0046330]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; salivary gland cavitation [GO:0060662] apical part of cell [GO:0045177]; membrane [GO:0016020]; plasma membrane [GO:0005886] signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888] 0.9148 -0.80409 GGYQICRR 0 0 0 0 0 0 0 0 0 10.7138 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UNE2 RPH3L_HUMAN Rab effector Noc2 (No C2 domains protein) (Rabphilin-3A-like protein) RPH3AL NOC2 Homo sapiens (Human) exocytosis [GO:0006887]; G protein-coupled receptor signaling pathway [GO:0007186]; glucose homeostasis [GO:0042593]; intracellular protein transport [GO:0006886]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; positive regulation of insulin secretion [GO:0032024]; regulation of calcium ion-dependent exocytosis [GO:0017158]; spontaneous neurotransmitter secretion [GO:0061669] cytoplasm [GO:0005737]; presynapse [GO:0098793]; synapse [GO:0045202]; transport vesicle membrane [GO:0030658] cytoskeletal protein binding [GO:0008092]; metal ion binding [GO:0046872]; small GTPase binding [GO:0031267] 0.96183 -2.5603 LPSTGVR 0 0 0 0 0 0 0 0 0 0 8.92825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UNF0 PACN2_HUMAN Protein kinase C and casein kinase substrate in neurons protein 2 (Syndapin-2) (Syndapin-II) (SdpII) PACSIN2 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; caveola assembly [GO:0070836]; caveolin-mediated endocytosis [GO:0072584]; cell projection morphogenesis [GO:0048858]; cytoskeleton organization [GO:0007010]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of endocytosis [GO:0045806]; plasma membrane tubulation [GO:0097320]; protein localization to endosome [GO:0036010]; regulation of endocytosis [GO:0030100] caveola [GO:0005901]; cell-cell junction [GO:0005911]; centriolar satellite [GO:0034451]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; ruffle membrane [GO:0032587] cadherin binding [GO:0045296]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; phosphatidic acid binding [GO:0070300]; phospholipid binding [GO:0005543] 0.87034 0.056003 AGDELTK 11.2667 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.85134 0 0 0 Q9UNF1 MAGD2_HUMAN Melanoma-associated antigen D2 (11B6) (Breast cancer-associated gene 1 protein) (BCG-1) (Hepatocellular carcinoma-associated protein JCL-1) (MAGE-D2 antigen) MAGED2 BCG1 Homo sapiens (Human) female pregnancy [GO:0007565]; negative regulation of transcription by RNA polymerase II [GO:0000122]; renal sodium ion absorption [GO:0070294] cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093] 0 5.2129 AGYSLEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.27738 0 0 0 0 Q9UNH5 CC14A_HUMAN Dual specificity protein phosphatase CDC14A (EC 3.1.3.16) (EC 3.1.3.48) (CDC14 cell division cycle 14 homolog A) CDC14A Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; cilium assembly [GO:0060271]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of cytokinesis [GO:0032467]; protein dephosphorylation [GO:0006470]; regulation of exit from mitosis [GO:0007096]; sensory perception of sound [GO:0007605] centrosome [GO:0005813]; cytosol [GO:0005829]; kinociliary basal body [GO:1902636]; kinocilium [GO:0060091]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; spindle pole [GO:0000922]; stereocilium tip [GO:0032426] myosin phosphatase activity [GO:0017018]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138] 0.92125 -1.1062 IVHYTCFDQR 0 0 0 0 11.0098 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1954 0 0 0 0 0 0 0 Q9UNI1 CELA1_HUMAN Chymotrypsin-like elastase family member 1 (EC 3.4.21.36) (Elastase-1) (Pancreatic elastase 1) CELA1 ELA1 Homo sapiens (Human) elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; transcription by RNA polymerase II [GO:0006366]; Wnt signaling pathway [GO:0016055] extracellular space [GO:0005615] metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252] 0.72145 0.36379 VVGGTEAGR 0 0 0 0 0 0 0 0 0 0 9.08138 9.13766 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UNN4 TF2AY_HUMAN "TFIIA-alpha and beta-like factor (General transcription factor II A, 1-like factor)" GTF2A1L ALF GTF2A1LF Homo sapiens (Human) cognition [GO:0050890]; transcription by RNA polymerase II [GO:0006366]; transcription initiation at RNA polymerase II promoter [GO:0006367] cytoplasm [GO:0005737]; male germ cell nucleus [GO:0001673]; transcription factor TFIIA complex [GO:0005672] DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713] 0.95824 -1.6725 DLKQLWETK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.5428 0 0 0 9.5509 0 Q9UNP9 PPIE_HUMAN Peptidyl-prolyl cis-trans isomerase E (PPIase E) (EC 5.2.1.8) (Cyclophilin E) (Cyclophilin-33) (Rotamase E) PPIE CYP33 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; regulation of DNA-templated transcription [GO:0006355]" catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; U2-type catalytic step 2 spliceosome [GO:0071007] cyclosporin A binding [GO:0016018]; mRNA binding [GO:0003729]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723] 0.61336 0.4257 QIEAQGSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.83988 0 0 0 0 0 0 0 0 0 0 0 Q9UNQ0 ABCG2_HUMAN Broad substrate specificity ATP-binding cassette transporter ABCG2 (EC 7.6.2.2) (ATP-binding cassette sub-family G member 2) (Breast cancer resistance protein) (CDw338) (Mitoxantrone resistance-associated protein) (Placenta-specific ATP-binding cassette transporter) (Urate exporter) (CD antigen CD338) ABCG2 ABCP BCRP BCRP1 MXR Homo sapiens (Human) biotin transport [GO:0015878]; cellular detoxification [GO:1990748]; export across plasma membrane [GO:0140115]; lipid transport [GO:0006869]; organic anion transport [GO:0015711]; renal urate salt excretion [GO:0097744]; riboflavin transport [GO:0032218]; transepithelial transport [GO:0070633]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate metabolic process [GO:0046415]; xenobiotic transport across blood-brain barrier [GO:1990962] apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; external side of apical plasma membrane [GO:0098591]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] ABC-type xenobiotic transporter activity [GO:0008559]; ATP binding [GO:0005524]; ATPase-coupled transmembrane transporter activity [GO:0042626]; biotin transmembrane transporter activity [GO:0015225]; efflux transmembrane transporter activity [GO:0015562]; identical protein binding [GO:0042802]; organic anion transmembrane transporter activity [GO:0008514]; protein homodimerization activity [GO:0042803]; riboflavin transmembrane transporter activity [GO:0032217]; urate transmembrane transporter activity [GO:0015143]; xenobiotic transmembrane transporter activity [GO:0042910] 0.58706 0.4673 LLSDLLPMR 8.649 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2149 0 Q9UNQ2 DIM1_HUMAN "Probable dimethyladenosine transferase (EC 2.1.1.183) (DIM1 dimethyladenosine transferase 1 homolog) (DIM1 dimethyladenosine transferase 1-like) (Probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase) (Probable 18S rRNA dimethylase) (Probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase)" DIMT1 DIMT1L HUSSY-05 Homo sapiens (Human) positive regulation of rRNA processing [GO:2000234]; ribosomal small subunit biogenesis [GO:0042274]; rRNA methylation [GO:0031167] cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040] "18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity [GO:0052909]; RNA binding [GO:0003723]; rRNA (adenine-N6,N6-)-dimethyltransferase activity [GO:0000179]" 0.89619 -0.54062 ITFVRKNK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.13042 0 0 8.75796 0 0 0 0 0 0 0 0 0 0 Q9UNS1 TIM_HUMAN Protein timeless homolog (hTIM) TIMELESS TIM TIM1 TIMELESS1 Homo sapiens (Human) branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle phase transition [GO:0044770]; cell division [GO:0051301]; cellular response to bleomycin [GO:1904976]; cellular response to cisplatin [GO:0072719]; cellular response to hydroxyurea [GO:0072711]; circadian rhythm [GO:0007623]; detection of abiotic stimulus [GO:0009582]; DNA damage response [GO:0006974]; DNA repair [GO:0006281]; DNA replication checkpoint signaling [GO:0000076]; lung development [GO:0030324]; morphogenesis of an epithelium [GO:0002009]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; regulation of circadian rhythm [GO:0042752]; replication fork arrest [GO:0043111] chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; replication fork protection complex [GO:0031298]; site of double-strand break [GO:0035861] DNA binding [GO:0003677]; identical protein binding [GO:0042802] 0.43069 0.65996 EAFASEK 0 0 0 9.17812 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UNS2 CSN3_HUMAN COP9 signalosome complex subunit 3 (SGN3) (Signalosome subunit 3) (JAB1-containing signalosome subunit 3) COPS3 CSN3 Homo sapiens (Human) "in utero embryonic development [GO:0001701]; protein deneddylation [GO:0000338]; protein neddylation [GO:0045116]; regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:1902162]; regulation of protein neddylation [GO:2000434]; response to light stimulus [GO:0009416]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511]" COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] 0.80043 0.23924 VQLSGPQEAEK 0 0 0 0 0 10.1669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UNU6 CP8B1_HUMAN 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase (EC 1.14.14.139) (7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase) (CYPVIIIB1) (Cytochrome P450 8B1) (Sterol 12-alpha-hydroxylase) CYP8B1 CYP12 Homo sapiens (Human) bile acid biosynthetic process [GO:0006699]; bile acid signaling pathway [GO:0038183]; positive regulation of intestinal cholesterol absorption [GO:0045797]; response to cholesterol [GO:0070723]; response to nutrient levels [GO:0031667]; sterol metabolic process [GO:0016125] endoplasmic reticulum membrane [GO:0005789] "5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase activity [GO:0033779]; 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity [GO:0033778]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; sterol 12-alpha-hydroxylase activity [GO:0008397]" 0.87395 0.036163 LETKQSFAFK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.6339 9.77207 0 0 0 Q9UNW8 GP132_HUMAN Probable G-protein coupled receptor 132 (G2 accumulation protein) GPR132 G2A Homo sapiens (Human) G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930] 0.85078 0.15905 ETCFDMLQMDSR 0 0 0 0 0 0 8.43659 0 0 0 8.79824 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UNW9 NOVA2_HUMAN RNA-binding protein Nova-2 (Astrocytic NOVA1-like RNA-binding protein) (Neuro-oncological ventral antigen 2) NOVA2 ANOVA NOVA3 Homo sapiens (Human) "central nervous system neuron development [GO:0021954]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of cold-induced thermogenesis [GO:0120163]; neuron differentiation [GO:0030182]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of axon guidance [GO:1902667]; regulation of RNA metabolic process [GO:0051252]" cytoplasm [GO:0005737]; nucleus [GO:0005634] mRNA binding [GO:0003729]; RNA binding [GO:0003723]; sequence-specific mRNA binding [GO:1990825] 0.82871 0.20503 VTYEQGVR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.02223 0 0 0 0 0 0 Q9UNX4 WDR3_HUMAN WD repeat-containing protein 3 WDR3 Homo sapiens (Human) maturation of SSU-rRNA [GO:0030490]; ribosomal small subunit biogenesis [GO:0042274] nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; Pwp2p-containing subcomplex of 90S preribosome [GO:0034388]; small-subunit processome [GO:0032040] RNA binding [GO:0003723]; snoRNA binding [GO:0030515] 0.95043 -1.4065 GIKSSELEESLLVLPFSYVPDILK 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2908 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UNY4 TTF2_HUMAN Transcription termination factor 2 (EC 3.6.4.-) (Lodestar homolog) (RNA polymerase II termination factor) (Transcription release factor 2) (F2) (HuF2) TTF2 Homo sapiens (Human) DNA repair [GO:0006281]; DNA-templated transcription termination [GO:0006353]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380]; termination of RNA polymerase II transcription [GO:0006369] cytosol [GO:0005829]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; transcription elongation factor complex [GO:0008023] "ATP binding [GO:0005524]; ATP-dependent activity, acting on DNA [GO:0008094]; ATP-dependent chromatin remodeler activity [GO:0140658]; DNA binding [GO:0003677]; helicase activity [GO:0004386]; hydrolase activity [GO:0016787]; zinc ion binding [GO:0008270]" 0.88825 -0.39923 DLSSGLVPK 15.648 15.4871 15.4233 13.2587 13.4602 13.4497 14.9258 15.1523 15.1956 15.5627 15.1781 15.3134 14.1555 14.0697 14.1699 14.9726 15.0677 14.7965 11.7158 0 11.7677 0 11.299 11.3718 10.6994 12.0431 0 Q9UNZ2 NSF1C_HUMAN NSFL1 cofactor p47 (UBX domain-containing protein 2C) (p97 cofactor p47) NSFL1C UBXN2C Homo sapiens (Human) autophagosome assembly [GO:0000045]; establishment of mitotic spindle orientation [GO:0000132]; Golgi organization [GO:0007030]; membrane fusion [GO:0061025]; negative regulation of protein localization to centrosome [GO:1904780]; nuclear membrane reassembly [GO:0031468]; positive regulation of mitotic centrosome separation [GO:0046604]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi stack [GO:0005795]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; VCP-NSFL1C complex [GO:1990730] lipid binding [GO:0008289]; ubiquitin binding [GO:0043130] 0.77129 0.26734 ELADESQTLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2527 0 10.3184 Q9UP38 FZD1_HUMAN Frizzled-1 (Fz-1) (hFz1) (FzE1) FZD1 Homo sapiens (Human) astrocyte-dopaminergic neuron signaling [GO:0036520]; autocrine signaling [GO:0035425]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation [GO:0044338]; canonical Wnt signaling pathway involved in osteoblast differentiation [GO:0044339]; cell-cell signaling [GO:0007267]; endothelial cell differentiation [GO:0045446]; hard palate development [GO:0060022]; membranous septum morphogenesis [GO:0003149]; muscular septum morphogenesis [GO:0003150]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; neuron differentiation [GO:0030182]; non-canonical Wnt signaling pathway [GO:0035567]; outflow tract morphogenesis [GO:0003151]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein phosphorylation [GO:0001934]; presynapse assembly [GO:0099054]; regulation of presynapse assembly [GO:1905606]; response to xenobiotic stimulus [GO:0009410]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953] cell surface [GO:0009986]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; Wnt signalosome [GO:1990909] frizzled binding [GO:0005109]; G protein-coupled receptor activity [GO:0004930]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; Wnt receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147] 0.82896 0.20959 TLNSWRKFYTR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0126 10.7331 0 0 Q9UP65 PA24C_HUMAN Cytosolic phospholipase A2 gamma (cPLA2-gamma) (EC 3.1.1.4) (Cytosolic lysophospholipase) (EC 3.1.1.5) (Cytosolic lysophospholipid O-acyltransferase) (EC 2.3.1.-) (Phospholipase A2 group IVC) PLA2G4C Homo sapiens (Human) arachidonic acid metabolic process [GO:0019369]; glycerophospholipid catabolic process [GO:0046475]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; lipid droplet formation [GO:0140042]; parturition [GO:0007567]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phospholipid metabolic process [GO:0006644]; platelet activating factor biosynthetic process [GO:0006663] cell cortex [GO:0005938]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; lipid droplet [GO:0005811]; membrane [GO:0016020]; mitochondrial membrane [GO:0031966]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; calcium-dependent phospholipid binding [GO:0005544]; calcium-independent phospholipase A2 activity [GO:0047499]; lysophospholipase activity [GO:0004622]; O-acyltransferase activity [GO:0008374]; phosphatidyl phospholipase B activity [GO:0102545]; phospholipase A1 activity [GO:0008970]; phospholipid binding [GO:0005543] 0.8703 0.04275 ELPESHLSNMK 0 0 0 0 0 0 8.34145 8.7364 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UP79 ATS8_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 8 (ADAM-TS 8) (ADAM-TS8) (ADAMTS-8) (EC 3.4.24.-) (METH-2) (METH-8) ADAMTS8 METH2 Homo sapiens (Human) extracellular matrix organization [GO:0030198]; negative regulation of cell population proliferation [GO:0008285]; proteolysis [GO:0006508] collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576] heparin binding [GO:0008201]; integrin binding [GO:0005178]; low-affinity phosphate transmembrane transporter activity [GO:0009673]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270] 0.87065 0.048107 LFCRARGR 0 0 0 0 0 0 0 0 0 0 0 9.40984 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UP95 S12A4_HUMAN Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (hKCC1) SLC12A4 KCC1 Homo sapiens (Human) ammonium import across plasma membrane [GO:0140157]; cell volume homeostasis [GO:0006884]; chemical synaptic transmission [GO:0007268]; chloride ion homeostasis [GO:0055064]; chloride transmembrane transport [GO:1902476]; monoatomic ion transport [GO:0006811]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805] lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; synapse [GO:0045202] ammonium transmembrane transporter activity [GO:0008519]; ATP binding [GO:0005524]; potassium:chloride symporter activity [GO:0015379]; protein kinase binding [GO:0019901] 0.92378 -1.0118 EGLAHLIQSCGLGGMR 0 10.7259 0 0 0 0 0 0 0 0 0 0 0 8.53407 0 0 0 0 0 0 0 0 0 0 11.2798 0 11.1039 Q9UPA5 BSN_HUMAN Protein bassoon (Zinc finger protein 231) BSN KIAA0434 ZNF231 Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; presynapse to nucleus signaling pathway [GO:0099526]; presynaptic active zone assembly [GO:1904071]; protein localization to synapse [GO:0035418]; regulation of synaptic vesicle cycle [GO:0098693]; synaptic vesicle clustering [GO:0097091] axon [GO:0030424]; cell surface [GO:0009986]; cochlear hair cell ribbon synapse [GO:0098683]; cytoskeleton of presynaptic active zone [GO:0048788]; dendrite [GO:0030425]; excitatory synapse [GO:0060076]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; neuron projection terminus [GO:0044306]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; presynaptic active zone [GO:0048786]; Schaffer collateral - CA1 synapse [GO:0098685]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672] metal ion binding [GO:0046872]; structural constituent of presynaptic active zone [GO:0098882] 0.96885 -6.9384 AEQTNGSKGTAK 0 8.43763 0 0 0 0 0 9.36162 0 0 10.3763 0 0 0 0 0 0 9.59483 0 0 0 10.7584 0 9.9714 0 0 0 Q9UPE1 SRPK3_HUMAN SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1) (Serine/arginine-rich protein-specific kinase 3) (SR-protein-specific kinase 3) (Serine/threonine-protein kinase 23) SRPK3 MSSK1 STK23 Homo sapiens (Human) cell differentiation [GO:0030154]; intracellular signal transduction [GO:0035556]; muscle tissue development [GO:0060537]; peptidyl-serine phosphorylation [GO:0018105]; regulation of mRNA processing [GO:0050684]; skeletal muscle tissue development [GO:0007519]; spliceosomal complex assembly [GO:0000245] cytoplasm [GO:0005737]; nucleus [GO:0005634] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96923 -3.385 GGYHPVKIGDVFNGR 0 0 0 9.43969 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1413 0 0 0 0 0 0 0 Q9UPM8 AP4E1_HUMAN AP-4 complex subunit epsilon-1 (AP-4 adaptor complex subunit epsilon) (Adaptor-related protein complex 4 subunit epsilon-1) (Epsilon subunit of AP-4) (Epsilon-adaptin) AP4E1 Homo sapiens (Human) protein localization [GO:0008104]; protein targeting [GO:0006605]; vesicle-mediated transport [GO:0016192] AP-4 adaptor complex [GO:0030124]; endosome lumen [GO:0031904]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588] cargo adaptor activity [GO:0140312] 0.73211 0.33742 FHLIAPNQVQHIHIK 0 0 0 0 0 0 0 8.67874 9.42626 0 0 0 0 0 0 0 0 9.38332 0 0 0 0 0 0 0 0 0 Q9UPM9 B9D1_HUMAN B9 domain-containing protein 1 (MKS1-related protein 1) B9D1 MKSR1 Homo sapiens (Human) camera-type eye development [GO:0043010]; cilium assembly [GO:0060271]; embryonic digit morphogenesis [GO:0042733]; in utero embryonic development [GO:0001701]; neuroepithelial cell differentiation [GO:0060563]; regulation of protein localization [GO:0032880]; smoothened signaling pathway [GO:0007224]; vasculature development [GO:0001944] centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary transition zone [GO:0035869]; cytosol [GO:0005829]; membrane [GO:0016020]; MKS complex [GO:0036038] hedgehog receptor activity [GO:0008158] 0.87185 0.050312 GYGAVHVPFSPGRHKR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3876 9.77205 0 0 0 0 0 0 0 Q9UPN3 MACF1_HUMAN "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (620 kDa actin-binding protein) (ABP620) (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha)" MACF1 ABP620 ACF7 KIAA0465 KIAA0754 KIAA1251 Homo sapiens (Human) Golgi to plasma membrane protein transport [GO:0043001]; intermediate filament cytoskeleton organization [GO:0045104]; positive regulation of axon extension [GO:0045773]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of cell migration [GO:0030334]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule-based process [GO:0032886]; regulation of neuron projection arborization [GO:0150011]; Wnt signaling pathway [GO:0016055]; wound healing [GO:0042060] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; microtubule [GO:0005874]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587] actin binding [GO:0003779]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; microtubule minus-end binding [GO:0051011]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198] 0.9689 -13.631 ALAGHQGR 9.71999 9.693 10.5327 10.3822 0 9.30367 8.78542 0 11.5932 12.6195 10.6458 10.7768 10.6344 0 9.92391 10.3757 12.1902 10.3249 9.00048 0 0 0 0 0 9.173 9.41181 0 Q9UPN4 CP131_HUMAN Centrosomal protein of 131 kDa (5-azacytidine-induced protein 1) (Pre-acrosome localization protein 1) CEP131 AZI1 KIAA1118 Homo sapiens (Human) cell cycle [GO:0007049]; cilium assembly [GO:0060271]; intraciliary transport involved in cilium assembly [GO:0035735]; intramanchette transport [GO:1990953]; manchette assembly [GO:1905198]; non-motile cilium assembly [GO:1905515]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of intracellular protein transport [GO:0090316]; protein localization to centrosome [GO:0071539]; regulation of centrosome duplication [GO:0010824]; sperm axoneme assembly [GO:0007288] acrosomal vesicle [GO:0001669]; centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary transition zone [GO:0035869]; cytosol [GO:0005829]; manchette [GO:0002177]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; sperm head-tail coupling apparatus [GO:0120212] protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877] 0.96912 -4.2396 ASTAERGPPENPR 0 0 0 0 0 0 0 8.82852 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.425 0 0 Q9UPN7 PP6R1_HUMAN Serine/threonine-protein phosphatase 6 regulatory subunit 1 (SAPS domain family member 1) PPP6R1 KIAA1115 PP6R1 SAPS1 Homo sapiens (Human) regulation of phosphoprotein phosphatase activity [GO:0043666] cytosol [GO:0005829]; nucleus [GO:0005634] protein phosphatase binding [GO:0019903]; protein phosphatase regulator activity [GO:0019888]; small GTPase binding [GO:0031267] 0.56104 0.53299 ILTSWEENDR 0 0 0 0 0 0 0 0 0 0 0 12.7255 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UPN9 TRI33_HUMAN E3 ubiquitin-protein ligase TRIM33 (EC 2.3.2.27) (Ectodermin homolog) (RET-fused gene 7 protein) (Protein Rfg7) (RING-type E3 ubiquitin transferase TRIM33) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33) TRIM33 KIAA1113 RFG7 TIF1G Homo sapiens (Human) negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015] nucleoplasm [GO:0005654]; nucleus [GO:0005634] co-SMAD binding [GO:0070410]; DNA binding [GO:0003677]; R-SMAD binding [GO:0070412]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.91431 -0.7783 QECRQIDLVDNYFVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2613 0 0 0 0 0 0 0 0 0 0 0 Q9UPP1 PHF8_HUMAN Histone lysine demethylase PHF8 (EC 1.14.11.27) (EC 1.14.11.65) (PHD finger protein 8) ([histone H3]-dimethyl-L-lysine(36) demethylase PHF8) ([histone H3]-dimethyl-L-lysine(9) demethylase PHF8) PHF8 KIAA1111 ZNF422 Homo sapiens (Human) brain development [GO:0007420]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of rDNA heterochromatin formation [GO:0061188]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein demethylation [GO:0006482]; regulation of transcription by RNA polymerase II [GO:0006357] nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 2-oxoglutarate-dependent dioxygenase activity [GO:0016706]; chromatin binding [GO:0003682]; histone demethylase activity [GO:0032452]; histone H3K27me2/H3K27me3 demethylase activity [GO:0071558]; histone H3K36 demethylase activity [GO:0051864]; histone H3K36me/H3K36me2 demethylase activity [GO:0140680]; histone H3K9 demethylase activity [GO:0032454]; histone H3K9me/H3K9me2 demethylase activity [GO:0140683]; histone H4K20 demethylase activity [GO:0035575]; iron ion binding [GO:0005506]; methylated histone binding [GO:0035064]; transcription coregulator activity [GO:0003712]; zinc ion binding [GO:0008270] 0.9698 -4.0322 EIDVIDVTRQADCK 0 0 0 0 0 0 0 8.79477 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2454 10.1922 0 0 Q9UPP2 IQEC3_HUMAN IQ motif and SEC7 domain-containing protein 3 IQSEC3 KIAA1110 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; regulation of ARF protein signal transduction [GO:0032012] cytosol [GO:0005829]; GABA-ergic synapse [GO:0098982]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; nucleoplasm [GO:0005654]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization of symmetric synapse [GO:0099629] guanyl-nucleotide exchange factor activity [GO:0005085] 0.17042 0.96924 QIEMLEHK 0 0 0 9.18649 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1029 Q9UPQ0 LIMC1_HUMAN LIM and calponin homology domains-containing protein 1 LIMCH1 KIAA1102 Homo sapiens (Human) actomyosin structure organization [GO:0031032]; cytoplasmic actin-based contraction involved in cell motility [GO:0060327]; negative regulation of cell migration [GO:0030336]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of stress fiber assembly [GO:0051496]; regulation of focal adhesion assembly [GO:0051893] cytoplasm [GO:0005737]; stress fiber [GO:0001725] actin binding [GO:0003779]; metal ion binding [GO:0046872]; myosin II head/neck binding [GO:0032034] 0.96092 -2.0097 EEDDKWQDDLAR 10.2264 0 0 0 0 9.63303 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UPQ4 TRI35_HUMAN E3 ubiquitin-protein ligase TRIM35 (EC 2.3.2.27) (Hemopoietic lineage switch protein 5) TRIM35 HLS5 KIAA1098 Homo sapiens (Human) apoptotic process [GO:0006915]; innate immune response [GO:0045087]; negative regulation of mitotic cell cycle [GO:0045930]; positive regulation of apoptotic process [GO:0043065]; protein ubiquitination [GO:0016567]; suppression of viral release by host [GO:0044790] cytoplasm [GO:0005737]; nucleus [GO:0005634] ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] 0.95547 -1.5849 QEFDKLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.3614 0 0 0 0 Q9UPQ7 PZRN3_HUMAN E3 ubiquitin-protein ligase PDZRN3 (EC 2.3.2.27) (Ligand of Numb protein X 3) (PDZ domain-containing RING finger protein 3) (RING-type E3 ubiquitin transferase PDZRN3) (Semaphorin cytoplasmic domain-associated protein 3) (Protein SEMACAP3) PDZRN3 KIAA1095 LNX3 SEMCAP3 Homo sapiens (Human) neuromuscular junction development [GO:0007528]; protein ubiquitination [GO:0016567] cytoplasm [GO:0005737]; neuromuscular junction [GO:0031594] ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.95879 -1.7828 CDFAPAR 0 0 8.69968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UPQ9 TNR6B_HUMAN Trinucleotide repeat-containing gene 6B protein TNRC6B KIAA1093 Homo sapiens (Human) "miRNA-mediated gene silencing [GO:0035195]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; RNA-mediated gene silencing [GO:0031047]" cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932] RNA binding [GO:0003723] 0.96969 -3.947 DQGWGGGRQPNQGWSSGK 0 10.7317 0 10.1161 10.3337 10.0188 0 0 0 0 0 9.03397 9.85471 0 0 0 0 9.28967 0 0 0 0 0 0 0 0 10.2963 Q9UPR0 PLCL2_HUMAN Inactive phospholipase C-like protein 2 (PLC-L(2)) (PLC-L2) (Phospholipase C-L2) (Phospholipase C-epsilon-2) (PLC-epsilon-2) PLCL2 KIAA1092 PLCE2 Homo sapiens (Human) "B cell proliferation involved in immune response [GO:0002322]; B-1a B cell differentiation [GO:0002337]; gamma-aminobutyric acid signaling pathway [GO:0007214]; intracellular signal transduction [GO:0035556]; lipid metabolic process [GO:0006629]; negative regulation of B cell receptor signaling pathway [GO:0050859]; negative regulation of cold-induced thermogenesis [GO:0120163]; positive regulation of receptor binding [GO:1900122]; regulation of synaptic transmission, GABAergic [GO:0032228]" cytoplasm [GO:0005737] "GABA receptor binding [GO:0050811]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol phospholipase C activity [GO:0004435]" 0.96857 -3.9137 DKAGTEVTK 0 0 0 0 0 0 0 0 0 9.66156 0 0 0 0 0 0 0 9.33199 0 0 0 0 0 0 0 0 0 Q9UPR3 SMG5_HUMAN Nonsense-mediated mRNA decay factor SMG5 (EST1-like protein B) (LPTS-RP1) (LPTS-interacting protein) (SMG-5 homolog) (hSMG-5) SMG5 EST1B KIAA1089 Homo sapiens (Human) "mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of dephosphorylation [GO:0035303]; regulation of telomere maintenance [GO:0032204]; regulation of telomere maintenance via telomerase [GO:0032210]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; telomerase holoenzyme complex [GO:0005697] histone deacetylase binding [GO:0042826]; protein phosphatase 2A binding [GO:0051721]; telomerase RNA binding [GO:0070034]; telomeric DNA binding [GO:0042162]; ubiquitin protein ligase binding [GO:0031625] 0.95821 -1.6836 LMRDMAQLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.98285 0 0 0 0 0 0 0 0 Q9UPR6 ZFR2_HUMAN Zinc finger RNA-binding protein 2 ZFR2 KIAA1086 Homo sapiens (Human) double-stranded RNA binding [GO:0003725]; single-stranded RNA binding [GO:0003727]; zinc ion binding [GO:0008270] 0.96189 -2.0417 VLEERMR 9.85451 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UPS6 SET1B_HUMAN Histone-lysine N-methyltransferase SETD1B (EC 2.1.1.364) (Lysine N-methyltransferase 2G) (SET domain-containing protein 1B) (hSET1B) SETD1B KIAA1076 KMT2G SET1B Homo sapiens (Human) histone H3-K4 methylation [GO:0051568] chromosome [GO:0005694]; histone methyltransferase complex [GO:0035097]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; Set1C/COMPASS complex [GO:0048188] histone H3K4 monomethyltransferase activity [GO:0140945]; histone H3K4 trimethyltransferase activity [GO:0140999]; RNA binding [GO:0003723] 0.057613 1.3798 APAPPPLPPAEPLAK 0 0 0 0 9.42738 0 0 10.5344 0 0 0 9.61939 0 0 0 10.3844 0 9.99081 0 0 0 0 0 0 0 0 0 Q9UPS8 ANR26_HUMAN Ankyrin repeat domain-containing protein 26 ANKRD26 KIAA1074 Homo sapiens (Human) negative regulation of fat cell differentiation [GO:0045599] centrosome [GO:0005813] 0.96863 -7.7985 DLGKIHKAASAGNVAK 0 0 0 0 0 0 0 0 9.26945 0 0 0 0 0 0 9.79006 0 0 0 0 0 0 0 0 10.1076 0 12.3749 Q9UPT5 EXOC7_HUMAN Exocyst complex component 7 (Exocyst complex component Exo70) EXOC7 EXO70 KIAA1067 Homo sapiens (Human) exocytosis [GO:0006887]; membrane fission [GO:0090148]; mitotic cytokinesis [GO:0000281]; protein transport [GO:0015031]; regulation of entry of bacterium into host cell [GO:2000535]; regulation of macroautophagy [GO:0016241]; vesicle docking involved in exocytosis [GO:0006904]; vesicle tethering involved in exocytosis [GO:0090522] centriolar satellite [GO:0034451]; cytosol [GO:0005829]; exocyst [GO:0000145]; Flemming body [GO:0090543]; growth cone membrane [GO:0032584]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; plasma membrane [GO:0005886] "phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]" 0.96363 -2.6523 LLSTYICK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.68564 0 9.70981 0 0 0 0 0 0 0 Q9UPT8 ZC3H4_HUMAN Zinc finger CCCH domain-containing protein 4 ZC3H4 C19orf7 KIAA1064 Homo sapiens (Human) "DNA-templated transcription termination [GO:0006353]; lncRNA catabolic process [GO:0110064]; negative regulation of DNA-templated transcription, elongation [GO:0032785]; negative regulation of lncRNA transcription [GO:0140744]; nuclear RNA surveillance [GO:0071027]" chromosome [GO:0005694]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] metal ion binding [GO:0046872]; promoter-specific chromatin binding [GO:1990841]; RNA binding [GO:0003723] 0.95813 -1.6712 ELNQYRRAK 8.19687 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UPU3 SORC3_HUMAN VPS10 domain-containing receptor SorCS3 SORCS3 KIAA1059 Homo sapiens (Human) learning [GO:0007612]; memory [GO:0007613]; neuropeptide signaling pathway [GO:0007218]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of long-term synaptic depression [GO:1900452] glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; postsynaptic density membrane [GO:0098839] neuropeptide receptor activity [GO:0008188] 0.96951 -3.5283 GGEMQVEAGGTSPAGERRGR 0 0 0 0 0 0 0 0 9.86649 0 0 0 0 11.266 11.0625 0 0 11.9819 0 0 0 10.722 0 0 0 0 0 Q9UPU5 UBP24_HUMAN Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) USP24 KIAA1057 Homo sapiens (Human) protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] cysteine-type deubiquitinase activity [GO:0004843]; cysteine-type endopeptidase activity [GO:0004197] 0.97008 -4.1327 EARFETTSGK 0 0 11.4052 0 0 0 0 0 0 0 9.7389 9.62617 0 0 0 0 0 0 0 0 0 0 9.08388 0 0 0 10.7269 Q9UPU7 TBD2B_HUMAN TBC1 domain family member 2B TBC1D2B KIAA1055 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; endocytosis [GO:0006897] cytosol [GO:0005829]; early endosome [GO:0005769] GTPase activator activity [GO:0005096] 0.9677 -3.7443 DNLQGYKTQNK 0 0 0 0 0 0 0 0 0 8.91148 11.9707 0 0 11.7688 0 0 0 0 0 0 0 0 9.8378 0 0 0 0 Q9UPU9 SMAG1_HUMAN Protein Smaug homolog 1 (Smaug 1) (hSmaug1) (Sterile alpha motif domain-containing protein 4A) (SAM domain-containing protein 4A) SAMD4A KIAA1053 SAMD4 SMAUG1 Homo sapiens (Human) nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of translation [GO:0045727] cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; P-body [GO:0000932]; synapse [GO:0045202] mRNA binding [GO:0003729]; RNA binding [GO:0003723]; translation repressor activity [GO:0030371] 0.96211 -2.6139 DIIEGGSLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1421 0 9.95735 0 0 0 0 0 0 0 0 0 0 Q9UPV0 CE164_HUMAN Centrosomal protein of 164 kDa (Cep164) CEP164 KIAA1052 NPHP15 Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; cilium assembly [GO:0060271]; DNA repair [GO:0006281] centriole [GO:0005814]; centrosome [GO:0005813]; ciliary transition fiber [GO:0097539]; cytosol [GO:0005829]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654] 0.96715 -3.7685 AELLGHLTGELERLQR 0 0 0 9.6566 9.83588 9.57395 0 0 0 12.0092 11.1862 11.2884 8.99475 9.70077 0 0 0 0 0 0 0 0 0 0 0 10.2536 0 Q9UPV9 TRAK1_HUMAN Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase-interacting protein) (Protein Milton) TRAK1 KIAA1042 OIP106 Homo sapiens (Human) anterograde axonal transport of mitochondrion [GO:0098957]; endosome to lysosome transport [GO:0008333]; mitochondrion distribution [GO:0048311]; neurogenesis [GO:0022008]; protein O-linked glycosylation [GO:0006493]; protein targeting [GO:0006605]; regulation of transcription by RNA polymerase II [GO:0006357]; vesicle transport along microtubule [GO:0047496] axon cytoplasm [GO:1904115]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; early endosome [GO:0005769]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634] GABA receptor binding [GO:0050811]; myosin binding [GO:0017022] 0.87584 -0.0016445 TETITYEEK 0 0 0 0 0 0 0 8.76822 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UPW0 FOXJ3_HUMAN Forkhead box protein J3 FOXJ3 KIAA1041 Homo sapiens (Human) cell differentiation [GO:0030154]; male meiosis I [GO:0007141]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.87669 -0.0010168 NALLDPNTTLDQEEVQQHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.8417 0 0 0 0 Q9UPW5 CBPC1_HUMAN Cytosolic carboxypeptidase 1 (EC 3.4.17.-) (EC 3.4.17.24) (ATP/GTP-binding protein 1) (Nervous system nuclear protein induced by axotomy protein 1 homolog) (Protein deglutamylase CCP1) AGTPBP1 CCP1 KIAA1035 NNA1 Homo sapiens (Human) adult walking behavior [GO:0007628]; anterograde axonal transport of mitochondrion [GO:0098957]; C-terminal protein deglutamylation [GO:0035609]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; eye photoreceptor cell differentiation [GO:0001754]; mitochondrion organization [GO:0007005]; negative regulation of cell population proliferation [GO:0008285]; neuromuscular process [GO:0050905]; neurotransmitter metabolic process [GO:0042133]; olfactory bulb development [GO:0021772]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein deglutamylation [GO:0035608]; protein side chain deglutamylation [GO:0035610]; proteolysis [GO:0006508]; retina development in camera-type eye [GO:0060041]; retrograde axonal transport of mitochondrion [GO:0098958] axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634] metallocarboxypeptidase activity [GO:0004181]; tubulin binding [GO:0015631]; zinc ion binding [GO:0008270] 0.95439 -1.5298 FCVGLLRLK 0 0 0 0 0 0 0 0 11.9263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UPW6 SATB2_HUMAN DNA-binding protein SATB2 (Special AT-rich sequence-binding protein 2) SATB2 KIAA1034 Homo sapiens (Human) cartilage development [GO:0051216]; cellular response to organic substance [GO:0071310]; chromatin remodeling [GO:0006338]; embryonic pattern specification [GO:0009880]; embryonic skeletal system morphogenesis [GO:0048704]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron migration [GO:0001764]; osteoblast development [GO:0002076]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; roof of mouth development [GO:0060021] chromatin [GO:0000785]; histone deacetylase complex [GO:0000118]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; transcription regulator complex [GO:0005667] "chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone deacetylase binding [GO:0042826]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.96221 -2.0792 CQEFGRWYKK 0 0 0 0 0 0 0 9.55861 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6284 0 0 0 0 0 Q9UPW8 UN13A_HUMAN Protein unc-13 homolog A (Munc13-1) UNC13A KIAA1032 Homo sapiens (Human) "cell differentiation [GO:0030154]; dense core granule priming [GO:0061789]; neuromuscular junction development [GO:0007528]; neuronal dense core vesicle exocytosis [GO:0099011]; neurotransmitter secretion [GO:0007269]; positive regulation of dendrite extension [GO:1903861]; presynaptic dense core vesicle exocytosis [GO:0099525]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]; synaptic vesicle docking [GO:0016081]; synaptic vesicle maturation [GO:0016188]; synaptic vesicle priming [GO:0016082]" neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; presynaptic active zone [GO:0048786]; presynaptic active zone cytoplasmic component [GO:0098831]; presynaptic membrane [GO:0042734]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195] calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; diacylglycerol binding [GO:0019992]; phospholipid binding [GO:0005543]; syntaxin-1 binding [GO:0017075] 0.88239 -0.11384 DHMVREEAK 9.33065 0 0 10.1576 9.02639 9.04971 9.54063 0 11.7947 14.3389 13.7937 13.6253 0 0 0 9.90943 11.9665 0 0 0 8.53201 0 0 0 0 0 0 Q9UPX0 TUTLB_HUMAN Protein turtle homolog B (Immunoglobulin superfamily member 9B) (IgSF9B) IGSF9B KIAA1030 Homo sapiens (Human) cell adhesion [GO:0007155]; nervous system development [GO:0007399] GABA-ergic synapse [GO:0098982]; neuron projection [GO:0043005]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization of symmetric synapse [GO:0099629] 0.96767 -2.8182 ASLRLEQVR 0 0 0 0 0 0 0 0 0 10.0542 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UPX6 MNAR1_HUMAN Major intrinsically disordered Notch2-binding receptor 1 (Membrane integral NOTCH2-associated receptor 1) (Ubiquitination and mTOR signaling protein) MINAR1 KIAA1024 UBTOR Homo sapiens (Human) angiogenesis [GO:0001525]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of TOR signaling [GO:0032007] plasma membrane [GO:0005886] 0.96175 -2.0506 CRKMDCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.56742 0 0 0 Q9UPX8 SHAN2_HUMAN SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin-binding protein 1) (CortBP1) (Proline-rich synapse-associated protein 1) SHANK2 CORTBP1 KIAA1022 PROSAP1 Homo sapiens (Human) adult behavior [GO:0030534]; adult locomotory behavior [GO:0008344]; associative learning [GO:0008306]; brain development [GO:0007420]; learning [GO:0007612]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; negative regulation of hippo signaling [GO:0035331]; positive regulation of cell population proliferation [GO:0008284]; regulation of postsynapse organization [GO:0099175]; response to nutrient [GO:0007584]; response to xenobiotic stimulus [GO:0009410]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; vocalization behavior [GO:0071625] apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; ciliary membrane [GO:0060170]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynaptic active zone [GO:0048786] ionotropic glutamate receptor binding [GO:0035255]; SH3 domain binding [GO:0017124]; structural constituent of postsynaptic density [GO:0098919]; synaptic receptor adaptor activity [GO:0030160] 0.92624 -1.2135 NGGAHLDFRAK 0 0 11.7284 9.2775 9.53545 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UPY3 DICER_HUMAN Endoribonuclease Dicer (EC 3.1.26.3) (Helicase with RNase motif) (Helicase MOI) DICER1 DICER HERNA KIAA0928 Homo sapiens (Human) "apoptotic DNA fragmentation [GO:0006309]; global gene silencing by mRNA cleavage [GO:0098795]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; negative regulation of gene expression [GO:0010629]; negative regulation of Schwann cell proliferation [GO:0010626]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor production [GO:0032720]; nerve development [GO:0021675]; neuron projection morphogenesis [GO:0048812]; NIK/NF-kappaB signaling [GO:0038061]; peripheral nervous system myelin formation [GO:0032290]; positive regulation of myelination [GO:0031643]; positive regulation of Schwann cell differentiation [GO:0014040]; pre-miRNA processing [GO:0031054]; RISC complex assembly [GO:0070922]; RNA phosphodiester bond hydrolysis [GO:0090501]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; siRNA processing [GO:0030422]; tRNA catabolic process [GO:0016078]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; RISC complex [GO:0016442]; RISC-loading complex [GO:0070578] ATP binding [GO:0005524]; deoxyribonuclease I activity [GO:0004530]; DNA binding [GO:0003677]; double-stranded RNA binding [GO:0003725]; helicase activity [GO:0004386]; metal ion binding [GO:0046872]; pre-miRNA binding [GO:0070883]; protein domain specific binding [GO:0019904]; ribonuclease III activity [GO:0004525]; RNA binding [GO:0003723]; RNA endonuclease activity [GO:0004521]; siRNA binding [GO:0035197] 0.96988 -4.2754 ALPLSSAEKR 0 9.57577 0 0 8.84169 0 0 0 0 0 0 9.8932 0 0 0 0 0 0 10.9292 0 0 0 0 0 9.9083 0 0 Q9UPY8 MARE3_HUMAN Microtubule-associated protein RP/EB family member 3 (EB1 protein family member 3) (EBF3) (End-binding protein 3) (EB3) (RP3) MAPRE3 Homo sapiens (Human) cell division [GO:0051301]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of microtubule plus-end binding [GO:1903033]; positive regulation of protein kinase activity [GO:0045860]; protein localization [GO:0008104]; protein localization to microtubule [GO:0035372]; regulation of microtubule polymerization [GO:0031113]; regulation of microtubule polymerization or depolymerization [GO:0031110]; spindle assembly [GO:0051225] cytoplasm [GO:0005737]; microtubule cytoskeleton [GO:0015630]; microtubule organizing center [GO:0005815]; microtubule plus-end [GO:0035371]; midbody [GO:0030496]; mitotic spindle astral microtubule end [GO:1905721]; perinuclear region of cytoplasm [GO:0048471]; spindle midzone [GO:0051233] identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein kinase binding [GO:0019901] 0.92608 -0.96244 DFYFSKLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.40035 0 0 0 0 0 0 0 Q9UPZ3 HPS5_HUMAN BLOC-2 complex member HPS5 (Alpha-integrin-binding protein 63) (Hermansky-Pudlak syndrome 5 protein) (Ruby-eye protein 2 homolog) (Ru2) HPS5 AIBP63 KIAA1017 Homo sapiens (Human) blood coagulation [GO:0007596]; developmental pigmentation [GO:0048066]; intracellular transport [GO:0046907]; melanosome assembly [GO:1903232]; platelet dense granule organization [GO:0060155] BLOC-2 complex [GO:0031084]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769] 0.9691 -3.5946 DFSGVSDTDNSSMK 0 0 0 0 0 0 0 0 9.24203 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UPZ6 THS7A_HUMAN "Thrombospondin type-1 domain-containing protein 7A [Cleaved into: Thrombospondin type-1 domain-containing protein 7A, soluble form]" THSD7A KIAA0960 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; angiogenesis [GO:0001525]; cell differentiation [GO:0030154] cell projection [GO:0042995]; extracellular region [GO:0005576]; plasma membrane [GO:0005886] 0.97001 -5.2143 AVCGNGIKTRMLDCVR 8.61482 0 0 0 0 0 8.30779 0 0 0 0 0 0 0 0 0 0 9.61598 0 0 0 0 0 0 0 0 0 Q9UQ03 COR2B_HUMAN Coronin-2B (Coronin-like protein C) (Clipin-C) (Protein FC96) CORO2B KIAA0925 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; focal adhesion assembly [GO:0048041]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of establishment of protein localization [GO:1904950]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of establishment of protein localization [GO:1904951]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cellular response to stress [GO:0080135]; regulation of glomerular filtration [GO:0003093] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; focal adhesion [GO:0005925]; membrane [GO:0016020] actin binding [GO:0003779]; actin filament binding [GO:0051015]; talin binding [GO:1990147]; vinculin binding [GO:0017166] 0.96189 -2.4888 GLGVMPK 0 9.44359 0 9.91341 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UQ05 KCNH4_HUMAN Potassium voltage-gated channel subfamily H member 4 (Brain-specific eag-like channel 2) (BEC2) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Voltage-gated potassium channel subunit Kv12.3) KCNH4 Homo sapiens (Human) potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of membrane potential [GO:0042391]; regulation of monoatomic ion transmembrane transport [GO:0034765] plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076] voltage-gated potassium channel activity [GO:0005249] 0.96886 -3.0177 ADIAMHLNR 0 0 0 0 0 0 0 0 0 10.9285 9.19173 0 0 0 0 9.32341 0 0 0 0 0 0 0 9.34207 9.60082 0 0 Q9UQ13 SHOC2_HUMAN Leucine-rich repeat protein SHOC-2 (Protein soc-2 homolog) (Protein sur-8 homolog) SHOC2 KIAA0862 Homo sapiens (Human) fibroblast growth factor receptor signaling pathway [GO:0008543]; positive regulation of Ras protein signal transduction [GO:0046579]; Ras protein signal transduction [GO:0007265] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein phosphatase type 1 complex [GO:0000164] protein phosphatase 1 binding [GO:0008157]; protein phosphatase binding [GO:0019903]; protein phosphatase regulator activity [GO:0019888] 0.88893 -0.43038 ASGGFGK 9.11382 9.24124 9.10208 8.88026 0 0 8.47123 0 0 9.79203 0 9.4675 10.8364 8.52458 0 0 0 9.68199 8.4216 9.34718 8.97154 10.4063 10.8871 10.8049 10.3406 0 9.17468 Q9UQ16 DYN3_HUMAN "Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin)" DNM3 KIAA0820 Homo sapiens (Human) endocytosis [GO:0006897]; filopodium assembly [GO:0046847]; negative regulation of dendritic spine morphogenesis [GO:0061002]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of synaptic vesicle recycling [GO:1903423]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; receptor internalization [GO:0031623]; synapse assembly [GO:0007416]; synaptic vesicle endocytosis [GO:0048488] apical tubulobulbar complex [GO:0061828]; axon [GO:0030424]; basal tubulobulbar complex [GO:0061829]; cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; dendritic spine head [GO:0044327]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; microtubule [GO:0005874]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic endocytic zone membrane [GO:0098844]; presynapse [GO:0098793]; synaptic cleft [GO:0043083] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; nitric-oxide synthase binding [GO:0050998]; protein serine/threonine kinase binding [GO:0120283]; structural constituent of postsynapse [GO:0099186]; type 1 metabotropic glutamate receptor binding [GO:0031798]; type 5 metabotropic glutamate receptor binding [GO:0031802] 0.96969 -4.0146 DTLPNFRNK 0 0 0 0 0 0 9.102 0 0 0 9.67557 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4095 Q9UQ26 RIMS2_HUMAN Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3) RIMS2 KIAA0751 RAB3IP3 RIM2 Homo sapiens (Human) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; regulation of synaptic plasticity [GO:0048167]; regulation of synaptic vesicle exocytosis [GO:2000300]; spontaneous neurotransmitter secretion [GO:0061669] cell projection [GO:0042995]; cytoskeleton of presynaptic active zone [GO:0048788]; extracellular exosome [GO:0070062]; presynaptic active zone [GO:0048786]; presynaptic membrane [GO:0042734] metal ion binding [GO:0046872]; small GTPase binding [GO:0031267]; transmembrane transporter binding [GO:0044325] 0.96937 -5.5526 CGGRVSLRSNK 0 0 0 10.189 0 11.669 0 0 0 13.599 0 0 0 8.84543 0 0 9.26195 0 0 0 0 0 9.88457 0 0 0 10.8391 Q9UQ35 SRRM2_HUMAN Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803) SRRM2 KIAA0324 SRL300 SRM300 HSPC075 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]" Cajal body [GO:0015030]; catalytic step 2 spliceosome [GO:0071013]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005] C2H2 zinc finger domain binding [GO:0070742]; mRNA binding [GO:0003729]; RNA binding [GO:0003723] 0.9692 -5.72 DRSGSSQSTSRR 12.576 0 9.32814 0 0 0 9.96117 0 0 12.2765 0 0 0 9.75929 0 10.0664 0 0 0 0 8.65094 9.63127 0 0 10.4407 11.4568 10.4008 Q9UQ52 CNTN6_HUMAN Contactin-6 (Neural recognition molecule NB-3) (hNB-3) CNTN6 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; dendrite self-avoidance [GO:0070593]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; Notch signaling pathway [GO:0007219]; positive regulation of Notch signaling pathway [GO:0045747] axon [GO:0030424]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734] cell-cell adhesion mediator activity [GO:0098632] 0.96706 -3.7591 AKLQFAYIEDFETK 0 0 0 0 9.47669 0 0 0 0 0 0 0 0 0 8.69853 0 0 0 0 0 0 0 0 0 8.62227 8.17283 0 Q9UQ80 PA2G4_HUMAN Proliferation-associated protein 2G4 (Cell cycle protein p38-2G4 homolog) (hG4-1) (ErbB3-binding protein 1) PA2G4 EBP1 Homo sapiens (Human) negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of cell differentiation [GO:0045597]; regulation of translation [GO:0006417]; rRNA processing [GO:0006364] azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] nucleic acid binding [GO:0003676]; RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625] 0.88178 -0.099878 AFFSEVER 0 0 0 0 0 0 0 10.5343 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UQ84 EXO1_HUMAN Exonuclease 1 (hExo1) (EC 3.1.-.-) (Exonuclease I) (hExoI) EXO1 EXOI HEX1 Homo sapiens (Human) DNA recombination [GO:0006310]; DNA repair [GO:0006281]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; isotype switching [GO:0045190]; meiotic cell cycle [GO:0051321]; mismatch repair [GO:0006298]; somatic hypermutation of immunoglobulin genes [GO:0016446]; t-circle formation [GO:0090656] nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] 5'-3' DNA exonuclease activity [GO:0035312]; 5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; double-stranded DNA 5'-3' exodeoxyribonuclease activity [GO:0051908]; exonuclease activity [GO:0004527]; flap endonuclease activity [GO:0048256]; metal ion binding [GO:0046872]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; single-stranded DNA 5'-3' DNA exonuclease activity [GO:0045145] 0.96925 -3.2152 EGKVSEARECFTR 9.33537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.96252 0 0 0 0 0 0 0 0 Q9UQ88 CD11A_HUMAN Cyclin-dependent kinase 11A (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 2) (Cell division protein kinase 11A) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L2) CDK11A CDC2L2 CDC2L3 PITSLREB Homo sapiens (Human) apoptotic process [GO:0006915]; mitotic cell cycle [GO:0000278]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell growth [GO:0001558]; regulation of centrosome cycle [GO:0046605]; regulation of DNA-templated transcription [GO:0006355]; regulation of mitotic cell cycle [GO:0007346]; regulation of mRNA processing [GO:0050684]; regulation of RNA splicing [GO:0043484] cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; nucleus [GO:0005634] ATP binding [GO:0005524]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.96886 -4.2158 EVSAHHRTMREDYSDK 0 0 0 0 0 9.56718 0 0 0 0 0 0 0 0 0 0 0 0 8.67023 0 0 0 0 0 0 0 0 Q9UQ90 SPG7_HUMAN Paraplegin (EC 3.4.24.-) (Cell matrix adhesion regulator) (Spastic paraplegia 7 protein) SPG7 CAR CMAR PGN Homo sapiens (Human) anterograde axonal transport [GO:0008089]; mitochondrial outer membrane permeabilization involved in programmed cell death [GO:1902686]; mitochondrial protein processing [GO:0034982]; nervous system development [GO:0007399]; proteolysis [GO:0006508]; regulation of mitochondrial membrane permeability [GO:0046902] axon cytoplasm [GO:1904115]; m-AAA complex [GO:0005745]; mitochondrial inner membrane [GO:0005743]; mitochondrial permeability transition pore complex [GO:0005757]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent peptidase activity [GO:0004176]; metalloendopeptidase activity [GO:0004222]; peptidase activity [GO:0008233]; unfolded protein binding [GO:0051082]; zinc ion binding [GO:0008270] 0.89854 -0.6495 ADILDGALMRPGR 0 0 0 9.63189 0 0 0 0 0 0 0 0 0 9.51321 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UQB3 CTND2_HUMAN Catenin delta-2 (Delta-catenin) (GT24) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) CTNND2 NPRAP Homo sapiens (Human) cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell junction assembly [GO:0007043]; dendritic spine morphogenesis [GO:0060997]; regulation of canonical Wnt signaling pathway [GO:0060828]; signal transduction [GO:0007165]; synapse organization [GO:0050808]; Wnt signaling pathway [GO:0016055] adherens junction [GO:0005912]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296] 0.95471 -1.6219 AASQVLNSMWQYRDLR 0 0 0 0 0 0 0 10.1529 0 0 0 0 0 0 0 0 10.5617 0 0 8.41452 0 0 0 0 10.124 0 0 Q9UQB8 BAIP2_HUMAN Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI-associated protein 2) (BAI1-associated protein 2) (Protein BAP2) (Fas ligand-associated factor 3) (FLAF3) (Insulin receptor substrate p53/p58) (IRS-58) (IRSp53/58) (Insulin receptor substrate protein of 53 kDa) (IRSp53) (Insulin receptor substrate p53) BAIAP2 Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin filament bundle assembly [GO:0051017]; axonogenesis [GO:0007409]; brain development [GO:0007420]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to L-glutamate [GO:1905232]; dendrite development [GO:0016358]; insulin receptor signaling pathway [GO:0008286]; plasma membrane organization [GO:0007009]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of excitatory postsynaptic potential [GO:2000463]; protein localization to synapse [GO:0035418]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of synaptic plasticity [GO:0048167] "adherens junction [GO:0005912]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; dendritic spine cytoplasm [GO:0061846]; excitatory synapse [GO:0060076]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; lamellipodium [GO:0030027]; microtubule [GO:0005874]; neuron projection branch point [GO:0061845]; neuron projection terminus [GO:0044306]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; postsynaptic density, intracellular component [GO:0099092]; presynaptic cytosol [GO:0099523]; rough endoplasmic reticulum [GO:0005791]; ruffle [GO:0001726]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; synaptic membrane [GO:0097060]" cadherin binding involved in cell-cell adhesion [GO:0098641]; cytoskeletal anchor activity [GO:0008093]; identical protein binding [GO:0042802]; PDZ domain binding [GO:0030165]; proline-rich region binding [GO:0070064]; scaffold protein binding [GO:0097110]; transcription coregulator binding [GO:0001221] 0.88297 -0.070808 EGDLITLLVPEARDGWHYGESEK 12.2204 0 11.9041 11.0672 0 10.8627 0 0 0 0 0 0 0 10.2397 10.3565 0 0 0 0 0 0 0 0 9.35771 9.78642 10.2597 0 Q9UQC2 GAB2_HUMAN GRB2-associated-binding protein 2 (GRB2-associated binder 2) (Growth factor receptor bound protein 2-associated protein 2) (pp100) GAB2 KIAA0571 Homo sapiens (Human) osteoclast differentiation [GO:0030316]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of mast cell degranulation [GO:0043306]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane raft [GO:0045121]; plasma membrane [GO:0005886] "phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]" 0.36861 0.7364 EFGDLLVDNMDVPATPLSAYQIPR 9.98556 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.26606 0 0 0 9.18896 0 0 Q9UQC9 CLCA2_HUMAN "Calcium-activated chloride channel regulator 2 (EC 3.4.-.-) (Calcium-activated chloride channel family member 2) (hCLCA2) (Calcium-activated chloride channel protein 3) (CaCC-3) (hCaCC-3) [Cleaved into: Calcium-activated chloride channel regulator 2, 109 kDa form; Calcium-activated chloride channel regulator 2, 35 kDa form]" CLCA2 CACC3 Homo sapiens (Human) cell adhesion [GO:0007155]; monoatomic ion transmembrane transport [GO:0034220]; proteolysis [GO:0006508] anchoring junction [GO:0070161]; basal plasma membrane [GO:0009925]; cell junction [GO:0030054]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] chloride channel activity [GO:0005254]; intracellular calcium activated chloride channel activity [GO:0005229]; ligand-gated monoatomic ion channel activity [GO:0015276]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222] 0.88474 -0.28535 IYVAIRAMDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5213 0 0 0 0 0 0 0 0 0 0 Q9UQD0 SCN8A_HUMAN Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6) SCN8A MED Homo sapiens (Human) calcium ion import across plasma membrane [GO:0098703]; myelination [GO:0042552]; nervous system development [GO:0007399]; peripheral nervous system development [GO:0007422]; regulation of monoatomic ion transmembrane transport [GO:0034765]; sodium ion transport [GO:0006814] axon [GO:0030424]; axon initial segment [GO:0043194]; cell junction [GO:0030054]; cytoplasmic vesicle [GO:0031410]; membrane [GO:0016020]; node of Ranvier [GO:0033268]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; voltage-gated sodium channel complex [GO:0001518]; Z disc [GO:0030018] ATP binding [GO:0005524]; high voltage-gated calcium channel activity [GO:0008331]; voltage-gated sodium channel activity [GO:0005248] 0.96271 -2.0931 FKCCQVNIEEGLGK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.426 0 0 0 0 0 Q9UQE7 SMC3_HUMAN Structural maintenance of chromosomes protein 3 (SMC protein 3) (SMC-3) (Basement membrane-associated chondroitin proteoglycan) (Bamacan) (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) SMC3 BAM BMH CSPG6 SMC3L1 Homo sapiens (Human) cell division [GO:0051301]; DNA repair [GO:0006281]; establishment of meiotic sister chromatid cohesion [GO:0034089]; establishment of mitotic sister chromatid cohesion [GO:0034087]; meiotic cell cycle [GO:0051321]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; mitotic spindle assembly [GO:0090307]; regulation of DNA replication [GO:0006275]; sister chromatid cohesion [GO:0007062]; stem cell population maintenance [GO:0019827] "chromatin [GO:0000785]; chromosome [GO:0005694]; chromosome, centromeric region [GO:0000775]; cohesin complex [GO:0008278]; cytosol [GO:0005829]; lateral element [GO:0000800]; meiotic cohesin complex [GO:0030893]; mitotic spindle pole [GO:0097431]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]" ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; beta-tubulin binding [GO:0048487]; chromatin binding [GO:0003682]; cohesin loader activity [GO:0061775]; double-stranded DNA binding [GO:0003690]; dynein complex binding [GO:0070840]; mediator complex binding [GO:0036033]; microtubule motor activity [GO:0003777]; protein heterodimerization activity [GO:0046982] 0.96894 -10.826 DLEDTEANKEK 0 0 10.7344 0 0 0 0 9.99492 0 9.4795 0 0 0 10.9871 0 0 0 0 0 0 8.63633 0 9.74772 0 11.5029 10.6411 0 Q9UQF0 SYCY1_HUMAN Syncytin-1 (Endogenous retrovirus group W member 1) (Env-W) (Envelope polyprotein gPr73) (Enverin) (HERV-7q Envelope protein) (HERV-W envelope protein) (HERV-W_7q21.2 provirus ancestral Env polyprotein) (Syncytin) [Cleaved into: Surface protein (SU) (gp50); Transmembrane protein (TM) (gp24)] ERVW-1 ERVWE1 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; myoblast fusion [GO:0007520]; syncytium formation [GO:0006949]; syncytium formation by plasma membrane fusion [GO:0000768] plasma membrane [GO:0005886] 0.68862 0.38672 ALDLLTAER 0 0 0 0 0 0 0 10.2928 10.2837 0 10.9719 10.724 0 0 0 10.3088 0 0 0 0 0 0 0 0 0 0 0 Q9UQM7 KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17) CAMK2A CAMKA KIAA0968 Homo sapiens (Human) angiotensin-activated signaling pathway [GO:0038166]; calcium ion transport [GO:0006816]; cellular response to interferon-beta [GO:0035458]; cellular response to type II interferon [GO:0071346]; dendritic spine development [GO:0060996]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of hydrolase activity [GO:0051346]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine autophosphorylation [GO:1990443]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of endocannabinoid signaling pathway [GO:2000124]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of neuron migration [GO:2001222]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of neurotransmitter secretion [GO:0046928]; response to ischemia [GO:0002931] calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endocytic vesicle membrane [GO:0030666]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic density [GO:0014069] ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; glutamate receptor binding [GO:0035254]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.87031 0.052484 VLAGQEYAAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5366 0 0 Q9UQP3 TENN_HUMAN Tenascin-N (TN-N) (Tenascin-W) (TN-W) TNN TNW Homo sapiens (Human) axonogenesis [GO:0007409]; cell-matrix adhesion [GO:0007160]; dendrite self-avoidance [GO:0070593]; negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation [GO:1905240]; negative regulation of neuron migration [GO:2001223]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of osteoblast proliferation [GO:0033689]; neuron projection extension [GO:1990138]; osteoblast development [GO:0002076]; positive regulation of neuron projection development [GO:0010976]; positive regulation of sprouting angiogenesis [GO:1903672]; regulation of bone development [GO:1903010]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of smooth muscle tissue development [GO:1905899] CA3 pyramidal cell dendrite [GO:0097442]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; hippocampal mossy fiber expansion [GO:1990026]; neuronal cell body [GO:0043025]; tenascin complex [GO:0090733] identical protein binding [GO:0042802]; integrin binding [GO:0005178] 0.96792 -3.6931 ADTNALTEIDSPANLVTDR 0 9.77131 9.64917 10.5109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9UQQ2 SH2B3_HUMAN SH2B adapter protein 3 (Lymphocyte adapter protein) (Lymphocyte-specific adapter protein Lnk) (Signal transduction protein Lnk) SH2B3 LNK Homo sapiens (Human) cellular response to chemokine [GO:1990869]; cellular response to interleukin-3 [GO:0036016]; embryonic hemopoiesis [GO:0035162]; erythrocyte development [GO:0048821]; hematopoietic stem cell differentiation [GO:0060218]; intracellular signal transduction [GO:0035556]; megakaryocyte development [GO:0035855]; monocyte homeostasis [GO:0035702]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of Kit signaling pathway [GO:1900235]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of response to cytokine stimulus [GO:0060761]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; neutrophil homeostasis [GO:0001780]; thrombopoietin-mediated signaling pathway [GO:0038163] cytosol [GO:0005829]; plasma membrane [GO:0005886] protein tyrosine kinase binding [GO:1990782]; signaling receptor complex adaptor activity [GO:0030159]; stem cell factor receptor binding [GO:0005173]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068] 0.959 -1.9583 AELVSLQFTDLFQRYFCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0333 0 0 0 0 10.5565 Q9UQR1 ZN148_HUMAN Zinc finger protein 148 (Transcription factor ZBP-89) (Zinc finger DNA-binding protein 89) ZNF148 ZBP89 Homo sapiens (Human) cellular defense response [GO:0006968]; gamete generation [GO:0007276]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein-containing complex assembly [GO:0065003]; regulation of transcription by RNA polymerase II [GO:0006357]; substantia nigra development [GO:0021762] Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]" 0.87122 0.062281 LEGLFLKCGGIDEMQSSR 0 0 0 0 0 0 0 0 9.03722 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9XRX5 HHLA3_HUMAN HERV-H LTR-associating protein 3 (Human endogenous retrovirus-H long terminal repeat-associating protein 3) HHLA3 Homo sapiens (Human) 0.95511 -1.554 GVPIQTPREHSWISCK 0 0 0 0 0 0 0 0 0 0 0 0 0 12.7444 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y210 TRPC6_HUMAN Short transient receptor potential channel 6 (TrpC6) (Transient receptor protein 6) (TRP-6) TRPC6 TRP6 Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; monoatomic cation transport [GO:0006812]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of ion transmembrane transporter activity [GO:0032414]; regulation of cytosolic calcium ion concentration [GO:0051480]; single fertilization [GO:0007338] cation channel complex [GO:0034703]; cytoplasm [GO:0005737]; membrane [GO:0016020]; plasma membrane [GO:0005886]; slit diaphragm [GO:0036057] "calcium channel activity [GO:0005262]; inositol 1,4,5 trisphosphate binding [GO:0070679]; monoatomic cation channel activity [GO:0005261]; protein homodimerization activity [GO:0042803]; store-operated calcium channel activity [GO:0015279]" 0.96214 -2.0363 ESDEVNEGELK 13.5342 13.726 13.6954 11.4246 11.7401 11.7583 13.4253 13.5492 13.5303 13.2923 12.9438 12.7616 11.6119 11.9056 11.9062 12.4079 12.7913 11.9367 8.96867 0 9.01374 0 0 0 0 0 0 Q9Y216 MTMR7_HUMAN "Myotubularin-related protein 7 (Inositol 1,3-bisphosphate phosphatase) (EC 3.1.3.-) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64)" MTMR7 Homo sapiens (Human) phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; protein dephosphorylation [GO:0006470] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; membrane [GO:0016020] "inositol bisphosphate phosphatase activity [GO:0016312]; phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity [GO:0052629]; phosphatidylinositol-3-phosphate phosphatase activity [GO:0004438]; protein tyrosine phosphatase activity [GO:0004725]" 0.97 -5.3794 LVDRVSPK 0 0 0 0 0 0 0 0 0 0 0 0 12.73 0 0 0 13.6089 13.2781 0 0 0 11.9356 0 11.8655 0 0 0 Q9Y217 MTMR6_HUMAN "Myotubularin-related protein 6 (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64)" MTMR6 Homo sapiens (Human) endocytosis [GO:0006897]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; protein dephosphorylation [GO:0006470] cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; nuclear envelope [GO:0005635]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587] "phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity [GO:0052629]; phosphatidylinositol-3,5-bisphosphate phosphatase activity [GO:0106018]; phosphatidylinositol-3-phosphate phosphatase activity [GO:0004438]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine phosphatase activity [GO:0004725]" 0.94789 -1.3672 ANPVNRYMYVMDTRPK 11.4762 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y219 JAG2_HUMAN Protein jagged-2 (Jagged2) (hJ2) JAG2 Homo sapiens (Human) auditory receptor cell fate commitment [GO:0009912]; cell differentiation [GO:0030154]; epithelial cell apoptotic process involved in palatal shelf morphogenesis [GO:1990134]; gamma-delta T cell differentiation [GO:0042492]; in utero embryonic development [GO:0001701]; morphogenesis of embryonic epithelium [GO:0016331]; Notch signaling pathway [GO:0007219]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of Notch signaling pathway [GO:0045747]; regulation of cell adhesion [GO:0030155]; regulation of cell population proliferation [GO:0042127]; respiratory system process [GO:0003016]; skeletal system development [GO:0001501]; spermatogenesis [GO:0007283]; T cell differentiation [GO:0030217]; thymic T cell selection [GO:0045061] plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; growth factor activity [GO:0008083]; Notch binding [GO:0005112] 0.88183 -0.30104 CECAPGFAGPDCR 0 0 0 0 0 0 0 8.93678 0 9.88142 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y223 GLCNE_HUMAN Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (UDP-GlcNAc-2-epimerase/ManAc kinase) [Includes: UDP-N-acetylglucosamine 2-epimerase (hydrolyzing) (EC 3.2.1.183) (UDP-GlcNAc-2-epimerase) (Uridine diphosphate-N-acetylglucosamine-2-epimerase); N-acetylmannosamine kinase (EC 2.7.1.60) (ManAc kinase)] GNE GLCNE Homo sapiens (Human) cell adhesion [GO:0007155]; N-acetylglucosamine biosynthetic process [GO:0006045]; N-acetylneuraminate metabolic process [GO:0006054]; UDP-N-acetylglucosamine metabolic process [GO:0006047] cytoplasm [GO:0005737]; cytosol [GO:0005829] "ATP binding [GO:0005524]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; N-acylmannosamine kinase activity [GO:0009384]; UDP-N-acetylglucosamine 2-epimerase activity [GO:0008761]" 0.96212 -2.4794 DADTQDK 0 0 0 0 0 0 0 0 0 9.25781 0 0 0 0 0 0 0 0 0 0 0 8.71887 0 0 0 0 0 Q9Y226 S22AD_HUMAN Solute carrier family 22 member 13 (Organic anion transporter 10) (OAT10) (Organic cation transporter-like 3) (ORCTL-3) (ORCTL3) SLC22A13 OCTL1 ORCTL3 Homo sapiens (Human) NAD biosynthesis via nicotinamide riboside salvage pathway [GO:0034356]; negative regulation of fatty acid metabolic process [GO:0045922]; nicotinate transport [GO:2001142]; positive regulation of T cell mediated cytotoxicity directed against tumor cell target [GO:0002854]; urate transport [GO:0015747] apical plasma membrane [GO:0016324]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886] nicotinate transmembrane transporter activity [GO:0090416]; urate transmembrane transporter activity [GO:0015143] 0.80803 0.22959 NEFNLVCDR 0 0 15.967 0 0 0 0 16.1268 0 0 0 0 0 0 0 0 13.7578 0 0 0 0 0 0 9.31635 0 0 0 Q9Y227 ENTP4_HUMAN Ectonucleoside triphosphate diphosphohydrolase 4 (NTPDase 4) (EC 3.6.1.15) (EC 3.6.1.6) (Golgi UDPase) (Lysosomal apyrase-like protein of 70 kDa) (Uridine-diphosphatase) (UDPase) (EC 3.6.1.42) ENTPD4 KIAA0392 LALP70 LYSAL1 Homo sapiens (Human) CTP metabolic process [GO:0046036]; GDP catabolic process [GO:0046712]; nucleobase-containing small molecule catabolic process [GO:0034656]; UDP catabolic process [GO:0006256] autophagosome membrane [GO:0000421]; cytoplasmic vesicle [GO:0031410]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; lysosomal membrane [GO:0005765]; membrane [GO:0016020] CDP phosphatase activity [GO:0036384]; CTPase activity [GO:0043273]; GDP phosphatase activity [GO:0004382]; GTPase activity [GO:0003924]; nucleoside diphosphate phosphatase activity [GO:0017110]; ribonucleoside triphosphate phosphatase activity [GO:0017111]; UDP phosphatase activity [GO:0045134] 0.96205 -2.62 VFVYCWPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2758 0 0 0 0 0 0 0 0 10.2048 0 0 Q9Y230 RUVB2_HUMAN RuvB-like 2 (EC 3.6.4.12) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (51 kDa erythrocyte cytosolic protein) (ECP-51) (INO80 complex subunit J) (Repressing pontin 52) (Reptin 52) (TIP49b) (TIP60-associated protein 54-beta) (TAP54-beta) RUVBL2 INO80J TIP48 TIP49B CGI-46 Homo sapiens (Human) box C/D snoRNP assembly [GO:0000492]; cellular response to estradiol stimulus [GO:0071392]; cellular response to UV [GO:0034644]; chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; establishment of protein localization to chromatin [GO:0071169]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance in response to DNA damage [GO:1904507]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of chromosome organization [GO:0033044]; regulation of DNA repair [GO:0006282]; regulation of DNA replication [GO:0006275]; regulation of DNA strand elongation [GO:0060382]; regulation of DNA-templated transcription [GO:0006355]; regulation of double-strand break repair [GO:2000779]; regulation of embryonic development [GO:0045995]; regulation of transcription by RNA polymerase II [GO:0006357]; telomere maintenance [GO:0000723] centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dynein axonemal particle [GO:0120293]; euchromatin [GO:0000791]; extracellular exosome [GO:0070062]; Ino80 complex [GO:0031011]; membrane [GO:0016020]; MLL1 complex [GO:0071339]; NuA4 histone acetyltransferase complex [GO:0035267]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein folding chaperone complex [GO:0101031]; R2TP complex [GO:0097255]; ribonucleoprotein complex [GO:1990904]; RPAP3/R2TP/prefoldin-like complex [GO:1990062]; Swr1 complex [GO:0000812] ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase binding [GO:0051117]; beta-catenin binding [GO:0008013]; chromatin DNA binding [GO:0031490]; DNA helicase activity [GO:0003678]; identical protein binding [GO:0042802]; promoter-enhancer loop anchoring activity [GO:0140585]; protein homodimerization activity [GO:0042803]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; TBP-class protein binding [GO:0017025]; TFIID-class transcription factor complex binding [GO:0001094]; transcription corepressor activity [GO:0003714]; unfolded protein binding [GO:0051082] 0.95925 -1.8363 FVQCPDGELQKRK 0 0 0 0 0 0 0 0 0 10.9516 0 0 0 0 9.08154 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y233 PDE10_HUMAN "cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (EC 3.1.4.17)" PDE10A Homo sapiens (Human) cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; negative regulation of cGMP-mediated signaling [GO:0010754]; signal transduction [GO:0007165] cytosol [GO:0005829] "3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]" 0.95155 -1.4402 LCRFIMSVK 0 0 0 0 0 0 0 0 0 0 0 0 10.4981 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y238 DLEC1_HUMAN Deleted in lung and esophageal cancer protein 1 (Deleted in lung cancer protein 1) (DLC-1) DLEC1 DLC1 Homo sapiens (Human) cell differentiation [GO:0030154]; defense response to tumor cell [GO:0002357]; negative regulation of cell population proliferation [GO:0008285]; spermatogenesis [GO:0007283] cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829] alpha-tubulin binding [GO:0043014]; beta-tubulin binding [GO:0048487]; tubulin binding [GO:0015631] 0.96956 -5.463 AFKMWNNSK 0 0 0 0 0 0 0 9.07625 0 0 0 0 0 0 0 10.0677 0 0 10.4574 9.34143 0 0 0 10.0048 0 0 0 Q9Y239 NOD1_HUMAN Nucleotide-binding oligomerization domain-containing protein 1 (hNod1) (Caspase recruitment domain-containing protein 4) NOD1 CARD4 Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to muramyl dipeptide [GO:0071225]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; ERK1 and ERK2 cascade [GO:0070371]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of xenophagy [GO:1904417]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165]; xenophagy [GO:0098792] apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; CARD domain binding [GO:0050700]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; identical protein binding [GO:0042802]; molecular function activator activity [GO:0140677]; pattern recognition receptor activity [GO:0038187]; peptidoglycan binding [GO:0042834]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877] 0.89839 -0.60466 LSVNQITDGGVK 0 0 0 0 9.8981 0 0 0 0 0 0 0 0 0 0 0 0 0 9.51771 0 0 0 10.1053 0 0 0 0 Q9Y240 CLC11_HUMAN C-type lectin domain family 11 member A (C-type lectin superfamily member 3) (Lymphocyte secreted C-type lectin) (Osteolectin) (Stem cell growth factor) (p47) CLEC11A CLECSF3 LSLCL SCGF Homo sapiens (Human) ossification [GO:0001503]; positive regulation of cell population proliferation [GO:0008284] cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615] carbohydrate binding [GO:0030246]; growth factor activity [GO:0008083] 0.92303 -1.1575 DAVQALQEAQGR 0 0 0 0 0 0 9.39812 0 0 9.92689 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y243 AKT3_HUMAN RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-3) (Protein kinase B gamma) (PKB gamma) (RAC-PK-gamma) (STK-2) AKT3 PKBG Homo sapiens (Human) brain morphogenesis [GO:0048854]; homeostasis of number of cells within a tissue [GO:0048873]; intracellular signal transduction [GO:0035556]; mitochondrial genome maintenance [GO:0000002]; negative regulation of cellular senescence [GO:2000773]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of angiogenesis [GO:0045766]; positive regulation of artery morphogenesis [GO:1905653]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell size [GO:0045793]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of TOR signaling [GO:0032008]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleus [GO:0005634] ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.92353 -1.1669 FPRTLSSDAK 0 0 0 0 0 0 0 0 0 0 9.67329 0 0 0 0 0 0 0 0 0 10.1088 0 0 0 0 8.89881 0 Q9Y247 FA50B_HUMAN Protein FAM50B (Protein XAP-5-like) FAM50B X5L Homo sapiens (Human) chromatin organization [GO:0006325] intercellular bridge [GO:0045171]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.92545 -0.98118 DESHAGK 0 0 10.6732 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.97757 0 0 Q9Y248 PSF2_HUMAN DNA replication complex GINS protein PSF2 (GINS complex subunit 2) GINS2 PSF2 CGI-122 DC5 HSPC037 Homo sapiens (Human) DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via break-induced replication [GO:0000727]; positive regulation of DNA primase activity [GO:1903934]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264] CMG complex [GO:0071162]; GINS complex [GO:0000811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 0.93254 -1.2633 LEKMRDHER 0 0 0 0 0 0 0 0 0 0 8.99653 0 0 0 0 0 0 0 0 0 0 0 9.328 0 0 0 0 Q9Y250 LZTS1_HUMAN Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer-related gene-coding leucine-zipper motif) (Fez1) LZTS1 FEZ1 Homo sapiens (Human) cell cycle [GO:0007049]; negative regulation of macroautophagy [GO:0016242]; regulation of dendrite morphogenesis [GO:0048814]; regulation of postsynapse assembly [GO:0150052]; regulation of synaptic plasticity [GO:0048167] cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] 0.96217 -2.5105 ESQTEVNAK 0 0 8.83472 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.01355 0 0 0 0 Q9Y251 HPSE_HUMAN Heparanase (EC 3.2.1.166) (Endo-glucoronidase) (Heparanase-1) (Hpa1) [Cleaved into: Heparanase 8 kDa subunit; Heparanase 50 kDa subunit] HPSE HEP HPA HPA1 HPR1 HPSE1 HSE1 Homo sapiens (Human) angiogenesis involved in wound healing [GO:0060055]; cell-matrix adhesion [GO:0007160]; establishment of endothelial barrier [GO:0061028]; Factor XII activation [GO:0002542]; heparan sulfate proteoglycan catabolic process [GO:0030200]; heparin metabolic process [GO:0030202]; inflammatory response [GO:0006954]; positive regulation of angiogenesis [GO:0045766]; positive regulation of autophagy [GO:0010508]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of hair follicle development [GO:0051798]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vascular endothelial growth factor production [GO:0010575]; protein transmembrane transport [GO:0071806]; proteoglycan metabolic process [GO:0006029]; regulation of hair follicle development [GO:0051797]; response to organic substance [GO:0010033]; vascular wound healing [GO:0061042] autophagosome [GO:0005776]; endosome [GO:0005768]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; heparanase complex [GO:1904974]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; specific granule lumen [GO:0035580] beta-glucuronidase activity [GO:0004566]; heparanase activity [GO:0030305]; syndecan binding [GO:0045545] 0.26471 0.84881 ESTFEERSYWQSQVNQDICK 0 0 0 0 0 0 0 0 9.57459 0 0 0 0 0 0 0 0 0 9.143 0 0 0 0 0 0 0 0 Q9Y253 POLH_HUMAN DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein) POLH RAD30 RAD30A XPV Homo sapiens (Human) cellular response to UV-C [GO:0071494]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; pyrimidine dimer repair [GO:0006290]; regulation of DNA repair [GO:0006282]; response to radiation [GO:0009314]; response to UV-C [GO:0010225] cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861] damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872] 0.96245 -2.084 LTKDRNDNDR 0 8.65001 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6372 0 0 0 0 0 0 0 0 0 0 0 Q9Y255 PRLD1_HUMAN "PRELI domain-containing protein 1, mitochondrial (25 kDa protein of relevant evolutionary and lymphoid interest) (Px19-like protein)" PRELID1 PRELI CGI-106 SBBI12 Homo sapiens (Human) apoptotic process [GO:0006915]; intermembrane lipid transfer [GO:0120009]; negative regulation of apoptotic process [GO:0043066]; negative regulation of mitochondrial membrane potential [GO:0010917]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; phospholipid transport [GO:0015914]; positive regulation of cellular respiration [GO:1901857]; positive regulation of endopeptidase activity [GO:0010950]; positive regulation of phospholipid transport [GO:2001140]; positive regulation of T cell apoptotic process [GO:0070234]; regulation of membrane lipid distribution [GO:0097035]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of T cell differentiation [GO:0045580] mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991] 0.92208 -1.1376 EAWVSSSLFGVSR 0 0 0 0 0 0 0 9.86685 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y259 CHKB_HUMAN Choline/ethanolamine kinase (Choline kinase beta) (CK) (CKB) (EC 2.7.1.32) (Choline kinase-like protein) (Ethanolamine kinase) (EK) (EC 2.7.1.82) (Ethanolamine kinase beta) (EKB) (choline/ethanolamine kinase beta) (CKEKB) CHKB CHETK CHKL Homo sapiens (Human) CDP-choline pathway [GO:0006657]; muscle organ development [GO:0007517]; phosphatidylethanolamine biosynthetic process [GO:0006646]; phosphorylation [GO:0016310] cytoplasm [GO:0005737]; cytosol [GO:0005829] ATP binding [GO:0005524]; choline kinase activity [GO:0004103]; ethanolamine kinase activity [GO:0004305] 0.86945 0.067464 LEEDLLVEVSR 8.82509 0 0 0 0 0 0 0 9.46467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y262 EIF3L_HUMAN Eukaryotic translation initiation factor 3 subunit L (eIF3l) (Eukaryotic translation initiation factor 3 subunit 6-interacting protein) (Eukaryotic translation initiation factor 3 subunit E-interacting protein) EIF3L EIF3EIP EIF3S6IP HSPC021 HSPC025 MSTP005 Homo sapiens (Human) formation of cytoplasmic translation initiation complex [GO:0001732]; translational initiation [GO:0006413]; viral translational termination-reinitiation [GO:0075525] cytosol [GO:0005829]; eukaryotic 43S preinitiation complex [GO:0016282]; eukaryotic 48S preinitiation complex [GO:0033290]; eukaryotic translation initiation factor 3 complex [GO:0005852]; fibrillar center [GO:0001650]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; synapse [GO:0045202] RNA binding [GO:0003723]; translation initiation factor activity [GO:0003743] 0.55869 0.54121 VLENIELNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3045 0 0 0 8.99977 0 0 0 0 Q9Y265 RUVB1_HUMAN RuvB-like 1 (EC 3.6.4.12) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (54 kDa erythrocyte cytosolic protein) (ECP-54) (INO80 complex subunit H) (Nuclear matrix protein 238) (NMP 238) (Pontin 52) (TIP49a) (TIP60-associated protein 54-alpha) (TAP54-alpha) RUVBL1 INO80H NMP238 TIP49 TIP49A Homo sapiens (Human) box C/D snoRNP assembly [GO:0000492]; cell cycle [GO:0007049]; cell division [GO:0051301]; chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance in response to DNA damage [GO:1904507]; protein stabilization [GO:0050821]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of chromosome organization [GO:0033044]; regulation of DNA repair [GO:0006282]; regulation of DNA replication [GO:0006275]; regulation of DNA strand elongation [GO:0060382]; regulation of DNA-templated transcription [GO:0006355]; regulation of double-strand break repair [GO:2000779]; regulation of embryonic development [GO:0045995]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; telomere maintenance [GO:0000723] cytosol [GO:0005829]; dynein axonemal particle [GO:0120293]; extracellular exosome [GO:0070062]; Ino80 complex [GO:0031011]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; MLL1 complex [GO:0071339]; NuA4 histone acetyltransferase complex [GO:0035267]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein folding chaperone complex [GO:0101031]; R2TP complex [GO:0097255]; ribonucleoprotein complex [GO:1990904]; RPAP3/R2TP/prefoldin-like complex [GO:1990062]; Swr1 complex [GO:0000812] ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; DNA helicase activity [GO:0003678]; TBP-class protein binding [GO:0017025]; TFIID-class transcription factor complex binding [GO:0001094]; transcription coactivator activity [GO:0003713] 0 3.0662 ALESSIAPIVIFASNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5884 0 0 Q9Y266 NUDC_HUMAN Nuclear migration protein nudC (Nuclear distribution protein C homolog) NUDC Homo sapiens (Human) cell division [GO:0051301]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle organization [GO:0007052]; nuclear migration [GO:0007097]; protein folding [GO:0006457]; response to peptide hormone [GO:0043434] cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; microtubule [GO:0005874]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; nucleoplasm [GO:0005654]; spindle [GO:0005819] cadherin binding [GO:0045296]; unfolded protein binding [GO:0051082] 0.96885 -3.3352 INKMEWWSR 0 0 0 0 0 0 0 9.58524 0 0 0 0 0 8.47565 9.982 0 0 0 0 0 0 0 0 0 0 0 9.8014 Q9Y272 RASD1_HUMAN Dexamethasone-induced Ras-related protein 1 (Activator of G-protein signaling 1) RASD1 AGS1 DEXRAS1 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of DNA-templated transcription [GO:0045892]; nitric oxide mediated signal transduction [GO:0007263]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; sarcoplasmic reticulum [GO:0016529] G-protein beta-subunit binding [GO:0031681]; GTP binding [GO:0005525]; GTPase activity [GO:0003924] 0.9591 -1.763 EKASAGSQAKDK 0 0 0 12.4971 0 0 0 0 10.4088 0 0 9.68105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y275 TN13B_HUMAN "Tumor necrosis factor ligand superfamily member 13B (B lymphocyte stimulator) (BLyS) (B-cell-activating factor) (BAFF) (Dendritic cell-derived TNF-like molecule) (TNF- and APOL-related leukocyte expressed ligand 1) (TALL-1) (CD antigen CD257) [Cleaved into: Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form]" TNFSF13B BAFF BLYS TALL1 TNFSF20 ZTNF4 UNQ401/PRO738 Homo sapiens (Human) B cell costimulation [GO:0031296]; B cell differentiation [GO:0030183]; B cell homeostasis [GO:0001782]; B cell proliferation [GO:0042100]; germinal center formation [GO:0002467]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of germinal center formation [GO:0002636]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; T cell proliferation [GO:0042098]; tumor necrosis factor-mediated signaling pathway [GO:0033209] cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] cytokine activity [GO:0005125]; receptor ligand activity [GO:0048018]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164] 0.84546 0.15321 MDDSTER 0 0 0 0 0 0 0 10.2758 0 0 0 0 0 9.39313 0 0 0 0 0 0 0 0 0 0 9.18167 0 0 Q9Y277 VDAC3_HUMAN Voltage-dependent anion-selective channel protein 3 (VDAC-3) (hVDAC3) (Outer mitochondrial membrane protein porin 3) VDAC3 Homo sapiens (Human) adenine transport [GO:0015853]; sperm mitochondrial sheath assembly [GO:0120317]; spermatogenesis [GO:0007283] extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; pore complex [GO:0046930] nucleotide binding [GO:0000166]; porin activity [GO:0015288]; voltage-gated monoatomic anion channel activity [GO:0008308] 0.90527 -0.72631 DVFNKGYGFGMVK 0 0 0 10.3748 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2788 0 0 0 0 10.6316 Q9Y278 HS3S2_HUMAN Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (3-OST-2) (Heparan sulfate 3-O-sulfotransferase 2) (h3-OST-2) HS3ST2 3OST2 UNQ2442/PRO5004 Homo sapiens (Human) "glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process, enzymatic modification [GO:0015015]" Golgi membrane [GO:0000139]; membrane [GO:0016020] [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity [GO:0008467]; [heparan sulfate]-glucosamine 3-sulfotransferase 2 activity [GO:0033871]; sulfotransferase activity [GO:0008146] 0.56412 0.51393 FYETVGQDFR 9.25165 9.38334 0 0 0 0 9.04037 0 9.5602 10.2074 9.55424 9.61511 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y285 SYFA_HUMAN Phenylalanine--tRNA ligase alpha subunit (EC 6.1.1.20) (CML33) (Phenylalanyl-tRNA synthetase alpha subunit) (PheRS) FARSA FARS FARSL FARSLA Homo sapiens (Human) phenylalanyl-tRNA aminoacylation [GO:0006432]; protein heterotetramerization [GO:0051290] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; phenylalanine-tRNA ligase complex [GO:0009328] ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; RNA binding [GO:0003723]; tRNA binding [GO:0000049] 0.95984 -1.9713 LGEKERSELR 0 0 0 8.83573 0 0 0 9.66302 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y289 SC5A6_HUMAN Sodium-dependent multivitamin transporter (Na(+)-dependent multivitamin transporter) (Solute carrier family 5 member 6) SLC5A6 SMVT Homo sapiens (Human) biotin import across plasma membrane [GO:1905135]; biotin transport [GO:0015878]; iodide transmembrane transport [GO:1904200]; pantothenate transmembrane transport [GO:0015887]; sodium ion transport [GO:0006814]; transport across blood-brain barrier [GO:0150104] apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; membrane [GO:0016020]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506] biotin transmembrane transporter activity [GO:0015225]; pantothenate transmembrane transporter activity [GO:0015233]; sodium-dependent multivitamin transmembrane transporter activity [GO:0008523]; vitamin transmembrane transporter activity [GO:0090482] 0.95916 -1.7161 YLSSRTEK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.70041 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y291 RT33_HUMAN "Small ribosomal subunit protein mS33 (28S ribosomal protein S33, mitochondrial) (MRP-S33) (S33mt)" MRPS33 CGI-139 PTD003 Homo sapiens (Human) mitochondrial translation [GO:0032543]; translation [GO:0006412] mitochondrial inner membrane [GO:0005743]; mitochondrial small ribosomal subunit [GO:0005763]; mitochondrion [GO:0005739] structural constituent of ribosome [GO:0003735] 0.85758 0.1001 LFGEVTRPTNSKSMK 0 0 0 0 0 0 0 0 9.95441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y295 DRG1_HUMAN Developmentally-regulated GTP-binding protein 1 (DRG-1) (Neural precursor cell expressed developmentally down-regulated protein 3) (NEDD-3) (Translation factor GTPase DRG1) (TRAFAC GTPase DRG1) (EC 3.6.5.-) DRG1 NEDD3 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; positive regulation of microtubule polymerization [GO:0031116]; regulation of mitotic spindle assembly [GO:1901673] cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; polysome [GO:0005844] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; potassium ion binding [GO:0030955] 0.93967 -1.3033 IAEIEAEMAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.64622 0 0 0 0 0 0 0 0 0 Q9Y296 TPPC4_HUMAN Trafficking protein particle complex subunit 4 (Hematopoietic stem/progenitor cell protein 172) (Synbindin) (TRS23 homolog) TRAPPC4 SBDN CGI-104 HSPC172 PTD009 Homo sapiens (Human) autophagy [GO:0006914]; COPII vesicle coating [GO:0048208]; dendrite development [GO:0016358]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; vesicle coating [GO:0006901]; vesicle tethering [GO:0099022] cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; TRAPP complex [GO:0030008]; TRAPPII protein complex [GO:1990071]; TRAPPIII protein complex [GO:1990072] 0.88405 -0.25045 AEAEKTFSYPLDLLLK 0 0 0 0 12.9352 0 0 0 0 0 0 0 11.3078 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y297 FBW1A_HUMAN F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit) BTRC BTRCP FBW1A FBXW1A Homo sapiens (Human) branching involved in mammary gland duct morphogenesis [GO:0060444]; cellular response to organic cyclic compound [GO:0071407]; mammary gland epithelial cell proliferation [GO:0033598]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smoothened signaling pathway [GO:0045879]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of proteolysis [GO:0045862]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein dephosphorylation [GO:0006470]; protein destabilization [GO:0031648]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of cell cycle [GO:0051726]; regulation of circadian rhythm [GO:0042752]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of proteasomal protein catabolic process [GO:0061136]; rhythmic process [GO:0048511]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; SCF ubiquitin ligase complex [GO:0019005] beta-catenin binding [GO:0008013]; ligase activity [GO:0016874]; protein dimerization activity [GO:0046983]; protein phosphorylated amino acid binding [GO:0045309]; ubiquitin ligase activator activity [GO:1990757]; ubiquitin ligase-substrate adaptor activity [GO:1990756]; ubiquitin protein ligase activity [GO:0061630] 0.96993 -5.0377 CGRHSLQR 0 10.5166 0 0 0 0 0 0 0 0 9.3484 0 0 0 0 0 0 0 0 0 0 0 0 9.5095 0 0 0 Q9Y2B0 CNPY2_HUMAN Protein canopy homolog 2 (MIR-interacting saposin-like protein) (Putative secreted protein Zsig9) (Transmembrane protein 4) CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 Homo sapiens (Human) negative regulation of gene expression [GO:0010629]; positive regulation of low-density lipoprotein receptor activity [GO:1905599]; regulation of low-density lipoprotein particle clearance [GO:0010988] endoplasmic reticulum [GO:0005783] 0.56333 0.51118 NGESSELDLQGIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.06358 0 0 0 0 0 0 0 0 10.1936 0 0 Q9Y2B4 T53G5_HUMAN TP53-target gene 5 protein (TP53-inducible gene 5 protein) TP53TG5 C20orf10 Homo sapiens (Human) intracellular signal transduction [GO:0035556]; negative regulation of cell growth [GO:0030308] chromosome [GO:0005694]; cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleus [GO:0005634] 0.96185 -2.6158 LRDETEQPVSK 0 0 0 0 0 0 0 0 0 0 0 0 9.91531 0 9.44549 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y2C9 TLR6_HUMAN Toll-like receptor 6 (CD antigen CD286) TLR6 Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular response to amyloid-beta [GO:1904646]; cellular response to diacyl bacterial lipopeptide [GO:0071726]; cellular response to oxidised low-density lipoprotein particle stimulus [GO:0140052]; defense response to bacterium [GO:0042742]; detection of diacyl bacterial lipopeptide [GO:0042496]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of macrophage activation [GO:0043032]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; signal transduction [GO:0007165]; toll-like receptor signaling pathway [GO:0002224]; toll-like receptor TLR6:TLR2 signaling pathway [GO:0038124]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666] Golgi apparatus [GO:0005794]; membrane raft [GO:0045121]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; Toll-like receptor 2-Toll-like receptor 6 protein complex [GO:0035355] "amyloid-beta binding [GO:0001540]; identical protein binding [GO:0042802]; lipopeptide binding [GO:0071723]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; protein heterodimerization activity [GO:0046982]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; Toll-like receptor 2 binding [GO:0035663]; transmembrane signaling receptor activity [GO:0004888]" 0.92422 -1.0253 ALMTQRTYLQWPK 0 0 0 0 10.9938 0 0 0 0 0 0 10.9503 0 0 0 0 0 0 0 10.5823 10.5111 0 10.008 0 0 0 0 Q9Y2D5 AKAP2_HUMAN A-kinase anchor protein 2 (AKAP-2) (AKAP-KL) (Protein kinase A-anchoring protein 2) (PRKA2) AKAP2 KIAA0920 PRKA2 Homo sapiens (Human) 0.88115 -0.30452 DALGDSLQVPVSPSSTTSSRCSSR 0 0 0 10.5109 0 0 0 0 12.3204 0 0 0 0 11.0749 0 0 10.8832 0 0 0 0 0 0 0 0 0 0 Q9Y2D8 ADIP_HUMAN Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain-interacting protein) (SSX2-interacting protein) SSX2IP KIAA0923 Homo sapiens (Human) cell adhesion [GO:0007155]; centrosome cycle [GO:0007098]; cilium assembly [GO:0060271]; intraciliary transport involved in cilium assembly [GO:0035735]; regulation of cell motility [GO:2000145]; regulation of Rac protein signal transduction [GO:0035020] adherens junction [GO:0005912]; cell leading edge [GO:0031252]; centriolar satellite [GO:0034451]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] protein domain specific binding [GO:0019904] 0.96169 -2.5794 DCYLLEEKER 0 0 0 0 0 0 0 0 0 0 0 12.5859 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y2D9 ZN652_HUMAN Zinc finger protein 652 ZNF652 KIAA0924 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]" 0.96951 -4.6632 APVQKAK 0 0 0 0 0 0 0 0 10.7221 0 10.6282 0 10.6822 0 8.79941 0 9.10177 0 0 0 0 9.19061 9.32039 10.4833 0 0 0 Q9Y2E5 MA2B2_HUMAN "Epididymis-specific alpha-mannosidase (EC 3.2.1.24) (Alpha-1,6-mannosidase) (Mannosidase alpha class 2B member 2)" MAN2B2 KIAA0935 Homo sapiens (Human) mannose metabolic process [GO:0006013]; oligosaccharide catabolic process [GO:0009313] extracellular exosome [GO:0070062]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764] alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872] 0.57399 0.47507 ASALLYAGESMFTR 0 9.68774 0 0 0 10.681 10.0244 10.0583 10.1261 0 0 0 0 9.49358 9.61961 0 9.54255 0 0 0 0 0 0 0 0 0 0 Q9Y2E6 DTX4_HUMAN E3 ubiquitin-protein ligase DTX4 (EC 2.3.2.27) (Protein deltex-4) (Deltex4) (RING finger protein 155) (RING-type E3 ubiquitin transferase DTX4) DTX4 KIAA0937 RNF155 Homo sapiens (Human) negative regulation of innate immune response [GO:0045824]; Notch signaling pathway [GO:0007219]; proteasomal protein catabolic process [GO:0010498]; protein ubiquitination [GO:0016567]; regulation of type I interferon production [GO:0032479] centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654] ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.76474 0.28465 SIPGVSNTSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.74977 0 0 0 0 0 Q9Y2F5 ICE1_HUMAN Little elongation complex subunit 1 (Interactor of little elongator complex ELL subunit 1) ICE1 KIAA0947 Homo sapiens (Human) positive regulation of intracellular protein transport [GO:0090316]; positive regulation of protein-containing complex assembly [GO:0031334]; positive regulation of transcription by RNA polymerase III [GO:0045945]; snRNA transcription by RNA polymerase II [GO:0042795]; snRNA transcription by RNA polymerase III [GO:0042796] Cajal body [GO:0015030]; euchromatin [GO:0000791]; histone locus body [GO:0035363]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; transcription elongation factor complex [GO:0008023] protein-macromolecule adaptor activity [GO:0030674] 0.96878 -3.3443 CVPEKPAKAITSSR 0 0 0 9.29724 0 0 0 0 0 12.3229 0 10.9795 0 0 10.0507 0 0 0 0 0 0 0 0 0 0 9.99407 0 Q9Y2F9 BTBD3_HUMAN BTB/POZ domain-containing protein 3 BTBD3 KIAA0952 Homo sapiens (Human) cerebral cortex development [GO:0021987]; dendrite morphogenesis [GO:0048813]; neurogenesis [GO:0022008] cytosol [GO:0005829]; nucleus [GO:0005634] identical protein binding [GO:0042802] 0.94904 -1.3782 GRCDSIQFAVDKR 0 0 0 0 0 9.77396 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.1819 0 0 0 0 Q9Y2G0 EFR3B_HUMAN Protein EFR3 homolog B EFR3B KIAA0953 Homo sapiens (Human) phosphatidylinositol phosphate biosynthetic process [GO:0046854]; protein localization to plasma membrane [GO:0072659] actin cytoskeleton [GO:0015629]; cytosol [GO:0005829]; plasma membrane [GO:0005886] 0.93174 -1.2705 LDRIGAYLSERLIR 0 0 0 0 0 0 0 9.42978 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.37621 0 0 0 Q9Y2G1 MYRF_HUMAN "Myelin regulatory factor (EC 3.4.-.-) (Myelin gene regulatory factor) [Cleaved into: Myelin regulatory factor, N-terminal; Myelin regulatory factor, C-terminal]" MYRF C11orf9 KIAA0954 MRF Homo sapiens (Human) central nervous system myelin maintenance [GO:0032286]; central nervous system myelination [GO:0022010]; oligodendrocyte development [GO:0014003]; oligodendrocyte differentiation [GO:0048709]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of myelination [GO:0031643]; protein autoprocessing [GO:0016540] cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; sequence-specific DNA binding [GO:0043565]" 0.56361 0.49595 LTDNLETR 0 0 0 8.45146 0 8.55186 11.7373 0 0 0 0 0 0 9.65637 0 0 0 0 0 0 0 0 9.57905 0 10.3642 10.7169 0 Q9Y2G3 AT11B_HUMAN Phospholipid-transporting ATPase IF (EC 7.6.2.1) (ATPase IR) (ATPase class VI type 11B) (P4-ATPase flippase complex alpha subunit ATP11B) ATP11B ATPIF ATPIR KIAA0956 Homo sapiens (Human) aminophospholipid transport [GO:0015917]; monoatomic ion transmembrane transport [GO:0034220]; monoatomic ion transport [GO:0006811]; phospholipid translocation [GO:0045332] azurophil granule membrane [GO:0035577]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nuclear inner membrane [GO:0005637]; phospholipid-translocating ATPase complex [GO:1990531]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled intramembrane lipid transporter activity [GO:0140326]; magnesium ion binding [GO:0000287]; monoatomic ion transmembrane transporter activity [GO:0015075]; phosphatidylethanolamine flippase activity [GO:0090555]; phosphatidylserine floppase activity [GO:0090556] 0.92187 -1.1315 AQLTETNAGIK 0 0 8.57145 0 0 0 8.95105 8.95603 0 0 0 0 9.40542 9.18416 0 0 9.46473 0 0 0 0 0 0 0 0 0 0 Q9Y2G4 ANKR6_HUMAN Ankyrin repeat domain-containing protein 6 (Diversin) ANKRD6 KIAA0957 Homo sapiens (Human) "negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of JNK cascade [GO:0046330]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]" cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634] 0.91719 -0.87368 IEEARSQANQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.18306 0 9.31157 0 0 0 0 0 0 Q9Y2G5 OFUT2_HUMAN GDP-fucose protein O-fucosyltransferase 2 (EC 2.4.1.221) (Peptide-O-fucosyltransferase 2) (O-FucT-2) POFUT2 C21orf80 FUT13 KIAA0958 Homo sapiens (Human) fucose metabolic process [GO:0006004]; mesoderm formation [GO:0001707]; positive regulation of protein folding [GO:1903334]; protein O-linked fucosylation [GO:0036066]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gene expression [GO:0010468]; regulation of secretion [GO:0051046] endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794] peptide-O-fucosyltransferase activity [GO:0046922] 0.96756 -2.7884 EYWDTRR 0 0 0 0 0 0 0 0 0 0 0 9.81476 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y2G7 ZFP30_HUMAN Zinc finger protein 30 homolog (Zfp-30) (Zinc finger protein 745) ZFP30 KIAA0961 ZNF745 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.95833 -1.8691 ECGKAFRQCAHLSR 0 0 0 0 0 0 0 0 0 0 10.2495 0 0 0 0 10.7166 0 0 0 0 0 0 0 0 0 0 0 Q9Y2G8 DJC16_HUMAN DnaJ homolog subfamily C member 16 (Endoplasmic reticulum DNA J domain-containing protein 8) (ER-resident protein ERdj8) (ERdj8) DNAJC16 ERDJ8 KIAA0962 Homo sapiens (Human) regulation of autophagosome size [GO:0016243] endoplasmic reticulum membrane [GO:0005789] 0.96097 -2.017 LFHELCPVK 8.68706 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0356 0 0 0 0 0 11.2092 0 0 Q9Y2G9 SBNO2_HUMAN Protein strawberry notch homolog 2 SBNO2 KIAA0963 Homo sapiens (Human) bone mineralization [GO:0030282]; bone trabecula morphogenesis [GO:0061430]; cellular response to interleukin-11 [GO:0071348]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; macrophage activation involved in immune response [GO:0002281]; negative regulation of DNA-templated transcription [GO:0045892]; osteoclast differentiation [GO:0030316]; osteoclast fusion [GO:0072675]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of inflammatory response [GO:0050727] nucleus [GO:0005634] chromatin DNA binding [GO:0031490]; histone binding [GO:0042393] 0.96925 -3.3724 AVLDLQNK 0 0 0 0 0 0 0 11.9253 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y2H0 DLGP4_HUMAN Disks large-associated protein 4 (DAP-4) (PSD-95/SAP90-binding protein 4) (SAP90/PSD-95-associated protein 4) (SAPAP-4) DLGAP4 DAP4 KIAA0964 SAPAP4 Homo sapiens (Human) regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; signaling [GO:0023052] cholinergic synapse [GO:0098981]; glutamatergic synapse [GO:0098978]; neuromuscular junction [GO:0031594]; plasma membrane [GO:0005886]; postsynaptic specialization [GO:0099572] molecular adaptor activity [GO:0060090] 0.92424 -1.0645 GLGDSRPR 9.31567 9.46667 0 0 0 0 0 9.36326 0 0 0 10.1427 0 0 0 0 0 0 9.7066 9.39363 8.85502 10.745 10.6296 9.80594 10.4812 0 11.1518 Q9Y2H1 ST38L_HUMAN Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2) STK38L KIAA0965 NDR2 Homo sapiens (Human) intracellular signal transduction [GO:0035556]; negative regulation of autophagy [GO:0010507]; peptidyl-serine phosphorylation [GO:0018105]; postsynapse organization [GO:0099173]; protein phosphorylation [GO:0006468]; regulation of cellular component organization [GO:0051128] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020] actin binding [GO:0003779]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.94067 -1.3097 TRLGLDDFESLK 0 0 0 0 0 0 0 0 0 0 10.4951 10.2855 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y2H5 PKHA6_HUMAN Pleckstrin homology domain-containing family A member 6 (PH domain-containing family A member 6) (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3) PLEKHA6 KIAA0969 PEPP3 Homo sapiens (Human) 0.95258 -1.4552 GEGDGRGCEK 9.39928 0 0 0 0 0 0 0 9.54005 0 0 0 0 0 0 0 0 8.75819 0 0 0 0 0 0 0 0 0 Q9Y2H6 FND3A_HUMAN Fibronectin type-III domain-containing protein 3A (Human gene expressed in odontoblasts) FNDC3A FNDC3 HUGO KIAA0970 Homo sapiens (Human) cell-cell adhesion [GO:0098609]; fertilization [GO:0009566]; Sertoli cell development [GO:0060009]; spermatid development [GO:0007286] acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; vesicle membrane [GO:0012506] RNA binding [GO:0003723] 0.47141 0.6285 DNGGATINK 12.8401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2076 0 0 0 0 0 0 0 0 0 Q9Y2H8 ZN510_HUMAN Zinc finger protein 510 ZNF510 KIAA0972 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.72552 0.34745 ALNYNENLPK 0 0 10.2999 0 0 0 0 0 0 8.73369 9.29193 0 0 0 0 0 0 0 0 0 0 0 0 9.2555 0 0 0 Q9Y2H9 MAST1_HUMAN Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) MAST1 KIAA0973 SAST Homo sapiens (Human) brain development [GO:0007420]; cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468] axon [GO:0030424]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dendrite [GO:0030425]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.95915 -1.7124 EPSTKGPEEK 11.5353 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.49721 0 0 0 0 0 0 0 0 Q9Y2I1 NISCH_HUMAN Nischarin (Imidazoline receptor 1) (I-1) (IR1) (Imidazoline receptor antisera-selected protein) (hIRAS) (Imidazoline-1 receptor) (I1R) (Imidazoline-1 receptor candidate protein) (I-1 receptor candidate protein) (I1R candidate protein) NISCH IRAS KIAA0975 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; apoptotic process [GO:0006915]; negative regulation of cell migration [GO:0030336]; outer dynein arm assembly [GO:0036158]; Rac protein signal transduction [GO:0016601] cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; intercellular bridge [GO:0045171]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037] alpha-tubulin binding [GO:0043014]; dynein heavy chain binding [GO:0045504]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; phosphatidylinositol binding [GO:0035091] 0.95496 -1.6121 ADFNPMPNR 0 0 0 0 11.3608 0 0 0 0 9.52093 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y2I6 NINL_HUMAN Ninein-like protein NINL KIAA0980 NLP Homo sapiens (Human) microtubule anchoring at centrosome [GO:0034454] centrosome [GO:0005813]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630] calcium ion binding [GO:0005509] 0.95952 -1.9662 DLEFVLK 0 0 0 0 0 0 0 0 0 0 0 8.40808 9.24693 0 9.34283 9.41937 9.28529 0 0 0 0 9.35564 0 0 9.53986 0 0 Q9Y2I7 FYV1_HUMAN 1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase) (Serine-protein kinase PIKFYVE) (EC 2.7.11.1) PIKFYVE KIAA0981 PIP5K3 Homo sapiens (Human) "1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process [GO:1903100]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; intracellular signal transduction [GO:0035556]; melanosome organization [GO:0032438]; myelin assembly [GO:0032288]; neutrophil chemotaxis [GO:0030593]; peptidyl-serine autophosphorylation [GO:0036289]; phagosome maturation [GO:0090382]; phagosome-lysosome fusion [GO:0090385]; phosphatidylinositol 5-phosphate metabolic process [GO:1904562]; phosphatidylinositol biosynthetic process [GO:0006661]; protein localization to nucleus [GO:0034504]; protein targeting to membrane [GO:0006612]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of autophagosome assembly [GO:2000785]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; retrograde transport, endosome to Golgi [GO:0042147]" cell-cell junction [GO:0005911]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi membrane [GO:0000139]; late endosome membrane [GO:0031902]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; vesicle membrane [GO:0012506] "1-phosphatidylinositol-3-phosphate 5-kinase activity [GO:0000285]; 1-phosphatidylinositol-4-phosphate 5-kinase activity [GO:0016308]; 1-phosphatidylinositol-5-kinase activity [GO:0052810]; ATP binding [GO:0005524]; phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity [GO:0043813]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; zinc ion binding [GO:0008270]" 0.96915 -6.8616 DLSGLQGMNGSIQAK 0 0 0 0 0 9.50857 0 0 9.57027 10.3108 10.3028 10.2525 0 0 0 10.2144 0 0 0 9.3944 9.25196 9.47547 0 0 9.6139 0 10.0013 Q9Y2I8 WDR37_HUMAN WD repeat-containing protein 37 WDR37 KIAA0982 Homo sapiens (Human) corpus callosum development [GO:0022038]; lymphocyte homeostasis [GO:0002260] cytoplasm [GO:0005737]; nucleus [GO:0005634] 0.95426 -1.534 AACQLVKEYIGHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.4639 0 0 Q9Y2J0 RP3A_HUMAN Rabphilin-3A (Exophilin-1) RPH3A KIAA0985 Homo sapiens (Human) exocytosis [GO:0006887]; intracellular protein transport [GO:0006886]; regulation of calcium ion-dependent exocytosis [GO:0017158]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle priming [GO:0016082] cytosol [GO:0005829]; dendritic spine [GO:0043197]; extrinsic component of membrane [GO:0019898]; extrinsic component of synaptic vesicle membrane [GO:0098850]; neuron projection [GO:0043005]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672] "calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphate ion binding [GO:0042301]; phosphatidylinositol phosphate binding [GO:1901981]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein-containing complex binding [GO:0044877]; selenium binding [GO:0008430]; small GTPase binding [GO:0031267]; zinc ion binding [GO:0008270]" 0.88344 -0.32104 KTLNPEFNEEFFYDIK 0 0 0 0 0 0 0 0 0 10.6334 10.4329 11.2105 0 0 0 13.3325 0 13.1675 0 0 0 0 0 10.3387 0 0 0 Q9Y2J2 E41L3_HUMAN "Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (Erythrocyte membrane protein band 4.1-like 3) [Cleaved into: Band 4.1-like protein 3, N-terminally processed]" EPB41L3 DAL1 KIAA0987 Homo sapiens (Human) actomyosin structure organization [GO:0031032]; apoptotic process [GO:0006915]; cortical actin cytoskeleton organization [GO:0030866]; cortical cytoskeleton organization [GO:0030865]; myelin maintenance [GO:0043217]; neuron projection morphogenesis [GO:0048812]; paranodal junction assembly [GO:0030913]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; protein localization to plasma membrane [GO:0072659]; regulation of cell shape [GO:0008360] cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; juxtaparanode region of axon [GO:0044224]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886] actin binding [GO:0003779]; cytoskeletal protein-membrane anchor activity [GO:0106006]; structural constituent of cytoskeleton [GO:0005200] 0.92364 -1.05 GGISETRIEK 0 8.97177 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.86966 Q9Y2J4 AMOL2_HUMAN Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP) AMOTL2 KIAA0989 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; angiogenesis [GO:0001525]; establishment of cell polarity involved in ameboidal cell migration [GO:0003365]; hippo signaling [GO:0035329]; regulation of cell migration [GO:0030334]; Wnt signaling pathway [GO:0016055] bicellular tight junction [GO:0005923]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037] 0.96849 -3.8562 ELRHGHVR 9.6831 0 0 9.00262 0 0 10.6451 0 9.69467 0 9.3409 0 0 0 0 0 0 0 10.3694 0 8.72574 0 0 0 9.6825 0 0 Q9Y2J8 PADI2_HUMAN Protein-arginine deiminase type-2 (EC 3.5.3.15) (PAD-H19) (Peptidylarginine deiminase II) (Protein-arginine deiminase type II) PADI2 KIAA0994 PAD2 PDI2 Homo sapiens (Human) cellular response to leukemia inhibitory factor [GO:1990830]; chromatin remodeling [GO:0006338]; intracellular estrogen receptor signaling pathway [GO:0030520]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of lymphocyte chemotaxis [GO:1901624]; substantia nigra development [GO:0021762]; transcription initiation-coupled chromatin remodeling [GO:0045815] azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576] calcium ion binding [GO:0005509]; histone arginine deiminase activity [GO:0140794]; histone H3R26 arginine deiminase activity [GO:0140798]; nuclear estrogen receptor binding [GO:0030331]; protein homodimerization activity [GO:0042803]; protein-arginine deiminase activity [GO:0004668] 0.87139 0.063175 DGNLKDFPVK 0 0 0 0 0 0 0 0 0 0 9.04264 0 0 0 8.95536 0 9.0881 0 0 0 0 0 0 0 9.18881 9.01842 0 Q9Y2K1 ZBTB1_HUMAN Zinc finger and BTB domain-containing protein 1 ZBTB1 KIAA0997 Homo sapiens (Human) B cell differentiation [GO:0030183]; cellular response to UV [GO:0034644]; chromatin remodeling [GO:0006338]; DNA damage response [GO:0006974]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of pro-T cell differentiation [GO:2000176]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell mediated immunity [GO:0002711]; protein homooligomerization [GO:0051260]; regulation of cytokine production [GO:0001817]; regulation of immune system process [GO:0002682]; T cell differentiation in thymus [GO:0033077]; thymus development [GO:0048538]; translesion synthesis [GO:0019985] nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] DNA binding [GO:0003677]; K63-linked polyubiquitin modification-dependent protein binding [GO:0070530]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803] 0.96956 -3.4392 ERQLRLHNDMHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.52984 9.86391 9.45479 0 0 0 Q9Y2K2 SIK3_HUMAN Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein kinase QSK) SIK3 KIAA0999 QSK L19 Homo sapiens (Human) intracellular signal transduction [GO:0035556]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of TORC1 signaling [GO:1904263]; positive regulation of TORC2 signaling [GO:1904515]; protein phosphorylation [GO:0006468] cytoplasm [GO:0005737] ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; tau-protein kinase activity [GO:0050321] 0.88244 -0.088967 LSMEQICKHKWMK 0 0 0 0 0 0 10.4804 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y2K3 MYH15_HUMAN Myosin-15 (Myosin heavy chain 15) MYH15 KIAA1000 Homo sapiens (Human) cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; myofibril [GO:0030016]; myosin filament [GO:0032982]; myosin II complex [GO:0016460] actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; microfilament motor activity [GO:0000146] 0.96928 -3.4093 AEVAESQVNK 0 0 0 8.88579 10.4609 10.6173 0 0 0 9.92538 8.88634 9.16322 8.99367 0 0 8.28882 9.24055 0 0 0 10.9712 9.09835 0 0 0 0 0 Q9Y2K5 R3HD2_HUMAN R3H domain-containing protein 2 R3HDM2 KIAA1002 Homo sapiens (Human) nucleus [GO:0005634] RNA binding [GO:0003723] 0.95886 -1.7161 STKDVSEK 0 0 0 0 0 0 0 0 0 9.41511 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y2K6 UBP20_HUMAN Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.4.19.12) (Deubiquitinating enzyme 20) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (VHL-interacting deubiquitinating enzyme 2) (hVDU2) USP20 KIAA1003 LSFR3A VDU2 Homo sapiens (Human) antiviral innate immune response [GO:0140374]; endocytosis [GO:0006897]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; positive regulation of autophagy [GO:0010508]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; ubiquitin-dependent protein catabolic process [GO:0006511] centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; perinuclear region of cytoplasm [GO:0048471] cysteine-type deubiquitinase activity [GO:0004843]; cysteine-type endopeptidase activity [GO:0004197]; G protein-coupled receptor binding [GO:0001664]; zinc ion binding [GO:0008270] 0.96992 -4.3282 FRHEVMYSFK 0 0 0 9.50879 0 0 0 0 0 0 9.49759 9.87251 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y2K7 KDM2A_HUMAN Lysine-specific demethylase 2A (EC 1.14.11.27) (CXXC-type zinc finger protein 8) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina) (F-box/LRR-repeat protein 11) (JmjC domain-containing histone demethylation protein 1A) ([Histone-H3]-lysine-36 demethylase 1A) KDM2A CXXC8 FBL11 FBL7 FBXL11 JHDM1A KIAA1004 Homo sapiens (Human) circadian regulation of gene expression [GO:0032922]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of transcription by competitive promoter binding [GO:0010944]; protein demethylation [GO:0006482]; regulation of circadian rhythm [GO:0042752]; regulation of transcription by RNA polymerase II [GO:0006357] chromosome [GO:0005694]; nucleoplasm [GO:0005654] histone demethylase activity [GO:0032452]; histone H3K36 demethylase activity [GO:0051864]; histone H3K36me/H3K36me2 demethylase activity [GO:0140680]; transcription coregulator activity [GO:0003712]; unmethylated CpG binding [GO:0045322]; zinc ion binding [GO:0008270] 0.92438 -1.032 CYQEDSSEKAQK 0 0 0 9.82251 0 0 0 0 0 0 11.0997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y2K9 STB5L_HUMAN Syntaxin-binding protein 5-like (Lethal(2) giant larvae protein homolog 4) (Tomosyn-2) STXBP5L KIAA1006 LLGL4 Homo sapiens (Human) exocytosis [GO:0006887]; protein transport [GO:0015031]; regulation of exocytosis [GO:0017157]; regulation of protein secretion [GO:0050708] cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; SNARE complex [GO:0031201] GTPase activator activity [GO:0005096]; myosin II binding [GO:0045159]; syntaxin binding [GO:0019905] 0.88323 -0.26294 KQGYSNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.01112 0 0 0 0 0 0 0 0 0 8.58676 Q9Y2L1 RRP44_HUMAN Exosome complex exonuclease RRP44 (EC 3.1.13.-) (EC 3.1.26.-) (Protein DIS3 homolog) (Ribosomal RNA-processing protein 44) DIS3 KIAA1008 RRP44 Homo sapiens (Human) CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364] cytoplasmic exosome (RNase complex) [GO:0000177]; cytosol [GO:0005829]; exosome (RNase complex) [GO:0000178]; membrane [GO:0016020]; nuclear exosome (RNase complex) [GO:0000176]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 3'-5'-RNA exonuclease activity [GO:0000175]; endonuclease activity [GO:0004519]; guanyl-nucleotide exchange factor activity [GO:0005085]; RNA binding [GO:0003723] 0.94058 -1.3299 IEDTVFHVFDK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.40678 0 0 0 10.0542 0 0 Q9Y2L5 TPPC8_HUMAN Trafficking protein particle complex subunit 8 (Protein TRS85 homolog) TRAPPC8 KIAA1012 Homo sapiens (Human) COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; vesicle tethering [GO:0099022] cytoplasm [GO:0005737]; cytosol [GO:0005829]; TRAPP complex [GO:0030008]; TRAPPIII protein complex [GO:1990072] 0.91544 -0.81042 LSQEQHR 8.6462 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y2L6 FRM4B_HUMAN FERM domain-containing protein 4B (GRP1-binding protein GRSP1) FRMD4B GRSP1 KIAA1013 Homo sapiens (Human) establishment of epithelial cell polarity [GO:0090162] adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; extracellular space [GO:0005615]; ruffle [GO:0001726] 0.95413 -1.5329 EKILELK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2079 0 0 0 0 9.05053 8.96232 10.0417 0 0 0 0 Q9Y2L8 ZKSC5_HUMAN Zinc finger protein with KRAB and SCAN domains 5 (Zinc finger protein 95 homolog) (Zfp-95) ZKSCAN5 KIAA1015 ZFP95 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; zinc ion binding [GO:0008270] 0.8711 0.059269 AFGYSSDLIQHYR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.41794 0 0 0 0 Q9Y2M0 FAN1_HUMAN Fanconi-associated nuclease 1 (EC 3.1.21.-) (EC 3.1.4.1) (FANCD2/FANCI-associated nuclease 1) (hFAN1) (Myotubularin-related protein 15) FAN1 KIAA1018 MTMR15 Homo sapiens (Human) DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; interstrand cross-link repair [GO:0036297]; nucleotide-excision repair [GO:0006289] cytosol [GO:0005829]; intercellular bridge [GO:0045171]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] 5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; flap-structured DNA binding [GO:0070336]; magnesium ion binding [GO:0000287]; phosphodiesterase I activity [GO:0004528]; ubiquitin-dependent protein binding [GO:0140036] 0.574 0.47834 QQLVDAFLK 0 0 0 0 0 0 0 0 0 0 0 0 11.6509 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4515 Q9Y2M2 SSUH2_HUMAN Protein SSUH2 homolog (Protein ssu-2 homolog) SSUH2 C3orf32 FLS485 Homo sapiens (Human) odontogenesis [GO:0042476] cytoplasm [GO:0005737]; nucleus [GO:0005634] heat shock protein binding [GO:0031072]; unfolded protein binding [GO:0051082] 0.96282 -2.6661 CPSCCGAKRK 9.92932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2704 0 0 0 0 0 0 0 0 0 0 0 Q9Y2M5 KLH20_HUMAN Kelch-like protein 20 (Kelch-like ECT2-interacting protein) (Kelch-like protein X) KLHL20 KLEIP KLHLX Homo sapiens (Human) cytoskeleton organization [GO:0007010]; Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567]; response to interferon-alpha [GO:0035455] actin cytoskeleton [GO:0015629]; axon [GO:0030424]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; perinuclear region of cytoplasm [GO:0048471]; PML body [GO:0016605]; trans-Golgi network [GO:0005802] actin binding [GO:0003779]; type II interferon binding [GO:0019964]; ubiquitin-protein transferase activity [GO:0004842] 0.96381 -2.215 SDEECRDLVDEAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.212 0 0 9.97771 0 0 0 0 0 Q9Y2P5 S27A5_HUMAN "Long-chain fatty acid transport protein 5 (FATP-5) (Fatty acid transport protein 5) (Bile acid-CoA ligase) (BA-CoA ligase) (BAL) (Bile acyl-CoA synthetase) (BACS) (EC 6.2.1.7) (Cholate--CoA ligase) (Fatty-acid-coenzyme A ligase, very long-chain 3) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 5) (Very long-chain acyl-CoA synthetase homolog 2) (VLCS-H2) (VLCSH2) (EC 6.2.1.-) (Very long-chain acyl-CoA synthetase-related protein) (VLACS-related) (VLACSR)" SLC27A5 ACSB ACSVL6 FACVL3 FATP5 Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; bile acid biosynthetic process [GO:0006699]; establishment of localization in cell [GO:0051649]; ketone body biosynthetic process [GO:0046951]; long-chain fatty acid import across plasma membrane [GO:0015911]; triglyceride mobilization [GO:0006642]; very long-chain fatty acid metabolic process [GO:0000038] basal plasma membrane [GO:0009925]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; protein-containing complex [GO:0032991] ATP binding [GO:0005524]; cholate-CoA ligase activity [GO:0047747]; fatty acid transmembrane transporter activity [GO:0015245]; long-chain fatty acid transporter activity [GO:0005324]; long-chain fatty acid-CoA ligase activity [GO:0004467]; oxidoreductase activity [GO:0016491]; protein-containing complex binding [GO:0044877]; very long-chain fatty acid-CoA ligase activity [GO:0031957] 0.87089 0.055601 VLVVDPDLR 0 0 0 10.2434 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y2P7 ZN256_HUMAN Zinc finger protein 256 (Bone marrow zinc finger 3) (BMZF-3) ZNF256 BMZF3 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892] nucleoplasm [GO:0005654]; nucleus [GO:0005634] metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978] 0.91582 -0.77373 LYTDGACRK 0 0 0 0 0 0 0 0 0 0 0 10.3025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y2Q0 AT8A1_HUMAN Phospholipid-transporting ATPase IA (EC 7.6.2.1) (ATPase class I type 8A member 1) (Chromaffin granule ATPase II) (P4-ATPase flippase complex alpha subunit ATP8A1) ATP8A1 ATPIA Homo sapiens (Human) aminophospholipid translocation [GO:0140331]; learning [GO:0007612]; monoatomic ion transmembrane transport [GO:0034220]; phospholipid translocation [GO:0045332]; positive regulation of cell migration [GO:0030335]; positive regulation of phospholipid translocation [GO:0061092]; transport across blood-brain barrier [GO:0150104] azurophil granule membrane [GO:0035577]; chromaffin granule membrane [GO:0042584]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; organelle membrane [GO:0031090]; phospholipid-translocating ATPase complex [GO:1990531]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; synapse [GO:0045202]; trans-Golgi network [GO:0005802] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATPase-coupled intramembrane lipid transporter activity [GO:0140326]; ATPase-coupled monoatomic cation transmembrane transporter activity [GO:0019829]; magnesium ion binding [GO:0000287]; phosphatidylserine flippase activity [GO:0140346]; phosphatidylserine floppase activity [GO:0090556] 0.8175 0.22084 HCTTLGDALR 0 0 0 0 0 0 0 0 0 11.9029 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y2Q3 GSTK1_HUMAN Glutathione S-transferase kappa 1 (EC 2.5.1.18) (GST 13-13) (GST class-kappa) (GSTK1-1) (hGSTK1) (Glutathione S-transferase subunit 13) GSTK1 HDCMD47P Homo sapiens (Human) epithelial cell differentiation [GO:0030855]; glutathione metabolic process [GO:0006749] cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777] glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364] 0.92123 -1.1059 ELWMRVWSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6472 0 0 0 0 0 0 0 0 10.9508 0 0 Q9Y2R0 COA3_HUMAN "Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (Coiled-coil domain-containing protein 56) (Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 12 kDa)" COA3 CCDC56 MITRAC12 HSPC009 Homo sapiens (Human) mitochondrial cytochrome c oxidase assembly [GO:0033617]; positive regulation of mitochondrial translation [GO:0070131] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] 0.95199 -1.4515 IDPTREK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.71184 0 0 0 0 0 0 0 0 0 0 Q9Y2R2 PTN22_HUMAN Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP) (PEST-domain phosphatase) (PEP) PTPN22 PTPN8 Homo sapiens (Human) "autophagy [GO:0006914]; cellular response to muramyl dipeptide [GO:0071225]; lipid metabolic process [GO:0006629]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070433]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of T cell activation [GO:0050868]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of tumor necrosis factor production [GO:0032720]; peptidyl-tyrosine dephosphorylation [GO:0035335]; phosphoanandamide dephosphorylation [GO:0035644]; positive regulation of CD8-positive, alpha-beta T cell proliferation [GO:2000566]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of granzyme B production [GO:0071663]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of toll-like receptor 3 signaling pathway [GO:0034141]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type II interferon production [GO:0032729]; protein dephosphorylation [GO:0006470]; regulation of B cell receptor signaling pathway [GO:0050855]; regulation of innate immune response [GO:0045088]; regulation of natural killer cell proliferation [GO:0032817]; regulation of NIK/NF-kappaB signaling [GO:1901222]; response to lipopolysaccharide [GO:0032496]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]" cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471] kinase binding [GO:0019900]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase binding [GO:0031625] 0.8426 0.14822 TIYQFHYK 0 0 0 0 10.3372 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y2R4 DDX52_HUMAN Probable ATP-dependent RNA helicase DDX52 (EC 3.6.4.13) (ATP-dependent RNA helicase ROK1-like) (DEAD box protein 52) DDX52 ROK1 HUSSY-19 Homo sapiens (Human) maturation of SSU-rRNA [GO:0030490] membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] 0.92424 -1.0426 FDILVTTPNR 0 0 0 0 9.03348 0 0 0 12.7531 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y2R5 RT17_HUMAN "Small ribosomal subunit protein uS17m (28S ribosomal protein S17, mitochondrial) (MRP-S17) (S17mt)" MRPS17 RPMS17 HSPC011 Homo sapiens (Human) mitochondrial translation [GO:0032543]; translation [GO:0006412] mitochondrial inner membrane [GO:0005743]; mitochondrial small ribosomal subunit [GO:0005763] rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735] 0.88413 -0.29711 HVKHELAEIVFK 0 0 8.39699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y2R9 RT07_HUMAN "Small ribosomal subunit protein uS7m (28S ribosomal protein S7, mitochondrial) (MRP-S7) (S7mt) (bMRP-27a) (bMRP27a)" MRPS7 Homo sapiens (Human) mitochondrial translation [GO:0032543]; ribosomal small subunit assembly [GO:0000028]; translation [GO:0006412] mitochondrial inner membrane [GO:0005743]; mitochondrial small ribosomal subunit [GO:0005763]; ribosome [GO:0005840] mRNA binding [GO:0003729]; RNA binding [GO:0003723]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735] 0.89895 -0.59084 AVLQLPGLTQVRWSR 0 0 0 0 12.4011 0 0 0 0 0 9.17978 9.47573 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y2S7 PDIP2_HUMAN Polymerase delta-interacting protein 2 (38 kDa DNA polymerase delta interaction protein) (p38) POLDIP2 PDIP38 POLD4 HSPC017 Homo sapiens (Human) error-free translesion synthesis [GO:0070987]; mitochondrion morphogenesis [GO:0070584]; mitotic spindle assembly [GO:0090307]; negative regulation of macroautophagy [GO:0016242]; positive regulation of actin filament binding [GO:1904531]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of mitotic cytokinesis [GO:1903490]; positive regulation of Rho guanyl-nucleotide exchange factor activity [GO:2001108]; vascular associated smooth muscle cell proliferation [GO:1990874] cell-cell junction [GO:0005911]; midbody [GO:0030496]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; mitotic spindle [GO:0072686]; nucleus [GO:0005634]; plasma membrane [GO:0005886] DNA binding [GO:0003677] 0.96692 -2.3216 AACTARR 0 0 0 0 0 0 0 0 0 0 8.74359 0 9.15228 0 0 0 0 0 0 0 9.19835 0 0 0 0 0 0 Q9Y2T1 AXIN2_HUMAN Axin-2 (Axin-like protein) (Axil) (Axis inhibition protein 2) (Conductin) AXIN2 Homo sapiens (Human) aortic valve morphogenesis [GO:0003180]; bone mineralization [GO:0030282]; cell death [GO:0008219]; cell development [GO:0048468]; cellular response to dexamethasone stimulus [GO:0071549]; chondrocyte differentiation involved in endochondral bone morphogenesis [GO:0003413]; intramembranous ossification [GO:0001957]; maintenance of DNA repeat elements [GO:0043570]; mitral valve morphogenesis [GO:0003183]; mRNA stabilization [GO:0048255]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification [GO:2000054]; odontogenesis [GO:0042476]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of cell death [GO:0010942]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein localization [GO:0008104]; regulation of centromeric sister chromatid cohesion [GO:0070602]; regulation of chondrocyte development [GO:0061181]; regulation of extracellular matrix organization [GO:1903053]; regulation of mismatch repair [GO:0032423]; secondary heart field specification [GO:0003139]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; Wnt signaling pathway [GO:0016055] beta-catenin destruction complex [GO:0030877]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886] beta-catenin binding [GO:0008013]; enzyme binding [GO:0019899]; I-SMAD binding [GO:0070411]; molecular adaptor activity [GO:0060090]; protein kinase binding [GO:0019901]; ubiquitin protein ligase binding [GO:0031625] 0.96338 -2.1382 AYPLESAR 0 0 0 0 0 0 0 11.0174 0 0 0 10.3157 0 0 9.2677 0 0 0 0 0 0 0 9.68697 0 0 0 0 Q9Y2T2 AP3M1_HUMAN AP-3 complex subunit mu-1 (AP-3 adaptor complex mu3A subunit) (Adaptor-related protein complex 3 subunit mu-1) (Mu-adaptin 3A) (Mu3A-adaptin) AP3M1 Homo sapiens (Human) "anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; clathrin-coated vesicle cargo loading, AP-3-mediated [GO:0035654]; endocytosis [GO:0006897]; intracellular transport [GO:0046907]; melanosome assembly [GO:1903232]; platelet dense granule organization [GO:0060155]; protein targeting to lysosome [GO:0006622]; vesicle-mediated transport [GO:0016192]" AP-3 adaptor complex [GO:0030123]; axon cytoplasm [GO:1904115]; clathrin adaptor complex [GO:0030131]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; early endosome [GO:0005769]; Golgi apparatus [GO:0005794]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764] small GTPase binding [GO:0031267] 0.71184 0.36745 VLSFIPPDGNFR 0 0 0 0 0 0 0 0 0 0 0 9.77891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y2T3 GUAD_HUMAN Guanine deaminase (Guanase) (Guanine aminase) (EC 3.5.4.3) (Guanine aminohydrolase) (GAH) (p51-nedasin) GDA KIAA1258 Homo sapiens (Human) allantoin metabolic process [GO:0000255]; amide catabolic process [GO:0043605]; deoxyguanosine catabolic process [GO:0006161]; dGMP catabolic process [GO:0046055]; GMP catabolic process [GO:0046038]; guanine catabolic process [GO:0006147]; guanine metabolic process [GO:0046098]; nervous system development [GO:0007399]; nucleobase-containing compound metabolic process [GO:0006139] cytosol [GO:0005829] guanine deaminase activity [GO:0008892]; zinc ion binding [GO:0008270] 0.91394 -0.79956 IVFLEEASQQEKLAK 0 10.9862 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y2T5 GPR52_HUMAN G-protein coupled receptor 52 GPR52 Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; locomotory behavior [GO:0007626]; response to xenobiotic stimulus [GO:0009410] plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930] 0.40114 0.70313 LSETMCTSCMCVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.75729 0 0 0 0 0 Q9Y2T7 YBOX2_HUMAN Y-box-binding protein 2 (Contrin) (DNA-binding protein C) (Dbpc) (Germ cell-specific Y-box-binding protein) (MSY2 homolog) YBX2 CSDA3 MSY2 Homo sapiens (Human) oocyte development [GO:0048599]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of gene expression [GO:0010468]; spermatogenesis [GO:0007283]; transcription by RNA polymerase II [GO:0006366]; translational attenuation [GO:0009386] cytoplasm [GO:0005737]; nucleus [GO:0005634] DNA binding [GO:0003677]; nucleic acid binding [GO:0003676]; RNA binding [GO:0003723] 0 4.5833 AEDSGQRPR 0 0 0 0 0 0 0 0 8.68398 0 0 0 8.55493 0 0 9.10247 8.9107 9.07967 0 0 0 0 0 0 0 10.3234 0 Q9Y2U5 M3K2_HUMAN Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2) MAP3K2 MAPKKK2 MEKK2 Homo sapiens (Human) cellular response to mechanical stimulus [GO:0071260]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654] ATP binding [GO:0005524]; MAP kinase kinase kinase activity [GO:0004709]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.91668 -0.76593 IVQYYGCLR 0 9.79316 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y2U8 MAN1_HUMAN Inner nuclear membrane protein Man1 (LEM domain-containing protein 3) LEMD3 MAN1 Homo sapiens (Human) negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512] membrane [GO:0016020]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965] DNA binding [GO:0003677]; U1 snRNP binding [GO:1990446] 0.8902 -0.47003 LDRYHHR 0 0 0 0 0 0 0 0 0 0 9.49723 9.96015 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y2U9 KLDC2_HUMAN Kelch domain-containing protein 2 (Hepatocellular carcinoma-associated antigen 33) (Host cell factor homolog LCP) (Host cell factor-like protein 1) (HCLP-1) KLHDC2 HCA33 Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] Cul2-RING ubiquitin ligase complex [GO:0031462]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ubiquitin ligase-substrate adaptor activity [GO:1990756] 0.58557 0.46593 HLLHSVNQRFGSNNTSGS 0 0 11.2309 10.0897 0 0 0 0 0 0 0 0 10.0102 0 0 0 10.8886 11.1331 0 0 10.3453 0 0 0 0 0 0 Q9Y2V0 CDIN1_HUMAN CDAN1-interacting nuclease 1 (Protein HH114) CDIN1 C15orf41 Homo sapiens (Human) erythrocyte differentiation [GO:0030218] cytoplasm [GO:0005737]; nucleus [GO:0005634] 0.55774 0.54865 ACFPTNIVTLCHSIA 10.6015 0 0 0 0 0 9.66044 0 0 0 0 0 0 0 0 9.97771 0 0 0 0 0 0 0 0 0 0 0 Q9Y2V3 RX_HUMAN Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein) RAX RX Homo sapiens (Human) camera-type eye development [GO:0043010]; hypothalamus development [GO:0021854]; limb development [GO:0060173]; pattern specification process [GO:0007389]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; visual perception [GO:0007601] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.50821 0.60675 LGARPACPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.13093 0 0 0 0 0 Q9Y2V7 COG6_HUMAN Conserved oligomeric Golgi complex subunit 6 (COG complex subunit 6) (Component of oligomeric Golgi complex 6) COG6 KIAA1134 Homo sapiens (Human) "glycosylation [GO:0070085]; Golgi organization [GO:0007030]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]; retrograde transport, vesicle recycling within Golgi [GO:0000301]" Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; trans-Golgi network membrane [GO:0032588] 0.92564 -0.98289 AAMVQFDR 0 0 0 0 0 0 0 0 0 0 10.5371 0 0 0 0 0 0 0 0 0 0 9.21043 0 0 0 0 0 Q9Y2W1 TR150_HUMAN Thyroid hormone receptor-associated protein 3 (BCLAF1 and THRAP3 family member 2) (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150) THRAP3 BCLAF2 TRAP150 Homo sapiens (Human) "circadian rhythm [GO:0007623]; mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; nuclear-transcribed mRNA catabolic process [GO:0000956]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]" extracellular exosome [GO:0070062]; mediator complex [GO:0016592]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; DNA binding [GO:0003677]; nuclear receptor coactivator activity [GO:0030374]; nuclear thyroid hormone receptor binding [GO:0046966]; nuclear vitamin D receptor binding [GO:0042809]; phosphoprotein binding [GO:0051219]; RNA binding [GO:0003723]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712] 0.96947 -4.7187 EESTTGFDK 0 0 0 0 11.5451 0 0 0 0 0 0 0 0 9.66224 0 0 0 0 0 0 9.25361 0 0 0 0 0 0 Q9Y2W7 CSEN_HUMAN Calsenilin (A-type potassium channel modulatory protein 3) (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (KChIP3) KCNIP3 CSEN DREAM KCHIP3 Homo sapiens (Human) apoptotic process [GO:0006915]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transmembrane transport [GO:1901379]; signal transduction [GO:0007165] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076] "calcium ion binding [GO:0005509]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; potassium channel activity [GO:0005267]; potassium channel regulator activity [GO:0015459]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; voltage-gated monoatomic ion channel activity [GO:0005244]" 0.9553 -1.5607 QPAKEVTK 0 0 0 10.1076 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y2X0 MED16_HUMAN Mediator of RNA polymerase II transcription subunit 16 (Mediator complex subunit 16) (Thyroid hormone receptor-associated protein 5) (Thyroid hormone receptor-associated protein complex 95 kDa component) (Trap95) (Vitamin D3 receptor-interacting protein complex 92 kDa component) (DRIP92) MED16 DRIP92 THRAP5 Homo sapiens (Human) positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366] core mediator complex [GO:0070847]; mediator complex [GO:0016592]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] nuclear thyroid hormone receptor binding [GO:0046966]; nuclear vitamin D receptor binding [GO:0042809]; transcription coactivator activity [GO:0003713] 0.16476 0.97948 DGTSLGMLR 0 0 0 0 0 0 0 0 0 0 11.4835 0 0 10.5482 0 0 0 0 0 0 0 0 0 0 0 0 10.1741 Q9Y2X3 NOP58_HUMAN Nucleolar protein 58 (Nucleolar protein 5) NOP58 NOL5 NOP5 HSPC120 Homo sapiens (Human) ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364]; snoRNA localization [GO:0048254] box C/D RNP complex [GO:0031428]; Cajal body [GO:0015030]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; pre-snoRNP complex [GO:0070761]; small-subunit processome [GO:0032040]; sno(s)RNA-containing ribonucleoprotein complex [GO:0005732] ATPase binding [GO:0051117]; RNA binding [GO:0003723]; snoRNA binding [GO:0030515]; TFIID-class transcription factor complex binding [GO:0001094] 0.94077 -1.3289 IISDNLTYCK 0 0 0 0 0 0 0 0 0 0 0 0 0 8.66306 0 0 0 0 0 0 9.34716 0 0 0 10.1794 0 9.76247 Q9Y2X7 GIT1_HUMAN ARF GTPase-activating protein GIT1 (ARF GAP GIT1) (Cool-associated and tyrosine-phosphorylated protein 1) (CAT-1) (CAT1) (G protein-coupled receptor kinase-interactor 1) (GRK-interacting protein 1) (p95-APP1) GIT1 Homo sapiens (Human) brain development [GO:0007420]; cell redox homeostasis [GO:0045454]; cellular response to lipopolysaccharide [GO:0071222]; ephrin receptor signaling pathway [GO:0048013]; intramembranous ossification [GO:0001957]; locomotory behavior [GO:0007626]; motor learning [GO:0061743]; negative regulation of glycolytic process [GO:0045820]; negative regulation of inflammatory response to wounding [GO:0106015]; negative regulation of interleukin-1 beta production [GO:0032691]; neuron development [GO:0048666]; positive regulation of microtubule nucleation [GO:0090063]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of ARF protein signal transduction [GO:0032012]; regulation of cytokinesis [GO:0032465]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; regulation of synaptic vesicle exocytosis [GO:2000300]; synaptic vesicle recycling [GO:0036465] calyx of Held [GO:0044305]; centrosome [GO:0005813]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; membrane [GO:0016020]; mitochondrion [GO:0005739]; mitotic spindle pole [GO:0097431]; neuron projection [GO:0043005]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; synapse [GO:0045202] gamma-tubulin binding [GO:0043015]; GTPase activator activity [GO:0005096]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; small GTPase binding [GO:0031267] 0.92116 -1.1049 ALATSEAK 0 0 0 0 0 0 0 0 0 0 12.3633 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5079 0 Q9Y2X9 ZN281_HUMAN Zinc finger protein 281 (GC-box-binding zinc finger protein 1) (Transcription factor ZBP-99) (Zinc finger DNA-binding protein 99) ZNF281 GZP1 ZBP99 Homo sapiens (Human) embryonic body morphogenesis [GO:0010172]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription [GO:0006355]; stem cell differentiation [GO:0048863] nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription cis-regulatory region binding [GO:0000976]" 0.91516 -0.81048 RTCGEVIVK 0 0 0 0 0 0 0 8.94483 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y2Y0 AR2BP_HUMAN ADP-ribosylation factor-like protein 2-binding protein (ARF-like 2-binding protein) (ARL2-binding protein) (Binder of ARF2 protein 1) ARL2BP BART BART1 Homo sapiens (Human) maintenance of protein location in nucleus [GO:0051457]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; signal transduction [GO:0007165] centrosome [GO:0005813]; cilium [GO:0005929]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; nucleoplasm [GO:0005654]; spindle [GO:0005819] GTPase regulator activity [GO:0030695]; transcription coactivator activity [GO:0003713] 0.95377 -1.525 EMFLDYRAEK 0 0 0 0 0 0 0 0 8.94808 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y2Y9 KLF13_HUMAN Krueppel-like factor 13 (Basic transcription element-binding protein 3) (BTE-binding protein 3) (Novel Sp1-like zinc finger transcription factor 1) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Transcription factor BTEB3) (Transcription factor NSLP1) KLF13 BTEB3 NSLP1 Homo sapiens (Human) negative regulation of cell population proliferation [GO:0008285]; negative regulation of erythrocyte differentiation [GO:0045647]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.933 -1.2788 FSCPICEKRFMR 0 0 0 0 0 0 0 0 0 0 0 0 10.2234 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y2Z0 SGT1_HUMAN Protein SGT1 homolog (Protein 40-6-3) (Sgt1) (Suppressor of G2 allele of SKP1 homolog) SUGT1 Homo sapiens (Human) mitotic cell cycle [GO:0000278]; regulation of protein stability [GO:0031647] cytosol [GO:0005829]; kinetochore [GO:0000776]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151] protein-folding chaperone binding [GO:0051087] 0.0059701 2.4593 AAAAAGTATSQR 0 8.65517 0 0 0 0 10.6046 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y2Z2 MTO1_HUMAN "Protein MTO1 homolog, mitochondrial" MTO1 CGI-02 Homo sapiens (Human) tRNA methylation [GO:0030488]; tRNA wobble uridine modification [GO:0002098] cytosol [GO:0005829]; mitochondrion [GO:0005739] flavin adenine dinucleotide binding [GO:0050660]; RNA binding [GO:0003723] 0.96012 -1.8936 DVSLSHEVR 0 0 0 0 8.39245 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.73207 0 0 0 0 0 10.7745 Q9Y2Z4 SYYM_HUMAN "Tyrosine--tRNA ligase, mitochondrial (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS)" YARS2 CGI-04 Homo sapiens (Human) mitochondrial tyrosyl-tRNA aminoacylation [GO:0070184]; translation [GO:0006412]; tRNA aminoacylation [GO:0043039] cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear body [GO:0016604] ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; tRNA binding [GO:0000049]; tyrosine binding [GO:0072545]; tyrosine-tRNA ligase activity [GO:0004831] 0.95306 -1.4796 QPDDSVERYLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4887 0 0 0 0 0 0 0 0 0 0 Q9Y2Z9 COQ6_HUMAN "Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial (EC 1.14.13.-) (Coenzyme Q10 monooxygenase 6)" COQ6 CGI-10 Homo sapiens (Human) ubiquinone biosynthetic process [GO:0006744] cell projection [GO:0042995]; extrinsic component of mitochondrial inner membrane [GO:0031314]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ubiquinone biosynthesis complex [GO:0110142] "2-octaprenyl-6-methoxyphenol hydroxylase activity [GO:0008681]; 4-hydroxy-3-all-trans-hexaprenylbenzoate oxygenase activity [GO:0106364]; FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]" 0.2219 0.87926 ILLLEAGPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3214 0 11.1584 11.0373 0 0 0 0 Q9Y305 ACOT9_HUMAN "Acyl-coenzyme A thioesterase 9, mitochondrial (Acyl-CoA thioesterase 9) (EC 3.1.2.-) (Acyl-CoA thioester hydrolase 9)" ACOT9 CGI-16 Homo sapiens (Human) acyl-CoA metabolic process [GO:0006637] mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739] acetyl-CoA hydrolase activity [GO:0003986]; acyl-CoA hydrolase activity [GO:0047617]; carboxylic ester hydrolase activity [GO:0052689]; palmitoyl-CoA hydrolase activity [GO:0016290] 0.92434 -1.0639 DHVKAMEER 0 8.72055 0 0 0 9.04971 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y312 AAR2_HUMAN Protein AAR2 homolog (AAR2 splicing factor homolog) AAR2 C20orf4 CGI-23 PRO0225 Homo sapiens (Human) spliceosomal tri-snRNP complex assembly [GO:0000244] spliceosomal complex [GO:0005681]; U5 snRNP [GO:0005682] 0.13167 1.0628 LLNLLCR 11.1085 10.8814 10.4477 0 0 0 0 0 10.4341 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.1954 0 0 Q9Y324 FCF1_HUMAN rRNA-processing protein FCF1 homolog FCF1 C14orf111 CGI-35 Homo sapiens (Human) "endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000480]; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; ribosomal small subunit biogenesis [GO:0042274]" nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040] RNA binding [GO:0003723] 0.95814 -1.6892 FERLPCTHK 0 0 0 0 0 0 0 0 0 0 11.3689 0 0 0 0 0 0 0 11.3805 0 0 0 0 0 0 0 0 Q9Y333 LSM2_HUMAN U6 snRNA-associated Sm-like protein LSm2 (Protein G7b) (Small nuclear ribonuclear protein D homolog) (snRNP core Sm-like protein Sm-x5) LSM2 C6orf28 G7B Homo sapiens (Human) "mRNA catabolic process [GO:0006402]; mRNA splicing, via spliceosome [GO:0000398]; spliceosomal tri-snRNP complex assembly [GO:0000244]" catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Lsm1-7-Pat1 complex [GO:1990726]; Lsm2-8 complex [GO:0120115]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; precatalytic spliceosome [GO:0071011]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U6 snRNP [GO:0005688] RNA binding [GO:0003723]; small GTPase binding [GO:0031267]; U6 snRNA binding [GO:0017070] 0.7987 0.23965 LTDISVTDPEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.28949 0 0 0 0 0 Q9Y345 SC6A5_HUMAN Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5) SLC6A5 GLYT2 NET1 Homo sapiens (Human) "chemical synaptic transmission [GO:0007268]; glycine import across plasma membrane [GO:1903804]; neurotransmitter transport [GO:0006836]; sodium ion transmembrane transport [GO:0035725]; synaptic transmission, glycinergic [GO:0060012]" dense core granule [GO:0031045]; endosome [GO:0005768]; glycinergic synapse [GO:0098690]; membrane [GO:0016020]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734] glycine:sodium symporter activity [GO:0015375]; metal ion binding [GO:0046872] 0.95217 -1.4474 GPEGDANVSVGK 0 0 0 0 0 0 0 0 0 10.2949 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y371 SHLB1_HUMAN Endophilin-B1 (Bax-interacting factor 1) (Bif-1) (SH3 domain-containing GRB2-like protein B1) SH3GLB1 KIAA0491 CGI-61 Homo sapiens (Human) apoptotic process [GO:0006915]; autophagic cell death [GO:0048102]; autophagy [GO:0006914]; cellular response to amino acid starvation [GO:0034198]; cellular response to glucose starvation [GO:0042149]; membrane fission [GO:0090148]; membrane organization [GO:0061024]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of autophagy [GO:0010508]; positive regulation of membrane tubulation [GO:1903527]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein-containing complex assembly [GO:0031334]; protein localization to vacuolar membrane [GO:1903778]; receptor catabolic process [GO:0032801]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241]; regulation of protein stability [GO:0031647] autophagosome membrane [GO:0000421]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrial outer membrane [GO:0005741]; protein-containing complex [GO:0032991] cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803] 0.8823 -0.10305 AECTKIWTEKIMK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.82435 Q9Y383 LC7L2_HUMAN Putative RNA-binding protein Luc7-like 2 LUC7L2 CGI-59 CGI-74 Homo sapiens (Human) mRNA splice site selection [GO:0006376] nuclear speck [GO:0016607]; U1 snRNP [GO:0005685]; U2-type prespliceosome [GO:0071004] enzyme binding [GO:0019899]; mRNA binding [GO:0003729]; RNA binding [GO:0003723] 0.89676 -0.53224 IKFSDDRVCK 0 0 10.409 0 0 0 0 0 0 15.2815 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y388 RBMX2_HUMAN "RNA-binding motif protein, X-linked 2" RBMX2 CGI-79 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; U2-type prespliceosome assembly [GO:1903241]" endoplasmic reticulum [GO:0005783]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; precatalytic spliceosome [GO:0071011]; spliceosomal complex [GO:0005681]; U2 snRNP [GO:0005686]; U2-type precatalytic spliceosome [GO:0071005] RNA binding [GO:0003723] 0.92178 -1.1324 TIRVDHVSNYR 0 0 0 0 0 0 0 0 0 0 0 0 0 8.88127 0 0 0 0 0 10.4372 8.97522 0 0 0 0 0 0 Q9Y3A0 COQ4_HUMAN "Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial (Coenzyme Q biosynthesis protein 4 homolog)" COQ4 CGI-92 Homo sapiens (Human) ubiquinone biosynthetic process [GO:0006744] extrinsic component of mitochondrial inner membrane [GO:0031314]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; ubiquinone biosynthesis complex [GO:0110142] 0.95141 -1.3988 DQMRRDPEGAQILQERPR 0 9.95201 0 0 0 0 0 0 9.15649 0 0 0 0 0 9.24053 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y3A3 PHOCN_HUMAN MOB-like protein phocein (2C4D) (Class II mMOB1) (Mob1 homolog 3) (Mob3) (Mps one binder kinase activator-like 3) (Preimplantation protein 3) MOB4 MOB3 MOBKL3 PHOCN PREI3 CGI-95 Homo sapiens (Human) cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471] kinase binding [GO:0019900]; metal ion binding [GO:0046872] 0.87127 0.037541 IFSHAYFHHR 0 0 0 0 9.14126 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y3B7 RM11_HUMAN "Large ribosomal subunit protein uL11m (39S ribosomal protein L11, mitochondrial) (L11mt) (MRP-L11)" MRPL11 CGI-113 Homo sapiens (Human) mitochondrial translation [GO:0032543]; translation [GO:0006412] mitochondrial inner membrane [GO:0005743]; mitochondrial large ribosomal subunit [GO:0005762]; mitochondrial ribosome [GO:0005761]; mitochondrion [GO:0005739] large ribosomal subunit rRNA binding [GO:0070180]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.87791 -0.0028308 GVSINQFCK 0 0 0 0 0 0 0 0 0 11.211 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y3B8 ORN_HUMAN "Oligoribonuclease, mitochondrial (EC 3.1.15.-) (RNA exonuclease 2 homolog) (Small fragment nuclease)" REXO2 SFN SMFN CGI-114 Homo sapiens (Human) nucleobase-containing compound metabolic process [GO:0006139]; nucleotide metabolic process [GO:0009117] cytoplasm [GO:0005737]; focal adhesion [GO:0005925]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634] 3'-5' exonuclease activity [GO:0008408]; 3'-5'-DNA exonuclease activity [GO:0008296]; 3'-5'-RNA exonuclease activity [GO:0000175]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676] 0.96373 -2.2162 GVGGSHGRFGAR 0 0 0 0 0 0 0 0 0 0 12.8702 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y3B9 RRP15_HUMAN RRP15-like protein (Ribosomal RNA-processing protein 15) RRP15 KIAA0507 CGI-115 Homo sapiens (Human) maturation of 5.8S rRNA [GO:0000460]; maturation of LSU-rRNA [GO:0000470] "preribosome, large subunit precursor [GO:0030687]" 0.89032 -0.49196 GVVQLFNAVQKHQK 0 0 0 0 0 0 0 0 0 0 0 0 0 8.75014 0 0 0 0 9.70745 0 9.38513 0 9.73515 0 0 0 0 Q9Y3C0 WASC3_HUMAN WASH complex subunit 3 (Coiled-coil domain-containing protein 53) WASHC3 AD-016 CCDC53 CGI-116 x0009 Homo sapiens (Human) actin filament polymerization [GO:0030041]; endosomal transport [GO:0016197]; exocytosis [GO:0006887]; protein transport [GO:0015031]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315] early endosome membrane [GO:0031901]; WASH complex [GO:0071203] 0.91508 -0.81471 VPAIQQKR 0 0 0 0 0 0 0 0 10.0629 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y3C1 NOP16_HUMAN Nucleolar protein 16 (HBV pre-S2 trans-regulated protein 3) NOP16 CGI-117 HSPC111 Homo sapiens (Human) ribosomal large subunit biogenesis [GO:0042273] intracellular membrane-bounded organelle [GO:0043231]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] RNA binding [GO:0003723] 0.90275 -0.70106 LNRNARR 0 10.6491 0 0 0 0 0 0 0 0 0 10.0577 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y3C6 PPIL1_HUMAN Peptidyl-prolyl cis-trans isomerase-like 1 (PPIase) (EC 5.2.1.8) (Rotamase PPIL1) PPIL1 CYPL1 CGI-124 UNQ2425/PRO4984 Homo sapiens (Human) "embryonic brain development [GO:1990403]; mRNA splicing, via spliceosome [GO:0000398]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]" catalytic step 2 spliceosome [GO:0071013]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type catalytic step 2 spliceosome [GO:0071007] cyclosporin A binding [GO:0016018]; disordered domain specific binding [GO:0097718]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755] 0.95489 -1.5219 TCKNFAELAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.85689 0 0 0 0 Q9Y3D3 RT16_HUMAN "Small ribosomal subunit protein bS16m (28S ribosomal protein S16, mitochondrial) (MRP-S16) (S16mt)" MRPS16 RPMS16 CGI-132 Homo sapiens (Human) mitochondrial translation [GO:0032543]; translation [GO:0006412] cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial small ribosomal subunit [GO:0005763]; mitochondrion [GO:0005739] structural constituent of ribosome [GO:0003735] 0.89909 -0.57115 IVAAHNKCPR 0 0 0 0 0 0 0 0 0 0 15.3086 15.2481 12.73 0 12.8245 0 13.2292 13.2781 0 0 0 0 0 0 0 0 0 Q9Y3D6 FIS1_HUMAN Mitochondrial fission 1 protein (FIS1 homolog) (hFis1) (Tetratricopeptide repeat protein 11) (TPR repeat protein 11) FIS1 TTC11 CGI-135 Homo sapiens (Human) autophagy of mitochondrion [GO:0000422]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; mitochondrial fission [GO:0000266]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrial fusion [GO:0008053]; mitochondrion morphogenesis [GO:0070584]; negative regulation of ATP metabolic process [GO:1903579]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; negative regulation of fatty acid transport [GO:2000192]; peroxisome fission [GO:0016559]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of protein targeting to membrane [GO:0090314]; protein targeting to mitochondrion [GO:0006626]; regulation of mitochondrion organization [GO:0010821]; release of cytochrome c from mitochondria [GO:0001836] cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991] identical protein binding [GO:0042802]; lipid binding [GO:0008289]; molecular adaptor activity [GO:0060090] 0.96417 -2.4023 AAGSVSK 0 0 0 0 0 0 12.2009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2628 0 0 0 Q9Y3D7 TIM16_HUMAN Mitochondrial import inner membrane translocase subunit TIM16 (Mitochondria-associated granulocyte macrophage CSF-signaling molecule) (Presequence translocated-associated motor subunit PAM16) PAM16 MAGMAS TIM16 TIMM16 CGI-136 Homo sapiens (Human) intracellular protein transport [GO:0006886]; negative regulation of ATP-dependent activity [GO:0032780]; ossification [GO:0001503]; protein import into mitochondrial matrix [GO:0030150] "mitochondrial matrix [GO:0005759]; PAM complex, Tim23 associated import motor [GO:0001405]; protein-containing complex [GO:0032991]; TIM23 mitochondrial import inner membrane translocase complex [GO:0005744]" 0.84621 0.17435 LSPEEVQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.8463 0 0 0 0 0 0 Q9Y3E0 GOT1B_HUMAN Vesicle transport protein GOT1B (Germ cell tumor 2) (Golgi transport 1 homolog B) (Putative NF-kappa-B-activating protein 470) (hGOT1a) GOLT1B GCT2 GOT1A CGI-141 HDCMA39P UNQ432/PRO793 Homo sapiens (Human) "endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]" cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; protein-containing complex [GO:0032991] 0.13835 1.0487 MISLTDTQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.03039 0 0 0 0 0 0 Q9Y3E2 BOLA1_HUMAN BolA-like protein 1 (hBolA) BOLA1 CGI-143 Homo sapiens (Human) cell redox homeostasis [GO:0045454]; iron-sulfur cluster assembly [GO:0016226] iron-sulfur cluster assembly complex [GO:1990229]; mitochondrion [GO:0005739] 0.78571 0.25902 LVLGLVSMAGR 0 0 0 0 0 0 0 9.75216 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y3F4 STRAP_HUMAN Serine-threonine kinase receptor-associated protein (MAP activator with WD repeats) (UNR-interacting protein) (WD-40 repeat protein PT-WD) STRAP MAWD UNRIP Homo sapiens (Human) "alternative mRNA splicing, via spliceosome [GO:0000380]; maintenance of gastrointestinal epithelium [GO:0030277]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron differentiation [GO:0030182]; spliceosomal snRNP assembly [GO:0000387]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; SMN complex [GO:0032797]; SMN-Sm protein complex [GO:0034719] mRNA binding [GO:0003729]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; U2 snRNP binding [GO:1990447] 0.010178 1.9521 AATAAADFTAK 0 0 0 0 0 0 0 0 0 0 9.8467 9.43875 0 0 0 0 0 0 0 10.4177 0 0 0 0 0 0 0 Q9Y3I0 RTCB_HUMAN RNA-splicing ligase RtcB homolog (EC 6.5.1.8) (3'-phosphate/5'-hydroxy nucleic acid ligase) RTCB C22orf28 HSPC117 Homo sapiens (Human) "in utero embryonic development [GO:0001701]; placenta development [GO:0001890]; tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate [GO:0000971]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tRNA-splicing ligase complex [GO:0072669] GTP binding [GO:0005525]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA ligase (ATP) activity [GO:0003972]; vinculin binding [GO:0017166] 0.082852 1.235 LMFEELR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3363 0 9.83651 0 0 0 0 0 0 0 0 Q9Y3I1 FBX7_HUMAN F-box only protein 7 FBXO7 FBX7 Homo sapiens (Human) autophagy of mitochondrion [GO:0000422]; lymphocyte differentiation [GO:0030098]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of lymphocyte differentiation [GO:0045620]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; positive regulation of autophagy of mitochondrion [GO:1903599]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein targeting to mitochondrion [GO:0006626]; protein ubiquitination [GO:0016567]; regulation of locomotion [GO:0040012]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; ubiquitin-dependent protein catabolic process [GO:0006511] classical Lewy body [GO:0097414]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glial cytoplasmic inclusion [GO:0097409]; Lewy body core [GO:1990037]; Lewy body corona [GO:1990038]; Lewy neurite [GO:0097462]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; SCF ubiquitin ligase complex [GO:0019005]; ubiquitin ligase complex [GO:0000151] protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; ubiquitin binding [GO:0043130]; ubiquitin ligase-substrate adaptor activity [GO:1990756]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842] 0.92274 -1.0746 DNTVRVQDTDWK 0 0 0 0 9.52615 0 0 0 0 0 0 0 0 10.6233 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y3L3 3BP1_HUMAN SH3 domain-binding protein 1 SH3BP1 Homo sapiens (Human) "actin filament organization [GO:0007015]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; establishment of epithelial cell apical/basal polarity [GO:0045198]; filopodium assembly [GO:0046847]; negative regulation of small GTPase mediated signal transduction [GO:0051058]; phagocytosis, engulfment [GO:0006911]; positive regulation of GTPase activity [GO:0043547]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin filament depolymerization [GO:0030834]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of Rac protein signal transduction [GO:0035020]; regulation of small GTPase mediated signal transduction [GO:0051056]; ruffle assembly [GO:0097178]; semaphorin-plexin signaling pathway [GO:0071526]" adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; lamellipodium [GO:0030027]; nucleus [GO:0005634]; phagocytic cup [GO:0001891] GTPase activator activity [GO:0005096]; semaphorin receptor binding [GO:0030215]; SH3 domain binding [GO:0017124] 0.8123 0.22377 DEYLADLYHFVTKEDSYANYFIR 0 0 0 0 0 0 0 0 8.26144 0 0 0 0 0 0 0 0 9.47822 9.1631 9.31915 0 0 0 0 0 0 0 Q9Y3M8 STA13_HUMAN StAR-related lipid transfer protein 13 (46H23.2) (Deleted in liver cancer 2 protein) (DLC-2) (Rho GTPase-activating protein) (START domain-containing protein 13) (StARD13) STARD13 DLC2 GT650 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] cytosol [GO:0005829]; lipid droplet [GO:0005811]; mitochondrial membrane [GO:0031966] GTPase activator activity [GO:0005096]; lipid binding [GO:0008289] 0.96816 -3.6809 DLPEPLFTNK 0 0 0 0 9.03304 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.39281 0 10.7591 0 0 0 11.6199 0 Q9Y3M9 ZN337_HUMAN Zinc finger protein 337 ZNF337 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]" 0.93285 -1.2589 CAERGQDFSRK 0 0 0 0 0 0 0 0 0 0 0 9.62832 9.72173 10.1111 0 0 0 9.73892 9.09434 0 0 0 0 9.2087 0 0 0 Q9Y3P9 RBGP1_HUMAN Rab GTPase-activating protein 1 (GAP and centrosome-associated protein) (Rab6 GTPase-activating protein GAPCenA) RABGAP1 HSPC094 Homo sapiens (Human) cell cycle [GO:0007049]; regulation of GTPase activity [GO:0043087] centrosome [GO:0005813]; cytosol [GO:0005829]; microtubule associated complex [GO:0005875] GTPase activator activity [GO:0005096]; small GTPase binding [GO:0031267]; tubulin binding [GO:0015631] 0.041126 1.4887 KNNTDTLYEVVCLESESERER 11.311 10.6519 0 0 0 0 8.77288 9.6209 9.28411 0 9.13098 9.62126 0 0 0 0 0 9.66212 0 0 0 10.502 0 0 0 0 8.52857 Q9Y3Q0 NALD2_HUMAN N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II) NAALAD2 Homo sapiens (Human) proteolysis [GO:0006508] membrane [GO:0016020]; plasma membrane [GO:0005886] carboxypeptidase activity [GO:0004180]; dipeptidase activity [GO:0016805]; dipeptidyl-peptidase activity [GO:0008239]; metal ion binding [GO:0046872]; metallocarboxypeptidase activity [GO:0004181]; serine-type peptidase activity [GO:0008236] 0.9693 -3.5619 FYDPTFKK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14.9052 8.35971 0 0 0 0 0 0 0 Q9Y3Q4 HCN4_HUMAN Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 HCN4 Homo sapiens (Human) blood circulation [GO:0008015]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; membrane depolarization during cardiac muscle cell action potential [GO:0086012]; membrane depolarization during SA node cell action potential [GO:0086046]; monoatomic cation transport [GO:0006812]; muscle contraction [GO:0006936]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; regulation of cardiac muscle cell action potential involved in regulation of contraction [GO:0098909]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cation channel activity [GO:2001257]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of membrane depolarization [GO:0003254]; regulation of membrane potential [GO:0042391]; regulation of SA node cell action potential [GO:0098907]; SA node cell action potential [GO:0086015]; sinoatrial node development [GO:0003163]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725] axon [GO:0030424]; dendrite [GO:0030425]; HCN channel complex [GO:0098855]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; intracellular cAMP-activated cation channel activity [GO:0005222]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated potassium channel activity involved in SA node cell action potential depolarization [GO:0086041]; voltage-gated sodium channel activity [GO:0005248] 0.95591 -1.5867 DKLPPSMR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.68591 0 0 0 0 0 0 0 0 Q9Y3Q7 ADA18_HUMAN "Disintegrin and metalloproteinase domain-containing protein 18 (ADAM 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III) (tMDC III)" ADAM18 TMDC3 UNQ858/PRO1867 Homo sapiens (Human) binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; male gonad development [GO:0008584]; proteolysis [GO:0006508]; spermatogenesis [GO:0007283] membrane [GO:0016020]; plasma membrane [GO:0005886] metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237] 0.88306 -0.26923 LACVQPHKNANK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.79672 0 0 0 0 0 0 0 0 0 0 0 Q9Y3Q8 T22D4_HUMAN TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) TSC22D4 THG1 THG1-PIT Homo sapiens (Human) glucose homeostasis [GO:0042593]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron cellular homeostasis [GO:0070050]; neuron projection extension [GO:1990138]; response to osmotic stress [GO:0006970] cytoplasm [GO:0005737]; dendrite [GO:0030425]; nucleus [GO:0005634]; synapse [GO:0045202] 0.88455 -0.3336 GASGGAGGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.55543 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y3R0 GRIP1_HUMAN Glutamate receptor-interacting protein 1 (GRIP-1) GRIP1 Homo sapiens (Human) "intracellular signal transduction [GO:0035556]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive regulation of neuron projection arborization [GO:0150012]" cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211] beta-catenin binding [GO:0008013]; nuclear glucocorticoid receptor binding [GO:0035259]; signaling receptor complex adaptor activity [GO:0030159] 0.83297 0.2014 EIMSPTPVELHK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2138 0 0 0 0 10.9763 0 0 0 0 0 Q9Y3R4 NEUR2_HUMAN Sialidase-2 (EC 3.2.1.18) (Cytosolic sialidase) (N-acetyl-alpha-neuraminidase 2) NEU2 Homo sapiens (Human) ganglioside catabolic process [GO:0006689]; glycoprotein catabolic process [GO:0006516]; glycosphingolipid metabolic process [GO:0006687]; oligosaccharide catabolic process [GO:0009313] catalytic complex [GO:1902494]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lysosome [GO:0005764]; membrane [GO:0016020] exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; exo-alpha-sialidase activity [GO:0004308] 0.45184 0.64206 ANVTRLCQVTSTDHGRTWSSPR 0 0 0 0 0 0 0 0 10.6829 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y3R5 DOP2_HUMAN Protein dopey-2 DOP1B C21orf5 DOPEY2 KIAA0933 Homo sapiens (Human) cognition [GO:0050890]; embryonic pattern specification [GO:0009880]; endoplasmic reticulum organization [GO:0007029]; Golgi to endosome transport [GO:0006895]; protein transport [GO:0015031] cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; trans-Golgi network [GO:0005802] 0.92388 -1.0162 NAILEELPRTVNTMALLWNVLR 0 0 0 0 0 0 9.30731 0 0 0 0 0 0 0 0 0 0 0 9.38269 0 0 0 0 0 0 0 0 Q9Y3S1 WNK2_HUMAN Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Antigen NY-CO-43) (Protein kinase lysine-deficient 2) (Protein kinase with no lysine 2) (Serologically defined colon cancer antigen 43) WNK2 KIAA1760 PRKWNK2 SDCCAG43 P/OKcl.13 Homo sapiens (Human) intracellular signal transduction [GO:0035556]; monoatomic ion homeostasis [GO:0050801]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468] cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.97021 -3.2958 AGVGMPR 0 0 12.9697 0 9.69406 0 0 0 8.07628 0 0 0 11.0385 9.65589 0 8.76722 0 0 0 9.29731 0 10.2365 8.54655 9.33749 0 0 10.5406 Q9Y3T9 NOC2L_HUMAN Nucleolar complex protein 2 homolog (Protein NOC2 homolog) (NOC2-like protein) (Novel INHAT repressor) NOC2L NIR Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to UV [GO:0034644]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of histone acetylation [GO:0035067]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ribosomal large subunit biogenesis [GO:0042273]; transcription initiation-coupled chromatin remodeling [GO:0045815] chromosome [GO:0005694]; cytosol [GO:0005829]; Noc1p-Noc2p complex [GO:0030690]; Noc2p-Noc3p complex [GO:0030691]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; DNA-binding transcription factor binding [GO:0140297]; histone binding [GO:0042393]; nucleosome binding [GO:0031491]; RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714] 0.90086 -0.69307 EEGTPLTLYYSHWRK 8.36072 0 0 0 0 0 0 0 0 0 0 8.66338 0 0 0 0 0 0 0 10.4195 0 0 0 0 0 0 0 Q9Y3U8 RL36_HUMAN Large ribosomal subunit protein eL36 (60S ribosomal protein L36) RPL36 Homo sapiens (Human) cytoplasmic translation [GO:0002181]; translation [GO:0006412] cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; membrane [GO:0016020]; nucleolus [GO:0005730]; polysomal ribosome [GO:0042788] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] 0.9172 -0.87409 EELSNVLAAMR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0419 0 0 9.34693 0 0 0 0 0 10.1224 0 Q9Y3X0 CCDC9_HUMAN Coiled-coil domain-containing protein 9 CCDC9 Homo sapiens (Human) exon-exon junction complex [GO:0035145] RNA binding [GO:0003723] 0.9675 -3.7966 AATLDLK 11.7112 0 10.2131 0 9.92291 0 0 0 0 11.5629 9.41318 12.2357 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y3Y2 CHTOP_HUMAN Chromatin target of PRMT1 protein (Friend of PRMT1 protein) (Small arginine- and glycine-rich protein) (SRAG) CHTOP C1orf77 FOP HT031 PP7704 Homo sapiens (Human) chromatin remodeling [GO:0006338]; in utero embryonic development [GO:0001701]; mRNA export from nucleus [GO:0006406]; positive regulation of ATP-dependent activity [GO:0032781]; positive regulation of helicase activity [GO:0051096] nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription export complex [GO:0000346] methyl-CpG binding [GO:0008327]; mRNA binding [GO:0003729]; RNA binding [GO:0003723] 0.91889 -0.88008 AVAPRMGLR 0 10.1856 0 9.09719 0 0 8.73505 0 0 0 0 0 0 0 0 0 0 0 0 9.24956 0 0 8.82107 0 0 0 0 Q9Y3Z3 SAMH1_HUMAN Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (dNTPase) (EC 3.1.5.-) (Dendritic cell-derived IFNG-induced protein) (DCIP) (Monocyte protein 5) (MOP-5) (SAM domain and HD domain-containing protein 1) (hSAMHD1) SAMHD1 MOP5 Homo sapiens (Human) dATP catabolic process [GO:0046061]; defense response to virus [GO:0051607]; deoxyribonucleotide catabolic process [GO:0009264]; dGTP catabolic process [GO:0006203]; DNA damage response [GO:0006974]; DNA strand resection involved in replication fork processing [GO:0110025]; double-strand break repair via homologous recombination [GO:0000724]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; protein homotetramerization [GO:0051289]; regulation of innate immune response [GO:0045088]; somatic hypermutation of immunoglobulin genes [GO:0016446] nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of double-strand break [GO:0035861]; tetraspanin-enriched microdomain [GO:0097197] deoxynucleoside triphosphate hydrolase activity [GO:0106375]; dGTP binding [GO:0032567]; dGTPase activity [GO:0008832]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; nucleic acid binding [GO:0003676]; RNA binding [GO:0003723]; RNA nuclease activity [GO:0004540]; single-stranded DNA binding [GO:0003697]; triphosphoric monoester hydrolase activity [GO:0016793]; zinc ion binding [GO:0008270] 0.72847 0.35044 DKEVGNLYDMFHTRNSLHR 0 0 0 8.6596 0 0 0 0 0 0 9.23848 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5006 0 0 Q9Y426 C2CD2_HUMAN C2 domain-containing protein 2 (Transmembrane protein 24-like) C2CD2 C21orf25 C21orf258 TMEM24L Homo sapiens (Human) cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634] 0.96355 -2.1177 DISVQAIACR 0 0 8.24436 0 0 0 8.95881 9.31619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y448 SKAP_HUMAN Small kinetochore-associated protein (SKAP) (Kinetochore-localized astrin-binding protein) (Kinastrin) (Kinetochore-localized astrin/SPAG5-binding protein) (TRAF4-associated factor 1) KNSTRN C15orf23 SKAP TRAF4AF1 HSD11 Homo sapiens (Human) cell division [GO:0051301]; cell migration [GO:0016477]; cellular response to epidermal growth factor stimulus [GO:0071364]; chromosome segregation [GO:0007059]; microtubule cytoskeleton organization [GO:0000226]; mitotic sister chromatid segregation [GO:0000070]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; spindle organization [GO:0007051] centriolar satellite [GO:0034451]; cytoplasm [GO:0005737]; kinetochore [GO:0000776]; microtubule organizing center [GO:0005815]; microtubule plus-end [GO:0035371]; mitotic spindle [GO:0072686]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; spindle pole [GO:0000922] microtubule plus-end binding [GO:0051010]; protein homodimerization activity [GO:0042803] 0.91394 -0.81834 LTETQGELKDLTQK 0 0 0 0 0 0 0 0 0 0 0 0 9.10127 0 0 0 0 0 0 0 0 0 0 0 0 0 11.9062 Q9Y450 HBS1L_HUMAN HBS1-like protein (EC 3.6.5.-) (ERFS) HBS1L HBS1 KIAA1038 Homo sapiens (Human) "nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; rescue of stalled ribosome [GO:0072344]; ribosome disassembly [GO:0032790]; signal transduction [GO:0007165]; translation [GO:0006412]" cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; Dom34-Hbs1 complex [GO:1990533]; extracellular exosome [GO:0070062]; membrane [GO:0016020] GTP binding [GO:0005525]; GTPase activity [GO:0003924]; molecular function activator activity [GO:0140677]; translation elongation factor activity [GO:0003746] 0.93346 -1.2833 INVGCIFCGPKVPIK 0 0 0 0 10.1342 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y458 TBX22_HUMAN T-box transcription factor TBX22 (T-box protein 22) TBX22 TBOX22 Homo sapiens (Human) cell fate specification [GO:0001708]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.93437 -1.2894 ETEFTTVTAYQNQQITK 0 0 0 0 0 0 0 0 0 0 0 10.3551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y462 ZN711_HUMAN Zinc finger protein 711 (Zinc finger protein 6) ZNF711 CMPX1 ZNF6 Homo sapiens (Human) positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]" 0.91832 -0.88548 CEHCPQAFGDER 0 9.84332 0 0 0 0 9.41321 0 9.33523 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y466 NR2E1_HUMAN Nuclear receptor subfamily 2 group E member 1 (Nuclear receptor TLX) (Protein tailless homolog) (Tll) (hTll) NR2E1 TLX Homo sapiens (Human) aggressive behavior [GO:0002118]; amygdala development [GO:0021764]; anatomical structure development [GO:0048856]; angiogenesis [GO:0001525]; anterior commissure morphogenesis [GO:0021960]; apoptotic process [GO:0006915]; astrocyte cell migration [GO:0043615]; astrocyte differentiation [GO:0048708]; behavioral fear response [GO:0001662]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; cerebral cortex neuron differentiation [GO:0021895]; dentate gyrus development [GO:0021542]; extracellular matrix organization [GO:0030198]; forebrain generation of neurons [GO:0021872]; layer formation in cerebral cortex [GO:0021819]; long-term synaptic potentiation [GO:0060291]; negative regulation of apoptotic process [GO:0043066]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of neural precursor cell proliferation [GO:2000178]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; neuroblast proliferation [GO:0007405]; olfactory bulb development [GO:0021772]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell cycle [GO:0045787]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of stem cell proliferation [GO:2000648]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of dendrite morphogenesis [GO:0048814]; regulation of timing of neuron differentiation [GO:0060164]; retina development in camera-type eye [GO:0060041]; social behavior [GO:0035176]; somatic stem cell population maintenance [GO:0035019]; visual perception [GO:0007601] chromatin [GO:0000785]; nucleoplasm [GO:0005654] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; histone deacetylase binding [GO:0042826]; nuclear receptor activity [GO:0004879]; nuclear steroid receptor activity [GO:0003707]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]; zinc ion binding [GO:0008270]" 0.96772 -3.7084 NRTYVCK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.71342 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y468 LMBL1_HUMAN Lethal(3)malignant brain tumor-like protein 1 (H-l(3)mbt) (H-l(3)mbt protein) (L(3)mbt-like) (L(3)mbt protein homolog) (L3MBTL1) L3MBTL1 KIAA0681 L3MBT L3MBTL Homo sapiens (Human) chromatin organization [GO:0006325]; hemopoiesis [GO:0030097]; heterochromatin formation [GO:0031507]; negative regulation of DNA-templated transcription [GO:0045892]; regulation of cell cycle [GO:0051726]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of mitotic nuclear division [GO:0007088] chromatin [GO:0000785]; chromatin lock complex [GO:0061793]; condensed chromosome [GO:0000793]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; histone binding [GO:0042393]; identical protein binding [GO:0042802]; methylated histone binding [GO:0035064]; nucleosome binding [GO:0031491]; SAM domain binding [GO:0032093]; zinc ion binding [GO:0008270] 0.35484 0.76089 YLEETGASAVPTWAFK 14.3807 14.5882 14.3215 11.6012 12.0399 11.971 13.948 13.9703 14.1229 14.0918 13.6384 13.8754 12.4599 12.6151 12.7111 13.0282 12.9048 12.8034 0 0 0 0 0 0 0 0 0 Q9Y473 ZN175_HUMAN Zinc finger protein 175 (Zinc finger protein OTK18) ZNF175 Homo sapiens (Human) defense response to virus [GO:0051607]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944] cytosol [GO:0005829]; nucleolus [GO:0005730] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]" 0.88421 -0.10852 KASFQKDMVGEFTR 0 0 0 0 0 0 10.6917 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y483 MTF2_HUMAN Metal-response element-binding transcription factor 2 (Metal regulatory transcription factor 2) (Metal-response element DNA-binding protein M96) (Polycomb-like protein 2) (hPCl2) MTF2 PCL2 Homo sapiens (Human) cellular response to leukemia inhibitory factor [GO:1990830]; chromatin organization [GO:0006325]; epigenetic regulation of gene expression [GO:0040029]; regulation of DNA-templated transcription [GO:0006355]; segment specification [GO:0007379]; stem cell differentiation [GO:0048863]; stem cell population maintenance [GO:0019827] cytoplasm [GO:0005737]; ESC/E(Z) complex [GO:0035098]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; methylated histone binding [GO:0035064]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; transcription corepressor binding [GO:0001222] 0.91377 -0.78498 NQKTPTSLTK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6204 0 0 0 0 0 0 0 0 0 0 Q9Y485 DMXL1_HUMAN DmX-like protein 1 (X-like 1 protein) DMXL1 XL1 Homo sapiens (Human) vacuolar acidification [GO:0007035] RAVE complex [GO:0043291] 0.9672 -2.8089 AVIWGLYR 0 0 10.887 0 0 10.7069 0 0 11.1318 0 0 0 10.5497 0 10.42 0 0 0 0 0 0 0 9.37221 0 0 10.1152 0 Q9Y490 TLN1_HUMAN Talin-1 TLN1 KIAA1027 TLN Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cell-cell junction assembly [GO:0007043]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; regulation of focal adhesion assembly [GO:0051893] adherens junction [GO:0005912]; cell surface [GO:0009986]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; ruffle membrane [GO:0032587] actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; integrin binding [GO:0005178]; LIM domain binding [GO:0030274]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166] 0.96757 -3.7129 AIADMLRACK 12.6987 0 0 0 9.52968 0 0 0 0 0 0 0 0 9.21298 8.22694 10.6137 0 0 0 0 0 0 9.45697 0 0 0 10.8872 Q9Y493 ZAN_HUMAN Zonadhesin ZAN Homo sapiens (Human) binding of sperm to zona pellucida [GO:0007339]; cell-cell adhesion [GO:0098609] extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] 0.92514 -0.95667 ECIYRTRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.53976 0 0 0 0 0 0 0 0 Q9Y496 KIF3A_HUMAN Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A) KIF3A KIF3 Homo sapiens (Human) anterograde axonal transport [GO:0008089]; centriole-centriole cohesion [GO:0010457]; cilium assembly [GO:0060271]; microtubule anchoring at centrosome [GO:0034454]; organelle organization [GO:0006996]; plus-end-directed vesicle transport along microtubule [GO:0072383]; protein localization to cell junction [GO:1902414]; protein transport [GO:0015031] axon cytoplasm [GO:1904115]; centriole [GO:0005814]; centrosome [GO:0005813]; ciliary tip [GO:0097542]; cilium [GO:0005929]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; kinesin complex [GO:0005871]; kinesin II complex [GO:0016939]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777]; plus-end-directed microtubule motor activity [GO:0008574]; protein phosphatase binding [GO:0019903]; small GTPase binding [GO:0031267]; spectrin binding [GO:0030507] 0.95341 -1.4951 EIEGLLENIRQLSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.82115 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y4A0 JERKL_HUMAN Jerky protein homolog-like (Human homolog of mouse jerky gene protein) (HHMJG) JRKL Homo sapiens (Human) central nervous system development [GO:0007417] nucleus [GO:0005634] DNA binding [GO:0003677] 0.95935 -1.7161 EINIRNER 0 0 0 0 0 0 0 0 0 0 0 0 0 9.92205 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y4A5 TRRAP_HUMAN Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog) TRRAP PAF400 Homo sapiens (Human) chromatin organization [GO:0006325]; DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H3 acetylation [GO:0043966]; histone H4 acetylation [GO:0043967]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of DNA repair [GO:0006282]; regulation of DNA-templated transcription [GO:0006355]; regulation of double-strand break repair [GO:2000779]; regulation of RNA splicing [GO:0043484]; regulation of transcription by RNA polymerase II [GO:0006357] Golgi apparatus [GO:0005794]; NuA4 histone acetyltransferase complex [GO:0035267]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; SAGA complex [GO:0000124]; Swr1 complex [GO:0000812]; transcription factor TFTC complex [GO:0033276] transcription coregulator activity [GO:0003712] 0.97014 -4.3138 AIETALDCLK 0 10.4085 0 0 0 0 0 0 0 0 8.81179 0 0 0 0 0 0 0 10.6976 0 0 0 9.08337 10.0041 9.96135 10.1652 0 Q9Y4A8 NF2L3_HUMAN "Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3)" NFE2L3 NRF3 Homo sapiens (Human) integrated stress response signaling [GO:0140467]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] chromatin [GO:0000785]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575] "DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.87817 -0.0045044 AGHLHPK 0 0 0 0 9.56674 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y4B4 ARIP4_HUMAN Helicase ARIP4 (EC 3.6.4.12) (Androgen receptor-interacting protein 4) (RAD54-like protein 2) RAD54L2 ARIP4 KIAA0809 Homo sapiens (Human) nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent chromatin remodeler activity [GO:0140658]; DNA binding [GO:0003677]; helicase activity [GO:0004386] 0.92021 -1.141 DLLTNYQTGVLENSPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0891 0 0 0 Q9Y4B5 MTCL1_HUMAN Microtubule cross-linking factor 1 (Coiled-coil domain-containing protein 165) (PAR-1-interacting protein) (SOGA family member 2) MTCL1 CCDC165 KIAA0802 SOGA2 Homo sapiens (Human) establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; microtubule bundle formation [GO:0001578]; positive regulation of protein targeting to membrane [GO:0090314]; regulation of autophagy [GO:0010506] apical plasma membrane [GO:0016324]; apicolateral plasma membrane [GO:0016327]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; extracellular space [GO:0005615]; lateral plasma membrane [GO:0016328]; microtubule bundle [GO:0097427]; midbody [GO:0030496]; spindle pole [GO:0000922] microtubule binding [GO:0008017]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723] 0.96951 -4.8915 AEMEDMRGQQER 0 0 0 11.7977 12.0631 0 0 0 0 13.3898 0 10.8203 0 0 0 0 10.5911 11.6288 0 0 0 9.49825 0 0 0 0 0 Q9Y4B6 DCAF1_HUMAN DDB1- and CUL4-associated factor 1 (HIV-1 Vpr-binding protein) (VprBP) (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) (Vpr-interacting protein) DCAF1 KIAA0800 RIP VPRBP Homo sapiens (Human) B cell differentiation [GO:0030183]; cell competition in a multicellular organism [GO:0035212]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphorylation [GO:0016310]; positive regulation of protein catabolic process [GO:0045732]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; V(D)J recombination [GO:0033151] Cul4-RING E3 ubiquitin ligase complex [GO:0080008]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; histone H2AT120 kinase activity [GO:1990244]; nuclear estrogen receptor binding [GO:0030331]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; ubiquitin ligase-substrate adaptor activity [GO:1990756] 0.9582 -1.6817 MSQLIEKETEEYRK 0 0 0 0 0 0 10.3295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4938 0 0 Q9Y4C0 NRX3A_HUMAN Neurexin-3 (Neurexin III-alpha) (Neurexin-3-alpha) NRXN3 C14orf60 KIAA0743 Homo sapiens (Human) adult behavior [GO:0030534]; axon guidance [GO:0007411]; learning [GO:0007612]; neuron cell-cell adhesion [GO:0007158]; social behavior [GO:0035176]; vocalization behavior [GO:0071625] cell projection [GO:0042995]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734] cell adhesion molecule binding [GO:0050839]; metal ion binding [GO:0046872]; neuroligin family protein binding [GO:0097109]; signaling receptor activity [GO:0038023] 0.96856 -7.8467 DSADTLRLELDGGR 0 0 0 0 10.4607 0 0 0 0 8.79614 0 0 9.45368 0 0 9.73201 0 10.0415 0 0 0 0 0 0 0 0 0 Q9Y4C1 KDM3A_HUMAN Lysine-specific demethylase 3A (EC 1.14.11.65) (JmjC domain-containing histone demethylation protein 2A) (Jumonji domain-containing protein 1A) ([histone H3]-dimethyl-L-lysine(9) demethylase 3A) KDM3A JHDM2A JMJD1 JMJD1A KIAA0742 TSGA Homo sapiens (Human) androgen receptor signaling pathway [GO:0030521]; cellular response to leukemia inhibitory factor [GO:1990830]; formaldehyde biosynthetic process [GO:0046293]; histone H3-K9 demethylation [GO:0033169]; hormone-mediated signaling pathway [GO:0009755]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of stem cell differentiation [GO:2000736]; regulation of stem cell population maintenance [GO:2000036]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatid nucleus elongation [GO:0007290] chromatin [GO:0000785]; cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; male germ cell nucleus [GO:0001673]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] chromatin DNA binding [GO:0031490]; histone H3K9 demethylase activity [GO:0032454]; histone H3K9me/H3K9me2 demethylase activity [GO:0140683]; iron ion binding [GO:0005506]; nuclear androgen receptor binding [GO:0050681]; transcription coregulator activity [GO:0003712] 0.96412 -2.4358 DAVAMLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0983 10.0541 0 10.787 8.58365 0 0 0 0 10.9319 0 Q9Y4C2 TCAF1_HUMAN TRPM8 channel-associated factor 1 (TRP channel-associated factor 1) TCAF1 FAM115A KIAA0738 Homo sapiens (Human) negative regulation of cell migration [GO:0030336]; positive regulation of anion channel activity [GO:1901529]; positive regulation of protein targeting to membrane [GO:0090314] plasma membrane [GO:0005886] transmembrane transporter binding [GO:0044325] 0.96382 -2.2162 GLWGPVHELGR 0 0 0 0 0 0 0 0 0 13.5751 0 0 0 0 0 0 0 0 0 0 0 0 10.2787 0 0 0 0 Q9Y4C4 MFHA1_HUMAN Malignant fibrous histiocytoma-amplified sequence 1 (Malignant fibrous histiocytoma-amplified sequence with leucine-rich tandem repeats 1) MFHAS1 MASL1 Homo sapiens (Human) erythrocyte differentiation [GO:0030218]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of inflammatory response [GO:0050728]; negative regulation of protein dephosphorylation [GO:0035308]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of JNK cascade [GO:0046330]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of toll-like receptor 2 signaling pathway [GO:0034137]; regulation of macrophage activation [GO:0043030]; regulation of toll-like receptor signaling pathway [GO:0034121] cytoplasm [GO:0005737] GTP binding [GO:0005525]; protein phosphatase 2A binding [GO:0051721]; ubiquitin protein ligase binding [GO:0031625] 0.87722 0.019813 AGMDSGNLKTAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.0021 12.099 0 0 0 0 0 0 0 12.1306 11.8623 0 Q9Y4C8 RBM19_HUMAN Probable RNA-binding protein 19 (RNA-binding motif protein 19) RBM19 KIAA0682 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; positive regulation of embryonic development [GO:0040019]" chromosome [GO:0005694]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] RNA binding [GO:0003723] 0.92189 -1.0864 EPTTCHTVK 0 0 10.6928 0 0 0 0 0 10.9259 13.127 8.71747 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y4D1 DAAM1_HUMAN Disheveled-associated activator of morphogenesis 1 DAAM1 KIAA0666 Homo sapiens (Human) "actin cytoskeleton organization [GO:0030036]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]" ciliary basal body [GO:0036064]; cytosol [GO:0005829]; membrane [GO:0016020]; motile cilium [GO:0031514]; plasma membrane [GO:0005886]; stress fiber [GO:0001725] actin binding [GO:0003779]; identical protein binding [GO:0042802]; small GTPase binding [GO:0031267] 0.54394 0.5775 AVETELEYQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.68909 0 9.98114 0 0 0 0 0 0 Q9Y4D2 DGLA_HUMAN Diacylglycerol lipase-alpha (DAGL-alpha) (DGL-alpha) (EC 3.1.1.116) (Neural stem cell-derived dendrite regulator) (Sn1-specific diacylglycerol lipase alpha) DAGLA C11orf11 KIAA0659 NSDDR Homo sapiens (Human) arachidonic acid metabolic process [GO:0019369]; diacylglycerol catabolic process [GO:0046340]; endocannabinoid signaling pathway [GO:0071926]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; neuroblast proliferation [GO:0007405]; neurotransmitter biosynthetic process [GO:0042136]; regulation of neuroinflammatory response [GO:0150077]; retrograde trans-synaptic signaling by endocannabinoid [GO:0098921] dendrite membrane [GO:0032590]; dendritic spine membrane [GO:0032591]; early endosome membrane [GO:0031901]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; varicosity [GO:0043196] acylglycerol lipase activity [GO:0047372]; lipoprotein lipase activity [GO:0004465]; metal ion binding [GO:0046872] 0.95428 -1.5347 AQFEPNLVPKPPR 0 0 0 0 0 0 0 0 0 9.63684 9.41555 0 0 0 8.87474 0 0 0 0 0 0 0 10.8623 0 0 9.64377 0 Q9Y4D7 PLXD1_HUMAN Plexin-D1 PLXND1 KIAA0620 Homo sapiens (Human) angiogenesis [GO:0001525]; aorta development [GO:0035904]; branching involved in blood vessel morphogenesis [GO:0001569]; cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; endothelial cell migration [GO:0043542]; kidney development [GO:0001822]; negative regulation of cell adhesion [GO:0007162]; negative regulation of neuron apoptotic process [GO:0043524]; outflow tract morphogenesis [GO:0003151]; positive regulation of axonogenesis [GO:0050772]; positive regulation of protein binding [GO:0032092]; regulation of angiogenesis [GO:0045765]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; synapse assembly [GO:0007416]; synaptic target recognition [GO:0008039] axon [GO:0030424]; cell body [GO:0044297]; glutamatergic synapse [GO:0098978]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; plasma membrane [GO:0005886]; semaphorin receptor complex [GO:0002116] protein domain specific binding [GO:0019904]; semaphorin receptor activity [GO:0017154] 0.96757 -2.8159 AMDTDTLTQVKEKILEAFCK 0 9.64544 0 0 0 0 0 0 0 0 9.29248 0 0 0 0 0 0 8.1103 0 0 0 10.269 0 0 0 10.3022 0 Q9Y4D8 HECD4_HUMAN Probable E3 ubiquitin-protein ligase HECTD4 (EC 2.3.2.26) (HECT domain-containing protein 4) (HECT-type E3 ubiquitin transferase HECTD4) HECTD4 C12orf51 KIAA0614 Homo sapiens (Human) glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein ubiquitination [GO:0016567] membrane [GO:0016020] ubiquitin-protein transferase activity [GO:0004842] 0.9693 -3.132 ASSSGKRQSSR 0 0 0 0 0 0 0 0 9.3168 0 0 0 9.71925 0 9.55434 0 0 0 0 0 0 0 10.0239 0 0 0 0 Q9Y4E5 ZN451_HUMAN E3 SUMO-protein ligase ZNF451 (EC 2.3.2.-) (Coactivator for steroid receptors) (E3 SUMO-protein transferase ZNF451) (Zinc finger protein 451) ZNF451 COASTER KIAA0576 KIAA1702 Homo sapiens (Human) negative regulation of transcription initiation by RNA polymerase II [GO:0060633]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; protein sumoylation [GO:0016925] nucleus [GO:0005634]; PML body [GO:0016605] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; SUMO ligase activity [GO:0061665]; transcription corepressor activity [GO:0003714]; transcription regulator inhibitor activity [GO:0140416]" 0.95489 -1.6196 GVENDLSYQNIEEEIVELPDLDYLR 0 0 0 0 0 0 0 0 10.9914 0 0 13.3147 9.88284 9.71105 0 0 0 0 0 0 0 10.1919 0 11.6348 0 0 0 Q9Y4E6 WDR7_HUMAN WD repeat-containing protein 7 (Rabconnectin-3 beta) (TGF-beta resistance-associated protein TRAG) WDR7 KIAA0541 TRAG Homo sapiens (Human) hematopoietic progenitor cell differentiation [GO:0002244] cytoplasm [GO:0005737] 0.88291 -0.08981 ISTSYEERR 0 10.6847 0 0 0 10.4764 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.1385 9.85123 Q9Y4E8 UBP15_HUMAN Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.4.19.12) (Deubiquitinating enzyme 15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Unph-2) (Unph4) USP15 KIAA0529 Homo sapiens (Human) BMP signaling pathway [GO:0030509]; monoubiquitinated protein deubiquitination [GO:0035520]; negative regulation of antifungal innate immune response [GO:1905035]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; positive regulation of RIG-I signaling pathway [GO:1900246]; protein deubiquitination [GO:0016579]; protein K27-linked deubiquitination [GO:1990167]; regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator [GO:1902238]; transcription elongation-coupled chromatin remodeling [GO:0140673]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] cysteine-type deubiquitinase activity [GO:0004843]; cysteine-type endopeptidase activity [GO:0004197]; deubiquitinase activity [GO:0101005]; enzyme activator activity [GO:0008047]; identical protein binding [GO:0042802]; K48-linked deubiquitinase activity [GO:1990380]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; ubiquitin modification-dependent histone binding [GO:0061649] 0.30647 0.80258 AEGGAADLDTQR 10.8041 0 0 0 0 0 10.7668 0 0 0 0 0 11.2842 9.99067 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y4F1 FARP1_HUMAN "FERM, ARHGEF and pleckstrin domain-containing protein 1 (Chondrocyte-derived ezrin-like protein) (FERM, RhoGEF and pleckstrin domain-containing protein 1) (Pleckstrin homology domain-containing family C member 2) (PH domain-containing family C member 2)" FARP1 CDEP PLEKHC2 Homo sapiens (Human) dendrite morphogenesis [GO:0048813]; postsynaptic actin cytoskeleton organization [GO:0098974]; regulation of presynapse assembly [GO:1905606]; retrograde trans-synaptic signaling by trans-synaptic protein complex [GO:0098942]; synapse assembly [GO:0007416] cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; extrinsic component of postsynaptic membrane [GO:0098890]; filopodium [GO:0030175]; glutamatergic synapse [GO:0098978] cytoskeletal protein binding [GO:0008092]; guanyl-nucleotide exchange factor activity [GO:0005085]; small GTPase binding [GO:0031267] 0.94045 -1.31 KHSKIHSIR 0 0 0 0 0 0 0 0 0 0 11.5767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y4F3 MARF1_HUMAN Meiosis regulator and mRNA stability factor 1 (Limkain-b1) (Meiosis arrest female protein 1) MARF1 KIAA0430 LKAP Homo sapiens (Human) double-strand break repair [GO:0006302]; female meiotic nuclear division [GO:0007143]; oogenesis [GO:0048477]; regulation of gene expression [GO:0010468] cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; peroxisome [GO:0005777] CCR4-NOT complex binding [GO:1905762]; mRNA base-pairing translational repressor activity [GO:1903231]; RNA nuclease activity [GO:0004540] 0.8349 0.1911 MENEDVFGNR 8.416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y4F4 TGRM1_HUMAN TOG array regulator of axonemal microtubules protein 1 (Crescerin-1) (Protein FAM179B) TOGARAM1 FAM179B KIAA0423 Homo sapiens (Human) axoneme assembly [GO:0035082]; cilium assembly [GO:0060271]; microtubule cytoskeleton organization [GO:0000226]; non-motile cilium assembly [GO:1905515]; positive regulation of microtubule polymerization [GO:0031116] axoneme [GO:0005930]; ciliary basal body [GO:0036064]; cilium [GO:0005929]; cytoplasmic microtubule [GO:0005881] microtubule binding [GO:0008017] 0.9165 -0.84623 AAVVCLSDLFTYLK 8.84618 8.90515 9.88484 13.4337 0 13.6784 9.76149 9.89881 0 9.79886 10.6851 9.31304 9.97885 10.1513 0 10.2235 0 0 0 9.19815 10.4852 0 10.6889 8.61357 0 0 0 Q9Y4F5 C170B_HUMAN Centrosomal protein of 170 kDa protein B (Centrosomal protein 170B) (Cep170B) CEP170B FAM68C KIAA0284 Homo sapiens (Human) cytoplasm [GO:0005737]; microtubule [GO:0005874] 0.96953 -3.0539 ELIFVGR 0 0 0 0 0 0 0 10.3641 0 0 0 0 0 0 0 0 0 0 0 0 11.1652 0 0 0 0 0 0 Q9Y4F9 RIPR2_HUMAN Rho family-interacting cell polarization regulator 2 RIPOR2 C6orf32 DIFF48 FAM65B KIAA0386 PL48 Homo sapiens (Human) cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cellular response to chemokine [GO:1990869]; chemotaxis [GO:0006935]; muscle organ development [GO:0007517]; negative regulation of cell adhesion [GO:0007162]; negative regulation of establishment of T cell polarity [GO:1903904]; negative regulation of protein localization to cell leading edge [GO:1905872]; negative regulation of Rho guanyl-nucleotide exchange factor activity [GO:2001107]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of T cell migration [GO:2000405]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of neutrophil extravasation [GO:2000391]; regulation of cell cycle [GO:0051726]; regulation of establishment of cell polarity [GO:2000114]; regulation of mitotic spindle assembly [GO:1901673]; sensory perception of sound [GO:0007605] apical plasma membrane [GO:0016324]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; filopodium [GO:0030175]; stereocilium [GO:0032420]; stereocilium membrane [GO:0060171] 14-3-3 protein binding [GO:0071889] 0.89021 -0.45858 ESLTEINR 10.1816 0 10.2207 0 0 0 0 0 0 10.775 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y4G2 PKHM1_HUMAN Pleckstrin homology domain-containing family M member 1 (PH domain-containing family M member 1) (162 kDa adapter protein) (AP162) PLEKHM1 KIAA0356 Homo sapiens (Human) autophagosome-lysosome fusion [GO:0061909]; late endosome to lysosome transport [GO:1902774]; lysosome localization [GO:0032418]; positive regulation of bone resorption [GO:0045780]; positive regulation of ruffle assembly [GO:1900029]; protein transport [GO:0015031] autolysosome [GO:0044754]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; nucleolus [GO:0005730] metal ion binding [GO:0046872] 0.9146 -0.80377 RGAMGIWK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.11964 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y4G6 TLN2_HUMAN Talin-2 TLN2 KIAA0320 Homo sapiens (Human) cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell junction assembly [GO:0007043] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; synapse [GO:0045202] actin binding [GO:0003779]; actin filament binding [GO:0051015]; integrin binding [GO:0005178]; structural constituent of cytoskeleton [GO:0005200]; structural molecule activity [GO:0005198] 0.96818 -9.2393 ADDDDVVVKTK 8.7788 0 0 0 0 0 0 0 9.61699 7.96711 0 0 0 8.34363 0 9.07173 9.43694 0 0 0 9.75661 10.2667 0 10.0616 10.6026 0 10.34 Q9Y4G8 RPGF2_HUMAN Rap guanine nucleotide exchange factor 2 (Cyclic nucleotide ras GEF) (CNrasGEF) (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF-1) (Ras/Rap1-associating GEF-1) RAPGEF2 KIAA0313 NRAPGEP PDZGEF1 Homo sapiens (Human) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; blood vessel development [GO:0001568]; brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to nerve growth factor stimulus [GO:1990090]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; forebrain neuron development [GO:0021884]; G protein-coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; microvillus assembly [GO:0030033]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of melanin biosynthetic process [GO:0048022]; nerve growth factor signaling pathway [GO:0038180]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; neuropeptide signaling pathway [GO:0007218]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron migration [GO:2001224]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of vasculogenesis [GO:2001214]; protein localization to plasma membrane [GO:0072659]; proteolysis [GO:0006508]; Rap protein signal transduction [GO:0032486]; Ras protein signal transduction [GO:0007265]; regulation of cell junction assembly [GO:1901888]; regulation of synaptic plasticity [GO:0048167]; small GTPase mediated signal transduction [GO:0007264]; ventricular system development [GO:0021591] apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle [GO:0030139]; late endosome [GO:0005770]; membrane [GO:0016020]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202] beta-1 adrenergic receptor binding [GO:0031697]; calcium ion binding [GO:0005509]; cAMP binding [GO:0030552]; diacylglycerol binding [GO:0019992]; GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; PDZ domain binding [GO:0030165]; phosphatidic acid binding [GO:0070300]; WW domain binding [GO:0050699] 0.89874 -0.61952 LFQDLQDLFDPSRNMAK 0 0 0 0 0 0 0 0 0 0 8.87086 0 0 0 0 0 0 0 0 0 0 0 9.64191 0 0 0 0 Q9Y4H2 IRS2_HUMAN Insulin receptor substrate 2 (IRS-2) IRS2 Homo sapiens (Human) brain development [GO:0007420]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; epithelial cell migration [GO:0010631]; glucose metabolic process [GO:0006006]; insulin receptor signaling pathway [GO:0008286]; lipid homeostasis [GO:0055088]; mammary gland development [GO:0030879]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of kinase activity [GO:0033673]; negative regulation of long-chain fatty acid import across plasma membrane [GO:0010748]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of glucose import [GO:0046326]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of type B pancreatic cell proliferation [GO:1904692]; regulation of lipid metabolic process [GO:0019216]; response to glucose [GO:0009749]; signal transduction [GO:0007165]; type B pancreatic cell proliferation [GO:0044342] cytosol [GO:0005829]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] 14-3-3 protein binding [GO:0071889]; insulin receptor binding [GO:0005158]; molecular function activator activity [GO:0140677]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068] 0.96923 -3.312 QRSPLSDYMNLDFSSPK 0 0 0 9.22364 0 0 0 0 0 9.716 13.533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y4I1 MYO5A_HUMAN "Unconventional myosin-Va (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myosin-12) (Myoxin)" MYO5A MYH12 Homo sapiens (Human) actin filament organization [GO:0007015]; actin filament-based movement [GO:0030048]; cellular response to insulin stimulus [GO:0032869]; melanosome transport [GO:0032402]; post-Golgi vesicle-mediated transport [GO:0006892]; protein localization to plasma membrane [GO:0072659]; protein transport [GO:0015031]; vesicle transport along actin filament [GO:0030050]; vesicle-mediated transport [GO:0016192] actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; filopodium tip [GO:0032433]; growth cone [GO:0030426]; insulin-responsive compartment [GO:0032593]; melanosome [GO:0042470]; membrane [GO:0016020]; myosin complex [GO:0016459]; neuron projection [GO:0043005]; ruffle [GO:0001726] actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; microfilament motor activity [GO:0000146]; RNA binding [GO:0003723]; small GTPase binding [GO:0031267] 0.97023 -4.3216 CIEEHADR 13.0126 12.0153 0 10.4577 10.7329 10.7766 12.2691 0 0 12.9855 0 0 11.3466 11.2289 11.5442 12.1675 0 10.1398 8.71809 0 11.5887 0 0 0 0 0 0 Q9Y4J8 DTNA_HUMAN Dystrobrevin alpha (DTN-A) (Alpha-dystrobrevin) (Dystrophin-related protein 3) DTNA DRP3 Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; neuromuscular synaptic transmission [GO:0007274]; signal transduction [GO:0007165]; striated muscle contraction [GO:0006941]; synaptic signaling [GO:0099536] cell junction [GO:0030054]; cytoplasm [GO:0005737]; intermediate filament cytoskeleton [GO:0045111]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202] zinc ion binding [GO:0008270] 0.95494 -1.6081 LAAESSSSQPPQQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.6783 0 0 0 0 0 0 10.3576 0 Q9Y4K1 CRBG1_HUMAN Beta/gamma crystallin domain-containing protein 1 (Absent in melanoma 1 protein) CRYBG1 AIM1 Homo sapiens (Human) carbohydrate binding [GO:0030246] 0.88415 -0.14324 DHKLLEKEDSEAADSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.53522 0 Q9Y4K3 TRAF6_HUMAN TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6) TRAF6 RNF85 Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; activation of protein kinase activity [GO:0032147]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antiviral innate immune response [GO:0140374]; bone resorption [GO:0045453]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cytosolic pattern recognition receptor signaling pathway [GO:0002753]; DNA damage response [GO:0006974]; Fc-epsilon receptor signaling pathway [GO:0038095]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; interleukin-17A-mediated signaling pathway [GO:0038173]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; NIK/NF-kappaB signaling [GO:0038061]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; response to interleukin-1 [GO:0070555]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; lipid droplet [GO:0005811]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; protein kinase B binding [GO:0043422]; protein serine/threonine kinase activator activity [GO:0043539]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; ubiquitin-ubiquitin ligase activity [GO:0034450]; zinc ion binding [GO:0008270] 0.96925 -3.987 EAVQTPCGHRFCK 13.2311 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y4K4 M4K5_HUMAN Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase homologous to SPS1/STE20) (KHS) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5) MAP4K5 Homo sapiens (Human) intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; MAP kinase kinase kinase kinase activity [GO:0008349]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.95442 -1.5057 IPDTKGCHK 0 0 11.0017 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y4L1 HYOU1_HUMAN Hypoxia up-regulated protein 1 (150 kDa oxygen-regulated protein) (ORP-150) (170 kDa glucose-regulated protein) (GRP-170) HYOU1 GRP170 ORP150 Homo sapiens (Human) "cellular response to hypoxia [GO:0071456]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903382]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; post-translational protein targeting to membrane, translocation [GO:0031204]; response to endoplasmic reticulum stress [GO:0034976]; response to ischemia [GO:0002931]" endocytic vesicle lumen [GO:0071682]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; membrane [GO:0016020]; smooth endoplasmic reticulum [GO:0005790] ATP binding [GO:0005524]; ATP-dependent protein folding chaperone [GO:0140662]; protein-folding chaperone binding [GO:0051087]; unfolded protein binding [GO:0051082] 0 42.13 DAVVYPILVEFTR 10.0723 10.0341 10.2754 0 0 0 0 0 0 0 8.86196 0 0 0 0 0 0 0 10.9521 9.96665 10.8992 9.97126 0 0 12.4486 11.567 11.3446 Q9Y4R7 TTLL3_HUMAN Tubulin monoglycylase TTLL3 (EC 6.3.2.-) (HOTTL) (Tubulin--tyrosine ligase-like protein 3) TTLL3 PRO0207 Homo sapiens (Human) axoneme assembly [GO:0035082]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; flagellated sperm motility [GO:0030317]; protein polyglycylation [GO:0018094] axoneme [GO:0005930]; cilium [GO:0005929]; cytosol [GO:0005829]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; sperm flagellum [GO:0036126] "ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein-glycine ligase activity [GO:0070735]; protein-glycine ligase activity, initiating [GO:0070736]" 0.92396 -1.026 ANSRPDCDKPR 0 10.8258 10.8913 0 0 0 0 0 10.977 9.57016 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y4R8 TELO2_HUMAN Telomere length regulation protein TEL2 homolog (Protein clk-2 homolog) (hCLK2) TELO2 KIAA0683 Homo sapiens (Human) positive regulation of DNA damage checkpoint [GO:2000003]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of TORC1 signaling [GO:1904263]; positive regulation of TORC2 signaling [GO:1904515]; protein stabilization [GO:0050821]; regulation of TOR signaling [GO:0032006]; telomere maintenance via telomerase [GO:0007004] "ASTRA complex [GO:0070209]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nuclear body [GO:0016604]; nuclear periphery [GO:0034399]; nucleus [GO:0005634]; TORC1 complex [GO:0031931]; TORC2 complex [GO:0031932]; TTT complex [GO:0110078]" Hsp90 protein binding [GO:0051879]; molecular adaptor activity [GO:0060090]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; telomeric DNA binding [GO:0042162] 0.83576 0.19411 DPDEDCR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.2951 0 0 0 0 0 0 0 0 0 0 Q9Y4W6 AFG32_HUMAN AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein) AFG3L2 Homo sapiens (Human) axonogenesis [GO:0007409]; calcium import into the mitochondrion [GO:0036444]; cristae formation [GO:0042407]; membrane protein proteolysis [GO:0033619]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial fusion [GO:0008053]; mitochondrial protein processing [GO:0034982]; muscle cell development [GO:0055001]; myelination [GO:0042552]; nerve development [GO:0021675]; neuromuscular junction development [GO:0007528]; protein autoprocessing [GO:0016540]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of multicellular organism growth [GO:0040014]; righting reflex [GO:0060013] m-AAA complex [GO:0005745]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; ATP-dependent peptidase activity [GO:0004176]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; unfolded protein binding [GO:0051082]; zinc ion binding [GO:0008270] 0.95946 -1.8621 ITTGAQDDLRK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4409 0 0 0 0 0 0 0 0 Q9Y4X5 ARI1_HUMAN E3 ubiquitin-protein ligase ARIH1 (EC 2.3.2.31) (H7-AP2) (HHARI) (Monocyte protein 6) (MOP-6) (Protein ariadne-1 homolog) (ARI-1) (UbcH7-binding protein) (UbcM4-interacting protein) (Ubiquitin-conjugating enzyme E2-binding protein 1) ARIH1 ARI MOP6 UBCH7BP HUSSY-27 Homo sapiens (Human) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] Cajal body [GO:0015030]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Lewy body [GO:0097413]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151] ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein transferase activity [GO:0019787]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270] 0.93866 -1.2949 LFAECHVINPSK 0 0 0 0 0 11.2088 0 0 0 0 0 0 0 10.5104 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y4Z0 LSM4_HUMAN U6 snRNA-associated Sm-like protein LSm4 (Glycine-rich protein) (GRP) LSM4 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process [GO:0000956]; P-body assembly [GO:0033962]; RNA splicing [GO:0008380]; spliceosomal snRNP assembly [GO:0000387]" cytosol [GO:0005829]; Lsm2-8 complex [GO:0120115]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; protein-containing complex [GO:0032991]; spliceosomal tri-snRNP complex [GO:0097526]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U6 snRNP [GO:0005688] PH domain binding [GO:0042731]; RNA binding [GO:0003723]; U6 snRNA binding [GO:0017070] 0.96916 -6.5482 GGLQQQK 0 9.84262 0 0 0 0 0 0 0 0 0 0 9.90573 0 0 0 0 0 0 9.13235 0 9.86423 9.15831 0 0 0 0 Q9Y512 SAM50_HUMAN Sorting and assembly machinery component 50 homolog (Transformation-related gene 3 protein) (TRG-3) SAMM50 SAM50 CGI-51 TRG3 Homo sapiens (Human) cristae formation [GO:0042407]; inner mitochondrial membrane organization [GO:0007007]; mitochondrial respiratory chain complex assembly [GO:0033108]; protein insertion into mitochondrial outer membrane [GO:0045040] extracellular exosome [GO:0070062]; membrane [GO:0016020]; MIB complex [GO:0140275]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; SAM complex [GO:0001401] 0.80201 0.23982 VTGQFPWSSLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2785 0 Q9Y520 PRC2C_HUMAN Protein PRRC2C (BAT2 domain-containing protein 1) (HBV X-transactivated gene 2 protein) (HBV XAg-transactivated protein 2) (HLA-B-associated transcript 2-like 2) (Proline-rich and coiled-coil-containing protein 2C) PRRC2C BAT2D1 BAT2L2 KIAA1096 XTP2 Homo sapiens (Human) hematopoietic progenitor cell differentiation [GO:0002244]; stress granule assembly [GO:0034063] cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; membrane [GO:0016020] RNA binding [GO:0003723] 0.96767 -2.7947 AEVLQSTQR 8.93342 0 0 0 0 0 10.5135 0 0 10.5628 9.40661 0 0 0 0 0 0 0 0 0 9.31102 10.5587 10.5379 9.86963 0 0 0 Q9Y530 OARD1_HUMAN ADP-ribose glycohydrolase OARD1 (O-acetyl-ADP-ribose deacetylase 1) (EC 3.5.1.-) (Terminal ADP-ribose protein glycohydrolase 1) ([Protein ADP-ribosylglutamate] hydrolase OARD1) (EC 3.2.2.-) OARD1 C6orf130 TARG1 Homo sapiens (Human) DNA damage response [GO:0006974]; peptidyl-glutamate ADP-deribosylation [GO:0140291]; protein de-ADP-ribosylation [GO:0051725]; purine nucleoside metabolic process [GO:0042278] nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; site of DNA damage [GO:0090734] ADP-ribosylglutamate hydrolase activity [GO:0140293]; O-acetyl-ADP-ribose deacetylase activity [GO:0061463]; purine nucleoside binding [GO:0001883] 0.95401 -1.5012 SLEAMKSHCLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.24401 0 0 0 Q9Y536 PAL4A_HUMAN Peptidyl-prolyl cis-trans isomerase A-like 4A (PPIase A-like 4A) (EC 5.2.1.8) (Chromosome one-amplified sequence 2) (COAS-2) (Cyclophilin homolog overexpressed in liver cancer) PPIAL4A COAS2 PPIAL4B Homo sapiens (Human) protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413] cytoplasm [GO:0005737]; extracellular exosome [GO:0070062] cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755] 0.92063 -1.1418 HNGTGDK 0 0 0 0 0 0 0 0 0 0 9.71168 0 0 0 0 0 0 0 0 0 9.18329 0 0 0 0 0 0 Q9Y543 HES2_HUMAN Transcription factor HES-2 (Class B basic helix-loop-helix protein 40) (bHLHb40) (Hairy and enhancer of split 2) HES2 BHLHB40 Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; regulation of neurogenesis [GO:0050767]; regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; protein dimerization activity [GO:0046983]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.93992 -1.3015 LEKADVLEMTVR 0 0 0 0 0 0 0 0 0 10.8799 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y546 LRC42_HUMAN Leucine-rich repeat-containing protein 42 LRRC42 Homo sapiens (Human) 0.96815 -2.7818 LFSAAEARQK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1124 0 0 0 Q9Y547 IFT25_HUMAN Intraflagellar transport protein 25 homolog (Heat shock protein beta-11) (Hspb11) (Placental protein 25) (PP25) IFT25 C1orf41 HSPB11 HSPC034 Homo sapiens (Human) cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; heart development [GO:0007507]; intraciliary anterograde transport [GO:0035720]; kidney development [GO:0001822]; left/right axis specification [GO:0070986]; lung development [GO:0030324]; protein transport [GO:0015031]; skeletal system development [GO:0001501]; smoothened signaling pathway [GO:0007224]; spermatogenesis [GO:0007283] centrosome [GO:0005813]; ciliary tip [GO:0097542]; cilium [GO:0005929]; intraciliary transport particle B [GO:0030992] metal ion binding [GO:0046872] 0.92437 -0.95235 IEKSTSKEPVDFEQWIEK 10.8348 10.6668 0 0 0 0 0 0 10.9582 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y561 LRP12_HUMAN Low-density lipoprotein receptor-related protein 12 (LDLR-related protein 12) (LRP-12) (Suppressor of tumorigenicity 7 protein) LRP12 ST7 Homo sapiens (Human) endocytosis [GO:0006897]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; regulation of growth [GO:0040008]; signal transduction [GO:0007165] clathrin-coated pit [GO:0005905]; membrane [GO:0016020]; plasma membrane [GO:0005886] low-density lipoprotein particle receptor activity [GO:0005041] 0.88575 -0.29475 NGVCYPRSDR 0 0 0 0 0 0 10.1396 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y566 SHAN1_HUMAN SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP) SHANK1 Homo sapiens (Human) adult behavior [GO:0030534]; associative learning [GO:0008306]; dendritic spine morphogenesis [GO:0060997]; determination of affect [GO:0050894]; habituation [GO:0046959]; long-term memory [GO:0007616]; negative regulation of actin filament bundle assembly [GO:0032232]; neuromuscular process controlling balance [GO:0050885]; olfactory behavior [GO:0042048]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of excitatory postsynaptic potential [GO:2000463]; protein localization to synapse [GO:0035418]; protein-containing complex assembly [GO:0065003]; regulation of AMPA receptor activity [GO:2000311]; righting reflex [GO:0060013]; social behavior [GO:0035176]; synapse maturation [GO:0060074]; vocalization behavior [GO:0071625] cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; Schaffer collateral - CA1 synapse [GO:0098685] ankyrin repeat binding [GO:0071532]; identical protein binding [GO:0042802]; ionotropic glutamate receptor binding [GO:0035255]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; SH3 domain binding [GO:0017124]; somatostatin receptor binding [GO:0031877]; structural constituent of postsynaptic density [GO:0098919]; synaptic receptor adaptor activity [GO:0030160] 0.96418 -2.2757 TVYQMALNK 10.2745 0 0 0 0 0 0 0 0 0 0 0 0 0 9.64203 0 0 0 0 0 0 0 0 0 0 0 8.8029 Q9Y572 RIPK3_HUMAN Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) RIPK3 RIP3 Homo sapiens (Human) "activation of protein kinase activity [GO:0032147]; amyloid fibril formation [GO:1990000]; apoptotic signaling pathway [GO:0097190]; cellular response to hydrogen peroxide [GO:0070301]; defense response to virus [GO:0051607]; execution phase of necroptosis [GO:0097528]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; lymph node development [GO:0048535]; necroptotic process [GO:0070266]; necroptotic signaling pathway [GO:0097527]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of ligase activity [GO:0051351]; positive regulation of necroptotic process [GO:0060545]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of phosphatase activity [GO:0010922]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; programmed necrotic cell death [GO:0097300]; protein autophosphorylation [GO:0046777]; protein modification process [GO:0036211]; reactive oxygen species metabolic process [GO:0072593]; regulation of activated T cell proliferation [GO:0046006]; regulation of activation-induced cell death of T cells [GO:0070235]; regulation of adaptive immune response [GO:0002819]; regulation of apoptotic process [GO:0042981]; regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000452]; regulation of T cell mediated cytotoxicity [GO:0001914]; regulation of type II interferon production [GO:0032649]; signal transduction [GO:0007165]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] ATP binding [GO:0005524]; identical protein binding [GO:0042802]; NF-kappaB-inducing kinase activity [GO:0004704]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein-containing complex binding [GO:0044877]; transcription coactivator activity [GO:0003713] 0.96198 -2.5546 ELMQLCWSSEPK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2232 0 0 0 11.1033 0 0 0 0 Q9Y574 ASB4_HUMAN Ankyrin repeat and SOCS box protein 4 (ASB-4) ASB4 Homo sapiens (Human) intracellular signal transduction [GO:0035556]; positive regulation of vasculogenesis [GO:2001214]; protein autoubiquitination [GO:0051865] Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829] ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842] 0.95496 -1.5765 AIPDDDLEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.104 0 Q9Y575 ASB3_HUMAN Ankyrin repeat and SOCS box protein 3 (ASB-3) ASB3 Homo sapiens (Human) intracellular signal transduction [GO:0035556]; protein localization to T-tubule [GO:0036371]; protein ubiquitination [GO:0016567]; regulation of cardiac muscle contraction [GO:0055117] cytosol [GO:0005829]; T-tubule [GO:0030315] 0.95891 -1.7161 YEKFSIFR 0 0 0 0 0 0 8.44927 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y576 ASB1_HUMAN Ankyrin repeat and SOCS box protein 1 (ASB-1) ASB1 KIAA1146 Homo sapiens (Human) intracellular signal transduction [GO:0035556]; male genitalia development [GO:0030539]; negative regulation of cytokine production [GO:0001818]; protein ubiquitination [GO:0016567] cytosol [GO:0005829]; ubiquitin ligase complex [GO:0000151] 0.42065 0.67233 SLLQEESYR 0 0 0 0 0 0 0 0 0 0 0 0 0 9.37036 0 0 0 0 10.4613 0 0 0 0 9.34851 0 0 0 Q9Y584 TIM22_HUMAN Mitochondrial import inner membrane translocase subunit Tim22 (Testis-expressed protein 4) TIMM22 TEX4 TIM22 Homo sapiens (Human) protein insertion into mitochondrial inner membrane [GO:0045039] mitochondrial inner membrane [GO:0005743]; TIM22 mitochondrial import inner membrane insertion complex [GO:0042721] mitochondrion targeting sequence binding [GO:0030943]; protein transmembrane transporter activity [GO:0008320]; protein transporter activity [GO:0140318] 0.91363 -0.78502 GMSYAKNFAIVGAMFSCTECLIESYR 9.99704 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y586 MB212_HUMAN Protein mab-21-like 2 MAB21L2 Homo sapiens (Human) camera-type eye development [GO:0043010]; cell population proliferation [GO:0008283]; embryonic body morphogenesis [GO:0010172]; eye development [GO:0001654]; nervous system development [GO:0007399]; positive regulation of cell population proliferation [GO:0008284] cytoplasm [GO:0005737]; nucleus [GO:0005634] 0.95431 -1.5055 YYTERCQAR 0 0 0 0 0 0 0 0 0 9.47084 0 9.00585 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y592 CEP83_HUMAN Centrosomal protein of 83 kDa (Cep83) (Coiled-coil domain-containing protein 41) (Renal carcinoma antigen NY-REN-58) CEP83 CCDC41 Homo sapiens (Human) cilium assembly [GO:0060271]; establishment of centrosome localization [GO:0051660]; protein localization to centrosome [GO:0071539]; vesicle docking [GO:0048278] centriole [GO:0005814]; centrosome [GO:0005813]; ciliary transition fiber [GO:0097539]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794] identical protein binding [GO:0042802] 0.8837 -0.10951 LEELETTQRKQLEELGSSGE 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.01106 0 0 0 8.45504 0 0 10.5379 0 0 0 0 Q9Y5A7 NUB1_HUMAN NEDD8 ultimate buster 1 (Negative regulator of ubiquitin-like proteins 1) (Renal carcinoma antigen NY-REN-18) NUB1 NYREN18 Homo sapiens (Human) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein ubiquitination [GO:0016567]; regulation of ubiquitin-dependent protein catabolic process [GO:2000058]; response to tumor necrosis factor [GO:0034612]; response to type II interferon [GO:0034341]; ubiquitin-dependent protein catabolic process [GO:0006511] cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] 0.8848 -0.21399 ALMLAMGYHEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.86071 0 0 0 0 0 0 0 0 0 Q9Y5A9 YTHD2_HUMAN YTH domain-containing family protein 2 (DF2) (CLL-associated antigen KW-14) (High-glucose-regulated protein 8) (Renal carcinoma antigen NY-REN-2) YTHDF2 HGRG8 Homo sapiens (Human) cell cycle [GO:0007049]; embryonic morphogenesis [GO:0048598]; endothelial to hematopoietic transition [GO:0098508]; gamete generation [GO:0007276]; hematopoietic stem cell proliferation [GO:0071425]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; oocyte maturation [GO:0001556]; organelle assembly [GO:0070925]; positive regulation of cap-independent translational initiation [GO:1903679]; regulation of cell adhesion [GO:0030155]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of meiotic cell cycle process involved in oocyte maturation [GO:1903538]; regulation of mRNA stability [GO:0043488]; regulation of neurogenesis [GO:0050767]; regulation of rRNA processing [GO:2000232]; spermatogonial cell division [GO:0007284]; stress granule assembly [GO:0034063] centriolar satellite [GO:0034451]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleus [GO:0005634]; P-body [GO:0000932] C5-methylcytidine-containing RNA binding [GO:0062153]; mRNA binding [GO:0003729]; N6-methyladenosine-containing RNA binding [GO:1990247]; RNA binding [GO:0003723] 0.59496 0.44707 HTTSIFDDFSHYEK 10.1262 0 0 0 0 0 0 0 0 11.6236 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y5B0 CTDP1_HUMAN RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase) CTDP1 FCP1 Homo sapiens (Human) cell division [GO:0051301]; exit from mitosis [GO:0010458]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; positive regulation by host of viral transcription [GO:0043923]; protein dephosphorylation [GO:0006470]; transcription elongation by RNA polymerase II [GO:0006368] centrosome [GO:0005813]; cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle [GO:0005819]; spindle midzone [GO:0051233]; spindle pole [GO:0000922] myosin phosphatase activity [GO:0017018]; phosphoprotein phosphatase activity [GO:0004721]; RNA polymerase II CTD heptapeptide repeat phosphatase activity [GO:0008420]; Tat protein binding [GO:0030957]; TFIIF-class transcription factor complex binding [GO:0001096] 0.89855 -0.65358 ERTLGAPASSER 0 0 0 0 0 0 0 0 0 0 0 0 8.23826 0 0 0 0 0 0 8.9271 0 0 0 0 0 0 0 Q9Y5B6 PAXB1_HUMAN PAX3- and PAX7-binding protein 1 (GC-rich sequence DNA-binding factor 1) PAXBP1 C21orf66 GCFC GCFC1 Homo sapiens (Human) "mRNA splicing, via spliceosome [GO:0000398]; muscle organ development [GO:0007517]; positive regulation of myoblast proliferation [GO:2000288]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of skeletal muscle satellite cell proliferation [GO:0014842]; transcription by RNA polymerase II [GO:0006366]" cytosol [GO:0005829]; nucleus [GO:0005634] DNA binding [GO:0003677]; histone methyltransferase binding [GO:1990226] 0.96778 -2.7454 LEGSSGGIGER 0 10.1678 9.86188 0 0 0 0 0 0 11.5928 10.2883 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y5B9 SP16H_HUMAN FACT complex subunit SPT16 (Chromatin-specific transcription elongation factor 140 kDa subunit) (FACT 140 kDa subunit) (FACTp140) (Facilitates chromatin transcription complex subunit SPT16) (hSPT16) SUPT16H FACT140 FACTP140 Homo sapiens (Human) "DNA repair [GO:0006281]; DNA replication [GO:0006260]; nucleosome assembly [GO:0006334]; nucleosome disassembly [GO:0006337]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; transcription by RNA polymerase II [GO:0006366]; transcription elongation by RNA polymerase II [GO:0006368]" FACT complex [GO:0035101]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] nucleosome binding [GO:0031491]; RNA binding [GO:0003723] 0.96941 -3.5851 EPHIREMK 0 0 10.0884 0 0 0 0 0 0 10.1477 8.11416 0 0 0 0 0 0 0 0 0 0 0 0 9.91228 0 0 0 Q9Y5E1 PCDB9_HUMAN Protocadherin beta-9 (PCDH-beta-9) (Protocadherin-3H) PCDHB9 PCDH3H Homo sapiens (Human) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; synapse assembly [GO:0007416] membrane [GO:0016020]; plasma membrane [GO:0005886]; synapse [GO:0045202] calcium ion binding [GO:0005509] 0.74573 0.31867 DNGEPPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.40244 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y5E5 PCDB4_HUMAN Protocadherin beta-4 (PCDH-beta-4) PCDHB4 Homo sapiens (Human) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399]; synapse assembly [GO:0007416] membrane [GO:0016020]; plasma membrane [GO:0005886]; synapse [GO:0045202] calcium ion binding [GO:0005509] 0.73105 0.33704 DNGEPPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5835 0 0 Q9Y5E6 PCDB3_HUMAN Protocadherin beta-3 (PCDH-beta-3) PCDHB3 Homo sapiens (Human) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399]; synapse assembly [GO:0007416] membrane [GO:0016020]; plasma membrane [GO:0005886]; synapse [GO:0045202] calcium ion binding [GO:0005509] 0.89765 -0.55181 DNGEPPR 0 0 0 0 0 0 0 0 0 0 10.1135 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y5F1 PCDBC_HUMAN Protocadherin beta-12 (PCDH-beta-12) PCDHB12 Homo sapiens (Human) cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399] plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.87308 0.035211 DNGEPPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0222 0 0 0 0 0 0 0 Q9Y5F2 PCDBB_HUMAN Protocadherin beta-11 (PCDH-beta-11) PCDHB11 Homo sapiens (Human) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399]; synapse assembly [GO:0007416] membrane [GO:0016020]; plasma membrane [GO:0005886]; synapse [GO:0045202] calcium ion binding [GO:0005509] 0.95522 -1.5801 DNGEPPR 0 0 0 0 0 0 0 0 0 0 0 8.92419 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y5F3 PCDB1_HUMAN Protocadherin beta-1 (PCDH-beta-1) PCDHB1 Homo sapiens (Human) cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399] plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.87232 0.031382 IPESTPLGSR 0 0 0 0 0 0 0 0 0 0 10.301 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y5F9 PCDGI_HUMAN Protocadherin gamma-B6 (PCDH-gamma-B6) PCDHGB6 Homo sapiens (Human) cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399] plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.96814 -3.628 APAGGNGNK 0 0 0 0 0 0 9.65001 0 0 0 0 8.25016 0 0 0 0 0 0 0 0 10.936 0 0 0 0 0 0 Q9Y5G0 PCDGH_HUMAN Protocadherin gamma-B5 (PCDH-gamma-B5) PCDHGB5 Homo sapiens (Human) cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399] extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.88874 -0.42508 APAGGNGNK 0 0 0 0 0 9.56742 0 9.27268 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y5G1 PCDGF_HUMAN Protocadherin gamma-B3 (PCDH-gamma-B3) PCDHGB3 Homo sapiens (Human) cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399] plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.69851 0.3738 APAGGNGNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0448 0 0 0 0 0 0 0 0 0 0 0 Q9Y5G3 PCDGD_HUMAN Protocadherin gamma-B1 (PCDH-gamma-B1) PCDHGB1 Homo sapiens (Human) cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399] growth cone [GO:0030426]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.93019 -1.2471 APAGGNGNK 9.36091 9.22533 0 0 0 0 0 0 0 10.3201 9.88786 9.9629 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y5G4 PCDG9_HUMAN Protocadherin gamma-A9 (PCDH-gamma-A9) PCDHGA9 Homo sapiens (Human) cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399] plasma membrane [GO:0005886] calcium ion binding [GO:0005509]; RNA binding [GO:0003723] 0.97011 -3.2802 APAGGNGNK 0 0 0 10.0932 9.67165 0 0 0 0 0 0 0 0 8.78663 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y5G5 PCDG8_HUMAN Protocadherin gamma-A8 (PCDH-gamma-A8) PCDHGA8 KIAA0327 Homo sapiens (Human) cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399] plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.96771 -2.956 APAGGNGNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.6079 10.0086 0 Q9Y5G6 PCDG7_HUMAN Protocadherin gamma-A7 (PCDH-gamma-A7) PCDHGA7 Homo sapiens (Human) cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399] plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.9672 -2.8081 APAGGNGNK 0 0 0 0 0 0 0 0 0 0 13.0187 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3676 Q9Y5G7 PCDG6_HUMAN Protocadherin gamma-A6 (PCDH-gamma-A6) PCDHGA6 Homo sapiens (Human) cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399] plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.70131 0.37157 APAGGNGNK 0 0 0 0 0 0 0 0 10.9876 0 0 0 0 0 0 0 0 0 0 0 10.0077 9.38252 0 0 0 0 0 Q9Y5H0 PCDG3_HUMAN Protocadherin gamma-A3 (PCDH-gamma-A3) PCDHGA3 Homo sapiens (Human) cell adhesion [GO:0007155]; endosome to lysosome transport [GO:0008333]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lipid tube assembly involved in organelle fusion [GO:0060989]; nervous system development [GO:0007399] plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.92792 -1.2243 APAGGNGNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3882 0 0 0 0 0 0 12.2937 0 Q9Y5H2 PCDGB_HUMAN Protocadherin gamma-A11 (PCDH-gamma-A11) PCDHGA11 Homo sapiens (Human) cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399] plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.95951 -1.7899 APAGGNGNK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3179 Q9Y5H3 PCDGA_HUMAN Protocadherin gamma-A10 (PCDH-gamma-A10) PCDHGA10 Homo sapiens (Human) cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399] plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.87155 0.029505 APAGGNGNK 0 0 0 0 0 0 9.76638 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y5H6 PCDA8_HUMAN Protocadherin alpha-8 (PCDH-alpha-8) PCDHA8 Homo sapiens (Human) cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399] plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.89561 -0.52041 LFVSESRMPDSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1473 0 0 0 0 0 0 0 0 0 0 Q9Y5H8 PCDA3_HUMAN Protocadherin alpha-3 (PCDH-alpha-3) PCDHA3 Homo sapiens (Human) cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399] plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.94324 -1.338 ALDEVDAPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.50291 0 0 0 0 0 0 0 0 0 Q9Y5I0 PCDAD_HUMAN Protocadherin alpha-13 (PCDH-alpha-13) PCDHA13 CNRS5 Homo sapiens (Human) cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399] plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.8738 0.023445 MLSSWQGGPRPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.70753 0 Q9Y5I2 PCDAA_HUMAN Protocadherin alpha-10 (PCDH-alpha-10) PCDHA10 CNRS8 Homo sapiens (Human) cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399] extracellular region [GO:0005576]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.88116 -0.30758 ALDETDSPRQR 0 0 0 0 0 0 0 0 0 0 0 9.27608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y5I3 PCDA1_HUMAN Protocadherin alpha-1 (PCDH-alpha-1) PCDHA1 Homo sapiens (Human) cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399] endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; plasma membrane [GO:0005886] calcium ion binding [GO:0005509] 0.8805 0.0060039 DLLEVNLQNGILFVNSR 0 0 0 0 0 0 0 0 0 0 0 0 8.8662 0 12.0484 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y5I7 CLD16_HUMAN Claudin-16 (Paracellin-1) (PCLN-1) CLDN16 PCLN1 Homo sapiens (Human) bicellular tight junction assembly [GO:0070830]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; intercellular transport [GO:0010496]; intracellular monoatomic cation homeostasis [GO:0030003]; metal ion transport [GO:0030001] bicellular tight junction [GO:0005923]; plasma membrane [GO:0005886] identical protein binding [GO:0042802]; magnesium ion transmembrane transporter activity [GO:0015095]; structural molecule activity [GO:0005198] 0.91624 -0.76987 AYSAAGVSMAKSYSAPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.909 0 0 0 0 0 0 0 0 0 0 0 Q9Y5J1 UTP18_HUMAN U3 small nucleolar RNA-associated protein 18 homolog (WD repeat-containing protein 50) UTP18 WDR50 CDABP0061 CGI-48 Homo sapiens (Human) ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364] nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Pwp2p-containing subcomplex of 90S preribosome [GO:0034388]; small-subunit processome [GO:0032040] RNA binding [GO:0003723] 0.91796 -0.86792 LEEDKPAVER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.79276 0 0 0 0 0 Q9Y5K2 KLK4_HUMAN Kallikrein-4 (EC 3.4.21.-) (Enamel matrix serine proteinase 1) (Kallikrein-like protein 1) (KLK-L1) (Prostase) (Serine protease 17) KLK4 EMSP1 PRSS17 PSTS Homo sapiens (Human) amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508] extracellular region [GO:0005576] metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236] 0.88376 -0.28083 FTEWIEKTVQAS 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.92787 Q9Y5K6 CD2AP_HUMAN CD2-associated protein (Adapter protein CMS) (Cas ligand with multiple SH3 domains) CD2AP Homo sapiens (Human) "actin filament organization [GO:0007015]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; negative regulation of small GTPase mediated signal transduction [GO:0051058]; negative regulation of transforming growth factor beta1 production [GO:0032911]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein secretion [GO:0050714]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein-containing complex assembly [GO:0065003]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of receptor-mediated endocytosis [GO:0048259]; signal transduction [GO:0007165]; substrate-dependent cell migration, cell extension [GO:0006930]; synapse organization [GO:0050808]; transforming growth factor beta1 production [GO:0032905]; vesicle organization [GO:0016050]" actin cytoskeleton [GO:0015629]; axon [GO:0030424]; cell leading edge [GO:0031252]; cell-cell junction [GO:0005911]; centriolar satellite [GO:0034451]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; filamentous actin [GO:0031941]; neuromuscular junction [GO:0031594]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; vesicle [GO:0031982] beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; SH3 domain binding [GO:0017124]; structural constituent of cytoskeleton [GO:0005200]; vascular endothelial growth factor receptor binding [GO:0005172] 0.95274 -1.4649 ANTTAFLTPLEIKAK 0 0 9.1219 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y5M8 SRPRB_HUMAN Signal recognition particle receptor subunit beta (SR-beta) (Protein APMCF1) SRPRB PSEC0230 Homo sapiens (Human) "protein targeting to ER [GO:0045047]; SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition [GO:0006617]" cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; signal recognition particle receptor complex [GO:0005785] GTP binding [GO:0005525] 0.84886 0.15466 VADGGGAGGTFQPYLDTLR 0 0 0 0 0 0 0 0 9.79635 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9023 Q9Y5P0 O51B4_HUMAN Olfactory receptor 51B4 (Odorant receptor HOR5'beta1) OR51B4 Homo sapiens (Human) sensory perception of smell [GO:0007608] membrane [GO:0016020]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.43007 0.65769 LFSGQSR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.3079 0 0 8.45972 0 0 0 0 0 0 Q9Y5P1 O51B2_HUMAN Olfactory receptor 51B2 (Odorant receptor HOR5'beta3) (Olfactory receptor 51B1) OR51B2 OR51B1P Homo sapiens (Human) plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; olfactory receptor activity [GO:0004984] 0.91627 -0.8093 LFSFSYCKSHVITR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.56624 0 0 0 0 0 0 Q9Y5P2 CSAG2_HUMAN Chondrosarcoma-associated gene 2/3 protein (Cancer/testis antigen 24.2) (CT24.2) (Taxol-resistant-associated gene 3 protein) (TRAG-3) CSAG2 TRAG3; CSAG3 CSAG3A Homo sapiens (Human) response to xenobiotic stimulus [GO:0009410] 0.95189 -1.3944 EFYHKTNIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1342 0 0 0 0 0 0 0 Q9Y5Q3 MAFB_HUMAN Transcription factor MafB (Maf-B) (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B) MAFB KRML Homo sapiens (Human) abducens nerve formation [GO:0021599]; brain segmentation [GO:0035284]; cornified envelope assembly [GO:1903575]; fat cell differentiation [GO:0045444]; inner ear morphogenesis [GO:0042472]; integrated stress response signaling [GO:0140467]; keratinocyte differentiation [GO:0030216]; negative regulation of erythrocyte differentiation [GO:0045647]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; protein processing [GO:0016485]; regulation of DNA-templated transcription [GO:0006355]; regulation of myeloid cell differentiation [GO:0045637]; regulation of transcription by RNA polymerase II [GO:0006357]; respiratory gaseous exchange by respiratory system [GO:0007585]; rhombomere 5 development [GO:0021571]; rhombomere 6 development [GO:0021572]; segment specification [GO:0007379]; sensory organ development [GO:0007423]; T cell differentiation in thymus [GO:0033077]; thymus development [GO:0048538] chromatin [GO:0000785]; nucleus [GO:0005634]; RNA polymerase II transcription regulator complex [GO:0090575] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]" 0.88615 -0.33656 GYAQSCRYK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.35929 0 0 Q9Y5Q6 INSL5_HUMAN Insulin-like peptide INSL5 (Insulin-like peptide 5) [Cleaved into: Insulin-like peptide INSL5 B chain; Insulin-like peptide INSL5 A chain] INSL5 UNQ156/PRO182 Homo sapiens (Human) positive regulation of feeding behavior [GO:2000253] extracellular region [GO:0005576] G protein-coupled receptor binding [GO:0001664]; hormone activity [GO:0005179] 0.83358 0.19859 LCGLEYIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.4777 0 0 0 0 0 0 0 0 0 0 0 Q9Y5Q9 TF3C3_HUMAN General transcription factor 3C polypeptide 3 (Transcription factor IIIC 102 kDa subunit) (TFIIIC 102 kDa subunit) (TFIIIC102) (Transcription factor IIIC subunit gamma) (TF3C-gamma) GTF3C3 Homo sapiens (Human) 5S class rRNA transcription by RNA polymerase III [GO:0042791]; transcription by RNA polymerase III [GO:0006383]; tRNA transcription by RNA polymerase III [GO:0042797] fibrillar center [GO:0001650]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; transcription factor TFIIIC complex [GO:0000127] DNA binding [GO:0003677]; RNA polymerase III general transcription initiation factor activity [GO:0000995] 0.90653 -0.71621 LAEMSLEQDNIK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.88218 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y5R5 DMRT2_HUMAN Doublesex- and mab-3-related transcription factor 2 (Doublesex-like 2 protein) (DSXL-2) DMRT2 DSXL2 Homo sapiens (Human) embryonic skeletal system development [GO:0048706]; myotome development [GO:0061055]; positive regulation of myotome development [GO:2000287]; regulation of somitogenesis [GO:0014807]; regulation of transcription by RNA polymerase II [GO:0006357]; sex differentiation [GO:0007548] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.96247 -2.4726 AVYQRQVRAPSLLAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.73207 0 0 0 0 0 0 Q9Y5S2 MRCKB_HUMAN Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (CDC42BP-beta) (DMPK-like beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (MRCK beta) (Myotonic dystrophy protein kinase-like beta) CDC42BPB KIAA1124 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; actomyosin structure organization [GO:0031032]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; establishment or maintenance of cell polarity [GO:0007163]; peptidyl-threonine phosphorylation [GO:0018107]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] actomyosin [GO:0042641]; cell leading edge [GO:0031252]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886] ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674]; protein-containing complex binding [GO:0044877]; small GTPase binding [GO:0031267] 0.96703 -3.706 LEQLLLDGPWR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.50339 0 0 0 10.7579 0 Q9Y5S8 NOX1_HUMAN NADPH oxidase 1 (NOX-1) (EC 1.-.-.-) (Mitogenic oxidase 1) (MOX-1) (NADH/NADPH mitogenic oxidase subunit P65-MOX) (NOH-1) NOX1 MOX1 NOH1 Homo sapiens (Human) angiogenesis [GO:0001525]; cell migration [GO:0016477]; cellular response to hyperoxia [GO:0071455]; cellular stress response to acidic pH [GO:1990451]; defense response [GO:0006952]; extracellular matrix organization [GO:0030198]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; intracellular pH elevation [GO:0051454]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; JNK cascade [GO:0007254]; NADP metabolic process [GO:0006739]; oxygen metabolic process [GO:0072592]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of integrin biosynthetic process [GO:0045726]; positive regulation of JNK cascade [GO:0046330]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of blood pressure [GO:0008217]; regulation of monoatomic ion transmembrane transport [GO:0034765]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; respiratory burst [GO:0045730]; signal transduction [GO:0007165]; superoxide anion generation [GO:0042554] anchoring junction [GO:0070161]; cell projection [GO:0042995]; early endosome [GO:0005769]; NADPH oxidase complex [GO:0043020]; plasma membrane [GO:0005886] metal ion binding [GO:0046872]; NADP binding [GO:0050661]; small GTPase binding [GO:0031267]; superoxide-generating NAD(P)H oxidase activity [GO:0016175]; voltage-gated monoatomic ion channel activity [GO:0005244] 0.96353 -2.2399 CCHRYSSLDPR 9.1641 0 0 0 0 0 0 0 0 0 11.3121 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y5T5 UBP16_HUMAN Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.4.19.12) (Deubiquitinating enzyme 16) (Ubiquitin thioesterase 16) (Ubiquitin-processing protease UBP-M) (Ubiquitin-specific-processing protease 16) USP16 MSTP039 Homo sapiens (Human) cell division [GO:0051301]; DNA damage response [GO:0006974]; histone deubiquitination [GO:0016578]; mitotic nuclear division [GO:0140014]; monoubiquitinated protein deubiquitination [GO:0035520]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of ribosome biogenesis [GO:0090070]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational elongation [GO:0045901]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; regulation of cell cycle [GO:0051726]; regulation of transcription by RNA polymerase II [GO:0006357]; ubiquitin-dependent protein catabolic process [GO:0006511] cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] cysteine-type deubiquitinase activity [GO:0004843]; cysteine-type endopeptidase activity [GO:0004197]; histone binding [GO:0042393]; histone H2A deubiquitinase activity [GO:0140950]; ribosomal small subunit binding [GO:0043024]; transcription coactivator activity [GO:0003713]; ubiquitin binding [GO:0043130]; zinc ion binding [GO:0008270] 0.95909 -1.9554 DNGNIELENKKLEK 11.0992 9.19118 0 0 8.53842 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y5U4 INSI2_HUMAN Insulin-induced gene 2 protein (INSIG-2) INSIG2 Homo sapiens (Human) cellular response to insulin stimulus [GO:0032869]; cholesterol biosynthetic process [GO:0006695]; cranial suture morphogenesis [GO:0060363]; inner ear morphogenesis [GO:0042472]; middle ear morphogenesis [GO:0042474]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of steroid biosynthetic process [GO:0010894]; response to fatty acid [GO:0070542]; roof of mouth development [GO:0060021]; SREBP signaling pathway [GO:0032933]; SREBP-SCAP complex retention in endoplasmic reticulum [GO:0036316]; triglyceride metabolic process [GO:0006641] endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; SREBP-SCAP-Insig complex [GO:0032937] oxysterol binding [GO:0008142]; protein sequestering activity [GO:0140311] 0.92735 -1.2034 VIAEKSHQE 13.0854 0 12.9804 11.6353 0 11.7694 13.2647 13.1666 0 0 0 13.3927 0 11.9507 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y5V3 MAGD1_HUMAN Melanoma-associated antigen D1 (MAGE tumor antigen CCF) (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog) MAGED1 NRAGE PP2250 PRO2292 Homo sapiens (Human) circadian regulation of gene expression [GO:0032922]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of MAP kinase activity [GO:0043406]; protein localization to nucleus [GO:0034504]; regulation of apoptotic process [GO:0042981]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-templated transcription [GO:0006355] chromatin [GO:0000785]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] identical protein binding [GO:0042802]; transcription coactivator activity [GO:0003713] 0.96063 -1.9924 LLTYEFVK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.61442 0 0 0 0 0 0 0 Q9Y5W3 KLF2_HUMAN Krueppel-like factor 2 (Lung krueppel-like factor) KLF2 LKLF Homo sapiens (Human) cell morphogenesis [GO:0000902]; cellular response to cycloheximide [GO:0071409]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to laminar fluid shear stress [GO:0071499]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; cellular stress response to acid chemical [GO:0097533]; epigenetic regulation of gene expression [GO:0040029]; erythrocyte maturation [GO:0043249]; in utero embryonic development [GO:0001701]; multicellular organism growth [GO:0035264]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of sprouting angiogenesis [GO:1903671]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of retinoic acid receptor signaling pathway [GO:0048386]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; regulation of transcription by RNA polymerase II [GO:0006357]; type I pneumocyte differentiation [GO:0060509]; vasodilation [GO:0042311] chromatin [GO:0000785]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.95591 -1.5442 GLQERWPR 0 0 0 0 0 0 0 9.17587 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y5W7 SNX14_HUMAN Sorting nexin-14 SNX14 Homo sapiens (Human) autophagosome maturation [GO:0097352]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein transport [GO:0015031] cytosol [GO:0005829]; dendrite [GO:0030425]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; postsynapse [GO:0098794] "phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]" 0.86271 0.090216 AVGHEPEHWSVYRR 0 0 0 0 0 0 11.5015 0 0 0 0 0 0 10.2055 0 9.36087 0 0 0 0 0 0 0 0 0 0 0 Q9Y5W8 SNX13_HUMAN Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) SNX13 KIAA0713 Homo sapiens (Human) intracellular protein transport [GO:0006886]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547] early endosome [GO:0005769]; early endosome membrane [GO:0031901] phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-3-phosphate binding [GO:0032266] 0.96949 -4.1194 ITEKDDQVK 8.82216 8.92544 0 0 0 0 0 0 0 8.67165 9.21587 9.22217 0 0 0 0 0 9.52391 0 0 0 0 0 0 0 0 0 Q9Y5W9 SNX11_HUMAN Sorting nexin-11 SNX11 Homo sapiens (Human) intracellular protein transport [GO:0006886]; vesicle organization [GO:0016050] endosome [GO:0005768]; membrane [GO:0016020] phosphatidylinositol phosphate binding [GO:1901981] 0.72618 0.35441 GDQPKSCCFLPRSGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.92348 0 0 0 0 0 0 0 0 0 Q9Y5X2 SNX8_HUMAN Sorting nexin-8 SNX8 Homo sapiens (Human) early endosome to Golgi transport [GO:0034498]; intracellular protein transport [GO:0006886] cytosol [GO:0005829]; early endosome membrane [GO:0031901]; intracellular membrane-bounded organelle [GO:0043231] identical protein binding [GO:0042802]; phosphatidylinositol binding [GO:0035091] 0.76488 0.28128 HPLFSEDVVLK 12.9937 12.8503 0 12.6844 0 0 11.8975 12.1743 12.254 0 0 10.9067 0 0 11.2614 0 11.3852 10.574 0 0 0 0 0 0 0 0 0 Q9Y5X3 SNX5_HUMAN Sorting nexin-5 SNX5 Homo sapiens (Human) "epidermal growth factor catabolic process [GO:0007174]; intracellular protein transport [GO:0006886]; negative regulation of blood pressure [GO:0045776]; pinocytosis [GO:0006907]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of renal sodium excretion [GO:0035815]; regulation of macroautophagy [GO:0016241]; retrograde transport, endosome to Golgi [GO:0042147]" "brush border [GO:0005903]; cytoplasmic side of early endosome membrane [GO:0098559]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endosome [GO:0005768]; intracellular membrane-bounded organelle [GO:0043231]; macropinocytic cup [GO:0070685]; perinuclear region of cytoplasm [GO:0048471]; phagocytic cup [GO:0001891]; retromer complex [GO:0030904]; retromer, tubulation complex [GO:0030905]; ruffle [GO:0001726]; tubular endosome [GO:0097422]" "cadherin binding [GO:0045296]; D1 dopamine receptor binding [GO:0031748]; dynactin binding [GO:0034452]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]" 0.72593 0.34752 LAEAHQQECCQK 0 9.41971 0 0 0 0 0 9.20026 0 11.0106 11.0713 11.1248 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y5X4 NR2E3_HUMAN Photoreceptor-specific nuclear receptor (Nuclear receptor subfamily 2 group E member 3) (Retina-specific nuclear receptor) NR2E3 PNR RNR Homo sapiens (Human) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; eye photoreceptor cell development [GO:0042462]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phototransduction [GO:0007602]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; visual perception [GO:0007601] nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription regulator complex [GO:0005667] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; nuclear receptor activity [GO:0004879]; nuclear steroid receptor activity [GO:0003707]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]" 0.92345 -1.0724 TIGNTPMEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.21922 0 0 0 10.6321 0 0 Q9Y5X5 NPFF2_HUMAN Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77) (Neuropeptide G-protein coupled receptor) NPFFR2 GPR74 NPFF2 NPGPR Homo sapiens (Human) cellular response to hormone stimulus [GO:0032870]; detection of abiotic stimulus [GO:0009582]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] actin cytoskeleton [GO:0015629]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; neuropeptide receptor activity [GO:0008188]; opioid receptor binding [GO:0031628]; peptide binding [GO:0042277] 0.96743 -2.8235 DRTCCCR 0 0 0 0 0 0 10.996 0 0 0 0 0 0 0 0 0 0 0 0 9.38524 0 0 0 0 0 0 0 Q9Y5X9 LIPE_HUMAN Endothelial lipase (EC 3.1.1.3) (Endothelial cell-derived lipase) (EDL) (EL) (Phospholipase A1) (EC 3.1.1.32) LIPG UNQ387/PRO719 Homo sapiens (Human) cell population proliferation [GO:0008283]; cholesterol homeostasis [GO:0042632]; high-density lipoprotein particle remodeling [GO:0034375]; lipid catabolic process [GO:0016042]; lipid metabolic process [GO:0006629]; phospholipid catabolic process [GO:0009395]; phospholipid homeostasis [GO:0055091]; positive regulation of cholesterol transport [GO:0032376]; positive regulation of high-density lipoprotein particle clearance [GO:0010983]; regulation of lipoprotein metabolic process [GO:0050746]; response to nutrient [GO:0007584]; reverse cholesterol transport [GO:0043691] cell surface [GO:0009986]; early endosome [GO:0005769]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794] 1-acyl-2-lysophosphatidylserine acylhydrolase activity [GO:0052740]; heparin binding [GO:0008201]; lipase activity [GO:0016298]; lipoprotein lipase activity [GO:0004465]; phosphatidylserine 1-acylhydrolase activity [GO:0052739]; phospholipase A1 activity [GO:0008970]; phospholipase activity [GO:0004620]; triglyceride lipase activity [GO:0004806] 0.93191 -1.2743 KNRCNSIGYNAK 0 0 0 0 0 0 9.65684 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y5Y2 NUBP2_HUMAN Cytosolic Fe-S cluster assembly factor NUBP2 (Nucleotide-binding protein 2) (NBP 2) NUBP2 Homo sapiens (Human) cell projection organization [GO:0030030]; iron-sulfur cluster assembly [GO:0016226] centriole [GO:0005814]; cilium [GO:0005929]; cytosol [GO:0005829]; nucleus [GO:0005634]; spindle pole centrosome [GO:0031616] "4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; ATP-dependent FeS chaperone activity [GO:0140663]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]" 0.9588 -1.7003 ELTFCRK 0 0 0 0 11.546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y5Y4 PD2R2_HUMAN Prostaglandin D2 receptor 2 (Chemoattractant receptor-homologous molecule expressed on Th2 cells) (G-protein coupled receptor 44) (CD antigen CD294) PTGDR2 CRTH2 DL1R GPR44 Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; calcium-mediated signaling [GO:0019722]; chemotaxis [GO:0006935]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; negative regulation of male germ cell proliferation [GO:2000255]; neuropeptide signaling pathway [GO:0007218]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745] neuron projection [GO:0043005]; plasma membrane [GO:0005886] G protein-coupled receptor activity [GO:0004930]; prostaglandin D receptor activity [GO:0004956]; prostaglandin F receptor activity [GO:0004958]; prostaglandin J receptor activity [GO:0001785] 0.67172 0.39371 ALSSTSS 0 9.54711 0 0 0 0 0 0 0 0 0 0 9.30681 9.35867 9.30234 0 0 0 9.27908 0 0 0 0 0 0 0 0 Q9Y5Y6 ST14_HUMAN Suppressor of tumorigenicity 14 protein (EC 3.4.21.109) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease 14) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein) ST14 PRSS14 SNC19 TADG15 Homo sapiens (Human) epithelial cell morphogenesis involved in placental branching [GO:0060672]; keratinocyte differentiation [GO:0030216]; neural tube closure [GO:0001843]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508] basolateral plasma membrane [GO:0016323]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236] 0.97021 -3.2889 DCDCGLRSFTR 0 0 0 9.67048 9.71595 9.83692 0 0 0 10.4267 0 0 0 0 0 0 0 0 0 0 0 10.2244 0 0 0 0 0 Q9Y5Y7 LYVE1_HUMAN Lymphatic vessel endothelial hyaluronic acid receptor 1 (LYVE-1) (Cell surface retention sequence-binding protein 1) (CRSBP-1) (Extracellular link domain-containing protein 1) (Hyaluronic acid receptor) LYVE1 CRSBP1 HAR XLKD1 UNQ230/PRO263 Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; cell-matrix adhesion [GO:0007160]; hyaluronan catabolic process [GO:0030214]; positive regulation of cellular extravasation [GO:0002693]; receptor-mediated endocytosis [GO:0006898]; response to wounding [GO:0009611] extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886] cargo receptor activity [GO:0038024]; hyaluronic acid binding [GO:0005540]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888] 0.77342 0.26674 AEELSIQVSCR 0 0 0 0 0 0 10.0626 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y5Y9 SCNAA_HUMAN Sodium channel protein type 10 subunit alpha (Peripheral nerve sodium channel 3) (PN3) (hPN3) (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) SCN10A Homo sapiens (Human) AV node cell action potential [GO:0086016]; bundle of His cell action potential [GO:0086043]; calcium ion import across plasma membrane [GO:0098703]; odontogenesis of dentin-containing tooth [GO:0042475]; regulation of atrial cardiac muscle cell membrane depolarization [GO:0060371]; regulation of cardiac muscle contraction [GO:0055117]; regulation of heart rate [GO:0002027]; regulation of monoatomic ion transmembrane transport [GO:0034765]; sensory perception [GO:0007600]; sensory perception of pain [GO:0019233]; sodium ion transmembrane transport [GO:0035725] axon [GO:0030424]; clathrin complex [GO:0071439]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; presynaptic membrane [GO:0042734]; voltage-gated calcium channel complex [GO:0005891]; voltage-gated sodium channel complex [GO:0001518] high voltage-gated calcium channel activity [GO:0008331]; transmembrane transporter binding [GO:0044325]; voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential [GO:0099508]; voltage-gated sodium channel activity [GO:0005248] 0.897 -0.67677 GRTISRFSATR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.95487 0 0 0 0 0 0 0 0 0 0 Q9Y5Z0 BACE2_HUMAN Beta-secretase 2 (EC 3.4.23.45) (Aspartic-like protease 56 kDa) (Aspartyl protease 1) (ASP1) (Asp 1) (Beta-site amyloid precursor protein cleaving enzyme 2) (Beta-site APP cleaving enzyme 2) (Down region aspartic protease) (DRAP) (Memapsin-1) (Membrane-associated aspartic protease 1) (Theta-secretase) BACE2 AEPLC ALP56 ASP21 CDA13 UNQ418/PRO852 Homo sapiens (Human) amyloid-beta metabolic process [GO:0050435]; glucose homeostasis [GO:0042593]; melanosome organization [GO:0032438]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein processing [GO:0016485]; proteolysis [GO:0006508] endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; melanosome membrane [GO:0033162]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802] aspartic-type endopeptidase activity [GO:0004190] 0.96276 -2.5015 DPEVVNDESSLVRHR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.28522 0 Q9Y5Z4 HEBP2_HUMAN Heme-binding protein 2 (Placental protein 23) (PP23) (Protein SOUL) HEBP2 C6orf34 SOUL Homo sapiens (Human) negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940] azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; mitochondrion [GO:0005739] heme binding [GO:0020037] 0.95952 -1.9098 LNSYIQGKNEK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9196 0 0 0 0 0 0 0 0 0 9.81916 Q9Y5Z7 HCFC2_HUMAN Host cell factor 2 (HCF-2) (C2 factor) HCFC2 Homo sapiens (Human) chromatin remodeling [GO:0006338]; histone H3-K4 methylation [GO:0051568]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; viral process [GO:0016032] cytoplasm [GO:0005737]; cytosol [GO:0005829]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL1/2 complex [GO:0044665]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; Set1C/COMPASS complex [GO:0048188] transcription coactivator activity [GO:0003713] 0.52247 0.58855 ILVFGGMVEYGR 0 0 0 10.0761 0 0 0 0 0 0 0 0 0 0 0 0 0 9.94297 0 0 0 0 0 0 0 10.6584 0 Q9Y605 MOFA1_HUMAN MORF4 family-associated protein 1 (Protein PGR1) (Protein associated with MRG of 14 kDa) MRFAP1 PAM14 PGR1 Homo sapiens (Human) nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471] 0.80806 0.22831 LWEMDNMLIQIK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.57786 0 0 0 0 Q9Y608 LRRF2_HUMAN Leucine-rich repeat flightless-interacting protein 2 (LRR FLII-interacting protein 2) LRRFIP2 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; Wnt signaling pathway [GO:0016055] LRR domain binding [GO:0030275] 0.93252 -1.2594 IEEMEMTNSHLAK 0 0 0 9.59872 0 0 0 0 0 10.9388 0 0 0 0 0 0 0 0 0 0 0 0 9.49079 0 0 0 0 Q9Y613 FHOD1_HUMAN FH1/FH2 domain-containing protein 1 (Formin homolog overexpressed in spleen 1) (FHOS) (Formin homology 2 domain-containing protein 1) FHOD1 FHOS FHOS1 Homo sapiens (Human) cortical actin cytoskeleton organization [GO:0030866]; establishment of centrosome localization [GO:0051660]; nuclear migration [GO:0007097]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of stress fiber assembly [GO:0051492] bleb [GO:0032059]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; intercalated disc [GO:0014704]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] actin filament binding [GO:0051015]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein self-association [GO:0043621] 0.95903 -1.8321 EFALEYR 0 0 0 0 0 0 0 0 11.2637 0 0 0 9.96142 0 8.74315 0 0 10.5069 0 0 0 9.1158 0 0 0 0 0 Q9Y617 SERC_HUMAN Phosphoserine aminotransferase (EC 2.6.1.52) (Phosphohydroxythreonine aminotransferase) (PSAT) PSAT1 PSA Homo sapiens (Human) L-serine biosynthetic process [GO:0006564]; pyridoxine biosynthetic process [GO:0008615] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062] identical protein binding [GO:0042802]; O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170] 0.9566 -1.5423 CADYVVTGAWSAK 0 9.0477 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.54961 Q9Y618 NCOR2_HUMAN "Nuclear receptor corepressor 2 (N-CoR2) (CTG repeat protein 26) (SMAP270) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (T3 receptor-associating factor) (TRAC) (Thyroid-, retinoic-acid-receptor-associated corepressor)" NCOR2 CTG26 Homo sapiens (Human) cerebellum development [GO:0021549]; estrous cycle [GO:0044849]; lactation [GO:0007595]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of miRNA transcription [GO:1902894]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of cellular ketone metabolic process [GO:0010565]; response to estradiol [GO:0032355]; response to organonitrogen compound [GO:0010243] chromatin [GO:0000785]; membrane [GO:0016020]; nuclear body [GO:0016604]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription repressor complex [GO:0017053] chromatin binding [GO:0003682]; DNA binding [GO:0003677]; histone deacetylase binding [GO:0042826]; Notch binding [GO:0005112]; nuclear glucocorticoid receptor binding [GO:0035259]; nuclear retinoid X receptor binding [GO:0046965]; protein-containing complex binding [GO:0044877]; transcription corepressor activity [GO:0003714] 0.95193 -1.4462 HSPHHLK 0 9.88339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.53687 0 0 0 0 10.0172 0 0 0 Q9Y620 RA54B_HUMAN DNA repair and recombination protein RAD54B (EC 3.6.4.-) (RAD54 homolog B) RAD54B Homo sapiens (Human) determination of adult lifespan [GO:0008340]; double-strand break repair via homologous recombination [GO:0000724]; mitotic recombination [GO:0006312]; reciprocal meiotic recombination [GO:0007131]; response to ionizing radiation [GO:0010212]; response to xenobiotic stimulus [GO:0009410] nucleus [GO:0005634] ATP binding [GO:0005524]; ATP-dependent chromatin remodeler activity [GO:0140658]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; DNA translocase activity [GO:0015616]; hydrolase activity [GO:0016787]; RNA helicase activity [GO:0003724] 0.95968 -1.9031 EVAVSKEQEEK 0 12.9887 0 0 9.82003 12.4732 8.55244 12.862 12.8987 11.6217 0 9.59384 0 0 0 13.1286 0 0 0 0 0 0 0 0 0 0 0 Q9Y623 MYH4_HUMAN "Myosin-4 (Myosin heavy chain 2b) (MyHC-2b) (Myosin heavy chain 4) (Myosin heavy chain IIb) (MyHC-IIb) (Myosin heavy chain, skeletal muscle, fetal)" MYH4 Homo sapiens (Human) actin filament-based movement [GO:0030048]; ATP metabolic process [GO:0046034]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049] cytoplasm [GO:0005737]; muscle myosin complex [GO:0005859]; myofibril [GO:0030016]; myosin filament [GO:0032982]; myosin II complex [GO:0016460]; sarcomere [GO:0030017] actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; calmodulin binding [GO:0005516]; double-stranded RNA binding [GO:0003725]; microfilament motor activity [GO:0000146] 0.96103 -2.0594 ADIAESQVNK 0 0 0 0 9.44555 0 0 0 0 0 0 0 0 10.1896 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y624 JAM1_HUMAN Junctional adhesion molecule A (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet F11 receptor) (Platelet adhesion molecule 1) (PAM-1) (CD antigen CD321) F11R JAM1 JCAM UNQ264/PRO301 Homo sapiens (Human) actomyosin structure organization [GO:0031032]; cell-cell adhesion [GO:0098609]; cellular response to mechanical stimulus [GO:0071260]; establishment of endothelial intestinal barrier [GO:0090557]; inflammatory response [GO:0006954]; intestinal absorption [GO:0050892]; leukocyte cell-cell adhesion [GO:0007159]; maintenance of blood-brain barrier [GO:0035633]; memory T cell extravasation [GO:0035683]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of platelet aggregation [GO:1901731]; positive regulation of Rho protein signal transduction [GO:0035025]; protein localization to bicellular tight junction [GO:1902396]; protein localization to plasma membrane [GO:0072659]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cell shape [GO:0008360]; regulation of cytokine production [GO:0001817]; regulation of cytoskeleton organization [GO:0051493]; regulation of membrane permeability [GO:0090559] bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cell-cell junction [GO:0005911]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; tight junction [GO:0070160] cadherin binding [GO:0045296]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; virus receptor activity [GO:0001618] 0.96847 -3.3536 DGIVMPTNPK 0 0 0 0 0 0 0 0 0 9.14759 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y625 GPC6_HUMAN Glypican-6 [Cleaved into: Secreted glypican-6] GPC6 UNQ369/PRO705 Homo sapiens (Human) cell migration [GO:0016477]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of signal transduction [GO:0009966] cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; lysosomal lumen [GO:0043202]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202] "coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway [GO:1904929]" 0.96396 -2.394 LEFENLVEETSHFVR 0 9.49349 9.23912 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y639 NPTN_HUMAN Neuroplastin (Stromal cell-derived receptor 1) (SDR-1) NPTN SDFR1 SDR1 Homo sapiens (Human) "excitatory synapse assembly [GO:1904861]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intracellular calcium ion homeostasis [GO:0006874]; long-term synaptic potentiation [GO:0060291]; negative regulation of cytokine production [GO:0001818]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein localization [GO:1903829]; positive regulation of protein phosphorylation [GO:0001934]; regulation of receptor localization to synapse [GO:1902683]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; visual learning [GO:0008542]" cell surface [GO:0009986]; dendrite [GO:0030425]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; inhibitory synapse [GO:0060077]; postsynaptic density membrane [GO:0098839]; presynaptic active zone membrane [GO:0048787]; presynaptic membrane [GO:0042734]; Schaffer collateral - CA1 synapse [GO:0098685] cell adhesion molecule binding [GO:0050839]; transmembrane transporter binding [GO:0044325]; type 1 fibroblast growth factor receptor binding [GO:0005105] 0.94084 -1.3167 NLRQRNTN 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.54824 0 0 0 0 Q9Y644 RFNG_HUMAN "Beta-1,3-N-acetylglucosaminyltransferase radical fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase)" RFNG Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell differentiation [GO:0030154]; nervous system development [GO:0007399]; pattern specification process [GO:0007389]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of protein binding [GO:0032092]; regulation of Notch signaling pathway [GO:0008593] extracellular region [GO:0005576]; Golgi membrane [GO:0000139] metal ion binding [GO:0046872]; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity [GO:0033829] 0.82276 0.21714 VINTNCSAVR 0 0 8.72605 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y646 CBPQ_HUMAN Carboxypeptidase Q (EC 3.4.17.-) (Lysosomal dipeptidase) (Plasma glutamate carboxypeptidase) CPQ LCH1 PGCP Homo sapiens (Human) peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]; thyroid hormone generation [GO:0006590]; tissue regeneration [GO:0042246] cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764] carboxypeptidase activity [GO:0004180]; metal ion binding [GO:0046872]; metallodipeptidase activity [GO:0070573]; protein homodimerization activity [GO:0042803] 0.96362 -2.1124 IPHWERGEESAVMLEPR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.4584 0 0 0 0 0 0 0 0 0 0 Q9Y657 SPIN1_HUMAN Spindlin-1 (Ovarian cancer-related protein) (Spindlin1) SPIN1 OCR SPIN Homo sapiens (Human) chromatin organization [GO:0006325]; gamete generation [GO:0007276]; meiotic cell cycle [GO:0051321]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of DNA-templated transcription [GO:0006355]; rRNA transcription [GO:0009303]; Wnt signaling pathway [GO:0016055] cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819] methylated histone binding [GO:0035064] 0.89703 -0.53323 AVEHMFETEDGSK 0 0 0 0 0 0 0 12.0849 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y661 HS3S4_HUMAN Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (3-OST-4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4) HS3ST4 3OST4 Homo sapiens (Human) heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparan sulfate proteoglycan metabolic process [GO:0030201] Golgi membrane [GO:0000139] [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity [GO:0008467] 0.78104 0.26164 LIVDPAGEMAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.2436 0 0 0 0 0 0 0 0 0 0 0 Q9Y666 S12A7_HUMAN Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4) SLC12A7 KCC4 Homo sapiens (Human) ammonium import across plasma membrane [GO:0140157]; cell volume homeostasis [GO:0006884]; cellular response to glucose stimulus [GO:0071333]; chemical synaptic transmission [GO:0007268]; chloride ion homeostasis [GO:0055064]; chloride transmembrane transport [GO:1902476]; monoatomic ion transport [GO:0006811]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805] plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202] ammonium transmembrane transporter activity [GO:0008519]; potassium:chloride symporter activity [GO:0015379]; protein kinase binding [GO:0019901] 0.88312 -0.11131 EAQLIHDR 0 10.9313 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y678 COPG1_HUMAN Coatomer subunit gamma-1 (Gamma-1-coat protein) (Gamma-1-COP) COPG1 COPG Homo sapiens (Human) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; establishment of Golgi localization [GO:0051683]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; organelle transport along microtubule [GO:0072384]; protein secretion [GO:0009306] COPI vesicle coat [GO:0030126]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; transport vesicle [GO:0030133] structural molecule activity [GO:0005198] 0 9.856 AGAVSALAK 0 0 0 0 0 8.60173 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3487 0 0 0 0 10.6495 0 11.01 Q9Y679 AUP1_HUMAN Lipid droplet-regulating VLDL assembly factor AUP1 (Ancient ubiquitous protein 1) AUP1 Homo sapiens (Human) "ER-associated misfolded protein catabolic process [GO:0071712]; lipid droplet formation [GO:0140042]; lipid droplet organization [GO:0034389]; lipophagy [GO:0061724]; protein localization to lipid droplet [GO:1990044]; response to virus [GO:0009615]; retrograde protein transport, ER to cytosol [GO:0030970]; ubiquitin-dependent ERAD pathway [GO:0030433]" autophagosome [GO:0005776]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; membrane [GO:0016020] ubiquitin binding [GO:0043130]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625] 0.94068 -1.3294 AEHMKRQR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5945 0 0 0 0 0 0 0 0 0 Q9Y692 GMEB1_HUMAN Glucocorticoid modulatory element-binding protein 1 (GMEB-1) (DNA-binding protein p96PIF) (Parvovirus initiation factor p96) (PIF p96) GMEB1 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; Hsp27 protein binding [GO:0051008]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]" 0.80901 0.23214 FNDQLISPK 0 0 0 0 0 0 0 0 0 0 0 0 9.90941 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y697 NFS1_HUMAN Cysteine desulfurase (EC 2.8.1.7) NFS1 NIFS HUSSY-08 Homo sapiens (Human) [2Fe-2S] cluster assembly [GO:0044571]; [4Fe-4S] cluster assembly [GO:0044572]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdopterin cofactor metabolic process [GO:0043545] cytosol [GO:0005829]; iron-sulfur cluster assembly complex [GO:1990229]; mitochondrial iron-sulfur cluster assembly complex [GO:0099128]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] cysteine desulfurase activity [GO:0031071]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170] 0.92281 -1.058 KKHLITTQTEHK 0 0 0 0 0 0 0 0 8.75512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y698 CCG2_HUMAN Voltage-dependent calcium channel gamma-2 subunit (Neuronal voltage-gated calcium channel gamma-2 subunit) (Transmembrane AMPAR regulatory protein gamma-2) (TARP gamma-2) CACNG2 Homo sapiens (Human) "eye blink reflex [GO:0060082]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; neuromuscular junction development [GO:0007528]; neurotransmitter receptor internalization [GO:0099590]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; neurotransmitter receptor transport, postsynaptic endosome to lysosome [GO:0098943]; positive regulation of AMPA receptor activity [GO:2000969]; positive regulation of protein localization to basolateral plasma membrane [GO:1904510]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein targeting to membrane [GO:0006612]; regulation of AMPA receptor activity [GO:2000311]; response to calcium ion [GO:0051592]; transmission of nerve impulse [GO:0019226]" AMPA glutamate receptor complex [GO:0032281]; cell surface [GO:0009986]; cerebellar mossy fiber [GO:0044300]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; Schaffer collateral - CA1 synapse [GO:0098685]; somatodendritic compartment [GO:0036477]; voltage-gated calcium channel complex [GO:0005891] channel regulator activity [GO:0016247]; ionotropic glutamate receptor binding [GO:0035255]; voltage-gated calcium channel activity [GO:0005245] 0.88226 -0.073916 DNSFLQVHNCIQKENK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0934 9.5461 0 0 0 0 0 0 0 8.70508 Q9Y6A1 POMT1_HUMAN Protein O-mannosyl-transferase 1 (EC 2.4.1.109) (Dolichyl-phosphate-mannose--protein mannosyltransferase 1) POMT1 Homo sapiens (Human) extracellular matrix organization [GO:0030198]; positive regulation of protein O-linked glycosylation [GO:1904100]; protein O-linked glycosylation [GO:0006493]; protein O-linked mannosylation [GO:0035269] acrosomal vesicle [GO:0001669]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; sarcoplasmic reticulum [GO:0016529] dolichyl-phosphate-mannose-protein mannosyltransferase activity [GO:0004169]; mannosyltransferase activity [GO:0000030]; metal ion binding [GO:0046872] 0.85068 0.15967 IGAEYSSNVPVWSLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.90938 0 0 0 0 0 Q9Y6A4 CFA20_HUMAN Cilia- and flagella-associated protein 20 (Basal body up-regulated protein 22) (Transcription factor IIB) CFAP20 BUG22 C16orf80 GTL3 Homo sapiens (Human) cilium assembly [GO:0060271]; positive regulation of cell motility [GO:2000147]; positive regulation of feeding behavior [GO:2000253]; protein polyglutamylation [GO:0018095]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296] axonemal microtubule [GO:0005879]; centriole [GO:0005814]; ciliary basal body [GO:0036064]; cilium [GO:0005929]; extracellular exosome [GO:0070062]; motile cilium [GO:0031514]; nucleoplasm [GO:0005654] RNA binding [GO:0003723] 0.89774 -0.56402 KYFTFEVQVLDDK 0 0 0 0 0 0 0 0 0 0 10.2966 0 0 0 0 0 0 8.43095 0 0 0 0 0 0 0 0 0 Q9Y6A5 TACC3_HUMAN Transforming acidic coiled-coil-containing protein 3 (ERIC-1) TACC3 ERIC1 Homo sapiens (Human) cell division [GO:0051301]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; microtubule cytoskeleton organization [GO:0000226]; microtubule cytoskeleton organization involved in mitosis [GO:1902850]; mitotic spindle organization [GO:0007052]; regulation of mitotic spindle organization [GO:0060236] centriolar satellite [GO:0034451]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitotic spindle [GO:0072686]; spindle pole [GO:0000922] 0.88212 -0.023226 ICDDLISK 0 0 0 0 0 0 0 0 0 10.0077 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.5067 0 Q9Y6C2 EMIL1_HUMAN EMILIN-1 (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1) EMILIN1 EMI Homo sapiens (Human) aortic valve morphogenesis [GO:0003180]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; elastic fiber assembly [GO:0048251]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell activation [GO:0050866]; negative regulation of cell migration [GO:0030336]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of collagen fibril organization [GO:1904027]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of gene expression [GO:0010629]; negative regulation of macrophage migration [GO:1905522]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of extracellular matrix assembly [GO:1901203]; positive regulation of gene expression [GO:0010628]; positive regulation of platelet aggregation [GO:1901731]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127] collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; EMILIN complex [GO:1990971]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integrin alpha4-beta1 complex [GO:0034668] extracellular matrix constituent conferring elasticity [GO:0030023]; identical protein binding [GO:0042802]; integrin binding involved in cell-matrix adhesion [GO:0098640]; molecular adaptor activity [GO:0060090] 0.83236 0.20111 LHQLSLK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.98391 0 0 0 Q9Y6C5 PTC2_HUMAN Protein patched homolog 2 (PTC2) PTCH2 UNQ560/PRO1121/PRO57079 Homo sapiens (Human) cell fate determination [GO:0001709]; epidermal cell fate specification [GO:0009957]; hair cycle [GO:0042633]; negative regulation of smoothened signaling pathway [GO:0045879]; positive regulation of epidermal cell differentiation [GO:0045606]; regulation of cell growth [GO:0001558]; skin development [GO:0043588] plasma membrane [GO:0005886] hedgehog family protein binding [GO:0097108]; hedgehog receptor activity [GO:0008158]; smoothened binding [GO:0005119] 0.86454 0.084419 DPQGELLR 0 0 7.83681 8.42949 0 0 0 0 0 0 15.4675 9.00459 0 0 0 0 0 0 0 9.78821 0 9.21386 10.0921 0 10.9601 0 9.34256 Q9Y6C9 MTCH2_HUMAN Mitochondrial carrier homolog 2 (Met-induced mitochondrial protein) MTCH2 MIMP HSPC032 Homo sapiens (Human) lipid homeostasis [GO:0055088]; positive regulation of apoptotic process [GO:0043065]; positive regulation of stem cell differentiation [GO:2000738]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein localization to mitochondrion [GO:0070585]; regulation of mitochondrial fusion [GO:0010635] membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleus [GO:0005634] membrane insertase activity [GO:0032977] 0.88364 -0.17252 GLFTGLTPR 0 0 0 0 9.76575 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y6D5 BIG2_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2) (ADP-ribosylation factor guanine nucleotide-exchange factor 2) ARFGEF2 ARFGEP2 BIG2 Homo sapiens (Human) endomembrane system organization [GO:0010256]; endosome organization [GO:0007032]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; intracellular signal transduction [GO:0035556]; positive regulation of tumor necrosis factor production [GO:0032760]; protein transport [GO:0015031]; receptor recycling [GO:0001881]; regulation of ARF protein signal transduction [GO:0032012] asymmetric synapse [GO:0032279]; axonemal microtubule [GO:0005879]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; perinuclear region of cytoplasm [GO:0048471]; presynapse [GO:0098793]; recycling endosome [GO:0055037]; symmetric synapse [GO:0032280]; trans-Golgi network [GO:0005802] GABA receptor binding [GO:0050811]; guanyl-nucleotide exchange factor activity [GO:0005085]; myosin binding [GO:0017022]; protein kinase A regulatory subunit binding [GO:0034237] 0.96996 -4.3886 DFLRPFEHIMKK 0 0 10.576 0 0 0 0 10.733 0 0 0 0 0 0 0 0 0 0 0 0 0 9.78395 10.4884 0 0 0 0 Q9Y6D6 BIG1_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (ADP-ribosylation factor guanine nucleotide-exchange factor 1) (p200 ARF guanine nucleotide exchange factor) (p200 ARF-GEP1) ARFGEF1 ARFGEP1 BIG1 Homo sapiens (Human) endomembrane system organization [GO:0010256]; exocytosis [GO:0006887]; Golgi organization [GO:0007030]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of GTPase activity [GO:0034260]; positive regulation of wound healing [GO:0090303]; protein glycosylation [GO:0006486]; protein transport [GO:0015031]; regulation of ARF protein signal transduction [GO:0032012]; regulation of establishment of cell polarity [GO:2000114] cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; small nuclear ribonucleoprotein complex [GO:0030532]; trans-Golgi network [GO:0005802] guanyl-nucleotide exchange factor activity [GO:0005085]; myosin binding [GO:0017022]; protein kinase A regulatory subunit binding [GO:0034237] 0.88386 -0.3169 EQYIKMNR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.96162 0 0 0 0 0 0 0 0 Q9Y6D9 MD1L1_HUMAN Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient 1-like protein 1) (MAD1-like protein 1) (Mitotic checkpoint MAD1 protein homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181) MAD1L1 MAD1 TXBP181 Homo sapiens (Human) attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; cell division [GO:0051301]; cytoplasmic sequestering of protein [GO:0051220]; deactivation of mitotic spindle assembly checkpoint [GO:1902426]; mitotic spindle assembly checkpoint signaling [GO:0007094]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; regulation of metaphase plate congression [GO:0090235]; thymus development [GO:0048538] centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; MAD1 complex [GO:1990706]; mitotic spindle [GO:0072686]; mitotic spindle assembly checkpoint MAD1-MAD2 complex [GO:1990728]; nuclear pore nuclear basket [GO:0044615]; nucleus [GO:0005634]; spindle [GO:0005819]; spindle pole [GO:0000922] identical protein binding [GO:0042802]; kinetochore binding [GO:0043515] 0.96956 -3.4381 AEQIRSKSHLIQVER 9.46483 0 0 0 0 0 0 0 0 0 14.8619 0 8.96924 0 10.4262 0 0 9.50647 0 0 0 9.96513 0 8.91064 0 0 0 Q9Y6E0 STK24_HUMAN Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) (MST-3) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 36 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)] STK24 MST3 STK3 Homo sapiens (Human) cellular response to starvation [GO:0009267]; execution phase of apoptosis [GO:0097194]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; negative regulation of cell migration [GO:0030336]; positive regulation of axon regeneration [GO:0048680]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axon regeneration [GO:0048679]; response to hydrogen peroxide [GO:0042542]; signal transduction [GO:0007165] cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; cadherin binding [GO:0045296]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein serine/threonine kinase activity [GO:0004674] 0.95551 -1.6387 DPKNLENGALQPSDLDR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.3749 0 0 0 Q9Y6E2 5MP1_HUMAN eIF5-mimic protein 1 (Basic leucine zipper and W2 domain-containing protein 2) BZW2 5MP1 HSPC028 MSTP017 Homo sapiens (Human) regulation of translational initiation [GO:0006446] cytoplasm [GO:0005737]; membrane [GO:0016020] cadherin binding [GO:0045296] 0.88224 -0.021921 DANSVTSSLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.43421 0 Q9Y6F1 PARP3_HUMAN Protein mono-ADP-ribosyltransferase PARP3 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 3) (ARTD3) (DNA ADP-ribosyltransferase PARP3) (EC 2.4.2.-) (IRT1) (NAD(+) ADP-ribosyltransferase 3) (ADPRT-3) (Poly [ADP-ribose] polymerase 3) (PARP-3) (hPARP-3) (Poly[ADP-ribose] synthase 3) (pADPRT-3) PARP3 ADPRT3 ADPRTL3 Homo sapiens (Human) DNA ADP-ribosylation [GO:0030592]; double-strand break repair [GO:0006302]; negative regulation of isotype switching [GO:0045829]; negative regulation of telomerase RNA reverse transcriptase activity [GO:1905662]; positive regulation of DNA ligation [GO:0051106]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to site of double-strand break [GO:1990166]; regulation of mitotic spindle organization [GO:0060236]; telomere maintenance [GO:0000723] centriole [GO:0005814]; cytoplasm [GO:0005737]; intercellular bridge [GO:0045171]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; site of double-strand break [GO:0035861] catalytic activity [GO:0003824]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+- protein-aspartate ADP-ribosyltransferase activity [GO:0140806]; NAD+- protein-lysine ADP-ribosyltransferase activity [GO:0140804]; NAD+-protein ADP-ribosyltransferase activity [GO:1990404]; NAD+-protein-glutamate ADP-ribosyltransferase activity [GO:0140807]; nucleotidyltransferase activity [GO:0016779] 0.93965 -1.3184 LSKQQIAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.1583 0 0 0 0 0 0 0 0 0 0 Q9Y6F6 IRAG1_HUMAN "Inositol 1,4,5-triphosphate receptor associated 1 (Inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate) (JAW1-related protein MRVI1) (Protein MRVI1)" IRAG1 IRAG JAW1L MRVI1 Homo sapiens (Human) cGMP-mediated signaling [GO:0019934] endoplasmic reticulum membrane [GO:0005789]; perinuclear region of cytoplasm [GO:0048471]; platelet dense tubular network membrane [GO:0031095]; sarcoplasmic reticulum [GO:0016529] 0.95076 -1.4167 ARMEEEAYSK 0 10.2002 0 0 0 0 10.3318 0 0 8.03952 10.7415 0 0 10.5757 0 9.62496 0 0 0 0 0 0 0 0 0 0 0 Q9Y6F7 CDY2_HUMAN Testis-specific chromodomain protein Y 2 (EC 2.3.1.48) CDY2A CDY2; CDY2B Homo sapiens (Human) spermatogenesis [GO:0007283] nucleus [GO:0005634] histone acetyltransferase activity [GO:0004402]; transcription corepressor activity [GO:0003714] 0.91841 -0.85605 LTAREACAK 0 8.63713 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.83428 8.52489 0 0 0 8.15745 0 0 0 Q9Y6F9 WNT6_HUMAN Protein Wnt-6 WNT6 Homo sapiens (Human) axis specification [GO:0009798]; branching involved in ureteric bud morphogenesis [GO:0001658]; canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cornea development in camera-type eye [GO:0061303]; epithelial-mesenchymal cell signaling [GO:0060684]; nephron tubule formation [GO:0072079]; neuron differentiation [GO:0030182]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of tooth mineralization [GO:0070172] cell surface [GO:0009986]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886] cytokine activity [GO:0005125]; frizzled binding [GO:0005109] 0.96707 -3.7687 GARLGVR 0 0 8.82861 0 0 0 0 0 0 9.1395 9.47202 9.07079 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y6G5 COMDA_HUMAN COMM domain-containing protein 10 COMMD10 HSPC305 PTD002 Homo sapiens (Human) cytoplasm [GO:0005737]; nucleoplasm [GO:0005654] 0.70119 0.37239 VLVEFSHK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.19695 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y6G9 DC1L1_HUMAN "Cytoplasmic dynein 1 light intermediate chain 1 (LIC1) (Dynein light chain A) (DLC-A) (Dynein light intermediate chain 1, cytosolic)" DYNC1LI1 DNCLI1 Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based movement [GO:0007018]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267] centrosome [GO:0005813]; cytoplasmic dynein complex [GO:0005868]; cytosol [GO:0005829]; ficolin-1-rich granule membrane [GO:0101003]; kinetochore [GO:0000776]; membrane [GO:0016020]; microtubule [GO:0005874]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spindle pole [GO:0000922] ATP binding [GO:0005524]; dynein heavy chain binding [GO:0045504]; GDP binding [GO:0019003]; molecular adaptor activity [GO:0060090]; RNA binding [GO:0003723] 0.80146 0.23936 DAVFIPAGWDNDK 0 0 0 0 0 0 0 0 0 0 0 0 0 9.67103 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y6H5 SNCAP_HUMAN Synphilin-1 (Sph1) (Alpha-synuclein-interacting protein) SNCAIP Homo sapiens (Human) cell death [GO:0008219]; dopamine metabolic process [GO:0042417]; regulation of inclusion body assembly [GO:0090083]; regulation of neurotransmitter secretion [GO:0046928] cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; presynaptic membrane [GO:0042734]; synaptic vesicle [GO:0008021] identical protein binding [GO:0042802]; ubiquitin protein ligase binding [GO:0031625] 0.93144 -1.2508 KVEKTTPDCQLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.92753 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y6I4 UBP3_HUMAN Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.4.19.12) (Deubiquitinating enzyme 3) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) USP3 Homo sapiens (Human) cell cycle [GO:0007049]; DNA repair [GO:0006281]; DNA repair-dependent chromatin remodeling [GO:0140861]; histone deubiquitination [GO:0016578]; ubiquitin-dependent protein catabolic process [GO:0006511] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; Flemming body [GO:0090543]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] cysteine-type deubiquitinase activity [GO:0004843]; histone binding [GO:0042393]; zinc ion binding [GO:0008270] 0.91286 -0.74937 NKVDTYVEFPLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.44211 0 0 0 0 0 0 Q9Y6J0 CABIN_HUMAN Calcineurin-binding protein cabin-1 (Calcineurin inhibitor) (CAIN) CABIN1 KIAA0330 Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; nucleosome assembly [GO:0006334] aggresome [GO:0016235]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] protein phosphatase inhibitor activity [GO:0004864] 0.96947 -4.1711 APSSGSAQPPEGHPGKPEPSRAK 0 0 12.1882 0 0 0 0 12.2163 12.1759 0 0 0 11.7191 0 10.7586 0 0 0 0 0 0 0 0 0 0 12.2937 10.5226 Q9Y6K1 DNM3A_HUMAN DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) (EC 2.1.1.37) (Cysteine methyltransferase DNMT3A) (EC 2.1.1.-) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA) DNMT3A Homo sapiens (Human) aging [GO:0007568]; C-5 methylation of cytosine [GO:0090116]; cellular response to amino acid stimulus [GO:0071230]; cellular response to bisphenol A [GO:1903926]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; DNA methylation [GO:0006306]; DNA methylation involved in embryo development [GO:0043045]; DNA methylation involved in gamete generation [GO:0043046]; DNA methylation on cytosine [GO:0032776]; DNA methylation-dependent heterochromatin formation [GO:0006346]; hepatocyte apoptotic process [GO:0097284]; mitotic cell cycle [GO:0000278]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; positive regulation of cell death [GO:0010942]; regulation of gene expression by genomic imprinting [GO:0006349]; response to cocaine [GO:0042220]; response to estradiol [GO:0032355]; response to ionizing radiation [GO:0010212]; response to lead ion [GO:0010288]; response to toxic substance [GO:0009636]; response to vitamin A [GO:0033189]; response to xenobiotic stimulus [GO:0009410]; spermatogenesis [GO:0007283] "catalytic complex [GO:1902494]; chromosome, centromeric region [GO:0000775]; cytoplasm [GO:0005737]; euchromatin [GO:0000791]; heterochromatin [GO:0000792]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; XY body [GO:0001741]" chromatin binding [GO:0003682]; DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein-cysteine methyltransferase activity [GO:0106363]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription corepressor activity [GO:0003714] 0.94731 -1.3565 EIIDERTRER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.87702 0 9.87573 9.66695 0 0 0 0 0 Q9Y6K8 KAD5_HUMAN Adenylate kinase isoenzyme 5 (AK 5) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 5) AK5 Homo sapiens (Human) ADP biosynthetic process [GO:0006172]; ATP metabolic process [GO:0046034]; dADP biosynthetic process [GO:0006173]; nucleoside triphosphate biosynthetic process [GO:0009142]; phosphorylation [GO:0016310]; pyrimidine ribonucleotide biosynthetic process [GO:0009220] centriolar satellite [GO:0034451]; cytoplasm [GO:0005737]; cytosol [GO:0005829] adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550] 0.9548 -1.6207 ELGGCDKVK 0 0 0 0 0 0 0 9.00428 0 9.41037 0 9.54088 0 0 0 0 0 11.7055 0 0 0 0 0 0 0 0 0 Q9Y6K9 NEMO_HUMAN NF-kappa-B essential modulator (NEMO) (FIP-3) (IkB kinase-associated protein 1) (IKKAP1) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (I-kappa-B kinase subunit gamma) (IKK-gamma) (IKKG) (IkB kinase subunit gamma) (NF-kappa-B essential modifier) IKBKG FIP3 NEMO Homo sapiens (Human) anoikis [GO:0043276]; apoptotic process [GO:0006915]; DNA damage response [GO:0006974]; establishment of vesicle localization [GO:0051650]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of neuron death [GO:1901215]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein-containing complex assembly [GO:0065003]; response to virus [GO:0009615]; T cell receptor signaling pathway [GO:0050852] cytoplasm [GO:0005737]; cytosol [GO:0005829]; IkappaB kinase complex [GO:0008385]; mitotic spindle [GO:0072686]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle pole [GO:0000922]; ubiquitin ligase complex [GO:0000151] identical protein binding [GO:0042802]; K63-linked polyubiquitin modification-dependent protein binding [GO:0070530]; linear polyubiquitin binding [GO:1990450]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; transferrin receptor binding [GO:1990459]; ubiquitin protein ligase binding [GO:0031625] 0.96145 -2.5648 AASEQAR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.62781 0 0 0 0 0 0 0 0 0 0 10.2473 Q9Y6M5 ZNT1_HUMAN Proton-coupled zinc antiporter SLC30A1 (Solute carrier family 30 member 1) (Zinc transporter 1) SLC30A1 ZNT1 Homo sapiens (Human) cadmium ion transmembrane transport [GO:0070574]; calcium ion import [GO:0070509]; defense response to bacterium [GO:0042742]; detoxification of cadmium ion [GO:0071585]; detoxification of zinc ion [GO:0010312]; in utero embryonic development [GO:0001701]; intracellular calcium ion homeostasis [GO:0006874]; intracellular zinc ion homeostasis [GO:0006882]; negative regulation of calcium ion import [GO:0090281]; negative regulation of neurotransmitter secretion [GO:0046929]; negative regulation of zinc ion transmembrane import [GO:0071584]; zinc export across plasma membrane [GO:0140882]; zinc ion import into organelle [GO:0062111]; zinc ion transmembrane transport [GO:0071577]; zinc ion transport [GO:0006829] basolateral plasma membrane [GO:0016323]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; Schaffer collateral - CA1 synapse [GO:0098685]; T-tubule [GO:0030315] calcium channel inhibitor activity [GO:0019855]; metal ion binding [GO:0046872]; zinc ion transmembrane transporter activity [GO:0005385]; zinc:proton antiporter activity [GO:0140826] 0.96937 -3.3761 NTFGWIR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8.79854 0 0 0 0 0 0 Q9Y6M7 S4A7_HUMAN Sodium bicarbonate cotransporter 3 (Electroneutral Na/HCO(3) cotransporter) (Sodium bicarbonate cotransporter 2) (Sodium bicarbonate cotransporter 2b) (Bicarbonate transporter) (Solute carrier family 4 member 7) SLC4A7 BT NBC2 NBC2B NBC3 NBCn1 SBC2 SLC4A6 Homo sapiens (Human) auditory receptor cell development [GO:0060117]; bicarbonate transport [GO:0015701]; cellular response to growth factor stimulus [GO:0071363]; phagosome acidification [GO:0090383]; purine nucleotide biosynthetic process [GO:0006164]; pyrimidine nucleotide biosynthetic process [GO:0006221]; regulation of intracellular pH [GO:0051453]; transmembrane transport [GO:0055085] apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; membrane [GO:0016020]; plasma membrane [GO:0005886]; stereocilium [GO:0032420] monoatomic anion transmembrane transporter activity [GO:0008509]; sodium:bicarbonate symporter activity [GO:0008510]; solute:inorganic anion antiporter activity [GO:0005452] 0.5175 0.59651 SVPSQEKRK 0 0 0 0 0 0 0 0 0 0 0 0 8.90283 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y6N1 COX11_HUMAN "Cytochrome c oxidase assembly protein COX11, mitochondrial" COX11 Homo sapiens (Human) intracellular monoatomic cation homeostasis [GO:0030003]; negative regulation of glucokinase activity [GO:0033132] mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991] copper ion binding [GO:0005507]; electron transfer activity [GO:0009055] 0.58692 0.46705 VDLITLSYTFFEAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.38409 0 0 0 0 0 0 0 0 Q9Y6N3 CLCA3_HUMAN Calcium-activated chloride channel regulator family member 3 (Calcium-activated chloride channel family member 3) (hCLCA3) CLCA3P CLCA3 Homo sapiens (Human) monoatomic ion transmembrane transport [GO:0034220]; regulation of monoatomic ion transmembrane transport [GO:0034765] chloride channel complex [GO:0034707]; extracellular space [GO:0005615]; plasma membrane [GO:0005886] calcium channel activity [GO:0005262]; chloride channel activity [GO:0005254]; metalloendopeptidase activity [GO:0004222]; voltage-gated monoatomic ion channel activity [GO:0005244] 0.21662 0.8905 RDSQTGLYEAK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.0014 9.73557 Q9Y6N5 SQOR_HUMAN "Sulfide:quinone oxidoreductase, mitochondrial (SQOR) (EC 1.8.5.8) (Sulfide dehydrogenase-like) (Sulfide quinone oxidoreductase)" SQOR SQRDL CGI-44 Homo sapiens (Human) "sulfide oxidation, using sulfide:quinone oxidoreductase [GO:0070221]" mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] FAD binding [GO:0071949]; glutathione-dependent sulfide quinone oxidoreductase activity [GO:0106436]; quinone binding [GO:0048038]; sulfide:quinone oxidoreductase activity [GO:0070224] 0.96332 -2.1461 CAGAPQK 0 0 0 0 10.4266 0 0 0 0 9.08587 9.09181 0 0 0 0 0 0 0 0 9.19933 0 0 0 0 0 0 0 Q9Y6N7 ROBO1_HUMAN Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1) ROBO1 DUTT1 Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412] axon [GO:0030424]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; neuron projection [GO:0043005]; plasma membrane [GO:0005886] axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275] 0.92401 -1.016 SRYEIRDDHTLK 0 0 10.0203 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y6N8 CAD10_HUMAN Cadherin-10 (T2-cadherin) CDH10 Homo sapiens (Human) adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; synaptic membrane adhesion [GO:0099560] adherens junction [GO:0005912]; catenin complex [GO:0016342]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynaptic specialization membrane [GO:0099634]; presynaptic active zone membrane [GO:0048787] cadherin binding [GO:0045296]; calcium ion binding [GO:0005509] 0.94107 -1.3149 IDREEKAFYTLR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.21881 0 9.47131 0 0 0 0 0 0 Q9Y6N9 USH1C_HUMAN Harmonin (Antigen NY-CO-38/NY-CO-37) (Autoimmune enteropathy-related antigen AIE-75) (Protein PDZ-73) (Renal carcinoma antigen NY-REN-3) (Usher syndrome type-1C protein) USH1C AIE75 Homo sapiens (Human) actin filament bundle assembly [GO:0051017]; brush border assembly [GO:1904970]; equilibrioception [GO:0050957]; G2/M transition of mitotic cell cycle [GO:0000086]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear morphogenesis [GO:0042472]; inner ear receptor cell stereocilium organization [GO:0060122]; parallel actin filament bundle assembly [GO:0030046]; photoreceptor cell maintenance [GO:0045494]; protein localization to microvillus [GO:1904106]; protein-containing complex assembly [GO:0065003]; regulation of microvillus length [GO:0032532]; retinal cone cell development [GO:0046549]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605] apical part of cell [GO:0045177]; brush border [GO:0005903]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; microvillus [GO:0005902]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; stereocilia ankle link complex [GO:0002142]; stereocilium [GO:0032420]; stereocilium tip [GO:0032426]; synapse [GO:0045202] spectrin binding [GO:0030507] 0.93242 -1.2775 GSLGSPGNRENK 0 0 0 0 0 0 0 0 8.97757 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.2248 0 0 Q9Y6P5 SESN1_HUMAN Sestrin-1 (EC 1.11.1.-) (p53-regulated protein PA26) SESN1 PA26 SEST1 Homo sapiens (Human) cellular oxidant detoxification [GO:0098869]; cellular response to amino acid starvation [GO:0034198]; cellular response to glucose starvation [GO:0042149]; cellular response to leucine [GO:0071233]; cellular response to leucine starvation [GO:1990253]; negative regulation of TORC1 signaling [GO:1904262]; positive regulation of macroautophagy [GO:0016239]; reactive oxygen species metabolic process [GO:0072593]; regulation of response to reactive oxygen species [GO:1901031] cytoplasm [GO:0005737]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "leucine binding [GO:0070728]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]" 0.59165 0.44913 DEEEASQEEMASR 8.92107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.6146 Q9Y6Q1 CAN6_HUMAN Calpain-6 (Calpain-like protease X-linked) (Calpamodulin) (CalpM) CAPN6 CALPM CANPX Homo sapiens (Human) microtubule bundle formation [GO:0001578]; regulation of cytoskeleton organization [GO:0051493] cytoplasm [GO:0005737]; perinuclear region of cytoplasm [GO:0048471]; spindle microtubule [GO:0005876] calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; microtubule binding [GO:0008017] 0.93935 -1.3194 VIMSLQQKDLRTYR 0 9.96622 0 0 0 0 0 0 0 9.29292 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y6Q2 STON1_HUMAN Stonin-1 (Stoned B-like factor) STON1 SALF SBLF STN1 Homo sapiens (Human) clathrin-dependent endocytosis [GO:0072583]; focal adhesion assembly [GO:0048041]; focal adhesion disassembly [GO:0120181]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; regulation of endocytosis [GO:0030100]; ruffle assembly [GO:0097178]; substrate-dependent cell migration [GO:0006929]; synaptic vesicle endocytosis [GO:0048488] AP-2 adaptor complex [GO:0030122]; cell leading edge [GO:0031252]; cell projection [GO:0042995]; synaptic vesicle [GO:0008021] clathrin adaptor activity [GO:0035615] 0.91514 -0.81256 IPEKKNMMSSR 0 0 0 0 0 8.55781 0 0 0 0 0 0 0 9.86502 0 0 9.6115 0 0 0 0 0 0 0 0 0 0 Q9Y6Q3 ZFP37_HUMAN Zinc finger protein 37 homolog (Zfp-37) ZFP37 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; zinc ion binding [GO:0008270]" 0.95026 -1.4026 AFKYSSSLTKHMR 9.7252 9.48945 0 0 0 0 9.83488 0 0 0 0 0 0 0 0 0 9.2023 0 0 0 0 0 0 0 0 0 0 Q9Y6Q5 AP1M2_HUMAN AP-1 complex subunit mu-2 (AP-mu chain family member mu1B) (Adaptor protein complex AP-1 subunit mu-2) (Adaptor-related protein complex 1 subunit mu-2) (Clathrin assembly protein complex 1 mu-2 medium chain 2) (Golgi adaptor HA1/AP1 adaptin mu-2 subunit) (Mu-adaptin 2) (Mu1B-adaptin) AP1M2 Homo sapiens (Human) basolateral protein secretion [GO:0110010]; protein targeting [GO:0006605]; vesicle targeting [GO:0006903]; vesicle-mediated transport [GO:0016192] AP-1 adaptor complex [GO:0030121]; clathrin-coated vesicle [GO:0030136]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; trans-Golgi network membrane [GO:0032588] clathrin adaptor activity [GO:0035615] 0.78571 0.249 VFLSGMPELR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.9058 0 0 0 0 0 0 0 0 0 0 0 Q9Y6Q6 TNR11_HUMAN Tumor necrosis factor receptor superfamily member 11A (Osteoclast differentiation factor receptor) (ODFR) (Receptor activator of NF-KB) (CD antigen CD265) TNFRSF11A RANK Homo sapiens (Human) adaptive immune response [GO:0002250]; cell-cell signaling [GO:0007267]; cellular response to zinc ion starvation [GO:0034224]; circadian temperature homeostasis [GO:0060086]; lymph node development [GO:0048535]; mammary gland alveolus development [GO:0060749]; monocyte chemotaxis [GO:0002548]; multinuclear osteoclast differentiation [GO:0072674]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling [GO:0071848]; positive regulation of fever generation by positive regulation of prostaglandin secretion [GO:0071812]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoclast differentiation [GO:0045672]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to radiation [GO:0009314]; response to tumor necrosis factor [GO:0034612]; signal transduction [GO:0007165]; TNFSF11-mediated signaling pathway [GO:0071847]; tumor necrosis factor-mediated signaling pathway [GO:0033209] cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; membrane raft [GO:0045121]; plasma membrane [GO:0005886] cytokine binding [GO:0019955]; metal ion binding [GO:0046872]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; tumor necrosis factor receptor activity [GO:0005031] 0.94072 -1.328 HYEHLGRCCNK 0 0 13.7398 0 0 0 14.0258 13.9288 13.6702 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y6Q9 NCOA3_HUMAN Nuclear receptor coactivator 3 (NCoA-3) (EC 2.3.1.48) (ACTR) (Amplified in breast cancer 1 protein) (AIB-1) (CBP-interacting protein) (pCIP) (Class E basic helix-loop-helix protein 42) (bHLHe42) (Receptor-associated coactivator 3) (RAC-3) (Steroid receptor coactivator protein 3) (SRC-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) NCOA3 AIB1 BHLHE42 RAC3 TRAM1 Homo sapiens (Human) cell dedifferentiation [GO:0043697]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hormone stimulus [GO:0032870]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor transactivation [GO:0035624]; regulation of stem cell division [GO:2000035] chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991] disordered domain specific binding [GO:0097718]; histone acetyltransferase activity [GO:0004402]; molecular adaptor activity [GO:0060090]; nuclear receptor binding [GO:0016922]; nuclear receptor coactivator activity [GO:0030374]; nuclear thyroid hormone receptor binding [GO:0046966]; protein dimerization activity [GO:0046983]; RNA polymerase II complex binding [GO:0000993]; transcription coactivator activity [GO:0003713] 0.8968 -0.54513 ESKESSVEGAENQR 0 0 0 0 10.5361 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y6R4 M3K4_HUMAN Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) MAP3K4 KIAA0213 MAPKKK4 MEKK4 MTK1 Homo sapiens (Human) chorionic trophoblast cell differentiation [GO:0060718]; intracellular signal transduction [GO:0035556]; male germ-line sex determination [GO:0019100]; MAPK cascade [GO:0000165]; placenta development [GO:0001890]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein phosphorylation [GO:0006468]; regulation of gene expression [GO:0010468]; response to UV-C [GO:0010225] cytoplasm [GO:0005737]; perinuclear region of cytoplasm [GO:0048471] ATP binding [GO:0005524]; MAP kinase kinase kinase activity [GO:0004709]; metal ion binding [GO:0046872]; protein serine kinase activity [GO:0106310] 0.97031 -5.3295 DLEIAAEFR 0 0 0 0 0 0 0 0 0 10.96 0 11.1031 0 0 10.1957 0 9.43183 9.13394 0 0 0 0 8.87802 0 0 10.1435 10.105 Q9Y6R6 Z780B_HUMAN Zinc finger protein 780B (Zinc finger protein 779) ZNF780B ZNF779 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] nucleus [GO:0005634] "DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]" 0.9056 -0.72293 FFRRGSNLNQHR 0 0 0 0 13.4925 13.3112 0 0 0 0 0 0 13.5901 0 0 0 0 0 0 0 0 0 0 0 10.2209 0 0 Q9Y6R7 FCGBP_HUMAN IgGFc-binding protein (Fcgamma-binding protein antigen) (FcgammaBP) FCGBP Homo sapiens (Human) extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615] 0.96938 -3.9666 AGVQVWLGANGK 0 0 0 0 8.24332 0 0 0 0 0 0 0 0 0 0 10.0455 0 0 9.648 0 0 0 0 9.51231 0 0 0 Q9Y6R9 CCD61_HUMAN Centrosomal protein CCDC61 (Coiled-coil domain-containing protein 61) (VFL3 homolog) CCDC61 Homo sapiens (Human) cell projection organization [GO:0030030]; centriole assembly [GO:0098534]; mitotic spindle assembly [GO:0090307] centriolar satellite [GO:0034451]; centriolar subdistal appendage [GO:0120103]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; microtubule organizing center [GO:0005815] identical protein binding [GO:0042802]; microtubule binding [GO:0008017] 0.96981 -5.1293 ELEAQLGRSREEALAGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.9858 0 0 0 0 10.2841 Q9Y6U3 SCIN_HUMAN Scinderin (Adseverin) SCIN KIAA1905 Homo sapiens (Human) actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; actin polymerization or depolymerization [GO:0008154]; barbed-end actin filament capping [GO:0051016]; calcium-ion regulated exocytosis [GO:0017156]; cell projection assembly [GO:0030031]; central nervous system development [GO:0007417]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989] actin cytoskeleton [GO:0015629]; anchoring junction [GO:0070161]; brush border [GO:0005903]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; podosome [GO:0002102] "1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]" 0.96943 -5.7084 ELYHEEFARAGK 0 0 0 0 0 10.2987 0 0 0 12.3128 0 0 0 0 0 0 0 0 0 0 0 9.00848 0 0 0 0 10.4813 Q9Y6V0 PCLO_HUMAN Protein piccolo (Aczonin) PCLO ACZ KIAA0559 Homo sapiens (Human) cytoskeleton organization [GO:0007010]; insulin secretion [GO:0030073]; presynapse to nucleus signaling pathway [GO:0099526]; presynaptic active zone assembly [GO:1904071]; protein localization to synapse [GO:0035418]; regulation of exocytosis [GO:0017157]; synaptic vesicle clustering [GO:0097091]; synaptic vesicle exocytosis [GO:0016079] axon [GO:0030424]; cytoskeleton [GO:0005856]; cytoskeleton of presynaptic active zone [GO:0048788]; extracellular exosome [GO:0070062]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; postsynaptic density [GO:0014069]; synapse [GO:0045202] calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; profilin binding [GO:0005522]; structural constituent of presynaptic active zone [GO:0098882] 0.96828 -9.5141 AFPAANERDEVFEK 18.0621 18.2398 18.2092 15.8931 16.2595 16.2341 17.9456 18.0893 18.0463 17.7623 17.3501 17.1314 16.0629 16.29 16.2094 16.7991 17.0014 16.3999 13.2935 13.3558 12.9781 13.1688 12.4671 12.7054 13.3083 13.6678 12.798 Q9Y6W3 CAN7_HUMAN Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH) CAPN7 PALBH Homo sapiens (Human) positive regulation of epithelial cell migration [GO:0010634]; proteolysis [GO:0006508]; self proteolysis [GO:0097264] centrosome [GO:0005813]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634] calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; cysteine-type endopeptidase activity [GO:0004197]; endopeptidase activity [GO:0004175]; MIT domain binding [GO:0090541] 0.92603 -0.96576 QGPVKDAYSLANNPQYK 0 0 0 0 0 0 0 0 0 0 0 11.0849 10.8181 0 0 0 0 0 0 0 0 0 9.58984 0 0 0 0 Q9Y6X0 SETBP_HUMAN SET-binding protein (SEB) SETBP1 KIAA0437 Homo sapiens (Human) histone H3-K36 dimethylation [GO:0097676]; regulation of DNA-templated transcription [GO:0006355] cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654] DNA binding [GO:0003677]; histone H3K4 methyltransferase activity [GO:0042800] 0.88412 -0.043852 ILSNSEGNKK 0 0 0 0 0 10.0937 0 0 0 15.3366 0 0 0 0 0 0 0 0 0 10.78 0 0 0 0 0 0 0 Q9Y6X4 F169A_HUMAN Soluble lamin-associated protein of 75 kDa (SLAP75) (Protein FAM169A) FAM169A KIAA0888 Homo sapiens (Human) nuclear inner membrane [GO:0005637] 0.9304 -1.2337 IIYRKQEMER 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.1481 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y6X5 ENPP4_HUMAN Bis(5'-adenosyl)-triphosphatase ENPP4 (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Ectonucleotide pyrophosphatase/phosphodiesterase family member 4) (E-NPP 4) (NPP-4) ENPP4 KIAA0879 NPP4 Homo sapiens (Human) blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; purine ribonucleoside catabolic process [GO:0046130] extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; membrane [GO:0016020]; plasma membrane [GO:0005886] bis(5'-adenosyl)-triphosphatase activity [GO:0047710]; metal ion binding [GO:0046872] 0.74867 0.31275 EGVLVEHVK 0 0 9.31771 0 9.29235 0 0 0 0 0 9.99661 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y6X6 MYO16_HUMAN Unconventional myosin-XVI (Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3) (Unconventional myosin-16) MYO16 KIAA0865 MYO16B NYAP3 Homo sapiens (Human) cerebellum development [GO:0021549]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; neuron projection morphogenesis [GO:0048812]; phosphatidylinositol 3-kinase signaling [GO:0014065] cytoplasm [GO:0005737]; myosin complex [GO:0016459]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] actin filament binding [GO:0051015]; ATP binding [GO:0005524]; cytoskeletal motor activity [GO:0003774]; protein phosphatase binding [GO:0019903] 0.55856 0.55267 AEIAWEEKMK 10.0852 0 0 0 8.66021 0 0 0 0 0 11.2186 0 0 0 0 0 0 0 0 0 8.54435 0 0 0 0 0 0 Q9Y6X8 ZHX2_HUMAN Zinc fingers and homeoboxes protein 2 (Alpha-fetoprotein regulator 1) (AFP regulator 1) (Regulator of AFP) (Zinc finger and homeodomain protein 2) ZHX2 AFR1 KIAA0854 RAF Homo sapiens (Human) mRNA catabolic process [GO:0006402]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357]; retinal bipolar neuron differentiation [GO:0060040]; somatic stem cell population maintenance [GO:0035019] chromatin [GO:0000785]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] "DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]" 0.84111 0.14645 ATKPMAESPK 0 0 0 0 9.63427 0 0 0 0 0 0 0 0 0 0 0 0 8.87344 10.5234 0 0 0 9.63849 0 8.80426 9.18249 9.05783 Q9Y6X9 MORC2_HUMAN ATPase MORC2 (EC 3.6.1.-) (MORC family CW-type zinc finger protein 2) (Zinc finger CW-type coiled-coil domain protein 1) MORC2 KIAA0852 ZCWCC1 Homo sapiens (Human) "chromatin remodeling [GO:0006338]; DNA damage response [GO:0006974]; fatty acid metabolic process [GO:0006631]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309]" cytoplasm [GO:0005737]; cytosol [GO:0005829]; heterochromatin [GO:0000792]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; chromatin binding [GO:0003682]; histone binding [GO:0042393]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270] 0.96943 -6.3041 AKASEESLR 0 0 0 11.4246 0 11.7583 10.1722 0 0 10.4851 0 0 0 0 0 0 0 0 9.47474 0 0 8.82991 8.23343 0 0 0 10.1392 Q9Y6Y0 NS1BP_HUMAN Influenza virus NS1A-binding protein (NS1-BP) (NS1-binding protein) (Aryl hydrocarbon receptor-associated protein 3) (Kelch-like protein 39) IVNS1ABP ARA3 FLARA3 KIAA0850 KLHL39 NS1 NS1BP HSPC068 Homo sapiens (Human) intrinsic apoptotic signaling pathway [GO:0097193]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of protein ubiquitination [GO:0031397]; response to virus [GO:0009615]; RNA splicing [GO:0008380]; transcription by RNA polymerase III [GO:0006383] cytoskeleton [GO:0005856]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; transcription regulator complex [GO:0005667] 0.96164 -2.5603 DVYSAAK 0 0 0 0 0 0 0 0 0 0 9.01633 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q9Y6Y1 CMTA1_HUMAN Calmodulin-binding transcription activator 1 CAMTA1 KIAA0833 MSTP023 Homo sapiens (Human) neuromuscular process controlling balance [GO:0050885]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleus [GO:0005634] double-stranded DNA binding [GO:0003690]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712] 0.88904 -0.41669 DLYIGVSTVQVTGNPK 0 0 0 0 0 0 0 0 0 0 0 13.8924 0 0 0 0 0 0 10.1864 0 0 0 0 0 0 0 0 Q9Y6Y8 S23IP_HUMAN SEC23-interacting protein (p125) SEC23IP MSTP053 Homo sapiens (Human) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886] COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231] metal ion binding [GO:0046872]; RNA binding [GO:0003723] 0.49216 0.61728 AVTTNQWHRR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.26252 0 0 0 0 0 0 Q9Y6Z4 KIAS1_HUMAN Putative uncharacterized protein KIF25-AS1 (KIF25 antisense RNA 1) (KIF25 antisense gene protein 1) (Protein HGC6.1) KIF25-AS1 C6orf54 NCRNA00300 Homo sapiens (Human) 0.87061 0.034547 GGSVSVTWSSVSCCRGR 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.19293 0 Q9Y6Z5 AFDDT_HUMAN Putative uncharacterized protein AFDN-DT (AFDN divergent transcript) (Protein HGC6.4) AFDN-DT AFDN-AS1 C6orf124 Homo sapiens (Human) 0.64192 0.39646 TGGAGSK 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.605 0 0 0 0 Q9Y6Z7 COL10_HUMAN Collectin-10 (Collectin liver protein 1) (CL-L1) (Collectin-34) (CL-34) COLEC10 CLL1 UNQ366/PRO702 Homo sapiens (Human) "cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; cranial skeletal system development [GO:1904888]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508]" collagen trimer [GO:0005581]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; serine-type endopeptidase complex [GO:1905370] chemoattractant activity [GO:0042056]; mannose binding [GO:0005537] 0.95264 -1.465 ESLTHCRIR 0 0 9.35253 0 0 0 0 9.50736 0 0 0 0 0 0 0 0 0 0 0 0 8.7878 0 0 0 0 0 0 U3KPV4 A3LT2_HUMAN "Alpha-1,3-galactosyltransferase 2 (EC 2.4.1.87) (Isoglobotriaosylceramide synthase) (iGb3 synthase) (iGb3S)" A3GALT2 A3GALT2P IGBS3S Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; cellular response to manganese ion [GO:0071287]; glycosphingolipid biosynthetic process [GO:0006688]; lipid glycosylation [GO:0030259] Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; vesicle [GO:0031982] glycosyltransferase activity [GO:0016757]; metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276] 0.92026 -0.91665 ERRWQDVSMAR 15.5361 15.5343 15.4368 14.7399 14.7984 14.4558 14.6853 15.3382 15.6504 14.0045 13.8222 14.7936 13.5203 13.9796 13.8028 14.3447 14.2671 12.9932 10.8903 11.1264 0 10.8022 10.4768 10.5973 11.1956 10.7944 10.0932 X6R8R1 ST15B_HUMAN Synaptotagmin-15B SYT15B Homo sapiens (Human) 0.91021 -0.74654 FPEDKSETDFPDGCLGR 0 0 0 0 0 9.68774 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0